ORF_ID e_value Gene_name EC_number CAZy COGs Description
NBLEGCCO_00001 4e-167 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NBLEGCCO_00002 2.2e-174 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NBLEGCCO_00003 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NBLEGCCO_00004 5.5e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NBLEGCCO_00005 7.3e-71 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NBLEGCCO_00006 1.2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NBLEGCCO_00007 1.2e-171 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBLEGCCO_00008 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NBLEGCCO_00009 9.4e-217 patA 2.6.1.1 E Aminotransferase
NBLEGCCO_00010 5.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NBLEGCCO_00011 9.6e-226 ktrB P Potassium uptake protein
NBLEGCCO_00012 4.4e-118 ktrA P domain protein
NBLEGCCO_00013 1.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
NBLEGCCO_00014 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NBLEGCCO_00015 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NBLEGCCO_00017 0.0 dnaE 2.7.7.7 L DNA polymerase
NBLEGCCO_00018 8.3e-268 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NBLEGCCO_00019 1.6e-168 cvfB S S1 domain
NBLEGCCO_00020 2.4e-132 xerD D recombinase XerD
NBLEGCCO_00021 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NBLEGCCO_00022 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NBLEGCCO_00023 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NBLEGCCO_00024 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NBLEGCCO_00025 3.7e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NBLEGCCO_00026 1.3e-26
NBLEGCCO_00027 6.8e-86 K Helix-turn-helix XRE-family like proteins
NBLEGCCO_00028 6.1e-29 S Domain of unknown function (DUF4767)
NBLEGCCO_00029 1.9e-44 S Tautomerase enzyme
NBLEGCCO_00030 3.6e-19 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NBLEGCCO_00031 3.9e-119 pnb C nitroreductase
NBLEGCCO_00032 6.5e-81 S Alpha/beta hydrolase family
NBLEGCCO_00033 4.8e-79 ctsR K Belongs to the CtsR family
NBLEGCCO_00034 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NBLEGCCO_00035 5.4e-104 K Bacterial regulatory proteins, tetR family
NBLEGCCO_00036 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBLEGCCO_00037 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBLEGCCO_00038 5.6e-135 puuD S peptidase C26
NBLEGCCO_00039 1.1e-184 ykiI
NBLEGCCO_00040 2.1e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
NBLEGCCO_00041 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NBLEGCCO_00042 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NBLEGCCO_00043 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NBLEGCCO_00044 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NBLEGCCO_00045 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NBLEGCCO_00046 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
NBLEGCCO_00047 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NBLEGCCO_00048 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NBLEGCCO_00049 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NBLEGCCO_00050 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NBLEGCCO_00051 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NBLEGCCO_00052 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NBLEGCCO_00053 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
NBLEGCCO_00054 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NBLEGCCO_00055 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NBLEGCCO_00056 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NBLEGCCO_00057 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NBLEGCCO_00058 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBLEGCCO_00059 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NBLEGCCO_00060 1.1e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NBLEGCCO_00061 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NBLEGCCO_00062 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NBLEGCCO_00063 5.5e-23 rpmD J Ribosomal protein L30
NBLEGCCO_00064 2.1e-65 rplO J Binds to the 23S rRNA
NBLEGCCO_00065 5.8e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NBLEGCCO_00066 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NBLEGCCO_00067 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NBLEGCCO_00068 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NBLEGCCO_00069 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NBLEGCCO_00070 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NBLEGCCO_00071 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBLEGCCO_00072 2.8e-61 rplQ J Ribosomal protein L17
NBLEGCCO_00073 4.6e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBLEGCCO_00074 2e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBLEGCCO_00075 5.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NBLEGCCO_00076 2.2e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NBLEGCCO_00077 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NBLEGCCO_00078 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NBLEGCCO_00079 1.6e-189 S interspecies interaction between organisms
NBLEGCCO_00080 1.2e-138 IQ reductase
NBLEGCCO_00081 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NBLEGCCO_00082 3.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NBLEGCCO_00083 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NBLEGCCO_00084 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NBLEGCCO_00085 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NBLEGCCO_00086 1.3e-64 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NBLEGCCO_00087 6e-91 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NBLEGCCO_00088 1.6e-25 yitW S Iron-sulfur cluster assembly protein
NBLEGCCO_00089 1.3e-24 M domain, Protein
NBLEGCCO_00090 6.5e-109 lutB C 4Fe-4S dicluster domain
NBLEGCCO_00091 7.4e-30 lutB C 4Fe-4S dicluster domain
NBLEGCCO_00092 1.9e-30 lutA C Cysteine-rich domain
NBLEGCCO_00093 2.5e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NBLEGCCO_00094 9.4e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NBLEGCCO_00095 2e-36 ynzC S UPF0291 protein
NBLEGCCO_00096 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
NBLEGCCO_00097 2.6e-112 plsC 2.3.1.51 I Acyltransferase
NBLEGCCO_00098 3.2e-133 yabB 2.1.1.223 L Methyltransferase small domain
NBLEGCCO_00099 2.3e-47 yazA L GIY-YIG catalytic domain protein
NBLEGCCO_00100 3.3e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
NBLEGCCO_00101 1.2e-152 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NBLEGCCO_00102 3.8e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NBLEGCCO_00103 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NBLEGCCO_00104 1e-139 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NBLEGCCO_00105 1.8e-134 cdsA 2.7.7.41 I Belongs to the CDS family
NBLEGCCO_00106 1.6e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NBLEGCCO_00107 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NBLEGCCO_00108 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBLEGCCO_00109 3.7e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine
NBLEGCCO_00110 1.3e-134 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
NBLEGCCO_00111 9.9e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NBLEGCCO_00112 1.5e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NBLEGCCO_00113 9.8e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NBLEGCCO_00114 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NBLEGCCO_00115 5.6e-83 rimP J Required for maturation of 30S ribosomal subunits
NBLEGCCO_00116 7e-223 nusA K Participates in both transcription termination and antitermination
NBLEGCCO_00117 9e-47 ylxR K Protein of unknown function (DUF448)
NBLEGCCO_00118 2.7e-49 ylxQ J ribosomal protein
NBLEGCCO_00119 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NBLEGCCO_00120 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NBLEGCCO_00121 1.5e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NBLEGCCO_00122 2.4e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NBLEGCCO_00123 3.3e-55 tlpA2 L Transposase IS200 like
NBLEGCCO_00124 4.7e-252 yifK E Amino acid permease
NBLEGCCO_00126 4e-133 pnuC H nicotinamide mononucleotide transporter
NBLEGCCO_00127 8.6e-204 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NBLEGCCO_00128 4.4e-123 sirR K iron dependent repressor
NBLEGCCO_00129 1.1e-29 cspA K Cold shock protein
NBLEGCCO_00130 6.5e-82 thrE S Putative threonine/serine exporter
NBLEGCCO_00131 1.4e-28 thrE S Putative threonine/serine exporter
NBLEGCCO_00132 6.9e-81 S Threonine/Serine exporter, ThrE
NBLEGCCO_00133 2.2e-114 lssY 3.6.1.27 I phosphatase
NBLEGCCO_00134 1.2e-154 I alpha/beta hydrolase fold
NBLEGCCO_00136 9.6e-267 lysP E amino acid
NBLEGCCO_00137 2.3e-116 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NBLEGCCO_00139 1.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NBLEGCCO_00140 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NBLEGCCO_00141 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NBLEGCCO_00142 1.6e-174 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NBLEGCCO_00143 7.3e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NBLEGCCO_00144 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NBLEGCCO_00145 7e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NBLEGCCO_00146 3.8e-57 S Domain of unknown function (DUF4440)
NBLEGCCO_00147 8.6e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBLEGCCO_00148 2.3e-139 tesE Q hydratase
NBLEGCCO_00149 7.6e-97 ywrO S Flavodoxin-like fold
NBLEGCCO_00150 1.8e-41 S Protein conserved in bacteria
NBLEGCCO_00151 8.9e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NBLEGCCO_00152 3.8e-50 S Sugar efflux transporter for intercellular exchange
NBLEGCCO_00153 0.0 asnB 6.3.5.4 E Aluminium induced protein
NBLEGCCO_00154 5.7e-116 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NBLEGCCO_00155 8e-12
NBLEGCCO_00156 1.6e-180 scrR3 K Transcriptional regulator, LacI family
NBLEGCCO_00157 3.8e-78 F Nucleoside 2-deoxyribosyltransferase
NBLEGCCO_00158 6.7e-170 GK ROK family
NBLEGCCO_00159 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NBLEGCCO_00160 3.2e-96 ymfM S Helix-turn-helix domain
NBLEGCCO_00161 2.4e-250 ymfH S Peptidase M16
NBLEGCCO_00162 7.5e-228 ymfF S Peptidase M16 inactive domain protein
NBLEGCCO_00163 3.5e-160 aatB ET ABC transporter substrate-binding protein
NBLEGCCO_00164 2.2e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NBLEGCCO_00165 1.4e-108 glnP P ABC transporter permease
NBLEGCCO_00166 2.5e-92 mreD M rod shape-determining protein MreD
NBLEGCCO_00167 2.4e-145 mreC M Involved in formation and maintenance of cell shape
NBLEGCCO_00168 1.9e-181 mreB D cell shape determining protein MreB
NBLEGCCO_00169 9.4e-115 radC L DNA repair protein
NBLEGCCO_00170 4.4e-118 glcU U sugar transport
NBLEGCCO_00171 1.3e-85 L PFAM transposase, IS4 family protein
NBLEGCCO_00172 1.9e-56 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NBLEGCCO_00173 1.2e-111 nss M transferase activity, transferring glycosyl groups
NBLEGCCO_00174 1.3e-88 secY2 U SecY translocase
NBLEGCCO_00175 1.4e-103 asp1 S Accessory Sec system protein Asp1
NBLEGCCO_00176 1.4e-130 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
NBLEGCCO_00177 1.9e-19 asp3 S Accessory Sec secretory system ASP3
NBLEGCCO_00178 6.4e-273 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NBLEGCCO_00180 4.3e-166 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NBLEGCCO_00181 4.4e-130 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NBLEGCCO_00182 4.6e-115 yecS E ABC transporter permease
NBLEGCCO_00183 1e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
NBLEGCCO_00184 1.3e-105 XK27_02070 S Nitroreductase family
NBLEGCCO_00185 1.2e-70 rnhA 3.1.26.4 L Ribonuclease HI
NBLEGCCO_00186 3.7e-70 esbA S Family of unknown function (DUF5322)
NBLEGCCO_00187 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NBLEGCCO_00188 3.4e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NBLEGCCO_00189 4e-206 carA 6.3.5.5 F Belongs to the CarA family
NBLEGCCO_00190 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NBLEGCCO_00191 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NBLEGCCO_00192 1.3e-45 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NBLEGCCO_00193 1.4e-136 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NBLEGCCO_00194 1.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NBLEGCCO_00197 9.8e-77
NBLEGCCO_00198 2.8e-54 azlD E Branched-chain amino acid transport
NBLEGCCO_00199 6.5e-26 azlC E azaleucine resistance protein AzlC
NBLEGCCO_00202 9.8e-77
NBLEGCCO_00203 9.7e-134 manR K PRD domain
NBLEGCCO_00204 3.3e-18 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBLEGCCO_00205 2.6e-53 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBLEGCCO_00206 2.5e-39 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
NBLEGCCO_00207 1.4e-126 G Phosphotransferase System
NBLEGCCO_00208 1.1e-108 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
NBLEGCCO_00209 1.6e-123 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBLEGCCO_00210 1.1e-262 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBLEGCCO_00211 1.9e-109 pncA Q Isochorismatase family
NBLEGCCO_00212 8.7e-125 3.6.1.13, 3.6.1.55 F NUDIX domain
NBLEGCCO_00213 0.0 clpE O Belongs to the ClpA ClpB family
NBLEGCCO_00215 8e-39 ptsH G phosphocarrier protein HPR
NBLEGCCO_00216 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBLEGCCO_00217 1.9e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NBLEGCCO_00218 2.1e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
NBLEGCCO_00219 2.7e-180 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBLEGCCO_00220 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
NBLEGCCO_00221 7.8e-178 fecB P Periplasmic binding protein
NBLEGCCO_00222 4.2e-272 sufB O assembly protein SufB
NBLEGCCO_00223 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
NBLEGCCO_00224 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NBLEGCCO_00225 5.8e-244 sufD O FeS assembly protein SufD
NBLEGCCO_00226 3.6e-143 sufC O FeS assembly ATPase SufC
NBLEGCCO_00227 3.9e-33 feoA P FeoA domain
NBLEGCCO_00228 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NBLEGCCO_00229 6.7e-23 S Virus attachment protein p12 family
NBLEGCCO_00230 2.7e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NBLEGCCO_00231 2.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NBLEGCCO_00232 2.2e-32 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NBLEGCCO_00233 2.3e-93 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NBLEGCCO_00234 1.9e-34 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NBLEGCCO_00235 3.8e-37 S CRISPR-associated protein (Cas_Csn2)
NBLEGCCO_00236 4.2e-17 L PFAM transposase IS3 IS911 family protein
NBLEGCCO_00237 3.1e-40 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NBLEGCCO_00238 6e-74 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NBLEGCCO_00239 6.7e-49 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NBLEGCCO_00240 8e-71 ydjP I Alpha/beta hydrolase family
NBLEGCCO_00241 3.9e-107 L Integrase
NBLEGCCO_00242 3.3e-45 K transcriptional regulator
NBLEGCCO_00243 1.3e-66 GM NmrA-like family
NBLEGCCO_00244 9.1e-27 C Flavodoxin
NBLEGCCO_00245 1.1e-09 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NBLEGCCO_00246 8.6e-53 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NBLEGCCO_00247 4.2e-74 O OsmC-like protein
NBLEGCCO_00248 4.7e-76 K Transcriptional regulator
