ORF_ID e_value Gene_name EC_number CAZy COGs Description
NECFGCCN_00001 2.7e-105 pat 2.3.1.183 M N-acetyltransferase
NECFGCCN_00002 0.0 dld 1.1.5.12 C Catalyzes the oxidation of D-lactate to pyruvate
NECFGCCN_00003 0.0 bglX 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
NECFGCCN_00004 1.9e-164 yehZ M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NECFGCCN_00005 5.4e-201 yehY P permease
NECFGCCN_00006 1.5e-172 yehX E abc transporter atp-binding protein
NECFGCCN_00007 7.6e-124 yehW P permease
NECFGCCN_00008 5.7e-10 yohO S UPF0387 membrane protein YohO
NECFGCCN_00009 2.1e-305 yehU 2.7.13.3 T Histidine kinase
NECFGCCN_00010 2.2e-128 yehT KT Response regulator of the LytR AlgR family
NECFGCCN_00011 1.8e-78 yehS S protein conserved in bacteria
NECFGCCN_00012 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NECFGCCN_00013 5.2e-209 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NECFGCCN_00014 8.9e-51 yjaB_1 2.3.1.210 K N-acetyltransferase
NECFGCCN_00015 8.5e-56 yohN S Nickel cobalt homeostasis protein RcnB
NECFGCCN_00016 2.4e-164 K Transcriptional regulator
NECFGCCN_00017 2.9e-238 yicO S permease
NECFGCCN_00018 0.0 ade 3.5.4.2 F adenine deaminase
NECFGCCN_00019 2.2e-149 K Transcriptional regulator
NECFGCCN_00020 1.3e-67 uspA2 T Universal stress protein
NECFGCCN_00021 1.2e-132 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NECFGCCN_00022 1e-142 thiD 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NECFGCCN_00023 5.1e-198 fbaB 4.1.2.13 G Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate
NECFGCCN_00024 1.4e-120 P Major facilitator superfamily
NECFGCCN_00025 4.9e-126 2.7.1.176 O Zeta toxin
NECFGCCN_00026 9.7e-80 nprA K Cro/C1-type HTH DNA-binding domain
NECFGCCN_00027 1.2e-34
NECFGCCN_00028 2.9e-48 XK27_00545 U This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NECFGCCN_00029 5.1e-63 P arsenate reductase (glutaredoxin) activity
NECFGCCN_00030 1.4e-62 XK27_00590
NECFGCCN_00031 8.8e-107 S type VI secretion protein
NECFGCCN_00032 4.2e-253 S type VI secretion protein
NECFGCCN_00033 1.3e-96 S Type IV VI secretion system
NECFGCCN_00034 3.4e-106 abiGI K Transcriptional regulator, AbiEi antitoxin
NECFGCCN_00035 0.0 mhpA 1.14.13.127 CH Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI)
NECFGCCN_00036 3.5e-166 mhpB 1.13.11.16 S Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively
NECFGCCN_00037 2.7e-168 mhpC 3.7.1.14, 3.7.1.17 I Alpha/beta hydrolase family
NECFGCCN_00038 4.4e-149 mhpD 4.2.1.80 Q hydratase
NECFGCCN_00039 2e-169 mhpF 1.2.1.10 Q Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds
NECFGCCN_00040 3.4e-183 mhpE 4.1.3.39 E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds
NECFGCCN_00041 8.5e-141 mhpT EGP Major facilitator Superfamily
NECFGCCN_00042 1.2e-137 yfiH S Multi-copper polyphenol oxidoreductase laccase
NECFGCCN_00043 1.4e-292 MA20_21580 2.8.1.11 P sulfurtransferase
NECFGCCN_00044 1.1e-112 S Cysteine dioxygenase type I
NECFGCCN_00045 3.7e-149 K Transcriptional regulator
NECFGCCN_00046 3.4e-205 ssuD_2 1.14.14.5 C Alkanesulfonate monooxygenase
NECFGCCN_00047 5.2e-53 ydbM I acyl-CoA dehydrogenase
NECFGCCN_00048 4.1e-44 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NECFGCCN_00049 7.9e-185
NECFGCCN_00050 1.9e-81 FNV0100 F Belongs to the Nudix hydrolase family
NECFGCCN_00051 8.2e-73 XK27_01300 P Protein conserved in bacteria
NECFGCCN_00052 9.4e-107 ynjF 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NECFGCCN_00053 5.1e-69 nudG 3.6.1.55, 3.6.1.65 L belongs to the nudix hydrolase family
NECFGCCN_00054 3.3e-258 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NECFGCCN_00055 1.3e-179 qor 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NECFGCCN_00056 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NECFGCCN_00057 2.4e-195 selD 2.7.9.3 F Synthesizes selenophosphate from selenide and ATP
NECFGCCN_00058 1.8e-136 pho 3.1.3.2 I Acid phosphatase
NECFGCCN_00059 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NECFGCCN_00060 2.8e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NECFGCCN_00061 1e-34
NECFGCCN_00062 1.3e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NECFGCCN_00063 1.4e-162 yxeN P ABC transporter (Permease
NECFGCCN_00064 6.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_00065 1.2e-76 S dextransucrase activity
NECFGCCN_00066 1.8e-240 norM V Multidrug efflux pump
NECFGCCN_00068 8.8e-181 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NECFGCCN_00069 1.1e-229 brnQ E Component of the transport system for branched-chain amino acids
NECFGCCN_00070 1.7e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
NECFGCCN_00071 4e-59 S Protein of unknown function (DUF3290)
NECFGCCN_00072 2.8e-106 S Protein of unknown function (DUF421)
NECFGCCN_00073 1.1e-16 csbD S CsbD-like
NECFGCCN_00074 2.2e-109 S Carbohydrate-binding domain-containing protein Cthe_2159
NECFGCCN_00075 1.6e-67 prkC 2.7.11.1 KLT serine threonine protein kinase
NECFGCCN_00076 2.6e-135 stp 3.1.3.16 T phosphatase
NECFGCCN_00077 5e-93 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NECFGCCN_00078 6.5e-146 nasE P ABC-type nitrate sulfonate bicarbonate transport system permease component
NECFGCCN_00079 4e-242 nasF P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NECFGCCN_00080 7.5e-190 nasR K Nitrate and nitrite sensing domain protein
NECFGCCN_00081 6.6e-57 ychN P conserved protein involved in intracellular sulfur reduction
NECFGCCN_00082 3.3e-39 S Protein involved in biological_process
NECFGCCN_00083 3.6e-128 chaC P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NECFGCCN_00084 1.9e-36 chaB S Cation transport regulator
NECFGCCN_00085 4e-185 chaA P Calcium Proton
NECFGCCN_00086 2.2e-159 kdsA 2.5.1.55 M Belongs to the KdsA family
NECFGCCN_00087 1.2e-149 ychA S Transglutaminase-like superfamily
NECFGCCN_00088 7.3e-65 sirB2 S Invasion gene expression up-regulator SirB
NECFGCCN_00089 4.8e-146 prmC 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NECFGCCN_00090 8.4e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NECFGCCN_00091 9.4e-223 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NECFGCCN_00092 4.5e-114 lolB M Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NECFGCCN_00093 8.6e-69 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NECFGCCN_00094 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NECFGCCN_00095 1.1e-231 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NECFGCCN_00096 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NECFGCCN_00097 4.8e-182 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NECFGCCN_00098 1.1e-189 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NECFGCCN_00099 1.8e-53 nasD 3.6.3.36 P (ABC) transporter
NECFGCCN_00100 3.6e-186 desK 2.7.13.3 T Histidine kinase
NECFGCCN_00101 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECFGCCN_00102 5.8e-55 S TM2 domain
NECFGCCN_00103 3.7e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NECFGCCN_00104 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NECFGCCN_00105 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
NECFGCCN_00106 3.5e-82 ywbD 2.1.1.191 J Methyltransferase
NECFGCCN_00107 1.1e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NECFGCCN_00108 6.3e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NECFGCCN_00109 1.7e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NECFGCCN_00110 1.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NECFGCCN_00111 2e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NECFGCCN_00112 1.2e-52 yheA S Belongs to the UPF0342 family
NECFGCCN_00113 7e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NECFGCCN_00114 1.3e-232 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NECFGCCN_00115 2.7e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NECFGCCN_00116 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
NECFGCCN_00118 1.3e-130 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NECFGCCN_00119 2.9e-15 dnaX 2.4.99.16, 2.7.7.7 GH13 D cell septum assembly
NECFGCCN_00124 1.4e-37 yclQ P ABC-type enterochelin transport system, periplasmic component
NECFGCCN_00125 2.4e-40 pspC KT PspC domain
NECFGCCN_00126 5.5e-59 livG E Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids
NECFGCCN_00127 2.3e-22 niaR S small molecule binding protein (contains 3H domain)
NECFGCCN_00128 4.5e-86
NECFGCCN_00129 7.1e-201 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NECFGCCN_00130 1.5e-166 sufD O FeS assembly protein SufD
NECFGCCN_00131 2.2e-131 sufC O FeS assembly ATPase SufC
NECFGCCN_00132 2e-293 sufB O FeS assembly protein SufB
NECFGCCN_00133 9.8e-67 sufA S Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system
NECFGCCN_00134 2.6e-18
NECFGCCN_00135 3e-34 S DoxX
NECFGCCN_00136 8.7e-52 K transcriptional regulator
NECFGCCN_00137 5.7e-222 lldD 1.1.2.3 C Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain
NECFGCCN_00138 0.0 czcA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_00139 9.1e-90 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_00140 0.0 salB V Lanthionine synthetase C-like protein
NECFGCCN_00141 0.0 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NECFGCCN_00142 4.2e-122 V ABC transporter
NECFGCCN_00143 0.0 yfeA T MASE1
NECFGCCN_00144 1.1e-204 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NECFGCCN_00145 1.1e-210 mntH P H( )-stimulated, divalent metal cation uptake system
NECFGCCN_00146 5.5e-27 ypeC S Protein of unknown function (DUF2502)
NECFGCCN_00147 1.1e-181 yghZ C reductase
NECFGCCN_00148 1.6e-307 ipdC 4.1.1.74 GH Belongs to the TPP enzyme family
NECFGCCN_00149 8.9e-210 yfeO P ion-transport protein
NECFGCCN_00150 5.6e-183 glk 2.7.1.2 F Belongs to the bacterial glucokinase family
NECFGCCN_00151 6.9e-133 ypdB K response regulator
NECFGCCN_00152 4.7e-311 ypdA 2.7.13.3 T Histidine kinase
NECFGCCN_00153 3.2e-236 yfdZ 2.6.1.83 E aminotransferase
NECFGCCN_00154 2.7e-203 cynX P transporter
NECFGCCN_00155 3.2e-72 guaD 3.5.4.33 FJ deaminase
NECFGCCN_00156 1.1e-140 cynR K transcriptional regulator
NECFGCCN_00157 2.6e-142
NECFGCCN_00158 6e-85 5.3.1.9 G Cupin 2, conserved barrel domain protein
NECFGCCN_00160 3.3e-156 yfdC P Formate nitrite
NECFGCCN_00161 1.1e-146 vacJ M Lipoprotein
NECFGCCN_00162 4e-256 fadL I long-chain fatty acid transport protein
NECFGCCN_00163 9.4e-46 yfcZ S protein conserved in bacteria
NECFGCCN_00164 9.1e-237 fadI 2.3.1.16 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
NECFGCCN_00165 0.0 fadJ 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate
NECFGCCN_00166 5.8e-88 sixA T phosphohistidine phosphatase
NECFGCCN_00167 2.2e-99 yfcN S Belongs to the UPF0115 family
NECFGCCN_00168 3.1e-184 prmB 2.1.1.297, 2.1.1.298 J Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue
NECFGCCN_00169 1.5e-205 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NECFGCCN_00170 3.8e-156 mepA M Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
NECFGCCN_00171 9.2e-139 yfcA S membrane transporter protein
NECFGCCN_00172 1.6e-105 yfcM S protein conserved in bacteria
NECFGCCN_00173 3.3e-43 yfcL S YfcL protein
NECFGCCN_00174 0.0 mnmC 2.1.1.61, 2.1.1.72, 2.4.2.29, 4.2.1.151 J Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NECFGCCN_00175 1.2e-227 fabB 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NECFGCCN_00176 8.1e-257 pgi 5.3.1.9 G Belongs to the GPI family
NECFGCCN_00177 2.6e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
NECFGCCN_00178 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NECFGCCN_00179 1e-26 ptsG 2.7.1.199, 2.7.1.208 G pts system
NECFGCCN_00180 6.4e-160 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NECFGCCN_00181 1.7e-45 S membrane
NECFGCCN_00182 0.0 rafA 3.2.1.22 G alpha-galactosidase
NECFGCCN_00183 1.5e-231 lacY G Major facilitator superfamily
NECFGCCN_00184 5e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NECFGCCN_00185 8.3e-210 fucO 1.1.1.1 C alcohol dehydrogenase
NECFGCCN_00186 1.1e-173 rhaQ U Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_00187 1.5e-175 rhaP U Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_00188 8.5e-279 rbsA 3.6.3.17 P import. Responsible for energy coupling to the transport system
NECFGCCN_00189 1.2e-172 rhaS G (ABC) transporter
NECFGCCN_00190 8.8e-161 rhaD 4.1.1.104, 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NECFGCCN_00191 1e-248 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase
NECFGCCN_00192 1.5e-280 rhaB 2.7.1.17, 2.7.1.189, 2.7.1.5, 2.7.1.51, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NECFGCCN_00193 1.8e-158 rhaS K Activates expression of the rhaBAD and rhaT operons
NECFGCCN_00194 2e-160 rhaR K Activates expression of the rhaSR operon in response to L-rhamnose
NECFGCCN_00195 4e-187 rhaT U Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system)
NECFGCCN_00196 2.2e-116 sodA 1.15.1.1 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NECFGCCN_00197 4e-127 yiiM C protein conserved in bacteria
NECFGCCN_00198 5.4e-240 T PhoQ Sensor
NECFGCCN_00199 3.1e-127 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_00200 9.3e-81 cpxP NPTU Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA
NECFGCCN_00201 8.1e-160 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NECFGCCN_00202 1.1e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
NECFGCCN_00203 2.9e-87 rraA H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NECFGCCN_00204 1.1e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NECFGCCN_00205 1.1e-242 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NECFGCCN_00206 4.2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NECFGCCN_00207 1.1e-110 ftsN D Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases
NECFGCCN_00208 5.4e-192 cytR K transcriptional
NECFGCCN_00209 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NECFGCCN_00210 3e-36 rpmE J Binds the 23S rRNA
NECFGCCN_00211 1.8e-53 metJ K This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
NECFGCCN_00212 1.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide
NECFGCCN_00213 0.0 metL 1.1.1.3, 2.7.2.4 E belongs to the aspartokinase family
NECFGCCN_00214 2e-73 tnp3503b 2.7.7.7 L Transposase
NECFGCCN_00215 2.2e-277 soxB 3.1.3.5, 3.6.1.45 F 5'-nucleotidase, C-terminal domain
NECFGCCN_00216 5.3e-57 MA20_13090 4.1.1.44 S decarboxylase
NECFGCCN_00217 1.3e-152 K transcriptional regulator
NECFGCCN_00218 9.4e-169 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
NECFGCCN_00219 7e-124 yijE EG EamA-like transporter family
NECFGCCN_00220 1.2e-205 gldA 1.1.1.6 C glycerol dehydrogenase
NECFGCCN_00221 2.6e-115 tal 2.2.1.2 H Belongs to the transaldolase family. Type
NECFGCCN_00222 2.3e-152 yijO K transcriptional regulator
NECFGCCN_00223 7e-121 adcA S periplasmic or secreted protein
NECFGCCN_00224 7.4e-46 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NECFGCCN_00225 2.5e-18 folE 3.5.4.16 F gtp cyclohydrolase
NECFGCCN_00226 5.9e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NECFGCCN_00227 1.7e-292 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NECFGCCN_00228 5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NECFGCCN_00230 3.3e-66 S DoxX family
NECFGCCN_00231 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NECFGCCN_00232 2.5e-186 ltaE 4.1.2.48 E Threonine aldolase
NECFGCCN_00233 4e-270 ybjT GM Epimerase dehydratase
NECFGCCN_00234 7.9e-196 ybjS 1.1.1.133, 5.1.3.13 M 3-beta hydroxysteroid dehydrogenase
NECFGCCN_00235 2e-157 amiD 3.5.1.28 V N-acetylmuramoyl-L-alanine amidase
NECFGCCN_00236 2e-192 2.7.7.65 T Diguanylate cyclase
NECFGCCN_00237 9.1e-09 yahO S Protein of unknown function (DUF1471)
NECFGCCN_00238 4.6e-91 ybjP M Induced during stationary phase and by acivicin (a glutamine analog)
NECFGCCN_00239 9.8e-132 artP E Arginine ABC transporter, ATP-binding protein
NECFGCCN_00240 5.8e-135 artI ET belongs to the bacterial solute-binding protein 3 family
NECFGCCN_00241 8.2e-115 artQ P arginine transporter permease subunit ArtQ
NECFGCCN_00242 2.6e-107 artM P (ABC) transporter
NECFGCCN_00243 2.1e-134 artJ ET belongs to the bacterial solute-binding protein 3 family
NECFGCCN_00244 1.6e-253 T PhoQ Sensor
NECFGCCN_00245 3.4e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_00246 1.3e-212 rumB 2.1.1.189, 2.1.1.190 J Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA
NECFGCCN_00247 8.7e-84 ybjO S Membrane
NECFGCCN_00248 1e-148 potI P ABC-type spermidine putrescine transport system, permease component II
NECFGCCN_00249 1.5e-175 potH P ABC-type spermidine putrescine transport system, permease component I
NECFGCCN_00250 1.6e-221 potG P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NECFGCCN_00251 3.4e-216 potF P Required for the activity of the bacterial periplasmic transport system of putrescine
NECFGCCN_00252 5e-84 ybjN S sensory transduction regulator
NECFGCCN_00253 4.6e-163 rimK 6.3.1.17, 6.3.2.32, 6.3.2.41 F Belongs to the RimK family
NECFGCCN_00254 2.2e-131 nfsA 1.5.1.38, 1.5.1.39 C Nitroreductase
NECFGCCN_00255 1.7e-42 ybjC S Protein of unknown function (DUF1418)
NECFGCCN_00256 1.8e-46 grxA 1.17.4.1 O Glutaredoxin
NECFGCCN_00257 3.8e-66 ybjM S Putative inner membrane protein of Enterobacteriaceae
NECFGCCN_00258 5.2e-301 ybjL P transport protein
NECFGCCN_00259 1.7e-94 ybjK K transcriptional regulator
NECFGCCN_00260 7.1e-212 ybjJ G Major facilitator superfamily
NECFGCCN_00261 1.2e-151 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 C Hydrolase
NECFGCCN_00262 3.2e-223 mdfA EGP multi-drug
NECFGCCN_00263 3.6e-108 ybjG 3.6.1.27 I Phosphatase
NECFGCCN_00264 1.1e-141 deoR K transcriptional
NECFGCCN_00265 2.5e-225 dacC 3.4.16.4 M Belongs to the peptidase S11 family
NECFGCCN_00266 1.4e-115 yliJ 2.5.1.18 O Glutathione S-Transferase
NECFGCCN_00267 2.9e-207 yliI G glucose sorbosone
NECFGCCN_00268 3.7e-61 bssR S disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
NECFGCCN_00269 6.8e-226 lacY G Major facilitator superfamily
NECFGCCN_00270 1.5e-258 rimO 2.8.4.4 J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
NECFGCCN_00271 5e-08 N PFAM Uncharacterised protein family UPF0150
NECFGCCN_00272 2.9e-111 serB 3.1.3.3 E phosphoserine phosphatase
NECFGCCN_00273 8.1e-255 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NECFGCCN_00274 7.1e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NECFGCCN_00275 1.7e-41 gltL 3.6.3.21 E (ABC) transporter
NECFGCCN_00276 0.0 U Hemolysin activation secretion protein
NECFGCCN_00277 9.6e-197 U Large exoproteins involved in heme utilization or adhesion
NECFGCCN_00278 6.4e-87 ybeL 1.17.4.1, 4.6.1.1 J Zinc-ribbon containing domain
NECFGCCN_00279 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NECFGCCN_00280 3.6e-84 lptE M Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
NECFGCCN_00281 4e-187 holA 2.7.7.7 L dna polymerase III delta subunit
NECFGCCN_00282 2.9e-119 nadD 2.7.7.18, 3.5.4.4, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NECFGCCN_00283 4.7e-114 cobC 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NECFGCCN_00284 5.7e-52 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NECFGCCN_00285 8.9e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NECFGCCN_00286 0.0 mrdA 3.4.16.4 M Catalyzes cross-linking of the peptidoglycan cell wall
NECFGCCN_00287 8.3e-199 mrdB M Peptidoglycan polymerase that is essential for cell wall elongation
NECFGCCN_00288 6.5e-154 rlpA M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NECFGCCN_00289 2e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NECFGCCN_00290 2.9e-41 ybeD S Belongs to the UPF0250 family
NECFGCCN_00291 4.6e-117 lipB 2.3.1.181 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
NECFGCCN_00292 4.4e-150 ybeF K transcriptional regulator
NECFGCCN_00293 2.2e-187 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NECFGCCN_00294 1.2e-18 tatE U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA
NECFGCCN_00295 5.1e-134 ybeM 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NECFGCCN_00296 1.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NECFGCCN_00297 4.3e-32 cspE K SMART Cold shock protein
NECFGCCN_00298 5.4e-100 pagP 2.3.1.251 M Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors
NECFGCCN_00299 2.8e-236 dcuC C C4-dicarboxylate
NECFGCCN_00300 4.2e-152 rna 3.1.27.1, 3.1.27.6 J Belongs to the RNase T2 family
NECFGCCN_00301 1.6e-67 rnk K regulator of nucleoside diphosphate kinase
NECFGCCN_00302 2.3e-72 uspG T Belongs to the universal stress protein A family
NECFGCCN_00303 1.3e-295 ahpF O alkyl hydroperoxide reductase
NECFGCCN_00304 1e-104 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
NECFGCCN_00305 7.2e-138 dsbG 5.3.4.1 O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NECFGCCN_00306 1.4e-159 ybdO K transcriptional regulator
NECFGCCN_00307 4.8e-248 ybdN S phosphoadenosine phosphosulfate
NECFGCCN_00308 2.6e-109 ibrB K ParB-like nuclease domain
NECFGCCN_00309 6.8e-220 ybdL 2.6.1.17, 2.6.1.88 E aminotransferase
NECFGCCN_00310 3.1e-127 mtnC 3.1.3.77 E Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NECFGCCN_00311 2.5e-103 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NECFGCCN_00312 0.0 dorA 1.7.2.3, 1.8.5.3 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_00313 9.6e-183 G (ABC) transporter
NECFGCCN_00314 4.3e-294 rbsA 3.6.3.17 P (ABC) transporter
NECFGCCN_00315 1.5e-170 alsC_1 G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_00316 5.3e-176 G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_00317 2.3e-173 ydjH 2.7.1.15 G belongs to the carbohydrate kinase PfkB family
NECFGCCN_00318 5.9e-191 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NECFGCCN_00319 1.8e-181 lyx_2 2.7.1.17, 2.7.1.189, 2.7.1.215, 2.7.1.5, 2.7.1.51 G Belongs to the FGGY kinase family
NECFGCCN_00320 1e-296 V abc transporter atp-binding protein
NECFGCCN_00321 0.0 V abc transporter atp-binding protein
NECFGCCN_00322 4.5e-187 XK27_10075 S abc transporter atp-binding protein
NECFGCCN_00324 5.8e-11
NECFGCCN_00325 1.8e-105 cfa 2.1.1.317, 2.1.1.79 M synthase
NECFGCCN_00326 1.3e-139 2.1.1.79 S Plasmid partition ParA protein
NECFGCCN_00327 1.3e-245 S NAD FAD-binding protein
NECFGCCN_00328 2.9e-128 sdh S COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_00329 4.7e-81 5.3.3.1 S transcriptional regulator
NECFGCCN_00330 1.3e-136 K Transcriptional regulator
NECFGCCN_00331 8.6e-101 blc M Outer Membrane Lipoprotein
NECFGCCN_00332 3.6e-55 ysdA K Membrane
NECFGCCN_00333 0.0 cusA P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_00334 1.2e-225 cusB M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_00335 2e-50 cusF S Copper binding periplasmic protein CusF
NECFGCCN_00336 3.8e-241 cusC M RND efflux system, outer membrane lipoprotein
NECFGCCN_00337 1.5e-121 KT Transcriptional regulatory protein, C terminal
NECFGCCN_00338 6.6e-257 cusS 2.7.13.3 T member of a two-component regulatory system
NECFGCCN_00339 2.1e-31 S Protein of unknown function (DUF1778)
NECFGCCN_00340 1.6e-62 Z012_05445 2.3.1.189 K acetyltransferase
NECFGCCN_00341 5.6e-227 ycfD 1.14.11.47 S Cupin 4 family protein
NECFGCCN_00342 2.8e-126 proV E abc transporter atp-binding protein
NECFGCCN_00343 2.1e-150 C alcohol dehydrogenase
NECFGCCN_00344 5.4e-64 mgrA K Transcriptional regulator, MarR family
NECFGCCN_00345 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NECFGCCN_00346 6.4e-41 rof K Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination
NECFGCCN_00347 7.3e-29 yaeP S Belongs to the UPF0253 family
NECFGCCN_00348 5.5e-95 yaeQ S protein conserved in bacteria
NECFGCCN_00349 2.7e-46 yaeJ J chain release factor
NECFGCCN_00350 1.4e-135 cutF MP Copper homeostasis
NECFGCCN_00351 2e-136 yaeF M cysteine-type peptidase activity
NECFGCCN_00352 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NECFGCCN_00353 2.4e-130 yaeB P PFAM Uncharacterised protein family UPF0066
NECFGCCN_00354 8.1e-67 rcsF M colanic acid biosynthetic process
NECFGCCN_00355 9.9e-149 metQ P Belongs to the NlpA lipoprotein family
NECFGCCN_00356 4e-76 metI P ABC-type metal ion transport system permease component
NECFGCCN_00357 2.1e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NECFGCCN_00358 1.8e-104 gmhB 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 6.3.2.10 E D,D-heptose 1,7-bisphosphate phosphatase
NECFGCCN_00359 3.6e-54 phoE M Belongs to the Gram-negative porin family
NECFGCCN_00360 2.7e-157 dprA LU DNA protecting protein DprA
NECFGCCN_00362 1.2e-174 yubA S permease
NECFGCCN_00363 1.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NECFGCCN_00364 1e-156 yjjH S Calcineurin-like phosphoesterase
NECFGCCN_00365 2.5e-130 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NECFGCCN_00366 0.0 pacL 3.6.3.8 P cation transport ATPase
NECFGCCN_00367 1.7e-66 ywiB S Domain of unknown function (DUF1934)
NECFGCCN_00368 5.9e-136 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
NECFGCCN_00369 7.8e-146 yidA S hydrolases of the HAD superfamily
NECFGCCN_00370 2.9e-179 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NECFGCCN_00371 1.5e-56 S Protein of unknown function (DUF454)
NECFGCCN_00372 2.7e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NECFGCCN_00373 6.2e-233 vicK 2.7.13.3 T Histidine kinase
NECFGCCN_00374 1.9e-127 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_00375 6.1e-66 rnfC C Part of a membrane complex involved in electron transport
NECFGCCN_00376 1.2e-11 rnfC C Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily
NECFGCCN_00377 1.3e-40 rnfC C Part of a membrane complex involved in electron transport
NECFGCCN_00378 1.6e-89 rnfB 1.12.98.1 C Part of a membrane complex involved in electron transport
NECFGCCN_00379 6.5e-94 rnfA C Part of a membrane complex involved in electron transport
NECFGCCN_00380 2.5e-66 ydgK S Membrane
NECFGCCN_00381 5.6e-32 cnu S positive regulation of protein complex disassembly
NECFGCCN_00382 1e-270 bglC 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_00383 2.5e-12 blr
NECFGCCN_00384 4.3e-189 ydgJ 1.1.1.371 S oxidoreductase
NECFGCCN_00385 2.2e-182 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NECFGCCN_00386 4.9e-192 ynfM_2 EGP Major facilitator Superfamily
NECFGCCN_00387 9.5e-80 yybR_1 K transcriptional regulator
NECFGCCN_00389 3.2e-89 L Transposase
NECFGCCN_00390 5.8e-174 S hydrolase
NECFGCCN_00391 0.0 U protein secretion
NECFGCCN_00392 8.4e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NECFGCCN_00393 1.9e-181 ccpA K Catabolite control protein A
NECFGCCN_00394 4.7e-191 yyaQ S YjbR
NECFGCCN_00395 9e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NECFGCCN_00396 8.7e-78 yueI S Protein of unknown function (DUF1694)
NECFGCCN_00397 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NECFGCCN_00399 2.5e-283 murE 3.4.16.4, 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NECFGCCN_00400 0.0 ftsI 3.4.16.4 M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum
NECFGCCN_00401 1.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NECFGCCN_00402 4.8e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NECFGCCN_00403 5e-81 mraZ K Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster
NECFGCCN_00404 1.2e-188 fruR 3.2.1.26 GH32 K Transcriptional
NECFGCCN_00405 3.1e-81 ilvH 2.2.1.6 E acetolactate synthase
NECFGCCN_00406 0.0 ilvI 2.2.1.6 H acetolactate synthase
NECFGCCN_00407 1.8e-178 leuO K transcriptional regulator
NECFGCCN_00408 9.7e-286 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NECFGCCN_00409 5.9e-205 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NECFGCCN_00410 5.3e-267 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NECFGCCN_00411 1.9e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NECFGCCN_00412 0.0 1.3.1.34 C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NECFGCCN_00413 3.1e-161 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD
NECFGCCN_00414 8.8e-210 ydiM G transport protein
NECFGCCN_00415 1.5e-130 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NECFGCCN_00416 4.6e-163 yybE K Transcriptional regulator
NECFGCCN_00417 2.1e-233 G transporter
NECFGCCN_00418 1e-207 setA EGP Major facilitator Superfamily
NECFGCCN_00419 4.4e-18 S Inhibitor of glucose uptake transporter SgrT
NECFGCCN_00420 0.0 sgrR K Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain
NECFGCCN_00421 1.8e-181 tbpA P thiamine ABC transporter
NECFGCCN_00422 1.3e-290 thiP P with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell
NECFGCCN_00423 7e-119 thiQ P Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NECFGCCN_00424 7.9e-124 yabI 3.6.1.27 I membrane-associated protein
NECFGCCN_00425 2.6e-168 araC K transcriptional regulator
NECFGCCN_00426 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NECFGCCN_00427 3.9e-300 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NECFGCCN_00428 5.1e-130 araD 4.1.1.104, 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 G Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate
NECFGCCN_00429 0.0 polB 2.7.7.7 L DNA polymerase
NECFGCCN_00430 0.0 rapA K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NECFGCCN_00431 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NECFGCCN_00432 2.6e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NECFGCCN_00433 8.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NECFGCCN_00434 4.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NECFGCCN_00435 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NECFGCCN_00436 5e-85 fimF NU Fimbrial protein
NECFGCCN_00437 0.0 fimD NU Usher protein
NECFGCCN_00438 5.4e-119 fimC M chaperone
NECFGCCN_00439 3.2e-95 fimI NU Fimbrial protein
NECFGCCN_00440 2.6e-84 fimA NU Fimbrial protein
NECFGCCN_00441 0.0 3.4.17.14, 3.5.1.28 NU GBS Bsp-like repeat
NECFGCCN_00442 1.5e-213 mltA GH102 M Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
NECFGCCN_00443 9.3e-147 ygdL 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NECFGCCN_00444 3.5e-68 csdE 2.8.1.7, 4.4.1.16 S cysteine desulfurase, sulfur acceptor subunit CsdE
NECFGCCN_00445 9e-223 csdA 2.8.1.7, 4.4.1.16 E Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo
NECFGCCN_00446 6.7e-34 ygdI S Lipoprotein
NECFGCCN_00447 1.3e-168 gcvA K transcriptional regulator
NECFGCCN_00448 2.5e-65 ygdD S Small membrane protein
NECFGCCN_00449 2.1e-218 rlmM 2.1.1.186 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NECFGCCN_00450 3.1e-130 fucR K transcriptional regulator
NECFGCCN_00451 1.9e-71 fucU 5.1.3.29 G Involved in the anomeric conversion of L-fucose
NECFGCCN_00452 8.3e-268 fucK 2.7.1.17, 2.7.1.189, 2.7.1.5, 2.7.1.51 F Belongs to the FGGY kinase family
NECFGCCN_00453 0.0 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
NECFGCCN_00454 6.9e-245 fucP G transporter
NECFGCCN_00455 4.7e-117 fucA 4.1.1.104, 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 G Catalyzes the cleavage of L-fuculose 1-phosphate to glycerone phosphate and L-lactaldehyde
NECFGCCN_00456 2e-211 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C alcohol dehydrogenase
NECFGCCN_00457 1.6e-140 xni 2.7.7.7 L Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment
NECFGCCN_00458 0.0 flbD T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
NECFGCCN_00459 1.8e-223 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NECFGCCN_00460 1.8e-82 S oxidoreductase
NECFGCCN_00461 5.7e-49 S oxidoreductase
NECFGCCN_00462 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NECFGCCN_00463 8.5e-145 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NECFGCCN_00465 8.6e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NECFGCCN_00466 9.9e-132 ecsA V abc transporter atp-binding protein
NECFGCCN_00467 1.9e-176 ecsB U Bacterial ABC transporter protein EcsB
NECFGCCN_00468 9.5e-55 ytmP 2.7.1.89 M Phosphotransferase
NECFGCCN_00469 2e-18 K HxlR-like helix-turn-helix
NECFGCCN_00470 2.9e-265 1.1.3.15 C Fad linked oxidase
NECFGCCN_00471 2.3e-137 P ABC-type nitrate sulfonate bicarbonate transport system permease component
NECFGCCN_00472 5e-148 P ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NECFGCCN_00473 1.4e-184 P ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NECFGCCN_00474 3.4e-171 3.5.2.10 S Creatininase
NECFGCCN_00475 1e-81 3.5.99.10 J translation initiation inhibitor, yjgF family
NECFGCCN_00476 1.1e-237 codA 3.5.4.1 F Cytosine deaminase and related metal-dependent hydrolases
NECFGCCN_00477 7.3e-175 vanB C Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1
NECFGCCN_00478 6e-163 K Transcriptional regulator
NECFGCCN_00479 8.5e-187 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NECFGCCN_00480 3.8e-133 F COG0402 Cytosine deaminase and related metal-dependent hydrolases
NECFGCCN_00481 0.0 entF 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NECFGCCN_00482 6.9e-147 fepC 3.6.3.34 HP (ABC) transporter
NECFGCCN_00483 1.9e-170 fepG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_00484 1.6e-172 fepD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_00485 1.4e-267 yfmM S abc transporter atp-binding protein
NECFGCCN_00486 1.3e-39 3.6.3.8 P cation transport ATPase
NECFGCCN_00487 1.2e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
NECFGCCN_00488 2.4e-99 K Transcriptional regulator
NECFGCCN_00489 1.6e-129 artI ET belongs to the bacterial solute-binding protein 3 family
NECFGCCN_00490 4.4e-100 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NECFGCCN_00491 1.1e-195 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NECFGCCN_00492 3.7e-179 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NECFGCCN_00493 0.0 yjeP M mechanosensitive ion channel
NECFGCCN_00494 2.6e-272 yjeM E amino acid
NECFGCCN_00495 6e-185 epmA J With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NECFGCCN_00496 0.0 frdA 1.3.5.1, 1.3.5.4 C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily
NECFGCCN_00497 1.7e-144 frdB 1.3.5.1, 1.3.5.4 C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NECFGCCN_00498 1.9e-68 frdC C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NECFGCCN_00499 3.4e-61 frdD C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NECFGCCN_00500 2.8e-99 blc M Outer Membrane Lipoprotein
NECFGCCN_00501 3e-45 sugE U multidrug resistance protein
NECFGCCN_00502 4e-16 ecnB S Entericidin EcnA/B family
NECFGCCN_00503 8.8e-104 efp J Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation
NECFGCCN_00504 1.3e-193 kamA 5.4.3.2 C lysine 2,3-aminomutase
NECFGCCN_00505 1.5e-81 K transcriptional regulator
NECFGCCN_00506 2.6e-79 NU cell adhesion
NECFGCCN_00507 1.8e-119 M Pili assembly chaperone PapD, C-terminal domain
NECFGCCN_00508 0.0 safC NU Usher protein
NECFGCCN_00509 2.4e-59 NU Fimbrial protein
NECFGCCN_00511 1.1e-162 M Secretion Protein
NECFGCCN_00512 0.0 V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NECFGCCN_00513 1.2e-133 yjeJ S YjeJ-like
NECFGCCN_00514 1.2e-58 yjeI S Membrane
NECFGCCN_00515 2e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NECFGCCN_00516 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NECFGCCN_00517 6.2e-115 uvrY K response regulator
NECFGCCN_00518 2.8e-29 yecF S Protein of unknown function (DUF2594)
NECFGCCN_00519 4.4e-132 vjbR K Transcriptional
NECFGCCN_00520 2e-132 yecC 3.6.3.21 E (ABC) transporter
NECFGCCN_00521 3.8e-114 yecS P amino acid ABC transporter
NECFGCCN_00522 8e-177 dcyD 4.4.1.15 E Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine
NECFGCCN_00523 4e-142 fliY ET Belongs to the bacterial solute-binding protein 3 family
NECFGCCN_00524 3.2e-294 amyA 3.2.1.1 GH13 G Cytoplasmic alpha-amylase
NECFGCCN_00525 1.2e-68 yedD S (Lipo)protein
NECFGCCN_00526 7.2e-107 rcsA K Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes
NECFGCCN_00527 4.1e-29 dsrB S Dextransucrase DSRB
NECFGCCN_00528 8.2e-21 yodD S Protein of unknown function (DUF2525)
NECFGCCN_00529 2.7e-302 yedQ 2.7.7.65 T Diguanylate cyclase
NECFGCCN_00530 1.9e-132 yedI S protein conserved in bacteria
NECFGCCN_00531 2.5e-156 yedA EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_00532 6.6e-87 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NECFGCCN_00533 1.6e-263 dcm 2.1.1.37 H Methyl-transferase
NECFGCCN_00534 5.2e-122 yedJ S Metal-dependent phosphohydrolase
NECFGCCN_00535 4.2e-46 yedR
NECFGCCN_00536 1.4e-212 ompS1 M Belongs to the Gram-negative porin family
NECFGCCN_00538 8.2e-148 mtfA C Belongs to the MtfA family
NECFGCCN_00539 4e-114 ET ABC transporter
NECFGCCN_00540 9.4e-136 ET Belongs to the bacterial solute-binding protein 3 family
NECFGCCN_00541 2.8e-210 arcT 2.6.1.1 E Aminotransferase
NECFGCCN_00542 6.1e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
NECFGCCN_00543 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NECFGCCN_00544 4.2e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NECFGCCN_00545 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NECFGCCN_00546 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NECFGCCN_00547 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NECFGCCN_00548 4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NECFGCCN_00549 3.1e-257 S Glucosyl transferase GtrII
NECFGCCN_00550 2.9e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NECFGCCN_00551 3.9e-221 amrA S membrane protein involved in the export of O-antigen and teichoic acid
NECFGCCN_00552 1.6e-174 M Glycosyltransferase, group 2 family protein
NECFGCCN_00553 1.2e-121 mta K Transcriptional
NECFGCCN_00554 1.4e-29 S Protein of unknown function (DUF3021)
NECFGCCN_00555 1.3e-73 K COG3279 Response regulator of the LytR AlgR family
NECFGCCN_00556 9.3e-134 cylB V ABC-2 type transporter
NECFGCCN_00557 3.2e-153 cylA V abc transporter atp-binding protein
NECFGCCN_00558 2e-149 V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NECFGCCN_00559 6.2e-39 repB S Replication regulatory protein RepB
NECFGCCN_00560 3.9e-11 repA1 S This protein is essential for plasmid replication
NECFGCCN_00561 5.3e-181 repA S IncFII RepA protein family
NECFGCCN_00562 6e-41
NECFGCCN_00563 9.3e-44 insN L silverDB
NECFGCCN_00564 4.4e-141 XK27_10035 V abc transporter atp-binding protein
NECFGCCN_00565 7.7e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NECFGCCN_00566 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NECFGCCN_00567 1.5e-33 ykzG S Belongs to the UPF0356 family
NECFGCCN_00568 9e-119 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NECFGCCN_00569 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NECFGCCN_00570 1.1e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NECFGCCN_00571 1.7e-112 azlC E AzlC protein
NECFGCCN_00572 4.4e-47 azlD S branched-chain amino acid
NECFGCCN_00573 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NECFGCCN_00574 6.1e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NECFGCCN_00575 4.8e-64 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NECFGCCN_00576 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NECFGCCN_00577 1.4e-21
NECFGCCN_00578 2.7e-32 T Phage conjugal plasmid C-4 type zinc finger protein, TraR family
NECFGCCN_00579 1.6e-30 S Domain of unknown function (DUF4222)
NECFGCCN_00580 8.1e-229 Z012_07715 L Belongs to the 'phage' integrase family
NECFGCCN_00581 1.4e-12 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NECFGCCN_00582 9.8e-97 tktB 2.2.1.1 G Transketolase
NECFGCCN_00583 1.5e-178 2.2.1.1 G Transketolase
NECFGCCN_00584 1.7e-214 rhlE 3.6.4.13 JKL DEAD-box RNA helicase involved in
NECFGCCN_00585 0.0 dinG 3.6.4.12 KL helicase
NECFGCCN_00586 3.8e-31 gluA 3.6.3.21 E (ABC) transporter
NECFGCCN_00587 2.3e-159 fliY ET ABC transporter substrate-binding protein
NECFGCCN_00588 9.3e-115 yncG 2.5.1.18 O Glutathione S-Transferase
NECFGCCN_00589 4.6e-35 pptA 5.3.2.6 S Belongs to the 4-oxalocrotonate tautomerase family
NECFGCCN_00590 1e-42 K Helix-turn-helix domain
NECFGCCN_00591 2.6e-26
NECFGCCN_00592 3.1e-255 lamB M Maltoporin (phage lambda and maltose receptor)
NECFGCCN_00593 6.6e-246 G COG2211 Na melibiose symporter and related transporters
NECFGCCN_00594 1.3e-293 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NECFGCCN_00595 3.7e-135 K transcriptional regulator
NECFGCCN_00596 3.5e-108 yddH S Flavin reductase
NECFGCCN_00598 4.7e-123 phnT 3.6.3.30 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NECFGCCN_00599 2.4e-173 ftpB P ABC transporter substrate-binding protein
NECFGCCN_00600 1.9e-284 ftpA P ABC-type Fe3 transport system permease component
NECFGCCN_00601 8.7e-164 nhoA 2.3.1.118, 2.3.1.5 Q Belongs to the arylamine N-acetyltransferase family
NECFGCCN_00602 4.2e-26 glnQ2 3.6.3.21 E (ABC) transporter
NECFGCCN_00603 7.4e-72 S Protein of unknown function (DUF1062)
NECFGCCN_00604 1.5e-57 E glyoxalase bleomycin resistance protein dioxygenase
NECFGCCN_00605 2.7e-182 cmr EGP Major facilitator Superfamily
NECFGCCN_00606 9.9e-55 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECFGCCN_00607 6.9e-207 P Major facilitator superfamily
NECFGCCN_00608 5e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
NECFGCCN_00609 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
NECFGCCN_00610 8.6e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NECFGCCN_00611 1.7e-84 yxjI S LURP-one-related
NECFGCCN_00612 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NECFGCCN_00613 8.8e-162 K sequence-specific DNA binding
NECFGCCN_00614 5.9e-09
NECFGCCN_00615 1.3e-105 K Transcriptional regulator
NECFGCCN_00616 8.2e-120 L Molecular Function DNA binding, Biological Process DNA recombination
NECFGCCN_00617 4.8e-45 L transposase activity
NECFGCCN_00618 9e-08 S Enterocin A Immunity
NECFGCCN_00619 1.4e-62 S oxidoreductase
NECFGCCN_00620 1e-173 iolE 4.2.1.44 G Xylose isomerase domain protein TIM barrel
NECFGCCN_00621 1.1e-176 K Transcriptional regulator, LacI family
NECFGCCN_00622 2.5e-41 S Protein of unknown function (DUF1778)
NECFGCCN_00623 1.2e-80 S Acetyltransferase (GNAT) domain
NECFGCCN_00625 2e-78 XK27_01265 S ECF-type riboflavin transporter, S component
NECFGCCN_00626 3.6e-141 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NECFGCCN_00627 1.6e-83 S ECF-type riboflavin transporter, S component
NECFGCCN_00629 0.0 nifJ 1.2.7.1 C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NECFGCCN_00630 1.3e-274 lpdA 1.8.1.4 C Dehydrogenase
NECFGCCN_00631 1.2e-143 S Domain of unknown function (DUF4123)
NECFGCCN_00632 0.0 S protein conserved in bacteria
NECFGCCN_00633 0.0 clpV O Belongs to the ClpA ClpB family
NECFGCCN_00634 5.7e-91 hcp S Type VI secretion system effector
NECFGCCN_00635 6e-310 M Belongs to the ompA family
NECFGCCN_00636 1.2e-51 livG E Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids
NECFGCCN_00637 5.6e-223 livM U Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_00638 2e-158 livH E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_00639 1e-212 livJ E With LivFGHM is involved in the high affinity leucine transport
NECFGCCN_00640 0.0 pflB 2.3.1.54 C formate acetyltransferase
NECFGCCN_00641 6e-219 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NECFGCCN_00642 2.8e-241 tdcC E Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system)
NECFGCCN_00643 8.8e-184 tdcB 4.3.1.15, 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NECFGCCN_00644 1.4e-170 tdcA K Transcriptional regulator
NECFGCCN_00645 4.7e-143 P ABC-type phosphate phosphonate transport system periplasmic component
NECFGCCN_00646 9e-192 I fatty acid desaturase
NECFGCCN_00647 2.5e-47 U family outer membrane protein
NECFGCCN_00648 1.8e-35 U Large exoproteins involved in heme utilization or adhesion
NECFGCCN_00651 1.5e-37 U family outer membrane protein
NECFGCCN_00652 8.3e-24 U Large exoproteins involved in heme utilization or adhesion
NECFGCCN_00653 0.0 fhaC U hemolysin activation secretion protein
NECFGCCN_00654 1.3e-114 cstA T Carbon starvation protein
NECFGCCN_00655 3.9e-136 3.5.1.32 S amidohydrolase
NECFGCCN_00656 0.0 fdhF 1.17.1.10, 1.17.1.9, 1.17.99.7 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_00657 9.5e-208 ybiC 1.5.1.21 C Belongs to the LDH2 MDH2 oxidoreductase family
NECFGCCN_00658 7.1e-203 afuA P ABC transporter substrate-binding protein
NECFGCCN_00659 2.4e-11 cysW_1 P Binding-protein-dependent transport system inner membrane component
NECFGCCN_00660 1.7e-57 cysW_1 P ABC-type Fe3 transport system permease component
NECFGCCN_00661 3e-119 E phosphoserine phosphatase
NECFGCCN_00662 5.6e-126 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NECFGCCN_00663 4.7e-87 nlpC 3.4.17.13 M lipoprotein nlpC
NECFGCCN_00664 3.4e-116 S dextransucrase activity
NECFGCCN_00665 2.8e-168 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NECFGCCN_00666 3.2e-124 ftsE D cell division ATP-binding protein FtsE
NECFGCCN_00667 2.6e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NECFGCCN_00668 2e-208 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NECFGCCN_00669 9.7e-267 nnrD 4.2.1.136, 5.1.99.6 H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NECFGCCN_00670 4.5e-82 yjeE S ATPase or kinase
NECFGCCN_00671 4.2e-221 amiB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NECFGCCN_00672 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NECFGCCN_00673 1.7e-176 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NECFGCCN_00674 1.3e-29 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NECFGCCN_00675 8e-238 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NECFGCCN_00676 1.3e-163 hflK O HflC and HflK could encode or regulate a protease
NECFGCCN_00677 8.1e-118 hflC O HflC and HflK could regulate a protease
NECFGCCN_00678 7.8e-128 mak 2.7.1.4, 2.7.1.59 GK ROK family
NECFGCCN_00679 1e-48 celC 2.7.1.196, 2.7.1.205 G PTS system, cellobiose-specific IIA component
NECFGCCN_00680 3.3e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_00681 1.4e-50 gmuB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NECFGCCN_00682 9.1e-235 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_00683 1.2e-268 lamB G maltoporin
NECFGCCN_00684 0.0 2.1.1.72, 3.1.4.46, 3.2.1.1 GH13 G Pkd domain containing protein
NECFGCCN_00685 1.3e-281 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_00686 0.0 fhlA KT transcriptional regulator
NECFGCCN_00687 0.0 ctpF P ATPase, P-type (transporting), HAD superfamily, subfamily IC
NECFGCCN_00688 5.4e-234 ybhC 3.1.1.11, 4.2.2.2 G Pectinesterase
NECFGCCN_00689 1.3e-219 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NECFGCCN_00690 2.2e-176 hutG 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NECFGCCN_00691 1e-125 hutC K histidine utilization repressor
NECFGCCN_00692 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NECFGCCN_00693 3.2e-70 dmsB C reductase chain B
NECFGCCN_00694 2e-135 ssuB2 P (ABC) transporter
NECFGCCN_00695 1.3e-182 ssuC2 P ABC-type nitrate sulfonate bicarbonate transport system permease component
NECFGCCN_00696 1.2e-191 P ABC-type nitrate sulfonate bicarbonate transport
NECFGCCN_00697 6.7e-15
NECFGCCN_00699 2.8e-68 pinE L Site-specific recombinases, DNA invertase Pin homologs
NECFGCCN_00700 1.2e-25 pinE L Site-specific recombinases, DNA invertase Pin homologs
NECFGCCN_00701 7e-182 L Belongs to the 'phage' integrase family
NECFGCCN_00702 6e-181 abgT H transporter
NECFGCCN_00703 2.1e-271 abgB 3.5.1.32 S amidohydrolase
NECFGCCN_00704 4.2e-242 abgA 3.5.1.32 S Protein involved in hydrolase activity and metabolic process
NECFGCCN_00705 2.1e-160 abgR K transcriptional regulator
NECFGCCN_00707 1.2e-127 U TraM recognition site of TraD and TraG
NECFGCCN_00709 2.3e-48 vex3 V Efflux ABC transporter, permease protein
NECFGCCN_00710 1.5e-115 K Response regulator receiver domain protein
NECFGCCN_00711 4.2e-08 bcrA V abc transporter atp-binding protein
NECFGCCN_00712 2.4e-290 V ABC transporter transmembrane region
NECFGCCN_00713 3.2e-51
NECFGCCN_00715 4.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
NECFGCCN_00716 6.4e-61 S Protein of unknown function (DUF1722)
NECFGCCN_00717 7.6e-20 S Bacterial lipoprotein
NECFGCCN_00718 7.5e-10
NECFGCCN_00719 1.4e-128 V CAAX protease self-immunity
NECFGCCN_00720 3e-45
NECFGCCN_00721 1.4e-75 K TetR family transcriptional regulator
NECFGCCN_00724 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NECFGCCN_00725 1.6e-211 XK27_05110 P Chloride transporter ClC family
NECFGCCN_00726 2.8e-39 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NECFGCCN_00727 4e-276 clcA P Chloride transporter, ClC family
NECFGCCN_00728 1e-75 fld C Flavodoxin
NECFGCCN_00729 2.2e-18 XK27_08880
NECFGCCN_00730 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
NECFGCCN_00731 2.8e-148 estA CE1 S Esterase
NECFGCCN_00732 1.3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NECFGCCN_00733 8.9e-136 XK27_08845 S abc transporter atp-binding protein
NECFGCCN_00734 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_00735 4e-176 XK27_08835 S ABC transporter substrate binding protein
NECFGCCN_00736 1.7e-18 S Domain of unknown function (DUF4649)
NECFGCCN_00737 4.2e-87 Q the current gene model (or a revised gene model) may contain a frame shift
NECFGCCN_00738 7.8e-233 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NECFGCCN_00739 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NECFGCCN_00740 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NECFGCCN_00741 6.4e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NECFGCCN_00742 4.9e-178 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
NECFGCCN_00743 1e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NECFGCCN_00744 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NECFGCCN_00745 1.8e-101 2.3.1.128 K Acetyltransferase GNAT Family
NECFGCCN_00746 2.3e-284 S Protein of unknown function (DUF3114)
NECFGCCN_00748 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NECFGCCN_00749 8.2e-18 bglC K Transcriptional regulator
NECFGCCN_00750 1.2e-242 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NECFGCCN_00751 2.9e-165 gltI ET ABC-type amino acid transport signal transduction systems periplasmic component domain
NECFGCCN_00752 5.1e-136 gltJ P amino acid ABC transporter
NECFGCCN_00753 1.2e-112 gltK P With GltJLPS and GadC for glutamate and GltJLP, DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate
NECFGCCN_00754 1.4e-19 gltL 3.6.3.21 E (ABC) transporter
NECFGCCN_00757 7.8e-154 ydgD M Belongs to the peptidase S1B family
NECFGCCN_00758 3e-51 mdtI U Catalyzes the excretion of spermidine
NECFGCCN_00759 4.2e-51 mdtJ U Catalyzes the excretion of spermidine
NECFGCCN_00760 2.7e-143 tqsA T permease
NECFGCCN_00761 2.3e-41 mdcA 2.3.1.187 I malonate decarboxylase, alpha subunit
NECFGCCN_00762 4.5e-89 K transcriptional regulator
NECFGCCN_00763 1.6e-36 yneF S UPF0154 protein
NECFGCCN_00764 7.6e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NECFGCCN_00765 2.1e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NECFGCCN_00766 8.1e-96 XK27_09740 S Phosphoesterase
NECFGCCN_00767 7.1e-86 ykuL S CBS domain
NECFGCCN_00768 3.1e-128 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NECFGCCN_00769 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NECFGCCN_00770 3.1e-96 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NECFGCCN_00771 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECFGCCN_00772 9.5e-118 nfnB 1.5.1.34 C Nitroreductase
NECFGCCN_00773 1.2e-66 ybdF S YjbR
NECFGCCN_00774 8.8e-99 K transcriptional regulator
NECFGCCN_00775 1.6e-218 romA S Zn-dependent hydrolases of the beta-lactamase fold
NECFGCCN_00776 1e-59 ramA K Transcriptional regulator
NECFGCCN_00777 5.9e-36 ybdJ S membrane
NECFGCCN_00778 1.5e-07
NECFGCCN_00779 8.2e-48 ctpF P ATPase, P-type (transporting), HAD superfamily, subfamily IC
NECFGCCN_00780 6.7e-87 ytsP 1.8.4.14 T GAF domain-containing protein
NECFGCCN_00781 1.4e-44 dsbA O Thiol disulfide interchange protein
NECFGCCN_00782 2e-157 phoH T PhoH-like protein
NECFGCCN_00783 1.9e-247 efeB P peroxidase
NECFGCCN_00784 7.4e-203 efeO P periplasmic lipoprotein involved in iron transport
NECFGCCN_00785 9.2e-126 efeU P Iron Permease
NECFGCCN_00786 8.8e-202 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NECFGCCN_00787 9.5e-74 J Protein of unknown function (DUF3574)
NECFGCCN_00788 4.2e-278 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECFGCCN_00789 0.0 putA 1.2.1.88, 1.3.8.7, 1.5.5.2 C Oxidizes proline to glutamate for use as a carbon and nitrogen source
NECFGCCN_00790 9.6e-65 S Lysozyme inhibitor LprI
NECFGCCN_00791 4.2e-110 rutR K transcriptional regulator
NECFGCCN_00792 1.3e-207 rutA 1.14.99.46 C Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate
NECFGCCN_00793 4.3e-132 rutB 3.5.1.110 Q In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2
NECFGCCN_00794 1.4e-68 rutC 3.5.99.10 J May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation
NECFGCCN_00795 2e-138 rutD I May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation
NECFGCCN_00796 1.6e-111 rutE C May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted
NECFGCCN_00797 2.2e-90 rutF 1.5.1.36 C Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway
NECFGCCN_00798 5.6e-234 rutG F Xanthine uracil
NECFGCCN_00799 5.2e-22 agrA KT response regulator
NECFGCCN_00800 2.8e-227 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NECFGCCN_00801 1.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
NECFGCCN_00802 6.3e-54 V ABC-2 family transporter protein
NECFGCCN_00804 4.6e-120 KT Transcriptional regulatory protein, C terminal
NECFGCCN_00805 1.5e-94 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NECFGCCN_00806 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NECFGCCN_00807 8.4e-159 dam 2.1.1.72 L Site-specific DNA-methyltransferase (Adenine-specific)
NECFGCCN_00808 1.7e-48 manO S Protein conserved in bacteria
NECFGCCN_00809 5.9e-158 manN G PTS system mannose fructose sorbose family IID component
NECFGCCN_00810 5.7e-133 manY G pts system
NECFGCCN_00811 6.2e-39 manL 2.7.1.191 G pts system
NECFGCCN_00812 1.9e-46 S PerC transcriptional activator
NECFGCCN_00813 1.6e-92 K Bacterial regulatory proteins, luxR family
NECFGCCN_00814 0.0 H Exports the biofilm adhesin polysaccharide poly-beta- 1,6-N-acetyl-D-glucosamine (PGA) across the outer membrane. The PGA transported seems to be partially N-deacetylated since N- deacetylation of PGA by PgaB is needed for PGA export through the PgaA porin
NECFGCCN_00815 0.0 pgaB G Polysaccharide deacetylase
NECFGCCN_00816 1e-256 pgaC GT2 M Poly-beta-1,6-N-acetyl-D-glucosamine synthase
NECFGCCN_00817 4.4e-74 pgaD S PgaD-like protein
NECFGCCN_00818 1.3e-132 O Dsba oxidoreductase
NECFGCCN_00819 2.6e-103 yoaE_3 P COG0861 Membrane protein TerC possibly involved in tellurium resistance
NECFGCCN_00820 6.5e-173 cbpA O displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity
NECFGCCN_00821 7.5e-49 cbpM K Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ
NECFGCCN_00822 7.4e-98 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NECFGCCN_00823 1.5e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NECFGCCN_00824 1.9e-23 tatA U protein secretion
NECFGCCN_00826 8.8e-212 msmX P Belongs to the ABC transporter superfamily
NECFGCCN_00827 2.2e-151 malG P ABC transporter (Permease
NECFGCCN_00828 4.8e-249 malF P ABC transporter (Permease
NECFGCCN_00829 3.9e-229 malX G ABC transporter
NECFGCCN_00830 9.4e-47 osmY_1 S Periplasmic or secreted lipoprotein
NECFGCCN_00831 2.3e-104 yqaB S Phosphatase
NECFGCCN_00832 4.7e-73 yqaA S Membrane
NECFGCCN_00833 8.7e-303 gshA 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily
NECFGCCN_00834 4.7e-96 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NECFGCCN_00835 2.3e-139 K AraC family transcriptional regulator
NECFGCCN_00836 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NECFGCCN_00837 1.2e-277 emrB EGP Major facilitator Superfamily
NECFGCCN_00838 3.6e-208 emrA V multidrug resistance efflux pump
NECFGCCN_00839 4.5e-94 mprA K Transcriptional
NECFGCCN_00840 1.9e-50 ygaH S L-valine transmembrane transporter activity
NECFGCCN_00841 6.8e-112 ygaZ E branched-chain amino acid
NECFGCCN_00842 1.4e-181 proX E glycine, betaine
NECFGCCN_00843 1.5e-168 proW P ABC-type proline glycine betaine transport system, permease component
NECFGCCN_00844 2.4e-220 proV 3.6.3.32 E glycine, betaine
NECFGCCN_00845 3.6e-182 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECFGCCN_00846 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECFGCCN_00847 1.7e-72 nrdI F Probably involved in ribonucleotide reductase function
NECFGCCN_00848 3.3e-39 nrdH O Glutaredoxin-like protein NrdH
NECFGCCN_00849 1.1e-69 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NECFGCCN_00850 6.7e-243 gabR_2 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_00851 1.1e-56 ygaM S ribosome binding
NECFGCCN_00852 7.4e-64 ygaC S Protein of unknown function (DUF2002)
NECFGCCN_00853 1.4e-75 alaE U L-alanine exporter AlaE
NECFGCCN_00855 4.9e-53 stpA S Belongs to the histone-like protein H-NS family
NECFGCCN_00856 2.2e-07
NECFGCCN_00857 4.7e-176 lpxO O Aspartyl Asparaginyl beta-hydroxylase
NECFGCCN_00858 3.6e-78 ygaP P SMART Rhodanese domain protein
NECFGCCN_00859 3.1e-47 ygaV K transcriptional regulator
NECFGCCN_00860 3.3e-101 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NECFGCCN_00861 3.5e-155 K transcriptional regulator
NECFGCCN_00862 0.0 acoR KQ transcriptional regulator
NECFGCCN_00863 5e-295 aldA 1.2.1.3 C belongs to the aldehyde dehydrogenase family
NECFGCCN_00864 3.6e-68 NU Fimbrial protein
NECFGCCN_00865 1.3e-117 NU chaperone
NECFGCCN_00866 0.0 fimD_3 NU Usher protein
NECFGCCN_00867 3.1e-190 NU Fimbrial protein
NECFGCCN_00868 2.3e-78 etfD NU Fimbrial protein
NECFGCCN_00869 3.4e-232 fimD NU Fimbrial biogenesis outer membrane usher protein
NECFGCCN_00870 2.9e-69 M chaperone
NECFGCCN_00871 1.3e-51 NU Fimbrial protein
NECFGCCN_00872 1.8e-21 rcsV K helix_turn_helix, Lux Regulon
NECFGCCN_00873 1e-135 pheC 4.2.1.51, 4.2.1.91 ET Belongs to the bacterial solute-binding protein 3 family
NECFGCCN_00874 2.1e-103
NECFGCCN_00875 1.4e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_00876 5.2e-178 ghrA 1.1.1.79, 1.1.1.81 EH D-isomer specific 2-hydroxyacid dehydrogenase
NECFGCCN_00877 1.2e-134 fucA_2 4.1.1.104, 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NECFGCCN_00878 6.3e-274 3.6.3.21 E (ABC) transporter
NECFGCCN_00879 6.1e-143 ET Amino acid ABC transporter substrate-binding protein
NECFGCCN_00880 1.5e-208 efe_1 C Belongs to the iron ascorbate-dependent oxidoreductase family
NECFGCCN_00881 2.9e-167 G Xylose isomerase
NECFGCCN_00882 1.4e-183 speB 3.5.3.11, 3.5.3.7 E Belongs to the arginase family
NECFGCCN_00883 4.2e-172 gbuR K transcriptional regulator
NECFGCCN_00884 4.7e-82 ywnA K transcriptional regulator
NECFGCCN_00885 0.0 mexF V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_00886 1.5e-211 mexE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_00887 1.6e-58 marA K sequence-specific DNA binding
NECFGCCN_00888 1.2e-104 K Flavin Reductase
NECFGCCN_00889 6.9e-164 K Transcriptional regulator
NECFGCCN_00890 5.3e-147 S nucleotidyltransferase activity
NECFGCCN_00892 3.4e-88 smpB J Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NECFGCCN_00893 3e-75 ratA I oligoketide cyclase lipid transport protein
NECFGCCN_00894 6.2e-45 rnfH S Belongs to the UPF0125 (RnfH) family
NECFGCCN_00895 8.3e-57 bamE M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NECFGCCN_00896 2.8e-307 recN L May be involved in recombinational repair of damaged DNA
NECFGCCN_00897 2.3e-167 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NECFGCCN_00898 9.2e-96 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NECFGCCN_00899 1.3e-224 yfjD P Mg2 and Co2 transporter CorB
NECFGCCN_00900 5.6e-141 ypjD S cytochrome C assembly protein
NECFGCCN_00901 1.7e-230 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components
NECFGCCN_00902 4.1e-37 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NECFGCCN_00903 7.2e-103 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NECFGCCN_00904 5.3e-144 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NECFGCCN_00905 4.2e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NECFGCCN_00906 4.5e-74 copB P Protein of unknown function (DUF2946)
NECFGCCN_00907 1.7e-246 S Iron-regulated membrane protein
NECFGCCN_00908 3e-84 yfiB M Belongs to the ompA family
NECFGCCN_00909 7.2e-220 yfiN 2.7.7.65 T Diguanylate cyclase
