ORF_ID e_value Gene_name EC_number CAZy COGs Description
KOKCBKAK_00001 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_00002 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_00003 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KOKCBKAK_00004 3.1e-69 argR K Regulates arginine biosynthesis genes
KOKCBKAK_00005 3.3e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KOKCBKAK_00006 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KOKCBKAK_00007 1.2e-79 S Protein of unknown function (DUF3021)
KOKCBKAK_00008 5.3e-72 K LytTr DNA-binding domain
KOKCBKAK_00010 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KOKCBKAK_00012 5.9e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KOKCBKAK_00013 2.2e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KOKCBKAK_00014 1.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
KOKCBKAK_00015 6.1e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KOKCBKAK_00016 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KOKCBKAK_00018 1.9e-88 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_00019 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KOKCBKAK_00020 2.4e-37 ylqC L Belongs to the UPF0109 family
KOKCBKAK_00021 4.2e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KOKCBKAK_00022 0.0 ydaO E amino acid
KOKCBKAK_00023 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
KOKCBKAK_00024 5e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KOKCBKAK_00025 4.2e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KOKCBKAK_00026 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KOKCBKAK_00027 6.3e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KOKCBKAK_00028 1.6e-168 murB 1.3.1.98 M cell wall formation
KOKCBKAK_00029 2e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KOKCBKAK_00030 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
KOKCBKAK_00031 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
KOKCBKAK_00032 1.8e-203 potD P spermidine putrescine ABC transporter
KOKCBKAK_00033 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_00034 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_00035 1.4e-16 3.2.1.51 GH95 U LPXTG cell wall anchor motif
KOKCBKAK_00036 1.5e-109 K Helix-turn-helix domain, rpiR family
KOKCBKAK_00037 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KOKCBKAK_00038 0.0 3.5.1.28 M domain protein
KOKCBKAK_00039 8.8e-144 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
KOKCBKAK_00040 3.2e-90 maa 2.3.1.79 GK Maltose O-acetyltransferase
KOKCBKAK_00041 3.3e-68 rmaI K Transcriptional regulator, MarR family
KOKCBKAK_00042 2.2e-241 EGP Major facilitator Superfamily
KOKCBKAK_00043 3e-131 XK27_00785 S CAAX protease self-immunity
KOKCBKAK_00045 0.0 S dextransucrase activity
KOKCBKAK_00046 0.0 S dextransucrase activity
KOKCBKAK_00047 1.4e-286 S dextransucrase activity
KOKCBKAK_00048 0.0 M Putative cell wall binding repeat
KOKCBKAK_00049 2.4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KOKCBKAK_00050 4.6e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KOKCBKAK_00051 0.0 S dextransucrase activity
KOKCBKAK_00052 1.4e-236 tcdB S dextransucrase activity
KOKCBKAK_00053 0.0 M Putative cell wall binding repeat
KOKCBKAK_00054 8.5e-82 S dextransucrase activity
KOKCBKAK_00055 0.0 S dextransucrase activity
KOKCBKAK_00056 0.0 S dextransucrase activity
KOKCBKAK_00057 0.0 S dextransucrase activity
KOKCBKAK_00058 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KOKCBKAK_00059 1.6e-240 S dextransucrase activity
KOKCBKAK_00061 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KOKCBKAK_00062 2e-116 yhfC S Putative membrane peptidase family (DUF2324)
KOKCBKAK_00063 2.5e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
KOKCBKAK_00064 5.5e-16 S integral membrane protein
KOKCBKAK_00065 2.4e-08 S Enterocin A Immunity
KOKCBKAK_00066 0.0 pepO 3.4.24.71 O Peptidase family M13
KOKCBKAK_00067 2.1e-33 S Immunity protein 41
KOKCBKAK_00068 1.4e-79 M Putative cell wall binding repeat
KOKCBKAK_00069 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_00070 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_00071 1.8e-68 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_00072 1.9e-124 K sequence-specific DNA binding
KOKCBKAK_00073 1.2e-09
KOKCBKAK_00075 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KOKCBKAK_00076 4e-133 agrA KT response regulator
KOKCBKAK_00077 1.6e-228 2.7.13.3 T GHKL domain
KOKCBKAK_00079 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
KOKCBKAK_00080 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KOKCBKAK_00081 2.9e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KOKCBKAK_00082 5.9e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KOKCBKAK_00083 1.3e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KOKCBKAK_00084 5.6e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KOKCBKAK_00085 1.1e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KOKCBKAK_00086 3.6e-128 yxkH G deacetylase
KOKCBKAK_00087 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KOKCBKAK_00088 3.7e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KOKCBKAK_00089 1.3e-149 rarD S Transporter
KOKCBKAK_00090 2e-16 T peptidase
KOKCBKAK_00091 3e-14 coiA 3.6.4.12 S Competence protein
KOKCBKAK_00092 2.7e-108 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KOKCBKAK_00093 5.9e-108 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KOKCBKAK_00094 1.6e-174 S Helix-hairpin-helix DNA-binding motif class 1
KOKCBKAK_00095 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KOKCBKAK_00096 1.2e-25 S AAA domain
KOKCBKAK_00097 2.2e-55 lrgA S Effector of murein hydrolase LrgA
KOKCBKAK_00098 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KOKCBKAK_00099 1.4e-98 3.1.3.18 S IA, variant 1
KOKCBKAK_00100 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOKCBKAK_00101 6e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KOKCBKAK_00102 2.2e-114 serB 3.1.3.3 E phosphoserine phosphatase
KOKCBKAK_00103 3.2e-07 N PFAM Uncharacterised protein family UPF0150
KOKCBKAK_00104 1.1e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
KOKCBKAK_00106 4.3e-59 ycaO O OsmC-like protein
KOKCBKAK_00107 9.6e-62 paaI Q protein possibly involved in aromatic compounds catabolism
KOKCBKAK_00108 4.4e-10 O ADP-ribosylglycohydrolase
KOKCBKAK_00109 7.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOKCBKAK_00111 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KOKCBKAK_00112 1.7e-17 XK27_00735
KOKCBKAK_00113 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOKCBKAK_00114 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KOKCBKAK_00115 3.8e-168 S CAAX amino terminal protease family protein
KOKCBKAK_00117 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOKCBKAK_00118 1.3e-84 mutT 3.6.1.55 F Nudix family
KOKCBKAK_00119 3.8e-140 ET ABC transporter
KOKCBKAK_00120 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
KOKCBKAK_00121 3.3e-211 arcT 2.6.1.1 E Aminotransferase
KOKCBKAK_00122 1.9e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
KOKCBKAK_00123 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KOKCBKAK_00124 8.9e-44 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KOKCBKAK_00125 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KOKCBKAK_00126 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KOKCBKAK_00127 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KOKCBKAK_00128 2.5e-172 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KOKCBKAK_00129 3.8e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KOKCBKAK_00130 4e-212 rgpA GT4 M Domain of unknown function (DUF1972)
KOKCBKAK_00131 4.2e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
KOKCBKAK_00132 5.2e-142 rgpC GM Transport permease protein
KOKCBKAK_00133 2e-222 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KOKCBKAK_00134 9.2e-184 rgpEc GT2 M Glycosyl transferase family 2
KOKCBKAK_00135 0.0 rgpF M Rhamnan synthesis protein F
KOKCBKAK_00136 4.3e-156 rfbJ M Glycosyl transferase family 2
KOKCBKAK_00137 4.3e-46 M Psort location CytoplasmicMembrane, score
KOKCBKAK_00138 2.6e-166
KOKCBKAK_00139 1.8e-114 radC E Belongs to the UPF0758 family
KOKCBKAK_00140 1.8e-127 puuD T peptidase C26
KOKCBKAK_00141 6.2e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KOKCBKAK_00142 4.1e-59 XK27_04120 S Putative amino acid metabolism
KOKCBKAK_00143 6.9e-201 iscS 2.8.1.7 E Cysteine desulfurase
KOKCBKAK_00144 6.6e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOKCBKAK_00145 7.8e-100 yjbK S Adenylate cyclase
KOKCBKAK_00146 2e-118 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KOKCBKAK_00147 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KOKCBKAK_00148 3.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KOKCBKAK_00149 9.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KOKCBKAK_00150 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KOKCBKAK_00151 5.5e-311 amiA E ABC transporter, substrate-binding protein, family 5
KOKCBKAK_00152 7.1e-278 amiC P ABC transporter (Permease
KOKCBKAK_00153 1.4e-167 amiD P ABC transporter (Permease
KOKCBKAK_00154 1.6e-202 oppD P Belongs to the ABC transporter superfamily
KOKCBKAK_00155 1.2e-171 oppF P Belongs to the ABC transporter superfamily
KOKCBKAK_00156 5.8e-130 V Psort location CytoplasmicMembrane, score
KOKCBKAK_00157 4.1e-119 skfE V abc transporter atp-binding protein
KOKCBKAK_00158 5.6e-62 yvoA_1 K Transcriptional
KOKCBKAK_00159 2.6e-146 supH S overlaps another CDS with the same product name
KOKCBKAK_00160 2.3e-145 XK27_02985 S overlaps another CDS with the same product name
KOKCBKAK_00161 9.2e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KOKCBKAK_00162 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KOKCBKAK_00163 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KOKCBKAK_00164 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KOKCBKAK_00165 8.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KOKCBKAK_00166 1.6e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KOKCBKAK_00167 4.8e-137 stp 3.1.3.16 T phosphatase
KOKCBKAK_00168 8.9e-302 prkC 2.7.11.1 KLT serine threonine protein kinase
KOKCBKAK_00169 1.2e-103 kcsA P Ion transport protein
KOKCBKAK_00170 8.6e-117 yvqF S Membrane
KOKCBKAK_00171 3.9e-171 vraS 2.7.13.3 T Histidine kinase
KOKCBKAK_00172 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOKCBKAK_00175 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KOKCBKAK_00176 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KOKCBKAK_00177 8.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KOKCBKAK_00178 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KOKCBKAK_00179 3.2e-231 L Transposase
KOKCBKAK_00180 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_00181 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_00182 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KOKCBKAK_00183 9.6e-135 J Domain of unknown function (DUF4041)
KOKCBKAK_00184 6.6e-34
KOKCBKAK_00185 1.3e-139 1.1.1.169 H Ketopantoate reductase
KOKCBKAK_00186 2.3e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KOKCBKAK_00187 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KOKCBKAK_00188 1.4e-239 purD 6.3.4.13 F Belongs to the GARS family
KOKCBKAK_00189 6.6e-156 S CHAP domain
KOKCBKAK_00190 2.8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KOKCBKAK_00191 6.8e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KOKCBKAK_00192 1.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KOKCBKAK_00193 2.4e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KOKCBKAK_00194 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOKCBKAK_00195 2.6e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KOKCBKAK_00196 1.8e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOKCBKAK_00197 9.5e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KOKCBKAK_00198 6.1e-140 recO L Involved in DNA repair and RecF pathway recombination
KOKCBKAK_00199 1.9e-217 araT 2.6.1.1 E Aminotransferase
KOKCBKAK_00200 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOKCBKAK_00201 2.2e-87 usp 3.5.1.28 CBM50 S CHAP domain
KOKCBKAK_00202 4.2e-84 mreD M rod shape-determining protein MreD
KOKCBKAK_00203 9.2e-110 mreC M Involved in formation and maintenance of cell shape
KOKCBKAK_00209 2.6e-10
KOKCBKAK_00221 0.0 M Putative cell wall binding repeat
KOKCBKAK_00222 7.7e-225 thrE K Psort location CytoplasmicMembrane, score
KOKCBKAK_00223 1.2e-177 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
KOKCBKAK_00224 2.4e-96 dhaL 2.7.1.121 S Dihydroxyacetone kinase
KOKCBKAK_00225 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
KOKCBKAK_00226 6.7e-176 XK27_10475 S oxidoreductase
KOKCBKAK_00227 1.1e-195 gldA 1.1.1.6 C glycerol dehydrogenase
KOKCBKAK_00229 7.3e-283 XK27_07020 S Belongs to the UPF0371 family
KOKCBKAK_00230 2.2e-179 vex1 V Efflux ABC transporter, permease protein
KOKCBKAK_00231 5e-108 vex2 V abc transporter atp-binding protein
KOKCBKAK_00232 1.3e-233 vex3 V Efflux ABC transporter, permease protein
KOKCBKAK_00233 8.9e-116 K Response regulator receiver domain protein
KOKCBKAK_00234 2.1e-225 vncS 2.7.13.3 T Histidine kinase
KOKCBKAK_00235 1.4e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
KOKCBKAK_00236 5.4e-175 L Integrase
KOKCBKAK_00237 3.2e-181 galR K Transcriptional regulator
KOKCBKAK_00238 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KOKCBKAK_00239 3.2e-286 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KOKCBKAK_00240 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOKCBKAK_00241 4.6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KOKCBKAK_00242 0.0 lacS G transporter
KOKCBKAK_00243 0.0 lacL 3.2.1.23 G -beta-galactosidase
KOKCBKAK_00244 3.2e-209 S Tetratricopeptide repeat
KOKCBKAK_00245 1.3e-156 yvgN C reductase
KOKCBKAK_00246 4.2e-30 XK27_10490
KOKCBKAK_00247 4.5e-39 DJ nuclease activity
KOKCBKAK_00248 1.6e-104 yoaK S Protein of unknown function (DUF1275)
KOKCBKAK_00249 4.1e-110 drgA C nitroreductase
KOKCBKAK_00250 4e-119 T Xre family transcriptional regulator
KOKCBKAK_00251 6.7e-127 T PhoQ Sensor
KOKCBKAK_00252 4.3e-45 S Domain of unknown function (DUF4352)
KOKCBKAK_00253 2.3e-128 S ABC-2 family transporter protein
KOKCBKAK_00254 1.7e-168 bcrA V abc transporter atp-binding protein
KOKCBKAK_00255 5.3e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOKCBKAK_00256 4.9e-154 E Alpha/beta hydrolase of unknown function (DUF915)
