ORF_ID e_value Gene_name EC_number CAZy COGs Description
PKGKOOFP_00001 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PKGKOOFP_00002 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PKGKOOFP_00003 9e-20 yaaA S S4 domain protein YaaA
PKGKOOFP_00004 4.2e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PKGKOOFP_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PKGKOOFP_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PKGKOOFP_00007 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
PKGKOOFP_00008 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PKGKOOFP_00009 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PKGKOOFP_00010 7.3e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PKGKOOFP_00011 1.1e-115 S Glycosyl transferase family 2
PKGKOOFP_00012 7.4e-64 D peptidase
PKGKOOFP_00013 0.0 asnB 6.3.5.4 E Asparagine synthase
PKGKOOFP_00014 5.5e-61 yiiE S Protein of unknown function (DUF1211)
PKGKOOFP_00015 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PKGKOOFP_00016 2.2e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PKGKOOFP_00017 2.1e-17 yneR
PKGKOOFP_00018 2.1e-229 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PKGKOOFP_00019 1.9e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
PKGKOOFP_00020 2.4e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PKGKOOFP_00021 4.9e-152 mdtG EGP Major facilitator Superfamily
PKGKOOFP_00022 5.9e-15 yobS K transcriptional regulator
PKGKOOFP_00023 2.8e-109 glcU U sugar transport
PKGKOOFP_00024 3.4e-170 yjjP S Putative threonine/serine exporter
PKGKOOFP_00025 1.8e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
PKGKOOFP_00026 1.7e-96 yicL EG EamA-like transporter family
PKGKOOFP_00027 6.7e-222 pepF E Oligopeptidase F
PKGKOOFP_00028 1.2e-98 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PKGKOOFP_00029 2.9e-178 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PKGKOOFP_00030 1.5e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
PKGKOOFP_00031 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PKGKOOFP_00032 2.8e-24 relB L RelB antitoxin
PKGKOOFP_00033 4.9e-172 S Putative peptidoglycan binding domain
PKGKOOFP_00034 7.1e-32 K Transcriptional regulator, MarR family
PKGKOOFP_00035 2.4e-216 XK27_09600 V ABC transporter, ATP-binding protein
PKGKOOFP_00036 2.9e-241 V ABC transporter transmembrane region
PKGKOOFP_00037 5.5e-107 yxeH S hydrolase
PKGKOOFP_00038 9e-114 K response regulator
PKGKOOFP_00039 1.5e-272 vicK 2.7.13.3 T Histidine kinase
PKGKOOFP_00040 2.7e-103 yycH S YycH protein
PKGKOOFP_00041 1.3e-79 yycI S YycH protein
PKGKOOFP_00042 5.1e-16 yyaQ S YjbR
PKGKOOFP_00043 1.7e-116 vicX 3.1.26.11 S domain protein
PKGKOOFP_00044 1.8e-144 htrA 3.4.21.107 O serine protease
PKGKOOFP_00045 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PKGKOOFP_00046 4.4e-40 1.6.5.2 GM NAD(P)H-binding
PKGKOOFP_00047 3.3e-25 K MarR family transcriptional regulator
PKGKOOFP_00048 2.3e-87 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
PKGKOOFP_00049 1.5e-28 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PKGKOOFP_00050 6.1e-07 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PKGKOOFP_00052 6.1e-207 G glycerol-3-phosphate transporter
PKGKOOFP_00053 3.8e-29 L Helix-turn-helix domain
PKGKOOFP_00054 3.6e-69 L HTH-like domain
PKGKOOFP_00055 2.1e-71 L PFAM transposase IS200-family protein
PKGKOOFP_00056 1e-214 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PKGKOOFP_00057 3e-147 mepA V MATE efflux family protein
PKGKOOFP_00058 1.1e-150 lsa S ABC transporter
PKGKOOFP_00059 1.4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PKGKOOFP_00060 6.8e-109 puuD S peptidase C26
PKGKOOFP_00061 6.4e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PKGKOOFP_00062 1.1e-25
PKGKOOFP_00063 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
PKGKOOFP_00064 5.1e-60 uspA T Universal stress protein family
PKGKOOFP_00066 2.1e-210 glnP P ABC transporter
PKGKOOFP_00067 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PKGKOOFP_00068 3.9e-147 scrR K helix_turn _helix lactose operon repressor
PKGKOOFP_00069 2.6e-216 scrB 3.2.1.26 GH32 G invertase
PKGKOOFP_00070 3.1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
PKGKOOFP_00071 1.6e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PKGKOOFP_00072 1.6e-114 ntpJ P Potassium uptake protein
PKGKOOFP_00073 2.8e-58 ktrA P TrkA-N domain
PKGKOOFP_00074 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PKGKOOFP_00075 7.5e-37 M Glycosyltransferase group 2 family protein
PKGKOOFP_00076 1.4e-19
PKGKOOFP_00077 8.1e-95 S Predicted membrane protein (DUF2207)
PKGKOOFP_00078 1.8e-53 bioY S BioY family
PKGKOOFP_00079 1.6e-181 lmrB EGP Major facilitator Superfamily
PKGKOOFP_00080 6.3e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PKGKOOFP_00081 1.3e-73 glcR K DeoR C terminal sensor domain
PKGKOOFP_00082 5.9e-61 yceE S haloacid dehalogenase-like hydrolase
PKGKOOFP_00084 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_00085 2.7e-84 L Transposase IS66 family
PKGKOOFP_00086 3.8e-39 S CAAX protease self-immunity
PKGKOOFP_00087 3.1e-34 S Domain of unknown function (DUF4811)
PKGKOOFP_00088 2.1e-197 lmrB EGP Major facilitator Superfamily
PKGKOOFP_00089 4.2e-32 merR K MerR HTH family regulatory protein
PKGKOOFP_00090 6.7e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PKGKOOFP_00091 3.5e-70 S Protein of unknown function (DUF554)
PKGKOOFP_00092 1.8e-120 G Bacterial extracellular solute-binding protein
PKGKOOFP_00093 3.3e-78 baeR K Bacterial regulatory proteins, luxR family
PKGKOOFP_00094 1.6e-100 baeS T Histidine kinase
PKGKOOFP_00095 3.7e-81 rbsB G sugar-binding domain protein
PKGKOOFP_00096 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PKGKOOFP_00097 2.4e-115 manY G PTS system sorbose-specific iic component
PKGKOOFP_00098 6.1e-147 manN G system, mannose fructose sorbose family IID component
PKGKOOFP_00099 7e-52 manO S Domain of unknown function (DUF956)
PKGKOOFP_00100 2.1e-70 mltD CBM50 M NlpC P60 family protein
PKGKOOFP_00101 8.1e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PKGKOOFP_00102 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKGKOOFP_00103 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
PKGKOOFP_00104 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PKGKOOFP_00105 2.1e-108 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PKGKOOFP_00106 4e-231 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PKGKOOFP_00107 1.3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PKGKOOFP_00108 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PKGKOOFP_00109 1.4e-47 S CRISPR-associated protein (Cas_Csn2)
PKGKOOFP_00110 7.8e-38 K transcriptional regulator PadR family
PKGKOOFP_00111 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
PKGKOOFP_00112 1.2e-15 S Putative adhesin
PKGKOOFP_00113 2.2e-16 pspC KT PspC domain
PKGKOOFP_00114 1.8e-13 S Enterocin A Immunity
PKGKOOFP_00115 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PKGKOOFP_00116 5.7e-261 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
PKGKOOFP_00117 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PKGKOOFP_00118 2.8e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PKGKOOFP_00119 1.2e-119 potB P ABC transporter permease
PKGKOOFP_00120 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
PKGKOOFP_00121 1.3e-159 potD P ABC transporter
PKGKOOFP_00122 3.5e-132 ABC-SBP S ABC transporter
PKGKOOFP_00123 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PKGKOOFP_00124 1e-107 XK27_08845 S ABC transporter, ATP-binding protein
PKGKOOFP_00125 3.7e-66 M ErfK YbiS YcfS YnhG
PKGKOOFP_00126 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PKGKOOFP_00127 6.5e-225 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PKGKOOFP_00128 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PKGKOOFP_00129 1.2e-102 pgm3 G phosphoglycerate mutase
PKGKOOFP_00130 1.5e-57 S CAAX protease self-immunity
PKGKOOFP_00131 1.1e-46 C Flavodoxin
PKGKOOFP_00132 6.9e-58 yphH S Cupin domain
PKGKOOFP_00134 2.9e-29 yphJ 4.1.1.44 S decarboxylase
PKGKOOFP_00135 1.6e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
PKGKOOFP_00136 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
PKGKOOFP_00137 4.4e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PKGKOOFP_00138 1.3e-69 metI P ABC transporter permease
PKGKOOFP_00139 2.6e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PKGKOOFP_00140 3e-84 drgA C nitroreductase
PKGKOOFP_00141 1.1e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PKGKOOFP_00142 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PKGKOOFP_00143 3.4e-170 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PKGKOOFP_00144 3.7e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
PKGKOOFP_00146 3.1e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PKGKOOFP_00147 2.4e-31 metI U ABC transporter permease
PKGKOOFP_00148 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
PKGKOOFP_00149 8.2e-54 S Protein of unknown function (DUF4256)
PKGKOOFP_00151 0.0 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
PKGKOOFP_00152 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PKGKOOFP_00153 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PKGKOOFP_00154 4.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PKGKOOFP_00155 4e-230 lpdA 1.8.1.4 C Dehydrogenase
PKGKOOFP_00156 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
PKGKOOFP_00157 2.7e-55 S Protein of unknown function (DUF975)
PKGKOOFP_00158 2.2e-77 E GDSL-like Lipase/Acylhydrolase family
PKGKOOFP_00159 1.8e-38
PKGKOOFP_00160 4.1e-27 gcvR T Belongs to the UPF0237 family
PKGKOOFP_00161 4.6e-220 XK27_08635 S UPF0210 protein
PKGKOOFP_00162 3.8e-86 fruR K DeoR C terminal sensor domain
PKGKOOFP_00163 2e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PKGKOOFP_00164 3e-284 fruA 2.7.1.202 GT Phosphotransferase System
PKGKOOFP_00165 9.1e-50 cps3F
PKGKOOFP_00166 2.7e-83 S Membrane
PKGKOOFP_00168 1.8e-254 E Amino acid permease
PKGKOOFP_00169 2.2e-225 cadA P P-type ATPase
PKGKOOFP_00170 6.4e-114 degV S EDD domain protein, DegV family
PKGKOOFP_00171 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PKGKOOFP_00172 7.3e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
PKGKOOFP_00173 7.2e-27 ydiI Q Thioesterase superfamily
PKGKOOFP_00174 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PKGKOOFP_00175 2.5e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PKGKOOFP_00176 1e-80 S L,D-transpeptidase catalytic domain
PKGKOOFP_00177 4.4e-165 EGP Major facilitator Superfamily
PKGKOOFP_00178 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
PKGKOOFP_00179 1.2e-226 pipD E Dipeptidase
PKGKOOFP_00180 1.9e-113 L Transposase IS66 family
PKGKOOFP_00181 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_00183 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PKGKOOFP_00184 2.6e-32 ywjH S Protein of unknown function (DUF1634)
PKGKOOFP_00185 3.8e-119 yxaA S membrane transporter protein
PKGKOOFP_00186 7.6e-83 lysR5 K LysR substrate binding domain
PKGKOOFP_00187 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
PKGKOOFP_00188 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PKGKOOFP_00189 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PKGKOOFP_00190 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
PKGKOOFP_00191 5.5e-243 lysP E amino acid
PKGKOOFP_00192 2.1e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PKGKOOFP_00204 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PKGKOOFP_00205 5e-187 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PKGKOOFP_00206 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PKGKOOFP_00207 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PKGKOOFP_00208 3.8e-120 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PKGKOOFP_00210 3.7e-55 ctsR K Belongs to the CtsR family
PKGKOOFP_00211 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PKGKOOFP_00212 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKGKOOFP_00213 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKGKOOFP_00214 1.3e-22 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
PKGKOOFP_00215 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PKGKOOFP_00216 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PKGKOOFP_00217 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PKGKOOFP_00218 1e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PKGKOOFP_00219 9.8e-89 patB 4.4.1.8 E Aminotransferase, class I
PKGKOOFP_00220 4.3e-113 K response regulator
PKGKOOFP_00221 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
PKGKOOFP_00222 1.5e-91 lacX 5.1.3.3 G Aldose 1-epimerase
PKGKOOFP_00223 3.9e-146 G Transporter, major facilitator family protein
PKGKOOFP_00224 2.4e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PKGKOOFP_00225 5.6e-246 yhcA V ABC transporter, ATP-binding protein
PKGKOOFP_00226 2.5e-17 K Bacterial regulatory proteins, tetR family
PKGKOOFP_00227 2.8e-09 K Bacterial regulatory proteins, tetR family
PKGKOOFP_00228 8.9e-224 lmrA V ABC transporter, ATP-binding protein
PKGKOOFP_00229 2.8e-252 yfiC V ABC transporter
PKGKOOFP_00231 2.7e-44 yjcF K protein acetylation
PKGKOOFP_00232 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
PKGKOOFP_00233 1.5e-71 lemA S LemA family
PKGKOOFP_00234 7.8e-115 htpX O Belongs to the peptidase M48B family
PKGKOOFP_00235 6.7e-114 L Transposase IS66 family
PKGKOOFP_00236 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_00239 8.8e-272 helD 3.6.4.12 L DNA helicase
PKGKOOFP_00240 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PKGKOOFP_00241 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PKGKOOFP_00242 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PKGKOOFP_00243 3.2e-75 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