NECFGCCN_00910 1.3e-90 yfiR S bacterial-type flagellum-dependent swarming motility
NECFGCCN_00911 5.9e-202 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NECFGCCN_00912 4.2e-206 tyrA 1.3.1.12, 1.3.1.13, 1.3.1.43, 5.4.99.5 E T-protein
NECFGCCN_00913 1.5e-174 yvrE 3.1.1.15 G gluconolactonase
NECFGCCN_00914 2.8e-213 pheA 1.3.1.12, 2.3.1.79, 2.5.1.54, 4.2.1.51, 5.4.99.5 E chorismate mutase
NECFGCCN_00915 2.6e-55 hpf J Sigma 54 modulation protein
NECFGCCN_00916 3.5e-137 bamD GH23 M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NECFGCCN_00917 1e-184 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NECFGCCN_00918 1.2e-140 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NECFGCCN_00919 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NECFGCCN_00920 6e-258 trkH P Cation transport protein
NECFGCCN_00921 1.2e-244 trkA P Potassium transporter peripheral membrane component
NECFGCCN_00922 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NECFGCCN_00923 3.5e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NECFGCCN_00924 2.4e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NECFGCCN_00925 6e-155 K sequence-specific DNA binding
NECFGCCN_00926 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NECFGCCN_00927 3.2e-53 yhaI L Membrane
NECFGCCN_00928 8.2e-244 S Domain of unknown function (DUF4173)
NECFGCCN_00929 6.8e-95 ureI S AmiS/UreI family transporter
NECFGCCN_00930 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NECFGCCN_00931 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NECFGCCN_00932 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NECFGCCN_00933 6.6e-78 ureE O enzyme active site formation
NECFGCCN_00934 1.7e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NECFGCCN_00935 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NECFGCCN_00936 1.7e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NECFGCCN_00937 4.3e-175 cbiM P PDGLE domain
NECFGCCN_00938 7.1e-11
NECFGCCN_00939 1.2e-89 K Bacterial regulatory proteins, tetR family
NECFGCCN_00940 4.2e-164 GM NmrA-like family
NECFGCCN_00941 1.5e-163 S Beta-lactamase
NECFGCCN_00942 4.1e-167 mexT K transcriptional regulator
NECFGCCN_00943 5.8e-166 K Transcriptional regulator
NECFGCCN_00944 2.5e-87 yrdA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NECFGCCN_00945 5.7e-42 yrdB S Protein of unknown function (DUF1488)
NECFGCCN_00946 8.4e-148 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NECFGCCN_00947 3.1e-104 tsaC 2.7.7.87 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate
NECFGCCN_00948 1.3e-80 yrdD L dNA topoisomerase
NECFGCCN_00949 1.2e-82 smg S Belongs to the Smg family
NECFGCCN_00950 4.9e-199 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NECFGCCN_00951 9.2e-35
NECFGCCN_00952 1.5e-158 gcvA_4 K Transcriptional regulator, LysR family
NECFGCCN_00953 4.9e-85
NECFGCCN_00954 1.2e-128 ytnP S Beta-lactamase
NECFGCCN_00956 6.8e-72 yqeI K Transcriptional regulatory protein, C terminal
NECFGCCN_00957 4.4e-89
NECFGCCN_00958 4.8e-23 S Protein of unknown function (DUF1471)
NECFGCCN_00959 1.2e-117 cynT 4.2.1.1 P Reversible hydration of carbon dioxide
NECFGCCN_00960 1.8e-102 E threonine efflux protein
NECFGCCN_00961 2.6e-135 glpR_5 K Transcriptional Regulator, DeoR family
NECFGCCN_00962 1.3e-63 yyaH 4.4.1.5 E bleomycin resistance protein
NECFGCCN_00963 4.1e-124 cat 2.3.1.28 V This enzyme is an effector of chloramphenicol resistance in bacteria
NECFGCCN_00964 0.0 oppA5 E ABC transporter substrate-binding protein
NECFGCCN_00965 4.5e-146 ydaO E amino acid
NECFGCCN_00967 0.0 asnB 6.3.5.4 E asparagine synthase, glutamine-hydrolyzing
NECFGCCN_00968 2.2e-142 nagD G HAD-superfamily hydrolase, subfamily IIA
NECFGCCN_00969 3.2e-228 nagC 2.1.1.303 K Regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon
NECFGCCN_00970 3.4e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NECFGCCN_00971 3.2e-152 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NECFGCCN_00972 4.1e-125 nagE 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Phosphotransferase System
NECFGCCN_00973 1.5e-135 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NECFGCCN_00974 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NECFGCCN_00975 2.6e-135 citZ 2.3.3.1 C Belongs to the citrate synthase family
NECFGCCN_00976 1.7e-218 icd 1.1.1.42 C Isocitrate dehydrogenase
NECFGCCN_00977 3e-38 ptsH G phosphocarrier protein Hpr
NECFGCCN_00978 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NECFGCCN_00979 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NECFGCCN_00980 9.7e-160 XK27_05670 S Putative esterase
NECFGCCN_00981 3.5e-153 XK27_05675 S Esterase
NECFGCCN_00982 1.7e-223 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
NECFGCCN_00983 3.3e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
NECFGCCN_00984 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
NECFGCCN_00985 1.1e-214 ubiF CH ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6
NECFGCCN_00986 7.7e-274 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NECFGCCN_00987 4.8e-151 ybeZ T phosphate starvation-inducible protein PhoH
NECFGCCN_00988 3.6e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NECFGCCN_00989 3.5e-162 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NECFGCCN_00990 2.4e-100 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NECFGCCN_00991 1.5e-78 dps P Belongs to the Dps family
NECFGCCN_00992 3.4e-79 perR P Belongs to the Fur family
NECFGCCN_00993 4.2e-27 yqgQ S protein conserved in bacteria
NECFGCCN_00994 5.6e-175 glk 2.7.1.2 G Glucokinase
NECFGCCN_00995 0.0 typA T GTP-binding protein TypA
NECFGCCN_00996 7.7e-80 S CAAX amino terminal protease family protein
NECFGCCN_00997 4.9e-137 ssuC 1.14.14.5 P ABC-type nitrate sulfonate bicarbonate transport system permease component
NECFGCCN_00998 5.5e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NECFGCCN_00999 8e-174 ssuA P ABC transporter
NECFGCCN_01000 1.4e-101 ssuE 1.5.1.38 S fmn reductase
NECFGCCN_01001 6.9e-192 pyrD 1.3.1.14, 1.3.5.2 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NECFGCCN_01002 2.5e-100 zapC D Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ
NECFGCCN_01003 1.5e-211 ycbX 1.17.1.1 C Mosc domain protein beta barrel domain protein
NECFGCCN_01004 4.9e-133 rlmL 2.1.1.173, 2.1.1.191, 2.1.1.264, 2.1.1.72 J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NECFGCCN_01005 2.2e-63 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NECFGCCN_01006 4.3e-144 cof S Sucrose-6F-phosphate phosphohydrolase
NECFGCCN_01007 1.5e-130 glcR K transcriptional regulator (DeoR family)
NECFGCCN_01008 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NECFGCCN_01009 7.9e-71 K transcriptional
NECFGCCN_01010 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NECFGCCN_01011 5.1e-262 argH 4.3.2.1 E Argininosuccinate lyase
NECFGCCN_01012 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NECFGCCN_01013 2.4e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NECFGCCN_01014 7.4e-212 vex1 V Efflux ABC transporter, permease protein
NECFGCCN_01015 5.5e-197 mdcA 2.3.1.187 I Malonate decarboxylase
NECFGCCN_01016 9.8e-119 V CAAX protease self-immunity
NECFGCCN_01017 5e-145 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_01018 7.1e-133 fecE 3.6.3.34 HP ABC transporter
NECFGCCN_01019 5.5e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NECFGCCN_01020 2.1e-123 ybbA S Putative esterase
NECFGCCN_01021 3.7e-157 yegS 2.7.1.107 I Diacylglycerol kinase
NECFGCCN_01022 1.4e-221 scrA 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system sucrose-specific
NECFGCCN_01023 8.1e-284 scrB 3.2.1.26 GH32 G invertase
NECFGCCN_01024 2.1e-188 scrR 3.2.1.26 GH32 K Sucrose operon repressor
NECFGCCN_01026 9.2e-158 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NECFGCCN_01027 3e-86 ychJ S Belongs to the UPF0225 family
NECFGCCN_01028 8.9e-167 rssA M esterase of the alpha-beta hydrolase superfamily
NECFGCCN_01029 2.2e-177 T Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation
NECFGCCN_01030 4.4e-166 galU 2.7.7.9 M Utp--glucose-1-phosphate uridylyltransferase
NECFGCCN_01031 8.7e-61 hns K Belongs to the histone-like protein H-NS family
NECFGCCN_01032 2.9e-93 tdk 2.7.1.21 F thymidine kinase
NECFGCCN_01033 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NECFGCCN_01034 1.8e-108 ychE U UPF0056 membrane protein
NECFGCCN_01035 0.0 oppA E ABC transporter substrate-binding protein
NECFGCCN_01036 1.7e-152 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECFGCCN_01037 1.6e-144 oppC P COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components
NECFGCCN_01038 1.6e-188 oppD 3.6.3.24 P Belongs to the ABC transporter superfamily
NECFGCCN_01039 7.6e-191 oppF P Belongs to the ABC transporter superfamily
NECFGCCN_01040 1.1e-142 kch J COG1226 Kef-type K transport systems
NECFGCCN_01041 1.2e-57 yciU S Belongs to the UPF0263 family
NECFGCCN_01042 9.7e-280 cls 2.7.8.8 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NECFGCCN_01043 1.2e-26 yciY
NECFGCCN_01044 1.8e-97 yceI S Belongs to the UPF0312 family
NECFGCCN_01045 1.2e-46 yciI T YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the
NECFGCCN_01046 9.3e-77 tonB U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NECFGCCN_01047 8.9e-172 yniA G Fructosamine kinase
NECFGCCN_01048 2.6e-40 ydiZ S endoribonuclease activity
NECFGCCN_01049 2.1e-166 pfkB 2.7.1.11, 2.7.1.56 H belongs to the carbohydrate kinase PfkB family
NECFGCCN_01050 2.5e-138 ydiY M Salt-induced outer membrane protein
NECFGCCN_01051 5.9e-30
NECFGCCN_01052 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NECFGCCN_01053 1.2e-71 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NECFGCCN_01054 9.5e-29 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NECFGCCN_01055 2.4e-54 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NECFGCCN_01056 3.8e-187 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NECFGCCN_01057 9.7e-149 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NECFGCCN_01058 1.2e-65 K Transcriptional regulator
NECFGCCN_01060 4.8e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NECFGCCN_01061 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NECFGCCN_01062 4e-100 S CAAX amino terminal protease family protein
NECFGCCN_01064 7.3e-110 V CAAX protease self-immunity
NECFGCCN_01065 8.8e-27 lanR K sequence-specific DNA binding
NECFGCCN_01066 1.4e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NECFGCCN_01067 1.5e-175 ytxK 2.1.1.72 L DNA methylase
NECFGCCN_01068 2.4e-13 comGF U Putative Competence protein ComGF
NECFGCCN_01069 3.8e-70 comGF U Competence protein ComGF
NECFGCCN_01070 1.1e-15 NU Type II secretory pathway pseudopilin
NECFGCCN_01071 7.1e-69 cglD NU Competence protein
NECFGCCN_01072 1.1e-42 comGC U Required for transformation and DNA binding
NECFGCCN_01073 1.7e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NECFGCCN_01074 4.6e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NECFGCCN_01075 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
NECFGCCN_01076 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NECFGCCN_01077 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
NECFGCCN_01078 1.4e-105 artQ P ABC transporter (Permease
NECFGCCN_01079 7.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_01080 5.9e-09 aatB ET ABC transporter substrate-binding protein
NECFGCCN_01081 8.4e-165 VPA0243 S protein conserved in bacteria
NECFGCCN_01082 7.7e-17
NECFGCCN_01083 3.7e-157 K transcriptional regulator
NECFGCCN_01084 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NECFGCCN_01085 4.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NECFGCCN_01086 1.2e-208 atoB 2.3.1.9 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
NECFGCCN_01087 5.7e-161 hbd2 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I 3-hydroxyacyl-coa dehydrogenase
NECFGCCN_01088 6.7e-246 yxjC EG COG2610 H gluconate symporter and related permeases
NECFGCCN_01089 4.7e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_01090 3.9e-159 budR K transcriptional regulator
NECFGCCN_01091 1.9e-149 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
NECFGCCN_01092 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NECFGCCN_01093 9.7e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_01094 7.2e-66 ykkB J Acetyltransferase (GNAT) domain
NECFGCCN_01095 1.4e-34 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NECFGCCN_01096 8.1e-96 3.1.1.85 S Alpha beta hydrolase
NECFGCCN_01097 2.9e-103 yvgN S Reductase
NECFGCCN_01098 5.2e-77 ykgD K Cupin
NECFGCCN_01100 8.6e-298 O MreB/Mbl protein
NECFGCCN_01102 1.2e-114 M Pilin isopeptide linkage domain protein
NECFGCCN_01103 6.3e-102 V Psort location CytoplasmicMembrane, score
NECFGCCN_01106 5.2e-14
NECFGCCN_01107 1.2e-225 dcuS 2.7.13.3 T protein histidine kinase activity
NECFGCCN_01108 3.7e-233 2.7.13.3 T protein histidine kinase activity
NECFGCCN_01109 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NECFGCCN_01110 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NECFGCCN_01111 3.6e-126 S Protein of unknown function (DUF554)
NECFGCCN_01112 1.5e-132 ecsA_2 V abc transporter atp-binding protein
NECFGCCN_01113 8.7e-266 XK27_00765
NECFGCCN_01114 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NECFGCCN_01115 3.5e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NECFGCCN_01116 4.3e-58 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NECFGCCN_01117 2e-263 adhB C Cytochrome c
NECFGCCN_01118 0.0 1.1.99.3 E Choline dehydrogenase and related flavoproteins
NECFGCCN_01119 4.5e-140 1.1.99.3 S Gluconate 2-dehydrogenase
NECFGCCN_01120 8.4e-63 E glyoxalase bleomycin resistance protein dioxygenase
NECFGCCN_01121 3.2e-95 potA_1 3.6.3.30 P Belongs to the ABC transporter superfamily
NECFGCCN_01122 1.8e-40 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_01123 3.3e-38 L HTH-like domain
NECFGCCN_01124 2.5e-12 S Cobalamin synthesis protein cobW C-terminal domain
NECFGCCN_01125 7e-46 nifJ 1.2.7.1 C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NECFGCCN_01126 6.9e-98 nifJ 1.2.7.1 C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NECFGCCN_01127 6e-39 ydbJ S Lipoprotein
NECFGCCN_01128 1.6e-73 hslJ O Heat shock protein
NECFGCCN_01129 1.6e-185 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NECFGCCN_01130 2e-75 dedA 3.6.1.27 S FtsZ-dependent cytokinesis
NECFGCCN_01131 1.3e-294 yfiB1 V abc transporter atp-binding protein
NECFGCCN_01132 1.4e-108 pvaA M lytic transglycosylase activity
NECFGCCN_01133 5.9e-48 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NECFGCCN_01134 7.1e-38 ysdA L Membrane
NECFGCCN_01135 3.6e-188 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NECFGCCN_01136 5.5e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NECFGCCN_01137 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NECFGCCN_01138 1.2e-45 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NECFGCCN_01139 1.5e-34
NECFGCCN_01140 5.4e-33 S Protein of unknown function (DUF1648)
NECFGCCN_01141 3.8e-114 P FtsX-like permease family
NECFGCCN_01142 1.2e-24 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NECFGCCN_01143 1.5e-203 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NECFGCCN_01144 1.1e-102 zipA D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins
NECFGCCN_01145 7.6e-143 cysZ U High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
NECFGCCN_01146 4.3e-175 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NECFGCCN_01147 1.1e-37 ptsH G Phosphocarrier protein Hpr
NECFGCCN_01148 0.0 ptsI 2.7.1.121, 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NECFGCCN_01149 6.7e-87 crr G pts system
NECFGCCN_01150 2.2e-35
NECFGCCN_01151 3e-143 pdxK 2.7.1.35 H Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NECFGCCN_01152 4.2e-234 ptsJ K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_01153 7.1e-68 yybH S SnoaL-like domain
NECFGCCN_01154 1e-165 cysM 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NECFGCCN_01155 9.1e-206 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NECFGCCN_01156 1.5e-158 cysW P (ABC) transporter
NECFGCCN_01157 4e-145 cysT P sulfate ABC transporter
NECFGCCN_01158 5.3e-192 cysP P Thiosulfate transporter subunit
NECFGCCN_01159 1.5e-169 yfeX P peroxidase
NECFGCCN_01160 2.6e-103 yfeY S Protein of unknown function (DUF1131)
NECFGCCN_01161 1.6e-79 yfeZ S Protein of unknown function (DUF2919)
NECFGCCN_01162 2.4e-77 ypeA K Belongs to the acetyltransferase family. YpeA subfamily
NECFGCCN_01163 4.4e-155 amiA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NECFGCCN_01164 1.4e-180 hemF 1.3.3.3 H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX
NECFGCCN_01165 3.8e-201 eutR K transcriptional regulator
NECFGCCN_01166 6.9e-73 eutK CQ ethanolamine utilization protein
NECFGCCN_01167 1.4e-113 eutL E Carboxysome structural protein involved in ethanolamine utilization
NECFGCCN_01168 1.1e-143 eutC 4.3.1.7 E Belongs to the EutC family
NECFGCCN_01169 1.6e-260 eutB 4.3.1.7 E With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine
NECFGCCN_01170 4.1e-251 eutA E ethanolamine utilization protein
NECFGCCN_01171 1.6e-219 eutH E ethanolamine utilization protein
NECFGCCN_01172 2e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NECFGCCN_01173 3e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NECFGCCN_01174 2.9e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NECFGCCN_01175 3.5e-164 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NECFGCCN_01176 6.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NECFGCCN_01177 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NECFGCCN_01178 9.6e-245 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NECFGCCN_01179 1.2e-94 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NECFGCCN_01180 2.1e-23
NECFGCCN_01181 5.2e-110 ugpC P Belongs to the ABC transporter superfamily
NECFGCCN_01182 1.2e-246 yesO G ABC transporter substrate-binding protein
NECFGCCN_01183 5.5e-245 rafY S Porin-like glycoporin RafY
NECFGCCN_01184 2.2e-292 cscA 3.2.1.26 GH32 G invertase
NECFGCCN_01185 4.7e-227 lacY_2 P Major facilitator superfamily
NECFGCCN_01186 1.8e-184 cscR K Transcriptional
NECFGCCN_01187 5.9e-258 araE EGP Major facilitator Superfamily
NECFGCCN_01188 7.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_01189 3.7e-237 ogl 4.2.2.6 U oligogalacturonate lyase
NECFGCCN_01190 1.4e-132 lptD M oligogalacturonate-specific porin
NECFGCCN_01191 6.2e-12 G mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
NECFGCCN_01192 3.6e-32 yhcA V abc transporter atp-binding protein
NECFGCCN_01193 8.1e-133 E PFAM secretory lipase
NECFGCCN_01194 1.6e-48 evgA 3.1.4.52 T helix_turn_helix, Lux Regulon
NECFGCCN_01195 2e-55 S Fusaric acid resistance protein-like
NECFGCCN_01196 0.0 evgS 2.7.13.3 T PhoQ Sensor
NECFGCCN_01197 2.3e-52 evgA 3.1.4.52 K response regulator
NECFGCCN_01198 7.9e-19
NECFGCCN_01199 1.7e-75 M Pili assembly chaperone PapD, C-terminal domain
NECFGCCN_01200 9.9e-12 NU Fimbrial protein
NECFGCCN_01201 4.3e-47 NU Fimbrial protein
NECFGCCN_01202 4.1e-85 M Pili assembly chaperone PapD, C-terminal domain
NECFGCCN_01203 9.3e-85 M Pili assembly chaperone PapD, C-terminal domain
NECFGCCN_01204 0.0 fimD_3 NU outer membrane usher protein
NECFGCCN_01206 5.3e-36
NECFGCCN_01207 3.6e-112 pagO EG EamA-like transporter family
NECFGCCN_01208 3.3e-31 hdeA M Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non- specifically the aggregation of denaturated periplasmic proteins
NECFGCCN_01209 5.6e-77 dppF 3.6.3.30 EP abc transporter atp-binding protein
NECFGCCN_01210 7.9e-106 oppD P abc transporter atp-binding protein
NECFGCCN_01211 4.6e-122 dppC P ABC transporter (permease)
NECFGCCN_01212 1.4e-152 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECFGCCN_01213 5.3e-255 appA_2 E ABC transporter substrate-binding protein
NECFGCCN_01214 2.8e-129 yut E urea transporter
NECFGCCN_01215 6.6e-104 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NECFGCCN_01216 1.8e-102 ureG F Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NECFGCCN_01217 4.5e-73 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NECFGCCN_01218 3.6e-53 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NECFGCCN_01219 7.6e-300 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NECFGCCN_01220 1e-43 ureB 3.5.1.5 E Urease beta subunit
NECFGCCN_01221 6.7e-42 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NECFGCCN_01222 2.4e-194 P Psort location CytoplasmicMembrane, score 10.00
NECFGCCN_01223 2e-20 hdeB M Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins
NECFGCCN_01224 4.4e-29 hdeD S Acid-resistance membrane protein
NECFGCCN_01225 5.6e-246 emrY P Fungal trichothecene efflux pump (TRI12)
NECFGCCN_01226 3.5e-83 emrA V HlyD membrane-fusion protein of T1SS
NECFGCCN_01227 1.6e-90 evgA 3.1.4.52 T helix_turn_helix, Lux Regulon
NECFGCCN_01228 1e-138 evgS 2.7.13.3 T PhoQ Sensor
NECFGCCN_01229 1.4e-45 ccrB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NECFGCCN_01230 6.7e-47 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NECFGCCN_01231 8.9e-56
NECFGCCN_01232 5.2e-19 ttgC MU CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)
NECFGCCN_01233 4.5e-142 ycgG T EAL domain
NECFGCCN_01234 6.7e-36 lgrD Q Polysaccharide biosynthesis protein
NECFGCCN_01235 1.2e-133 4.1.1.44 S decarboxylase
NECFGCCN_01236 3.2e-50 C Aldo keto reductase
NECFGCCN_01237 5.8e-112 C Aldo keto reductase
NECFGCCN_01238 5.3e-93 kefF S Flavodoxin-like fold
NECFGCCN_01239 4.1e-55 S Protein conserved in bacteria
NECFGCCN_01240 7.3e-161 Z012_07430 K Transcriptional regulator
NECFGCCN_01242 1.9e-109 S Protein of unknown function (DUF1349)
NECFGCCN_01243 2.2e-42 S protein conserved in bacteria
NECFGCCN_01244 1e-51 arsR K transcriptional regulator
NECFGCCN_01245 5.3e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NECFGCCN_01246 9.6e-71 arsC 1.20.4.1 P arsenate reductase
NECFGCCN_01247 1e-287 dtpT U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_01248 1.4e-47 yoaC S Domain of unknown function (DUF1889)
NECFGCCN_01249 2.2e-255 mdtP MU RND efflux system, outer membrane lipoprotein
NECFGCCN_01250 0.0 mdtO S Resistance protein
NECFGCCN_01251 7.5e-178 mdtN V multidrug resistance
NECFGCCN_01252 4.2e-43 ytcA S Uncharacterised protein family
NECFGCCN_01253 4.5e-38 yjdI 1.6.3.4 S Divergent 4Fe-4S mono-cluster
NECFGCCN_01254 3.4e-45 yjdJ S GCN5-related N-acetyl-transferase
NECFGCCN_01255 1.2e-245 T EAL domain
NECFGCCN_01256 4.6e-163 fimH NU Fimbrial protein
NECFGCCN_01257 2.7e-149 ydaM 2.7.7.65 T Diguanylate cyclase
NECFGCCN_01258 1.3e-254 guaD 3.5.4.3 F Guanine deaminase
NECFGCCN_01259 3.7e-235 pucI FH uracil, thiamine, allantoin
NECFGCCN_01260 2.6e-160 ulaE 5.1.3.22 G 3-epimerase
NECFGCCN_01261 4.5e-126 ulaF 4.1.1.104, 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 G Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate
NECFGCCN_01262 1.2e-211 yajR_1 EGP Major facilitator Superfamily
NECFGCCN_01263 8e-42 yjfY S Protein of unknown function (DUF1471)
NECFGCCN_01264 1e-66 rpsF 4.3.1.19 J Binds together with S18 to 16S ribosomal RNA
NECFGCCN_01265 3.6e-54 priB L Binds single-stranded DNA at the primosome assembly site (PAS)
NECFGCCN_01266 1.3e-34 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NECFGCCN_01267 3e-70 rplI J Binds to the 23S rRNA
NECFGCCN_01268 9.8e-94 ytfB M Opacity-associated protein A
NECFGCCN_01269 2.1e-111 fklB 5.2.1.8 G Peptidyl-prolyl cis-trans
NECFGCCN_01270 4.6e-255 cycA E amino acid
NECFGCCN_01271 1.2e-120 ytfE D Di-iron-containing protein involved in the repair of iron-sulfur clusters
NECFGCCN_01272 2.9e-179 ytfF EG Permeases of the drug metabolite transporter (DMT) superfamily
NECFGCCN_01273 1.2e-157 K transcriptional regulator
NECFGCCN_01274 2e-144 ytfG 1.6.5.2 GM NmrA family
NECFGCCN_01275 1.4e-62 ytfH K Transcriptional regulator
NECFGCCN_01276 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NECFGCCN_01277 1.7e-139 cysQ 3.1.3.7 P 3'(2'),5'-bisphosphate nucleotidase
NECFGCCN_01278 6.7e-96 ytfJ S transcriptional regulator
NECFGCCN_01279 1.2e-29 ytfK S Protein of unknown function (DUF1107)
NECFGCCN_01280 6.2e-173 araC_3 K regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose
NECFGCCN_01281 0.0 lacZ3 3.2.1.23 G beta-galactosidase
NECFGCCN_01282 1.3e-229 P Major facilitator superfamily
NECFGCCN_01283 4.2e-221 ytfL P Hemolysins and related proteins containing CBS domains
NECFGCCN_01284 1.6e-122 msrA 1.8.4.11 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NECFGCCN_01285 0.0 ytfM M COG0729 Outer membrane protein
NECFGCCN_01286 0.0 ytfN M protein conserved in bacteria
NECFGCCN_01287 2.1e-63 ytfP S AIG2 family
NECFGCCN_01288 3.8e-25
NECFGCCN_01289 1.4e-98 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NECFGCCN_01290 4.8e-171 ytfQ G Periplasmic binding protein LacI transcriptional regulator
NECFGCCN_01291 1.4e-281 ytfR 3.6.3.17 P import. Responsible for energy coupling to the transport system
NECFGCCN_01292 4.7e-172 ytfT G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_01293 9.8e-175 yjfF G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_01294 4.9e-190 fbp 3.1.3.11 G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NECFGCCN_01295 2.4e-272 murC 6.3.2.4, 6.3.2.45, 6.3.2.8 M Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate
NECFGCCN_01296 2.4e-95 2.3.1.128 K Acetyltransferase GNAT Family
NECFGCCN_01297 3.1e-231 IV02_08475 G Thioredoxin
NECFGCCN_01298 1.4e-95 H ergothioneine biosynthetic process
NECFGCCN_01299 1.3e-99 PP2730 S Protein of unknown function (DUF3833)
NECFGCCN_01300 5.3e-186 ybgA S Conserved Protein
NECFGCCN_01301 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NECFGCCN_01302 4.5e-36 ylqC L Belongs to the UPF0109 family
NECFGCCN_01303 9.7e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NECFGCCN_01304 4.5e-52 higA-2 K Helix-turn-helix domain
NECFGCCN_01305 1.2e-58 S RelE family toxin-antitoxin system
NECFGCCN_01306 6.4e-205 nepI EGP Major facilitator Superfamily
NECFGCCN_01307 6.4e-148 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 S Belongs to the HAD-like hydrolase superfamily. PhnX family
NECFGCCN_01308 2.8e-210 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 H Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NECFGCCN_01309 1.1e-135 phnR K UTRA
NECFGCCN_01310 2.1e-188 phnS P Bacterial extracellular solute-binding protein
NECFGCCN_01311 1.4e-206 phnT P Belongs to the ABC transporter superfamily
NECFGCCN_01312 2.4e-145 phnU P Binding-protein-dependent transport system inner membrane component
NECFGCCN_01313 4.2e-136 phnV P TIGRFAM 2-aminoethylphosphonate ABC transport system, membrane component PhnV
NECFGCCN_01314 1.5e-280 xylB 2.7.1.17, 2.7.1.189, 2.7.1.5, 2.7.1.51 G xylulose kinase
NECFGCCN_01315 1.6e-263 mtlD 1.1.1.11, 1.1.1.17, 1.1.1.57, 1.1.1.58 G Belongs to the mannitol dehydrogenase family
NECFGCCN_01316 5.8e-177 smoC K transcriptional regulator
NECFGCCN_01317 8.4e-174 3.2.1.26 GH32 K transcriptional regulator
NECFGCCN_01318 5.9e-132 rbtD 1.1.1.56 S COG4221 Short-chain alcohol dehydrogenase of
NECFGCCN_01319 2.6e-278 rtlK 2.7.1.47 C Belongs to the ribulokinase family
NECFGCCN_01320 8.9e-57 EGP Major facilitator superfamily
NECFGCCN_01322 1.7e-211 2.7.13.3 T protein histidine kinase activity
NECFGCCN_01324 1.3e-100 agrA KT phosphorelay signal transduction system
NECFGCCN_01325 1.4e-09
NECFGCCN_01326 2.2e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NECFGCCN_01327 2.4e-30 yozG K Transcriptional regulator
NECFGCCN_01331 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NECFGCCN_01332 1.2e-181 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NECFGCCN_01333 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NECFGCCN_01334 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NECFGCCN_01335 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NECFGCCN_01336 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NECFGCCN_01338 3.7e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NECFGCCN_01339 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NECFGCCN_01340 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NECFGCCN_01341 2.6e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
NECFGCCN_01342 7.5e-180 scrR K Transcriptional regulator
NECFGCCN_01343 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NECFGCCN_01344 1.7e-61 yqhY S protein conserved in bacteria
NECFGCCN_01345 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NECFGCCN_01346 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
NECFGCCN_01347 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NECFGCCN_01349 9.5e-33 blpT
NECFGCCN_01352 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NECFGCCN_01353 4.2e-167 corA P COG0598 Mg2 and Co2 transporters
NECFGCCN_01354 8.5e-122 XK27_01040 S Protein of unknown function (DUF1129)
NECFGCCN_01356 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NECFGCCN_01357 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NECFGCCN_01358 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NECFGCCN_01360 8.1e-157 K Helix-turn-helix XRE-family like proteins
NECFGCCN_01361 1.2e-278 V ABC transporter transmembrane region
NECFGCCN_01362 3.3e-17 lacL 3.2.1.23 G -beta-galactosidase
NECFGCCN_01363 1.5e-48 lacL 3.2.1.23 G -beta-galactosidase
NECFGCCN_01364 3.7e-47 lacL 3.2.1.23 G -beta-galactosidase
NECFGCCN_01365 0.0 lacS G transporter
NECFGCCN_01366 7.5e-177 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NECFGCCN_01367 4.5e-64 S dextransucrase activity
NECFGCCN_01368 3.8e-117 M Pili assembly chaperone PapD, C-terminal domain
NECFGCCN_01369 5e-91 NU COG3539 P pilus assembly protein, pilin FimA
NECFGCCN_01370 3.2e-113 K response regulator
NECFGCCN_01372 1.8e-248 gltA 2.3.3.1 H Belongs to the citrate synthase family
NECFGCCN_01373 3.9e-23
NECFGCCN_01374 7.2e-68 hiuH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NECFGCCN_01375 3.1e-28 T Sh3 type 3 domain protein
NECFGCCN_01376 7.2e-62 manO S protein conserved in bacteria
NECFGCCN_01377 1.5e-228 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NECFGCCN_01378 1.2e-101
NECFGCCN_01379 9.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NECFGCCN_01380 1.3e-165 dnaI L Primosomal protein DnaI
NECFGCCN_01381 5.9e-211 dnaB L Replication initiation and membrane attachment
NECFGCCN_01382 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NECFGCCN_01383 7.6e-261 T PhoQ Sensor
NECFGCCN_01384 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
NECFGCCN_01385 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NECFGCCN_01386 3.5e-202 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NECFGCCN_01387 8.1e-249 glpT G transporter
NECFGCCN_01388 3.8e-309 glpA 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NECFGCCN_01389 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
NECFGCCN_01390 2.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
NECFGCCN_01391 2.3e-125 K transcriptional regulator, MerR family
NECFGCCN_01392 0.0 V ABC transporter (Permease
NECFGCCN_01393 2.6e-123 acrB V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_01394 2.2e-72 yjdL U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_01395 0.0 cadA 4.1.1.17, 4.1.1.18, 4.1.1.19 E decarboxylase
NECFGCCN_01396 3.9e-243 cadB E antiporter
NECFGCCN_01397 3.8e-266 cadC K transcriptional
NECFGCCN_01398 3.5e-42 S Protein of unknown function (DUF1471)
NECFGCCN_01399 3.9e-178 lpxL 2.3.1.241, 2.3.1.242, 2.3.1.243 M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)
NECFGCCN_01400 4.3e-166 S acetyltransferase
NECFGCCN_01401 4.4e-194 NU cell adhesion
NECFGCCN_01402 0.0 Z012_00755 NU Usher protein
NECFGCCN_01403 1.6e-191 rsmC 2.1.1.172, 2.1.1.174 J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle
NECFGCCN_01404 7.7e-73 holD 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
NECFGCCN_01405 3.7e-73 rimI 2.3.1.128, 2.3.1.234 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NECFGCCN_01406 4.1e-124 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-superfamily hydrolase, subfamily IA, variant 3
NECFGCCN_01407 6.3e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NECFGCCN_01408 3.9e-97 osmY S Periplasmic or secreted lipoprotein
NECFGCCN_01409 1.6e-18 ytjA S UPF0391 membrane protein
NECFGCCN_01410 6.9e-40 cah 4.2.1.1 P carbonic anhydrase
NECFGCCN_01411 9e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECFGCCN_01413 1.2e-29 K Helix-turn-helix XRE-family like proteins
NECFGCCN_01414 1.6e-50 S Toxin-antitoxin system, toxin component, RelE family
NECFGCCN_01415 0.0 3.2.1.25 G Belongs to the glycosyl hydrolase 2 family
NECFGCCN_01416 3.8e-27 3.2.1.25 G Belongs to the glycosyl hydrolase 2 family
NECFGCCN_01417 2.5e-158 akr5f S reductase
NECFGCCN_01418 1.3e-152 opdE EGP Major facilitator Superfamily
NECFGCCN_01419 1.9e-192 S Hydrolases of the alpha beta superfamily
NECFGCCN_01420 7.9e-152 K Transcriptional regulator
NECFGCCN_01421 2e-32
NECFGCCN_01422 7.7e-67 E lactoylglutathione lyase activity
NECFGCCN_01423 0.0 mppA E ABC transporter substrate-binding protein
NECFGCCN_01424 1.5e-137 mpaA E Murein peptide amidase A
NECFGCCN_01425 2.8e-174 ycjG 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NECFGCCN_01426 2.8e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NECFGCCN_01427 1.4e-176 abrB S Ammonia monooxygenase
NECFGCCN_01428 2.1e-293 tyrR K Transcriptional regulator of aromatic amino acids metabolism
NECFGCCN_01429 2.1e-217 celF 3.2.1.86 GT4 G Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate
NECFGCCN_01430 5.8e-134 K transcriptional regulator
NECFGCCN_01431 2.2e-67 ycjF S UPF0283 membrane protein
NECFGCCN_01435 8.2e-193 purR K Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression
NECFGCCN_01436 4.3e-178 ydhB K Transcriptional regulator
NECFGCCN_01437 1.8e-207 ydhC EGP Member of the major facilitator superfamily (MFS)
NECFGCCN_01438 1.2e-229 cfa 2.1.1.317, 2.1.1.79 M synthase
NECFGCCN_01439 1.2e-112 ribE 2.5.1.9 H Riboflavin synthase
NECFGCCN_01440 9.6e-229 mdtK V Multidrug efflux pump
NECFGCCN_01441 2.4e-136 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NECFGCCN_01442 5.9e-35 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NECFGCCN_01443 4e-43 S Sugar efflux transporter for intercellular exchange
NECFGCCN_01446 3e-102
NECFGCCN_01448 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NECFGCCN_01449 1e-43 yoeB S Addiction module toxin, Txe YoeB family
NECFGCCN_01450 7.8e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NECFGCCN_01451 1e-201 ylbM S Belongs to the UPF0348 family
NECFGCCN_01452 4.9e-139 yqeM Q Methyltransferase domain protein
NECFGCCN_01453 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NECFGCCN_01454 2.5e-86 entB 3.5.1.19 Q Isochorismatase family
NECFGCCN_01455 5.8e-106 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NECFGCCN_01456 1e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NECFGCCN_01457 7.7e-49 yhbY J RNA-binding protein
NECFGCCN_01458 1.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NECFGCCN_01459 3e-98 yqeG S hydrolase of the HAD superfamily
NECFGCCN_01460 4.1e-127 arnC M group 2 family protein
NECFGCCN_01461 8.2e-120 liaI S membrane
NECFGCCN_01462 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
NECFGCCN_01463 1.7e-296 KT response to antibiotic
NECFGCCN_01464 1.4e-98 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NECFGCCN_01465 8.6e-213 P Major facilitator superfamily
NECFGCCN_01466 2.8e-196 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NECFGCCN_01467 1.1e-175 S Domain of unknown function (DUF1852)
NECFGCCN_01469 1.8e-187 phoH T phosphate starvation-inducible protein PhoH
NECFGCCN_01473 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NECFGCCN_01474 5.2e-161 S reductase
NECFGCCN_01475 4e-107 K transcriptional regulator (lysR family)
NECFGCCN_01477 1.6e-271 cioA 1.10.3.14 C oxidase, subunit
NECFGCCN_01478 8.2e-165 katN P Mn-containing catalase
NECFGCCN_01479 2.5e-86 yciE S protein conserved in bacteria
NECFGCCN_01480 2.1e-77 yciF S protein conserved in bacteria
NECFGCCN_01483 9.5e-233 ybdR 1.1.1.14 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NECFGCCN_01484 2.6e-38 MA20_39405 S protein conserved in bacteria
NECFGCCN_01485 3.4e-52 yqjZ S Antibiotic biosynthesis monooxygenase
NECFGCCN_01486 1.6e-53 M domain protein
NECFGCCN_01487 7.7e-123 K DNA-binding helix-turn-helix protein
NECFGCCN_01488 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NECFGCCN_01489 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
NECFGCCN_01490 1.5e-70 gloA 4.4.1.5 E Lactoylglutathione lyase
NECFGCCN_01491 2.7e-227 sufS 2.8.1.7, 4.4.1.16 E Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo
NECFGCCN_01492 4.2e-71 sufE 2.8.1.7, 4.4.1.16 S PFAM Fe-S metabolism associated SufE
NECFGCCN_01493 1.8e-176 ycfS M ErfK YbiS YcfS YnhG family protein
NECFGCCN_01494 1.3e-16 lpp M Lipoprotein leucine-zipper
NECFGCCN_01495 1.2e-258 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NECFGCCN_01496 2e-29 ydhZ S fumarate hydratase activity
NECFGCCN_01497 2.4e-110 nicS K transcriptional regulator
NECFGCCN_01498 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NECFGCCN_01499 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
NECFGCCN_01500 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NECFGCCN_01501 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NECFGCCN_01502 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
NECFGCCN_01503 1.4e-57 asp S cog cog1302
NECFGCCN_01504 3.3e-223 norN V Mate efflux family protein
NECFGCCN_01505 2.8e-274 thrC 4.2.3.1 E Threonine synthase
NECFGCCN_01508 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NECFGCCN_01509 0.0 pepO 3.4.24.71 O Peptidase family M13
NECFGCCN_01510 2.5e-258 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NECFGCCN_01511 1.5e-95 ywlG S Belongs to the UPF0340 family
NECFGCCN_01514 1.4e-179 bioF 2.3.1.47, 2.8.1.6 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NECFGCCN_01515 1.9e-130 bioC 2.1.1.197 H Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
NECFGCCN_01516 2e-121 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NECFGCCN_01517 7.5e-132 urtE E ABC transporter ATP-binding protein
NECFGCCN_01518 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NECFGCCN_01520 3.3e-192 basS 2.7.13.3 T Sensor protein basS
NECFGCCN_01521 1.4e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_01522 8.3e-296 eptA 2.7.8.42, 2.7.8.43 S membrane-associated metal-dependent hydrolase
NECFGCCN_01523 1.7e-162 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NECFGCCN_01524 1e-190 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NECFGCCN_01525 1.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NECFGCCN_01526 2.2e-82 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NECFGCCN_01527 2.2e-35 moaD 2.7.7.77, 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NECFGCCN_01528 1.4e-80 moaE 2.8.1.12 H Molybdopterin converting factor, large subunit
NECFGCCN_01529 1.6e-118 ybhL S Belongs to the BI1 family
NECFGCCN_01530 2.5e-138 2.4.2.3 F Phosphorylase superfamily
NECFGCCN_01531 5.2e-44 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NECFGCCN_01533 1.6e-15 L Transposase, IS605 OrfB family
NECFGCCN_01534 2.2e-101
NECFGCCN_01536 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NECFGCCN_01537 1.6e-132 parB K Belongs to the ParB family
NECFGCCN_01538 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NECFGCCN_01539 4e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NECFGCCN_01540 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NECFGCCN_01541 2.8e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NECFGCCN_01543 3.2e-112 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NECFGCCN_01544 2.7e-123 dnaD
NECFGCCN_01545 6.7e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NECFGCCN_01546 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NECFGCCN_01547 2.4e-104 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NECFGCCN_01548 7.2e-89 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
NECFGCCN_01549 2.5e-77 urtC E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_01550 5.5e-144 urtD E abc transporter atp-binding protein
NECFGCCN_01551 5.4e-127 urtE E ABC transporter ATP-binding protein
NECFGCCN_01552 4.4e-80 K Transcriptional
NECFGCCN_01553 1.6e-208 ydeE EGP Major facilitator Superfamily
NECFGCCN_01554 2.1e-152 eamA EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_01555 2.5e-30 marB S Multiple antibiotic resistance
NECFGCCN_01556 1.8e-65 marA K Transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype
NECFGCCN_01557 5e-75 marR K transcriptional regulator
NECFGCCN_01559 3.4e-115 marC U UPF0056 membrane protein
NECFGCCN_01560 9.3e-204 sotB EGP Major facilitator Superfamily
NECFGCCN_01561 3.3e-25 yddE S phenazine biosynthesis protein PhzF
NECFGCCN_01562 1.1e-81 yfnA E amino acid
NECFGCCN_01563 6.8e-51 XK27_01300 S ASCH
NECFGCCN_01564 3.7e-24 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NECFGCCN_01565 2.5e-66 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NECFGCCN_01566 8.5e-63 glnR K Transcriptional regulator
NECFGCCN_01567 2.5e-86 S Fusaric acid resistance protein-like
NECFGCCN_01568 1.7e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NECFGCCN_01569 2.4e-114
NECFGCCN_01570 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
NECFGCCN_01571 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NECFGCCN_01572 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NECFGCCN_01573 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NECFGCCN_01574 4e-142 purR 2.4.2.7 F operon repressor
NECFGCCN_01575 2.2e-176 cbf S 3'-5' exoribonuclease yhaM
NECFGCCN_01576 6.3e-147 rmuC S RmuC domain protein
NECFGCCN_01577 2.8e-102 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NECFGCCN_01578 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NECFGCCN_01580 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NECFGCCN_01582 1.6e-68 K LytTr DNA-binding domain
NECFGCCN_01583 2.5e-77 S Protein of unknown function (DUF3021)
NECFGCCN_01584 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NECFGCCN_01585 3.4e-53 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NECFGCCN_01586 3.4e-68 argR K Regulates arginine biosynthesis genes
NECFGCCN_01587 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NECFGCCN_01588 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NECFGCCN_01589 1.9e-33
NECFGCCN_01590 2.8e-217 L Reverse transcriptase (RNA-dependent DNA polymerase)
NECFGCCN_01591 5.2e-198 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NECFGCCN_01592 9.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NECFGCCN_01593 2.7e-238 purD 6.3.4.13 F Belongs to the GARS family
NECFGCCN_01594 2.1e-20 D Plasmid stabilization system
NECFGCCN_01595 3.3e-14 XK27_10545
NECFGCCN_01596 1.5e-155 S CHAP domain
NECFGCCN_01597 3.2e-101 S abc transporter atp-binding protein
NECFGCCN_01598 4.7e-25 M Right handed beta helix region
NECFGCCN_01599 9.4e-77 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
NECFGCCN_01600 8.9e-152 galR K Transcriptional regulator
NECFGCCN_01601 1e-57 yqeF 2.3.1.9 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
NECFGCCN_01602 1.2e-155 allS_3 K Transcriptional regulator
NECFGCCN_01603 4.1e-75 YPO2978 S PFAM transmembrane pair domain protein
NECFGCCN_01604 2.3e-218 yqeG E transporter
NECFGCCN_01605 4e-156 ydbC 1.1.1.65 C oxidoreductase
NECFGCCN_01606 2.1e-126 ycgR M Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NECFGCCN_01607 2.3e-91 rcsV K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECFGCCN_01608 7.9e-126 yhjH 3.1.4.52 T Diguanylate phosphodiesterase
NECFGCCN_01609 1.4e-118 NU Fimbrial protein
NECFGCCN_01610 7.3e-178 NU Fimbrial protein
NECFGCCN_01611 0.0 htrE NU Outer membrane usher protein
NECFGCCN_01612 2.3e-125 focC M Pili and flagellar-assembly chaperone, PapD N-terminal domain
NECFGCCN_01613 4.2e-104 NU Fimbrial protein
NECFGCCN_01614 3.8e-28 S Protein of unknown function (DUF1471)
NECFGCCN_01615 5.6e-153 pecM EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_01616 6.5e-82 K transcriptional regulator
NECFGCCN_01617 5.8e-148 nicO U Belongs to the NiCoT transporter (TC 2.A.52) family
NECFGCCN_01618 2.1e-111 fimB K FimB is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimB switches fimA on
NECFGCCN_01619 1.6e-106 fimE K FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off
NECFGCCN_01620 8.9e-173 P (ABC) transporter
NECFGCCN_01621 1.2e-46 ydbM I acyl-CoA dehydrogenase
NECFGCCN_01622 6.9e-78 S reductase
NECFGCCN_01624 8.6e-287 ahpF O alkyl hydroperoxide reductase
NECFGCCN_01625 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
NECFGCCN_01626 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
NECFGCCN_01627 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NECFGCCN_01628 1.6e-82 S Putative small multi-drug export protein
NECFGCCN_01629 2e-74 ctsR K Belongs to the CtsR family
NECFGCCN_01630 0.0 clpC O Belongs to the ClpA ClpB family
NECFGCCN_01631 6.7e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NECFGCCN_01632 9.9e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NECFGCCN_01633 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NECFGCCN_01634 3.1e-122 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NECFGCCN_01635 1.1e-162 ybbR S Protein conserved in bacteria
NECFGCCN_01636 9.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NECFGCCN_01637 5.1e-27 gtrA S GtrA-like protein
NECFGCCN_01639 2e-88 ybhB S PFAM PEBP family protein
NECFGCCN_01640 6.9e-245 bioA 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NECFGCCN_01641 1.4e-195 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NECFGCCN_01642 2.7e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NECFGCCN_01643 6.1e-214 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NECFGCCN_01645 6.8e-67 intS L Belongs to the 'phage' integrase family
NECFGCCN_01648 4.2e-140 I radical SAM domain protein
NECFGCCN_01649 6.9e-50
NECFGCCN_01650 2e-165 T Nacht domain
NECFGCCN_01651 4.5e-192 T Restriction endonuclease
NECFGCCN_01653 0.0 pknK 2.7.11.1 K Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'
NECFGCCN_01654 4.8e-179 acoA C dehydrogenase e1 component
NECFGCCN_01655 3e-187 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NECFGCCN_01656 1.6e-253 acoC 2.3.1.12 C COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
NECFGCCN_01657 9e-251 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NECFGCCN_01658 1.7e-35 S Putative zinc ribbon domain
NECFGCCN_01659 4e-139 4.1.2.13 G Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA
NECFGCCN_01660 2.1e-94 glpP K Glycerol-3-phosphate responsive antiterminator
NECFGCCN_01661 1.7e-271 2.7.1.53 G Belongs to the FGGY kinase family
NECFGCCN_01662 9e-128 IQ reductase
NECFGCCN_01663 4.4e-167 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NECFGCCN_01664 1.9e-223 gatC G system Galactitol-specific IIC component
NECFGCCN_01665 1.6e-117 2.5.1.18 O Glutathione S-Transferase
NECFGCCN_01666 4e-136 M Methyltransferase domain
NECFGCCN_01667 1.6e-39 yjhX S Belongs to the UPF0386 family
NECFGCCN_01668 2.1e-185 csiD C May be involved in the control of utilization of gamma- aminobutyric acid
NECFGCCN_01669 1.4e-237 lhgO S L-2-hydroxyglutarate oxidase LhgO
NECFGCCN_01670 3.5e-274 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
NECFGCCN_01671 1e-240 gabT 2.6.1.19, 2.6.1.22, 2.6.1.48 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NECFGCCN_01672 3.9e-254 gabP E Gamma-aminobutyrate
NECFGCCN_01673 2.6e-118 csiR K Transcriptional
NECFGCCN_01674 1.6e-50
NECFGCCN_01675 2.8e-165 K Transcriptional regulator
NECFGCCN_01676 6.4e-190 pld1 1.1.1.122 C Aldo Keto reductase
NECFGCCN_01677 7.7e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_01678 1.6e-70 S Polyketide cyclase / dehydrase and lipid transport
NECFGCCN_01679 1.5e-23 S Protein of unknown function (DUF1471)
NECFGCCN_01680 8.7e-74 crl K Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32
NECFGCCN_01681 2.9e-248 frsA S Belongs to the UPF0255 family
NECFGCCN_01682 8.2e-84 gpt 2.4.2.22 F Acts on guanine, xanthine and to a lesser extent hypoxanthine
NECFGCCN_01683 6.3e-279 pepD E aminoacyl-histidine dipeptidase
NECFGCCN_01684 2e-74 yafP 5.3.1.16 K SOS response
NECFGCCN_01685 1.5e-197 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NECFGCCN_01686 7.5e-147 ugpQ_1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NECFGCCN_01688 5.7e-31 KT response to antibiotic
NECFGCCN_01689 1e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
NECFGCCN_01690 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
NECFGCCN_01691 8.8e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NECFGCCN_01692 1.8e-116 ylfI S tigr01906
NECFGCCN_01693 3.3e-135 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NECFGCCN_01695 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NECFGCCN_01696 1.6e-61 smtB K Transcriptional regulator
NECFGCCN_01697 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
NECFGCCN_01698 2.4e-75 P Mediates zinc uptake. May also transport other divalent cations
NECFGCCN_01699 1.2e-42 ydaL S protein conserved in bacteria
NECFGCCN_01700 5.6e-144 pcaR K transcriptional regulator
NECFGCCN_01701 2.7e-123 pcaI 2.8.3.6 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NECFGCCN_01702 3.4e-123 pcaJ 2.8.3.6 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NECFGCCN_01703 7.4e-84 pcaF 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
NECFGCCN_01704 2.5e-89 frdC 1.3.5.4 C NADH flavin oxidoreductase
NECFGCCN_01705 3.3e-127 frdC 1.3.5.4 C NADH flavin oxidoreductase
NECFGCCN_01706 1e-119 frdC 1.3.5.4 C NADH flavin
NECFGCCN_01707 2.8e-245 ttdT P transporter
NECFGCCN_01708 7.4e-283 E amino acid
NECFGCCN_01709 4.9e-97 S Protein of unknown function (DUF3156)
NECFGCCN_01710 4.9e-215 hdaH BQ COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
NECFGCCN_01713 1.3e-11 mliC S Membrane-bound lysozyme-inhibitor of c-type lysozyme
NECFGCCN_01714 2.8e-82 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NECFGCCN_01715 6.5e-230 dinF V Mate efflux family protein
NECFGCCN_01716 6.4e-54 S Psort location CytoplasmicMembrane, score
NECFGCCN_01717 3.1e-204 yeaN P transporter
NECFGCCN_01718 3.7e-73 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
NECFGCCN_01719 1.5e-141 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NECFGCCN_01720 5.9e-55
NECFGCCN_01721 8.7e-60
NECFGCCN_01722 1.1e-49
NECFGCCN_01723 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
NECFGCCN_01724 2e-217 EGP Transmembrane secretion effector
NECFGCCN_01725 4.3e-22
NECFGCCN_01726 5.1e-20 copA 3.6.3.54 P P-type ATPase
NECFGCCN_01727 9.2e-160 T Diguanylate cyclase
NECFGCCN_01728 1.3e-66 recC 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NECFGCCN_01729 0.0 ptrA 3.4.24.55, 3.4.24.56 O Belongs to the peptidase M16 family
NECFGCCN_01730 0.0 recB 3.1.11.5, 3.6.4.12 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA
NECFGCCN_01731 0.0 recD 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NECFGCCN_01733 3.3e-250 argA 2.3.1.1, 2.7.2.8 E Belongs to the acetyltransferase family. ArgA subfamily
NECFGCCN_01734 2.8e-227 amiC 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NECFGCCN_01735 8.9e-198 cobD 4.1.1.81 E decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin
NECFGCCN_01736 1.8e-159 pduX 2.7.1.177 Q GHMP kinase
NECFGCCN_01737 7.7e-222 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NECFGCCN_01738 2.3e-75 pduV E utilization protein
NECFGCCN_01739 3.8e-57 pduU E propanediol utilization protein
NECFGCCN_01740 2.2e-91 pduT CQ propanediol utilization protein
NECFGCCN_01741 2.3e-243 rnfC C NADH dehydrogenase
NECFGCCN_01742 3.6e-202 pduQ C alcohol dehydrogenase
NECFGCCN_01743 3.7e-244 pduP 1.2.1.87 C Aldehyde dehydrogenase
NECFGCCN_01744 1.2e-175 pduO 2.5.1.17 S adenosyltransferase
NECFGCCN_01745 8.2e-39 pduN CQ ethanolamine utilization protein
NECFGCCN_01746 9.7e-75 pduM S propanediol utilization protein
NECFGCCN_01747 1.3e-108 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NECFGCCN_01748 1.2e-60 pduK CQ BMC
NECFGCCN_01749 2.2e-39 pduJ CQ Carbon dioxide concentrating mechanism carboxysome shell protein
NECFGCCN_01750 1.5e-56 pduH S Dehydratase medium subunit
NECFGCCN_01751 0.0 pduG D dehydratase
NECFGCCN_01752 3e-90 pduE 4.2.1.28, 4.2.1.30 Q Dehydratase Small Subunit
NECFGCCN_01753 1.1e-119 pduD 4.2.1.28, 4.2.1.30 Q dehydratase, medium subunit
NECFGCCN_01754 0.0 pduC 4.2.1.28, 4.2.1.30 E Dehydratase large subunit
NECFGCCN_01755 5.2e-142 pduB E may be involved in the formation of the polyhedral organelles involved in propanediol degradation
NECFGCCN_01756 8.2e-42 pduA CQ Carbon dioxide concentrating mechanism carboxysome shell protein
NECFGCCN_01757 4.9e-148 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NECFGCCN_01758 7.2e-45 pocR K transcriptional regulator AraC family
NECFGCCN_01759 8e-114 pocR K transcriptional regulator AraC family
NECFGCCN_01760 6.6e-262 cbiA 6.3.5.11, 6.3.5.9 H Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source
NECFGCCN_01761 1.2e-182 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NECFGCCN_01762 1.7e-111 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
NECFGCCN_01763 9.7e-211 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NECFGCCN_01764 9.1e-107 cbiE 2.1.1.132, 2.1.1.289 H Catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a
NECFGCCN_01765 7.9e-97 cbiT 2.1.1.132, 2.1.1.196 H precorrin-6y C5,15-methyltransferase
NECFGCCN_01766 7e-144 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Precorrin-4 C(11)-methyltransferase
NECFGCCN_01767 4.4e-189 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin biosynthesis protein CbiG
NECFGCCN_01768 3.5e-129 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H precorrin-3B C17-methyltransferase
NECFGCCN_01769 3.2e-144 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H reductase
NECFGCCN_01770 1.7e-145 cbiK 4.99.1.3 H Catalyzes the insertion of Co(2 ) into sirohydrochlorin
NECFGCCN_01771 1.9e-127 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Belongs to the precorrin methyltransferase family
NECFGCCN_01772 6.4e-131 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NECFGCCN_01773 4.2e-22 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NECFGCCN_01774 1.1e-116 cbiQ P cobalt transport protein
NECFGCCN_01775 1.1e-150 cbiO 2.1.1.195 P Responsible for energy coupling to the transport system
NECFGCCN_01776 3.2e-286 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NECFGCCN_01777 8.5e-96 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
NECFGCCN_01778 6.3e-188 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NECFGCCN_01779 1.5e-164 pbpG 3.4.16.4 M Belongs to the peptidase S11 family
NECFGCCN_01780 1.9e-101 yohC S Membrane
NECFGCCN_01781 8e-89 yohD S Membrane
NECFGCCN_01782 7.1e-259 mdtQ MU RND efflux system, outer membrane lipoprotein
NECFGCCN_01783 4.3e-277 bglB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_01784 0.0 bglF 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Phosphotransferase System
NECFGCCN_01785 2.4e-150 bglG K antiterminator
NECFGCCN_01786 3.8e-270 oprB M COG3659 Carbohydrate-selective porin
NECFGCCN_01787 1.7e-176 dusC J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs
NECFGCCN_01788 2.4e-63 lrgA S UPF0299 membrane protein
NECFGCCN_01789 9.4e-108 yohK M effector of murein hydrolase
NECFGCCN_01790 1.7e-162 cdd 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NECFGCCN_01791 1.3e-131 sanA S Vancomycin high temperature exclusion protein
NECFGCCN_01792 4.5e-175 mglC G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_01793 5.9e-288 mglA 3.6.3.17 P import. Responsible for energy coupling to the transport system
NECFGCCN_01794 2e-183 mglB G Wtih MglAC is involved in the transport of beta-methylgalactoside
NECFGCCN_01795 8.8e-187 galS K transcriptional regulator
NECFGCCN_01796 3.5e-216 yeiB S Membrane
NECFGCCN_01797 9.1e-116 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase
NECFGCCN_01798 1.3e-159 yeiG 3.1.2.12 CE1 S Serine hydrolase involved in the detoxification of formaldehyde
NECFGCCN_01799 0.0 cirA P Receptor
NECFGCCN_01800 4.9e-160 ppaC 3.6.1.1 C inorganic pyrophosphatase
NECFGCCN_01801 9.9e-107 S Domain of unknown function (DUF1803)
NECFGCCN_01802 7.8e-102 ygaC J Belongs to the UPF0374 family
NECFGCCN_01803 5.9e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
NECFGCCN_01804 4.5e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NECFGCCN_01805 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
NECFGCCN_01806 1.7e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
NECFGCCN_01807 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_01808 6.6e-173 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NECFGCCN_01809 3.4e-166 bcrA V abc transporter atp-binding protein
NECFGCCN_01810 4.6e-216 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NECFGCCN_01811 3.6e-174 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NECFGCCN_01812 0.0 recJ L Single-stranded-DNA-specific exonuclease
NECFGCCN_01813 3.1e-130 dsbC 5.3.4.1 O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NECFGCCN_01814 3e-162 xerD D recombinase XerD
NECFGCCN_01815 3.5e-99 fldB C Low-potential electron donor to a number of redox enzymes
NECFGCCN_01816 2e-73 ygfX S Membrane
NECFGCCN_01817 1.5e-45 sdhE 1.3.5.1, 1.3.5.4 S An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NECFGCCN_01818 3.2e-178 ygfZ S Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication
NECFGCCN_01819 1.4e-113 yqfA S protein, hemolysin III
NECFGCCN_01820 2.4e-47 yqfB S Belongs to the UPF0267 family
NECFGCCN_01821 6.4e-131 ybbH_1 K transcriptional regulator
NECFGCCN_01822 2.8e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_01823 3.1e-54 scsA S resistance, protein
NECFGCCN_01824 1.3e-98 comFC K competence protein
NECFGCCN_01825 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NECFGCCN_01826 7.9e-140 yecS_2 E amino acid ABC transporter
NECFGCCN_01827 7.4e-138 glnH ET ABC transporter substrate-binding protein
NECFGCCN_01828 7.6e-158 K transcriptional regulator
NECFGCCN_01829 1.7e-176 P periplasmic binding protein
NECFGCCN_01830 8.5e-177 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_01831 1.9e-149 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_01832 6.9e-150 yusV 3.6.3.34 HP (ABC) transporter
NECFGCCN_01833 0.0 fecA P Receptor
NECFGCCN_01834 1.3e-248 S LVIVD repeat
NECFGCCN_01835 6.3e-196 G Sugar ABC Transporter
NECFGCCN_01836 4e-168 rbsC_3 G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_01837 1.5e-280 mglA_3 3.6.3.17 G (ABC) transporter
NECFGCCN_01838 5.7e-200 gldA 1.1.1.1, 1.1.1.6 C Iron-containing alcohol dehydrogenase
NECFGCCN_01839 1.1e-125 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_01840 3.3e-49 relE DJ nuclease activity
NECFGCCN_01841 1.5e-68 K transcriptional regulator
NECFGCCN_01842 2.4e-32 ybdD S Pfam:DUF466
NECFGCCN_01843 2.9e-185 cstA T Carbon starvation protein
NECFGCCN_01844 4.5e-291 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NECFGCCN_01845 2.2e-73 rplI J binds to the 23S rRNA
NECFGCCN_01846 6.5e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NECFGCCN_01847 1.8e-47 veg S Biofilm formation stimulator VEG
NECFGCCN_01848 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NECFGCCN_01849 1.1e-10
NECFGCCN_01850 7.7e-53 ypaA M Membrane
NECFGCCN_01851 2.3e-93 XK27_06935 K transcriptional regulator
NECFGCCN_01852 5.4e-26 S Protein of unknown function (DUF4089)
NECFGCCN_01853 1.6e-299 ywrD 2.3.2.2, 3.4.19.13 M Gamma-glutamyltransferase
NECFGCCN_01854 1.6e-149 K transcriptional regulator
NECFGCCN_01855 6.2e-140 IV02_26540 ET belongs to the bacterial solute-binding protein 3 family
NECFGCCN_01856 1.2e-115 P amino acid ABC transporter
NECFGCCN_01857 6.4e-114 yecS_3 P amino acid ABC transporter
NECFGCCN_01858 9.9e-132 glnQ_2 3.6.3.21 E amino acid ABC transporter, ATP-binding protein
NECFGCCN_01859 1.1e-242 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NECFGCCN_01860 1.3e-21 motX S Sel1-like repeats.
