ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDFFNFJJ_00001 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDFFNFJJ_00002 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDFFNFJJ_00003 1.8e-37 yaaB S Domain of unknown function (DUF370)
HDFFNFJJ_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDFFNFJJ_00005 2.4e-33 yaaA S S4 domain
HDFFNFJJ_00006 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDFFNFJJ_00007 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDFFNFJJ_00008 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDFFNFJJ_00009 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDFFNFJJ_00010 6.5e-108 jag S single-stranded nucleic acid binding R3H
HDFFNFJJ_00011 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDFFNFJJ_00012 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDFFNFJJ_00013 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HDFFNFJJ_00014 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HDFFNFJJ_00015 1.5e-74 S Bacterial PH domain
HDFFNFJJ_00016 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HDFFNFJJ_00017 2.1e-149 spo0J K Belongs to the ParB family
HDFFNFJJ_00018 1.6e-111 yyaC S Sporulation protein YyaC
HDFFNFJJ_00019 8.1e-177 yyaD S Membrane
HDFFNFJJ_00020 2.3e-33 yyzM S protein conserved in bacteria
HDFFNFJJ_00021 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDFFNFJJ_00022 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDFFNFJJ_00023 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HDFFNFJJ_00024 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDFFNFJJ_00025 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDFFNFJJ_00026 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
HDFFNFJJ_00027 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HDFFNFJJ_00028 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDFFNFJJ_00029 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HDFFNFJJ_00030 8.5e-246 EGP Major facilitator superfamily
HDFFNFJJ_00031 9.5e-169 yyaK S CAAX protease self-immunity
HDFFNFJJ_00032 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HDFFNFJJ_00033 3.3e-161 yyaM EG EamA-like transporter family
HDFFNFJJ_00034 5.1e-61 yyaN K MerR HTH family regulatory protein
HDFFNFJJ_00035 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
HDFFNFJJ_00036 1.7e-249 tetL EGP Major facilitator Superfamily
HDFFNFJJ_00037 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
HDFFNFJJ_00038 5.4e-67 yyaQ S YjbR
HDFFNFJJ_00039 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
HDFFNFJJ_00040 1.5e-101 yyaS S Membrane
HDFFNFJJ_00041 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
HDFFNFJJ_00042 5.6e-77 yybA 2.3.1.57 K transcriptional
HDFFNFJJ_00043 3e-127 S Metallo-beta-lactamase superfamily
HDFFNFJJ_00044 2.7e-77 yybC
HDFFNFJJ_00045 2e-79 yjcF S Acetyltransferase (GNAT) domain
HDFFNFJJ_00046 2.1e-165 yybE K Transcriptional regulator
HDFFNFJJ_00047 3.2e-220 ynfM EGP Major facilitator Superfamily
HDFFNFJJ_00048 3e-124 yybG S Pentapeptide repeat-containing protein
HDFFNFJJ_00049 5.9e-67 yybH S SnoaL-like domain
HDFFNFJJ_00050 6.2e-132
HDFFNFJJ_00051 2.6e-115 V ATPases associated with a variety of cellular activities
HDFFNFJJ_00052 2e-127 S Protein of unknown function (DUF2705)
HDFFNFJJ_00053 9e-122
HDFFNFJJ_00054 4.1e-125
HDFFNFJJ_00055 1.3e-78 yybN S Protein of unknown function (DUF2712)
HDFFNFJJ_00056 1e-16
HDFFNFJJ_00057 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HDFFNFJJ_00059 1.3e-70
HDFFNFJJ_00060 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HDFFNFJJ_00061 1.4e-68 ydeP3 K Transcriptional regulator
HDFFNFJJ_00062 3.9e-84 cotF M Spore coat protein
HDFFNFJJ_00064 2.9e-160 yybS S membrane
HDFFNFJJ_00065 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDFFNFJJ_00066 2.2e-73 rplI J binds to the 23S rRNA
HDFFNFJJ_00067 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDFFNFJJ_00068 8.4e-221 yeaN P COG2807 Cyanate permease
HDFFNFJJ_00069 1.9e-15 yycC K YycC-like protein
HDFFNFJJ_00071 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HDFFNFJJ_00072 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDFFNFJJ_00073 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDFFNFJJ_00074 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDFFNFJJ_00079 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_00080 0.0 vicK 2.7.13.3 T Histidine kinase
HDFFNFJJ_00081 3.6e-260 yycH S protein conserved in bacteria