PKGKOOFP_00244 1.6e-104 ybhR V ABC transporter
PKGKOOFP_00245 2.3e-31 K Transcriptional regulator
PKGKOOFP_00246 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
PKGKOOFP_00247 1.3e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PKGKOOFP_00248 7.8e-129
PKGKOOFP_00249 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PKGKOOFP_00250 8.3e-105 tatD L hydrolase, TatD family
PKGKOOFP_00251 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PKGKOOFP_00252 1.7e-133 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PKGKOOFP_00253 1.2e-22 veg S Biofilm formation stimulator VEG
PKGKOOFP_00254 1.3e-133 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
PKGKOOFP_00255 8.2e-47 argR K Regulates arginine biosynthesis genes
PKGKOOFP_00256 1.4e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PKGKOOFP_00257 3.5e-156 amtB P ammonium transporter
PKGKOOFP_00259 2.9e-90 sip L Belongs to the 'phage' integrase family
PKGKOOFP_00260 2.3e-152 S Protein of unknown function (DUF3644)
PKGKOOFP_00262 1e-09
PKGKOOFP_00264 1.2e-49 polC 2.7.7.7 L DNA polymerase III
PKGKOOFP_00265 7.4e-10
PKGKOOFP_00266 6.1e-17 E IrrE N-terminal-like domain
PKGKOOFP_00267 1e-26 K Helix-turn-helix XRE-family like proteins
PKGKOOFP_00268 2e-07
PKGKOOFP_00269 9.1e-66 K Phage regulatory protein
PKGKOOFP_00271 3.9e-31 S Hypothetical protein (DUF2513)
PKGKOOFP_00275 6.7e-18
PKGKOOFP_00276 4.4e-15 K Cro/C1-type HTH DNA-binding domain
PKGKOOFP_00280 2.7e-77 S Siphovirus Gp157
PKGKOOFP_00281 9.8e-242 res L Helicase C-terminal domain protein
PKGKOOFP_00282 7.3e-117 L AAA domain
PKGKOOFP_00283 4e-84
PKGKOOFP_00284 1.4e-139 S Bifunctional DNA primase/polymerase, N-terminal
PKGKOOFP_00285 2.5e-228 S Virulence-associated protein E
PKGKOOFP_00286 8.2e-51 S VRR_NUC
PKGKOOFP_00299 9.3e-18
PKGKOOFP_00301 4.9e-22 L HNH nucleases
PKGKOOFP_00302 4.2e-32 L Phage terminase, small subunit
PKGKOOFP_00303 1.1e-210 S Phage Terminase
PKGKOOFP_00304 1.6e-105 S Phage portal protein, HK97 family
PKGKOOFP_00305 8.9e-72 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
PKGKOOFP_00306 3.3e-94 S Phage capsid family
PKGKOOFP_00307 2.6e-12 L Phage gp6-like head-tail connector protein
PKGKOOFP_00309 2.7e-12 S Bacteriophage HK97-gp10, putative tail-component
PKGKOOFP_00311 2.7e-24 S Phage tail tube protein
PKGKOOFP_00313 1.2e-107 M Phage tail tape measure protein TP901
PKGKOOFP_00314 3.6e-90 S Phage tail protein
PKGKOOFP_00315 2.2e-273 rny D peptidase
PKGKOOFP_00316 1.1e-98 M Prophage endopeptidase tail
PKGKOOFP_00318 9.9e-72 S Domain of unknown function (DUF2479)
PKGKOOFP_00324 3e-128 M Glycosyl hydrolases family 25
PKGKOOFP_00325 2.5e-200 argH 4.3.2.1 E argininosuccinate lyase
PKGKOOFP_00326 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PKGKOOFP_00327 4e-151 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PKGKOOFP_00328 3.1e-128 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKGKOOFP_00329 4.4e-101 pfoS S Phosphotransferase system, EIIC
PKGKOOFP_00330 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PKGKOOFP_00331 6.6e-53 adhR K helix_turn_helix, mercury resistance
PKGKOOFP_00332 5.2e-137 purR 2.4.2.7 F pur operon repressor
PKGKOOFP_00333 4.7e-46 EGP Transmembrane secretion effector
PKGKOOFP_00334 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PKGKOOFP_00335 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PKGKOOFP_00336 1.3e-18 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PKGKOOFP_00337 2.2e-111 dkg S reductase
PKGKOOFP_00338 1.7e-24
PKGKOOFP_00339 6e-79 2.4.2.3 F Phosphorylase superfamily
PKGKOOFP_00340 1.4e-290 ybiT S ABC transporter, ATP-binding protein
PKGKOOFP_00341 6.4e-61 bCE_4747 S Beta-lactamase superfamily domain
PKGKOOFP_00342 1.3e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PKGKOOFP_00343 1.3e-124 S overlaps another CDS with the same product name
PKGKOOFP_00344 2.2e-86 S overlaps another CDS with the same product name
PKGKOOFP_00346 9.6e-55 spoVK O ATPase family associated with various cellular activities (AAA)
PKGKOOFP_00347 7.8e-23
PKGKOOFP_00348 4.2e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
PKGKOOFP_00350 1.5e-72
PKGKOOFP_00351 3.1e-21
PKGKOOFP_00352 1.8e-114 L Transposase IS66 family
PKGKOOFP_00353 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_00355 1.4e-97 ydcZ S Putative inner membrane exporter, YdcZ
PKGKOOFP_00356 1.2e-88 S hydrolase
PKGKOOFP_00357 2.5e-205 ywfO S HD domain protein
PKGKOOFP_00358 9.8e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
PKGKOOFP_00359 1.8e-32 ywiB S Domain of unknown function (DUF1934)
PKGKOOFP_00360 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PKGKOOFP_00361 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PKGKOOFP_00364 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PKGKOOFP_00365 1.2e-188 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PKGKOOFP_00366 3.6e-41 rpmE2 J Ribosomal protein L31
PKGKOOFP_00367 1.3e-61
PKGKOOFP_00368 2.9e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
PKGKOOFP_00370 3e-78 S Cell surface protein
PKGKOOFP_00373 1.6e-180 pbuG S permease
PKGKOOFP_00374 2.1e-83 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PKGKOOFP_00376 2.9e-60 M ErfK YbiS YcfS YnhG
PKGKOOFP_00377 2.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
PKGKOOFP_00378 9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PKGKOOFP_00379 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PKGKOOFP_00380 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PKGKOOFP_00381 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PKGKOOFP_00382 5.4e-13
PKGKOOFP_00383 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
PKGKOOFP_00384 1.6e-90 yunF F Protein of unknown function DUF72
PKGKOOFP_00385 2.5e-155 nrnB S DHHA1 domain
PKGKOOFP_00386 4.8e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PKGKOOFP_00387 2.2e-59
PKGKOOFP_00388 8.6e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
PKGKOOFP_00389 2e-22 S Cytochrome B5
PKGKOOFP_00390 6.8e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
PKGKOOFP_00391 6.9e-70 recX 2.4.1.337 GT4 S Regulatory protein RecX
PKGKOOFP_00392 1.6e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PKGKOOFP_00393 2.6e-97 ygaC J Belongs to the UPF0374 family
PKGKOOFP_00394 4.1e-92 yueF S AI-2E family transporter
PKGKOOFP_00395 2.5e-157 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PKGKOOFP_00396 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PKGKOOFP_00397 7.5e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PKGKOOFP_00398 0.0 lacL 3.2.1.23 G -beta-galactosidase
PKGKOOFP_00399 3e-289 lacS G Transporter
PKGKOOFP_00400 1e-110 galR K Transcriptional regulator
PKGKOOFP_00401 3.4e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PKGKOOFP_00402 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PKGKOOFP_00403 2.4e-201 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PKGKOOFP_00404 0.0 rafA 3.2.1.22 G alpha-galactosidase
PKGKOOFP_00405 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PKGKOOFP_00406 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
PKGKOOFP_00407 0.0 clpE O Belongs to the ClpA ClpB family
PKGKOOFP_00408 1.5e-15
PKGKOOFP_00409 2.2e-36 ptsH G phosphocarrier protein HPR
PKGKOOFP_00410 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PKGKOOFP_00411 3.6e-163 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PKGKOOFP_00412 5.9e-127 cpoA GT4 M Glycosyltransferase, group 1 family protein
PKGKOOFP_00413 6.6e-126 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PKGKOOFP_00414 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
PKGKOOFP_00415 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PKGKOOFP_00424 5.1e-08
PKGKOOFP_00430 2.4e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PKGKOOFP_00431 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PKGKOOFP_00432 1.1e-68 coiA 3.6.4.12 S Competence protein
PKGKOOFP_00433 1.5e-232 pepF E oligoendopeptidase F
PKGKOOFP_00434 1.3e-41 yjbH Q Thioredoxin
PKGKOOFP_00435 5.4e-97 pstS P Phosphate
PKGKOOFP_00436 5.4e-119 pstC P probably responsible for the translocation of the substrate across the membrane
PKGKOOFP_00437 5.1e-122 pstA P Phosphate transport system permease protein PstA
PKGKOOFP_00438 1.3e-113 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PKGKOOFP_00439 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PKGKOOFP_00440 2.7e-56 P Plays a role in the regulation of phosphate uptake
PKGKOOFP_00441 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PKGKOOFP_00442 4.1e-79 S VIT family
PKGKOOFP_00443 9.4e-84 S membrane
PKGKOOFP_00444 1.6e-40 M1-874 K Domain of unknown function (DUF1836)
PKGKOOFP_00445 5.2e-65 hly S protein, hemolysin III
PKGKOOFP_00446 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
PKGKOOFP_00447 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PKGKOOFP_00450 3e-14
PKGKOOFP_00451 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PKGKOOFP_00452 1.3e-158 ccpA K catabolite control protein A
PKGKOOFP_00453 1.1e-41 S VanZ like family
PKGKOOFP_00454 1.5e-119 yebC K Transcriptional regulatory protein
PKGKOOFP_00455 1.3e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PKGKOOFP_00456 8.1e-121 comGA NU Type II IV secretion system protein
PKGKOOFP_00457 5.7e-98 comGB NU type II secretion system
PKGKOOFP_00458 1.2e-27 comGC U competence protein ComGC
PKGKOOFP_00459 1.5e-13
PKGKOOFP_00461 5.5e-11 S Putative Competence protein ComGF
PKGKOOFP_00463 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
PKGKOOFP_00464 1.2e-183 cycA E Amino acid permease
PKGKOOFP_00465 3e-57 S Calcineurin-like phosphoesterase
PKGKOOFP_00466 1.9e-53 yutD S Protein of unknown function (DUF1027)
PKGKOOFP_00467 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PKGKOOFP_00468 7.8e-32 S Protein of unknown function (DUF1461)
PKGKOOFP_00469 5.1e-92 dedA S SNARE associated Golgi protein
PKGKOOFP_00470 7.2e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PKGKOOFP_00471 8.8e-50 yugI 5.3.1.9 J general stress protein
PKGKOOFP_00481 2.1e-07
PKGKOOFP_00491 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PKGKOOFP_00492 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PKGKOOFP_00493 2.4e-192 cycA E Amino acid permease
PKGKOOFP_00494 8.3e-187 ytgP S Polysaccharide biosynthesis protein
PKGKOOFP_00496 1.1e-51 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PKGKOOFP_00497 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PKGKOOFP_00498 3.3e-192 pepV 3.5.1.18 E dipeptidase PepV
PKGKOOFP_00499 1.9e-62 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
PKGKOOFP_00500 1.8e-55 2.1.1.72, 3.1.21.4 L restriction endonuclease
PKGKOOFP_00501 0.0 L Type III restriction enzyme, res subunit
PKGKOOFP_00503 1.1e-35
PKGKOOFP_00504 9.8e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PKGKOOFP_00505 4.2e-61 marR K Transcriptional regulator, MarR family
PKGKOOFP_00506 3.2e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PKGKOOFP_00507 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PKGKOOFP_00508 2.3e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PKGKOOFP_00509 1.9e-98 IQ reductase
PKGKOOFP_00510 6.9e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PKGKOOFP_00511 1e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PKGKOOFP_00512 1.3e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PKGKOOFP_00513 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PKGKOOFP_00514 6.1e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PKGKOOFP_00515 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PKGKOOFP_00516 1.2e-108 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PKGKOOFP_00517 4.3e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PKGKOOFP_00518 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
PKGKOOFP_00519 1.2e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PKGKOOFP_00520 5.7e-119 gla U Major intrinsic protein
PKGKOOFP_00521 5.8e-45 ykuL S CBS domain
PKGKOOFP_00522 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PKGKOOFP_00523 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PKGKOOFP_00524 1.5e-86 ykuT M mechanosensitive ion channel
PKGKOOFP_00526 8.6e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PKGKOOFP_00527 2e-21 yheA S Belongs to the UPF0342 family
PKGKOOFP_00528 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PKGKOOFP_00529 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PKGKOOFP_00531 5.4e-53 hit FG histidine triad
PKGKOOFP_00532 1.3e-94 ecsA V ABC transporter, ATP-binding protein
PKGKOOFP_00533 2.4e-71 ecsB U ABC transporter
PKGKOOFP_00534 1e-97 ytmP 2.7.1.89 M Choline/ethanolamine kinase
PKGKOOFP_00535 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PKGKOOFP_00536 4.4e-44 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PKGKOOFP_00537 1.2e-75 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PKGKOOFP_00538 2.6e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
PKGKOOFP_00539 1.3e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PKGKOOFP_00540 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
PKGKOOFP_00541 5.1e-69 ybhL S Belongs to the BI1 family
PKGKOOFP_00542 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PKGKOOFP_00543 1.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PKGKOOFP_00544 7.8e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PKGKOOFP_00545 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PKGKOOFP_00546 1.4e-78 dnaB L replication initiation and membrane attachment
PKGKOOFP_00547 9.7e-108 dnaI L Primosomal protein DnaI