NBLEGCCO_00249 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
NBLEGCCO_00250 1.8e-108 proWZ P ABC transporter permease
NBLEGCCO_00251 9.3e-141 proV E ABC transporter, ATP-binding protein
NBLEGCCO_00252 6.6e-100 proW P ABC transporter, permease protein
NBLEGCCO_00253 5e-81 3.4.11.9 V site-specific DNA-methyltransferase (adenine-specific) activity
NBLEGCCO_00254 1e-143 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NBLEGCCO_00255 5.5e-145 C Zinc-binding dehydrogenase
NBLEGCCO_00256 1.8e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
NBLEGCCO_00257 9.4e-225 4.4.1.8 E Aminotransferase, class I
NBLEGCCO_00258 2.1e-179 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NBLEGCCO_00259 1.5e-200 xerS L Belongs to the 'phage' integrase family
NBLEGCCO_00260 4e-62 ywkB S Membrane transport protein
NBLEGCCO_00261 4.3e-58 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
NBLEGCCO_00262 3.7e-140 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
NBLEGCCO_00263 2.8e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NBLEGCCO_00264 2.6e-80 hmpT S ECF-type riboflavin transporter, S component
NBLEGCCO_00265 5.1e-167 1.1.1.346 C Aldo keto reductase
NBLEGCCO_00266 3.4e-161 S DUF218 domain
NBLEGCCO_00269 1.3e-93 K Acetyltransferase (GNAT) domain
NBLEGCCO_00270 1.1e-163 I alpha/beta hydrolase fold
NBLEGCCO_00271 5.7e-72 S Phage minor capsid protein 2
NBLEGCCO_00272 7.5e-34 S Phage minor capsid protein 2
NBLEGCCO_00275 9.4e-214 2.6.1.1 E Aminotransferase
NBLEGCCO_00276 4.6e-81 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
NBLEGCCO_00277 1.9e-51 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
NBLEGCCO_00278 3.4e-92 EGP Sugar (and other) transporter
NBLEGCCO_00279 1.6e-122 EGP Sugar (and other) transporter
NBLEGCCO_00280 4.6e-97 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
NBLEGCCO_00281 1.2e-91 S Fic/DOC family
NBLEGCCO_00282 4.4e-71 yncA 2.3.1.79 S Maltose acetyltransferase
NBLEGCCO_00283 2e-104 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NBLEGCCO_00284 4.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NBLEGCCO_00285 1.3e-263 arcD E Amino acid permease
NBLEGCCO_00286 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NBLEGCCO_00287 1.5e-123 pgm3 G phosphoglycerate mutase family
NBLEGCCO_00288 1.7e-146 qorB 1.6.5.2 GM NmrA-like family
NBLEGCCO_00289 5.6e-96 L PFAM Integrase catalytic region
NBLEGCCO_00291 7.4e-251 yclK 2.7.13.3 T Histidine kinase
NBLEGCCO_00292 9.7e-132 K response regulator
NBLEGCCO_00295 6.1e-44 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NBLEGCCO_00296 2.8e-40 ulaB 2.7.1.194 G Phosphotransferase system galactitol-specific IIB component
NBLEGCCO_00297 3.7e-193 ulaA 2.7.1.194 S PTS system sugar-specific permease component
NBLEGCCO_00298 2e-259 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NBLEGCCO_00299 7.8e-123 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NBLEGCCO_00300 2e-135 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
NBLEGCCO_00301 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NBLEGCCO_00302 2.1e-244 glpT G Major Facilitator Superfamily
NBLEGCCO_00303 9.7e-130 qmcA O prohibitin homologues
NBLEGCCO_00305 3.1e-75 uspA T universal stress protein
NBLEGCCO_00306 1.8e-58
NBLEGCCO_00307 2.5e-19
NBLEGCCO_00308 2.1e-157
NBLEGCCO_00309 8.4e-75 K Transcriptional regulator
NBLEGCCO_00310 1.1e-183 D Alpha beta
NBLEGCCO_00311 3.9e-72 O OsmC-like protein
NBLEGCCO_00312 1.5e-191 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
NBLEGCCO_00313 0.0 yjcE P Sodium proton antiporter
NBLEGCCO_00314 1.8e-13 yvlA
NBLEGCCO_00315 2.4e-113 P Cobalt transport protein
NBLEGCCO_00316 2.8e-252 cbiO1 S ABC transporter, ATP-binding protein
NBLEGCCO_00317 2.3e-99 S ABC-type cobalt transport system, permease component
NBLEGCCO_00318 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
NBLEGCCO_00319 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NBLEGCCO_00320 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
NBLEGCCO_00321 3.1e-31 copZ P Heavy-metal-associated domain
NBLEGCCO_00322 2.2e-99 dps P Belongs to the Dps family
NBLEGCCO_00323 1.1e-105 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NBLEGCCO_00324 1.9e-78 K FR47-like protein
NBLEGCCO_00325 1.8e-80 L Phage integrase family
NBLEGCCO_00326 6.3e-243 ganB 3.2.1.89 G arabinogalactan
NBLEGCCO_00327 1.6e-84 ydcK S Belongs to the SprT family
NBLEGCCO_00328 0.0 yhgF K Tex-like protein N-terminal domain protein
NBLEGCCO_00329 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NBLEGCCO_00330 7.9e-282 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NBLEGCCO_00331 5.9e-126 gntR1 K UbiC transcription regulator-associated domain protein
NBLEGCCO_00332 1.3e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NBLEGCCO_00333 4e-113
NBLEGCCO_00336 2.6e-147 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NBLEGCCO_00337 5.8e-155 ykuT M mechanosensitive ion channel
NBLEGCCO_00338 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NBLEGCCO_00339 1.7e-67
NBLEGCCO_00340 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NBLEGCCO_00341 5.5e-181 ccpA K catabolite control protein A
NBLEGCCO_00342 1.3e-79
NBLEGCCO_00343 3.7e-134 yebC K Transcriptional regulatory protein
NBLEGCCO_00344 3.9e-81 mltD CBM50 M PFAM NLP P60 protein
NBLEGCCO_00345 3.8e-140 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
NBLEGCCO_00346 7.4e-177 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
NBLEGCCO_00347 8.6e-176 comGA NU Type II IV secretion system protein
NBLEGCCO_00348 8.7e-158 comGB NU type II secretion system
NBLEGCCO_00349 1.5e-221 S Recombinase
NBLEGCCO_00350 6.6e-36
NBLEGCCO_00353 3.3e-21 K sequence-specific DNA binding
NBLEGCCO_00354 4.5e-14 K Helix-turn-helix XRE-family like proteins
NBLEGCCO_00355 1.2e-132 K Phage regulatory protein
NBLEGCCO_00356 3.9e-21
NBLEGCCO_00359 6e-164 S DNA metabolic process
NBLEGCCO_00360 1.6e-165 S PDDEXK-like domain of unknown function (DUF3799)
NBLEGCCO_00361 1.8e-38 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NBLEGCCO_00362 1.9e-130 S calcium ion binding
NBLEGCCO_00363 1.1e-43 dnaC 3.4.21.53 L IstB-like ATP binding protein
NBLEGCCO_00366 1.4e-40 rusA L Endodeoxyribonuclease RusA
NBLEGCCO_00367 1.2e-07
NBLEGCCO_00368 2.2e-09 K Transcriptional regulator
NBLEGCCO_00375 1.4e-52 K Domain of unknown function (DUF4417)
NBLEGCCO_00377 2.5e-49 S Terminase small subunit
NBLEGCCO_00378 7.6e-175 S Pfam:Terminase_3C
NBLEGCCO_00379 1.1e-158 S Phage portal protein, SPP1 Gp6-like
NBLEGCCO_00380 3.9e-90 M Phage minor capsid protein 2
NBLEGCCO_00381 1.6e-26 S Phage minor structural protein GP20
NBLEGCCO_00382 1.8e-84
NBLEGCCO_00383 5.9e-11
NBLEGCCO_00384 2.1e-31 S Minor capsid protein
NBLEGCCO_00385 8.5e-18 S Minor capsid protein
NBLEGCCO_00386 1.1e-07
NBLEGCCO_00387 2.2e-20
NBLEGCCO_00389 2.7e-42 S Bacteriophage Gp15 protein
NBLEGCCO_00390 2.9e-235 S peptidoglycan catabolic process
NBLEGCCO_00391 4.1e-118 S Phage tail protein
NBLEGCCO_00392 3.9e-40 S Prophage endopeptidase tail
NBLEGCCO_00393 3.6e-47 spoIVFA GT2,GT4 D peptidase
NBLEGCCO_00396 4.4e-30 S GDSL-like Lipase/Acylhydrolase
NBLEGCCO_00397 7.7e-16
NBLEGCCO_00399 2.5e-10
NBLEGCCO_00400 3.3e-24 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NBLEGCCO_00401 7.9e-206 S peptidoglycan catabolic process
NBLEGCCO_00404 1.4e-38 comGC U competence protein ComGC
NBLEGCCO_00405 5e-15 NU general secretion pathway protein
NBLEGCCO_00407 1.3e-14
NBLEGCCO_00409 4.3e-158 ytxK 2.1.1.72 L N-6 DNA Methylase
NBLEGCCO_00410 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBLEGCCO_00411 2.1e-106 S Calcineurin-like phosphoesterase
NBLEGCCO_00412 5.6e-92 yutD S Protein of unknown function (DUF1027)
NBLEGCCO_00413 7.3e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NBLEGCCO_00414 7.5e-25 S Protein of unknown function (DUF1461)
NBLEGCCO_00415 1.9e-102 dedA S SNARE-like domain protein
NBLEGCCO_00416 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
NBLEGCCO_00417 4.7e-311 ubiB S ABC1 family
NBLEGCCO_00418 3.3e-103 wecD3 K Acetyltransferase (GNAT) family
NBLEGCCO_00419 4.9e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NBLEGCCO_00420 1.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBLEGCCO_00421 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBLEGCCO_00422 9.9e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NBLEGCCO_00423 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NBLEGCCO_00424 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NBLEGCCO_00425 1.3e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NBLEGCCO_00426 5e-211 EG GntP family permease
NBLEGCCO_00427 2.3e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBLEGCCO_00428 1.5e-211 iscS2 2.8.1.7 E Aminotransferase class V
NBLEGCCO_00429 2.2e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NBLEGCCO_00430 7e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NBLEGCCO_00431 5.5e-09
NBLEGCCO_00432 3.1e-145 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NBLEGCCO_00433 5.3e-133 S Membrane
NBLEGCCO_00434 3.7e-75 4.4.1.5 E Glyoxalase
NBLEGCCO_00435 7.2e-83 yueI S Protein of unknown function (DUF1694)
NBLEGCCO_00436 4.9e-235 rarA L recombination factor protein RarA
NBLEGCCO_00438 2.3e-81 usp6 T universal stress protein
NBLEGCCO_00439 2.4e-150 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NBLEGCCO_00440 1.5e-14 K helix_turn_helix multiple antibiotic resistance protein
NBLEGCCO_00441 4.2e-08 L Transposase
NBLEGCCO_00443 6.8e-130 K response regulator
NBLEGCCO_00444 0.0 vicK 2.7.13.3 T Histidine kinase
NBLEGCCO_00445 9e-237 yycH S YycH protein
NBLEGCCO_00446 2.8e-140 yycI S YycH protein
NBLEGCCO_00447 2.3e-153 vicX 3.1.26.11 S domain protein
NBLEGCCO_00448 2.5e-207 htrA 3.4.21.107 O serine protease
NBLEGCCO_00449 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NBLEGCCO_00450 4.8e-70 K Transcriptional regulator
NBLEGCCO_00451 2.4e-175 malR K Transcriptional regulator, LacI family
NBLEGCCO_00452 1.3e-249 malT G Major Facilitator
NBLEGCCO_00453 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NBLEGCCO_00454 2e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NBLEGCCO_00455 1.6e-89 ysdA CP transmembrane transport
NBLEGCCO_00456 2.2e-72 natA S ABC transporter, ATP-binding protein
NBLEGCCO_00457 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NBLEGCCO_00458 1e-110 ypsA S Belongs to the UPF0398 family
NBLEGCCO_00459 8.6e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NBLEGCCO_00460 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NBLEGCCO_00461 3.7e-160 EG EamA-like transporter family
NBLEGCCO_00462 3.1e-192 C Aldo keto reductase family protein
NBLEGCCO_00463 1.3e-121 ypuA S Protein of unknown function (DUF1002)
NBLEGCCO_00464 4.7e-134 dnaD L DnaD domain protein
NBLEGCCO_00465 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NBLEGCCO_00466 8.1e-88 ypmB S Protein conserved in bacteria
NBLEGCCO_00467 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NBLEGCCO_00468 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NBLEGCCO_00469 7e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NBLEGCCO_00470 1.5e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NBLEGCCO_00471 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NBLEGCCO_00472 9e-96 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NBLEGCCO_00473 1.6e-120 L transposase, IS605 OrfB family
NBLEGCCO_00474 2.3e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NBLEGCCO_00475 3.9e-232 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NBLEGCCO_00476 4.2e-286 thrC 4.2.3.1 E Threonine synthase
NBLEGCCO_00477 2.5e-86 azlC E azaleucine resistance protein AzlC
NBLEGCCO_00478 7.8e-126 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
NBLEGCCO_00479 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NBLEGCCO_00480 2.6e-42
NBLEGCCO_00481 2.6e-297 ytgP S Polysaccharide biosynthesis protein
NBLEGCCO_00482 5.8e-61 3.2.1.23 S Domain of unknown function DUF302
NBLEGCCO_00483 5.8e-31 L PFAM Integrase catalytic region
NBLEGCCO_00484 6.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBLEGCCO_00485 1.3e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NBLEGCCO_00486 9e-176
NBLEGCCO_00487 1.4e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NBLEGCCO_00488 9.5e-52 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NBLEGCCO_00489 0.0 copA 3.6.3.54 P P-type ATPase
NBLEGCCO_00490 3.6e-45 EGP Major facilitator Superfamily
NBLEGCCO_00491 9e-77 EGP Major facilitator Superfamily
NBLEGCCO_00492 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
NBLEGCCO_00493 6.5e-45 S Core-2/I-Branching enzyme
NBLEGCCO_00494 1.5e-83 S polysaccharide biosynthetic process
NBLEGCCO_00495 5.7e-36 MA20_43635 M Capsular polysaccharide synthesis protein
NBLEGCCO_00496 5e-37 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
NBLEGCCO_00498 2.6e-88 lsgF M Glycosyl transferase family 2
NBLEGCCO_00499 1.1e-91 capM M Bacterial sugar transferase
NBLEGCCO_00500 9.7e-138 ywqE 3.1.3.48 GM PHP domain protein
NBLEGCCO_00501 9.4e-114 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NBLEGCCO_00502 1.1e-130 epsB M biosynthesis protein
NBLEGCCO_00503 7.8e-159 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NBLEGCCO_00504 1.7e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NBLEGCCO_00505 3.8e-134 XK27_01040 S Protein of unknown function (DUF1129)
NBLEGCCO_00506 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NBLEGCCO_00507 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
NBLEGCCO_00508 8e-146 spo0J K Belongs to the ParB family
NBLEGCCO_00509 6.2e-155 noc K Belongs to the ParB family
NBLEGCCO_00510 6.9e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NBLEGCCO_00511 4.9e-144 rihC 3.2.2.1 F Nucleoside
NBLEGCCO_00512 3.2e-212 nupG F Nucleoside transporter
NBLEGCCO_00513 1.3e-249 cycA E Amino acid permease
NBLEGCCO_00514 1.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NBLEGCCO_00515 3.7e-223 glnP P ABC transporter
NBLEGCCO_00517 1.3e-187 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NBLEGCCO_00519 2.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NBLEGCCO_00520 9.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NBLEGCCO_00521 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NBLEGCCO_00522 1.7e-40 rpmE2 J Ribosomal protein L31
NBLEGCCO_00523 2.7e-121 mdtG EGP Major facilitator Superfamily
NBLEGCCO_00524 4.6e-21 mdtG EGP Major facilitator Superfamily
NBLEGCCO_00525 4.7e-123 srtA 3.4.22.70 M sortase family
NBLEGCCO_00526 1.4e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NBLEGCCO_00527 2.5e-87 lemA S LemA family
NBLEGCCO_00528 2.7e-155 htpX O Belongs to the peptidase M48B family
NBLEGCCO_00529 2e-258 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NBLEGCCO_00530 8.6e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NBLEGCCO_00531 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NBLEGCCO_00532 4.4e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NBLEGCCO_00533 1.9e-56 L Toxic component of a toxin-antitoxin (TA) module
NBLEGCCO_00534 2.6e-112 S (CBS) domain
NBLEGCCO_00535 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NBLEGCCO_00536 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NBLEGCCO_00537 1.6e-39 yabO J S4 domain protein
NBLEGCCO_00538 1.5e-56 divIC D Septum formation initiator
NBLEGCCO_00539 2.5e-86 yabR J RNA binding