KOKCBKAK_00257 4.7e-76 ywnA K Transcriptional regulator
KOKCBKAK_00258 1.5e-152 1.13.11.2 S glyoxalase
KOKCBKAK_00259 2.2e-108 XK27_02070 S nitroreductase
KOKCBKAK_00260 7.3e-28
KOKCBKAK_00261 2.5e-27 XK27_07105 K transcriptional
KOKCBKAK_00262 9.8e-08 S Protein of unknown function (DUF3169)
KOKCBKAK_00263 3.4e-169 ydhF S Aldo keto reductase
KOKCBKAK_00264 2.1e-97 K WHG domain
KOKCBKAK_00265 6.6e-122 V abc transporter atp-binding protein
KOKCBKAK_00266 8.9e-204 P FtsX-like permease family
KOKCBKAK_00267 1.5e-42 S Sugar efflux transporter for intercellular exchange
KOKCBKAK_00268 2.3e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KOKCBKAK_00269 9.5e-178 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
KOKCBKAK_00270 4e-164 ET ABC transporter substrate-binding protein
KOKCBKAK_00271 9.1e-111 ytmL P ABC transporter (Permease
KOKCBKAK_00272 6e-115 yxeN P ABC transporter, permease protein
KOKCBKAK_00273 1.3e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
KOKCBKAK_00275 4e-60 M Putative cell wall binding repeat
KOKCBKAK_00276 0.0 S dextransucrase activity
KOKCBKAK_00277 2.1e-215 yfnA E amino acid
KOKCBKAK_00278 1.4e-51 XK27_01300 S ASCH
KOKCBKAK_00279 1.3e-122 S Carbohydrate-binding domain-containing protein Cthe_2159
KOKCBKAK_00280 1.4e-16 csbD S CsbD-like
KOKCBKAK_00281 1.5e-107 S Protein of unknown function (DUF421)
KOKCBKAK_00282 1.8e-59 S Protein of unknown function (DUF3290)
KOKCBKAK_00283 1e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
KOKCBKAK_00284 3.1e-232 brnQ E Component of the transport system for branched-chain amino acids
KOKCBKAK_00285 1.5e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOKCBKAK_00287 8.7e-243 norM V Multidrug efflux pump
KOKCBKAK_00288 4.7e-154 K sequence-specific DNA binding
KOKCBKAK_00289 4e-271 V (ABC) transporter
KOKCBKAK_00290 2.1e-222 pbuX F xanthine permease
KOKCBKAK_00291 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KOKCBKAK_00292 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOKCBKAK_00293 1.2e-161 T Histidine kinase
KOKCBKAK_00294 4.6e-132 macB2 V ABC transporter, ATP-binding protein
KOKCBKAK_00295 0.0 V ABC transporter (permease)
KOKCBKAK_00296 6.1e-93 XK27_05000 S metal cluster binding
KOKCBKAK_00297 1.2e-30 liaI KT membrane
KOKCBKAK_00298 4.1e-15 liaI KT membrane
KOKCBKAK_00299 5.3e-156 XK27_09825 V abc transporter atp-binding protein
KOKCBKAK_00300 3.1e-117 yvfS V Transporter
KOKCBKAK_00301 8.9e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KOKCBKAK_00302 2.3e-165 yocS S Transporter
KOKCBKAK_00305 2.1e-160 XK27_09825 V 'abc transporter, ATP-binding protein
KOKCBKAK_00306 2.4e-133 yvfS V ABC-2 type transporter
KOKCBKAK_00307 1e-188 desK 2.7.13.3 T Histidine kinase
KOKCBKAK_00308 2.4e-99 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOKCBKAK_00309 4e-184 S abc transporter atp-binding protein
KOKCBKAK_00310 4e-142 S ABC-2 family transporter protein
KOKCBKAK_00311 1.6e-140 S ABC-2 family transporter protein
KOKCBKAK_00312 2e-77 K Acetyltransferase (GNAT) domain
KOKCBKAK_00313 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
KOKCBKAK_00314 1e-50 ywrO S general stress protein
KOKCBKAK_00315 6.9e-159 K sequence-specific DNA binding
KOKCBKAK_00316 2.1e-80 3.4.21.89 S RDD family
KOKCBKAK_00317 3.2e-164 yjlA EG membrane
KOKCBKAK_00318 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
KOKCBKAK_00319 1.7e-146 sdaAA 4.3.1.17 E L-serine dehydratase
KOKCBKAK_00320 2.5e-121 sdaAB 4.3.1.17 E L-serine dehydratase
KOKCBKAK_00321 1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KOKCBKAK_00322 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KOKCBKAK_00323 4.2e-53
KOKCBKAK_00324 1.9e-278 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KOKCBKAK_00325 6.3e-163 L PFAM Integrase catalytic region
KOKCBKAK_00326 4.8e-271 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KOKCBKAK_00327 5.2e-87 pat 2.3.1.183 M acetyltransferase
KOKCBKAK_00328 5.7e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KOKCBKAK_00329 1e-119 alkD L DNA alkylation repair enzyme
KOKCBKAK_00330 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KOKCBKAK_00331 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KOKCBKAK_00332 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KOKCBKAK_00333 0.0 smc D Required for chromosome condensation and partitioning
KOKCBKAK_00334 1e-93 S Protein of unknown function (DUF3278)
KOKCBKAK_00335 2.9e-22 WQ51_00220 K Helix-turn-helix domain
KOKCBKAK_00336 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KOKCBKAK_00337 1.7e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOKCBKAK_00338 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOKCBKAK_00340 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KOKCBKAK_00341 3e-237 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KOKCBKAK_00343 5.7e-86 S ECF-type riboflavin transporter, S component
KOKCBKAK_00344 5.9e-152 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KOKCBKAK_00345 6.1e-83 XK27_01265 S ECF-type riboflavin transporter, S component
KOKCBKAK_00346 1.5e-294 yfmM S abc transporter atp-binding protein
KOKCBKAK_00347 1.4e-256 noxE P NADH oxidase
KOKCBKAK_00348 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KOKCBKAK_00349 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOKCBKAK_00350 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KOKCBKAK_00351 3.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
KOKCBKAK_00352 5.8e-164 ypuA S secreted protein
KOKCBKAK_00353 2.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
KOKCBKAK_00354 4.4e-45 rpmE2 J 50S ribosomal protein L31
KOKCBKAK_00355 2.9e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KOKCBKAK_00356 1.9e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KOKCBKAK_00357 7.8e-151 gst O Glutathione S-transferase
KOKCBKAK_00358 3e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KOKCBKAK_00359 2.8e-108 tdk 2.7.1.21 F thymidine kinase
KOKCBKAK_00360 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KOKCBKAK_00361 2.9e-148 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KOKCBKAK_00362 2.8e-100 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KOKCBKAK_00363 1.4e-61 XK27_05710 K Acetyltransferase (GNAT) domain
KOKCBKAK_00364 1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KOKCBKAK_00365 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
KOKCBKAK_00366 1.9e-99 pvaA M lytic transglycosylase activity
KOKCBKAK_00367 5.9e-292 yfiB1 V abc transporter atp-binding protein
KOKCBKAK_00368 0.0 XK27_10035 V abc transporter atp-binding protein
KOKCBKAK_00369 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOKCBKAK_00370 1.2e-235 dltB M Membrane protein involved in D-alanine export
KOKCBKAK_00371 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOKCBKAK_00372 2.2e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KOKCBKAK_00373 0.0 3.6.3.8 P cation transport ATPase
KOKCBKAK_00374 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KOKCBKAK_00376 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KOKCBKAK_00377 2.8e-165 metF 1.5.1.20 E reductase
KOKCBKAK_00378 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KOKCBKAK_00379 3.8e-91 panT S Psort location CytoplasmicMembrane, score
KOKCBKAK_00380 1.2e-92 panT S ECF transporter, substrate-specific component
KOKCBKAK_00381 2.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KOKCBKAK_00382 1.9e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KOKCBKAK_00383 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KOKCBKAK_00384 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOKCBKAK_00385 8.3e-236 T PhoQ Sensor
KOKCBKAK_00386 2.3e-29 rpsT J Binds directly to 16S ribosomal RNA
KOKCBKAK_00387 1e-170 coaA 2.7.1.33 F Pantothenic acid kinase
KOKCBKAK_00388 9.2e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
KOKCBKAK_00389 5.6e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KOKCBKAK_00390 2.1e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KOKCBKAK_00391 3.1e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KOKCBKAK_00392 4.7e-191 tcsA S membrane
KOKCBKAK_00393 2.9e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KOKCBKAK_00394 1.9e-176 yufP S Belongs to the binding-protein-dependent transport system permease family
KOKCBKAK_00395 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KOKCBKAK_00396 5.8e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KOKCBKAK_00397 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KOKCBKAK_00398 1.5e-80 ypmB S Protein conserved in bacteria
KOKCBKAK_00399 1e-210 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KOKCBKAK_00400 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KOKCBKAK_00401 1.4e-18
KOKCBKAK_00402 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KOKCBKAK_00403 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KOKCBKAK_00404 3.3e-82 queD 4.1.2.50, 4.2.3.12 H synthase
KOKCBKAK_00405 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KOKCBKAK_00406 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KOKCBKAK_00407 5.6e-201 D nuclear chromosome segregation
KOKCBKAK_00408 1.4e-136 yejC S cyclic nucleotide-binding protein
KOKCBKAK_00409 7e-164 rapZ S Displays ATPase and GTPase activities
KOKCBKAK_00410 4.3e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KOKCBKAK_00411 2.2e-160 whiA K May be required for sporulation
KOKCBKAK_00412 1.1e-275 pepD E Dipeptidase
KOKCBKAK_00413 3.5e-146 XK27_10720 D peptidase activity
KOKCBKAK_00414 2.3e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
KOKCBKAK_00415 2.6e-09
KOKCBKAK_00417 7.4e-170 yeiH S Membrane
KOKCBKAK_00418 1.3e-128 mur1 3.4.17.14, 3.5.1.28 NU muramidase
KOKCBKAK_00419 2.9e-165 cpsY K Transcriptional regulator
KOKCBKAK_00420 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KOKCBKAK_00421 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
KOKCBKAK_00422 1.4e-105 artQ P ABC transporter (Permease
KOKCBKAK_00423 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOKCBKAK_00424 4.9e-159 aatB ET ABC transporter substrate-binding protein
KOKCBKAK_00425 2.1e-271 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOKCBKAK_00426 2.6e-51
KOKCBKAK_00427 1.9e-46
KOKCBKAK_00428 3e-57 adhP 1.1.1.1 P alcohol dehydrogenase
KOKCBKAK_00429 2.3e-31 adhP 1.1.1.1 P alcohol dehydrogenase
KOKCBKAK_00430 5.1e-107 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KOKCBKAK_00431 4.1e-189 L PFAM Integrase, catalytic core
KOKCBKAK_00432 1.3e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
KOKCBKAK_00433 2.4e-56 S ABC-2 type transporter
KOKCBKAK_00434 4.3e-98
KOKCBKAK_00435 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KOKCBKAK_00436 1e-125 gntR1 K transcriptional
KOKCBKAK_00437 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KOKCBKAK_00438 2.9e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KOKCBKAK_00439 2.7e-86
KOKCBKAK_00440 2.3e-90 niaR S small molecule binding protein (contains 3H domain)
KOKCBKAK_00441 4e-127 K DNA-binding helix-turn-helix protein
KOKCBKAK_00442 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KOKCBKAK_00443 2.6e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOKCBKAK_00444 1.8e-162 GK ROK family
KOKCBKAK_00445 3.5e-157 dprA LU DNA protecting protein DprA
KOKCBKAK_00446 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KOKCBKAK_00447 4.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
KOKCBKAK_00448 9e-53 V ABC-2 family transporter protein
KOKCBKAK_00450 2.4e-121 KT Transcriptional regulatory protein, C terminal
KOKCBKAK_00451 2e-223 T PhoQ Sensor
KOKCBKAK_00452 1.2e-255 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KOKCBKAK_00453 6.5e-223 XK27_05470 E Methionine synthase
KOKCBKAK_00454 5.1e-69 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KOKCBKAK_00455 2.8e-252 V Glucan-binding protein C
KOKCBKAK_00456 2.1e-120 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KOKCBKAK_00457 2.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KOKCBKAK_00458 2.2e-99 S Protein of unknown function (DUF1697)
KOKCBKAK_00459 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KOKCBKAK_00460 7.7e-177 clcA_2 P Chloride transporter, ClC family
KOKCBKAK_00461 1.5e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
KOKCBKAK_00462 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KOKCBKAK_00463 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
KOKCBKAK_00465 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KOKCBKAK_00468 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KOKCBKAK_00469 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KOKCBKAK_00470 1.9e-42 C Pyridoxamine 5'-phosphate oxidase
KOKCBKAK_00471 3.1e-97 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
KOKCBKAK_00472 4.5e-79 S Macro domain
KOKCBKAK_00473 6.6e-70 mgrA K Transcriptional regulator, MarR family
KOKCBKAK_00474 7.6e-136 1.6.5.2 GM epimerase
KOKCBKAK_00475 2.2e-171 C alcohol dehydrogenase
KOKCBKAK_00476 6.6e-128 proV E abc transporter atp-binding protein
KOKCBKAK_00477 8.6e-263 proWX P ABC transporter
KOKCBKAK_00478 1.1e-107 magIII L Base excision DNA repair protein, HhH-GPD family
KOKCBKAK_00479 2e-138 S Phenazine biosynthesis protein
KOKCBKAK_00480 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
KOKCBKAK_00481 3.7e-132 cbiQ P Cobalt transport protein
KOKCBKAK_00482 3.5e-157 P abc transporter atp-binding protein
KOKCBKAK_00483 8.5e-145 cbiO2 P ABC transporter, ATP-binding protein
KOKCBKAK_00484 1.5e-112 tnp L DDE domain
KOKCBKAK_00485 2e-74 pnuC H nicotinamide mononucleotide transporter
KOKCBKAK_00486 5.9e-10
KOKCBKAK_00487 5.9e-61 S Protein of unknown function with HXXEE motif
KOKCBKAK_00488 1.4e-104 K Transcriptional regulator, TetR family
KOKCBKAK_00489 2e-150 czcD P cation diffusion facilitator family transporter
KOKCBKAK_00490 1.1e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KOKCBKAK_00491 1.5e-186 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
KOKCBKAK_00492 3.3e-42 2.4.2.3 F Phosphorylase superfamily
KOKCBKAK_00493 8.3e-111 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KOKCBKAK_00494 1.4e-150 S von Willebrand factor (vWF) type A domain
KOKCBKAK_00495 3.4e-180 yclQ P ABC-type enterochelin transport system, periplasmic component
KOKCBKAK_00496 9.6e-234 dinF V Mate efflux family protein
KOKCBKAK_00497 2.4e-273 S Psort location CytoplasmicMembrane, score