PKGKOOFP_00548 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PKGKOOFP_00549 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PKGKOOFP_00550 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PKGKOOFP_00551 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PKGKOOFP_00552 4.2e-71 yqeG S HAD phosphatase, family IIIA
PKGKOOFP_00553 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
PKGKOOFP_00554 1e-29 yhbY J RNA-binding protein
PKGKOOFP_00555 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PKGKOOFP_00556 4.7e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PKGKOOFP_00557 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PKGKOOFP_00558 5.5e-82 H Nodulation protein S (NodS)
PKGKOOFP_00559 1.3e-122 ylbM S Belongs to the UPF0348 family
PKGKOOFP_00560 3.5e-57 yceD S Uncharacterized ACR, COG1399
PKGKOOFP_00561 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PKGKOOFP_00562 4e-89 plsC 2.3.1.51 I Acyltransferase
PKGKOOFP_00563 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
PKGKOOFP_00564 1.5e-27 yazA L GIY-YIG catalytic domain protein
PKGKOOFP_00565 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
PKGKOOFP_00566 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PKGKOOFP_00567 6.9e-37
PKGKOOFP_00568 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PKGKOOFP_00569 3.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PKGKOOFP_00570 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PKGKOOFP_00571 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PKGKOOFP_00572 4.6e-108 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PKGKOOFP_00574 3.1e-111 K response regulator
PKGKOOFP_00575 5.6e-166 arlS 2.7.13.3 T Histidine kinase
PKGKOOFP_00576 9.3e-119 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PKGKOOFP_00577 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PKGKOOFP_00578 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PKGKOOFP_00579 2.1e-104
PKGKOOFP_00580 5.5e-117
PKGKOOFP_00581 4.2e-40 dut S dUTPase
PKGKOOFP_00582 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PKGKOOFP_00583 3.7e-46 yqhY S Asp23 family, cell envelope-related function
PKGKOOFP_00584 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PKGKOOFP_00585 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PKGKOOFP_00586 8.9e-147 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PKGKOOFP_00587 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PKGKOOFP_00588 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PKGKOOFP_00589 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PKGKOOFP_00590 6.6e-49 argR K Regulates arginine biosynthesis genes
PKGKOOFP_00591 7.1e-178 recN L May be involved in recombinational repair of damaged DNA
PKGKOOFP_00592 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PKGKOOFP_00593 2.2e-30 ynzC S UPF0291 protein
PKGKOOFP_00594 2.9e-26 yneF S UPF0154 protein
PKGKOOFP_00595 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
PKGKOOFP_00596 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PKGKOOFP_00597 1e-76 yciQ P membrane protein (DUF2207)
PKGKOOFP_00598 5.1e-19 D nuclear chromosome segregation
PKGKOOFP_00599 5.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PKGKOOFP_00600 7.4e-39 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PKGKOOFP_00601 2.2e-69 gluP 3.4.21.105 S Peptidase, S54 family
PKGKOOFP_00602 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
PKGKOOFP_00603 4.7e-158 glk 2.7.1.2 G Glucokinase
PKGKOOFP_00604 2.7e-46 yqhL P Rhodanese-like protein
PKGKOOFP_00605 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
PKGKOOFP_00606 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PKGKOOFP_00607 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
PKGKOOFP_00608 1.3e-45 glnR K Transcriptional regulator
PKGKOOFP_00609 2e-247 glnA 6.3.1.2 E glutamine synthetase
PKGKOOFP_00611 6.7e-114 L Transposase IS66 family
PKGKOOFP_00612 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_00614 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PKGKOOFP_00615 2.7e-48 S Domain of unknown function (DUF956)
PKGKOOFP_00616 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PKGKOOFP_00617 1e-80 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PKGKOOFP_00618 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PKGKOOFP_00619 6.7e-102 cdsA 2.7.7.41 S Belongs to the CDS family
PKGKOOFP_00620 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PKGKOOFP_00621 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PKGKOOFP_00622 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PKGKOOFP_00623 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
PKGKOOFP_00624 4.8e-170 nusA K Participates in both transcription termination and antitermination
PKGKOOFP_00625 1.4e-39 ylxR K Protein of unknown function (DUF448)
PKGKOOFP_00626 6.9e-26 ylxQ J ribosomal protein
PKGKOOFP_00627 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PKGKOOFP_00628 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PKGKOOFP_00629 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PKGKOOFP_00630 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PKGKOOFP_00631 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PKGKOOFP_00632 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PKGKOOFP_00633 1.5e-274 dnaK O Heat shock 70 kDa protein
PKGKOOFP_00634 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PKGKOOFP_00635 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PKGKOOFP_00637 2.1e-205 glnP P ABC transporter
PKGKOOFP_00638 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKGKOOFP_00639 1.5e-31
PKGKOOFP_00640 2e-111 ampC V Beta-lactamase
PKGKOOFP_00641 6e-110 cobQ S glutamine amidotransferase
PKGKOOFP_00642 1.4e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PKGKOOFP_00643 6.8e-86 tdk 2.7.1.21 F thymidine kinase
PKGKOOFP_00644 1.8e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PKGKOOFP_00645 5.3e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PKGKOOFP_00646 1e-134 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PKGKOOFP_00647 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PKGKOOFP_00648 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
PKGKOOFP_00649 1.7e-18 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PKGKOOFP_00650 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PKGKOOFP_00651 7e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PKGKOOFP_00652 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PKGKOOFP_00653 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PKGKOOFP_00654 6.3e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PKGKOOFP_00655 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PKGKOOFP_00656 4.1e-15 ywzB S Protein of unknown function (DUF1146)
PKGKOOFP_00657 5.4e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PKGKOOFP_00658 3.4e-167 mbl D Cell shape determining protein MreB Mrl
PKGKOOFP_00659 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PKGKOOFP_00660 1.3e-13 S Protein of unknown function (DUF2969)
PKGKOOFP_00661 6.1e-187 rodA D Belongs to the SEDS family
PKGKOOFP_00662 2.7e-26 arsC 1.20.4.1 P Belongs to the ArsC family
PKGKOOFP_00663 1.6e-93 2.7.1.89 M Phosphotransferase enzyme family
PKGKOOFP_00664 6.2e-103 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PKGKOOFP_00665 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PKGKOOFP_00666 1.1e-119 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PKGKOOFP_00667 3.2e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PKGKOOFP_00668 4.4e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PKGKOOFP_00669 7.5e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PKGKOOFP_00670 1.9e-90 stp 3.1.3.16 T phosphatase
PKGKOOFP_00671 7.5e-191 KLT serine threonine protein kinase
PKGKOOFP_00672 1.1e-108 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PKGKOOFP_00673 7e-60 thiN 2.7.6.2 H thiamine pyrophosphokinase
PKGKOOFP_00674 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PKGKOOFP_00675 4.5e-53 asp S Asp23 family, cell envelope-related function
PKGKOOFP_00676 3.3e-239 yloV S DAK2 domain fusion protein YloV
PKGKOOFP_00677 5.2e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PKGKOOFP_00678 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PKGKOOFP_00679 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PKGKOOFP_00680 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PKGKOOFP_00681 4.1e-215 smc D Required for chromosome condensation and partitioning
PKGKOOFP_00682 2.3e-144 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PKGKOOFP_00683 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PKGKOOFP_00684 8.5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PKGKOOFP_00685 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PKGKOOFP_00686 1.1e-26 ylqC S Belongs to the UPF0109 family
PKGKOOFP_00687 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PKGKOOFP_00688 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PKGKOOFP_00689 4.4e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
PKGKOOFP_00690 7e-198 yfnA E amino acid
PKGKOOFP_00691 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PKGKOOFP_00692 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
PKGKOOFP_00693 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PKGKOOFP_00694 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PKGKOOFP_00695 2.9e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PKGKOOFP_00696 6.1e-19 S Tetratricopeptide repeat
PKGKOOFP_00697 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PKGKOOFP_00698 1.7e-195 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PKGKOOFP_00699 8.6e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PKGKOOFP_00700 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PKGKOOFP_00701 3.3e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PKGKOOFP_00702 2.5e-22 ykzG S Belongs to the UPF0356 family
PKGKOOFP_00703 5.5e-25
PKGKOOFP_00704 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PKGKOOFP_00705 6.3e-32 1.1.1.27 C L-malate dehydrogenase activity
PKGKOOFP_00706 1.7e-23 yktA S Belongs to the UPF0223 family
PKGKOOFP_00707 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PKGKOOFP_00708 0.0 typA T GTP-binding protein TypA
PKGKOOFP_00709 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PKGKOOFP_00710 7e-115 manY G PTS system
PKGKOOFP_00711 3.3e-148 manN G system, mannose fructose sorbose family IID component
PKGKOOFP_00712 3e-101 ftsW D Belongs to the SEDS family
PKGKOOFP_00713 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PKGKOOFP_00714 1.8e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PKGKOOFP_00715 1.6e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PKGKOOFP_00716 5.3e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PKGKOOFP_00717 4.1e-131 ylbL T Belongs to the peptidase S16 family
PKGKOOFP_00718 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PKGKOOFP_00719 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKGKOOFP_00720 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKGKOOFP_00721 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKGKOOFP_00722 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PKGKOOFP_00723 9e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PKGKOOFP_00724 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PKGKOOFP_00725 1.9e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PKGKOOFP_00726 2.1e-161 purD 6.3.4.13 F Belongs to the GARS family
PKGKOOFP_00727 5.9e-109 S Acyltransferase family
PKGKOOFP_00728 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PKGKOOFP_00729 5e-122 K LysR substrate binding domain
PKGKOOFP_00731 2.2e-20
PKGKOOFP_00732 4.7e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PKGKOOFP_00733 7.5e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
PKGKOOFP_00734 4e-50 comEA L Competence protein ComEA
PKGKOOFP_00735 2e-69 comEB 3.5.4.12 F ComE operon protein 2
PKGKOOFP_00736 1.6e-156 comEC S Competence protein ComEC
PKGKOOFP_00737 7.1e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
PKGKOOFP_00738 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PKGKOOFP_00739 5.6e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PKGKOOFP_00740 2.2e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PKGKOOFP_00741 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PKGKOOFP_00742 4.3e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PKGKOOFP_00743 1.8e-36 ypmB S Protein conserved in bacteria
PKGKOOFP_00744 9e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PKGKOOFP_00745 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PKGKOOFP_00746 5.1e-56 dnaD L DnaD domain protein
PKGKOOFP_00747 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PKGKOOFP_00748 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PKGKOOFP_00749 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PKGKOOFP_00750 3e-94 M transferase activity, transferring glycosyl groups
PKGKOOFP_00751 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
PKGKOOFP_00752 7.6e-100 epsJ1 M Glycosyltransferase like family 2
PKGKOOFP_00755 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PKGKOOFP_00756 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PKGKOOFP_00757 3.1e-56 yqeY S YqeY-like protein
PKGKOOFP_00759 3e-68 xerD L Phage integrase, N-terminal SAM-like domain
PKGKOOFP_00760 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PKGKOOFP_00761 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PKGKOOFP_00762 1.9e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PKGKOOFP_00763 2e-277 yfmR S ABC transporter, ATP-binding protein
PKGKOOFP_00764 3.7e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PKGKOOFP_00765 1.2e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PKGKOOFP_00766 8.7e-74 yvgN C Aldo keto reductase
