ORF_ID e_value Gene_name EC_number CAZy COGs Description
LBEOGELJ_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LBEOGELJ_00002 5.3e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LBEOGELJ_00003 1.1e-29 yyzM S Protein conserved in bacteria
LBEOGELJ_00004 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LBEOGELJ_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LBEOGELJ_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LBEOGELJ_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LBEOGELJ_00008 2.7e-61 divIC D Septum formation initiator
LBEOGELJ_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
LBEOGELJ_00011 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LBEOGELJ_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LBEOGELJ_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LBEOGELJ_00014 1.7e-162 L Transposase
LBEOGELJ_00015 1.1e-92 L Transposase
LBEOGELJ_00016 2.7e-28 L transposition
LBEOGELJ_00017 5.5e-81 L Integrase core domain protein
LBEOGELJ_00030 5.3e-11
LBEOGELJ_00036 1.3e-140 mreC M Involved in formation and maintenance of cell shape
LBEOGELJ_00037 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LBEOGELJ_00038 4e-94 usp 3.5.1.28 CBM50 S CHAP domain
LBEOGELJ_00039 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LBEOGELJ_00040 2.9e-218 araT 2.6.1.1 E Aminotransferase
LBEOGELJ_00041 7e-144 recO L Involved in DNA repair and RecF pathway recombination
LBEOGELJ_00042 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LBEOGELJ_00043 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBEOGELJ_00044 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LBEOGELJ_00045 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LBEOGELJ_00046 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LBEOGELJ_00047 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LBEOGELJ_00048 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LBEOGELJ_00049 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LBEOGELJ_00050 1e-90 L transposase activity
LBEOGELJ_00051 3.5e-50 L transposition
LBEOGELJ_00052 2e-32 L Integrase core domain protein
LBEOGELJ_00053 2.3e-161 S CHAP domain
LBEOGELJ_00054 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
LBEOGELJ_00055 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LBEOGELJ_00056 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LBEOGELJ_00057 9.2e-141 1.1.1.169 H Ketopantoate reductase
LBEOGELJ_00058 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LBEOGELJ_00059 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LBEOGELJ_00060 8.2e-70 argR K Regulates arginine biosynthesis genes
LBEOGELJ_00061 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LBEOGELJ_00062 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LBEOGELJ_00063 7e-34 S Protein of unknown function (DUF3021)
LBEOGELJ_00064 1.2e-61 KT phosphorelay signal transduction system
LBEOGELJ_00066 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LBEOGELJ_00068 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LBEOGELJ_00069 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
LBEOGELJ_00070 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
LBEOGELJ_00071 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LBEOGELJ_00072 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
LBEOGELJ_00078 2.6e-10
LBEOGELJ_00081 1.9e-07
LBEOGELJ_00086 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LBEOGELJ_00087 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LBEOGELJ_00088 5.5e-36 XK27_02060 S Transglycosylase associated protein
LBEOGELJ_00089 2.6e-55 badR K DNA-binding transcription factor activity
LBEOGELJ_00090 2.1e-82 S reductase
LBEOGELJ_00091 6.9e-89 L Integrase core domain protein
LBEOGELJ_00092 6.4e-41 L transposition
LBEOGELJ_00094 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
LBEOGELJ_00095 3.5e-79 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LBEOGELJ_00098 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
LBEOGELJ_00099 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LBEOGELJ_00100 1.1e-83 S Putative small multi-drug export protein
LBEOGELJ_00101 6.2e-76 ctsR K Belongs to the CtsR family
LBEOGELJ_00102 0.0 clpC O Belongs to the ClpA ClpB family
LBEOGELJ_00103 2.7e-150 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LBEOGELJ_00104 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LBEOGELJ_00105 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LBEOGELJ_00106 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LBEOGELJ_00107 2e-143 S SseB protein N-terminal domain
LBEOGELJ_00108 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
LBEOGELJ_00109 3.9e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LBEOGELJ_00110 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LBEOGELJ_00113 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LBEOGELJ_00114 3.5e-91 yacP S RNA-binding protein containing a PIN domain
LBEOGELJ_00115 3.4e-155 degV S DegV family
LBEOGELJ_00117 1.8e-31 K helix-turn-helix
LBEOGELJ_00118 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LBEOGELJ_00119 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LBEOGELJ_00120 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
LBEOGELJ_00121 9.3e-239 L Transposase
LBEOGELJ_00122 1.5e-35 K sequence-specific DNA binding
LBEOGELJ_00124 0.0 S Lantibiotic dehydratase, C terminus
LBEOGELJ_00125 1.6e-230 spaC2 V Lanthionine synthetase C family protein
LBEOGELJ_00126 3.3e-183 EGP Major facilitator Superfamily
LBEOGELJ_00127 1.6e-91 3.6.4.12 K Divergent AAA domain protein
LBEOGELJ_00128 4.8e-51 int L Belongs to the 'phage' integrase family
LBEOGELJ_00129 6.6e-105 int L Belongs to the 'phage' integrase family
LBEOGELJ_00130 2.8e-39 S Helix-turn-helix domain
LBEOGELJ_00131 4.9e-173
LBEOGELJ_00133 3.4e-75 isp2 S pathogenesis
LBEOGELJ_00134 2.2e-90 tnp L Transposase
LBEOGELJ_00135 3.3e-225 capA M Bacterial capsule synthesis protein
LBEOGELJ_00136 3.6e-39 gcvR T UPF0237 protein
LBEOGELJ_00137 1.9e-242 XK27_08635 S UPF0210 protein
LBEOGELJ_00138 8.3e-38 ais G alpha-ribazole phosphatase activity
LBEOGELJ_00139 7.9e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LBEOGELJ_00140 7.2e-101 acmA 3.2.1.17 NU amidase activity
LBEOGELJ_00141 5.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LBEOGELJ_00142 1.9e-69 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LBEOGELJ_00143 8.4e-281 dnaK O Heat shock 70 kDa protein
LBEOGELJ_00144 5.6e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LBEOGELJ_00145 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LBEOGELJ_00146 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
LBEOGELJ_00147 3.3e-72 hmpT S cog cog4720
LBEOGELJ_00150 9.9e-19 S Domain of unknown function (DUF4649)
LBEOGELJ_00151 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
LBEOGELJ_00152 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LBEOGELJ_00153 6.5e-87
LBEOGELJ_00154 1.6e-77 sigH K DNA-templated transcription, initiation
LBEOGELJ_00155 3.5e-149 ykuT M mechanosensitive ion channel
LBEOGELJ_00156 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LBEOGELJ_00157 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LBEOGELJ_00158 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LBEOGELJ_00159 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
LBEOGELJ_00160 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
LBEOGELJ_00161 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
LBEOGELJ_00162 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LBEOGELJ_00163 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LBEOGELJ_00164 2.4e-83 nrdI F Belongs to the NrdI family
LBEOGELJ_00165 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LBEOGELJ_00166 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LBEOGELJ_00167 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LBEOGELJ_00168 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LBEOGELJ_00169 5.6e-59 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LBEOGELJ_00170 1.9e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LBEOGELJ_00171 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LBEOGELJ_00172 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LBEOGELJ_00173 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LBEOGELJ_00174 6.5e-202 yhjX P Major Facilitator
LBEOGELJ_00175 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LBEOGELJ_00176 5e-94 V VanZ like family
LBEOGELJ_00179 1e-123 glnQ E abc transporter atp-binding protein
LBEOGELJ_00180 1.8e-276 glnP P ABC transporter
LBEOGELJ_00181 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LBEOGELJ_00182 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LBEOGELJ_00183 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
LBEOGELJ_00184 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LBEOGELJ_00185 6.3e-235 sufD O assembly protein SufD
LBEOGELJ_00186 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LBEOGELJ_00187 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
LBEOGELJ_00188 3.5e-274 sufB O assembly protein SufB
LBEOGELJ_00189 7e-10 oppA E ABC transporter substrate-binding protein
LBEOGELJ_00190 2e-138 oppA E ABC transporter substrate-binding protein
LBEOGELJ_00191 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LBEOGELJ_00192 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LBEOGELJ_00193 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LBEOGELJ_00194 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LBEOGELJ_00195 3e-27 oppD P Belongs to the ABC transporter superfamily
LBEOGELJ_00196 2.5e-32 oppD P Belongs to the ABC transporter superfamily
LBEOGELJ_00197 1.2e-62 oppD P Belongs to the ABC transporter superfamily
LBEOGELJ_00198 7e-43 oppD P Belongs to the ABC transporter superfamily
LBEOGELJ_00199 7.5e-62 oppF P Belongs to the ABC transporter superfamily
LBEOGELJ_00200 3.4e-62 oppF P Belongs to the ABC transporter superfamily
LBEOGELJ_00201 6.4e-23
LBEOGELJ_00202 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LBEOGELJ_00203 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LBEOGELJ_00204 1.9e-223 EGP Major facilitator Superfamily
LBEOGELJ_00205 3.1e-72 adcR K transcriptional
LBEOGELJ_00206 2.2e-136 adcC P ABC transporter, ATP-binding protein
LBEOGELJ_00207 1.6e-127 adcB P ABC transporter (Permease
LBEOGELJ_00208 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
LBEOGELJ_00209 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
LBEOGELJ_00210 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
LBEOGELJ_00211 3.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LBEOGELJ_00212 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
LBEOGELJ_00213 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
LBEOGELJ_00214 1.9e-127 yeeN K transcriptional regulatory protein
LBEOGELJ_00215 9.8e-50 yajC U protein transport
LBEOGELJ_00216 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LBEOGELJ_00217 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
LBEOGELJ_00218 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LBEOGELJ_00219 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LBEOGELJ_00220 0.0 WQ51_06230 S ABC transporter substrate binding protein
LBEOGELJ_00221 5.2e-142 cmpC S abc transporter atp-binding protein
LBEOGELJ_00222 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LBEOGELJ_00223 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LBEOGELJ_00224 4.4e-37 L Transposase
LBEOGELJ_00225 6.4e-18 L transposase activity
LBEOGELJ_00226 1.5e-30 L transposition
LBEOGELJ_00229 4.7e-43
LBEOGELJ_00230 6.8e-56 S TM2 domain
LBEOGELJ_00231 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LBEOGELJ_00232 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LBEOGELJ_00233 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LBEOGELJ_00234 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
LBEOGELJ_00235 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
LBEOGELJ_00236 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
LBEOGELJ_00237 6e-55 cof Q phosphatase activity
LBEOGELJ_00238 6.2e-35 cof Q phosphatase activity
LBEOGELJ_00239 1.6e-137 glcR K transcriptional regulator (DeoR family)
LBEOGELJ_00240 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LBEOGELJ_00241 3.8e-40 K transcriptional
LBEOGELJ_00242 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
LBEOGELJ_00243 6.5e-67 S COG1073 Hydrolases of the alpha beta superfamily
LBEOGELJ_00244 1.1e-65 S COG1073 Hydrolases of the alpha beta superfamily
LBEOGELJ_00245 8.2e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LBEOGELJ_00246 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LBEOGELJ_00247 3.2e-77 yhaI L Membrane
LBEOGELJ_00248 1.7e-259 pepC 3.4.22.40 E aminopeptidase
LBEOGELJ_00249 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LBEOGELJ_00250 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LBEOGELJ_00251 3.1e-95 ypsA S Belongs to the UPF0398 family
LBEOGELJ_00252 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LBEOGELJ_00253 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LBEOGELJ_00254 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
LBEOGELJ_00255 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
LBEOGELJ_00256 2.5e-23
LBEOGELJ_00257 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LBEOGELJ_00258 7.3e-80 XK27_09675 K -acetyltransferase
LBEOGELJ_00259 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LBEOGELJ_00260 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LBEOGELJ_00261 2e-58 L Integrase core domain protein
LBEOGELJ_00262 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LBEOGELJ_00263 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LBEOGELJ_00264 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LBEOGELJ_00265 4.6e-88 XK27_09705 6.1.1.14 S HD superfamily hydrolase
LBEOGELJ_00266 3.3e-97 ybhL S Belongs to the BI1 family
LBEOGELJ_00269 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LBEOGELJ_00270 3.7e-91 K transcriptional regulator