HDFFNFJJ_00082 7.3e-155 yycI S protein conserved in bacteria
HDFFNFJJ_00083 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HDFFNFJJ_00084 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDFFNFJJ_00085 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HDFFNFJJ_00086 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HDFFNFJJ_00087 9.7e-261 rocE E amino acid
HDFFNFJJ_00088 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HDFFNFJJ_00090 5e-188 S aspartate phosphatase
HDFFNFJJ_00091 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
HDFFNFJJ_00092 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HDFFNFJJ_00093 1.6e-221 yycP
HDFFNFJJ_00094 2.1e-33 yycQ S Protein of unknown function (DUF2651)
HDFFNFJJ_00096 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HDFFNFJJ_00097 4.2e-71
HDFFNFJJ_00098 1.1e-09 S YyzF-like protein
HDFFNFJJ_00099 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDFFNFJJ_00100 7.3e-280 S Calcineurin-like phosphoesterase
HDFFNFJJ_00101 3.5e-65
HDFFNFJJ_00102 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
HDFFNFJJ_00103 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HDFFNFJJ_00104 8e-12
HDFFNFJJ_00105 7.7e-185 S Radical SAM superfamily
HDFFNFJJ_00106 8.4e-134 yydH O Peptidase M50
HDFFNFJJ_00107 1.8e-110 prrC P ABC transporter
HDFFNFJJ_00108 3.3e-119 S ABC-2 family transporter protein
HDFFNFJJ_00109 7.6e-13
HDFFNFJJ_00110 1.3e-128 yydK K Transcriptional regulator
HDFFNFJJ_00111 2.5e-19 bglF G phosphotransferase system
HDFFNFJJ_00112 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFFNFJJ_00113 3.8e-287 ahpF O Alkyl hydroperoxide reductase
HDFFNFJJ_00114 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HDFFNFJJ_00115 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDFFNFJJ_00116 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HDFFNFJJ_00117 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HDFFNFJJ_00118 7.3e-127 gntR K transcriptional
HDFFNFJJ_00119 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDFFNFJJ_00120 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
HDFFNFJJ_00121 2.6e-118 yxaC M effector of murein hydrolase
HDFFNFJJ_00122 5.2e-50 S LrgA family
HDFFNFJJ_00123 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_00124 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_00125 7.1e-101 yxaF K Transcriptional regulator
HDFFNFJJ_00126 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
HDFFNFJJ_00127 1.4e-228 P Protein of unknown function (DUF418)
HDFFNFJJ_00128 1.1e-75 yxaI S membrane protein domain
HDFFNFJJ_00129 3.5e-65 S Family of unknown function (DUF5391)
HDFFNFJJ_00130 6.8e-93 S PQQ-like domain
HDFFNFJJ_00131 7.6e-214 yxaM U MFS_1 like family
HDFFNFJJ_00132 0.0 asnB 6.3.5.4 E Asparagine synthase
HDFFNFJJ_00133 1.1e-86 yxnB
HDFFNFJJ_00134 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
HDFFNFJJ_00135 3.3e-127 yxbB Q Met-10+ like-protein
HDFFNFJJ_00136 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
HDFFNFJJ_00137 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
HDFFNFJJ_00138 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HDFFNFJJ_00139 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
HDFFNFJJ_00140 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
HDFFNFJJ_00142 0.0 htpG O Molecular chaperone. Has ATPase activity
HDFFNFJJ_00143 2.3e-246 csbC EGP Major facilitator Superfamily
HDFFNFJJ_00144 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HDFFNFJJ_00146 3.7e-176 iolS C Aldo keto reductase
HDFFNFJJ_00147 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HDFFNFJJ_00148 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDFFNFJJ_00149 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HDFFNFJJ_00150 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HDFFNFJJ_00151 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HDFFNFJJ_00152 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HDFFNFJJ_00153 1.3e-235 iolF EGP Major facilitator Superfamily
HDFFNFJJ_00154 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HDFFNFJJ_00155 2.3e-167 iolH G Xylose isomerase-like TIM barrel
HDFFNFJJ_00156 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HDFFNFJJ_00157 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HDFFNFJJ_00158 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_00159 1.3e-182 T PhoQ Sensor