PKGKOOFP_00767 2.8e-33 yvgN C Aldo keto reductase
PKGKOOFP_00768 2.4e-35 K helix_turn_helix, mercury resistance
PKGKOOFP_00769 4.6e-113 S Aldo keto reductase
PKGKOOFP_00771 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
PKGKOOFP_00772 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PKGKOOFP_00773 8.1e-24 yozE S Belongs to the UPF0346 family
PKGKOOFP_00774 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PKGKOOFP_00775 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PKGKOOFP_00776 1.1e-84 dprA LU DNA protecting protein DprA
PKGKOOFP_00777 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PKGKOOFP_00778 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PKGKOOFP_00779 7.5e-205 G PTS system Galactitol-specific IIC component
PKGKOOFP_00780 2.3e-81 K Bacterial regulatory proteins, tetR family
PKGKOOFP_00781 1.5e-129 yjjC V ATPases associated with a variety of cellular activities
PKGKOOFP_00782 2.3e-202 M Exporter of polyketide antibiotics
PKGKOOFP_00783 1.1e-33 cas6 S Pfam:DUF2276
PKGKOOFP_00784 2.8e-209 csm1 S CRISPR-associated protein Csm1 family
PKGKOOFP_00785 2.8e-33 csm2 L Csm2 Type III-A
PKGKOOFP_00786 3.4e-70 csm3 L RAMP superfamily
PKGKOOFP_00787 4e-66 csm4 L CRISPR-associated RAMP protein, Csm4 family
PKGKOOFP_00788 2.9e-70 csm5 L RAMP superfamily
PKGKOOFP_00789 1.3e-88 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PKGKOOFP_00790 1.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PKGKOOFP_00791 1.1e-71 csm6 S Psort location Cytoplasmic, score
PKGKOOFP_00792 1.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PKGKOOFP_00793 2.7e-35 S Repeat protein
PKGKOOFP_00794 3.8e-276 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PKGKOOFP_00796 1.7e-15
PKGKOOFP_00799 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PKGKOOFP_00800 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PKGKOOFP_00801 9.1e-43 yodB K Transcriptional regulator, HxlR family
PKGKOOFP_00802 1.1e-171 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PKGKOOFP_00803 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PKGKOOFP_00804 5.1e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PKGKOOFP_00805 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
PKGKOOFP_00806 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PKGKOOFP_00807 6.4e-12
PKGKOOFP_00808 2.3e-144 iunH2 3.2.2.1 F nucleoside hydrolase
PKGKOOFP_00809 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
PKGKOOFP_00810 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
PKGKOOFP_00811 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PKGKOOFP_00812 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PKGKOOFP_00813 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PKGKOOFP_00814 3.3e-56 3.1.3.18 J HAD-hyrolase-like
PKGKOOFP_00815 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PKGKOOFP_00816 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PKGKOOFP_00817 2.1e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PKGKOOFP_00818 2.7e-204 pyrP F Permease
PKGKOOFP_00819 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PKGKOOFP_00820 1e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PKGKOOFP_00821 2e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PKGKOOFP_00822 3.9e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PKGKOOFP_00823 9.8e-135 K Transcriptional regulator
PKGKOOFP_00824 1.1e-143 ppaC 3.6.1.1 C inorganic pyrophosphatase
PKGKOOFP_00825 8.6e-115 glcR K DeoR C terminal sensor domain
PKGKOOFP_00826 1.7e-170 patA 2.6.1.1 E Aminotransferase
PKGKOOFP_00827 1.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PKGKOOFP_00829 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PKGKOOFP_00830 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PKGKOOFP_00831 1.4e-36 rnhA 3.1.26.4 L Ribonuclease HI
PKGKOOFP_00832 6.6e-23 S Family of unknown function (DUF5322)
PKGKOOFP_00833 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PKGKOOFP_00834 6.1e-39
PKGKOOFP_00839 2.8e-16 V PFAM secretion protein HlyD family protein
PKGKOOFP_00841 2.5e-149 EGP Sugar (and other) transporter
PKGKOOFP_00842 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
PKGKOOFP_00843 1.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PKGKOOFP_00844 5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PKGKOOFP_00845 3.9e-71 alkD L DNA alkylation repair enzyme
PKGKOOFP_00846 6.4e-136 EG EamA-like transporter family
PKGKOOFP_00847 2.4e-149 S Tetratricopeptide repeat protein
PKGKOOFP_00848 9.1e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
PKGKOOFP_00849 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PKGKOOFP_00850 7e-127 corA P CorA-like Mg2+ transporter protein
PKGKOOFP_00851 1.4e-160 nhaC C Na H antiporter NhaC
PKGKOOFP_00852 7.2e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PKGKOOFP_00853 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PKGKOOFP_00855 1.2e-91 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PKGKOOFP_00856 1.7e-159 iscS 2.8.1.7 E Aminotransferase class V
PKGKOOFP_00857 3.7e-41 XK27_04120 S Putative amino acid metabolism
PKGKOOFP_00858 1.4e-201 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PKGKOOFP_00859 5.9e-55 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PKGKOOFP_00860 3.1e-289 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PKGKOOFP_00861 4.3e-15 S Protein of unknown function (DUF2929)
PKGKOOFP_00862 0.0 dnaE 2.7.7.7 L DNA polymerase
PKGKOOFP_00863 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PKGKOOFP_00864 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PKGKOOFP_00866 1e-39 ypaA S Protein of unknown function (DUF1304)
PKGKOOFP_00867 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PKGKOOFP_00868 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PKGKOOFP_00869 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PKGKOOFP_00870 1.9e-202 FbpA K Fibronectin-binding protein
PKGKOOFP_00871 3.1e-40 K Transcriptional regulator
PKGKOOFP_00872 6.3e-117 degV S EDD domain protein, DegV family
PKGKOOFP_00873 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
PKGKOOFP_00874 2.7e-39 6.3.3.2 S ASCH
PKGKOOFP_00875 1.7e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PKGKOOFP_00876 1.1e-78 yjjH S Calcineurin-like phosphoesterase
PKGKOOFP_00877 1.2e-91 EG EamA-like transporter family
PKGKOOFP_00878 6.7e-114 L Transposase IS66 family
PKGKOOFP_00879 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_00881 1.1e-84 natB CP ABC-type Na efflux pump, permease component
PKGKOOFP_00882 6.9e-111 natA S Domain of unknown function (DUF4162)
PKGKOOFP_00883 8.2e-23 K Acetyltransferase (GNAT) domain
PKGKOOFP_00885 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PKGKOOFP_00886 1.3e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PKGKOOFP_00887 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
PKGKOOFP_00888 3.7e-59 arsC 1.20.4.1 T Low molecular weight phosphatase family
PKGKOOFP_00889 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PKGKOOFP_00890 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKGKOOFP_00891 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
PKGKOOFP_00892 1.3e-218 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKGKOOFP_00893 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
PKGKOOFP_00894 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
PKGKOOFP_00895 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PKGKOOFP_00896 2.8e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PKGKOOFP_00897 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PKGKOOFP_00898 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
PKGKOOFP_00899 2.6e-83 lytH 3.5.1.28 M Ami_3
PKGKOOFP_00900 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PKGKOOFP_00901 7.7e-12 M Lysin motif
PKGKOOFP_00902 1e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PKGKOOFP_00903 2.9e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
PKGKOOFP_00904 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
PKGKOOFP_00905 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
PKGKOOFP_00906 6.4e-121 ica2 GT2 M Glycosyl transferase family group 2
PKGKOOFP_00907 8.3e-44
PKGKOOFP_00908 5.5e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PKGKOOFP_00910 1.8e-185 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PKGKOOFP_00911 1.5e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PKGKOOFP_00912 3.3e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PKGKOOFP_00913 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PKGKOOFP_00914 8.9e-96 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
PKGKOOFP_00915 6.3e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKGKOOFP_00916 2e-62 3.1.21.3 V Type I restriction modification DNA specificity domain
PKGKOOFP_00917 3.3e-72 3.1.21.3 V Type I restriction modification DNA specificity domain
PKGKOOFP_00918 2.8e-131 L Belongs to the 'phage' integrase family
PKGKOOFP_00919 6.1e-99 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PKGKOOFP_00920 2.7e-211 hsdM 2.1.1.72 V type I restriction-modification system
PKGKOOFP_00921 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PKGKOOFP_00923 3.9e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
PKGKOOFP_00924 5.7e-57 3.6.1.27 I Acid phosphatase homologues
PKGKOOFP_00925 1.9e-67 maa 2.3.1.79 S Maltose acetyltransferase
PKGKOOFP_00926 7e-72 2.3.1.178 M GNAT acetyltransferase
PKGKOOFP_00928 1.4e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
PKGKOOFP_00929 1.5e-63 ypsA S Belongs to the UPF0398 family
PKGKOOFP_00930 1.3e-188 nhaC C Na H antiporter NhaC
PKGKOOFP_00931 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PKGKOOFP_00932 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PKGKOOFP_00933 7.3e-113 xerD D recombinase XerD
PKGKOOFP_00934 1.1e-124 cvfB S S1 domain
PKGKOOFP_00935 1.6e-50 yeaL S Protein of unknown function (DUF441)
PKGKOOFP_00936 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PKGKOOFP_00937 8.4e-99 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PKGKOOFP_00938 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PKGKOOFP_00939 5.9e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PKGKOOFP_00940 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PKGKOOFP_00941 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PKGKOOFP_00942 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PKGKOOFP_00943 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PKGKOOFP_00944 3.9e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PKGKOOFP_00945 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PKGKOOFP_00946 3.1e-71
PKGKOOFP_00948 3.7e-12
PKGKOOFP_00949 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PKGKOOFP_00950 1e-27 ysxB J Cysteine protease Prp
PKGKOOFP_00951 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
PKGKOOFP_00955 9.8e-09 S Protein of unknown function (DUF2922)
PKGKOOFP_00957 1.3e-16 K DNA-templated transcription, initiation
PKGKOOFP_00959 8.1e-65 H Methyltransferase domain
PKGKOOFP_00960 1e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
PKGKOOFP_00961 1.9e-41 wecD M Acetyltransferase (GNAT) family
PKGKOOFP_00963 1.8e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
PKGKOOFP_00964 3.4e-41 S Protein of unknown function (DUF1211)
PKGKOOFP_00966 6.6e-86 1.1.1.1 C Zinc-binding dehydrogenase
PKGKOOFP_00967 2.2e-32 S CHY zinc finger
PKGKOOFP_00968 9.5e-40 K Transcriptional regulator
PKGKOOFP_00969 1.2e-83 qorB 1.6.5.2 GM NmrA-like family
PKGKOOFP_00971 4.5e-64 M Glycosyl transferases group 1
PKGKOOFP_00972 2.6e-180 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PKGKOOFP_00973 1.4e-145 lspL 5.1.3.6 GM RmlD substrate binding domain
PKGKOOFP_00974 1.1e-105 cps2I S Psort location CytoplasmicMembrane, score
PKGKOOFP_00975 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
PKGKOOFP_00976 2.2e-114 S Glycosyltransferase WbsX
PKGKOOFP_00977 2.1e-08 wzy S EpsG family
PKGKOOFP_00978 1.7e-56 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
PKGKOOFP_00979 1.1e-73 M Glycosyltransferase Family 4
PKGKOOFP_00980 3.3e-52 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
PKGKOOFP_00981 2.9e-24 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
PKGKOOFP_00982 6.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
PKGKOOFP_00983 3.9e-124 2.4.1.52 GT4 M Glycosyl transferases group 1
PKGKOOFP_00984 6.5e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
PKGKOOFP_00985 3.1e-76 epsL M Bacterial sugar transferase
PKGKOOFP_00986 3.4e-166 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
PKGKOOFP_00987 2.2e-220 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
PKGKOOFP_00988 4.6e-65 cpsD D AAA domain
PKGKOOFP_00989 4e-48 cps4C M Chain length determinant protein
PKGKOOFP_00991 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_00993 3e-95 L Transposase IS66 family
PKGKOOFP_00994 1e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PKGKOOFP_00995 3.8e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PKGKOOFP_00996 8.1e-81
PKGKOOFP_00997 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PKGKOOFP_00998 1e-113 yitU 3.1.3.104 S hydrolase
PKGKOOFP_00999 1.2e-59 speG J Acetyltransferase (GNAT) domain
PKGKOOFP_01000 8.8e-192 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PKGKOOFP_01001 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PKGKOOFP_01002 1.3e-204 pipD E Dipeptidase
PKGKOOFP_01003 2.8e-43
PKGKOOFP_01004 1.7e-63 K helix_turn_helix, arabinose operon control protein
PKGKOOFP_01005 2e-53 S Membrane
PKGKOOFP_01006 0.0 rafA 3.2.1.22 G alpha-galactosidase
PKGKOOFP_01008 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_01009 6.7e-114 L Transposase IS66 family
