ORF_ID e_value Gene_name EC_number CAZy COGs Description
IOOILHMJ_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOOILHMJ_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOOILHMJ_00003 2.4e-33 yaaA S S4 domain
IOOILHMJ_00004 4.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOOILHMJ_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
IOOILHMJ_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOOILHMJ_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOOILHMJ_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
IOOILHMJ_00011 3.7e-179 yaaC S YaaC-like Protein
IOOILHMJ_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IOOILHMJ_00013 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IOOILHMJ_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IOOILHMJ_00015 5.2e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IOOILHMJ_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOOILHMJ_00017 1.3e-09
IOOILHMJ_00018 8.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
IOOILHMJ_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
IOOILHMJ_00020 1.8e-208 yaaH M Glycoside Hydrolase Family
IOOILHMJ_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
IOOILHMJ_00022 2.5e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOOILHMJ_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOOILHMJ_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOOILHMJ_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOOILHMJ_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
IOOILHMJ_00027 1.1e-35 bofA S Sigma-K factor-processing regulatory protein BofA
IOOILHMJ_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
IOOILHMJ_00031 1.7e-30 csfB S Inhibitor of sigma-G Gin
IOOILHMJ_00032 2.2e-100 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IOOILHMJ_00033 1.3e-202 yaaN P Belongs to the TelA family
IOOILHMJ_00034 1.3e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
IOOILHMJ_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOOILHMJ_00036 2.2e-54 yaaQ S protein conserved in bacteria
IOOILHMJ_00037 2.6e-71 yaaR S protein conserved in bacteria
IOOILHMJ_00038 2e-180 holB 2.7.7.7 L DNA polymerase III
IOOILHMJ_00039 6.1e-146 yaaT S stage 0 sporulation protein
IOOILHMJ_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
IOOILHMJ_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
IOOILHMJ_00042 3.3e-49 yazA L endonuclease containing a URI domain
IOOILHMJ_00043 3.1e-148 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOOILHMJ_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
IOOILHMJ_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOOILHMJ_00046 1.2e-143 tatD L hydrolase, TatD
IOOILHMJ_00047 1.1e-189 rpfB GH23 T protein conserved in bacteria
IOOILHMJ_00048 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOOILHMJ_00049 4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOOILHMJ_00050 1.8e-135 yabG S peptidase
IOOILHMJ_00051 7.8e-39 veg S protein conserved in bacteria
IOOILHMJ_00052 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOOILHMJ_00053 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IOOILHMJ_00054 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
IOOILHMJ_00055 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IOOILHMJ_00056 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOOILHMJ_00057 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOOILHMJ_00058 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IOOILHMJ_00059 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOOILHMJ_00060 2.6e-38 yabK S Peptide ABC transporter permease
IOOILHMJ_00061 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOOILHMJ_00062 1.5e-92 spoVT K stage V sporulation protein
IOOILHMJ_00063 3.2e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOOILHMJ_00064 4.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IOOILHMJ_00065 3.3e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IOOILHMJ_00066 1.5e-49 yabP S Sporulation protein YabP
IOOILHMJ_00067 4e-105 yabQ S spore cortex biosynthesis protein
IOOILHMJ_00068 1.1e-44 divIC D Septum formation initiator
IOOILHMJ_00069 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
IOOILHMJ_00072 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
IOOILHMJ_00073 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
IOOILHMJ_00074 7.4e-186 KLT serine threonine protein kinase
IOOILHMJ_00075 1.6e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOOILHMJ_00076 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOOILHMJ_00077 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOOILHMJ_00078 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IOOILHMJ_00079 6.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOOILHMJ_00080 9e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
IOOILHMJ_00081 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOOILHMJ_00082 7.4e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOOILHMJ_00083 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
IOOILHMJ_00084 7.9e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
IOOILHMJ_00085 3.8e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IOOILHMJ_00086 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOOILHMJ_00087 1.3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IOOILHMJ_00088 4.1e-30 yazB K transcriptional
IOOILHMJ_00089 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOOILHMJ_00090 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IOOILHMJ_00091 3.4e-39 S COG NOG14552 non supervised orthologous group
IOOILHMJ_00092 2.9e-76 ctsR K Belongs to the CtsR family
IOOILHMJ_00093 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
IOOILHMJ_00094 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IOOILHMJ_00095 0.0 clpC O Belongs to the ClpA ClpB family
IOOILHMJ_00096 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOOILHMJ_00097 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IOOILHMJ_00098 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
IOOILHMJ_00099 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOOILHMJ_00100 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IOOILHMJ_00101 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOOILHMJ_00102 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
IOOILHMJ_00103 5.5e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOOILHMJ_00104 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOOILHMJ_00105 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOOILHMJ_00106 1.2e-88 yacP S RNA-binding protein containing a PIN domain
IOOILHMJ_00107 4.4e-115 sigH K Belongs to the sigma-70 factor family
IOOILHMJ_00108 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOOILHMJ_00109 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
IOOILHMJ_00110 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOOILHMJ_00111 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOOILHMJ_00112 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOOILHMJ_00113 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOOILHMJ_00114 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
IOOILHMJ_00115 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOOILHMJ_00116 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOOILHMJ_00117 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
IOOILHMJ_00118 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOOILHMJ_00119 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOOILHMJ_00120 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOOILHMJ_00121 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOOILHMJ_00122 1e-181 ybaC 3.4.11.5 S Alpha/beta hydrolase family
IOOILHMJ_00123 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IOOILHMJ_00124 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOOILHMJ_00125 3e-105 rplD J Forms part of the polypeptide exit tunnel
IOOILHMJ_00126 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOOILHMJ_00127 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOOILHMJ_00128 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOOILHMJ_00129 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOOILHMJ_00130 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOOILHMJ_00131 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOOILHMJ_00132 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IOOILHMJ_00133 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOOILHMJ_00134 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOOILHMJ_00135 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOOILHMJ_00136 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOOILHMJ_00137 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOOILHMJ_00138 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOOILHMJ_00139 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOOILHMJ_00140 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOOILHMJ_00141 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOOILHMJ_00142 1.9e-23 rpmD J Ribosomal protein L30
IOOILHMJ_00143 1.8e-72 rplO J binds to the 23S rRNA
IOOILHMJ_00144 5.5e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOOILHMJ_00145 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOOILHMJ_00146 8.2e-142 map 3.4.11.18 E Methionine aminopeptidase
IOOILHMJ_00147 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOOILHMJ_00148 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IOOILHMJ_00149 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOOILHMJ_00150 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOOILHMJ_00151 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOOILHMJ_00152 3.6e-58 rplQ J Ribosomal protein L17
IOOILHMJ_00153 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOOILHMJ_00154 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOOILHMJ_00155 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOOILHMJ_00156 1.1e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOOILHMJ_00157 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOOILHMJ_00158 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IOOILHMJ_00159 5.3e-144 ybaJ Q Methyltransferase domain
IOOILHMJ_00160 1.3e-65 ybaK S Protein of unknown function (DUF2521)
IOOILHMJ_00161 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IOOILHMJ_00162 2.2e-196 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IOOILHMJ_00163 4.5e-84 gerD
IOOILHMJ_00164 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
IOOILHMJ_00165 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
IOOILHMJ_00166 3.4e-39 S COG NOG14552 non supervised orthologous group
IOOILHMJ_00167 3e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
IOOILHMJ_00168 6.6e-160 ybaS 1.1.1.58 S Na -dependent transporter
IOOILHMJ_00169 3.6e-137 ybbA S Putative esterase
IOOILHMJ_00170 8.7e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_00171 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_00172 1.2e-164 feuA P Iron-uptake system-binding protein
IOOILHMJ_00173 1.8e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
IOOILHMJ_00174 6.2e-235 ybbC 3.2.1.52 S protein conserved in bacteria
IOOILHMJ_00175 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
IOOILHMJ_00176 5.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
IOOILHMJ_00177 7.8e-231 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOOILHMJ_00178 1.4e-150 ybbH K transcriptional
IOOILHMJ_00179 1.1e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOOILHMJ_00180 3.2e-86 ybbJ J acetyltransferase
IOOILHMJ_00181 2.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
IOOILHMJ_00187 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_00188 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IOOILHMJ_00189 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOOILHMJ_00190 5.7e-224 ybbR S protein conserved in bacteria
IOOILHMJ_00191 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOOILHMJ_00192 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOOILHMJ_00193 4.7e-98 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
IOOILHMJ_00194 5e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IOOILHMJ_00195 0.0 ybcC S Belongs to the UPF0753 family
IOOILHMJ_00196 3.8e-93 can 4.2.1.1 P carbonic anhydrase
IOOILHMJ_00198 8.7e-47
IOOILHMJ_00199 8e-61 ybcI S Uncharacterized conserved protein (DUF2294)
IOOILHMJ_00200 5.1e-50 ybzH K Helix-turn-helix domain
IOOILHMJ_00201 5.5e-201 ybcL EGP Major facilitator Superfamily
IOOILHMJ_00202 7.6e-45
IOOILHMJ_00203 9e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOOILHMJ_00204 1.3e-122 T Transcriptional regulatory protein, C terminal
IOOILHMJ_00205 4.7e-169 T His Kinase A (phospho-acceptor) domain
IOOILHMJ_00207 3.3e-138 KLT Protein tyrosine kinase
IOOILHMJ_00208 8.5e-151 ybdN
IOOILHMJ_00209 7.5e-214 ybdO S Domain of unknown function (DUF4885)
IOOILHMJ_00210 2.2e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
IOOILHMJ_00211 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
IOOILHMJ_00212 4.9e-30 ybxH S Family of unknown function (DUF5370)
IOOILHMJ_00213 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
IOOILHMJ_00214 1.6e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
IOOILHMJ_00215 4.9e-41 ybyB
IOOILHMJ_00216 2e-289 ybeC E amino acid
IOOILHMJ_00217 2.9e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOOILHMJ_00218 7.3e-258 glpT G -transporter
IOOILHMJ_00219 5.5e-34 S Protein of unknown function (DUF2651)
IOOILHMJ_00220 3.3e-169 ybfA 3.4.15.5 K FR47-like protein
IOOILHMJ_00221 1.6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
IOOILHMJ_00223 1.8e-159 ybfH EG EamA-like transporter family
IOOILHMJ_00224 5.2e-145 msmR K AraC-like ligand binding domain
IOOILHMJ_00225 8e-148 draG 3.2.2.24 O ADP-ribosylglycohydrolase
IOOILHMJ_00226 6.4e-72
IOOILHMJ_00227 8e-32 M nucleic acid phosphodiester bond hydrolysis
IOOILHMJ_00228 7.6e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOOILHMJ_00229 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
IOOILHMJ_00231 6.3e-165 S Alpha/beta hydrolase family
IOOILHMJ_00232 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOOILHMJ_00233 2.7e-85 ybfM S SNARE associated Golgi protein
IOOILHMJ_00234 3.1e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IOOILHMJ_00235 2.6e-40 ybfN
IOOILHMJ_00236 3.9e-251 S Erythromycin esterase
IOOILHMJ_00237 6.6e-192 yceA S Belongs to the UPF0176 family
IOOILHMJ_00238 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOOILHMJ_00239 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOOILHMJ_00240 4.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOOILHMJ_00241 6.5e-128 K UTRA
IOOILHMJ_00243 1e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IOOILHMJ_00244 6.3e-260 mmuP E amino acid
IOOILHMJ_00245 1.5e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
IOOILHMJ_00247 1.6e-255 agcS E Sodium alanine symporter
IOOILHMJ_00248 1.4e-186 glsA 3.5.1.2 E Belongs to the glutaminase family
IOOILHMJ_00249 2.1e-228 phoQ 2.7.13.3 T Histidine kinase
IOOILHMJ_00250 9e-170 glnL T Regulator
IOOILHMJ_00251 5e-173 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
IOOILHMJ_00252 6.9e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOOILHMJ_00253 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
IOOILHMJ_00254 9.4e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IOOILHMJ_00255 1.5e-124 ycbG K FCD
IOOILHMJ_00256 1.2e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
IOOILHMJ_00257 4.8e-176 ycbJ S Macrolide 2'-phosphotransferase
IOOILHMJ_00258 1.3e-23 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
IOOILHMJ_00259 4.1e-167 eamA1 EG spore germination
IOOILHMJ_00260 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_00261 1.4e-167 T PhoQ Sensor
IOOILHMJ_00262 1.1e-164 ycbN V ABC transporter, ATP-binding protein
IOOILHMJ_00263 9.6e-113 S ABC-2 family transporter protein
IOOILHMJ_00264 8.2e-53 ycbP S Protein of unknown function (DUF2512)
IOOILHMJ_00265 4.8e-78 sleB 3.5.1.28 M Cell wall
IOOILHMJ_00266 8.9e-133 ycbR T vWA found in TerF C terminus
IOOILHMJ_00267 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
IOOILHMJ_00268 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IOOILHMJ_00269 2.9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IOOILHMJ_00270 2.2e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOOILHMJ_00271 8.1e-202 ycbU E Selenocysteine lyase
IOOILHMJ_00272 5.8e-229 lmrB EGP the major facilitator superfamily
IOOILHMJ_00273 7e-101 yxaF K Transcriptional regulator
IOOILHMJ_00274 1.5e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IOOILHMJ_00275 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IOOILHMJ_00276 1.6e-56 S RDD family
IOOILHMJ_00277 2.1e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
IOOILHMJ_00278 1.5e-156 2.7.13.3 T GHKL domain
IOOILHMJ_00279 1.2e-126 lytR_2 T LytTr DNA-binding domain
IOOILHMJ_00280 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
IOOILHMJ_00281 3.5e-200 natB CP ABC-2 family transporter protein
IOOILHMJ_00282 3e-173 yccK C Aldo keto reductase
IOOILHMJ_00283 6.6e-177 ycdA S Domain of unknown function (DUF5105)
IOOILHMJ_00284 6.8e-270 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_00285 1.9e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_00286 2.7e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
IOOILHMJ_00287 6.1e-173 S response regulator aspartate phosphatase
IOOILHMJ_00288 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
IOOILHMJ_00289 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
IOOILHMJ_00290 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
IOOILHMJ_00291 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IOOILHMJ_00292 2.4e-134 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IOOILHMJ_00293 1.8e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOOILHMJ_00294 9.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
IOOILHMJ_00295 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
IOOILHMJ_00296 1.9e-106 yceE T proteins involved in stress response, homologs of TerZ and
IOOILHMJ_00297 6.3e-137 terC P Protein of unknown function (DUF475)
IOOILHMJ_00298 0.0 yceG S Putative component of 'biosynthetic module'
IOOILHMJ_00299 4.4e-192 yceH P Belongs to the TelA family
IOOILHMJ_00300 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
IOOILHMJ_00301 1.1e-204 yceJ EGP Uncharacterised MFS-type transporter YbfB
IOOILHMJ_00302 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOOILHMJ_00303 4.1e-226 proV 3.6.3.32 E glycine betaine
IOOILHMJ_00304 1.3e-127 opuAB P glycine betaine
IOOILHMJ_00305 1.2e-163 opuAC E glycine betaine
IOOILHMJ_00306 4.7e-213 amhX S amidohydrolase
IOOILHMJ_00307 8.7e-257 ycgA S Membrane
IOOILHMJ_00308 4.1e-81 ycgB
IOOILHMJ_00309 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
IOOILHMJ_00310 6.8e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOOILHMJ_00311 6.7e-290 lctP C L-lactate permease
IOOILHMJ_00312 4.3e-262 mdr EGP Major facilitator Superfamily
IOOILHMJ_00313 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
IOOILHMJ_00314 6.8e-113 ycgF E Lysine exporter protein LysE YggA
IOOILHMJ_00315 1.1e-146 yqcI S YqcI/YcgG family
IOOILHMJ_00316 1.3e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
IOOILHMJ_00317 2.1e-111 ycgI S Domain of unknown function (DUF1989)
IOOILHMJ_00318 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOOILHMJ_00319 1.2e-106 tmrB S AAA domain
IOOILHMJ_00321 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IOOILHMJ_00322 2.4e-141 yafE Q ubiE/COQ5 methyltransferase family
IOOILHMJ_00323 1.5e-175 oxyR3 K LysR substrate binding domain
IOOILHMJ_00324 3.6e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IOOILHMJ_00325 4.1e-144 ycgL S Predicted nucleotidyltransferase
IOOILHMJ_00326 2.5e-169 ycgM E Proline dehydrogenase
IOOILHMJ_00327 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IOOILHMJ_00328 2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOOILHMJ_00329 8e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
IOOILHMJ_00330 1.1e-145 ycgQ S membrane
IOOILHMJ_00331 2.9e-138 ycgR S permeases
IOOILHMJ_00332 1e-156 I alpha/beta hydrolase fold
IOOILHMJ_00333 7.1e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IOOILHMJ_00334 3.5e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IOOILHMJ_00335 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
IOOILHMJ_00336 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IOOILHMJ_00337 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOOILHMJ_00338 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
IOOILHMJ_00339 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
IOOILHMJ_00340 1.8e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
IOOILHMJ_00341 4.7e-108 yciB M ErfK YbiS YcfS YnhG
IOOILHMJ_00342 1e-226 yciC S GTPases (G3E family)
IOOILHMJ_00343 9.2e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
IOOILHMJ_00344 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IOOILHMJ_00346 7e-58 yckC S membrane
IOOILHMJ_00347 7.8e-52 yckD S Protein of unknown function (DUF2680)
IOOILHMJ_00348 3.4e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOOILHMJ_00349 3.6e-67 nin S Competence protein J (ComJ)
IOOILHMJ_00350 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
IOOILHMJ_00351 2.1e-185 tlpC 2.7.13.3 NT chemotaxis protein
IOOILHMJ_00352 1.1e-93 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
IOOILHMJ_00353 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
IOOILHMJ_00354 1.7e-63 hxlR K transcriptional
IOOILHMJ_00355 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_00356 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_00357 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
IOOILHMJ_00358 5.4e-138 srfAD Q thioesterase
IOOILHMJ_00359 2.2e-224 EGP Major Facilitator Superfamily
IOOILHMJ_00360 7.9e-89 S YcxB-like protein
IOOILHMJ_00361 1.7e-160 ycxC EG EamA-like transporter family
IOOILHMJ_00362 1.2e-249 ycxD K GntR family transcriptional regulator
IOOILHMJ_00363 6.1e-112 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IOOILHMJ_00364 9.7e-115 yczE S membrane
IOOILHMJ_00365 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IOOILHMJ_00366 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
IOOILHMJ_00367 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IOOILHMJ_00368 1.9e-161 bsdA K LysR substrate binding domain
IOOILHMJ_00369 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IOOILHMJ_00370 3.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IOOILHMJ_00371 4e-39 bsdD 4.1.1.61 S response to toxic substance
IOOILHMJ_00372 1e-81 yclD
IOOILHMJ_00373 7.1e-158 yclE 3.4.11.5 S Alpha beta hydrolase
IOOILHMJ_00374 4e-265 dtpT E amino acid peptide transporter
IOOILHMJ_00375 7.2e-306 yclG M Pectate lyase superfamily protein
IOOILHMJ_00377 5.9e-278 gerKA EG Spore germination protein
IOOILHMJ_00378 1.3e-224 gerKC S spore germination
IOOILHMJ_00379 4.5e-184 gerKB F Spore germination protein
IOOILHMJ_00380 7.3e-121 yclH P ABC transporter
IOOILHMJ_00381 1.3e-202 yclI V ABC transporter (permease) YclI
IOOILHMJ_00382 4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_00383 6.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOOILHMJ_00384 2e-70 S aspartate phosphatase
IOOILHMJ_00387 1e-227 lysC 2.7.2.4 E Belongs to the aspartokinase family
IOOILHMJ_00388 4.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_00389 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_00390 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
IOOILHMJ_00391 7.2e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
IOOILHMJ_00392 1.2e-250 ycnB EGP Major facilitator Superfamily
IOOILHMJ_00393 1.2e-152 ycnC K Transcriptional regulator
IOOILHMJ_00394 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
IOOILHMJ_00395 1.6e-45 ycnE S Monooxygenase
IOOILHMJ_00396 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
IOOILHMJ_00397 1.1e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOOILHMJ_00398 5.9e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOOILHMJ_00399 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOOILHMJ_00400 6.1e-149 glcU U Glucose uptake
IOOILHMJ_00401 4.6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_00402 7.8e-98 ycnI S protein conserved in bacteria
IOOILHMJ_00403 1.9e-305 ycnJ P protein, homolog of Cu resistance protein CopC
IOOILHMJ_00404 6.2e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
IOOILHMJ_00405 4.4e-53
IOOILHMJ_00406 4.8e-239 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
IOOILHMJ_00407 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IOOILHMJ_00408 2e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
IOOILHMJ_00409 6.5e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
IOOILHMJ_00410 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IOOILHMJ_00411 7.1e-74 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IOOILHMJ_00412 9.1e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
IOOILHMJ_00413 2.1e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IOOILHMJ_00415 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IOOILHMJ_00416 2e-138 ycsF S Belongs to the UPF0271 (lamB) family
IOOILHMJ_00417 3.2e-212 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
IOOILHMJ_00418 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
IOOILHMJ_00419 1e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
IOOILHMJ_00420 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
IOOILHMJ_00421 3e-131 kipR K Transcriptional regulator
IOOILHMJ_00422 9.4e-115 ycsK E anatomical structure formation involved in morphogenesis
IOOILHMJ_00424 1.4e-49 yczJ S biosynthesis
IOOILHMJ_00425 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
IOOILHMJ_00426 2.1e-171 ydhF S Oxidoreductase
IOOILHMJ_00427 0.0 mtlR K transcriptional regulator, MtlR
IOOILHMJ_00428 5.3e-289 ydaB IQ acyl-CoA ligase
IOOILHMJ_00429 6.9e-99 ydaC Q Methyltransferase domain
IOOILHMJ_00430 9.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_00431 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
IOOILHMJ_00432 7.3e-95 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOOILHMJ_00433 2.6e-76 ydaG 1.4.3.5 S general stress protein
IOOILHMJ_00434 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IOOILHMJ_00435 3.3e-46 ydzA EGP Major facilitator Superfamily
IOOILHMJ_00436 2.5e-74 lrpC K Transcriptional regulator
IOOILHMJ_00437 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOOILHMJ_00438 4.9e-204 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
IOOILHMJ_00439 2.3e-148 ydaK T Diguanylate cyclase, GGDEF domain
IOOILHMJ_00440 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
IOOILHMJ_00441 4.5e-233 ydaM M Glycosyl transferase family group 2
IOOILHMJ_00442 0.0 ydaN S Bacterial cellulose synthase subunit
IOOILHMJ_00443 0.0 ydaO E amino acid
IOOILHMJ_00444 9.6e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IOOILHMJ_00445 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOOILHMJ_00446 9.4e-40
IOOILHMJ_00447 1.7e-224 mntH P H( )-stimulated, divalent metal cation uptake system
IOOILHMJ_00449 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
IOOILHMJ_00450 1.6e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
IOOILHMJ_00452 3.1e-56 ydbB G Cupin domain
IOOILHMJ_00453 4.5e-61 ydbC S Domain of unknown function (DUF4937
IOOILHMJ_00454 7.9e-154 ydbD P Catalase
IOOILHMJ_00455 2.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IOOILHMJ_00456 2.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IOOILHMJ_00457 3.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
IOOILHMJ_00458 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOOILHMJ_00459 4.4e-181 ydbI S AI-2E family transporter
IOOILHMJ_00460 3e-170 ydbJ V ABC transporter, ATP-binding protein
IOOILHMJ_00461 2.7e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOOILHMJ_00462 2.7e-52 ydbL
IOOILHMJ_00463 1.7e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
IOOILHMJ_00464 5.6e-18 S Fur-regulated basic protein B
IOOILHMJ_00465 2.2e-07 S Fur-regulated basic protein A
IOOILHMJ_00466 1.3e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOOILHMJ_00467 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IOOILHMJ_00468 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IOOILHMJ_00469 1.9e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOOILHMJ_00470 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOOILHMJ_00471 1.4e-81 ydbS S Bacterial PH domain
IOOILHMJ_00472 8.6e-260 ydbT S Membrane
IOOILHMJ_00473 5.3e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
IOOILHMJ_00474 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOOILHMJ_00475 5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
IOOILHMJ_00476 2.8e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOOILHMJ_00477 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IOOILHMJ_00478 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
IOOILHMJ_00479 1.3e-143 rsbR T Positive regulator of sigma-B
IOOILHMJ_00480 5.2e-57 rsbS T antagonist
IOOILHMJ_00481 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IOOILHMJ_00482 7.1e-189 rsbU 3.1.3.3 KT phosphatase
IOOILHMJ_00483 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
IOOILHMJ_00484 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IOOILHMJ_00485 4.5e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOOILHMJ_00486 2.4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
IOOILHMJ_00487 2.3e-16 J glyoxalase III activity
IOOILHMJ_00488 1.5e-82 ydcG S EVE domain