KOKCBKAK_00498 6.6e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KOKCBKAK_00499 1e-142 S TraX protein
KOKCBKAK_00500 6.1e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KOKCBKAK_00501 5.9e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KOKCBKAK_00502 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KOKCBKAK_00503 4.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KOKCBKAK_00504 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOKCBKAK_00505 2.6e-240 nylA 3.5.1.4 J Belongs to the amidase family
KOKCBKAK_00506 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
KOKCBKAK_00507 6.4e-82 yecS P ABC transporter (Permease
KOKCBKAK_00508 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KOKCBKAK_00509 1.1e-169 bglC K Transcriptional regulator
KOKCBKAK_00510 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KOKCBKAK_00511 2.4e-240 agcS E (Alanine) symporter
KOKCBKAK_00512 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KOKCBKAK_00513 4.3e-239 metY 2.5.1.49 E o-acetylhomoserine
KOKCBKAK_00514 2.9e-27 S haloacid dehalogenase-like hydrolase
KOKCBKAK_00515 8.7e-60 S haloacid dehalogenase-like hydrolase
KOKCBKAK_00516 8.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KOKCBKAK_00517 1.3e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KOKCBKAK_00518 4.7e-35 M1-755 S Domain of unknown function (DUF1858)
KOKCBKAK_00519 6.9e-248 XK27_04775 S hemerythrin HHE cation binding domain
KOKCBKAK_00520 3.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KOKCBKAK_00521 6.4e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KOKCBKAK_00522 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KOKCBKAK_00523 3e-44 yktA S Belongs to the UPF0223 family
KOKCBKAK_00524 6.5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KOKCBKAK_00525 2.9e-251 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KOKCBKAK_00526 3.4e-155 pstS P phosphate
KOKCBKAK_00527 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KOKCBKAK_00528 7.7e-155 pstA P phosphate transport system permease
KOKCBKAK_00529 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOKCBKAK_00530 4.6e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOKCBKAK_00531 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
KOKCBKAK_00532 0.0 pepN 3.4.11.2 E aminopeptidase
KOKCBKAK_00533 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KOKCBKAK_00534 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
KOKCBKAK_00535 1e-39
KOKCBKAK_00536 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOKCBKAK_00537 1.2e-301 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KOKCBKAK_00538 8.7e-171 malR K Transcriptional regulator
KOKCBKAK_00539 2.5e-228 malX G ABC transporter
KOKCBKAK_00540 9.7e-250 malF P ABC transporter (Permease
KOKCBKAK_00541 9.8e-152 malG P ABC transporter (Permease
KOKCBKAK_00542 3.3e-211 msmX P Belongs to the ABC transporter superfamily
KOKCBKAK_00543 1e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KOKCBKAK_00544 9.3e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KOKCBKAK_00545 1.7e-288 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KOKCBKAK_00546 7.6e-230 ycdB P peroxidase
KOKCBKAK_00547 2.4e-145 ycdO P periplasmic lipoprotein involved in iron transport
KOKCBKAK_00548 7.6e-178 fatB P ABC-type enterochelin transport system, periplasmic component
KOKCBKAK_00549 1.2e-135 yclP 3.6.3.34 P abc transporter atp-binding protein
KOKCBKAK_00550 1.2e-156 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOKCBKAK_00551 1.8e-128 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOKCBKAK_00552 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KOKCBKAK_00553 3.2e-84 lytC 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KOKCBKAK_00554 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KOKCBKAK_00555 8e-38 L Transposase
KOKCBKAK_00556 4.8e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOKCBKAK_00557 5.1e-104 wecD M Acetyltransferase (GNAT) domain
KOKCBKAK_00558 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KOKCBKAK_00559 5.7e-158 GK ROK family
KOKCBKAK_00560 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
KOKCBKAK_00561 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
KOKCBKAK_00563 7.4e-80 hmpT S cog cog4720
KOKCBKAK_00564 2.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KOKCBKAK_00565 2e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KOKCBKAK_00566 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KOKCBKAK_00567 1.7e-103 thiJ-2 3.5.1.124 S DJ-1/PfpI family
KOKCBKAK_00568 1.8e-299 dnaK O Heat shock 70 kDa protein
KOKCBKAK_00569 8.8e-66 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KOKCBKAK_00570 1.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KOKCBKAK_00571 1.2e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
KOKCBKAK_00572 6.7e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KOKCBKAK_00573 5.6e-132 ais G Phosphoglycerate mutase
KOKCBKAK_00574 2.3e-243 XK27_08635 S UPF0210 protein
KOKCBKAK_00575 1e-38 gcvR T UPF0237 protein
KOKCBKAK_00576 1.4e-231 capA M Bacterial capsule synthesis protein
KOKCBKAK_00577 8.5e-140 srtB 3.4.22.70 S sortase, SrtB family
KOKCBKAK_00578 1.3e-84
KOKCBKAK_00579 1.5e-29 K Helix-turn-helix domain
KOKCBKAK_00580 2.9e-17
KOKCBKAK_00581 4.5e-55 cadC K Bacterial regulatory protein, arsR family
KOKCBKAK_00582 1.2e-101 cadD P cadmium resistance
KOKCBKAK_00584 6.7e-89 H Methyltransferase
KOKCBKAK_00585 1.7e-89 S Protein conserved in bacteria
KOKCBKAK_00586 4.4e-55 K HxlR-like helix-turn-helix
KOKCBKAK_00587 3.9e-162 S Pseudomonas avirulence D protein (AvrD)
KOKCBKAK_00588 1.7e-122 cmk 2.7.4.25, 5.3.1.12 F AAA domain
KOKCBKAK_00589 2.9e-204 C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KOKCBKAK_00590 2.8e-236 mmr P Major Facilitator Superfamily
KOKCBKAK_00592 2.4e-80 K DNA-binding helix-turn-helix protein
KOKCBKAK_00593 2.1e-07
KOKCBKAK_00594 2.6e-36
KOKCBKAK_00595 7.5e-194 L Replication initiation factor
KOKCBKAK_00596 1.6e-39 L Helix-turn-helix domain
KOKCBKAK_00597 1.2e-222 int2 L Phage integrase family
KOKCBKAK_00598 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KOKCBKAK_00599 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KOKCBKAK_00600 5.1e-22 K Transcriptional
KOKCBKAK_00602 4.1e-153 degV S DegV family
KOKCBKAK_00603 2.7e-91 yacP S RNA-binding protein containing a PIN domain
KOKCBKAK_00604 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOKCBKAK_00606 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KOKCBKAK_00607 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOKCBKAK_00609 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
KOKCBKAK_00610 1e-139 S SseB protein N-terminal domain
KOKCBKAK_00611 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KOKCBKAK_00612 1.1e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KOKCBKAK_00613 4.5e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KOKCBKAK_00614 0.0 clpC O Belongs to the ClpA ClpB family
KOKCBKAK_00615 4.8e-76 ctsR K Belongs to the CtsR family
KOKCBKAK_00616 1.2e-82 S Putative small multi-drug export protein
KOKCBKAK_00617 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KOKCBKAK_00618 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
KOKCBKAK_00619 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
KOKCBKAK_00620 2.3e-287 ahpF O alkyl hydroperoxide reductase
KOKCBKAK_00622 3.2e-95 S reductase
KOKCBKAK_00623 3.9e-72 badR K Transcriptional regulator, marr family
KOKCBKAK_00624 5.1e-34 XK27_02060 S Transglycosylase associated protein
KOKCBKAK_00625 4.3e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KOKCBKAK_00626 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOKCBKAK_00631 1.9e-07
KOKCBKAK_00634 2.6e-10
KOKCBKAK_00640 5.4e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KOKCBKAK_00641 4.9e-60 arsC 1.20.4.1 P Belongs to the ArsC family
KOKCBKAK_00643 1e-186 femA 2.3.2.10, 2.3.2.16 V FemAB family
KOKCBKAK_00644 5.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOKCBKAK_00645 3.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
KOKCBKAK_00646 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KOKCBKAK_00647 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOKCBKAK_00648 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KOKCBKAK_00649 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KOKCBKAK_00650 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KOKCBKAK_00651 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KOKCBKAK_00652 5.1e-216 ftsW D Belongs to the SEDS family
KOKCBKAK_00653 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KOKCBKAK_00654 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KOKCBKAK_00655 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KOKCBKAK_00657 1.9e-86 L Transposase
KOKCBKAK_00659 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KOKCBKAK_00660 7.7e-83 comFC K competence protein
KOKCBKAK_00661 2.7e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KOKCBKAK_00662 9.1e-110 yvyE 3.4.13.9 S YigZ family
KOKCBKAK_00663 1.4e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KOKCBKAK_00664 7.1e-113 acuB S CBS domain
KOKCBKAK_00665 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KOKCBKAK_00666 2.4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KOKCBKAK_00667 8.3e-139 livM E Belongs to the binding-protein-dependent transport system permease family
KOKCBKAK_00668 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KOKCBKAK_00669 3.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KOKCBKAK_00670 5.4e-46 ylbG S UPF0298 protein
KOKCBKAK_00671 1.5e-74 ylbF S Belongs to the UPF0342 family
KOKCBKAK_00672 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOKCBKAK_00673 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KOKCBKAK_00674 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KOKCBKAK_00675 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
KOKCBKAK_00676 4.3e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KOKCBKAK_00677 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
KOKCBKAK_00678 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KOKCBKAK_00679 2.2e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KOKCBKAK_00680 4.9e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOKCBKAK_00681 1.3e-99 yvdD 3.2.2.10 S Belongs to the LOG family
KOKCBKAK_00682 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KOKCBKAK_00683 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KOKCBKAK_00684 8e-42 ylxQ J ribosomal protein
KOKCBKAK_00685 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KOKCBKAK_00686 2.4e-196 nusA K Participates in both transcription termination and antitermination
KOKCBKAK_00687 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
KOKCBKAK_00688 1.8e-210 brpA K Transcriptional
KOKCBKAK_00689 6e-91 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
KOKCBKAK_00690 4.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KOKCBKAK_00691 2.1e-247 pbuO S permease
KOKCBKAK_00692 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KOKCBKAK_00693 3.2e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KOKCBKAK_00694 6.2e-169 manL 2.7.1.191 G pts system
KOKCBKAK_00695 5.7e-133 manY G pts system
KOKCBKAK_00696 3.4e-158 manN G PTS system mannose fructose sorbose family IID component
KOKCBKAK_00697 2e-67 manO S Protein conserved in bacteria
KOKCBKAK_00698 4.9e-174 manL 2.7.1.191 G pts system
KOKCBKAK_00699 1.7e-116 manM G pts system
KOKCBKAK_00700 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
KOKCBKAK_00701 2.7e-61 manO S protein conserved in bacteria
KOKCBKAK_00702 2e-228 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KOKCBKAK_00703 1.4e-105
KOKCBKAK_00704 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KOKCBKAK_00705 4.4e-166 dnaI L Primosomal protein DnaI
KOKCBKAK_00706 6.7e-215 dnaB L Replication initiation and membrane attachment
KOKCBKAK_00707 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KOKCBKAK_00708 9.8e-283 T PhoQ Sensor
KOKCBKAK_00709 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOKCBKAK_00710 1.2e-89 yceD K metal-binding, possibly nucleic acid-binding protein
KOKCBKAK_00711 1.3e-128 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KOKCBKAK_00712 7.2e-237 P COG0168 Trk-type K transport systems, membrane components
KOKCBKAK_00713 6.1e-120 ktrA P COG0569 K transport systems, NAD-binding component
KOKCBKAK_00714 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KOKCBKAK_00715 1.2e-99 metI P ABC transporter (Permease
KOKCBKAK_00716 2e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOKCBKAK_00717 3.5e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KOKCBKAK_00718 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
KOKCBKAK_00719 1.8e-137 ET ABC transporter substrate-binding protein
KOKCBKAK_00720 1e-128 cbiO P ABC transporter
KOKCBKAK_00721 1.1e-136 P cobalt transport protein
KOKCBKAK_00722 1.3e-176 cbiM P biosynthesis protein CbiM
KOKCBKAK_00723 5.2e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KOKCBKAK_00724 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KOKCBKAK_00725 1.2e-129 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KOKCBKAK_00726 3.9e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KOKCBKAK_00727 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KOKCBKAK_00728 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KOKCBKAK_00729 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KOKCBKAK_00730 6.8e-95 ureI S AmiS/UreI family transporter
KOKCBKAK_00731 1.6e-38 S Domain of unknown function (DUF4173)
KOKCBKAK_00732 6.4e-54 yhaI L Membrane
KOKCBKAK_00733 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KOKCBKAK_00734 3e-154 K sequence-specific DNA binding
KOKCBKAK_00735 1.9e-88 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_00736 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KOKCBKAK_00737 1e-99 thiT S Thiamine transporter
KOKCBKAK_00738 3.3e-62 yjqA S Bacterial PH domain
KOKCBKAK_00739 1.6e-152 corA P CorA-like protein
KOKCBKAK_00740 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KOKCBKAK_00741 7e-43 yazA L endonuclease containing a URI domain
KOKCBKAK_00742 5.5e-141 yabB 2.1.1.223 L Methyltransferase
KOKCBKAK_00743 1.3e-149 nodB3 G deacetylase
KOKCBKAK_00744 1.9e-141 plsC 2.3.1.51 I Acyltransferase
KOKCBKAK_00745 1.2e-94 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KOKCBKAK_00746 0.0 comEC S Competence protein ComEC