PKGKOOFP_01010 3.6e-60 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
PKGKOOFP_01011 3.8e-307 L Helicase C-terminal domain protein
PKGKOOFP_01012 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
PKGKOOFP_01013 1.5e-95 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
PKGKOOFP_01014 2.2e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
PKGKOOFP_01015 1.4e-113 2.7.7.65 T diguanylate cyclase activity
PKGKOOFP_01016 0.0 ydaN S Bacterial cellulose synthase subunit
PKGKOOFP_01017 6.9e-202 ydaM M Glycosyl transferase family group 2
PKGKOOFP_01018 8.4e-205 S Protein conserved in bacteria
PKGKOOFP_01019 1.4e-182
PKGKOOFP_01020 2.8e-127 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
PKGKOOFP_01021 8.1e-43 2.7.7.65 T GGDEF domain
PKGKOOFP_01022 7.3e-146 pbuO_1 S Permease family
PKGKOOFP_01023 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
PKGKOOFP_01024 9.7e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PKGKOOFP_01025 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PKGKOOFP_01026 2.6e-218 cydD CO ABC transporter transmembrane region
PKGKOOFP_01027 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PKGKOOFP_01028 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PKGKOOFP_01029 2.1e-194 cydA 1.10.3.14 C ubiquinol oxidase
PKGKOOFP_01030 1.5e-159 asnA 6.3.1.1 F aspartate--ammonia ligase
PKGKOOFP_01031 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
PKGKOOFP_01032 5e-19 glpE P Rhodanese Homology Domain
PKGKOOFP_01033 4.2e-49 lytE M LysM domain protein
PKGKOOFP_01034 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
PKGKOOFP_01035 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
PKGKOOFP_01037 4.4e-74 draG O ADP-ribosylglycohydrolase
PKGKOOFP_01038 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PKGKOOFP_01039 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PKGKOOFP_01040 8.6e-62 divIVA D DivIVA domain protein
PKGKOOFP_01041 1.7e-81 ylmH S S4 domain protein
PKGKOOFP_01042 3e-19 yggT S YGGT family
PKGKOOFP_01043 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PKGKOOFP_01044 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PKGKOOFP_01045 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PKGKOOFP_01046 1.6e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PKGKOOFP_01047 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PKGKOOFP_01048 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PKGKOOFP_01049 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PKGKOOFP_01050 2.4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
PKGKOOFP_01051 2.5e-11 ftsL D cell division protein FtsL
PKGKOOFP_01052 6.7e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PKGKOOFP_01053 5.2e-64 mraZ K Belongs to the MraZ family
PKGKOOFP_01054 2.2e-07 S Protein of unknown function (DUF3397)
PKGKOOFP_01055 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
PKGKOOFP_01057 9.8e-100 D Alpha beta
PKGKOOFP_01058 3.7e-109 aatB ET ABC transporter substrate-binding protein
PKGKOOFP_01059 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKGKOOFP_01060 2.5e-94 glnP P ABC transporter permease
PKGKOOFP_01061 1.8e-126 minD D Belongs to the ParA family
PKGKOOFP_01062 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PKGKOOFP_01063 5.8e-54 mreD M rod shape-determining protein MreD
PKGKOOFP_01064 2.1e-88 mreC M Involved in formation and maintenance of cell shape
PKGKOOFP_01065 3.6e-156 mreB D cell shape determining protein MreB
PKGKOOFP_01066 4.5e-21 K Cold shock
PKGKOOFP_01067 1.1e-79 radC L DNA repair protein
PKGKOOFP_01068 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PKGKOOFP_01069 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PKGKOOFP_01070 3.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PKGKOOFP_01071 3.8e-162 iscS2 2.8.1.7 E Aminotransferase class V
PKGKOOFP_01072 4.4e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PKGKOOFP_01073 3.5e-55 ytsP 1.8.4.14 T GAF domain-containing protein
PKGKOOFP_01074 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PKGKOOFP_01075 2e-24 yueI S Protein of unknown function (DUF1694)
PKGKOOFP_01076 5.2e-189 rarA L recombination factor protein RarA
PKGKOOFP_01078 3.2e-73 usp6 T universal stress protein
PKGKOOFP_01079 3.8e-54 tag 3.2.2.20 L glycosylase
PKGKOOFP_01080 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PKGKOOFP_01081 3.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PKGKOOFP_01083 4.6e-71 yviA S Protein of unknown function (DUF421)
PKGKOOFP_01084 4.3e-14 S Protein of unknown function (DUF3290)
PKGKOOFP_01086 2.3e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
PKGKOOFP_01087 1.2e-296 S membrane
PKGKOOFP_01088 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PKGKOOFP_01089 1.2e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
PKGKOOFP_01090 3.2e-99 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
PKGKOOFP_01091 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PKGKOOFP_01093 6.3e-17
PKGKOOFP_01094 5.6e-200 oatA I Acyltransferase
PKGKOOFP_01095 6.3e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PKGKOOFP_01096 1.9e-306 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PKGKOOFP_01097 2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKGKOOFP_01100 1.5e-41 S Phosphoesterase
PKGKOOFP_01101 5e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PKGKOOFP_01102 1.1e-60 yslB S Protein of unknown function (DUF2507)
PKGKOOFP_01103 9.9e-41 trxA O Belongs to the thioredoxin family
PKGKOOFP_01104 2.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PKGKOOFP_01105 7.5e-15 cvpA S Colicin V production protein
PKGKOOFP_01106 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PKGKOOFP_01107 1.9e-33 yrzB S Belongs to the UPF0473 family
PKGKOOFP_01108 1e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PKGKOOFP_01109 2.1e-36 yrzL S Belongs to the UPF0297 family
PKGKOOFP_01110 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PKGKOOFP_01111 1.5e-186 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PKGKOOFP_01112 4.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PKGKOOFP_01113 7.5e-13
PKGKOOFP_01114 8e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PKGKOOFP_01115 1.3e-67 yrjD S LUD domain
PKGKOOFP_01116 3.6e-245 lutB C 4Fe-4S dicluster domain
PKGKOOFP_01117 6.9e-117 lutA C Cysteine-rich domain
PKGKOOFP_01118 2e-208 yfnA E Amino Acid
PKGKOOFP_01120 4.8e-60 uspA T universal stress protein
PKGKOOFP_01122 1.4e-12 yajC U Preprotein translocase
PKGKOOFP_01123 2.3e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PKGKOOFP_01124 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PKGKOOFP_01125 2.8e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PKGKOOFP_01126 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PKGKOOFP_01127 1.3e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PKGKOOFP_01128 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PKGKOOFP_01129 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
PKGKOOFP_01130 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PKGKOOFP_01131 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PKGKOOFP_01132 1.5e-63 ymfM S Helix-turn-helix domain
PKGKOOFP_01133 1.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
PKGKOOFP_01134 6.4e-150 ymfH S Peptidase M16
PKGKOOFP_01135 1.3e-107 ymfF S Peptidase M16 inactive domain protein
PKGKOOFP_01136 4.5e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
PKGKOOFP_01137 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PKGKOOFP_01138 1.3e-98 rrmA 2.1.1.187 H Methyltransferase
PKGKOOFP_01139 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
PKGKOOFP_01140 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PKGKOOFP_01141 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PKGKOOFP_01142 3.2e-21 cutC P Participates in the control of copper homeostasis
PKGKOOFP_01143 2e-130 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PKGKOOFP_01144 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PKGKOOFP_01145 4.4e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PKGKOOFP_01146 5.3e-68 ybbR S YbbR-like protein
PKGKOOFP_01147 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PKGKOOFP_01148 2.4e-71 S Protein of unknown function (DUF1361)
PKGKOOFP_01149 4.6e-115 murB 1.3.1.98 M Cell wall formation
PKGKOOFP_01150 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
PKGKOOFP_01151 2.7e-55 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PKGKOOFP_01152 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PKGKOOFP_01153 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PKGKOOFP_01154 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
PKGKOOFP_01155 4.1e-42 yxjI
PKGKOOFP_01156 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PKGKOOFP_01157 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PKGKOOFP_01158 2.8e-19 secG U Preprotein translocase
PKGKOOFP_01159 9.2e-180 clcA P chloride
PKGKOOFP_01160 7.4e-145 lmrP E Major Facilitator Superfamily
PKGKOOFP_01161 1.8e-169 T PhoQ Sensor
PKGKOOFP_01162 1.9e-103 K response regulator
PKGKOOFP_01163 4.6e-130 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PKGKOOFP_01164 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PKGKOOFP_01165 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PKGKOOFP_01166 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PKGKOOFP_01167 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PKGKOOFP_01168 6.4e-137 cggR K Putative sugar-binding domain
PKGKOOFP_01170 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PKGKOOFP_01171 1.8e-149 whiA K May be required for sporulation
PKGKOOFP_01172 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PKGKOOFP_01173 7.5e-126 rapZ S Displays ATPase and GTPase activities
PKGKOOFP_01174 6.7e-114 L Transposase IS66 family
PKGKOOFP_01175 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_01177 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
PKGKOOFP_01178 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PKGKOOFP_01179 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PKGKOOFP_01180 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PKGKOOFP_01181 1.8e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PKGKOOFP_01182 1.9e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PKGKOOFP_01183 9.6e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PKGKOOFP_01184 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PKGKOOFP_01185 3.2e-08 KT PspC domain protein
PKGKOOFP_01186 6.5e-84 phoR 2.7.13.3 T Histidine kinase
PKGKOOFP_01187 4.6e-86 K response regulator
PKGKOOFP_01188 4.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
PKGKOOFP_01189 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PKGKOOFP_01190 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PKGKOOFP_01191 1.7e-96 yeaN P Major Facilitator Superfamily
PKGKOOFP_01192 1.7e-80 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PKGKOOFP_01193 1e-45 comFC S Competence protein
PKGKOOFP_01194 4.2e-128 comFA L Helicase C-terminal domain protein
PKGKOOFP_01195 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
PKGKOOFP_01196 4.1e-296 ydaO E amino acid
PKGKOOFP_01197 1.3e-268 aha1 P COG COG0474 Cation transport ATPase
PKGKOOFP_01198 1.8e-114 L Transposase IS66 family
PKGKOOFP_01199 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_01201 3.7e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PKGKOOFP_01202 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PKGKOOFP_01203 5.3e-33 S CAAX protease self-immunity
PKGKOOFP_01204 8.2e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PKGKOOFP_01205 1.9e-254 uup S ABC transporter, ATP-binding protein
PKGKOOFP_01206 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PKGKOOFP_01207 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PKGKOOFP_01208 2.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PKGKOOFP_01209 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
PKGKOOFP_01210 2.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
PKGKOOFP_01211 2.4e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PKGKOOFP_01212 1.4e-40 yabA L Involved in initiation control of chromosome replication
PKGKOOFP_01213 2.3e-83 holB 2.7.7.7 L DNA polymerase III
PKGKOOFP_01214 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PKGKOOFP_01215 1.3e-28 yaaL S Protein of unknown function (DUF2508)
PKGKOOFP_01216 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PKGKOOFP_01217 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PKGKOOFP_01218 7.9e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PKGKOOFP_01219 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PKGKOOFP_01220 2.4e-75 rsmC 2.1.1.172 J Methyltransferase
PKGKOOFP_01221 2.7e-27 nrdH O Glutaredoxin
PKGKOOFP_01222 4.8e-45 nrdI F NrdI Flavodoxin like
PKGKOOFP_01223 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKGKOOFP_01224 5.2e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKGKOOFP_01225 2.7e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PKGKOOFP_01226 4.7e-55
PKGKOOFP_01227 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PKGKOOFP_01228 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PKGKOOFP_01229 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PKGKOOFP_01230 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PKGKOOFP_01231 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
PKGKOOFP_01232 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PKGKOOFP_01233 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PKGKOOFP_01234 7e-71 yacP S YacP-like NYN domain