IOOILHMJ_00489 3.9e-75 ydcH K helix_turn_helix multiple antibiotic resistance protein
IOOILHMJ_00490 0.0 yhgF K COG2183 Transcriptional accessory protein
IOOILHMJ_00491 8.9e-83 ydcK S Belongs to the SprT family
IOOILHMJ_00502 1.3e-157 KLT Protein kinase domain
IOOILHMJ_00509 3.6e-213 KLT Protein kinase domain
IOOILHMJ_00510 3.4e-207 msbA2 3.6.3.44 V ABC transporter
IOOILHMJ_00511 7.2e-46 ydeH
IOOILHMJ_00512 1.4e-09 E PFAM Glyoxalase bleomycin resistance protein dioxygenase
IOOILHMJ_00513 9.8e-33 K Helix-turn-helix XRE-family like proteins
IOOILHMJ_00514 1.2e-39
IOOILHMJ_00515 7.5e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IOOILHMJ_00516 8.7e-30 cspL K Cold shock
IOOILHMJ_00517 6.8e-78 carD K Transcription factor
IOOILHMJ_00518 5.5e-161 rhaS5 K AraC-like ligand binding domain
IOOILHMJ_00519 1.1e-167 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOOILHMJ_00520 1.5e-163 ydeE K AraC family transcriptional regulator
IOOILHMJ_00521 7.8e-255 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOOILHMJ_00522 3.2e-210 ydeG EGP Major facilitator superfamily
IOOILHMJ_00523 3e-44 ydeH
IOOILHMJ_00524 4.9e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
IOOILHMJ_00525 6.9e-108
IOOILHMJ_00526 1.7e-151 ydeK EG -transporter
IOOILHMJ_00527 7.1e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOOILHMJ_00528 4.2e-74 maoC I N-terminal half of MaoC dehydratase
IOOILHMJ_00529 1.7e-102 ydeN S Serine hydrolase
IOOILHMJ_00530 7.5e-55 K HxlR-like helix-turn-helix
IOOILHMJ_00531 3.6e-149 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IOOILHMJ_00532 4.8e-69 ydeP K Transcriptional regulator
IOOILHMJ_00533 5.1e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
IOOILHMJ_00534 5.2e-191 ydeR EGP Major facilitator Superfamily
IOOILHMJ_00535 3.2e-104 ydeS K Transcriptional regulator
IOOILHMJ_00537 2.8e-57 arsR K transcriptional
IOOILHMJ_00538 2.2e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IOOILHMJ_00539 1e-142 ydfB J GNAT acetyltransferase
IOOILHMJ_00540 1e-146 lytR K Transcriptional regulator
IOOILHMJ_00541 1.6e-122 nodB1 G deacetylase
IOOILHMJ_00542 9.6e-158
IOOILHMJ_00543 1.3e-212 T GHKL domain
IOOILHMJ_00544 1.3e-121 T Transcriptional regulatory protein, C terminal
IOOILHMJ_00545 9.9e-150 ydfC EG EamA-like transporter family
IOOILHMJ_00546 8.7e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOOILHMJ_00547 2.7e-114 ydfE S Flavin reductase like domain
IOOILHMJ_00548 5e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
IOOILHMJ_00549 7.7e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IOOILHMJ_00551 5.2e-178 ydfH 2.7.13.3 T Histidine kinase
IOOILHMJ_00552 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOOILHMJ_00553 0.0 ydfJ S drug exporters of the RND superfamily
IOOILHMJ_00554 5.8e-174 S Alpha/beta hydrolase family
IOOILHMJ_00555 9.3e-116 S Protein of unknown function (DUF554)
IOOILHMJ_00556 4.6e-146 K Bacterial transcription activator, effector binding domain
IOOILHMJ_00557 5e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOOILHMJ_00558 6.9e-110 ydfN C nitroreductase
IOOILHMJ_00559 2.6e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
IOOILHMJ_00560 8.8e-63 mhqP S DoxX
IOOILHMJ_00561 1.8e-56 traF CO Thioredoxin
IOOILHMJ_00562 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
IOOILHMJ_00563 4.4e-30
IOOILHMJ_00565 4.9e-109 ydfR S Protein of unknown function (DUF421)
IOOILHMJ_00566 4.7e-83 ydfS S Protein of unknown function (DUF421)
IOOILHMJ_00567 7.3e-66 cotP O Belongs to the small heat shock protein (HSP20) family
IOOILHMJ_00568 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
IOOILHMJ_00569 2.5e-32 ydgB S Spore germination protein gerPA/gerPF
IOOILHMJ_00570 4.5e-98 K Bacterial regulatory proteins, tetR family
IOOILHMJ_00571 6.2e-52 S DoxX-like family
IOOILHMJ_00572 1e-84 yycN 2.3.1.128 K Acetyltransferase
IOOILHMJ_00573 9.8e-47 FG HIT domain
IOOILHMJ_00574 2.3e-138 EGP Major facilitator Superfamily
IOOILHMJ_00575 1.2e-49 K Transcriptional regulator
IOOILHMJ_00576 6.7e-290 expZ S ABC transporter
IOOILHMJ_00577 2e-250 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
IOOILHMJ_00578 2.1e-88 dinB S DinB family
IOOILHMJ_00579 1.6e-79 K helix_turn_helix multiple antibiotic resistance protein
IOOILHMJ_00580 0.0 ydgH S drug exporters of the RND superfamily
IOOILHMJ_00581 1e-113 drgA C nitroreductase
IOOILHMJ_00582 7.1e-69 ydgJ K Winged helix DNA-binding domain
IOOILHMJ_00583 6.3e-208 tcaB EGP Major facilitator Superfamily
IOOILHMJ_00584 4.6e-121 ydhB S membrane transporter protein
IOOILHMJ_00585 1e-119 ydhC K FCD
IOOILHMJ_00586 6.5e-240 ydhD M Glycosyl hydrolase
IOOILHMJ_00587 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IOOILHMJ_00588 4.3e-124
IOOILHMJ_00589 1.5e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IOOILHMJ_00590 1.1e-65 frataxin S Domain of unknown function (DU1801)
IOOILHMJ_00592 2.3e-81 K Acetyltransferase (GNAT) domain
IOOILHMJ_00593 1.5e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOOILHMJ_00594 6.1e-97 ydhK M Protein of unknown function (DUF1541)
IOOILHMJ_00595 4.6e-200 pbuE EGP Major facilitator Superfamily
IOOILHMJ_00596 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
IOOILHMJ_00597 1.3e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
IOOILHMJ_00598 7.5e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOOILHMJ_00599 5.6e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOOILHMJ_00600 1.2e-129 ydhQ K UTRA
IOOILHMJ_00601 8.9e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
IOOILHMJ_00602 4.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
IOOILHMJ_00603 4.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
IOOILHMJ_00604 6.1e-157 ydhU P Catalase
IOOILHMJ_00607 3.4e-39 S COG NOG14552 non supervised orthologous group
IOOILHMJ_00608 7.8e-08
IOOILHMJ_00610 1.2e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IOOILHMJ_00611 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
IOOILHMJ_00612 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
IOOILHMJ_00613 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IOOILHMJ_00614 2.3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOOILHMJ_00615 0.0 ydiF S ABC transporter
IOOILHMJ_00616 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IOOILHMJ_00617 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOOILHMJ_00618 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IOOILHMJ_00619 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IOOILHMJ_00620 2.9e-27 ydiK S Domain of unknown function (DUF4305)
IOOILHMJ_00621 1.1e-127 ydiL S CAAX protease self-immunity
IOOILHMJ_00622 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOOILHMJ_00623 6.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOOILHMJ_00624 2.4e-152 ydjC S Abhydrolase domain containing 18
IOOILHMJ_00625 0.0 K NB-ARC domain
IOOILHMJ_00626 4.2e-200 gutB 1.1.1.14 E Dehydrogenase
IOOILHMJ_00627 2.1e-252 gutA G MFS/sugar transport protein
IOOILHMJ_00628 2.7e-169 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
IOOILHMJ_00629 7.3e-113 pspA KT Phage shock protein A
IOOILHMJ_00630 1.1e-176 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOOILHMJ_00631 2.2e-134 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
IOOILHMJ_00632 1.7e-147 ydjI S virion core protein (lumpy skin disease virus)
IOOILHMJ_00633 4.7e-196 S Ion transport 2 domain protein
IOOILHMJ_00634 5e-257 iolT EGP Major facilitator Superfamily
IOOILHMJ_00635 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
IOOILHMJ_00636 4.5e-64 ydjM M Lytic transglycolase
IOOILHMJ_00637 1.2e-151 ydjN U Involved in the tonB-independent uptake of proteins
IOOILHMJ_00639 1.4e-34 ydjO S Cold-inducible protein YdjO
IOOILHMJ_00640 2.1e-154 ydjP I Alpha/beta hydrolase family
IOOILHMJ_00641 6.8e-176 yeaA S Protein of unknown function (DUF4003)
IOOILHMJ_00642 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
IOOILHMJ_00643 1.3e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
IOOILHMJ_00644 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOOILHMJ_00645 1e-173 yeaC S COG0714 MoxR-like ATPases
IOOILHMJ_00646 4e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IOOILHMJ_00647 0.0 yebA E COG1305 Transglutaminase-like enzymes
IOOILHMJ_00648 2.4e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IOOILHMJ_00649 2.7e-86 K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_00650 4.9e-255 S Domain of unknown function (DUF4179)
IOOILHMJ_00651 6.6e-211 pbuG S permease
IOOILHMJ_00652 4.4e-117 yebC M Membrane
IOOILHMJ_00654 8.9e-93 yebE S UPF0316 protein
IOOILHMJ_00655 8e-28 yebG S NETI protein
IOOILHMJ_00656 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOOILHMJ_00657 2.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOOILHMJ_00658 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOOILHMJ_00659 1.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IOOILHMJ_00660 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOOILHMJ_00661 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOOILHMJ_00662 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOOILHMJ_00663 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOOILHMJ_00664 9.3e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IOOILHMJ_00665 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOOILHMJ_00666 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IOOILHMJ_00667 1e-232 purD 6.3.4.13 F Belongs to the GARS family
IOOILHMJ_00668 5e-72 K helix_turn_helix ASNC type
IOOILHMJ_00669 6.4e-227 yjeH E Amino acid permease
IOOILHMJ_00670 2.7e-27 S Protein of unknown function (DUF2892)
IOOILHMJ_00671 0.0 yerA 3.5.4.2 F adenine deaminase
IOOILHMJ_00672 1.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
IOOILHMJ_00673 4.8e-51 yerC S protein conserved in bacteria
IOOILHMJ_00674 1.4e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
IOOILHMJ_00676 2.7e-123 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IOOILHMJ_00677 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IOOILHMJ_00678 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOOILHMJ_00679 2.7e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
IOOILHMJ_00680 2e-196 yerI S homoserine kinase type II (protein kinase fold)
IOOILHMJ_00681 1.6e-123 sapB S MgtC SapB transporter
IOOILHMJ_00682 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOOILHMJ_00683 3.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOOILHMJ_00684 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOOILHMJ_00685 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOOILHMJ_00686 1.3e-148 yerO K Transcriptional regulator
IOOILHMJ_00687 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IOOILHMJ_00688 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IOOILHMJ_00689 3.3e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOOILHMJ_00690 3.6e-36 K Wd-40 repeat
IOOILHMJ_00691 1.6e-17
IOOILHMJ_00692 3.1e-115 S Uncharacterised protein conserved in bacteria (DUF2326)
IOOILHMJ_00693 3.6e-119
IOOILHMJ_00694 7.1e-53 V Domain of unknown function (DUF3578)
IOOILHMJ_00696 1e-26
IOOILHMJ_00698 9.5e-37 S Protein of unknown function, DUF600
IOOILHMJ_00699 6.6e-84 S Protein of unknown function, DUF600
IOOILHMJ_00700 0.0 L nucleic acid phosphodiester bond hydrolysis
IOOILHMJ_00702 5.6e-100 L endonuclease activity
IOOILHMJ_00703 1.2e-51
IOOILHMJ_00704 2.6e-208 S Tetratricopeptide repeat
IOOILHMJ_00706 9.4e-127 yeeN K transcriptional regulatory protein
IOOILHMJ_00708 2.7e-100 dhaR3 K Transcriptional regulator
IOOILHMJ_00709 9.1e-80 yesE S SnoaL-like domain
IOOILHMJ_00710 4.3e-147 yesF GM NAD(P)H-binding
IOOILHMJ_00711 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
IOOILHMJ_00712 1.5e-45 cotJB S CotJB protein
IOOILHMJ_00713 5.2e-104 cotJC P Spore Coat
IOOILHMJ_00714 6e-102 yesJ K Acetyltransferase (GNAT) family
IOOILHMJ_00716 5.5e-99 yesL S Protein of unknown function, DUF624
IOOILHMJ_00717 0.0 yesM 2.7.13.3 T Histidine kinase
IOOILHMJ_00718 3e-201 yesN K helix_turn_helix, arabinose operon control protein
IOOILHMJ_00719 2.8e-246 yesO G Bacterial extracellular solute-binding protein
IOOILHMJ_00720 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
IOOILHMJ_00721 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
IOOILHMJ_00722 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
IOOILHMJ_00723 0.0 yesS K Transcriptional regulator
IOOILHMJ_00724 5.1e-130 E GDSL-like Lipase/Acylhydrolase
IOOILHMJ_00725 2.1e-128 yesU S Domain of unknown function (DUF1961)
IOOILHMJ_00726 3.3e-112 yesV S Protein of unknown function, DUF624
IOOILHMJ_00727 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
IOOILHMJ_00728 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
IOOILHMJ_00729 3.4e-123 yesY E GDSL-like Lipase/Acylhydrolase
IOOILHMJ_00730 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
IOOILHMJ_00731 0.0 yetA
IOOILHMJ_00732 6.2e-290 lplA G Bacterial extracellular solute-binding protein
IOOILHMJ_00733 5.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
IOOILHMJ_00734 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
IOOILHMJ_00735 7.1e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IOOILHMJ_00736 8.8e-122 yetF S membrane
IOOILHMJ_00737 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IOOILHMJ_00738 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOOILHMJ_00739 2.2e-34
IOOILHMJ_00740 9.3e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOOILHMJ_00741 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
IOOILHMJ_00742 5.3e-105 yetJ S Belongs to the BI1 family
IOOILHMJ_00743 1.6e-29 yetM CH FAD binding domain
IOOILHMJ_00744 8e-199 yetN S Protein of unknown function (DUF3900)
IOOILHMJ_00745 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IOOILHMJ_00746 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IOOILHMJ_00747 1.1e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
IOOILHMJ_00748 1.9e-172 yfnG 4.2.1.45 M dehydratase
IOOILHMJ_00749 2.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
IOOILHMJ_00750 2.1e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
IOOILHMJ_00751 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
IOOILHMJ_00752 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
IOOILHMJ_00753 1.5e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOOILHMJ_00754 6.4e-241 yfnA E amino acid
IOOILHMJ_00755 1.8e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOOILHMJ_00756 1.1e-113 yfmS NT chemotaxis protein
IOOILHMJ_00757 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOOILHMJ_00758 4e-75 yfmQ S Uncharacterised protein from bacillus cereus group
IOOILHMJ_00759 2.4e-69 yfmP K transcriptional
IOOILHMJ_00760 9.5e-209 yfmO EGP Major facilitator Superfamily
IOOILHMJ_00761 7.2e-08 yhfO K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOOILHMJ_00762 6.3e-73
IOOILHMJ_00763 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOOILHMJ_00764 5.9e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
IOOILHMJ_00765 7e-72 yfmK 2.3.1.128 K acetyltransferase
IOOILHMJ_00766 2.3e-187 yfmJ S N-terminal domain of oxidoreductase
IOOILHMJ_00767 3.3e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
IOOILHMJ_00768 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_00769 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_00770 3.2e-167 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IOOILHMJ_00771 2.9e-24 S Protein of unknown function (DUF3212)
IOOILHMJ_00772 1.7e-57 yflT S Heat induced stress protein YflT
IOOILHMJ_00773 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
IOOILHMJ_00774 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
IOOILHMJ_00775 6.5e-285 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IOOILHMJ_00776 3.4e-118 citT T response regulator
IOOILHMJ_00777 2.3e-176 yflP S Tripartite tricarboxylate transporter family receptor
IOOILHMJ_00778 8.5e-227 citM C Citrate transporter
IOOILHMJ_00779 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
IOOILHMJ_00780 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IOOILHMJ_00781 9.4e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IOOILHMJ_00782 6.4e-122 yflK S protein conserved in bacteria
IOOILHMJ_00783 8.9e-18 yflJ S Protein of unknown function (DUF2639)
IOOILHMJ_00784 4.1e-19 yflI
IOOILHMJ_00785 9.1e-50 yflH S Protein of unknown function (DUF3243)
IOOILHMJ_00786 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
IOOILHMJ_00787 7.4e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IOOILHMJ_00788 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IOOILHMJ_00789 6e-67 yhdN S Domain of unknown function (DUF1992)
IOOILHMJ_00790 2.2e-252 agcS_1 E Sodium alanine symporter
IOOILHMJ_00791 3.5e-194 E Spore germination protein
IOOILHMJ_00793 1.2e-205 yfkR S spore germination
IOOILHMJ_00794 5.4e-281 yfkQ EG Spore germination protein
IOOILHMJ_00795 2.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOOILHMJ_00796 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IOOILHMJ_00797 1.8e-133 treR K transcriptional
IOOILHMJ_00798 1.1e-124 yfkO C nitroreductase
IOOILHMJ_00799 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IOOILHMJ_00800 2.4e-87 yfkM 1.11.1.6, 3.5.1.124 S protease
IOOILHMJ_00801 2.9e-205 ydiM EGP Major facilitator Superfamily
IOOILHMJ_00802 1.3e-28 yfkK S Belongs to the UPF0435 family
IOOILHMJ_00803 5.5e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOOILHMJ_00804 2.4e-50 yfkI S gas vesicle protein
IOOILHMJ_00805 1.3e-143 yihY S Belongs to the UPF0761 family
IOOILHMJ_00806 5e-08
IOOILHMJ_00807 1.3e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
IOOILHMJ_00808 6.1e-183 cax P COG0387 Ca2 H antiporter
IOOILHMJ_00809 1.2e-146 yfkD S YfkD-like protein
IOOILHMJ_00810 6e-149 yfkC M Mechanosensitive ion channel
IOOILHMJ_00811 5.4e-222 yfkA S YfkB-like domain
IOOILHMJ_00812 1.1e-26 yfjT
IOOILHMJ_00813 1.3e-153 pdaA G deacetylase
IOOILHMJ_00814 2.3e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IOOILHMJ_00815 1.7e-184 corA P Mediates influx of magnesium ions
IOOILHMJ_00816 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IOOILHMJ_00817 1.2e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOOILHMJ_00818 8.8e-44 S YfzA-like protein
IOOILHMJ_00819 2.4e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOOILHMJ_00820 4.3e-85 yfjM S Psort location Cytoplasmic, score
IOOILHMJ_00822 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOOILHMJ_00823 8.5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOOILHMJ_00824 5.6e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOOILHMJ_00825 1.1e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOOILHMJ_00826 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
IOOILHMJ_00827 4.9e-24 sspH S Belongs to the SspH family
IOOILHMJ_00828 4e-56 yfjF S UPF0060 membrane protein
IOOILHMJ_00829 1.8e-101 yfjD S Family of unknown function (DUF5381)
IOOILHMJ_00830 2e-143 yfjC
IOOILHMJ_00831 2.7e-190 yfjB
IOOILHMJ_00832 1.1e-44 yfjA S Belongs to the WXG100 family
IOOILHMJ_00833 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IOOILHMJ_00834 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
IOOILHMJ_00835 1.8e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOOILHMJ_00836 4.9e-307 yfiB3 V ABC transporter
IOOILHMJ_00837 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
IOOILHMJ_00838 6.4e-64 mhqP S DoxX
IOOILHMJ_00839 1.1e-161 yfiE 1.13.11.2 S glyoxalase
IOOILHMJ_00840 7.7e-187 yxjM T Histidine kinase
IOOILHMJ_00841 2.3e-111 KT LuxR family transcriptional regulator
IOOILHMJ_00842 1.5e-164 V ABC transporter, ATP-binding protein
IOOILHMJ_00843 9.8e-206 V ABC-2 family transporter protein
IOOILHMJ_00844 3.2e-201 V COG0842 ABC-type multidrug transport system, permease component
IOOILHMJ_00845 3.1e-67 J Acetyltransferase (GNAT) domain
IOOILHMJ_00846 7e-98 padR K transcriptional
IOOILHMJ_00847 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IOOILHMJ_00848 7.1e-65 K Bacterial regulatory proteins, tetR family
IOOILHMJ_00849 6.7e-60 GM NADH-flavin reductase
IOOILHMJ_00850 9.9e-90 ybhR V COG0842 ABC-type multidrug transport system, permease component
IOOILHMJ_00851 2.1e-78 ybhF_2 V COG1131 ABC-type multidrug transport system, ATPase component
IOOILHMJ_00852 1e-188 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IOOILHMJ_00853 9.6e-104 yfiR K Transcriptional regulator
IOOILHMJ_00854 3.7e-211 yfiS EGP Major facilitator Superfamily
IOOILHMJ_00855 6.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
IOOILHMJ_00856 7.6e-283 yfiU EGP Major facilitator Superfamily
IOOILHMJ_00857 1.4e-78 yfiV K transcriptional
IOOILHMJ_00858 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOOILHMJ_00859 2.8e-174 yfiY P ABC transporter substrate-binding protein
IOOILHMJ_00860 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_00861 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_00862 1.8e-164 yfhB 5.3.3.17 S PhzF family
IOOILHMJ_00863 1.3e-105 yfhC C nitroreductase
IOOILHMJ_00864 2.1e-25 yfhD S YfhD-like protein
IOOILHMJ_00866 2.1e-171 yfhF S nucleoside-diphosphate sugar epimerase
IOOILHMJ_00867 8.2e-140 recX 2.4.1.337 GT4 S Modulates RecA activity
IOOILHMJ_00868 2.4e-50 yfhH S Protein of unknown function (DUF1811)
IOOILHMJ_00870 4.7e-208 yfhI EGP Major facilitator Superfamily
IOOILHMJ_00871 6.2e-20 sspK S reproduction
IOOILHMJ_00872 1.3e-44 yfhJ S WVELL protein
IOOILHMJ_00873 2.4e-87 batE T Bacterial SH3 domain homologues
IOOILHMJ_00874 1e-50 yfhL S SdpI/YhfL protein family
IOOILHMJ_00875 4.1e-169 yfhM S Alpha beta hydrolase
IOOILHMJ_00876 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IOOILHMJ_00877 0.0 yfhO S Bacterial membrane protein YfhO
IOOILHMJ_00878 1.2e-185 yfhP S membrane-bound metal-dependent
IOOILHMJ_00879 2.1e-209 mutY L A G-specific
IOOILHMJ_00880 6.9e-36 yfhS
IOOILHMJ_00881 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_00882 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
IOOILHMJ_00883 4.9e-48 ygaB S YgaB-like protein
IOOILHMJ_00884 1.3e-104 ygaC J Belongs to the UPF0374 family
IOOILHMJ_00885 3.5e-300 ygaD V ABC transporter
IOOILHMJ_00886 4.7e-178 ygaE S Membrane
IOOILHMJ_00887 9.9e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IOOILHMJ_00888 4.1e-86 bcp 1.11.1.15 O Peroxiredoxin
IOOILHMJ_00889 4e-80 perR P Belongs to the Fur family
IOOILHMJ_00890 2.8e-55 ygzB S UPF0295 protein
IOOILHMJ_00891 6.7e-167 ygxA S Nucleotidyltransferase-like
IOOILHMJ_00892 3.4e-39 S COG NOG14552 non supervised orthologous group
IOOILHMJ_00897 7.8e-08
IOOILHMJ_00905 2e-08
IOOILHMJ_00909 5.9e-143 spo0M S COG4326 Sporulation control protein
IOOILHMJ_00910 1.2e-26
IOOILHMJ_00911 1e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
IOOILHMJ_00913 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IOOILHMJ_00915 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IOOILHMJ_00916 1.9e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IOOILHMJ_00917 6.2e-169 ssuA M Sulfonate ABC transporter
IOOILHMJ_00918 9.4e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IOOILHMJ_00919 4.9e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
IOOILHMJ_00920 2.3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOOILHMJ_00921 2.6e-77 ygaO
IOOILHMJ_00922 4.4e-29 K Transcriptional regulator
IOOILHMJ_00924 7.7e-109 yhzB S B3/4 domain
IOOILHMJ_00925 3.3e-222 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IOOILHMJ_00926 2.4e-175 yhbB S Putative amidase domain
IOOILHMJ_00927 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOOILHMJ_00928 3.3e-107 yhbD K Protein of unknown function (DUF4004)
IOOILHMJ_00929 3.9e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
IOOILHMJ_00930 3.2e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
IOOILHMJ_00931 0.0 prkA T Ser protein kinase
IOOILHMJ_00932 2.5e-225 yhbH S Belongs to the UPF0229 family
IOOILHMJ_00933 2.2e-76 yhbI K DNA-binding transcription factor activity
IOOILHMJ_00934 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
IOOILHMJ_00935 3.1e-271 yhcA EGP Major facilitator Superfamily
IOOILHMJ_00936 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
IOOILHMJ_00937 3.6e-37 yhcC
IOOILHMJ_00938 5e-54
IOOILHMJ_00939 1.9e-59 yhcF K Transcriptional regulator
IOOILHMJ_00940 2.6e-121 yhcG V ABC transporter, ATP-binding protein
IOOILHMJ_00941 1.7e-165 yhcH V ABC transporter, ATP-binding protein
IOOILHMJ_00942 1.1e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOOILHMJ_00943 1e-30 cspB K Cold-shock protein
IOOILHMJ_00944 4.1e-150 metQ M Belongs to the nlpA lipoprotein family
IOOILHMJ_00945 1.3e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
IOOILHMJ_00946 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOOILHMJ_00947 3.2e-40 yhcM
IOOILHMJ_00948 1.7e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOOILHMJ_00949 1.4e-165 yhcP
IOOILHMJ_00950 5.2e-100 yhcQ M Spore coat protein
IOOILHMJ_00951 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
IOOILHMJ_00952 3.5e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
IOOILHMJ_00953 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOOILHMJ_00954 1.3e-66 yhcU S Family of unknown function (DUF5365)
IOOILHMJ_00955 9.9e-68 yhcV S COG0517 FOG CBS domain
IOOILHMJ_00956 2.5e-118 yhcW 5.4.2.6 S hydrolase
IOOILHMJ_00957 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IOOILHMJ_00958 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOOILHMJ_00959 3.4e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IOOILHMJ_00960 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
IOOILHMJ_00961 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOOILHMJ_00962 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IOOILHMJ_00963 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IOOILHMJ_00964 3e-212 yhcY 2.7.13.3 T Histidine kinase
IOOILHMJ_00965 1.1e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOOILHMJ_00966 6.7e-82 azr 1.7.1.6 S NADPH-dependent FMN reductase
IOOILHMJ_00967 4.7e-38 yhdB S YhdB-like protein
IOOILHMJ_00968 1.8e-53 yhdC S Protein of unknown function (DUF3889)
IOOILHMJ_00969 4.3e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IOOILHMJ_00970 1e-75 nsrR K Transcriptional regulator
IOOILHMJ_00971 3.8e-199 L COG3666 Transposase and inactivated derivatives
IOOILHMJ_00972 1.4e-236 ygxB M Conserved TM helix
IOOILHMJ_00973 2.1e-276 ycgB S Stage V sporulation protein R
IOOILHMJ_00974 5e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IOOILHMJ_00975 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IOOILHMJ_00976 3.8e-162 citR K Transcriptional regulator
IOOILHMJ_00977 2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
IOOILHMJ_00978 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_00979 2.2e-249 yhdG E amino acid
IOOILHMJ_00980 5.7e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IOOILHMJ_00981 7.7e-266 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOOILHMJ_00982 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOOILHMJ_00983 8.1e-45 yhdK S Sigma-M inhibitor protein
IOOILHMJ_00984 6.6e-201 yhdL S Sigma factor regulator N-terminal
IOOILHMJ_00985 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_00986 7.5e-191 yhdN C Aldo keto reductase
IOOILHMJ_00987 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IOOILHMJ_00988 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IOOILHMJ_00989 1.2e-73 cueR K transcriptional
IOOILHMJ_00990 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
IOOILHMJ_00991 2.3e-238 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
IOOILHMJ_00992 2.7e-42 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOOILHMJ_00993 6.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOOILHMJ_00994 4e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOOILHMJ_00996 9.9e-184 yhdY M Mechanosensitive ion channel
IOOILHMJ_00997 1.4e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IOOILHMJ_00998 1.1e-147 yheN G deacetylase
IOOILHMJ_00999 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IOOILHMJ_01000 1.6e-228 nhaC C Na H antiporter
IOOILHMJ_01001 1.9e-82 nhaX T Belongs to the universal stress protein A family
IOOILHMJ_01003 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
IOOILHMJ_01004 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
IOOILHMJ_01005 6.5e-108 yheG GM NAD(P)H-binding
IOOILHMJ_01006 6.3e-28 sspB S spore protein
IOOILHMJ_01007 1.3e-36 yheE S Family of unknown function (DUF5342)
IOOILHMJ_01009 1.4e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
IOOILHMJ_01010 7.4e-216 yheC HJ YheC/D like ATP-grasp
IOOILHMJ_01011 2e-200 yheB S Belongs to the UPF0754 family
IOOILHMJ_01012 9.5e-48 yheA S Belongs to the UPF0342 family
IOOILHMJ_01013 3.2e-203 yhaZ L DNA alkylation repair enzyme
IOOILHMJ_01014 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
IOOILHMJ_01015 2.3e-292 hemZ H coproporphyrinogen III oxidase
IOOILHMJ_01016 1.3e-205 yhaU P COG0475 Kef-type K transport systems, membrane components
IOOILHMJ_01017 1.3e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
IOOILHMJ_01019 6e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
IOOILHMJ_01020 1.1e-26 S YhzD-like protein
IOOILHMJ_01021 6.8e-167 yhaQ S ABC transporter, ATP-binding protein
IOOILHMJ_01022 9.4e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
IOOILHMJ_01023 1.1e-220 yhaO L DNA repair exonuclease
IOOILHMJ_01024 0.0 yhaN L AAA domain
IOOILHMJ_01025 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
IOOILHMJ_01026 1.6e-21 yhaL S Sporulation protein YhaL
IOOILHMJ_01027 4.2e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOOILHMJ_01028 3.3e-89 yhaK S Putative zincin peptidase