LBEOGELJ_00271 7.6e-36 yneF S UPF0154 protein
LBEOGELJ_00272 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LBEOGELJ_00273 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LBEOGELJ_00274 3.5e-99 XK27_09740 S Phosphoesterase
LBEOGELJ_00275 7.8e-85 ykuL S CBS domain
LBEOGELJ_00276 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
LBEOGELJ_00277 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LBEOGELJ_00278 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LBEOGELJ_00279 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LBEOGELJ_00280 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LBEOGELJ_00281 4.8e-255 trkH P Cation transport protein
LBEOGELJ_00282 4.2e-245 trkA P Potassium transporter peripheral membrane component
LBEOGELJ_00283 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LBEOGELJ_00284 1.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LBEOGELJ_00285 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
LBEOGELJ_00286 5.6e-161 K sequence-specific DNA binding
LBEOGELJ_00287 1.2e-32 V protein secretion by the type I secretion system
LBEOGELJ_00288 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LBEOGELJ_00289 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LBEOGELJ_00290 1.1e-34 V protein secretion by the type I secretion system
LBEOGELJ_00291 1.8e-27 comA V protein secretion by the type I secretion system
LBEOGELJ_00292 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LBEOGELJ_00293 2.6e-47 yhaI L Membrane
LBEOGELJ_00294 1e-55 S Domain of unknown function (DUF4173)
LBEOGELJ_00295 1.2e-94 ureI S AmiS/UreI family transporter
LBEOGELJ_00296 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LBEOGELJ_00297 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LBEOGELJ_00298 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LBEOGELJ_00299 6.6e-78 ureE O enzyme active site formation
LBEOGELJ_00300 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LBEOGELJ_00301 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LBEOGELJ_00302 4.9e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LBEOGELJ_00303 2.7e-177 cbiM P PDGLE domain
LBEOGELJ_00304 1.7e-137 P cobalt transport protein
LBEOGELJ_00305 1.6e-131 cbiO P ABC transporter
LBEOGELJ_00306 5.3e-153 ET amino acid transport
LBEOGELJ_00307 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LBEOGELJ_00308 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
LBEOGELJ_00309 3.8e-205 EGP Transmembrane secretion effector
LBEOGELJ_00310 4e-153 ET amino acid transport
LBEOGELJ_00311 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
LBEOGELJ_00312 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
LBEOGELJ_00313 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
LBEOGELJ_00314 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
LBEOGELJ_00315 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LBEOGELJ_00316 5.2e-98 metI P ABC transporter (Permease
LBEOGELJ_00317 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LBEOGELJ_00318 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
LBEOGELJ_00319 8e-94 S UPF0397 protein
LBEOGELJ_00320 0.0 ykoD P abc transporter atp-binding protein
LBEOGELJ_00321 1.2e-149 cbiQ P cobalt transport
LBEOGELJ_00322 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LBEOGELJ_00323 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
LBEOGELJ_00324 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
LBEOGELJ_00325 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
LBEOGELJ_00326 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
LBEOGELJ_00327 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
LBEOGELJ_00328 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LBEOGELJ_00329 2.8e-282 T PhoQ Sensor
LBEOGELJ_00330 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LBEOGELJ_00331 6.5e-218 dnaB L Replication initiation and membrane attachment
LBEOGELJ_00332 4.4e-166 dnaI L Primosomal protein DnaI
LBEOGELJ_00333 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LBEOGELJ_00335 1.2e-34
LBEOGELJ_00336 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
LBEOGELJ_00337 3e-27 L Integrase core domain protein
LBEOGELJ_00338 3.4e-50 L transposition
LBEOGELJ_00339 5.7e-23 L Transposase
LBEOGELJ_00340 7.8e-28 L transposase activity
LBEOGELJ_00341 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LBEOGELJ_00342 4.2e-62 manO S protein conserved in bacteria
LBEOGELJ_00343 1.2e-166 manN G PTS system mannose fructose sorbose family IID component
LBEOGELJ_00344 1.7e-116 manM G pts system
LBEOGELJ_00345 2.8e-174 manL 2.7.1.191 G pts system
LBEOGELJ_00346 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
LBEOGELJ_00347 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LBEOGELJ_00348 2.1e-247 pbuO S permease
LBEOGELJ_00349 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
LBEOGELJ_00350 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
LBEOGELJ_00351 2.5e-220 brpA K Transcriptional
LBEOGELJ_00352 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
LBEOGELJ_00353 3.1e-212 nusA K Participates in both transcription termination and antitermination
LBEOGELJ_00354 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
LBEOGELJ_00355 1.4e-41 ylxQ J ribosomal protein
LBEOGELJ_00356 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LBEOGELJ_00357 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LBEOGELJ_00358 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
LBEOGELJ_00359 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
LBEOGELJ_00360 2.1e-213 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
LBEOGELJ_00361 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LBEOGELJ_00362 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
LBEOGELJ_00363 3.6e-95 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
LBEOGELJ_00364 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
LBEOGELJ_00365 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LBEOGELJ_00366 1.4e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
LBEOGELJ_00367 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LBEOGELJ_00368 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LBEOGELJ_00369 3.4e-74 ylbF S Belongs to the UPF0342 family
LBEOGELJ_00370 7.1e-46 ylbG S UPF0298 protein
LBEOGELJ_00371 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
LBEOGELJ_00372 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
LBEOGELJ_00373 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
LBEOGELJ_00374 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
LBEOGELJ_00375 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
LBEOGELJ_00376 2.8e-70 acuB S IMP dehydrogenase activity
LBEOGELJ_00377 3.3e-43 acuB S IMP dehydrogenase activity
LBEOGELJ_00378 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LBEOGELJ_00379 6.3e-111 yvyE 3.4.13.9 S YigZ family
LBEOGELJ_00380 1.7e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LBEOGELJ_00381 4.4e-123 comFC S Competence protein
LBEOGELJ_00382 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LBEOGELJ_00390 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
LBEOGELJ_00391 6.4e-108 S Domain of unknown function (DUF1803)
LBEOGELJ_00392 1.3e-101 ygaC J Belongs to the UPF0374 family
LBEOGELJ_00393 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
LBEOGELJ_00394 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LBEOGELJ_00395 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
LBEOGELJ_00396 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
LBEOGELJ_00397 1.9e-115 S Haloacid dehalogenase-like hydrolase
LBEOGELJ_00398 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
LBEOGELJ_00399 4e-72 marR K Transcriptional regulator, MarR family
LBEOGELJ_00400 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LBEOGELJ_00401 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBEOGELJ_00402 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
LBEOGELJ_00403 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LBEOGELJ_00404 1.6e-126 IQ reductase
LBEOGELJ_00405 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LBEOGELJ_00406 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LBEOGELJ_00407 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LBEOGELJ_00408 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LBEOGELJ_00409 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LBEOGELJ_00410 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LBEOGELJ_00411 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LBEOGELJ_00412 5.2e-65 tnp L Transposase
LBEOGELJ_00413 8.9e-202 rny D Endoribonuclease that initiates mRNA decay
LBEOGELJ_00414 1.8e-84 L Transposase
LBEOGELJ_00415 5.6e-114 fruR K transcriptional
LBEOGELJ_00416 5.5e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LBEOGELJ_00417 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
LBEOGELJ_00418 2.2e-49 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
LBEOGELJ_00419 2.7e-126 fruA 2.7.1.202 G phosphotransferase system
LBEOGELJ_00420 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
LBEOGELJ_00421 7.9e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LBEOGELJ_00422 3.7e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LBEOGELJ_00424 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
LBEOGELJ_00425 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LBEOGELJ_00426 1.1e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LBEOGELJ_00427 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LBEOGELJ_00428 6.4e-29 2.3.1.128 K acetyltransferase
LBEOGELJ_00429 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LBEOGELJ_00430 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LBEOGELJ_00431 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LBEOGELJ_00432 2.6e-64 WQ51_03320 S cog cog4835
LBEOGELJ_00433 9.8e-91 XK27_08360 S EDD domain protein, DegV family
LBEOGELJ_00434 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LBEOGELJ_00435 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LBEOGELJ_00436 0.0 yfmR S abc transporter atp-binding protein
LBEOGELJ_00437 1.6e-24 U response to pH
LBEOGELJ_00438 5.9e-140 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
LBEOGELJ_00439 3.8e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
LBEOGELJ_00440 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LBEOGELJ_00441 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LBEOGELJ_00442 1.9e-77 K DNA-binding transcription factor activity
LBEOGELJ_00443 0.0 lmrA1 V abc transporter atp-binding protein
LBEOGELJ_00444 0.0 lmrA2 V abc transporter atp-binding protein
LBEOGELJ_00445 2.2e-18 K Acetyltransferase (GNAT) family
LBEOGELJ_00446 3.2e-78 sptS 2.7.13.3 T Histidine kinase
LBEOGELJ_00447 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LBEOGELJ_00448 3.8e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LBEOGELJ_00449 2e-160 cvfB S Protein conserved in bacteria
LBEOGELJ_00450 1.6e-34 yozE S Belongs to the UPF0346 family
LBEOGELJ_00451 5.1e-119 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
LBEOGELJ_00452 2.3e-61 rlpA M LysM domain protein
LBEOGELJ_00453 8e-191 phoH T phosphate starvation-inducible protein PhoH
LBEOGELJ_00457 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LBEOGELJ_00458 1.8e-164 K transcriptional regulator (lysR family)
LBEOGELJ_00459 3.2e-183 coiA 3.6.4.12 S Competence protein
LBEOGELJ_00460 0.0 pepF E oligoendopeptidase F
LBEOGELJ_00461 7.1e-127 yrrM 2.1.1.104 S O-Methyltransferase
LBEOGELJ_00462 8.6e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
LBEOGELJ_00463 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LBEOGELJ_00464 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LBEOGELJ_00465 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LBEOGELJ_00466 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
LBEOGELJ_00467 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
LBEOGELJ_00468 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LBEOGELJ_00469 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
LBEOGELJ_00470 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LBEOGELJ_00471 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LBEOGELJ_00472 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LBEOGELJ_00473 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LBEOGELJ_00474 4.1e-132 yxkH G deacetylase
LBEOGELJ_00475 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LBEOGELJ_00476 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LBEOGELJ_00477 5.5e-153 rarD S Transporter
LBEOGELJ_00478 2.2e-15 T peptidase
LBEOGELJ_00479 1.5e-13 coiA 3.6.4.12 S Competence protein
LBEOGELJ_00480 5.6e-109 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LBEOGELJ_00481 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LBEOGELJ_00482 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LBEOGELJ_00483 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LBEOGELJ_00484 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
LBEOGELJ_00485 3.3e-78 atpF C ATP synthase F(0) sector subunit b
LBEOGELJ_00486 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LBEOGELJ_00487 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LBEOGELJ_00488 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LBEOGELJ_00489 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LBEOGELJ_00490 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LBEOGELJ_00491 2.8e-230 ftsW D Belongs to the SEDS family
LBEOGELJ_00492 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LBEOGELJ_00493 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LBEOGELJ_00494 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LBEOGELJ_00495 4.2e-161 holB 2.7.7.7 L dna polymerase iii
LBEOGELJ_00496 1.2e-135 yaaT S stage 0 sporulation protein
LBEOGELJ_00497 9.5e-55 yabA L Involved in initiation control of chromosome replication
LBEOGELJ_00498 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LBEOGELJ_00499 7.5e-233 amt P Ammonium Transporter
LBEOGELJ_00500 1.1e-53 glnB K Belongs to the P(II) protein family