PKGKOOFP_01235 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PKGKOOFP_01236 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PKGKOOFP_01237 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PKGKOOFP_01238 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PKGKOOFP_01239 8.2e-154 yacL S domain protein
PKGKOOFP_01240 2.1e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PKGKOOFP_01241 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PKGKOOFP_01242 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
PKGKOOFP_01243 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
PKGKOOFP_01244 1e-33 S Enterocin A Immunity
PKGKOOFP_01245 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PKGKOOFP_01246 5.9e-129 mleP2 S Sodium Bile acid symporter family
PKGKOOFP_01247 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PKGKOOFP_01249 3.6e-44 ydcK S Belongs to the SprT family
PKGKOOFP_01250 1.2e-249 yhgF K Tex-like protein N-terminal domain protein
PKGKOOFP_01251 2.3e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PKGKOOFP_01252 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PKGKOOFP_01253 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PKGKOOFP_01254 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
PKGKOOFP_01255 6.6e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PKGKOOFP_01257 1.1e-07
PKGKOOFP_01258 1.6e-197 dtpT U amino acid peptide transporter
PKGKOOFP_01259 1.9e-92 yihY S Belongs to the UPF0761 family
PKGKOOFP_01260 4.7e-12 mltD CBM50 M Lysin motif
PKGKOOFP_01261 3e-151 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PKGKOOFP_01262 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
PKGKOOFP_01263 5.1e-54 fld C Flavodoxin
PKGKOOFP_01264 8.7e-53 gtcA S Teichoic acid glycosylation protein
PKGKOOFP_01265 0.0 S Bacterial membrane protein YfhO
PKGKOOFP_01266 6.8e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
PKGKOOFP_01267 1.7e-122 S Sulfite exporter TauE/SafE
PKGKOOFP_01268 1.1e-70 K Sugar-specific transcriptional regulator TrmB
PKGKOOFP_01269 1.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PKGKOOFP_01270 3.9e-181 pepS E Thermophilic metalloprotease (M29)
PKGKOOFP_01271 1.8e-266 E Amino acid permease
PKGKOOFP_01272 2e-83 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PKGKOOFP_01273 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PKGKOOFP_01274 2.6e-79 galM 5.1.3.3 G Aldose 1-epimerase
PKGKOOFP_01275 1.1e-213 malT G Transporter, major facilitator family protein
PKGKOOFP_01276 4.2e-101 malR K Transcriptional regulator, LacI family
PKGKOOFP_01277 1.9e-278 kup P Transport of potassium into the cell
PKGKOOFP_01279 2e-20 S Domain of unknown function (DUF3284)
PKGKOOFP_01280 5.2e-160 yfmL L DEAD DEAH box helicase
PKGKOOFP_01281 7e-128 mocA S Oxidoreductase
PKGKOOFP_01282 2e-24 S Domain of unknown function (DUF4828)
PKGKOOFP_01283 1.8e-174 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
PKGKOOFP_01284 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PKGKOOFP_01285 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
PKGKOOFP_01286 1.4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
PKGKOOFP_01287 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PKGKOOFP_01288 2.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PKGKOOFP_01289 8.5e-222 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PKGKOOFP_01290 1.1e-41 O ADP-ribosylglycohydrolase
PKGKOOFP_01291 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
PKGKOOFP_01292 2.9e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PKGKOOFP_01293 1.3e-34 K GNAT family
PKGKOOFP_01294 1.7e-40
PKGKOOFP_01296 5.5e-160 mgtE P Acts as a magnesium transporter
PKGKOOFP_01297 1.9e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PKGKOOFP_01298 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PKGKOOFP_01299 5.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
PKGKOOFP_01300 3.9e-258 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PKGKOOFP_01301 9.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PKGKOOFP_01302 9.7e-194 pbuX F xanthine permease
PKGKOOFP_01303 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PKGKOOFP_01304 3.1e-60 acmC 3.2.1.96 NU mannosyl-glycoprotein
PKGKOOFP_01305 9.4e-64 S ECF transporter, substrate-specific component
PKGKOOFP_01306 2.8e-126 mleP S Sodium Bile acid symporter family
PKGKOOFP_01307 4.4e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PKGKOOFP_01308 6.2e-72 mleR K LysR family
PKGKOOFP_01309 1.1e-56 K transcriptional
PKGKOOFP_01310 1.5e-41 K Bacterial regulatory proteins, tetR family
PKGKOOFP_01311 6.1e-60 T Belongs to the universal stress protein A family
PKGKOOFP_01312 1.2e-44 K Copper transport repressor CopY TcrY
PKGKOOFP_01313 1.2e-230 3.2.1.18 GH33 M Rib/alpha-like repeat
PKGKOOFP_01315 1.9e-95 ypuA S Protein of unknown function (DUF1002)
PKGKOOFP_01316 2.7e-58 dedA 3.1.3.1 S SNARE associated Golgi protein
PKGKOOFP_01317 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PKGKOOFP_01318 2.6e-18 yncA 2.3.1.79 S Maltose acetyltransferase
PKGKOOFP_01319 1.5e-205 yflS P Sodium:sulfate symporter transmembrane region
PKGKOOFP_01320 7.2e-200 frdC 1.3.5.4 C FAD binding domain
PKGKOOFP_01321 1.9e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PKGKOOFP_01322 2e-14 ybaN S Protein of unknown function (DUF454)
PKGKOOFP_01323 6.3e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PKGKOOFP_01324 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PKGKOOFP_01325 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PKGKOOFP_01326 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PKGKOOFP_01327 1.1e-71 ywlG S Belongs to the UPF0340 family
PKGKOOFP_01328 3.3e-158 C Oxidoreductase
PKGKOOFP_01329 8.6e-176 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
PKGKOOFP_01331 2.2e-146 3.6.4.12 L UvrD/REP helicase N-terminal domain
PKGKOOFP_01332 4.8e-122 L AAA ATPase domain
PKGKOOFP_01334 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_01335 6.7e-114 L Transposase IS66 family
PKGKOOFP_01336 4e-26 L AAA ATPase domain
PKGKOOFP_01337 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
PKGKOOFP_01338 1.3e-75 3.1.21.3 V Type I restriction modification DNA specificity domain
PKGKOOFP_01339 0.0 2.1.1.72 V type I restriction-modification system
PKGKOOFP_01340 3.9e-19
PKGKOOFP_01341 3.7e-122 L Mrr N-terminal domain
PKGKOOFP_01342 2.6e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PKGKOOFP_01343 3.4e-146 yegS 2.7.1.107 G Lipid kinase
PKGKOOFP_01344 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PKGKOOFP_01345 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PKGKOOFP_01346 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PKGKOOFP_01347 7.1e-161 camS S sex pheromone
PKGKOOFP_01348 5.1e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PKGKOOFP_01349 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PKGKOOFP_01351 3.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PKGKOOFP_01355 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PKGKOOFP_01356 6.1e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PKGKOOFP_01357 2.4e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PKGKOOFP_01358 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PKGKOOFP_01359 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PKGKOOFP_01360 4.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PKGKOOFP_01361 1.1e-40 yabR J RNA binding
PKGKOOFP_01362 1e-21 divIC D Septum formation initiator
PKGKOOFP_01363 3.6e-31 yabO J S4 domain protein
PKGKOOFP_01364 7.3e-140 yabM S Polysaccharide biosynthesis protein
PKGKOOFP_01365 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PKGKOOFP_01366 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PKGKOOFP_01367 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PKGKOOFP_01368 2.5e-86 S (CBS) domain
PKGKOOFP_01369 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PKGKOOFP_01370 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PKGKOOFP_01371 7.2e-53 perR P Belongs to the Fur family
PKGKOOFP_01372 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
PKGKOOFP_01373 1.7e-95 sbcC L Putative exonuclease SbcCD, C subunit
PKGKOOFP_01374 3.7e-114 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PKGKOOFP_01375 2.1e-36 M LysM domain protein
PKGKOOFP_01376 1.9e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PKGKOOFP_01377 1.1e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PKGKOOFP_01378 2.7e-35 ygfC K Bacterial regulatory proteins, tetR family
PKGKOOFP_01379 7.7e-101 hrtB V ABC transporter permease
PKGKOOFP_01380 2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PKGKOOFP_01381 4.7e-68 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PKGKOOFP_01382 0.0 helD 3.6.4.12 L DNA helicase
PKGKOOFP_01383 8.9e-246 yjbQ P TrkA C-terminal domain protein
PKGKOOFP_01384 2.6e-23
PKGKOOFP_01385 1.2e-59 rpsI J Belongs to the universal ribosomal protein uS9 family
PKGKOOFP_01386 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PKGKOOFP_01387 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PKGKOOFP_01388 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKGKOOFP_01389 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKGKOOFP_01390 6.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKGKOOFP_01391 4.8e-53 rplQ J Ribosomal protein L17
PKGKOOFP_01392 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKGKOOFP_01393 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PKGKOOFP_01394 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PKGKOOFP_01395 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PKGKOOFP_01396 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PKGKOOFP_01397 2.9e-106 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PKGKOOFP_01398 9.7e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PKGKOOFP_01399 1e-67 rplO J Binds to the 23S rRNA
PKGKOOFP_01400 2.1e-22 rpmD J Ribosomal protein L30
PKGKOOFP_01401 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PKGKOOFP_01402 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PKGKOOFP_01403 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PKGKOOFP_01404 1.3e-64 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PKGKOOFP_01405 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PKGKOOFP_01406 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PKGKOOFP_01407 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PKGKOOFP_01408 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PKGKOOFP_01409 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PKGKOOFP_01410 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
PKGKOOFP_01411 1.8e-72 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PKGKOOFP_01412 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PKGKOOFP_01413 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PKGKOOFP_01414 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PKGKOOFP_01415 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PKGKOOFP_01416 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PKGKOOFP_01417 1e-100 rplD J Forms part of the polypeptide exit tunnel
PKGKOOFP_01418 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PKGKOOFP_01419 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PKGKOOFP_01420 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PKGKOOFP_01421 6.5e-79 K rpiR family
PKGKOOFP_01422 1.4e-52 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PKGKOOFP_01423 3.2e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
PKGKOOFP_01424 6.5e-21 K Acetyltransferase (GNAT) domain
PKGKOOFP_01425 9e-184 steT E amino acid
PKGKOOFP_01426 9.6e-78 glnP P ABC transporter permease
PKGKOOFP_01427 1.2e-85 gluC P ABC transporter permease
PKGKOOFP_01428 1.9e-99 glnH ET ABC transporter
PKGKOOFP_01429 6.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKGKOOFP_01430 1.3e-09
PKGKOOFP_01431 5e-98
PKGKOOFP_01432 3e-12 3.2.1.14 GH18
PKGKOOFP_01433 3.2e-53 zur P Belongs to the Fur family
PKGKOOFP_01434 3.7e-212 yfnA E Amino Acid
PKGKOOFP_01435 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PKGKOOFP_01436 0.0 L Helicase C-terminal domain protein
PKGKOOFP_01437 2e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
PKGKOOFP_01438 4.6e-180 yhdP S Transporter associated domain
PKGKOOFP_01439 3.7e-26
PKGKOOFP_01440 2.4e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PKGKOOFP_01441 9.6e-132 bacI V MacB-like periplasmic core domain
PKGKOOFP_01442 4.3e-97 V ABC transporter
PKGKOOFP_01443 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PKGKOOFP_01444 5.2e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
PKGKOOFP_01445 3.6e-140 V MatE
PKGKOOFP_01446 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PKGKOOFP_01447 5e-87 S Alpha beta hydrolase
PKGKOOFP_01448 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PKGKOOFP_01449 7.3e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PKGKOOFP_01450 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
PKGKOOFP_01451 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
PKGKOOFP_01452 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
PKGKOOFP_01453 4.3e-54 queT S QueT transporter
PKGKOOFP_01455 1.5e-65 degV S Uncharacterised protein, DegV family COG1307
PKGKOOFP_01456 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PKGKOOFP_01457 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PKGKOOFP_01458 1.9e-34 trxA O Belongs to the thioredoxin family
PKGKOOFP_01459 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
PKGKOOFP_01460 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PKGKOOFP_01461 1.3e-49 S Threonine/Serine exporter, ThrE
PKGKOOFP_01462 4.3e-82 thrE S Putative threonine/serine exporter
PKGKOOFP_01463 3.1e-27 cspC K Cold shock protein
PKGKOOFP_01464 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