IOOILHMJ_01029 1.3e-54 yhaI S Protein of unknown function (DUF1878)
IOOILHMJ_01030 1e-113 hpr K Negative regulator of protease production and sporulation
IOOILHMJ_01031 8.2e-39 yhaH S YtxH-like protein
IOOILHMJ_01032 5.4e-21
IOOILHMJ_01033 5.3e-79 trpP S Tryptophan transporter TrpP
IOOILHMJ_01034 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOOILHMJ_01035 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IOOILHMJ_01036 4.6e-137 ecsA V transporter (ATP-binding protein)
IOOILHMJ_01037 1.6e-214 ecsB U ABC transporter
IOOILHMJ_01038 1.3e-112 ecsC S EcsC protein family
IOOILHMJ_01039 1.6e-227 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IOOILHMJ_01040 1.3e-244 yhfA C membrane
IOOILHMJ_01041 6e-33 1.15.1.2 C Rubrerythrin
IOOILHMJ_01042 1.9e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IOOILHMJ_01043 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IOOILHMJ_01044 3.1e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IOOILHMJ_01045 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IOOILHMJ_01046 1.2e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IOOILHMJ_01047 5.4e-101 yhgD K Transcriptional regulator
IOOILHMJ_01048 1.3e-214 yhgE S YhgE Pip N-terminal domain protein
IOOILHMJ_01049 6.7e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOOILHMJ_01050 1.4e-136 yhfC S Putative membrane peptidase family (DUF2324)
IOOILHMJ_01051 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
IOOILHMJ_01052 4.1e-71 3.4.13.21 S ASCH
IOOILHMJ_01053 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOOILHMJ_01054 8.9e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IOOILHMJ_01055 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
IOOILHMJ_01056 5e-111 yhfK GM NmrA-like family
IOOILHMJ_01057 4.5e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IOOILHMJ_01058 7.4e-65 yhfM
IOOILHMJ_01059 8e-238 yhfN 3.4.24.84 O Peptidase M48
IOOILHMJ_01060 7.5e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
IOOILHMJ_01061 9.5e-47 VY92_01935 K acetyltransferase
IOOILHMJ_01062 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
IOOILHMJ_01063 1.4e-154 yfmC M Periplasmic binding protein
IOOILHMJ_01064 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IOOILHMJ_01065 1.4e-195 vraB 2.3.1.9 I Belongs to the thiolase family
IOOILHMJ_01066 5.4e-267 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IOOILHMJ_01067 6.5e-91 bioY S BioY family
IOOILHMJ_01068 1.8e-181 hemAT NT chemotaxis protein
IOOILHMJ_01069 2e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
IOOILHMJ_01070 1.4e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_01071 1.3e-32 yhzC S IDEAL
IOOILHMJ_01072 2.7e-108 comK K Competence transcription factor
IOOILHMJ_01073 2.3e-167 IQ Enoyl-(Acyl carrier protein) reductase
IOOILHMJ_01074 8.1e-39 yhjA S Excalibur calcium-binding domain
IOOILHMJ_01075 2.2e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOOILHMJ_01076 6.9e-27 yhjC S Protein of unknown function (DUF3311)
IOOILHMJ_01077 2.8e-58 yhjD
IOOILHMJ_01078 9.1e-110 yhjE S SNARE associated Golgi protein
IOOILHMJ_01079 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
IOOILHMJ_01080 4.8e-282 yhjG CH FAD binding domain
IOOILHMJ_01081 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
IOOILHMJ_01082 1.1e-212 glcP G Major Facilitator Superfamily
IOOILHMJ_01083 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
IOOILHMJ_01084 1.3e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
IOOILHMJ_01085 2e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
IOOILHMJ_01086 2.2e-187 yhjM 5.1.1.1 K Transcriptional regulator
IOOILHMJ_01088 4.2e-201 abrB S membrane
IOOILHMJ_01089 4.6e-211 EGP Transmembrane secretion effector
IOOILHMJ_01090 0.0 S Sugar transport-related sRNA regulator N-term
IOOILHMJ_01091 2.4e-77 yhjR S Rubrerythrin
IOOILHMJ_01092 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
IOOILHMJ_01093 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IOOILHMJ_01094 3.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IOOILHMJ_01095 0.0 sbcC L COG0419 ATPase involved in DNA repair
IOOILHMJ_01096 1.5e-49 yisB V COG1403 Restriction endonuclease
IOOILHMJ_01097 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
IOOILHMJ_01098 5.7e-65 gerPE S Spore germination protein GerPE
IOOILHMJ_01099 1.1e-23 gerPD S Spore germination protein
IOOILHMJ_01100 5.3e-54 gerPC S Spore germination protein
IOOILHMJ_01101 1.6e-30 gerPB S cell differentiation
IOOILHMJ_01102 1.9e-33 gerPA S Spore germination protein
IOOILHMJ_01103 1.5e-22 yisI S Spo0E like sporulation regulatory protein
IOOILHMJ_01104 3.5e-174 cotH M Spore Coat
IOOILHMJ_01105 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IOOILHMJ_01106 3.9e-57 yisL S UPF0344 protein
IOOILHMJ_01107 0.0 wprA O Belongs to the peptidase S8 family
IOOILHMJ_01108 1.3e-102 yisN S Protein of unknown function (DUF2777)
IOOILHMJ_01109 0.0 asnO 6.3.5.4 E Asparagine synthase
IOOILHMJ_01110 4e-118 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
IOOILHMJ_01111 1.5e-242 yisQ V Mate efflux family protein
IOOILHMJ_01112 1.6e-160 yisR K Transcriptional regulator
IOOILHMJ_01113 4.5e-183 purR K helix_turn _helix lactose operon repressor
IOOILHMJ_01114 2e-191 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
IOOILHMJ_01115 4.5e-91 yisT S DinB family
IOOILHMJ_01116 6e-106 argO S Lysine exporter protein LysE YggA
IOOILHMJ_01117 3.4e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOOILHMJ_01118 1.2e-35 mcbG S Pentapeptide repeats (9 copies)
IOOILHMJ_01119 4.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOOILHMJ_01120 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
IOOILHMJ_01121 3e-231 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IOOILHMJ_01122 1.1e-138 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IOOILHMJ_01123 2.6e-118 comB 3.1.3.71 H Belongs to the ComB family
IOOILHMJ_01124 5.4e-141 yitD 4.4.1.19 S synthase
IOOILHMJ_01125 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOOILHMJ_01126 2.3e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IOOILHMJ_01127 1.5e-228 yitG EGP Major facilitator Superfamily
IOOILHMJ_01128 4.8e-154 yitH K Acetyltransferase (GNAT) domain
IOOILHMJ_01129 1e-70 yjcF S Acetyltransferase (GNAT) domain
IOOILHMJ_01130 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IOOILHMJ_01131 3.1e-41 yajQ S Belongs to the UPF0234 family
IOOILHMJ_01132 6.9e-161 cvfB S protein conserved in bacteria
IOOILHMJ_01133 2.5e-93
IOOILHMJ_01134 2.8e-171
IOOILHMJ_01135 7.6e-97 S Sporulation delaying protein SdpA
IOOILHMJ_01136 1.5e-58 K Transcriptional regulator PadR-like family
IOOILHMJ_01137 1.5e-93
IOOILHMJ_01138 1.4e-44 yitR S Domain of unknown function (DUF3784)
IOOILHMJ_01139 7.9e-307 nprB 3.4.24.28 E Peptidase M4
IOOILHMJ_01140 9.3e-158 yitS S protein conserved in bacteria
IOOILHMJ_01141 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
IOOILHMJ_01142 1.9e-72 ipi S Intracellular proteinase inhibitor
IOOILHMJ_01143 1.2e-17 S Protein of unknown function (DUF3813)
IOOILHMJ_01145 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IOOILHMJ_01146 3.8e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IOOILHMJ_01147 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
IOOILHMJ_01148 1.5e-22 pilT S Proteolipid membrane potential modulator
IOOILHMJ_01149 6.4e-268 yitY C D-arabinono-1,4-lactone oxidase
IOOILHMJ_01150 6.5e-88 norB G Major Facilitator Superfamily
IOOILHMJ_01151 1.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOOILHMJ_01152 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOOILHMJ_01153 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IOOILHMJ_01154 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IOOILHMJ_01155 5.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOOILHMJ_01156 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
IOOILHMJ_01157 2.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOOILHMJ_01158 9.5e-28 yjzC S YjzC-like protein
IOOILHMJ_01159 2.3e-16 yjzD S Protein of unknown function (DUF2929)
IOOILHMJ_01160 1.5e-140 yjaU I carboxylic ester hydrolase activity
IOOILHMJ_01161 4e-101 yjaV
IOOILHMJ_01162 2.5e-183 med S Transcriptional activator protein med
IOOILHMJ_01163 7.3e-26 comZ S ComZ
IOOILHMJ_01164 5e-21 yjzB
IOOILHMJ_01165 6.6e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOOILHMJ_01166 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOOILHMJ_01167 9.5e-149 yjaZ O Zn-dependent protease
IOOILHMJ_01168 5.1e-184 appD P Belongs to the ABC transporter superfamily
IOOILHMJ_01169 9.4e-186 appF E Belongs to the ABC transporter superfamily
IOOILHMJ_01170 1.4e-282 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
IOOILHMJ_01171 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOOILHMJ_01172 1.4e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOOILHMJ_01173 5e-147 yjbA S Belongs to the UPF0736 family
IOOILHMJ_01174 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IOOILHMJ_01175 0.0 oppA E ABC transporter substrate-binding protein
IOOILHMJ_01176 2.2e-117 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOOILHMJ_01177 2.6e-183 oppD P Belongs to the ABC transporter superfamily
IOOILHMJ_01178 5.5e-172 oppF E Belongs to the ABC transporter superfamily
IOOILHMJ_01179 2.8e-205 yjbB EGP Major Facilitator Superfamily
IOOILHMJ_01180 2.4e-101 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOOILHMJ_01181 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOOILHMJ_01182 1.3e-111 yjbE P Integral membrane protein TerC family
IOOILHMJ_01183 8.9e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IOOILHMJ_01184 7e-217 yjbF S Competence protein
IOOILHMJ_01185 0.0 pepF E oligoendopeptidase F
IOOILHMJ_01186 1.8e-20
IOOILHMJ_01187 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IOOILHMJ_01188 1.4e-71 yjbI S Bacterial-like globin
IOOILHMJ_01189 2.3e-88 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IOOILHMJ_01190 1.6e-100 yjbK S protein conserved in bacteria
IOOILHMJ_01191 7.1e-62 yjbL S Belongs to the UPF0738 family
IOOILHMJ_01192 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
IOOILHMJ_01193 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOOILHMJ_01194 2.6e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOOILHMJ_01195 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IOOILHMJ_01196 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOOILHMJ_01197 2.7e-134 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOOILHMJ_01198 3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
IOOILHMJ_01199 2.6e-216 thiO 1.4.3.19 E Glycine oxidase
IOOILHMJ_01200 6.7e-30 thiS H thiamine diphosphate biosynthetic process
IOOILHMJ_01201 4.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IOOILHMJ_01202 2.1e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IOOILHMJ_01203 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOOILHMJ_01204 4.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IOOILHMJ_01205 3.2e-52 yjbX S Spore coat protein
IOOILHMJ_01206 3.4e-82 cotZ S Spore coat protein
IOOILHMJ_01207 3.4e-96 cotY S Spore coat protein Z
IOOILHMJ_01208 4e-71 cotX S Spore Coat Protein X and V domain
IOOILHMJ_01209 6.4e-22 cotW
IOOILHMJ_01210 1.4e-52 cotV S Spore Coat Protein X and V domain
IOOILHMJ_01211 1.9e-56 yjcA S Protein of unknown function (DUF1360)
IOOILHMJ_01214 4.9e-38 spoVIF S Stage VI sporulation protein F
IOOILHMJ_01215 0.0 yjcD 3.6.4.12 L DNA helicase
IOOILHMJ_01216 1.7e-38
IOOILHMJ_01217 1.5e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOOILHMJ_01218 4.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
IOOILHMJ_01219 7.7e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
IOOILHMJ_01220 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IOOILHMJ_01221 2.1e-216 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IOOILHMJ_01222 5.4e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
IOOILHMJ_01223 4.1e-212 yjcL S Protein of unknown function (DUF819)
IOOILHMJ_01225 3.1e-18
IOOILHMJ_01226 1.4e-39
IOOILHMJ_01227 1e-29
IOOILHMJ_01228 5.8e-18
IOOILHMJ_01232 1.3e-69 S response regulator aspartate phosphatase
IOOILHMJ_01233 5.4e-46 yjcS S Antibiotic biosynthesis monooxygenase
IOOILHMJ_01234 1.8e-42 yjcN
IOOILHMJ_01235 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
IOOILHMJ_01236 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
IOOILHMJ_01237 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
IOOILHMJ_01238 3.5e-49 yjdF S Protein of unknown function (DUF2992)
IOOILHMJ_01239 6.5e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
IOOILHMJ_01241 7.5e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOOILHMJ_01242 4.2e-29 S Domain of unknown function (DUF4177)
IOOILHMJ_01243 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
IOOILHMJ_01244 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IOOILHMJ_01246 2.7e-263 xynD 3.5.1.104 G Polysaccharide deacetylase
IOOILHMJ_01247 2.5e-80 S Protein of unknown function (DUF2690)
IOOILHMJ_01248 2.3e-20 yjfB S Putative motility protein
IOOILHMJ_01249 8.3e-165 yjfC O Predicted Zn-dependent protease (DUF2268)
IOOILHMJ_01250 1.2e-45 T PhoQ Sensor
IOOILHMJ_01251 2.9e-102 yjgB S Domain of unknown function (DUF4309)
IOOILHMJ_01252 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
IOOILHMJ_01253 4.3e-95 yjgD S Protein of unknown function (DUF1641)
IOOILHMJ_01254 1.2e-10 S Domain of unknown function (DUF4352)
IOOILHMJ_01255 5.9e-100 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
IOOILHMJ_01257 1.4e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
IOOILHMJ_01258 4.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IOOILHMJ_01259 8.2e-30
IOOILHMJ_01260 2.1e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IOOILHMJ_01261 1.3e-106 ybbM S transport system, permease component
IOOILHMJ_01262 9.2e-133 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
IOOILHMJ_01263 5.6e-175 yjlA EG Putative multidrug resistance efflux transporter
IOOILHMJ_01264 4e-92 yjlB S Cupin domain
IOOILHMJ_01265 7.1e-66 yjlC S Protein of unknown function (DUF1641)
IOOILHMJ_01266 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
IOOILHMJ_01267 1.8e-278 uxaC 5.3.1.12 G glucuronate isomerase
IOOILHMJ_01268 1.9e-248 yjmB G symporter YjmB
IOOILHMJ_01269 1.4e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IOOILHMJ_01270 1.4e-187 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
IOOILHMJ_01271 3.4e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IOOILHMJ_01272 9.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_01273 3.7e-227 exuT G Sugar (and other) transporter
IOOILHMJ_01274 6.8e-184 exuR K transcriptional
IOOILHMJ_01275 9.2e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
IOOILHMJ_01276 1.6e-282 uxaA 4.2.1.7, 4.4.1.24 G Altronate
IOOILHMJ_01277 7.4e-130 MA20_18170 S membrane transporter protein
IOOILHMJ_01278 1.1e-78 yjoA S DinB family
IOOILHMJ_01279 3.6e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
IOOILHMJ_01280 1.8e-212 S response regulator aspartate phosphatase
IOOILHMJ_01282 6.3e-41 S YCII-related domain
IOOILHMJ_01283 1.5e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
IOOILHMJ_01284 4.4e-59 yjqA S Bacterial PH domain
IOOILHMJ_01285 1.8e-110 yjqB S Pfam:DUF867
IOOILHMJ_01286 4.4e-160 ydbD P Catalase
IOOILHMJ_01287 1.1e-109 xkdA E IrrE N-terminal-like domain
IOOILHMJ_01288 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
IOOILHMJ_01290 2.1e-154 xkdB K sequence-specific DNA binding
IOOILHMJ_01291 5.4e-118 xkdC L Bacterial dnaA protein
IOOILHMJ_01294 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
IOOILHMJ_01295 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IOOILHMJ_01296 1.4e-139 xtmA L phage terminase small subunit
IOOILHMJ_01297 1.5e-252 xtmB S phage terminase, large subunit
IOOILHMJ_01298 1.5e-283 yqbA S portal protein
IOOILHMJ_01299 7.7e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
IOOILHMJ_01300 5.8e-169 xkdG S Phage capsid family
IOOILHMJ_01301 1.5e-62 yqbG S Protein of unknown function (DUF3199)
IOOILHMJ_01302 1.9e-64 yqbH S Domain of unknown function (DUF3599)
IOOILHMJ_01303 3.8e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
IOOILHMJ_01304 1.6e-76 xkdJ
IOOILHMJ_01305 3.2e-256 xkdK S Phage tail sheath C-terminal domain
IOOILHMJ_01306 6.1e-76 xkdM S Phage tail tube protein
IOOILHMJ_01307 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
IOOILHMJ_01308 0.0 xkdO L Transglycosylase SLT domain
IOOILHMJ_01309 7.8e-120 xkdP S Lysin motif
IOOILHMJ_01310 3.1e-181 yqbQ 3.2.1.96 G NLP P60 protein
IOOILHMJ_01311 1e-38 xkdR S Protein of unknown function (DUF2577)
IOOILHMJ_01312 2.4e-69 xkdS S Protein of unknown function (DUF2634)
IOOILHMJ_01313 3.3e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IOOILHMJ_01314 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
IOOILHMJ_01315 1.3e-39
IOOILHMJ_01316 0.0
IOOILHMJ_01317 5.5e-42 xkdW S XkdW protein
IOOILHMJ_01318 5.5e-22 xkdX
IOOILHMJ_01319 2.9e-151 xepA
IOOILHMJ_01320 6.2e-39 xhlA S Haemolysin XhlA
IOOILHMJ_01321 2.7e-39 xhlB S SPP1 phage holin
IOOILHMJ_01322 1.1e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IOOILHMJ_01324 6.7e-23 spoIISB S Stage II sporulation protein SB
IOOILHMJ_01325 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
IOOILHMJ_01326 5.8e-175 pit P phosphate transporter
IOOILHMJ_01327 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
IOOILHMJ_01328 4e-240 steT E amino acid
IOOILHMJ_01329 2.3e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
IOOILHMJ_01330 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOOILHMJ_01331 7.1e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IOOILHMJ_01333 1.6e-204 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOOILHMJ_01334 1.2e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
IOOILHMJ_01335 5.1e-153 dppA E D-aminopeptidase
IOOILHMJ_01336 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOOILHMJ_01337 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOOILHMJ_01338 4.8e-185 dppD P Belongs to the ABC transporter superfamily
IOOILHMJ_01339 0.0 dppE E ABC transporter substrate-binding protein
IOOILHMJ_01341 6.4e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IOOILHMJ_01342 8.3e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IOOILHMJ_01343 4.5e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IOOILHMJ_01344 2.9e-187 ykfD E Belongs to the ABC transporter superfamily
IOOILHMJ_01345 1.8e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
IOOILHMJ_01346 2.5e-158 ykgA E Amidinotransferase
IOOILHMJ_01347 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
IOOILHMJ_01348 6.8e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IOOILHMJ_01349 7.2e-09
IOOILHMJ_01350 1.5e-127 ykjA S Protein of unknown function (DUF421)
IOOILHMJ_01351 3.7e-96 ykkA S Protein of unknown function (DUF664)
IOOILHMJ_01352 5.6e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOOILHMJ_01353 1.3e-54 ykkC P Multidrug resistance protein
IOOILHMJ_01354 9.1e-50 ykkD P Multidrug resistance protein
IOOILHMJ_01355 4.3e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IOOILHMJ_01356 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOOILHMJ_01357 3.4e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOOILHMJ_01358 1.3e-70 ohrA O Organic hydroperoxide resistance protein
IOOILHMJ_01359 4.4e-74 ohrR K COG1846 Transcriptional regulators
IOOILHMJ_01360 1.4e-71 ohrB O Organic hydroperoxide resistance protein
IOOILHMJ_01361 9e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
IOOILHMJ_01362 1.8e-97 5.4.2.11 G Belongs to the phosphoglycerate mutase family
IOOILHMJ_01363 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOOILHMJ_01364 5e-176 isp O Belongs to the peptidase S8 family
IOOILHMJ_01365 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOOILHMJ_01366 1.5e-135 ykoC P Cobalt transport protein
IOOILHMJ_01367 6.8e-306 P ABC transporter, ATP-binding protein
IOOILHMJ_01368 2.9e-89 ykoE S ABC-type cobalt transport system, permease component
IOOILHMJ_01369 1.5e-109 ykoF S YKOF-related Family
IOOILHMJ_01370 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_01371 5.7e-242 ykoH 2.7.13.3 T Histidine kinase
IOOILHMJ_01372 9.5e-113 ykoI S Peptidase propeptide and YPEB domain
IOOILHMJ_01373 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
IOOILHMJ_01376 1.1e-221 mgtE P Acts as a magnesium transporter
IOOILHMJ_01377 1.4e-53 tnrA K transcriptional
IOOILHMJ_01378 5.9e-18
IOOILHMJ_01379 6.9e-26 ykoL
IOOILHMJ_01380 1.3e-81 mhqR K transcriptional
IOOILHMJ_01381 1.7e-212 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IOOILHMJ_01382 1.3e-96 ykoP G polysaccharide deacetylase
IOOILHMJ_01383 1e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
IOOILHMJ_01384 0.0 ykoS
IOOILHMJ_01385 1.8e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IOOILHMJ_01386 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
IOOILHMJ_01387 1.1e-158 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IOOILHMJ_01388 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
IOOILHMJ_01389 1.1e-107 ykoX S membrane-associated protein
IOOILHMJ_01390 1.8e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IOOILHMJ_01391 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOOILHMJ_01392 4.7e-104 rsgI S Anti-sigma factor N-terminus
IOOILHMJ_01393 1.9e-26 sspD S small acid-soluble spore protein
IOOILHMJ_01394 6.1e-123 ykrK S Domain of unknown function (DUF1836)
IOOILHMJ_01395 3.5e-155 htpX O Belongs to the peptidase M48B family
IOOILHMJ_01396 2.8e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
IOOILHMJ_01397 1.2e-10 ydfR S Protein of unknown function (DUF421)
IOOILHMJ_01398 4.5e-22 ykzE
IOOILHMJ_01399 2.5e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
IOOILHMJ_01400 0.0 kinE 2.7.13.3 T Histidine kinase
IOOILHMJ_01401 3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOOILHMJ_01403 6.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IOOILHMJ_01404 2.2e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IOOILHMJ_01405 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IOOILHMJ_01406 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
IOOILHMJ_01407 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IOOILHMJ_01408 2.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IOOILHMJ_01409 4.7e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IOOILHMJ_01410 3.2e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IOOILHMJ_01411 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
IOOILHMJ_01412 6.4e-09 S Spo0E like sporulation regulatory protein
IOOILHMJ_01413 3.2e-61 eag
IOOILHMJ_01414 1.8e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
IOOILHMJ_01415 2.3e-75 ykvE K transcriptional
IOOILHMJ_01416 2.5e-125 motB N Flagellar motor protein
IOOILHMJ_01417 1e-137 motA N flagellar motor
IOOILHMJ_01418 0.0 clpE O Belongs to the ClpA ClpB family
IOOILHMJ_01419 3.3e-181 ykvI S membrane
IOOILHMJ_01420 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IOOILHMJ_01421 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
IOOILHMJ_01422 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IOOILHMJ_01423 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IOOILHMJ_01424 6e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
IOOILHMJ_01425 3e-34 3.5.1.104 M LysM domain
IOOILHMJ_01426 6.4e-160 G Glycosyl hydrolases family 18
IOOILHMJ_01427 4.8e-45 ykvR S Protein of unknown function (DUF3219)
IOOILHMJ_01428 6e-25 ykvS S protein conserved in bacteria
IOOILHMJ_01429 6.7e-27
IOOILHMJ_01430 6.3e-72 ykvT 3.5.1.28 M Cell Wall Hydrolase
IOOILHMJ_01431 4.2e-237 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOOILHMJ_01432 1.4e-89 stoA CO thiol-disulfide
IOOILHMJ_01433 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IOOILHMJ_01434 2.3e-09
IOOILHMJ_01435 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IOOILHMJ_01437 8.3e-179 ykvZ 5.1.1.1 K Transcriptional regulator
IOOILHMJ_01439 1.7e-127 glcT K antiterminator
IOOILHMJ_01440 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOOILHMJ_01441 2.1e-39 ptsH G phosphocarrier protein HPr
IOOILHMJ_01442 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOOILHMJ_01443 7.2e-39 splA S Transcriptional regulator
IOOILHMJ_01444 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
IOOILHMJ_01445 1.9e-124 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOOILHMJ_01446 1.2e-256 mcpC NT chemotaxis protein
IOOILHMJ_01447 5.6e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IOOILHMJ_01448 2.3e-123 ykwD J protein with SCP PR1 domains
IOOILHMJ_01449 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
IOOILHMJ_01450 0.0 pilS 2.7.13.3 T Histidine kinase
IOOILHMJ_01451 1.8e-220 patA 2.6.1.1 E Aminotransferase
IOOILHMJ_01452 2.2e-15
IOOILHMJ_01453 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
IOOILHMJ_01454 1.7e-84 ykyB S YkyB-like protein
IOOILHMJ_01455 2.8e-238 ykuC EGP Major facilitator Superfamily
IOOILHMJ_01456 3.9e-87 ykuD S protein conserved in bacteria
IOOILHMJ_01457 2.7e-165 ykuE S Metallophosphoesterase
IOOILHMJ_01458 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_01459 3.7e-232 ykuI T Diguanylate phosphodiesterase
IOOILHMJ_01461 3.9e-37 ykuJ S protein conserved in bacteria
IOOILHMJ_01462 1.3e-93 ykuK S Ribonuclease H-like
IOOILHMJ_01463 3.9e-27 ykzF S Antirepressor AbbA
IOOILHMJ_01464 1.6e-76 ykuL S CBS domain
IOOILHMJ_01465 3.5e-168 ccpC K Transcriptional regulator
IOOILHMJ_01466 4.3e-83 fld C Flavodoxin domain
IOOILHMJ_01467 4.4e-174 ykuO
IOOILHMJ_01468 8.7e-78 fld C Flavodoxin
IOOILHMJ_01469 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOOILHMJ_01470 7.9e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOOILHMJ_01471 9e-37 ykuS S Belongs to the UPF0180 family
IOOILHMJ_01472 5.7e-141 ykuT M Mechanosensitive ion channel
IOOILHMJ_01473 3.9e-101 ykuU O Alkyl hydroperoxide reductase
IOOILHMJ_01474 1.6e-79 ykuV CO thiol-disulfide
IOOILHMJ_01475 5.8e-95 rok K Repressor of ComK
IOOILHMJ_01476 1.4e-141 yknT
IOOILHMJ_01477 2.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IOOILHMJ_01478 1.7e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IOOILHMJ_01479 2.6e-244 moeA 2.10.1.1 H molybdopterin
IOOILHMJ_01480 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IOOILHMJ_01481 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
IOOILHMJ_01482 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IOOILHMJ_01483 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
IOOILHMJ_01484 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
IOOILHMJ_01485 2.9e-117 yknW S Yip1 domain
IOOILHMJ_01486 4.7e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOOILHMJ_01487 2.5e-124 macB V ABC transporter, ATP-binding protein
IOOILHMJ_01488 8.9e-207 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
IOOILHMJ_01489 3.1e-136 fruR K Transcriptional regulator
IOOILHMJ_01490 4e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
IOOILHMJ_01491 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IOOILHMJ_01492 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IOOILHMJ_01493 8.1e-39 ykoA
IOOILHMJ_01494 3.8e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOOILHMJ_01495 2.2e-57 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOOILHMJ_01496 6.5e-99 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOOILHMJ_01497 1e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IOOILHMJ_01498 1.1e-12 S Uncharacterized protein YkpC
IOOILHMJ_01499 7.7e-183 mreB D Rod-share determining protein MreBH
IOOILHMJ_01500 1.5e-43 abrB K of stationary sporulation gene expression
IOOILHMJ_01501 1.3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
IOOILHMJ_01502 1.1e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
IOOILHMJ_01503 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
IOOILHMJ_01504 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IOOILHMJ_01505 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOOILHMJ_01506 8.2e-31 ykzG S Belongs to the UPF0356 family
IOOILHMJ_01507 1.3e-145 ykrA S hydrolases of the HAD superfamily
IOOILHMJ_01508 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOOILHMJ_01510 3e-108 recN L Putative cell-wall binding lipoprotein
IOOILHMJ_01511 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOOILHMJ_01512 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOOILHMJ_01513 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOOILHMJ_01514 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOOILHMJ_01515 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
IOOILHMJ_01516 1.2e-10 S SR1 protein
IOOILHMJ_01517 1e-276 speA 4.1.1.19 E Arginine
IOOILHMJ_01518 1.6e-42 yktA S Belongs to the UPF0223 family
IOOILHMJ_01519 2.1e-117 yktB S Belongs to the UPF0637 family
IOOILHMJ_01520 7.1e-26 ykzI
IOOILHMJ_01521 1.1e-149 suhB 3.1.3.25 G Inositol monophosphatase
IOOILHMJ_01522 6.4e-76 ykzC S Acetyltransferase (GNAT) family
IOOILHMJ_01523 5.1e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IOOILHMJ_01524 1.8e-292 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
IOOILHMJ_01525 0.0 ylaA
IOOILHMJ_01526 2.7e-42 ylaB
IOOILHMJ_01527 1.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_01528 1.2e-11 sigC S Putative zinc-finger
IOOILHMJ_01529 2.6e-37 ylaE
IOOILHMJ_01530 2e-20 S Family of unknown function (DUF5325)
IOOILHMJ_01531 0.0 typA T GTP-binding protein TypA
IOOILHMJ_01532 4.2e-47 ylaH S YlaH-like protein
IOOILHMJ_01533 2.5e-32 ylaI S protein conserved in bacteria