LBEOGELJ_00501 4.9e-106 mur1 NU mannosyl-glycoprotein
LBEOGELJ_00502 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
LBEOGELJ_00503 1.2e-92 nptA P COG1283 Na phosphate symporter
LBEOGELJ_00504 8e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LBEOGELJ_00505 4.9e-51
LBEOGELJ_00506 2.2e-25
LBEOGELJ_00507 3.9e-60
LBEOGELJ_00508 6.1e-63 S membrane
LBEOGELJ_00509 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LBEOGELJ_00510 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LBEOGELJ_00511 4.5e-39 ynzC S UPF0291 protein
LBEOGELJ_00512 1.8e-254 cycA E permease
LBEOGELJ_00513 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
LBEOGELJ_00514 4.8e-24 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LBEOGELJ_00515 5.8e-71 pts33BCA G pts system
LBEOGELJ_00516 5.7e-88 pts33BCA G pts system
LBEOGELJ_00517 5.7e-43 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
LBEOGELJ_00518 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LBEOGELJ_00519 1.2e-165 L integrase core domain
LBEOGELJ_00520 5.1e-122 L Transposase
LBEOGELJ_00525 1.8e-167 fhuR K transcriptional regulator (lysR family)
LBEOGELJ_00526 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LBEOGELJ_00527 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LBEOGELJ_00528 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LBEOGELJ_00529 4.9e-227 pyrP F uracil Permease
LBEOGELJ_00530 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LBEOGELJ_00531 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
LBEOGELJ_00532 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
LBEOGELJ_00533 9.3e-239 L Transposase
LBEOGELJ_00534 4.6e-132 2.1.1.223 S Putative SAM-dependent methyltransferase
LBEOGELJ_00535 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBEOGELJ_00536 6.2e-38 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBEOGELJ_00537 1.5e-18 V permease protein
LBEOGELJ_00538 3.6e-32 V efflux transmembrane transporter activity
LBEOGELJ_00539 7e-27 ytrF V efflux transmembrane transporter activity
LBEOGELJ_00540 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LBEOGELJ_00541 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LBEOGELJ_00542 7.6e-189 L Transposase
LBEOGELJ_00543 1.6e-18 L Integrase core domain
LBEOGELJ_00544 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
LBEOGELJ_00545 2.8e-164 hrtB V MacB-like periplasmic core domain
LBEOGELJ_00548 3.4e-91 S MucBP domain
LBEOGELJ_00549 1.9e-49 M YSIRK type signal peptide
LBEOGELJ_00550 0.0 M the current gene model (or a revised gene model) may contain a
LBEOGELJ_00552 0.0 mdlB V abc transporter atp-binding protein
LBEOGELJ_00553 0.0 lmrA V abc transporter atp-binding protein
LBEOGELJ_00554 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LBEOGELJ_00555 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LBEOGELJ_00556 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
LBEOGELJ_00557 2.5e-132 rr02 KT response regulator
LBEOGELJ_00558 1.1e-217 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LBEOGELJ_00559 4.8e-168 V ABC transporter
LBEOGELJ_00560 5.4e-122 sagI S ABC-2 type transporter
LBEOGELJ_00561 1e-195 yceA S Belongs to the UPF0176 family
LBEOGELJ_00562 1.2e-26 XK27_00085 K Transcriptional
LBEOGELJ_00563 4.3e-22
LBEOGELJ_00564 1.7e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
LBEOGELJ_00565 2.5e-113 S VIT family
LBEOGELJ_00566 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LBEOGELJ_00567 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LBEOGELJ_00568 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
LBEOGELJ_00569 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
LBEOGELJ_00570 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LBEOGELJ_00571 4.6e-105 GBS0088 J protein conserved in bacteria
LBEOGELJ_00572 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LBEOGELJ_00573 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LBEOGELJ_00574 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
LBEOGELJ_00575 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LBEOGELJ_00576 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LBEOGELJ_00577 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
LBEOGELJ_00578 2.5e-21
LBEOGELJ_00579 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LBEOGELJ_00581 3.5e-07 U protein secretion
LBEOGELJ_00582 2.1e-50 U protein secretion
LBEOGELJ_00583 1.1e-11 U protein secretion
LBEOGELJ_00584 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
LBEOGELJ_00585 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LBEOGELJ_00586 4.9e-21 XK27_13030
LBEOGELJ_00587 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LBEOGELJ_00588 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LBEOGELJ_00589 9.8e-163 S Protein of unknown function (DUF3114)
LBEOGELJ_00590 1.2e-22 S Protein of unknown function (DUF3114)
LBEOGELJ_00591 1.5e-118 yqfA K protein, Hemolysin III
LBEOGELJ_00592 1e-25 K hmm pf08876
LBEOGELJ_00593 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LBEOGELJ_00594 1.7e-218 mvaS 2.3.3.10 I synthase
LBEOGELJ_00595 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LBEOGELJ_00596 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LBEOGELJ_00597 9.7e-22
LBEOGELJ_00598 5.7e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LBEOGELJ_00599 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
LBEOGELJ_00600 1.3e-249 mmuP E amino acid
LBEOGELJ_00601 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
LBEOGELJ_00602 1.4e-29 S Domain of unknown function (DUF1912)
LBEOGELJ_00603 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
LBEOGELJ_00604 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LBEOGELJ_00605 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LBEOGELJ_00606 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LBEOGELJ_00607 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
LBEOGELJ_00608 4.8e-16 S Protein of unknown function (DUF2969)
LBEOGELJ_00611 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
LBEOGELJ_00614 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
LBEOGELJ_00615 6.1e-70 M Pfam SNARE associated Golgi protein
LBEOGELJ_00616 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
LBEOGELJ_00617 9.3e-59 S oxidoreductase
LBEOGELJ_00618 9.7e-66 S oxidoreductase
LBEOGELJ_00619 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
LBEOGELJ_00620 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LBEOGELJ_00621 0.0 clpE O Belongs to the ClpA ClpB family
LBEOGELJ_00622 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LBEOGELJ_00623 1.3e-34 ykuJ S protein conserved in bacteria
LBEOGELJ_00625 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
LBEOGELJ_00626 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
LBEOGELJ_00627 5.3e-78 feoA P FeoA domain protein
LBEOGELJ_00628 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LBEOGELJ_00629 1.5e-07
LBEOGELJ_00630 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LBEOGELJ_00631 2.2e-45 K sequence-specific DNA binding
LBEOGELJ_00632 1.5e-35 yugF I carboxylic ester hydrolase activity
LBEOGELJ_00633 7.5e-23 I Alpha/beta hydrolase family
LBEOGELJ_00634 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LBEOGELJ_00635 1.6e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LBEOGELJ_00636 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
LBEOGELJ_00637 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LBEOGELJ_00638 5.5e-62 licT K transcriptional antiterminator
LBEOGELJ_00639 6.8e-53 licT K transcriptional antiterminator
LBEOGELJ_00640 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LBEOGELJ_00641 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LBEOGELJ_00642 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LBEOGELJ_00643 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LBEOGELJ_00644 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LBEOGELJ_00645 6e-133 mdtG EGP Major facilitator Superfamily
LBEOGELJ_00646 9.5e-74 mdtG EGP Major facilitator Superfamily
LBEOGELJ_00647 2.6e-33 secG U Preprotein translocase subunit SecG
LBEOGELJ_00648 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LBEOGELJ_00649 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LBEOGELJ_00650 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LBEOGELJ_00651 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
LBEOGELJ_00652 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
LBEOGELJ_00653 4.4e-183 ccpA K Catabolite control protein A
LBEOGELJ_00654 2.8e-28 yyaQ S YjbR
LBEOGELJ_00655 6.6e-101 yyaQ V Protein conserved in bacteria
LBEOGELJ_00656 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LBEOGELJ_00657 1e-78 yueI S Protein of unknown function (DUF1694)
LBEOGELJ_00658 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LBEOGELJ_00659 2e-25 WQ51_00785
LBEOGELJ_00660 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LBEOGELJ_00661 9.9e-219 ywbD 2.1.1.191 J Methyltransferase
LBEOGELJ_00662 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LBEOGELJ_00663 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LBEOGELJ_00664 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LBEOGELJ_00665 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LBEOGELJ_00666 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LBEOGELJ_00667 3.2e-53 yheA S Belongs to the UPF0342 family
LBEOGELJ_00668 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LBEOGELJ_00669 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LBEOGELJ_00670 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LBEOGELJ_00671 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
LBEOGELJ_00672 1.4e-238 msrR K Transcriptional regulator
LBEOGELJ_00673 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
LBEOGELJ_00674 7e-203 I acyl-CoA dehydrogenase
LBEOGELJ_00675 4.5e-97 mip S hydroperoxide reductase activity
LBEOGELJ_00676 5.2e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LBEOGELJ_00677 2.4e-50 J Acetyltransferase (GNAT) domain
LBEOGELJ_00678 5.7e-95
LBEOGELJ_00679 3.4e-194 L Transposase
LBEOGELJ_00680 1.5e-37 L transposase activity
LBEOGELJ_00681 3.2e-66 L COG2801 Transposase and inactivated derivatives
LBEOGELJ_00682 1.2e-73 L COG2801 Transposase and inactivated derivatives
LBEOGELJ_00683 8.9e-11
LBEOGELJ_00684 7.8e-59 S Protein of unknown function (DUF1722)
LBEOGELJ_00685 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
LBEOGELJ_00687 1.2e-32
LBEOGELJ_00688 1.7e-26 S CAAX protease self-immunity
LBEOGELJ_00689 5.5e-42 S CAAX protease self-immunity
LBEOGELJ_00690 5.6e-27 estA E GDSL-like Lipase/Acylhydrolase
LBEOGELJ_00691 2.1e-95
LBEOGELJ_00692 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LBEOGELJ_00693 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LBEOGELJ_00694 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LBEOGELJ_00695 1e-185 S CRISPR-associated protein Csn2 subfamily St
LBEOGELJ_00696 2.7e-146 ycgQ S TIGR03943 family
LBEOGELJ_00697 1.2e-155 XK27_03015 S permease
LBEOGELJ_00699 0.0 yhgF K Transcriptional accessory protein
LBEOGELJ_00700 9.9e-42 pspC KT PspC domain
LBEOGELJ_00701 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LBEOGELJ_00702 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LBEOGELJ_00704 5.5e-69 ytxH S General stress protein
LBEOGELJ_00706 2e-177 yegQ O Peptidase U32
LBEOGELJ_00707 3.4e-252 yegQ O Peptidase U32
LBEOGELJ_00708 8.1e-46 S CHY zinc finger
LBEOGELJ_00709 9.3e-239 L Transposase
LBEOGELJ_00710 1.9e-87 bioY S biotin synthase
LBEOGELJ_00712 1.1e-33 XK27_12190 S protein conserved in bacteria
LBEOGELJ_00713 1.6e-249 L Transposase
LBEOGELJ_00714 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
LBEOGELJ_00715 9e-10
LBEOGELJ_00716 1.3e-66 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
LBEOGELJ_00717 0.0 L helicase
LBEOGELJ_00718 4.3e-222 L Transposase
LBEOGELJ_00719 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LBEOGELJ_00720 1e-163 M LysM domain
LBEOGELJ_00721 7.6e-16
LBEOGELJ_00722 1.5e-174 S hydrolase
LBEOGELJ_00723 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
LBEOGELJ_00724 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LBEOGELJ_00725 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
LBEOGELJ_00726 2.7e-27 P Hemerythrin HHE cation binding domain protein
LBEOGELJ_00727 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LBEOGELJ_00728 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
LBEOGELJ_00729 4.7e-23 MA20_36090 S Protein of unknown function (DUF2974)
LBEOGELJ_00731 2.5e-103 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LBEOGELJ_00732 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LBEOGELJ_00733 1.4e-68
LBEOGELJ_00735 5.3e-08
LBEOGELJ_00736 2.8e-131 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
LBEOGELJ_00737 0.0 S KAP family P-loop domain
LBEOGELJ_00738 3e-131 S Protein conserved in bacteria
LBEOGELJ_00739 9.6e-305 hsdM 2.1.1.72 V type I restriction-modification system
LBEOGELJ_00741 4.8e-61 spd F DNA RNA non-specific endonuclease
LBEOGELJ_00742 9.9e-90 spd F DNA RNA non-specific endonuclease
LBEOGELJ_00743 9e-93 lemA S LemA family
LBEOGELJ_00744 6.4e-133 htpX O Belongs to the peptidase M48B family
LBEOGELJ_00745 1.8e-73 S Psort location CytoplasmicMembrane, score
LBEOGELJ_00746 6.2e-56 S Domain of unknown function (DUF4430)
LBEOGELJ_00747 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LBEOGELJ_00748 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
LBEOGELJ_00749 4.2e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
LBEOGELJ_00750 2e-186 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
LBEOGELJ_00751 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
LBEOGELJ_00752 3.5e-91 dps P Belongs to the Dps family
LBEOGELJ_00753 1.1e-80 perR P Belongs to the Fur family
LBEOGELJ_00754 8.4e-28 yqgQ S protein conserved in bacteria
LBEOGELJ_00755 2.2e-179 glk 2.7.1.2 G Glucokinase
LBEOGELJ_00756 0.0 typA T GTP-binding protein TypA