NBLEGCCO_00540 6.5e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NBLEGCCO_00541 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NBLEGCCO_00542 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NBLEGCCO_00543 7.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NBLEGCCO_00544 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NBLEGCCO_00545 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NBLEGCCO_00546 5.4e-50 ybjQ S Belongs to the UPF0145 family
NBLEGCCO_00547 4.8e-65 rocF 3.5.3.1, 3.5.3.11 E Arginase family
NBLEGCCO_00548 7.2e-17 rocF 3.5.3.1, 3.5.3.11 E Arginase family
NBLEGCCO_00549 6.4e-58 1.3.1.9 S Nitronate monooxygenase
NBLEGCCO_00550 4.3e-95 1.3.1.9 S Nitronate monooxygenase
NBLEGCCO_00551 1.5e-52 K Helix-turn-helix domain
NBLEGCCO_00552 8e-105 S Domain of unknown function (DUF4767)
NBLEGCCO_00553 1.1e-79
NBLEGCCO_00554 9.3e-09 S Domain of unknown function (DUF4767)
NBLEGCCO_00555 1.3e-81 tlpA2 L Transposase IS200 like
NBLEGCCO_00556 1.1e-259 E Arginine ornithine antiporter
NBLEGCCO_00557 2.3e-220 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NBLEGCCO_00558 7.6e-216 arcT 2.6.1.1 E Aminotransferase
NBLEGCCO_00559 3.2e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NBLEGCCO_00560 2.5e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NBLEGCCO_00561 1.7e-193 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NBLEGCCO_00563 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NBLEGCCO_00564 8.7e-75 marR K Transcriptional regulator, MarR family
NBLEGCCO_00565 2.8e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NBLEGCCO_00566 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBLEGCCO_00567 7.4e-172 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NBLEGCCO_00568 7.8e-129 IQ reductase
NBLEGCCO_00569 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NBLEGCCO_00570 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NBLEGCCO_00571 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NBLEGCCO_00572 4.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NBLEGCCO_00573 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NBLEGCCO_00574 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NBLEGCCO_00575 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NBLEGCCO_00576 9.7e-92 bioY S BioY family
NBLEGCCO_00577 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NBLEGCCO_00578 0.0 uup S ABC transporter, ATP-binding protein
NBLEGCCO_00579 2.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NBLEGCCO_00580 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NBLEGCCO_00581 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NBLEGCCO_00582 0.0 ydaO E amino acid
NBLEGCCO_00583 6.4e-38
NBLEGCCO_00584 2e-112 yvyE 3.4.13.9 S YigZ family
NBLEGCCO_00585 7.7e-252 comFA L Helicase C-terminal domain protein
NBLEGCCO_00586 8e-128 comFC S Competence protein
NBLEGCCO_00587 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NBLEGCCO_00588 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NBLEGCCO_00589 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NBLEGCCO_00590 4.1e-53 KT PspC domain protein
NBLEGCCO_00591 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NBLEGCCO_00592 3.2e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NBLEGCCO_00593 4.7e-162 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NBLEGCCO_00594 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NBLEGCCO_00595 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NBLEGCCO_00596 2.3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NBLEGCCO_00597 1.4e-225 mtnE 2.6.1.83 E Aminotransferase
NBLEGCCO_00598 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NBLEGCCO_00599 6.7e-77 yphH S Cupin domain
NBLEGCCO_00600 2.6e-132 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NBLEGCCO_00601 2.1e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NBLEGCCO_00602 3.4e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NBLEGCCO_00603 4.3e-112 L hmm pf00665
NBLEGCCO_00604 3.6e-241 steT E amino acid
NBLEGCCO_00605 7.1e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NBLEGCCO_00606 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NBLEGCCO_00607 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
NBLEGCCO_00608 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NBLEGCCO_00609 1.2e-60 azlD S branched-chain amino acid
NBLEGCCO_00610 2.8e-141 azlC E AzlC protein
NBLEGCCO_00611 1e-195 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NBLEGCCO_00612 1e-207 hpk31 2.7.13.3 T Histidine kinase
NBLEGCCO_00613 3.6e-123 K response regulator
NBLEGCCO_00614 6.3e-93 S Cupin superfamily (DUF985)
NBLEGCCO_00615 3.7e-57
NBLEGCCO_00616 1.2e-07 S Protein of unknown function (DUF4044)
NBLEGCCO_00617 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NBLEGCCO_00618 1.9e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NBLEGCCO_00619 3.4e-160 rrmA 2.1.1.187 H Methyltransferase
NBLEGCCO_00620 2.4e-192 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NBLEGCCO_00621 3.8e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NBLEGCCO_00622 3.3e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NBLEGCCO_00623 6.2e-117 yjbM 2.7.6.5 S RelA SpoT domain protein
NBLEGCCO_00624 3.9e-113 yjbH Q Thioredoxin
NBLEGCCO_00625 3.8e-198 coiA 3.6.4.12 S Competence protein
NBLEGCCO_00626 2.6e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NBLEGCCO_00627 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NBLEGCCO_00628 7.9e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NBLEGCCO_00631 3.5e-60
NBLEGCCO_00632 2.3e-207 lmrP E Major Facilitator Superfamily
NBLEGCCO_00633 3.1e-243 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NBLEGCCO_00634 1.2e-74 rplI J Binds to the 23S rRNA
NBLEGCCO_00635 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NBLEGCCO_00636 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NBLEGCCO_00637 1.5e-87 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NBLEGCCO_00638 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NBLEGCCO_00639 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NBLEGCCO_00640 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NBLEGCCO_00641 5.3e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NBLEGCCO_00642 2.2e-34 yaaA S S4 domain protein YaaA
NBLEGCCO_00643 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NBLEGCCO_00644 1.5e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NBLEGCCO_00646 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NBLEGCCO_00647 1.9e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NBLEGCCO_00648 9.8e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NBLEGCCO_00649 2.4e-134 jag S R3H domain protein
NBLEGCCO_00650 5.6e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NBLEGCCO_00651 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NBLEGCCO_00652 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBLEGCCO_00653 1.7e-243 fucP G Major Facilitator Superfamily
NBLEGCCO_00654 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NBLEGCCO_00655 2.2e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBLEGCCO_00656 3.2e-170 deoR K sugar-binding domain protein
NBLEGCCO_00657 4.9e-114 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NBLEGCCO_00658 5.8e-199 S Domain of unknown function (DUF4432)
NBLEGCCO_00659 1.2e-174 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBLEGCCO_00660 1.7e-260 G PTS system Galactitol-specific IIC component
NBLEGCCO_00661 1.1e-169 K helix_turn _helix lactose operon repressor
NBLEGCCO_00662 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
NBLEGCCO_00663 1.3e-280 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NBLEGCCO_00664 5.1e-56 ycsI S Protein of unknown function (DUF1445)
NBLEGCCO_00665 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NBLEGCCO_00666 1.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NBLEGCCO_00667 2e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NBLEGCCO_00668 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NBLEGCCO_00669 4.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NBLEGCCO_00670 2e-154 yitU 3.1.3.104 S hydrolase
NBLEGCCO_00671 9.1e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NBLEGCCO_00676 8.3e-89 IQ reductase
NBLEGCCO_00677 4.2e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NBLEGCCO_00678 3e-53 S ABC-type cobalt transport system, permease component
NBLEGCCO_00679 2.4e-43 thiW S Thiamine-precursor transporter protein (ThiW)
NBLEGCCO_00680 6.4e-55 rmeB K transcriptional regulator, MerR family
NBLEGCCO_00681 2.9e-111 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
NBLEGCCO_00683 9.5e-10 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NBLEGCCO_00684 6e-120 J 2'-5' RNA ligase superfamily
NBLEGCCO_00685 3.1e-130 XK27_07210 6.1.1.6 S B3 4 domain
NBLEGCCO_00686 1.1e-192 adhP 1.1.1.1 C alcohol dehydrogenase
NBLEGCCO_00687 4.7e-60 M repeat protein
NBLEGCCO_00688 9e-08
NBLEGCCO_00689 2.8e-205 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NBLEGCCO_00690 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NBLEGCCO_00691 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NBLEGCCO_00692 1.1e-186 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NBLEGCCO_00693 4.6e-154 recO L Involved in DNA repair and RecF pathway recombination
NBLEGCCO_00694 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NBLEGCCO_00695 2.3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NBLEGCCO_00696 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NBLEGCCO_00697 4.2e-178 phoH T phosphate starvation-inducible protein PhoH
NBLEGCCO_00698 2.1e-71 yqeY S YqeY-like protein
NBLEGCCO_00699 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NBLEGCCO_00700 3.1e-127 yfeJ 6.3.5.2 F glutamine amidotransferase
NBLEGCCO_00701 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NBLEGCCO_00702 8.7e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
NBLEGCCO_00703 2.3e-195 6.3.1.20 H Lipoate-protein ligase
NBLEGCCO_00704 7.4e-147 lytH 3.5.1.28 M Ami_3
NBLEGCCO_00705 2.2e-167 yniA G Phosphotransferase enzyme family
NBLEGCCO_00706 2.8e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NBLEGCCO_00707 1.6e-239 mmuP E amino acid
NBLEGCCO_00708 3.9e-114 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NBLEGCCO_00709 1.5e-206 hom1 1.1.1.3 E Homoserine dehydrogenase
NBLEGCCO_00710 1.7e-134 IQ KR domain
NBLEGCCO_00711 1e-151 cjaA ET ABC transporter substrate-binding protein
NBLEGCCO_00712 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NBLEGCCO_00713 1.7e-90 P ABC transporter permease
NBLEGCCO_00714 2.3e-111 papP P ABC transporter, permease protein
NBLEGCCO_00716 2.7e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NBLEGCCO_00717 1.3e-218 metC1 2.5.1.48, 4.4.1.8 E cystathionine
NBLEGCCO_00718 9.7e-83 slyA K Transcriptional regulator
NBLEGCCO_00719 7.1e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NBLEGCCO_00720 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBLEGCCO_00721 4.4e-58
NBLEGCCO_00722 2.8e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NBLEGCCO_00723 3.2e-178 prmA J Ribosomal protein L11 methyltransferase
NBLEGCCO_00724 8e-54
NBLEGCCO_00726 2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NBLEGCCO_00727 2.6e-94 S integral membrane protein
NBLEGCCO_00728 1.6e-76 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NBLEGCCO_00729 1.6e-185 argE 3.5.1.16 E Acetylornithine deacetylase
NBLEGCCO_00730 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NBLEGCCO_00732 6.8e-113 yfbR S HD containing hydrolase-like enzyme
NBLEGCCO_00733 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NBLEGCCO_00734 2.8e-137 cof S haloacid dehalogenase-like hydrolase
NBLEGCCO_00735 3.7e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NBLEGCCO_00736 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NBLEGCCO_00737 2e-61
NBLEGCCO_00738 4.3e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NBLEGCCO_00739 1.2e-60 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NBLEGCCO_00740 0.0 dnaK O Heat shock 70 kDa protein
NBLEGCCO_00741 7.8e-176 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NBLEGCCO_00742 1.5e-96 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NBLEGCCO_00743 1.2e-68 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NBLEGCCO_00744 9.8e-77
NBLEGCCO_00757 9.8e-77
NBLEGCCO_00771 2.3e-24 K Bacterial regulatory proteins, tetR family
NBLEGCCO_00773 1.5e-141 ET Bacterial periplasmic substrate-binding proteins
NBLEGCCO_00774 4.5e-110 XK27_05795 P ABC transporter permease
NBLEGCCO_00775 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NBLEGCCO_00776 1.2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBLEGCCO_00777 1.9e-158 sufD O Uncharacterized protein family (UPF0051)
NBLEGCCO_00778 4.6e-236 F Permease
NBLEGCCO_00779 2e-21 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NBLEGCCO_00780 9.8e-77
NBLEGCCO_00782 8.1e-271 cydA 1.10.3.14 C ubiquinol oxidase
NBLEGCCO_00783 9.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NBLEGCCO_00784 2.9e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NBLEGCCO_00785 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NBLEGCCO_00786 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NBLEGCCO_00787 2.8e-244 brnQ U Component of the transport system for branched-chain amino acids
NBLEGCCO_00788 1.3e-250 lacZ 3.2.1.23 G -beta-galactosidase
NBLEGCCO_00789 1.7e-139 lacS G Transporter
NBLEGCCO_00790 3.2e-56 lacS G Transporter
NBLEGCCO_00791 4.6e-87 lacR K Transcriptional regulator
NBLEGCCO_00792 4.4e-125 IQ reductase
NBLEGCCO_00793 4.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBLEGCCO_00794 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBLEGCCO_00795 2e-35 nrdH O Glutaredoxin
NBLEGCCO_00796 1.4e-73 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NBLEGCCO_00798 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NBLEGCCO_00799 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NBLEGCCO_00800 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NBLEGCCO_00801 2.4e-21 S Protein of unknown function (DUF2508)
NBLEGCCO_00802 6.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NBLEGCCO_00803 4e-53 yaaQ S Cyclic-di-AMP receptor
NBLEGCCO_00804 1.9e-192 holB 2.7.7.7 L DNA polymerase III
NBLEGCCO_00805 1.5e-55 yabA L Involved in initiation control of chromosome replication
NBLEGCCO_00806 1.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NBLEGCCO_00807 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
NBLEGCCO_00808 2.1e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NBLEGCCO_00809 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NBLEGCCO_00810 6.7e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NBLEGCCO_00811 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NBLEGCCO_00812 3e-148 KT YcbB domain
NBLEGCCO_00813 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NBLEGCCO_00814 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NBLEGCCO_00815 8.2e-240 arcA 3.5.3.6 E Arginine
NBLEGCCO_00816 8.3e-24 L Plasmid pRiA4b ORF-3-like protein
NBLEGCCO_00817 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NBLEGCCO_00818 2.2e-204
NBLEGCCO_00819 1.7e-159 rapZ S Displays ATPase and GTPase activities
NBLEGCCO_00820 3.2e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NBLEGCCO_00821 1.9e-167 whiA K May be required for sporulation
NBLEGCCO_00822 7.2e-118 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NBLEGCCO_00823 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NBLEGCCO_00827 1.4e-234 L Transposase
NBLEGCCO_00828 3.2e-13
NBLEGCCO_00829 1.1e-78 tspO T TspO/MBR family
NBLEGCCO_00830 3.4e-56 S Sel1-like repeats.