IOOILHMJ_01534 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOOILHMJ_01535 6.8e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
IOOILHMJ_01536 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IOOILHMJ_01537 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
IOOILHMJ_01538 8.7e-44 ylaN S Belongs to the UPF0358 family
IOOILHMJ_01539 1.4e-212 ftsW D Belongs to the SEDS family
IOOILHMJ_01540 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IOOILHMJ_01541 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IOOILHMJ_01542 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IOOILHMJ_01543 3.1e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IOOILHMJ_01544 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IOOILHMJ_01545 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IOOILHMJ_01546 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IOOILHMJ_01547 6.8e-167 ctaG S cytochrome c oxidase
IOOILHMJ_01548 2.6e-61 ylbA S YugN-like family
IOOILHMJ_01549 2.6e-74 ylbB T COG0517 FOG CBS domain
IOOILHMJ_01550 9.6e-200 ylbC S protein with SCP PR1 domains
IOOILHMJ_01551 4.1e-63 ylbD S Putative coat protein
IOOILHMJ_01552 6.7e-37 ylbE S YlbE-like protein
IOOILHMJ_01553 1.8e-75 ylbF S Belongs to the UPF0342 family
IOOILHMJ_01554 7.5e-39 ylbG S UPF0298 protein
IOOILHMJ_01555 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
IOOILHMJ_01556 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOOILHMJ_01557 7.2e-220 ylbJ S Sporulation integral membrane protein YlbJ
IOOILHMJ_01558 2.9e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
IOOILHMJ_01559 9.7e-186 ylbL T Belongs to the peptidase S16 family
IOOILHMJ_01560 9.8e-14 yqgA
IOOILHMJ_01561 4.8e-123 ylbM S Belongs to the UPF0348 family
IOOILHMJ_01563 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
IOOILHMJ_01564 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IOOILHMJ_01565 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IOOILHMJ_01566 1.5e-88 ylbP K n-acetyltransferase
IOOILHMJ_01567 5.7e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOOILHMJ_01568 2.5e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IOOILHMJ_01569 2.9e-78 mraZ K Belongs to the MraZ family
IOOILHMJ_01570 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOOILHMJ_01571 3.7e-44 ftsL D Essential cell division protein
IOOILHMJ_01572 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IOOILHMJ_01573 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
IOOILHMJ_01574 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOOILHMJ_01575 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOOILHMJ_01576 4.5e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOOILHMJ_01577 5.7e-186 spoVE D Belongs to the SEDS family
IOOILHMJ_01578 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOOILHMJ_01579 9e-167 murB 1.3.1.98 M cell wall formation
IOOILHMJ_01580 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOOILHMJ_01581 2.4e-103 ylxW S protein conserved in bacteria
IOOILHMJ_01582 1e-102 ylxX S protein conserved in bacteria
IOOILHMJ_01583 3.3e-56 sbp S small basic protein
IOOILHMJ_01584 4.6e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOOILHMJ_01585 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOOILHMJ_01586 0.0 bpr O COG1404 Subtilisin-like serine proteases
IOOILHMJ_01588 8e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IOOILHMJ_01589 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOOILHMJ_01590 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOOILHMJ_01591 9e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IOOILHMJ_01592 2.2e-251 argE 3.5.1.16 E Acetylornithine deacetylase
IOOILHMJ_01593 2.4e-37 ylmC S sporulation protein
IOOILHMJ_01594 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
IOOILHMJ_01595 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOOILHMJ_01596 6.7e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOOILHMJ_01597 1.3e-39 yggT S membrane
IOOILHMJ_01598 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
IOOILHMJ_01599 2.6e-67 divIVA D Cell division initiation protein
IOOILHMJ_01600 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOOILHMJ_01601 1.9e-62 dksA T COG1734 DnaK suppressor protein
IOOILHMJ_01602 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOOILHMJ_01603 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOOILHMJ_01604 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOOILHMJ_01605 1.5e-231 pyrP F Xanthine uracil
IOOILHMJ_01606 4.1e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IOOILHMJ_01607 1.4e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOOILHMJ_01608 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOOILHMJ_01609 0.0 carB 6.3.5.5 F Belongs to the CarB family
IOOILHMJ_01610 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IOOILHMJ_01611 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOOILHMJ_01612 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOOILHMJ_01613 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOOILHMJ_01615 1.1e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IOOILHMJ_01616 1.2e-178 cysP P phosphate transporter
IOOILHMJ_01617 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IOOILHMJ_01618 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
IOOILHMJ_01619 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IOOILHMJ_01620 9.2e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
IOOILHMJ_01621 4.8e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
IOOILHMJ_01622 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IOOILHMJ_01623 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
IOOILHMJ_01624 2.4e-156 yloC S stress-induced protein
IOOILHMJ_01625 1.5e-40 ylzA S Belongs to the UPF0296 family
IOOILHMJ_01626 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IOOILHMJ_01627 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOOILHMJ_01628 1.7e-221 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOOILHMJ_01629 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOOILHMJ_01630 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOOILHMJ_01631 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOOILHMJ_01632 2.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOOILHMJ_01633 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IOOILHMJ_01634 1.3e-139 stp 3.1.3.16 T phosphatase
IOOILHMJ_01635 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IOOILHMJ_01636 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOOILHMJ_01637 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IOOILHMJ_01638 2e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
IOOILHMJ_01639 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IOOILHMJ_01640 5.5e-59 asp S protein conserved in bacteria
IOOILHMJ_01641 6.6e-301 yloV S kinase related to dihydroxyacetone kinase
IOOILHMJ_01642 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
IOOILHMJ_01643 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
IOOILHMJ_01644 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOOILHMJ_01645 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IOOILHMJ_01646 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOOILHMJ_01647 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IOOILHMJ_01648 5.1e-128 IQ reductase
IOOILHMJ_01649 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOOILHMJ_01650 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOOILHMJ_01651 0.0 smc D Required for chromosome condensation and partitioning
IOOILHMJ_01652 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOOILHMJ_01653 2.9e-87
IOOILHMJ_01654 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOOILHMJ_01655 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOOILHMJ_01656 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IOOILHMJ_01657 4.5e-36 ylqC S Belongs to the UPF0109 family
IOOILHMJ_01658 1.4e-60 ylqD S YlqD protein
IOOILHMJ_01659 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOOILHMJ_01660 2.7e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IOOILHMJ_01661 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOOILHMJ_01662 1.8e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOOILHMJ_01663 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOOILHMJ_01664 2.3e-288 ylqG
IOOILHMJ_01665 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
IOOILHMJ_01666 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IOOILHMJ_01667 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IOOILHMJ_01668 1.3e-134 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
IOOILHMJ_01669 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOOILHMJ_01670 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOOILHMJ_01671 5.7e-169 xerC L tyrosine recombinase XerC
IOOILHMJ_01672 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOOILHMJ_01673 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOOILHMJ_01674 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IOOILHMJ_01675 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IOOILHMJ_01676 2e-74 flgC N Belongs to the flagella basal body rod proteins family
IOOILHMJ_01677 1.9e-31 fliE N Flagellar hook-basal body
IOOILHMJ_01678 1e-253 fliF N The M ring may be actively involved in energy transduction
IOOILHMJ_01679 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IOOILHMJ_01680 2.8e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
IOOILHMJ_01681 1.7e-238 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IOOILHMJ_01682 1.5e-69 fliJ N Flagellar biosynthesis chaperone
IOOILHMJ_01683 3.8e-36 ylxF S MgtE intracellular N domain
IOOILHMJ_01684 4e-217 fliK N Flagellar hook-length control protein
IOOILHMJ_01685 1.1e-71 flgD N Flagellar basal body rod modification protein
IOOILHMJ_01686 1.3e-137 flgG N Flagellar basal body rod
IOOILHMJ_01687 1.8e-48 fliL N Controls the rotational direction of flagella during chemotaxis
IOOILHMJ_01688 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IOOILHMJ_01689 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IOOILHMJ_01690 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
IOOILHMJ_01691 1.3e-95 fliZ N Flagellar biosynthesis protein, FliO
IOOILHMJ_01692 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
IOOILHMJ_01693 2.2e-36 fliQ N Role in flagellar biosynthesis
IOOILHMJ_01694 1.8e-131 fliR N Flagellar biosynthetic protein FliR
IOOILHMJ_01695 1.8e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IOOILHMJ_01696 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IOOILHMJ_01697 1.5e-200 flhF N Flagellar biosynthesis regulator FlhF
IOOILHMJ_01698 9.8e-158 flhG D Belongs to the ParA family
IOOILHMJ_01699 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IOOILHMJ_01700 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
IOOILHMJ_01701 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
IOOILHMJ_01702 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IOOILHMJ_01703 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IOOILHMJ_01704 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOOILHMJ_01705 2.4e-76 ylxL
IOOILHMJ_01706 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
IOOILHMJ_01707 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOOILHMJ_01708 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IOOILHMJ_01709 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOOILHMJ_01710 1.9e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOOILHMJ_01711 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IOOILHMJ_01712 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IOOILHMJ_01713 3.8e-232 rasP M zinc metalloprotease
IOOILHMJ_01714 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOOILHMJ_01715 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOOILHMJ_01716 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
IOOILHMJ_01717 1.1e-203 nusA K Participates in both transcription termination and antitermination
IOOILHMJ_01718 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
IOOILHMJ_01719 3.1e-47 ylxQ J ribosomal protein
IOOILHMJ_01720 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOOILHMJ_01721 3.9e-44 ylxP S protein conserved in bacteria
IOOILHMJ_01722 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOOILHMJ_01723 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOOILHMJ_01724 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IOOILHMJ_01725 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOOILHMJ_01726 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IOOILHMJ_01727 9.4e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
IOOILHMJ_01728 4.4e-233 pepR S Belongs to the peptidase M16 family
IOOILHMJ_01729 2.6e-42 ymxH S YlmC YmxH family
IOOILHMJ_01730 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
IOOILHMJ_01731 3.7e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IOOILHMJ_01732 2.1e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOOILHMJ_01733 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IOOILHMJ_01734 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOOILHMJ_01735 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOOILHMJ_01736 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
IOOILHMJ_01737 4.4e-32 S YlzJ-like protein
IOOILHMJ_01738 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IOOILHMJ_01739 1.4e-133 ymfC K Transcriptional regulator
IOOILHMJ_01740 1.4e-204 ymfD EGP Major facilitator Superfamily
IOOILHMJ_01741 4.6e-233 ymfF S Peptidase M16
IOOILHMJ_01742 9.2e-242 ymfH S zinc protease
IOOILHMJ_01743 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IOOILHMJ_01744 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
IOOILHMJ_01745 2.7e-143 ymfK S Protein of unknown function (DUF3388)
IOOILHMJ_01746 1.9e-124 ymfM S protein conserved in bacteria
IOOILHMJ_01747 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOOILHMJ_01748 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
IOOILHMJ_01749 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOOILHMJ_01750 1.7e-210 pbpX V Beta-lactamase
IOOILHMJ_01751 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
IOOILHMJ_01752 1.9e-152 ymdB S protein conserved in bacteria
IOOILHMJ_01753 1.2e-36 spoVS S Stage V sporulation protein S
IOOILHMJ_01754 5.1e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IOOILHMJ_01755 1.1e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOOILHMJ_01756 8.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IOOILHMJ_01757 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IOOILHMJ_01758 2.2e-88 cotE S Spore coat protein
IOOILHMJ_01759 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOOILHMJ_01760 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOOILHMJ_01761 1.6e-66 S Regulatory protein YrvL
IOOILHMJ_01762 1e-96 ymcC S Membrane
IOOILHMJ_01763 7.6e-109 pksA K Transcriptional regulator
IOOILHMJ_01764 3.1e-124 pksB 3.1.2.6 S Polyketide biosynthesis
IOOILHMJ_01765 1.6e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IOOILHMJ_01767 4.5e-180 pksD Q Acyl transferase domain
IOOILHMJ_01768 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IOOILHMJ_01769 1.4e-37 acpK IQ Phosphopantetheine attachment site
IOOILHMJ_01770 3.9e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOOILHMJ_01771 3.9e-245 pksG 2.3.3.10 I synthase
IOOILHMJ_01772 2.7e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
IOOILHMJ_01773 2.3e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IOOILHMJ_01774 0.0 rhiB IQ polyketide synthase
IOOILHMJ_01775 0.0 pfaA Q Polyketide synthase of type I
IOOILHMJ_01776 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
IOOILHMJ_01777 0.0 dhbF IQ polyketide synthase
IOOILHMJ_01778 0.0 pks13 HQ Beta-ketoacyl synthase
IOOILHMJ_01779 6.9e-231 cypA C Cytochrome P450
IOOILHMJ_01780 2.6e-61 ymzB
IOOILHMJ_01781 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
IOOILHMJ_01782 4.3e-250 aprX O Belongs to the peptidase S8 family
IOOILHMJ_01783 1.9e-07 K Transcriptional regulator
IOOILHMJ_01784 2.1e-126 ymaC S Replication protein
IOOILHMJ_01785 3.5e-79 ymaD O redox protein, regulator of disulfide bond formation
IOOILHMJ_01786 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
IOOILHMJ_01787 5.4e-50 ebrA P Small Multidrug Resistance protein
IOOILHMJ_01789 2.1e-46 ymaF S YmaF family
IOOILHMJ_01790 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOOILHMJ_01791 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IOOILHMJ_01792 1.2e-21
IOOILHMJ_01793 6.4e-22 ymzA
IOOILHMJ_01794 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
IOOILHMJ_01795 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOOILHMJ_01796 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOOILHMJ_01797 1e-108 ymaB
IOOILHMJ_01798 2.2e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IOOILHMJ_01799 1.7e-176 spoVK O stage V sporulation protein K
IOOILHMJ_01800 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOOILHMJ_01801 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IOOILHMJ_01802 4.3e-68 glnR K transcriptional
IOOILHMJ_01803 7e-261 glnA 6.3.1.2 E glutamine synthetase
IOOILHMJ_01804 2.8e-24
IOOILHMJ_01805 7.1e-27
IOOILHMJ_01807 1.7e-54 M nuclease activity
IOOILHMJ_01808 3.4e-209 M nucleic acid phosphodiester bond hydrolysis
IOOILHMJ_01810 6.6e-10
IOOILHMJ_01811 4.2e-25
IOOILHMJ_01812 9.7e-128
IOOILHMJ_01813 3.5e-36
IOOILHMJ_01814 1.9e-92 G SMI1-KNR4 cell-wall
IOOILHMJ_01815 7.7e-94 ynaC
IOOILHMJ_01816 1.3e-96 ynaD J Acetyltransferase (GNAT) domain
IOOILHMJ_01817 3.6e-75 S CAAX protease self-immunity
IOOILHMJ_01818 9.4e-09 S Uncharacterised protein family (UPF0715)
IOOILHMJ_01819 1.5e-09 K Cro/C1-type HTH DNA-binding domain
IOOILHMJ_01820 3.1e-113 ynaE S Domain of unknown function (DUF3885)
IOOILHMJ_01823 3.9e-254 xynT G MFS/sugar transport protein
IOOILHMJ_01824 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
IOOILHMJ_01825 1.6e-213 xylR GK ROK family
IOOILHMJ_01826 2e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IOOILHMJ_01827 7.3e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
IOOILHMJ_01828 7.5e-112 yokF 3.1.31.1 L RNA catabolic process
IOOILHMJ_01829 6.1e-255 iolT EGP Major facilitator Superfamily
IOOILHMJ_01830 2.7e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOOILHMJ_01831 8.5e-81 yncE S Protein of unknown function (DUF2691)
IOOILHMJ_01832 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
IOOILHMJ_01835 1.1e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOOILHMJ_01836 1e-198 L COG3666 Transposase and inactivated derivatives
IOOILHMJ_01838 2.7e-126 S Domain of unknown function, YrpD
IOOILHMJ_01841 7.9e-25 tatA U protein secretion
IOOILHMJ_01842 1.5e-70
IOOILHMJ_01843 9.8e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
IOOILHMJ_01846 6.9e-284 gerAA EG Spore germination protein
IOOILHMJ_01847 7.2e-195 gerAB U Spore germination
IOOILHMJ_01848 2.7e-211 gerLC S Spore germination protein
IOOILHMJ_01849 6.8e-150 yndG S DoxX-like family
IOOILHMJ_01850 6e-114 yndH S Domain of unknown function (DUF4166)
IOOILHMJ_01851 1.5e-308 yndJ S YndJ-like protein
IOOILHMJ_01853 8.1e-137 yndL S Replication protein
IOOILHMJ_01854 1.7e-73 yndM S Protein of unknown function (DUF2512)
IOOILHMJ_01855 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IOOILHMJ_01856 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOOILHMJ_01857 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IOOILHMJ_01858 6.6e-111 yneB L resolvase
IOOILHMJ_01859 1.3e-32 ynzC S UPF0291 protein
IOOILHMJ_01860 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IOOILHMJ_01861 3.7e-81 yneE S Sporulation inhibitor of replication protein sirA
IOOILHMJ_01862 1.8e-28 yneF S UPF0154 protein
IOOILHMJ_01863 1.2e-126 ccdA O cytochrome c biogenesis protein
IOOILHMJ_01864 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
IOOILHMJ_01865 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
IOOILHMJ_01866 4.7e-73 yneK S Protein of unknown function (DUF2621)
IOOILHMJ_01867 1.7e-63 hspX O Spore coat protein
IOOILHMJ_01868 3.9e-19 sspP S Belongs to the SspP family
IOOILHMJ_01869 2.5e-14 sspO S Belongs to the SspO family
IOOILHMJ_01870 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IOOILHMJ_01871 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IOOILHMJ_01873 3.1e-08 sspN S Small acid-soluble spore protein N family
IOOILHMJ_01874 3.9e-35 tlp S Belongs to the Tlp family
IOOILHMJ_01875 1.6e-73 yneP S Thioesterase-like superfamily
IOOILHMJ_01876 4.9e-53 yneQ
IOOILHMJ_01877 4.1e-49 yneR S Belongs to the HesB IscA family
IOOILHMJ_01878 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOOILHMJ_01879 6.6e-69 yccU S CoA-binding protein
IOOILHMJ_01880 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOOILHMJ_01881 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOOILHMJ_01882 2.3e-12
IOOILHMJ_01883 1.3e-57 ynfC
IOOILHMJ_01884 9e-251 agcS E Sodium alanine symporter
IOOILHMJ_01885 3.2e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
IOOILHMJ_01887 6.3e-210 S Platelet-activating factor acetylhydrolase, isoform II
IOOILHMJ_01888 2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
IOOILHMJ_01889 1.2e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
IOOILHMJ_01890 5.4e-80 yngA S membrane
IOOILHMJ_01891 1.5e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOOILHMJ_01892 5.5e-104 yngC S membrane-associated protein
IOOILHMJ_01893 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
IOOILHMJ_01894 1e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOOILHMJ_01895 5.1e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IOOILHMJ_01896 2e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
IOOILHMJ_01897 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
IOOILHMJ_01898 4.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
IOOILHMJ_01899 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IOOILHMJ_01900 5.4e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
IOOILHMJ_01901 9.4e-28 S Family of unknown function (DUF5367)
IOOILHMJ_01902 9.1e-305 yngK T Glycosyl hydrolase-like 10
IOOILHMJ_01903 2e-62 yngL S Protein of unknown function (DUF1360)
IOOILHMJ_01904 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
IOOILHMJ_01905 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_01906 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_01907 8e-174 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_01908 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_01909 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_01910 3.5e-269 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
IOOILHMJ_01911 1.2e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
IOOILHMJ_01912 2.5e-245 yoeA V MATE efflux family protein
IOOILHMJ_01913 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
IOOILHMJ_01915 2.2e-96 L Integrase
IOOILHMJ_01916 1.9e-33 yoeD G Helix-turn-helix domain
IOOILHMJ_01917 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IOOILHMJ_01918 1.1e-153 gltR1 K Transcriptional regulator
IOOILHMJ_01919 1.2e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IOOILHMJ_01920 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IOOILHMJ_01921 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
IOOILHMJ_01922 7.8e-155 gltC K Transcriptional regulator
IOOILHMJ_01923 2.7e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOOILHMJ_01924 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOOILHMJ_01925 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IOOILHMJ_01926 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_01927 1.3e-37 yoxC S Bacterial protein of unknown function (DUF948)
IOOILHMJ_01928 3.2e-133 yoxB
IOOILHMJ_01929 1.2e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOOILHMJ_01930 8.9e-234 yoaB EGP Major facilitator Superfamily
IOOILHMJ_01931 7.2e-275 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
IOOILHMJ_01932 1.2e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOOILHMJ_01933 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOOILHMJ_01934 1.3e-34 yoaF
IOOILHMJ_01935 3.8e-12
IOOILHMJ_01936 8.5e-34 S Protein of unknown function (DUF4025)
IOOILHMJ_01937 1.8e-181 mcpU NT methyl-accepting chemotaxis protein
IOOILHMJ_01938 2.2e-276 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
IOOILHMJ_01939 1.1e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
IOOILHMJ_01940 6.8e-111 yoaK S Membrane
IOOILHMJ_01941 2.8e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
IOOILHMJ_01942 5.6e-55 yoqW S Belongs to the SOS response-associated peptidase family
IOOILHMJ_01944 1e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
IOOILHMJ_01947 4.4e-83
IOOILHMJ_01948 1e-170 yoaR V vancomycin resistance protein
IOOILHMJ_01949 1.8e-73 yoaS S Protein of unknown function (DUF2975)
IOOILHMJ_01950 4.4e-30 yozG K Transcriptional regulator
IOOILHMJ_01951 1.1e-147 yoaT S Protein of unknown function (DUF817)
IOOILHMJ_01952 1.5e-158 yoaU K LysR substrate binding domain
IOOILHMJ_01953 3.7e-157 yijE EG EamA-like transporter family
IOOILHMJ_01954 5.4e-77 yoaW
IOOILHMJ_01955 3.6e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
IOOILHMJ_01956 2.4e-167 bla 3.5.2.6 V beta-lactamase
IOOILHMJ_01959 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
IOOILHMJ_01960 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
IOOILHMJ_01961 4.2e-13 S YolD-like protein
IOOILHMJ_01962 1.3e-40
IOOILHMJ_01963 1.7e-47
IOOILHMJ_01964 9.7e-85 S SMI1-KNR4 cell-wall
IOOILHMJ_01965 3e-310 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOOILHMJ_01966 1.7e-102 yokH G SMI1 / KNR4 family
IOOILHMJ_01967 7.8e-274 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
IOOILHMJ_01968 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
IOOILHMJ_01969 5.1e-133 yobQ K helix_turn_helix, arabinose operon control protein
IOOILHMJ_01970 1.2e-16 yobR 2.3.1.1 J FR47-like protein
IOOILHMJ_01971 1e-80 yobS K Transcriptional regulator
IOOILHMJ_01972 2.8e-128 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
IOOILHMJ_01973 2.7e-85 yobU K Bacterial transcription activator, effector binding domain
IOOILHMJ_01974 1.2e-169 yobV K WYL domain
IOOILHMJ_01975 1.1e-92 yobW
IOOILHMJ_01976 1e-51 czrA K transcriptional
IOOILHMJ_01977 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IOOILHMJ_01978 1.5e-92 yozB S membrane
IOOILHMJ_01979 1.7e-142
IOOILHMJ_01980 6.1e-93 yocC
IOOILHMJ_01981 2.3e-184 yocD 3.4.17.13 V peptidase S66
IOOILHMJ_01982 6.9e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IOOILHMJ_01983 1.9e-195 desK 2.7.13.3 T Histidine kinase
IOOILHMJ_01984 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOOILHMJ_01986 3.3e-110 yocH CBM50 M COG1388 FOG LysM repeat
IOOILHMJ_01987 0.0 recQ 3.6.4.12 L DNA helicase
IOOILHMJ_01989 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOOILHMJ_01990 7.4e-83 dksA T general stress protein
IOOILHMJ_01991 5.4e-53 yocL
IOOILHMJ_01992 6.2e-32
IOOILHMJ_01993 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
IOOILHMJ_01994 1.1e-40 yozN
IOOILHMJ_01995 1.9e-36 yocN
IOOILHMJ_01996 4.2e-56 yozO S Bacterial PH domain
IOOILHMJ_01997 2.7e-31 yozC
IOOILHMJ_01998 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
IOOILHMJ_01999 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
IOOILHMJ_02000 6e-165 sodA 1.15.1.1 P Superoxide dismutase
IOOILHMJ_02001 2.2e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IOOILHMJ_02002 1.9e-167 yocS S -transporter
IOOILHMJ_02003 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IOOILHMJ_02004 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IOOILHMJ_02005 0.0 yojO P Von Willebrand factor
IOOILHMJ_02006 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
IOOILHMJ_02007 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IOOILHMJ_02008 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IOOILHMJ_02009 6.9e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
IOOILHMJ_02010 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOOILHMJ_02012 6.1e-244 norM V Multidrug efflux pump
IOOILHMJ_02013 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOOILHMJ_02014 2.1e-125 yojG S deacetylase
IOOILHMJ_02015 2.2e-60 yojF S Protein of unknown function (DUF1806)
IOOILHMJ_02016 1.6e-42
IOOILHMJ_02017 6.6e-162 rarD S -transporter
IOOILHMJ_02018 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
IOOILHMJ_02019 1.3e-08
IOOILHMJ_02020 1.7e-206 gntP EG COG2610 H gluconate symporter and related permeases
IOOILHMJ_02021 2.3e-63 yodA S tautomerase
IOOILHMJ_02022 5.7e-55 yodB K transcriptional
IOOILHMJ_02023 1.4e-107 yodC C nitroreductase
IOOILHMJ_02024 3.6e-111 mhqD S Carboxylesterase
IOOILHMJ_02025 3.5e-171 yodE E COG0346 Lactoylglutathione lyase and related lyases
IOOILHMJ_02026 1.4e-27 S Protein of unknown function (DUF3311)
IOOILHMJ_02027 2.3e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOOILHMJ_02028 1.4e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IOOILHMJ_02029 1.8e-127 yodH Q Methyltransferase
IOOILHMJ_02030 1.5e-23 yodI
IOOILHMJ_02031 9.4e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IOOILHMJ_02032 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IOOILHMJ_02033 5.3e-09
IOOILHMJ_02034 3.6e-54 yodL S YodL-like
IOOILHMJ_02035 7.8e-106 yodM 3.6.1.27 I Acid phosphatase homologues
IOOILHMJ_02036 2.8e-24 yozD S YozD-like protein
IOOILHMJ_02038 1.6e-123 yodN
IOOILHMJ_02039 1.4e-36 yozE S Belongs to the UPF0346 family
IOOILHMJ_02040 2.9e-47 yokU S YokU-like protein, putative antitoxin
IOOILHMJ_02041 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