LBEOGELJ_00758 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LBEOGELJ_00759 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LBEOGELJ_00760 9.7e-171 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LBEOGELJ_00761 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LBEOGELJ_00762 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LBEOGELJ_00763 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LBEOGELJ_00764 6.8e-96 sepF D cell septum assembly
LBEOGELJ_00765 2.6e-34 yggT D integral membrane protein
LBEOGELJ_00766 1.2e-143 ylmH T S4 RNA-binding domain
LBEOGELJ_00767 1.8e-135 divIVA D Cell division protein DivIVA
LBEOGELJ_00768 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LBEOGELJ_00769 5.5e-30
LBEOGELJ_00770 8.4e-10
LBEOGELJ_00771 3.6e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
LBEOGELJ_00772 2e-45 rpmE2 J 50S ribosomal protein L31
LBEOGELJ_00773 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LBEOGELJ_00774 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
LBEOGELJ_00775 3.1e-155 gst O Glutathione S-transferase
LBEOGELJ_00776 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LBEOGELJ_00777 2.4e-112 tdk 2.7.1.21 F thymidine kinase
LBEOGELJ_00778 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LBEOGELJ_00779 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LBEOGELJ_00780 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LBEOGELJ_00781 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LBEOGELJ_00782 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
LBEOGELJ_00783 6.6e-105 pvaA M lytic transglycosylase activity
LBEOGELJ_00784 0.0 yfiB1 V abc transporter atp-binding protein
LBEOGELJ_00785 0.0 XK27_10035 V abc transporter atp-binding protein
LBEOGELJ_00786 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
LBEOGELJ_00787 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LBEOGELJ_00788 3.9e-237 dltB M Membrane protein involved in D-alanine export
LBEOGELJ_00789 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LBEOGELJ_00790 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LBEOGELJ_00791 6.3e-34 L Integrase core domain protein
LBEOGELJ_00792 9.6e-32 L transposition
LBEOGELJ_00793 6.5e-54 L transposition
LBEOGELJ_00794 7.7e-19 L transposase activity
LBEOGELJ_00795 0.0 3.6.3.8 P cation transport ATPase
LBEOGELJ_00796 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
LBEOGELJ_00798 2.9e-12
LBEOGELJ_00800 1.4e-289 S DNA primase
LBEOGELJ_00801 1.2e-149 KL Phage plasmid primase P4 family
LBEOGELJ_00802 3.1e-22
LBEOGELJ_00806 1.8e-19 K Cro/C1-type HTH DNA-binding domain
LBEOGELJ_00807 1e-21 xre K transcriptional
LBEOGELJ_00808 6.9e-220 sip L Belongs to the 'phage' integrase family
LBEOGELJ_00810 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LBEOGELJ_00811 7.3e-166 metF 1.5.1.20 E reductase
LBEOGELJ_00812 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LBEOGELJ_00813 1.7e-94 panT S ECF transporter, substrate-specific component
LBEOGELJ_00814 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LBEOGELJ_00815 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
LBEOGELJ_00816 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LBEOGELJ_00817 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LBEOGELJ_00818 2.8e-40 T PhoQ Sensor
LBEOGELJ_00819 2.2e-43 T PhoQ Sensor
LBEOGELJ_00820 3.6e-88 T PhoQ Sensor
LBEOGELJ_00821 3.9e-122 L Transposase
LBEOGELJ_00822 1.2e-165 L integrase core domain
LBEOGELJ_00823 1.1e-220 L Transposase
LBEOGELJ_00824 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
LBEOGELJ_00825 8.9e-206 potD P spermidine putrescine ABC transporter
LBEOGELJ_00826 3.1e-268 clcA P Chloride transporter, ClC family
LBEOGELJ_00827 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
LBEOGELJ_00828 1.9e-21 L Helix-turn-helix domain
LBEOGELJ_00829 1.1e-82 L Helix-turn-helix domain
LBEOGELJ_00830 9.8e-163 L Integrase core domain protein
LBEOGELJ_00831 1.6e-249 L Transposase
LBEOGELJ_00832 2.1e-30 rpsT J rRNA binding
LBEOGELJ_00833 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
LBEOGELJ_00834 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
LBEOGELJ_00835 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LBEOGELJ_00836 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LBEOGELJ_00837 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LBEOGELJ_00838 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LBEOGELJ_00839 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LBEOGELJ_00840 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LBEOGELJ_00841 8.3e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LBEOGELJ_00842 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
LBEOGELJ_00843 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
LBEOGELJ_00844 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LBEOGELJ_00845 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LBEOGELJ_00846 3.1e-81 ypmB S Protein conserved in bacteria
LBEOGELJ_00847 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LBEOGELJ_00848 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LBEOGELJ_00850 2.4e-30
LBEOGELJ_00851 3e-13
LBEOGELJ_00852 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
LBEOGELJ_00853 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LBEOGELJ_00854 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
LBEOGELJ_00855 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LBEOGELJ_00856 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
LBEOGELJ_00857 4.2e-18 D nuclear chromosome segregation
LBEOGELJ_00858 2.8e-137 yejC S cyclic nucleotide-binding protein
LBEOGELJ_00859 1.2e-163 rapZ S Displays ATPase and GTPase activities
LBEOGELJ_00860 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LBEOGELJ_00861 8.7e-162 whiA K May be required for sporulation
LBEOGELJ_00862 6.4e-168 pepD E Dipeptidase
LBEOGELJ_00863 5.4e-32 cspD K Cold shock protein domain
LBEOGELJ_00864 8e-42 K Cold-Shock Protein
LBEOGELJ_00865 1.2e-165 L integrase core domain
LBEOGELJ_00866 5.1e-122 L Transposase
LBEOGELJ_00867 8.8e-223 L Transposase
LBEOGELJ_00868 0.0 copB 3.6.3.4 P P-type ATPase
LBEOGELJ_00869 2.8e-221 L Transposase
LBEOGELJ_00870 2.9e-190 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LBEOGELJ_00871 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LBEOGELJ_00872 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LBEOGELJ_00873 1.5e-59 cysE 2.3.1.30 E serine acetyltransferase
LBEOGELJ_00874 5.7e-222 L Transposase
LBEOGELJ_00875 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
LBEOGELJ_00876 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
LBEOGELJ_00877 3.7e-157 glcU U Glucose uptake
LBEOGELJ_00878 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
LBEOGELJ_00879 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
LBEOGELJ_00880 7.3e-48 XK27_10720 D peptidase activity
LBEOGELJ_00881 7.5e-35 XK27_10720 D peptidase activity
LBEOGELJ_00882 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
LBEOGELJ_00883 1.7e-08
LBEOGELJ_00885 1.2e-172 yeiH S Membrane
LBEOGELJ_00886 5.5e-119 mur1 NU muramidase
LBEOGELJ_00887 2.4e-83 L transposition
LBEOGELJ_00888 4.5e-166 cpsY K Transcriptional regulator
LBEOGELJ_00889 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LBEOGELJ_00890 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
LBEOGELJ_00891 2e-104 artQ P ABC transporter (Permease
LBEOGELJ_00892 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
LBEOGELJ_00893 2.5e-158 aatB ET ABC transporter substrate-binding protein
LBEOGELJ_00894 1e-137 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LBEOGELJ_00895 2.1e-07
LBEOGELJ_00896 4.1e-26
LBEOGELJ_00897 8.1e-60 adhP 1.1.1.1 C alcohol dehydrogenase
LBEOGELJ_00898 1.7e-17 adhP 1.1.1.1 C alcohol dehydrogenase
LBEOGELJ_00899 7.2e-30 adhP 1.1.1.1 C alcohol dehydrogenase
LBEOGELJ_00900 4.6e-78 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
LBEOGELJ_00901 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LBEOGELJ_00902 2e-126 gntR1 K transcriptional
LBEOGELJ_00903 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LBEOGELJ_00904 2.2e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LBEOGELJ_00905 4.1e-87 niaX
LBEOGELJ_00906 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
LBEOGELJ_00907 1.8e-127 K DNA-binding helix-turn-helix protein
LBEOGELJ_00908 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LBEOGELJ_00909 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LBEOGELJ_00910 8.2e-168 GK ROK family
LBEOGELJ_00911 8.3e-159 dprA LU DNA protecting protein DprA
LBEOGELJ_00912 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LBEOGELJ_00913 1.4e-150 S TraX protein
LBEOGELJ_00914 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LBEOGELJ_00915 2.4e-251 T PhoQ Sensor
LBEOGELJ_00916 1.5e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LBEOGELJ_00917 1.1e-152 XK27_05470 E Methionine synthase
LBEOGELJ_00918 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LBEOGELJ_00919 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LBEOGELJ_00920 2.4e-37 IQ Acetoin reductase
LBEOGELJ_00921 5.9e-45 IQ Acetoin reductase
LBEOGELJ_00923 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LBEOGELJ_00924 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LBEOGELJ_00926 4.3e-222 L Transposase
LBEOGELJ_00928 1.1e-212 pqqE C radical SAM domain protein
LBEOGELJ_00929 4.4e-135 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
LBEOGELJ_00930 6.6e-61 EGP Major facilitator Superfamily
LBEOGELJ_00931 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LBEOGELJ_00932 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
LBEOGELJ_00933 7.3e-13
LBEOGELJ_00934 8e-160 L Transposase
LBEOGELJ_00935 6.4e-104 V ABC transporter (Permease
LBEOGELJ_00936 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LBEOGELJ_00937 1.6e-10
LBEOGELJ_00938 9e-98 K Transcriptional regulator, TetR family
LBEOGELJ_00939 1.8e-159 czcD P cation diffusion facilitator family transporter
LBEOGELJ_00940 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LBEOGELJ_00941 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
LBEOGELJ_00942 6e-08 S Hydrolases of the alpha beta superfamily
LBEOGELJ_00943 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
LBEOGELJ_00944 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
LBEOGELJ_00947 1.2e-143 2.4.2.3 F Phosphorylase superfamily
LBEOGELJ_00948 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
LBEOGELJ_00949 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
LBEOGELJ_00950 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
LBEOGELJ_00951 6.3e-12 dinF V Mate efflux family protein
LBEOGELJ_00953 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LBEOGELJ_00954 1.8e-88 S TraX protein
LBEOGELJ_00955 1.7e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
LBEOGELJ_00956 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LBEOGELJ_00957 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LBEOGELJ_00958 2.8e-185 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LBEOGELJ_00959 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LBEOGELJ_00960 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
LBEOGELJ_00961 0.0 csm1 S CRISPR-associated protein Csm1 family
LBEOGELJ_00962 2.5e-62 csm2 L Csm2 Type III-A
LBEOGELJ_00963 1.6e-117 csm3 L RAMP superfamily
LBEOGELJ_00964 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
LBEOGELJ_00965 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
LBEOGELJ_00967 9.5e-32 csm6 S Psort location Cytoplasmic, score
LBEOGELJ_00968 8e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LBEOGELJ_00969 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LBEOGELJ_00971 1.6e-266 dtpT E transporter
LBEOGELJ_00972 2.3e-62 yecS P ABC transporter (Permease
LBEOGELJ_00973 2.3e-20 yecS P amino acid transport
LBEOGELJ_00975 2e-272 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
LBEOGELJ_00976 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
LBEOGELJ_00977 1.4e-104 yfiF3 K sequence-specific DNA binding
LBEOGELJ_00978 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LBEOGELJ_00979 1.8e-240 agcS E (Alanine) symporter
LBEOGELJ_00980 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LBEOGELJ_00981 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
LBEOGELJ_00982 1.8e-59 Q phosphatase activity
LBEOGELJ_00983 9.3e-62 S haloacid dehalogenase-like hydrolase
LBEOGELJ_00984 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LBEOGELJ_00985 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
LBEOGELJ_00986 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
LBEOGELJ_00987 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
LBEOGELJ_00988 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LBEOGELJ_00989 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LBEOGELJ_00990 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LBEOGELJ_00991 1.9e-43 yktA S Belongs to the UPF0223 family
LBEOGELJ_00992 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LBEOGELJ_00993 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LBEOGELJ_00994 3.3e-158 pstS P phosphate
LBEOGELJ_00995 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
LBEOGELJ_00996 1.2e-155 pstA P phosphate transport system permease
LBEOGELJ_00997 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LBEOGELJ_00998 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LBEOGELJ_00999 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
LBEOGELJ_01000 0.0 pepN 3.4.11.2 E aminopeptidase
LBEOGELJ_01001 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
LBEOGELJ_01002 7.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
LBEOGELJ_01003 1.1e-17
LBEOGELJ_01004 3.7e-09
LBEOGELJ_01005 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LBEOGELJ_01006 2.3e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
LBEOGELJ_01007 2.3e-23 L Transposase
LBEOGELJ_01008 4.6e-25 tatA U protein secretion
LBEOGELJ_01009 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LBEOGELJ_01010 8.8e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