KOKCBKAK_00747 2.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOKCBKAK_00748 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KOKCBKAK_00749 3e-232 ytoI K transcriptional regulator containing CBS domains
KOKCBKAK_00750 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KOKCBKAK_00751 3.7e-163 rbn E Belongs to the UPF0761 family
KOKCBKAK_00752 8.2e-85 ccl S cog cog4708
KOKCBKAK_00753 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KOKCBKAK_00754 2.1e-185 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KOKCBKAK_00756 2.7e-172 yfjR K regulation of single-species biofilm formation
KOKCBKAK_00758 9.8e-72 S QueT transporter
KOKCBKAK_00759 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
KOKCBKAK_00761 1.3e-198 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOKCBKAK_00762 2.9e-17 yjdB S Domain of unknown function (DUF4767)
KOKCBKAK_00763 5.1e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KOKCBKAK_00764 2.8e-190 O protein import
KOKCBKAK_00765 2.7e-129 agrA KT phosphorelay signal transduction system
KOKCBKAK_00766 7.8e-198 2.7.13.3 T GHKL domain
KOKCBKAK_00768 1.9e-88 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_00769 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KOKCBKAK_00770 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KOKCBKAK_00771 1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KOKCBKAK_00772 5.7e-179 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
KOKCBKAK_00773 2.2e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KOKCBKAK_00774 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOKCBKAK_00775 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
KOKCBKAK_00776 5.7e-291 S Protein of unknown function (DUF3114)
KOKCBKAK_00778 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KOKCBKAK_00779 3.6e-297 V abc transporter atp-binding protein
KOKCBKAK_00780 0.0 V abc transporter atp-binding protein
KOKCBKAK_00781 6.7e-191 XK27_10075 S abc transporter atp-binding protein
KOKCBKAK_00782 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
KOKCBKAK_00783 0.0 M Pilin isopeptide linkage domain protein
KOKCBKAK_00784 0.0 zmpB M signal peptide protein, YSIRK family
KOKCBKAK_00785 0.0 GM domain, Protein
KOKCBKAK_00786 7.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KOKCBKAK_00787 0.0 sbcC L ATPase involved in DNA repair
KOKCBKAK_00788 6.9e-09
KOKCBKAK_00790 3.4e-155 cat 2.3.1.28 S acetyltransferase'
KOKCBKAK_00791 0.0 M family 8
KOKCBKAK_00792 9e-148 epsH S acetyltransferase'
KOKCBKAK_00793 2e-238 M Glycosyltransferase, family 8
KOKCBKAK_00794 1.2e-288 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KOKCBKAK_00795 2.3e-197 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KOKCBKAK_00796 1.4e-184 nss M transferase activity, transferring glycosyl groups
KOKCBKAK_00797 9.3e-236 M Glycosyltransferase, family 8
KOKCBKAK_00798 1.3e-167 cpsJ M Glycosyltransferase group 2 family protein
KOKCBKAK_00799 0.0 M cog cog1442
KOKCBKAK_00800 3.1e-242 M family 8
KOKCBKAK_00801 3.3e-164 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
KOKCBKAK_00802 5.6e-310 asp1 S Accessory Sec system protein Asp1
KOKCBKAK_00803 4.2e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
KOKCBKAK_00804 1.4e-67 asp3 S Accessory Sec system protein Asp3
KOKCBKAK_00805 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOKCBKAK_00806 1.1e-12 S Accessory secretory protein Sec Asp4
KOKCBKAK_00807 7e-12 S Accessory secretory protein Sec, Asp5
KOKCBKAK_00812 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_00813 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_00815 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KOKCBKAK_00816 3.5e-214 XK27_05110 P Chloride transporter ClC family
KOKCBKAK_00817 2.6e-29 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KOKCBKAK_00818 1.6e-280 clcA P Chloride transporter, ClC family
KOKCBKAK_00819 1e-75 fld C Flavodoxin
KOKCBKAK_00820 9.8e-19 XK27_08880
KOKCBKAK_00821 1.8e-125 XK27_08875 O Zinc-dependent metalloprotease
KOKCBKAK_00822 4e-147 estA CE1 S Esterase
KOKCBKAK_00823 2.1e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOKCBKAK_00824 3.1e-136 XK27_08845 S abc transporter atp-binding protein
KOKCBKAK_00825 3.4e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KOKCBKAK_00826 1.1e-176 XK27_08835 S ABC transporter substrate binding protein
KOKCBKAK_00827 3.8e-18 S Domain of unknown function (DUF4649)
KOKCBKAK_00828 4.8e-31 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_00829 2.8e-57 L Integrase
KOKCBKAK_00830 1.1e-57 L Integrase
KOKCBKAK_00831 1.8e-47 L Transposase IS116 IS110 IS902
KOKCBKAK_00832 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KOKCBKAK_00833 4.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KOKCBKAK_00834 0.0 dnaE 2.7.7.7 L DNA polymerase
KOKCBKAK_00835 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOKCBKAK_00836 5.6e-277 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOKCBKAK_00837 3.5e-37 ysdA L Membrane
KOKCBKAK_00838 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KOKCBKAK_00839 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KOKCBKAK_00840 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOKCBKAK_00841 6.2e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KOKCBKAK_00843 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KOKCBKAK_00844 6.2e-97 ypmS S Protein conserved in bacteria
KOKCBKAK_00845 2.2e-162 ypmR E COG2755 Lysophospholipase L1 and related esterases
KOKCBKAK_00846 9.3e-150 DegV S DegV family
KOKCBKAK_00847 4.6e-302 recN L May be involved in recombinational repair of damaged DNA
KOKCBKAK_00848 8.3e-73 argR K Regulates arginine biosynthesis genes
KOKCBKAK_00849 4.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KOKCBKAK_00850 1.7e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KOKCBKAK_00851 3.5e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOKCBKAK_00852 4.6e-236 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOKCBKAK_00854 2.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KOKCBKAK_00855 1.3e-125 dnaD
KOKCBKAK_00856 1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KOKCBKAK_00857 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KOKCBKAK_00858 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KOKCBKAK_00859 1.8e-66 GnaT 2.5.1.16 K acetyltransferase
KOKCBKAK_00860 1.1e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KOKCBKAK_00861 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KOKCBKAK_00862 1.2e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KOKCBKAK_00863 1.1e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KOKCBKAK_00864 3.2e-227 rodA D Belongs to the SEDS family
KOKCBKAK_00865 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KOKCBKAK_00866 8e-38 L Transposase
KOKCBKAK_00867 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KOKCBKAK_00868 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KOKCBKAK_00869 8e-180 XK27_08075 M glycosyl transferase family 2
KOKCBKAK_00870 3.5e-84 S Carbohydrate-binding domain-containing protein Cthe_2159
KOKCBKAK_00871 1.3e-145 P molecular chaperone
KOKCBKAK_00872 5.5e-92 XK27_05505 S Psort location CytoplasmicMembrane, score
KOKCBKAK_00875 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
KOKCBKAK_00876 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KOKCBKAK_00877 3.6e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KOKCBKAK_00878 2.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KOKCBKAK_00879 4.7e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KOKCBKAK_00880 9.7e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KOKCBKAK_00881 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KOKCBKAK_00882 3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KOKCBKAK_00883 1.8e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KOKCBKAK_00884 5.9e-194 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KOKCBKAK_00885 1.1e-60 XK27_08085
KOKCBKAK_00886 2.8e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KOKCBKAK_00887 1e-139 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KOKCBKAK_00888 6.5e-119 ylfI S tigr01906
KOKCBKAK_00889 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KOKCBKAK_00890 1.3e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
KOKCBKAK_00891 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
KOKCBKAK_00892 2.9e-30 KT response to antibiotic
KOKCBKAK_00894 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KOKCBKAK_00895 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KOKCBKAK_00896 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KOKCBKAK_00897 4.3e-258 S phospholipase Carboxylesterase
KOKCBKAK_00898 1.1e-200 yurR 1.4.5.1 E oxidoreductase
KOKCBKAK_00899 1.4e-145 zupT P Mediates zinc uptake. May also transport other divalent cations
KOKCBKAK_00900 9.3e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KOKCBKAK_00901 2.6e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
KOKCBKAK_00902 1.8e-66 gtrA S GtrA-like protein
KOKCBKAK_00903 9.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KOKCBKAK_00904 8.6e-168 ybbR S Protein conserved in bacteria
KOKCBKAK_00905 2e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KOKCBKAK_00906 1.2e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KOKCBKAK_00907 2.3e-150 cobQ S glutamine amidotransferase
KOKCBKAK_00908 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KOKCBKAK_00909 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
KOKCBKAK_00910 1.6e-39 MA20_06245 S yiaA/B two helix domain
KOKCBKAK_00911 0.0 uup S abc transporter atp-binding protein
KOKCBKAK_00912 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KOKCBKAK_00913 3.2e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
KOKCBKAK_00914 3.8e-226 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
KOKCBKAK_00915 2.7e-153 XK27_05675 S Esterase
KOKCBKAK_00916 2.3e-161 XK27_05670 S Putative esterase
KOKCBKAK_00917 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KOKCBKAK_00918 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KOKCBKAK_00919 3e-38 ptsH G phosphocarrier protein Hpr
KOKCBKAK_00920 3.9e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
KOKCBKAK_00921 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
KOKCBKAK_00922 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KOKCBKAK_00923 2.9e-34 nrdH O Glutaredoxin
KOKCBKAK_00924 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOKCBKAK_00925 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOKCBKAK_00926 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KOKCBKAK_00927 8.4e-138 divIVA D Cell division initiation protein
KOKCBKAK_00928 5e-145 ylmH S conserved protein, contains S4-like domain
KOKCBKAK_00929 6.5e-30 yggT D integral membrane protein
KOKCBKAK_00930 3.2e-101 sepF D cell septum assembly
KOKCBKAK_00931 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KOKCBKAK_00932 1.7e-238 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KOKCBKAK_00933 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KOKCBKAK_00934 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KOKCBKAK_00935 1.6e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KOKCBKAK_00936 1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KOKCBKAK_00938 0.0 typA T GTP-binding protein TypA
KOKCBKAK_00939 3.5e-177 glk 2.7.1.2 G Glucokinase
KOKCBKAK_00940 2.4e-27 yqgQ S protein conserved in bacteria
KOKCBKAK_00941 5.2e-83 perR P Belongs to the Fur family
KOKCBKAK_00942 9.3e-92 dps P Belongs to the Dps family
KOKCBKAK_00943 7.5e-115 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KOKCBKAK_00944 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KOKCBKAK_00945 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KOKCBKAK_00946 1.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
KOKCBKAK_00947 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KOKCBKAK_00948 4.8e-64 S Domain of unknown function (DUF4430)
KOKCBKAK_00949 6.7e-73 S Psort location CytoplasmicMembrane, score
KOKCBKAK_00950 6e-129 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
KOKCBKAK_00951 2.1e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
KOKCBKAK_00952 3.9e-165 sitA P Belongs to the bacterial solute-binding protein 9 family
KOKCBKAK_00953 4.8e-114 sirR K iron dependent repressor
KOKCBKAK_00954 9.9e-134 htpX O Belongs to the peptidase M48B family
KOKCBKAK_00955 7.7e-92 lemA S LemA family
KOKCBKAK_00956 5.1e-171 spd F DNA RNA non-specific endonuclease
KOKCBKAK_00957 0.0 2.4.1.21 GT5 M Right handed beta helix region
KOKCBKAK_00958 6e-68 S double-stranded DNA endodeoxyribonuclease activity
KOKCBKAK_00959 1.4e-303 hsdM 2.1.1.72 V type I restriction-modification system
KOKCBKAK_00960 4.8e-74 S Protein conserved in bacteria
KOKCBKAK_00961 4.9e-87
KOKCBKAK_00962 5e-77
KOKCBKAK_00963 3.3e-108 3.1.21.3 V Type I restriction modification DNA specificity domain
KOKCBKAK_00964 3.7e-117 S Bacteriophage abortive infection AbiH
KOKCBKAK_00965 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KOKCBKAK_00966 1.1e-44 K Helix-turn-helix domain
KOKCBKAK_00967 9.9e-45 S Phage derived protein Gp49-like (DUF891)
KOKCBKAK_00968 2.7e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KOKCBKAK_00969 8.4e-210 MA20_36090 S Protein of unknown function (DUF2974)
KOKCBKAK_00970 2.8e-111 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOKCBKAK_00971 1.6e-157 5.2.1.8 G hydrolase
KOKCBKAK_00972 5.3e-27 P Hemerythrin HHE cation binding domain protein
KOKCBKAK_00973 3.8e-141 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
KOKCBKAK_00974 6.1e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KOKCBKAK_00975 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KOKCBKAK_00976 5.2e-175 S hydrolase
KOKCBKAK_00977 8.4e-23
KOKCBKAK_00978 6.7e-152 M LysM domain
KOKCBKAK_00979 8.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KOKCBKAK_00980 3.8e-11
KOKCBKAK_00981 3.6e-180 dapB 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
KOKCBKAK_00982 9.4e-97 K MerR, DNA binding
KOKCBKAK_00983 0.0 L helicase
KOKCBKAK_00984 6.8e-63 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
KOKCBKAK_00985 2.1e-11
KOKCBKAK_00986 6.6e-235 mntH P H( )-stimulated, divalent metal cation uptake system
KOKCBKAK_00987 1.4e-33 XK27_12190 S protein conserved in bacteria
KOKCBKAK_00989 3.2e-87 bioY S biotin synthase
KOKCBKAK_00990 7.5e-252 yegQ O Peptidase U32