IOOILHMJ_02042 1.7e-151 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
IOOILHMJ_02043 1.6e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
IOOILHMJ_02044 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IOOILHMJ_02045 7.1e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IOOILHMJ_02046 9.9e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOOILHMJ_02048 1.8e-144 yiiD K acetyltransferase
IOOILHMJ_02049 2.5e-255 cgeD M maturation of the outermost layer of the spore
IOOILHMJ_02050 4.5e-38 cgeC
IOOILHMJ_02051 3.1e-63 cgeA
IOOILHMJ_02052 9.1e-178 cgeB S Spore maturation protein
IOOILHMJ_02053 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
IOOILHMJ_02054 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
IOOILHMJ_02055 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IOOILHMJ_02056 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOOILHMJ_02057 1.6e-70 ypoP K transcriptional
IOOILHMJ_02058 3.2e-221 mepA V MATE efflux family protein
IOOILHMJ_02059 5.5e-29 ypmT S Uncharacterized ympT
IOOILHMJ_02060 3.2e-98 ypmS S protein conserved in bacteria
IOOILHMJ_02061 1.4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
IOOILHMJ_02062 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IOOILHMJ_02063 3.1e-40 ypmP S Protein of unknown function (DUF2535)
IOOILHMJ_02064 8.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IOOILHMJ_02065 1.2e-180 pspF K Transcriptional regulator
IOOILHMJ_02066 4.2e-110 hlyIII S protein, Hemolysin III
IOOILHMJ_02067 5.3e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IOOILHMJ_02068 2.1e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOOILHMJ_02069 9e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOOILHMJ_02070 2.8e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IOOILHMJ_02071 7.8e-114 ypjP S YpjP-like protein
IOOILHMJ_02072 1.1e-141 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
IOOILHMJ_02073 1.7e-75 yphP S Belongs to the UPF0403 family
IOOILHMJ_02074 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IOOILHMJ_02075 1e-198 L COG3666 Transposase and inactivated derivatives
IOOILHMJ_02076 2e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
IOOILHMJ_02077 2.5e-104 ypgQ S phosphohydrolase
IOOILHMJ_02078 6.8e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IOOILHMJ_02079 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IOOILHMJ_02080 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IOOILHMJ_02081 7.9e-31 cspD K Cold-shock protein
IOOILHMJ_02082 3.8e-16 degR
IOOILHMJ_02083 1.4e-30 S Protein of unknown function (DUF2564)
IOOILHMJ_02084 1.1e-28 ypeQ S Zinc-finger
IOOILHMJ_02085 3.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
IOOILHMJ_02086 1.1e-104 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IOOILHMJ_02087 4.6e-67 rnhA 3.1.26.4 L Ribonuclease
IOOILHMJ_02089 6.3e-165 polA 2.7.7.7 L 5'3' exonuclease
IOOILHMJ_02090 2e-07
IOOILHMJ_02091 3.8e-38 ypbS S Protein of unknown function (DUF2533)
IOOILHMJ_02092 0.0 ypbR S Dynamin family
IOOILHMJ_02094 5.1e-87 ypbQ S protein conserved in bacteria
IOOILHMJ_02095 3.1e-206 bcsA Q Naringenin-chalcone synthase
IOOILHMJ_02096 1.2e-225 pbuX F xanthine
IOOILHMJ_02097 1.7e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOOILHMJ_02098 1.8e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IOOILHMJ_02099 8.6e-163 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IOOILHMJ_02100 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
IOOILHMJ_02101 1.9e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
IOOILHMJ_02102 7.4e-186 ptxS K transcriptional
IOOILHMJ_02103 9.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IOOILHMJ_02104 2.8e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_02105 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
IOOILHMJ_02107 3.5e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IOOILHMJ_02108 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOOILHMJ_02109 2.8e-91 ypsA S Belongs to the UPF0398 family
IOOILHMJ_02110 2.2e-232 yprB L RNase_H superfamily
IOOILHMJ_02111 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IOOILHMJ_02112 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
IOOILHMJ_02113 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
IOOILHMJ_02114 1e-47 yppG S YppG-like protein
IOOILHMJ_02116 1.2e-11 yppE S Bacterial domain of unknown function (DUF1798)
IOOILHMJ_02119 5.4e-186 yppC S Protein of unknown function (DUF2515)
IOOILHMJ_02120 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOOILHMJ_02121 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
IOOILHMJ_02122 5.2e-92 ypoC
IOOILHMJ_02123 6.4e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOOILHMJ_02124 5.7e-129 dnaD L DNA replication protein DnaD
IOOILHMJ_02125 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
IOOILHMJ_02126 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IOOILHMJ_02127 4.9e-79 ypmB S protein conserved in bacteria
IOOILHMJ_02128 6.7e-23 ypmA S Protein of unknown function (DUF4264)
IOOILHMJ_02129 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IOOILHMJ_02130 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IOOILHMJ_02131 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IOOILHMJ_02132 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IOOILHMJ_02133 4.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOOILHMJ_02134 2.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOOILHMJ_02135 1.3e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
IOOILHMJ_02136 3.4e-129 bshB1 S proteins, LmbE homologs
IOOILHMJ_02137 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
IOOILHMJ_02138 3.5e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOOILHMJ_02139 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
IOOILHMJ_02140 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
IOOILHMJ_02141 2.3e-142 ypjB S sporulation protein
IOOILHMJ_02142 1.1e-96 ypjA S membrane
IOOILHMJ_02143 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
IOOILHMJ_02144 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
IOOILHMJ_02145 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
IOOILHMJ_02146 1.2e-76 ypiF S Protein of unknown function (DUF2487)
IOOILHMJ_02147 2.8e-99 ypiB S Belongs to the UPF0302 family
IOOILHMJ_02148 5.5e-231 S COG0457 FOG TPR repeat
IOOILHMJ_02149 1.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOOILHMJ_02150 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IOOILHMJ_02151 8.4e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOOILHMJ_02152 6.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOOILHMJ_02153 7.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOOILHMJ_02154 2.3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IOOILHMJ_02155 2.8e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IOOILHMJ_02156 1.4e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOOILHMJ_02157 1.8e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOOILHMJ_02158 3e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IOOILHMJ_02159 8.4e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOOILHMJ_02160 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOOILHMJ_02161 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
IOOILHMJ_02162 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IOOILHMJ_02163 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOOILHMJ_02164 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IOOILHMJ_02165 4.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IOOILHMJ_02166 1.1e-33 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IOOILHMJ_02167 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
IOOILHMJ_02168 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOOILHMJ_02169 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IOOILHMJ_02170 1.5e-135 yphF
IOOILHMJ_02171 1.6e-18 yphE S Protein of unknown function (DUF2768)
IOOILHMJ_02172 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IOOILHMJ_02173 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IOOILHMJ_02174 1.6e-28 ypzH
IOOILHMJ_02175 2.5e-161 seaA S YIEGIA protein
IOOILHMJ_02176 9.6e-101 yphA
IOOILHMJ_02177 1e-07 S YpzI-like protein
IOOILHMJ_02178 2.9e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOOILHMJ_02179 3.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
IOOILHMJ_02180 3e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IOOILHMJ_02181 1.8e-23 S Family of unknown function (DUF5359)
IOOILHMJ_02182 2.1e-109 ypfA M Flagellar protein YcgR
IOOILHMJ_02183 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
IOOILHMJ_02184 5.7e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
IOOILHMJ_02185 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
IOOILHMJ_02186 6.7e-176 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
IOOILHMJ_02187 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IOOILHMJ_02188 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IOOILHMJ_02189 1.3e-145 ypbG S Calcineurin-like phosphoesterase superfamily domain
IOOILHMJ_02190 8.2e-81 ypbF S Protein of unknown function (DUF2663)
IOOILHMJ_02191 9.1e-77 ypbE M Lysin motif
IOOILHMJ_02192 2.4e-99 ypbD S metal-dependent membrane protease
IOOILHMJ_02193 7.8e-285 recQ 3.6.4.12 L DNA helicase
IOOILHMJ_02194 2.3e-198 ypbB 5.1.3.1 S protein conserved in bacteria
IOOILHMJ_02195 4.7e-41 fer C Ferredoxin
IOOILHMJ_02196 9.9e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOOILHMJ_02197 1.3e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOOILHMJ_02198 7.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IOOILHMJ_02199 5.2e-193 rsiX
IOOILHMJ_02200 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_02201 0.0 resE 2.7.13.3 T Histidine kinase
IOOILHMJ_02202 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_02203 2.6e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IOOILHMJ_02204 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
IOOILHMJ_02205 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IOOILHMJ_02206 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOOILHMJ_02207 7.1e-87 spmB S Spore maturation protein
IOOILHMJ_02208 3.5e-103 spmA S Spore maturation protein
IOOILHMJ_02209 6.1e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
IOOILHMJ_02210 7.6e-97 ypuI S Protein of unknown function (DUF3907)
IOOILHMJ_02211 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOOILHMJ_02212 3.7e-126 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOOILHMJ_02213 7.9e-91 ypuF S Domain of unknown function (DUF309)
IOOILHMJ_02214 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOOILHMJ_02215 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IOOILHMJ_02216 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IOOILHMJ_02217 7.4e-115 ribE 2.5.1.9 H Riboflavin synthase
IOOILHMJ_02218 3.8e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IOOILHMJ_02219 7.8e-55 ypuD
IOOILHMJ_02220 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IOOILHMJ_02221 7.3e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
IOOILHMJ_02223 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOOILHMJ_02224 1.4e-148 ypuA S Secreted protein
IOOILHMJ_02225 2e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOOILHMJ_02226 1.4e-273 spoVAF EG Stage V sporulation protein AF
IOOILHMJ_02227 1.4e-110 spoVAEA S stage V sporulation protein
IOOILHMJ_02228 2.2e-57 spoVAEB S stage V sporulation protein
IOOILHMJ_02229 9e-192 spoVAD I Stage V sporulation protein AD
IOOILHMJ_02230 2.3e-78 spoVAC S stage V sporulation protein AC
IOOILHMJ_02231 1e-67 spoVAB S Stage V sporulation protein AB
IOOILHMJ_02232 3.7e-111 spoVAA S Stage V sporulation protein AA
IOOILHMJ_02233 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOOILHMJ_02234 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IOOILHMJ_02235 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
IOOILHMJ_02236 3.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
IOOILHMJ_02237 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IOOILHMJ_02238 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOOILHMJ_02239 2.6e-166 xerD L recombinase XerD
IOOILHMJ_02240 3.7e-37 S Protein of unknown function (DUF4227)
IOOILHMJ_02241 2.4e-80 fur P Belongs to the Fur family
IOOILHMJ_02242 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IOOILHMJ_02243 1.9e-30 yqkK
IOOILHMJ_02244 6.1e-241 mleA 1.1.1.38 C malic enzyme
IOOILHMJ_02245 9.1e-235 mleN C Na H antiporter
IOOILHMJ_02246 1.4e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
IOOILHMJ_02247 8e-185 ansA 3.5.1.1 EJ L-asparaginase
IOOILHMJ_02248 4.5e-58 ansR K Transcriptional regulator
IOOILHMJ_02249 5.8e-219 yqxK 3.6.4.12 L DNA helicase
IOOILHMJ_02250 5.8e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
IOOILHMJ_02252 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
IOOILHMJ_02253 3.1e-12 yqkE S Protein of unknown function (DUF3886)
IOOILHMJ_02254 2.4e-170 yqkD S COG1073 Hydrolases of the alpha beta superfamily
IOOILHMJ_02255 9.4e-39 yqkC S Protein of unknown function (DUF2552)
IOOILHMJ_02256 6.2e-54 yqkB S Belongs to the HesB IscA family
IOOILHMJ_02257 6.3e-193 yqkA K GrpB protein
IOOILHMJ_02258 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
IOOILHMJ_02259 5.3e-86 yqjY K acetyltransferase
IOOILHMJ_02260 5.7e-50 S YolD-like protein
IOOILHMJ_02261 1.6e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOOILHMJ_02263 4.2e-223 yqjV G Major Facilitator Superfamily
IOOILHMJ_02265 1e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOOILHMJ_02266 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
IOOILHMJ_02267 4.6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IOOILHMJ_02268 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_02269 1.6e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
IOOILHMJ_02270 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOOILHMJ_02271 0.0 rocB E arginine degradation protein
IOOILHMJ_02272 4.1e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IOOILHMJ_02273 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOOILHMJ_02274 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOOILHMJ_02275 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOOILHMJ_02276 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOOILHMJ_02277 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOOILHMJ_02278 2.9e-232 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOOILHMJ_02279 8.1e-24 yqzJ
IOOILHMJ_02280 8.5e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOOILHMJ_02281 2.1e-137 yqjF S Uncharacterized conserved protein (COG2071)
IOOILHMJ_02282 6.2e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
IOOILHMJ_02283 5e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOOILHMJ_02284 2.3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
IOOILHMJ_02286 1.4e-98 yqjB S protein conserved in bacteria
IOOILHMJ_02287 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
IOOILHMJ_02288 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IOOILHMJ_02289 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
IOOILHMJ_02290 9e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
IOOILHMJ_02291 9.3e-77 yqiW S Belongs to the UPF0403 family
IOOILHMJ_02292 7.5e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IOOILHMJ_02293 6.7e-207 norA EGP Major facilitator Superfamily
IOOILHMJ_02294 1.9e-150 bmrR K helix_turn_helix, mercury resistance
IOOILHMJ_02295 4.4e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOOILHMJ_02296 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOOILHMJ_02297 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOOILHMJ_02298 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOOILHMJ_02299 7.9e-202 buk 2.7.2.7 C Belongs to the acetokinase family
IOOILHMJ_02300 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
IOOILHMJ_02301 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
IOOILHMJ_02302 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
IOOILHMJ_02303 4e-34 yqzF S Protein of unknown function (DUF2627)
IOOILHMJ_02304 3.9e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IOOILHMJ_02305 5.3e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
IOOILHMJ_02306 6.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
IOOILHMJ_02307 8.2e-210 mmgC I acyl-CoA dehydrogenase
IOOILHMJ_02308 1.7e-154 hbdA 1.1.1.157 I Dehydrogenase
IOOILHMJ_02309 4.2e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
IOOILHMJ_02310 4.1e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOOILHMJ_02311 1.2e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
IOOILHMJ_02312 8.6e-26
IOOILHMJ_02313 1.4e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IOOILHMJ_02315 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IOOILHMJ_02316 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
IOOILHMJ_02317 5.5e-306 recN L May be involved in recombinational repair of damaged DNA
IOOILHMJ_02318 5.6e-77 argR K Regulates arginine biosynthesis genes
IOOILHMJ_02319 1.6e-152 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
IOOILHMJ_02320 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOOILHMJ_02321 1.7e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOOILHMJ_02322 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOOILHMJ_02323 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOOILHMJ_02324 1.3e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOOILHMJ_02325 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOOILHMJ_02326 2.1e-67 yqhY S protein conserved in bacteria
IOOILHMJ_02327 3.4e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IOOILHMJ_02328 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOOILHMJ_02329 9.9e-91 spoIIIAH S SpoIIIAH-like protein
IOOILHMJ_02330 2.3e-109 spoIIIAG S stage III sporulation protein AG
IOOILHMJ_02331 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
IOOILHMJ_02332 1.3e-197 spoIIIAE S stage III sporulation protein AE
IOOILHMJ_02333 2.3e-58 spoIIIAD S Stage III sporulation protein AD
IOOILHMJ_02334 7.6e-29 spoIIIAC S stage III sporulation protein AC
IOOILHMJ_02335 1.1e-84 spoIIIAB S Stage III sporulation protein
IOOILHMJ_02336 1.2e-171 spoIIIAA S stage III sporulation protein AA
IOOILHMJ_02337 7.9e-37 yqhV S Protein of unknown function (DUF2619)
IOOILHMJ_02338 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOOILHMJ_02339 7.5e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IOOILHMJ_02340 4.2e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
IOOILHMJ_02341 8.6e-93 yqhR S Conserved membrane protein YqhR
IOOILHMJ_02342 8e-174 yqhQ S Protein of unknown function (DUF1385)
IOOILHMJ_02343 2.2e-61 yqhP
IOOILHMJ_02344 1.8e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
IOOILHMJ_02345 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IOOILHMJ_02346 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IOOILHMJ_02347 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
IOOILHMJ_02348 2.9e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IOOILHMJ_02349 4.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IOOILHMJ_02350 1.4e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
IOOILHMJ_02351 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IOOILHMJ_02352 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
IOOILHMJ_02353 1.2e-24 sinI S Anti-repressor SinI
IOOILHMJ_02354 7e-54 sinR K transcriptional
IOOILHMJ_02355 1.9e-141 tasA S Cell division protein FtsN
IOOILHMJ_02356 2.8e-57 sipW 3.4.21.89 U Signal peptidase
IOOILHMJ_02357 1.3e-110 yqxM
IOOILHMJ_02358 2.6e-52 yqzG S Protein of unknown function (DUF3889)
IOOILHMJ_02359 1.4e-26 yqzE S YqzE-like protein
IOOILHMJ_02360 8.8e-44 S ComG operon protein 7
IOOILHMJ_02361 2e-35 comGF U Putative Competence protein ComGF
IOOILHMJ_02362 5.9e-58 comGE
IOOILHMJ_02363 1.8e-69 gspH NU protein transport across the cell outer membrane
IOOILHMJ_02364 6.8e-47 comGC U Required for transformation and DNA binding
IOOILHMJ_02365 6.2e-172 comGB NU COG1459 Type II secretory pathway, component PulF
IOOILHMJ_02366 6.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IOOILHMJ_02367 1.4e-173 corA P Mg2 transporter protein
IOOILHMJ_02368 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IOOILHMJ_02369 8.6e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOOILHMJ_02371 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
IOOILHMJ_02372 1.8e-37 yqgY S Protein of unknown function (DUF2626)
IOOILHMJ_02373 4.7e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IOOILHMJ_02374 8.9e-23 yqgW S Protein of unknown function (DUF2759)
IOOILHMJ_02375 6.9e-50 yqgV S Thiamine-binding protein
IOOILHMJ_02376 1.3e-196 yqgU
IOOILHMJ_02377 7.4e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
IOOILHMJ_02378 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IOOILHMJ_02379 5.2e-181 glcK 2.7.1.2 G Glucokinase
IOOILHMJ_02380 3.1e-33 yqgQ S Protein conserved in bacteria
IOOILHMJ_02381 5.6e-238 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IOOILHMJ_02382 2.5e-09 yqgO
IOOILHMJ_02383 3.9e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOOILHMJ_02384 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOOILHMJ_02385 6.1e-197 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
IOOILHMJ_02387 9.2e-51 yqzD
IOOILHMJ_02388 7.3e-72 yqzC S YceG-like family
IOOILHMJ_02389 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOOILHMJ_02390 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOOILHMJ_02391 4.4e-158 pstA P Phosphate transport system permease
IOOILHMJ_02392 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
IOOILHMJ_02393 1.8e-143 pstS P Phosphate
IOOILHMJ_02394 0.0 pbpA 3.4.16.4 M penicillin-binding protein
IOOILHMJ_02395 2.5e-231 yqgE EGP Major facilitator superfamily
IOOILHMJ_02396 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
IOOILHMJ_02397 2e-72 yqgC S protein conserved in bacteria
IOOILHMJ_02398 3.9e-131 yqgB S Protein of unknown function (DUF1189)
IOOILHMJ_02399 1.2e-46 yqfZ M LysM domain
IOOILHMJ_02400 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IOOILHMJ_02401 4.3e-62 yqfX S membrane
IOOILHMJ_02402 1.3e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
IOOILHMJ_02403 5.4e-77 zur P Belongs to the Fur family
IOOILHMJ_02404 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IOOILHMJ_02405 2.1e-36 yqfT S Protein of unknown function (DUF2624)
IOOILHMJ_02406 5.7e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOOILHMJ_02407 8.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOOILHMJ_02409 3.8e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IOOILHMJ_02410 1.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOOILHMJ_02411 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
IOOILHMJ_02412 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
IOOILHMJ_02413 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOOILHMJ_02414 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOOILHMJ_02415 1.7e-87 yaiI S Belongs to the UPF0178 family
IOOILHMJ_02416 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOOILHMJ_02417 4.5e-112 ccpN K CBS domain
IOOILHMJ_02418 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IOOILHMJ_02419 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IOOILHMJ_02420 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
IOOILHMJ_02421 8.4e-19 S YqzL-like protein
IOOILHMJ_02422 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOOILHMJ_02423 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IOOILHMJ_02424 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IOOILHMJ_02425 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOOILHMJ_02426 0.0 yqfF S membrane-associated HD superfamily hydrolase
IOOILHMJ_02428 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
IOOILHMJ_02429 5.6e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
IOOILHMJ_02430 2.7e-45 yqfC S sporulation protein YqfC
IOOILHMJ_02431 2.3e-24 yqfB
IOOILHMJ_02432 1.5e-119 yqfA S UPF0365 protein
IOOILHMJ_02433 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
IOOILHMJ_02434 2.5e-61 yqeY S Yqey-like protein
IOOILHMJ_02435 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IOOILHMJ_02436 2.6e-156 yqeW P COG1283 Na phosphate symporter
IOOILHMJ_02437 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
IOOILHMJ_02438 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOOILHMJ_02439 5.4e-175 prmA J Methylates ribosomal protein L11
IOOILHMJ_02440 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOOILHMJ_02441 0.0 dnaK O Heat shock 70 kDa protein
IOOILHMJ_02442 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOOILHMJ_02443 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOOILHMJ_02444 2.2e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
IOOILHMJ_02445 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOOILHMJ_02446 7.2e-53 yqxA S Protein of unknown function (DUF3679)
IOOILHMJ_02447 7.6e-222 spoIIP M stage II sporulation protein P
IOOILHMJ_02448 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IOOILHMJ_02449 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
IOOILHMJ_02450 2.1e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
IOOILHMJ_02451 4.1e-15 S YqzM-like protein
IOOILHMJ_02452 0.0 comEC S Competence protein ComEC
IOOILHMJ_02453 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
IOOILHMJ_02454 3.6e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
IOOILHMJ_02455 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOOILHMJ_02456 6.5e-139 yqeM Q Methyltransferase
IOOILHMJ_02457 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOOILHMJ_02458 1.1e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IOOILHMJ_02459 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOOILHMJ_02460 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
IOOILHMJ_02461 3.9e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOOILHMJ_02462 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IOOILHMJ_02463 5.3e-95 yqeG S hydrolase of the HAD superfamily
IOOILHMJ_02465 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
IOOILHMJ_02466 5.4e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IOOILHMJ_02467 1.3e-103 yqeD S SNARE associated Golgi protein
IOOILHMJ_02468 9.4e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
IOOILHMJ_02469 1.5e-129 yqeB
IOOILHMJ_02470 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
IOOILHMJ_02471 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOOILHMJ_02473 2e-68 psiE S Protein PsiE homolog
IOOILHMJ_02474 1.2e-233 yrkQ T Histidine kinase
IOOILHMJ_02475 2.2e-125 T Transcriptional regulator
IOOILHMJ_02476 7.7e-222 yrkO P Protein of unknown function (DUF418)
IOOILHMJ_02477 6.9e-101 yrkN K Acetyltransferase (GNAT) family
IOOILHMJ_02478 2.4e-59 ykvN K HxlR-like helix-turn-helix
IOOILHMJ_02479 2e-132 IQ Enoyl-(Acyl carrier protein) reductase
IOOILHMJ_02480 2.3e-27 S SMI1-KNR4 cell-wall
IOOILHMJ_02481 1.1e-30
IOOILHMJ_02483 9.8e-128 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IOOILHMJ_02484 1.1e-66 S Bacteriophage holin family
IOOILHMJ_02485 2.1e-14 xepA
IOOILHMJ_02486 9.9e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
IOOILHMJ_02487 6.9e-90 K Transcriptional regulator PadR-like family
IOOILHMJ_02488 2.9e-96 adk 2.7.4.3 F adenylate kinase activity
IOOILHMJ_02490 4.9e-90 yqaB E IrrE N-terminal-like domain
IOOILHMJ_02491 4.1e-12 cisA2 L recombinase activity
IOOILHMJ_02492 7.4e-97 ywrO S Flavodoxin-like fold
IOOILHMJ_02493 1.2e-77 S Protein of unknown function with HXXEE motif
IOOILHMJ_02494 4.7e-62 hosA K helix_turn_helix multiple antibiotic resistance protein
IOOILHMJ_02495 5.4e-60 2.8.1.7, 4.4.1.16 P Rhodanese Homology Domain
IOOILHMJ_02497 1e-191 S Aspartate phosphatase response regulator
IOOILHMJ_02498 2.6e-168 yobL S Bacterial EndoU nuclease
IOOILHMJ_02499 5.7e-48
IOOILHMJ_02500 7.3e-25
IOOILHMJ_02502 4.9e-11 S SMI1 / KNR4 family
IOOILHMJ_02503 2.8e-118 EGP Necrosis inducing protein (NPP1)
IOOILHMJ_02504 5.8e-149 bltR K helix_turn_helix, mercury resistance
IOOILHMJ_02505 3.7e-208 blt EGP Major facilitator Superfamily
IOOILHMJ_02506 9.1e-83 bltD 2.3.1.57 K FR47-like protein
IOOILHMJ_02507 1.5e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IOOILHMJ_02508 3.9e-16 S YrzO-like protein
IOOILHMJ_02509 1.3e-168 yrdR EG EamA-like transporter family
IOOILHMJ_02510 8.6e-159 yrdQ K Transcriptional regulator
IOOILHMJ_02511 5.8e-194 trkA P Oxidoreductase
IOOILHMJ_02512 2.5e-151 czcD P COG1230 Co Zn Cd efflux system component
IOOILHMJ_02513 5e-66 yodA S tautomerase
IOOILHMJ_02514 1.2e-160 gltR K LysR substrate binding domain
IOOILHMJ_02515 3e-227 brnQ E Component of the transport system for branched-chain amino acids
IOOILHMJ_02516 2.1e-49 azlD E Branched-chain amino acid transport protein (AzlD)
IOOILHMJ_02517 7.4e-138 azlC E AzlC protein
IOOILHMJ_02518 6.9e-78 bkdR K helix_turn_helix ASNC type
IOOILHMJ_02519 4.5e-18 yrdF K ribonuclease inhibitor
IOOILHMJ_02520 1.7e-221 cypA C Cytochrome P450
IOOILHMJ_02521 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
IOOILHMJ_02522 2.6e-54 S Protein of unknown function (DUF2568)
IOOILHMJ_02524 5.4e-89 yrdA S DinB family
IOOILHMJ_02525 1.3e-164 aadK G Streptomycin adenylyltransferase
IOOILHMJ_02526 1.6e-191 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IOOILHMJ_02527 2.4e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOOILHMJ_02528 1.2e-123 yrpD S Domain of unknown function, YrpD
IOOILHMJ_02529 3.5e-116 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IOOILHMJ_02530 5.9e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_02531 1.9e-186 yrpG C Aldo/keto reductase family