HDFFNFJJ_00160 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HDFFNFJJ_00161 0.0 yxdM V ABC transporter (permease)
HDFFNFJJ_00162 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HDFFNFJJ_00163 6e-177 fhuD P ABC transporter
HDFFNFJJ_00164 8.5e-69
HDFFNFJJ_00165 1.9e-16 yxeD
HDFFNFJJ_00166 1.3e-20 yxeE
HDFFNFJJ_00169 6.2e-151 yidA S hydrolases of the HAD superfamily
HDFFNFJJ_00170 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HDFFNFJJ_00172 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDFFNFJJ_00173 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDFFNFJJ_00174 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HDFFNFJJ_00175 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
HDFFNFJJ_00176 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HDFFNFJJ_00177 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
HDFFNFJJ_00178 2e-255 yxeQ S MmgE/PrpD family
HDFFNFJJ_00179 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
HDFFNFJJ_00180 3e-153 yxxB S Domain of Unknown Function (DUF1206)
HDFFNFJJ_00181 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HDFFNFJJ_00182 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDFFNFJJ_00183 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDFFNFJJ_00184 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HDFFNFJJ_00185 6.1e-252 lysP E amino acid
HDFFNFJJ_00186 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HDFFNFJJ_00187 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HDFFNFJJ_00188 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HDFFNFJJ_00189 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
HDFFNFJJ_00190 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HDFFNFJJ_00191 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HDFFNFJJ_00192 2.1e-21 S Domain of unknown function (DUF5082)
HDFFNFJJ_00193 3.6e-39 yxiC S Family of unknown function (DUF5344)
HDFFNFJJ_00194 0.0 S nuclease activity
HDFFNFJJ_00195 2.2e-78 S SMI1 / KNR4 family
HDFFNFJJ_00196 3.6e-51
HDFFNFJJ_00197 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFFNFJJ_00198 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFFNFJJ_00199 1.1e-72 yxiE T Belongs to the universal stress protein A family
HDFFNFJJ_00200 2.9e-168 yxxF EG EamA-like transporter family
HDFFNFJJ_00201 0.0 wapA M COG3209 Rhs family protein
HDFFNFJJ_00202 1.5e-71 yxxG
HDFFNFJJ_00203 1.7e-84
HDFFNFJJ_00204 6.4e-63
HDFFNFJJ_00205 3.7e-75 yxiG
HDFFNFJJ_00206 4.9e-46
HDFFNFJJ_00207 3.8e-81
HDFFNFJJ_00208 1.2e-96 yxiI S Protein of unknown function (DUF2716)
HDFFNFJJ_00209 1.6e-48 yxiJ S YxiJ-like protein
HDFFNFJJ_00212 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HDFFNFJJ_00213 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HDFFNFJJ_00214 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
HDFFNFJJ_00215 6.6e-114
HDFFNFJJ_00216 8.3e-151 licT K transcriptional antiterminator
HDFFNFJJ_00217 5e-144 exoK GH16 M licheninase activity
HDFFNFJJ_00218 6.6e-224 citH C Citrate transporter
HDFFNFJJ_00219 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HDFFNFJJ_00220 2.7e-48 yxiS
HDFFNFJJ_00221 1.2e-22 T Domain of unknown function (DUF4163)
HDFFNFJJ_00222 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDFFNFJJ_00223 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
HDFFNFJJ_00224 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HDFFNFJJ_00225 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HDFFNFJJ_00226 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HDFFNFJJ_00227 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HDFFNFJJ_00228 1e-220 yxjG 2.1.1.14 E Methionine synthase
HDFFNFJJ_00229 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
HDFFNFJJ_00230 1e-87 yxjI S LURP-one-related
HDFFNFJJ_00233 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDFFNFJJ_00234 8.9e-116 K helix_turn_helix, Lux Regulon
HDFFNFJJ_00235 1.5e-193 yxjM T Signal transduction histidine kinase
HDFFNFJJ_00236 2.4e-78 S Protein of unknown function (DUF1453)
HDFFNFJJ_00237 1.9e-166 yxjO K LysR substrate binding domain
HDFFNFJJ_00238 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
HDFFNFJJ_00239 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDFFNFJJ_00240 4.1e-73 yxkC S Domain of unknown function (DUF4352)
HDFFNFJJ_00241 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDFFNFJJ_00242 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDFFNFJJ_00243 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