NBLEGCCO_00831 1.8e-62 yjbR S YjbR
NBLEGCCO_00832 2.7e-120 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NBLEGCCO_00833 5.6e-64 S Domain of unknown function (DUF3841)
NBLEGCCO_00834 4.5e-112 licT K CAT RNA binding domain
NBLEGCCO_00835 4.7e-269 bglP 2.7.1.211 G phosphotransferase system
NBLEGCCO_00836 1.4e-262 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NBLEGCCO_00837 3.9e-19 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NBLEGCCO_00838 1e-22 D mRNA cleavage
NBLEGCCO_00839 4.4e-171 S Phosphotransferase system, EIIC
NBLEGCCO_00841 5.1e-142 S Oxidoreductase family, NAD-binding Rossmann fold
NBLEGCCO_00843 2.1e-191 nhaC C Na H antiporter NhaC
NBLEGCCO_00845 1e-73 ddaH 3.5.3.18 E Amidinotransferase
NBLEGCCO_00846 1.6e-88 S Aminoacyl-tRNA editing domain
NBLEGCCO_00847 1.3e-306 mco Q Multicopper oxidase
NBLEGCCO_00848 4.5e-49 K 2 iron, 2 sulfur cluster binding
NBLEGCCO_00849 3.2e-85 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NBLEGCCO_00850 4.3e-113 Q Methyltransferase domain
NBLEGCCO_00852 3.3e-101 S CAAX protease self-immunity
NBLEGCCO_00853 2.9e-93 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NBLEGCCO_00854 5.4e-11 fsr EGP Major Facilitator Superfamily
NBLEGCCO_00855 1.4e-81 fsr EGP Major Facilitator Superfamily
NBLEGCCO_00856 5.2e-63 K helix_turn_helix, arabinose operon control protein
NBLEGCCO_00857 8.8e-101 K helix_turn_helix multiple antibiotic resistance protein
NBLEGCCO_00858 1.4e-181 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NBLEGCCO_00860 1.3e-265 pipD E Dipeptidase
NBLEGCCO_00861 2.9e-162 endA F DNA RNA non-specific endonuclease
NBLEGCCO_00862 1e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NBLEGCCO_00863 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBLEGCCO_00864 9.6e-89 S Alpha/beta hydrolase of unknown function (DUF915)
NBLEGCCO_00865 2.5e-37 S Alpha/beta hydrolase of unknown function (DUF915)
NBLEGCCO_00867 9.2e-228
NBLEGCCO_00868 2.2e-193 V Beta-lactamase
NBLEGCCO_00869 1.4e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NBLEGCCO_00870 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NBLEGCCO_00871 9.1e-147 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NBLEGCCO_00872 9.2e-130 gntR K UbiC transcription regulator-associated domain protein
NBLEGCCO_00873 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NBLEGCCO_00874 3.6e-129
NBLEGCCO_00875 1.9e-264 pipD E Dipeptidase
NBLEGCCO_00876 4.1e-155 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NBLEGCCO_00877 2.4e-84 M1-874 K Domain of unknown function (DUF1836)
NBLEGCCO_00878 3e-90 GM epimerase
NBLEGCCO_00879 2.9e-249 yhdP S Transporter associated domain
NBLEGCCO_00880 2.4e-83 nrdI F Belongs to the NrdI family
NBLEGCCO_00881 6.5e-75 S 3-demethylubiquinone-9 3-methyltransferase
NBLEGCCO_00882 3.3e-206 yeaN P Transporter, major facilitator family protein
NBLEGCCO_00883 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NBLEGCCO_00884 8.6e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NBLEGCCO_00885 5.1e-81 uspA T universal stress protein
NBLEGCCO_00886 1.1e-77 K AsnC family
NBLEGCCO_00887 4.8e-158 C C4-dicarboxylate transmembrane transporter activity
NBLEGCCO_00888 2.7e-60 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
NBLEGCCO_00889 9.3e-141 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NBLEGCCO_00890 3.1e-101 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBLEGCCO_00891 4.7e-177 K helix_turn _helix lactose operon repressor
NBLEGCCO_00892 1.2e-308 pepF E oligoendopeptidase F
NBLEGCCO_00893 3.2e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NBLEGCCO_00894 3.1e-124 S Membrane
NBLEGCCO_00895 7.7e-42 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NBLEGCCO_00896 2e-62 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NBLEGCCO_00897 2.1e-277 lacS G Transporter
NBLEGCCO_00898 0.0 rafA 3.2.1.22 G alpha-galactosidase
NBLEGCCO_00899 4.6e-180 galR K Transcriptional regulator
NBLEGCCO_00900 1.9e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NBLEGCCO_00901 3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NBLEGCCO_00902 2.4e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NBLEGCCO_00903 3.9e-142 ptp3 3.1.3.48 T Tyrosine phosphatase family
NBLEGCCO_00904 1.8e-95 yxkA S Phosphatidylethanolamine-binding protein
NBLEGCCO_00905 1.5e-35
NBLEGCCO_00906 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NBLEGCCO_00907 6.3e-120 tcyB U Binding-protein-dependent transport system inner membrane component
NBLEGCCO_00908 2.8e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NBLEGCCO_00909 2e-52
NBLEGCCO_00910 7.6e-169 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBLEGCCO_00911 7.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NBLEGCCO_00912 5e-145 pnuC H nicotinamide mononucleotide transporter
NBLEGCCO_00913 5e-90 ymdB S Macro domain protein
NBLEGCCO_00914 0.0 pepO 3.4.24.71 O Peptidase family M13
NBLEGCCO_00915 1.8e-229 pbuG S permease
NBLEGCCO_00916 1e-44
NBLEGCCO_00917 4.3e-209 S Putative metallopeptidase domain
NBLEGCCO_00918 4.5e-200 3.1.3.1 S associated with various cellular activities
NBLEGCCO_00919 6.5e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NBLEGCCO_00920 2.6e-64 yeaO S Protein of unknown function, DUF488
NBLEGCCO_00922 1.4e-124 yrkL S Flavodoxin-like fold
NBLEGCCO_00923 1.3e-54
NBLEGCCO_00924 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NBLEGCCO_00925 2.3e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NBLEGCCO_00926 1.7e-100
NBLEGCCO_00927 9.5e-26
NBLEGCCO_00928 1.6e-166 scrR K Transcriptional regulator, LacI family
NBLEGCCO_00929 1e-15
NBLEGCCO_00930 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NBLEGCCO_00931 7.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NBLEGCCO_00932 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NBLEGCCO_00933 2.3e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NBLEGCCO_00934 1.5e-253 yifK E Amino acid permease
NBLEGCCO_00935 3.2e-289 clcA P chloride
NBLEGCCO_00936 4.5e-33 secG U Preprotein translocase
NBLEGCCO_00937 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NBLEGCCO_00938 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NBLEGCCO_00939 5.5e-109 yxjI
NBLEGCCO_00940 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NBLEGCCO_00941 3.5e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NBLEGCCO_00942 1.1e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NBLEGCCO_00943 2.1e-88 K Acetyltransferase (GNAT) domain
NBLEGCCO_00944 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
NBLEGCCO_00945 5.7e-166 murB 1.3.1.98 M Cell wall formation
NBLEGCCO_00946 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NBLEGCCO_00947 9.1e-116 ybbR S YbbR-like protein
NBLEGCCO_00948 5.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NBLEGCCO_00949 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NBLEGCCO_00950 3.3e-52
NBLEGCCO_00951 4.2e-211 oatA I Acyltransferase
NBLEGCCO_00952 1.5e-149 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
NBLEGCCO_00953 2.4e-75 lytE M Lysin motif
NBLEGCCO_00954 9.2e-160 MA20_14895 S Conserved hypothetical protein 698
NBLEGCCO_00955 3.3e-183 fruR3 K Transcriptional regulator, LacI family
NBLEGCCO_00956 4.8e-157 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NBLEGCCO_00957 1.5e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBLEGCCO_00958 1e-56 trxA1 O Belongs to the thioredoxin family
NBLEGCCO_00959 2.3e-142 terC P membrane
NBLEGCCO_00960 2.2e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NBLEGCCO_00961 1.8e-170 corA P CorA-like Mg2+ transporter protein
NBLEGCCO_00962 9.3e-229 pbuX F xanthine permease
NBLEGCCO_00963 0.0 FbpA K Fibronectin-binding protein
NBLEGCCO_00964 7.1e-161 degV S EDD domain protein, DegV family
NBLEGCCO_00965 2.3e-97
NBLEGCCO_00966 1.2e-132 S Belongs to the UPF0246 family
NBLEGCCO_00967 2.5e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NBLEGCCO_00968 5.3e-113 ylbE GM NAD(P)H-binding
NBLEGCCO_00969 3.5e-99 K Acetyltransferase (GNAT) domain
NBLEGCCO_00970 2.9e-122 L Integrase core domain
NBLEGCCO_00971 1.9e-46 L Transposase
NBLEGCCO_00972 8.1e-47 S Acetyltransferase (GNAT) domain
NBLEGCCO_00973 4.1e-21 L Transposase
NBLEGCCO_00974 4.1e-21 L Transposase
NBLEGCCO_00975 4.2e-17 lmrB EGP Major facilitator Superfamily
NBLEGCCO_00977 9.3e-245 yhjX P Major Facilitator Superfamily
NBLEGCCO_00978 1.7e-117 S Protein of unknown function (DUF554)
NBLEGCCO_00979 1.4e-256 rarA L recombination factor protein RarA
NBLEGCCO_00981 0.0 oppD EP Psort location Cytoplasmic, score
NBLEGCCO_00982 8e-243 codA 3.5.4.1 F cytosine deaminase
NBLEGCCO_00983 9.4e-245 U Belongs to the purine-cytosine permease (2.A.39) family
NBLEGCCO_00984 5.9e-82 yebR 1.8.4.14 T GAF domain-containing protein
NBLEGCCO_00985 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NBLEGCCO_00986 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NBLEGCCO_00987 2.3e-71 yqkB S Belongs to the HesB IscA family
NBLEGCCO_00988 3.6e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
NBLEGCCO_00989 5.2e-95 S Protein of unknown function (DUF1440)
NBLEGCCO_00990 3e-240 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NBLEGCCO_00991 4.1e-21 L Transposase
NBLEGCCO_00992 3.1e-36 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NBLEGCCO_00993 4.6e-56 ydiI Q Thioesterase superfamily
NBLEGCCO_00994 2.6e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NBLEGCCO_00995 3.4e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NBLEGCCO_00996 7.3e-217 G Transporter, major facilitator family protein
NBLEGCCO_00997 4.1e-21 L Transposase
NBLEGCCO_00998 1.2e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NBLEGCCO_00999 4.3e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
NBLEGCCO_01000 1.4e-52 cps3I G Acyltransferase family
NBLEGCCO_01001 4.5e-45 M biosynthesis protein
NBLEGCCO_01002 1.2e-94 cps3F
NBLEGCCO_01003 4.6e-148 cps1D M Domain of unknown function (DUF4422)
NBLEGCCO_01004 1.1e-118 rfbP M Bacterial sugar transferase
NBLEGCCO_01005 4.2e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
NBLEGCCO_01006 1.3e-07
NBLEGCCO_01007 3.8e-31 S Protein of unknown function (DUF2922)
NBLEGCCO_01008 2.7e-139 yihY S Belongs to the UPF0761 family
NBLEGCCO_01009 0.0 XK27_08315 M Sulfatase
NBLEGCCO_01010 1.6e-224 aadAT EK Aminotransferase, class I
NBLEGCCO_01011 6.1e-150 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NBLEGCCO_01012 1.8e-142 ET Bacterial periplasmic substrate-binding proteins
NBLEGCCO_01013 1.4e-107 ybbL S ABC transporter, ATP-binding protein
NBLEGCCO_01014 2.5e-133 ybbM S Uncharacterised protein family (UPF0014)
NBLEGCCO_01015 7.1e-36 rmeB K transcriptional regulator, MerR family
NBLEGCCO_01016 3.4e-39 rmeB K transcriptional regulator, MerR family
NBLEGCCO_01017 3.4e-47 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
NBLEGCCO_01018 1.3e-112 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NBLEGCCO_01019 1.6e-57 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
NBLEGCCO_01021 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NBLEGCCO_01022 2e-260 guaD 3.5.4.3 F Amidohydrolase family
NBLEGCCO_01023 1.9e-37 tdh 1.1.1.14 C Zinc-binding dehydrogenase
NBLEGCCO_01024 2.5e-104 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NBLEGCCO_01025 1.1e-30 S Sugar efflux transporter for intercellular exchange
NBLEGCCO_01026 3.2e-30 S RelE-like toxin of type II toxin-antitoxin system HigB
NBLEGCCO_01027 2e-136 E Amino acid permease
NBLEGCCO_01028 4.7e-10 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NBLEGCCO_01029 5e-216 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NBLEGCCO_01030 2.2e-16
NBLEGCCO_01031 6.6e-65 S aminoacyl-tRNA ligase activity
NBLEGCCO_01032 5.6e-118
NBLEGCCO_01033 9.5e-49 S Phage gp6-like head-tail connector protein
NBLEGCCO_01034 2.5e-15
NBLEGCCO_01035 1.4e-51 S exonuclease activity
NBLEGCCO_01036 1.4e-52
NBLEGCCO_01037 3.8e-89 S Phage major tail protein 2
NBLEGCCO_01038 7.6e-47 S Pfam:Phage_TAC_12
NBLEGCCO_01039 6.6e-169 S peptidoglycan catabolic process
NBLEGCCO_01040 2.1e-108 S Phage tail protein
NBLEGCCO_01041 0.0 S peptidoglycan catabolic process
NBLEGCCO_01044 4.1e-23 S Bacteriophage holin family
NBLEGCCO_01045 9.1e-09
NBLEGCCO_01046 7.6e-30 S peptidoglycan catabolic process
NBLEGCCO_01047 8.1e-40 M hydrolase, family 25
NBLEGCCO_01048 2.2e-100 L Belongs to the 'phage' integrase family
NBLEGCCO_01049 2.3e-162 czcD P cation diffusion facilitator family transporter
NBLEGCCO_01050 3.5e-188 L PFAM Integrase, catalytic core
NBLEGCCO_01052 1e-78 copY K Copper transport repressor CopY TcrY
NBLEGCCO_01054 1.6e-76 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NBLEGCCO_01055 9.6e-172 mutR K Transcriptional activator, Rgg GadR MutR family
NBLEGCCO_01056 5.3e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NBLEGCCO_01057 3.2e-229 gntT EG Gluconate