IOOILHMJ_02532 5e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IOOILHMJ_02533 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOOILHMJ_02534 3.1e-147 S Alpha beta hydrolase
IOOILHMJ_02535 1.7e-60 T sh3 domain protein
IOOILHMJ_02536 2.4e-61 T sh3 domain protein
IOOILHMJ_02537 3.8e-66 E Glyoxalase-like domain
IOOILHMJ_02538 1.5e-36 yraG
IOOILHMJ_02539 6.4e-63 yraF M Spore coat protein
IOOILHMJ_02540 2.3e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IOOILHMJ_02541 2.2e-25 yraE
IOOILHMJ_02542 1.8e-47 yraD M Spore coat protein
IOOILHMJ_02543 9.6e-47 yraB K helix_turn_helix, mercury resistance
IOOILHMJ_02544 1.1e-24 yphJ 4.1.1.44 S peroxiredoxin activity
IOOILHMJ_02545 8.1e-196 adhA 1.1.1.1 C alcohol dehydrogenase
IOOILHMJ_02546 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
IOOILHMJ_02547 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
IOOILHMJ_02548 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IOOILHMJ_02549 1.4e-115 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IOOILHMJ_02550 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
IOOILHMJ_02551 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
IOOILHMJ_02552 0.0 levR K PTS system fructose IIA component
IOOILHMJ_02553 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
IOOILHMJ_02554 4.4e-104 yrhP E LysE type translocator
IOOILHMJ_02555 1e-148 yrhO K Archaeal transcriptional regulator TrmB
IOOILHMJ_02556 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_02557 9.4e-150 rsiV S Protein of unknown function (DUF3298)
IOOILHMJ_02558 0.0 yrhL I Acyltransferase family
IOOILHMJ_02559 3.4e-43 yrhK S YrhK-like protein
IOOILHMJ_02560 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IOOILHMJ_02561 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
IOOILHMJ_02562 9.3e-95 yrhH Q methyltransferase
IOOILHMJ_02565 1.8e-142 focA P Formate nitrite
IOOILHMJ_02566 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
IOOILHMJ_02567 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
IOOILHMJ_02568 5.4e-78 yrhD S Protein of unknown function (DUF1641)
IOOILHMJ_02569 1e-34 yrhC S YrhC-like protein
IOOILHMJ_02570 4.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IOOILHMJ_02571 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
IOOILHMJ_02572 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOOILHMJ_02573 2.9e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
IOOILHMJ_02574 1e-25 yrzA S Protein of unknown function (DUF2536)
IOOILHMJ_02575 7.1e-63 yrrS S Protein of unknown function (DUF1510)
IOOILHMJ_02576 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
IOOILHMJ_02577 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOOILHMJ_02578 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IOOILHMJ_02579 1e-245 yegQ O COG0826 Collagenase and related proteases
IOOILHMJ_02580 6.2e-171 yegQ O Peptidase U32
IOOILHMJ_02581 5e-119 yrrM 2.1.1.104 S O-methyltransferase
IOOILHMJ_02582 1.1e-182 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOOILHMJ_02583 1.2e-45 yrzB S Belongs to the UPF0473 family
IOOILHMJ_02584 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOOILHMJ_02585 1.7e-41 yrzL S Belongs to the UPF0297 family
IOOILHMJ_02586 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOOILHMJ_02587 2.3e-169 yrrI S AI-2E family transporter
IOOILHMJ_02588 4.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IOOILHMJ_02589 3.3e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
IOOILHMJ_02590 8e-109 gluC P ABC transporter
IOOILHMJ_02591 7.6e-107 glnP P ABC transporter
IOOILHMJ_02592 8e-08 S Protein of unknown function (DUF3918)
IOOILHMJ_02593 9.8e-31 yrzR
IOOILHMJ_02594 2.5e-80 yrrD S protein conserved in bacteria
IOOILHMJ_02595 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOOILHMJ_02596 1.4e-15 S COG0457 FOG TPR repeat
IOOILHMJ_02597 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOOILHMJ_02598 1.3e-210 iscS 2.8.1.7 E Cysteine desulfurase
IOOILHMJ_02599 1.2e-70 cymR K Transcriptional regulator
IOOILHMJ_02600 5.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IOOILHMJ_02601 1e-134 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IOOILHMJ_02602 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IOOILHMJ_02603 1.8e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
IOOILHMJ_02605 4.8e-261 lytH 3.5.1.28 M COG3103 SH3 domain protein
IOOILHMJ_02606 8.5e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOOILHMJ_02607 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOOILHMJ_02608 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOOILHMJ_02609 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IOOILHMJ_02610 6.7e-48 yrvD S Lipopolysaccharide assembly protein A domain
IOOILHMJ_02611 6.6e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
IOOILHMJ_02612 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IOOILHMJ_02613 1.6e-48 yrzD S Post-transcriptional regulator
IOOILHMJ_02614 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOOILHMJ_02615 1.7e-111 yrbG S membrane
IOOILHMJ_02616 6.4e-73 yrzE S Protein of unknown function (DUF3792)
IOOILHMJ_02617 1.1e-38 yajC U Preprotein translocase subunit YajC
IOOILHMJ_02618 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOOILHMJ_02619 4.4e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IOOILHMJ_02620 1.6e-15 yrzS S Protein of unknown function (DUF2905)
IOOILHMJ_02621 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOOILHMJ_02622 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOOILHMJ_02623 4.8e-93 bofC S BofC C-terminal domain
IOOILHMJ_02624 4.5e-252 csbX EGP Major facilitator Superfamily
IOOILHMJ_02625 4.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IOOILHMJ_02626 2.1e-117 yrzF T serine threonine protein kinase
IOOILHMJ_02628 8.1e-52 S Family of unknown function (DUF5412)
IOOILHMJ_02629 9.1e-262 alsT E Sodium alanine symporter
IOOILHMJ_02630 4.7e-126 yebC K transcriptional regulatory protein
IOOILHMJ_02631 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOOILHMJ_02632 3.8e-154 safA M spore coat assembly protein SafA
IOOILHMJ_02633 3.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IOOILHMJ_02634 1.4e-153 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
IOOILHMJ_02635 7e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IOOILHMJ_02636 1.6e-227 nifS 2.8.1.7 E Cysteine desulfurase
IOOILHMJ_02637 7.9e-94 niaR S small molecule binding protein (contains 3H domain)
IOOILHMJ_02638 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
IOOILHMJ_02639 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
IOOILHMJ_02640 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOOILHMJ_02641 1.4e-104 spo0B T Sporulation initiation phospho-transferase B, C-terminal
IOOILHMJ_02642 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IOOILHMJ_02643 4.1e-56 ysxB J ribosomal protein
IOOILHMJ_02644 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IOOILHMJ_02645 5.9e-160 spoIVFB S Stage IV sporulation protein
IOOILHMJ_02646 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
IOOILHMJ_02647 2.5e-144 minD D Belongs to the ParA family
IOOILHMJ_02648 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IOOILHMJ_02649 1.4e-84 mreD M shape-determining protein
IOOILHMJ_02650 1.1e-156 mreC M Involved in formation and maintenance of cell shape
IOOILHMJ_02651 1.8e-184 mreB D Rod shape-determining protein MreB
IOOILHMJ_02652 1.7e-125 radC E Belongs to the UPF0758 family
IOOILHMJ_02653 2.8e-102 maf D septum formation protein Maf
IOOILHMJ_02654 1e-163 spoIIB S Sporulation related domain
IOOILHMJ_02655 7e-125 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IOOILHMJ_02656 6.9e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOOILHMJ_02657 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOOILHMJ_02658 1.6e-25
IOOILHMJ_02659 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IOOILHMJ_02660 3e-203 spoVID M stage VI sporulation protein D
IOOILHMJ_02661 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IOOILHMJ_02662 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
IOOILHMJ_02663 1.2e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IOOILHMJ_02664 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IOOILHMJ_02665 3.6e-146 hemX O cytochrome C
IOOILHMJ_02666 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IOOILHMJ_02667 5.4e-89 ysxD
IOOILHMJ_02668 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
IOOILHMJ_02669 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IOOILHMJ_02670 2.8e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
IOOILHMJ_02671 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOOILHMJ_02672 1.4e-221 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOOILHMJ_02673 5.1e-187 ysoA H Tetratricopeptide repeat
IOOILHMJ_02674 2.4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOOILHMJ_02675 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOOILHMJ_02676 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IOOILHMJ_02677 2.1e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IOOILHMJ_02678 7e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOOILHMJ_02679 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
IOOILHMJ_02680 0.0 ilvB 2.2.1.6 E Acetolactate synthase
IOOILHMJ_02682 1.1e-75 ysnE K acetyltransferase
IOOILHMJ_02683 8.5e-132 ysnF S protein conserved in bacteria
IOOILHMJ_02685 1.8e-92 ysnB S Phosphoesterase
IOOILHMJ_02686 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOOILHMJ_02687 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IOOILHMJ_02688 2.9e-196 gerM S COG5401 Spore germination protein
IOOILHMJ_02689 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOOILHMJ_02690 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
IOOILHMJ_02691 3.3e-30 gerE K Transcriptional regulator
IOOILHMJ_02692 1.9e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
IOOILHMJ_02693 2.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IOOILHMJ_02694 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IOOILHMJ_02695 2.4e-107 sdhC C succinate dehydrogenase
IOOILHMJ_02696 1.2e-79 yslB S Protein of unknown function (DUF2507)
IOOILHMJ_02697 1.4e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IOOILHMJ_02698 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOOILHMJ_02699 2e-52 trxA O Belongs to the thioredoxin family
IOOILHMJ_02700 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
IOOILHMJ_02702 9.3e-178 etfA C Electron transfer flavoprotein
IOOILHMJ_02703 1.7e-134 etfB C Electron transfer flavoprotein
IOOILHMJ_02704 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IOOILHMJ_02705 4e-99 fadR K Transcriptional regulator
IOOILHMJ_02706 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IOOILHMJ_02707 7.3e-68 yshE S membrane
IOOILHMJ_02708 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOOILHMJ_02709 0.0 polX L COG1796 DNA polymerase IV (family X)
IOOILHMJ_02710 1.3e-85 cvpA S membrane protein, required for colicin V production
IOOILHMJ_02711 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IOOILHMJ_02712 2.6e-169 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOOILHMJ_02713 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOOILHMJ_02714 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOOILHMJ_02715 7.7e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOOILHMJ_02716 3.8e-31 sspI S Belongs to the SspI family
IOOILHMJ_02717 5e-204 ysfB KT regulator
IOOILHMJ_02718 2.5e-256 glcD 1.1.3.15 C Glycolate oxidase subunit
IOOILHMJ_02719 1.3e-254 glcF C Glycolate oxidase
IOOILHMJ_02720 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
IOOILHMJ_02721 0.0 cstA T Carbon starvation protein
IOOILHMJ_02722 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
IOOILHMJ_02723 2.9e-143 araQ G transport system permease
IOOILHMJ_02724 2.7e-166 araP G carbohydrate transport
IOOILHMJ_02725 1.7e-251 araN G carbohydrate transport
IOOILHMJ_02726 2.7e-219 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IOOILHMJ_02727 5e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IOOILHMJ_02728 3.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IOOILHMJ_02729 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
IOOILHMJ_02730 2.3e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IOOILHMJ_02731 6.6e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IOOILHMJ_02732 1.3e-204 ysdC G COG1363 Cellulase M and related proteins
IOOILHMJ_02733 9.2e-68 ysdB S Sigma-w pathway protein YsdB
IOOILHMJ_02734 7.5e-45 ysdA S Membrane
IOOILHMJ_02735 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOOILHMJ_02736 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IOOILHMJ_02737 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOOILHMJ_02739 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IOOILHMJ_02740 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IOOILHMJ_02741 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
IOOILHMJ_02742 0.0 lytS 2.7.13.3 T Histidine kinase
IOOILHMJ_02743 7.3e-149 ysaA S HAD-hyrolase-like
IOOILHMJ_02744 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOOILHMJ_02745 4.2e-158 ytxC S YtxC-like family
IOOILHMJ_02746 5.6e-107 ytxB S SNARE associated Golgi protein
IOOILHMJ_02747 6.6e-173 dnaI L Primosomal protein DnaI
IOOILHMJ_02748 1.7e-265 dnaB L Membrane attachment protein
IOOILHMJ_02749 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOOILHMJ_02750 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IOOILHMJ_02751 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOOILHMJ_02752 9.9e-67 ytcD K Transcriptional regulator
IOOILHMJ_02753 2.4e-204 ytbD EGP Major facilitator Superfamily
IOOILHMJ_02754 2e-160 ytbE S reductase
IOOILHMJ_02755 6.4e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOOILHMJ_02756 1.1e-107 ytaF P Probably functions as a manganese efflux pump
IOOILHMJ_02757 1.5e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOOILHMJ_02758 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOOILHMJ_02759 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
IOOILHMJ_02760 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_02761 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
IOOILHMJ_02762 4.1e-242 icd 1.1.1.42 C isocitrate
IOOILHMJ_02763 3.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
IOOILHMJ_02764 4.7e-71 yeaL S membrane
IOOILHMJ_02765 7.6e-192 ytvI S sporulation integral membrane protein YtvI
IOOILHMJ_02766 2.5e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
IOOILHMJ_02767 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IOOILHMJ_02768 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOOILHMJ_02769 1.3e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IOOILHMJ_02770 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOOILHMJ_02771 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
IOOILHMJ_02772 0.0 dnaE 2.7.7.7 L DNA polymerase
IOOILHMJ_02773 3.2e-56 ytrH S Sporulation protein YtrH
IOOILHMJ_02774 8.2e-69 ytrI
IOOILHMJ_02775 9.2e-29
IOOILHMJ_02776 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
IOOILHMJ_02777 2.4e-47 ytpI S YtpI-like protein
IOOILHMJ_02778 1.8e-240 ytoI K transcriptional regulator containing CBS domains
IOOILHMJ_02779 2.9e-157 ytnM S membrane transporter protein
IOOILHMJ_02780 2.4e-234 ytnL 3.5.1.47 E hydrolase activity
IOOILHMJ_02781 2.9e-122 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
IOOILHMJ_02782 4.1e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOOILHMJ_02783 5.9e-42 ytnI O COG0695 Glutaredoxin and related proteins
IOOILHMJ_02784 1.2e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOOILHMJ_02785 1.9e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IOOILHMJ_02786 2.1e-118 tcyM U Binding-protein-dependent transport system inner membrane component
IOOILHMJ_02787 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
IOOILHMJ_02788 1.2e-143 tcyK M Bacterial periplasmic substrate-binding proteins
IOOILHMJ_02789 4.7e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
IOOILHMJ_02790 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
IOOILHMJ_02791 2.3e-170 ytlI K LysR substrate binding domain
IOOILHMJ_02792 1.7e-130 ytkL S Belongs to the UPF0173 family
IOOILHMJ_02793 2.5e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_02795 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
IOOILHMJ_02796 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOOILHMJ_02797 6.8e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IOOILHMJ_02798 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOOILHMJ_02799 5.9e-164 ytxK 2.1.1.72 L DNA methylase
IOOILHMJ_02800 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOOILHMJ_02801 2.5e-69 ytfJ S Sporulation protein YtfJ
IOOILHMJ_02802 8.1e-115 ytfI S Protein of unknown function (DUF2953)
IOOILHMJ_02803 2.1e-85 yteJ S RDD family
IOOILHMJ_02804 6.7e-179 sppA OU signal peptide peptidase SppA
IOOILHMJ_02805 1.1e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOOILHMJ_02806 0.0 ytcJ S amidohydrolase
IOOILHMJ_02807 1.1e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IOOILHMJ_02808 2e-29 sspB S spore protein
IOOILHMJ_02809 2.3e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOOILHMJ_02810 7.8e-208 iscS2 2.8.1.7 E Cysteine desulfurase
IOOILHMJ_02811 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
IOOILHMJ_02812 2.8e-270 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOOILHMJ_02813 3.8e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IOOILHMJ_02814 2.9e-108 yttP K Transcriptional regulator
IOOILHMJ_02815 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
IOOILHMJ_02816 9.6e-311 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
IOOILHMJ_02817 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOOILHMJ_02819 5.2e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOOILHMJ_02820 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IOOILHMJ_02821 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IOOILHMJ_02822 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
IOOILHMJ_02823 3.5e-224 acuC BQ histone deacetylase
IOOILHMJ_02824 1.4e-125 motS N Flagellar motor protein
IOOILHMJ_02825 2.1e-146 motA N flagellar motor
IOOILHMJ_02826 1.7e-182 ccpA K catabolite control protein A
IOOILHMJ_02827 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IOOILHMJ_02828 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
IOOILHMJ_02829 6.6e-17 ytxH S COG4980 Gas vesicle protein
IOOILHMJ_02830 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOOILHMJ_02831 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IOOILHMJ_02832 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IOOILHMJ_02833 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOOILHMJ_02834 9.8e-149 ytpQ S Belongs to the UPF0354 family
IOOILHMJ_02835 2.7e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IOOILHMJ_02836 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
IOOILHMJ_02837 1.2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IOOILHMJ_02838 2.2e-51 ytzB S small secreted protein
IOOILHMJ_02839 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
IOOILHMJ_02840 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
IOOILHMJ_02841 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOOILHMJ_02842 2e-45 ytzH S YtzH-like protein
IOOILHMJ_02843 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
IOOILHMJ_02844 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
IOOILHMJ_02845 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IOOILHMJ_02846 2.9e-165 ytlQ
IOOILHMJ_02847 4.4e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IOOILHMJ_02848 3.3e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOOILHMJ_02849 2.1e-268 pepV 3.5.1.18 E Dipeptidase
IOOILHMJ_02850 7.2e-226 pbuO S permease
IOOILHMJ_02851 3.2e-201 ythQ U Bacterial ABC transporter protein EcsB
IOOILHMJ_02852 1.7e-128 ythP V ABC transporter
IOOILHMJ_02853 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
IOOILHMJ_02854 5.9e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOOILHMJ_02855 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOOILHMJ_02856 6.9e-231 ytfP S HI0933-like protein
IOOILHMJ_02857 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IOOILHMJ_02858 3.1e-26 yteV S Sporulation protein Cse60
IOOILHMJ_02859 1.2e-115 yteU S Integral membrane protein
IOOILHMJ_02860 3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
IOOILHMJ_02861 1.1e-71 yteS G transport
IOOILHMJ_02862 4.5e-221 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IOOILHMJ_02863 9.9e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
IOOILHMJ_02864 0.0 ytdP K Transcriptional regulator
IOOILHMJ_02865 1.4e-286 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
IOOILHMJ_02866 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
IOOILHMJ_02867 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
IOOILHMJ_02868 4.1e-220 bioI 1.14.14.46 C Cytochrome P450
IOOILHMJ_02869 7.1e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IOOILHMJ_02870 2.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IOOILHMJ_02871 7.4e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOOILHMJ_02872 3.9e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IOOILHMJ_02873 1.2e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IOOILHMJ_02874 5.4e-172 ytaP S Acetyl xylan esterase (AXE1)
IOOILHMJ_02875 2.8e-188 msmR K Transcriptional regulator
IOOILHMJ_02876 2e-244 msmE G Bacterial extracellular solute-binding protein
IOOILHMJ_02877 6.2e-168 amyD P ABC transporter
IOOILHMJ_02878 2.4e-142 amyC P ABC transporter (permease)
IOOILHMJ_02879 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IOOILHMJ_02880 2.1e-51 ytwF P Sulfurtransferase
IOOILHMJ_02881 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOOILHMJ_02882 7.7e-55 ytvB S Protein of unknown function (DUF4257)
IOOILHMJ_02883 4.7e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IOOILHMJ_02884 1.1e-209 yttB EGP Major facilitator Superfamily
IOOILHMJ_02885 2.5e-42 yttA 2.7.13.3 S Pfam Transposase IS66
IOOILHMJ_02886 0.0 bceB V ABC transporter (permease)
IOOILHMJ_02887 1.1e-138 bceA V ABC transporter, ATP-binding protein
IOOILHMJ_02888 4e-184 T PhoQ Sensor
IOOILHMJ_02889 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_02890 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
IOOILHMJ_02891 3.1e-127 ytrE V ABC transporter, ATP-binding protein
IOOILHMJ_02892 1.4e-149
IOOILHMJ_02893 2e-164 P ABC-2 family transporter protein
IOOILHMJ_02894 1.1e-161 ytrB P abc transporter atp-binding protein
IOOILHMJ_02895 5.1e-66 ytrA K GntR family transcriptional regulator
IOOILHMJ_02897 6.7e-41 ytzC S Protein of unknown function (DUF2524)
IOOILHMJ_02898 3.1e-189 yhcC S Fe-S oxidoreductase
IOOILHMJ_02899 9.7e-106 ytqB J Putative rRNA methylase
IOOILHMJ_02900 4.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
IOOILHMJ_02901 4.2e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
IOOILHMJ_02902 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IOOILHMJ_02903 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
IOOILHMJ_02904 0.0 asnB 6.3.5.4 E Asparagine synthase
IOOILHMJ_02905 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOOILHMJ_02906 2e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IOOILHMJ_02907 1.2e-38 ytmB S Protein of unknown function (DUF2584)
IOOILHMJ_02908 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IOOILHMJ_02909 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IOOILHMJ_02910 1.4e-144 ytlC P ABC transporter
IOOILHMJ_02911 5.2e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IOOILHMJ_02912 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
IOOILHMJ_02913 1.7e-61 ytkC S Bacteriophage holin family
IOOILHMJ_02914 2.1e-76 dps P Belongs to the Dps family
IOOILHMJ_02916 2e-71 ytkA S YtkA-like
IOOILHMJ_02917 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOOILHMJ_02918 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IOOILHMJ_02919 7.9e-41 rpmE2 J Ribosomal protein L31
IOOILHMJ_02920 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
IOOILHMJ_02921 1.2e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IOOILHMJ_02922 1.1e-24 S Domain of Unknown Function (DUF1540)
IOOILHMJ_02923 3.1e-148 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IOOILHMJ_02924 3e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IOOILHMJ_02925 1.4e-136 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IOOILHMJ_02926 3.3e-169 troA P Belongs to the bacterial solute-binding protein 9 family
IOOILHMJ_02927 3e-212 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IOOILHMJ_02928 8.8e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IOOILHMJ_02929 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IOOILHMJ_02930 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IOOILHMJ_02931 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IOOILHMJ_02932 3.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
IOOILHMJ_02933 2.6e-132 dksA T COG1734 DnaK suppressor protein
IOOILHMJ_02934 2.8e-151 galU 2.7.7.9 M Nucleotidyl transferase
IOOILHMJ_02935 3.2e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOOILHMJ_02936 1.8e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
IOOILHMJ_02937 5.7e-233 ytcC M Glycosyltransferase Family 4
IOOILHMJ_02939 3.1e-203 cotS S Seems to be required for the assembly of the CotSA protein in spores
IOOILHMJ_02940 2e-216 cotSA M Glycosyl transferases group 1
IOOILHMJ_02941 3.7e-204 cotI S Spore coat protein
IOOILHMJ_02942 9.9e-77 tspO T membrane
IOOILHMJ_02943 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOOILHMJ_02944 1.3e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
IOOILHMJ_02945 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
IOOILHMJ_02946 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOOILHMJ_02947 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOOILHMJ_02956 7.8e-08
IOOILHMJ_02957 1.3e-09
IOOILHMJ_02964 2e-08
IOOILHMJ_02969 3.4e-39 S COG NOG14552 non supervised orthologous group
IOOILHMJ_02970 5.7e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
IOOILHMJ_02971 9.3e-26 M1-753 M FR47-like protein
IOOILHMJ_02972 7.9e-48 M1-753 M FR47-like protein
IOOILHMJ_02973 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
IOOILHMJ_02974 1.6e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
IOOILHMJ_02975 3.9e-84 yuaE S DinB superfamily
IOOILHMJ_02976 3.3e-106 yuaD
IOOILHMJ_02977 5.4e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
IOOILHMJ_02978 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
IOOILHMJ_02979 1.3e-93 yuaC K Belongs to the GbsR family
IOOILHMJ_02980 2.2e-91 yuaB
IOOILHMJ_02981 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
IOOILHMJ_02982 7.9e-236 ktrB P Potassium
IOOILHMJ_02983 1e-38 yiaA S yiaA/B two helix domain
IOOILHMJ_02984 5.3e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOOILHMJ_02985 2.3e-271 yubD P Major Facilitator Superfamily
IOOILHMJ_02986 2.4e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
IOOILHMJ_02988 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOOILHMJ_02989 1.1e-188 yubA S transporter activity
IOOILHMJ_02990 1.6e-180 ygjR S Oxidoreductase
IOOILHMJ_02991 1.1e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
IOOILHMJ_02992 2.7e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
IOOILHMJ_02993 9.1e-270 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IOOILHMJ_02994 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
IOOILHMJ_02995 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
IOOILHMJ_02996 5.1e-239 mcpA NT chemotaxis protein
IOOILHMJ_02997 1.2e-293 mcpA NT chemotaxis protein
IOOILHMJ_02998 4.6e-200 mcpA NT chemotaxis protein
IOOILHMJ_02999 3e-223 mcpA NT chemotaxis protein
IOOILHMJ_03000 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
IOOILHMJ_03001 3.9e-35
IOOILHMJ_03002 2.1e-72 yugU S Uncharacterised protein family UPF0047
IOOILHMJ_03003 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
IOOILHMJ_03004 9.3e-234 yugS S COG1253 Hemolysins and related proteins containing CBS domains
IOOILHMJ_03005 1.4e-116 yugP S Zn-dependent protease
IOOILHMJ_03006 2.3e-38
IOOILHMJ_03007 1.2e-52 mstX S Membrane-integrating protein Mistic
IOOILHMJ_03008 1.1e-181 yugO P COG1226 Kef-type K transport systems
IOOILHMJ_03009 6.3e-72 yugN S YugN-like family
IOOILHMJ_03011 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
IOOILHMJ_03012 2.4e-228 yugK C Dehydrogenase
IOOILHMJ_03013 7.6e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
IOOILHMJ_03014 1.1e-34 yuzA S Domain of unknown function (DUF378)
IOOILHMJ_03015 2e-62 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
IOOILHMJ_03016 2.1e-199 yugH 2.6.1.1 E Aminotransferase
IOOILHMJ_03017 1.6e-85 alaR K Transcriptional regulator
IOOILHMJ_03018 1.3e-156 yugF I Hydrolase
IOOILHMJ_03019 4.6e-39 yugE S Domain of unknown function (DUF1871)
IOOILHMJ_03020 9.9e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IOOILHMJ_03021 3.9e-232 T PhoQ Sensor
IOOILHMJ_03022 3.3e-70 kapB G Kinase associated protein B
IOOILHMJ_03023 1.2e-114 kapD L the KinA pathway to sporulation
IOOILHMJ_03025 1.6e-183 yuxJ EGP Major facilitator Superfamily
IOOILHMJ_03026 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
IOOILHMJ_03027 1.8e-74 yuxK S protein conserved in bacteria
IOOILHMJ_03028 6.3e-78 yufK S Family of unknown function (DUF5366)