LBEOGELJ_01011 5.6e-233 ycdB P peroxidase
LBEOGELJ_01012 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
LBEOGELJ_01013 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
LBEOGELJ_01014 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
LBEOGELJ_01015 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LBEOGELJ_01016 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LBEOGELJ_01017 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01018 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01019 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01020 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01021 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01022 2.2e-112 3.5.1.28 M GBS Bsp-like repeat
LBEOGELJ_01023 7.9e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LBEOGELJ_01024 6.4e-11 3.5.1.28 NU amidase activity
LBEOGELJ_01025 0.0 lpdA 1.8.1.4 C Dehydrogenase
LBEOGELJ_01026 5.4e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LBEOGELJ_01027 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LBEOGELJ_01028 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LBEOGELJ_01029 3.1e-45 hpk9 2.7.13.3 T protein histidine kinase activity
LBEOGELJ_01030 2.2e-83 2.7.13.3 T protein histidine kinase activity
LBEOGELJ_01031 3.6e-37 2.7.13.3 T protein histidine kinase activity
LBEOGELJ_01032 1.6e-52 2.7.13.3 T protein histidine kinase activity
LBEOGELJ_01033 1.3e-160 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
LBEOGELJ_01034 5.8e-169 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LBEOGELJ_01035 3.2e-110 casE S CRISPR system CASCADE complex protein CasE
LBEOGELJ_01036 3.6e-134 casD S CRISPR system CASCADE complex protein CasD
LBEOGELJ_01037 5.8e-181 casC L CT1975-like protein
LBEOGELJ_01038 6e-103 casB S CRISPR system CASCADE complex protein CasB
LBEOGELJ_01039 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
LBEOGELJ_01040 0.0 cas3 L CRISPR-associated helicase cas3
LBEOGELJ_01041 0.0 S the current gene model (or a revised gene model) may contain a frame shift
LBEOGELJ_01042 2.4e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LBEOGELJ_01043 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LBEOGELJ_01044 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LBEOGELJ_01045 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
LBEOGELJ_01046 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
LBEOGELJ_01047 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
LBEOGELJ_01048 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
LBEOGELJ_01049 1.2e-157 rssA S Phospholipase, patatin family
LBEOGELJ_01050 1.8e-69 estA E GDSL-like protein
LBEOGELJ_01051 3.4e-29 estA E Lysophospholipase L1 and related esterases
LBEOGELJ_01052 1.8e-292 S unusual protein kinase
LBEOGELJ_01053 4.9e-39 S granule-associated protein
LBEOGELJ_01054 2.1e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LBEOGELJ_01055 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LBEOGELJ_01056 1.3e-199 S hmm pf01594
LBEOGELJ_01057 9.5e-89 G Belongs to the phosphoglycerate mutase family
LBEOGELJ_01058 8.4e-69 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
LBEOGELJ_01059 9.2e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LBEOGELJ_01060 5.8e-95 V VanZ like family
LBEOGELJ_01061 5.5e-178 L Transposase
LBEOGELJ_01062 8.2e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
LBEOGELJ_01063 6e-20 epsU S Polysaccharide biosynthesis protein
LBEOGELJ_01064 1.4e-172 epsU S Polysaccharide biosynthesis protein
LBEOGELJ_01065 1.8e-238 cps1C S Polysaccharide biosynthesis protein
LBEOGELJ_01066 8.7e-88 2.7.8.12 GT2 M Glycosyltransferase like family 2
LBEOGELJ_01067 1.8e-32 ywqD 2.7.10.1 D Capsular exopolysaccharide family
LBEOGELJ_01068 4.8e-102 M group 2 family protein
LBEOGELJ_01069 7.7e-100
LBEOGELJ_01070 1.2e-71 cps1D M Domain of unknown function (DUF4422)
LBEOGELJ_01071 5.6e-62 L Transposase DDE domain
LBEOGELJ_01072 2.7e-73 L Transposase DDE domain
LBEOGELJ_01073 2.7e-23 rgpAc GT4 M group 1 family protein
LBEOGELJ_01074 2.7e-255 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
LBEOGELJ_01076 5.9e-110 cpsD D COG0489 ATPases involved in chromosome partitioning
LBEOGELJ_01077 1.1e-105 cps4C M biosynthesis protein
LBEOGELJ_01078 1.5e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
LBEOGELJ_01079 8e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
LBEOGELJ_01080 4.3e-222 L Transposase
LBEOGELJ_01081 2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
LBEOGELJ_01082 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
LBEOGELJ_01083 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
LBEOGELJ_01084 4e-64 clcA_2 P chloride
LBEOGELJ_01085 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LBEOGELJ_01086 8.1e-41 S Protein of unknown function (DUF1697)
LBEOGELJ_01087 8.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LBEOGELJ_01088 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LBEOGELJ_01090 6.1e-22 V Glucan-binding protein C
LBEOGELJ_01091 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
LBEOGELJ_01092 8.2e-276 pepV 3.5.1.18 E Dipeptidase
LBEOGELJ_01093 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LBEOGELJ_01094 6.9e-86 XK27_03610 K Gnat family
LBEOGELJ_01095 4.7e-24 L Transposase
LBEOGELJ_01096 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LBEOGELJ_01097 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LBEOGELJ_01098 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LBEOGELJ_01099 6.6e-122 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LBEOGELJ_01100 3.9e-15 M LysM domain
LBEOGELJ_01101 2.9e-90 ebsA S Family of unknown function (DUF5322)
LBEOGELJ_01102 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LBEOGELJ_01103 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LBEOGELJ_01104 3.7e-224 G COG0457 FOG TPR repeat
LBEOGELJ_01105 6.2e-176 yubA S permease
LBEOGELJ_01106 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
LBEOGELJ_01107 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LBEOGELJ_01108 2.5e-124 ftsE D cell division ATP-binding protein FtsE
LBEOGELJ_01109 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LBEOGELJ_01110 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LBEOGELJ_01111 4.3e-180 yjjH S Calcineurin-like phosphoesterase
LBEOGELJ_01112 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LBEOGELJ_01113 0.0 pacL 3.6.3.8 P cation transport ATPase
LBEOGELJ_01114 2.6e-67 ywiB S Domain of unknown function (DUF1934)
LBEOGELJ_01115 3.6e-45 XK27_00115 2.3.1.128 K acetyltransferase
LBEOGELJ_01116 9.2e-147 yidA S hydrolases of the HAD superfamily
LBEOGELJ_01117 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
LBEOGELJ_01118 5e-35 F Protein of unknown function (DUF454)
LBEOGELJ_01119 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
LBEOGELJ_01120 1.5e-247 vicK 2.7.13.3 T Histidine kinase
LBEOGELJ_01121 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LBEOGELJ_01122 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
LBEOGELJ_01123 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LBEOGELJ_01124 5.9e-118 gltJ P ABC transporter (Permease
LBEOGELJ_01125 5e-111 tcyB_2 P ABC transporter (permease)
LBEOGELJ_01126 2.4e-124 endA F DNA RNA non-specific endonuclease
LBEOGELJ_01127 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
LBEOGELJ_01128 1.1e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LBEOGELJ_01130 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LBEOGELJ_01131 8.3e-28 G Domain of unknown function (DUF4832)
LBEOGELJ_01132 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LBEOGELJ_01133 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LBEOGELJ_01134 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LBEOGELJ_01135 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LBEOGELJ_01136 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LBEOGELJ_01137 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
LBEOGELJ_01140 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LBEOGELJ_01141 4.7e-219 XK27_05110 P chloride
LBEOGELJ_01142 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
LBEOGELJ_01143 6.4e-282 clcA P Chloride transporter, ClC family
LBEOGELJ_01144 2.3e-75 fld C Flavodoxin
LBEOGELJ_01146 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
LBEOGELJ_01147 3.5e-151 estA CE1 S Putative esterase
LBEOGELJ_01148 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LBEOGELJ_01149 1.2e-135 XK27_08845 S abc transporter atp-binding protein
LBEOGELJ_01150 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
LBEOGELJ_01151 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
LBEOGELJ_01152 1.6e-16 S Domain of unknown function (DUF4649)
LBEOGELJ_01154 6.9e-41 Q the current gene model (or a revised gene model) may contain a frame shift
LBEOGELJ_01155 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
LBEOGELJ_01156 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
LBEOGELJ_01158 1.6e-249 L Transposase
LBEOGELJ_01159 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LBEOGELJ_01160 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LBEOGELJ_01161 0.0 dnaE 2.7.7.7 L DNA polymerase
LBEOGELJ_01162 3.2e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
LBEOGELJ_01163 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LBEOGELJ_01164 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LBEOGELJ_01165 2.5e-43 ysdA L Membrane
LBEOGELJ_01166 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LBEOGELJ_01167 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LBEOGELJ_01168 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LBEOGELJ_01169 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
LBEOGELJ_01171 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LBEOGELJ_01172 2.1e-84 ypmS S Protein conserved in bacteria
LBEOGELJ_01173 6e-144 ypmR E lipolytic protein G-D-S-L family
LBEOGELJ_01174 1e-148 DegV S DegV family
LBEOGELJ_01175 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
LBEOGELJ_01176 1.8e-72 argR K Regulates arginine biosynthesis genes
LBEOGELJ_01177 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LBEOGELJ_01178 1.5e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LBEOGELJ_01179 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
LBEOGELJ_01180 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LBEOGELJ_01182 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LBEOGELJ_01183 2.9e-125 dnaD
LBEOGELJ_01184 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LBEOGELJ_01185 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LBEOGELJ_01186 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
LBEOGELJ_01187 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LBEOGELJ_01188 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LBEOGELJ_01189 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LBEOGELJ_01190 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LBEOGELJ_01191 5.4e-197 L transposase, IS4 family
LBEOGELJ_01192 5.6e-240 rodA D Belongs to the SEDS family
LBEOGELJ_01193 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
LBEOGELJ_01194 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LBEOGELJ_01195 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LBEOGELJ_01196 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LBEOGELJ_01197 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LBEOGELJ_01198 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LBEOGELJ_01199 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LBEOGELJ_01200 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LBEOGELJ_01201 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LBEOGELJ_01202 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LBEOGELJ_01204 6.6e-31 L Integrase core domain protein
LBEOGELJ_01205 1.6e-55 L transposition
LBEOGELJ_01206 8.2e-22 L Transposase
LBEOGELJ_01207 5.2e-36 L transposase activity
LBEOGELJ_01208 1.3e-22 XK27_08085
LBEOGELJ_01209 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
LBEOGELJ_01210 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
LBEOGELJ_01211 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
LBEOGELJ_01212 1.1e-121 ylfI S tigr01906
LBEOGELJ_01213 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LBEOGELJ_01214 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
LBEOGELJ_01215 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
LBEOGELJ_01218 9.3e-239 L Transposase
LBEOGELJ_01219 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LBEOGELJ_01220 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LBEOGELJ_01221 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LBEOGELJ_01222 9e-206 yurR 1.4.5.1 E oxidoreductase
LBEOGELJ_01223 6.4e-29 zupT P transporter
LBEOGELJ_01224 1.1e-13 zupT P Mediates zinc uptake. May also transport other divalent cations
LBEOGELJ_01225 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LBEOGELJ_01226 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
LBEOGELJ_01227 1.7e-70 gtrA S GtrA-like protein
LBEOGELJ_01228 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LBEOGELJ_01229 6e-169 ybbR S Protein conserved in bacteria
LBEOGELJ_01230 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LBEOGELJ_01231 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
LBEOGELJ_01232 8.7e-150 cobQ S glutamine amidotransferase
LBEOGELJ_01233 8.8e-81 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LBEOGELJ_01234 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LBEOGELJ_01235 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
LBEOGELJ_01236 0.0 uup S abc transporter atp-binding protein
LBEOGELJ_01237 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
LBEOGELJ_01238 2.7e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
LBEOGELJ_01239 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LBEOGELJ_01240 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
LBEOGELJ_01241 1.6e-249 L Transposase