NECFGCCN_01861 6.7e-215 araT 2.6.1.1 E Aminotransferase
NECFGCCN_01862 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NECFGCCN_01863 1.9e-84 usp 3.5.1.28 CBM50 S CHAP domain
NECFGCCN_01864 1e-82 mreD M rod shape-determining protein MreD
NECFGCCN_01865 2e-58 mreC M Involved in formation and maintenance of cell shape
NECFGCCN_01866 1.8e-128 L Belongs to the 'phage' integrase family
NECFGCCN_01868 3e-180 iroB CG Protein of unknown function (DUF1205)
NECFGCCN_01870 4.8e-131 iroD P enterochelin esterase
NECFGCCN_01875 4e-176 mchC S Uncharacterized ACR, YdiU/UPF0061 family
NECFGCCN_01876 6e-77 mchD S RTX toxin acyltransferase family
NECFGCCN_01877 2.8e-198 mclA M Secretion Protein
NECFGCCN_01878 0.0 mchF V COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NECFGCCN_01880 1.3e-64 CP_0355 S CAAX protease self-immunity
NECFGCCN_01881 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NECFGCCN_01882 5.5e-137 divIVA D Cell division initiation protein
NECFGCCN_01883 1.1e-136 ylmH S conserved protein, contains S4-like domain
NECFGCCN_01884 9.1e-83 sepF D cell septum assembly
NECFGCCN_01885 8.1e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NECFGCCN_01886 6.2e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NECFGCCN_01887 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NECFGCCN_01888 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NECFGCCN_01889 3.1e-198 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NECFGCCN_01890 9e-248 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NECFGCCN_01891 9.8e-43 hipB K Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the toxic effect of cognate toxin HipA. Also neutralizes the toxic effect of non- cognate toxin YjjJ. Binds to operator sites with the consensus sequence 5-'TATCCN(8)GGATA-3' to repress the hipBA operon promoter
NECFGCCN_01892 2.8e-246 hipA 2.7.11.1 S protein related to capsule biosynthesis enzymes
NECFGCCN_01893 1.1e-250 yddW S Lipoprotein
NECFGCCN_01894 2.1e-180 NU Fimbrial protein
NECFGCCN_01895 0.0 NU Usher protein
NECFGCCN_01896 5e-125 NU pilus organization
NECFGCCN_01897 1e-91 phfS NU cell adhesion
NECFGCCN_01899 4e-147 map 3.4.11.18 E Methionine aminopeptidase
NECFGCCN_01900 2.7e-32 S ParD-like antitoxin of type II bacterial toxin-antitoxin system
NECFGCCN_01901 8.2e-38
NECFGCCN_01902 0.0 T Diguanylate cyclase
NECFGCCN_01903 1.9e-148 besA S hydrolase of the alpha beta superfamily
NECFGCCN_01905 9.1e-34
NECFGCCN_01906 7.9e-76 fruB_2 G phosphotransferase system, IIa
NECFGCCN_01907 9.3e-259 iolT EGP Major facilitator Superfamily
NECFGCCN_01908 4.7e-257 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G 6-phospho-alpha-glucosidase
NECFGCCN_01909 7.3e-270 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system
NECFGCCN_01910 1.2e-123 K UTRA
NECFGCCN_01911 1.6e-113 S membrane transporter protein
NECFGCCN_01912 1.6e-27 MA20_06395 K transcriptional regulator
NECFGCCN_01913 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
NECFGCCN_01914 0.0 copA 3.6.3.54 P P-type ATPase
NECFGCCN_01915 1.6e-73 copY K negative regulation of transcription, DNA-templated
NECFGCCN_01917 4.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
NECFGCCN_01918 2.6e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
NECFGCCN_01919 7.9e-129 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NECFGCCN_01920 1.7e-57 S there are four paralogs in L.lactis
NECFGCCN_01921 2.5e-148 gsiD P transport
NECFGCCN_01922 1.9e-164 gsiC P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECFGCCN_01923 1.6e-296 gsiB E Extracellular solute-binding protein, family 5
NECFGCCN_01924 0.0 gsiA P ATPase activity
NECFGCCN_01925 1.6e-171 iaaA 3.4.19.5, 3.5.1.1 E asparaginase
NECFGCCN_01926 6.4e-232 moeA 2.10.1.1 H molybdopterin
NECFGCCN_01927 7.5e-135 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NECFGCCN_01928 1.5e-169 ybiY 1.97.1.4 O Pyruvate formate lyase-activating protein
NECFGCCN_01929 0.0 ybiW 2.3.1.54 C Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde
NECFGCCN_01930 5.4e-147 supH 3.1.3.102, 3.1.3.104, 3.1.3.23 C Hydrolase
NECFGCCN_01931 6.5e-248 ybiU S Protein of unknown function (DUF1479)
NECFGCCN_01932 1.8e-197 cytR_1 K Periplasmic binding protein LacI transcriptional regulator
NECFGCCN_01933 6.2e-246 exuT_1 G Major facilitator superfamily
NECFGCCN_01934 0.0 yicI 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NECFGCCN_01935 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NECFGCCN_01936 1e-105 3.1.3.18 S IA, variant 1
NECFGCCN_01937 1.9e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NECFGCCN_01938 5.9e-56 lrgA S Effector of murein hydrolase LrgA
NECFGCCN_01940 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
NECFGCCN_01941 1.7e-71 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NECFGCCN_01942 4.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NECFGCCN_01943 3.1e-101 wecD M Acetyltransferase (GNAT) domain
NECFGCCN_01944 5.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NECFGCCN_01945 3e-63 GK ROK family
NECFGCCN_01946 4.6e-29 Z012_07620 2.7.1.180 S protein conserved in bacteria
NECFGCCN_01947 1.6e-235 nqrF 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
NECFGCCN_01948 7.3e-101 nqrE 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NECFGCCN_01949 1.7e-108 nqrD 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NECFGCCN_01950 2.2e-140 nqrC 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NECFGCCN_01951 1.1e-234 nqrB 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NECFGCCN_01952 1.9e-250 nqrA 1.6.5.8 C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NECFGCCN_01953 2e-140 yafK S ErfK YbiS YcfS YnhG family protein
NECFGCCN_01954 1.6e-153 yafJ S glutamine amidotransferase
NECFGCCN_01955 4.5e-103 gmhA 5.3.1.28 G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
NECFGCCN_01956 0.0 fadE I acyl-CoA dehydrogenase
NECFGCCN_01957 3.7e-145 yafV 3.5.1.3 S Hydrolase
NECFGCCN_01958 5e-94 eamB E LysE type translocator
NECFGCCN_01959 6.3e-157 yfiE K Transcriptional regulator
NECFGCCN_01961 4.2e-30
NECFGCCN_01963 1.7e-22 S dextransucrase activity
NECFGCCN_01964 5.5e-10 S dextransucrase activity
NECFGCCN_01965 4.1e-68 pcaC 1.1.1.31, 3.1.1.24, 4.1.1.44 S 4-carboxymuconolactone decarboxylase
NECFGCCN_01966 3.3e-138 pcaD 3.1.1.24, 3.4.11.5, 4.1.1.44 S 3-oxoadipate enol-lactonase
NECFGCCN_01967 7.5e-211 pcaB 5.5.1.2 F 3-carboxy-cis,cis-muconate cycloisomerase
NECFGCCN_01968 8.5e-87 lrp K Transcriptional regulator
NECFGCCN_01969 1.7e-182 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NECFGCCN_01970 0.0 cydD V (ABC) transporter
NECFGCCN_01971 5.4e-298 cydC V (ABC) transporter
NECFGCCN_01972 2.9e-133 aat 2.3.2.6 O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NECFGCCN_01973 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NECFGCCN_01974 0.0 clpA O Belongs to the ClpA ClpB family
NECFGCCN_01975 8e-54 clpS S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NECFGCCN_01976 8.1e-37 cspD K Cold shock
NECFGCCN_01977 0.0 macB V Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides
NECFGCCN_01978 3e-93 macA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_01979 7.8e-59 macA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_01980 0.0 ybjD L ATP-dependent endonuclease of the OLD family
NECFGCCN_01981 1e-122 aqpZ G Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity
NECFGCCN_01982 4.2e-148 ybjE S membrane
NECFGCCN_01983 0.0 hcp 1.7.99.1 C Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
NECFGCCN_01984 2.8e-182 hcr C oxidoreductase
NECFGCCN_01985 1.7e-27 mmuP E amino acid
NECFGCCN_01986 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NECFGCCN_01987 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NECFGCCN_01988 9.7e-22
NECFGCCN_01989 2.9e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NECFGCCN_01990 2.7e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NECFGCCN_01991 5.8e-211 mvaS 2.3.3.10 I synthase
NECFGCCN_01992 1.6e-70 paaG 5.3.3.18 I Enoyl-CoA hydratase/isomerase
NECFGCCN_01993 8e-255 paaH 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 C 3-hydroxyacyl-CoA dehydrogenase
NECFGCCN_01994 1e-72 paaI Q Phenylacetic acid degradation protein PaaD
NECFGCCN_01995 1.5e-217 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
NECFGCCN_01996 3.9e-256 paaK 6.2.1.30 H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NECFGCCN_01997 2.1e-174 paaX K phenylacetic acid degradation operon negative regulatory protein
NECFGCCN_01998 8.2e-84 paaY S Phenylacetic acid degradation protein PaaY
NECFGCCN_01999 1.8e-74 S Glutathione-dependent formaldehyde-activating
NECFGCCN_02000 2e-106 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NECFGCCN_02001 0.0 hrpA 3.6.4.13 L ATP-dependent helicase hrpA
NECFGCCN_02002 1.7e-125 mdmC 2.1.1.104 H Methyltransferase domain
NECFGCCN_02003 1.7e-185 oprM M membrane
NECFGCCN_02004 2.9e-140 hlyD V Secretion protein
NECFGCCN_02005 6.5e-134 EGP Major facilitator Superfamily
NECFGCCN_02006 7.5e-22 K helix_turn_helix gluconate operon transcriptional repressor
NECFGCCN_02007 1.7e-89 U ABC-2 type transporter
NECFGCCN_02008 7.4e-92 V AAA domain, putative AbiEii toxin, Type IV TA system
NECFGCCN_02009 3.4e-97 ulaD 4.1.1.85, 4.1.2.43 G Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization
NECFGCCN_02010 6.6e-81 ulaC 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphotransferase System
NECFGCCN_02011 4e-50 ulaB 2.7.1.194, 2.7.1.200 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport
NECFGCCN_02012 4.2e-256 ulaA 2.7.1.194 G pts system
NECFGCCN_02013 2e-218 ulaG S Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions
NECFGCCN_02014 3.4e-135 ulaR K transcriptional regulator
NECFGCCN_02015 6.1e-134 yjfP S esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro
NECFGCCN_02016 3.1e-50 bsmA S In Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility
NECFGCCN_02017 4.4e-40 yjfN S Protein of unknown function (DUF1471)
NECFGCCN_02018 0.0 aidB I acyl-CoA dehydrogenase
NECFGCCN_02019 1.4e-130 rlmB 2.1.1.185, 2.1.1.34 J Specifically methylates the ribose of guanosine 2251 in 23S rRNA
NECFGCCN_02020 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NECFGCCN_02021 3.9e-72 nsrR K Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity
NECFGCCN_02022 4.2e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NECFGCCN_02023 3.5e-28 yjeT S protein conserved in bacteria
NECFGCCN_02024 3.1e-28
NECFGCCN_02025 7.3e-92 ameR K transcriptional regulator
NECFGCCN_02026 1e-179 GM COG0451 Nucleoside-diphosphate-sugar epimerases
NECFGCCN_02027 7.6e-158 K transcriptional regulator
NECFGCCN_02028 4.9e-182 P ABC transporter substrate-binding protein
NECFGCCN_02029 8.1e-156 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_02031 3.3e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NECFGCCN_02032 3.8e-199 G COG0457 FOG TPR repeat
NECFGCCN_02033 1.9e-124 V abc transporter atp-binding protein
NECFGCCN_02035 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NECFGCCN_02036 1.8e-47 celC 2.7.1.196, 2.7.1.205 G PTS system, cellobiose-specific IIA component
NECFGCCN_02037 1.7e-246 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_02038 7.4e-52 celA 2.7.1.196, 2.7.1.205 G Phosphotransferase system, lactose cellobiose-specific IIB subunit
NECFGCCN_02039 6.2e-171 ascG_1 K transcriptional regulator
NECFGCCN_02040 1.1e-253 EGP Major facilitator Superfamily
NECFGCCN_02041 2e-249 ligB 1.13.11.57, 1.13.11.8 S Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols
NECFGCCN_02042 1e-226 K transcriptional regulator
NECFGCCN_02043 3.4e-140 MA20_26640 4.2.1.83 S PFAM LmbE family protein
NECFGCCN_02044 1.2e-129 ligK 4.1.3.17 H methyltransferase
NECFGCCN_02045 6.4e-204 fldA 5.3.2.8 P protein conserved in bacteria
NECFGCCN_02046 9.5e-150 fldX 1.1.1.31 I 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NECFGCCN_02047 8.1e-45
NECFGCCN_02048 1.6e-155 yicL EG transporter
NECFGCCN_02049 1.2e-08 L Integrase core domain
NECFGCCN_02050 6.1e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NECFGCCN_02051 4.6e-175 acoB C dehydrogenase E1 component
NECFGCCN_02052 9e-166 acoA C Acetoin dehydrogenase E1 component subunit alpha
NECFGCCN_02053 4.3e-173 pdhD 1.8.1.4 C Dehydrogenase
NECFGCCN_02056 1.4e-11 K Helix-turn-helix XRE-family like proteins
NECFGCCN_02057 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NECFGCCN_02058 1.7e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NECFGCCN_02059 3.4e-100 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NECFGCCN_02060 4.7e-100 phrB 4.1.99.3 L Belongs to the DNA photolyase family
NECFGCCN_02061 2.1e-49 dtpD U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_02062 4.2e-98 ynjA S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NECFGCCN_02063 1.1e-122 ydjZ S TVP38 TMEM64 family inner membrane protein ydjZ
NECFGCCN_02064 4e-108 ydjX P SNARE associated Golgi protein
NECFGCCN_02065 1.2e-159 xthA 3.1.11.2 L Exodeoxyribonuclease III
NECFGCCN_02066 7.9e-235 argD 2.6.1.11, 2.6.1.17, 2.6.1.81 E aminotransferase
NECFGCCN_02067 8.3e-201 astA 1.2.1.71, 2.3.1.109 E arginine N-succinyltransferase
NECFGCCN_02068 1.3e-279 astD 1.2.1.71 C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate
NECFGCCN_02069 2.4e-245 astB 3.5.3.23 E Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)
NECFGCCN_02070 4.4e-188 astE 3.5.1.96 E Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily
NECFGCCN_02071 6.8e-81 spy NPTU P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein
NECFGCCN_02072 4e-164 cho 2.7.7.7 L Nuclease subunit of the excinuclease complex
NECFGCCN_02073 7.9e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NECFGCCN_02074 1.8e-56 osmE J activator of ntr-like gene protein
NECFGCCN_02075 3.2e-50 chbB 2.7.1.196, 2.7.1.205 G protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar
NECFGCCN_02076 4.7e-236 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_02077 5.7e-53 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase System
NECFGCCN_02078 5.1e-153 chbR K transcriptional regulator
NECFGCCN_02079 3.9e-259 chbF 3.2.1.86 GT4 G Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate
NECFGCCN_02080 7.8e-132 chbG 2.7.1.196, 2.7.1.205, 3.5.1.105 G Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF
NECFGCCN_02081 0.0 katE 1.11.1.6 C serves to protect cells from the toxic effects of hydrogen peroxide
NECFGCCN_02082 6.2e-41 cedA D Cell division activator CedA
NECFGCCN_02083 1e-230 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NECFGCCN_02084 2.4e-112 ydjM S membrane-bound metal-dependent
NECFGCCN_02085 2.7e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_02086 5.3e-116 yniC 3.1.3.23 S HAD-superfamily hydrolase subfamily IA, variant 3
NECFGCCN_02087 8.1e-91 yniB S Membrane
NECFGCCN_02088 1.9e-68 yciA I acyl-CoA thioester hydrolase
NECFGCCN_02089 0.0 P Receptor
NECFGCCN_02090 2.2e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NECFGCCN_02091 1.6e-183 mtnA 4.2.1.109, 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NECFGCCN_02092 1.8e-242 appA 3.1.3.10, 3.1.3.2, 3.1.3.26 S Acid phosphatase
NECFGCCN_02093 2.2e-249 uhpC_2 G transporter
NECFGCCN_02094 6e-154 3.1.3.25 G inositol monophosphatase
NECFGCCN_02095 1.6e-188 K transcriptional regulator
NECFGCCN_02096 2.3e-237 codA 3.5.4.1, 3.5.4.21 F cytosine deaminase
NECFGCCN_02097 4.6e-230 QT transcriptional regulator
NECFGCCN_02100 3.8e-177 wbbI M transferase activity, transferring glycosyl groups
NECFGCCN_02101 1e-184 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
NECFGCCN_02102 2.2e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
NECFGCCN_02103 2.2e-244 epsU S Polysaccharide biosynthesis protein
NECFGCCN_02104 1.5e-126 cps3F
NECFGCCN_02105 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NECFGCCN_02106 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NECFGCCN_02107 3.3e-129 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NECFGCCN_02108 5e-63 WQ51_03320 S cog cog4835
NECFGCCN_02109 2.8e-146 XK27_08360 S EDD domain protein, DegV family
NECFGCCN_02110 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NECFGCCN_02111 1.1e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NECFGCCN_02112 0.0 yfmR S abc transporter atp-binding protein
NECFGCCN_02113 1.7e-26 U response to pH
NECFGCCN_02114 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NECFGCCN_02115 1e-209 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NECFGCCN_02116 9e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NECFGCCN_02118 6.6e-161 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NECFGCCN_02119 2.2e-38 ybaB L Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NECFGCCN_02120 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NECFGCCN_02121 0.0 htpG O Molecular chaperone. Has ATPase activity
NECFGCCN_02122 1.1e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NECFGCCN_02123 2.8e-182 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NECFGCCN_02124 1.5e-255 gsk 2.7.1.20, 2.7.1.73, 2.7.1.92 G COG0524 Sugar kinases, ribokinase family
NECFGCCN_02125 2.9e-296 ybaL P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NECFGCCN_02126 3.7e-216 fsr P fosmidomycin resistance protein
NECFGCCN_02127 0.0 ushA 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NECFGCCN_02128 4.7e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NECFGCCN_02129 4.3e-149 ybaP S protein conserved in bacteria
NECFGCCN_02130 0.0 copA 3.6.3.54 P P-type atpase
NECFGCCN_02131 3.8e-72 cueR K Transcriptional regulator
NECFGCCN_02132 5.7e-77 ybbJ OU Membrane protein implicated in regulation of membrane protease activity
NECFGCCN_02133 6.8e-122 qmcA O COG0330 Membrane protease subunits stomatin prohibitin homologs
NECFGCCN_02134 1.4e-119 ybbL S abc transporter atp-binding protein
NECFGCCN_02135 6.8e-131 ybbM S transport system permease component
NECFGCCN_02136 6.1e-149 ybbN O Thioredoxin
NECFGCCN_02137 8.8e-139 ybbO S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_02138 2.1e-115 tesA 3.1.1.5 E COG2755 Lysophospholipase L1 and related esterases
NECFGCCN_02139 0.0 ybbP Q ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component
NECFGCCN_02140 1.8e-225 omp M Membrane
NECFGCCN_02141 3.1e-220 rgpAc GT4 M group 1 family protein
NECFGCCN_02142 4.8e-76 S Domain of Unknown Function with PDB structure (DUF3862)
NECFGCCN_02143 5.4e-92 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_02144 6.7e-251 yeeF E Amino Acid
NECFGCCN_02145 2.6e-134 yeeY K transcriptional regulator
NECFGCCN_02146 9e-158 yeeZ GM COG0451 Nucleoside-diphosphate-sugar epimerases
NECFGCCN_02147 7e-164 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NECFGCCN_02148 6.3e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NECFGCCN_02149 1e-193 hisC 1.1.1.23, 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NECFGCCN_02150 1.7e-209 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19 E Histidine biosynthesis bifunctional protein HisB
NECFGCCN_02151 1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NECFGCCN_02152 7.4e-135 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NECFGCCN_02153 2.4e-144 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NECFGCCN_02154 8.1e-108 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NECFGCCN_02155 1.4e-136 M Glycosyltransferases involved in cell wall biogenesis
NECFGCCN_02156 1.8e-185 wbbO 2.4.1.52 GT4 M glycosyl transferase group 1
NECFGCCN_02157 1.3e-112 cps3B S Glycosyl Transferase
NECFGCCN_02158 9.3e-201 glf 5.4.99.9 M UDP-galactopyranose mutase
NECFGCCN_02159 3.9e-305 wbbM M Glycosyl Transferase
NECFGCCN_02160 1.6e-129 rfbB 3.6.3.38, 3.6.3.40 GM ABC-type polysaccharide polyol phosphate transport system ATPase component
NECFGCCN_02161 3.9e-131 rfbA GM Transport permease protein
NECFGCCN_02162 1.3e-190 capI 5.1.3.6 M epimerase dehydratase
NECFGCCN_02163 1.4e-217 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NECFGCCN_02164 2.3e-246 manB 5.4.2.2, 5.4.2.8 G phosphomannomutase
NECFGCCN_02165 1e-254 cpsB 2.7.7.13, 5.3.1.8 GM Belongs to the mannose-6-phosphate isomerase type 2 family
NECFGCCN_02166 1e-262 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NECFGCCN_02167 9.2e-179 wcaJ M Bacterial sugar transferase
NECFGCCN_02168 2.6e-22 2.3.1.157, 2.3.1.79, 2.7.7.23 S Bacterial transferase hexapeptide (six repeats)
NECFGCCN_02169 7.3e-08 S outer membrane
NECFGCCN_02170 2.3e-111 wzxC S biosynthesis protein
NECFGCCN_02171 1e-46
NECFGCCN_02172 3e-82 M transferase activity, transferring glycosyl groups
NECFGCCN_02173 2.5e-86 G glycosyl transferase group 1
NECFGCCN_02174 1.2e-72 cps4F 2.4.1.306 GT4 M Glycosyl transferase 4-like domain
NECFGCCN_02175 1e-285 wzc D protein involved in exopolysaccharide biosynthesis
NECFGCCN_02176 2e-11 etp 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NECFGCCN_02177 1.2e-208 V SLBB domain
NECFGCCN_02178 5.1e-265 S Capsule assembly protein Wzi
NECFGCCN_02179 1e-105 I COG0671 Membrane-associated phospholipid phosphatase
NECFGCCN_02180 4.6e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NECFGCCN_02181 8.8e-282 yegH P membrane protein, terc
NECFGCCN_02182 0.0 asmA M Protein involved in outer membrane biogenesis
NECFGCCN_02183 1e-107 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
NECFGCCN_02184 3.9e-116 udk 2.7.1.48 F Cytidine monophosphokinase
NECFGCCN_02185 9e-153 alkA 3.2.2.21 L 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NECFGCCN_02186 3.9e-251 yegD O Belongs to the heat shock protein 70 family
NECFGCCN_02187 0.0 T PhoQ Sensor
NECFGCCN_02188 2.9e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_02189 2.1e-14
NECFGCCN_02190 4.7e-103 K response regulator
NECFGCCN_02191 2.9e-219 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NECFGCCN_02192 3.6e-203 mdtA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_02193 9.8e-26 mdtB V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_02194 5.8e-46 mdtB V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_02195 3.6e-28
NECFGCCN_02197 9e-81
NECFGCCN_02198 1.8e-58 S protein conserved in bacteria
NECFGCCN_02199 7.7e-77 K Acetyltransferase (GNAT) family
NECFGCCN_02200 5.2e-41 S Protein of unknown function (DUF1778)
NECFGCCN_02201 3.8e-56
NECFGCCN_02202 6.9e-184 1.6.5.5 C Zinc-binding dehydrogenase
NECFGCCN_02203 1.8e-188 lacI K Periplasmic binding protein LacI transcriptional regulator
NECFGCCN_02204 0.0 lacZ 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NECFGCCN_02205 4.8e-219 lacY P LacY proton/sugar symporter
NECFGCCN_02206 5.3e-43 L cog cog1662
NECFGCCN_02207 5.3e-46 L PFAM Insertion element protein
NECFGCCN_02208 2.6e-32 S Protein of unknown function (DUF2534)
NECFGCCN_02209 6.9e-307 oprC P Receptor
NECFGCCN_02210 2.5e-89 pat 2.3.1.183 M acetyltransferase
NECFGCCN_02211 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NECFGCCN_02212 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NECFGCCN_02213 1e-125 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NECFGCCN_02214 2.1e-120 sdaAB 4.3.1.17 E L-serine dehydratase
NECFGCCN_02215 7.6e-147 sdaAA 4.3.1.17 E L-serine dehydratase
NECFGCCN_02216 5.3e-90 XK27_08140 K Bacterial regulatory proteins, tetR family
NECFGCCN_02217 2.3e-99 ypgQ F HD superfamily hydrolase
NECFGCCN_02218 7.5e-128 S CAAX amino terminal protease family
NECFGCCN_02219 3.2e-110 cutC P Participates in the control of copper homeostasis
NECFGCCN_02221 4.1e-21 S Domain of unknown function (DUF4767)
NECFGCCN_02222 1.9e-21 S Domain of unknown function (DUF4300)
NECFGCCN_02223 2.2e-108 yvyE 3.4.13.9 S YigZ family
NECFGCCN_02224 7e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NECFGCCN_02225 2.5e-110 acuB S CBS domain
NECFGCCN_02226 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NECFGCCN_02227 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NECFGCCN_02228 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_02229 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_02230 8.5e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NECFGCCN_02231 1.9e-46 ylbG S UPF0298 protein
NECFGCCN_02232 2.4e-72 ylbF S Belongs to the UPF0342 family
NECFGCCN_02233 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NECFGCCN_02234 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NECFGCCN_02235 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
NECFGCCN_02236 2.9e-262 XK27_07020 S Belongs to the UPF0371 family
NECFGCCN_02238 4.7e-130 dtpA U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_02240 1.2e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NECFGCCN_02241 1.6e-118 rnfE 2.3.1.243, 4.2.99.18 C Part of a membrane complex involved in electron transport
NECFGCCN_02242 4.6e-114 rnfG C Part of a membrane complex involved in electron transport
NECFGCCN_02243 1.1e-192 rnfD 1.6.5.8 C Part of a membrane complex involved in electron transport
NECFGCCN_02244 8.7e-41 L InsA N-terminal domain
NECFGCCN_02245 7.3e-78 Q Escherichia coli O157 H7 ortholog z1925
NECFGCCN_02246 2.3e-12 K luxR family
NECFGCCN_02248 1.2e-107 pagO EG EamA-like transporter family
NECFGCCN_02250 0.0 iroN P This protein is involved in the initial step of iron uptake by binding ferrienterobactin (Fe-ENT), an iron chelatin siderophore that allows E.coli to extract iron from the environment. FepA also acts as a receptor for colicins B and D
NECFGCCN_02251 1.7e-197 iroD P Domain of unknown function (DUF3327)
NECFGCCN_02252 0.0 iroC V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
NECFGCCN_02253 1.1e-198 iroB CG Protein of unknown function (DUF1205)
NECFGCCN_02254 3.6e-109 ibrB K ParB-like nuclease domain
NECFGCCN_02255 2.2e-240 ibrA S Domain of unknown function (DUF3440)
NECFGCCN_02256 3.8e-20 L PFAM transposase IS66
NECFGCCN_02257 1.8e-17 hokB S Hok/gef family
NECFGCCN_02261 1.5e-118 S PAAR repeat-containing protein
NECFGCCN_02263 1.6e-12 L Transposase
NECFGCCN_02264 6.9e-192 mcrB L restriction endonuclease
NECFGCCN_02265 7.8e-47 ykfI S Toxic component of a toxin-antitoxin (TA) system. Overexpression results in inhibition of growth in liquid cultures and a decrease in colony formation
NECFGCCN_02266 2e-55 yeeU S CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A
NECFGCCN_02267 2.5e-92 radC L RadC-like JAB domain
NECFGCCN_02268 4.1e-80 S Antirestriction protein
NECFGCCN_02269 7.4e-152 S Domain of unknown function (DUF932)
NECFGCCN_02270 1.8e-70 ykfB
NECFGCCN_02271 9.2e-24
NECFGCCN_02273 8.2e-131 yfjR K WYL domain
NECFGCCN_02274 1.3e-151 S GTP-binding protein
NECFGCCN_02275 4.7e-15 pdl 3.1.1.3 I Lipase (class 3)
NECFGCCN_02276 6.7e-162
NECFGCCN_02277 3.7e-105 S Inovirus Gp2
NECFGCCN_02278 1.5e-29 K Prophage CP4-57 regulatory protein (AlpA)
NECFGCCN_02279 4.3e-112
NECFGCCN_02280 8.3e-37 S Inovirus Gp2
NECFGCCN_02281 0.0 L DEAD-like helicases superfamily
NECFGCCN_02282 9e-310
NECFGCCN_02283 4e-219
NECFGCCN_02284 0.0 L DNA helicase
NECFGCCN_02285 0.0 L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NECFGCCN_02286 0.0 V Type II restriction enzyme, methylase subunits
NECFGCCN_02287 0.0 hepA K Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NECFGCCN_02288 0.0 L Helicase conserved C-terminal domain
NECFGCCN_02289 0.0
NECFGCCN_02290 1.4e-21
NECFGCCN_02291 2.7e-262 U nuclear chromosome segregation
NECFGCCN_02292 4.6e-118 M OmpA family
NECFGCCN_02293 5.9e-189 V HNH nucleases
NECFGCCN_02294 9.5e-231 intB L Belongs to the 'phage' integrase family
NECFGCCN_02296 1.8e-119 ybcF 4.2.1.1 P Reversible hydration of carbon dioxide
NECFGCCN_02297 9.8e-256 ychM 4.2.1.1 P transporter
NECFGCCN_02298 3.3e-194 yjgB 1.1.1.1 S alcohol dehydrogenase
NECFGCCN_02299 1.2e-157 MA20_28410 P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_02300 8.4e-20 MA20_28405 P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_02301 1.2e-126 MA20_28405 P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_02302 2.6e-165 cpdA 2.1.2.2, 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NECFGCCN_02303 1.1e-195 3.6.3.20 P Belongs to the ABC transporter superfamily
NECFGCCN_02304 2.2e-246 MA20_28400 G Extracellular solute-binding protein
NECFGCCN_02305 1.7e-178 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NECFGCCN_02306 5.3e-172 iolH G Sugar phosphate isomerases epimerases
NECFGCCN_02307 9e-192 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)
NECFGCCN_02308 0.0 iolD 3.7.1.22 E Belongs to the TPP enzyme family
NECFGCCN_02309 0.0 iolC 2.7.1.92 G 5-dehydro-2-deoxygluconokinase
NECFGCCN_02310 4.7e-149 Z012_10240 K transcriptional regulator
NECFGCCN_02311 9.6e-128 adcB P ABC transporter (Permease
NECFGCCN_02312 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
NECFGCCN_02313 5e-70 adcR K transcriptional
NECFGCCN_02314 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NECFGCCN_02315 3.6e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NECFGCCN_02316 2.7e-26
NECFGCCN_02317 4.1e-189 sufB O assembly protein SufB
NECFGCCN_02318 3.2e-53 gstR K transcriptional regulator
NECFGCCN_02319 1.1e-273 bmr3 EGP Major facilitator Superfamily
NECFGCCN_02320 1.3e-114 K Transcriptional regulator
NECFGCCN_02321 3.2e-71 K histone acetyltransferase HPA2 and related acetyltransferases
NECFGCCN_02322 1.6e-197 mexA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_02323 0.0 mexB V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_02324 4.1e-240 ibeB M RND efflux system, outer membrane lipoprotein
NECFGCCN_02325 2.8e-197 tcaB EGP Major facilitator Superfamily
NECFGCCN_02326 4.6e-131 murQ 4.2.1.126 H Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NECFGCCN_02327 2e-111 murP 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is
NECFGCCN_02328 5.9e-55 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NECFGCCN_02329 1.1e-25 amt P Ammonium Transporter
NECFGCCN_02330 1e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
NECFGCCN_02331 2.6e-95 S HD domain
NECFGCCN_02332 1e-143 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NECFGCCN_02333 4e-61 S Bacterial inner membrane protein
NECFGCCN_02335 1.1e-107 3.4.17.14, 3.5.1.28 NU amidase activity
NECFGCCN_02336 3.5e-294 nptA P COG1283 Na phosphate symporter
NECFGCCN_02337 2.2e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NECFGCCN_02338 7.7e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
NECFGCCN_02339 1.6e-110 cps4C M biosynthesis protein
NECFGCCN_02340 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NECFGCCN_02341 1.2e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NECFGCCN_02342 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NECFGCCN_02343 6.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
NECFGCCN_02344 4.9e-81 copY K Copper transport repressor, CopY TcrY family
NECFGCCN_02345 0.0 3.6.3.4 P P-type ATPase
NECFGCCN_02347 1.2e-101 cadD P cadmium resistance
NECFGCCN_02348 4.5e-55 cadX K transcriptional regulator, ArsR family
NECFGCCN_02349 1.7e-42 yiiE S protein homotetramerization
NECFGCCN_02350 1.2e-18
NECFGCCN_02351 1.5e-29 K Helix-turn-helix domain
NECFGCCN_02353 2e-149 srtB 3.4.22.70 S Sortase family
NECFGCCN_02354 2.5e-233 capA M Bacterial capsule synthesis protein
NECFGCCN_02355 8e-39 gcvR T UPF0237 protein
NECFGCCN_02356 9.6e-242 XK27_08635 S UPF0210 protein
NECFGCCN_02357 8.9e-130 ais G Phosphoglycerate mutase
NECFGCCN_02358 2e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NECFGCCN_02359 1.2e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
NECFGCCN_02360 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NECFGCCN_02361 9.1e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NECFGCCN_02363 0.0 dnaK O Heat shock 70 kDa protein
NECFGCCN_02365 2.6e-187 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NECFGCCN_02366 1.3e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NECFGCCN_02367 3.4e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NECFGCCN_02368 1.5e-80 hmpT S cog cog4720
NECFGCCN_02369 6.8e-53 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECFGCCN_02370 6.5e-34 nrdH O Glutaredoxin
NECFGCCN_02371 3.1e-245 pepB 3.4.11.1, 3.4.11.23 E Probably plays an important role in intracellular peptide degradation
NECFGCCN_02372 6.4e-33 iscX S Iron-sulphur cluster assembly
NECFGCCN_02373 8.7e-59 fdx C Ferredoxin, 2Fe-2S type, ISC system
NECFGCCN_02374 0.0 hscA O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU
NECFGCCN_02375 1.4e-87 hscB O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NECFGCCN_02376 2.1e-54 iscA S Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system
NECFGCCN_02377 5e-66 iscU C A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters
NECFGCCN_02378 6.1e-227 iscS 2.8.1.7 E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
NECFGCCN_02379 2.3e-84 iscR 2.8.1.7 K Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins
NECFGCCN_02380 7.6e-132 trmJ 2.1.1.200, 3.5.1.19, 6.1.1.16 J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NECFGCCN_02381 6.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
NECFGCCN_02383 4.8e-166 yohM P Belongs to the NiCoT transporter (TC 2.A.52) family
NECFGCCN_02384 1.2e-117 MA20_06510 2.7.4.1 S transport system periplasmic component
NECFGCCN_02385 6.6e-173 csiE K Stationary phase inducible protein CsiE
NECFGCCN_02386 6.8e-50 csiE K Stationary phase inducible protein CsiE
NECFGCCN_02387 1.4e-201 hcaT 1.5.1.2 EGP Major facilitator Superfamily
NECFGCCN_02388 1.6e-141 yphB 5.1.3.3 G Aldose 1-epimerase
NECFGCCN_02389 4.6e-311 E Extracellular solute-binding protein, family 5
NECFGCCN_02390 7.3e-230 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NECFGCCN_02391 6.4e-106 hisE 3.1.3.23 G TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3
NECFGCCN_02392 7.1e-133 EGP Major facilitator Superfamily
NECFGCCN_02393 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NECFGCCN_02394 7.1e-227 rodA D Belongs to the SEDS family
NECFGCCN_02395 2.1e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NECFGCCN_02396 9.9e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NECFGCCN_02397 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NECFGCCN_02398 2.2e-134 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_02399 7.5e-21 Q Methyltransferase domain
NECFGCCN_02400 1.3e-64 GnaT 2.5.1.16 K acetyltransferase
NECFGCCN_02401 3e-22 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NECFGCCN_02402 7.2e-26 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NECFGCCN_02403 1.6e-171 ydhF S Aldo keto reductase
NECFGCCN_02404 1.5e-98 K WHG domain
NECFGCCN_02405 1.5e-121 V abc transporter atp-binding protein
NECFGCCN_02406 2.1e-165 apaH 3.6.1.41 T Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NECFGCCN_02407 1.8e-65 apaG P protein affecting Mg2 Co2 transport
NECFGCCN_02408 3.4e-149 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NECFGCCN_02409 2.1e-185 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NECFGCCN_02410 8.6e-232 surA 5.2.1.8 M Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NECFGCCN_02411 0.0 lptD M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NECFGCCN_02412 4.8e-151 djlA O Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host
NECFGCCN_02413 3.4e-121 dpiA K transcriptional regulatory protein
NECFGCCN_02414 5e-293 citA 2.7.13.3 T signal transduction histidine kinase regulating citrate malate metabolism
NECFGCCN_02415 9.1e-248 cimH U Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system)
NECFGCCN_02416 3.9e-101 citG 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NECFGCCN_02417 4.3e-58 rluA 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NECFGCCN_02418 6.8e-167 togN P PFAM binding-protein-dependent transport systems inner membrane component
NECFGCCN_02419 5e-162 ycjO P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_02420 7.9e-57 kdgF S PFAM Cupin 2, conserved barrel domain protein
NECFGCCN_02421 1.7e-128 ygeA 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NECFGCCN_02422 2e-166 lysR K transcriptional regulator
NECFGCCN_02423 5.3e-242 lysA 2.7.2.4, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NECFGCCN_02424 2.4e-189 ascG K Transcriptional regulator
NECFGCCN_02425 4.8e-241 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_02426 5.2e-294 celH 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_02427 2.5e-141 uxuR K Transcriptional
NECFGCCN_02428 4.9e-87 mshD 2.3.1.189 S PFAM GCN5-related N-acetyltransferase
NECFGCCN_02429 1.6e-185 galR K transcriptional regulator
NECFGCCN_02430 0.0 aas 2.3.1.40, 6.2.1.20 I Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1
NECFGCCN_02431 1.6e-200 lplT 2.3.1.40, 6.2.1.20 U Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell
NECFGCCN_02432 1.5e-194 tas C Aldo keto reductase
NECFGCCN_02433 2.7e-32 ygdR S (Lipo)protein
NECFGCCN_02434 1e-120 ygdQ P membrane protein, terc
NECFGCCN_02435 2e-126 mutH L Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair
NECFGCCN_02436 6.4e-20
NECFGCCN_02437 1.5e-100 nudH L Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage
NECFGCCN_02438 0.0 ptsP 2.7.3.9 T Belongs to the PEP-utilizing enzyme family
NECFGCCN_02439 2.6e-171 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NECFGCCN_02440 1.1e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NECFGCCN_02441 6.2e-76 ppdA NU prepilin peptidase dependent protein A
NECFGCCN_02442 1.3e-94 ppdB U prepilin peptidase dependent protein
NECFGCCN_02443 7.6e-65 ygdB S Protein of unknown function (DUF2509)
NECFGCCN_02444 5.5e-50 ppdC NU Prepilin peptidase dependent protein c
NECFGCCN_02445 4.8e-43 M Putative cell wall binding repeat
NECFGCCN_02446 1e-07 S dextransucrase activity
NECFGCCN_02448 1.5e-189 ET ankyrin repeat
NECFGCCN_02449 0.0 eptB 2.7.8.42, 2.7.8.43 S membrane-associated metal-dependent hydrolase
NECFGCCN_02450 3.2e-188 yhjX P Major facilitator superfamily
NECFGCCN_02451 6.9e-113 yhjY N outer membrane autotransporter
NECFGCCN_02452 3.7e-105 tag 3.2.2.20 L glycosylase
NECFGCCN_02453 8.1e-81 yiaC 2.3.1.1, 2.3.1.210 K acetyltransferase
NECFGCCN_02454 0.0 bisC 1.7.2.3, 1.8.5.3 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_02455 1.8e-87 yiaD M Belongs to the ompA family
NECFGCCN_02456 7.4e-186 ptxS K transcriptional regulator
NECFGCCN_02457 6.8e-136 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
NECFGCCN_02458 4e-170 kdgK 2.7.1.13, 2.7.1.45 G 2-dehydro-3-deoxygluconokinase
NECFGCCN_02459 7e-242 G Major facilitator superfamily
NECFGCCN_02460 6.4e-179 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively
NECFGCCN_02461 2.3e-125 yiaF S exported protein
NECFGCCN_02462 9.7e-234 G transporter
NECFGCCN_02463 5.6e-46 yiaG K transcriptional regulator
NECFGCCN_02464 3.1e-33 cspA K SMART Cold shock protein
NECFGCCN_02465 3.9e-282 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
NECFGCCN_02466 1.7e-23 S PFAM Hok gef
NECFGCCN_02467 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NECFGCCN_02468 1e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NECFGCCN_02469 1.9e-44 ysaB S YsaB-like lipoprotein
NECFGCCN_02470 2.9e-182 wecH S Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
NECFGCCN_02471 2.1e-76 yiaA S Membrane
NECFGCCN_02472 4.2e-62 yiaA S Membrane
NECFGCCN_02473 1.3e-276 xylB 2.7.1.17, 2.7.1.189, 2.7.1.5, 2.7.1.51 G xylulose kinase
NECFGCCN_02474 3.6e-265 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NECFGCCN_02475 3.5e-180 xylF G D-xylose ABC transporter periplasmic substrate-binding protein
NECFGCCN_02476 1.2e-288 xylG 3.6.3.17 P import. Responsible for energy coupling to the transport system
NECFGCCN_02477 4.2e-10 xylH G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_02478 8e-90 2.4.1.60 S Glycosyltransferase group 2 family protein
NECFGCCN_02479 1.1e-108
NECFGCCN_02480 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
NECFGCCN_02481 3.6e-219 M Psort location CytoplasmicMembrane, score
NECFGCCN_02482 3.2e-223 GT4 M transferase activity, transferring glycosyl groups
NECFGCCN_02483 5e-223 rgpA GT4 M Domain of unknown function (DUF1972)
NECFGCCN_02484 4.8e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
NECFGCCN_02485 9.8e-141 rgpC GM Transport permease protein
NECFGCCN_02486 1.9e-120 K sequence-specific DNA binding
NECFGCCN_02487 2.9e-151 V ABC transporter, ATP-binding protein
NECFGCCN_02488 8e-94 S ABC-2 family transporter protein
NECFGCCN_02490 1.3e-39 ytxH S General stress protein
NECFGCCN_02491 2.1e-64 estA E GDSL-like Lipase/Acylhydrolase
NECFGCCN_02492 1.4e-99
NECFGCCN_02493 1.5e-273 sulP P Sulfate permease and related transporters (MFS superfamily)
NECFGCCN_02494 1e-232 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NECFGCCN_02495 1.7e-74 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NECFGCCN_02496 2.4e-233 tcdB S dextransucrase activity
NECFGCCN_02497 0.0 S dextransucrase activity
NECFGCCN_02498 1.4e-21 I phospholipase d transphosphatidylase
NECFGCCN_02499 1.7e-167 K transcriptional
NECFGCCN_02500 2.5e-256 EGP Major facilitator superfamily
NECFGCCN_02501 1.4e-223 ybdG M Mechanosensitive Ion channel
NECFGCCN_02502 6.1e-169 cytR 5.1.1.1 K Periplasmic binding protein LacI transcriptional regulator
NECFGCCN_02503 4.7e-70
NECFGCCN_02504 1.1e-217 S oxidoreductase
NECFGCCN_02505 2.2e-198 iolE G AP endonuclease
NECFGCCN_02506 6.2e-227 yegT G Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force
NECFGCCN_02507 1.2e-247 pheP E PFAM amino acid permease-associated region
NECFGCCN_02508 0.0 fcuA P receptor
NECFGCCN_02509 2.8e-199 S amine dehydrogenase activity
NECFGCCN_02510 4.4e-272 feaB 1.2.1.39 C belongs to the aldehyde dehydrogenase family
NECFGCCN_02511 1.1e-253 ordL E oxidoreductase
NECFGCCN_02512 1.5e-64 S enzyme of the cupin superfamily
NECFGCCN_02513 4.3e-217 hscC O Belongs to the heat shock protein 70 family
NECFGCCN_02514 1.1e-162 yocS S Transporter
NECFGCCN_02515 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NECFGCCN_02516 2.1e-13 L Helix-hairpin-helix DNA-binding motif class 1
NECFGCCN_02517 2.2e-30 S Domain of unknown function (DUF1912)
NECFGCCN_02518 1.5e-169 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NECFGCCN_02519 2.4e-101 mmuP E amino acid
NECFGCCN_02520 5.6e-106 codA 3.5.4.1 F cytosine deaminase
NECFGCCN_02521 5.6e-217 tsgA G Protein tsgA homolog
NECFGCCN_02522 2.7e-100 ppiA 5.2.1.8 M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NECFGCCN_02523 8e-21 yhfG S Protein of unknown function (DUF2559)
NECFGCCN_02524 4.2e-112 fic D cell filamentation protein Fic
NECFGCCN_02525 1.7e-99 pabA 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate synthase
NECFGCCN_02526 6.7e-234 argD 2.6.1.11, 2.6.1.17, 2.6.1.81 E aminotransferase
NECFGCCN_02527 0.0 yhfK S integral membrane protein, YccS YhfK family
NECFGCCN_02528 1.9e-115 crp K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NECFGCCN_02529 2.8e-67 yhfA O Redox protein regulator of disulfide bond formation
NECFGCCN_02530 9.5e-166 prkB 2.7.1.19 G Phosphoribulokinase
NECFGCCN_02531 2.8e-34 yheU S Belongs to the UPF0270 family
NECFGCCN_02532 2.7e-204 yheT S hydrolase of the alpha beta-hydrolase fold
NECFGCCN_02533 1.3e-292 yheS S ABC transporter
NECFGCCN_02534 2.5e-103 kefG S Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB
NECFGCCN_02535 0.0 kefB P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NECFGCCN_02536 1.2e-31 yheV S nucleic-acid-binding protein containing a Zn-ribbon domain
NECFGCCN_02537 4.7e-76 slyD 5.2.1.8 G Peptidyl-prolyl cis-trans
NECFGCCN_02538 1.3e-31 slyX S Belongs to the SlyX family
NECFGCCN_02539 6.6e-140 fkpA 5.2.1.8 M Peptidyl-prolyl cis-trans
NECFGCCN_02540 8.3e-131 yheO S protein conserved in bacteria
NECFGCCN_02541 7.2e-65 tusD P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NECFGCCN_02542 2.6e-61 tusC P Belongs to the DsrF TusC family
NECFGCCN_02543 1.4e-44 tusB P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions
NECFGCCN_02544 1.2e-64 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NECFGCCN_02545 1.1e-78 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NECFGCCN_02546 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NECFGCCN_02547 2.9e-28 hpk9 2.7.13.3 T protein histidine kinase activity
NECFGCCN_02548 1.1e-74 fumB 4.2.1.2 C Catalyzes the reversible hydration of fumarate to (S)- malate
NECFGCCN_02549 3.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NECFGCCN_02550 3.1e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NECFGCCN_02551 0.0 pepO 3.4.24.71 O Peptidase family M13
NECFGCCN_02552 6.5e-35 S Immunity protein 41
NECFGCCN_02553 0.0 M Putative cell wall binding repeat
NECFGCCN_02554 1.3e-51 uraH 3.5.2.17 P Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NECFGCCN_02555 4.8e-77 uraD 3.5.3.4, 4.1.1.97 S Ohcu decarboxylase
NECFGCCN_02556 3.6e-252 pbuX F xanthine
NECFGCCN_02557 1.1e-222 hpxO 1.14.13.113 CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NECFGCCN_02558 2.5e-164 K transcriptional regulator
NECFGCCN_02559 4e-211 vanA P Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit
NECFGCCN_02560 2.1e-182 vanB C Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1
NECFGCCN_02561 1.7e-185 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia
NECFGCCN_02562 1.5e-172 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NECFGCCN_02563 8.9e-167 K transcriptional regulator
NECFGCCN_02564 1.3e-11
NECFGCCN_02565 6.3e-207 namA 1.6.99.1 C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NECFGCCN_02566 5.4e-292 ydhS S FAD-NAD(P)-binding
NECFGCCN_02567 1.1e-220 jen EGP Major facilitator Superfamily
NECFGCCN_02568 7.9e-163 Z012_01315 EG Permeases of the drug metabolite transporter (DMT) superfamily
NECFGCCN_02569 8.8e-209 S Iron-containing redox enzyme
NECFGCCN_02570 2.9e-102 K Bacterial regulatory proteins, tetR family
NECFGCCN_02571 8.1e-91 2.3.1.128 J Acetyltransferase (GNAT) domain
NECFGCCN_02572 2.6e-220 P Major facilitator superfamily
NECFGCCN_02574 1.6e-191 gntR K transcriptional regulator
NECFGCCN_02575 1e-67 cmtB 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphotransferase System
NECFGCCN_02576 4.8e-36 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase System
NECFGCCN_02577 3.4e-212 ulaA 2.7.1.194 S transporter subunit
NECFGCCN_02578 5.8e-126 alsE 5.1.3.1 G 3-epimerase
NECFGCCN_02579 2e-77 frvA 2.7.1.194, 2.7.1.200, 2.7.1.202 G PTS IIA-like nitrogen-regulatory protein PtsN
NECFGCCN_02580 1.1e-44 fruA 2.7.1.202 G PTS system fructose-specific IIB
NECFGCCN_02581 2.7e-165 G and phosphoenolpyruvate-dependent sugar phosphotransferase system
NECFGCCN_02582 5.5e-107 yrhP E threonine efflux protein
NECFGCCN_02583 8.3e-73 ygaU GH23 S peptidoglycan-binding protein
NECFGCCN_02584 1e-241 pgtP G transporter
NECFGCCN_02585 2.4e-194 pgtC P ABC-type Fe3 transport system, periplasmic component
NECFGCCN_02586 0.0 pgtB 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NECFGCCN_02587 9.4e-199 pgtA T Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
NECFGCCN_02588 7.9e-59 yqkA S GrpB protein
NECFGCCN_02589 2e-166 K LysR substrate binding domain
NECFGCCN_02590 3e-184 C aldo keto reductase
NECFGCCN_02591 2.6e-219 C Aldo/keto reductase family
NECFGCCN_02592 3.2e-133 glcR_2 K transcriptional regulator
NECFGCCN_02593 3.3e-189 2.7.1.17, 2.7.1.189, 2.7.1.5, 2.7.1.51, 2.7.1.53 G xylulose kinase
NECFGCCN_02594 3.2e-36 fucR K transcriptional regulator
NECFGCCN_02595 1.5e-113 alsE 5.1.3.1 G 3-epimerase
NECFGCCN_02596 2e-161 rbsK 2.7.1.15, 2.7.1.4 G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NECFGCCN_02597 3.2e-237 fucP G transporter
NECFGCCN_02598 1.1e-65 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECFGCCN_02599 4.6e-296 MA20_27905 6.2.1.26, 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NECFGCCN_02600 8.9e-303 ydiF 2.8.3.1 I CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons
NECFGCCN_02601 2.7e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_02602 1.3e-120 bktB 2.3.1.9 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
NECFGCCN_02603 2.5e-225 malE G Bacterial extracellular solute-binding protein
NECFGCCN_02604 2.7e-205 malK P Part of the ABC transporter complex MalEFGK involved in maltose maltodextrin import. Responsible for energy coupling to the transport system
NECFGCCN_02605 2.8e-254 lamB M involved in the transport of maltose and maltodextrins
NECFGCCN_02606 1.9e-156 malM S maltose operon periplasmic
NECFGCCN_02607 5.6e-86 ubiC 4.1.3.40 H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway
NECFGCCN_02608 1.2e-141 ubiA 2.5.1.39 H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NECFGCCN_02609 0.0 plsB 2.3.1.15 I Belongs to the GPAT DAPAT family
NECFGCCN_02610 1.1e-57 dgkA 2.7.1.107 M Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NECFGCCN_02611 2e-106 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NECFGCCN_02612 5.6e-226 dinF V COG0534 Na -driven multidrug efflux pump
NECFGCCN_02613 2.6e-32 yjbJ S Belongs to the UPF0337 (CsbD) family
NECFGCCN_02614 1.9e-92 zur P belongs to the Fur family
NECFGCCN_02615 2.4e-97 manC S conserved protein, contains double-stranded beta-helix domain
NECFGCCN_02616 3e-181 dusA J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs
NECFGCCN_02617 1.2e-30 pspG S Phage Shock Protein G
NECFGCCN_02618 9.4e-178 qor 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NECFGCCN_02619 2.7e-263 dnaB 3.6.4.12 L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins
NECFGCCN_02620 6e-202 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NECFGCCN_02621 3e-226 tyrB 2.6.1.1, 2.6.1.57 E aminotransferase
NECFGCCN_02622 9.6e-132 aphA 3.1.3.2 S Belongs to the class B bacterial acid phosphatase family
NECFGCCN_02623 3.3e-76 yjbQ S Secondary thiamine-phosphate synthase enzyme
NECFGCCN_02624 3e-57 yjbR S protein conserved in bacteria
NECFGCCN_02625 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NECFGCCN_02626 1.8e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NECFGCCN_02627 1.1e-251 VP0557 M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella
NECFGCCN_02628 3.9e-42 L Transposase
NECFGCCN_02629 1.6e-168 L COG2801 Transposase and inactivated derivatives
NECFGCCN_02630 0.0 fepA P Receptor
NECFGCCN_02631 7.6e-64 K Transcriptional regulator
NECFGCCN_02632 0.0 E Tannase and feruloyl esterase
NECFGCCN_02634 0.0 bamA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NECFGCCN_02635 5.8e-61 iraM S Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during magnesium starvation
NECFGCCN_02636 1.4e-133 3.1.3.25 G inositol monophosphatase
NECFGCCN_02637 3.6e-172 K transcriptional regulator
NECFGCCN_02638 3e-139 MA20_22080 S of the beta-lactamase superfamily III
NECFGCCN_02639 1.3e-185 3.6.3.30 P Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system
NECFGCCN_02640 9.1e-217 S extracellular solute-binding protein, family 1
NECFGCCN_02641 9.2e-118 P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_02642 4.7e-149 P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_02643 1.6e-42 yjcB S membrane
NECFGCCN_02645 4.9e-301 yjcC 3.1.4.52 T signal transduction protein containing sensor and EAL
NECFGCCN_02646 1.2e-55 soxS K transcriptional regulator
NECFGCCN_02647 1.7e-81 soxR K redox-sensitive transcriptional activator SoxR
NECFGCCN_02648 1.7e-122 gstA 2.5.1.18 O Belongs to the GST superfamily
NECFGCCN_02649 4.7e-228 yjcD S permease
NECFGCCN_02650 3.3e-292 yjcE P NhaP-type Na H and K H antiporters
NECFGCCN_02651 4.6e-160 ywbI K transcriptional regulator
NECFGCCN_02652 3e-61 cidA S LrgA family
NECFGCCN_02653 5.7e-113 ywbG M effector of murein hydrolase
NECFGCCN_02654 1.7e-88 NU Fimbrial protein
NECFGCCN_02655 2.8e-120 sthB M chaperone
NECFGCCN_02656 0.0 NU Usher protein
NECFGCCN_02657 5.1e-80 NU Fimbrial protein
NECFGCCN_02658 1.8e-190 phfB NU Fimbrial protein
NECFGCCN_02659 8.1e-299 actP S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECFGCCN_02660 4.5e-49 yjcH S Membrane
NECFGCCN_02661 0.0 acsA 6.2.1.1 I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NECFGCCN_02662 3.5e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NECFGCCN_02663 1.9e-121 yjcO S Sel1 repeat
NECFGCCN_02664 1.6e-137 pepN 3.4.11.2 E aminopeptidase
NECFGCCN_02665 1.8e-22 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NECFGCCN_02666 1e-91 Z012_04635 K Helix-turn-helix XRE-family like proteins
NECFGCCN_02668 4.7e-51 L COG1943 Transposase and inactivated derivatives
NECFGCCN_02669 9.3e-272 G Protein of unknown function (DUF3131)
NECFGCCN_02670 5.6e-74 VPA1107 C nitric oxide dioxygenase activity
NECFGCCN_02671 0.0 T PhoQ Sensor
NECFGCCN_02672 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NECFGCCN_02673 7.5e-11 endA S DNA/RNA non-specific endonuclease
NECFGCCN_02674 3.7e-145 feaB 1.2.1.39 C belongs to the aldehyde dehydrogenase family
NECFGCCN_02675 1.5e-34 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NECFGCCN_02676 2.9e-126 5.2.1.8 O peptidylprolyl isomerase
NECFGCCN_02677 1.2e-168 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NECFGCCN_02678 6.3e-148 speD 2.5.1.16, 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NECFGCCN_02679 1.8e-62 yacL S Belongs to the UPF0231 family
NECFGCCN_02680 0.0 acnB 4.2.1.3, 4.2.1.99 C Belongs to the aconitase IPM isomerase family
NECFGCCN_02681 2.2e-192 yacH S Protein of unknown function (DUF3300)
NECFGCCN_02682 2e-138 flgK N Protein of unknown function (DUF2950)
NECFGCCN_02683 1.9e-30
NECFGCCN_02684 1e-270 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NECFGCCN_02685 3.8e-284 aceF 2.3.1.12 C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NECFGCCN_02686 0.0 aceE 1.2.4.1 C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NECFGCCN_02687 1.1e-136 pdhR K pyruvate dehydrogenase complex
NECFGCCN_02688 1.1e-245 aroP E amino acid
NECFGCCN_02689 1.9e-264 yicJ G COG2211 Na melibiose symporter and related transporters
NECFGCCN_02690 2.4e-194 abf G Belongs to the glycosyl hydrolase 43 family
NECFGCCN_02691 7.4e-155 ampE 6.3.1.10 V regulatory protein AmpE
NECFGCCN_02692 1.9e-106 ampD 3.5.1.28 V Negative regulator of beta-lactamase expression
NECFGCCN_02693 2.2e-165 nadC 2.4.2.19 H Belongs to the NadC ModD family
NECFGCCN_02694 1.9e-74 ppdD NU Belongs to the N-Me-Phe pilin family
NECFGCCN_02695 6.9e-251 hofB NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NECFGCCN_02696 8.4e-205 hofC U type II secretion system
NECFGCCN_02697 6.1e-137 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NECFGCCN_02698 1.6e-39 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NECFGCCN_02699 1.6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NECFGCCN_02700 4.4e-135 zapD D Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NECFGCCN_02701 2.6e-31 yacG 2.7.1.24 S Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NECFGCCN_02702 2.1e-64 mutT 3.6.1.55, 3.6.1.65 L belongs to the nudix hydrolase family
NECFGCCN_02703 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NECFGCCN_02704 1.3e-82 secM S Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation
NECFGCCN_02705 5.9e-174 lpxC 3.5.1.108, 4.2.1.59 M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
NECFGCCN_02706 4.6e-208 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NECFGCCN_02707 8.8e-237 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NECFGCCN_02708 1.5e-152 ftsQ 6.3.2.4 D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NECFGCCN_02709 3.8e-165 ddl 1.3.1.98, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NECFGCCN_02710 4.1e-278 murC 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NECFGCCN_02711 1.2e-194 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NECFGCCN_02712 4.3e-223 ftsW 2.4.1.227 GT28 M Peptidoglycan polymerase that is essential for cell division
NECFGCCN_02713 2.4e-245 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NECFGCCN_02714 6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NECFGCCN_02715 8.8e-229 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NECFGCCN_02716 1.2e-126 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NECFGCCN_02717 9.3e-234 gatA 3.5.1.4, 3.5.1.84, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NECFGCCN_02718 4.5e-67 ybeY S Protein of unknown function (DUF3225)
NECFGCCN_02719 2.7e-65 XK27_03610 K Acetyltransferase (GNAT) domain
NECFGCCN_02720 2.9e-207 asd 1.2.1.11 E Semialdehyde dehydrogenase, NAD binding domain
NECFGCCN_02721 7.3e-103 K transcriptional regulator
NECFGCCN_02722 1.3e-153 V multidrug resistance efflux pump
NECFGCCN_02723 2.6e-291 EGP the major facilitator superfamily
NECFGCCN_02724 6.1e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NECFGCCN_02725 3.7e-67 3.4.13.21 S protein conserved in bacteria
NECFGCCN_02726 1.8e-66
NECFGCCN_02727 6.4e-111 MA20_01125 K AraC-like ligand binding domain
NECFGCCN_02728 8.6e-130 yfeJ 6.3.5.2 F Glutamine amidotransferase
NECFGCCN_02729 1.4e-111 S Alpha beta hydrolase
NECFGCCN_02730 4.5e-11
NECFGCCN_02731 7.9e-140 ripA_2 K transcriptional regulator
NECFGCCN_02732 1.1e-133 S membrane transporter protein
NECFGCCN_02733 1.9e-188 puuE 3.5.1.41, 3.5.2.5 G deacetylase
NECFGCCN_02734 8.8e-128 hyuE 5.1.99.3 E racemase