KOKCBKAK_00991 2e-177 yegQ O Peptidase U32
KOKCBKAK_00993 4.2e-69 ytxH S General stress protein
KOKCBKAK_00994 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KOKCBKAK_00995 6.2e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KOKCBKAK_00996 2e-166 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KOKCBKAK_00997 2.2e-41 pspC KT PspC domain
KOKCBKAK_00998 0.0 yhgF K Transcriptional accessory protein
KOKCBKAK_01000 4.6e-155 XK27_03015 S permease
KOKCBKAK_01001 2.9e-148 ycgQ S TIGR03943 family
KOKCBKAK_01002 1.1e-287 sulP P Sulfate permease and related transporters (MFS superfamily)
KOKCBKAK_01003 5.2e-102
KOKCBKAK_01004 1.4e-118 estA E GDSL-like Lipase/Acylhydrolase
KOKCBKAK_01005 4.7e-95 S CAAX protease self-immunity
KOKCBKAK_01006 9.4e-51
KOKCBKAK_01008 5.2e-65 yqeB S Pyrimidine dimer DNA glycosylase
KOKCBKAK_01009 2.7e-59 S Protein of unknown function (DUF1722)
KOKCBKAK_01010 1.7e-19 S Bacterial lipoprotein
KOKCBKAK_01011 6.8e-11
KOKCBKAK_01012 8.6e-123 V CAAX protease self-immunity
KOKCBKAK_01013 6.4e-48
KOKCBKAK_01014 1.6e-32 K Transcriptional regulator
KOKCBKAK_01015 8e-24 K TetR family transcriptional regulator
KOKCBKAK_01016 2.9e-81 Q Methyltransferase domain
KOKCBKAK_01017 2.1e-131 ybbA S Putative esterase
KOKCBKAK_01018 4.7e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KOKCBKAK_01019 1.1e-136 fecE 3.6.3.34 HP ABC transporter
KOKCBKAK_01020 4.8e-156 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOKCBKAK_01021 9.2e-125 V CAAX protease self-immunity
KOKCBKAK_01022 1.1e-155 S Domain of unknown function (DUF4300)
KOKCBKAK_01023 1.9e-95 tetR K transcriptional regulator
KOKCBKAK_01024 3.5e-292 norB P Major facilitator superfamily
KOKCBKAK_01025 1.6e-255 L Transposase
KOKCBKAK_01026 0.0 M family 8
KOKCBKAK_01027 8.6e-108 cutC P Participates in the control of copper homeostasis
KOKCBKAK_01028 3.6e-130 S CAAX amino terminal protease family
KOKCBKAK_01029 2.8e-97 ypgQ F HD superfamily hydrolase
KOKCBKAK_01030 3e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
KOKCBKAK_01031 2.1e-149 yitS S EDD domain protein, DegV family
KOKCBKAK_01032 8.2e-205 yeaN P transporter
KOKCBKAK_01033 5.2e-44 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KOKCBKAK_01034 7.4e-158 K DNA-binding helix-turn-helix protein
KOKCBKAK_01035 1.5e-138 S CAAX protease self-immunity
KOKCBKAK_01036 7.9e-76 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
KOKCBKAK_01037 6.5e-142 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KOKCBKAK_01038 6.9e-96 S HD domain
KOKCBKAK_01039 6.7e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOKCBKAK_01040 5.9e-97 mip S hydroperoxide reductase activity
KOKCBKAK_01041 4e-198 I acyl-CoA dehydrogenase
KOKCBKAK_01042 8.4e-152 ydiA P C4-dicarboxylate transporter malic acid transport protein
KOKCBKAK_01043 1.3e-241 msrR K Transcriptional regulator
KOKCBKAK_01044 1.1e-152 pheA 4.2.1.51 E Prephenate dehydratase
KOKCBKAK_01045 6.7e-76 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KOKCBKAK_01046 1.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KOKCBKAK_01047 2.9e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KOKCBKAK_01048 4.2e-53 yheA S Belongs to the UPF0342 family
KOKCBKAK_01049 3.5e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KOKCBKAK_01050 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KOKCBKAK_01051 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KOKCBKAK_01052 9.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KOKCBKAK_01053 4.4e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KOKCBKAK_01054 2.7e-216 ywbD 2.1.1.191 J Methyltransferase
KOKCBKAK_01055 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KOKCBKAK_01056 1.2e-25 WQ51_00785
KOKCBKAK_01057 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KOKCBKAK_01058 4.3e-77 yueI S Protein of unknown function (DUF1694)
KOKCBKAK_01059 1.4e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KOKCBKAK_01060 2.3e-188 yyaQ S YjbR
KOKCBKAK_01061 1.9e-181 ccpA K Catabolite control protein A
KOKCBKAK_01062 6e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KOKCBKAK_01063 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KOKCBKAK_01064 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOKCBKAK_01065 2.5e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KOKCBKAK_01066 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KOKCBKAK_01067 2e-33 secG U Preprotein translocase subunit SecG
KOKCBKAK_01068 6.5e-221 mdtG EGP Major facilitator Superfamily
KOKCBKAK_01069 8.6e-102 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KOKCBKAK_01070 1.4e-150 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KOKCBKAK_01071 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KOKCBKAK_01072 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KOKCBKAK_01073 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KOKCBKAK_01074 2.1e-149 licT K antiterminator
KOKCBKAK_01075 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KOKCBKAK_01076 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KOKCBKAK_01077 6.6e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KOKCBKAK_01078 4.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KOKCBKAK_01079 2.9e-150 I Alpha/beta hydrolase family
KOKCBKAK_01080 6.6e-08
KOKCBKAK_01081 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KOKCBKAK_01082 1.4e-78 feoA P FeoA domain protein
KOKCBKAK_01083 1.3e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOKCBKAK_01084 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KOKCBKAK_01085 1e-34 ykuJ S protein conserved in bacteria
KOKCBKAK_01086 3.7e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KOKCBKAK_01087 0.0 clpE O Belongs to the ClpA ClpB family
KOKCBKAK_01088 3e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KOKCBKAK_01089 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
KOKCBKAK_01090 4.6e-177 S oxidoreductase
KOKCBKAK_01091 2.9e-117 M Pfam SNARE associated Golgi protein
KOKCBKAK_01092 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
KOKCBKAK_01095 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
KOKCBKAK_01098 4.8e-16 S Protein of unknown function (DUF2969)
KOKCBKAK_01099 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KOKCBKAK_01100 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOKCBKAK_01101 2.5e-10
KOKCBKAK_01103 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOKCBKAK_01104 1.8e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KOKCBKAK_01105 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
KOKCBKAK_01106 2.2e-30 S Domain of unknown function (DUF1912)
KOKCBKAK_01107 1.1e-178 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KOKCBKAK_01108 2.3e-251 mmuP E amino acid
KOKCBKAK_01109 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KOKCBKAK_01110 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KOKCBKAK_01111 9.7e-22
KOKCBKAK_01112 4.9e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KOKCBKAK_01113 3.8e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KOKCBKAK_01114 2.3e-215 mvaS 2.3.3.10 I synthase
KOKCBKAK_01115 4.7e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KOKCBKAK_01116 3e-78 K hmm pf08876
KOKCBKAK_01117 1.2e-118 yqfA K protein, Hemolysin III
KOKCBKAK_01118 4.1e-29 pspC KT PspC domain protein
KOKCBKAK_01119 5.7e-205 S Protein of unknown function (DUF3114)
KOKCBKAK_01120 1.8e-170 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KOKCBKAK_01121 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KOKCBKAK_01122 2.2e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KOKCBKAK_01123 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KOKCBKAK_01124 0.0 U protein secretion
KOKCBKAK_01125 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KOKCBKAK_01126 2.9e-25
KOKCBKAK_01127 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KOKCBKAK_01128 8.4e-249 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KOKCBKAK_01129 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KOKCBKAK_01131 1.7e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KOKCBKAK_01132 2e-175 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KOKCBKAK_01133 4.8e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KOKCBKAK_01134 1e-154 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KOKCBKAK_01135 4.4e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KOKCBKAK_01136 8.2e-140 E Alpha beta hydrolase
KOKCBKAK_01138 5.8e-101 O stage V sporulation protein K
KOKCBKAK_01139 1.1e-88
KOKCBKAK_01140 1.2e-21
KOKCBKAK_01141 1.2e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KOKCBKAK_01142 1.9e-214 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KOKCBKAK_01143 2.7e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOKCBKAK_01144 3.9e-114 S VIT family
KOKCBKAK_01145 1e-126 deoD_1 2.4.2.3 F Phosphorylase superfamily
KOKCBKAK_01146 8.4e-26
KOKCBKAK_01147 1e-27 XK27_00085 K Transcriptional
KOKCBKAK_01148 1.8e-197 yceA S Belongs to the UPF0176 family
KOKCBKAK_01149 1.2e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOKCBKAK_01150 6.6e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KOKCBKAK_01151 0.0 lmrA V abc transporter atp-binding protein
KOKCBKAK_01152 0.0 mdlB V abc transporter atp-binding protein
KOKCBKAK_01153 2e-48 doc S Fic/DOC family
KOKCBKAK_01154 5.5e-29 S Antitoxin component of a toxin-antitoxin (TA) module
KOKCBKAK_01155 1.1e-206 L Transposase
KOKCBKAK_01156 4.6e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KOKCBKAK_01157 1.6e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KOKCBKAK_01158 3.6e-203 V permease protein
KOKCBKAK_01159 3.1e-122 macB V ABC transporter, ATP-binding protein
KOKCBKAK_01160 1.5e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KOKCBKAK_01161 2.3e-128 2.1.1.223 S Putative SAM-dependent methyltransferase
KOKCBKAK_01162 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KOKCBKAK_01163 2.7e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KOKCBKAK_01164 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KOKCBKAK_01165 1.6e-222 pyrP F uracil Permease
KOKCBKAK_01166 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KOKCBKAK_01167 7.2e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOKCBKAK_01168 5.7e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KOKCBKAK_01169 2.6e-166 fhuR K transcriptional regulator (lysR family)
KOKCBKAK_01171 2.3e-43
KOKCBKAK_01172 5.8e-69 K Helix-turn-helix
KOKCBKAK_01174 1.3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOKCBKAK_01175 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KOKCBKAK_01176 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
KOKCBKAK_01177 8.7e-254 cycA E permease
KOKCBKAK_01178 5e-38 ynzC S UPF0291 protein
KOKCBKAK_01179 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KOKCBKAK_01180 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KOKCBKAK_01181 2.1e-219 S membrane
KOKCBKAK_01182 3.7e-210 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KOKCBKAK_01183 3.5e-294 nptA P COG1283 Na phosphate symporter
KOKCBKAK_01184 4e-113 3.4.17.14, 3.5.1.28 NU amidase activity
KOKCBKAK_01185 3.6e-83 S Bacterial inner membrane protein
KOKCBKAK_01186 1.6e-143 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KOKCBKAK_01187 1.6e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
KOKCBKAK_01188 1.9e-53 glnB K Belongs to the P(II) protein family
KOKCBKAK_01189 2.5e-228 amt P Ammonium Transporter
KOKCBKAK_01190 1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KOKCBKAK_01191 1.2e-54 yabA L Involved in initiation control of chromosome replication
KOKCBKAK_01192 7.5e-133 yaaT S stage 0 sporulation protein
KOKCBKAK_01193 1.3e-159 holB 2.7.7.7 L dna polymerase iii
KOKCBKAK_01194 2.4e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KOKCBKAK_01195 1.9e-88 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_01196 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KOKCBKAK_01197 2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KOKCBKAK_01198 1.5e-97 V CAAX protease self-immunity
KOKCBKAK_01199 3.2e-141 cppA E CppA N-terminal
KOKCBKAK_01200 4.8e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KOKCBKAK_01202 4.8e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOKCBKAK_01203 4.7e-148 cah 4.2.1.1 P carbonic anhydrase
KOKCBKAK_01204 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
KOKCBKAK_01206 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KOKCBKAK_01207 9.5e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOKCBKAK_01208 2.8e-35
KOKCBKAK_01209 2.6e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KOKCBKAK_01210 5.2e-162 yxeN P ABC transporter (Permease
KOKCBKAK_01211 1.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
KOKCBKAK_01212 6.5e-10 S Protein of unknown function (DUF4059)
KOKCBKAK_01213 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KOKCBKAK_01214 1.2e-103 rsmD 2.1.1.171 L Methyltransferase
KOKCBKAK_01215 1.1e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KOKCBKAK_01216 4.2e-187 ylbL T Belongs to the peptidase S16 family
KOKCBKAK_01217 5.4e-183 yhcC S radical SAM protein
KOKCBKAK_01218 7.7e-97 ytqB J (SAM)-dependent
KOKCBKAK_01220 1.4e-247 yjcE P NhaP-type Na H and K H antiporters
KOKCBKAK_01221 9e-90 yjcE P NhaP-type Na H and K H antiporters
KOKCBKAK_01222 2.1e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KOKCBKAK_01223 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KOKCBKAK_01224 6.9e-13 MU outer membrane autotransporter barrel domain protein
KOKCBKAK_01225 5.1e-158 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOKCBKAK_01227 9e-75 XK27_03180 T universal stress protein
KOKCBKAK_01228 6.9e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KOKCBKAK_01229 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KOKCBKAK_01230 6.8e-101 pncA Q isochorismatase
KOKCBKAK_01231 1e-294 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOKCBKAK_01232 7.6e-58 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
KOKCBKAK_01233 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOKCBKAK_01234 6.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KOKCBKAK_01235 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOKCBKAK_01237 1.9e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOKCBKAK_01238 9.4e-31 S PQ loop repeat
KOKCBKAK_01239 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
KOKCBKAK_01240 2.7e-277 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