LBEOGELJ_01242 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LBEOGELJ_01243 7.9e-39 ptsH G phosphocarrier protein Hpr
LBEOGELJ_01244 7.4e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
LBEOGELJ_01245 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
LBEOGELJ_01246 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LBEOGELJ_01247 2.2e-34 nrdH O Glutaredoxin
LBEOGELJ_01248 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LBEOGELJ_01249 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LBEOGELJ_01251 4.2e-71 L Transposase (IS116 IS110 IS902 family)
LBEOGELJ_01252 3.3e-26 L Transposase (IS116 IS110 IS902 family)
LBEOGELJ_01253 6.9e-165 ypuA S secreted protein
LBEOGELJ_01254 8.3e-51 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
LBEOGELJ_01255 8.7e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
LBEOGELJ_01256 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LBEOGELJ_01257 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LBEOGELJ_01258 3.4e-258 noxE P NADH oxidase
LBEOGELJ_01259 1.9e-294 yfmM S abc transporter atp-binding protein
LBEOGELJ_01260 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
LBEOGELJ_01261 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
LBEOGELJ_01262 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
LBEOGELJ_01263 2e-86 S ECF-type riboflavin transporter, S component
LBEOGELJ_01265 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LBEOGELJ_01266 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
LBEOGELJ_01269 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LBEOGELJ_01270 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LBEOGELJ_01271 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LBEOGELJ_01272 0.0 smc D Required for chromosome condensation and partitioning
LBEOGELJ_01273 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LBEOGELJ_01274 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LBEOGELJ_01275 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LBEOGELJ_01276 2.4e-92 pat 2.3.1.183 M acetyltransferase
LBEOGELJ_01277 1.1e-12
LBEOGELJ_01278 8.9e-30
LBEOGELJ_01279 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LBEOGELJ_01280 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LBEOGELJ_01281 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
LBEOGELJ_01282 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
LBEOGELJ_01283 6.9e-30 sdaAA 4.3.1.17 E L-serine dehydratase
LBEOGELJ_01284 4e-102 sdaAA 4.3.1.17 E L-serine dehydratase
LBEOGELJ_01285 7.4e-26
LBEOGELJ_01286 7.6e-146 S ABC-2 family transporter protein
LBEOGELJ_01287 1.1e-98 S transport system, permease component
LBEOGELJ_01288 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LBEOGELJ_01289 2.6e-192 desK 2.7.13.3 T Histidine kinase
LBEOGELJ_01290 1.4e-133 yvfS V ABC-2 type transporter
LBEOGELJ_01291 9.7e-158 XK27_09825 V abc transporter atp-binding protein
LBEOGELJ_01295 2.3e-213 EGP Major facilitator Superfamily
LBEOGELJ_01296 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
LBEOGELJ_01297 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
LBEOGELJ_01298 3.9e-41 3.6.1.55 F NUDIX domain
LBEOGELJ_01300 3.7e-122 S An automated process has identified a potential problem with this gene model
LBEOGELJ_01301 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
LBEOGELJ_01302 1.4e-15 liaI KT membrane
LBEOGELJ_01303 2.6e-30 liaI KT membrane
LBEOGELJ_01304 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
LBEOGELJ_01305 0.0 V ABC transporter (permease)
LBEOGELJ_01306 5.8e-135 macB2 V ABC transporter, ATP-binding protein
LBEOGELJ_01307 1e-163 T Histidine kinase
LBEOGELJ_01308 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LBEOGELJ_01309 5.9e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LBEOGELJ_01310 3.3e-69 pbuX F xanthine permease
LBEOGELJ_01311 9.2e-119 pbuX F xanthine permease
LBEOGELJ_01312 1e-246 norM V Multidrug efflux pump
LBEOGELJ_01313 2.8e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LBEOGELJ_01314 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
LBEOGELJ_01315 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
LBEOGELJ_01316 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
LBEOGELJ_01317 4.8e-25 csbD K CsbD-like
LBEOGELJ_01318 6.2e-228 yfnA E amino acid
LBEOGELJ_01319 5.1e-110 XK27_02070 S nitroreductase
LBEOGELJ_01320 9.5e-150 1.13.11.2 S glyoxalase
LBEOGELJ_01321 5.6e-77 ywnA K Transcriptional regulator
LBEOGELJ_01322 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
LBEOGELJ_01323 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LBEOGELJ_01324 1.4e-110 drgA C Nitroreductase
LBEOGELJ_01325 3e-102 yoaK S Protein of unknown function (DUF1275)
LBEOGELJ_01326 1.2e-160 yvgN C reductase
LBEOGELJ_01327 1e-181 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LBEOGELJ_01328 1.5e-283 XK27_07020 S Belongs to the UPF0371 family
LBEOGELJ_01330 4.8e-55 K response regulator
LBEOGELJ_01331 9.3e-72 S Signal peptide protein, YSIRK family
LBEOGELJ_01332 4.5e-61
LBEOGELJ_01333 5.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LBEOGELJ_01334 1.9e-35
LBEOGELJ_01335 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
LBEOGELJ_01336 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
LBEOGELJ_01337 5.8e-109 MA20_06410 E LysE type translocator
LBEOGELJ_01338 5.6e-08
LBEOGELJ_01339 2.7e-09
LBEOGELJ_01340 0.0 M family 8
LBEOGELJ_01342 7.4e-165 hrtB V MacB-like periplasmic core domain
LBEOGELJ_01343 3.6e-55 devA 3.6.3.25 V abc transporter atp-binding protein
LBEOGELJ_01344 1.1e-151 V MatE
LBEOGELJ_01346 1.5e-109 C Fe-S oxidoreductases
LBEOGELJ_01347 1.2e-176 EGP Major Facilitator Superfamily
LBEOGELJ_01348 1.7e-229 I radical SAM domain protein
LBEOGELJ_01349 4.3e-19 I radical SAM domain protein
LBEOGELJ_01351 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LBEOGELJ_01352 1.5e-149 L Integrase core domain protein
LBEOGELJ_01353 6.1e-18 L transposase activity
LBEOGELJ_01354 8.1e-54 L transposase activity
LBEOGELJ_01356 3.9e-92
LBEOGELJ_01357 0.0 sbcC L ATPase involved in DNA repair
LBEOGELJ_01358 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LBEOGELJ_01359 0.0 lacL 3.2.1.23 G -beta-galactosidase
LBEOGELJ_01360 0.0 lacS G transporter
LBEOGELJ_01361 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LBEOGELJ_01362 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LBEOGELJ_01363 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LBEOGELJ_01364 6.9e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LBEOGELJ_01365 2.3e-184 galR K Transcriptional regulator
LBEOGELJ_01366 2.7e-08 L Integrase core domain protein
LBEOGELJ_01367 1.2e-25 L transposition
LBEOGELJ_01368 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
LBEOGELJ_01369 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
LBEOGELJ_01370 2.5e-101 V abc transporter atp-binding protein
LBEOGELJ_01371 4.3e-40 V abc transporter atp-binding protein
LBEOGELJ_01372 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
LBEOGELJ_01373 6.4e-62 L Transposase
LBEOGELJ_01374 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01375 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01376 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01377 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LBEOGELJ_01378 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LBEOGELJ_01379 7.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LBEOGELJ_01380 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LBEOGELJ_01383 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LBEOGELJ_01384 5.8e-175 vraS 2.7.13.3 T Histidine kinase
LBEOGELJ_01385 3.7e-120 yvqF KT membrane
LBEOGELJ_01386 7e-307 prkC 2.7.11.1 KLT serine threonine protein kinase
LBEOGELJ_01387 2e-132 stp 3.1.3.16 T phosphatase
LBEOGELJ_01388 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LBEOGELJ_01389 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LBEOGELJ_01390 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LBEOGELJ_01391 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
LBEOGELJ_01392 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LBEOGELJ_01393 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LBEOGELJ_01394 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
LBEOGELJ_01395 2.1e-148 supH S overlaps another CDS with the same product name
LBEOGELJ_01396 8.6e-63 yvoA_1 K Transcriptional
LBEOGELJ_01397 2.8e-120 skfE V abc transporter atp-binding protein
LBEOGELJ_01398 3.3e-133 V ATPase activity
LBEOGELJ_01399 4.3e-172 oppF P Belongs to the ABC transporter superfamily
LBEOGELJ_01400 2.2e-204 oppD P Belongs to the ABC transporter superfamily
LBEOGELJ_01401 4.9e-168 amiD P ABC transporter (Permease
LBEOGELJ_01402 4.2e-278 amiC P ABC transporter (Permease
LBEOGELJ_01403 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LBEOGELJ_01404 1.6e-224 L Transposase
LBEOGELJ_01405 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LBEOGELJ_01406 8.1e-45 L Transposase
LBEOGELJ_01407 4.1e-158 L COG2801 Transposase and inactivated derivatives
LBEOGELJ_01408 1.2e-24 oppF P Belongs to the ABC transporter superfamily
LBEOGELJ_01409 3.8e-45 oppF P Belongs to the ABC transporter superfamily
LBEOGELJ_01410 1.4e-40 tatD L Hydrolase, tatd
LBEOGELJ_01411 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
LBEOGELJ_01412 1e-94 L Integrase core domain protein
LBEOGELJ_01413 1.9e-78 L Transposase
LBEOGELJ_01414 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LBEOGELJ_01415 8.3e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LBEOGELJ_01416 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LBEOGELJ_01417 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
LBEOGELJ_01418 1.5e-103 yjbK S Adenylate cyclase
LBEOGELJ_01419 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LBEOGELJ_01420 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
LBEOGELJ_01421 2e-58 XK27_04120 S Putative amino acid metabolism
LBEOGELJ_01422 6.2e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LBEOGELJ_01423 3.9e-130 puuD T peptidase C26
LBEOGELJ_01424 2.4e-119 radC E Belongs to the UPF0758 family
LBEOGELJ_01425 0.0 rgpF M Rhamnan synthesis protein F
LBEOGELJ_01426 1.1e-179 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LBEOGELJ_01427 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LBEOGELJ_01428 1.4e-142 rgpC GM Transport permease protein
LBEOGELJ_01429 1.4e-178 rgpB GT2 M Glycosyltransferase, group 2 family protein
LBEOGELJ_01430 1.2e-224 rgpA GT4 M Domain of unknown function (DUF1972)
LBEOGELJ_01431 6e-139 S Predicted membrane protein (DUF2142)
LBEOGELJ_01432 1.6e-127 2.7.8.12 M transferase activity, transferring glycosyl groups
LBEOGELJ_01433 1.8e-213 amrA S polysaccharide biosynthetic process
LBEOGELJ_01434 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
LBEOGELJ_01435 1.9e-124 ycbB S Glycosyl transferase family 2
LBEOGELJ_01436 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LBEOGELJ_01437 4.1e-245
LBEOGELJ_01438 4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
LBEOGELJ_01439 1.3e-54 yitW K metal-sulfur cluster biosynthetic enzyme
LBEOGELJ_01440 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LBEOGELJ_01441 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LBEOGELJ_01442 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LBEOGELJ_01443 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
LBEOGELJ_01444 4e-201 arcT 2.6.1.1 E Aminotransferase
LBEOGELJ_01445 9.4e-136 ET ABC transporter
LBEOGELJ_01446 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
LBEOGELJ_01447 2.9e-84 mutT 3.6.1.55 F Nudix family
LBEOGELJ_01448 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LBEOGELJ_01450 1.2e-55 V CAAX protease self-immunity
LBEOGELJ_01451 7.6e-32 S CAAX amino terminal protease family protein
LBEOGELJ_01452 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
LBEOGELJ_01453 1.8e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
LBEOGELJ_01454 1.1e-16 XK27_00735
LBEOGELJ_01455 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LBEOGELJ_01457 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LBEOGELJ_01460 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
LBEOGELJ_01461 6.6e-30 ycaO O OsmC-like protein
LBEOGELJ_01463 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
LBEOGELJ_01465 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
LBEOGELJ_01466 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LBEOGELJ_01467 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LBEOGELJ_01468 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LBEOGELJ_01469 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
LBEOGELJ_01470 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LBEOGELJ_01471 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LBEOGELJ_01472 2.6e-109 3.1.3.18 S IA, variant 1
LBEOGELJ_01473 2.5e-116 lrgB M effector of murein hydrolase
LBEOGELJ_01474 7.7e-56 lrgA S Effector of murein hydrolase LrgA
LBEOGELJ_01476 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
LBEOGELJ_01477 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
LBEOGELJ_01478 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LBEOGELJ_01479 3.9e-104 wecD M Acetyltransferase GNAT family
LBEOGELJ_01480 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LBEOGELJ_01481 5.1e-96 GK ROK family
LBEOGELJ_01482 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
LBEOGELJ_01483 5.1e-47 XK27_08050 O stress-induced mitochondrial fusion
LBEOGELJ_01484 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
LBEOGELJ_01485 2.3e-206 potD P spermidine putrescine ABC transporter
LBEOGELJ_01486 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
LBEOGELJ_01487 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
LBEOGELJ_01488 6.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LBEOGELJ_01489 7.8e-171 murB 1.3.1.98 M cell wall formation
LBEOGELJ_01490 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LBEOGELJ_01491 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LBEOGELJ_01492 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