PKGKOOFP_01465 1.5e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PKGKOOFP_01466 5.4e-23
PKGKOOFP_01467 1.2e-58 3.6.1.27 I phosphatase
PKGKOOFP_01468 7e-25
PKGKOOFP_01469 1.6e-66 I alpha/beta hydrolase fold
PKGKOOFP_01470 1.3e-38 azlD S branched-chain amino acid
PKGKOOFP_01471 1.9e-104 azlC E AzlC protein
PKGKOOFP_01472 9.1e-18
PKGKOOFP_01473 1.7e-119 xth 3.1.11.2 L exodeoxyribonuclease III
PKGKOOFP_01474 6.6e-119 V domain protein
PKGKOOFP_01475 8e-17
PKGKOOFP_01478 3.2e-09 S zinc-ribbon domain
PKGKOOFP_01480 8.9e-11 S Mor transcription activator family
PKGKOOFP_01481 6e-60 yfjR K WYL domain
PKGKOOFP_01482 6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PKGKOOFP_01483 7.6e-174 malY 4.4.1.8 E Aminotransferase, class I
PKGKOOFP_01484 6.9e-118 K AI-2E family transporter
PKGKOOFP_01485 1.2e-60 EG EamA-like transporter family
PKGKOOFP_01486 7.4e-75 L haloacid dehalogenase-like hydrolase
PKGKOOFP_01487 1.7e-116 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PKGKOOFP_01488 1.7e-67 1.5.1.38 S NADPH-dependent FMN reductase
PKGKOOFP_01489 4.9e-164 C Luciferase-like monooxygenase
PKGKOOFP_01490 9.6e-42 K Transcriptional regulator, HxlR family
PKGKOOFP_01491 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PKGKOOFP_01492 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
PKGKOOFP_01493 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PKGKOOFP_01494 2.4e-82 pncA Q isochorismatase
PKGKOOFP_01495 9.3e-64 3.1.3.73 G phosphoglycerate mutase
PKGKOOFP_01496 2.8e-258 treB G phosphotransferase system
PKGKOOFP_01497 5.7e-84 treR K UTRA
PKGKOOFP_01498 8.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PKGKOOFP_01499 6.4e-168 mdtG EGP Major facilitator Superfamily
PKGKOOFP_01501 6.5e-157 XK27_08315 M Sulfatase
PKGKOOFP_01502 2.6e-35 XK27_08315 M Sulfatase
PKGKOOFP_01503 2.9e-55 S peptidoglycan catabolic process
PKGKOOFP_01504 6.7e-151 M BCCT, betaine/carnitine/choline family transporter
PKGKOOFP_01505 3.3e-84 M Nucleotidyl transferase
PKGKOOFP_01506 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
PKGKOOFP_01507 1.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PKGKOOFP_01508 2.6e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PKGKOOFP_01509 4.9e-126 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PKGKOOFP_01510 7e-177 thrC 4.2.3.1 E Threonine synthase
PKGKOOFP_01511 2.8e-160 XK27_08315 M Sulfatase
PKGKOOFP_01513 3.6e-14
PKGKOOFP_01514 1.2e-53 cps3I G Acyltransferase family
PKGKOOFP_01515 1.6e-145 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PKGKOOFP_01516 1.2e-39 2.7.7.65 T phosphorelay sensor kinase activity
PKGKOOFP_01517 7e-157 XK27_09615 S reductase
PKGKOOFP_01518 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
PKGKOOFP_01519 4.7e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PKGKOOFP_01520 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PKGKOOFP_01521 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PKGKOOFP_01523 5.3e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
PKGKOOFP_01524 1.5e-195 glf 5.4.99.9 M UDP-galactopyranose mutase
PKGKOOFP_01525 2.5e-109 S Psort location CytoplasmicMembrane, score
PKGKOOFP_01526 1.2e-62 M Glycosyltransferase like family 2
PKGKOOFP_01527 2.8e-74 M LicD family
PKGKOOFP_01528 6.9e-58 cps3F
PKGKOOFP_01529 5.2e-94 M transferase activity, transferring glycosyl groups
PKGKOOFP_01530 1.7e-76 waaB GT4 M Glycosyl transferases group 1
PKGKOOFP_01531 3.1e-92 M Core-2/I-Branching enzyme
PKGKOOFP_01532 2.8e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PKGKOOFP_01533 1e-64 rny D Peptidase family M23
PKGKOOFP_01535 3.1e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PKGKOOFP_01536 4.3e-165 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PKGKOOFP_01537 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PKGKOOFP_01538 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PKGKOOFP_01539 1e-90 rfbP M Bacterial sugar transferase
PKGKOOFP_01540 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PKGKOOFP_01541 1.2e-111 ywqE 3.1.3.48 GM PHP domain protein
PKGKOOFP_01542 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PKGKOOFP_01543 6e-74 epsB M biosynthesis protein
PKGKOOFP_01545 4.2e-115 cps2J S Polysaccharide biosynthesis protein
PKGKOOFP_01546 1.2e-67 S Polysaccharide pyruvyl transferase
PKGKOOFP_01548 4.5e-28 M family 8
PKGKOOFP_01549 8.7e-91
PKGKOOFP_01550 5.9e-37 M group 2 family protein
PKGKOOFP_01552 1.9e-43 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_01553 6.7e-114 L Transposase IS66 family
PKGKOOFP_01554 8.6e-33 M Glycosyl transferase family 8
PKGKOOFP_01555 8e-29 M Glycosyl transferase family 8
PKGKOOFP_01556 9.8e-80 L PFAM Integrase catalytic region
PKGKOOFP_01557 1e-29 L Helix-turn-helix domain
PKGKOOFP_01558 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PKGKOOFP_01559 1.3e-133 coaA 2.7.1.33 F Pantothenic acid kinase
PKGKOOFP_01560 1.7e-44 E GDSL-like Lipase/Acylhydrolase
PKGKOOFP_01561 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKGKOOFP_01562 1.3e-189 glnPH2 P ABC transporter permease
PKGKOOFP_01563 1.6e-213 yjeM E Amino Acid
PKGKOOFP_01564 3e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
PKGKOOFP_01565 4.3e-137 tetA EGP Major facilitator Superfamily
PKGKOOFP_01566 5e-62 S Glycosyltransferase like family 2
PKGKOOFP_01567 5.3e-118 cps1D M Domain of unknown function (DUF4422)
PKGKOOFP_01568 3e-39 S CAAX protease self-immunity
PKGKOOFP_01569 9.1e-89 yvyE 3.4.13.9 S YigZ family
PKGKOOFP_01570 2.9e-58 S Haloacid dehalogenase-like hydrolase
PKGKOOFP_01571 3.4e-154 EGP Major facilitator Superfamily
PKGKOOFP_01573 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PKGKOOFP_01574 1.2e-27 yraB K transcriptional regulator
PKGKOOFP_01575 2.2e-89 S NADPH-dependent FMN reductase
PKGKOOFP_01576 5.2e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PKGKOOFP_01577 1.5e-55 S ECF transporter, substrate-specific component
PKGKOOFP_01578 8.1e-95 znuB U ABC 3 transport family
PKGKOOFP_01579 2.9e-98 fhuC P ABC transporter
PKGKOOFP_01580 3e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
PKGKOOFP_01581 9.7e-41
PKGKOOFP_01582 6.5e-54 XK27_01040 S Protein of unknown function (DUF1129)
PKGKOOFP_01583 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PKGKOOFP_01584 9e-24 yyzM S Bacterial protein of unknown function (DUF951)
PKGKOOFP_01585 1.8e-108 spo0J K Belongs to the ParB family
PKGKOOFP_01586 6.5e-118 soj D Sporulation initiation inhibitor
PKGKOOFP_01587 8.3e-82 noc K Belongs to the ParB family
PKGKOOFP_01588 8.1e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PKGKOOFP_01589 4.5e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PKGKOOFP_01590 2.4e-106 3.1.4.46 C phosphodiesterase
PKGKOOFP_01591 0.0 pacL 3.6.3.8 P P-type ATPase
PKGKOOFP_01592 6.7e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
PKGKOOFP_01593 3.1e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PKGKOOFP_01595 6.2e-64 srtA 3.4.22.70 M sortase family
PKGKOOFP_01596 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PKGKOOFP_01597 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PKGKOOFP_01598 3.7e-34
PKGKOOFP_01599 1.4e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PKGKOOFP_01600 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PKGKOOFP_01601 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PKGKOOFP_01602 1.1e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
PKGKOOFP_01603 1.1e-39 ybjQ S Belongs to the UPF0145 family
PKGKOOFP_01604 3.3e-08
PKGKOOFP_01605 1.4e-95 V ABC transporter, ATP-binding protein
PKGKOOFP_01606 3.1e-41 gntR1 K Transcriptional regulator, GntR family
PKGKOOFP_01607 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PKGKOOFP_01608 8.2e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKGKOOFP_01609 1.6e-260 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
PKGKOOFP_01610 1.7e-107 terC P Integral membrane protein TerC family
PKGKOOFP_01611 1.6e-38 K Transcriptional regulator
PKGKOOFP_01612 2.2e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PKGKOOFP_01613 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PKGKOOFP_01614 4.5e-102 tcyB E ABC transporter
PKGKOOFP_01616 3.2e-29 ponA V the current gene model (or a revised gene model) may contain a frame shift
PKGKOOFP_01617 4.7e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PKGKOOFP_01618 1.7e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PKGKOOFP_01619 6.8e-210 mtlR K Mga helix-turn-helix domain
PKGKOOFP_01620 9.8e-177 yjcE P Sodium proton antiporter
PKGKOOFP_01621 1.1e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PKGKOOFP_01622 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
PKGKOOFP_01623 1.6e-68 dhaL 2.7.1.121 S Dak2
PKGKOOFP_01624 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PKGKOOFP_01625 2.4e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PKGKOOFP_01626 1.7e-61 K Bacterial regulatory proteins, tetR family
PKGKOOFP_01627 3.8e-209 brnQ U Component of the transport system for branched-chain amino acids
PKGKOOFP_01629 2.9e-111 endA F DNA RNA non-specific endonuclease
PKGKOOFP_01630 4.1e-75 XK27_02070 S Nitroreductase family
PKGKOOFP_01631 5.9e-192 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PKGKOOFP_01632 2.9e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
PKGKOOFP_01633 1.8e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
PKGKOOFP_01634 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PKGKOOFP_01635 9.3e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PKGKOOFP_01636 1.5e-76 azlC E branched-chain amino acid
PKGKOOFP_01637 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
PKGKOOFP_01638 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
PKGKOOFP_01639 1.6e-55 jag S R3H domain protein
PKGKOOFP_01640 2.7e-120 sip L Belongs to the 'phage' integrase family
PKGKOOFP_01641 2e-09 E IrrE N-terminal-like domain
PKGKOOFP_01642 1.8e-31 K Helix-turn-helix XRE-family like proteins
PKGKOOFP_01643 2e-07 K Helix-turn-helix XRE-family like proteins
PKGKOOFP_01644 6.1e-20 K Transcriptional regulator
PKGKOOFP_01651 8.7e-46 L Bifunctional DNA primase/polymerase, N-terminal
PKGKOOFP_01652 2.5e-132 S D5 N terminal like
PKGKOOFP_01654 1.4e-16
PKGKOOFP_01656 9.1e-54 K Transcriptional regulator C-terminal region
PKGKOOFP_01657 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
PKGKOOFP_01658 7.6e-285 pepO 3.4.24.71 O Peptidase family M13
PKGKOOFP_01659 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
PKGKOOFP_01660 1.2e-07 yvaZ S SdpI/YhfL protein family
PKGKOOFP_01661 1e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PKGKOOFP_01662 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
PKGKOOFP_01663 1.3e-40 wecD K Acetyltransferase GNAT Family
PKGKOOFP_01665 1.3e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
PKGKOOFP_01666 9.8e-251 XK27_06780 V ABC transporter permease
PKGKOOFP_01667 2.9e-40 XK27_06785 V ABC transporter, ATP-binding protein
PKGKOOFP_01668 4.5e-46 XK27_06785 V ABC transporter, ATP-binding protein
PKGKOOFP_01669 5.7e-15 tetR K transcriptional regulator
PKGKOOFP_01670 1e-08 tetR K transcriptional regulator
PKGKOOFP_01671 2.1e-19
PKGKOOFP_01673 4.9e-71 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PKGKOOFP_01674 3.1e-121 ytbE S reductase
PKGKOOFP_01675 4.2e-43 ytcD K HxlR-like helix-turn-helix
PKGKOOFP_01676 1.2e-100 ybbM S Uncharacterised protein family (UPF0014)
PKGKOOFP_01677 3.4e-67 ybbL S ABC transporter
PKGKOOFP_01678 1.8e-162 oxlT P Major Facilitator Superfamily
PKGKOOFP_01679 4.7e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PKGKOOFP_01680 1.6e-46 S Short repeat of unknown function (DUF308)
PKGKOOFP_01681 1.8e-30 tetR K Transcriptional regulator C-terminal region
PKGKOOFP_01682 1.2e-150 yfeX P Peroxidase
PKGKOOFP_01683 2.5e-16 S Protein of unknown function (DUF3021)
PKGKOOFP_01684 4.5e-39 K LytTr DNA-binding domain
PKGKOOFP_01685 1.8e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PKGKOOFP_01686 1.3e-209 mmuP E amino acid
PKGKOOFP_01687 9.2e-16 psiE S Phosphate-starvation-inducible E
PKGKOOFP_01688 2.2e-155 oppF P Belongs to the ABC transporter superfamily
PKGKOOFP_01689 8.1e-180 oppD P Belongs to the ABC transporter superfamily
PKGKOOFP_01690 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PKGKOOFP_01691 4.6e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PKGKOOFP_01692 6.2e-203 oppA E ABC transporter, substratebinding protein
PKGKOOFP_01693 1.7e-217 yifK E Amino acid permease
PKGKOOFP_01694 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PKGKOOFP_01695 5.7e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PKGKOOFP_01696 8.4e-66 pgm3 G phosphoglycerate mutase family
PKGKOOFP_01697 1e-249 ctpA 3.6.3.54 P P-type ATPase
PKGKOOFP_01698 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PKGKOOFP_01699 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PKGKOOFP_01700 4.8e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PKGKOOFP_01701 1.2e-21 K transcriptional regulator
PKGKOOFP_01702 3.8e-77 hchA S intracellular protease amidase
PKGKOOFP_01703 4.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PKGKOOFP_01704 1.8e-112 lacI3 K helix_turn _helix lactose operon repressor
PKGKOOFP_01705 2.7e-230 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
PKGKOOFP_01706 7.5e-39 2.7.1.191 G PTS system fructose IIA component
PKGKOOFP_01707 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
PKGKOOFP_01708 4.4e-101 G PTS system sorbose-specific iic component
PKGKOOFP_01709 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
PKGKOOFP_01710 4.3e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PKGKOOFP_01711 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PKGKOOFP_01712 6.4e-200 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