NBLEGCCO_01058 1.4e-181 K Transcriptional regulator, LacI family
NBLEGCCO_01059 2.5e-61 yneR
NBLEGCCO_01060 2.8e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NBLEGCCO_01061 2.2e-96 V VanZ like family
NBLEGCCO_01062 6.2e-290 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NBLEGCCO_01064 3.1e-39 ywnB S NAD(P)H-binding
NBLEGCCO_01065 2.1e-65 yjcE P Sodium proton antiporter
NBLEGCCO_01066 1.7e-75
NBLEGCCO_01067 1.3e-184
NBLEGCCO_01068 2.1e-128 narI 1.7.5.1 C Nitrate reductase
NBLEGCCO_01069 3.1e-102 narJ C Nitrate reductase delta subunit
NBLEGCCO_01070 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
NBLEGCCO_01071 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NBLEGCCO_01072 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NBLEGCCO_01073 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NBLEGCCO_01074 1.5e-230 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NBLEGCCO_01075 9.3e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NBLEGCCO_01076 1.1e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NBLEGCCO_01077 4.2e-40
NBLEGCCO_01078 1.4e-77 nreA T GAF domain
NBLEGCCO_01079 3.9e-182 comP 2.7.13.3 F Sensor histidine kinase
NBLEGCCO_01080 2e-115 nreC K PFAM regulatory protein LuxR
NBLEGCCO_01081 1.2e-39
NBLEGCCO_01082 1.5e-183
NBLEGCCO_01083 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
NBLEGCCO_01085 4.6e-134 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NBLEGCCO_01086 4.5e-163 hipB K Helix-turn-helix
NBLEGCCO_01087 1.5e-58 yitW S Iron-sulfur cluster assembly protein
NBLEGCCO_01088 1.4e-215 narK P Major Facilitator Superfamily
NBLEGCCO_01089 3.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NBLEGCCO_01090 6.4e-35 moaD 2.8.1.12 H ThiS family
NBLEGCCO_01091 2.2e-72 moaE 2.8.1.12 H MoaE protein
NBLEGCCO_01092 3.4e-58 S Flavodoxin
NBLEGCCO_01093 3.3e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBLEGCCO_01094 7.7e-143 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
NBLEGCCO_01095 2.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
NBLEGCCO_01096 8e-54 yitW S Iron-sulfur cluster assembly protein
NBLEGCCO_01097 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
NBLEGCCO_01098 1.6e-257 XK27_04775 S PAS domain
NBLEGCCO_01099 3.2e-142 EG EamA-like transporter family
NBLEGCCO_01100 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
NBLEGCCO_01101 4.1e-21 L Transposase
NBLEGCCO_01102 0.0 smc D Required for chromosome condensation and partitioning
NBLEGCCO_01103 5.1e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NBLEGCCO_01104 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NBLEGCCO_01105 1.1e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NBLEGCCO_01106 1.2e-32 cspB K Cold shock protein
NBLEGCCO_01107 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NBLEGCCO_01109 1.2e-99 divIVA D DivIVA domain protein
NBLEGCCO_01110 3.8e-145 ylmH S S4 domain protein
NBLEGCCO_01111 1.2e-40 yggT S YGGT family
NBLEGCCO_01112 2.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NBLEGCCO_01113 2.3e-216 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NBLEGCCO_01114 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NBLEGCCO_01115 1.9e-147 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NBLEGCCO_01116 5.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NBLEGCCO_01117 6.8e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NBLEGCCO_01118 5.4e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NBLEGCCO_01119 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NBLEGCCO_01120 7e-09 ftsL D Cell division protein FtsL
NBLEGCCO_01121 1.5e-169 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NBLEGCCO_01122 5.6e-79 mraZ K Belongs to the MraZ family
NBLEGCCO_01123 8.6e-287 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NBLEGCCO_01124 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NBLEGCCO_01125 6.2e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NBLEGCCO_01126 1.4e-142 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NBLEGCCO_01127 8.7e-108 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NBLEGCCO_01128 4.9e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NBLEGCCO_01129 2.5e-69 psiE S Phosphate-starvation-inducible E
NBLEGCCO_01130 2.8e-36 V CAAX protease self-immunity
NBLEGCCO_01132 6.4e-93 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBLEGCCO_01133 1.2e-140 P Belongs to the nlpA lipoprotein family
NBLEGCCO_01134 4.3e-242 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NBLEGCCO_01135 2.3e-241 yfnA E amino acid
NBLEGCCO_01136 3.2e-83 S NADPH-dependent FMN reductase
NBLEGCCO_01138 1.3e-156 L Thioesterase-like superfamily
NBLEGCCO_01139 1.1e-50 lacA S transferase hexapeptide repeat
NBLEGCCO_01140 7.5e-83 L Helix-turn-helix domain
NBLEGCCO_01142 7.7e-91 K Bacterial regulatory helix-turn-helix protein, lysR family
NBLEGCCO_01143 8e-56 C Flavodoxin
NBLEGCCO_01144 1.9e-35 S Cyclophilin-like
NBLEGCCO_01145 2.8e-30 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NBLEGCCO_01146 3.3e-83 C Aldo keto reductase
NBLEGCCO_01149 6.4e-19 S Uncharacterized protein conserved in bacteria (DUF2255)
NBLEGCCO_01150 7.7e-97 C aldo keto reductase
NBLEGCCO_01151 1.5e-90 P Cadmium resistance transporter
NBLEGCCO_01152 2.1e-56 ydzE EG EamA-like transporter family
NBLEGCCO_01153 1.7e-54 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NBLEGCCO_01155 2.6e-90 isdH M Iron Transport-associated domain
NBLEGCCO_01156 2.3e-94 M Iron Transport-associated domain
NBLEGCCO_01157 1.2e-147 isdE P Periplasmic binding protein
NBLEGCCO_01158 1.2e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBLEGCCO_01159 2.8e-85 ykhA 3.1.2.20 I Thioesterase superfamily
NBLEGCCO_01160 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
NBLEGCCO_01161 1.1e-116 K Transcriptional regulator, TetR family
NBLEGCCO_01162 9.8e-10 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NBLEGCCO_01163 5.3e-209 S Type IV secretion-system coupling protein DNA-binding domain
NBLEGCCO_01164 8.9e-83 F Hydrolase, NUDIX family
NBLEGCCO_01165 1.4e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NBLEGCCO_01166 1.1e-192 ytjP 3.5.1.18 E Dipeptidase
NBLEGCCO_01167 1.5e-203 arcD S C4-dicarboxylate anaerobic carrier
NBLEGCCO_01168 2.1e-258 nylA 3.5.1.4 J Belongs to the amidase family
NBLEGCCO_01169 1.8e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NBLEGCCO_01171 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBLEGCCO_01172 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBLEGCCO_01173 4.2e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NBLEGCCO_01174 2e-246 S response to antibiotic
NBLEGCCO_01175 3.3e-255 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NBLEGCCO_01176 7.7e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NBLEGCCO_01177 1.5e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NBLEGCCO_01178 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NBLEGCCO_01179 6.9e-163 K AI-2E family transporter
NBLEGCCO_01180 2.1e-11 K transcriptional regulator
NBLEGCCO_01181 2.5e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NBLEGCCO_01182 2.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBLEGCCO_01183 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NBLEGCCO_01184 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NBLEGCCO_01185 1.3e-162 yvgN C Aldo keto reductase
NBLEGCCO_01186 6.5e-285 glpQ 3.1.4.46 C phosphodiesterase
NBLEGCCO_01187 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBLEGCCO_01188 7.4e-106 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NBLEGCCO_01189 5e-187 I Alpha beta
NBLEGCCO_01190 6.7e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
NBLEGCCO_01191 3.2e-253 yjjP S Putative threonine/serine exporter
NBLEGCCO_01192 3.8e-162 mleR K LysR family transcriptional regulator
NBLEGCCO_01193 5.6e-224 yflS P Sodium:sulfate symporter transmembrane region
NBLEGCCO_01194 6.1e-215 frdC 1.3.5.4 C FAD binding domain
NBLEGCCO_01195 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NBLEGCCO_01196 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
NBLEGCCO_01197 2e-183 XK27_09615 S reductase
NBLEGCCO_01198 9.4e-231 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NBLEGCCO_01199 2.4e-79 mleR K LysR family
NBLEGCCO_01200 2.7e-20 nlhH_1 I Carboxylesterase family
NBLEGCCO_01201 1e-08 nlhH_1 I acetylesterase activity
NBLEGCCO_01202 1.8e-107 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NBLEGCCO_01203 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
NBLEGCCO_01204 4e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NBLEGCCO_01205 5.9e-293 scrB 3.2.1.26 GH32 G invertase
NBLEGCCO_01206 8e-260 S Uncharacterized protein conserved in bacteria (DUF2252)
NBLEGCCO_01207 7.1e-164 K LysR substrate binding domain
NBLEGCCO_01208 6.8e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NBLEGCCO_01209 3.9e-110
NBLEGCCO_01211 6.2e-244 yjeM E Amino Acid
NBLEGCCO_01212 9.1e-125 S membrane transporter protein
NBLEGCCO_01213 8.6e-180 S AI-2E family transporter
NBLEGCCO_01214 8.8e-215 phbA 2.3.1.9 I Belongs to the thiolase family
NBLEGCCO_01215 1.2e-160 rssA S Phospholipase, patatin family
NBLEGCCO_01216 4.4e-169 K LysR substrate binding domain
NBLEGCCO_01217 0.0 1.3.5.4 C FAD binding domain
NBLEGCCO_01218 1.3e-70 S Domain of unknown function (DUF4352)
NBLEGCCO_01219 2e-113 yicL EG EamA-like transporter family
NBLEGCCO_01220 1.1e-62
NBLEGCCO_01223 9e-14
NBLEGCCO_01224 6e-61 S pyridoxamine 5-phosphate
NBLEGCCO_01225 2.8e-179 yobV1 K WYL domain
NBLEGCCO_01226 2.7e-244 XK27_08635 S UPF0210 protein
NBLEGCCO_01227 2.5e-40 gcvR T Belongs to the UPF0237 family
NBLEGCCO_01228 8.2e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NBLEGCCO_01229 3.4e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NBLEGCCO_01230 1e-104
NBLEGCCO_01231 2.4e-83 dps P Belongs to the Dps family
NBLEGCCO_01232 1e-301 ybiT S ABC transporter, ATP-binding protein
NBLEGCCO_01234 8.7e-33 yneR S Belongs to the HesB IscA family
NBLEGCCO_01235 3.2e-136 S NADPH-dependent FMN reductase
NBLEGCCO_01236 6.9e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NBLEGCCO_01237 1.3e-157 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NBLEGCCO_01238 2e-103 yvdD 3.2.2.10 S Belongs to the LOG family
NBLEGCCO_01239 4.9e-63 S Domain of unknown function (DUF4828)
NBLEGCCO_01240 4.9e-190 mocA S Oxidoreductase
NBLEGCCO_01241 1.5e-226 yfmL 3.6.4.13 L DEAD DEAH box helicase
NBLEGCCO_01243 3e-75 gtcA S Teichoic acid glycosylation protein
NBLEGCCO_01244 8.5e-78 fld C Flavodoxin
NBLEGCCO_01245 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
NBLEGCCO_01246 1.6e-255 S Putative peptidoglycan binding domain
NBLEGCCO_01247 3.3e-86 uspA T Belongs to the universal stress protein A family
NBLEGCCO_01248 6e-271 pepV 3.5.1.18 E dipeptidase PepV
NBLEGCCO_01249 2.4e-37 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NBLEGCCO_01250 7.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NBLEGCCO_01251 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NBLEGCCO_01252 8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NBLEGCCO_01253 2.1e-238 purD 6.3.4.13 F Belongs to the GARS family
NBLEGCCO_01254 9.1e-110 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NBLEGCCO_01255 4.6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NBLEGCCO_01256 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NBLEGCCO_01257 5.4e-256 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NBLEGCCO_01258 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NBLEGCCO_01259 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NBLEGCCO_01260 1.3e-91 K transcriptional regulator
NBLEGCCO_01261 2.4e-125 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
NBLEGCCO_01262 1e-180 ybhR V ABC transporter
NBLEGCCO_01263 2.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
NBLEGCCO_01264 3.7e-154 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NBLEGCCO_01265 1.4e-234 kgtP EGP Sugar (and other) transporter
NBLEGCCO_01266 4.9e-07 S YSIRK type signal peptide
NBLEGCCO_01268 3.7e-29
NBLEGCCO_01269 1.9e-158 xth 3.1.11.2 L exodeoxyribonuclease III
NBLEGCCO_01270 6.5e-134 cinA 3.5.1.42 S Belongs to the CinA family
NBLEGCCO_01271 7.7e-150 ponA V Beta-lactamase enzyme family
NBLEGCCO_01272 7.1e-223 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NBLEGCCO_01273 2.2e-96
NBLEGCCO_01274 1.2e-196 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NBLEGCCO_01275 2.6e-106 lssY 3.6.1.27 I Acid phosphatase homologues
NBLEGCCO_01276 4.6e-54 S MazG-like family
NBLEGCCO_01277 0.0 L Helicase C-terminal domain protein
NBLEGCCO_01278 3.6e-70 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NBLEGCCO_01279 2.1e-94 K transcriptional regulator
NBLEGCCO_01280 2.7e-250 lmrB EGP Major facilitator Superfamily