HDFFNFJJ_00244 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HDFFNFJJ_00245 3e-156 yxkH G Polysaccharide deacetylase
HDFFNFJJ_00247 0.0 3.4.24.84 O Peptidase family M48
HDFFNFJJ_00248 1.5e-229 cimH C COG3493 Na citrate symporter
HDFFNFJJ_00249 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HDFFNFJJ_00250 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HDFFNFJJ_00251 0.0 cydD V ATP-binding
HDFFNFJJ_00252 0.0 cydD V ATP-binding protein
HDFFNFJJ_00253 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDFFNFJJ_00254 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HDFFNFJJ_00255 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_00256 3.9e-48 yxlC S Family of unknown function (DUF5345)
HDFFNFJJ_00257 1.2e-31
HDFFNFJJ_00258 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HDFFNFJJ_00259 1.5e-166 yxlF V ABC transporter, ATP-binding protein
HDFFNFJJ_00260 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HDFFNFJJ_00261 2.1e-216 yxlH EGP Major facilitator Superfamily
HDFFNFJJ_00262 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HDFFNFJJ_00263 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HDFFNFJJ_00264 1.1e-19 yxzF
HDFFNFJJ_00265 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HDFFNFJJ_00266 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HDFFNFJJ_00267 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDFFNFJJ_00268 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HDFFNFJJ_00269 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HDFFNFJJ_00270 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HDFFNFJJ_00271 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_00272 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDFFNFJJ_00273 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_00274 1.2e-232 dltB M membrane protein involved in D-alanine export
HDFFNFJJ_00275 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_00276 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HDFFNFJJ_00277 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HDFFNFJJ_00278 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HDFFNFJJ_00279 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDFFNFJJ_00280 8.1e-88 ywaE K Transcriptional regulator
HDFFNFJJ_00281 1.7e-128 ywaF S Integral membrane protein
HDFFNFJJ_00282 7e-169 gspA M General stress
HDFFNFJJ_00283 4e-153 sacY K transcriptional antiterminator
HDFFNFJJ_00284 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFFNFJJ_00285 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
HDFFNFJJ_00286 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDFFNFJJ_00287 1.8e-127 ywbB S Protein of unknown function (DUF2711)
HDFFNFJJ_00288 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HDFFNFJJ_00289 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
HDFFNFJJ_00290 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
HDFFNFJJ_00291 1.9e-209 ywbF EGP Major facilitator Superfamily
HDFFNFJJ_00292 2.3e-111 ywbG M effector of murein hydrolase
HDFFNFJJ_00293 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HDFFNFJJ_00294 4.3e-153 ywbI K Transcriptional regulator
HDFFNFJJ_00295 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDFFNFJJ_00296 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDFFNFJJ_00297 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
HDFFNFJJ_00298 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
HDFFNFJJ_00299 2.6e-225 ywbN P Dyp-type peroxidase family protein
HDFFNFJJ_00300 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HDFFNFJJ_00301 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDFFNFJJ_00302 9.8e-49 ywcB S Protein of unknown function, DUF485
HDFFNFJJ_00304 2.2e-122 ywcC K transcriptional regulator
HDFFNFJJ_00305 9.5e-60 gtcA S GtrA-like protein
HDFFNFJJ_00306 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDFFNFJJ_00307 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HDFFNFJJ_00308 1e-35 ywzA S membrane
HDFFNFJJ_00309 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HDFFNFJJ_00310 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HDFFNFJJ_00311 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HDFFNFJJ_00312 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HDFFNFJJ_00313 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HDFFNFJJ_00314 2.9e-202 rodA D Belongs to the SEDS family