LBEOGELJ_01493 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LBEOGELJ_01494 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
LBEOGELJ_01495 0.0 ydaO E amino acid
LBEOGELJ_01496 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LBEOGELJ_01497 4.1e-37 ylqC L Belongs to the UPF0109 family
LBEOGELJ_01498 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LBEOGELJ_01499 2e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
LBEOGELJ_01500 2.6e-157 xth 3.1.11.2 L exodeoxyribonuclease III
LBEOGELJ_01501 2.1e-74 S QueT transporter
LBEOGELJ_01502 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
LBEOGELJ_01503 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
LBEOGELJ_01504 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LBEOGELJ_01505 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LBEOGELJ_01506 3.7e-85 ccl S cog cog4708
LBEOGELJ_01507 4.9e-160 rbn E Belongs to the UPF0761 family
LBEOGELJ_01508 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
LBEOGELJ_01509 3.3e-231 ytoI K transcriptional regulator containing CBS domains
LBEOGELJ_01510 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
LBEOGELJ_01511 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LBEOGELJ_01512 0.0 comEC S Competence protein ComEC
LBEOGELJ_01513 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
LBEOGELJ_01514 1.7e-142 plsC 2.3.1.51 I Acyltransferase
LBEOGELJ_01515 1.8e-140 nodB3 G deacetylase
LBEOGELJ_01516 7.1e-141 yabB 2.1.1.223 L Methyltransferase
LBEOGELJ_01517 1e-41 yazA L endonuclease containing a URI domain
LBEOGELJ_01518 6.9e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LBEOGELJ_01519 6.7e-154 corA P CorA-like protein
LBEOGELJ_01520 1.9e-62 yjqA S Bacterial PH domain
LBEOGELJ_01521 7.8e-100 thiT S Thiamine transporter
LBEOGELJ_01522 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LBEOGELJ_01523 1.9e-201 yjbB G Permeases of the major facilitator superfamily
LBEOGELJ_01524 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LBEOGELJ_01525 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
LBEOGELJ_01526 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LBEOGELJ_01530 1.1e-155 cjaA ET ABC transporter substrate-binding protein
LBEOGELJ_01531 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
LBEOGELJ_01532 1.3e-114 P ABC transporter (Permease
LBEOGELJ_01533 1e-114 papP P ABC transporter (Permease
LBEOGELJ_01534 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LBEOGELJ_01535 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
LBEOGELJ_01536 0.0 copA 3.6.3.54 P P-type ATPase
LBEOGELJ_01537 2.7e-73 copY K Copper transport repressor, CopY TcrY family
LBEOGELJ_01538 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LBEOGELJ_01539 5.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LBEOGELJ_01540 8.8e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
LBEOGELJ_01541 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LBEOGELJ_01542 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LBEOGELJ_01543 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
LBEOGELJ_01544 6.9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LBEOGELJ_01545 8.1e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
LBEOGELJ_01546 1.7e-51
LBEOGELJ_01547 0.0 ctpE P E1-E2 ATPase
LBEOGELJ_01548 3.9e-26
LBEOGELJ_01549 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LBEOGELJ_01550 9.7e-28 L transposase activity
LBEOGELJ_01551 2.7e-129 K transcriptional regulator, MerR family
LBEOGELJ_01552 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
LBEOGELJ_01553 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
LBEOGELJ_01554 4.8e-63 XK27_02560 S cog cog2151
LBEOGELJ_01555 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LBEOGELJ_01556 7.7e-227 ytfP S Flavoprotein
LBEOGELJ_01558 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LBEOGELJ_01559 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
LBEOGELJ_01560 2.7e-183 ecsB U ABC transporter
LBEOGELJ_01561 2.3e-133 ecsA V abc transporter atp-binding protein
LBEOGELJ_01562 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LBEOGELJ_01563 5.6e-12
LBEOGELJ_01564 2.6e-55 S CD20-like family
LBEOGELJ_01565 7.3e-107
LBEOGELJ_01566 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
LBEOGELJ_01567 6.9e-206 ylbM S Belongs to the UPF0348 family
LBEOGELJ_01568 2e-140 yqeM Q Methyltransferase domain protein
LBEOGELJ_01569 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LBEOGELJ_01570 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LBEOGELJ_01571 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LBEOGELJ_01572 3.5e-49 yhbY J RNA-binding protein
LBEOGELJ_01573 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LBEOGELJ_01574 1.8e-98 yqeG S hydrolase of the HAD superfamily
LBEOGELJ_01575 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LBEOGELJ_01576 1.3e-57
LBEOGELJ_01577 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LBEOGELJ_01578 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LBEOGELJ_01579 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LBEOGELJ_01580 1.8e-23 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
LBEOGELJ_01581 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
LBEOGELJ_01582 4.4e-255 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LBEOGELJ_01583 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LBEOGELJ_01584 4.8e-154 hlpA M Belongs to the NlpA lipoprotein family
LBEOGELJ_01585 6.8e-101 pncA Q isochorismatase
LBEOGELJ_01586 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LBEOGELJ_01587 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
LBEOGELJ_01588 2.4e-75 XK27_03180 T universal stress protein
LBEOGELJ_01591 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LBEOGELJ_01592 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
LBEOGELJ_01593 1.2e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
LBEOGELJ_01594 0.0 yjcE P NhaP-type Na H and K H antiporters
LBEOGELJ_01596 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
LBEOGELJ_01597 1.3e-184 yhcC S radical SAM protein
LBEOGELJ_01598 2.2e-196 ylbL T Belongs to the peptidase S16 family
LBEOGELJ_01599 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LBEOGELJ_01600 2.5e-92 rsmD 2.1.1.171 L Methyltransferase
LBEOGELJ_01601 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LBEOGELJ_01602 3.2e-09 S Protein of unknown function (DUF4059)
LBEOGELJ_01603 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
LBEOGELJ_01604 4.7e-163 yxeN P ABC transporter (Permease
LBEOGELJ_01605 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LBEOGELJ_01607 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LBEOGELJ_01608 0.0 pflB 2.3.1.54 C formate acetyltransferase'
LBEOGELJ_01609 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
LBEOGELJ_01610 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LBEOGELJ_01611 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
LBEOGELJ_01612 2.9e-87 D nuclear chromosome segregation
LBEOGELJ_01613 1.5e-127 ybbM S transport system, permease component
LBEOGELJ_01614 3.6e-117 ybbL S abc transporter atp-binding protein
LBEOGELJ_01615 6.5e-184 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
LBEOGELJ_01616 4.6e-140 cppA E CppA N-terminal
LBEOGELJ_01617 5e-44 V CAAX protease self-immunity
LBEOGELJ_01618 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
LBEOGELJ_01619 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LBEOGELJ_01622 3e-47 spiA K sequence-specific DNA binding
LBEOGELJ_01623 2.9e-28 blpT
LBEOGELJ_01624 6.7e-98 blpT
LBEOGELJ_01625 5.1e-122 L Transposase
LBEOGELJ_01626 1.2e-165 L integrase core domain
LBEOGELJ_01631 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
LBEOGELJ_01634 8.9e-133 agrA KT phosphorelay signal transduction system
LBEOGELJ_01635 2.5e-234 blpH 2.7.13.3 T protein histidine kinase activity
LBEOGELJ_01637 7.3e-237 mesE M Transport protein ComB
LBEOGELJ_01638 9.3e-281 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LBEOGELJ_01639 2.8e-108 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LBEOGELJ_01640 0.0 mdlB V abc transporter atp-binding protein
LBEOGELJ_01641 0.0 mdlA V abc transporter atp-binding protein
LBEOGELJ_01643 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
LBEOGELJ_01644 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LBEOGELJ_01645 2.3e-72 yutD J protein conserved in bacteria
LBEOGELJ_01646 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LBEOGELJ_01648 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LBEOGELJ_01649 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LBEOGELJ_01650 0.0 ftsI 3.4.16.4 M penicillin-binding protein
LBEOGELJ_01651 4.3e-47 ftsL D cell division protein FtsL
LBEOGELJ_01652 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LBEOGELJ_01653 1.6e-65
LBEOGELJ_01654 7.4e-27
LBEOGELJ_01655 2.6e-30
LBEOGELJ_01657 8.7e-33 yhaI J Protein of unknown function (DUF805)
LBEOGELJ_01658 4.5e-18 D nuclear chromosome segregation
LBEOGELJ_01659 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LBEOGELJ_01660 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LBEOGELJ_01661 2.2e-285 XK27_00765
LBEOGELJ_01662 8.1e-134 ecsA_2 V abc transporter atp-binding protein
LBEOGELJ_01663 5.2e-125 S Protein of unknown function (DUF554)
LBEOGELJ_01664 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LBEOGELJ_01665 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LBEOGELJ_01666 2.6e-121 liaI S membrane
LBEOGELJ_01667 5.2e-75 XK27_02470 K LytTr DNA-binding domain
LBEOGELJ_01668 3.6e-66 KT response to antibiotic
LBEOGELJ_01669 5.2e-81 yebC M Membrane
LBEOGELJ_01670 2.9e-18 yebC M Membrane
LBEOGELJ_01671 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
LBEOGELJ_01672 6.2e-174 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LBEOGELJ_01674 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LBEOGELJ_01675 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LBEOGELJ_01676 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LBEOGELJ_01677 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LBEOGELJ_01678 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LBEOGELJ_01679 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LBEOGELJ_01681 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
LBEOGELJ_01682 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
LBEOGELJ_01683 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
LBEOGELJ_01684 4.1e-291 scrB 3.2.1.26 GH32 G invertase
LBEOGELJ_01685 2.2e-179 scrR K Transcriptional
LBEOGELJ_01686 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBEOGELJ_01687 3.4e-62 yqhY S protein conserved in bacteria
LBEOGELJ_01688 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LBEOGELJ_01689 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
LBEOGELJ_01690 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
LBEOGELJ_01692 8e-44 V 'abc transporter, ATP-binding protein
LBEOGELJ_01693 3.8e-58 V 'abc transporter, ATP-binding protein
LBEOGELJ_01696 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LBEOGELJ_01697 2e-169 corA P COG0598 Mg2 and Co2 transporters
LBEOGELJ_01698 3.1e-124 XK27_01040 S Pfam PF06570
LBEOGELJ_01700 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LBEOGELJ_01701 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LBEOGELJ_01702 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
LBEOGELJ_01703 3.6e-41 XK27_05745
LBEOGELJ_01704 2.5e-230 mutY L A G-specific adenine glycosylase
LBEOGELJ_01709 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LBEOGELJ_01710 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LBEOGELJ_01711 1e-93 cvpA S toxin biosynthetic process
LBEOGELJ_01712 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LBEOGELJ_01713 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LBEOGELJ_01714 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LBEOGELJ_01715 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LBEOGELJ_01716 2e-47 azlD E branched-chain amino acid
LBEOGELJ_01717 1.8e-114 azlC E AzlC protein
LBEOGELJ_01718 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LBEOGELJ_01719 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LBEOGELJ_01720 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
LBEOGELJ_01721 2.5e-33 ykzG S Belongs to the UPF0356 family
LBEOGELJ_01722 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LBEOGELJ_01723 2.7e-40 pscB M CHAP domain protein
LBEOGELJ_01724 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
LBEOGELJ_01725 8.5e-63 glnR K Transcriptional regulator
LBEOGELJ_01726 1.3e-87 S Fusaric acid resistance protein-like
LBEOGELJ_01727 3e-13
LBEOGELJ_01728 8.9e-30
LBEOGELJ_01729 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LBEOGELJ_01730 3.2e-42 L Transposase
LBEOGELJ_01731 1.9e-46 L transposase activity
LBEOGELJ_01732 7.4e-23 L Transposase
LBEOGELJ_01733 1.8e-56 L transposition
LBEOGELJ_01734 9.1e-83 L Integrase core domain protein
LBEOGELJ_01735 2.9e-102 L Transposase
LBEOGELJ_01736 1.7e-111 L Transposase
LBEOGELJ_01737 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LBEOGELJ_01738 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LBEOGELJ_01739 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LBEOGELJ_01740 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LBEOGELJ_01741 1.1e-142 purR 2.4.2.7 F operon repressor
LBEOGELJ_01742 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
LBEOGELJ_01743 6.9e-173 rmuC S RmuC domain protein
LBEOGELJ_01744 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
LBEOGELJ_01745 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LBEOGELJ_01746 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LBEOGELJ_01748 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LBEOGELJ_01749 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LBEOGELJ_01750 4.1e-144 tatD L Hydrolase, tatd
LBEOGELJ_01751 1.9e-74 yccU S CoA-binding protein