NECFGCCN_02735 9e-130 yncC K transcriptional regulator
NECFGCCN_02736 2.9e-137 S Replication-relaxation
NECFGCCN_02738 2.3e-301 L Recombinase
NECFGCCN_02739 6.5e-154 endA F DNA RNA non-specific endonuclease
NECFGCCN_02740 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
NECFGCCN_02741 3.8e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NECFGCCN_02743 8.1e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NECFGCCN_02744 1.1e-134 G Domain of unknown function (DUF4832)
NECFGCCN_02745 9.2e-84 S membrane
NECFGCCN_02746 3e-96 P VTC domain
NECFGCCN_02747 1.2e-112 cotH M CotH kinase protein
NECFGCCN_02748 5.5e-56 yedA EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_02749 3.3e-46 pqqL S Peptidase, M16
NECFGCCN_02750 2.2e-46 FrpB2 P receptor
NECFGCCN_02751 2e-29 FrpB2 P receptor
NECFGCCN_02752 6.5e-173 EGP Major facilitator Superfamily
NECFGCCN_02753 4.1e-309 iucA 6.3.2.38 Q Siderophore biosynthesis protein
NECFGCCN_02754 4.9e-184 iucB 2.3.1.102, 6.3.2.38 J Siderophore biosynthesis protein
NECFGCCN_02755 0.0 iucC 6.3.2.39 Q Siderophore biosynthesis protein
NECFGCCN_02756 1.3e-230 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
NECFGCCN_02757 0.0 iutA M TonB dependent receptor
NECFGCCN_02758 2.2e-09 S Protein of unknown function (DUF1471)
NECFGCCN_02759 2.4e-77 K Transcriptional regulator
NECFGCCN_02760 6.1e-57 S Protein of unknown function, DUF417
NECFGCCN_02761 1.4e-22 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NECFGCCN_02762 4.8e-66 S Electron transfer DM13
NECFGCCN_02763 1.2e-44
NECFGCCN_02764 1.9e-78 pin L Resolvase, N terminal domain
NECFGCCN_02765 0.0 L Domain of unknown function (DUF4158)
NECFGCCN_02766 4.8e-100 S dextransucrase activity
NECFGCCN_02767 2.8e-97 yddQ P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_02768 2.3e-148 oppD 3.6.3.24 EP (ABC) transporter
NECFGCCN_02769 1.1e-122 gsiA_3 3.6.3.24 EP (ABC) transporter
NECFGCCN_02770 1.9e-52 S Antibiotic biosynthesis monooxygenase
NECFGCCN_02771 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NECFGCCN_02772 7.2e-98
NECFGCCN_02773 2.4e-226 yhbH S Belongs to the UPF0229 family
NECFGCCN_02774 0.0 prkA T Serine Protein Kinase
NECFGCCN_02775 2e-143 mipA M MltA-interacting protein
NECFGCCN_02776 6.3e-154 yeaE 1.1.1.21 S Aldo keto
NECFGCCN_02777 9e-172 yeaD 4.2.1.9, 5.1.3.15 G Belongs to the glucose-6-phosphate 1-epimerase family
NECFGCCN_02778 1.6e-185 gapA 1.2.1.12, 1.2.1.72 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NECFGCCN_02779 6.5e-80 msrB 1.8.4.12 O Belongs to the MsrB Met sulfoxide reductase family
NECFGCCN_02780 1.7e-44 yeaC S protein conserved in bacteria
NECFGCCN_02781 1.2e-63 yajD 2.1.1.148 L endonuclease
NECFGCCN_02782 6.2e-235 chiA1 3.2.1.14 GH18 G chitinase
NECFGCCN_02783 2.1e-117 pncA 2.7.11.1, 3.5.1.19 Q Nicotinamidase
NECFGCCN_02784 5.9e-191 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NECFGCCN_02785 0.0 sppA OU Signal peptide peptidase
NECFGCCN_02786 6.4e-99 ydjA C Nitroreductase
NECFGCCN_02787 6.9e-184 1.1.1.18, 1.1.1.369 E 2-dehydrogenase
NECFGCCN_02788 1e-190 K Transcriptional
NECFGCCN_02789 9.4e-164 mocB G ABC-type sugar transport system periplasmic component
NECFGCCN_02790 1.4e-278 mglA_1 3.6.3.17 P import. Responsible for energy coupling to the transport system
NECFGCCN_02791 1.9e-176 rbsC1 G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_02792 9.4e-55 fumA 4.2.1.2 C Catalyzes the reversible hydration of fumarate to (S)- malate
NECFGCCN_02793 1.5e-166 O Belongs to the peptidase S8 family
NECFGCCN_02794 3.4e-09 S pathogenesis
NECFGCCN_02796 5.2e-150 cbiO2 P ABC transporter, ATP-binding protein
NECFGCCN_02797 7.8e-157 P ATPase activity
NECFGCCN_02798 4.8e-132 cbiQ P cobalt transport
NECFGCCN_02799 2.4e-91 2.7.7.65 T Psort location CytoplasmicMembrane, score
NECFGCCN_02800 8e-135 S Phenazine biosynthesis protein
NECFGCCN_02801 2.6e-22 proWX P ABC transporter
NECFGCCN_02802 1e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NECFGCCN_02803 1.6e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NECFGCCN_02804 1e-179 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NECFGCCN_02805 9.3e-09 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NECFGCCN_02806 6.2e-111 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NECFGCCN_02808 5.2e-27 S unusual protein kinase
NECFGCCN_02809 3.2e-38 S granule-associated protein
NECFGCCN_02810 1.2e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_02811 2.4e-108 S hmm pf01594
NECFGCCN_02812 6.5e-64 acrF V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_02813 7.1e-33 yhdV S Protein involved in biological_process
NECFGCCN_02814 2.5e-77 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
NECFGCCN_02815 1.1e-25 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
NECFGCCN_02816 4.6e-99 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
NECFGCCN_02817 1.7e-51 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
NECFGCCN_02818 1e-162 yjlA EG membrane
NECFGCCN_02819 1.5e-158 garR 1.1.1.60 I Catalyzes the reduction of tatronate semialdehyde to D- glycerate
NECFGCCN_02820 1.6e-140 garL 4.1.2.20, 4.1.2.52, 4.1.2.53 G Belongs to the HpcH HpaI aldolase family
NECFGCCN_02821 3.2e-221 garP G transporter
NECFGCCN_02823 3.6e-280 garD 4.2.1.42, 4.2.1.7 G Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate
NECFGCCN_02824 1.4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NECFGCCN_02825 0.0 lpoA M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a)
NECFGCCN_02826 2e-67 yraN L Belongs to the UPF0102 family
NECFGCCN_02827 4.1e-104 gmhA 2.7.1.167, 2.7.1.33, 2.7.7.70, 5.3.1.28 G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
NECFGCCN_02828 1.4e-80 yraP S Periplasmic or secreted lipoprotein
NECFGCCN_02829 2.1e-183 yraQ S permease
NECFGCCN_02830 3.6e-109 yraR GM Nucleoside-diphosphate-sugar epimerases
NECFGCCN_02831 8.4e-96 yfkM 3.5.1.124 S intracellular protease
NECFGCCN_02832 6.3e-81 yhbP S Belongs to the UPF0306 family
NECFGCCN_02833 8.9e-45 yhbQ L endonuclease containing a URI domain
NECFGCCN_02834 1.7e-90 yhbS S acetyltransferase
NECFGCCN_02835 2.5e-89 yhbT I lipid carrier protein
NECFGCCN_02836 2.2e-190 yhbU O Peptidase U32
NECFGCCN_02837 8.1e-165 yhbV O protease
NECFGCCN_02838 1.5e-191 yhbW C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECFGCCN_02839 9.3e-223 mtr E Amino Acid
NECFGCCN_02840 2.8e-282 deaD 3.6.4.13 F DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation
NECFGCCN_02841 6.3e-165 nlpI S May be involved in cell division
NECFGCCN_02842 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NECFGCCN_02843 1.5e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NECFGCCN_02844 1.8e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NECFGCCN_02845 2.6e-65 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NECFGCCN_02846 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NECFGCCN_02847 2e-272 nusA K Participates in both transcription termination and antitermination
NECFGCCN_02848 1e-72 rimP S Required for maturation of 30S ribosomal subunits
NECFGCCN_02849 4.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NECFGCCN_02850 1.3e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NECFGCCN_02851 4.2e-237 XK27_04775 S hemerythrin HHE cation binding domain
NECFGCCN_02852 1e-34 M1-755 P Hemerythrin HHE cation binding domain protein
NECFGCCN_02853 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NECFGCCN_02854 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NECFGCCN_02855 2.8e-137 S haloacid dehalogenase-like hydrolase
NECFGCCN_02856 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NECFGCCN_02858 1.7e-108 6.3.2.2 H gamma-glutamylcysteine synthetase
NECFGCCN_02860 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
NECFGCCN_02861 8.2e-168 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
NECFGCCN_02863 1.9e-27
NECFGCCN_02864 7.2e-73 yciE S protein conserved in bacteria
NECFGCCN_02866 4.5e-311 3.2.1.1, 5.4.99.16 GH13 G COG0366 Glycosidases
NECFGCCN_02867 9.5e-178 yxnA S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_02869 1.3e-65 S Protein involved in biological_process
NECFGCCN_02870 1.7e-74
NECFGCCN_02871 3.4e-65 ydeI Q PFAM Bacterial OB fold (BOF) protein
NECFGCCN_02873 3.2e-74 osmC O redox protein regulator of disulfide bond formation
NECFGCCN_02874 2.2e-154 M protein conserved in bacteria
NECFGCCN_02875 7.4e-113 ET COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain
NECFGCCN_02876 6.8e-146 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NECFGCCN_02877 2.2e-168 S Membrane
NECFGCCN_02878 0.0 cbbbC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_02879 5.7e-158 oxyR_3 K transcriptional regulator
NECFGCCN_02880 1.1e-189 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_02881 4.4e-291 3.2.1.40 G Bacterial alpha-L-rhamnosidase C-terminal domain
NECFGCCN_02882 1.3e-128 K Transcriptional regulator
NECFGCCN_02884 3.9e-120 I PFAM Alpha beta hydrolase fold-3 domain protein
NECFGCCN_02885 1.9e-39 2.7.1.196, 2.7.1.205 G Phosphotransferase System
NECFGCCN_02886 4.8e-35 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
NECFGCCN_02887 9.7e-261 lacY P Sugar (and other) transporter
NECFGCCN_02888 2.6e-86 mgtC S MgtC SapB transporter
NECFGCCN_02889 2.9e-177 S AFG1-like ATPase
NECFGCCN_02890 0.0 katG 1.11.1.21 P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NECFGCCN_02891 4.8e-139 K Transcriptional regulator
NECFGCCN_02892 2.7e-52 S Putative inner membrane exporter, YdcZ
NECFGCCN_02893 5.2e-57 S Putative inner membrane exporter, YdcZ
NECFGCCN_02894 0.0 mrdA 3.4.16.4 M Catalyzes cross-linking of the peptidoglycan cell wall
NECFGCCN_02895 6.4e-131 guaA 6.3.5.2 F glutamine amidotransferase
NECFGCCN_02896 3.1e-77 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NECFGCCN_02897 1.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NECFGCCN_02898 8.3e-52 potA 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NECFGCCN_02899 1.9e-155 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NECFGCCN_02900 0.0 btuB P Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB
NECFGCCN_02901 2.6e-208 trmA 2.1.1.190, 2.1.1.35 J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)
NECFGCCN_02902 5.5e-59 yijD S membrane
NECFGCCN_02903 3.9e-108 fabR K Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer
NECFGCCN_02904 2.2e-273 sthA 1.6.1.1 C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation
NECFGCCN_02905 3.6e-171 oxyR K Transcriptional regulator
NECFGCCN_02906 2e-255 argH 2.3.1.1, 4.3.2.1 E argininosuccinate lyase
NECFGCCN_02907 6.3e-137 argB 2.3.1.1, 2.7.2.8 E Catalyzes the ATP-dependent phosphorylation of N-acetyl- L-glutamate
NECFGCCN_02908 2.6e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NECFGCCN_02909 1.6e-208 argE 3.5.1.16 E Belongs to the peptidase M20A family. ArgE subfamily
NECFGCCN_02910 6.2e-243 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NECFGCCN_02911 0.0 S bacteriocin-associated integral membrane protein
NECFGCCN_02912 2.1e-19 S Bacteriocin (Lactococcin_972)
NECFGCCN_02913 1.1e-57
NECFGCCN_02914 0.0 ctpE P E1-E2 ATPase
NECFGCCN_02915 1.8e-195 epd 1.2.1.12, 1.2.1.72 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NECFGCCN_02916 9e-212 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NECFGCCN_02917 5.6e-208 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase, class II
NECFGCCN_02918 7.5e-131 mscS M Mechanosensitive Ion channel
NECFGCCN_02919 6.4e-111 argO S Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine
NECFGCCN_02920 1.7e-118 yggE S Protein of unknown function (DUF541)
NECFGCCN_02921 8.8e-167 argP K Controls the transcription of genes involved in arginine and lysine metabolism
NECFGCCN_02922 9.9e-115 rpiA 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NECFGCCN_02923 3.3e-228 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NECFGCCN_02924 9.6e-109 fthC 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NECFGCCN_02925 2.7e-44 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NECFGCCN_02926 5.1e-107 ygfB S Belongs to the UPF0149 family
NECFGCCN_02927 4.2e-250 pepP 3.4.11.9 E aminopeptidase
NECFGCCN_02928 2.3e-215 ubiH CH hydroxylase
NECFGCCN_02929 4e-223 visC CH ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6
NECFGCCN_02930 5.5e-211 gcvT 2.1.2.10 H The glycine cleavage system catalyzes the degradation of glycine
NECFGCCN_02931 3.6e-64 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NECFGCCN_02932 0.0 gcvP 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NECFGCCN_02933 1.2e-129 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
NECFGCCN_02934 1.6e-85 scsD CO COG0526 Thiol-disulfide isomerase and thioredoxins
NECFGCCN_02935 5.4e-107 bdbD O DSBA-like thioredoxin domain
NECFGCCN_02936 8.2e-236 dsbD 1.8.1.8 CO Disulphide bond corrector protein DsbC
NECFGCCN_02937 4.8e-55 murQ 4.2.1.126 S Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NECFGCCN_02938 0.0 mqo 1.1.5.4 C malate quinone oxidoreductase
NECFGCCN_02939 8e-163 mdcR K Transcriptional regulator
NECFGCCN_02940 2.5e-153 mdcH 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NECFGCCN_02941 2.4e-110 mdcG 2.7.7.66 H Phosphoribosyl-dephospho-CoA transferase MdcG
NECFGCCN_02942 5.4e-162 mdcF S auxin efflux carrier
NECFGCCN_02943 7e-139 mdcE 4.1.1.87 I malonate decarboxylase gamma subunit
NECFGCCN_02944 2e-149 mdcD 4.1.1.87 I Beta subunit
NECFGCCN_02945 3.4e-46 mdcC C Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism
NECFGCCN_02946 3.1e-26 mdcB 2.4.2.52 H Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase
NECFGCCN_02949 2.6e-154 ydiJ C Fad linked oxidase
NECFGCCN_02950 1.2e-97 ydiJ C Fad linked oxidase
NECFGCCN_02951 2.7e-197 ydiK S ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated
NECFGCCN_02952 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NECFGCCN_02953 5.2e-153 ydiA 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation
NECFGCCN_02954 5e-30 aroH 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NECFGCCN_02955 2.6e-68 cysW_1 P ABC-type Fe3 transport system permease component
NECFGCCN_02956 1.5e-112 thiN 2.7.6.2 H thiamine pyrophosphokinase
NECFGCCN_02957 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NECFGCCN_02958 1.7e-159 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NECFGCCN_02960 2.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NECFGCCN_02961 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NECFGCCN_02962 6.8e-142 tatD L Hydrolase, tatd
NECFGCCN_02963 1.1e-23 yccU S CoA-binding protein
NECFGCCN_02964 1.9e-300 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NECFGCCN_02965 6e-127 3.1.3.48 T Protein tyrosine serine phosphatase
NECFGCCN_02966 1.6e-172 ybiS M ErfK YbiS YcfS YnhG family protein
NECFGCCN_02967 1.2e-126 gmuR K GntR family
NECFGCCN_02968 1.1e-272 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_02969 1.5e-195 ybiR P Citrate transporter
NECFGCCN_02970 3.3e-80 mntR K transcriptional regulator
NECFGCCN_02971 5.8e-16
NECFGCCN_02972 1.7e-301 ybiP 2.7.8.42, 2.7.8.43 S membrane-associated metal-dependent hydrolase
NECFGCCN_02973 8.6e-90 ompX M PFAM virulence-related outer membrane protein
NECFGCCN_02974 4.2e-153 rhtA S permease DMT superfamily
NECFGCCN_02975 6.7e-87 dps P During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
NECFGCCN_02976 1.1e-135 glnH ET belongs to the bacterial solute-binding protein 3 family
NECFGCCN_02977 7.1e-113 glnP P (ABC) transporter
NECFGCCN_02978 9.1e-130 glnQ E (ABC) transporter
NECFGCCN_02979 0.0 ybiO M mechanosensitive ion channel
NECFGCCN_02980 9e-175 rlmF 2.1.1.181 J Specifically methylates the adenine in position 1618 of 23S rRNA
NECFGCCN_02981 6.4e-116 IV02_24660 S Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family
NECFGCCN_02982 5.8e-34 mcbA S colanic acid metabolic process
NECFGCCN_02983 4.4e-45 ybiI T DnaK suppressor protein
NECFGCCN_02984 1.8e-35 ybiJ S protein involved in
NECFGCCN_02985 3.1e-133 ybiB 2.4.2.18 E Glycosyl transferase
NECFGCCN_02986 2.4e-41 livF P Branched-chain amino acid transport
NECFGCCN_02987 3.8e-26
NECFGCCN_02988 5e-145 fliY_2 ET Belongs to the bacterial solute-binding protein 3 family
NECFGCCN_02989 4e-142 glnQ 3.6.3.21 E (ABC) transporter
NECFGCCN_02990 1.1e-130 glnM P (ABC) transporter
NECFGCCN_02991 5.3e-119 glnP P (ABC) transporter
NECFGCCN_02992 3.3e-132 ecpE NU Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
NECFGCCN_02993 0.0 yagW S Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Tip pilus adhesin, which is required for assembly of EcpA into fibers (By similarity)
NECFGCCN_02994 0.0 ecpC NU Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
NECFGCCN_02995 3e-119 ecpB M Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
NECFGCCN_02996 9.2e-96 matB S Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Major subunit of the fimbria
NECFGCCN_02997 1.9e-92 matA K Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition
NECFGCCN_02998 4.6e-149 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NECFGCCN_02999 9.3e-175 phnD P Phosphonate ABC transporter
NECFGCCN_03000 4.7e-157 phnE_2 P Phosphonate ABC transporter
NECFGCCN_03001 5.7e-158 phnE 3.6.1.63 P Phosphonate ABC transporter
NECFGCCN_03002 1.2e-58 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NECFGCCN_03003 3.7e-197 yjbB G Permeases of the major facilitator superfamily
NECFGCCN_03004 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NECFGCCN_03005 3.1e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
NECFGCCN_03006 9.2e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NECFGCCN_03010 3.3e-155 cjaA ET ABC transporter substrate-binding protein
NECFGCCN_03011 3.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_03012 5.1e-106 P ABC transporter (Permease
NECFGCCN_03013 8.6e-114 papP P ABC transporter (Permease
NECFGCCN_03014 3e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NECFGCCN_03015 1.5e-86 zntB P Zinc transport protein zntB
NECFGCCN_03016 2.7e-121 glcR K transcriptional regulator
NECFGCCN_03017 3.9e-188 ydgJ 1.1.1.371 S oxidoreductase
NECFGCCN_03018 4.2e-29
NECFGCCN_03019 4.9e-118
NECFGCCN_03020 4.8e-93 P ABC transporter (permease)
NECFGCCN_03021 1e-182 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NECFGCCN_03022 7.8e-146 metQ_2 P NLPA lipoprotein
NECFGCCN_03023 4.8e-221 ykrV3 2.6.1.83 E Aminotransferase class I and II
NECFGCCN_03024 2.3e-73 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NECFGCCN_03025 3.8e-22 plnP V CAAX protease self-immunity
NECFGCCN_03026 0.0 S dextransucrase activity
NECFGCCN_03027 3e-182 K Probable Zinc-ribbon domain
NECFGCCN_03028 1.2e-56 gepA S Protein of unknown function (DUF4065)
NECFGCCN_03030 2e-80 M Pilin isopeptide linkage domain protein
NECFGCCN_03031 2.4e-66 XK27_09825 V abc transporter atp-binding protein
NECFGCCN_03032 5.7e-119 yvfS V Transporter
NECFGCCN_03033 9.5e-37
NECFGCCN_03034 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
NECFGCCN_03035 5.9e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NECFGCCN_03036 1.5e-233 sufD O assembly protein SufD
NECFGCCN_03037 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NECFGCCN_03038 5.7e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
NECFGCCN_03039 6.6e-123 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NECFGCCN_03040 2.4e-17 S Protein of unknown function (DUF3021)
NECFGCCN_03041 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NECFGCCN_03042 4.3e-270 glnP P ABC transporter
NECFGCCN_03045 3.4e-53 gutM K Glucitol operon activator
NECFGCCN_03046 1.3e-137 srlR K Transcriptional
NECFGCCN_03047 8.1e-174 gutQ 5.3.1.13 M Arabinose 5-phosphate isomerase
NECFGCCN_03048 2.9e-282 norR KT transcriptional regulator
NECFGCCN_03049 1.6e-202 norV 1.6.3.4 C uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
NECFGCCN_03050 1.3e-277 urtB E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_03051 1.2e-246 urtA E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NECFGCCN_03052 2.3e-217 yxjG 2.1.1.14 E methionine synthase
NECFGCCN_03053 4.8e-72 XK27_05625 P Rhodanese
NECFGCCN_03054 3.1e-198 ftrA K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
NECFGCCN_03055 3.1e-33 S Domain of unknown function (DUF4177)
NECFGCCN_03056 2.7e-76 K Acetyltransferase (GNAT) domain
NECFGCCN_03058 3.2e-101 lacI K binds specific sites in lac operon resulting in DNA looping between the operators
NECFGCCN_03059 1.8e-31 dksA1 T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression
NECFGCCN_03060 1e-246 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NECFGCCN_03061 1.6e-247 pbuO S permease
NECFGCCN_03062 1e-75 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NECFGCCN_03063 1.1e-87 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
NECFGCCN_03064 7.4e-212 brpA K Transcriptional
NECFGCCN_03065 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
NECFGCCN_03066 3.5e-195 nusA K Participates in both transcription termination and antitermination
NECFGCCN_03067 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NECFGCCN_03068 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NECFGCCN_03069 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NECFGCCN_03070 1.2e-97 yvdD 3.2.2.10 S Belongs to the LOG family
NECFGCCN_03071 1.7e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NECFGCCN_03072 1.2e-64 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NECFGCCN_03073 2.8e-76 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NECFGCCN_03074 4.4e-144 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NECFGCCN_03075 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NECFGCCN_03076 2.1e-47 tdk 2.7.1.21 F thymidine kinase
NECFGCCN_03077 5.6e-228 noxE P NADH oxidase
NECFGCCN_03078 3e-50 zntB P Zinc transport protein zntB
NECFGCCN_03079 1.2e-255 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NECFGCCN_03080 1.6e-179 ttcA 6.3.4.19 J Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system
NECFGCCN_03081 3.1e-72 uspF T Belongs to the universal stress protein A family
NECFGCCN_03082 1.5e-32 S KTSC domain
NECFGCCN_03083 1.5e-58 ompN M Belongs to the Gram-negative porin family
NECFGCCN_03084 2.7e-157 5.2.1.8 G hydrolase
NECFGCCN_03085 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECFGCCN_03086 1.1e-196 MA20_36090 S Protein of unknown function (DUF2974)
NECFGCCN_03087 1.9e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_03088 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NECFGCCN_03089 3e-98 cfa 2.1.1.317, 2.1.1.79 M synthase
NECFGCCN_03090 1.6e-86 outB S Type II secretion system protein B
NECFGCCN_03091 5.2e-60 outS S TIGRFAM lipoprotein, PulS OutS family
NECFGCCN_03092 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)
NECFGCCN_03093 0.0 fhuA P Receptor
NECFGCCN_03094 1.1e-144 fhuC 3.6.3.34 HP ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NECFGCCN_03095 2.7e-160 fhuD P ABC-type Fe3 -hydroxamate transport system, periplasmic component
NECFGCCN_03096 0.0 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_03097 1.2e-61 F COG0402 Cytosine deaminase and related metal-dependent hydrolases
NECFGCCN_03098 4.4e-191 C Belongs to the iron ascorbate-dependent oxidoreductase family
NECFGCCN_03099 9.7e-161 K transcriptional regulator
NECFGCCN_03100 1.5e-230 EGP Permeases of the major facilitator superfamily
NECFGCCN_03101 6.6e-07 K luxR family
NECFGCCN_03102 6.2e-90 S DinB family
NECFGCCN_03103 1.2e-49 cigR S response to cobalt ion
NECFGCCN_03104 9.3e-178 gsiA_8 P Belongs to the ABC transporter superfamily
NECFGCCN_03105 1.6e-174 oppD 3.6.3.24 P Belongs to the ABC transporter superfamily
NECFGCCN_03106 5e-168 appC P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NECFGCCN_03107 4.8e-70 appB P ABC-type dipeptide oligopeptide nickel transport systems, permease
NECFGCCN_03108 8.3e-51 S LemA family
NECFGCCN_03109 1.6e-76 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NECFGCCN_03110 5.6e-209 seuB I acyl-CoA dehydrogenase
NECFGCCN_03111 2.8e-255 ygcS EGP Major facilitator superfamily
NECFGCCN_03112 3e-159 metQ_1 P ABC transporter substrate-binding protein
NECFGCCN_03113 4e-122 metI U ABC transporter (permease)
NECFGCCN_03114 1.3e-182 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NECFGCCN_03115 9.6e-277 soxA 1.14.14.28 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECFGCCN_03116 9.3e-75 S oxidoreductase
NECFGCCN_03117 1e-28 L cog cog3677
NECFGCCN_03118 1.6e-79 Q DSBA-like thioredoxin domain
NECFGCCN_03119 1.7e-189 IQ PFAM AMP-dependent synthetase and ligase
NECFGCCN_03120 1.6e-43 fcy21 F Belongs to the purine-cytosine permease (2.A.39) family
NECFGCCN_03121 4.7e-83 T signal transduction protein containing sensor and EAL
NECFGCCN_03122 5.8e-15 L Integrase core domain
NECFGCCN_03123 5.7e-139 S X-Pro dipeptidyl-peptidase (S15 family)
NECFGCCN_03124 3.4e-85 tnpR L Resolvase, N terminal domain
NECFGCCN_03125 2.2e-131 L Transposase
NECFGCCN_03126 6.1e-243 L Tn3 transposase DDE domain
NECFGCCN_03127 1.8e-20 S Protein of unknown function (DUF1173)
NECFGCCN_03130 1.4e-56 dsbC 5.3.4.1 O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NECFGCCN_03131 4.5e-56 M lytic transglycosylase activity
NECFGCCN_03132 1.3e-27 L membrane
NECFGCCN_03133 4.5e-21
NECFGCCN_03134 1.3e-130 S Putative helicase
NECFGCCN_03135 2e-224 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NECFGCCN_03136 3.8e-66 foxA P Receptor
NECFGCCN_03137 2.2e-53 foxA P Receptor
NECFGCCN_03138 1.9e-112 emtA GH23 M Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain
NECFGCCN_03139 1.5e-169 ldcA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NECFGCCN_03140 0.0 nhaP2 P K( ) H( ) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels
NECFGCCN_03141 1.4e-203 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NECFGCCN_03142 2e-252 dadA 1.4.5.1 E Oxidative deamination of D-amino acids
NECFGCCN_03143 5.7e-307 spoVR S SpoVR family
NECFGCCN_03144 5.5e-135 fadR K Multifunctional regulator of fatty acid metabolism
NECFGCCN_03145 1.5e-252 nhaB P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NECFGCCN_03146 1.2e-97 dsbB O Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NECFGCCN_03147 1.1e-61 P protein domain, possibly involved in tellurite resistance
NECFGCCN_03148 5.5e-85 ycgN S Belongs to the UPF0260 family
NECFGCCN_03149 1.9e-121 ycgM Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NECFGCCN_03150 2.1e-45 ycgL S YcgL domain-containing protein
NECFGCCN_03151 3.4e-113 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NECFGCCN_03152 1.1e-144 minD D Belongs to the ParA family
NECFGCCN_03153 3.9e-41 minE D Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NECFGCCN_03154 2.2e-207 rnd 3.1.13.5 J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NECFGCCN_03155 0.0 fadD 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NECFGCCN_03156 3.9e-99 yeaY M Outer Membrane Lipoprotein
NECFGCCN_03157 8.5e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NECFGCCN_03158 0.0 dinG 3.6.4.12 KL helicase
NECFGCCN_03159 1.5e-57 yoaB J Translation Initiation Inhibitor YjgF Family
NECFGCCN_03160 1.1e-21 yoaH S Belongs to the UPF0181 family
NECFGCCN_03161 6.7e-251 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NECFGCCN_03162 1.2e-103 nudL L NUDIX hydrolase
NECFGCCN_03163 2.9e-262 sdaA 4.3.1.17 E l-serine dehydratase
NECFGCCN_03164 2e-262 adrB 3.1.4.52 T EAL domain
NECFGCCN_03165 4.1e-276 yoaE P membrane protein, terc
NECFGCCN_03166 2.2e-163 manX 2.7.1.191 G pts system
NECFGCCN_03167 3.4e-133 manY G pts system
NECFGCCN_03168 3.5e-157 manZ G PTS system mannose fructose sorbose family IID component
NECFGCCN_03169 7.7e-74 yobD S UPF0266 membrane protein
NECFGCCN_03170 5.2e-96 mntP P Probably functions as a manganese efflux pump
NECFGCCN_03171 4.1e-147 rrmA 2.1.1.187 Q Methyl-transferase
NECFGCCN_03172 0.0 ftsI 3.4.16.4 M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum
NECFGCCN_03173 1.1e-32 cspC K Cold shock
NECFGCCN_03174 6.4e-42 yebO S YebO-like protein
NECFGCCN_03175 5.9e-33 yobH S YobH-like protein
NECFGCCN_03176 3.3e-141 kdgR K transcriptional regulator
NECFGCCN_03177 5e-238 yebQ EGP Major facilitator superfamily
NECFGCCN_03178 2.1e-152 htpX O Belongs to the peptidase M48B family
NECFGCCN_03179 0.0 prc 3.4.21.102 M Belongs to the peptidase S41A family
NECFGCCN_03180 2e-86 proQ T RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NECFGCCN_03181 4e-85 yebR 1.8.4.14 T GAF domain-containing protein
NECFGCCN_03182 4.1e-234 yebS S paraquat-inducible protein A
NECFGCCN_03183 0.0 yebT Q paraquat-inducible protein b
NECFGCCN_03184 8.1e-260 rsmF 2.1.1.176, 2.1.1.178 J Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NECFGCCN_03185 3.4e-41 yebV S Protein of unknown function (DUF1480)
NECFGCCN_03186 2.6e-31 yebW S Protein of unknown function (DUF1482)
NECFGCCN_03187 1.1e-118 pphA 3.1.3.16 T Serine Threonine protein
NECFGCCN_03188 7.9e-164 virK S protein conserved in bacteria
NECFGCCN_03190 1.3e-54 yebY S Protein of unknown function (DUF2511)
NECFGCCN_03191 9.2e-145 yebZ P copper resistance protein
NECFGCCN_03192 1e-55 yobA S Resistance protein
NECFGCCN_03193 1.3e-34 holE 2.7.7.7 L DNA polymerase III
NECFGCCN_03194 1.1e-124 exoX L 3'-5' exonuclease activity on single or double-strand DNA
NECFGCCN_03195 0.0 ptrB 3.4.21.83 E Protease II
NECFGCCN_03196 3.6e-101 yebE S Protein of unknown function (DUF533)
NECFGCCN_03197 3.7e-36 yebG S protein conserved in bacteria
NECFGCCN_03198 5e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NECFGCCN_03199 1.4e-113 eda 4.1.2.14, 4.1.3.42 G Aldolase
NECFGCCN_03200 0.0 edd 4.2.1.12 EG Belongs to the IlvD Edd family
NECFGCCN_03201 6.8e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NECFGCCN_03202 2.1e-147 hexR K transcriptional regulator
NECFGCCN_03203 4.3e-264 pyk 2.7.1.40 G Belongs to the pyruvate kinase family
NECFGCCN_03204 1.9e-187 lpxM 2.3.1.241, 2.3.1.242, 2.3.1.243 M Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A
NECFGCCN_03205 2.6e-247 yebA M COG0739 Membrane proteins related to metalloendopeptidases
NECFGCCN_03206 4.4e-156 znuA P ABC-type Zn2 transport system, periplasmic component surface adhesin
NECFGCCN_03207 6.8e-136 znuC P Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system
NECFGCCN_03208 2.9e-113 znuB P ABC 3 transport family
NECFGCCN_03209 9.6e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NECFGCCN_03210 1.3e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NECFGCCN_03211 1.1e-87 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NECFGCCN_03212 3.7e-126 yebC K transcriptional regulatory protein
NECFGCCN_03213 4.2e-77 nudB 2.3.1.181, 3.6.1.13, 3.6.1.55, 3.6.1.67 L dihydroneopterin triphosphate
NECFGCCN_03214 0.0 aspS 6.1.1.12 J L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NECFGCCN_03215 2.8e-102 yecD Q Hydrolase
NECFGCCN_03216 5.8e-157 yecE S Protein of unknown function DUF72
NECFGCCN_03217 4.9e-69 yecN S relative of glutathione S-transferase, MAPEG superfamily
NECFGCCN_03218 6.1e-137 cmoA Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)
NECFGCCN_03219 1e-195 cmoB J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs
NECFGCCN_03220 5e-131 cutC P Participates in the control of copper homeostasis
NECFGCCN_03221 6.6e-107 yecM S protein conserved in bacteria
NECFGCCN_03222 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NECFGCCN_03223 1.7e-223 yesR 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NECFGCCN_03224 7.5e-286 G Major Facilitator
NECFGCCN_03225 2.6e-68 uspC T Required for resistance to DNA-damaging agents
NECFGCCN_03226 6.8e-278 otsA 2.4.1.15, 2.4.1.347 GT20 G Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NECFGCCN_03227 1.6e-140 otsB 2.4.1.15, 2.4.1.347, 3.1.3.12 GT20 G Removes the phosphate from trehalose 6-phosphate to produce free trehalose
NECFGCCN_03228 1.4e-157 araH G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_03229 2.5e-286 araG 3.6.3.17 P Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system
NECFGCCN_03230 6e-185 araF G l-arabinose-binding periplasmic protein
NECFGCCN_03231 1.7e-85 ftnA 1.16.3.2 P Iron-storage protein
NECFGCCN_03232 6.7e-279 yihO3 G Major Facilitator
NECFGCCN_03233 4.6e-36 yecJ S Protein of unknown function (DUF2766)
NECFGCCN_03234 3.4e-253 EGP Major facilitator Superfamily
NECFGCCN_03235 6.6e-116 YPO1991 5.3.1.26, 5.3.1.6 G isomerase
NECFGCCN_03236 3.9e-87 ftnA 1.16.3.2 P Iron-storage protein
NECFGCCN_03237 2.3e-29 yecH S Protein of unknown function (DUF2492)
NECFGCCN_03238 1.2e-195 tyrP E amino acid
NECFGCCN_03239 3.6e-120 yecA C Belongs to the UPF0149 family
NECFGCCN_03240 3.6e-144 dapA5 4.3.3.7 EM Belongs to the DapA family
NECFGCCN_03244 1.3e-74 GM domain, Protein
NECFGCCN_03245 1.6e-263 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NECFGCCN_03246 2.2e-45
NECFGCCN_03247 1.6e-23 S dextransucrase activity
NECFGCCN_03249 2.5e-28 S dextransucrase activity
NECFGCCN_03250 1.6e-41 S dextransucrase activity
NECFGCCN_03251 2.6e-123 prkC 2.7.11.1 KLT serine threonine protein kinase
NECFGCCN_03252 1.2e-103 kcsA P Ion transport protein
NECFGCCN_03253 8.6e-117 yvqF S Membrane
NECFGCCN_03254 1.9e-170 vraS 2.7.13.3 T Histidine kinase
NECFGCCN_03255 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECFGCCN_03256 6.5e-115 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
NECFGCCN_03257 7.1e-164 feaR K transcriptional regulator
NECFGCCN_03258 5.7e-47 ydbL S protein conserved in bacteria
NECFGCCN_03259 4.3e-23 ynbE S (Lipo)protein
NECFGCCN_03260 0.0 ydbH S Dicarboxylate transport
NECFGCCN_03261 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NECFGCCN_03262 1.7e-94 ypmS S Protein conserved in bacteria
NECFGCCN_03263 1.4e-156 ypmR E COG2755 Lysophospholipase L1 and related esterases
NECFGCCN_03264 4.4e-144 DegV S DegV family
NECFGCCN_03265 3.9e-301 recN L May be involved in recombinational repair of damaged DNA
NECFGCCN_03266 7.9e-70 yccU 2.5.1.49 S CoA-binding protein
NECFGCCN_03267 2.3e-81 mgsA 4.2.3.3 G Methylglyoxal synthase
NECFGCCN_03268 0.0 helD 3.6.4.12 L DNA helicase
NECFGCCN_03269 2.1e-76 yccF S Membrane
NECFGCCN_03270 0.0 yccS S Membrane
NECFGCCN_03271 2.4e-99 sxy K regulator of competence-specific genes
NECFGCCN_03272 2e-83 sulA D Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
NECFGCCN_03273 6e-194 ompA M Belongs to the ompA family
NECFGCCN_03274 2.5e-77 matP D Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain
NECFGCCN_03275 0.0 ycbZ O Belongs to the peptidase S16 family
NECFGCCN_03276 1.1e-97 fabA 4.2.1.59, 5.3.3.14 I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length
NECFGCCN_03277 2.9e-99 ymbA S protein conserved in bacteria
NECFGCCN_03278 0.0 pqiB Q paraquat-inducible protein b
NECFGCCN_03279 1.3e-235 pqiA S paraquat-inducible protein A
NECFGCCN_03280 0.0 uup S ABC transporter C-terminal domain
NECFGCCN_03281 6.4e-240 rlmL 2.1.1.173, 2.1.1.191, 2.1.1.264, 2.1.1.72 J Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NECFGCCN_03283 7.9e-64 entF 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NECFGCCN_03284 2.7e-54 entF 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NECFGCCN_03285 9.1e-35 ybdZ P PFAM MbtH domain protein
NECFGCCN_03286 7.3e-241 fes P esterase
NECFGCCN_03287 7.5e-121 mtnN 3.2.2.9 F Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NECFGCCN_03288 5.3e-289 dgt 3.1.5.1 F dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs
NECFGCCN_03289 4.9e-252 degP 1.3.1.74, 3.4.21.107 M Belongs to the peptidase S1C family
NECFGCCN_03290 4.1e-215 cdaR KT regulator
NECFGCCN_03291 3.2e-65 yaeH S Belongs to the UPF0325 family
NECFGCCN_03292 7.2e-123 dapD 2.3.1.117, 2.3.1.89 E Belongs to the transferase hexapeptide repeat family
NECFGCCN_03293 0.0 glnD 2.7.7.59 O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NECFGCCN_03294 2.5e-149 map 3.4.11.18 E Methionine aminopeptidase
NECFGCCN_03295 1.3e-131 rpsB J ribosomal protein
NECFGCCN_03296 6.1e-149 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NECFGCCN_03297 1.6e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NECFGCCN_03298 2.2e-75 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NECFGCCN_03299 2.9e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NECFGCCN_03300 9.5e-141 uppS 2.5.1.31 H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide
NECFGCCN_03301 4.4e-146 cdsA 2.7.7.41 I Belongs to the CDS family
NECFGCCN_03302 4.6e-252 rseP 3.4.21.107 M zinc metalloprotease
NECFGCCN_03303 0.0 bamA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NECFGCCN_03304 9.6e-75 skp M Belongs to the skp family
NECFGCCN_03305 4.9e-113 lpxD 2.3.1.191 M as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NECFGCCN_03306 8.4e-81 fabZ 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NECFGCCN_03307 9.1e-83 lpxA 2.3.1.129 M involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NECFGCCN_03308 1.1e-214 lpxB 2.4.1.182 GT19 M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NECFGCCN_03309 2.2e-105 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NECFGCCN_03310 0.0 dnaE 2.7.7.7 L DNA polymerase
NECFGCCN_03311 4.2e-175 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NECFGCCN_03312 0.0 ldcC 4.1.1.17, 4.1.1.18, 4.1.1.19 E decarboxylase
NECFGCCN_03313 3e-71 yaeR E glyoxalase bleomycin resistance protein dioxygenase
NECFGCCN_03314 1.4e-40 tilS 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NECFGCCN_03315 1.9e-50 yjdL U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_03316 1.6e-216 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NECFGCCN_03317 7.9e-27 narH 1.7.5.1 C nitrate reductase beta subunit
NECFGCCN_03318 2e-113 narJ 1.7.5.1 C nitrate reductase molybdenum cofactor assembly chaperone
NECFGCCN_03319 2.2e-125 narI 1.7.5.1 C nitrate reductase, gamma subunit
NECFGCCN_03320 7.5e-52 sseB S enhanced serine sensitivity protein SseB
NECFGCCN_03322 2.6e-163 sseA 2.8.1.1, 2.8.1.2 P sulfurtransferase
NECFGCCN_03323 6.2e-196 yfhM P Large extracellular alpha-helical protein
NECFGCCN_03324 8.2e-142 yfhM P Large extracellular alpha-helical protein
NECFGCCN_03325 3.9e-154 czcD P cation diffusion facilitator family transporter
NECFGCCN_03326 5.9e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NECFGCCN_03327 9.5e-189 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NECFGCCN_03329 1.4e-32
NECFGCCN_03330 2.8e-97
NECFGCCN_03331 8.1e-57 S ABC-2 type transporter
NECFGCCN_03332 5.7e-158 V AAA domain, putative AbiEii toxin, Type IV TA system
NECFGCCN_03334 9.5e-139 C Iron-sulfur cluster-binding domain
NECFGCCN_03335 2e-76 pqqC 1.3.3.11 I radical SAM domain protein
NECFGCCN_03336 7.6e-44 yphJ 4.1.1.44 I decarboxylase
NECFGCCN_03337 1.1e-133 tam 2.1.1.144, 2.1.1.197 S Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate
NECFGCCN_03338 9.6e-46
NECFGCCN_03339 2.7e-203 EGP MFS-type transporter
NECFGCCN_03340 8.1e-70 yycE 3.4.21.26, 5.3.1.24 E PFAM Glyoxalase bleomycin resistance protein dioxygenase
NECFGCCN_03341 2.7e-200 yjiJ EGP Major facilitator Superfamily
NECFGCCN_03342 2.1e-149 gltR_2 K LysR substrate binding domain
NECFGCCN_03343 1.2e-70 S Protein involved in biological_process
NECFGCCN_03345 8.7e-60 S Type VI secretion system effector
NECFGCCN_03346 5.1e-144 gspL U involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NECFGCCN_03347 7.1e-78 gspM U involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NECFGCCN_03348 1.4e-37 S Type II secretion system (T2SS), protein N
NECFGCCN_03349 1.1e-144 pppA 3.4.23.43 NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NECFGCCN_03350 0.0 hrpB 3.6.4.13 L ATP-dependent helicase
NECFGCCN_03351 2.9e-96 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NECFGCCN_03352 4.3e-132 sfsA S Belongs to the SfsA family
NECFGCCN_03353 3.5e-79 dksA T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression
NECFGCCN_03354 3.9e-167 gluQ J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
NECFGCCN_03355 9.1e-256 pcnB 2.7.7.19, 2.7.7.72 H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control
NECFGCCN_03356 2.3e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NECFGCCN_03357 2.7e-143 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NECFGCCN_03358 5.3e-153 panC 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NECFGCCN_03359 1.6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NECFGCCN_03360 5.8e-233 yadE 3.5.1.41 G Polysaccharide deacetylase
NECFGCCN_03361 4.2e-77 yadI G IIa component
NECFGCCN_03362 4.8e-137 yadH V Transport Permease Protein
NECFGCCN_03363 5.4e-167 yadG V (ABC) transporter
NECFGCCN_03364 6e-128 can 4.2.1.1 P Reversible hydration of carbon dioxide
NECFGCCN_03365 6.1e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NECFGCCN_03366 0.0 gcd 1.1.5.2 G Dehydrogenase
NECFGCCN_03367 4.4e-286 cueO Q Multi-copper
NECFGCCN_03368 2.3e-57 yacC S Type II secretion system pilotin lipoprotein (PulS_OutS)
NECFGCCN_03369 1.5e-57
NECFGCCN_03370 1.4e-23 S oxidoreductase
NECFGCCN_03373 4.3e-49 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NECFGCCN_03374 1e-243 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NECFGCCN_03375 1.7e-13
NECFGCCN_03376 4.2e-55 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NECFGCCN_03377 1.2e-18 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NECFGCCN_03378 2.4e-178 hemB 4.2.1.24 H Belongs to the ALAD family
NECFGCCN_03379 1.1e-222 ampH 3.4.16.4 V This protein has no known enzymatic function
NECFGCCN_03380 9.8e-97 3.5.1.19 Q Isochorismatase
NECFGCCN_03381 5.5e-228 sbmA I In Escherichia coli SbmA is involved in uptake of microcin J25
NECFGCCN_03382 3e-201 yaiW S Lipoprotein
NECFGCCN_03383 3.7e-48 yaiY S Protein of unknown function (DUF2755)
NECFGCCN_03384 6.1e-31 yaiZ S Protein of unknown function (DUF2754)
NECFGCCN_03385 5e-204 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NECFGCCN_03386 5.6e-121 S extensin
NECFGCCN_03387 3.8e-213 pmrA EGP Major facilitator Superfamily
NECFGCCN_03388 2.5e-37 iraP S Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway
NECFGCCN_03389 3.4e-261 phoA 3.1.3.1, 3.1.3.39 P Belongs to the alkaline phosphatase family
NECFGCCN_03390 2.1e-25 psiF S Phosphate starvation-inducible protein, PSIF
NECFGCCN_03391 4e-142 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NECFGCCN_03392 1.1e-77 yaiI S Belongs to the UPF0178 family
NECFGCCN_03393 2.2e-83 yba2 S protein conserved in bacteria
NECFGCCN_03394 1.5e-92 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NECFGCCN_03395 1.2e-28 yaiA S YaiA protein
NECFGCCN_03396 1.4e-108 aroM E AroM protein
NECFGCCN_03397 8.5e-47 ppnP 2.4.2.1, 2.4.2.2 S Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions
NECFGCCN_03398 5.8e-166 rdgC L May be involved in recombination
NECFGCCN_03399 2.2e-173 mak 2.7.1.4, 2.7.1.59 GK ROK family
NECFGCCN_03400 0.0 sbcC L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NECFGCCN_03401 5.3e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NECFGCCN_03402 2.8e-128 K phosphate regulon transcriptional regulatory protein PhoB
NECFGCCN_03403 3.5e-233 phoR 2.7.13.3 T Histidine kinase
NECFGCCN_03404 7.7e-234 brnQ U Component of the transport system for branched-chain amino acids
NECFGCCN_03405 1.6e-252 proY E Cryptic permease that may be involved in the transport of proline across the inner membrane
NECFGCCN_03406 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 13 family
NECFGCCN_03407 3e-170 K transcriptional regulator
NECFGCCN_03409 2.4e-118 Q Hydrolase
NECFGCCN_03410 1.3e-99 S Antibiotic biosynthesis monooxygenase
NECFGCCN_03411 0.0 nfdA S metal-dependent hydrolase with the TIM-barrel fold
NECFGCCN_03412 4e-156 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NECFGCCN_03413 1.2e-180 rbsK 2.7.1.15 G Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6- deoxy-6-sulfo-D-fructose 1-phosphate (SFP)
NECFGCCN_03414 1.3e-252 ulaA 2.7.1.194 G protein conserved in bacteria
NECFGCCN_03415 8.9e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NECFGCCN_03416 9.1e-72 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NECFGCCN_03417 3.4e-114 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
NECFGCCN_03418 4.6e-108 acpH 3.1.4.14 S Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
NECFGCCN_03419 7.7e-202 queA 2.4.2.29, 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NECFGCCN_03420 3.6e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NECFGCCN_03421 7.8e-52 yajC U Preprotein translocase subunit
NECFGCCN_03422 0.0 secD U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NECFGCCN_03423 3.8e-171 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NECFGCCN_03424 9.8e-64 S glyoxalase bleomycin resistance protein dioxygenase
NECFGCCN_03425 5.9e-118 K transcriptional regulator
NECFGCCN_03426 1.6e-176 tsx M nucleoside-specific channel-forming protein
NECFGCCN_03427 9e-82 yajI M Lipoprotein
NECFGCCN_03428 1.7e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NECFGCCN_03429 9.8e-208 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NECFGCCN_03430 9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NECFGCCN_03431 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NECFGCCN_03432 2.1e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NECFGCCN_03433 4.3e-94 pgpA 3.1.3.27 I Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NECFGCCN_03434 1.3e-182 yajO 1.1.1.91 C Aldo keto reductase
NECFGCCN_03435 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NECFGCCN_03436 1.1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NECFGCCN_03437 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NECFGCCN_03438 6.7e-273 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NECFGCCN_03439 4.2e-83 S Activator of Hsp90 ATPase 1 family protein
NECFGCCN_03440 2.1e-103 thiJ 2.7.11.1, 3.5.1.124 S TIGRFAM DJ-1 family protein
NECFGCCN_03441 3.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NECFGCCN_03442 5.7e-83 yajQ S Belongs to the UPF0234 family
NECFGCCN_03443 7.2e-245 yajR EGP Major facilitator Superfamily
NECFGCCN_03444 1.2e-232 S oxidoreductase
NECFGCCN_03445 1.7e-238 EGP Major facilitator Superfamily
NECFGCCN_03446 1.1e-144 G Xylose isomerase
NECFGCCN_03447 2e-129 C Succinate dehydrogenase fumarate reductase, flavoprotein subunit
NECFGCCN_03448 2.8e-90 yafM L Transposase and inactivated derivatives
NECFGCCN_03449 2.1e-16 Q Methyltransferase domain protein
NECFGCCN_03450 2.7e-39 MA20_06245 S yiaA/B two helix domain
NECFGCCN_03451 1e-310 uup S abc transporter atp-binding protein
NECFGCCN_03452 3.2e-12 ycdA S Domain of unknown function (DUF4352)
NECFGCCN_03453 1.1e-100 ybhL S Belongs to the BI1 family
NECFGCCN_03454 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NECFGCCN_03455 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NECFGCCN_03456 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NECFGCCN_03457 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NECFGCCN_03458 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NECFGCCN_03459 3e-292 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NECFGCCN_03460 4.2e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
NECFGCCN_03461 1.3e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NECFGCCN_03462 4.8e-22
NECFGCCN_03463 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NECFGCCN_03464 1.1e-276 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NECFGCCN_03465 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NECFGCCN_03466 2.2e-38 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NECFGCCN_03467 8.3e-93 ypsA S Belongs to the UPF0398 family
NECFGCCN_03468 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NECFGCCN_03469 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NECFGCCN_03470 1.6e-252 pepC 3.4.22.40 E aminopeptidase
NECFGCCN_03471 2.4e-72 yhaI S Protein of unknown function (DUF805)
NECFGCCN_03472 5e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NECFGCCN_03473 3.7e-271 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NECFGCCN_03474 1.5e-125 macB_2 V FtsX-like permease family
NECFGCCN_03475 1.8e-68 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NECFGCCN_03476 4.3e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NECFGCCN_03477 1.5e-268 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NECFGCCN_03478 5.1e-90 nolA K transcriptional regulator
NECFGCCN_03479 1.2e-201 P Major facilitator superfamily
NECFGCCN_03481 2.7e-139 C Iron-sulfur cluster-binding domain
NECFGCCN_03482 6e-250 3.1.6.1 P Sulfatase
NECFGCCN_03483 2.2e-311 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NECFGCCN_03484 5e-268 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NECFGCCN_03485 5.5e-192 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NECFGCCN_03486 3.4e-27 yfgJ S bacterial-type flagellum-dependent swarming motility
NECFGCCN_03487 5.8e-181 S Protein involved in oxidoreductase activity
NECFGCCN_03488 8.3e-279 der S GTPase that plays an essential role in the late steps of ribosome biogenesis
NECFGCCN_03489 1.7e-173 bamB M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NECFGCCN_03490 7.1e-107 yfgM S protein conserved in bacteria
NECFGCCN_03491 1.5e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NECFGCCN_03492 6e-205 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NECFGCCN_03493 1.1e-130 rodZ S Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis
NECFGCCN_03494 3.3e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NECFGCCN_03495 3.9e-173 GM NmrA-like family
NECFGCCN_03496 2.1e-26 ybiJ S Protein of unknown function (DUF1471)
NECFGCCN_03497 5.6e-158 K AraC-type transcriptional regulator N-terminus
NECFGCCN_03498 1.6e-132 IQ short-chain dehydrogenase
NECFGCCN_03499 6.6e-102 yjgJ K tetR family
NECFGCCN_03500 5.5e-127 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_03501 5.4e-81
NECFGCCN_03502 6.9e-90 tssJ S Type VI secretion
NECFGCCN_03503 1.1e-206 S type VI secretion protein
NECFGCCN_03504 0.0 tssF S Type VI secretion
NECFGCCN_03505 3.9e-298 S type VI secretion-associated protein
NECFGCCN_03506 0.0 N type VI secretion protein
NECFGCCN_03507 1.1e-211
NECFGCCN_03508 1.7e-46 S PAAR motif
NECFGCCN_03509 0.0 S Uncharacterized alpha/beta hydrolase domain (DUF2235)
NECFGCCN_03510 9.1e-76 M Putative cell wall binding repeat
NECFGCCN_03511 1e-47 S dextransucrase activity
NECFGCCN_03512 1e-12 S dextransucrase activity
NECFGCCN_03513 8.3e-171 mprF 2.3.2.3 S Membrane
NECFGCCN_03514 4.7e-243 clsB 2.7.8.8 I Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NECFGCCN_03515 1.5e-146 ybhP L Endonuclease Exonuclease Phosphatase
NECFGCCN_03516 3.8e-70 ybhQ S inner membrane protein YbhQ
NECFGCCN_03517 3.7e-199 ybhR V Transport Permease Protein
NECFGCCN_03518 5e-199 ybhS V ABC-type multidrug transport system, permease component
NECFGCCN_03519 0.0 ybhF V (ABC) transporter
NECFGCCN_03520 6.9e-120 ybhG M Secretion protein
NECFGCCN_03521 5.2e-116 ybiH K Transcriptional regulator
NECFGCCN_03522 4.2e-164 K transcriptional regulator
NECFGCCN_03523 1.1e-248 G Major Facilitator Superfamily
NECFGCCN_03524 2e-127 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_03525 3.9e-52 S dextransucrase activity
NECFGCCN_03526 3.2e-89 abiGI K Transcriptional regulator, AbiEi antitoxin
NECFGCCN_03527 1.5e-192 P periplasmic binding protein
NECFGCCN_03528 3.5e-172 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_03529 4.7e-129 fecE 3.6.3.34 HP (ABC) transporter
NECFGCCN_03530 1.7e-131 5.3.3.7 P Molybdenum ABC transporter, periplasmic molybdate-binding protein
NECFGCCN_03531 9.2e-59 aroE 1.1.1.25, 4.2.1.10 E shikimate
NECFGCCN_03532 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NECFGCCN_03533 1.9e-223 pbuX F xanthine permease
NECFGCCN_03534 1.2e-269 V (ABC) transporter
NECFGCCN_03535 8.9e-83 cobQ S glutamine amidotransferase
NECFGCCN_03536 8e-168 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NECFGCCN_03537 0.0 ynfE 1.8.5.3, 1.97.1.9 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_03538 1.9e-40 ynfD S membrane
NECFGCCN_03539 7.6e-129 ynfC M Uncharacterised protein family (UPF0257)
NECFGCCN_03540 1.3e-102 speG 2.3.1.57 J Catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine
NECFGCCN_03541 2.3e-54 ynfB S Belongs to the UPF0482 family
NECFGCCN_03542 3.1e-53 ynfA S UPF0060 membrane protein
NECFGCCN_03543 3e-232 yjjL G Major facilitator superfamily
NECFGCCN_03544 1.5e-264 mtlK 1.1.1.11, 1.1.1.17, 1.1.1.289, 1.1.1.57, 1.1.1.58, 1.1.1.67, 2.7.1.17 G Belongs to the mannitol dehydrogenase family
NECFGCCN_03545 1.1e-69 uspF T Universal stress protein
NECFGCCN_03546 8.1e-120 ydfH K transcriptional regulator
NECFGCCN_03547 1.8e-136 ydfG 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_03548 0.0 dcp 3.4.15.5, 3.4.24.70 E PFAM peptidase M3A and M3B, thimet oligopeptidase F
NECFGCCN_03549 3.5e-51
NECFGCCN_03550 4.6e-109 K transcriptional regulator
NECFGCCN_03551 5.7e-110 yedK S SOS response associated peptidase (SRAP)
NECFGCCN_03553 7.6e-80 K LuxR family transcriptional regulator
NECFGCCN_03555 2.9e-76 ibp O Belongs to the small heat shock protein (HSP20) family
NECFGCCN_03556 9.5e-81 cinA 3.5.1.42 S Competence-damaged protein
NECFGCCN_03557 8.5e-205 T EAL domain
NECFGCCN_03559 7e-138 ykgA K transcriptional regulator
NECFGCCN_03560 3.4e-226 ygbN EG Gluconate
NECFGCCN_03561 3.2e-144 ygbM 5.3.1.22, 5.3.1.35 G Belongs to the hyi family
NECFGCCN_03562 8.4e-79 pcaF 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
NECFGCCN_03563 6.1e-24 S dextransucrase activity
NECFGCCN_03564 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NECFGCCN_03565 6.2e-100 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NECFGCCN_03566 1.7e-35 S the current gene model (or a revised gene model) may contain a frame shift
NECFGCCN_03568 1.4e-15 S HipA-like C-terminal domain
NECFGCCN_03569 2.9e-33 XK27_00500 L SNF2 family N-terminal domain
NECFGCCN_03571 4.1e-192 murB 1.3.1.98 M cell wall formation
NECFGCCN_03572 5.7e-180 birA 2.7.1.33, 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NECFGCCN_03573 7.7e-174 coaA 2.7.1.33 F pantothenic acid kinase
NECFGCCN_03575 1e-26 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NECFGCCN_03576 9e-101 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NECFGCCN_03577 4.8e-151 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NECFGCCN_03578 5.8e-16 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NECFGCCN_03579 6.8e-190 tcsA S membrane
NECFGCCN_03580 2.9e-24 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NECFGCCN_03581 2.8e-152 K transcriptional regulator
NECFGCCN_03582 4.3e-155 S COG0491 Zn-dependent hydrolases, including glyoxylases
NECFGCCN_03583 4.1e-18 rpsV J 30S ribosomal protein subunit S22 family
NECFGCCN_03584 0.0 maeA 1.1.1.38 C Malic enzyme
NECFGCCN_03586 0.0 tlrC S ABC transporter
NECFGCCN_03587 1.3e-171 K Transcriptional regulator
NECFGCCN_03588 7.1e-104 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NECFGCCN_03589 4.2e-189 adhP 1.1.1.1 S alcohol dehydrogenase
NECFGCCN_03590 0.0 E Extracellular solute-binding protein
NECFGCCN_03591 2.7e-150 P PFAM binding-protein-dependent transport systems inner membrane component
NECFGCCN_03592 2.8e-130 P COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components
NECFGCCN_03593 2.3e-282 P ATPase activity
NECFGCCN_03594 1.6e-185 MA20_00170 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECFGCCN_03595 1.4e-195 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NECFGCCN_03596 4.9e-202 araJ EGP Major facilitator Superfamily
NECFGCCN_03597 3.7e-73 E Lactoylglutathione lyase and related lyases
NECFGCCN_03598 2.3e-153 ppk2 2.7.4.1 H polyphosphate kinase
NECFGCCN_03599 7.8e-25
NECFGCCN_03600 2.6e-55 S CcdB protein
NECFGCCN_03601 5.4e-121 fdnI C formate dehydrogenase
NECFGCCN_03602 5.7e-174 fdnH C formate dehydrogenase
NECFGCCN_03603 2.6e-202 fdnG 1.17.1.9, 1.17.5.3 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_03604 1.1e-141
NECFGCCN_03605 3.1e-26
NECFGCCN_03606 1e-48 S Phage-related protein
NECFGCCN_03607 1.2e-43 K sequence-specific DNA binding
NECFGCCN_03608 7.6e-21 S the current gene model (or a revised gene model) may contain a frame shift
NECFGCCN_03609 5.6e-32 ybfA S Membrane
NECFGCCN_03610 1.1e-303 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NECFGCCN_03611 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NECFGCCN_03612 4.9e-94 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NECFGCCN_03613 0.0 T PhoQ Sensor
NECFGCCN_03614 1.2e-123 K response regulator
NECFGCCN_03615 6.2e-73
NECFGCCN_03616 0.0 pgm 5.4.2.2 G Phosphoglucomutase
NECFGCCN_03617 1.1e-100 seqA L Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NECFGCCN_03618 4.1e-104 ybfF S Alpha beta hydrolase
NECFGCCN_03619 5e-42 ybfE S CopG domain protein DNA-binding domain protein
NECFGCCN_03620 1.5e-100 fldA C Low-potential electron donor to a number of redox enzymes
NECFGCCN_03621 4e-83 fur K belongs to the Fur family
NECFGCCN_03622 1.2e-70 citA EGP Is involved in the uptake of citrate and the transport of protons into the cell
NECFGCCN_03623 4.2e-53 ybfN S YbfN-like lipoprotein