PKGKOOFP_01713 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
PKGKOOFP_01714 6.4e-196 1.3.5.4 C FMN_bind
PKGKOOFP_01715 2.2e-56 3.1.3.48 K Transcriptional regulator
PKGKOOFP_01716 1.2e-159 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PKGKOOFP_01717 7e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PKGKOOFP_01718 4.4e-75 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PKGKOOFP_01719 9.5e-26 yxjG 2.1.1.14 E Methionine synthase
PKGKOOFP_01720 4.5e-66 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
PKGKOOFP_01721 2e-94 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PKGKOOFP_01722 4.3e-82 S Belongs to the UPF0246 family
PKGKOOFP_01723 5.6e-10 S CAAX protease self-immunity
PKGKOOFP_01724 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
PKGKOOFP_01725 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PKGKOOFP_01727 7.4e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PKGKOOFP_01728 5.3e-64 C FMN binding
PKGKOOFP_01729 2.6e-205 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PKGKOOFP_01730 1.7e-54 rplI J Binds to the 23S rRNA
PKGKOOFP_01731 1.8e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PKGKOOFP_01732 7.9e-07
PKGKOOFP_01738 5.1e-08
PKGKOOFP_01747 9e-30 yqkB S Belongs to the HesB IscA family
PKGKOOFP_01748 4.6e-66 yxkH G Polysaccharide deacetylase
PKGKOOFP_01749 2.8e-08
PKGKOOFP_01750 2.9e-53 K LysR substrate binding domain
PKGKOOFP_01751 9.9e-122 MA20_14895 S Conserved hypothetical protein 698
PKGKOOFP_01752 1.1e-199 nupG F Nucleoside
PKGKOOFP_01753 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PKGKOOFP_01754 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PKGKOOFP_01755 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PKGKOOFP_01756 4.3e-26 K Cro/C1-type HTH DNA-binding domain
PKGKOOFP_01757 2.4e-15 S Putative inner membrane protein (DUF1819)
PKGKOOFP_01758 8.7e-19 S Putative inner membrane protein (DUF1819)
PKGKOOFP_01759 4.6e-21 S Putative inner membrane protein (DUF1819)
PKGKOOFP_01760 2.6e-68 S Domain of unknown function (DUF1788)
PKGKOOFP_01761 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
PKGKOOFP_01762 0.0 V restriction
PKGKOOFP_01763 2.8e-306 S TIGR02687 family
PKGKOOFP_01764 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
PKGKOOFP_01765 8.4e-50
PKGKOOFP_01766 7.7e-35
PKGKOOFP_01767 1.5e-08
PKGKOOFP_01768 3.5e-16
PKGKOOFP_01769 5.7e-24
PKGKOOFP_01772 3.5e-156 potE2 E amino acid
PKGKOOFP_01773 2.1e-146 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PKGKOOFP_01774 4e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PKGKOOFP_01775 2.8e-56 racA K Domain of unknown function (DUF1836)
PKGKOOFP_01776 3.8e-79 yitS S EDD domain protein, DegV family
PKGKOOFP_01777 8.1e-88 L PFAM Integrase catalytic region
PKGKOOFP_01778 2.6e-30 L Helix-turn-helix domain
PKGKOOFP_01780 1.2e-15 yjaB_1 K Acetyltransferase (GNAT) domain
PKGKOOFP_01781 2.8e-08 yjaB_1 K PFAM Acetyltransferase (GNAT) family
PKGKOOFP_01782 3.1e-08
PKGKOOFP_01783 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PKGKOOFP_01784 0.0 O Belongs to the peptidase S8 family
PKGKOOFP_01785 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
PKGKOOFP_01786 2.5e-58 tlpA2 L Transposase IS200 like
PKGKOOFP_01787 1.1e-157 L transposase, IS605 OrfB family
PKGKOOFP_01788 4.6e-84 dps P Ferritin-like domain
PKGKOOFP_01789 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PKGKOOFP_01790 1.6e-43 L hmm pf00665
PKGKOOFP_01791 1.7e-18 tnp
PKGKOOFP_01792 8.7e-31 tnp L Transposase IS66 family
PKGKOOFP_01793 1.7e-32 P Heavy-metal-associated domain
PKGKOOFP_01794 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
PKGKOOFP_01795 1.8e-20 L PFAM transposase IS3 IS911 family protein
PKGKOOFP_01796 1.4e-41 L Integrase core domain
PKGKOOFP_01797 1.8e-35 L Integrase core domain
PKGKOOFP_01798 5.8e-129 EGP Major Facilitator Superfamily
PKGKOOFP_01799 1.8e-98 EGP Major Facilitator Superfamily
PKGKOOFP_01800 7.5e-73 K Transcriptional regulator, LysR family
PKGKOOFP_01801 4.7e-138 G Xylose isomerase-like TIM barrel
PKGKOOFP_01802 1.9e-115 IQ Enoyl-(Acyl carrier protein) reductase
PKGKOOFP_01803 4.7e-217 1.3.5.4 C FAD binding domain
PKGKOOFP_01804 1.9e-137 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PKGKOOFP_01805 2e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PKGKOOFP_01806 1.1e-142 xerS L Phage integrase family
PKGKOOFP_01809 1.6e-42 S YjcQ protein
PKGKOOFP_01812 5.6e-106 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PKGKOOFP_01813 3.6e-36 ptp3 3.1.3.48 T Tyrosine phosphatase family
PKGKOOFP_01814 4e-23 ptp3 3.1.3.48 T Tyrosine phosphatase family
PKGKOOFP_01815 1.8e-75 desR K helix_turn_helix, Lux Regulon
PKGKOOFP_01816 1.9e-57 salK 2.7.13.3 T Histidine kinase
PKGKOOFP_01817 1.4e-53 yvfS V ABC-2 type transporter
PKGKOOFP_01818 1.5e-78 yvfR V ABC transporter
PKGKOOFP_01820 3.4e-10 S Protein of unknown function (DUF805)
PKGKOOFP_01821 1.8e-08 K transcriptional
PKGKOOFP_01822 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PKGKOOFP_01823 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PKGKOOFP_01824 1.5e-29
PKGKOOFP_01825 8.2e-16
PKGKOOFP_01826 2.1e-112 rssA S Phospholipase, patatin family
PKGKOOFP_01827 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PKGKOOFP_01828 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PKGKOOFP_01829 3.3e-45 S VIT family
PKGKOOFP_01830 9.4e-240 sufB O assembly protein SufB
PKGKOOFP_01831 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
PKGKOOFP_01832 3.3e-148 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PKGKOOFP_01833 5.6e-143 sufD O FeS assembly protein SufD
PKGKOOFP_01834 1.4e-115 sufC O FeS assembly ATPase SufC
PKGKOOFP_01835 1.1e-223 E ABC transporter, substratebinding protein
PKGKOOFP_01837 1e-19 S protein encoded in hypervariable junctions of pilus gene clusters
PKGKOOFP_01838 2.5e-27 K Helix-turn-helix XRE-family like proteins
PKGKOOFP_01839 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PKGKOOFP_01840 1.2e-51 3.1.21.3 V type I restriction modification DNA specificity domain
PKGKOOFP_01841 5.7e-127 xerC L Belongs to the 'phage' integrase family
PKGKOOFP_01842 4.2e-57 3.1.21.3 V type I restriction modification DNA specificity domain
PKGKOOFP_01843 2.5e-31 3.1.21.3 L Type I restriction modification DNA specificity domain
PKGKOOFP_01844 4.9e-250 2.1.1.72 V type I restriction-modification system
PKGKOOFP_01845 4.8e-58 hsdM 2.1.1.72 V HsdM N-terminal domain
PKGKOOFP_01846 2.2e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
PKGKOOFP_01847 9.5e-136 pfoS S Phosphotransferase system, EIIC
PKGKOOFP_01848 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PKGKOOFP_01849 2e-65 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
PKGKOOFP_01850 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PKGKOOFP_01851 1.1e-94 L Transposase, IS605 OrfB family
PKGKOOFP_01852 2e-55 tlpA2 L Transposase IS200 like
PKGKOOFP_01853 4.7e-163 ytbD EGP Major facilitator Superfamily
PKGKOOFP_01854 5.7e-97 fabK 1.3.1.9 S Nitronate monooxygenase
PKGKOOFP_01855 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PKGKOOFP_01856 9.2e-185 tonB M YSIRK type signal peptide
PKGKOOFP_01857 2.8e-266 fbp 3.1.3.11 G phosphatase activity
PKGKOOFP_01858 2.9e-71 xerD L Phage integrase, N-terminal SAM-like domain
PKGKOOFP_01861 1e-87 S Haloacid dehalogenase-like hydrolase
PKGKOOFP_01862 2.7e-15
PKGKOOFP_01864 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
PKGKOOFP_01865 2.2e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PKGKOOFP_01866 3.4e-67 S Protein of unknown function (DUF1440)
PKGKOOFP_01867 7.7e-41 S Iron-sulfur cluster assembly protein
PKGKOOFP_01868 5.5e-113 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PKGKOOFP_01869 2.1e-72 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PKGKOOFP_01870 2.3e-73 L PFAM transposase IS200-family protein
PKGKOOFP_01871 8.6e-207 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PKGKOOFP_01872 6.6e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PKGKOOFP_01873 1.4e-64 G Xylose isomerase domain protein TIM barrel
PKGKOOFP_01874 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
PKGKOOFP_01875 2.9e-90 nanK GK ROK family
PKGKOOFP_01876 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PKGKOOFP_01877 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PKGKOOFP_01878 1.9e-75 K Helix-turn-helix domain, rpiR family
PKGKOOFP_01879 5.3e-62 yphA GM NAD dependent epimerase/dehydratase family
PKGKOOFP_01880 2e-216 yjeM E Amino Acid
PKGKOOFP_01882 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PKGKOOFP_01883 8.8e-231 tetP J elongation factor G
PKGKOOFP_01885 1.6e-10 tcdC
PKGKOOFP_01887 2.1e-107 L PLD-like domain
PKGKOOFP_01888 1.7e-29 L Helix-turn-helix domain
PKGKOOFP_01889 2.6e-74 L HTH-like domain
PKGKOOFP_01890 3.5e-23 L PLD-like domain
PKGKOOFP_01891 6.5e-12 L PLD-like domain
PKGKOOFP_01893 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
PKGKOOFP_01894 9.4e-109 L Initiator Replication protein
PKGKOOFP_01895 1.9e-37 S Replication initiator protein A (RepA) N-terminus
PKGKOOFP_01896 1.7e-144 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PKGKOOFP_01897 1.6e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PKGKOOFP_01898 1.4e-12 bglG K antiterminator
PKGKOOFP_01899 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
PKGKOOFP_01901 1.8e-31
PKGKOOFP_01902 6.7e-114 L Transposase IS66 family
PKGKOOFP_01903 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
PKGKOOFP_01905 0.0 pepN 3.4.11.2 E aminopeptidase
PKGKOOFP_01906 3e-43 blpH 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PKGKOOFP_01907 1.6e-22 agrA KT Response regulator of the LytR AlgR family
PKGKOOFP_01909 1.4e-19 M domain protein
PKGKOOFP_01914 3.6e-125 yvgN C Aldo keto reductase
PKGKOOFP_01915 1.7e-122 yvgN C Aldo keto reductase
PKGKOOFP_01916 8.8e-10 K DeoR C terminal sensor domain
PKGKOOFP_01917 1.1e-51 K DeoR C terminal sensor domain
PKGKOOFP_01918 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PKGKOOFP_01919 6.9e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PKGKOOFP_01920 1.2e-216 pts36C G PTS system sugar-specific permease component
PKGKOOFP_01922 2.3e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
PKGKOOFP_01924 6.2e-29 S COG NOG19168 non supervised orthologous group
PKGKOOFP_01925 6.4e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
PKGKOOFP_01926 2.7e-14 L Plasmid pRiA4b ORF-3-like protein
PKGKOOFP_01927 2e-105 L Belongs to the 'phage' integrase family
PKGKOOFP_01928 8.6e-19 3.1.21.3 V Type I restriction modification DNA specificity domain
PKGKOOFP_01929 8.6e-60 hsdM 2.1.1.72 V HsdM N-terminal domain
PKGKOOFP_01931 7.1e-55 repA S Replication initiator protein A (RepA) N-terminus
PKGKOOFP_01932 1.5e-16 S Fic/DOC family
PKGKOOFP_01933 7.4e-08 S Fic/DOC family
PKGKOOFP_01934 1.6e-85 S Fic/DOC family
PKGKOOFP_01935 9.9e-40 relB L Addiction module antitoxin, RelB DinJ family
PKGKOOFP_01936 1.1e-45 S protein conserved in bacteria
PKGKOOFP_01937 5.6e-24
PKGKOOFP_01938 3.1e-44 L MobA MobL family protein
PKGKOOFP_01939 5.2e-299 L MobA MobL family protein
PKGKOOFP_01940 1.5e-42 hxlR K Transcriptional regulator, HxlR family
PKGKOOFP_01941 1.1e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PKGKOOFP_01942 3.8e-93
PKGKOOFP_01943 4.2e-48 L Transposase
PKGKOOFP_01944 1.8e-76 cylA V abc transporter atp-binding protein
PKGKOOFP_01945 4.1e-60 cylB V ABC-2 type transporter
PKGKOOFP_01946 7e-27 K LytTr DNA-binding domain
PKGKOOFP_01947 3.7e-11 S Protein of unknown function (DUF3021)
PKGKOOFP_01948 2.1e-157 L Transposase
PKGKOOFP_01949 7.5e-49 L Transposase
PKGKOOFP_01950 1.3e-12
PKGKOOFP_01951 4.6e-79
PKGKOOFP_01952 8.7e-51 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PKGKOOFP_01953 4e-256 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PKGKOOFP_01954 0.0 M Cna protein B-type domain
PKGKOOFP_01955 8.5e-89 2.7.7.65 T phosphorelay sensor kinase activity
PKGKOOFP_01956 1.3e-132 cbiQ P Cobalt transport protein
PKGKOOFP_01957 1.3e-156 P ABC transporter
PKGKOOFP_01958 1.2e-149 cbiO2 P ABC transporter
PKGKOOFP_01959 3.3e-265 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PKGKOOFP_01960 9.3e-178 proV E ABC transporter, ATP-binding protein
PKGKOOFP_01961 8.9e-248 gshR 1.8.1.7 C Glutathione reductase
PKGKOOFP_01962 2.5e-101 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PKGKOOFP_01963 4.3e-107
PKGKOOFP_01964 3.5e-40 S RelB antitoxin
PKGKOOFP_01965 1.2e-43
PKGKOOFP_01966 3.6e-32 L Transposase
PKGKOOFP_01967 2.7e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PKGKOOFP_01968 2.6e-99 S Signal peptide protein, YSIRK family
PKGKOOFP_01969 5.1e-77 K response regulator
PKGKOOFP_01970 1.3e-89 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PKGKOOFP_01971 2e-23 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PKGKOOFP_01972 1.8e-110 L hmm pf00665
PKGKOOFP_01973 2.5e-104 L Helix-turn-helix domain
PKGKOOFP_01974 3.6e-57 pncA Q Isochorismatase family
PKGKOOFP_01975 8.1e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PKGKOOFP_01976 1.4e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
PKGKOOFP_01977 7.7e-18 tnp L MULE transposase domain
PKGKOOFP_01978 1.9e-63 V HNH endonuclease
PKGKOOFP_01980 1.4e-102 tnp L MULE transposase domain
PKGKOOFP_01981 8.9e-23 tnp L MULE transposase domain
PKGKOOFP_01982 4.7e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PKGKOOFP_01983 1.9e-53 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
PKGKOOFP_01984 4.9e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
PKGKOOFP_01985 8.5e-35

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)