NBLEGCCO_01281 6.6e-14 S Domain of unknown function (DUF4811)
NBLEGCCO_01283 1.9e-28 S Cytochrome B5
NBLEGCCO_01284 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NBLEGCCO_01285 2.3e-212 2.1.1.14 E methionine synthase, vitamin-B12 independent
NBLEGCCO_01286 3.6e-28 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NBLEGCCO_01287 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
NBLEGCCO_01288 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
NBLEGCCO_01289 3.3e-66 wecD K Acetyltransferase (GNAT) family
NBLEGCCO_01290 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NBLEGCCO_01291 1.5e-109 cycA E Amino acid permease
NBLEGCCO_01292 2.1e-90 cycA E Amino acid permease
NBLEGCCO_01293 6.5e-134 D nuclear chromosome segregation
NBLEGCCO_01294 4.5e-256 dtpT U amino acid peptide transporter
NBLEGCCO_01295 3.3e-163 yjjH S Calcineurin-like phosphoesterase
NBLEGCCO_01296 1.9e-09
NBLEGCCO_01297 2.4e-110 3.1.3.73 G phosphoglycerate mutase
NBLEGCCO_01298 1.5e-109 C aldo keto reductase
NBLEGCCO_01299 3.3e-200 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NBLEGCCO_01300 1.7e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NBLEGCCO_01301 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NBLEGCCO_01302 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
NBLEGCCO_01303 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NBLEGCCO_01304 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NBLEGCCO_01305 9e-104 sigH K Belongs to the sigma-70 factor family
NBLEGCCO_01306 1.2e-76 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBLEGCCO_01307 2.9e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NBLEGCCO_01308 7.6e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NBLEGCCO_01309 2.4e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NBLEGCCO_01310 6.2e-76 argR K Regulates arginine biosynthesis genes
NBLEGCCO_01311 2.1e-302 recN L May be involved in recombinational repair of damaged DNA
NBLEGCCO_01312 3.3e-15
NBLEGCCO_01313 6.7e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NBLEGCCO_01314 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NBLEGCCO_01315 1.7e-153 S Sucrose-6F-phosphate phosphohydrolase
NBLEGCCO_01316 2.5e-158 1.6.5.2 GM NAD(P)H-binding
NBLEGCCO_01317 1.4e-156 S Alpha beta hydrolase
NBLEGCCO_01318 1.9e-235 lmrB EGP Major facilitator Superfamily
NBLEGCCO_01320 0.0 S Bacterial membrane protein YfhO
NBLEGCCO_01321 1.6e-49
NBLEGCCO_01322 0.0 kup P Transport of potassium into the cell
NBLEGCCO_01324 1.1e-283 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NBLEGCCO_01325 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NBLEGCCO_01326 0.0 yjbQ P TrkA C-terminal domain protein
NBLEGCCO_01327 1.4e-275 pipD E Dipeptidase
NBLEGCCO_01328 8.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
NBLEGCCO_01329 2.6e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NBLEGCCO_01330 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBLEGCCO_01331 4.5e-168 T Calcineurin-like phosphoesterase superfamily domain
NBLEGCCO_01332 3.1e-158 EGP Major facilitator Superfamily
NBLEGCCO_01333 1.1e-199 mdtG EGP Major facilitator Superfamily
NBLEGCCO_01334 9.9e-250 yhdP S Transporter associated domain
NBLEGCCO_01335 2.5e-212 naiP EGP Major facilitator Superfamily
NBLEGCCO_01336 7.6e-70 K LysR substrate binding domain protein
NBLEGCCO_01337 7.5e-16 K LysR substrate binding domain protein
NBLEGCCO_01338 1.2e-216 E GDSL-like Lipase/Acylhydrolase family
NBLEGCCO_01339 2.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
NBLEGCCO_01340 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
NBLEGCCO_01341 1.5e-204 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NBLEGCCO_01342 5.8e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NBLEGCCO_01343 6.3e-183 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NBLEGCCO_01344 3.6e-54 yphJ 4.1.1.44 S decarboxylase
NBLEGCCO_01345 4e-114 S membrane
NBLEGCCO_01346 1.1e-108 S VIT family
NBLEGCCO_01347 2.5e-83 usp1 T Belongs to the universal stress protein A family
NBLEGCCO_01348 1e-30 elaA S GNAT family
NBLEGCCO_01349 3.9e-210 S CAAX protease self-immunity
NBLEGCCO_01350 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NBLEGCCO_01351 1.5e-58
NBLEGCCO_01352 4.3e-74 merR K MerR HTH family regulatory protein
NBLEGCCO_01353 2.8e-266 lmrB EGP Major facilitator Superfamily
NBLEGCCO_01354 5.4e-111 S Domain of unknown function (DUF4811)
NBLEGCCO_01355 8.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NBLEGCCO_01356 1.3e-246 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NBLEGCCO_01357 6.4e-204 araR K Transcriptional regulator
NBLEGCCO_01358 3.5e-137 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NBLEGCCO_01359 9.8e-310 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
NBLEGCCO_01360 5.1e-167 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NBLEGCCO_01361 2.7e-20 L transposase, IS605 OrfB family
NBLEGCCO_01362 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NBLEGCCO_01363 3.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NBLEGCCO_01364 2.3e-99 ywlG S Belongs to the UPF0340 family
NBLEGCCO_01365 2.8e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBLEGCCO_01366 2e-203 yacL S domain protein
NBLEGCCO_01367 8e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NBLEGCCO_01368 1.9e-95 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NBLEGCCO_01369 3.5e-54 HA62_12640 S GCN5-related N-acetyl-transferase
NBLEGCCO_01370 8.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NBLEGCCO_01371 1.2e-93 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
NBLEGCCO_01372 9.8e-263 pepC 3.4.22.40 E Peptidase C1-like family
NBLEGCCO_01373 2.1e-165 I alpha/beta hydrolase fold
NBLEGCCO_01374 1.5e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBLEGCCO_01375 2.1e-166 mleP2 S Sodium Bile acid symporter family
NBLEGCCO_01376 1.5e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NBLEGCCO_01377 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NBLEGCCO_01378 2.5e-73 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NBLEGCCO_01380 2.6e-66
NBLEGCCO_01381 3.7e-128 K Transcriptional regulatory protein, C-terminal domain protein
NBLEGCCO_01382 5.1e-159 pstS P Phosphate
NBLEGCCO_01383 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
NBLEGCCO_01384 3.3e-150 pstA P Phosphate transport system permease protein PstA
NBLEGCCO_01385 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NBLEGCCO_01386 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
NBLEGCCO_01387 8.5e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NBLEGCCO_01388 1e-38 ylqC S Belongs to the UPF0109 family
NBLEGCCO_01389 8e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NBLEGCCO_01390 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NBLEGCCO_01391 1.1e-259 yfnA E Amino Acid
NBLEGCCO_01392 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NBLEGCCO_01393 1.3e-298 cas3 L CRISPR-associated helicase cas3
NBLEGCCO_01394 1.6e-145 casA L the current gene model (or a revised gene model) may contain a frame shift
NBLEGCCO_01395 3.2e-40 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
NBLEGCCO_01396 1.5e-128 casC L CT1975-like protein
NBLEGCCO_01397 1.2e-65 casD S CRISPR-associated protein (Cas_Cas5)
NBLEGCCO_01398 6.7e-71 casE S CRISPR_assoc
NBLEGCCO_01399 1e-117 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NBLEGCCO_01400 7.9e-216 L transposase, IS605 OrfB family
NBLEGCCO_01401 2.2e-77 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
NBLEGCCO_01402 2.3e-72 K helix_turn_helix, mercury resistance
NBLEGCCO_01403 1.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
NBLEGCCO_01404 7.6e-191 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NBLEGCCO_01405 1.8e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NBLEGCCO_01406 1.7e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NBLEGCCO_01407 1.7e-134 ycsF S LamB/YcsF family
NBLEGCCO_01408 2.7e-211 ycsG P Natural resistance-associated macrophage protein
NBLEGCCO_01409 3e-207 EGP Major facilitator Superfamily
NBLEGCCO_01410 7.5e-255 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NBLEGCCO_01411 1.1e-52 trxA O Belongs to the thioredoxin family
NBLEGCCO_01412 2.2e-152 mleP3 S Membrane transport protein
NBLEGCCO_01414 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NBLEGCCO_01415 5.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NBLEGCCO_01416 5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NBLEGCCO_01417 1.7e-173 2.4.2.29 F queuine tRNA-ribosyltransferase activity
NBLEGCCO_01418 9.3e-42 yajC U Preprotein translocase
NBLEGCCO_01419 2e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NBLEGCCO_01420 5.1e-230 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NBLEGCCO_01421 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NBLEGCCO_01422 1.2e-42 yrzL S Belongs to the UPF0297 family
NBLEGCCO_01423 1.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NBLEGCCO_01424 1.8e-34 yrzB S Belongs to the UPF0473 family
NBLEGCCO_01425 4.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBLEGCCO_01426 1.4e-90 cvpA S Colicin V production protein
NBLEGCCO_01427 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NBLEGCCO_01428 3.9e-53 trxA O Belongs to the thioredoxin family
NBLEGCCO_01429 5.5e-223 clcA_2 P Chloride transporter, ClC family
NBLEGCCO_01430 4.8e-91 yslB S Protein of unknown function (DUF2507)
NBLEGCCO_01431 1.2e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NBLEGCCO_01432 3.1e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NBLEGCCO_01433 2e-94 S Phosphoesterase
NBLEGCCO_01434 1.3e-61 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NBLEGCCO_01436 8.7e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NBLEGCCO_01437 7.6e-58 XK27_04120 S Putative amino acid metabolism
NBLEGCCO_01438 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NBLEGCCO_01439 1.1e-80 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBLEGCCO_01440 1.2e-146 yitS S EDD domain protein, DegV family
NBLEGCCO_01441 6.5e-90 racA K Domain of unknown function (DUF1836)
NBLEGCCO_01442 8.7e-181 yfeX P Peroxidase
NBLEGCCO_01443 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NBLEGCCO_01444 4.6e-122 manY G PTS system
NBLEGCCO_01445 3e-170 manN G system, mannose fructose sorbose family IID component
NBLEGCCO_01446 1.2e-57 S Domain of unknown function (DUF956)
NBLEGCCO_01447 1.1e-130 sptS 2.7.13.3 T Histidine kinase
NBLEGCCO_01448 1.4e-79 K response regulator
NBLEGCCO_01449 1.6e-111 2.7.6.5 T Region found in RelA / SpoT proteins
NBLEGCCO_01450 1.4e-268 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NBLEGCCO_01451 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBLEGCCO_01452 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NBLEGCCO_01453 1.7e-18
NBLEGCCO_01454 2.9e-199 L Psort location Cytoplasmic, score
NBLEGCCO_01455 1.1e-69 pnuC H Nicotinamide mononucleotide transporter
NBLEGCCO_01456 9.2e-245 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NBLEGCCO_01457 1.3e-81 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
NBLEGCCO_01458 1.1e-139 D CobQ CobB MinD ParA nucleotide binding domain protein
NBLEGCCO_01460 7.7e-29
NBLEGCCO_01461 5.7e-134 repA S Replication initiator protein A
NBLEGCCO_01462 1.6e-38
NBLEGCCO_01463 3.3e-40 S Bacterial epsilon antitoxin
NBLEGCCO_01464 2e-145 2.7.1.176 S Zeta toxin
NBLEGCCO_01465 1.2e-37
NBLEGCCO_01466 2.5e-27
NBLEGCCO_01467 7.9e-308 traA L MobA MobL family protein
NBLEGCCO_01468 1.1e-50
NBLEGCCO_01469 7.2e-99
NBLEGCCO_01470 1e-51 S Cag pathogenicity island, type IV secretory system
NBLEGCCO_01471 1.7e-36
NBLEGCCO_01472 8.4e-114
NBLEGCCO_01473 0.0 traE U AAA-like domain
NBLEGCCO_01474 5.6e-216 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
NBLEGCCO_01475 1.5e-190 M CHAP domain
NBLEGCCO_01476 1.8e-86
NBLEGCCO_01477 8.7e-81
NBLEGCCO_01478 5.5e-262 traK U TraM recognition site of TraD and TraG
NBLEGCCO_01479 5.2e-63
NBLEGCCO_01480 1.3e-151
NBLEGCCO_01481 2.1e-67
NBLEGCCO_01482 3.8e-22 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NBLEGCCO_01483 4.5e-228 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NBLEGCCO_01484 3e-200 sbcC L Putative exonuclease SbcCD, C subunit
NBLEGCCO_01485 1.6e-304 S amidohydrolase
NBLEGCCO_01486 8.9e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NBLEGCCO_01487 2e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NBLEGCCO_01488 6e-123 S Repeat protein
NBLEGCCO_01489 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NBLEGCCO_01490 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBLEGCCO_01491 4.2e-74 spx4 1.20.4.1 P ArsC family
NBLEGCCO_01492 9.9e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NBLEGCCO_01493 2.2e-31 ykzG S Belongs to the UPF0356 family
NBLEGCCO_01494 2e-74