NECFGCCN_03624 2.4e-280 chiP S Outer membrane porin
NECFGCCN_03626 0.0 glnS 6.1.1.18 J Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NECFGCCN_03627 7.4e-71 nagE 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Phosphotransferase System
NECFGCCN_03628 3.2e-109 fdoG 1.17.1.9, 1.17.5.3 C Sulfate ABC transporter substrate-binding protein
NECFGCCN_03629 4.4e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NECFGCCN_03630 3.8e-15 S Protein of unknown function (DUF1471)
NECFGCCN_03631 5.3e-181 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NECFGCCN_03632 2.2e-48 ptxB 2.7.1.194, 2.7.1.200 G Phosphotransferase system, lactose cellobiose-specific IIB subunit
NECFGCCN_03633 1.7e-246 ulaA 2.7.1.194 G protein conserved in bacteria
NECFGCCN_03634 8.4e-151 4.1.2.13 G Aldolase
NECFGCCN_03635 7.3e-40
NECFGCCN_03636 7.3e-74 ulaC 2.7.1.194, 2.7.1.200, 2.7.1.202 G PTS IIA-like nitrogen-regulatory protein PtsN
NECFGCCN_03637 3.2e-104 adk 2.7.4.3 F adenylate kinase activity
NECFGCCN_03638 6.3e-46 S Branched-chain amino acid transport
NECFGCCN_03639 4.8e-112 azlC E branched-chain amino acid
NECFGCCN_03640 7.7e-97 sinR K Transcriptional regulator
NECFGCCN_03641 3.6e-185 aglR K PFAM Periplasmic binding protein LacI transcriptional regulator
NECFGCCN_03642 9.8e-65 thiT S Thiamine transporter
NECFGCCN_03643 9.4e-133 vncS 2.7.13.3 T Histidine kinase
NECFGCCN_03644 3.4e-49 3.6.1.55 F NUDIX domain
NECFGCCN_03646 1.5e-23 csrA J Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NECFGCCN_03647 5.5e-12
NECFGCCN_03648 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NECFGCCN_03649 5.6e-86 recX 2.4.1.337 GT4 S Regulatory protein recX
NECFGCCN_03650 1.6e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NECFGCCN_03651 4.9e-82 ygaD 3.5.1.42 J Belongs to the CinA family
NECFGCCN_03652 4.5e-155 mntA 3.2.1.78 GH26 P Belongs to the bacterial solute-binding protein 9 family
NECFGCCN_03653 3.9e-143 znuB P ABC-type Mn2 Zn2 transport systems permease components
NECFGCCN_03654 4.4e-118 znuC P (ABC) transporter
NECFGCCN_03656 1.3e-159 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NECFGCCN_03657 1.3e-31 yaaA S Ribosome-associated protein
NECFGCCN_03658 3.9e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NECFGCCN_03659 1.4e-89 ppiB 2.7.11.1, 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NECFGCCN_03660 8.5e-136 lpxH 3.6.1.54 S Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NECFGCCN_03661 1.1e-45
NECFGCCN_03662 2e-86 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NECFGCCN_03663 2.4e-203 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NECFGCCN_03664 2.2e-204 selU H Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NECFGCCN_03665 7.8e-32 D Antitoxin component of a toxin-antitoxin (TA) module
NECFGCCN_03666 1.2e-61 doc S Death ON curing protein
NECFGCCN_03667 2.2e-58 L Helix-turn-helix domain
NECFGCCN_03668 2.4e-136 IQ Acetoin reductase
NECFGCCN_03670 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NECFGCCN_03672 0.0 S Domain of unknown function (DUF5107)
NECFGCCN_03673 1.3e-221 yphH 2.7.1.2 GK ROK family
NECFGCCN_03674 6.4e-68 yphA S SURF4 family
NECFGCCN_03675 4.2e-239 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NECFGCCN_03676 1.6e-227 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NECFGCCN_03677 2e-55 glnB K Belongs to the P(II) protein family
NECFGCCN_03678 5.8e-247 yfhA T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
NECFGCCN_03679 7.9e-123 yfhG NU YfhG lipoprotein
NECFGCCN_03680 9e-246 T PhoQ Sensor
NECFGCCN_03681 0.0 purL 6.3.5.3 F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
NECFGCCN_03682 1.3e-306 mltF M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella
NECFGCCN_03683 1.1e-89 tadA 3.4.17.13, 3.5.4.1, 3.5.4.3, 3.5.4.33, 3.8.1.5 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NECFGCCN_03684 1.5e-115 yfhB 3.1.3.27 E HAD superfamily (Subfamily IF) hydrolase, YfhB
NECFGCCN_03685 3.5e-149 yfhH K Transcriptional regulator
NECFGCCN_03686 4.6e-47 yfhL C Ferredoxin
NECFGCCN_03687 1.3e-63 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NECFGCCN_03688 4.6e-129 pdxJ 2.6.99.2 H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NECFGCCN_03689 2.7e-137 recO 2.6.99.2 L Involved in DNA repair and RecF pathway recombination
NECFGCCN_03690 1.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NECFGCCN_03691 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NECFGCCN_03692 1.5e-188 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NECFGCCN_03693 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NECFGCCN_03695 7.5e-80 rseC T Positive regulator of
NECFGCCN_03696 1.4e-173 rseB T Negative regulator of sigma E activity
NECFGCCN_03697 5.9e-104 rseA T An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NECFGCCN_03698 4.2e-101 rpoE K Belongs to the sigma-70 factor family. ECF subfamily
NECFGCCN_03699 0.0 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NECFGCCN_03700 1.8e-133 yfiC 2.1.1.223, 2.1.1.72 J Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NECFGCCN_03701 1.1e-224 srmB 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity
NECFGCCN_03702 6.4e-66 grcA 1.14.13.236 S Acts as a radical domain for damaged PFL and possibly other radical proteins
NECFGCCN_03703 4.5e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NECFGCCN_03704 8.4e-188 yfiF 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NECFGCCN_03705 1.3e-78 trxC 1.8.1.8 O Thioredoxin
NECFGCCN_03706 1.2e-123 yfiP S DTW domain containing protein
NECFGCCN_03707 0.0 yfiQ 6.2.1.13 C Acyl-CoA synthetase (NDP forming)
NECFGCCN_03708 1.3e-262 pssA 2.7.8.8 I Catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine
NECFGCCN_03709 6.2e-54 yfiM S Required for high salt suppression of motility
NECFGCCN_03710 7.6e-236 kgtP EGP transporter
NECFGCCN_03711 3.6e-26 lctO C Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain
NECFGCCN_03712 2.5e-78 Q Escherichia coli O157 H7 ortholog z1925
NECFGCCN_03713 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NECFGCCN_03714 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NECFGCCN_03715 5.7e-201 V permease protein
NECFGCCN_03716 7.5e-121 macB V ABC transporter, ATP-binding protein
NECFGCCN_03717 2.6e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_03718 7.6e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
NECFGCCN_03719 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NECFGCCN_03720 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NECFGCCN_03721 1.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NECFGCCN_03722 1.8e-221 pyrP F uracil Permease
NECFGCCN_03724 1.8e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NECFGCCN_03725 9.1e-16 2.4.1.21 GT5 M Right handed beta helix region
NECFGCCN_03726 2.9e-174 spd F DNA RNA non-specific endonuclease
NECFGCCN_03727 7.7e-92 lemA S LemA family
NECFGCCN_03728 4e-135 htpX O Belongs to the peptidase M48B family
NECFGCCN_03729 1.7e-119 sirR K iron dependent repressor
NECFGCCN_03730 2.1e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
NECFGCCN_03731 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
NECFGCCN_03732 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
NECFGCCN_03733 9.8e-56 S Psort location CytoplasmicMembrane, score
NECFGCCN_03734 1.8e-63 S Domain of unknown function (DUF4430)
NECFGCCN_03736 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NECFGCCN_03737 1.2e-85 ybeY 2.6.99.2, 3.5.4.5 J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NECFGCCN_03738 1.3e-168 corC P Mg2 and Co2 transporter CorC
NECFGCCN_03739 2.7e-280 lnt GT2 M Transfers the fatty acyl group on membrane lipoproteins
NECFGCCN_03740 3.6e-196 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NECFGCCN_03741 1.1e-127 pnuC H nicotinamide mononucleotide transporter
NECFGCCN_03742 2.1e-166 zitB P cation diffusion facilitator family transporter
NECFGCCN_03743 5.6e-35 ybgS S YbgS-like protein
NECFGCCN_03744 1.9e-200 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NECFGCCN_03745 2e-143 gpmA 5.4.2.11 G Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily
NECFGCCN_03746 5.4e-200 galM 2.7.1.6, 5.1.3.3 G converts alpha-aldose to the beta-anomer
NECFGCCN_03747 7.8e-216 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NECFGCCN_03748 5.4e-208 galT 2.7.7.12 H galactose-1-phosphate uridylyltransferase
NECFGCCN_03749 1.3e-198 galE 5.1.3.2 M udp-glucose 4-epimerase
NECFGCCN_03750 4.8e-279 modF 3.6.3.21, 3.6.3.34 P ABC-type molybdenum transport system ATPase component photorepair protein PhrA
NECFGCCN_03751 2.6e-138 modE H Transcriptional regulator
NECFGCCN_03752 1.4e-16 acrZ U drug transmembrane transporter activity
NECFGCCN_03753 6.3e-137 modA 5.3.3.7 P ABC transporter, periplasmic molybdate-binding protein
NECFGCCN_03754 4.1e-119 modB 3.6.3.29 P ABC-type molybdate transport system, permease component
NECFGCCN_03755 1.1e-189 modC 3.6.3.29 P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NECFGCCN_03756 6e-146 ybhA S hydrolases of the HAD superfamily
NECFGCCN_03757 4e-192 pgl 3.1.1.31 G Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
NECFGCCN_03758 1.9e-38 ariR S Two-component-system connector protein AriR
NECFGCCN_03759 8.3e-40
NECFGCCN_03760 8.1e-38 ycgZ S Two-component-system connector protein YcgZ
NECFGCCN_03761 9e-223 ycgF T EAL domain
NECFGCCN_03762 3.5e-137 ycgE K Transcriptional regulator
NECFGCCN_03763 4e-101 K helix_turn_helix, Lux Regulon
NECFGCCN_03764 6e-29
NECFGCCN_03765 1.9e-89
NECFGCCN_03766 8.3e-171 S enterobacterial common antigen metabolic process
NECFGCCN_03767 0.0 czcA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_03768 2.7e-186 ttgA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_03770 1.8e-69 uspF T Required for resistance to DNA-damaging agents
NECFGCCN_03771 1e-61 ctpF P ATPase, P-type (transporting), HAD superfamily, subfamily IC
NECFGCCN_03772 1.8e-275 yjiR K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_03773 9.3e-22 yjiS S Domain of unknown function (DUF1127)
NECFGCCN_03774 6.8e-78 slyA K Transcriptional regulator
NECFGCCN_03775 2.3e-193 yiaV V Secretion Protein
NECFGCCN_03776 6.3e-188 S Protein of unknown function (DUF2955)
NECFGCCN_03777 3.2e-29 S Protein of unknown function (DUF3343)
NECFGCCN_03778 2e-135 yjiL I 4 iron, 4 sulfur cluster binding
NECFGCCN_03779 7.5e-219 yjiM E cellular response to DNA damage stimulus
NECFGCCN_03780 1.8e-34 S Uncharacterized conserved protein (DUF2164)
NECFGCCN_03781 3.5e-222 mdtM EGP Major facilitator Superfamily
NECFGCCN_03782 5.3e-229 yjiN S Membrane
NECFGCCN_03783 2.8e-109 rhtC E PFAM Lysine exporter protein (LYSE YGGA)
NECFGCCN_03784 3.4e-149 msmR K transcriptional regulator
NECFGCCN_03785 1.1e-151 yfaD S Transposase
NECFGCCN_03786 1.2e-255 gabD 1.2.1.16, 1.2.1.20, 1.2.1.24, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
NECFGCCN_03787 9.1e-98 S YfaZ precursor
NECFGCCN_03788 7.5e-180 yjiA S cobalamin synthesis protein
NECFGCCN_03789 7.7e-34 yjiX S Selenoprotein, putative
NECFGCCN_03790 3.4e-194 cstA T Carbon starvation protein
NECFGCCN_03791 2.3e-13
NECFGCCN_03792 9.5e-283 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NECFGCCN_03793 2.9e-224 ynfM EGP Major facilitator Superfamily
NECFGCCN_03794 1.9e-161 ynfL K transcriptional regulator
NECFGCCN_03795 9.7e-225 mlc GK Mlc, controls the expression of genes involved in the phosphotransferase and phosphoenolpyruvate systems, regulates genes involved in the uptake of sugars
NECFGCCN_03796 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NECFGCCN_03797 6e-225 clcB P Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response
NECFGCCN_03798 1.8e-107 dmsD S Required for biogenesis assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein
NECFGCCN_03799 2.7e-141 dmsC S Dimethyl sulfoxide reductase
NECFGCCN_03800 4.8e-31 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NECFGCCN_03802 2.5e-78 S dextransucrase activity
NECFGCCN_03803 2.8e-19 S dextransucrase activity
NECFGCCN_03804 1.1e-20 S dextransucrase activity
NECFGCCN_03805 5.2e-121 xylH G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_03806 1.4e-225 xylR 5.3.1.12 K transcriptional regulator
NECFGCCN_03807 1.3e-102 bax GH73 S FlgJ-related protein
NECFGCCN_03808 0.0 malS 3.2.1.1 GH13 G alpha-amylase
NECFGCCN_03809 9.9e-249 avtA 2.6.1.66 E Valine--pyruvate aminotransferase
NECFGCCN_03810 4.4e-88 ysaA C electron transport
NECFGCCN_03811 9.4e-155 yiaJ K transcriptional regulator
NECFGCCN_03812 9.2e-189 dlgD 1.1.1.130, 1.5.1.21 C Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate
NECFGCCN_03813 2.4e-83 yiaL G Domain of unknown function (DUF386)
NECFGCCN_03814 4e-170 L Domain of unknown function (DUF4862)
NECFGCCN_03815 3.2e-242 G Major facilitator superfamily
NECFGCCN_03816 2.8e-290 lyx 2.7.1.17, 2.7.1.189, 2.7.1.5, 2.7.1.51, 2.7.1.53 G Belongs to the FGGY kinase family
NECFGCCN_03817 1.9e-118 sgbH 4.1.1.85, 4.1.2.43 G decarboxylase
NECFGCCN_03818 2.2e-162 sgbU 5.1.3.22 G 3-epimerase
NECFGCCN_03819 1.6e-131 araD 4.1.1.104, 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 G Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate
NECFGCCN_03820 0.0 selB J Translation elongation factor
NECFGCCN_03821 7.1e-240 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
NECFGCCN_03822 5.4e-107 yibF 2.5.1.18 O Glutathione S-Transferase
NECFGCCN_03823 0.0 mtlA 2.7.1.197, 2.7.1.202 G PTS system mannitol-specific
NECFGCCN_03824 2.9e-210 mtlD 1.1.1.17 C Mannitol-1-Phosphate 5-Dehydrogenase
NECFGCCN_03825 1.3e-102 mtlR K Mannitol repressor
NECFGCCN_03826 5.9e-35 yibT S response to butan-1-ol
NECFGCCN_03827 2.7e-53 yibL S Protein of unknown function (DUF2810)
NECFGCCN_03828 8.4e-288 lldP C L-lactate permease
NECFGCCN_03829 1.2e-135 lldR K Represses the lctPRD operon
NECFGCCN_03830 1.9e-225 lldD 1.1.2.3 C Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain
NECFGCCN_03831 1.8e-86 trmL 2.1.1.207 J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NECFGCCN_03832 2.5e-152 cysE 2.3.1.30 E serine acetyltransferase
NECFGCCN_03833 5.1e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NECFGCCN_03834 2.4e-83 secB U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NECFGCCN_03835 3.3e-42 grxC O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NECFGCCN_03836 8e-73 yibN 2.8.1.1, 2.8.1.2 P rhodanese-related sulfurtransferase
NECFGCCN_03837 5.6e-294 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NECFGCCN_03838 9.3e-138 envC D peptidase
NECFGCCN_03839 2.1e-166 yibQ S protein conserved in bacteria
NECFGCCN_03840 5.1e-150 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NECFGCCN_03841 2e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NECFGCCN_03842 2.8e-224 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NECFGCCN_03843 3.3e-180 hldD 5.1.3.20 GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose
NECFGCCN_03844 2.8e-204 rfaF GT9 M heptosyltransferase
NECFGCCN_03845 1.9e-178 rfaC GT9 M lipopolysaccharide heptosyltransferase I
NECFGCCN_03846 1.1e-172 rfaZ GT73 S lipopolysaccharide core region biosynthetic process
NECFGCCN_03847 1.8e-212 M O-Antigen ligase
NECFGCCN_03848 6.9e-198 waaU M Glycosyltransferase family 9 (heptosyltransferase)
NECFGCCN_03849 6.6e-192 walW G Lipopolysaccharide biosynthesis protein
NECFGCCN_03850 3.3e-141 livG E Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids
NECFGCCN_03851 2.6e-186 livM E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_03852 6.8e-151 livH E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_03853 1e-207 livK E With LivFGHM is involved in the high affinity leucine transport
NECFGCCN_03854 9.5e-141 eutC 4.3.1.7 E Belongs to the EutC family
NECFGCCN_03855 1.7e-262 eutB 4.3.1.7 E With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine
NECFGCCN_03856 1.1e-248 eat E amino acid
NECFGCCN_03857 5.5e-264 mmuP E amino acid
NECFGCCN_03858 8.1e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NECFGCCN_03859 3.6e-174 tauA P taurine ABC transporter
NECFGCCN_03860 1.9e-138 tauB 3.6.3.36 P Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NECFGCCN_03861 6.5e-132 tauC P ABC-type nitrate sulfonate bicarbonate transport system permease component
NECFGCCN_03862 1.4e-166 tauD 1.14.11.17 Q taurine catabolism dioxygenase
NECFGCCN_03863 0.0 I Acyltransferase
NECFGCCN_03864 8.6e-63 fepB P Periplasmic binding protein
NECFGCCN_03865 1.8e-72 fepB P Periplasmic binding protein
NECFGCCN_03866 3.3e-214 entC 5.4.4.2 HQ Isochorismate synthase
NECFGCCN_03867 1.1e-308 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NECFGCCN_03868 2e-160 entB 3.3.2.1, 6.3.2.14 Q Phosphopantetheine attachment site
NECFGCCN_03869 2.1e-129 IQ PFAM Short-chain dehydrogenase reductase SDR
NECFGCCN_03870 2.9e-72 entH 3.1.2.28 Q Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules
NECFGCCN_03871 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_03872 3.1e-90 yceD K metal-binding, possibly nucleic acid-binding protein
NECFGCCN_03873 5.5e-127 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NECFGCCN_03874 9.8e-234 P COG0168 Trk-type K transport systems, membrane components
NECFGCCN_03875 4.8e-117 ktrA P COG0569 K transport systems, NAD-binding component
NECFGCCN_03876 3.2e-147 cbiQ P cobalt transport
NECFGCCN_03877 8.7e-309 ykoD P abc transporter atp-binding protein
NECFGCCN_03878 2.3e-93 S UPF0397 protein
NECFGCCN_03879 6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NECFGCCN_03880 1.3e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NECFGCCN_03881 1.2e-99 metI P ABC transporter (Permease
NECFGCCN_03882 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NECFGCCN_03883 2.3e-262 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NECFGCCN_03884 1.9e-164 metQ M Belongs to the NlpA lipoprotein family
NECFGCCN_03885 6.3e-138 ET ABC transporter substrate-binding protein
NECFGCCN_03886 2.6e-80 fasA KT Response regulator of the LytR AlgR family
NECFGCCN_03887 2.2e-23 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NECFGCCN_03888 1.4e-19
NECFGCCN_03890 1.4e-162 repB K Belongs to the ParB family
NECFGCCN_03891 3.1e-228 parA D COG1192 ATPases involved in chromosome partitioning
NECFGCCN_03892 9e-184 repA S RePlication protein
NECFGCCN_03893 1.9e-138 L Phage integrase family
NECFGCCN_03894 3.8e-08
NECFGCCN_03896 8e-114 pscB M CHAP domain protein
NECFGCCN_03897 2.5e-191 glnA 6.3.1.2 E glutamine synthetase
NECFGCCN_03898 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NECFGCCN_03899 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NECFGCCN_03900 4.7e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NECFGCCN_03901 7.7e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NECFGCCN_03902 3.3e-12 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NECFGCCN_03903 0.0 fdhF 1.17.1.10, 1.17.1.9, 1.17.99.7 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_03904 4.4e-76 fdhF 1.17.1.10, 1.17.1.9, 1.17.99.7 C Spermidine putrescine ABC transporter substrate-binding protein
NECFGCCN_03905 3.7e-123 K response regulator
NECFGCCN_03906 3.1e-136 K Transcriptional regulator, AbiEi antitoxin N-terminal domain
NECFGCCN_03907 2e-166 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NECFGCCN_03908 1.5e-186 2.7.1.15, 2.7.1.4 G PfkB domain protein
NECFGCCN_03909 1.7e-168 rbsB G PFAM Periplasmic binding protein LacI transcriptional regulator
NECFGCCN_03910 1.8e-168 MA20_14255 P Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_03911 9.4e-278 rbsA 3.6.3.17 P import. Responsible for energy coupling to the transport system
NECFGCCN_03912 0.0 virA T Histidine kinase
NECFGCCN_03913 8.2e-18
NECFGCCN_03914 2.3e-147 phnP 3.1.4.55 S Carbon-phosphorus lyase complex accessory protein
NECFGCCN_03915 1.7e-99 phnN 2.7.4.23 F Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
NECFGCCN_03916 5.9e-208 phnM 3.6.1.63 P phosphonate metabolism protein PhnM
NECFGCCN_03917 6e-123 phnL 2.7.8.37 P phosphonate C-P lyase system protein PhnL
NECFGCCN_03918 1.9e-138 phnK 4.7.1.1 P phosphonate C-P lyase system protein PhnK
NECFGCCN_03919 5.1e-164 phnJ 4.7.1.1 H Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose
NECFGCCN_03920 1.7e-196 phnI 2.7.8.37 P Phosphonate
NECFGCCN_03921 1.5e-101 phnH 2.7.8.37 P phosphonate C-P lyase system protein PhnH
NECFGCCN_03922 1.1e-77 phnG 2.7.8.37 P Phosphonate C-P lyase system protein PhnG
NECFGCCN_03923 4.5e-129 phnF K Transcriptional regulator
NECFGCCN_03924 5.2e-80 phnB S PFAM Glyoxalase bleomycin resistance protein dioxygenase
NECFGCCN_03925 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
NECFGCCN_03926 1.1e-270 proP EGP transporter
NECFGCCN_03927 1.3e-176 melR 2.1.1.63, 3.1.31.1, 3.2.2.21 K melibiose operon regulatory protein
NECFGCCN_03928 4.8e-265 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides
NECFGCCN_03929 7.2e-256 melB G COG2211 Na melibiose symporter and related transporters
NECFGCCN_03931 2.7e-177 O PFAM StbA family protein
NECFGCCN_03932 1.3e-42 S Plasmid stability protein
NECFGCCN_03933 2.7e-57 S overlaps another CDS with the same product name
NECFGCCN_03934 3.7e-235 L viral genome integration into host DNA
NECFGCCN_03935 7.3e-256
NECFGCCN_03936 2.4e-202
NECFGCCN_03937 1.1e-60 K Peptidase S24-like
NECFGCCN_03938 4.2e-08 L Transposase
NECFGCCN_03939 3.5e-160 3.1.21.3 V type I restriction modification DNA specificity domain
NECFGCCN_03940 6.1e-137 MA20_32445 O PFAM 20S proteasome, A and B subunits
NECFGCCN_03941 4.6e-154 MA20_32430 E Transglutaminase
NECFGCCN_03942 5.2e-170 MA20_32425 S protein conserved in bacteria
NECFGCCN_03943 5.2e-286 gcs2 S Circularly permuted ATP-grasp type 2
NECFGCCN_03944 0.0 treA 3.2.1.28 GH37 G Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NECFGCCN_03945 1.6e-148 foxA P Receptor
NECFGCCN_03946 9.5e-46 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NECFGCCN_03947 0.0 fruA 2.7.1.202 G phosphotransferase system
NECFGCCN_03948 9e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NECFGCCN_03949 1e-224 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NECFGCCN_03951 5.4e-209 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NECFGCCN_03952 2.2e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NECFGCCN_03953 5.3e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NECFGCCN_03954 4.1e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NECFGCCN_03955 2.4e-90 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NECFGCCN_03956 1.4e-33 ypeB 2.7.7.7 S protein conserved in bacteria
NECFGCCN_03957 1.1e-176 yfeH S Bile acid sodium symporter
NECFGCCN_03958 9.2e-167 yfeR K transcriptional regulator
NECFGCCN_03959 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
NECFGCCN_03960 4.4e-255 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NECFGCCN_03961 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NECFGCCN_03963 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NECFGCCN_03964 6e-91 yacP S RNA-binding protein containing a PIN domain
NECFGCCN_03965 5e-282 yciQ S Predicted membrane protein (DUF2207)
NECFGCCN_03966 1.1e-82 lemA S LemA family
NECFGCCN_03967 7.1e-65 panZ K Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion
NECFGCCN_03968 1.3e-208 livK E With LivFGHM is involved in the high affinity leucine transport
NECFGCCN_03969 2.6e-145 livH E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_03970 1.2e-214 livM E Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_03971 7.9e-140 livG E Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids
NECFGCCN_03972 9.3e-127 livF P Branched-chain amino acid transport
NECFGCCN_03973 7.9e-90
NECFGCCN_03974 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NECFGCCN_03975 2.4e-45 ftsL D cell division protein FtsL
NECFGCCN_03976 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NECFGCCN_03977 4.5e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NECFGCCN_03978 1.1e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NECFGCCN_03979 1e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NECFGCCN_03980 5.7e-63 yutD J protein conserved in bacteria
NECFGCCN_03981 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NECFGCCN_03982 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
NECFGCCN_03984 0.0 mdlA V abc transporter atp-binding protein
NECFGCCN_03985 0.0 mdlB V abc transporter atp-binding protein
NECFGCCN_03992 5.9e-43 spiA K sequence-specific DNA binding
NECFGCCN_03994 3.9e-07
NECFGCCN_03995 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NECFGCCN_03996 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NECFGCCN_03997 1.5e-94 V CAAX protease self-immunity
NECFGCCN_03998 4.7e-137 cppA E CppA N-terminal
NECFGCCN_03999 1.1e-170 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NECFGCCN_04000 1.9e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NECFGCCN_04001 7.8e-305 S Bacterial membrane protein, YfhO
NECFGCCN_04002 9.3e-63 isaA GH23 M Immunodominant staphylococcal antigen A
NECFGCCN_04003 2.5e-61 lytE M LysM domain protein
NECFGCCN_04004 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NECFGCCN_04005 1.4e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NECFGCCN_04006 2.7e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NECFGCCN_04007 5.9e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NECFGCCN_04008 9.2e-129 S sequence-specific DNA binding
NECFGCCN_04009 4.3e-231 ymfH S Peptidase M16
NECFGCCN_04010 4.3e-228 ymfF S Peptidase M16
NECFGCCN_04011 1.9e-57 yaaA S S4 domain protein YaaA
NECFGCCN_04012 4.8e-199 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NECFGCCN_04013 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NECFGCCN_04014 2.5e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NECFGCCN_04015 7.1e-153 yvjA S membrane
NECFGCCN_04016 1.1e-305 ybiT S abc transporter atp-binding protein
NECFGCCN_04017 0.0 XK27_10405 S Bacterial membrane protein YfhO
NECFGCCN_04018 2.9e-147
NECFGCCN_04019 1.2e-104 L NgoPII restriction endonuclease
NECFGCCN_04020 1e-20 XK27_10050 K Peptidase S24-like
NECFGCCN_04021 2.1e-94 ispZ D probably involved in intracellular septation
NECFGCCN_04022 2.4e-117 yciC S UPF0259 membrane protein
NECFGCCN_04023 9.7e-76 ykgJ S Fe-S-cluster oxidoreductase
NECFGCCN_04024 1.1e-118 ompW M outer membrane protein W
NECFGCCN_04025 5.7e-126 ybiX S PkhD-type hydroxylase
NECFGCCN_04026 0.0 fiu P receptor
NECFGCCN_04027 7.9e-94 IQ short-chain dehydrogenase
NECFGCCN_04029 3.7e-163 1.6.5.5 C alcohol dehydrogenase
NECFGCCN_04030 2.7e-77 K Transcriptional
NECFGCCN_04031 2.4e-147 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NECFGCCN_04032 4.8e-148 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NECFGCCN_04033 6.8e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_04034 7.2e-59 srlB 2.7.1.198 G PTS system glucitol sorbitol-specific
NECFGCCN_04035 1.2e-151 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific
NECFGCCN_04036 1.4e-101 srlA G PTS system glucitol sorbitol-specific
NECFGCCN_04037 6e-210 mltB GH103 M Lytic murein transglycosylase
NECFGCCN_04038 2.3e-53 S Cupin 2, conserved barrel domain protein
NECFGCCN_04039 9.6e-45 IV02_09080 S conserved protein
NECFGCCN_04040 4.7e-196 efe C Belongs to the iron ascorbate-dependent oxidoreductase family
NECFGCCN_04041 8.6e-145 metQ M Belongs to the nlpA lipoprotein family
NECFGCCN_04042 1.3e-121 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NECFGCCN_04043 1.1e-31 metI P ABC-type metal ion transport system permease component
NECFGCCN_04044 9.4e-231 ygbK 2.7.1.217 S Putative nucleotide-binding of sugar-metabolising enzyme
NECFGCCN_04045 1.2e-73 ygbJ 1.1.1.411 I Dehydrogenase
NECFGCCN_04046 4.5e-70 ygbJ 1.1.1.411 I Dehydrogenase
NECFGCCN_04047 2.4e-133 lacR K DeoR C terminal sensor domain
NECFGCCN_04048 4e-37 penP 3.5.2.6 V Beta-lactamase
NECFGCCN_04049 3.4e-97 hemG 1.3.5.3 CH Protoporphyrinogen oxidase
NECFGCCN_04050 1.3e-271 trkH P Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NECFGCCN_04051 4.3e-104 yigZ 2.1.1.45, 3.4.13.9 S YigZ family
NECFGCCN_04052 2e-263 pepQ 3.4.11.9, 3.4.13.9 E Splits dipeptides with a prolyl residue in the C- terminal position
NECFGCCN_04053 0.0 fadB 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate
NECFGCCN_04054 2.1e-213 fadA 2.3.1.16 I Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed
NECFGCCN_04055 2.8e-128 fre 1.16.1.3, 1.17.1.1, 1.5.1.41 C PFAM Oxidoreductase FAD NAD(P)-binding
NECFGCCN_04056 1.7e-292 ubiD 4.1.1.61, 4.1.1.98 H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis
NECFGCCN_04057 8.4e-87 rfaH K Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho- dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains
NECFGCCN_04058 3.5e-143 tatD L 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair
NECFGCCN_04059 8.6e-134 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides
NECFGCCN_04060 1.1e-66 tatB U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation
NECFGCCN_04061 1.7e-30 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NECFGCCN_04062 0.0 ubiB S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NECFGCCN_04063 2.5e-104 yigP S protein conserved in bacteria
NECFGCCN_04064 1.3e-139 ubiE 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)
NECFGCCN_04065 1.6e-255 rmuC V DNA Recombination protein RmuC
NECFGCCN_04066 6.2e-137 udp 2.4.2.3 F Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NECFGCCN_04067 1.1e-155 ysgA 3.1.1.45 Q Dienelactone hydrolase
NECFGCCN_04068 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NECFGCCN_04069 7.4e-180 metR K transcriptional regulator
NECFGCCN_04070 7e-164 yigM EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NECFGCCN_04071 2e-154 yigL S Hydrolase
NECFGCCN_04072 2.8e-198 pldB 3.1.1.5 I Lysophospholipase
NECFGCCN_04073 3e-105 rhtB E efflux protein
NECFGCCN_04074 2.2e-152 S Transposase
NECFGCCN_04075 1.9e-107 rhtC E threonine efflux protein
NECFGCCN_04076 8.7e-133 recQ 3.6.4.12 L DNA helicase
NECFGCCN_04077 1.4e-08 S dextransucrase activity
NECFGCCN_04078 2.1e-186 S dextransucrase activity
NECFGCCN_04079 2.1e-38 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NECFGCCN_04080 2.3e-81 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NECFGCCN_04081 4.1e-107 pgm G Belongs to the phosphoglycerate mutase family
NECFGCCN_04082 5.4e-107 G Belongs to the phosphoglycerate mutase family
NECFGCCN_04083 2.8e-108 G Belongs to the phosphoglycerate mutase family
NECFGCCN_04084 1.3e-24 I phospholipase d transphosphatidylase
NECFGCCN_04085 6.6e-168 coiA 3.6.4.12 S Competence protein
NECFGCCN_04086 8.1e-274 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NECFGCCN_04087 1.2e-103 S CAAX amino terminal protease family protein
NECFGCCN_04089 7.8e-25 WQ51_00785
NECFGCCN_04090 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NECFGCCN_04091 9.9e-48 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
NECFGCCN_04092 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
NECFGCCN_04093 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
NECFGCCN_04094 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NECFGCCN_04095 2.1e-168 murB 1.3.1.98 M cell wall formation
NECFGCCN_04096 6.4e-81 hycA E seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon
NECFGCCN_04097 2.6e-58 hypA S Probably plays a role in a hydrogenase nickel cofactor insertion step
NECFGCCN_04098 2.8e-165 hypB KO Hydrogenase accessory protein HypB
NECFGCCN_04099 1.9e-43 hypC O Hydrogenase assembly chaperone hypC hupF
NECFGCCN_04100 7.6e-216 hypD O Belongs to the HypD family
NECFGCCN_04101 2.8e-185 hypE O hydrogenase expression formation protein HypE
NECFGCCN_04102 0.0 gltD 1.4.1.13, 1.4.1.14 C Glutamate synthase
NECFGCCN_04103 9.6e-109 nudK 3.6.1.13 L GDP-mannose pyrophosphatase
NECFGCCN_04104 8.7e-198 ypfG S Protein of unknown function (DUF1176)
NECFGCCN_04105 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NECFGCCN_04106 1.1e-175 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NECFGCCN_04107 0.0 maeB 1.1.1.38, 1.1.1.40, 2.3.1.8 C Malic enzyme
NECFGCCN_04108 2.9e-54 eutS E ethanolamine utilization protein
NECFGCCN_04109 2.7e-85 eutP E ethanolamine utilization protein EutP
NECFGCCN_04110 4.6e-123 eutQ E Ethanolamine utilization protein eutQ
NECFGCCN_04111 1.2e-143 eutT 2.5.1.17 E Cobalamin adenosyltransferase
NECFGCCN_04112 3.2e-181 pta 1.1.1.40, 2.3.1.8 C belongs to the CobB CobQ family
NECFGCCN_04113 2.6e-43 eutM CQ BMC domain
NECFGCCN_04114 6.6e-47 eutN CQ Ethanolamine utilization protein eutN
NECFGCCN_04115 9.1e-251 eutE 1.2.1.87 C Aldehyde dehydrogenase
NECFGCCN_04116 5.2e-153 eutJ E Ethanolamine utilization protein EutJ
NECFGCCN_04117 1.9e-105 eutG C alcohol dehydrogenase
NECFGCCN_04118 1e-212 L AAA ATPase domain
NECFGCCN_04120 9.7e-41 S Periplasmic Protein
NECFGCCN_04121 9.4e-24
NECFGCCN_04123 1.7e-39 M Mycolic acid cyclopropane synthetase
NECFGCCN_04126 1.4e-40 S Pyocin activator protein PrtN
NECFGCCN_04127 1.4e-72 abgT H transporter
NECFGCCN_04129 9.8e-94 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NECFGCCN_04130 5.6e-138 fnr K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NECFGCCN_04131 2.7e-182 uspE T universal stress protein
NECFGCCN_04132 9.3e-25 ydiH S Domain of unknown function
NECFGCCN_04133 4.5e-250 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NECFGCCN_04134 5.8e-275 pntA 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NECFGCCN_04135 2e-169 ydgH S Protein of unknown function (DUF1471)
NECFGCCN_04136 6.2e-244 ydgI E Arginine ornithine antiporter
NECFGCCN_04137 1e-128 IQ reductase
NECFGCCN_04138 1e-51 ydgC S membrane protein required for alginate biosynthesis
NECFGCCN_04139 5e-128 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_04140 7.4e-64
NECFGCCN_04141 3.5e-241 T PhoQ Sensor
NECFGCCN_04142 2.1e-166 tus L Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence
NECFGCCN_04143 8.7e-262 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NECFGCCN_04144 2.8e-277 ynjC P transport system permease component
NECFGCCN_04145 8e-106 ynjD S ABC transporter
NECFGCCN_04146 1e-76 ynjE 2.8.1.11 M sulfurtransferase
NECFGCCN_04147 1.4e-80 ynjE 2.8.1.11 M sulfurtransferase
NECFGCCN_04148 1.2e-33 cinA 3.5.1.42 S Belongs to the CinA family
NECFGCCN_04149 9.1e-90 yfaZ S YfaZ precursor
NECFGCCN_04150 7.5e-148 S Transposase
NECFGCCN_04151 2.9e-75 nudI L Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP)
NECFGCCN_04152 2.4e-240 menE 4.2.1.113, 6.2.1.26 IQ O-succinylbenzoic acid--CoA ligase
NECFGCCN_04153 1.4e-170 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NECFGCCN_04154 9.4e-166 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NECFGCCN_04155 1.3e-131 menH 4.2.99.20 H Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NECFGCCN_04156 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NECFGCCN_04157 1.8e-237 menF 5.4.4.2 H Catalyzes the conversion of chorismate to isochorismate
NECFGCCN_04158 7.2e-80 elaA S Acyltransferase
NECFGCCN_04159 4.8e-176 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NECFGCCN_04160 3.2e-259 nuoN 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NECFGCCN_04161 8e-285 nuoM 1.6.5.3 C NADH ubiquinone
NECFGCCN_04162 0.0 nuoL 1.6.5.3 CP NADH ubiquinone
NECFGCCN_04163 2.1e-27 nuoK 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NECFGCCN_04164 1.2e-89 nuoJ 1.6.5.3 C Belongs to the complex I subunit 6 family
NECFGCCN_04165 2.9e-88 nuoI 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NECFGCCN_04166 8.1e-182 nuoH 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NECFGCCN_04167 0.0 nuoG 1.6.5.3 C NADH-quinone oxidoreductase
NECFGCCN_04168 1.2e-268 nuoF 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NECFGCCN_04169 8.1e-93 nuoE 1.6.5.3 C NADH dehydrogenase
NECFGCCN_04170 0.0 nuoC 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NECFGCCN_04171 5.5e-129 nuoB 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NECFGCCN_04172 7.2e-77 nuoA 1.6.5.3 C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NECFGCCN_04173 4.1e-159 lrhA K Transcriptional regulator
NECFGCCN_04174 2e-238 alaA 2.6.1.2, 2.6.1.66 E in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor'
NECFGCCN_04175 7.6e-106 yfbR 3.1.3.89 S Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NECFGCCN_04176 0.0 yfbS P COG0471 Di- and tricarboxylate transporters
NECFGCCN_04177 5.2e-116 yfbT 3.1.3.23 S Phosphatase
NECFGCCN_04178 1.4e-89 yfbU S Belongs to the UPF0304 family
NECFGCCN_04179 6.9e-83 yfbV S UPF0208 membrane protein
NECFGCCN_04180 3.5e-227 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NECFGCCN_04181 0.0 pta 1.1.1.40, 2.3.1.8 C belongs to the CobB CobQ family
NECFGCCN_04182 3e-101 yfcD 2.7.6.2, 5.3.3.2 I NUDIX hydrolase
NECFGCCN_04183 2.9e-99 yfcE S Phosphoesterase
NECFGCCN_04184 1.7e-108 yfcF 2.5.1.18 O Glutathione S-transferase
NECFGCCN_04185 2.9e-116 yfcG O Belongs to the GST superfamily
NECFGCCN_04186 1.2e-61 folX 1.13.11.81, 4.1.2.25, 5.1.99.7, 5.1.99.8 H Catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate
NECFGCCN_04187 2.7e-171 yfcH CH epimerase
NECFGCCN_04188 4.4e-89 J PFAM GCN5-related N-acetyltransferase
NECFGCCN_04189 8.8e-139 hisP 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_04190 7.9e-126 hisM P ABC transporter (permease)
NECFGCCN_04191 5.8e-118 hisQ P (ABC) transporter
NECFGCCN_04192 4.4e-138 hisJ ET belongs to the bacterial solute-binding protein 3 family
NECFGCCN_04193 8.1e-140 argT ET belongs to the bacterial solute-binding protein 3 family
NECFGCCN_04194 2.3e-96 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NECFGCCN_04195 2.6e-291 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NECFGCCN_04196 3.5e-85 cvpA S Colicin v production
NECFGCCN_04197 1e-90 dedD D Non-essential cell division protein that could be required for efficient cell constriction
NECFGCCN_04198 2.5e-231 folC 6.3.2.12, 6.3.2.17 H Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives
NECFGCCN_04199 4.5e-172 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NECFGCCN_04200 3.8e-114 dedA I Pfam SNARE associated Golgi protein
NECFGCCN_04201 7.8e-154 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NECFGCCN_04202 2.2e-182 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NECFGCCN_04203 3.3e-211 pdxB 1.1.1.290 H Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
NECFGCCN_04204 3e-168 flk N Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar- associated type III secretion
NECFGCCN_04205 2.2e-151 yfcJ EGP Major facilitator Superfamily
NECFGCCN_04206 2.4e-199 pmrB EGP Major facilitator Superfamily
NECFGCCN_04207 6.6e-140 ccmI O cytochrome complex assembly
NECFGCCN_04208 1.7e-73 ccmH P subunit of a heme lyase
NECFGCCN_04209 3e-104 dsbE CO Thiol disulfide interchange protein
NECFGCCN_04210 0.0 ccmF O Cytochrome c-type biogenesis protein
NECFGCCN_04211 5.5e-80 ccmE O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NECFGCCN_04212 5.8e-30 ccmD U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NECFGCCN_04213 3e-112 ccmC U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NECFGCCN_04214 3.5e-104 ccmB 3.6.3.41 U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NECFGCCN_04215 1.6e-56 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NECFGCCN_04216 7.4e-100 nusG K Participates in transcription elongation, termination and antitermination
NECFGCCN_04217 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NECFGCCN_04218 7.1e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NECFGCCN_04219 7.8e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NECFGCCN_04220 3.2e-46 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NECFGCCN_04221 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECFGCCN_04222 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECFGCCN_04223 1.2e-242 dcuB S Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NECFGCCN_04224 5e-48 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase System
NECFGCCN_04225 7e-47 chbB 2.7.1.196, 2.7.1.205 G Phosphotransferase System
NECFGCCN_04226 8.6e-287 T Diguanylate cyclase
NECFGCCN_04227 7.4e-219 thiH 4.1.99.19 C In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS
NECFGCCN_04228 5.5e-133 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NECFGCCN_04229 6.6e-30 thiS 2.8.1.10 H thiamine biosynthesis protein ThiS
NECFGCCN_04230 2.3e-131 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NECFGCCN_04231 8.3e-111 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NECFGCCN_04232 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NECFGCCN_04233 3.2e-89 rsd K Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
NECFGCCN_04234 2e-151 nudC 1.3.7.1, 3.6.1.22 L nadh pyrophosphatase
NECFGCCN_04235 7e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NECFGCCN_04236 3.3e-126 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NECFGCCN_04237 4.4e-106 yjaG S Protein of unknown function (DUF416)
NECFGCCN_04238 9.6e-40 hupA L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NECFGCCN_04239 3.2e-116 yjaH S Protein of unknown function (DUF1481)
NECFGCCN_04240 1.2e-47 zraP NPTU Binds zinc. Could be an important component of the zinc- balancing mechanism
NECFGCCN_04241 2.9e-241 zraS 2.7.13.3 T Member of the two-component regulatory system ZraS ZraR. May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium
NECFGCCN_04242 2.4e-237 zraR T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
NECFGCCN_04243 9.9e-244 purD 6.3.4.13 F Belongs to the GARS family
NECFGCCN_04244 5e-298 purH 2.1.2.3, 3.5.4.10 F bifunctional purine biosynthesis protein purh
NECFGCCN_04246 6.4e-30 bfd P Bacterioferritin-associated ferredoxin
NECFGCCN_04247 2.5e-83 bfr 1.16.3.1 P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex
NECFGCCN_04248 5.9e-78 hopD 3.4.23.43 NOU Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NECFGCCN_04249 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NECFGCCN_04250 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NECFGCCN_04251 8e-103 rplD J Forms part of the polypeptide exit tunnel
NECFGCCN_04252 2.4e-47
NECFGCCN_04253 6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NECFGCCN_04254 1.9e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NECFGCCN_04255 2.3e-51 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NECFGCCN_04256 6.5e-125 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NECFGCCN_04257 2.1e-70 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NECFGCCN_04258 2e-23 rpmC J Belongs to the universal ribosomal protein uL29 family
NECFGCCN_04259 1.2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NECFGCCN_04260 1e-63
NECFGCCN_04261 1.2e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NECFGCCN_04262 4.9e-96 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NECFGCCN_04263 1.3e-48 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NECFGCCN_04264 8.1e-64 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NECFGCCN_04265 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NECFGCCN_04266 4.3e-48
NECFGCCN_04267 1.3e-85
NECFGCCN_04268 3.7e-24 rpmD J Ribosomal protein L30
NECFGCCN_04269 7.8e-60 rplO J binds to the 23S rRNA
NECFGCCN_04270 2.5e-242 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NECFGCCN_04271 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NECFGCCN_04272 5.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NECFGCCN_04273 5.9e-67 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NECFGCCN_04274 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NECFGCCN_04275 1.1e-181 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECFGCCN_04276 8.8e-63 rplQ J Ribosomal protein L17
NECFGCCN_04277 6e-61 yhdN S PFAM DnaJ homologue, subfamily C, member 28, conserved domain
NECFGCCN_04278 1.3e-64 zntR K transcriptional regulator
NECFGCCN_04279 4.1e-30 arfA S Domain of unknown function
NECFGCCN_04280 1.8e-66 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NECFGCCN_04281 1.5e-253 trkA P found to be peripherally associated with the inner membrane in Escherichia coli
NECFGCCN_04282 2.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NECFGCCN_04283 4.8e-171 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NECFGCCN_04284 8.8e-84 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NECFGCCN_04285 4.5e-149 dipZ CO cytochrome c biogenesis protein
NECFGCCN_04286 3.7e-37 pepN 3.4.11.2 E aminopeptidase
NECFGCCN_04287 1.4e-29 pepN 3.4.11.2 E aminopeptidase
NECFGCCN_04288 1.3e-38 pepN 3.4.11.2 E aminopeptidase
NECFGCCN_04289 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
NECFGCCN_04290 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NECFGCCN_04291 1.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NECFGCCN_04292 9.1e-156 pstA P phosphate transport system permease
NECFGCCN_04293 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
NECFGCCN_04294 1e-63 pstS P phosphate
NECFGCCN_04295 3.9e-28 pstS P phosphate
NECFGCCN_04296 5.5e-100 S oxidoreductase
NECFGCCN_04297 9.5e-189 S Protein of unknown function (DUF4056)
NECFGCCN_04298 1.1e-95 cybB C Cytochrome B561
NECFGCCN_04299 1.4e-41 frmR S protein conserved in bacteria
NECFGCCN_04300 1.4e-217 frmA 1.1.1.1, 1.1.1.284 C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily
NECFGCCN_04301 0.0 quiA 1.1.5.8 G Dehydrogenase
NECFGCCN_04302 3.5e-166 pcaQ K transcriptional regulator
NECFGCCN_04303 7.6e-117 pcaG 1.13.11.3 Q protocatechuate 3,4-dioxygenase
NECFGCCN_04304 5.5e-146 pcaH 1.13.11.3 Q protocatechuate 3,4-dioxygenase
NECFGCCN_04305 1.1e-250 ydcJ S protein conserved in bacteria
NECFGCCN_04306 9e-289 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NECFGCCN_04307 3.8e-196 1.1.1.90 C COG1062 Zn-dependent alcohol dehydrogenases, class III
NECFGCCN_04308 0.0 mdoD P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NECFGCCN_04309 1.8e-96 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NECFGCCN_04310 2.3e-120 ydcK 5.4.2.9 JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NECFGCCN_04311 3.4e-175 tehA P PFAM C4-dicarboxylate transporter malic acid transport protein
NECFGCCN_04312 1.4e-104 tehB 2.1.1.265 Q Tellurite resistance protein TehB
NECFGCCN_04313 1e-119 ydcL S Protein of unknown function (DUF3313)
NECFGCCN_04314 8.6e-162 BP3797 EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_04315 8.6e-167 tetD K AraC family transcriptional regulator
NECFGCCN_04316 9.1e-180 ydcO Q protein involved in benzoate metabolism
NECFGCCN_04317 3.8e-99 ydcN K transcriptional regulator
NECFGCCN_04318 0.0 ydcP O peptidase U32
NECFGCCN_04319 1.9e-28 yncJ S Protein of unknown function (DUF2554)
NECFGCCN_04320 2e-197 vanY 3.4.17.14, 3.5.1.28, 4.1.1.105, 4.1.1.28 GH23 M D-alanyl-D-alanine carboxypeptidase
NECFGCCN_04322 4.7e-188 O ATPase (AAA
NECFGCCN_04323 0.0 O Subtilase family
NECFGCCN_04325 4.8e-288 mscS M Mechanosensitive ion channel
NECFGCCN_04326 2.3e-56 fumB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
NECFGCCN_04327 8.7e-125 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NECFGCCN_04328 2e-35 puuA 6.3.1.11, 6.3.1.2 E glutamine synthetase
NECFGCCN_04329 5.6e-146 puuD 3.5.1.94 E Gamma-glutamyl-gamma-aminobutyrate hydrolase
NECFGCCN_04330 1.6e-94 puuR K Helix-turn-helix domain
NECFGCCN_04331 6.4e-279 puuC 1.2.1.3, 1.2.1.54, 1.2.1.99 C belongs to the aldehyde dehydrogenase family
NECFGCCN_04332 3.7e-251 puuB E oxidoreductase
NECFGCCN_04333 2.7e-174 dmlR K Transcriptional regulator
NECFGCCN_04334 1.9e-211 dmlA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NECFGCCN_04335 9.9e-294 yeaV M Belongs to the BCCT transporter (TC 2.A.15) family
NECFGCCN_04336 7.8e-229 yeaW 1.14.13.239 P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
NECFGCCN_04337 9e-270 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
NECFGCCN_04338 2.1e-169 yeaX 1.14.13.238, 1.14.13.239 C Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1
NECFGCCN_04339 0.0 ptsA 2.7.1.121, 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NECFGCCN_04340 6.2e-191 frwC G pts system
NECFGCCN_04341 6e-49 frwB G FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell
NECFGCCN_04342 0.0 pflD 2.3.1.54 C Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde
NECFGCCN_04343 9.2e-169 pflC 1.97.1.4 O glycyl-radical enzyme activating protein family
NECFGCCN_04344 1.6e-55 fruA 2.7.1.202, 2.7.1.56 G pts system
NECFGCCN_04345 1.9e-146 Q Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin
NECFGCCN_04346 2.5e-155 K transcriptional regulator
NECFGCCN_04347 1.1e-169 T (GGDEF) domain
NECFGCCN_04348 1.2e-186 fbpC 3.6.3.30 P Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system
NECFGCCN_04349 4.7e-280 sfuB P ABC-type Fe3 transport system permease component
NECFGCCN_04350 1.9e-189 fbpA P ABC-type Fe3 transport system, periplasmic component
NECFGCCN_04351 5.8e-259 ycgG T Diguanylate phosphodiesterase
NECFGCCN_04352 6.2e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
NECFGCCN_04353 0.0 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NECFGCCN_04355 1e-309 oppA-1 E ABC transporter substrate-binding protein
NECFGCCN_04356 2.1e-93 yccA S Belongs to the BI1 family
NECFGCCN_04357 6.8e-56 tusE P part of a sulfur-relay system
NECFGCCN_04358 6.4e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NECFGCCN_04359 2.7e-135 ybcM K transcriptional regulator
NECFGCCN_04360 5.4e-98 ybcL S PFAM PEBP family protein
NECFGCCN_04361 2.4e-231 rlmI 2.1.1.191 J Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA
NECFGCCN_04362 8.8e-53 hspQ S Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress
NECFGCCN_04363 1.9e-137
NECFGCCN_04364 0.0 murF 6.3.2.10 M PFAM Glycosyl transferase, group 1
NECFGCCN_04365 1.8e-210 M TIGRFAM type I secretion membrane fusion protein, HlyD
NECFGCCN_04366 0.0 V ABC transporter, transmembrane region
NECFGCCN_04367 4.2e-235 MU Outer membrane efflux protein
NECFGCCN_04368 9.6e-215 pic 3.4.24.40 Q von willebrand factor, type A
NECFGCCN_04369 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NECFGCCN_04370 7.6e-128 gspC U General secretion pathway protein C
NECFGCCN_04371 0.0 gspD NU General Secretion Pathway protein
NECFGCCN_04372 1.1e-273 gspE NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NECFGCCN_04373 1.8e-199 gspF U general secretion pathway protein
NECFGCCN_04374 4.9e-75 gspG U General Secretion Pathway protein
NECFGCCN_04375 7.5e-86 gspH NU general secretion pathway protein
NECFGCCN_04376 2.5e-59 NU general secretion pathway protein
NECFGCCN_04377 4.8e-100 gspJ U General secretion pathway protein J
NECFGCCN_04378 5.3e-44 gspK U COG3156 Type II secretory pathway component PulK
NECFGCCN_04379 1e-21
NECFGCCN_04380 1.6e-248 S dextransucrase activity
NECFGCCN_04382 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NECFGCCN_04383 8.7e-265 yeeO V Mate efflux family protein
NECFGCCN_04384 1.2e-221 XK27_05470 E Methionine synthase
NECFGCCN_04385 1.2e-70 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NECFGCCN_04386 6e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NECFGCCN_04387 1.1e-176 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
NECFGCCN_04388 1.8e-164 ET ABC transporter substrate-binding protein
NECFGCCN_04389 1e-109 ytmL P ABC transporter (Permease
NECFGCCN_04390 5.4e-113 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NECFGCCN_04391 1.2e-77 ypmB S Protein conserved in bacteria
NECFGCCN_04392 6.3e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NECFGCCN_04393 5.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NECFGCCN_04394 9.8e-228 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NECFGCCN_04395 1.1e-101 rsmC 2.1.1.172 J Methyltransferase small domain protein
NECFGCCN_04396 1.2e-169 coaA 2.7.1.33 F Pantothenic acid kinase
NECFGCCN_04397 2.8e-154 E Alpha/beta hydrolase of unknown function (DUF915)
NECFGCCN_04398 6.4e-227 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_04399 3.7e-111 drgA C nitroreductase
NECFGCCN_04400 1.5e-102 yoaK S Protein of unknown function (DUF1275)
NECFGCCN_04401 7.1e-158 yvgN C reductase
NECFGCCN_04402 1.3e-207 S Tetratricopeptide repeat
NECFGCCN_04403 5.8e-131 clpB O C-terminal, D2-small domain, of ClpB protein
NECFGCCN_04404 2e-44
NECFGCCN_04405 2e-53 I mechanosensitive ion channel activity
NECFGCCN_04406 2.1e-25
NECFGCCN_04407 5.5e-17 M LysM domain
NECFGCCN_04408 1.4e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NECFGCCN_04409 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NECFGCCN_04410 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NECFGCCN_04411 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NECFGCCN_04412 1.1e-75 XK27_03610 K Gnat family
NECFGCCN_04413 5.6e-89 yybC
NECFGCCN_04414 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NECFGCCN_04415 4.1e-267 pepV 3.5.1.18 E Dipeptidase
NECFGCCN_04416 2e-106 ung2 3.2.2.27 L Uracil-DNA glycosylase
NECFGCCN_04418 2.8e-13 V Glucan-binding protein C
NECFGCCN_04419 1.2e-26 V Glucan-binding protein C
NECFGCCN_04424 7e-17 zur K Belongs to the Fur family
NECFGCCN_04425 4.5e-16 S Protein of unknown function (DUF2969)
NECFGCCN_04426 1.7e-198 ilvE 2.6.1.42 E Aminotransferase
NECFGCCN_04427 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NECFGCCN_04428 1.1e-35 codA 3.5.4.1 F cytosine deaminase
NECFGCCN_04430 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NECFGCCN_04431 1.7e-54 nirD 1.7.1.15 P Nitrite reductase
NECFGCCN_04432 3.7e-257 cysG 1.3.1.76, 2.1.1.107, 2.1.1.131, 3.7.1.12, 4.2.1.75, 4.99.1.3, 4.99.1.4 H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NECFGCCN_04433 2.9e-190 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NECFGCCN_04434 2.4e-141 gph 3.1.3.18 G Phosphoglycolate phosphatase
NECFGCCN_04435 1.5e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NECFGCCN_04436 2.2e-156 dam 2.1.1.72 L Site-specific DNA-methyltransferase (Adenine-specific)
NECFGCCN_04437 1.6e-108 damX D Cell division protein DamX
NECFGCCN_04438 7.4e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NECFGCCN_04439 1.9e-89 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NECFGCCN_04440 6.2e-211 pilQ U (Type IV) pilus
NECFGCCN_04441 7.5e-23
NECFGCCN_04442 2.5e-60 hofN NU carbon utilization
NECFGCCN_04443 4.1e-131 hofM NU Pilus assembly protein
NECFGCCN_04444 0.0 mrcA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NECFGCCN_04445 3.6e-97 nudE L Hydrolase
NECFGCCN_04446 0.0 yrfF S Intracellular growth attenuator
NECFGCCN_04447 3.7e-133 yrfG 3.1.3.5 E Hydrolase
NECFGCCN_04448 4e-66 hslR J Belongs to the HSP15 family
NECFGCCN_04449 3.4e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NECFGCCN_04450 0.0 pckA 4.1.1.49 H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NECFGCCN_04451 1e-254 T PhoQ Sensor
NECFGCCN_04452 5.7e-132 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_04453 7.5e-85 greB K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length
NECFGCCN_04454 0.0 yhgF K accessory protein
NECFGCCN_04455 2.3e-34 feoA P Fe2 transport system protein A
NECFGCCN_04456 0.0 feoB P Transporter of a GTP-driven Fe(2 ) uptake system
NECFGCCN_04457 3.7e-35 feoC K metal cluster binding
NECFGCCN_04458 1.9e-40 yahO S Protein of unknown function (DUF1471)
NECFGCCN_04459 3.8e-142 bioH 2.1.1.197, 3.1.1.85 S The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters
NECFGCCN_04460 4.1e-124 comF S Competence protein
NECFGCCN_04461 2.8e-105 nfuA C Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NECFGCCN_04462 4.7e-225 gntT EG Gluconate
NECFGCCN_04463 0.0 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NECFGCCN_04464 0.0 malP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NECFGCCN_04465 0.0 malT K Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'
NECFGCCN_04466 1.8e-136 glpR K transcriptional regulator
NECFGCCN_04467 4.2e-155 glpG S Rhomboid-type serine protease that catalyzes intramembrane proteolysis
NECFGCCN_04468 3.3e-58 glpE 2.8.1.1 P Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide
NECFGCCN_04469 1.7e-295 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NECFGCCN_04470 2.2e-60 S protein conserved in bacteria
NECFGCCN_04471 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NECFGCCN_04472 1.5e-280 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NECFGCCN_04473 1.5e-252 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NECFGCCN_04474 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NECFGCCN_04475 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NECFGCCN_04476 3.6e-210 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NECFGCCN_04477 6.4e-238 gntU EG Gluconate
NECFGCCN_04478 2e-94 gntK 2.7.1.12 F Gluconokinase
NECFGCCN_04479 2.8e-185 gntR K Transcriptional
NECFGCCN_04480 5.5e-132 yhhW S Belongs to the pirin family
NECFGCCN_04481 4.7e-196 yhhX 1.1.1.371 S oxidoreductase
NECFGCCN_04482 5.4e-89 M COG1664 Integral membrane protein CcmA involved in cell shape determination
NECFGCCN_04483 9e-89 yhhY 2.3.1.178 J acetyltransferase
NECFGCCN_04484 0.0 ggt 2.3.2.2, 3.4.19.13 M Gamma-glutamyltransferase
NECFGCCN_04485 1.1e-23 yhhA S Protein of unknown function (DUF2756)