KOKCBKAK_01241 2.9e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
KOKCBKAK_01242 3.2e-57
KOKCBKAK_01243 8.2e-217 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOKCBKAK_01244 3.9e-63
KOKCBKAK_01245 1.2e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KOKCBKAK_01246 1.4e-98 yqeG S hydrolase of the HAD superfamily
KOKCBKAK_01247 7.8e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KOKCBKAK_01248 7.7e-49 yhbY J RNA-binding protein
KOKCBKAK_01249 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KOKCBKAK_01250 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KOKCBKAK_01251 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KOKCBKAK_01252 3.8e-139 yqeM Q Methyltransferase domain protein
KOKCBKAK_01253 1e-196 ylbM S Belongs to the UPF0348 family
KOKCBKAK_01255 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KOKCBKAK_01257 1.6e-103
KOKCBKAK_01260 3.1e-07
KOKCBKAK_01261 1.5e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KOKCBKAK_01262 1.4e-130 ecsA V abc transporter atp-binding protein
KOKCBKAK_01263 8.4e-177 ecsB U Bacterial ABC transporter protein EcsB
KOKCBKAK_01264 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
KOKCBKAK_01265 2.6e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KOKCBKAK_01267 4.4e-222 ytfP S Flavoprotein
KOKCBKAK_01268 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KOKCBKAK_01269 6.3e-63 XK27_02560 S cog cog2151
KOKCBKAK_01270 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
KOKCBKAK_01271 4.6e-103 dnaQ 2.7.7.7 L DNA polymerase III
KOKCBKAK_01272 1.1e-130 K transcriptional regulator, MerR family
KOKCBKAK_01273 0.0 V ABC transporter (Permease
KOKCBKAK_01274 5e-125 V abc transporter atp-binding protein
KOKCBKAK_01276 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KOKCBKAK_01277 7.1e-44
KOKCBKAK_01278 0.0 ctpE P E1-E2 ATPase
KOKCBKAK_01279 4.3e-59
KOKCBKAK_01280 1.2e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
KOKCBKAK_01281 1.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KOKCBKAK_01282 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KOKCBKAK_01283 2.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KOKCBKAK_01284 9.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KOKCBKAK_01285 2.3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KOKCBKAK_01286 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KOKCBKAK_01287 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KOKCBKAK_01288 4.6e-155 EGP Major facilitator Superfamily
KOKCBKAK_01289 1.8e-72 copY K negative regulation of transcription, DNA-templated
KOKCBKAK_01290 0.0 copA 3.6.3.54 P P-type ATPase
KOKCBKAK_01291 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KOKCBKAK_01292 2.3e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KOKCBKAK_01293 3e-114 papP P ABC transporter (Permease
KOKCBKAK_01294 2.5e-105 P ABC transporter (Permease
KOKCBKAK_01295 5.8e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOKCBKAK_01296 1.7e-154 cjaA ET ABC transporter substrate-binding protein
KOKCBKAK_01300 2.5e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KOKCBKAK_01301 4.8e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
KOKCBKAK_01302 1.9e-88 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_01303 1.3e-151 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KOKCBKAK_01304 2.5e-109 pgm G Belongs to the phosphoglycerate mutase family
KOKCBKAK_01305 7e-107 G Belongs to the phosphoglycerate mutase family
KOKCBKAK_01306 1.5e-109 G Belongs to the phosphoglycerate mutase family
KOKCBKAK_01307 3.5e-200 S hmm pf01594
KOKCBKAK_01308 9.2e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOKCBKAK_01309 4.9e-39 S granule-associated protein
KOKCBKAK_01310 4.7e-288 S unusual protein kinase
KOKCBKAK_01311 6.7e-105 estA E Lysophospholipase L1 and related esterases
KOKCBKAK_01312 1.5e-160 rssA S Phospholipase, patatin family
KOKCBKAK_01313 2.4e-253 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
KOKCBKAK_01314 6e-219 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOKCBKAK_01315 1.1e-118 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KOKCBKAK_01316 7.5e-236 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KOKCBKAK_01317 0.0 S the current gene model (or a revised gene model) may contain a frame shift
KOKCBKAK_01318 3e-192 L PFAM Integrase, catalytic core
KOKCBKAK_01319 0.0 cas3 L CRISPR-associated helicase cas3
KOKCBKAK_01320 0.0 casA L An automated process has identified a potential problem with this gene model
KOKCBKAK_01321 7.5e-106 casB S CRISPR system CASCADE complex protein CasB
KOKCBKAK_01322 1.4e-182 casC L CT1975-like protein
KOKCBKAK_01323 7.7e-137 casD S CRISPR system CASCADE complex protein CasD
KOKCBKAK_01324 3.4e-112 casE S CRISPR system CASCADE complex protein CasE
KOKCBKAK_01325 2.1e-171 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOKCBKAK_01326 1.2e-168 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
KOKCBKAK_01328 2.2e-235 2.7.13.3 T protein histidine kinase activity
KOKCBKAK_01329 1.1e-215 hpk9 2.7.13.3 T protein histidine kinase activity
KOKCBKAK_01330 7.8e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KOKCBKAK_01331 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KOKCBKAK_01332 5.4e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KOKCBKAK_01333 0.0 lpdA 1.8.1.4 C Dehydrogenase
KOKCBKAK_01334 8e-38 L Transposase
KOKCBKAK_01337 5.9e-55 bta 1.8.1.8 CO cell redox homeostasis
KOKCBKAK_01338 8.2e-59 L thioesterase
KOKCBKAK_01339 1.3e-142 S Macro domain protein
KOKCBKAK_01340 6.3e-51 trxA O Belongs to the thioredoxin family
KOKCBKAK_01341 2.5e-74 yccU S CoA-binding protein
KOKCBKAK_01342 6.6e-145 tatD L Hydrolase, tatd
KOKCBKAK_01343 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KOKCBKAK_01344 2.9e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOKCBKAK_01346 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KOKCBKAK_01347 2.3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KOKCBKAK_01348 1.6e-117 thiN 2.7.6.2 H thiamine pyrophosphokinase
KOKCBKAK_01349 1.6e-169 rmuC S RmuC domain protein
KOKCBKAK_01350 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
KOKCBKAK_01351 4e-142 purR 2.4.2.7 F operon repressor
KOKCBKAK_01352 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KOKCBKAK_01353 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KOKCBKAK_01354 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KOKCBKAK_01355 7.9e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KOKCBKAK_01356 7.1e-14
KOKCBKAK_01357 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KOKCBKAK_01358 3e-87 S Fusaric acid resistance protein-like
KOKCBKAK_01359 2.5e-62 glnR K Transcriptional regulator
KOKCBKAK_01360 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
KOKCBKAK_01361 6.6e-116 pscB M CHAP domain protein
KOKCBKAK_01362 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOKCBKAK_01363 1.5e-33 ykzG S Belongs to the UPF0356 family
KOKCBKAK_01364 3.9e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KOKCBKAK_01365 9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KOKCBKAK_01366 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KOKCBKAK_01367 3.9e-114 azlC E AzlC protein
KOKCBKAK_01368 3.7e-46 azlD S branched-chain amino acid
KOKCBKAK_01369 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KOKCBKAK_01370 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KOKCBKAK_01371 1.3e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOKCBKAK_01372 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KOKCBKAK_01373 5.1e-93 cvpA S toxin biosynthetic process
KOKCBKAK_01374 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KOKCBKAK_01375 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KOKCBKAK_01377 6.1e-229 mutY L A G-specific adenine glycosylase
KOKCBKAK_01378 1.5e-42 XK27_05745
KOKCBKAK_01379 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KOKCBKAK_01380 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KOKCBKAK_01381 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KOKCBKAK_01383 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
KOKCBKAK_01384 8.4e-168 corA P COG0598 Mg2 and Co2 transporters
KOKCBKAK_01385 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KOKCBKAK_01389 4.7e-32 blpT
KOKCBKAK_01390 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_01391 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_01392 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_01393 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_01395 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
KOKCBKAK_01396 4.8e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KOKCBKAK_01397 3.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KOKCBKAK_01398 2.4e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOKCBKAK_01399 1.9e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KOKCBKAK_01400 8.6e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KOKCBKAK_01401 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KOKCBKAK_01402 1.7e-137
KOKCBKAK_01404 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
KOKCBKAK_01405 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
KOKCBKAK_01407 2e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOKCBKAK_01408 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
KOKCBKAK_01409 1.1e-153 endA F DNA RNA non-specific endonuclease
KOKCBKAK_01410 2.9e-111 tcyB_2 P ABC transporter (permease)
KOKCBKAK_01411 1.9e-116 gltJ P ABC transporter (Permease
KOKCBKAK_01412 7.5e-144 peb1A ET Belongs to the bacterial solute-binding protein 3 family
KOKCBKAK_01413 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOKCBKAK_01414 5e-111 tcyB_2 P ABC transporter (permease)
KOKCBKAK_01415 1.9e-116 gltJ P ABC transporter (Permease
KOKCBKAK_01416 1.9e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KOKCBKAK_01417 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOKCBKAK_01418 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOKCBKAK_01419 1e-235 vicK 2.7.13.3 T Histidine kinase
KOKCBKAK_01420 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KOKCBKAK_01421 1.3e-57 S Protein of unknown function (DUF454)
KOKCBKAK_01422 2.6e-206 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KOKCBKAK_01423 3.3e-144 yidA S hydrolases of the HAD superfamily
KOKCBKAK_01424 2.9e-154 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
KOKCBKAK_01425 1.3e-137 XK27_00120 2.4.2.3 F Phosphorylase superfamily
KOKCBKAK_01426 5.3e-68 ywiB S Domain of unknown function (DUF1934)
KOKCBKAK_01427 0.0 pacL 3.6.3.8 P cation transport ATPase
KOKCBKAK_01428 8.2e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KOKCBKAK_01429 5.6e-163 yjjH S Calcineurin-like phosphoesterase
KOKCBKAK_01430 1e-201 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KOKCBKAK_01431 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KOKCBKAK_01432 3.2e-124 ftsE D cell division ATP-binding protein FtsE
KOKCBKAK_01433 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KOKCBKAK_01434 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KOKCBKAK_01435 1.3e-178 yubA S permease
KOKCBKAK_01436 4.4e-225 G COG0457 FOG TPR repeat
KOKCBKAK_01437 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KOKCBKAK_01438 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KOKCBKAK_01439 1.9e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KOKCBKAK_01440 3.9e-87 ebsA S Family of unknown function (DUF5322)
KOKCBKAK_01441 5.5e-17 M LysM domain
KOKCBKAK_01442 2.1e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KOKCBKAK_01443 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KOKCBKAK_01444 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KOKCBKAK_01445 9.7e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KOKCBKAK_01446 1.2e-77 XK27_03610 K Gnat family
KOKCBKAK_01447 2.5e-89 yybC
KOKCBKAK_01448 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KOKCBKAK_01449 2.5e-269 pepV 3.5.1.18 E Dipeptidase
KOKCBKAK_01450 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
KOKCBKAK_01451 2.3e-241 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KOKCBKAK_01452 4e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KOKCBKAK_01453 7.2e-116 cps4C M biosynthesis protein
KOKCBKAK_01454 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
KOKCBKAK_01455 2.8e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KOKCBKAK_01456 1.7e-126 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KOKCBKAK_01457 7.4e-160 licD M LICD family
KOKCBKAK_01458 2e-163 S Glycosyl transferase family 2
KOKCBKAK_01459 4.4e-205 M glycosyl transferase group 1
KOKCBKAK_01460 4e-85
KOKCBKAK_01461 2.7e-171 S glycosyl transferase family 2
KOKCBKAK_01462 5.3e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KOKCBKAK_01463 0.0 M Polysaccharide biosynthesis protein
KOKCBKAK_01464 5.5e-243 S Polysaccharide biosynthesis protein
KOKCBKAK_01465 6.8e-113 L Transposase
KOKCBKAK_01466 3.9e-78 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_01467 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_01468 6.3e-188 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KOKCBKAK_01469 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
KOKCBKAK_01470 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KOKCBKAK_01471 6.3e-61 yqhY S protein conserved in bacteria
KOKCBKAK_01472 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KOKCBKAK_01473 1.7e-179 scrR K Transcriptional regulator
KOKCBKAK_01474 1.3e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
KOKCBKAK_01475 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KOKCBKAK_01476 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KOKCBKAK_01477 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
KOKCBKAK_01479 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOKCBKAK_01480 3.3e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KOKCBKAK_01481 1.9e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KOKCBKAK_01482 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KOKCBKAK_01483 2.2e-191 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KOKCBKAK_01484 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KOKCBKAK_01488 2.9e-31 yozG K Transcriptional regulator
KOKCBKAK_01490 2e-180 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KOKCBKAK_01491 2.1e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KOKCBKAK_01492 1.5e-110 yebC M Membrane