NBLEGCCO_01495 4.9e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NBLEGCCO_01496 1.2e-48 yktA S Belongs to the UPF0223 family
NBLEGCCO_01497 3.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NBLEGCCO_01498 0.0 typA T GTP-binding protein TypA
NBLEGCCO_01499 8.7e-210 ftsW D Belongs to the SEDS family
NBLEGCCO_01500 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NBLEGCCO_01501 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NBLEGCCO_01502 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NBLEGCCO_01503 2.4e-195 ylbL T Belongs to the peptidase S16 family
NBLEGCCO_01504 3.8e-90 comEA L Competence protein ComEA
NBLEGCCO_01505 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
NBLEGCCO_01506 0.0 comEC S Competence protein ComEC
NBLEGCCO_01507 9.2e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
NBLEGCCO_01508 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
NBLEGCCO_01509 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NBLEGCCO_01510 4.5e-255 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NBLEGCCO_01511 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NBLEGCCO_01512 3.1e-159 S Tetratricopeptide repeat
NBLEGCCO_01513 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NBLEGCCO_01514 3.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NBLEGCCO_01515 5.4e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NBLEGCCO_01516 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NBLEGCCO_01517 9.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NBLEGCCO_01518 0.0 clpL O associated with various cellular activities
NBLEGCCO_01519 1e-34
NBLEGCCO_01520 2e-214 patA 2.6.1.1 E Aminotransferase
NBLEGCCO_01521 2.7e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBLEGCCO_01522 1.2e-182 D Alpha beta
NBLEGCCO_01523 3.4e-188 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NBLEGCCO_01524 4.7e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
NBLEGCCO_01526 8.9e-66 padC Q Phenolic acid decarboxylase
NBLEGCCO_01527 5e-96 padR K Virulence activator alpha C-term
NBLEGCCO_01528 8.4e-78 ndk 2.7.4.6 F Belongs to the NDK family
NBLEGCCO_01529 4.1e-55 S SNARE associated Golgi protein
NBLEGCCO_01530 9.8e-233 N Uncharacterized conserved protein (DUF2075)
NBLEGCCO_01531 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NBLEGCCO_01533 4e-22
NBLEGCCO_01534 1.6e-247 cycA E Amino acid permease
NBLEGCCO_01535 7.4e-85 perR P Belongs to the Fur family
NBLEGCCO_01536 1.5e-248 EGP Major facilitator Superfamily
NBLEGCCO_01537 3.8e-96 tag 3.2.2.20 L glycosylase
NBLEGCCO_01538 5.9e-52
NBLEGCCO_01539 1.2e-208 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NBLEGCCO_01540 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NBLEGCCO_01541 8.8e-110 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NBLEGCCO_01542 7e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
NBLEGCCO_01543 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NBLEGCCO_01544 1.4e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NBLEGCCO_01545 1.4e-122 iolS C Aldo keto reductase
NBLEGCCO_01546 2.4e-116 brnQ U Component of the transport system for branched-chain amino acids
NBLEGCCO_01547 2.5e-56 brnQ U Component of the transport system for branched-chain amino acids
NBLEGCCO_01548 4.4e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBLEGCCO_01549 1.5e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NBLEGCCO_01550 6.4e-96 metI P ABC transporter permease
NBLEGCCO_01551 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NBLEGCCO_01552 3e-148 metQ1 P Belongs to the nlpA lipoprotein family
NBLEGCCO_01553 8.7e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NBLEGCCO_01554 3.5e-272 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NBLEGCCO_01555 6.9e-47
NBLEGCCO_01556 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NBLEGCCO_01557 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NBLEGCCO_01558 9.3e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NBLEGCCO_01559 6.7e-128 stp 3.1.3.16 T phosphatase
NBLEGCCO_01560 0.0 KLT serine threonine protein kinase
NBLEGCCO_01561 5.3e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NBLEGCCO_01562 3.3e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NBLEGCCO_01563 2.3e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
NBLEGCCO_01564 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NBLEGCCO_01565 3.6e-58 asp S Asp23 family, cell envelope-related function
NBLEGCCO_01566 2.1e-302 yloV S DAK2 domain fusion protein YloV
NBLEGCCO_01567 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NBLEGCCO_01568 9e-163 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NBLEGCCO_01569 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBLEGCCO_01570 2.8e-48
NBLEGCCO_01571 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NBLEGCCO_01572 1.2e-260 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NBLEGCCO_01573 3.2e-109 tdk 2.7.1.21 F thymidine kinase
NBLEGCCO_01574 1.2e-154 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NBLEGCCO_01575 3.9e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NBLEGCCO_01576 1.4e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NBLEGCCO_01577 7.8e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBLEGCCO_01578 3.6e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NBLEGCCO_01579 2.3e-180 yibE S overlaps another CDS with the same product name
NBLEGCCO_01580 9.5e-125 yibF S overlaps another CDS with the same product name
NBLEGCCO_01581 5.4e-218 pyrP F Permease
NBLEGCCO_01582 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NBLEGCCO_01583 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBLEGCCO_01584 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NBLEGCCO_01585 4.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBLEGCCO_01586 2.6e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NBLEGCCO_01587 3.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NBLEGCCO_01588 3.7e-252 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NBLEGCCO_01589 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NBLEGCCO_01590 2.8e-29 S Protein of unknown function (DUF1146)
NBLEGCCO_01591 6.6e-216 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
NBLEGCCO_01592 2.6e-183 mbl D Cell shape determining protein MreB Mrl
NBLEGCCO_01593 7.9e-32 S Protein of unknown function (DUF2969)
NBLEGCCO_01594 2.4e-220 rodA D Belongs to the SEDS family
NBLEGCCO_01596 9.3e-178 S Protein of unknown function (DUF2785)
NBLEGCCO_01597 1.2e-213 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NBLEGCCO_01598 6e-199 ypbB 5.1.3.1 S Helix-turn-helix domain
NBLEGCCO_01599 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NBLEGCCO_01600 9.7e-31 M Lysin motif
NBLEGCCO_01601 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NBLEGCCO_01602 1.3e-208 rpsA 1.17.7.4 J Ribosomal protein S1
NBLEGCCO_01603 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NBLEGCCO_01604 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NBLEGCCO_01605 1.8e-234 S Tetratricopeptide repeat protein
NBLEGCCO_01606 7.4e-163 xerD L Phage integrase, N-terminal SAM-like domain
NBLEGCCO_01607 1.2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NBLEGCCO_01608 0.0 yfmR S ABC transporter, ATP-binding protein
NBLEGCCO_01609 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NBLEGCCO_01610 8.7e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NBLEGCCO_01611 1.2e-109 hlyIII S protein, hemolysin III
NBLEGCCO_01612 1.2e-152 DegV S EDD domain protein, DegV family
NBLEGCCO_01613 3.2e-217 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
NBLEGCCO_01614 2.2e-108 cat S Bacterial transferase hexapeptide (six repeats)
NBLEGCCO_01615 4.1e-167 ypmR E lipolytic protein G-D-S-L family
NBLEGCCO_01616 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NBLEGCCO_01617 3.1e-36 yozE S Belongs to the UPF0346 family
NBLEGCCO_01618 3.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NBLEGCCO_01619 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBLEGCCO_01620 8.1e-165 dprA LU DNA protecting protein DprA
NBLEGCCO_01621 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NBLEGCCO_01622 1.6e-154 D DNA integration
NBLEGCCO_01623 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
NBLEGCCO_01624 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NBLEGCCO_01625 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NBLEGCCO_01626 3e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NBLEGCCO_01627 1.1e-204 ecsB U ABC transporter
NBLEGCCO_01628 2.3e-133 ecsA V ABC transporter, ATP-binding protein
NBLEGCCO_01629 1.5e-76 hit FG histidine triad
NBLEGCCO_01631 4.5e-148 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NBLEGCCO_01632 2.8e-179 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
NBLEGCCO_01633 9.8e-56 yheA S Belongs to the UPF0342 family
NBLEGCCO_01634 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NBLEGCCO_01635 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NBLEGCCO_01637 7.2e-35
NBLEGCCO_01639 1e-199 folP 2.5.1.15 H dihydropteroate synthase
NBLEGCCO_01640 5.9e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NBLEGCCO_01641 4.7e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NBLEGCCO_01642 9.8e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NBLEGCCO_01643 9.2e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NBLEGCCO_01644 8.4e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NBLEGCCO_01645 1.1e-119 S CAAX protease self-immunity
NBLEGCCO_01646 2.9e-182 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NBLEGCCO_01647 1.2e-109
NBLEGCCO_01648 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
NBLEGCCO_01649 2.3e-202 rny S Endoribonuclease that initiates mRNA decay
NBLEGCCO_01650 4.5e-129 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NBLEGCCO_01651 3.8e-97 S Pfam:DUF3816
NBLEGCCO_01652 3.6e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NBLEGCCO_01653 7.1e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NBLEGCCO_01654 6.5e-162 EG EamA-like transporter family
NBLEGCCO_01655 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
NBLEGCCO_01657 1.2e-14
NBLEGCCO_01658 2e-152 V ABC transporter, ATP-binding protein
NBLEGCCO_01659 7.8e-64 gntR1 K Transcriptional regulator, GntR family
NBLEGCCO_01660 1.6e-166 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NBLEGCCO_01661 4.2e-88 S Bacterial membrane protein, YfhO
NBLEGCCO_01662 5.9e-212 S Psort location CytoplasmicMembrane, score
NBLEGCCO_01663 3.6e-148 ykoT GT2 M Glycosyl transferase family 2
NBLEGCCO_01664 8.3e-104 glfT1 1.1.1.133 S Glycosyltransferase like family 2
NBLEGCCO_01665 1.3e-95 M transferase activity, transferring glycosyl groups
NBLEGCCO_01666 2.2e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NBLEGCCO_01667 1.8e-165 ykoT GT2 M Glycosyl transferase family 2
NBLEGCCO_01668 1.4e-140 yueF S AI-2E family transporter
NBLEGCCO_01669 3.8e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NBLEGCCO_01670 5.3e-264 ywfO S HD domain protein
NBLEGCCO_01671 3.8e-140 yxeH S hydrolase
NBLEGCCO_01672 9.8e-31
NBLEGCCO_01673 1.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBLEGCCO_01674 6.9e-203 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NBLEGCCO_01675 6.4e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NBLEGCCO_01676 3.2e-128 znuB U ABC 3 transport family
NBLEGCCO_01677 7.3e-92 fhuC P ABC transporter
NBLEGCCO_01678 9.3e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
NBLEGCCO_01679 2.7e-157 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NBLEGCCO_01680 1.8e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NBLEGCCO_01681 5.6e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NBLEGCCO_01682 3.4e-146 tatD L hydrolase, TatD family
NBLEGCCO_01683 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBLEGCCO_01684 4e-161 yunF F Protein of unknown function DUF72
NBLEGCCO_01685 1.9e-209 norA EGP Major facilitator Superfamily
NBLEGCCO_01686 5.5e-124 cobB K SIR2 family
NBLEGCCO_01687 2.5e-186
NBLEGCCO_01688 4.3e-215 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NBLEGCCO_01689 2.8e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NBLEGCCO_01690 0.0 helD 3.6.4.12 L DNA helicase
NBLEGCCO_01691 2.2e-202 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NBLEGCCO_01692 9e-153 metQ_4 P Belongs to the nlpA lipoprotein family
NBLEGCCO_01694 2.8e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NBLEGCCO_01695 2.3e-24 phaG GT1 I carboxylic ester hydrolase activity
NBLEGCCO_01696 1.8e-162 K Transcriptional regulator
NBLEGCCO_01697 7.5e-67 akr5f 1.1.1.346 S reductase
NBLEGCCO_01698 7.9e-27 akr5f 1.1.1.346 S reductase
NBLEGCCO_01699 2.1e-125 S Oxidoreductase, aldo keto reductase family protein
NBLEGCCO_01700 5.6e-26 S Hexapeptide repeat of succinyl-transferase