NECFGCCN_04486 1e-139 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NECFGCCN_04487 2.8e-199 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
NECFGCCN_04488 7.9e-149 ugpE P probably responsible for the translocation of the substrate across the membrane
NECFGCCN_04489 1.8e-159 ugpA P With UgpEC is involved in the uptake of glycerol-3-phosphate
NECFGCCN_04490 1.1e-255 ugpB G ABC transporter substrate-binding protein
NECFGCCN_04491 6.7e-107 VM57_08315 3.2.2.10 S Belongs to the LOG family
NECFGCCN_04493 1.5e-64 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NECFGCCN_04494 1e-17 malI K Transcriptional regulator
NECFGCCN_04495 6.4e-269 ydgA S protein conserved in bacteria
NECFGCCN_04496 1.4e-217 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G Belongs to the mannose-6-phosphate isomerase type 1 family
NECFGCCN_04497 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NECFGCCN_04498 8.2e-44 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NECFGCCN_04499 7.2e-96 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NECFGCCN_04500 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
NECFGCCN_04501 0.0
NECFGCCN_04502 1.3e-93 NU Protein of unknown function (DUF3131)
NECFGCCN_04503 0.0 2.4.1.12 GT2 M Cellulose synthase
NECFGCCN_04504 6.5e-229 S OpgC protein
NECFGCCN_04505 5.6e-177
NECFGCCN_04506 1.7e-229 3.1.3.3 T response regulator
NECFGCCN_04507 7.2e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NECFGCCN_04508 4.3e-80 2.7.11.1 T Anti-sigma regulatory factor (Ser Thr protein kinase)
NECFGCCN_04509 9.4e-18
NECFGCCN_04510 3.1e-159 K transcriptional regulator
NECFGCCN_04511 3.2e-125 IQ KR domain
NECFGCCN_04512 2.4e-148 S HD superfamily
NECFGCCN_04513 2e-103 pfpI 3.5.1.124 S Intracellular protease
NECFGCCN_04514 1.3e-82 tssB S type VI secretion protein
NECFGCCN_04515 1.2e-83 S type VI secretion protein
NECFGCCN_04516 3.2e-30 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
NECFGCCN_04517 0.0 U Type IV secretory system Conjugative DNA transfer
NECFGCCN_04518 2.6e-127 mobC K Transcriptional regulator
NECFGCCN_04519 1.5e-164 L Domain of unknown function (DUF1738)
NECFGCCN_04520 1.9e-132 K PGAP1-like protein
NECFGCCN_04521 9.5e-17
NECFGCCN_04522 6.2e-213 L ATPase involved in DNA repair
NECFGCCN_04523 4.1e-15
NECFGCCN_04525 0.0 pcrA1 3.6.4.12 L PFAM UvrD REP helicase
NECFGCCN_04526 8.2e-289 L AAA ATPase domain
NECFGCCN_04527 7.4e-95
NECFGCCN_04528 1.7e-66 yjgH J Translation Initiation Inhibitor YjgF Family
NECFGCCN_04529 9.1e-159 K transcriptional regulator
NECFGCCN_04530 1.2e-174 erfK S Catalyzes th removal of D-alanine and attachment of the murein lipoprotein to the peptidoglycan tetrapeptide chain
NECFGCCN_04531 5.3e-178 cbl K transcriptional regulator
NECFGCCN_04532 3.5e-158 nac K transcriptional regulator
NECFGCCN_04533 1.1e-175 P ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NECFGCCN_04534 6.3e-257 sdaB 4.3.1.17 E l-serine dehydratase
NECFGCCN_04535 1.7e-227 sdaC E Serine transporter
NECFGCCN_04536 2.5e-261 ygdH 3.2.2.10 S Rossmann fold nucleotide-binding protein
NECFGCCN_04537 4.7e-162 queF 1.7.1.13 K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NECFGCCN_04538 2.3e-93 syd S regulation of protein complex assembly
NECFGCCN_04539 2e-55 yqcC 3.5.1.28, 5.1.3.13, 5.4.99.26 S protein conserved in bacteria
NECFGCCN_04540 6.7e-150 truC 5.4.99.26 J Pseudouridine synthase
NECFGCCN_04541 1e-78 yqcA C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NECFGCCN_04542 6.5e-254 gudP G transporter
NECFGCCN_04543 4.3e-266 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NECFGCCN_04544 1.5e-263 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NECFGCCN_04545 9.1e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NECFGCCN_04546 0.0 barA 2.7.13.3 T PhoQ Sensor
NECFGCCN_04547 4.5e-244 rlmD 2.1.1.190 J Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA
NECFGCCN_04548 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NECFGCCN_04549 2.5e-144 mazG 3.6.1.66, 3.6.1.9 C nucleoside triphosphate pyrophosphohydrolase
NECFGCCN_04550 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NECFGCCN_04551 3.1e-237 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NECFGCCN_04552 1.2e-205 hetM GM Male sterility protein
NECFGCCN_04553 1.9e-129 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NECFGCCN_04554 5.9e-69 queD 4.1.2.50, 4.2.3.12 H synthase
NECFGCCN_04555 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NECFGCCN_04556 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 C Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NECFGCCN_04557 1.7e-136 cysH 1.8.4.10, 1.8.4.8 C Belongs to the PAPS reductase family. CysH subfamily
NECFGCCN_04558 1.3e-185 iap S Peptidase family M28
NECFGCCN_04559 1.5e-253 cysG 1.3.1.76, 2.1.1.107, 2.1.1.131, 3.7.1.12, 4.2.1.75, 4.99.1.3, 4.99.1.4 H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NECFGCCN_04560 4e-175 cysD 1.8.4.10, 1.8.4.8, 2.7.7.4 H sulfate adenylyltransferase), subunit 2
NECFGCCN_04561 1.7e-268 cysN 2.7.1.25, 2.7.7.4 H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
NECFGCCN_04562 2.7e-111 cysC 2.7.1.25 F Catalyzes the synthesis of activated sulfate
NECFGCCN_04563 3.2e-50 ygbE S membrane
NECFGCCN_04564 1.7e-51 ftsB D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NECFGCCN_04565 4.9e-128 ispD 2.7.7.60 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NECFGCCN_04566 1.8e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NECFGCCN_04567 1.9e-197 truD 5.4.99.27 J Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs
NECFGCCN_04568 1.6e-132 surE 3.1.3.5 S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NECFGCCN_04569 5.2e-113 pcm 2.1.1.77 J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NECFGCCN_04570 1.5e-134 nlpD DM COG0739 Membrane proteins related to metalloendopeptidases
NECFGCCN_04571 5.5e-178 rpoS K RNA polymerase sigma
NECFGCCN_04572 7.5e-59 S protein conserved in bacteria
NECFGCCN_04573 9.3e-212 EGP Major facilitator Superfamily
NECFGCCN_04574 1.6e-152 ptxR K transcriptional regulator
NECFGCCN_04575 4.9e-64 hosA K Transcriptional regulator
NECFGCCN_04576 3.4e-106 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NECFGCCN_04577 6.6e-281 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate and vanillate
NECFGCCN_04578 4.4e-41 bsdD 4.1.1.61 S 4-hydroxybenzoate decarboxylase
NECFGCCN_04579 1.1e-16 hokE S Hok/gef family
NECFGCCN_04580 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NECFGCCN_04581 4.4e-146 hmuV 1.14.15.20, 3.6.3.33, 3.6.3.34 P Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NECFGCCN_04582 3.6e-161 hmuU P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_04583 2.6e-141 hmuT P ABC-type hemin transport system, periplasmic component
NECFGCCN_04584 9.8e-194 hmuS P hemin transport protein
NECFGCCN_04585 0.0 hpuB P Receptor
NECFGCCN_04586 2.2e-50 O protein conserved in bacteria
NECFGCCN_04587 0.0 2.2.1.6 EH COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase
NECFGCCN_04588 1.9e-135 ywkB S transporter
NECFGCCN_04589 5.2e-159 K LysR substrate binding domain
NECFGCCN_04590 1.5e-58 ygbA S Nitrous oxide-stimulated promoter
NECFGCCN_04591 4.2e-142 sitD P COG1108 ABC-type Mn2 Zn2 transport systems permease components
NECFGCCN_04592 1e-148 sitC P iron transport system membrane protein
NECFGCCN_04593 1.9e-147 sitB P (ABC) transporter
NECFGCCN_04594 2.6e-169 psaA P Belongs to the bacterial solute-binding protein 9 family
NECFGCCN_04595 1.2e-169 K transcriptional regulator
NECFGCCN_04596 2e-16 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NECFGCCN_04597 2.1e-20 6.1.1.6 S Psort location CytoplasmicMembrane, score
NECFGCCN_04599 2e-28 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NECFGCCN_04600 7.2e-71
NECFGCCN_04601 3e-170 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NECFGCCN_04602 1.9e-225 S oxidoreductase
NECFGCCN_04603 1.6e-196 dhdh S oxidoreductase
NECFGCCN_04604 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NECFGCCN_04605 7.7e-126 gntR1 K transcriptional
NECFGCCN_04606 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NECFGCCN_04607 4.9e-174 yeiH S membrane
NECFGCCN_04609 4.5e-91 adk 2.7.4.3 F topology modulation protein
NECFGCCN_04610 5.5e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NECFGCCN_04611 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NECFGCCN_04612 2.8e-35 XK27_09805 S MORN repeat protein
NECFGCCN_04613 0.0 XK27_09800 I Acyltransferase
NECFGCCN_04614 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NECFGCCN_04615 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NECFGCCN_04616 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NECFGCCN_04617 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
NECFGCCN_04618 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NECFGCCN_04619 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NECFGCCN_04620 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NECFGCCN_04621 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NECFGCCN_04622 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NECFGCCN_04623 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NECFGCCN_04624 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NECFGCCN_04625 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NECFGCCN_04626 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NECFGCCN_04627 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NECFGCCN_04628 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NECFGCCN_04629 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NECFGCCN_04630 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NECFGCCN_04631 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NECFGCCN_04632 1.9e-23 rpmD J ribosomal protein l30
NECFGCCN_04633 5.7e-58 rplO J binds to the 23S rRNA
NECFGCCN_04634 3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NECFGCCN_04635 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NECFGCCN_04636 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NECFGCCN_04637 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NECFGCCN_04638 4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECFGCCN_04639 4.4e-62 rplQ J ribosomal protein l17
NECFGCCN_04640 5.1e-261 yjcE P NhaP-type Na H and K H antiporters
NECFGCCN_04641 1.3e-120 nemR K transcriptional regulator
NECFGCCN_04642 5.3e-173 yhdH C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NECFGCCN_04643 2.5e-156 S Nucleoside recognition family protein
NECFGCCN_04644 1.3e-296 3.1.1.1 I Serine aminopeptidase, S33
NECFGCCN_04645 2.4e-29 pmrD S Polymyxin resistance protein PmrD
NECFGCCN_04646 7.4e-288 amn 3.2.2.4 F Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations
NECFGCCN_04647 1.1e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
NECFGCCN_04648 2.2e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NECFGCCN_04649 2.3e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
NECFGCCN_04650 1.2e-117 manM G pts system
NECFGCCN_04651 4.5e-118 manL 2.7.1.191 G pts system
NECFGCCN_04652 1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NECFGCCN_04653 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NECFGCCN_04654 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NECFGCCN_04655 2.5e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NECFGCCN_04656 5.7e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NECFGCCN_04657 6.2e-126 IQ reductase
NECFGCCN_04658 1.8e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NECFGCCN_04659 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NECFGCCN_04660 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NECFGCCN_04661 6.4e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NECFGCCN_04662 5.2e-72 marR K Transcriptional regulator, MarR family
NECFGCCN_04663 6.2e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NECFGCCN_04664 1.5e-32 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NECFGCCN_04665 1.8e-98 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NECFGCCN_04666 1.3e-63 ybaN S Membrane
NECFGCCN_04667 3e-74 priC L primosomal replication protein
NECFGCCN_04668 1.9e-12 ybaM S Protein of unknown function (DUF2496)
NECFGCCN_04669 1.6e-147 yadD S Putative transposase, YhgA-like
NECFGCCN_04670 0.0 kefA M mechanosensitive ion channel
NECFGCCN_04671 1.4e-113 acrR K transcriptional regulator
NECFGCCN_04672 1.3e-213 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_04673 6.9e-122 narJ 1.7.5.1 C Nitrate reductase
NECFGCCN_04674 2.7e-123 narI 1.7.5.1 C nitrate reductase, gamma subunit
NECFGCCN_04675 8.9e-151 yxxF EG Multidrug DMT transporter permease
NECFGCCN_04676 5.7e-74 lrpC K AsnC family transcriptional regulator
NECFGCCN_04677 7.3e-245 proY E Amino acid permease-associated region
NECFGCCN_04678 2.3e-232 hutH 3.5.2.7, 4.3.1.3 E PFAM Phenylalanine histidine ammonia-lyase
NECFGCCN_04679 2.2e-159 cvfB S Protein conserved in bacteria
NECFGCCN_04680 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NECFGCCN_04681 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NECFGCCN_04682 6.8e-210 sptS 2.7.13.3 T Histidine kinase
NECFGCCN_04683 6e-115 T response regulator
NECFGCCN_04684 9.7e-112 2.7.6.5 S Region found in RelA / SpoT proteins
NECFGCCN_04685 1.3e-111 K Acetyltransferase (GNAT) family
NECFGCCN_04686 0.0 lmrA2 V abc transporter atp-binding protein
NECFGCCN_04687 7.5e-311 lmrA1 V abc transporter atp-binding protein
NECFGCCN_04688 1.4e-72 K DNA-binding transcription factor activity
NECFGCCN_04689 3.9e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NECFGCCN_04690 1.7e-264 S Psort location CytoplasmicMembrane, score
NECFGCCN_04691 5.7e-240 nylA 3.5.1.4 J Belongs to the amidase family
NECFGCCN_04692 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NECFGCCN_04693 5.5e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NECFGCCN_04694 2.1e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NECFGCCN_04695 5e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NECFGCCN_04696 5.2e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NECFGCCN_04697 4.4e-133 S TraX protein
NECFGCCN_04698 2.6e-13 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NECFGCCN_04699 1.8e-24
NECFGCCN_04701 1.2e-140 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NECFGCCN_04702 3.2e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NECFGCCN_04703 1.4e-08 MU outer membrane autotransporter barrel domain protein
NECFGCCN_04704 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NECFGCCN_04706 9e-75 XK27_03180 T universal stress protein
NECFGCCN_04707 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NECFGCCN_04708 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NECFGCCN_04709 5.8e-100 pncA Q isochorismatase
NECFGCCN_04710 1.9e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NECFGCCN_04711 2.9e-42 livF P Branched-chain amino acid transport
NECFGCCN_04712 7.5e-166 yjiE K transcriptional regulator
NECFGCCN_04713 0.0 pckA 4.1.1.49 H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NECFGCCN_04714 1e-84 ats 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECFGCCN_04715 2.2e-168 K transcriptional regulator
NECFGCCN_04716 3.3e-231 citA EGP Is involved in the uptake of citrate and the transport of protons into the cell
NECFGCCN_04717 1.6e-138 5.3.3.7 P ABC transporter substrate-binding protein
NECFGCCN_04718 6.5e-28 ybhD K transcriptional regulator
NECFGCCN_04719 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NECFGCCN_04720 0.0 dnaE 2.7.7.7 L DNA polymerase
NECFGCCN_04721 0.0 dmsA 1.8.5.3, 1.97.1.9 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_04722 9.7e-41 pepD E Dipeptidase
NECFGCCN_04723 1.3e-160 whiA K May be required for sporulation
NECFGCCN_04724 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NECFGCCN_04725 2e-163 rapZ S Displays ATPase and GTPase activities
NECFGCCN_04726 5.3e-136 yejC S cyclic nucleotide-binding protein
NECFGCCN_04727 1.1e-25 D nuclear chromosome segregation
NECFGCCN_04728 3.5e-51 D nuclear chromosome segregation
NECFGCCN_04729 2.6e-27 D nuclear chromosome segregation
NECFGCCN_04730 3.7e-63 XK27_02560 S cog cog2151
NECFGCCN_04731 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NECFGCCN_04732 6.3e-221 ytfP S Flavoprotein
NECFGCCN_04734 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NECFGCCN_04735 3.6e-47 ytmP 2.7.1.89 M Phosphotransferase
NECFGCCN_04736 5.6e-186 wcoF M Glycosyltransferase, group 1 family protein
NECFGCCN_04737 1.2e-09 fruR K transcriptional
NECFGCCN_04739 7e-262 mloB K Transcriptional regulator
NECFGCCN_04740 3.4e-65
NECFGCCN_04741 2e-13
NECFGCCN_04742 2.4e-61
NECFGCCN_04743 1e-198 L Replication initiation factor
NECFGCCN_04745 5.2e-281 L DNA integration
NECFGCCN_04746 2e-231
NECFGCCN_04747 4.3e-127 P ATPases associated with a variety of cellular activities
NECFGCCN_04748 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NECFGCCN_04749 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NECFGCCN_04750 3.6e-218 metE 2.1.1.14 E Methionine synthase
NECFGCCN_04751 6.1e-08 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NECFGCCN_04752 7.5e-59 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NECFGCCN_04753 4e-237 hisS 6.1.1.21 J histidyl-tRNA synthetase
NECFGCCN_04755 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NECFGCCN_04756 1e-128 XK27_01785 S cog cog1284
NECFGCCN_04757 3.5e-118 yaaA S Belongs to the UPF0246 family
NECFGCCN_04758 1.3e-113 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NECFGCCN_04759 1.1e-84 XK27_10930 K acetyltransferase
NECFGCCN_04760 7.5e-14
NECFGCCN_04761 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NECFGCCN_04762 1.1e-287 ccs S the current gene model (or a revised gene model) may contain a frame shift
NECFGCCN_04763 2.1e-43 yrzB S Belongs to the UPF0473 family
NECFGCCN_04764 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NECFGCCN_04765 6.3e-44 yrzL S Belongs to the UPF0297 family
NECFGCCN_04766 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NECFGCCN_04767 3.5e-233 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NECFGCCN_04769 9.4e-214 int L Phage integrase family
NECFGCCN_04770 1.4e-18 S Domain of unknown function (DUF3173)
NECFGCCN_04771 1.5e-109 L Replication initiation factor
NECFGCCN_04772 5.5e-89 K sequence-specific DNA binding
NECFGCCN_04773 4.2e-43 C Succinate dehydrogenase fumarate reductase, flavoprotein subunit
NECFGCCN_04774 1.8e-25 C Succinate dehydrogenase fumarate reductase, flavoprotein subunit
NECFGCCN_04775 3.4e-52 S NIPSNAP family containing protein
NECFGCCN_04776 0.0 C Succinate dehydrogenase fumarate reductase, flavoprotein subunit
NECFGCCN_04777 1.8e-142 aroE 1.1.1.25, 4.2.1.10 E shikimate dehydrogenase
NECFGCCN_04778 1.2e-135 pcaR K Transcriptional regulator
NECFGCCN_04779 1.2e-07
NECFGCCN_04780 1.1e-161 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NECFGCCN_04781 9.6e-26 cyoD C PFAM Cytochrome C oxidase subunit IV
NECFGCCN_04782 2.9e-113 cyoC C oxidase subunit
NECFGCCN_04783 0.0 cyoB 1.10.3.10, 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NECFGCCN_04784 8.4e-176 cyoA 1.10.3.10, 1.10.3.12 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NECFGCCN_04785 1.6e-266 ampG EGP Major facilitator Superfamily
NECFGCCN_04786 2.1e-97 yajG M Lipoprotein
NECFGCCN_04787 5.1e-53 bolA T Belongs to the BolA IbaG family
NECFGCCN_04788 6e-233 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NECFGCCN_04789 6.1e-114 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NECFGCCN_04790 4e-237 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NECFGCCN_04791 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NECFGCCN_04792 4.8e-39 hupB L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NECFGCCN_04793 6.3e-308 ppiD 5.2.1.8 O peptidylprolyl isomerase
NECFGCCN_04794 1.6e-53 ybaV 3.1.26.11 L Competence protein ComEA
NECFGCCN_04795 1.2e-67 tesC S Thioesterase
NECFGCCN_04796 8e-131 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NECFGCCN_04797 0.0 ybaE S ABC transporter substrate-binding protein
NECFGCCN_04798 1.2e-157 cof S Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P)
NECFGCCN_04799 1.3e-198 cysK_2 2.5.1.47 E cysteine synthase
NECFGCCN_04800 1.8e-78 ybaO K transcriptional regulator
NECFGCCN_04801 2.9e-302 mdlA V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
NECFGCCN_04802 0.0 mdlB V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
NECFGCCN_04803 1.1e-53 glnK K Belongs to the P(II) protein family
NECFGCCN_04804 2e-236 amtB P Ammonium transporter
NECFGCCN_04805 2.6e-163 tesB I Acyl-CoA thioesterase
NECFGCCN_04806 4e-68 ybaY S protein conserved in bacteria
NECFGCCN_04807 1.3e-53 ybaZ 2.1.1.63 L methylated DNA-protein cysteine methyltransferase
NECFGCCN_04808 4.6e-62
NECFGCCN_04809 6.1e-36
NECFGCCN_04810 3e-36
NECFGCCN_04811 2.3e-265 K Transcriptional regulator
NECFGCCN_04812 4e-102 S Membrane
NECFGCCN_04813 3.9e-124 rcnA U Belongs to the NiCoT transporter (TC 2.A.52) family
NECFGCCN_04814 3.3e-40 rcnR S protein conserved in bacteria
NECFGCCN_04815 1e-295 ylaB 3.1.4.52 T signal transduction protein containing sensor and EAL
NECFGCCN_04816 1.2e-210 ganK P Belongs to the ABC transporter superfamily
NECFGCCN_04817 1.5e-228 cycB G Functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis
NECFGCCN_04818 2.8e-246 malC P transport
NECFGCCN_04819 2.7e-149 ganQ P transport
NECFGCCN_04820 1.7e-237 ganB 3.2.1.89 G Arabinogalactan endo-beta-1,4-galactanase
NECFGCCN_04821 0.0 bglY 3.2.1.23 G beta-galactosidase
NECFGCCN_04822 8.5e-48 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Phosphotransferase System
NECFGCCN_04823 2.4e-250 lamB M involved in the transport of maltose and maltodextrins
NECFGCCN_04824 5e-193 lacI K binds specific sites in lac operon resulting in DNA looping between the operators
NECFGCCN_04825 2.6e-42 rpmE2 J Ribosomal protein L31
NECFGCCN_04826 7e-18 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NECFGCCN_04827 1.2e-129 ydaF_2 J Acetyltransferases including N-acetylases of ribosomal proteins
NECFGCCN_04828 2.4e-246 gabR_4 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_04829 3.3e-80 ylaC S Membrane
NECFGCCN_04830 7.2e-90 maa 2.3.1.79 S acetyltransferase, isoleucine patch superfamily
NECFGCCN_04831 1.4e-33 hha S Haemolysin expression modulating protein
NECFGCCN_04832 2e-67 tomB S Biofilm formation regulator YbaJ
NECFGCCN_04833 1.7e-70 acrB V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_04834 1.2e-249 2.6.1.55 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NECFGCCN_04835 2.1e-137 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_04836 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_04837 2.5e-113 E (ABC) transporter
NECFGCCN_04838 1.8e-105 E (ABC) transporter
NECFGCCN_04839 2.9e-159 ET ABC transporter substrate-binding protein
NECFGCCN_04840 3.1e-286 gabR_2 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_04841 6.2e-249 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_04842 3.4e-153 ydeK EG transporter
NECFGCCN_04843 3e-245 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia
NECFGCCN_04844 1.6e-185 dppD 3.6.3.24 P Belongs to the ABC transporter superfamily
NECFGCCN_04845 1.4e-192 MA20_19370 E Belongs to the ABC transporter superfamily
NECFGCCN_04846 1.2e-155 MA20_19380 EP N-terminal TM domain of oligopeptide transport permease C
NECFGCCN_04847 2.6e-172 MA20_19385 EP Binding-protein-dependent transport system inner membrane component
NECFGCCN_04848 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
NECFGCCN_04849 6.2e-218 ybdK H ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NECFGCCN_04850 2.8e-118 yigE S Phosphodiester glycosidase
NECFGCCN_04851 0.0 bepG V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_04852 3.4e-149 bepF M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_04853 0.0 ctpF P ATPase, P-type (transporting), HAD superfamily, subfamily IC
NECFGCCN_04854 1e-164 recC 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NECFGCCN_04856 4.7e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NECFGCCN_04857 3.1e-63 yfeD L Putative transcription regulator (DUF1323)
NECFGCCN_04858 1.9e-56 yfeC L Negative Regulator
NECFGCCN_04859 0.0 3.5.1.28 NU amidase activity
NECFGCCN_04861 7.7e-76 aroH 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NECFGCCN_04862 1.4e-31 hemP P Hemin uptake protein
NECFGCCN_04863 5.1e-281 ydiU S Belongs to the UPF0061 (SELO) family
NECFGCCN_04864 1e-86 nlpC 3.4.17.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NECFGCCN_04865 3.8e-131 btuD 3.6.3.33 P Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NECFGCCN_04866 2.9e-99 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NECFGCCN_04867 2.1e-143 metQ P Belongs to the NlpA lipoprotein family
NECFGCCN_04868 8.3e-174 btuC H Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane
NECFGCCN_04869 2.1e-242 S antiporter activity
NECFGCCN_04870 6.5e-165 VPA0331 K Transcriptional regulator
NECFGCCN_04871 6.5e-232 dadA2 1.4.5.1 C D-amino acid dehydrogenase
NECFGCCN_04872 2.2e-55 J Translation Initiation Inhibitor YjgF Family
NECFGCCN_04873 8.1e-48 himA K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
NECFGCCN_04874 2e-169 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NECFGCCN_04875 1.8e-24 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NECFGCCN_04876 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NECFGCCN_04877 2.4e-207 rny D Endoribonuclease that initiates mRNA decay
NECFGCCN_04878 3.3e-26 fruR K transcriptional
NECFGCCN_04879 7.7e-83 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NECFGCCN_04880 1.3e-105 mobA 2.10.1.1, 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NECFGCCN_04881 7e-43 yihD S protein conserved in bacteria
NECFGCCN_04882 2.5e-194 srkA F A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NECFGCCN_04883 1.1e-112 dsbA O Thiol disulfide interchange protein
NECFGCCN_04884 3.1e-167 yihG I Acyltransferase
NECFGCCN_04885 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NECFGCCN_04886 8.9e-113 engB D Necessary for normal cell division and for the maintenance of normal septation
NECFGCCN_04887 8.8e-63 yihI S A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis
NECFGCCN_04888 1.5e-261 hemN 1.3.98.3 H Belongs to the anaerobic coproporphyrinogen-III oxidase family
NECFGCCN_04890 2.2e-268 glnG T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
NECFGCCN_04891 6.2e-196 glnL 2.7.13.3 T Signal transduction histidine kinase, nitrogen specific
NECFGCCN_04892 1.1e-275 glnA 5.4.4.3, 6.3.1.2 E glutamine synthetase
NECFGCCN_04893 0.0 typA T GTP-binding protein TypA
NECFGCCN_04894 7.4e-109 yihX 3.1.3.10 S hydrolase
NECFGCCN_04895 6.4e-138 rbn K UPF0761 membrane protein
NECFGCCN_04896 9.6e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NECFGCCN_04897 8.8e-184 yiiD K Putative thioesterase (yiiD_Cterm)
NECFGCCN_04898 3.8e-165 aes I Alpha beta hydrolase
NECFGCCN_04899 1.2e-36 yiiE K Ribbon-helix-helix protein, copG family
NECFGCCN_04900 3.2e-65 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
NECFGCCN_04901 4.4e-177 fdhE O Necessary for formate dehydrogenase activity
NECFGCCN_04902 5e-116 fdoI C formate dehydrogenase
NECFGCCN_04903 2.3e-183 fdoH C formate dehydrogenase
NECFGCCN_04904 1.3e-212 fdoG 1.17.1.9, 1.17.5.3 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_04905 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NECFGCCN_04906 4.1e-83 mutT 3.6.1.55 F Nudix family
NECFGCCN_04908 6.4e-19
NECFGCCN_04909 2.1e-114 ycaK 1.6.5.2 C Flavodoxin-like fold
NECFGCCN_04910 7.8e-88 MA20_25245 K Gnat family
NECFGCCN_04911 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NECFGCCN_04913 9.6e-164 S CAAX amino terminal protease family protein
NECFGCCN_04914 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NECFGCCN_04915 3.3e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_04916 1.7e-17 XK27_00735
NECFGCCN_04917 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NECFGCCN_04918 3.9e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECFGCCN_04919 9.8e-10 O ADP-ribosylglycohydrolase
NECFGCCN_04920 5.6e-62 paaI Q protein possibly involved in aromatic compounds catabolism
NECFGCCN_04921 3.5e-61 ycaO O OsmC-like protein
NECFGCCN_04922 5.1e-77
NECFGCCN_04923 2e-122 S ABC-2 family transporter protein
NECFGCCN_04924 2.6e-11 L Belongs to the 'phage' integrase family
NECFGCCN_04925 0.0 S Phosphatase
NECFGCCN_04926 3.1e-77 znuC P ATPases associated with a variety of cellular activities
NECFGCCN_04927 6e-112 znuB P ABC 3 transport family
NECFGCCN_04928 3e-120 3.2.1.78 GH26 P Zinc-uptake complex component A periplasmic
NECFGCCN_04929 2e-177 zinT S amine dehydrogenase activity
NECFGCCN_04931 8.9e-191 E Glycine D-amino acid oxidases (Deaminating)
NECFGCCN_04932 5.9e-31
NECFGCCN_04933 3.1e-176 hemB 4.2.1.24 H Belongs to the ALAD family
NECFGCCN_04934 1.4e-229 pyrC 3.5.2.3 F Amidohydrolase family
NECFGCCN_04935 4.5e-59 S Succinylglutamate desuccinylase / Aspartoacylase family
NECFGCCN_04936 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NECFGCCN_04937 6.8e-122 psaA P Belongs to the bacterial solute-binding protein 9 family
NECFGCCN_04938 9.8e-96 sitB P ATPases associated with a variety of cellular activities
NECFGCCN_04939 5.6e-126 sitC P ABC 3 transport family
NECFGCCN_04940 2.6e-104 sitD P Iron transport protein, inner membrane component SitD
NECFGCCN_04941 4.7e-66 I Protein of unknown function (DUF1460)
NECFGCCN_04942 3.3e-134 queD 1.1.1.42 H COG0720 6-pyruvoyl-tetrahydropterin synthase
NECFGCCN_04943 2.3e-96 ccmM S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NECFGCCN_04944 4.4e-116 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NECFGCCN_04946 9e-184 cioB 1.10.3.14 C oxidase subunit
NECFGCCN_04947 3.8e-265 cioA 1.10.3.14 C oxidase, subunit
NECFGCCN_04949 2.3e-262 ydcR 2.7.7.65 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_04950 5.3e-225 ydcS E Spermidine putrescine ABC transporter substrate-binding protein
NECFGCCN_04951 6.1e-180 ydcT 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NECFGCCN_04952 1.1e-162 ydcU P ABC transporter (Permease
NECFGCCN_04953 1e-142 ydcV P ABC transporter (permease)
NECFGCCN_04954 9.2e-267 prr 1.2.1.19, 1.2.1.3 C belongs to the aldehyde dehydrogenase family
NECFGCCN_04956 8.7e-11
NECFGCCN_04958 2.2e-21 ydcX S Toxin GhoT_OrtT
NECFGCCN_04959 1.4e-125 S Alpha beta hydrolase
NECFGCCN_04960 1.4e-259 vdh 1.2.1.28 C belongs to the aldehyde dehydrogenase family
NECFGCCN_04961 0.0 dppA E ABC-Type Dipeptide Transport System Periplasmic Component
NECFGCCN_04962 7e-31 ydcY S Protein of unknown function (DUF2526)
NECFGCCN_04963 3.1e-67 ydcZ S membrane
NECFGCCN_04964 5.2e-95 yncA 2.3.1.183 M acetyltransferase
NECFGCCN_04965 3.4e-103 K transcriptional regulator
NECFGCCN_04966 6e-199 yncB S nadp-dependent
NECFGCCN_04967 1.9e-175 rihA G Belongs to the IUNH family
NECFGCCN_04968 7.1e-44 yiiS S Protein of unknown function (DUF406)
NECFGCCN_04969 2.2e-251 nfdA_2 S metal-dependent hydrolase with the TIM-barrel fold
NECFGCCN_04970 0.0 yncD P receptor
NECFGCCN_04971 7.3e-168 yncE S DNA binding
NECFGCCN_04972 3.5e-32 ygdR S (Lipo)protein
NECFGCCN_04973 6.9e-270 ansP E Involved in the transporte of L-asparagine
NECFGCCN_04974 1.2e-155 dmlR_3 K Transcriptional regulator
NECFGCCN_04975 1.3e-99 adk 2.7.4.3 F adenylate kinase
NECFGCCN_04976 8.4e-182 ytmO C Luciferase Family
NECFGCCN_04977 2.4e-206 yxeP 3.5.1.32 S amidohydrolase
NECFGCCN_04978 6.9e-253 moxC C monooxygenase
NECFGCCN_04979 2e-169 fliY_4 ET ABC transporter substrate-binding protein
NECFGCCN_04980 3.8e-90 K N-acetyltransferase
NECFGCCN_04981 3.9e-157 P amino acid ABC transporter
NECFGCCN_04982 4.5e-12 gluA 3.6.3.21 E (ABC) transporter
NECFGCCN_04983 2.6e-10
NECFGCCN_04986 6.3e-57 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NECFGCCN_04988 3.4e-141 hdfR K Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon
NECFGCCN_04989 2.2e-46 yifE S protein conserved in bacteria
NECFGCCN_04990 1.5e-158 comM O ATPase with chaperone activity
NECFGCCN_04991 4.8e-100 comM O ATPase with chaperone activity
NECFGCCN_04992 0.0 ilvG 2.2.1.6 H acetolactate synthase
NECFGCCN_04993 3.2e-37 ilvM 2.2.1.6 S acetolactate synthase
NECFGCCN_04994 1.3e-176 ilvE 2.6.1.21, 2.6.1.42 E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NECFGCCN_04995 0.0 ilvD 4.2.1.9 EG Belongs to the IlvD Edd family
NECFGCCN_04996 1.1e-294 ilvA 4.3.1.15, 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NECFGCCN_04997 7.5e-166 ilvY K transcriptional regulator
NECFGCCN_04998 5.7e-280 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NECFGCCN_04999 3.8e-47 ppiC 5.2.1.8 G peptidylprolyl isomerase
NECFGCCN_05000 2.3e-44 ppiC 5.2.1.8 G PPIC-type PPIASE domain
NECFGCCN_05001 0.0 rep 3.6.4.12 L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
NECFGCCN_05002 5.5e-119 S Protein of unknown function (DUF554)
NECFGCCN_05003 4.7e-193 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
NECFGCCN_05004 4.1e-167 K Transcriptional regulator
NECFGCCN_05005 1.5e-259 gppA 3.6.1.11, 3.6.1.40 FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities
NECFGCCN_05006 1.1e-239 rhlB 3.6.4.13 JKL DEAD-box RNA helicase involved in
NECFGCCN_05007 4.7e-57 trxA O Belongs to the thioredoxin family
NECFGCCN_05008 8.2e-235 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NECFGCCN_05009 4.6e-181 wecA 2.7.8.33, 2.7.8.35, 5.1.3.14 M Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55)
NECFGCCN_05010 1.9e-189 wzzE M Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
NECFGCCN_05011 1.5e-208 wecB 5.1.3.14 M Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues
NECFGCCN_05012 5.7e-236 wecC 1.1.1.336 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NECFGCCN_05013 3.1e-203 rffG 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NECFGCCN_05014 2.5e-169 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NECFGCCN_05015 3.5e-115 wecD 2.3.1.210 K Catalyzes the acetylation of dTDP-fucosamine (dTDP-4- amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA)
NECFGCCN_05016 1.2e-197 wecE 2.6.1.59 E Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate
NECFGCCN_05017 4.6e-222 wzxE U Mediates the transbilayer movement of Und-PP-GlcNAc- ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA)
NECFGCCN_05018 7.5e-205 rffT 2.4.1.325 GT56 C Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis
NECFGCCN_05019 1.5e-250 wzyE S Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units
NECFGCCN_05020 7.1e-138 rffM 2.4.1.180, 2.4.1.187 GT26 M Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis
NECFGCCN_05021 4.2e-256 yifK E 'involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine'
NECFGCCN_05024 6.8e-178 yegQ O Peptidase U32
NECFGCCN_05025 7.5e-252 yegQ O Peptidase U32
NECFGCCN_05026 7.5e-52 S CHY zinc finger
NECFGCCN_05027 7.9e-86 bioY S biotin synthase
NECFGCCN_05029 1.1e-33 XK27_12190 S protein conserved in bacteria
NECFGCCN_05030 2.4e-232 mntH P H( )-stimulated, divalent metal cation uptake system
NECFGCCN_05031 4.8e-11
NECFGCCN_05032 3.1e-13
NECFGCCN_05033 5.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NECFGCCN_05034 4.3e-32 M LysM domain
NECFGCCN_05035 1.1e-18 V Glucan-binding protein C
NECFGCCN_05037 7.1e-83 S RES domain protein
NECFGCCN_05038 1.6e-76 S Protein of unknown function (DUF2384)
NECFGCCN_05039 2.8e-23 umuC 2.7.7.7 L Binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)
NECFGCCN_05040 7.7e-10 fecB P Periplasmic binding protein
NECFGCCN_05041 0.0 fecA P receptor
NECFGCCN_05042 5.5e-84 fecR PT Fe2 -dicitrate sensor, membrane component
NECFGCCN_05043 8.7e-82 fecI K Belongs to the sigma-70 factor family. ECF subfamily
NECFGCCN_05044 1e-94 yedA EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_05045 6.9e-107 wrbA 1.6.5.2 S Belongs to the WrbA family
NECFGCCN_05046 2e-35 yccJ S YccJ-like protein
NECFGCCN_05047 1.9e-236 agp 3.1.3.10 S Acid phosphatase
NECFGCCN_05048 3e-78 K transcriptional regulator
NECFGCCN_05049 7.9e-135 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_05050 3.3e-30
NECFGCCN_05051 9.4e-11
NECFGCCN_05052 4.5e-258 puuP E Amino Acid
NECFGCCN_05054 7.5e-120 puuA 6.3.1.11, 6.3.1.2 E glutamine synthetase
NECFGCCN_05055 6.2e-169 yeiH S Membrane
NECFGCCN_05056 9.3e-127 mur1 3.4.17.14, 3.5.1.28 NU muramidase
NECFGCCN_05057 6.1e-93 XK27_05000 S metal cluster binding
NECFGCCN_05058 0.0 V ABC transporter (permease)
NECFGCCN_05059 7.1e-133 macB2 V ABC transporter, ATP-binding protein
NECFGCCN_05060 6.5e-166 T Histidine kinase
NECFGCCN_05061 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
NECFGCCN_05062 1.1e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NECFGCCN_05063 1.9e-137 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
NECFGCCN_05064 3.8e-44 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NECFGCCN_05065 1.9e-267 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NECFGCCN_05066 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NECFGCCN_05067 1.3e-54 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
NECFGCCN_05068 2.7e-193 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_05070 4.1e-107 dtpB U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_05071 2e-135 rsmJ 2.1.1.242 J Specifically methylates the guanosine in position 1516 of 16S rRNA
NECFGCCN_05072 0.0 prlC 3.4.15.5, 3.4.24.70 E oligopeptidase
NECFGCCN_05073 2.6e-228 phoC I phosphoesterase, PA-phosphatase
NECFGCCN_05074 3.2e-158 rlmJ 2.1.1.266 H Specifically methylates the adenine in position 2030 of 23S rRNA
NECFGCCN_05075 1.2e-263 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NECFGCCN_05076 6.7e-121 gst8 2.5.1.18 O Glutathione S-Transferase
NECFGCCN_05077 9.9e-206 eutG 1.1.1.1, 4.3.3.7 C alcohol dehydrogenase
NECFGCCN_05078 0.0 treF 3.2.1.28 GH37 G Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NECFGCCN_05079 3.3e-100 J Acetyltransferases, including N-acetylases of ribosomal proteins
NECFGCCN_05080 8.4e-134 IQ short-chain dehydrogenase
NECFGCCN_05081 8.9e-167 yhjC K transcriptional regulator
NECFGCCN_05082 7.5e-186 yhjD S Membrane
NECFGCCN_05083 3e-235 yhjE EGP Major facilitator superfamily
NECFGCCN_05084 0.0 yhjG M protein involved in outer membrane biogenesis
NECFGCCN_05085 4.7e-171 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NECFGCCN_05086 1.9e-283 yhjJ S Peptidase, M16
NECFGCCN_05087 1e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NECFGCCN_05088 0.0 yhjK T the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation
NECFGCCN_05089 0.0 M Cellulose synthase
NECFGCCN_05090 2.3e-212 bcsZ 3.2.1.4 GH5,GH8,GH9 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
NECFGCCN_05091 0.0 bcsB M Cellulose synthase
NECFGCCN_05092 0.0 bcsA 2.4.1.12 GT2 M Cellulose synthase
NECFGCCN_05093 3.7e-131 yhjQ D Cellulose synthase
NECFGCCN_05094 5.8e-28 yhjR S Cellulose biosynthesis protein BcsR
NECFGCCN_05095 4.5e-291 bcsE S cellulose biosynthesis protein BcsE
NECFGCCN_05096 1.5e-26 bcsF S Cellulose biosynthesis protein BcsF
NECFGCCN_05097 2.6e-281 kbaA 2.7.8.42, 2.7.8.43 S cellulose synthase operon protein YhjU
NECFGCCN_05098 1.6e-193 celC 3.2.1.4 GH8 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
NECFGCCN_05099 3.6e-57 bcsD S cellulose synthase
NECFGCCN_05100 1.7e-11 bcsD S cellulose synthase
NECFGCCN_05101 0.0 M Cellulose synthase
NECFGCCN_05102 0.0 bcsB NU cellulose synthase
NECFGCCN_05103 0.0 bcsA 2.4.1.12 GT2 M Cellulose synthase
NECFGCCN_05104 1.5e-144 yhjQ D cellulose synthase operon protein YhjQ
NECFGCCN_05105 2.4e-42 S Cellulose biosynthesis protein BcsO
NECFGCCN_05106 1.7e-190 dppF P Belongs to the ABC transporter superfamily
NECFGCCN_05107 1.7e-182 dppD 3.6.3.24 P Belongs to the ABC transporter superfamily
NECFGCCN_05108 2.1e-131 dppC P PFAM binding-protein-dependent transport systems inner membrane component
NECFGCCN_05109 1.7e-185 dppB P PFAM binding-protein-dependent transport systems inner membrane component
NECFGCCN_05110 0.0 dppA E ABC-Type Dipeptide Transport System Periplasmic Component
NECFGCCN_05111 8.5e-108 dtpA U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_05112 1.3e-105 gst 2.5.1.18 O Belongs to the GST superfamily
NECFGCCN_05113 3.5e-160 pdxY 2.7.1.35 H Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NECFGCCN_05114 2.1e-246 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NECFGCCN_05115 9e-124 pdxH 1.4.3.5 H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
NECFGCCN_05116 3.1e-54 mliC S membrane-bound lysozyme inhibitor of c-type lysozyme
NECFGCCN_05117 1.1e-211 anmK 2.7.1.170, 4.2.1.126 F Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NECFGCCN_05118 1.3e-52 slyB M Outer Membrane Lipoprotein
NECFGCCN_05119 7.3e-197 T Diguanylate cyclase
NECFGCCN_05120 6.8e-72 slyA K Transcription regulator that can specifically activate or repress expression of target genes
NECFGCCN_05121 4.3e-36 ydhI S Protein of unknown function (DUF1656)
NECFGCCN_05122 1.9e-137 ydhJ V Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_05123 0.0 ydhK S Fusaric acid resistance protein
NECFGCCN_05124 1.3e-90 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NECFGCCN_05125 1.8e-167 ydhF S Aldo Keto reductase
NECFGCCN_05126 4.2e-39 ydhL S Fe-S protein
NECFGCCN_05127 4.5e-106 nemR K transcriptional regulator
NECFGCCN_05128 2.6e-205 nemA C nadh flavin
NECFGCCN_05129 2.4e-71 gloA 4.4.1.5 E Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione
NECFGCCN_05130 2.4e-121 rnt L Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis
NECFGCCN_05131 3.3e-61 grxD C Belongs to the glutaredoxin family. Monothiol subfamily
NECFGCCN_05132 2.2e-122 ydhO 3.2.1.14, 3.4.17.13 GH18 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NECFGCCN_05133 5.3e-73 K Transcriptional regulator
NECFGCCN_05134 1.4e-109 sodB 1.15.1.1, 3.1.11.6 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NECFGCCN_05135 2.7e-36
NECFGCCN_05136 1.3e-45 S Protein of unknown function with HXXEE motif
NECFGCCN_05137 7.7e-64 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECFGCCN_05138 1.1e-60
NECFGCCN_05139 1.5e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NECFGCCN_05141 6.2e-51 spd F DNA RNA non-specific endonuclease
NECFGCCN_05142 5.6e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NECFGCCN_05143 4.2e-253 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NECFGCCN_05144 2.3e-113 lolA M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NECFGCCN_05145 0.0 ftsK D PFAM cell divisionFtsK SpoIIIE
NECFGCCN_05146 2.5e-65 copY K Copper transport repressor, CopY TcrY family
NECFGCCN_05147 5.8e-230 ycdB P peroxidase
NECFGCCN_05148 5.1e-143 ycdO P periplasmic lipoprotein involved in iron transport
NECFGCCN_05149 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NECFGCCN_05150 6.5e-19 agrA KT phosphorelay signal transduction system
NECFGCCN_05151 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NECFGCCN_05152 1.1e-143 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NECFGCCN_05153 6.7e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NECFGCCN_05154 1.8e-44
NECFGCCN_05155 4.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
NECFGCCN_05156 2.1e-48 G COG0477 Permeases of the major facilitator superfamily
NECFGCCN_05157 2e-163 vllY 1.13.11.27 E 4-hydroxyphenylpyruvate dioxygenase
NECFGCCN_05158 4.5e-52 K transcriptional regulator, PadR family
NECFGCCN_05159 3.4e-58 XK27_06920 S Protein of unknown function (DUF1700)
NECFGCCN_05160 2.7e-101 S Putative adhesin
NECFGCCN_05161 1.2e-138 XK27_06930 V domain protein
NECFGCCN_05162 7.6e-69 cpoB 3.5.1.28 D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NECFGCCN_05163 3.6e-75 pal M Belongs to the ompA family
NECFGCCN_05164 3e-155 tolB U involved in the tonB-independent uptake of proteins
NECFGCCN_05165 8.7e-46 tolA M Membrane protein involved in colicin uptake
NECFGCCN_05166 1.2e-68 tolR U biopolymer transport protein
NECFGCCN_05167 2.9e-117 tolQ U MotA TolQ ExbB proton channel
NECFGCCN_05168 1.6e-67 ybgC S Thioesterase
NECFGCCN_05169 2.8e-45 ybgE S cyd operon protein YbgE
NECFGCCN_05170 3.1e-11 ybgT 1.10.3.14 S Cyd operon protein YbgT
NECFGCCN_05171 5e-215 cydB 1.10.3.14 C cytochrome d ubiquinol oxidase, subunit
NECFGCCN_05172 1.1e-294 cydA 1.10.3.14 C oxidase, subunit
NECFGCCN_05173 8.6e-159 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NECFGCCN_05174 1.2e-216 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NECFGCCN_05175 2.4e-207 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NECFGCCN_05176 0.0 sucA 1.2.4.2, 4.1.1.71 C Dehydrogenase E1 component
NECFGCCN_05177 3.7e-139 sdhB 1.3.5.1, 1.3.5.4 C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NECFGCCN_05178 0.0 sdhA 1.3.5.1, 1.3.5.4 C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily
NECFGCCN_05179 3.3e-53 sdhD C Succinate dehydrogenase hydrophobic membrane anchor subunit
NECFGCCN_05180 1.2e-65 sdhC C succinate dehydrogenase
NECFGCCN_05181 7e-250 gltA 2.3.3.1 C Belongs to the citrate synthase family
NECFGCCN_05182 2e-138 nei 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates
NECFGCCN_05183 6.9e-113 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NECFGCCN_05184 4.3e-178 S Protein of unknown function (DUF979)
NECFGCCN_05185 4.5e-129 S Protein of unknown function (DUF969)
NECFGCCN_05186 8.5e-131 ybgL S Belongs to the UPF0271 (lamB) family
NECFGCCN_05187 1.4e-178 ybgK 3.5.1.54, 6.3.4.6 E Allophanate hydrolase subunit 2
NECFGCCN_05188 2.4e-121 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NECFGCCN_05189 5e-139 ybgI 3.5.4.16 S metal-binding protein
NECFGCCN_05190 1.6e-123 dtpD U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_05191 2.3e-23 dtpD U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_05192 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NECFGCCN_05193 2.9e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NECFGCCN_05194 7.6e-184 pelG M Putative exopolysaccharide Exporter (EPS-E)
NECFGCCN_05195 1e-273 pelF GT4 M Domain of unknown function (DUF3492)
NECFGCCN_05196 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
NECFGCCN_05197 2.7e-147
NECFGCCN_05198 3.7e-206 5.1.3.2 GM Psort location CytoplasmicMembrane, score
NECFGCCN_05199 7e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NECFGCCN_05200 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NECFGCCN_05201 2.1e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NECFGCCN_05202 2.4e-101 yjbK S Adenylate cyclase
NECFGCCN_05203 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NECFGCCN_05204 9.8e-208 iscS 2.8.1.7 E Cysteine desulfurase
NECFGCCN_05205 8.2e-60 XK27_04120 S Putative amino acid metabolism
NECFGCCN_05206 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NECFGCCN_05207 4.4e-129 puuD T peptidase C26
NECFGCCN_05208 9e-119 radC E Belongs to the UPF0758 family
NECFGCCN_05209 2.3e-53
NECFGCCN_05210 4.2e-198 yhhJ V ABC-type multidrug transport system, permease component
NECFGCCN_05211 0.0 rbbA V (ABC) transporter
NECFGCCN_05212 5.3e-134 yhiI M Secretion protein
NECFGCCN_05213 2e-266 dosC 2.7.7.65 T Diguanylate cyclase
NECFGCCN_05214 1.9e-181 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NECFGCCN_05215 1.6e-169 lsrB_2 G (ABC) transporter
NECFGCCN_05216 1.1e-233 3.6.3.17 G ABC transporter
NECFGCCN_05217 5.3e-157 U Branched-chain amino acid transport system / permease component
NECFGCCN_05218 3.2e-154 U Branched-chain amino acid transport system / permease component
NECFGCCN_05219 1.7e-153 nqo1 1.6.5.2 S NADPH dehydrogenase
NECFGCCN_05220 6.7e-154 syrM1 K transcriptional regulator
NECFGCCN_05221 1.3e-75 fosB 2.5.1.18 E Glutathione transferase
NECFGCCN_05222 5e-10 S Protein of unknown function (DUF4059)
NECFGCCN_05223 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NECFGCCN_05224 2.5e-92 rsmD 2.1.1.171 L Methyltransferase
NECFGCCN_05225 5e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NECFGCCN_05226 6e-186 ylbL T Belongs to the peptidase S16 family
NECFGCCN_05227 1e-181 yhcC S radical SAM protein
NECFGCCN_05228 9.4e-95 ytqB 2.1.1.176 J (SAM)-dependent
NECFGCCN_05230 0.0 yjcE P NhaP-type Na H and K H antiporters
NECFGCCN_05231 1.6e-79 L reverse transcriptase
NECFGCCN_05232 2.8e-122 ydiJ C Fad linked oxidase
NECFGCCN_05233 3.2e-71 menI 3.1.2.28 Q Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA)
NECFGCCN_05234 7e-37 yeaQ S transglycosylase associated protein
NECFGCCN_05235 2.4e-292 yfhM P Large extracellular alpha-helical protein
NECFGCCN_05236 0.0 pbpC 2.4.1.129 GT51 M penicillin-binding protein 1C
NECFGCCN_05237 8.5e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NECFGCCN_05238 7.9e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NECFGCCN_05239 8.3e-100 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NECFGCCN_05240 4.9e-38 S oxidoreductase
NECFGCCN_05241 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
NECFGCCN_05242 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NECFGCCN_05243 0.0 clpE O Belongs to the ClpA ClpB family
NECFGCCN_05244 2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NECFGCCN_05245 1e-34 ykuJ S protein conserved in bacteria
NECFGCCN_05246 1.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NECFGCCN_05247 9.3e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_05248 1.6e-77 feoA P FeoA domain protein
NECFGCCN_05249 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NECFGCCN_05250 8.6e-08
NECFGCCN_05251 6.1e-148 I Alpha/beta hydrolase family
NECFGCCN_05252 3.1e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NECFGCCN_05253 1.6e-155 yjjU I esterase of the alpha-beta hydrolase superfamily
NECFGCCN_05254 1.1e-125 yjjV L Deoxyribonuclease
NECFGCCN_05255 3.5e-209 nupX F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NECFGCCN_05256 6.8e-139 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NECFGCCN_05257 1.3e-238 deoA 2.4.2.2, 2.4.2.4 F The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NECFGCCN_05258 6.1e-243 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NECFGCCN_05259 2.9e-132 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NECFGCCN_05260 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NECFGCCN_05261 1.2e-25 metB 2.5.1.48, 4.4.1.8 E cystathionine
NECFGCCN_05262 2.6e-155 metB 2.5.1.48, 4.4.1.8 E cystathionine
NECFGCCN_05263 3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NECFGCCN_05264 1.1e-40 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
NECFGCCN_05265 2.6e-147 1.13.11.2 S glyoxalase
NECFGCCN_05266 1.6e-97 dppB_1 P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_05267 1.1e-161 P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_05268 8e-157 oppD 3.6.3.24 EP (ABC) transporter
NECFGCCN_05269 1.1e-136 3.6.3.24 EP (ABC) transporter
NECFGCCN_05270 9.5e-169 yegS 2.7.1.107 I the in vivo substrate is
NECFGCCN_05271 3.2e-269 yegQ O protease
NECFGCCN_05272 2.3e-133 K response regulator
NECFGCCN_05273 7.3e-259 T PhoQ Sensor
NECFGCCN_05274 5.7e-253 mdtD EGP Major facilitator superfamily
NECFGCCN_05275 0.0 mdtC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_05276 3.4e-62 yhaI J Protein of unknown function (DUF805)
NECFGCCN_05277 1.1e-162 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NECFGCCN_05278 3e-78 K hmm pf08876
NECFGCCN_05279 1.2e-118 yqfA K protein, Hemolysin III
NECFGCCN_05280 6.7e-198 S Protein of unknown function (DUF3114)
NECFGCCN_05281 7.7e-86 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NECFGCCN_05282 5.1e-202 rpsA 1.17.7.4 J ribosomal protein S1
NECFGCCN_05285 6.4e-39 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
NECFGCCN_05286 2e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NECFGCCN_05287 3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NECFGCCN_05288 8.7e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NECFGCCN_05289 3.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NECFGCCN_05290 4.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NECFGCCN_05291 7.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NECFGCCN_05292 5.1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NECFGCCN_05294 8.1e-51 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NECFGCCN_05296 0.0 S dextransucrase activity
NECFGCCN_05297 2.1e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_05298 3e-40 L COG1943 Transposase and inactivated derivatives
NECFGCCN_05301 4.7e-33 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NECFGCCN_05302 7.6e-23 fruR K transcriptional
NECFGCCN_05303 3e-44 M domain protein
NECFGCCN_05304 3.8e-212 salK 2.7.13.3 T Histidine kinase
NECFGCCN_05305 3e-102 salR K helix_turn_helix, Lux Regulon
NECFGCCN_05306 2.1e-86 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
NECFGCCN_05307 1.9e-116 gltJ P ABC transporter (Permease
NECFGCCN_05308 1.1e-110 tcyB_2 P ABC transporter (permease)
NECFGCCN_05309 2e-19 L transposase activity
NECFGCCN_05310 1.9e-13
NECFGCCN_05311 3.2e-121 glnQ 3.6.3.21 E abc transporter atp-binding protein
NECFGCCN_05312 2.6e-124 btuF P (ABC) transporter
NECFGCCN_05313 9.3e-43 L Integrase core domain
NECFGCCN_05314 4.2e-83 L Integrase core domain
NECFGCCN_05315 2.2e-212 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NECFGCCN_05317 2e-132 agrA KT Response regulator of the LytR AlgR family
NECFGCCN_05318 2.8e-192 S cobalamin synthesis protein
NECFGCCN_05319 5.1e-256 lamB G Maltoporin (phage lambda and maltose receptor)
NECFGCCN_05320 0.0 imd 3.2.1.94 GH27 S cellulase activity
NECFGCCN_05321 1.4e-60 M NlpC/P60 family
NECFGCCN_05322 5.7e-64
NECFGCCN_05323 3.2e-75
NECFGCCN_05325 1.8e-84 M tape measure protein
NECFGCCN_05327 2.6e-07
NECFGCCN_05328 1.8e-80 K BRO family, N-terminal domain
NECFGCCN_05329 4.5e-78 ant K BRO family, N-terminal domain
NECFGCCN_05331 1.5e-110 K Helix-turn-helix domain
NECFGCCN_05332 8.2e-31
NECFGCCN_05333 5.9e-34
NECFGCCN_05334 5.1e-43 gepA S Protein of unknown function (DUF4065)
NECFGCCN_05335 1.1e-119
NECFGCCN_05336 6e-132 N domain, Protein
NECFGCCN_05337 3.5e-64
NECFGCCN_05338 1.9e-51
NECFGCCN_05339 7.7e-61
NECFGCCN_05340 8.6e-26
NECFGCCN_05341 1.1e-62
NECFGCCN_05342 2.5e-30
NECFGCCN_05343 2.6e-186 S Linocin_M18 bacteriocin protein
NECFGCCN_05344 7.8e-68
NECFGCCN_05345 1.7e-225 S protein conserved in bacteria
NECFGCCN_05347 3.1e-159 S head morphogenesis protein, SPP1 gp7
NECFGCCN_05348 6.1e-266 S Protein of unknown function (DUF1073)
NECFGCCN_05349 3.8e-292 S Terminase
NECFGCCN_05350 2.3e-82 xtmA L terminase, small subunit
NECFGCCN_05351 1.6e-10 S Uncharacterized small protein (DUF2158)
NECFGCCN_05353 1.3e-44
NECFGCCN_05354 7.7e-88 S Phage lysozyme
NECFGCCN_05355 2.1e-32 essD S Bacteriophage P21 holin S
NECFGCCN_05360 5.2e-92
NECFGCCN_05361 5e-16 ylcG
NECFGCCN_05362 7.4e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NECFGCCN_05363 1e-47 S phage protein
NECFGCCN_05364 4.4e-09 S NINE Protein
NECFGCCN_05365 1.6e-106 S Protein of unknown function (DUF1367)
NECFGCCN_05367 2e-23 D Protein of unknown function (DUF551)
NECFGCCN_05368 1.1e-15
NECFGCCN_05370 1.6e-28
NECFGCCN_05371 8.4e-107 yhdJ 2.1.1.72 L DNA methylase
NECFGCCN_05372 2.3e-57 S exonuclease activity
NECFGCCN_05373 1.3e-13
NECFGCCN_05374 2.8e-16
NECFGCCN_05375 8.7e-78 S DNA replication initiation
NECFGCCN_05376 1.7e-43 K Helix-turn-helix domain
NECFGCCN_05377 3.3e-30 S Bacteriophage CII protein
NECFGCCN_05378 1.1e-28 S Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT
NECFGCCN_05379 1.2e-88 K Peptidase S24-like
NECFGCCN_05381 3.2e-10 S Predicted membrane protein (DUF2335)
NECFGCCN_05382 2.2e-25
NECFGCCN_05385 8.1e-31
NECFGCCN_05386 2.4e-41
NECFGCCN_05388 3.6e-48
NECFGCCN_05389 5.4e-54 L YqaJ-like viral recombinase domain
NECFGCCN_05390 1.4e-69
NECFGCCN_05391 2.7e-120 KT Belongs to the MT-A70-like family
NECFGCCN_05392 6.8e-28
NECFGCCN_05393 2.2e-273 ycjX S COG3106 Predicted ATPase
NECFGCCN_05394 2.9e-31 pspD S Phage Shock Protein
NECFGCCN_05395 7.9e-58 pspC KT phage shock protein C
NECFGCCN_05396 1.4e-33 pspB S Phage shock protein B
NECFGCCN_05397 4.7e-64 pspA KT Phage shock protein A
NECFGCCN_05398 2.1e-177 pspF K transcriptional activator
NECFGCCN_05399 2.9e-225 norB G Quinolone resistance protein
NECFGCCN_05400 1.9e-222 3.5.1.32 S amidohydrolase
NECFGCCN_05401 0.0 K helix_turn_helix, arabinose operon control protein
NECFGCCN_05402 9.9e-152 K transcriptional
NECFGCCN_05403 7.4e-153 GM Nad-dependent epimerase dehydratase
NECFGCCN_05404 0.0 sapA E ABC transporter substrate-binding protein
NECFGCCN_05405 1.8e-173 sapB P peptide transport system, permease
NECFGCCN_05406 4.7e-160 sapC V peptide transport system, permease
NECFGCCN_05407 1e-192 sapD P ATPase activity
NECFGCCN_05408 2.9e-148 sapF P ATPase activity
NECFGCCN_05409 1.2e-242 fcy21 U Belongs to the purine-cytosine permease (2.A.39) family
NECFGCCN_05410 1.5e-81 ves S protein conserved in bacteria
NECFGCCN_05411 1.7e-142 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NECFGCCN_05412 1.7e-146 yciW S protein conserved in bacteria
NECFGCCN_05413 0.0 rnb 3.1.13.1 J Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NECFGCCN_05414 2.2e-24 yciZ S Belongs to the UPF0509 family