IOOILHMJ_03029 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IOOILHMJ_03030 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
IOOILHMJ_03031 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IOOILHMJ_03032 1.2e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IOOILHMJ_03033 6e-183 yufP S Belongs to the binding-protein-dependent transport system permease family
IOOILHMJ_03034 1.5e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
IOOILHMJ_03035 8.2e-233 maeN C COG3493 Na citrate symporter
IOOILHMJ_03036 5e-15
IOOILHMJ_03037 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IOOILHMJ_03038 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOOILHMJ_03039 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOOILHMJ_03040 7.9e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOOILHMJ_03041 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOOILHMJ_03042 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOOILHMJ_03043 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
IOOILHMJ_03044 3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
IOOILHMJ_03045 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOOILHMJ_03046 1.4e-253 comP 2.7.13.3 T Histidine kinase
IOOILHMJ_03048 8.5e-128 comQ H Belongs to the FPP GGPP synthase family
IOOILHMJ_03050 8.5e-23 yuzC
IOOILHMJ_03051 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
IOOILHMJ_03052 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOOILHMJ_03053 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
IOOILHMJ_03054 8.7e-66 yueI S Protein of unknown function (DUF1694)
IOOILHMJ_03055 7.4e-39 yueH S YueH-like protein
IOOILHMJ_03056 6.6e-31 yueG S Spore germination protein gerPA/gerPF
IOOILHMJ_03057 5.4e-190 yueF S transporter activity
IOOILHMJ_03058 1.6e-64 S Protein of unknown function (DUF2283)
IOOILHMJ_03059 2.9e-24 S Protein of unknown function (DUF2642)
IOOILHMJ_03060 4.8e-96 yueE S phosphohydrolase
IOOILHMJ_03061 1.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_03062 6.6e-65 yueC S Family of unknown function (DUF5383)
IOOILHMJ_03063 0.0 esaA S type VII secretion protein EsaA
IOOILHMJ_03064 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOOILHMJ_03065 3.4e-210 essB S WXG100 protein secretion system (Wss), protein YukC
IOOILHMJ_03066 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
IOOILHMJ_03067 2.8e-45 esxA S Belongs to the WXG100 family
IOOILHMJ_03068 7.2e-228 yukF QT Transcriptional regulator
IOOILHMJ_03069 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
IOOILHMJ_03070 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
IOOILHMJ_03071 1.1e-35 mbtH S MbtH-like protein
IOOILHMJ_03072 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_03073 4.2e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
IOOILHMJ_03074 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
IOOILHMJ_03075 9.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
IOOILHMJ_03076 3.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_03077 3.7e-165 besA S Putative esterase
IOOILHMJ_03078 1.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
IOOILHMJ_03079 2.8e-92 bioY S Biotin biosynthesis protein
IOOILHMJ_03080 3.9e-211 yuiF S antiporter
IOOILHMJ_03081 1.7e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IOOILHMJ_03082 1.2e-77 yuiD S protein conserved in bacteria
IOOILHMJ_03083 4.7e-117 yuiC S protein conserved in bacteria
IOOILHMJ_03084 5.1e-24 yuiB S Putative membrane protein
IOOILHMJ_03085 1.2e-235 yumB 1.6.99.3 C NADH dehydrogenase
IOOILHMJ_03086 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
IOOILHMJ_03088 3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOOILHMJ_03089 2.2e-116 paiB K Putative FMN-binding domain
IOOILHMJ_03090 3e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOOILHMJ_03091 3.7e-63 erpA S Belongs to the HesB IscA family
IOOILHMJ_03092 2.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOOILHMJ_03093 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOOILHMJ_03094 3.2e-39 yuzB S Belongs to the UPF0349 family
IOOILHMJ_03095 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
IOOILHMJ_03096 2.5e-55 yuzD S protein conserved in bacteria
IOOILHMJ_03097 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
IOOILHMJ_03098 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
IOOILHMJ_03099 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOOILHMJ_03100 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IOOILHMJ_03101 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
IOOILHMJ_03102 1.1e-197 yutH S Spore coat protein
IOOILHMJ_03103 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IOOILHMJ_03104 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOOILHMJ_03105 4.3e-74 yutE S Protein of unknown function DUF86
IOOILHMJ_03106 9.7e-48 yutD S protein conserved in bacteria
IOOILHMJ_03107 1.4e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOOILHMJ_03108 2.3e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IOOILHMJ_03109 4.9e-195 lytH M Peptidase, M23
IOOILHMJ_03110 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
IOOILHMJ_03111 9.1e-47 yunC S Domain of unknown function (DUF1805)
IOOILHMJ_03112 1.7e-262 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IOOILHMJ_03113 2.6e-141 yunE S membrane transporter protein
IOOILHMJ_03114 4.3e-171 yunF S Protein of unknown function DUF72
IOOILHMJ_03115 7.6e-58 yunG
IOOILHMJ_03116 6.6e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IOOILHMJ_03117 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
IOOILHMJ_03118 4.1e-232 pbuX F Permease family
IOOILHMJ_03119 1.6e-222 pbuX F xanthine
IOOILHMJ_03120 1.2e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IOOILHMJ_03121 3.2e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IOOILHMJ_03123 2e-94 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IOOILHMJ_03124 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IOOILHMJ_03125 1.5e-144 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IOOILHMJ_03126 8.4e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
IOOILHMJ_03127 1.8e-181 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IOOILHMJ_03129 4.3e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IOOILHMJ_03130 1.6e-230 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IOOILHMJ_03131 1.3e-167 bsn L Ribonuclease
IOOILHMJ_03132 3.8e-204 msmX P Belongs to the ABC transporter superfamily
IOOILHMJ_03133 3.3e-135 yurK K UTRA
IOOILHMJ_03134 9.7e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
IOOILHMJ_03135 1.8e-167 yurM P COG0395 ABC-type sugar transport system, permease component
IOOILHMJ_03136 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
IOOILHMJ_03137 2e-236 yurO G COG1653 ABC-type sugar transport system, periplasmic component
IOOILHMJ_03138 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IOOILHMJ_03139 5.9e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
IOOILHMJ_03140 4.6e-205 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
IOOILHMJ_03142 1e-41
IOOILHMJ_03143 1.9e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOOILHMJ_03144 3.5e-271 sufB O FeS cluster assembly
IOOILHMJ_03145 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
IOOILHMJ_03146 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOOILHMJ_03147 1.8e-245 sufD O assembly protein SufD
IOOILHMJ_03148 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IOOILHMJ_03149 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IOOILHMJ_03150 1.6e-146 metQ P Belongs to the NlpA lipoprotein family
IOOILHMJ_03151 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
IOOILHMJ_03152 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOOILHMJ_03153 2.4e-56 yusD S SCP-2 sterol transfer family
IOOILHMJ_03154 5.6e-55 traF CO Thioredoxin
IOOILHMJ_03155 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
IOOILHMJ_03156 1.1e-39 yusG S Protein of unknown function (DUF2553)
IOOILHMJ_03157 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IOOILHMJ_03158 8.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
IOOILHMJ_03159 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
IOOILHMJ_03160 7.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
IOOILHMJ_03161 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
IOOILHMJ_03162 8.1e-09 S YuzL-like protein
IOOILHMJ_03163 4.2e-164 fadM E Proline dehydrogenase
IOOILHMJ_03164 5.1e-40
IOOILHMJ_03165 5.4e-53 yusN M Coat F domain
IOOILHMJ_03166 1.5e-72 yusO K Iron dependent repressor, N-terminal DNA binding domain
IOOILHMJ_03167 8.5e-293 yusP P Major facilitator superfamily
IOOILHMJ_03168 2.1e-64 yusQ S Tautomerase enzyme
IOOILHMJ_03169 1.2e-105 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_03170 2e-155 yusT K LysR substrate binding domain
IOOILHMJ_03171 3.8e-47 yusU S Protein of unknown function (DUF2573)
IOOILHMJ_03172 1e-153 yusV 3.6.3.34 HP ABC transporter
IOOILHMJ_03173 1.6e-65 S YusW-like protein
IOOILHMJ_03174 3.9e-299 pepF2 E COG1164 Oligoendopeptidase F
IOOILHMJ_03175 3.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_03176 2.7e-79 dps P Ferritin-like domain
IOOILHMJ_03177 8.9e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOOILHMJ_03178 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_03179 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
IOOILHMJ_03180 4.3e-158 yuxN K Transcriptional regulator
IOOILHMJ_03181 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOOILHMJ_03182 3.9e-24 S Protein of unknown function (DUF3970)
IOOILHMJ_03183 2e-245 gerAA EG Spore germination protein
IOOILHMJ_03184 1.1e-195 gerAB E Spore germination protein
IOOILHMJ_03185 7.2e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
IOOILHMJ_03186 3.9e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOOILHMJ_03187 5.5e-187 vraS 2.7.13.3 T Histidine kinase
IOOILHMJ_03188 2.1e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IOOILHMJ_03189 3.7e-125 liaG S Putative adhesin
IOOILHMJ_03190 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IOOILHMJ_03191 5.6e-62 liaI S membrane
IOOILHMJ_03192 4.8e-227 yvqJ EGP Major facilitator Superfamily
IOOILHMJ_03193 1.4e-99 yvqK 2.5.1.17 S Adenosyltransferase
IOOILHMJ_03194 9.5e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IOOILHMJ_03195 2.9e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_03196 3.8e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IOOILHMJ_03197 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_03198 6.4e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
IOOILHMJ_03199 0.0 T PhoQ Sensor
IOOILHMJ_03200 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_03201 3.6e-22
IOOILHMJ_03202 2.8e-97 yvrI K RNA polymerase
IOOILHMJ_03203 2.4e-19 S YvrJ protein family
IOOILHMJ_03204 1.8e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
IOOILHMJ_03205 1.3e-64 yvrL S Regulatory protein YrvL
IOOILHMJ_03206 2.6e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
IOOILHMJ_03207 1.6e-123 macB V ABC transporter, ATP-binding protein
IOOILHMJ_03208 3.4e-174 M Efflux transporter rnd family, mfp subunit
IOOILHMJ_03209 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
IOOILHMJ_03210 1.3e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_03211 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOOILHMJ_03212 3.4e-177 fhuD P ABC transporter
IOOILHMJ_03213 7e-235 yvsH E Arginine ornithine antiporter
IOOILHMJ_03214 6.5e-16 S Small spore protein J (Spore_SspJ)
IOOILHMJ_03215 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
IOOILHMJ_03216 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IOOILHMJ_03217 1.9e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
IOOILHMJ_03218 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
IOOILHMJ_03219 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
IOOILHMJ_03220 1.1e-155 yvgN S reductase
IOOILHMJ_03221 5.4e-86 yvgO
IOOILHMJ_03222 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
IOOILHMJ_03223 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IOOILHMJ_03224 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IOOILHMJ_03225 0.0 helD 3.6.4.12 L DNA helicase
IOOILHMJ_03227 1.6e-106 yvgT S membrane
IOOILHMJ_03228 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
IOOILHMJ_03229 1.6e-104 bdbD O Thioredoxin
IOOILHMJ_03230 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IOOILHMJ_03231 0.0 copA 3.6.3.54 P P-type ATPase
IOOILHMJ_03232 1.5e-29 copZ P Copper resistance protein CopZ
IOOILHMJ_03233 8.2e-48 csoR S transcriptional
IOOILHMJ_03234 3.8e-196 yvaA 1.1.1.371 S Oxidoreductase
IOOILHMJ_03235 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOOILHMJ_03236 0.0 yvaC S Fusaric acid resistance protein-like
IOOILHMJ_03237 5.7e-73 yvaD S Family of unknown function (DUF5360)
IOOILHMJ_03238 1.8e-54 yvaE P Small Multidrug Resistance protein
IOOILHMJ_03239 1.6e-97 K Bacterial regulatory proteins, tetR family
IOOILHMJ_03240 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_03242 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IOOILHMJ_03243 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOOILHMJ_03244 5.6e-143 est 3.1.1.1 S Carboxylesterase
IOOILHMJ_03245 2.4e-23 secG U Preprotein translocase subunit SecG
IOOILHMJ_03246 2e-151 yvaM S Serine aminopeptidase, S33
IOOILHMJ_03247 7.5e-36 yvzC K Transcriptional
IOOILHMJ_03248 4e-69 K transcriptional
IOOILHMJ_03249 8.3e-67 yvaO K Cro/C1-type HTH DNA-binding domain
IOOILHMJ_03250 5.3e-53 yodB K transcriptional
IOOILHMJ_03252 1.4e-21 S Protein of unknown function (DUF2283)
IOOILHMJ_03253 1.9e-15 M COG3209 Rhs family protein
IOOILHMJ_03254 2e-42 aprE 3.4.21.62 O Belongs to the peptidase S8 family
IOOILHMJ_03255 2.5e-99 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IOOILHMJ_03256 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOOILHMJ_03257 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IOOILHMJ_03258 9.8e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IOOILHMJ_03259 3.3e-60 yvbF K Belongs to the GbsR family
IOOILHMJ_03260 5.6e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IOOILHMJ_03261 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOOILHMJ_03262 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IOOILHMJ_03263 9.8e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IOOILHMJ_03264 3.5e-97 yvbF K Belongs to the GbsR family
IOOILHMJ_03265 2.1e-101 yvbG U UPF0056 membrane protein
IOOILHMJ_03266 4.3e-112 yvbH S YvbH-like oligomerisation region
IOOILHMJ_03267 3.7e-120 exoY M Membrane
IOOILHMJ_03268 0.0 tcaA S response to antibiotic
IOOILHMJ_03269 1.5e-80 yvbK 3.1.3.25 K acetyltransferase
IOOILHMJ_03270 9.3e-175 EGP Major facilitator Superfamily
IOOILHMJ_03271 3.7e-152
IOOILHMJ_03272 2.3e-114 S GlcNAc-PI de-N-acetylase
IOOILHMJ_03273 1.9e-122 C WbqC-like protein family
IOOILHMJ_03274 2.2e-113 M Protein involved in cellulose biosynthesis
IOOILHMJ_03275 2.3e-157 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IOOILHMJ_03276 2.1e-147 5.1.3.2 M GDP-mannose 4,6 dehydratase
IOOILHMJ_03277 3.1e-185 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IOOILHMJ_03278 1.3e-217 1.1.1.136 M UDP binding domain
IOOILHMJ_03279 1.2e-164 ywaD 3.4.11.10, 3.4.11.6 S PA domain
IOOILHMJ_03280 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOOILHMJ_03281 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
IOOILHMJ_03282 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOOILHMJ_03283 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IOOILHMJ_03284 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOOILHMJ_03285 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IOOILHMJ_03286 1.6e-252 araE EGP Major facilitator Superfamily
IOOILHMJ_03287 1.2e-202 araR K transcriptional
IOOILHMJ_03288 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOOILHMJ_03289 5.6e-158 yvbU K Transcriptional regulator
IOOILHMJ_03290 2.7e-155 yvbV EG EamA-like transporter family
IOOILHMJ_03291 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
IOOILHMJ_03292 8.3e-193 yvbX S Glycosyl hydrolase
IOOILHMJ_03293 2.8e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IOOILHMJ_03294 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IOOILHMJ_03295 5.5e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IOOILHMJ_03296 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOOILHMJ_03297 7.1e-198 desK 2.7.13.3 T Histidine kinase
IOOILHMJ_03298 3.4e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
IOOILHMJ_03299 1.2e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
IOOILHMJ_03300 9.8e-157 rsbQ S Alpha/beta hydrolase family
IOOILHMJ_03301 2.1e-195 rsbU 3.1.3.3 T response regulator
IOOILHMJ_03302 2.1e-249 galA 3.2.1.89 G arabinogalactan
IOOILHMJ_03303 0.0 lacA 3.2.1.23 G beta-galactosidase
IOOILHMJ_03304 1.6e-149 ganQ P transport
IOOILHMJ_03305 8.4e-232 malC P COG1175 ABC-type sugar transport systems, permease components
IOOILHMJ_03306 1.8e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
IOOILHMJ_03307 6.8e-184 lacR K Transcriptional regulator
IOOILHMJ_03308 1e-112 yvfI K COG2186 Transcriptional regulators
IOOILHMJ_03309 9.7e-308 yvfH C L-lactate permease
IOOILHMJ_03310 6.7e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IOOILHMJ_03311 1e-31 yvfG S YvfG protein
IOOILHMJ_03312 1.7e-184 yvfF GM Exopolysaccharide biosynthesis protein
IOOILHMJ_03313 8.4e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IOOILHMJ_03314 7.6e-51 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
IOOILHMJ_03315 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IOOILHMJ_03316 4.5e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOOILHMJ_03317 1.6e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
IOOILHMJ_03318 9.2e-203 epsI GM pyruvyl transferase
IOOILHMJ_03319 2.2e-193 epsH GT2 S Glycosyltransferase like family 2
IOOILHMJ_03320 7e-206 epsG S EpsG family
IOOILHMJ_03321 4.2e-217 epsF GT4 M Glycosyl transferases group 1
IOOILHMJ_03322 1e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IOOILHMJ_03323 5.2e-220 epsD GT4 M Glycosyl transferase 4-like
IOOILHMJ_03324 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
IOOILHMJ_03325 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
IOOILHMJ_03326 4e-122 ywqC M biosynthesis protein
IOOILHMJ_03327 2.4e-75 slr K transcriptional
IOOILHMJ_03328 5.9e-277 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
IOOILHMJ_03330 5.1e-92 padC Q Phenolic acid decarboxylase
IOOILHMJ_03331 4.5e-74 MA20_18690 S Protein of unknown function (DUF3237)
IOOILHMJ_03332 2.5e-121 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IOOILHMJ_03333 5.5e-253 pbpE V Beta-lactamase
IOOILHMJ_03334 8.4e-70
IOOILHMJ_03335 1.7e-273 sacB 2.4.1.10 GH68 M levansucrase activity
IOOILHMJ_03336 8.6e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
IOOILHMJ_03337 3.9e-295 yveA E amino acid
IOOILHMJ_03338 2.2e-105 yvdT K Transcriptional regulator
IOOILHMJ_03339 4.3e-50 ykkC P Small Multidrug Resistance protein
IOOILHMJ_03340 7.1e-50 sugE P Small Multidrug Resistance protein
IOOILHMJ_03341 1.8e-92 yvdQ S Protein of unknown function (DUF3231)
IOOILHMJ_03342 2.4e-78 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
IOOILHMJ_03343 3.4e-93 sdpB S Vitamin K-dependent gamma-carboxylase
IOOILHMJ_03344 3.4e-38
IOOILHMJ_03348 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOOILHMJ_03349 1.6e-112 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
IOOILHMJ_03350 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
IOOILHMJ_03351 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
IOOILHMJ_03352 3.1e-156 malA S Protein of unknown function (DUF1189)
IOOILHMJ_03353 5.6e-147 malD P transport
IOOILHMJ_03354 1e-243 malC P COG1175 ABC-type sugar transport systems, permease components
IOOILHMJ_03355 1.2e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
IOOILHMJ_03356 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
IOOILHMJ_03357 1.8e-173 yvdE K Transcriptional regulator
IOOILHMJ_03358 1.2e-105 yvdD 3.2.2.10 S Belongs to the LOG family
IOOILHMJ_03359 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
IOOILHMJ_03360 3.4e-286 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
IOOILHMJ_03361 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IOOILHMJ_03362 1.4e-181 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOOILHMJ_03363 0.0 yxdM V ABC transporter (permease)
IOOILHMJ_03364 5.6e-141 yvcR V ABC transporter, ATP-binding protein
IOOILHMJ_03365 2.9e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
IOOILHMJ_03366 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_03367 1.8e-33
IOOILHMJ_03368 1.1e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
IOOILHMJ_03369 1.6e-36 crh G Phosphocarrier protein Chr
IOOILHMJ_03370 1.4e-170 whiA K May be required for sporulation
IOOILHMJ_03371 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IOOILHMJ_03372 5.7e-166 rapZ S Displays ATPase and GTPase activities
IOOILHMJ_03373 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IOOILHMJ_03374 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOOILHMJ_03375 2.1e-98 usp CBM50 M protein conserved in bacteria
IOOILHMJ_03376 1.9e-275 S COG0457 FOG TPR repeat
IOOILHMJ_03377 0.0 msbA2 3.6.3.44 V ABC transporter
IOOILHMJ_03379 1.8e-207
IOOILHMJ_03380 2.2e-78
IOOILHMJ_03381 1.7e-108 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
IOOILHMJ_03382 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOOILHMJ_03383 3.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IOOILHMJ_03384 9.9e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOOILHMJ_03385 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IOOILHMJ_03386 4.9e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOOILHMJ_03387 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IOOILHMJ_03388 8.2e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IOOILHMJ_03389 1e-139 yvpB NU protein conserved in bacteria
IOOILHMJ_03390 1.6e-120 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
IOOILHMJ_03391 1.1e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
IOOILHMJ_03392 2.1e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IOOILHMJ_03393 2.4e-159 yvoD P COG0370 Fe2 transport system protein B
IOOILHMJ_03394 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOOILHMJ_03395 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOOILHMJ_03396 1.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOOILHMJ_03397 2.7e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOOILHMJ_03398 1.2e-132 yvoA K transcriptional
IOOILHMJ_03399 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
IOOILHMJ_03400 8.4e-50 yvlD S Membrane
IOOILHMJ_03401 4.4e-26 pspB KT PspC domain
IOOILHMJ_03402 2.4e-166 yvlB S Putative adhesin
IOOILHMJ_03403 8e-49 yvlA
IOOILHMJ_03404 5.7e-33 yvkN
IOOILHMJ_03405 8.5e-116 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IOOILHMJ_03406 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOOILHMJ_03407 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOOILHMJ_03408 1.2e-30 csbA S protein conserved in bacteria
IOOILHMJ_03409 0.0 yvkC 2.7.9.2 GT Phosphotransferase
IOOILHMJ_03410 7e-101 yvkB K Transcriptional regulator
IOOILHMJ_03411 1.1e-224 yvkA EGP Major facilitator Superfamily
IOOILHMJ_03412 4.1e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOOILHMJ_03413 5.3e-56 swrA S Swarming motility protein
IOOILHMJ_03414 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
IOOILHMJ_03415 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IOOILHMJ_03416 1.6e-123 ftsE D cell division ATP-binding protein FtsE
IOOILHMJ_03417 4.5e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
IOOILHMJ_03418 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
IOOILHMJ_03419 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOOILHMJ_03420 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOOILHMJ_03421 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOOILHMJ_03422 2.8e-66
IOOILHMJ_03423 1.9e-08 fliT S bacterial-type flagellum organization
IOOILHMJ_03424 6.5e-69 fliS N flagellar protein FliS
IOOILHMJ_03425 1.4e-241 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IOOILHMJ_03426 6.1e-57 flaG N flagellar protein FlaG
IOOILHMJ_03427 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IOOILHMJ_03428 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IOOILHMJ_03429 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IOOILHMJ_03430 5.7e-50 yviE
IOOILHMJ_03431 1.3e-154 flgL N Belongs to the bacterial flagellin family
IOOILHMJ_03432 1.1e-262 flgK N flagellar hook-associated protein
IOOILHMJ_03433 4.1e-78 flgN NOU FlgN protein
IOOILHMJ_03434 8e-39 flgM KNU Negative regulator of flagellin synthesis
IOOILHMJ_03435 7e-74 yvyF S flagellar protein
IOOILHMJ_03436 1.2e-124 comFC S Phosphoribosyl transferase domain
IOOILHMJ_03437 3.7e-45 comFB S Late competence development protein ComFB
IOOILHMJ_03438 1.3e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IOOILHMJ_03439 2.1e-154 degV S protein conserved in bacteria
IOOILHMJ_03440 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOOILHMJ_03441 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IOOILHMJ_03442 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
IOOILHMJ_03443 6e-163 yvhJ K Transcriptional regulator
IOOILHMJ_03444 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IOOILHMJ_03445 6.2e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
IOOILHMJ_03446 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
IOOILHMJ_03447 1.1e-113 tuaF M protein involved in exopolysaccharide biosynthesis
IOOILHMJ_03448 3.5e-261 tuaE M Teichuronic acid biosynthesis protein
IOOILHMJ_03449 2.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOOILHMJ_03450 2.9e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
IOOILHMJ_03451 7.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOOILHMJ_03452 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IOOILHMJ_03453 4.3e-94 M Glycosyltransferase like family 2
IOOILHMJ_03454 2e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IOOILHMJ_03455 0.0 lytB 3.5.1.28 D Stage II sporulation protein
IOOILHMJ_03456 1e-11
IOOILHMJ_03457 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IOOILHMJ_03458 1.5e-214 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOOILHMJ_03459 1e-87 M Glycosyltransferase like family 2
IOOILHMJ_03460 9.3e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IOOILHMJ_03461 1.8e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IOOILHMJ_03462 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOOILHMJ_03463 9.8e-270 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IOOILHMJ_03464 1e-132 tagG GM Transport permease protein
IOOILHMJ_03465 6.7e-149 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOOILHMJ_03466 2.7e-131 M Glycosyltransferase like family 2
IOOILHMJ_03467 2.5e-87
IOOILHMJ_03468 1.4e-110 ggaA M Glycosyltransferase like family 2
IOOILHMJ_03469 9.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOOILHMJ_03470 7.3e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
IOOILHMJ_03471 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOOILHMJ_03472 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOOILHMJ_03473 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IOOILHMJ_03474 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IOOILHMJ_03475 3.3e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOOILHMJ_03476 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOOILHMJ_03477 8.3e-213 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOOILHMJ_03478 8.7e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
IOOILHMJ_03479 2e-261 gerBA EG Spore germination protein
IOOILHMJ_03480 8.9e-193 gerBB E Spore germination protein
IOOILHMJ_03481 1.9e-206 gerAC S Spore germination protein
IOOILHMJ_03482 1.6e-247 ywtG EGP Major facilitator Superfamily
IOOILHMJ_03483 7e-141 ywtF K Transcriptional regulator
IOOILHMJ_03484 3.5e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
IOOILHMJ_03485 8.5e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IOOILHMJ_03486 3.6e-21 ywtC
IOOILHMJ_03487 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IOOILHMJ_03488 8.6e-70 pgsC S biosynthesis protein
IOOILHMJ_03489 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
IOOILHMJ_03490 5.1e-176 rbsR K transcriptional
IOOILHMJ_03491 1.6e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOOILHMJ_03492 2e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOOILHMJ_03493 1.2e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IOOILHMJ_03494 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
IOOILHMJ_03495 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
IOOILHMJ_03496 4.3e-92 batE T Sh3 type 3 domain protein
IOOILHMJ_03497 1.8e-47 ywsA S Protein of unknown function (DUF3892)
IOOILHMJ_03498 4.1e-95 ywrO S NADPH-quinone reductase (modulator of drug activity B)
IOOILHMJ_03499 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IOOILHMJ_03500 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IOOILHMJ_03501 1.1e-169 alsR K LysR substrate binding domain
IOOILHMJ_03502 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IOOILHMJ_03503 3.1e-124 ywrJ
IOOILHMJ_03504 1.6e-125 cotB
IOOILHMJ_03505 8.1e-207 cotH M Spore Coat
IOOILHMJ_03506 1.2e-12
IOOILHMJ_03507 4e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IOOILHMJ_03508 1.3e-51 S Domain of unknown function (DUF4181)
IOOILHMJ_03509 6.5e-306 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IOOILHMJ_03510 8e-82 ywrC K Transcriptional regulator
IOOILHMJ_03511 7.8e-103 ywrB P Chromate transporter