LBEOGELJ_01752 4.8e-51 trxA O Belongs to the thioredoxin family
LBEOGELJ_01753 1.9e-141 S Macro domain protein
LBEOGELJ_01754 2e-09 L thioesterase
LBEOGELJ_01755 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
LBEOGELJ_01758 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LBEOGELJ_01759 1e-33 L Transposase
LBEOGELJ_01760 1e-13 rpmH J Ribosomal protein L34
LBEOGELJ_01761 1.6e-249 L Transposase
LBEOGELJ_01762 2e-186 jag S RNA-binding protein
LBEOGELJ_01763 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LBEOGELJ_01764 7.6e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LBEOGELJ_01765 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
LBEOGELJ_01766 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LBEOGELJ_01767 6e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LBEOGELJ_01768 2.8e-79 amiA E transmembrane transport
LBEOGELJ_01769 4.2e-74 amiA E transmembrane transport
LBEOGELJ_01770 1.8e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LBEOGELJ_01771 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LBEOGELJ_01772 9.2e-51 S Protein of unknown function (DUF3397)
LBEOGELJ_01773 6.6e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
LBEOGELJ_01774 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
LBEOGELJ_01775 1.8e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
LBEOGELJ_01776 1.7e-221 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LBEOGELJ_01777 5.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LBEOGELJ_01778 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
LBEOGELJ_01779 4.3e-77 XK27_09620 S reductase
LBEOGELJ_01780 9e-62 XK27_09615 C reductase
LBEOGELJ_01781 2.3e-141 XK27_09615 C reductase
LBEOGELJ_01782 3.2e-62 fnt P Formate nitrite transporter
LBEOGELJ_01783 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
LBEOGELJ_01784 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LBEOGELJ_01785 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LBEOGELJ_01786 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LBEOGELJ_01787 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LBEOGELJ_01788 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LBEOGELJ_01789 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LBEOGELJ_01790 2.7e-48 S glycolate biosynthetic process
LBEOGELJ_01791 1.3e-63 S phosphatase activity
LBEOGELJ_01792 7e-158 rrmA 2.1.1.187 Q methyltransferase
LBEOGELJ_01794 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LBEOGELJ_01795 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LBEOGELJ_01796 6.4e-37 yeeD O sulfur carrier activity
LBEOGELJ_01797 1e-190 yeeE S Sulphur transport
LBEOGELJ_01798 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LBEOGELJ_01799 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LBEOGELJ_01800 4.1e-09 S Domain of unknown function (DUF4651)
LBEOGELJ_01801 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LBEOGELJ_01802 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LBEOGELJ_01803 1.8e-111 S CAAX amino terminal protease family protein
LBEOGELJ_01805 5e-67 V CAAX protease self-immunity
LBEOGELJ_01806 1.4e-33 V CAAX protease self-immunity
LBEOGELJ_01808 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LBEOGELJ_01809 5.9e-177 ytxK 2.1.1.72 L DNA methylase
LBEOGELJ_01810 2e-12 comGF U Putative Competence protein ComGF
LBEOGELJ_01811 1.5e-71 comGF U Competence protein ComGF
LBEOGELJ_01812 1.1e-15 NU Type II secretory pathway pseudopilin
LBEOGELJ_01813 1.8e-57 cglD NU Competence protein
LBEOGELJ_01814 8.5e-43 comGC U Required for transformation and DNA binding
LBEOGELJ_01815 3e-145 cglB NU type II secretion system
LBEOGELJ_01816 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LBEOGELJ_01817 2.9e-68 S cog cog4699
LBEOGELJ_01818 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LBEOGELJ_01819 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LBEOGELJ_01820 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LBEOGELJ_01821 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LBEOGELJ_01822 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LBEOGELJ_01823 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
LBEOGELJ_01824 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
LBEOGELJ_01825 1.5e-280 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LBEOGELJ_01826 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LBEOGELJ_01827 9.9e-305 yloV S kinase related to dihydroxyacetone kinase
LBEOGELJ_01828 1.8e-57 asp S cog cog1302
LBEOGELJ_01829 3.2e-226 norN V Mate efflux family protein
LBEOGELJ_01830 1.9e-278 thrC 4.2.3.1 E Threonine synthase
LBEOGELJ_01831 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LBEOGELJ_01832 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
LBEOGELJ_01833 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LBEOGELJ_01834 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LBEOGELJ_01835 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
LBEOGELJ_01836 0.0 pepO 3.4.24.71 O Peptidase family M13
LBEOGELJ_01837 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LBEOGELJ_01838 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LBEOGELJ_01839 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LBEOGELJ_01840 1.4e-54 treB 2.7.1.201 G PTS System
LBEOGELJ_01841 5.8e-21 treR K DNA-binding transcription factor activity
LBEOGELJ_01842 1.2e-85 treR K trehalose operon
LBEOGELJ_01843 3.3e-95 ywlG S Belongs to the UPF0340 family
LBEOGELJ_01845 2.7e-13 L PFAM Integrase, catalytic core
LBEOGELJ_01846 4.2e-72 L PFAM Integrase, catalytic core
LBEOGELJ_01847 3.1e-87 L Phage integrase family
LBEOGELJ_01848 5.7e-46 S Domain of unknown function (DUF4298)
LBEOGELJ_01849 4.5e-61 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
LBEOGELJ_01850 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LBEOGELJ_01851 3.9e-141 3.1.21.3 V Type I restriction modification DNA specificity domain
LBEOGELJ_01852 2.4e-300 hsdM 2.1.1.72 V HsdM N-terminal domain
LBEOGELJ_01853 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
LBEOGELJ_01854 8.2e-205 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LBEOGELJ_01855 2.4e-26
LBEOGELJ_01856 2e-222 L Transposase
LBEOGELJ_01857 1e-140 L DNA integration
LBEOGELJ_01858 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
LBEOGELJ_01860 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
LBEOGELJ_01861 3.6e-64 6.3.2.2 H gamma-glutamylcysteine synthetase
LBEOGELJ_01862 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
LBEOGELJ_01863 3.3e-09 L PFAM Integrase, catalytic core
LBEOGELJ_01864 1.8e-111 L PFAM Integrase, catalytic core
LBEOGELJ_01865 3.3e-62 rplQ J ribosomal protein l17
LBEOGELJ_01866 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LBEOGELJ_01867 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LBEOGELJ_01868 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LBEOGELJ_01869 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LBEOGELJ_01870 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LBEOGELJ_01871 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LBEOGELJ_01872 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LBEOGELJ_01873 4.4e-58 rplO J binds to the 23S rRNA
LBEOGELJ_01874 2.5e-23 rpmD J ribosomal protein l30
LBEOGELJ_01875 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LBEOGELJ_01876 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LBEOGELJ_01877 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LBEOGELJ_01878 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LBEOGELJ_01879 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LBEOGELJ_01880 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LBEOGELJ_01881 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LBEOGELJ_01882 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LBEOGELJ_01883 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LBEOGELJ_01884 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
LBEOGELJ_01885 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LBEOGELJ_01886 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LBEOGELJ_01887 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LBEOGELJ_01888 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LBEOGELJ_01889 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LBEOGELJ_01890 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LBEOGELJ_01891 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
LBEOGELJ_01892 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LBEOGELJ_01893 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
LBEOGELJ_01894 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LBEOGELJ_01895 0.0 XK27_09800 I Acyltransferase
LBEOGELJ_01896 1.7e-35 XK27_09805 S MORN repeat protein
LBEOGELJ_01897 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LBEOGELJ_01898 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LBEOGELJ_01899 8.8e-83 adk 2.7.4.3 F topology modulation protein
LBEOGELJ_01900 3.1e-172 yxaM EGP Major facilitator Superfamily
LBEOGELJ_01901 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
LBEOGELJ_01902 3.1e-220 L Transposase
LBEOGELJ_01904 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LBEOGELJ_01905 1.5e-156 KLT serine threonine protein kinase
LBEOGELJ_01906 6.5e-54 L Transposase
LBEOGELJ_01907 1.2e-149 L Transposase
LBEOGELJ_01908 1.1e-189 KLT serine threonine protein kinase
LBEOGELJ_01909 2.1e-280 V ABC transporter
LBEOGELJ_01910 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LBEOGELJ_01911 1.4e-127 Z012_04635 K sequence-specific DNA binding
LBEOGELJ_01913 6.3e-16 C Radical SAM
LBEOGELJ_01914 3.4e-191 C Radical SAM
LBEOGELJ_01915 3.9e-287 V ABC transporter transmembrane region
LBEOGELJ_01916 1.3e-60 K sequence-specific DNA binding
LBEOGELJ_01917 3.1e-14 K Cro/C1-type HTH DNA-binding domain
LBEOGELJ_01918 1.3e-36 L Replication initiation factor
LBEOGELJ_01919 1.4e-107 L Replication initiation factor
LBEOGELJ_01920 1.9e-18 S Domain of unknown function (DUF3173)
LBEOGELJ_01921 3.5e-216 int L Belongs to the 'phage' integrase family
LBEOGELJ_01923 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
LBEOGELJ_01924 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LBEOGELJ_01925 2.8e-44 yrzL S Belongs to the UPF0297 family
LBEOGELJ_01926 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LBEOGELJ_01927 4.2e-44 yrzB S Belongs to the UPF0473 family
LBEOGELJ_01928 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
LBEOGELJ_01929 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LBEOGELJ_01930 7.5e-14
LBEOGELJ_01931 2.6e-91 XK27_10930 K acetyltransferase
LBEOGELJ_01932 1.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LBEOGELJ_01933 1.8e-147 yaaA S Belongs to the UPF0246 family
LBEOGELJ_01934 9.9e-169 XK27_01785 S cog cog1284
LBEOGELJ_01935 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LBEOGELJ_01937 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
LBEOGELJ_01938 5.7e-52 metE 2.1.1.14 E Methionine synthase
LBEOGELJ_01939 7.6e-64 metE 2.1.1.14 E Methionine synthase
LBEOGELJ_01940 9.2e-36 metE 2.1.1.14 E Methionine synthase
LBEOGELJ_01941 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LBEOGELJ_01942 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LBEOGELJ_01945 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
LBEOGELJ_01946 2.7e-95 S Hydrophobic domain protein
LBEOGELJ_01948 4.3e-222 L Transposase
LBEOGELJ_01949 3.7e-27 S Membrane
LBEOGELJ_01950 3.1e-101
LBEOGELJ_01951 1.8e-23 S Small integral membrane protein
LBEOGELJ_01952 4.3e-71 M Protein conserved in bacteria
LBEOGELJ_01953 4.9e-12 K CsbD-like
LBEOGELJ_01954 7.2e-95 nudL L hydrolase
LBEOGELJ_01955 3.4e-13 nudL L hydrolase
LBEOGELJ_01956 4.3e-222 L Transposase
LBEOGELJ_01957 4e-19 K negative regulation of transcription, DNA-templated
LBEOGELJ_01958 1.7e-23 K negative regulation of transcription, DNA-templated
LBEOGELJ_01960 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
LBEOGELJ_01961 1.8e-88 S Putative adhesin
LBEOGELJ_01962 3.9e-161 XK27_06930 V domain protein
LBEOGELJ_01963 6.4e-96 XK27_06935 K transcriptional regulator
LBEOGELJ_01964 4.8e-55 ypaA M Membrane
LBEOGELJ_01965 2.7e-08
LBEOGELJ_01966 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LBEOGELJ_01967 8.2e-48 veg S Biofilm formation stimulator VEG
LBEOGELJ_01968 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LBEOGELJ_01969 3.9e-70 rplI J binds to the 23S rRNA
LBEOGELJ_01970 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LBEOGELJ_01971 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LBEOGELJ_01972 1.5e-77 F NUDIX domain
LBEOGELJ_01973 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LBEOGELJ_01974 0.0 S Bacterial membrane protein, YfhO
LBEOGELJ_01975 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
LBEOGELJ_01976 3.1e-93 lytE M LysM domain protein
LBEOGELJ_01977 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LBEOGELJ_01978 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LBEOGELJ_01979 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LBEOGELJ_01980 6.9e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LBEOGELJ_01981 3.7e-138 ymfM S sequence-specific DNA binding
LBEOGELJ_01982 1.4e-242 ymfH S Peptidase M16
LBEOGELJ_01983 1.4e-234 ymfF S Peptidase M16
LBEOGELJ_01984 1.8e-43 yaaA S S4 domain protein YaaA
LBEOGELJ_01985 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LBEOGELJ_01986 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LBEOGELJ_01987 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LBEOGELJ_01988 1.1e-153 yvjA S membrane
LBEOGELJ_01989 6.7e-306 ybiT S abc transporter atp-binding protein
LBEOGELJ_01990 0.0 XK27_10405 S Bacterial membrane protein YfhO
LBEOGELJ_01994 2.8e-58 yoaK S Psort location CytoplasmicMembrane, score
LBEOGELJ_01995 1.4e-45 yoaK S Protein of unknown function (DUF1275)
LBEOGELJ_01996 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LBEOGELJ_01997 5.3e-194 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
LBEOGELJ_01998 1e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)