KOKCBKAK_01493 7.8e-297 KT response to antibiotic
KOKCBKAK_01494 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
KOKCBKAK_01495 6.3e-112 liaI S membrane
KOKCBKAK_01496 9.2e-300 O MreB/Mbl protein
KOKCBKAK_01498 1.3e-145 V Psort location CytoplasmicMembrane, score
KOKCBKAK_01501 8.9e-14
KOKCBKAK_01502 3.8e-243 dcuS 2.7.13.3 T protein histidine kinase activity
KOKCBKAK_01503 2.3e-246 2.7.13.3 T protein histidine kinase activity
KOKCBKAK_01504 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KOKCBKAK_01505 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KOKCBKAK_01506 1.4e-125 S Protein of unknown function (DUF554)
KOKCBKAK_01507 3.4e-132 ecsA_2 V abc transporter atp-binding protein
KOKCBKAK_01508 2.1e-272 XK27_00765
KOKCBKAK_01509 5.2e-142 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KOKCBKAK_01510 1.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KOKCBKAK_01511 4.3e-65 yhaI S Protein of unknown function (DUF805)
KOKCBKAK_01512 5e-69 yhaI J Protein of unknown function (DUF805)
KOKCBKAK_01515 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KOKCBKAK_01516 2.4e-45 ftsL D cell division protein FtsL
KOKCBKAK_01517 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KOKCBKAK_01518 4.5e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KOKCBKAK_01519 1.2e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KOKCBKAK_01520 5.2e-156 V ATPases associated with a variety of cellular activities
KOKCBKAK_01521 3.9e-123
KOKCBKAK_01522 1.3e-115 KT COG3279 Response regulator of the LytR AlgR family
KOKCBKAK_01523 3.9e-171 T GHKL domain
KOKCBKAK_01526 2e-258 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KOKCBKAK_01527 5.6e-63 yutD J protein conserved in bacteria
KOKCBKAK_01528 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KOKCBKAK_01529 6.1e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
KOKCBKAK_01531 0.0 mdlA V abc transporter atp-binding protein
KOKCBKAK_01532 0.0 mdlB V abc transporter atp-binding protein
KOKCBKAK_01533 1.5e-25 S Bacteriocin class II with double-glycine leader peptide
KOKCBKAK_01535 2.7e-228 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KOKCBKAK_01536 1.3e-134 agrA KT LytTr DNA-binding domain
KOKCBKAK_01538 5.4e-44 spiA K sequence-specific DNA binding
KOKCBKAK_01541 4.6e-193 L PFAM Integrase, catalytic core
KOKCBKAK_01542 1.9e-88 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_01554 1.5e-86 sigH K DNA-templated transcription, initiation
KOKCBKAK_01555 6.9e-139 ykuT M mechanosensitive ion channel
KOKCBKAK_01556 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KOKCBKAK_01557 1e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KOKCBKAK_01558 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KOKCBKAK_01559 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
KOKCBKAK_01560 4.6e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KOKCBKAK_01561 5e-84 XK27_02675 K Acetyltransferase GNAT Family
KOKCBKAK_01562 1.1e-175 prmA J Ribosomal protein L11 methyltransferase
KOKCBKAK_01563 1e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KOKCBKAK_01564 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KOKCBKAK_01565 3.1e-83 nrdI F Belongs to the NrdI family
KOKCBKAK_01566 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KOKCBKAK_01567 1.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KOKCBKAK_01568 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KOKCBKAK_01569 1.9e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KOKCBKAK_01570 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOKCBKAK_01571 2.9e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KOKCBKAK_01572 1.9e-193 yhjX P Major Facilitator
KOKCBKAK_01573 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KOKCBKAK_01574 1.6e-84 V VanZ like family
KOKCBKAK_01575 2.4e-180 D nuclear chromosome segregation
KOKCBKAK_01576 5e-123 glnQ E abc transporter atp-binding protein
KOKCBKAK_01577 4.6e-272 glnP P ABC transporter
KOKCBKAK_01578 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KOKCBKAK_01579 8.3e-18 S Protein of unknown function (DUF3021)
KOKCBKAK_01580 2.7e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KOKCBKAK_01581 1.9e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
KOKCBKAK_01582 6.3e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KOKCBKAK_01583 6.3e-235 sufD O assembly protein SufD
KOKCBKAK_01584 1.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KOKCBKAK_01585 2.3e-72 nifU C SUF system FeS assembly protein, NifU family
KOKCBKAK_01586 1e-273 sufB O assembly protein SufB
KOKCBKAK_01587 1.1e-310 oppA E ABC transporter substrate-binding protein
KOKCBKAK_01588 9.7e-161 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOKCBKAK_01589 1.9e-165 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOKCBKAK_01590 6.6e-198 oppD P Belongs to the ABC transporter superfamily
KOKCBKAK_01591 5.8e-169 oppF P Belongs to the ABC transporter superfamily
KOKCBKAK_01592 8e-26
KOKCBKAK_01593 6.2e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KOKCBKAK_01594 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOKCBKAK_01595 4.2e-69 adcR K transcriptional
KOKCBKAK_01596 9.2e-135 adcC P ABC transporter, ATP-binding protein
KOKCBKAK_01597 5.6e-128 adcB P ABC transporter (Permease
KOKCBKAK_01598 4.5e-161 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KOKCBKAK_01599 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KOKCBKAK_01600 3.4e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KOKCBKAK_01601 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
KOKCBKAK_01602 1.6e-149 Z012_04635 K sequence-specific DNA binding
KOKCBKAK_01603 8e-280 V ABC transporter
KOKCBKAK_01604 9.4e-127 yeeN K transcriptional regulatory protein
KOKCBKAK_01605 3.1e-48 yajC U protein transport
KOKCBKAK_01606 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KOKCBKAK_01607 8.5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KOKCBKAK_01608 4.7e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KOKCBKAK_01609 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KOKCBKAK_01610 0.0 WQ51_06230 S ABC transporter
KOKCBKAK_01611 4e-142 cmpC S abc transporter atp-binding protein
KOKCBKAK_01612 1.9e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KOKCBKAK_01613 1.9e-284 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KOKCBKAK_01615 5.5e-44
KOKCBKAK_01616 4.2e-53 S TM2 domain
KOKCBKAK_01617 3.1e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOKCBKAK_01618 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOKCBKAK_01619 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KOKCBKAK_01620 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
KOKCBKAK_01621 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KOKCBKAK_01622 2.3e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KOKCBKAK_01623 2e-146 cof S Sucrose-6F-phosphate phosphohydrolase
KOKCBKAK_01624 8.2e-137 glcR K transcriptional regulator (DeoR family)
KOKCBKAK_01625 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOKCBKAK_01626 9.6e-77 K transcriptional
KOKCBKAK_01627 1.4e-239 S COG1073 Hydrolases of the alpha beta superfamily
KOKCBKAK_01628 1.2e-25 yjdF S Protein of unknown function (DUF2992)
KOKCBKAK_01629 4.4e-155 cylA V abc transporter atp-binding protein
KOKCBKAK_01630 4.3e-131 cylB V ABC-2 type transporter
KOKCBKAK_01631 9e-75 K COG3279 Response regulator of the LytR AlgR family
KOKCBKAK_01632 8.9e-32 S Protein of unknown function (DUF3021)
KOKCBKAK_01633 9.6e-124 mta K Transcriptional
KOKCBKAK_01634 2e-118 yhcA V abc transporter atp-binding protein
KOKCBKAK_01635 6.8e-210 macB_2 V FtsX-like permease family
KOKCBKAK_01636 1.9e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KOKCBKAK_01637 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KOKCBKAK_01638 1.1e-77 yhaI S Protein of unknown function (DUF805)
KOKCBKAK_01639 1.5e-255 pepC 3.4.22.40 E aminopeptidase
KOKCBKAK_01640 2.7e-109 L Transposase
KOKCBKAK_01641 2.1e-79 L Transposase
KOKCBKAK_01642 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOKCBKAK_01643 8.1e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KOKCBKAK_01644 9.8e-94 ypsA S Belongs to the UPF0398 family
KOKCBKAK_01645 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KOKCBKAK_01646 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KOKCBKAK_01647 3.5e-280 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KOKCBKAK_01648 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KOKCBKAK_01649 7.4e-23
KOKCBKAK_01650 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KOKCBKAK_01651 5.9e-88 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
KOKCBKAK_01652 2e-296 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KOKCBKAK_01653 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOKCBKAK_01654 2.2e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOKCBKAK_01655 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KOKCBKAK_01656 1.9e-127 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOKCBKAK_01657 2.5e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KOKCBKAK_01658 6.9e-103 ybhL S Belongs to the BI1 family
KOKCBKAK_01659 8.4e-13 ycdA S Domain of unknown function (DUF4352)
KOKCBKAK_01660 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KOKCBKAK_01661 1.4e-90 K transcriptional regulator
KOKCBKAK_01662 1.6e-36 yneF S UPF0154 protein
KOKCBKAK_01663 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KOKCBKAK_01664 3.5e-185 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KOKCBKAK_01665 1.1e-97 XK27_09740 S Phosphoesterase
KOKCBKAK_01666 8.3e-87 ykuL S CBS domain
KOKCBKAK_01667 1.7e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KOKCBKAK_01668 1e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KOKCBKAK_01669 6.5e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KOKCBKAK_01670 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOKCBKAK_01671 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
KOKCBKAK_01672 9.3e-259 trkH P Cation transport protein
KOKCBKAK_01673 1e-246 trkA P Potassium transporter peripheral membrane component
KOKCBKAK_01674 1.4e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KOKCBKAK_01675 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KOKCBKAK_01676 2.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KOKCBKAK_01677 7.2e-65 L Transposase (IS116 IS110 IS902 family)
KOKCBKAK_01678 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
KOKCBKAK_01679 1.9e-88 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_01682 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KOKCBKAK_01683 1.7e-84 yxjI S LURP-one-related
KOKCBKAK_01684 2.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KOKCBKAK_01685 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
KOKCBKAK_01686 4.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
KOKCBKAK_01687 0.0 pepF E oligoendopeptidase F
KOKCBKAK_01688 4.8e-179 coiA 3.6.4.12 S Competence protein
KOKCBKAK_01689 3.4e-32 L transposition
KOKCBKAK_01690 5.9e-23 insK L Integrase core domain protein
KOKCBKAK_01691 1.6e-22 L overlaps another CDS with the same product name
KOKCBKAK_01692 1.5e-160 S CHAP domain
KOKCBKAK_01693 1.1e-302 S Glucan-binding protein C
KOKCBKAK_01694 2.7e-105 S CAAX amino terminal protease family protein
KOKCBKAK_01695 4.7e-168 K transcriptional regulator (lysR family)
KOKCBKAK_01696 9.6e-163 S reductase
KOKCBKAK_01697 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KOKCBKAK_01702 2.8e-191 phoH T phosphate starvation-inducible protein PhoH
KOKCBKAK_01703 6e-137 sip M LysM domain protein
KOKCBKAK_01704 3.7e-34 yozE S Belongs to the UPF0346 family
KOKCBKAK_01705 4.5e-160 cvfB S Protein conserved in bacteria
KOKCBKAK_01706 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KOKCBKAK_01707 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KOKCBKAK_01708 8.5e-213 sptS 2.7.13.3 T Histidine kinase
KOKCBKAK_01709 1.7e-117 T response regulator
KOKCBKAK_01710 5.1e-113 2.7.6.5 S Region found in RelA / SpoT proteins
KOKCBKAK_01711 3.3e-112 K Acetyltransferase (GNAT) family
KOKCBKAK_01712 0.0 lmrA2 V abc transporter atp-binding protein
KOKCBKAK_01713 5e-310 lmrA1 V abc transporter atp-binding protein
KOKCBKAK_01714 3.3e-74 K DNA-binding transcription factor activity
KOKCBKAK_01715 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KOKCBKAK_01716 4e-282 S Psort location CytoplasmicMembrane, score
KOKCBKAK_01717 2.8e-257 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KOKCBKAK_01718 2.9e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KOKCBKAK_01719 8.1e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KOKCBKAK_01720 1e-26 U response to pH
KOKCBKAK_01721 0.0 yfmR S abc transporter atp-binding protein
KOKCBKAK_01722 5.4e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KOKCBKAK_01723 6.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KOKCBKAK_01724 1.4e-150 XK27_08360 S EDD domain protein, DegV family
KOKCBKAK_01725 5e-63 WQ51_03320 S cog cog4835
KOKCBKAK_01726 4.5e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KOKCBKAK_01727 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KOKCBKAK_01728 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KOKCBKAK_01729 7.1e-95 2.3.1.128 K acetyltransferase
KOKCBKAK_01730 6.7e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KOKCBKAK_01731 1.1e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KOKCBKAK_01732 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KOKCBKAK_01733 4.4e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KOKCBKAK_01735 7.6e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KOKCBKAK_01736 7.1e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KOKCBKAK_01737 0.0 fruA 2.7.1.202 G phosphotransferase system
KOKCBKAK_01738 8.4e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KOKCBKAK_01739 7e-125 fruR K transcriptional
KOKCBKAK_01740 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
KOKCBKAK_01741 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KOKCBKAK_01742 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KOKCBKAK_01743 2.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KOKCBKAK_01744 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KOKCBKAK_01745 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KOKCBKAK_01746 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KOKCBKAK_01747 1.7e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KOKCBKAK_01748 6.9e-125 IQ reductase