IOOILHMJ_03512 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
IOOILHMJ_03513 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IOOILHMJ_03514 2.3e-25
IOOILHMJ_03515 2.8e-81 ywqJ S Pre-toxin TG
IOOILHMJ_03516 5.2e-17
IOOILHMJ_03517 4.7e-43
IOOILHMJ_03518 5.7e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
IOOILHMJ_03519 1.3e-38 ywqI S Family of unknown function (DUF5344)
IOOILHMJ_03520 4.1e-21 S Domain of unknown function (DUF5082)
IOOILHMJ_03521 1.5e-149 ywqG S Domain of unknown function (DUF1963)
IOOILHMJ_03522 9.8e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOOILHMJ_03523 1.8e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
IOOILHMJ_03524 7.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
IOOILHMJ_03525 5.9e-116 ywqC M biosynthesis protein
IOOILHMJ_03526 2.7e-17
IOOILHMJ_03527 3.3e-305 ywqB S SWIM zinc finger
IOOILHMJ_03528 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IOOILHMJ_03529 6.7e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
IOOILHMJ_03530 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
IOOILHMJ_03531 4.9e-57 ssbB L Single-stranded DNA-binding protein
IOOILHMJ_03532 1.3e-66 ywpG
IOOILHMJ_03533 9e-66 ywpF S YwpF-like protein
IOOILHMJ_03534 2.3e-84 srtA 3.4.22.70 M Sortase family
IOOILHMJ_03535 0.0 M1-568 M cell wall anchor domain
IOOILHMJ_03536 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
IOOILHMJ_03537 0.0 ywpD T PhoQ Sensor
IOOILHMJ_03538 1.9e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOOILHMJ_03539 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOOILHMJ_03540 1.2e-189 S aspartate phosphatase
IOOILHMJ_03541 2.9e-140 flhP N flagellar basal body
IOOILHMJ_03542 3.4e-125 flhO N flagellar basal body
IOOILHMJ_03543 3.5e-180 mbl D Rod shape-determining protein
IOOILHMJ_03544 3e-44 spoIIID K Stage III sporulation protein D
IOOILHMJ_03545 2.1e-70 ywoH K COG1846 Transcriptional regulators
IOOILHMJ_03546 2.7e-211 ywoG EGP Major facilitator Superfamily
IOOILHMJ_03547 5.9e-221 ywoF P Right handed beta helix region
IOOILHMJ_03548 1.2e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
IOOILHMJ_03549 5.4e-240 ywoD EGP Major facilitator superfamily
IOOILHMJ_03550 1.2e-103 phzA Q Isochorismatase family
IOOILHMJ_03551 5.7e-77
IOOILHMJ_03552 2.5e-225 amt P Ammonium transporter
IOOILHMJ_03553 1.6e-58 nrgB K Belongs to the P(II) protein family
IOOILHMJ_03554 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
IOOILHMJ_03555 1e-72 ywnJ S VanZ like family
IOOILHMJ_03556 2.2e-114 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
IOOILHMJ_03557 7.8e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
IOOILHMJ_03558 4.5e-14 ywnC S Family of unknown function (DUF5362)
IOOILHMJ_03559 7.3e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
IOOILHMJ_03560 2.2e-70 ywnF S Family of unknown function (DUF5392)
IOOILHMJ_03561 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOOILHMJ_03562 5.3e-144 mta K transcriptional
IOOILHMJ_03563 1.7e-58 ywnC S Family of unknown function (DUF5362)
IOOILHMJ_03564 4e-113 ywnB S NAD(P)H-binding
IOOILHMJ_03565 1.7e-64 ywnA K Transcriptional regulator
IOOILHMJ_03566 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IOOILHMJ_03567 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IOOILHMJ_03568 1.4e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IOOILHMJ_03569 2.7e-20 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IOOILHMJ_03570 3.8e-11 csbD K CsbD-like
IOOILHMJ_03571 1.9e-83 ywmF S Peptidase M50
IOOILHMJ_03572 2.5e-102 S response regulator aspartate phosphatase
IOOILHMJ_03573 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IOOILHMJ_03574 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IOOILHMJ_03576 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
IOOILHMJ_03577 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
IOOILHMJ_03578 1.3e-174 spoIID D Stage II sporulation protein D
IOOILHMJ_03579 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOOILHMJ_03580 8.2e-134 ywmB S TATA-box binding
IOOILHMJ_03581 1.1e-31 ywzB S membrane
IOOILHMJ_03582 1.4e-86 ywmA
IOOILHMJ_03583 6.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IOOILHMJ_03584 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOOILHMJ_03585 5.6e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOOILHMJ_03586 7.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOOILHMJ_03587 1.7e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOOILHMJ_03588 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOOILHMJ_03589 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOOILHMJ_03590 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
IOOILHMJ_03591 2.5e-62 atpI S ATP synthase
IOOILHMJ_03592 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOOILHMJ_03593 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOOILHMJ_03594 7.2e-95 ywlG S Belongs to the UPF0340 family
IOOILHMJ_03595 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
IOOILHMJ_03596 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOOILHMJ_03597 1.7e-91 mntP P Probably functions as a manganese efflux pump
IOOILHMJ_03598 1.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOOILHMJ_03599 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
IOOILHMJ_03600 6.1e-112 spoIIR S stage II sporulation protein R
IOOILHMJ_03601 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
IOOILHMJ_03603 5e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOOILHMJ_03604 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOOILHMJ_03605 2.4e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOOILHMJ_03606 7.1e-74 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IOOILHMJ_03607 8.6e-160 ywkB S Membrane transport protein
IOOILHMJ_03608 0.0 sfcA 1.1.1.38 C malic enzyme
IOOILHMJ_03609 7e-104 tdk 2.7.1.21 F thymidine kinase
IOOILHMJ_03610 1.1e-32 rpmE J Binds the 23S rRNA
IOOILHMJ_03611 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOOILHMJ_03612 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
IOOILHMJ_03613 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOOILHMJ_03614 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOOILHMJ_03615 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
IOOILHMJ_03616 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
IOOILHMJ_03617 2.3e-90 ywjG S Domain of unknown function (DUF2529)
IOOILHMJ_03618 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOOILHMJ_03619 2.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOOILHMJ_03620 1.7e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
IOOILHMJ_03621 0.0 fadF C COG0247 Fe-S oxidoreductase
IOOILHMJ_03622 8.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IOOILHMJ_03623 9.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IOOILHMJ_03624 2.7e-42 ywjC
IOOILHMJ_03625 9e-95 ywjB H RibD C-terminal domain
IOOILHMJ_03626 0.0 ywjA V ABC transporter
IOOILHMJ_03627 5.5e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOOILHMJ_03628 3.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
IOOILHMJ_03629 1.1e-93 narJ 1.7.5.1 C nitrate reductase
IOOILHMJ_03630 2.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
IOOILHMJ_03631 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOOILHMJ_03632 7e-86 arfM T cyclic nucleotide binding
IOOILHMJ_03633 1.1e-138 ywiC S YwiC-like protein
IOOILHMJ_03634 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
IOOILHMJ_03635 4.9e-213 narK P COG2223 Nitrate nitrite transporter
IOOILHMJ_03636 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IOOILHMJ_03637 4.7e-73 ywiB S protein conserved in bacteria
IOOILHMJ_03638 1e-07 S Bacteriocin subtilosin A
IOOILHMJ_03639 1.1e-269 C Fe-S oxidoreductases
IOOILHMJ_03641 1.3e-131 cbiO V ABC transporter
IOOILHMJ_03642 4e-232 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
IOOILHMJ_03643 1.2e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
IOOILHMJ_03644 2.7e-205 L Peptidase, M16
IOOILHMJ_03646 7.1e-224 ywhL CO amine dehydrogenase activity
IOOILHMJ_03647 1.4e-195 ywhK CO amine dehydrogenase activity
IOOILHMJ_03648 1.8e-79 S aspartate phosphatase
IOOILHMJ_03650 8.1e-10
IOOILHMJ_03651 2.9e-20
IOOILHMJ_03654 9.9e-59 V ATPases associated with a variety of cellular activities
IOOILHMJ_03656 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
IOOILHMJ_03657 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IOOILHMJ_03658 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IOOILHMJ_03659 5.2e-95 ywhD S YwhD family
IOOILHMJ_03660 5.1e-119 ywhC S Peptidase family M50
IOOILHMJ_03661 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
IOOILHMJ_03662 9.5e-71 ywhA K Transcriptional regulator
IOOILHMJ_03663 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOOILHMJ_03665 1e-233 mmr U Major Facilitator Superfamily
IOOILHMJ_03666 1.1e-78 yffB K Transcriptional regulator
IOOILHMJ_03667 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
IOOILHMJ_03668 1.3e-254 ywfO S COG1078 HD superfamily phosphohydrolases
IOOILHMJ_03669 3.1e-36 ywzC S Belongs to the UPF0741 family
IOOILHMJ_03670 6.6e-110 rsfA_1
IOOILHMJ_03671 6.3e-157 ywfM EG EamA-like transporter family
IOOILHMJ_03672 1.9e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IOOILHMJ_03673 1.1e-156 cysL K Transcriptional regulator
IOOILHMJ_03674 7.3e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
IOOILHMJ_03675 9.6e-146 ywfI C May function as heme-dependent peroxidase
IOOILHMJ_03676 1.3e-137 IQ Enoyl-(Acyl carrier protein) reductase
IOOILHMJ_03677 4.7e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
IOOILHMJ_03678 5.6e-209 bacE EGP Major facilitator Superfamily
IOOILHMJ_03679 1e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IOOILHMJ_03680 2.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOOILHMJ_03681 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IOOILHMJ_03682 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IOOILHMJ_03683 3e-205 ywfA EGP Major facilitator Superfamily
IOOILHMJ_03684 3.7e-249 lysP E amino acid
IOOILHMJ_03685 0.0 rocB E arginine degradation protein
IOOILHMJ_03686 4.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IOOILHMJ_03687 2e-242 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IOOILHMJ_03688 1.2e-77
IOOILHMJ_03689 6.7e-86 spsL 5.1.3.13 M Spore Coat
IOOILHMJ_03690 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOOILHMJ_03691 1.3e-179 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOOILHMJ_03692 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOOILHMJ_03693 3.1e-184 spsG M Spore Coat
IOOILHMJ_03694 4.5e-129 spsF M Spore Coat
IOOILHMJ_03695 7.1e-214 spsE 2.5.1.56 M acid synthase
IOOILHMJ_03696 4.9e-162 spsD 2.3.1.210 K Spore Coat
IOOILHMJ_03697 1.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
IOOILHMJ_03698 1.1e-264 spsB M Capsule polysaccharide biosynthesis protein
IOOILHMJ_03699 1.5e-143 spsA M Spore Coat
IOOILHMJ_03700 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IOOILHMJ_03701 4.3e-59 ywdK S small membrane protein
IOOILHMJ_03702 1.4e-237 ywdJ F Xanthine uracil
IOOILHMJ_03703 8.6e-48 ywdI S Family of unknown function (DUF5327)
IOOILHMJ_03704 2.3e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IOOILHMJ_03705 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOOILHMJ_03706 6.1e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
IOOILHMJ_03707 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOOILHMJ_03708 2e-28 ywdA
IOOILHMJ_03709 2.5e-288 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
IOOILHMJ_03710 9.6e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOOILHMJ_03711 1.9e-39 focA P Formate/nitrite transporter
IOOILHMJ_03712 7e-150 sacT K transcriptional antiterminator
IOOILHMJ_03714 0.0 vpr O Belongs to the peptidase S8 family
IOOILHMJ_03715 1.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOOILHMJ_03716 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
IOOILHMJ_03717 2.3e-202 rodA D Belongs to the SEDS family
IOOILHMJ_03718 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
IOOILHMJ_03719 1e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IOOILHMJ_03720 8.1e-111 qoxC 1.10.3.12 C quinol oxidase, subunit
IOOILHMJ_03721 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IOOILHMJ_03722 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IOOILHMJ_03723 1e-35 ywzA S membrane
IOOILHMJ_03724 2.5e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IOOILHMJ_03725 4.5e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOOILHMJ_03726 9.5e-60 gtcA S GtrA-like protein
IOOILHMJ_03727 3.8e-122 ywcC K transcriptional regulator
IOOILHMJ_03729 1.7e-48 ywcB S Protein of unknown function, DUF485
IOOILHMJ_03730 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOOILHMJ_03731 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IOOILHMJ_03732 1.4e-223 ywbN P Dyp-type peroxidase family protein
IOOILHMJ_03733 2.1e-184 ycdO P periplasmic lipoprotein involved in iron transport
IOOILHMJ_03734 6.1e-250 P COG0672 High-affinity Fe2 Pb2 permease
IOOILHMJ_03735 2e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOOILHMJ_03736 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOOILHMJ_03737 6.2e-152 ywbI K Transcriptional regulator
IOOILHMJ_03738 3.2e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IOOILHMJ_03739 2.3e-111 ywbG M effector of murein hydrolase
IOOILHMJ_03740 2.6e-206 ywbF EGP Major facilitator Superfamily
IOOILHMJ_03741 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
IOOILHMJ_03742 2.4e-220 ywbD 2.1.1.191 J Methyltransferase
IOOILHMJ_03743 2.2e-66 ywbC 4.4.1.5 E glyoxalase
IOOILHMJ_03744 4.3e-121 ywbB S Protein of unknown function (DUF2711)
IOOILHMJ_03745 3.9e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOOILHMJ_03746 1.4e-270 epr 3.4.21.62 O Belongs to the peptidase S8 family
IOOILHMJ_03747 1.5e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOOILHMJ_03748 4e-153 sacY K transcriptional antiterminator
IOOILHMJ_03749 1.1e-163 gspA M General stress
IOOILHMJ_03750 3e-125 ywaF S Integral membrane protein
IOOILHMJ_03751 5.2e-87 ywaE K Transcriptional regulator
IOOILHMJ_03752 4.6e-230 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOOILHMJ_03753 5.9e-247 ywaD 3.4.11.10, 3.4.11.6 S PA domain
IOOILHMJ_03754 4.3e-115 ywaC 2.7.6.5 S protein conserved in bacteria
IOOILHMJ_03755 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IOOILHMJ_03756 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
IOOILHMJ_03757 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_03758 1.2e-232 dltB M membrane protein involved in D-alanine export
IOOILHMJ_03759 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOOILHMJ_03760 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOOILHMJ_03761 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_03762 6.9e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IOOILHMJ_03763 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IOOILHMJ_03764 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
IOOILHMJ_03765 6.3e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOOILHMJ_03766 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
IOOILHMJ_03767 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
IOOILHMJ_03768 1.1e-19 yxzF
IOOILHMJ_03769 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IOOILHMJ_03770 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IOOILHMJ_03771 2.4e-212 yxlH EGP Major facilitator Superfamily
IOOILHMJ_03772 4e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOOILHMJ_03773 5.3e-164 yxlF V ABC transporter, ATP-binding protein
IOOILHMJ_03774 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
IOOILHMJ_03775 4e-30
IOOILHMJ_03776 5.1e-40 yxlC S Family of unknown function (DUF5345)
IOOILHMJ_03777 9e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
IOOILHMJ_03778 8.6e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
IOOILHMJ_03779 3.6e-154 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOOILHMJ_03780 0.0 cydD V ATP-binding protein
IOOILHMJ_03781 4.6e-305 cydD V ATP-binding
IOOILHMJ_03782 1.1e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
IOOILHMJ_03783 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
IOOILHMJ_03784 1.9e-229 cimH C COG3493 Na citrate symporter
IOOILHMJ_03785 1e-309 3.4.24.84 O Peptidase family M48
IOOILHMJ_03787 1.5e-155 yxkH G Polysaccharide deacetylase
IOOILHMJ_03788 5.9e-205 msmK P Belongs to the ABC transporter superfamily
IOOILHMJ_03789 5.9e-163 lrp QT PucR C-terminal helix-turn-helix domain
IOOILHMJ_03790 8.5e-268 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOOILHMJ_03791 1.6e-146 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOOILHMJ_03792 7.6e-137
IOOILHMJ_03793 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOOILHMJ_03794 6.7e-95 yxkA S Phosphatidylethanolamine-binding protein
IOOILHMJ_03795 1.4e-161 yxjO K LysR substrate binding domain
IOOILHMJ_03796 2.4e-78 S Protein of unknown function (DUF1453)
IOOILHMJ_03797 2.9e-176 yxjM T Signal transduction histidine kinase
IOOILHMJ_03798 4.9e-114 K helix_turn_helix, Lux Regulon
IOOILHMJ_03799 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOOILHMJ_03802 2.7e-85 yxjI S LURP-one-related
IOOILHMJ_03803 1.9e-219 yxjG 2.1.1.14 E Methionine synthase
IOOILHMJ_03804 2.2e-218 yxjG 2.1.1.14 E Methionine synthase
IOOILHMJ_03805 4.5e-135 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IOOILHMJ_03806 8.8e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IOOILHMJ_03807 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IOOILHMJ_03808 5.4e-251 yxjC EG COG2610 H gluconate symporter and related permeases
IOOILHMJ_03809 4.6e-157 rlmA 2.1.1.187 Q Methyltransferase domain
IOOILHMJ_03810 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOOILHMJ_03811 4.7e-104 T Domain of unknown function (DUF4163)
IOOILHMJ_03812 1.5e-46 yxiS
IOOILHMJ_03813 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
IOOILHMJ_03814 1.9e-223 citH C Citrate transporter
IOOILHMJ_03815 3.3e-143 exoK GH16 M licheninase activity
IOOILHMJ_03816 4.1e-150 licT K transcriptional antiterminator
IOOILHMJ_03817 2.6e-110
IOOILHMJ_03818 8.6e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
IOOILHMJ_03819 1.2e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IOOILHMJ_03820 3.6e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
IOOILHMJ_03823 0.0 wapA M COG3209 Rhs family protein
IOOILHMJ_03824 2.8e-163 yxxF EG EamA-like transporter family
IOOILHMJ_03825 1.1e-72 yxiE T Belongs to the universal stress protein A family
IOOILHMJ_03826 1.4e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOOILHMJ_03827 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IOOILHMJ_03828 4e-21
IOOILHMJ_03829 3.2e-41
IOOILHMJ_03831 5.8e-56
IOOILHMJ_03832 2.1e-25
IOOILHMJ_03833 7.6e-42
IOOILHMJ_03834 4.2e-24 S Uncharacterized protein conserved in bacteria (DUF2247)
IOOILHMJ_03835 1.8e-45
IOOILHMJ_03836 2.8e-217 S nuclease activity
IOOILHMJ_03837 1.4e-38 yxiC S Family of unknown function (DUF5344)
IOOILHMJ_03838 4.6e-21 S Domain of unknown function (DUF5082)
IOOILHMJ_03839 0.0 L HKD family nuclease
IOOILHMJ_03841 1.1e-58 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IOOILHMJ_03842 7.4e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IOOILHMJ_03843 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IOOILHMJ_03844 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
IOOILHMJ_03845 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IOOILHMJ_03846 5.3e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
IOOILHMJ_03847 1.3e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IOOILHMJ_03848 6.8e-251 lysP E amino acid
IOOILHMJ_03849 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
IOOILHMJ_03850 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOOILHMJ_03851 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOOILHMJ_03852 5.1e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IOOILHMJ_03853 2e-152 yxxB S Domain of Unknown Function (DUF1206)
IOOILHMJ_03854 9.5e-195 eutH E Ethanolamine utilisation protein, EutH
IOOILHMJ_03855 8.1e-249 yxeQ S MmgE/PrpD family
IOOILHMJ_03856 1e-212 yxeP 3.5.1.47 E hydrolase activity
IOOILHMJ_03857 9.1e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
IOOILHMJ_03858 7.8e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
IOOILHMJ_03859 2.1e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
IOOILHMJ_03860 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOOILHMJ_03861 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOOILHMJ_03862 2.7e-185 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IOOILHMJ_03863 3.4e-149 yidA S hydrolases of the HAD superfamily
IOOILHMJ_03866 2.5e-14 yxeE
IOOILHMJ_03867 5.6e-16 yxeD
IOOILHMJ_03868 8.5e-69
IOOILHMJ_03869 1.1e-175 fhuD P ABC transporter
IOOILHMJ_03870 1.5e-58 yxeA S Protein of unknown function (DUF1093)
IOOILHMJ_03871 0.0 yxdM V ABC transporter (permease)
IOOILHMJ_03872 2.6e-138 yxdL V ABC transporter, ATP-binding protein
IOOILHMJ_03873 4e-181 T PhoQ Sensor
IOOILHMJ_03874 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_03875 3.5e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IOOILHMJ_03876 5.6e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IOOILHMJ_03877 6.6e-167 iolH G Xylose isomerase-like TIM barrel
IOOILHMJ_03878 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IOOILHMJ_03879 3.3e-234 iolF EGP Major facilitator Superfamily
IOOILHMJ_03880 6.7e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IOOILHMJ_03881 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IOOILHMJ_03882 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IOOILHMJ_03883 7.8e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IOOILHMJ_03884 1.1e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOOILHMJ_03885 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
IOOILHMJ_03886 8.3e-176 iolS C Aldo keto reductase
IOOILHMJ_03888 8.3e-48 yxcD S Protein of unknown function (DUF2653)
IOOILHMJ_03889 7.3e-245 csbC EGP Major facilitator Superfamily
IOOILHMJ_03890 0.0 htpG O Molecular chaperone. Has ATPase activity
IOOILHMJ_03892 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
IOOILHMJ_03893 5e-207 yxbF K Bacterial regulatory proteins, tetR family
IOOILHMJ_03894 2.1e-244 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IOOILHMJ_03895 2.8e-31 yxaI S membrane protein domain
IOOILHMJ_03896 1.2e-76 S PQQ-like domain
IOOILHMJ_03897 1.3e-64 S Family of unknown function (DUF5391)
IOOILHMJ_03898 6.9e-75 yxaI S membrane protein domain
IOOILHMJ_03899 3e-226 P Protein of unknown function (DUF418)
IOOILHMJ_03900 1.6e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
IOOILHMJ_03901 6e-100 yxaF K Transcriptional regulator
IOOILHMJ_03902 2.8e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IOOILHMJ_03903 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
IOOILHMJ_03904 5.2e-50 S LrgA family
IOOILHMJ_03905 1.3e-117 yxaC M effector of murein hydrolase
IOOILHMJ_03906 1.1e-192 yxaB GM Polysaccharide pyruvyl transferase
IOOILHMJ_03907 3.6e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IOOILHMJ_03908 1.6e-126 gntR K transcriptional
IOOILHMJ_03909 3.9e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
IOOILHMJ_03910 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
IOOILHMJ_03911 9.3e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOOILHMJ_03912 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
IOOILHMJ_03913 3.8e-287 ahpF O Alkyl hydroperoxide reductase
IOOILHMJ_03914 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
IOOILHMJ_03915 1.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOOILHMJ_03916 5e-32 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IOOILHMJ_03917 5.6e-124 yydK K Transcriptional regulator
IOOILHMJ_03918 7.6e-13
IOOILHMJ_03919 1.4e-117 S ABC-2 family transporter protein
IOOILHMJ_03920 1.6e-109 prrC P ABC transporter
IOOILHMJ_03921 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
IOOILHMJ_03922 0.0 res 3.1.21.5 V Type III restriction enzyme, res subunit
IOOILHMJ_03923 4.7e-152 mod 2.1.1.72 L DNA methylase
IOOILHMJ_03924 1e-132 addA 3.6.4.12 L PD-(D/E)XK nuclease superfamily
IOOILHMJ_03925 0.0 3.6.4.12 L DNA helicase
IOOILHMJ_03926 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOOILHMJ_03927 1.1e-09 S YyzF-like protein
IOOILHMJ_03928 3.4e-65
IOOILHMJ_03929 8.1e-232 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IOOILHMJ_03931 2.2e-30 yycQ S Protein of unknown function (DUF2651)
IOOILHMJ_03932 3.5e-208 yycP
IOOILHMJ_03933 2.5e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IOOILHMJ_03934 2.9e-84 yycN 2.3.1.128 K Acetyltransferase
IOOILHMJ_03935 5e-188 S aspartate phosphatase
IOOILHMJ_03937 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
IOOILHMJ_03938 1e-254 rocE E amino acid
IOOILHMJ_03939 1.9e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
IOOILHMJ_03940 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IOOILHMJ_03941 3.2e-220 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOOILHMJ_03942 7.4e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IOOILHMJ_03943 7.3e-155 yycI S protein conserved in bacteria
IOOILHMJ_03944 4.4e-258 yycH S protein conserved in bacteria
IOOILHMJ_03945 0.0 vicK 2.7.13.3 T Histidine kinase
IOOILHMJ_03946 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOOILHMJ_03951 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOOILHMJ_03952 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOOILHMJ_03953 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IOOILHMJ_03954 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
IOOILHMJ_03956 1.9e-15 yycC K YycC-like protein
IOOILHMJ_03957 2.5e-220 yeaN P COG2807 Cyanate permease
IOOILHMJ_03958 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOOILHMJ_03959 2.2e-73 rplI J binds to the 23S rRNA
IOOILHMJ_03960 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IOOILHMJ_03961 1.6e-158 yybS S membrane
IOOILHMJ_03963 3.3e-83 cotF M Spore coat protein
IOOILHMJ_03964 1.7e-66 ydeP3 K Transcriptional regulator
IOOILHMJ_03965 9.5e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
IOOILHMJ_03966 7.3e-61
IOOILHMJ_03968 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
IOOILHMJ_03969 1.7e-110 K TipAS antibiotic-recognition domain
IOOILHMJ_03970 1.1e-123
IOOILHMJ_03971 1.5e-65 yybH S SnoaL-like domain
IOOILHMJ_03972 3.1e-121 yybG S Pentapeptide repeat-containing protein
IOOILHMJ_03973 6.7e-218 ynfM EGP Major facilitator Superfamily
IOOILHMJ_03974 1.5e-163 yybE K Transcriptional regulator
IOOILHMJ_03975 4.2e-77 yjcF S Acetyltransferase (GNAT) domain
IOOILHMJ_03976 4.7e-74 yybC
IOOILHMJ_03977 3.2e-145 yfiE K LysR substrate binding domain
IOOILHMJ_03978 6.5e-86 E LysE type translocator
IOOILHMJ_03979 5.9e-19 gloA_3 E COG0346 Lactoylglutathione lyase and related lyases
IOOILHMJ_03980 1.6e-125 S Metallo-beta-lactamase superfamily
IOOILHMJ_03981 5.6e-77 yybA 2.3.1.57 K transcriptional
IOOILHMJ_03982 2.1e-68 yjcF S Acetyltransferase (GNAT) domain
IOOILHMJ_03983 4.2e-96 yyaS S Membrane
IOOILHMJ_03984 3e-90 yyaR K Acetyltransferase (GNAT) domain
IOOILHMJ_03985 5.6e-64 yyaQ S YjbR
IOOILHMJ_03986 5.2e-104 yyaP 1.5.1.3 H RibD C-terminal domain
IOOILHMJ_03988 1.5e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IOOILHMJ_03989 4.4e-76 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
IOOILHMJ_03990 2.1e-180 arsB 1.20.4.1 P Arsenic resistance protein
IOOILHMJ_03991 4.1e-72 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOOILHMJ_03992 4.4e-52 arsR K ArsR family transcriptional regulator
IOOILHMJ_03993 3.5e-149 K Helix-turn-helix XRE-family like proteins
IOOILHMJ_03994 4.6e-222 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOOILHMJ_03995 1.3e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IOOILHMJ_03996 1.9e-111 2.1.1.113 L DNA methylase
IOOILHMJ_03997 6.1e-110 L Bpu10I restriction endonuclease
IOOILHMJ_03998 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IOOILHMJ_03999 1.4e-164 yyaK S CAAX protease self-immunity
IOOILHMJ_04000 1.1e-242 EGP Major facilitator superfamily
IOOILHMJ_04001 9.9e-92 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
IOOILHMJ_04002 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOOILHMJ_04003 6.4e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
IOOILHMJ_04004 3.4e-143 xth 3.1.11.2 L exodeoxyribonuclease III
IOOILHMJ_04005 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOOILHMJ_04006 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOOILHMJ_04007 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
IOOILHMJ_04008 1.5e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOOILHMJ_04009 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOOILHMJ_04010 2.3e-33 yyzM S protein conserved in bacteria
IOOILHMJ_04011 3.1e-176 yyaD S Membrane
IOOILHMJ_04012 2.8e-111 yyaC S Sporulation protein YyaC
IOOILHMJ_04013 6e-149 spo0J K Belongs to the ParB family
IOOILHMJ_04014 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
IOOILHMJ_04015 1.5e-74 S Bacterial PH domain
IOOILHMJ_04016 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IOOILHMJ_04017 9.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IOOILHMJ_04018 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOOILHMJ_04019 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOOILHMJ_04020 1.5e-107 jag S single-stranded nucleic acid binding R3H
IOOILHMJ_04021 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOOILHMJ_04022 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)