NECFGCCN_05415 1.6e-132 yciT K transcriptional regulator
NECFGCCN_05416 7.6e-27 osmB M Lipoprotein
NECFGCCN_05417 1.6e-52 yciH J Translation Initiation Factor
NECFGCCN_05418 5.3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NECFGCCN_05419 9.3e-217 lapB G Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NECFGCCN_05420 3.9e-45 lapA S Involved in the assembly of lipopolysaccharide (LPS)
NECFGCCN_05421 3.3e-138 pgpB 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidylglycerophosphatase
NECFGCCN_05422 7.9e-111 ribA 3.5.4.25 F Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NECFGCCN_05423 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NECFGCCN_05424 6.6e-23
NECFGCCN_05425 3.6e-182 cysB K transcriptional regulator
NECFGCCN_05426 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NECFGCCN_05427 2.3e-40 yciN S Protein of unknown function (DUF2498)
NECFGCCN_05428 2.2e-180 sohB OU peptidase
NECFGCCN_05429 1.5e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_05430 1.4e-107 cobO 2.5.1.17 H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
NECFGCCN_05431 1.7e-165 rluB 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECFGCCN_05432 1.1e-84 K LysR substrate binding domain
NECFGCCN_05433 5.2e-98 yijE EG EamA-like transporter family
NECFGCCN_05434 1.9e-115 yciO 2.7.7.87 J Belongs to the SUA5 family
NECFGCCN_05435 7.5e-163 trpH 3.1.3.97 S Metal-dependent phosphoesterases (PHP family)
NECFGCCN_05436 7.2e-289 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NECFGCCN_05437 3.3e-289 trpD 2.4.2.18, 2.6.1.85, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NECFGCCN_05438 7.4e-172 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
NECFGCCN_05439 3.4e-59 K sequence-specific DNA binding
NECFGCCN_05440 3.3e-98 S Carbohydrate-binding domain-containing protein Cthe_2159
NECFGCCN_05441 2.8e-177 XK27_08075 M glycosyl transferase family 2
NECFGCCN_05442 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NECFGCCN_05443 1.6e-20 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NECFGCCN_05444 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NECFGCCN_05446 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NECFGCCN_05447 1.1e-164 metF 1.5.1.20 E reductase
NECFGCCN_05448 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NECFGCCN_05449 1.7e-91 panT S ECF transporter, substrate-specific component
NECFGCCN_05450 1.7e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NECFGCCN_05451 1.9e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NECFGCCN_05452 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NECFGCCN_05453 5.1e-187 L Transposase
NECFGCCN_05454 6e-41 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NECFGCCN_05455 9.6e-62 yjqA S Bacterial PH domain
NECFGCCN_05456 1.8e-151 corA P CorA-like protein
NECFGCCN_05457 1.7e-253 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NECFGCCN_05458 1e-41 yazA L endonuclease containing a URI domain
NECFGCCN_05459 1.2e-127 yabB 2.1.1.223 L Methyltransferase
NECFGCCN_05460 4.6e-142 nodB3 G deacetylase
NECFGCCN_05461 1.1e-141 plsC 2.3.1.51 I Acyltransferase
NECFGCCN_05462 1.4e-87 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NECFGCCN_05463 0.0 comEC S Competence protein ComEC
NECFGCCN_05464 2.3e-229 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NECFGCCN_05465 3.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NECFGCCN_05466 7.3e-231 ytoI K transcriptional regulator containing CBS domains
NECFGCCN_05467 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NECFGCCN_05468 5.7e-150 rbn E Belongs to the UPF0761 family
NECFGCCN_05469 2.8e-85 ccl S cog cog4708
NECFGCCN_05470 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NECFGCCN_05471 2.4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NECFGCCN_05474 9.4e-170 yfjR K regulation of single-species biofilm formation
NECFGCCN_05476 1.2e-69 S QueT transporter
NECFGCCN_05477 5.9e-157 xth 3.1.11.2 L exodeoxyribonuclease III
NECFGCCN_05479 8.2e-194 S dextransucrase activity
NECFGCCN_05480 1.5e-141 S ABC-2 family transporter protein
NECFGCCN_05481 4.2e-90 S ABC-2 family transporter protein
NECFGCCN_05482 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NECFGCCN_05483 2.7e-23
NECFGCCN_05484 7.6e-90 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NECFGCCN_05485 3.9e-145 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NECFGCCN_05486 2.9e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NECFGCCN_05487 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NECFGCCN_05488 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NECFGCCN_05489 3.4e-144 licT K antiterminator
NECFGCCN_05490 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NECFGCCN_05491 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NECFGCCN_05492 1.7e-12 2.7.13.3 T GHKL domain
NECFGCCN_05493 1.7e-58 2.7.13.3 T GHKL domain
NECFGCCN_05494 4.7e-23 L COG3547 Transposase and inactivated derivatives
NECFGCCN_05495 1.2e-24 yrpB 1.13.12.16, 1.3.1.9 S 2-nitropropane dioxygenase
NECFGCCN_05496 1.8e-248 3.5.1.28 NU GBS Bsp-like repeat
NECFGCCN_05497 5e-125 yieP K transcriptional regulator
NECFGCCN_05498 3.6e-247 hsrA EGP Major facilitator superfamily
NECFGCCN_05499 7.4e-183 rbsR K Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression
NECFGCCN_05500 1.4e-151 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NECFGCCN_05501 2.9e-154 rbsB G Periplasmic
NECFGCCN_05502 2.8e-150 rbsC P Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_05503 3.2e-278 rbsA 3.6.3.17 P import. Responsible for energy coupling to the transport system
NECFGCCN_05504 2.3e-69 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NECFGCCN_05505 0.0 kup P transport of potassium into the cell
NECFGCCN_05506 1.1e-281 ravA S Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone
NECFGCCN_05507 8.1e-271 viaA S VWA domain protein interacting with AAA ATPase
NECFGCCN_05508 5e-187 asnA 6.3.1.1 E aspartate--ammonia ligase
NECFGCCN_05509 1.5e-77 asnC K transcriptional
NECFGCCN_05510 1e-75 mioC C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NECFGCCN_05511 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NECFGCCN_05512 1.1e-110 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA
NECFGCCN_05513 2.1e-56 atpI C Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
NECFGCCN_05514 5.4e-147 atpB C it plays a direct role in the translocation of protons across the membrane
NECFGCCN_05515 1.7e-32 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NECFGCCN_05516 4.1e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NECFGCCN_05517 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NECFGCCN_05518 1.2e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NECFGCCN_05519 2.4e-153 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NECFGCCN_05520 1.2e-258 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NECFGCCN_05521 3.1e-69 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NECFGCCN_05522 1.2e-236 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NECFGCCN_05523 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NECFGCCN_05524 1.7e-193 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
NECFGCCN_05525 1.2e-169 pstC P probably responsible for the translocation of the substrate across the membrane
NECFGCCN_05526 2.9e-154 pstA P phosphate transport system permease
NECFGCCN_05527 1.1e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NECFGCCN_05528 4.9e-131 phoU P Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions
NECFGCCN_05529 0.0 bglH M PFAM porin LamB type
NECFGCCN_05530 1.5e-214 yieL P Belongs to the glycosyl hydrolase 13 family
NECFGCCN_05531 3.3e-124 nagB 3.1.1.31, 3.5.99.6 G glucosamine-6-phosphate deaminase activity
NECFGCCN_05532 2.2e-122 yieH S HAD-superfamily hydrolase subfamily IA, variant 3
NECFGCCN_05533 1.1e-229 yieG S permease
NECFGCCN_05534 1.8e-101 yieF S NAD(P)H-dependent FMN reductase
NECFGCCN_05535 3.1e-125 yieE 2.7.8.7 H Phosphopantetheinyl transferase
NECFGCCN_05536 7e-186 yidZ K HTH-type transcriptional regulator YidZ
NECFGCCN_05537 7e-196 mdtL EGP Major facilitator Superfamily
NECFGCCN_05538 2.2e-75 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECFGCCN_05539 6.8e-251 mnmE J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NECFGCCN_05540 2.3e-298 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
NECFGCCN_05541 2.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NECFGCCN_05542 5.5e-264 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NECFGCCN_05543 2e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NECFGCCN_05544 3.2e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NECFGCCN_05545 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NECFGCCN_05546 3.5e-146 yidA S member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins
NECFGCCN_05547 3.8e-193
NECFGCCN_05548 1.7e-215 M Outer membrane protein protective antigen OMA87
NECFGCCN_05549 3e-122 dgoR K FCD domain
NECFGCCN_05550 2.7e-160 dgoK 2.7.1.58 G 2-keto-3-deoxy-galactonokinase
NECFGCCN_05551 6.2e-111 dgoA 4.1.2.14, 4.1.2.21, 4.1.3.42 G KDPG and KHG aldolase
NECFGCCN_05552 1.5e-227 dgoD 4.2.1.6 H Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate
NECFGCCN_05553 3.6e-246 dgoT G Major facilitator superfamily
NECFGCCN_05554 1.5e-241 yidR U Biopolymer transporter Tol
NECFGCCN_05555 2.4e-53 yidQ S (Lipo)protein
NECFGCCN_05556 2.5e-71 ibpA O Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent
NECFGCCN_05557 2.9e-75 ibpB O Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK DnaJ GrpE. Its activity is ATP- independent
NECFGCCN_05558 6.1e-114 dinD S DNA-damage-inducible protein d
NECFGCCN_05559 7.6e-289 yidE U transport protein
NECFGCCN_05560 6.3e-134 yidP K transcriptional regulator
NECFGCCN_05561 4.3e-305 glvC 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system
NECFGCCN_05562 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G 6-phospho-alpha-glucosidase
NECFGCCN_05563 4.2e-48 yidH S Membrane
NECFGCCN_05564 5e-60 yidG S Membrane
NECFGCCN_05565 1.9e-78 yidF K radical SAM
NECFGCCN_05566 2.1e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NECFGCCN_05567 2.1e-228 dsdX EG Gluconate
NECFGCCN_05568 1.5e-172 dsdC K transcriptional regulator
NECFGCCN_05569 8.8e-215 emrD EGP Major facilitator Superfamily
NECFGCCN_05570 2.7e-141 EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_05571 1.7e-81 K Acetyltransferase (GNAT) domain
NECFGCCN_05574 0.0 ilvB 2.2.1.6 H acetolactate synthase
NECFGCCN_05575 1.6e-48 ilvN 2.2.1.6 E acetolactate synthase
NECFGCCN_05576 1.9e-104 uhpA K response regulator
NECFGCCN_05577 2.5e-275 uhpB 2.7.13.3 T Histidine kinase
NECFGCCN_05578 2.4e-253 uhpC G transporter
NECFGCCN_05579 4.5e-258 uhpT G PFAM Major facilitator superfamily
NECFGCCN_05580 1.3e-78 yicN S Protein of unknown function (DUF1198)
NECFGCCN_05581 4.3e-30 radC E Belongs to the UPF0758 family
NECFGCCN_05586 8.6e-09 S ERF superfamily
NECFGCCN_05587 7.1e-30 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NECFGCCN_05588 7.6e-38 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NECFGCCN_05589 9.1e-223 amiA E ABC transporter, substrate-binding protein, family 5
NECFGCCN_05590 4.6e-118 V Type III restriction enzyme, res subunit
NECFGCCN_05594 1.1e-175 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NECFGCCN_05595 5.1e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_05596 1.1e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_05597 5.6e-115 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NECFGCCN_05598 2.8e-260 cbs 2.5.1.47, 4.2.1.22 E Belongs to the cysteine synthase cystathionine beta- synthase family
NECFGCCN_05599 3.5e-216 metC 2.5.1.48, 4.4.1.1, 4.4.1.8 E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide
NECFGCCN_05600 2.2e-165 K transcriptional regulator
NECFGCCN_05601 2.1e-103 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_05602 1.1e-51
NECFGCCN_05603 2e-15
NECFGCCN_05605 1.6e-219 lysN EK Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_05606 0.0 gsp 3.5.1.78, 6.3.1.8 E Glutathionylspermidine synthase
NECFGCCN_05607 9.9e-108 5.3.4.1 O Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NECFGCCN_05608 3.1e-169 yghU O Belongs to the GST superfamily
NECFGCCN_05609 2.4e-49 yghW S response to butan-1-ol
NECFGCCN_05610 9.4e-169 yghX 3.1.1.45 Q Dienelactone hydrolase
NECFGCCN_05611 1.5e-83 yqhA S UPF0114 protein
NECFGCCN_05612 4.6e-232 G Belongs to the glycosyl hydrolase 43 family
NECFGCCN_05613 2.7e-242 yicJ G COG2211 Na melibiose symporter and related transporters
NECFGCCN_05614 6.3e-62 exbD U Biopolymer transport protein, ExbD
NECFGCCN_05615 8.4e-123 exbB U tonB-system energizer ExbB
NECFGCCN_05616 3.8e-07
NECFGCCN_05617 7.2e-225 metC 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E cystathionine beta-lyase
NECFGCCN_05618 3.3e-118 yghB S Pfam SNARE associated Golgi protein
NECFGCCN_05619 1.1e-161 yqhC K transcriptional regulator
NECFGCCN_05620 4.9e-218 yqhD C alcohol dehydrogenase
NECFGCCN_05621 1.2e-157 dkgA 1.1.1.346 S reductase
NECFGCCN_05622 1.7e-85 M Acetyltransferase (GNAT) domain
NECFGCCN_05623 0.0 ygiQ C UPF0313 protein
NECFGCCN_05624 9.7e-277 ftsP D Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress
NECFGCCN_05625 4e-125 plsC 2.3.1.51, 3.1.3.3 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NECFGCCN_05626 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NECFGCCN_05627 9.2e-169 ygiV K transcriptional regulator
NECFGCCN_05628 1.5e-54 ygiW S Bacterial OB fold (BOF) protein
NECFGCCN_05629 1.5e-118 K response regulator
NECFGCCN_05630 1.1e-234 qseC 2.7.13.3 T Histidine kinase
NECFGCCN_05631 1.1e-109 mdaB S modulator of drug activity B
NECFGCCN_05632 1.5e-52 ygiN S monooxygenase
NECFGCCN_05633 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NECFGCCN_05634 1.1e-104 yqiA S esterase
NECFGCCN_05635 4.6e-162 cpdA 2.1.2.2, 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NECFGCCN_05636 7.6e-76 yqiB S protein conserved in bacteria
NECFGCCN_05637 1.2e-112 nudF 3.6.1.13 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NECFGCCN_05638 7.1e-238 tolC MU type I secretion outer membrane protein, TolC
NECFGCCN_05639 4.8e-117 ygiB S Belongs to the UPF0441 family
NECFGCCN_05640 2.3e-228 ygiC 3.5.1.78, 6.3.1.8 E Glutathionylspermidine synthase
NECFGCCN_05641 2.7e-151 ygiD 1.13.11.8 S dioxygenase
NECFGCCN_05642 5.2e-115 zupT P Mediates zinc uptake. May also transport other divalent cations
NECFGCCN_05643 2.8e-117 ribB 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NECFGCCN_05644 1.1e-38 yqiC S protein conserved in bacteria
NECFGCCN_05645 1.7e-30 glgS S positive regulation of cellular carbohydrate metabolic process
NECFGCCN_05646 3.5e-266 hldE 2.7.1.167, 2.7.7.70 H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NECFGCCN_05647 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NECFGCCN_05648 4.5e-236 ygiF 3.6.1.25 S Adenylate cyclase
NECFGCCN_05649 1.4e-110 ygiM T sh3 domain protein
NECFGCCN_05650 8.6e-237 cca 2.7.7.19, 2.7.7.72 F Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases
NECFGCCN_05651 1.1e-142 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NECFGCCN_05652 2.1e-64 folB 1.13.11.81, 4.1.2.25, 5.1.99.7, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NECFGCCN_05653 1.4e-110 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NECFGCCN_05655 7.9e-154 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NECFGCCN_05656 4e-47 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NECFGCCN_05657 1.9e-55 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NECFGCCN_05658 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NECFGCCN_05659 2e-72 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NECFGCCN_05660 6.7e-125 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NECFGCCN_05661 7.8e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NECFGCCN_05662 7.8e-299 F Belongs to the purine-cytosine permease (2.A.39) family
NECFGCCN_05663 3.2e-189 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NECFGCCN_05664 1.6e-29 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NECFGCCN_05665 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NECFGCCN_05666 0.0 rpoD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NECFGCCN_05667 1.5e-91 mug 3.2.2.28, 6.3.3.2 L Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells
NECFGCCN_05669 3.3e-40
NECFGCCN_05670 4.5e-09 hdeB M Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins
NECFGCCN_05671 4.9e-108 evgA 3.1.4.52 K response regulator
NECFGCCN_05672 0.0 evgS 2.7.13.3 T PhoQ Sensor
NECFGCCN_05673 2.1e-98 yfdX S YfdX protein
NECFGCCN_05674 2.5e-98 hdeD S Acid-resistance membrane protein
NECFGCCN_05675 2.7e-51 hdeB M Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins
NECFGCCN_05676 4.2e-144 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NECFGCCN_05677 0.0 O glycerol dehydratase
NECFGCCN_05678 1.1e-71 pduE 4.2.1.28, 4.2.1.30 Q Dehydratase Small Subunit
NECFGCCN_05679 7.7e-103 dhaC 4.2.1.28, 4.2.1.30 Q dehydratase, medium subunit
NECFGCCN_05680 2.3e-311 dhaB 4.2.1.28, 4.2.1.30 E Dehydratase large subunit
NECFGCCN_05681 8.9e-69 pduO S protein possibly involved in utilization of glycolate and propanediol
NECFGCCN_05682 8.4e-218 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
NECFGCCN_05683 2e-61 S Dehydratase medium subunit
NECFGCCN_05684 6.1e-91 MMAB 2.5.1.17 S adenosyltransferase
NECFGCCN_05685 0.0 dhaR KQ Positively regulates the dhaKLM operon from a sigma-70 promoter
NECFGCCN_05686 5.5e-203 gldA 1.1.1.6 C glycerol dehydrogenase
NECFGCCN_05687 3.5e-202 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
NECFGCCN_05688 6.8e-113 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dihydroxyacetone kinase
NECFGCCN_05689 2.5e-248 dhaM 2.7.1.121, 2.7.1.202, 2.7.3.9 G Belongs to the PEP-utilizing enzyme family
NECFGCCN_05690 2.2e-296 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
NECFGCCN_05691 5.2e-147 yqjH 1.16.1.9 P Siderophore-interacting protein
NECFGCCN_05692 5.2e-93 yqjI K transcriptional regulator
NECFGCCN_05693 7.3e-261 patA 2.6.1.11, 2.6.1.17, 2.6.1.82 H Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine
NECFGCCN_05694 3.2e-49 lsrG 5.3.1.32 S Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD)
NECFGCCN_05695 3.3e-166 lsrF 2.3.1.245, 4.1.2.13 H Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA
NECFGCCN_05696 2e-183 lsrB G Periplasmic binding protein domain
NECFGCCN_05697 2.1e-172 lsrD P Branched-chain amino acid transport system / permease component
NECFGCCN_05698 1.2e-178 lsrC U Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_05699 6e-269 lsrA 3.6.3.17 P Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system
NECFGCCN_05700 2e-172 lsrR K transcriptional regulator
NECFGCCN_05701 3.3e-305 lsrK 2.7.1.17, 2.7.1.189, 2.7.1.5 G Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3- dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position
NECFGCCN_05702 0.0 fadH 1.3.1.34 C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NECFGCCN_05703 1.1e-214 rlmG 2.1.1.172, 2.1.1.174 J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA
NECFGCCN_05704 9.7e-92 S B3 4 domain
NECFGCCN_05705 4.2e-72 puuR_1 K Helix-turn-helix domain
NECFGCCN_05706 6.2e-85 ygjP S WLM domain
NECFGCCN_05707 9.1e-181 ygjR S oxidoreductase
NECFGCCN_05708 9.6e-167 alx P membrane protein, terc
NECFGCCN_05709 3.2e-215 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NECFGCCN_05710 6e-97 ygjV S Membrane
NECFGCCN_05711 4.7e-290 uxaA 4.2.1.7 G Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate
NECFGCCN_05712 6.7e-278 uxaC 5.3.1.12 G glucuronate isomerase
NECFGCCN_05713 1.6e-241 exuT G Major facilitator superfamily
NECFGCCN_05714 1.6e-143 exuR K Transcriptional
NECFGCCN_05715 2.5e-118 yqjA S Inner membrane protein yqjA
NECFGCCN_05716 1.2e-64 mzrA S Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR
NECFGCCN_05717 9.3e-38 yqjC S Protein of unknown function (DUF1090)
NECFGCCN_05718 1.2e-41 yqjD S Membrane protein YqjD
NECFGCCN_05719 2.8e-56 yqjE S Membrane
NECFGCCN_05720 2.2e-45 yqjK S Membrane
NECFGCCN_05721 2.5e-65 yqjF S membrane
NECFGCCN_05722 7.7e-188 yqjG 1.8.5.7, 2.5.1.18 O Glutathione S-Transferase
NECFGCCN_05723 6e-69 yhaH S Membrane
NECFGCCN_05724 3.5e-163 yhaJ K transcriptional regulator
NECFGCCN_05725 1.6e-123 yhaK S Belongs to the pirin family
NECFGCCN_05726 5.4e-17 yhaL
NECFGCCN_05727 1.8e-53 NPTU COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein
NECFGCCN_05730 4.9e-110 yhfC S Putative membrane peptidase family (DUF2324)
NECFGCCN_05731 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
NECFGCCN_05732 1.4e-14 S integral membrane protein
NECFGCCN_05733 3.4e-25 mccF V LD-carboxypeptidase
NECFGCCN_05734 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NECFGCCN_05735 2.1e-23
NECFGCCN_05736 2.8e-251 P 50S ribosome-binding GTPase
NECFGCCN_05737 7.2e-190 P N,N-dimethylaniline monooxygenase activity
NECFGCCN_05738 3.1e-22 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NECFGCCN_05739 2.5e-123 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NECFGCCN_05742 4.3e-85 yfjR K regulation of single-species biofilm formation
NECFGCCN_05743 8.4e-23
NECFGCCN_05744 2.4e-130 recQ 3.6.4.12 L DNA helicase
NECFGCCN_05745 1.6e-168 pldA 3.1.1.32, 3.1.1.4 M Phospholipase
NECFGCCN_05746 4.7e-79 yigI Q protein possibly involved in aromatic compounds catabolism
NECFGCCN_05747 2.8e-165 rarD S Rard protein
NECFGCCN_05748 2.5e-175 corA P Mediates influx of magnesium ions
NECFGCCN_05749 0.0 uvrD 3.6.4.12 L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
NECFGCCN_05750 7.4e-132 yigB 3.1.3.10, 3.1.3.102, 3.1.3.104 S Hydrolase
NECFGCCN_05751 2.2e-165 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NECFGCCN_05752 1.2e-126 yigA S protein conserved in bacteria
NECFGCCN_05753 4.1e-158 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NECFGCCN_05754 2.3e-31 yifL N Prokaryotic lipoprotein-attachment site
NECFGCCN_05755 3.2e-58 cyaY 1.16.3.1 P Belongs to the frataxin family
NECFGCCN_05756 0.0 cyaA 4.6.1.1 F Adenylate cyclase
NECFGCCN_05757 3.3e-167 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NECFGCCN_05758 6.5e-131 hemD 2.1.1.107, 2.5.1.61, 4.2.1.75 H Uroporphyrinogen-III synthase
NECFGCCN_05759 1.6e-176 hemX 2.1.1.107, 4.2.1.75 H enzyme of heme biosynthesis
NECFGCCN_05760 1.6e-219 hemY H enzyme of heme biosynthesis
NECFGCCN_05761 1.7e-07
NECFGCCN_05762 9.7e-132 pip 1.11.1.10 S Alpha beta hydrolase
NECFGCCN_05763 7.9e-191 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NECFGCCN_05764 1e-35 6.3.2.4 M D-ala D-ala ligase C-terminus
NECFGCCN_05766 6.8e-78 yjaB K Acetyltransferase
NECFGCCN_05767 3.8e-181 metAS 2.3.1.46 E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine
NECFGCCN_05768 0.0 aceB 2.3.3.9 C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NECFGCCN_05769 1e-248 aceA 4.1.3.1 C Isocitrate lyase
NECFGCCN_05770 0.0 aceK 2.7.11.5 F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation
NECFGCCN_05771 3.5e-149 iclR K transcriptional regulator
NECFGCCN_05772 0.0 metH 2.1.1.13 E methionine synthase
NECFGCCN_05773 1.9e-284 yjbB P Na Pi-Cotransporter
NECFGCCN_05774 1.2e-143 aroE 1.1.1.25 E shikimate
NECFGCCN_05775 1.3e-245 sorE E L-sorbose 1-phosphate reductase
NECFGCCN_05776 5e-148 sorM G IID component
NECFGCCN_05777 5.2e-134 sorA G pts system
NECFGCCN_05778 2.7e-88 sorB 2.7.1.191, 2.7.1.206 G iib component
NECFGCCN_05779 1.4e-71 sorF 2.7.1.191, 2.7.1.206 G IIa component
NECFGCCN_05780 9.5e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_05781 2.2e-179 sorC K transcriptional regulator
NECFGCCN_05782 6.9e-164 rluF 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECFGCCN_05783 2.1e-39 yjbD S YjbD family (DUF3811)
NECFGCCN_05784 4.9e-160 yocS S Bile acid sodium symporter
NECFGCCN_05785 1.9e-242 lysC 1.1.1.3, 2.7.2.4, 4.1.1.20 E Belongs to the aspartokinase family
NECFGCCN_05786 0.0 pgi 5.3.1.9 G Belongs to the GPI family
NECFGCCN_05787 5.7e-77 2.3.1.79 S UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase
NECFGCCN_05788 4.4e-62 2.3.1.57 K acetyltransferase
NECFGCCN_05789 9.9e-59 tdcF 3.5.99.10 J PFAM Endoribonuclease L-PSP
NECFGCCN_05790 7.3e-47 S Branched-chain amino acid transport protein (AzlD)
NECFGCCN_05791 5.7e-111 E AzlC protein
NECFGCCN_05792 1.4e-34 yhaM S Belongs to the UPF0597 family
NECFGCCN_05793 1.3e-43 yhaM S Belongs to the UPF0597 family
NECFGCCN_05794 6.3e-106 yhaM S Belongs to the UPF0597 family
NECFGCCN_05795 3.4e-65 psiE S Protein PsiE homolog
NECFGCCN_05796 1.2e-160 malG P transport
NECFGCCN_05797 6.4e-290 malF P transport
NECFGCCN_05798 4.5e-18 3.1.4.4 I phospholipase D activity
NECFGCCN_05799 1.4e-133 dnaQ 2.7.7.7, 3.1.26.4 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NECFGCCN_05800 1.6e-87 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NECFGCCN_05801 4.8e-139 yafS Q Methyl-transferase
NECFGCCN_05802 8.6e-147 gloB 3.1.2.6 S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NECFGCCN_05803 3.7e-257 mltD M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NECFGCCN_05804 1.5e-135 yafE Q methyltransferase
NECFGCCN_05805 1.2e-149 yafD S UPF0294 protein
NECFGCCN_05806 2.3e-202 ytbD EGP Major facilitator Superfamily
NECFGCCN_05807 7.3e-161 yafC K Transcriptional regulator
NECFGCCN_05808 1.4e-142 dkgB 1.1.1.346 S reductase
NECFGCCN_05809 1.4e-119 potA 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NECFGCCN_05810 1.5e-150 potB P ABC-type spermidine putrescine transport system, permease component I
NECFGCCN_05811 1.9e-133 potC P ABC-type spermidine putrescine transport system, permease component II
NECFGCCN_05812 2.9e-201 potD P Required for the activity of the bacterial periplasmic transport system of putrescine
NECFGCCN_05813 0.0 1.2.1.5 C COG1012 NAD-dependent aldehyde dehydrogenases
NECFGCCN_05814 3.4e-310 6.2.1.44 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NECFGCCN_05815 4.2e-261 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type
NECFGCCN_05816 1.2e-104 arcR T Winged helix-turn-helix DNA binding
NECFGCCN_05817 5.6e-79 S YfaZ precursor
NECFGCCN_05818 1.6e-59
NECFGCCN_05820 2.1e-49 secG U Preprotein translocase, subunit SecG
NECFGCCN_05821 2.7e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NECFGCCN_05822 6.5e-151 folP 2.5.1.15 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NECFGCCN_05823 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NECFGCCN_05824 1e-113 ftsJ 2.1.1.166 J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NECFGCCN_05825 4.8e-49 yhbY J CRS1 / YhbY (CRM) domain
NECFGCCN_05826 1.4e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NECFGCCN_05827 4.8e-239 dacB 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NECFGCCN_05828 1.7e-194 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NECFGCCN_05829 1.9e-170 yhbE EG Permeases of the drug metabolite transporter (DMT) superfamily
NECFGCCN_05830 8.2e-41 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NECFGCCN_05831 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NECFGCCN_05832 4.6e-177 ispB 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NECFGCCN_05833 2e-45 sfsB K transcriptional regulator
NECFGCCN_05834 6.3e-235 murA 2.5.1.7 M Belongs to the EPSP synthase family. MurA subfamily
NECFGCCN_05835 2.8e-41 yrbA K Belongs to the BolA IbaG family
NECFGCCN_05836 4.1e-41 mlaB S NTP binding protein (Contains STAS domain)
NECFGCCN_05837 8.1e-114 mlaC Q ABC-type transport system involved in resistance to organic solvents auxiliary component
NECFGCCN_05838 3.5e-97 mlaD Q ABC-type transport system involved in resistance to organic solvents periplasmic component
NECFGCCN_05839 3.9e-134 mlaE Q COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
NECFGCCN_05840 3.7e-148 mlaF Q (ABC) transporter
NECFGCCN_05841 2.5e-162 yrbG P antiporter
NECFGCCN_05842 2.9e-182 kdsD 5.3.1.13 M Arabinose 5-phosphate isomerase
NECFGCCN_05843 3.8e-99 kdsC 3.1.3.45 S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NECFGCCN_05844 1.4e-101 lptC S Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA
NECFGCCN_05845 6.1e-94 lptA T Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NECFGCCN_05846 2.4e-130 lptB S abc transporter atp-binding protein
NECFGCCN_05847 7.6e-253 rpoN K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NECFGCCN_05848 9.5e-46 hpf J sigma (54) modulation protein
NECFGCCN_05849 6.3e-82 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202 G PTS IIA-like nitrogen-regulatory protein PtsN
NECFGCCN_05850 1.9e-158 rapZ S Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS
NECFGCCN_05851 6.7e-41 ptsO 2.7.1.121, 2.7.1.202, 2.7.3.9 H PTS HPr component phosphorylation site
NECFGCCN_05852 2.8e-131 mtgA 2.4.1.129, 3.4.16.4 GT51 M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NECFGCCN_05853 2.1e-109 elbB Q Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NECFGCCN_05854 0.0 arcB 2.7.13.3 T PhoQ Sensor
NECFGCCN_05855 2.5e-208 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NECFGCCN_05856 1.1e-186 rspB 1.1.1.380 C Dehydrogenase
NECFGCCN_05857 1.6e-222 G Major facilitator superfamily
NECFGCCN_05858 1e-173 yhcC S radical SAM protein
NECFGCCN_05859 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E Glutamate synthase
NECFGCCN_05860 2.7e-279 gltD 1.4.1.13, 1.4.1.14 C Glutamate synthase
NECFGCCN_05861 4e-114 nanE 2.7.1.60, 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NECFGCCN_05862 5.5e-78 sspB S stringent starvation protein b
NECFGCCN_05863 1.3e-116 sspA O stringent starvation protein A
NECFGCCN_05864 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NECFGCCN_05865 3.4e-91 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NECFGCCN_05866 1.3e-210 zapE D Reduces the stability of FtsZ polymers in the presence of ATP
NECFGCCN_05867 3.3e-65 yhcB S Cytochrome D ubiquinol oxidase, subunit
NECFGCCN_05868 2.2e-241 degQ 1.3.1.74, 3.4.21.107 M Belongs to the peptidase S1C family
NECFGCCN_05869 8.5e-193 degS 3.4.21.107 M Belongs to the peptidase S1C family
NECFGCCN_05870 1.9e-167 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NECFGCCN_05871 3.4e-77 argR K Regulates arginine biosynthesis genes
NECFGCCN_05872 1.3e-38 yhcN S Protein of unknown function (DUF1471)
NECFGCCN_05873 7.5e-37 bhsA_1 S Protein of unknown function (DUF1471)
NECFGCCN_05874 1.1e-43 yhcO K inhibitor
NECFGCCN_05875 0.0 aaeB U Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell
NECFGCCN_05876 4.4e-161 aaeA V P-hydroxybenzoic acid efflux pump subunit AaeA
NECFGCCN_05877 2.6e-29 aaeX S Protein of unknown function (DUF1656)
NECFGCCN_05878 1.7e-168 aaeR K Transcriptional regulator
NECFGCCN_05879 3.5e-266 tldD S 'responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase
NECFGCCN_05880 0.0 yhdP D Membrane
NECFGCCN_05881 4.2e-275 rng J Involved in the processing of the 5'-end of 16S rRNA
NECFGCCN_05882 3.6e-92 maf 2.1.1.190 D Maf-like protein
NECFGCCN_05883 3.7e-82 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NECFGCCN_05884 2.8e-177 mreC M Involved in formation and maintenance of cell shape
NECFGCCN_05885 2.3e-190 mreB D TIGRFAM Cell shape determining protein MreB Mrl
NECFGCCN_05886 0.0 csrD T GGDEF domain
NECFGCCN_05887 1.5e-194 msrP C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NECFGCCN_05888 4.9e-100 msrQ C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NECFGCCN_05889 1.5e-74 aroQ 3.4.13.9, 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NECFGCCN_05890 2.9e-60 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NECFGCCN_05891 5.1e-259 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NECFGCCN_05892 2e-36 yhdT S Membrane
NECFGCCN_05893 6.3e-223 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECFGCCN_05894 1.5e-166 prmA J Ribosomal protein L11 methyltransferase
NECFGCCN_05895 1.5e-183 dusB J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NECFGCCN_05896 4.4e-46 fis K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NECFGCCN_05897 1.5e-102 ttgR K acrEF envCD operon
NECFGCCN_05898 3.7e-202 acrE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NECFGCCN_05899 2.1e-90 acrF V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_05900 9.8e-52 acrF V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_05901 1.4e-90 acrF V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_05902 2.4e-51 zmpB M signal peptide protein, YSIRK family
NECFGCCN_05903 1.9e-36 zmpB M signal peptide protein, YSIRK family
NECFGCCN_05904 9.8e-83 zmpB M signal peptide protein, YSIRK family
NECFGCCN_05905 4.3e-56 zmpB M signal peptide protein, YSIRK family
NECFGCCN_05906 8.1e-34 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NECFGCCN_05907 2.5e-273 V ABC transporter
NECFGCCN_05908 6.1e-126 yeeN K transcriptional regulatory protein
NECFGCCN_05909 1.7e-46 yajC U protein transport
NECFGCCN_05910 5.9e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NECFGCCN_05911 4.6e-143 cdsA 2.7.7.41 S Belongs to the CDS family
NECFGCCN_05912 5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NECFGCCN_05913 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NECFGCCN_05914 0.0 WQ51_06230 S ABC transporter
NECFGCCN_05915 2.3e-142 cmpC S abc transporter atp-binding protein
NECFGCCN_05916 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NECFGCCN_05917 3.8e-285 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NECFGCCN_05918 2.5e-130 E Glyoxalase-like domain
NECFGCCN_05919 2.4e-170 alkR K Transcriptional regulator
NECFGCCN_05920 7.8e-147 nepI EGP Major facilitator Superfamily
NECFGCCN_05921 8.7e-28 K DNA-binding transcription factor activity
NECFGCCN_05922 6.2e-222 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NECFGCCN_05923 1.3e-20 S Antitoxin component of a toxin-antitoxin (TA) module
NECFGCCN_05924 4.5e-10 S Domain of unknown function (DUF3173)
NECFGCCN_05925 1.5e-219 L Belongs to the 'phage' integrase family
NECFGCCN_05926 1.4e-79 entS EGP Exports the siderophore enterobactin out of the cell
NECFGCCN_05928 4.1e-37 U domain, Protein
NECFGCCN_05929 2.3e-29
NECFGCCN_05930 7.5e-139 U Large exoproteins involved in heme utilization or adhesion
NECFGCCN_05931 1.1e-133 nahR K transcriptional regulator
NECFGCCN_05932 3.5e-247 EGP Major facilitator superfamily
NECFGCCN_05934 7.4e-116 nlpD DM COG0739 Membrane proteins related to metalloendopeptidases
NECFGCCN_05935 6.2e-102 idi 5.3.3.2 I Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NECFGCCN_05936 1e-22 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NECFGCCN_05937 6.2e-38 hpk9 2.7.13.3 T protein histidine kinase activity
NECFGCCN_05938 2.3e-224 fasC T protein histidine kinase activity
NECFGCCN_05939 8.2e-116 mtnB 3.1.3.87, 4.1.1.104, 4.1.2.17, 4.1.2.19, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NECFGCCN_05940 7.7e-36 codB F permease
NECFGCCN_05941 8.1e-120 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NECFGCCN_05942 0.0 3.5.1.28 M domain protein
NECFGCCN_05943 1.4e-136 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NECFGCCN_05944 2.7e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
NECFGCCN_05945 6.9e-66 rmaI K Transcriptional regulator, MarR family
NECFGCCN_05946 1.3e-238 EGP Major facilitator Superfamily
NECFGCCN_05947 7.8e-132 XK27_00785 S CAAX protease self-immunity
NECFGCCN_05948 7.4e-118 mleR K malolactic fermentation system
NECFGCCN_05949 1.2e-47 K Helix-turn-helix
NECFGCCN_05950 5e-309 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
NECFGCCN_05951 2.9e-160 mleP S Sodium Bile acid symporter family
NECFGCCN_05952 3.7e-99 NU Protein of unknown function (DUF3131)
NECFGCCN_05953 1.7e-108 G Protein of unknown function (DUF3131)
NECFGCCN_05954 1.2e-09 S NTF2 fold immunity protein
NECFGCCN_05955 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NECFGCCN_05956 4.3e-189 yeeE S Sulphur transport
NECFGCCN_05957 8.3e-37 yeeD O sulfur carrier activity
NECFGCCN_05958 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NECFGCCN_05959 5.1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NECFGCCN_05963 3.5e-157 rrmA 2.1.1.187 Q methyltransferase
NECFGCCN_05964 1.4e-128 S HAD hydrolase, family IA, variant
NECFGCCN_05965 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NECFGCCN_05966 2.2e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NECFGCCN_05967 1.2e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NECFGCCN_05968 4.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NECFGCCN_05969 1.9e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NECFGCCN_05970 7e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NECFGCCN_05971 3.3e-95 XK27_08585 S Psort location CytoplasmicMembrane, score
NECFGCCN_05972 4.8e-140 fnt P Formate nitrite transporter
NECFGCCN_05973 2.7e-21 XK27_09615 C reductase
NECFGCCN_05974 4.2e-52 XK27_09615 C reductase
NECFGCCN_05975 2.7e-35 XK27_09615 C reductase
NECFGCCN_05976 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
NECFGCCN_05977 1e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NECFGCCN_05978 4.4e-77 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NECFGCCN_05979 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NECFGCCN_05980 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
NECFGCCN_05981 3.5e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NECFGCCN_05982 1.2e-50 S Protein of unknown function (DUF3397)
NECFGCCN_05983 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NECFGCCN_05984 1.2e-118 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NECFGCCN_05986 3.3e-41 xisC L viral genome integration into host DNA
NECFGCCN_05988 3.6e-14
NECFGCCN_05990 5.4e-41 trsE S COG0433 Predicted ATPase
NECFGCCN_05991 5.8e-49 yczG K transcriptional regulator
NECFGCCN_05992 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NECFGCCN_05993 2.4e-245 4.1.3.27, 4.2.99.21, 5.4.4.2 EH chorismate binding enzyme
NECFGCCN_05994 8.1e-222 ybtX EGP Major Facilitator Superfamily
NECFGCCN_05995 0.0 ybtQ V ABC transporter transmembrane region
NECFGCCN_05996 0.0 ybtP V ABC transporter transmembrane region
NECFGCCN_05997 3.5e-185 ybtA K helix_turn_helix, arabinose operon control protein
NECFGCCN_05998 0.0 mbtB Q protein Irp2 TR Q9Z399 (EMBL AL031866) (2041 aa) fasta scores E() 0
NECFGCCN_05999 0.0 ppsE IQ PKS_KR
NECFGCCN_06000 0.0 ppsE IQ PKS_KR
NECFGCCN_06001 8.5e-220 pchG Q protein ybtU TR Q9Z3C6 (EMBL AL031866) (365 aa) fasta scores E()
NECFGCCN_06002 5.7e-157 irp4 3.1.2.21 Q Thioesterase domain
NECFGCCN_06003 2.4e-300 irp5 Q AMP-binding enzyme C-terminal domain
NECFGCCN_06004 0.0 fyuA P Receptor
NECFGCCN_06005 1e-101 yoqH M LysM domain
NECFGCCN_06006 1.9e-26 K Prophage CP4-57 regulatory protein (AlpA)
NECFGCCN_06008 4.3e-106 S Protein of unknown function (DUF2857)
NECFGCCN_06009 2.6e-25
NECFGCCN_06010 6.5e-96 virB1 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NECFGCCN_06011 3.7e-37 virB2 S TrbC/VIRB2 family
NECFGCCN_06012 0.0 lvhB4 U CagE, TrbE, VirB family, component of type IV transporter system
NECFGCCN_06013 5.9e-89 virB5 U type IV secretion
NECFGCCN_06014 6.8e-29
NECFGCCN_06015 1.1e-150 triE U TrbL/VirB6 plasmid conjugal transfer protein
NECFGCCN_06016 1.9e-15
NECFGCCN_06017 1.6e-120 virB8 U VirB8 protein
NECFGCCN_06018 3.2e-164 virB9 U Conjugal transfer protein
NECFGCCN_06019 5.1e-205 virB10 U Bacterial conjugation TrbI-like protein
NECFGCCN_06020 3.1e-200 virB11 NU Type II/IV secretion system protein
NECFGCCN_06021 2.3e-50 kikA S TrbM
NECFGCCN_06022 2.2e-48
NECFGCCN_06023 2.9e-273 sbcB 3.1.11.1 L Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
NECFGCCN_06024 1.1e-222 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NECFGCCN_06025 5.3e-86 sbmC L Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NECFGCCN_06026 1.3e-196 yeeA S Membrane
NECFGCCN_06027 7.1e-50 yeeX S Belongs to the UPF0265 family
NECFGCCN_06028 3.2e-122 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NECFGCCN_06029 4.3e-184 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NECFGCCN_06030 6.6e-212 3.3.1.1 H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NECFGCCN_06031 1.1e-125 T CBS-domain-containing membrane protein
NECFGCCN_06032 5.5e-65 S tautomerase
NECFGCCN_06033 2.2e-171 K transcriptional regulator
NECFGCCN_06034 7.9e-129 lipL 2.3.1.200, 2.3.1.204 H Lipoate-protein ligase
NECFGCCN_06035 6.3e-238 shiA EGP Major facilitator superfamily
NECFGCCN_06036 3.9e-63 S protein conserved in bacteria
NECFGCCN_06037 0.0 T Diguanylate cyclase
NECFGCCN_06038 6e-60 yeaR P Domain of unknown function (DUF1971)
NECFGCCN_06039 3e-43 yoaG S Domain of unknown function (DUF1869)
NECFGCCN_06040 9.4e-156 K transcriptional regulator
NECFGCCN_06041 3.8e-78
NECFGCCN_06042 8e-162 cpo 1.11.1.10 I Alpha beta hydrolase
NECFGCCN_06043 6.2e-182 T Diguanylate cyclase
NECFGCCN_06044 4.7e-194 KLT serine threonine protein kinase
NECFGCCN_06045 0.0 M family 8
NECFGCCN_06046 1.9e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NECFGCCN_06047 3.6e-288 asp1 S Accessory Sec system protein Asp1
NECFGCCN_06048 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NECFGCCN_06049 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NECFGCCN_06050 6.9e-212 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NECFGCCN_06051 3.9e-232 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NECFGCCN_06053 8.7e-60 divIC D Septum formation initiator
NECFGCCN_06054 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NECFGCCN_06055 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NECFGCCN_06056 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NECFGCCN_06057 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NECFGCCN_06058 3.2e-29 yyzM S Protein conserved in bacteria
NECFGCCN_06059 4.7e-193 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_06060 7.8e-134 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_06061 1e-113 S flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase
NECFGCCN_06062 2.3e-89 S 50S ribosomal protein L21
NECFGCCN_06063 1.8e-90 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NECFGCCN_06064 2.5e-161 ykgD K Transcriptional
NECFGCCN_06065 5.4e-147 metQ M Belongs to the nlpA lipoprotein family
NECFGCCN_06066 5.5e-158 EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_06067 3.1e-101 aspA 3.6.1.13 L Belongs to the Nudix hydrolase family
NECFGCCN_06068 1.3e-145 yddR S Zn-dependent hydrolases of the beta-lactamase fold
NECFGCCN_06069 7e-178 adpA K Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
NECFGCCN_06070 3.1e-203 yahK 1.1.1.1 S alcohol dehydrogenase
NECFGCCN_06071 1.4e-122 arcR T Winged helix-turn-helix DNA binding
NECFGCCN_06072 2.4e-44 S Antibiotic biosynthesis monooxygenase
NECFGCCN_06073 7.1e-181 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NECFGCCN_06074 4.9e-84 MA20_18690 S Belongs to the UPF0311 family
NECFGCCN_06076 4.2e-264 yicJ G COG2211 Na melibiose symporter and related transporters
NECFGCCN_06077 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
NECFGCCN_06078 9.4e-135 K Sugar isomerase
NECFGCCN_06079 9.2e-256 celF 3.2.1.86 GT4 G Glycoside hydrolase
NECFGCCN_06080 1.6e-296 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system
NECFGCCN_06081 0.0 yicH M AsmA Family
NECFGCCN_06082 4.2e-248 xanP F xanthine
NECFGCCN_06083 9.9e-206 gltS P Catalyzes the sodium-dependent transport of glutamate
NECFGCCN_06084 4e-18 S NADPH-dependent FMN reductase
NECFGCCN_06087 1e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NECFGCCN_06088 2.2e-79 yafM L Transposase IS200 like
NECFGCCN_06089 1.9e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NECFGCCN_06090 5.6e-144 XK27_02985 S overlaps another CDS with the same product name
NECFGCCN_06091 6.9e-147 supH S overlaps another CDS with the same product name
NECFGCCN_06092 2.1e-61 yvoA_1 K Transcriptional
NECFGCCN_06093 5.9e-118 skfE V abc transporter atp-binding protein
NECFGCCN_06094 9.3e-128 V Psort location CytoplasmicMembrane, score
NECFGCCN_06095 3.6e-171 oppF P Belongs to the ABC transporter superfamily
NECFGCCN_06096 1.3e-201 oppD P Belongs to the ABC transporter superfamily
NECFGCCN_06097 3.5e-166 amiD P ABC transporter (Permease
NECFGCCN_06098 9.3e-278 amiC P ABC transporter (Permease
NECFGCCN_06099 6.2e-306 amiA E ABC transporter, substrate-binding protein, family 5
NECFGCCN_06100 9.6e-104 amiA E ABC transporter, substrate-binding protein, family 5
NECFGCCN_06101 3.7e-72 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECFGCCN_06102 1.4e-303 hsdM 2.1.1.72 V type I restriction-modification system
NECFGCCN_06103 1.7e-42 K Helix-turn-helix domain
NECFGCCN_06104 4.7e-56 S Phage derived protein Gp49-like (DUF891)
NECFGCCN_06105 9.4e-39 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NECFGCCN_06106 1.4e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NECFGCCN_06107 2.1e-140 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NECFGCCN_06108 4.3e-43 yktA S Belongs to the UPF0223 family
NECFGCCN_06109 8e-49 T peptidase
NECFGCCN_06110 4.4e-133 E Alpha beta hydrolase
NECFGCCN_06112 1.1e-195 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NECFGCCN_06113 5.1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NECFGCCN_06114 2e-97 mip S hydroperoxide reductase activity
NECFGCCN_06115 1.1e-200 I acyl-CoA dehydrogenase
NECFGCCN_06116 5.3e-154 ydiA P C4-dicarboxylate transporter malic acid transport protein
NECFGCCN_06117 4.3e-08 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECFGCCN_06118 1.5e-113 S VIT family
NECFGCCN_06119 1e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
NECFGCCN_06120 2.7e-24
NECFGCCN_06121 1.2e-196 yceA S Belongs to the UPF0176 family
NECFGCCN_06122 7.7e-24 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NECFGCCN_06123 1.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NECFGCCN_06124 4.3e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NECFGCCN_06125 0.0 lmrA V abc transporter atp-binding protein
NECFGCCN_06126 2.2e-296 mdlB V abc transporter atp-binding protein
NECFGCCN_06127 1.7e-108 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NECFGCCN_06128 3.7e-17 yjdB S Domain of unknown function (DUF4767)
NECFGCCN_06129 1.1e-164 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NECFGCCN_06130 1.9e-90 eutG C alcohol dehydrogenase
NECFGCCN_06131 3.8e-182 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NECFGCCN_06132 1.9e-152 gst O Glutathione S-transferase
NECFGCCN_06133 2.5e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NECFGCCN_06134 7.6e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NECFGCCN_06135 4.2e-158 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NECFGCCN_06136 6.3e-11 zapB 2.1.1.80, 3.1.1.61 D Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA
NECFGCCN_06137 1.4e-189 sbp P sulfate ABC transporter
NECFGCCN_06138 5.8e-143 cdh 3.6.1.26 I CDP-diacylglycerol
NECFGCCN_06139 4.8e-238 P Citrate transporter
NECFGCCN_06140 3.7e-137 tpiA 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NECFGCCN_06141 5.5e-96 yiiQ S Protein of unknown function (DUF1454)
NECFGCCN_06142 1.2e-76 yiiR S Membrane
NECFGCCN_06143 2e-124 fpr 1.18.1.2, 1.19.1.1 C COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
NECFGCCN_06144 4.8e-185 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Fructose-1,6-bisphosphatase
NECFGCCN_06145 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NECFGCCN_06146 9.3e-124 trmH 2.1.1.185, 2.1.1.34 J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA
NECFGCCN_06147 0.0 spoT 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NECFGCCN_06148 1.6e-34 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NECFGCCN_06149 2.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NECFGCCN_06150 0.0 ligB 6.5.1.2 L Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction
NECFGCCN_06151 3e-105 yicG S Membrane
NECFGCCN_06152 2.6e-217 clcA_2 P Chloride channel
NECFGCCN_06153 4.5e-194 ada 2.1.1.63, 3.2.2.21 FL Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NECFGCCN_06154 1e-112 G COG2513 PEP phosphonomutase and related enzymes
NECFGCCN_06155 1e-151 yicC S Stress-induced protein
NECFGCCN_06156 3.3e-279 I Acyltransferase
NECFGCCN_06157 8.1e-158 V HlyD family secretion protein
NECFGCCN_06158 1.2e-38 ybhF V (ABC) transporter
NECFGCCN_06159 1.2e-115 ybhF V (ABC) transporter
NECFGCCN_06160 2.2e-191 ybhS V ABC-type multidrug transport system, permease component
NECFGCCN_06161 5.5e-127 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NECFGCCN_06162 2.8e-114 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NECFGCCN_06163 8.8e-171 gnl 3.1.1.17 G SMP-30/Gluconolaconase/LRE-like region
NECFGCCN_06164 2.5e-101 slmA D Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions
NECFGCCN_06165 5.5e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NECFGCCN_06166 7.2e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NECFGCCN_06167 2.7e-112 radC E Belongs to the UPF0758 family
NECFGCCN_06168 6.6e-37 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NECFGCCN_06169 1.9e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NECFGCCN_06170 4.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NECFGCCN_06171 3e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NECFGCCN_06172 1.5e-141 waaE GT2 M Glycosyl transferase
NECFGCCN_06173 3.8e-240 kdtA 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 M Transferase
NECFGCCN_06174 4.8e-190 wgaB 2.4.2.53 GT2 M Glycosyl transferase, family 2
NECFGCCN_06175 1.1e-203 rfaB 2.4.1.291 GT4 M glycosyl transferase group 1
NECFGCCN_06176 4.8e-218 rfaG GT4 M Catalyzes the addition of the first glucose residue to the LPS core
NECFGCCN_06177 3.4e-09
NECFGCCN_06178 5.6e-160 iolB 5.3.1.30 G 5-deoxyglucuronate isomerase
NECFGCCN_06179 2.1e-290 mmsA 1.2.1.18, 1.2.1.27 C Methylmalonate-semialdehyde dehydrogenase
NECFGCCN_06180 1.1e-150 iolI 5.3.99.11 G isomerase
NECFGCCN_06181 4.5e-280 yjgR S ATP-binding protein
NECFGCCN_06182 2.2e-196 lptG S permease
NECFGCCN_06183 2.9e-196 lptF S Permease
NECFGCCN_06184 3.7e-290 pepA 3.4.11.1, 3.4.11.23 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NECFGCCN_06185 1.3e-78 holC 2.7.7.7 L DNA polymerase III chi subunit
NECFGCCN_06186 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NECFGCCN_06187 6.4e-90 yjgM K Acetyltransferase
NECFGCCN_06188 2.6e-143 miaE FJ Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA
NECFGCCN_06189 4.3e-63 rraB S Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NECFGCCN_06190 1.7e-187 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NECFGCCN_06191 9.6e-77 tabA G Toxin-antitoxin biofilm protein TabA
NECFGCCN_06192 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NECFGCCN_06193 5.9e-82 pyrI 2.1.3.2 F Involved in allosteric regulation of aspartate carbamoyltransferase
NECFGCCN_06194 8.8e-63 ridA 3.5.99.10 J Endoribonuclease
NECFGCCN_06195 0.0 mgtA 3.6.3.2 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
NECFGCCN_06196 2.2e-171 treR K trehalose
NECFGCCN_06197 8.8e-262 treB 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NECFGCCN_06198 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NECFGCCN_06199 3.3e-242 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_06200 5.1e-240 celF 3.2.1.86 GT4 G Family 4 glycosyl hydrolase
NECFGCCN_06201 8.2e-40 celA 2.7.1.196, 2.7.1.205 G Phosphotransferase System
NECFGCCN_06202 3.7e-118 hexR K Transcriptional regulator
NECFGCCN_06203 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NECFGCCN_06204 5e-89 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NECFGCCN_06205 1.6e-45 relE DJ Cytotoxic translational repressor of toxin-antitoxin stability system
NECFGCCN_06206 2.2e-35 relB L bifunctional antitoxin of the RelE-RelB toxin-antitoxin system transcriptional repressor
NECFGCCN_06207 0.0 licR 2.7.1.197 GK transcriptional antiterminator
NECFGCCN_06208 1.7e-194 ykgB 3.1.1.31 G COG2706 3-carboxymuconate cyclase
NECFGCCN_06209 3.1e-133 4.1.2.14 S 2-dehydro-3-deoxyphosphooctonate aldolase
NECFGCCN_06210 4.8e-202 selA 2.9.1.1 E selenium transferase
NECFGCCN_06211 8.5e-207 dho 3.5.2.3 S Amidohydrolase family
NECFGCCN_06212 1.4e-110 S Membrane
NECFGCCN_06213 4.7e-140 S Membrane
NECFGCCN_06214 3.2e-44 S Domain of unknown function (DUF4312)
NECFGCCN_06215 5e-60 S Glycine-rich SFCGS
NECFGCCN_06216 2.6e-53 S PRD domain protein
NECFGCCN_06217 1.4e-60 cybC C Cytochrome b(562)
NECFGCCN_06218 8.4e-254 pmbA S Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD
NECFGCCN_06219 3.3e-95 yjgA S Belongs to the UPF0307 family
NECFGCCN_06220 1.7e-164 O protein import
NECFGCCN_06221 1.9e-217 mutY L A G-specific adenine glycosylase
NECFGCCN_06223 1.7e-37
NECFGCCN_06225 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NECFGCCN_06226 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NECFGCCN_06227 2.4e-90 cvpA S toxin biosynthetic process
NECFGCCN_06228 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NECFGCCN_06229 8.5e-40 L Integrase core domain
NECFGCCN_06230 3.6e-67 agcS E (Alanine) symporter
NECFGCCN_06231 2.1e-159 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NECFGCCN_06232 8.2e-199 gldA 1.1.1.6 C glycerol dehydrogenase
NECFGCCN_06233 1.3e-145 XK27_10475 S oxidoreductase
NECFGCCN_06234 5.1e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NECFGCCN_06235 9.1e-130 dcuR K Transcriptional Regulatory protein
NECFGCCN_06236 5e-293 dcuS 2.7.13.3 T signal transduction histidine kinase regulating citrate malate metabolism
NECFGCCN_06237 1.5e-13
NECFGCCN_06238 1.2e-101 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NECFGCCN_06239 1.2e-234 narU P nitrate nitrite transporter
NECFGCCN_06240 2.9e-88 ybjK K transcriptional regulator
NECFGCCN_06241 7.3e-214 smvA EGP Major facilitator superfamily
NECFGCCN_06242 2.2e-132 pcaR K transcriptional regulator
NECFGCCN_06243 1.7e-196 catB 5.5.1.1 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NECFGCCN_06244 1.2e-43 catC 5.3.3.4 Q Muconolactone delta-isomerase
NECFGCCN_06245 2.8e-168 catA 1.13.11.1 Q catechol 1,2-dioxygenase
NECFGCCN_06246 2e-258 benA 1.14.12.10 P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
NECFGCCN_06247 1.1e-91 benB 1.14.12.10 Q COG5517 Small subunit of phenylpropionate dioxygenase
NECFGCCN_06248 2.1e-188 pyrK 1.16.1.3, 1.3.1.14, 1.5.1.41, 3.5.2.3 C COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
NECFGCCN_06249 1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NECFGCCN_06250 2.8e-149 yddG EG of the drug metabolite transporter (DMT) superfamily
NECFGCCN_06251 8.5e-110 fdnG 1.17.1.9, 1.17.5.3 C Sulfate ABC transporter substrate-binding protein
NECFGCCN_06252 9.9e-258 narK P nitrate nitrite transporter
NECFGCCN_06253 0.0 narX 2.7.13.3 T Histidine kinase
NECFGCCN_06254 2.2e-111 narL K response regulator
NECFGCCN_06255 3.3e-269 ychO 3.2.1.14 GH18 M entry into host
NECFGCCN_06256 0.0 nasA 1.6.99.3, 1.7.7.2 C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism
NECFGCCN_06257 5e-159 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NECFGCCN_06258 3.8e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NECFGCCN_06261 1.4e-14 coiA 3.6.4.12 S Competence protein
NECFGCCN_06262 7.5e-16 T peptidase
NECFGCCN_06263 6e-158 rarD S Transporter
NECFGCCN_06264 2.6e-141 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NECFGCCN_06265 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NECFGCCN_06266 6.3e-133 yxkH G deacetylase
NECFGCCN_06267 3.9e-204 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NECFGCCN_06268 2.2e-123 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NECFGCCN_06269 6.2e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NECFGCCN_06270 7e-184 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NECFGCCN_06271 6.2e-67 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NECFGCCN_06272 2.2e-165 asp2 3.4.11.5 S Accessory Sec system protein Asp2
NECFGCCN_06273 9.4e-77 asp3 S Accessory Sec system protein Asp3
NECFGCCN_06274 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NECFGCCN_06275 5.7e-283 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NECFGCCN_06276 6.1e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NECFGCCN_06277 2.6e-17 S Accessory secretory protein Sec Asp4
NECFGCCN_06278 3.6e-16 S Accessory secretory protein Sec, Asp5
NECFGCCN_06279 4e-184 nss M transferase activity, transferring glycosyl groups
NECFGCCN_06280 1.2e-54 yabA L Involved in initiation control of chromosome replication
NECFGCCN_06281 2.5e-25 yaaT S stage 0 sporulation protein
NECFGCCN_06282 1.1e-62 pepF E oligoendopeptidase F
NECFGCCN_06283 4.2e-89 hpaC 1.5.1.36 C 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit
NECFGCCN_06284 0.0 hpaB 1.14.14.9 C 4-hydroxyphenylacetate 3-hydroxylase C terminal
NECFGCCN_06285 1.7e-170 hpaA K 4-hydroxyphenylacetate catabolism regulatory protein hpaA
NECFGCCN_06286 4.2e-253 EGP Major facilitator superfamily
NECFGCCN_06287 9.4e-144 hpaI 4.1.2.20, 4.1.2.52 G HpcH/HpaI aldolase/citrate lyase family
NECFGCCN_06288 1.2e-151 hpaH Q 2-oxohepta-3-ene-1,7-dioic acid hydratase