NBLEGCCO_01701 0.0 pepN 3.4.11.2 E aminopeptidase
NBLEGCCO_01702 8.1e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NBLEGCCO_01703 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
NBLEGCCO_01704 1.6e-134 E GDSL-like Lipase/Acylhydrolase family
NBLEGCCO_01705 8.8e-124 C nitroreductase
NBLEGCCO_01706 3.9e-173 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NBLEGCCO_01707 2.1e-25 arcC 2.7.2.2 E Amino acid kinase family
NBLEGCCO_01708 2.2e-76 arcC 2.7.2.2 E Amino acid kinase family
NBLEGCCO_01709 9.4e-27 S Protein of unknown function (DUF2877)
NBLEGCCO_01710 1e-35 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
NBLEGCCO_01711 1.7e-166 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
NBLEGCCO_01712 2.3e-08 sucD 6.2.1.5 C CoA-ligase
NBLEGCCO_01713 4.6e-177 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBLEGCCO_01714 2.1e-91 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NBLEGCCO_01715 2.7e-48 camS S sex pheromone
NBLEGCCO_01716 6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBLEGCCO_01717 1.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NBLEGCCO_01718 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NBLEGCCO_01719 9.6e-186 yegS 2.7.1.107 G Lipid kinase
NBLEGCCO_01720 1.1e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBLEGCCO_01721 1.5e-221 norB EGP Major Facilitator
NBLEGCCO_01722 3.8e-43 K Bacterial regulatory proteins, tetR family
NBLEGCCO_01724 4.4e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NBLEGCCO_01725 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NBLEGCCO_01726 3.6e-117 dedA S SNARE associated Golgi protein
NBLEGCCO_01727 0.0 helD 3.6.4.12 L DNA helicase
NBLEGCCO_01728 7.3e-161 EG EamA-like transporter family
NBLEGCCO_01729 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NBLEGCCO_01730 1.4e-133 IQ Dehydrogenase reductase
NBLEGCCO_01731 1.8e-101 2.3.1.128 K acetyltransferase
NBLEGCCO_01732 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
NBLEGCCO_01733 3.3e-58 ytzB S Small secreted protein
NBLEGCCO_01734 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NBLEGCCO_01735 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NBLEGCCO_01736 2.1e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NBLEGCCO_01737 6.9e-114 ybhL S Belongs to the BI1 family
NBLEGCCO_01738 3.6e-137 aroD S Serine hydrolase (FSH1)
NBLEGCCO_01739 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NBLEGCCO_01740 4.7e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NBLEGCCO_01741 2.1e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NBLEGCCO_01742 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NBLEGCCO_01743 2e-247 dnaB L replication initiation and membrane attachment
NBLEGCCO_01744 6.2e-171 dnaI L Primosomal protein DnaI
NBLEGCCO_01745 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NBLEGCCO_01746 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NBLEGCCO_01747 1.9e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NBLEGCCO_01748 1.4e-34 yoaK S Protein of unknown function (DUF1275)
NBLEGCCO_01749 5.4e-95 yqeG S HAD phosphatase, family IIIA
NBLEGCCO_01750 1.2e-213 yqeH S Ribosome biogenesis GTPase YqeH
NBLEGCCO_01751 7.6e-49 yhbY J RNA-binding protein
NBLEGCCO_01752 1.2e-93 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NBLEGCCO_01753 4.7e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NBLEGCCO_01754 1.8e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NBLEGCCO_01755 1.3e-134 yqeM Q Methyltransferase
NBLEGCCO_01756 1.3e-212 ylbM S Belongs to the UPF0348 family
NBLEGCCO_01757 2.7e-97 yceD S Uncharacterized ACR, COG1399
NBLEGCCO_01758 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NBLEGCCO_01759 1.6e-120 K response regulator
NBLEGCCO_01760 1.2e-280 arlS 2.7.13.3 T Histidine kinase
NBLEGCCO_01761 1.3e-230 V MatE
NBLEGCCO_01762 1.1e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NBLEGCCO_01763 2.5e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NBLEGCCO_01764 1.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NBLEGCCO_01765 8.3e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBLEGCCO_01766 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NBLEGCCO_01767 7.8e-60 yodB K Transcriptional regulator, HxlR family
NBLEGCCO_01768 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NBLEGCCO_01769 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NBLEGCCO_01770 5.2e-116 udk 2.7.1.48 F Cytidine monophosphokinase
NBLEGCCO_01771 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NBLEGCCO_01772 0.0 S membrane
NBLEGCCO_01773 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NBLEGCCO_01774 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NBLEGCCO_01775 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NBLEGCCO_01776 4.6e-106 gluP 3.4.21.105 S Peptidase, S54 family
NBLEGCCO_01777 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NBLEGCCO_01778 1.7e-179 glk 2.7.1.2 G Glucokinase
NBLEGCCO_01779 1.5e-71 yqhL P Rhodanese-like protein
NBLEGCCO_01780 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
NBLEGCCO_01781 3.7e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NBLEGCCO_01782 3.2e-261 glnA 6.3.1.2 E glutamine synthetase
NBLEGCCO_01783 4.7e-13
NBLEGCCO_01784 9.2e-148
NBLEGCCO_01785 1.6e-174
NBLEGCCO_01786 1.5e-92 dut S Protein conserved in bacteria
NBLEGCCO_01788 1.5e-112 K Transcriptional regulator
NBLEGCCO_01789 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NBLEGCCO_01790 9e-53 ysxB J Cysteine protease Prp
NBLEGCCO_01791 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NBLEGCCO_01792 8.1e-207 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NBLEGCCO_01793 4.1e-72 yqhY S Asp23 family, cell envelope-related function
NBLEGCCO_01794 4.4e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBLEGCCO_01795 5e-159 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NBLEGCCO_01796 1.8e-20
NBLEGCCO_01798 7.1e-195 L Belongs to the 'phage' integrase family
NBLEGCCO_01799 5.2e-13 yttA 2.7.13.3 S Pfam Transposase IS66
NBLEGCCO_01800 1.8e-101 kcsA P Ion transport protein
NBLEGCCO_01802 2.4e-12
NBLEGCCO_01803 8.4e-26 xkdA E Zn peptidase
NBLEGCCO_01804 9.9e-18 3.4.21.88 K Helix-turn-helix
NBLEGCCO_01805 1.1e-07 cro K Helix-turn-helix XRE-family like proteins
NBLEGCCO_01806 2.4e-10 S Domain of unknown function (DUF771)
NBLEGCCO_01809 3.7e-21 S Bacteriophage Mu Gam like protein
NBLEGCCO_01810 3.7e-93 S AAA domain
NBLEGCCO_01811 4.2e-229 res L Helicase C-terminal domain protein
NBLEGCCO_01812 4.2e-106 S Protein of unknown function (DUF669)
NBLEGCCO_01813 0.0 S Phage plasmid primase, P4
NBLEGCCO_01814 5.6e-61 S VRR_NUC
NBLEGCCO_01816 7.5e-10 K Cro/C1-type HTH DNA-binding domain
NBLEGCCO_01820 2.4e-34
NBLEGCCO_01821 2.2e-26 L Terminase small subunit
NBLEGCCO_01823 9.4e-164 S Phage terminase, large subunit
NBLEGCCO_01824 1.4e-208 S Phage portal protein, SPP1 Gp6-like
NBLEGCCO_01825 6.3e-137 S Phage Mu protein F like protein
NBLEGCCO_01826 6.1e-123 bm3R1 K Bacterial regulatory proteins, tetR family
NBLEGCCO_01827 0.0 yhcA V ABC transporter, ATP-binding protein
NBLEGCCO_01828 3.8e-52 S FMN_bind
NBLEGCCO_01829 1e-168 M Membrane
NBLEGCCO_01830 9.3e-24 XK27_06785 V ABC transporter
NBLEGCCO_01831 2.9e-102 K Transcriptional regulator
NBLEGCCO_01832 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NBLEGCCO_01833 3.1e-172 L transposase, IS605 OrfB family
NBLEGCCO_01834 1.3e-63 L Transposase IS200 like
NBLEGCCO_01835 1.4e-242 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBLEGCCO_01836 1.3e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NBLEGCCO_01837 1.4e-259 argH 4.3.2.1 E argininosuccinate lyase
NBLEGCCO_01838 9.6e-80 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBLEGCCO_01839 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NBLEGCCO_01840 1.7e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NBLEGCCO_01841 4.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NBLEGCCO_01842 2.5e-200 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NBLEGCCO_01843 1e-52 C FMN binding
NBLEGCCO_01844 5.9e-219 iscS 2.8.1.7 E Aminotransferase class V
NBLEGCCO_01845 7e-177 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NBLEGCCO_01846 1.4e-54 P Cadmium resistance transporter
NBLEGCCO_01847 2.4e-24 P Cadmium resistance transporter
NBLEGCCO_01848 2.1e-115 S Protein of unknown function (DUF554)
NBLEGCCO_01849 2.2e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBLEGCCO_01850 3e-30 K LysR substrate binding domain
NBLEGCCO_01851 3.3e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NBLEGCCO_01852 9.9e-177 3.4.11.5 E Releases the N-terminal proline from various substrates
NBLEGCCO_01853 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NBLEGCCO_01854 2.3e-206 yfnA E Amino Acid
NBLEGCCO_01855 3.8e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NBLEGCCO_01856 1.8e-104 gmk2 2.7.4.8 F Guanylate kinase
NBLEGCCO_01857 4e-83 zur P Belongs to the Fur family
NBLEGCCO_01859 9.1e-167
NBLEGCCO_01860 1.7e-185 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NBLEGCCO_01861 7.3e-92 K Transcriptional regulator (TetR family)
NBLEGCCO_01862 3.2e-204 V domain protein
NBLEGCCO_01863 5.2e-79
NBLEGCCO_01865 1.1e-186 ydaM M Glycosyl transferase family group 2
NBLEGCCO_01866 1.1e-121 G Glycosyl hydrolases family 8
NBLEGCCO_01867 7.2e-142 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
NBLEGCCO_01868 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBLEGCCO_01869 1.2e-294 ybeC E amino acid
NBLEGCCO_01870 2.3e-93 K Helix-turn-helix domain, rpiR family
NBLEGCCO_01871 1.1e-30 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NBLEGCCO_01872 6.6e-220 lysP E amino acid
NBLEGCCO_01873 0.0 asnB 6.3.5.4 E Asparagine synthase
NBLEGCCO_01874 4.8e-282 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NBLEGCCO_01875 7.6e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NBLEGCCO_01876 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NBLEGCCO_01877 1e-151 F DNA/RNA non-specific endonuclease
NBLEGCCO_01878 3.2e-54 L nuclease
NBLEGCCO_01879 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NBLEGCCO_01880 5.9e-22
NBLEGCCO_01881 2e-278 mntH P H( )-stimulated, divalent metal cation uptake system
NBLEGCCO_01882 2.7e-188 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NBLEGCCO_01883 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
NBLEGCCO_01884 3.9e-158 hrtB V ABC transporter permease
NBLEGCCO_01885 1.4e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NBLEGCCO_01886 7e-75 argR K Regulates arginine biosynthesis genes
NBLEGCCO_01887 2.6e-46 czrA K Transcriptional regulator, ArsR family
NBLEGCCO_01888 8.4e-152 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NBLEGCCO_01890 3.5e-85 K GNAT family
NBLEGCCO_01891 1e-122 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NBLEGCCO_01892 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
NBLEGCCO_01893 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NBLEGCCO_01894 7.3e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NBLEGCCO_01896 3.6e-57
NBLEGCCO_01898 2.3e-07
NBLEGCCO_01899 1.8e-78 K Winged helix DNA-binding domain
NBLEGCCO_01900 0.0 lmrA V ABC transporter, ATP-binding protein
NBLEGCCO_01901 0.0 yfiC V ABC transporter
NBLEGCCO_01902 9.7e-194 ampC V Beta-lactamase
NBLEGCCO_01903 3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBLEGCCO_01904 2.5e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NBLEGCCO_01905 4.4e-164 mepA V MATE efflux family protein
NBLEGCCO_01906 8.5e-56 mepA V MATE efflux family protein
NBLEGCCO_01907 1.6e-224 amtB P ammonium transporter
NBLEGCCO_01908 9.3e-133 XK27_08845 S ABC transporter, ATP-binding protein
NBLEGCCO_01909 3.3e-137 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NBLEGCCO_01910 1.7e-179 ABC-SBP S ABC transporter
NBLEGCCO_01911 1.9e-289 S ABC transporter, ATP-binding protein
NBLEGCCO_01912 2.9e-204 nrnB S DHHA1 domain
NBLEGCCO_01913 1.3e-108 M ErfK YbiS YcfS YnhG
NBLEGCCO_01914 1.3e-75 nrdI F NrdI Flavodoxin like
NBLEGCCO_01915 3.7e-106 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
NBLEGCCO_01916 6.7e-181 1.17.4.1 F Ribonucleotide reductase, small chain
NBLEGCCO_01917 5e-267 S Uncharacterized protein conserved in bacteria (DUF2325)
NBLEGCCO_01918 4.1e-241 dtpT U amino acid peptide transporter
NBLEGCCO_01920 2.1e-211 ydiN G Major Facilitator Superfamily
NBLEGCCO_01921 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
NBLEGCCO_01922 1.2e-61 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NBLEGCCO_01923 1.8e-142 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NBLEGCCO_01924 1.3e-196 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NBLEGCCO_01925 8.7e-90 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NBLEGCCO_01926 1.7e-215 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)