KOKCBKAK_01749 2.3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KOKCBKAK_01750 2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KOKCBKAK_01751 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOKCBKAK_01752 2.7e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KOKCBKAK_01753 5.2e-72 marR K Transcriptional regulator, MarR family
KOKCBKAK_01754 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KOKCBKAK_01755 1.1e-113 S HAD hydrolase, family IA, variant 3
KOKCBKAK_01756 1.8e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
KOKCBKAK_01757 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
KOKCBKAK_01758 3.8e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOKCBKAK_01759 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
KOKCBKAK_01760 7.8e-102 ygaC J Belongs to the UPF0374 family
KOKCBKAK_01761 1.4e-107 S Domain of unknown function (DUF1803)
KOKCBKAK_01762 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KOKCBKAK_01770 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KOKCBKAK_01771 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KOKCBKAK_01772 1.1e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KOKCBKAK_01773 4.5e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KOKCBKAK_01775 3e-60 divIC D Septum formation initiator
KOKCBKAK_01776 6.3e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KOKCBKAK_01777 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KOKCBKAK_01778 2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KOKCBKAK_01779 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KOKCBKAK_01780 1.1e-29 yyzM S Protein conserved in bacteria
KOKCBKAK_01781 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KOKCBKAK_01782 1e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KOKCBKAK_01783 1.1e-133 parB K Belongs to the ParB family
KOKCBKAK_01784 4.6e-206 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KOKCBKAK_01785 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KOKCBKAK_01786 2.4e-119 yoaK S Protein of unknown function (DUF1275)
KOKCBKAK_01790 0.0 XK27_10405 S Bacterial membrane protein YfhO
KOKCBKAK_01791 4.3e-305 ybiT S abc transporter atp-binding protein
KOKCBKAK_01792 7.1e-153 yvjA S membrane
KOKCBKAK_01793 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KOKCBKAK_01794 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KOKCBKAK_01795 1e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KOKCBKAK_01796 3.7e-58 yaaA S S4 domain protein YaaA
KOKCBKAK_01797 1.9e-231 ymfF S Peptidase M16
KOKCBKAK_01798 5.2e-237 ymfH S Peptidase M16
KOKCBKAK_01799 1.7e-130 S sequence-specific DNA binding
KOKCBKAK_01800 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOKCBKAK_01801 4.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOKCBKAK_01802 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOKCBKAK_01803 3.7e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOKCBKAK_01804 6.5e-232 L Transposase
KOKCBKAK_01805 1.4e-56 lytE M LysM domain protein
KOKCBKAK_01806 5.8e-65 isaA GH23 M Immunodominant staphylococcal antigen A
KOKCBKAK_01807 6e-305 S Bacterial membrane protein, YfhO
KOKCBKAK_01808 5.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KOKCBKAK_01809 2.4e-99 yvbG U UPF0056 membrane protein
KOKCBKAK_01810 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KOKCBKAK_01811 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KOKCBKAK_01812 2.2e-73 rplI J binds to the 23S rRNA
KOKCBKAK_01813 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KOKCBKAK_01814 1.8e-47 veg S Biofilm formation stimulator VEG
KOKCBKAK_01815 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KOKCBKAK_01816 1.9e-10
KOKCBKAK_01817 4.1e-54 ypaA M Membrane
KOKCBKAK_01818 3.8e-96 XK27_06935 K transcriptional regulator
KOKCBKAK_01819 2.1e-159 XK27_06930 V domain protein
KOKCBKAK_01820 9.7e-107 S Putative adhesin
KOKCBKAK_01821 6.4e-65 XK27_06920 S Protein of unknown function (DUF1700)
KOKCBKAK_01822 1.6e-52 K transcriptional regulator, PadR family
KOKCBKAK_01823 2.4e-115 nudL L hydrolase
KOKCBKAK_01826 1.1e-07
KOKCBKAK_01827 1.1e-16 U Preprotein translocase subunit SecB
KOKCBKAK_01829 3.7e-12
KOKCBKAK_01830 2.7e-217 sip L Phage integrase, N-terminal SAM-like domain
KOKCBKAK_01831 1.5e-34 S MerR HTH family regulatory protein
KOKCBKAK_01832 1.6e-170 isp2 S pathogenesis
KOKCBKAK_01833 4.4e-30
KOKCBKAK_01834 4.5e-261
KOKCBKAK_01835 0.0 yddE S AAA-like domain
KOKCBKAK_01836 6.7e-69 S TcpE family
KOKCBKAK_01837 3.2e-33
KOKCBKAK_01838 1.9e-157 S Conjugative transposon protein TcpC
KOKCBKAK_01839 3e-88
KOKCBKAK_01840 4.3e-33
KOKCBKAK_01841 2.7e-222 K Replication initiation factor
KOKCBKAK_01842 7.2e-214 L Belongs to the 'phage' integrase family
KOKCBKAK_01843 4.5e-10 S Domain of unknown function (DUF3173)
KOKCBKAK_01844 2.6e-87 L Replication initiation factor
KOKCBKAK_01846 1.5e-12 K Transcriptional
KOKCBKAK_01847 8.6e-105 yiiE S protein homotetramerization
KOKCBKAK_01848 5.2e-277 ydcQ D Ftsk spoiiie family protein
KOKCBKAK_01849 1.2e-71
KOKCBKAK_01850 4.5e-43
KOKCBKAK_01851 1.2e-50 K Bacteriophage CI repressor helix-turn-helix domain
KOKCBKAK_01853 7.8e-128 E IrrE N-terminal-like domain
KOKCBKAK_01854 6.6e-109 K Peptidase S24-like
KOKCBKAK_01855 8.1e-24
KOKCBKAK_01856 5.2e-213 dcm 2.1.1.37 H Cytosine-specific methyltransferase
KOKCBKAK_01857 4.2e-129 L DNA mismatch repair enzyme MutH
KOKCBKAK_01860 6.9e-79 S EcsC protein family
KOKCBKAK_01862 2.9e-116
KOKCBKAK_01863 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KOKCBKAK_01864 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KOKCBKAK_01865 6.1e-218 metE 2.1.1.14 E Methionine synthase
KOKCBKAK_01866 6.5e-238 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KOKCBKAK_01867 1.6e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
KOKCBKAK_01869 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KOKCBKAK_01870 9.3e-167 XK27_01785 S cog cog1284
KOKCBKAK_01871 7.5e-121 yaaA S Belongs to the UPF0246 family
KOKCBKAK_01872 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOKCBKAK_01873 3.5e-88 XK27_10930 K acetyltransferase
KOKCBKAK_01874 7.5e-14
KOKCBKAK_01875 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KOKCBKAK_01876 4.7e-291 ccs S the current gene model (or a revised gene model) may contain a frame shift
KOKCBKAK_01877 3.2e-44 yrzB S Belongs to the UPF0473 family
KOKCBKAK_01878 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KOKCBKAK_01879 6.3e-44 yrzL S Belongs to the UPF0297 family
KOKCBKAK_01880 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KOKCBKAK_01881 3.7e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KOKCBKAK_01883 5.7e-94 adk 2.7.4.3 F topology modulation protein
KOKCBKAK_01884 6.6e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KOKCBKAK_01885 2.9e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KOKCBKAK_01886 9.7e-36 XK27_09805 S MORN repeat protein
KOKCBKAK_01887 0.0 XK27_09800 I Acyltransferase
KOKCBKAK_01888 6.1e-193 L PFAM Integrase, catalytic core
KOKCBKAK_01889 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KOKCBKAK_01890 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KOKCBKAK_01891 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KOKCBKAK_01892 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KOKCBKAK_01893 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KOKCBKAK_01894 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KOKCBKAK_01895 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KOKCBKAK_01896 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KOKCBKAK_01897 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KOKCBKAK_01898 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KOKCBKAK_01899 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KOKCBKAK_01900 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KOKCBKAK_01901 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KOKCBKAK_01902 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KOKCBKAK_01903 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KOKCBKAK_01904 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOKCBKAK_01905 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KOKCBKAK_01906 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KOKCBKAK_01907 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KOKCBKAK_01908 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KOKCBKAK_01909 1.9e-23 rpmD J ribosomal protein l30
KOKCBKAK_01910 1.7e-57 rplO J binds to the 23S rRNA
KOKCBKAK_01911 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KOKCBKAK_01912 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KOKCBKAK_01913 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KOKCBKAK_01914 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KOKCBKAK_01915 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KOKCBKAK_01916 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KOKCBKAK_01917 4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOKCBKAK_01918 4.4e-62 rplQ J ribosomal protein l17
KOKCBKAK_01919 5.1e-240 6.3.2.2 H gamma-glutamylcysteine synthetase
KOKCBKAK_01921 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
KOKCBKAK_01924 9.7e-95 ywlG S Belongs to the UPF0340 family
KOKCBKAK_01925 1.8e-117 treR K trehalose operon
KOKCBKAK_01926 6.8e-289 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KOKCBKAK_01927 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KOKCBKAK_01928 0.0 pepO 3.4.24.71 O Peptidase family M13
KOKCBKAK_01929 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KOKCBKAK_01932 3.5e-277 thrC 4.2.3.1 E Threonine synthase
KOKCBKAK_01933 2.1e-225 norN V Mate efflux family protein
KOKCBKAK_01934 1.4e-57 asp S cog cog1302
KOKCBKAK_01935 9.3e-303 yloV S kinase related to dihydroxyacetone kinase
KOKCBKAK_01936 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KOKCBKAK_01937 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KOKCBKAK_01938 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
KOKCBKAK_01939 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KOKCBKAK_01940 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOKCBKAK_01941 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOKCBKAK_01942 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOKCBKAK_01943 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOKCBKAK_01944 1e-68 S cog cog4699
KOKCBKAK_01945 2.4e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KOKCBKAK_01946 1.3e-143 cglB U protein transport across the cell outer membrane
KOKCBKAK_01947 1.5e-42 comGC U Required for transformation and DNA binding
KOKCBKAK_01948 8.4e-70 cglD NU Competence protein
KOKCBKAK_01949 8.2e-16 NU Type II secretory pathway pseudopilin
KOKCBKAK_01950 4.5e-71 comGF U Competence protein ComGF
KOKCBKAK_01951 2e-12 comGF U Putative Competence protein ComGF
KOKCBKAK_01952 1.1e-175 ytxK 2.1.1.72 L DNA methylase
KOKCBKAK_01953 3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOKCBKAK_01954 8.8e-27 lanR K sequence-specific DNA binding
KOKCBKAK_01955 2.4e-97 V CAAX protease self-immunity
KOKCBKAK_01957 9.6e-102 S CAAX amino terminal protease family protein
KOKCBKAK_01958 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOKCBKAK_01959 2.9e-201 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KOKCBKAK_01960 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
KOKCBKAK_01961 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KOKCBKAK_01962 2.6e-09 S NTF2 fold immunity protein
KOKCBKAK_01963 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOKCBKAK_01964 6.8e-187 yeeE S Sulphur transport
KOKCBKAK_01965 8.3e-37 yeeD O sulfur carrier activity
KOKCBKAK_01966 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KOKCBKAK_01967 1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KOKCBKAK_01971 1.2e-160 rrmA 2.1.1.187 Q methyltransferase
KOKCBKAK_01972 1.3e-139 S HAD hydrolase, family IA, variant
KOKCBKAK_01973 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KOKCBKAK_01974 2.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KOKCBKAK_01975 1.3e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KOKCBKAK_01976 5.4e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KOKCBKAK_01977 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KOKCBKAK_01978 3.7e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KOKCBKAK_01979 3.9e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
KOKCBKAK_01980 4.8e-140 fnt P Formate nitrite transporter
KOKCBKAK_01981 7.9e-230 XK27_09615 C reductase
KOKCBKAK_01982 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
KOKCBKAK_01983 2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KOKCBKAK_01984 3.3e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
KOKCBKAK_01985 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KOKCBKAK_01986 3.1e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
KOKCBKAK_01987 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KOKCBKAK_01988 1.2e-50 S Protein of unknown function (DUF3397)
KOKCBKAK_01989 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KOKCBKAK_01990 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KOKCBKAK_01991 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KOKCBKAK_01992 5.1e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KOKCBKAK_01993 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KOKCBKAK_01994 1.4e-151 hpk9 2.7.13.3 T protein histidine kinase activity
KOKCBKAK_01995 7.1e-210 hpk9 2.7.13.3 T protein histidine kinase activity
KOKCBKAK_01996 4.5e-244 fasC 2.7.13.3 T protein histidine kinase activity
KOKCBKAK_01997 2.8e-134 fasA KT Response regulator of the LytR AlgR family
KOKCBKAK_01998 3.8e-153 L PFAM Integrase, catalytic core
KOKCBKAK_01999 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KOKCBKAK_02000 1.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
KOKCBKAK_02001 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KOKCBKAK_02002 2.2e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOKCBKAK_02003 1.2e-151 jag S RNA-binding protein
KOKCBKAK_02004 2.9e-105 K Transcriptional regulator
KOKCBKAK_02005 2.6e-100 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
KOKCBKAK_02006 3.4e-14 rpmH J Ribosomal protein L34
KOKCBKAK_02007 3.5e-48 L COG1943 Transposase and inactivated derivatives
KOKCBKAK_02008 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)