HDFFNFJJ_00315 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HDFFNFJJ_00316 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDFFNFJJ_00317 0.0 vpr O Belongs to the peptidase S8 family
HDFFNFJJ_00319 2.4e-150 sacT K transcriptional antiterminator
HDFFNFJJ_00320 1e-139 focA P Formate/nitrite transporter
HDFFNFJJ_00321 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFFNFJJ_00322 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HDFFNFJJ_00323 2e-28 ywdA
HDFFNFJJ_00324 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDFFNFJJ_00325 1.3e-57 pex K Transcriptional regulator PadR-like family
HDFFNFJJ_00326 1.4e-113 ywdD
HDFFNFJJ_00328 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HDFFNFJJ_00329 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDFFNFJJ_00330 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HDFFNFJJ_00331 7.7e-49 ywdI S Family of unknown function (DUF5327)
HDFFNFJJ_00332 1.3e-238 ywdJ F Xanthine uracil
HDFFNFJJ_00333 4.3e-59 ywdK S small membrane protein
HDFFNFJJ_00334 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HDFFNFJJ_00335 2.8e-145 spsA M Spore Coat
HDFFNFJJ_00336 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
HDFFNFJJ_00337 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HDFFNFJJ_00338 4e-164 spsD 2.3.1.210 K Spore Coat
HDFFNFJJ_00339 3.2e-214 spsE 2.5.1.56 M acid synthase
HDFFNFJJ_00340 9.7e-132 spsF M Spore Coat
HDFFNFJJ_00341 1.7e-190 spsG M Spore Coat
HDFFNFJJ_00342 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDFFNFJJ_00343 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDFFNFJJ_00344 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDFFNFJJ_00345 3.5e-87 spsL 5.1.3.13 M Spore Coat
HDFFNFJJ_00346 1.8e-78
HDFFNFJJ_00347 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDFFNFJJ_00348 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HDFFNFJJ_00349 0.0 rocB E arginine degradation protein
HDFFNFJJ_00350 5.1e-251 lysP E amino acid
HDFFNFJJ_00351 4.6e-206 ywfA EGP Major facilitator Superfamily
HDFFNFJJ_00352 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HDFFNFJJ_00353 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HDFFNFJJ_00354 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_00355 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HDFFNFJJ_00356 2.9e-210 bacE EGP Major facilitator Superfamily
HDFFNFJJ_00357 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HDFFNFJJ_00358 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
HDFFNFJJ_00359 1.1e-146 ywfI C May function as heme-dependent peroxidase
HDFFNFJJ_00360 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HDFFNFJJ_00361 9.2e-164 cysL K Transcriptional regulator
HDFFNFJJ_00362 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HDFFNFJJ_00363 5.2e-159 ywfM EG EamA-like transporter family
HDFFNFJJ_00364 1.6e-111 rsfA_1
HDFFNFJJ_00365 3.1e-36 ywzC S Belongs to the UPF0741 family
HDFFNFJJ_00366 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HDFFNFJJ_00367 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HDFFNFJJ_00368 2.8e-79 yffB K Transcriptional regulator
HDFFNFJJ_00369 2.6e-242 mmr U Major Facilitator Superfamily
HDFFNFJJ_00371 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDFFNFJJ_00372 3.3e-71 ywhA K Transcriptional regulator
HDFFNFJJ_00373 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HDFFNFJJ_00374 5.1e-119 ywhC S Peptidase family M50
HDFFNFJJ_00375 5.2e-95 ywhD S YwhD family
HDFFNFJJ_00376 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDFFNFJJ_00377 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HDFFNFJJ_00378 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HDFFNFJJ_00379 1e-84 ywhH S Aminoacyl-tRNA editing domain
HDFFNFJJ_00381 2.3e-79 S aspartate phosphatase
HDFFNFJJ_00382 2.5e-205 ywhK CO amine dehydrogenase activity
HDFFNFJJ_00383 2.9e-249 ywhL CO amine dehydrogenase activity
HDFFNFJJ_00385 1.2e-249 L Peptidase, M16
HDFFNFJJ_00386 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
HDFFNFJJ_00387 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HDFFNFJJ_00388 3.3e-132 cbiO V ABC transporter
HDFFNFJJ_00390 2.6e-271 C Fe-S oxidoreductases
HDFFNFJJ_00391 1e-07 S Bacteriocin subtilosin A
HDFFNFJJ_00392 4.7e-73 ywiB S protein conserved in bacteria
HDFFNFJJ_00393 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HDFFNFJJ_00394 9.8e-214 narK P COG2223 Nitrate nitrite transporter
HDFFNFJJ_00395 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