NECFGCCN_06289 1.3e-66 hpcD 4.1.1.68, 5.3.3.10 E 5-carboxymethyl-2-hydroxymuconate isomerase
NECFGCCN_06290 1.3e-167 hpaD 1.13.11.15 S 3,4-dihydroxyphenylacetate 2,3-dioxygenase
NECFGCCN_06291 4.5e-285 hpaE 1.2.1.60 C Belongs to the aldehyde dehydrogenase family
NECFGCCN_06292 8.4e-142 hpaG 4.1.1.68 Q 4-hydroxyphenylacetate degradation bifunctional isomerase
NECFGCCN_06293 2.8e-114 hpaG1 4.1.1.68 Q isomerase
NECFGCCN_06294 4.8e-73 hpaR K Homoprotocatechuate degradative operon repressor
NECFGCCN_06295 1e-19 ooxA C HI0933-like protein
NECFGCCN_06296 1.4e-20 ooxA C HI0933-like protein
NECFGCCN_06297 1.3e-185 allD 1.1.1.338, 1.5.1.21 C Belongs to the LDH2 MDH2 oxidoreductase family
NECFGCCN_06298 1e-229 dsd 4.3.1.18 E Putative serine dehydratase domain
NECFGCCN_06299 2.3e-278 dan 3.5.1.81, 3.5.1.82 Q N-acyl-D-aspartate D-glutamate deacylase
NECFGCCN_06300 1.4e-68 tdcF J translation initiation inhibitor, yjgF family
NECFGCCN_06301 1.5e-267 VVA1143 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECFGCCN_06302 5.6e-158 dgoK 2.7.1.58 G 2-keto-3-deoxy-galactonokinase
NECFGCCN_06303 9.7e-93 dgoA 4.1.2.14, 4.1.2.21, 4.1.3.42 G KDPG and KHG aldolase
NECFGCCN_06304 1.7e-146 hexR K transcriptional regulator
NECFGCCN_06305 7.5e-89 S Acetyltransferase
NECFGCCN_06306 7.7e-141 K N-acetyltransferase
NECFGCCN_06307 0.0 K transcriptional regulator
NECFGCCN_06308 1.5e-68 G PTS sugar transporter
NECFGCCN_06309 5.3e-78 2.7.1.191 G PTS system sorbose subfamily IIB component
NECFGCCN_06310 5.6e-117 G PTS system
NECFGCCN_06311 1.2e-152 G PTS mannose transporter subunit IID
NECFGCCN_06312 3.4e-181 M glucosamine--fructose-6-phosphate aminotransferase
NECFGCCN_06313 6.4e-190 agaS M Glucosamine--fructose-6-phosphate aminotransferase
NECFGCCN_06314 2.1e-147 S Transposase
NECFGCCN_06315 0.0 mdoB 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NECFGCCN_06316 1.1e-54 yjjA S Glycoprotein Receptor
NECFGCCN_06317 9.1e-133 dnaC L DNA replication protein
NECFGCCN_06318 2.1e-94 dnaT L it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'
NECFGCCN_06319 2.5e-80 yjjB S UPF0442 protein
NECFGCCN_06320 3.4e-138 yjjP S Membrane
NECFGCCN_06321 2e-227 pobA 1.14.13.2 CH Catalyzes the formation of protocatechuate from 4-hydroxybenzoate
NECFGCCN_06322 1.9e-161 pobR K transcriptional regulator
NECFGCCN_06323 1.5e-127 yjjQ K regulator
NECFGCCN_06324 3.4e-118 bglJ K transcriptional
NECFGCCN_06325 1.2e-79 ywhH S Prolyl-tRNA synthetase
NECFGCCN_06326 5.5e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NECFGCCN_06327 9e-139 fhuF S Iron reductase
NECFGCCN_06328 9e-187 hmsT 2.7.7.65 T Diguanylate cyclase
NECFGCCN_06329 1.8e-34 yjjZ S Protein of unknown function (DUF1435)
NECFGCCN_06330 2.8e-82 cstA T Carbon starvation protein
NECFGCCN_06331 2.2e-21 M Pilin isopeptide linkage domain protein
NECFGCCN_06332 1.7e-170 3.1.21.4 L Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
NECFGCCN_06333 4e-107
NECFGCCN_06334 1e-87 dpnA 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NECFGCCN_06335 2.9e-83 V ABC transporter
NECFGCCN_06336 1.1e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NECFGCCN_06337 1e-273 xynT G transporter
NECFGCCN_06338 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NECFGCCN_06339 1.5e-72 L endonuclease
NECFGCCN_06340 3.6e-53 L transposase
NECFGCCN_06341 1.7e-140 GM Polysaccharide pyruvyl transferase
NECFGCCN_06342 2.8e-278 tuaC 2.4.1.21 GT4,GT5 M glycosyl transferase family
NECFGCCN_06343 1.2e-39 peb1A ET Belongs to the bacterial solute-binding protein 3 family
NECFGCCN_06344 1.6e-48 1.1.1.1 C nadph quinone reductase
NECFGCCN_06345 4.4e-152 I Alpha/beta hydrolase family
NECFGCCN_06346 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NECFGCCN_06347 7.8e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NECFGCCN_06348 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NECFGCCN_06349 1.1e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NECFGCCN_06350 9.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NECFGCCN_06353 6.9e-91 ybhD K transcriptional regulator
NECFGCCN_06354 9.5e-83 csp K Cold-Shock Protein
NECFGCCN_06355 4.5e-127 rluA 5.4.99.28, 5.4.99.29 J Pseudouridine synthase
NECFGCCN_06356 1.8e-65 yaiL S protein conserved in bacteria
NECFGCCN_06357 4.1e-61 S Gamma-glutamyl cyclotransferase, AIG2-like
NECFGCCN_06358 1.1e-245 S type VI secretion protein
NECFGCCN_06359 5.2e-116 S Type VI secretion system protein ImpK
NECFGCCN_06360 0.0 oprF_2 M Belongs to the ompA family
NECFGCCN_06361 0.0 S Uncharacterized protein conserved in bacteria (DUF2345)
NECFGCCN_06362 1.9e-61 I phospholipase d transphosphatidylase
NECFGCCN_06363 2.8e-46 I phospholipase d transphosphatidylase
NECFGCCN_06364 4.8e-123 ydfF K transcriptional regulator
NECFGCCN_06365 8.1e-243 icd 1.1.1.42 C TIGRFAM isocitrate dehydrogenase, NADP-dependent
NECFGCCN_06366 8e-117 rluE 5.4.99.19, 5.4.99.20, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECFGCCN_06367 5.1e-86 nudJ L Belongs to the Nudix hydrolase family. NudJ subfamily
NECFGCCN_06368 2.2e-226 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NECFGCCN_06369 2.9e-111 hflD 4.3.2.2 S High frequency lysogenization protein hflD homolog
NECFGCCN_06370 1.7e-262 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NECFGCCN_06371 8.2e-63 G mannose-6-phosphate isomerase
NECFGCCN_06372 8.9e-150 K AraC family transcriptional regulator
NECFGCCN_06373 1.9e-121 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_06374 1.3e-271 T PhoQ Sensor
NECFGCCN_06375 5.1e-228 ycfD 1.14.11.47 S Cupin 4 family protein
NECFGCCN_06376 4.2e-82 pqqF O Belongs to the peptidase M16 family
NECFGCCN_06377 1.7e-39 pqqF O Belongs to the peptidase M16 family
NECFGCCN_06378 3.6e-221 pqqE S Pyrroloquinoline quinone biosynthesis protein E
NECFGCCN_06379 2e-45 pqqD S With PqqC converts a biosynthetic intermediate to pyrroloquinoline quinone
NECFGCCN_06380 1.2e-17 pqqC 1.3.3.11 H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
NECFGCCN_06381 5.3e-106 pqqC 1.3.3.11 H Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
NECFGCCN_06382 1.9e-180 pqqB 3.1.4.55 CO May be involved in the transport of PQQ or its precursor to the periplasm
NECFGCCN_06383 1.1e-186 3.4.13.19 E Zn-dependent dipeptidase, microsomal dipeptidase
NECFGCCN_06384 9.1e-189 S Alpha beta hydrolase
NECFGCCN_06385 3.1e-133 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_06386 6e-236 T PhoQ Sensor
NECFGCCN_06387 2e-33 secG U Preprotein translocase subunit SecG
NECFGCCN_06388 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NECFGCCN_06389 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NECFGCCN_06390 6.9e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NECFGCCN_06391 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NECFGCCN_06392 7.9e-157 rssA S Phospholipase, patatin family
NECFGCCN_06393 2.4e-102 estA E Lysophospholipase L1 and related esterases
NECFGCCN_06394 3.9e-90 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NECFGCCN_06395 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NECFGCCN_06396 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NECFGCCN_06397 3.4e-169 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NECFGCCN_06398 3.8e-93 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NECFGCCN_06399 4.8e-171 qor 1.6.5.5 C alcohol dehydrogenase
NECFGCCN_06400 0.0 tynA 1.4.3.21 Q amine oxidase
NECFGCCN_06401 0.0 paaN 1.2.1.91, 3.3.2.12 CI MaoC like domain
NECFGCCN_06402 1.1e-180 paaA 1.14.13.149 S Phenylacetic acid catabolic protein
NECFGCCN_06403 8.3e-50 paaB Q Phenylacetic acid degradation B
NECFGCCN_06404 1.4e-141 paaC 1.14.13.149 S Phenylacetic acid catabolic protein
NECFGCCN_06405 1.7e-95 paaD S Iron-sulfur cluster assembly protein
NECFGCCN_06406 4.7e-199 paaE C Oxidoreductase FAD-binding domain
NECFGCCN_06407 3.9e-131 paaF 4.2.1.17 I Enoyl-CoA hydratase/isomerase
NECFGCCN_06408 1.7e-07
NECFGCCN_06409 7.3e-81 K acetyltransferase
NECFGCCN_06410 4.5e-269 uxaB 1.1.1.11, 1.1.1.17, 1.1.1.57, 1.1.1.58 G Belongs to the mannitol dehydrogenase family. UxaB subfamily
NECFGCCN_06411 9.5e-84 ttr K histone acetyltransferase HPA2 and related acetyltransferases
NECFGCCN_06412 7.3e-256 yneF T Diguanylate cyclase
NECFGCCN_06413 1.2e-61 yneG S Domain of unknown function (DUF4186)
NECFGCCN_06414 3.4e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
NECFGCCN_06415 1.1e-259 sad 1.2.1.16, 1.2.1.20, 1.2.1.24, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
NECFGCCN_06416 2.6e-163 yneJ K Transcriptional regulator
NECFGCCN_06417 3.3e-83 ysnE K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECFGCCN_06418 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NECFGCCN_06419 4.9e-134 K transcriptional regulator
NECFGCCN_06420 4.2e-178 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NECFGCCN_06421 2.1e-211 ygbK 2.7.1.219, 2.7.1.220 G type III effector
NECFGCCN_06422 4.7e-197 dhaT C alcohol dehydrogenase
NECFGCCN_06423 1.8e-156 dapA_2 4.3.3.7 EM Belongs to the DapA family
NECFGCCN_06424 4.7e-247 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NECFGCCN_06425 6.7e-207 3.2.1.51 GH29 G BNR repeat-like domain
NECFGCCN_06426 5.9e-53 yjgK G Domain of unknown function (DUF386)
NECFGCCN_06427 2.8e-88 IQ NAD dependent epimerase/dehydratase family
NECFGCCN_06428 3e-72 yddE S phenazine biosynthesis protein PhzF
NECFGCCN_06429 2.8e-144 KLT Protein tyrosine kinase
NECFGCCN_06430 3.7e-98
NECFGCCN_06432 7.8e-171 L DNA integration
NECFGCCN_06434 8e-22 S PAAR motif
NECFGCCN_06435 2.8e-107
NECFGCCN_06436 1e-138 N type VI secretion protein
NECFGCCN_06437 0.0 N type VI secretion protein
NECFGCCN_06438 0.0 vasA S Type VI secretion
NECFGCCN_06439 2.3e-198 S type VI secretion protein
NECFGCCN_06440 1.4e-90 S Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113
NECFGCCN_06441 3.6e-76 S Type VI secretion system
NECFGCCN_06442 7.8e-218 M ImpA domain protein
NECFGCCN_06443 3e-162 G ABC-type sugar transport system periplasmic component
NECFGCCN_06445 2.2e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NECFGCCN_06446 2.1e-108 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NECFGCCN_06447 4.5e-45 ychH S cellular response to cadmium ion
NECFGCCN_06448 1.3e-68 S cog cog4699
NECFGCCN_06449 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECFGCCN_06450 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NECFGCCN_06451 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NECFGCCN_06452 1.6e-103 btuF P Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC
NECFGCCN_06453 3.4e-109 yadS S membrane
NECFGCCN_06454 1.1e-59 erpA C iron--sulfur cluster insertion protein erpA
NECFGCCN_06455 1.2e-256 clcA P Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response
NECFGCCN_06456 5.7e-244 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NECFGCCN_06458 6.8e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NECFGCCN_06459 1.8e-259 XK27_03190 S hydrolases of the HAD superfamily
NECFGCCN_06460 3.5e-07
NECFGCCN_06462 0.0 S cellulase activity
NECFGCCN_06463 1.9e-70
NECFGCCN_06464 3.8e-84 S Domain of unknown function (DUF1833)
NECFGCCN_06465 3.5e-90
NECFGCCN_06466 0.0 M tape measure protein
NECFGCCN_06467 8.3e-08 S YebO-like protein
NECFGCCN_06468 1.2e-46 S Protein of unknown function (DUF4035)
NECFGCCN_06469 3.7e-55 S tail assembly chaperone
NECFGCCN_06470 2.6e-83
NECFGCCN_06472 1.1e-53 S Structural component (Phage or Prophage Related)
NECFGCCN_06473 8.6e-70 S Bacteriophage HK97-gp10, putative tail-component
NECFGCCN_06474 3.6e-44 S head-tail adaptor
NECFGCCN_06475 2.3e-29 S Phage gp6-like head-tail connector protein
NECFGCCN_06476 2.1e-182 S TIGRFAM Phage major capsid protein, HK97
NECFGCCN_06477 8.2e-100 S Prohead protease
NECFGCCN_06478 7.8e-214 S TIGRFAM Phage portal protein, HK97
NECFGCCN_06480 1.1e-264 K terminase
NECFGCCN_06481 4.7e-69 L Phage terminase, small subunit
NECFGCCN_06482 2.9e-57 L HNH endonuclease
NECFGCCN_06483 1.8e-17
NECFGCCN_06484 5.8e-44 S Domain of unknown function (DUF4747)
NECFGCCN_06486 2.3e-105 GH19 S Chitinase class I
NECFGCCN_06487 5.3e-41 S Putative 3TM holin, Phage_holin_3
NECFGCCN_06488 3.6e-64 S Putative phage holin
NECFGCCN_06490 2.2e-81 S Protein of unknown function (DUF1133)
NECFGCCN_06491 4.2e-138 ydfU V Protein of unknown function (DUF968)
NECFGCCN_06492 3.2e-49 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
NECFGCCN_06493 1.8e-110 dam 2.1.1.37, 2.1.1.72 H Site-specific DNA-methyltransferase (Adenine-specific)
NECFGCCN_06494 2e-99 S DNA replication
NECFGCCN_06495 5.8e-25 S Domain of unknown function (DUF4222)
NECFGCCN_06496 4.7e-63
NECFGCCN_06497 5.7e-26 cro S DNA-binding transcriptional regulator Cro
NECFGCCN_06498 1.2e-112 c2 K Helix-turn-helix domain
NECFGCCN_06500 3.4e-114
NECFGCCN_06502 2.2e-57
NECFGCCN_06503 5.5e-31 S Membrane
NECFGCCN_06504 4.9e-12 S CsbD-like
NECFGCCN_06505 6.5e-117 dgdR K transcriptional regulator
NECFGCCN_06506 1.4e-22 dgdR K transcriptional regulator
NECFGCCN_06507 1.7e-271 ddc 2.6.1.76, 4.1.1.86 E decarboxylase
NECFGCCN_06508 1.9e-269 dat 2.6.1.76 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NECFGCCN_06509 6.8e-170 Z012_04120 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NECFGCCN_06510 5.5e-114 Z012_04125 P ABC-type nitrate sulfonate bicarbonate transport system permease component
NECFGCCN_06511 2.1e-126 ssuB_2 P ABC-type nitrate sulfonate bicarbonate transport system ATPase component
NECFGCCN_06512 1.1e-121 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NECFGCCN_06515 1e-73 cioB 1.10.3.14 C oxidase subunit
NECFGCCN_06516 9.8e-10
NECFGCCN_06518 8.6e-100 4.2.99.18 L oxidized base lesion DNA N-glycosylase activity
NECFGCCN_06519 2.8e-120 3.1.4.52 T EAL domain
NECFGCCN_06520 2.1e-290 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NECFGCCN_06521 3.2e-153 K transcriptional regulator
NECFGCCN_06522 0.0 ytrP 2.7.7.65 T Diguanylate cyclase
NECFGCCN_06523 6e-219 rpfG T metal-dependent phosphohydrolase, HD
NECFGCCN_06524 2.4e-184 ansB 3.5.1.1 EJ Belongs to the asparaginase 1 family
NECFGCCN_06525 1.3e-178 lpxL 2.3.1.241, 2.3.1.242, 2.3.1.243 M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)
NECFGCCN_06526 6.2e-106 leuE E Efflux Protein
NECFGCCN_06527 1.3e-38 ynaJ S Protein of unknown function (DUF2534)
NECFGCCN_06528 1.6e-08 yoaK
NECFGCCN_06529 4.3e-186 yeaP 2.7.7.65 T Diguanylate cyclase
NECFGCCN_06530 2.1e-38 yoaF
NECFGCCN_06531 1.2e-61 yeaO S MarR family transcriptional regulator
NECFGCCN_06532 1.8e-87 ybbK S Purine nucleoside phosphorylase
NECFGCCN_06533 8.2e-128 pyrG2 6.3.4.2 F CTP synthase
NECFGCCN_06534 8e-208 yeaN P Major facilitator superfamily
NECFGCCN_06535 5.3e-147 yeaM K Transcriptional regulator
NECFGCCN_06536 5.9e-71 yeaL S UPF0756 membrane protein
NECFGCCN_06537 1.6e-85 yeaK S YbaK prolyl-tRNA synthetase associated
NECFGCCN_06538 4.8e-210 waaU M Glycosyltransferase family 9 (heptosyltransferase)
NECFGCCN_06539 8.9e-37 msgA S Virulence protein msgA
NECFGCCN_06540 8.9e-61 umuD KT Belongs to the peptidase S24 family
NECFGCCN_06541 6.1e-214 umuC 2.7.7.7 L DNA polymerase
NECFGCCN_06542 1.7e-165 K transcriptional regulator
NECFGCCN_06543 7.8e-124 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
NECFGCCN_06544 1.9e-115 EGP Major Facilitator Superfamily
NECFGCCN_06545 4.1e-48 EGP Major Facilitator Superfamily
NECFGCCN_06546 8.2e-157 K transcriptional regulator
NECFGCCN_06547 4.4e-45 rpmE2 J 50S ribosomal protein L31
NECFGCCN_06548 2.3e-215 mntH P Mn2 and Fe2 transporters of the NRAMP family
NECFGCCN_06549 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NECFGCCN_06550 3.7e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NECFGCCN_06551 4.3e-07
NECFGCCN_06554 9e-07
NECFGCCN_06556 6.3e-70 badR K Transcriptional regulator, marr family
NECFGCCN_06557 1.2e-35 XK27_02060 S Transglycosylase associated protein
NECFGCCN_06558 6.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NECFGCCN_06559 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NECFGCCN_06560 5.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NECFGCCN_06561 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NECFGCCN_06562 2.3e-22 WQ51_00220 K Helix-turn-helix domain
NECFGCCN_06563 7.7e-81 S Protein of unknown function (DUF3278)
NECFGCCN_06564 0.0 smc D Required for chromosome condensation and partitioning
NECFGCCN_06565 2.9e-38 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NECFGCCN_06566 8.4e-142 P molecular chaperone
NECFGCCN_06567 7.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
NECFGCCN_06569 2.9e-47 Z012_11195 L Helix-turn-helix domain
NECFGCCN_06570 8.9e-38 Z012_11195 L Putative transposase DNA-binding domain
NECFGCCN_06571 4.1e-97 Z012_11195 L Putative transposase DNA-binding domain
NECFGCCN_06572 5.6e-180 umuC 2.7.7.7 L Binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)
NECFGCCN_06573 2e-42 umuC 2.7.7.7 L Binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)
NECFGCCN_06574 2e-76 L Peptidase S24-like
NECFGCCN_06575 7.8e-285 2.7.7.49 L Reverse transcriptase (RNA-dependent DNA polymerase)
NECFGCCN_06576 1e-21
NECFGCCN_06577 3.9e-41 S Antirestriction protein
NECFGCCN_06578 7.1e-37 2.7.7.7 L DNA polymerase
NECFGCCN_06579 9.8e-44
NECFGCCN_06580 3.3e-152 S Psort location Cytoplasmic, score 8.96
NECFGCCN_06582 3.8e-87 M invasion protein IagB
NECFGCCN_06583 2.1e-61 S TraM protein, DNA-binding
NECFGCCN_06584 1.9e-80
NECFGCCN_06585 3.8e-55 S TraA
NECFGCCN_06586 1.7e-56 traL S TraL protein
NECFGCCN_06587 2e-100 traE S TraE protein
NECFGCCN_06588 2.4e-133 traK 1.16.1.9 P TraK protein
NECFGCCN_06589 2.9e-236 tolA 2.7.13.3 NU transfer protein TraB
NECFGCCN_06590 7e-104 S Type IV conjugative transfer system lipoprotein (TraV)
NECFGCCN_06592 6.8e-36
NECFGCCN_06593 1e-11
NECFGCCN_06594 1.7e-72
NECFGCCN_06596 3.2e-60
NECFGCCN_06597 0.0 traG U F pilus assembly Type-IV secretion system for plasmid transfer
NECFGCCN_06598 2.2e-61 S Type-F conjugative transfer system protein (TrbI_Ftype)
NECFGCCN_06599 1.7e-116 traW S Type-F conjugative transfer system protein TraW
NECFGCCN_06600 5.7e-65
NECFGCCN_06601 2.3e-200 traU S PFAM TraU
NECFGCCN_06603 3.9e-116 trbC S Type-F conjugative transfer system pilin assembly protein
NECFGCCN_06604 0.0 traN S F plasmid TraN appears to recognize OmpA in the recipient cell
NECFGCCN_06605 3.2e-37 S Conjugal transfer protein TrbE
NECFGCCN_06606 8.2e-36
NECFGCCN_06607 3e-56
NECFGCCN_06608 2.3e-139 traF CO Type IV secretion system pilus assembly protein
NECFGCCN_06609 1.4e-37 S Type-F conjugative transfer system pilin chaperone (TraQ)
NECFGCCN_06610 6.9e-101 CO F plasmid transfer operon protein
NECFGCCN_06611 1.2e-76
NECFGCCN_06612 8.8e-251 traH S PFAM Conjugative relaxosome accessory transposon protein
NECFGCCN_06613 0.0 S TraG-like protein, N-terminal region
NECFGCCN_06614 2.3e-62 S TraG-like protein, N-terminal region
NECFGCCN_06616 1.1e-114 ylpA S TraT complement resistance
NECFGCCN_06617 0.0 traD U Type IV secretion system coupling protein
NECFGCCN_06618 0.0 traI L ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NECFGCCN_06619 2.5e-135 S TraX protein
NECFGCCN_06620 4.2e-96 finO T Fertility inhibition protein N terminal
NECFGCCN_06621 7.2e-56
NECFGCCN_06622 3.1e-12 CP_0355 S CAAX protease self-immunity
NECFGCCN_06623 6.8e-173 S Microcin H47 secretion protein
NECFGCCN_06625 1.1e-11 S ABC-2 family transporter protein
NECFGCCN_06627 1.4e-07 L Psort location Cytoplasmic, score 8.96
NECFGCCN_06629 3.7e-26 soj D ATPases involved in chromosome partitioning
NECFGCCN_06631 8.4e-11 bipA S protein secretion
NECFGCCN_06632 3e-31 bipA S protein secretion
NECFGCCN_06633 3.7e-148 lcnDR2 V Domain of unknown function (DUF4135)
NECFGCCN_06634 1.2e-44 yfaE C Ferredoxin
NECFGCCN_06635 1.5e-216 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECFGCCN_06636 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NECFGCCN_06637 1.2e-137 ubiG 2.1.1.222, 2.1.1.64 H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway
NECFGCCN_06638 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NECFGCCN_06639 0.0 rcsC 2.7.13.3 T PhoQ Sensor
NECFGCCN_06640 4.1e-113 rcsB K Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions
NECFGCCN_06641 0.0 rcsD 2.7.13.3, 4.6.1.1 T Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB
NECFGCCN_06642 1.6e-194 ompC M Belongs to the Gram-negative porin family
NECFGCCN_06643 5.3e-195 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NECFGCCN_06644 1.8e-190 ada 2.1.1.63, 3.2.2.21 FL Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NECFGCCN_06645 9.1e-121 alkB 1.14.11.33 L Alkylated DNA repair protein
NECFGCCN_06646 3.7e-304 yojI PQ Cyclic peptide transporter
NECFGCCN_06647 1.2e-263 mgtE P Acts as a magnesium transporter
NECFGCCN_06648 5.1e-189 P COG0659 Sulfate permease and related transporters (MFS superfamily)
NECFGCCN_06649 0.0 mqo 1.1.5.4 C malate quinone oxidoreductase
NECFGCCN_06650 3.9e-84 eco M General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases
NECFGCCN_06651 1.8e-193 ydiK_1 S permease
NECFGCCN_06653 0.0 yejM S Hydrolase of alkaline phosphatase superfamily
NECFGCCN_06654 9.3e-32 yejL S Belongs to the UPF0352 family
NECFGCCN_06655 3.8e-182 ndpA S Nucleoid-associated protein
NECFGCCN_06656 4.6e-124 glcR 3.6.4.12 K transcriptional regulator
NECFGCCN_06657 1.1e-107 nudK 3.6.1.13 L Nudix-type nucleoside diphosphatase, YffH AdpP family
NECFGCCN_06658 5e-248 nylB V Beta-lactamase
NECFGCCN_06659 1.7e-154 K Transcriptional regulator
NECFGCCN_06660 6.7e-44 rplY J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NECFGCCN_06661 0.0 yejH L Type III restriction protein res subunit
NECFGCCN_06662 5.1e-133 rsuA 5.4.99.19, 5.4.99.20, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NECFGCCN_06663 1e-210 bcr EGP Major facilitator Superfamily
NECFGCCN_06664 4.3e-61 yejG S YejG-like protein
NECFGCCN_06665 4.9e-285 yejF P ATPase activity
NECFGCCN_06666 1.8e-176 yejE P ABC transporter (Permease
NECFGCCN_06667 1.3e-199 yejB P ABC transporter (permease)
NECFGCCN_06668 0.0 yejA E ABC-type oligopeptide transport system, periplasmic component
NECFGCCN_06669 3.7e-285 rtn T Involved in resistance to the phages N4 and lambda
NECFGCCN_06670 5.6e-98 spr 3.4.17.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NECFGCCN_06671 9e-122 lpxT 2.7.4.29 I Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P)
NECFGCCN_06672 1.4e-173 yeiR S cobalamin synthesis protein, P47K
NECFGCCN_06673 1.1e-278 mtlK 1.1.1.11, 1.1.1.17, 1.1.1.289, 1.1.1.57, 1.1.1.58, 1.1.1.67, 2.7.1.17 G Belongs to the mannitol dehydrogenase family
NECFGCCN_06674 2.1e-232 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NECFGCCN_06675 4.4e-103 efp J Elongation factor P
NECFGCCN_06676 1.4e-139 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NECFGCCN_06677 1e-210 setB EGP Major facilitator Superfamily
NECFGCCN_06678 2.2e-186 fruB 2.7.1.121, 2.7.1.202, 2.7.3.9 G Bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
NECFGCCN_06679 1.1e-175 fruK 2.7.1.11, 2.7.1.56 H belongs to the carbohydrate kinase PfkB family
NECFGCCN_06680 1.6e-270 fruA 2.7.1.202 G PTS system, fructose subfamily, IIC subunit
NECFGCCN_06681 2e-160 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NECFGCCN_06682 5e-185 yeiH S Belongs to the UPF0324 family
NECFGCCN_06683 3.6e-157 yeiE K transcriptional regulator
NECFGCCN_06684 2.7e-277 lysP E amino acid
NECFGCCN_06685 8.5e-31
NECFGCCN_06686 9.4e-21
NECFGCCN_06688 2.8e-157 XK27_09825 V abc transporter atp-binding protein
NECFGCCN_06692 8.4e-67 anK3 G response to abiotic stimulus
NECFGCCN_06693 1e-45 malI K Transcriptional regulator
NECFGCCN_06694 3.3e-297 malX 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G PTS system
NECFGCCN_06695 1e-223 malY 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NECFGCCN_06696 2.5e-189 corA P transporter
NECFGCCN_06697 4.2e-32 ydfZ_1 S selenium-binding protein YdfZ
NECFGCCN_06698 1e-89
NECFGCCN_06699 5.6e-48 MA20_23345 S membrane
NECFGCCN_06700 3.5e-227 yedE S transporter component
NECFGCCN_06701 1.2e-38 yedF O Belongs to the sulfur carrier protein TusA family
NECFGCCN_06702 2.1e-59 ycgX S Phage envelope protein
NECFGCCN_06703 1.1e-22 yqaE S homolog of Blt101
NECFGCCN_06704 7.5e-183 gap 1.2.1.12, 1.2.1.72 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NECFGCCN_06705 1.1e-270 aldA 1.2.1.21, 1.2.1.22 C belongs to the aldehyde dehydrogenase family
NECFGCCN_06706 2.7e-143 ydcF S DUF218 domain
NECFGCCN_06707 4.9e-238 proP EGP Major facilitator superfamily
NECFGCCN_06708 5.8e-261 cycA E amino acid
NECFGCCN_06709 1.5e-183 astE 3.5.1.96 E Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily
NECFGCCN_06710 1.3e-254 astB 3.5.3.23 E Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)
NECFGCCN_06711 4.1e-270 astD 1.2.1.71 C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate
NECFGCCN_06712 2.7e-188 astA 2.3.1.109 E arginine N-succinyltransferase
NECFGCCN_06713 5.8e-230 argD 2.6.1.11, 2.6.1.17, 2.6.1.81 E aminotransferase
NECFGCCN_06714 6.1e-246 gdhA 1.4.1.3, 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NECFGCCN_06715 1.1e-176 C Aldo keto reductase
NECFGCCN_06716 3.6e-158 K Transcriptional regulator
NECFGCCN_06717 1.7e-62 marR1 K transcriptional regulator
NECFGCCN_06718 9.8e-88 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NECFGCCN_06719 0.0 kefC P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NECFGCCN_06720 2e-102 kefF C Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC
NECFGCCN_06721 4.4e-33 ygdi3 S (LipO)protein
NECFGCCN_06722 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthetase ammonia chain
NECFGCCN_06723 2.2e-218 carA 6.3.5.5 F Belongs to the CarA family
NECFGCCN_06724 7.9e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NECFGCCN_06725 2.6e-158 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NECFGCCN_06726 9.4e-286 citF 2.8.3.10 H Citrate lyase alpha subunit
NECFGCCN_06727 9.9e-155 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NECFGCCN_06728 3.8e-42 citD 4.1.3.34 C Covalent carrier of the coenzyme of citrate lyase
NECFGCCN_06729 4.1e-192 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NECFGCCN_06730 4.8e-217 citS P Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system)
NECFGCCN_06731 1.6e-28 oadG 4.1.1.3 C oxaloacetate decarboxylase gamma chain
NECFGCCN_06732 8.4e-294 oadA 2.3.1.12, 4.1.1.3, 6.4.1.1 CI Oxaloacetate
NECFGCCN_06733 1.8e-224 oadB 4.1.1.3 C Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NECFGCCN_06734 1.1e-242 citA 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NECFGCCN_06735 1.7e-117 citB K transcriptional regulatory protein
NECFGCCN_06736 4.8e-111 alaS_2 6.1.1.7 S Alanyl-tRNA synthetase
NECFGCCN_06737 2.9e-168 K transcriptional regulator
NECFGCCN_06738 1.4e-57 yhaI S Protein of unknown function (DUF805)
NECFGCCN_06739 1.5e-169 rihC 3.2.2.1 F Belongs to the IUNH family
NECFGCCN_06740 1e-173 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NECFGCCN_06741 1.9e-77 fkpB 5.2.1.8 G Peptidyl-prolyl cis-trans
NECFGCCN_06742 3.7e-90 lspA 3.4.23.36 M This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NECFGCCN_06743 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NECFGCCN_06744 3e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NECFGCCN_06745 9.1e-30
NECFGCCN_06746 9.5e-169 nhaR K transcriptional regulator
NECFGCCN_06747 8.6e-205 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NECFGCCN_06748 9.8e-179 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NECFGCCN_06749 0.0 dnaK O Heat shock 70 kDa protein
NECFGCCN_06750 1.1e-63 yaaI S Belongs to the UPF0412 family
NECFGCCN_06751 1.9e-130 yaaW S protein conserved in bacteria
NECFGCCN_06752 4.2e-98 yaaH S GPR1 FUN34 yaaH family protein
NECFGCCN_06753 4.2e-226 tphA EGP Major facilitator superfamily
NECFGCCN_06754 3.1e-104 mog 2.7.7.75, 2.8.1.12 H Molybdenum cofactor
NECFGCCN_06755 6.1e-174 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NECFGCCN_06756 1.5e-256 yaaJ E alanine symporter
NECFGCCN_06757 7.2e-141 yaaA S Belongs to the UPF0246 family
NECFGCCN_06758 3.8e-10
NECFGCCN_06759 1.4e-245 thrC 4.2.3.1 E Threonine synthase
NECFGCCN_06760 7.5e-177 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NECFGCCN_06761 0.0 thrA 1.1.1.3, 2.7.2.4 E belongs to the aspartokinase family
NECFGCCN_06762 2.1e-115 trmJ 2.1.1.200 J Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NECFGCCN_06763 5.1e-133 K Two component transcriptional regulator, winged helix family
NECFGCCN_06764 4.2e-245 creD V Inner membrane protein involved in colicin E2 resistance
NECFGCCN_06765 4.4e-261 T PhoQ Sensor
NECFGCCN_06766 2.5e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NECFGCCN_06767 4.2e-83 creA S protein conserved in bacteria
NECFGCCN_06768 4.3e-166 rob K Binds to the right arm of the replication origin oriC
NECFGCCN_06769 1.4e-118 gpmB 5.4.2.12 G Belongs to the phosphoglycerate mutase family
NECFGCCN_06770 3.4e-86 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
NECFGCCN_06771 3e-51 trpR K This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
NECFGCCN_06772 0.0 slt GH23 M Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NECFGCCN_06773 0.0 yjjK 3.6.3.25 S abc transporter atp-binding protein
NECFGCCN_06774 5.2e-242 nadR 2.7.1.22, 2.7.7.1 H transcriptional regulator
NECFGCCN_06775 2e-258 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NECFGCCN_06776 6.9e-181 serB 3.1.3.3 E phosphoserine phosphatase
NECFGCCN_06777 1e-111 smp 2.4.1.15, 2.4.1.347, 2.7.13.3, 6.3.1.20 GT20 S membrane protein affecting hemolysin expression
NECFGCCN_06778 9.6e-194 lplA 6.3.1.20 H Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes
NECFGCCN_06779 1.5e-132 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NECFGCCN_06780 1.1e-114 yqgA S Membrane
NECFGCCN_06781 0.0 speC 4.1.1.17, 4.1.1.18, 4.1.1.19 E decarboxylase
NECFGCCN_06782 3.5e-230 nupG G Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force
NECFGCCN_06783 2.4e-203 mltC GH23 M Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
NECFGCCN_06784 6.3e-47 yggX C Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NECFGCCN_06785 1.8e-206 mutY L a g-specific adenine glycosylase
NECFGCCN_06786 1.8e-138 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NECFGCCN_06787 1e-56 yggL S protein conserved in bacteria
NECFGCCN_06788 5.7e-124 yggN S Protein of unknown function (DUF2884)
NECFGCCN_06789 3.2e-207 P Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_06790 6.2e-143 3.6.3.17 P Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NECFGCCN_06791 1.2e-191 G PFAM Periplasmic binding protein LacI transcriptional regulator
NECFGCCN_06792 7.4e-219 hemN H Involved in the biosynthesis of porphyrin-containing compound
NECFGCCN_06793 4.1e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NECFGCCN_06794 2.1e-45 yggU S Belongs to the UPF0235 family
NECFGCCN_06795 9.1e-93 yggT S integral membrane protein
NECFGCCN_06796 1.1e-124 yggS E Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NECFGCCN_06797 2.2e-171 yggR NU twitching motility protein
NECFGCCN_06798 5.7e-115 corR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NECFGCCN_06799 1e-72 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NECFGCCN_06800 7.4e-103 yqgE K Belongs to the UPF0301 (AlgH) family
NECFGCCN_06801 1.8e-181 gshB 6.3.2.2, 6.3.2.3 H Belongs to the prokaryotic GSH synthase family
NECFGCCN_06802 2.6e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NECFGCCN_06803 4.1e-127 endA 3.1.21.1 L endonuclease I
NECFGCCN_06804 6.5e-81 sprT S Belongs to the SprT family
NECFGCCN_06805 1.9e-256 galP EGP Major facilitator Superfamily
NECFGCCN_06806 7.6e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NECFGCCN_06807 0.0 speA 4.1.1.19 H Catalyzes the biosynthesis of agmatine from arginine
NECFGCCN_06808 2e-177 speB 3.5.3.11 E Belongs to the arginase family
NECFGCCN_06809 5.7e-193 EGP Major facilitator Superfamily
NECFGCCN_06810 7.6e-60 ndoA 1.7.1.15 C Rieske [2Fe-2S] domain
NECFGCCN_06811 1.2e-54
NECFGCCN_06812 1.7e-206 carAa P Rieske [2Fe-2S] domain
NECFGCCN_06813 4.5e-132 IQ KR domain
NECFGCCN_06814 2.3e-142 K helix_turn_helix isocitrate lyase regulation
NECFGCCN_06815 2.1e-179 todE C Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NECFGCCN_06816 3.1e-223 andAa 1.18.1.3, 1.7.1.15 P Pyridine nucleotide-disulphide oxidoreductase
NECFGCCN_06817 2.5e-228 sauU G Major Facilitator Superfamily
NECFGCCN_06818 5.5e-100 G WxcM-like, C-terminal
NECFGCCN_06819 7.4e-138 I Alpha/beta hydrolase family
NECFGCCN_06820 1.4e-139 IQ KR domain
NECFGCCN_06821 3.1e-128 nadX 1.4.1.21 H Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate
NECFGCCN_06822 1.8e-281 aldA 1.2.1.3, 1.2.1.8 C Aldehyde dehydrogenase family
NECFGCCN_06823 5.7e-305 2.2.1.6, 4.1.1.75 C Thiamine pyrophosphate enzyme, central domain
NECFGCCN_06824 8.5e-243 oprD S outer membrane porin, OprD family
NECFGCCN_06825 3.9e-131 yggG O metalloprotease
NECFGCCN_06826 0.0 mdtB V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_06827 1.1e-34 mdtC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_06829 0.0 sbcC L ATPase involved in DNA repair
NECFGCCN_06830 1.4e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NECFGCCN_06831 0.0 GM domain, Protein
NECFGCCN_06832 4.7e-207 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NECFGCCN_06833 6.9e-73 S Protein of unknown function (DUF1697)
NECFGCCN_06834 1.3e-171 glpB 1.1.5.3 C Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NECFGCCN_06835 7.2e-225 glpC 1.1.5.3 C dehydrogenase subunit C
NECFGCCN_06836 8e-143 rhmA 4.1.2.20, 4.1.2.52, 4.1.2.53 G Belongs to the HpcH HpaI aldolase family
NECFGCCN_06837 6.9e-229 rhmT G Major facilitator superfamily
NECFGCCN_06838 1.7e-237 rhmD 4.2.1.90 M Catalyzes the dehydration of L-rhamnonate to 2-keto-3- deoxy-L-rhamnonate (KDR)
NECFGCCN_06839 3.5e-143 rhmR K Transcriptional regulator
NECFGCCN_06840 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NECFGCCN_06841 4.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NECFGCCN_06842 4.7e-168 fhuR K transcriptional regulator (lysR family)
NECFGCCN_06844 1.6e-44
NECFGCCN_06845 5.8e-69 K Helix-turn-helix
NECFGCCN_06849 1.3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NECFGCCN_06850 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NECFGCCN_06851 9.2e-09 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NECFGCCN_06852 4.5e-250 cycA E permease
NECFGCCN_06853 1.7e-38 ynzC S UPF0291 protein
NECFGCCN_06854 2.8e-288 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NECFGCCN_06855 0.0 acrD V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NECFGCCN_06856 1.7e-60 yffB 1.20.4.1 P Belongs to the ArsC family
NECFGCCN_06857 1.3e-218 dapE 3.5.1.18 E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NECFGCCN_06858 2.5e-32 ypfN S Uncharacterised protein family (UPF0370)
NECFGCCN_06859 8.2e-128 ypfH S Phospholipase Carboxylesterase
NECFGCCN_06860 0.0 tmcA 2.3.1.193, 2.3.1.57 J Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)
NECFGCCN_06861 3.3e-150 ypfJ S zinc metallopeptidase
NECFGCCN_06862 1.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NECFGCCN_06863 4e-187 bamC M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NECFGCCN_06864 1.2e-163 dapA 2.5.1.72, 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NECFGCCN_06865 3.7e-102 gcvR E glycine cleavage system
NECFGCCN_06866 1.1e-88 bcp 1.11.1.15 O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NECFGCCN_06867 1.3e-172 perM S permease
NECFGCCN_06868 7e-270 bepA S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state
NECFGCCN_06869 6.3e-55 arsC 1.20.4.1 P arsenate reductase
NECFGCCN_06870 1.1e-148 S Transposase
NECFGCCN_06871 4.7e-128 hda L Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA
NECFGCCN_06872 6e-225 uraA F Xanthine uracil
NECFGCCN_06873 5.3e-110 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NECFGCCN_06874 3.1e-291 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_06875 7.5e-166 bglK 2.7.1.85 GK ROK family
NECFGCCN_06876 1.7e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NECFGCCN_06877 6e-117 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NECFGCCN_06878 0.0 ppk 2.7.4.1 H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NECFGCCN_06879 3.7e-290 ppx 3.6.1.11, 3.6.1.40 FP Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities
NECFGCCN_06880 0.0 yfgF T cyclic-guanylate-specific phosphodiesterase activity
NECFGCCN_06881 6.8e-23 yfgG S Protein of unknown function (DUF2633)
NECFGCCN_06882 4.9e-29 cysL_1 K transcriptional regulator
NECFGCCN_06883 2.8e-45 glnQ E abc transporter atp-binding protein
NECFGCCN_06884 3.6e-181 D nuclear chromosome segregation
NECFGCCN_06885 1.3e-81 V VanZ like family
NECFGCCN_06886 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NECFGCCN_06887 6e-170 yhjX P Major Facilitator
NECFGCCN_06888 2.9e-103 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NECFGCCN_06889 5.6e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NECFGCCN_06890 1.4e-234 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NECFGCCN_06891 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NECFGCCN_06892 1.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NECFGCCN_06893 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NECFGCCN_06894 3.1e-83 nrdI F Belongs to the NrdI family
NECFGCCN_06895 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NECFGCCN_06896 6.5e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NECFGCCN_06897 4.3e-176 prmA J Ribosomal protein L11 methyltransferase
NECFGCCN_06898 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
NECFGCCN_06899 2.4e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NECFGCCN_06900 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NECFGCCN_06901 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NECFGCCN_06902 7.9e-135 ykuT M mechanosensitive ion channel
NECFGCCN_06903 3.3e-86 sigH K DNA-templated transcription, initiation
NECFGCCN_06904 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NECFGCCN_06905 9.9e-255 S phospholipase Carboxylesterase
NECFGCCN_06906 8.5e-176 mocA 1.1.1.91 C oxidoreductases (related to aryl-alcohol dehydrogenases)
NECFGCCN_06907 5.7e-146 hisJ_2 ET Belongs to the bacterial solute-binding protein 3 family
NECFGCCN_06908 1.7e-221 hipO 3.5.1.32 S amidohydrolase
NECFGCCN_06909 3.8e-65 S integral membrane protein
NECFGCCN_06910 4.8e-16 K regulation of DNA-templated transcription, elongation
NECFGCCN_06911 8.9e-209 P periplasmic binding protein
NECFGCCN_06912 8.5e-172 irp6B P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NECFGCCN_06913 9.7e-141 fhuC_1 3.6.3.34 HP (ABC) transporter
NECFGCCN_06914 6.1e-205 yiaV V secretion protein HlyD family
NECFGCCN_06915 7.8e-55 yiaW S Protein of unknown function (DUF3302)
NECFGCCN_06916 5.5e-141 K Winged helix-turn-helix DNA binding
NECFGCCN_06917 1.5e-169 scrK 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
NECFGCCN_06918 2.2e-258 scrY M Maltoporin (phage lambda and maltose receptor)
NECFGCCN_06919 2.1e-68 MA20_06395 K transcriptional regulator
NECFGCCN_06920 4e-148 ghr 1.1.1.31, 1.1.1.60, 1.1.1.79 I Dehydrogenase
NECFGCCN_06921 3.4e-203 cdaR KT Putative sugar diacid recognition
NECFGCCN_06922 1e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NECFGCCN_06923 2.9e-254 G Sugar (and other) transporter
NECFGCCN_06924 5.4e-169 3.1.1.15 G gluconolactonase
NECFGCCN_06925 1.6e-241 G Major Facilitator
NECFGCCN_06926 9.6e-37 lacI K binds specific sites in lac operon resulting in DNA looping between the operators
NECFGCCN_06927 0.0 lacZ 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NECFGCCN_06928 1.7e-216 P Major facilitator superfamily
NECFGCCN_06929 3.5e-210 S AAA ATPase domain
NECFGCCN_06930 9.2e-40
NECFGCCN_06931 3.3e-29 penP 3.5.2.6 V Beta-lactamase
NECFGCCN_06932 9.7e-18
NECFGCCN_06933 4.9e-103 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NECFGCCN_06938 1e-148 dmsC S Dimethyl sulfoxide reductase
NECFGCCN_06939 8e-213 ycaD EGP Major facilitator superfamily
NECFGCCN_06940 4.9e-147 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NECFGCCN_06941 0.0 pflB 2.3.1.54 C formate C-acetyltransferase glycine radical
NECFGCCN_06942 2.3e-156 focA P Formate nitrite
NECFGCCN_06943 0.0 ycaO O redox protein regulator of disulfide bond formation
NECFGCCN_06944 3.9e-122 ycaP S Membrane
NECFGCCN_06945 5e-10
NECFGCCN_06946 4.3e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NECFGCCN_06947 5.6e-239 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NECFGCCN_06948 2.2e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NECFGCCN_06949 0.0 rpsA 1.17.7.4 J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
NECFGCCN_06950 4.3e-46 himD K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
NECFGCCN_06951 0.0 ycaI S DNA internalization-related competence protein ComEC Rec2
NECFGCCN_06952 7.5e-303 msbA V Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
NECFGCCN_06953 1.3e-179 lpxK 2.7.1.130 F Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
NECFGCCN_06954 2.7e-235 ycaQ S protein conserved in bacteria
NECFGCCN_06955 6.9e-26 ycaR 2.7.1.130 S Belongs to the UPF0434 family
NECFGCCN_06956 6.3e-134 kdsB 2.7.7.38 M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NECFGCCN_06957 7.2e-169 ycbJ S Phosphotransferase enzyme family
NECFGCCN_06958 7.8e-143 ycbC S Gram-negative-bacterium-type cell wall biogenesis
NECFGCCN_06959 7.4e-149 cmoM GT2,GT4 J Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs
NECFGCCN_06960 1e-248 mukF D Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
NECFGCCN_06961 2.3e-125 mukE D Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NECFGCCN_06962 0.0 mukB 3.5.4.40 D Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NECFGCCN_06963 0.0 ycbB M protein conserved in bacteria
NECFGCCN_06965 1.3e-100 ycbK S protein conserved in bacteria
NECFGCCN_06966 6.1e-125 ycbL 3.1.2.6 P COG0491 Zn-dependent hydrolases, including glyoxylases
NECFGCCN_06967 8.6e-226 aspC 2.6.1.1, 2.6.1.57 E aminotransferase
NECFGCCN_06968 1.8e-206 ompF M Belongs to the Gram-negative porin family
NECFGCCN_06969 3.5e-271 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NECFGCCN_06970 8.3e-76 K Transcriptional
NECFGCCN_06971 8.4e-221 dpaL 4.3.1.15, 4.3.1.19 E Diaminopropionate ammonia-lyase
NECFGCCN_06972 3.5e-225 sdaC E Serine transporter
NECFGCCN_06973 1.5e-209 3.5.1.6, 3.5.1.87, 3.5.3.9 E the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia
NECFGCCN_06974 9e-212 3.5.1.32 S amidohydrolase
NECFGCCN_06975 4.6e-230 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NECFGCCN_06976 0.0 pepN 3.4.11.2 E aminopeptidase N
NECFGCCN_06977 1.8e-38 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
NECFGCCN_06978 1.1e-158 holB 2.7.7.7 L dna polymerase iii
NECFGCCN_06979 3.5e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NECFGCCN_06981 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NECFGCCN_06982 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NECFGCCN_06983 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NECFGCCN_06984 6e-217 ftsW D Belongs to the SEDS family
NECFGCCN_06985 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NECFGCCN_06986 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NECFGCCN_06987 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NECFGCCN_06988 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NECFGCCN_06989 3.9e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NECFGCCN_06990 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NECFGCCN_06991 1.8e-122 atpB C it plays a direct role in the translocation of protons across the membrane
NECFGCCN_06992 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NECFGCCN_06993 8.9e-183 femA 2.3.2.10, 2.3.2.16 V FemAB family
NECFGCCN_06994 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NECFGCCN_06995 8.9e-159
NECFGCCN_06996 0.0 S Protein of unknown function (DUF1176)
NECFGCCN_06997 8e-100 yjdC K Transcriptional regulator
NECFGCCN_06998 0.0 dsbD 1.8.1.8 CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps
NECFGCCN_06999 2e-52 cutA 4.2.3.1 P Involved in resistance toward heavy metals
NECFGCCN_07000 5.5e-226 dcuA S Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NECFGCCN_07001 9.5e-272 aspA 4.3.1.1 E Aspartate ammonia-lyase
NECFGCCN_07002 5.9e-61 fxsA S protein affecting phage T7 exclusion by the F plasmid
NECFGCCN_07003 4.8e-219 yjeH E amino acid
NECFGCCN_07004 9.1e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NECFGCCN_07005 9.9e-212 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NECFGCCN_07007 1.6e-87 alkD L Dna alkylation repair
NECFGCCN_07008 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NECFGCCN_07013 8.2e-200 S the current gene model (or a revised gene model) may contain a frame shift
NECFGCCN_07014 7.3e-231 2.7.13.3 T protein histidine kinase activity
NECFGCCN_07015 4.5e-201 hpk9 2.7.13.3 T protein histidine kinase activity
NECFGCCN_07016 1.6e-17 hycB C Formate hydrogenlyase
NECFGCCN_07017 0.0 hycC CP formate hydrogenlyase subunit 3
NECFGCCN_07018 1.4e-159 hycD C HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide
NECFGCCN_07019 0.0 hycE C HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide
NECFGCCN_07020 3.4e-89 hycF C the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3
NECFGCCN_07021 5.1e-147 hycG C NADH ubiquinone oxidoreductase, 20
NECFGCCN_07022 9.3e-71 hycH E Formate hydrogen-lyase
NECFGCCN_07023 2.1e-82 hycI 3.4.23.51 C hydrogenase 3 maturation protease
NECFGCCN_07024 5.4e-47 S Toxin SymE, type I toxin-antitoxin system
NECFGCCN_07025 1.1e-288 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NECFGCCN_07026 1.8e-254 ascF 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Phosphotransferase System
NECFGCCN_07027 1.2e-183 ascG K Transcriptional regulator
NECFGCCN_07028 1.3e-101 hydN C electron transport
NECFGCCN_07029 0.0 hypF O Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NECFGCCN_07030 7.9e-172 hoxN S rRNA processing
NECFGCCN_07031 1.3e-202 norW 1.7.1.15 C One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase
NECFGCCN_07032 1.3e-49 norV 1.6.3.4 C uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
NECFGCCN_07033 6e-155 XK27_03015 S permease
NECFGCCN_07035 0.0 yhgF K Transcriptional accessory protein
NECFGCCN_07036 2.2e-145 moaF S MoaF C-terminal domain
NECFGCCN_07037 2.4e-136 1.1.1.100, 1.1.1.304, 1.1.1.76 S KR domain
NECFGCCN_07038 0.0 atsA 3.1.6.1 P COG3119 Arylsulfatase A and related enzymes
NECFGCCN_07039 1.1e-214 atsB C Radical SAM domain protein
NECFGCCN_07040 5.6e-121 moaR K transcriptional regulator
NECFGCCN_07041 2.3e-131 EGP Major facilitator Superfamily
NECFGCCN_07042 7.5e-178 ddpB P Binding-protein-dependent transport systems inner membrane component
NECFGCCN_07043 7.7e-299 ddpA E Extracellular solute-binding protein, family 5
NECFGCCN_07044 5.1e-130 rimL J Acetyltransferases including N-acetylases of ribosomal proteins
NECFGCCN_07045 0.0 betA 1.1.99.1 E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NECFGCCN_07046 1e-276 betB 1.2.1.8 C belongs to the aldehyde dehydrogenase family
NECFGCCN_07047 3.1e-104 betI K Repressor involved in choline regulation of the bet genes
NECFGCCN_07048 0.0 betT M Belongs to the BCCT transporter (TC 2.A.15) family
NECFGCCN_07049 8e-76 ivy S Inhibitor of vertebrate lysozyme
NECFGCCN_07050 3.5e-230 ybdG M Mechanosensitive Ion channel
NECFGCCN_07051 7.2e-161 K LysR substrate binding domain
NECFGCCN_07052 4.7e-103 gstN 2.5.1.18 O Glutathione S-transferase
NECFGCCN_07053 3.3e-141 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
NECFGCCN_07054 1e-150 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NECFGCCN_07055 1.1e-187 G Belongs to the binding-protein-dependent transport system permease family
NECFGCCN_07056 1.1e-289 rbsA_4 P import. Responsible for energy coupling to the transport system
NECFGCCN_07057 7.4e-112 S (Lipo)protein
NECFGCCN_07058 5.4e-167 G Periplasmic binding protein LacI transcriptional regulator
NECFGCCN_07059 1.9e-294 glpK3 2.7.1.30 G Belongs to the FGGY kinase family
NECFGCCN_07060 3.3e-172 deoR_1 K transcriptional regulator
NECFGCCN_07061 2.6e-157 tktB 2.2.1.1 G Transketolase
NECFGCCN_07062 4.2e-167 tktA 2.2.1.1 G Transketolase
NECFGCCN_07063 5.4e-110 entD 6.3.2.14 Q Belongs to the P-Pant transferase superfamily
NECFGCCN_07064 0.0 fepA P Receptor
NECFGCCN_07066 5.1e-22 K Transcriptional
NECFGCCN_07067 5.1e-98 slsA Q COG1335 Amidases related to nicotinamidase
NECFGCCN_07068 1.1e-161 yhhW_1 S Belongs to the pirin family
NECFGCCN_07069 2e-166 K transcriptional regulator
NECFGCCN_07070 4.1e-206 livJ E With LivFGHM is involved in the high affinity leucine transport
NECFGCCN_07071 1.5e-225 E Amino acid permease
NECFGCCN_07072 1.8e-237 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NECFGCCN_07073 5.3e-289 gabR_1 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NECFGCCN_07074 5.7e-155 rpoH K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes
NECFGCCN_07075 2.2e-185 ftsX D Part of the ABC transporter FtsEX involved in cellular division
NECFGCCN_07076 3.2e-121 ftsE D cell division ATP-binding protein FtsE
NECFGCCN_07077 1.3e-173 ftsY D Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components
NECFGCCN_07078 3e-110 rsmD 2.1.1.171 L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle
NECFGCCN_07079 4.7e-42 yhhL S Membrane
NECFGCCN_07080 3.7e-39 yhhM S Protein of unknown function (DUF2500)
NECFGCCN_07081 2.4e-110 yhhN S membrane
NECFGCCN_07082 0.0 zntA 3.6.3.3, 3.6.3.5 P P-type atpase
NECFGCCN_07083 1.6e-38 tusA O Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin
NECFGCCN_07084 9.6e-118 yhhQ U Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NECFGCCN_07085 4.5e-92 dcrB S dcrb protein
NECFGCCN_07086 3.1e-215 yhhS EGP MFS-type transporter
NECFGCCN_07087 6.7e-166 yhhT T permease
NECFGCCN_07088 3.9e-63 arnF U Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane
NECFGCCN_07089 1.1e-56 arnE U Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane
NECFGCCN_07090 2.9e-304 arnT 2.4.2.43 M Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides
NECFGCCN_07091 2e-174 arnD G Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides
NECFGCCN_07092 0.0 arnA 1.1.1.305, 2.1.2.13, 2.1.2.9, 5.1.3.2 GJM Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides
NECFGCCN_07093 6.5e-179 arnC 2.4.2.53 GT2 M Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides
NECFGCCN_07094 1.6e-216 arnB 2.6.1.87 E Belongs to the DegT DnrJ EryC1 family
NECFGCCN_07095 3.8e-98 padC Q Phenolic acid decarboxylase
NECFGCCN_07096 5.4e-153 IV02_08490 K transcriptional regulator
NECFGCCN_07097 2e-286 nikA E nickel ABC transporter
NECFGCCN_07098 4.2e-159 nikB P transport
NECFGCCN_07099 1.4e-150 nikC 3.6.3.24 P transport
NECFGCCN_07100 8.4e-134 nikD 3.6.3.24 P Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system
NECFGCCN_07101 6.5e-137 nikE 3.6.3.24 P Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system
NECFGCCN_07102 2.7e-67 nikR K Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel
NECFGCCN_07103 2.2e-177 mgtE 3.6.1.1 P Acts as a magnesium transporter
NECFGCCN_07104 1.6e-227 yhiN S HI0933 family
NECFGCCN_07105 4.6e-269 pitA P phosphate transporter
NECFGCCN_07106 2.8e-57 uspB S ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
NECFGCCN_07107 6e-76 uspA T Required for resistance to DNA-damaging agents
NECFGCCN_07108 4.4e-111 dtpB U Proton-dependent permease that transports di- and tripeptides
NECFGCCN_07109 2e-71 S Region found in RelA / SpoT proteins
NECFGCCN_07110 5.6e-17
NECFGCCN_07111 6.3e-36 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NECFGCCN_07112 2.4e-12 S PcfK-like protein
NECFGCCN_07113 4.4e-177 ghrA 1.1.1.79, 1.1.1.81 EH D-isomer specific 2-hydroxyacid dehydrogenase
NECFGCCN_07114 3.8e-139 ycdX E Belongs to the PHP family
NECFGCCN_07115 9.5e-103 ycdY S chaperone
NECFGCCN_07116 4e-81 ycdZ S Protein of unknown function (DUF1097)
NECFGCCN_07117 8.8e-90 ymdB S Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation
NECFGCCN_07118 1.2e-95 K transcriptional regulator
NECFGCCN_07119 4.6e-216 mdoC I Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane
NECFGCCN_07120 1.3e-306 mdoG P Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NECFGCCN_07121 0.0 mdoH GT2 M Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NECFGCCN_07122 5.4e-36 yceK S (Lipo)protein
NECFGCCN_07123 2.2e-66 msyB S SecY secA suppressor protein
NECFGCCN_07124 3.8e-213 mdtG EGP Major facilitator Superfamily
NECFGCCN_07125 2e-182 lpxL 2.3.1.241, 2.3.1.242, 2.3.1.243 M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)
NECFGCCN_07126 4.7e-207 yceA S Belongs to the UPF0176 family
NECFGCCN_07127 6.3e-09 yceO S Protein of unknown function (DUF2770)
NECFGCCN_07128 3.9e-212 solA 1.5.3.1 E Belongs to the MSOX MTOX family. MTOX subfamily
NECFGCCN_07129 2.8e-41 bssS S disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
NECFGCCN_07130 1.3e-38 dinI S SOS response
NECFGCCN_07131 2.4e-200 pyrC 3.5.2.3 F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate
NECFGCCN_07132 1.9e-95 yceB S Lipoprotein
NECFGCCN_07133 2.6e-222 mdtH U Multidrug resistance protein mdtH
NECFGCCN_07134 1.6e-111 rimJ 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NECFGCCN_07135 9.8e-115 yceH S Belongs to the UPF0502 family
NECFGCCN_07136 1.4e-170 mviM 1.1.1.18, 1.1.1.369 S oxidoreductase
NECFGCCN_07137 5.1e-271 murJ S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NECFGCCN_07138 1.9e-164 ynfM_3 EGP Major facilitator Superfamily
NECFGCCN_07139 6.2e-171 ttdR K transcriptional regulator
NECFGCCN_07140 0.0 rne 3.1.26.12 J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs
NECFGCCN_07141 2.6e-183 rluC 5.4.99.24 J Responsible for synthesis of pseudouridine from uracil
NECFGCCN_07142 2.6e-103 maf 1.1.1.25, 2.1.1.190 D Maf-like protein
NECFGCCN_07143 9.3e-92 yceD S metal-binding, possibly nucleic acid-binding protein
NECFGCCN_07144 3.6e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NECFGCCN_07145 4.6e-208 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NECFGCCN_07146 4.7e-174 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NECFGCCN_07147 2.5e-164 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NECFGCCN_07148 3.6e-126 IQ reductase
NECFGCCN_07149 8.9e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NECFGCCN_07150 1.9e-231 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NECFGCCN_07151 1.4e-150 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NECFGCCN_07152 1.1e-189 mltG F Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NECFGCCN_07153 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NECFGCCN_07154 1.5e-186 holB 2.7.7.7 L dna polymerase iii
NECFGCCN_07155 1.3e-148 ycfH L TatD family
NECFGCCN_07156 1.3e-265 ptsG 2.7.1.192, 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Phosphotransferase System
NECFGCCN_07157 1.3e-60 hinT FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NECFGCCN_07158 1e-60 ycfL S cellular response to DNA damage stimulus
NECFGCCN_07159 5.5e-94 lpoB M Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
NECFGCCN_07160 5e-148 thiK 2.7.1.89 M Catalyzes the phosphorylation of thiamine to thiamine phosphate
NECFGCCN_07161 1.7e-190 nagZ 2.7.8.7, 3.2.1.21, 3.2.1.52 GH3 G Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides
NECFGCCN_07162 2.2e-104 ycfP S Belongs to the UPF0227 family
NECFGCCN_07163 1e-248 ndh 1.6.99.3 C NADH dehydrogenase
NECFGCCN_07164 3.4e-73 ycfJ S Outer Membrane Lipoprotein
NECFGCCN_07165 0.0 iutA H Receptor
NECFGCCN_07166 1.9e-110 ycfQ K Transcriptional regulator
NECFGCCN_07167 4.7e-36 bhsA S Multiple stress resistance protein BhsA
NECFGCCN_07168 1.8e-178 ycfS M ErfK YbiS YcfS YnhG family protein
NECFGCCN_07169 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NECFGCCN_07170 4.6e-203 lolC M Lipoprotein releasing system transmembrane protein
NECFGCCN_07171 5.9e-126 lolD V Part of the ABC transporter complex LolCDE involved in the translocation of
NECFGCCN_07172 5.6e-228 lolE M Lipoprotein releasing system transmembrane protein
NECFGCCN_07173 1.2e-174 nagK 2.7.1.4, 2.7.1.59 F Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P
NECFGCCN_07174 5.5e-155 cobB K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NECFGCCN_07176 3.3e-175 lsrR K Transcriptional regulator
NECFGCCN_07177 3.7e-148 tpiA 2.7.2.3, 5.1.3.39, 5.3.1.1, 5.3.1.33 G triose-phosphate isomerase
NECFGCCN_07178 1.9e-194 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NECFGCCN_07179 0.0 2.7.1.198, 2.7.1.219, 2.7.1.220 G PTS system glucitol sorbitol-specific
NECFGCCN_07180 3.6e-172 kdgT4 U The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NECFGCCN_07181 1.1e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NECFGCCN_07182 2.7e-79 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NECFGCCN_07183 6.9e-178 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)