HDFFNFJJ_00396 4.3e-140 ywiC S YwiC-like protein
HDFFNFJJ_00397 7e-86 arfM T cyclic nucleotide binding
HDFFNFJJ_00398 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDFFNFJJ_00399 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
HDFFNFJJ_00400 2.4e-98 narJ 1.7.5.1 C nitrate reductase
HDFFNFJJ_00401 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
HDFFNFJJ_00402 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDFFNFJJ_00403 0.0 ywjA V ABC transporter
HDFFNFJJ_00404 4.8e-96 ywjB H RibD C-terminal domain
HDFFNFJJ_00405 2.7e-42 ywjC
HDFFNFJJ_00406 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HDFFNFJJ_00407 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HDFFNFJJ_00408 0.0 fadF C COG0247 Fe-S oxidoreductase
HDFFNFJJ_00409 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HDFFNFJJ_00410 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDFFNFJJ_00411 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDFFNFJJ_00412 2.4e-92 ywjG S Domain of unknown function (DUF2529)
HDFFNFJJ_00413 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HDFFNFJJ_00414 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HDFFNFJJ_00415 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDFFNFJJ_00416 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDFFNFJJ_00417 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HDFFNFJJ_00418 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDFFNFJJ_00419 1.1e-32 rpmE J Binds the 23S rRNA
HDFFNFJJ_00420 2.4e-104 tdk 2.7.1.21 F thymidine kinase
HDFFNFJJ_00421 0.0 sfcA 1.1.1.38 C malic enzyme
HDFFNFJJ_00422 8.6e-160 ywkB S Membrane transport protein
HDFFNFJJ_00423 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HDFFNFJJ_00424 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDFFNFJJ_00425 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDFFNFJJ_00426 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDFFNFJJ_00428 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
HDFFNFJJ_00429 6.1e-112 spoIIR S stage II sporulation protein R
HDFFNFJJ_00430 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HDFFNFJJ_00431 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDFFNFJJ_00432 1.7e-91 mntP P Probably functions as a manganese efflux pump
HDFFNFJJ_00433 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDFFNFJJ_00434 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HDFFNFJJ_00435 7.2e-95 ywlG S Belongs to the UPF0340 family
HDFFNFJJ_00436 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDFFNFJJ_00437 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDFFNFJJ_00438 2.5e-62 atpI S ATP synthase
HDFFNFJJ_00439 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HDFFNFJJ_00440 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDFFNFJJ_00441 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDFFNFJJ_00442 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDFFNFJJ_00443 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDFFNFJJ_00444 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDFFNFJJ_00445 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDFFNFJJ_00446 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDFFNFJJ_00447 4.3e-88 ywmA
HDFFNFJJ_00448 1.3e-32 ywzB S membrane
HDFFNFJJ_00449 1.6e-134 ywmB S TATA-box binding
HDFFNFJJ_00450 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDFFNFJJ_00451 2e-178 spoIID D Stage II sporulation protein D
HDFFNFJJ_00452 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HDFFNFJJ_00453 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HDFFNFJJ_00455 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HDFFNFJJ_00456 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HDFFNFJJ_00457 1.3e-103 S response regulator aspartate phosphatase
HDFFNFJJ_00458 3e-84 ywmF S Peptidase M50
HDFFNFJJ_00459 3.8e-11 csbD K CsbD-like
HDFFNFJJ_00461 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HDFFNFJJ_00462 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HDFFNFJJ_00463 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HDFFNFJJ_00464 1.7e-64 ywnA K Transcriptional regulator
HDFFNFJJ_00465 1.6e-114 ywnB S NAD(P)H-binding
HDFFNFJJ_00466 2.6e-59 ywnC S Family of unknown function (DUF5362)
HDFFNFJJ_00467 4.1e-144 mta K transcriptional
HDFFNFJJ_00468 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDFFNFJJ_00469 2.2e-70 ywnF S Family of unknown function (DUF5392)
HDFFNFJJ_00470 2.7e-14 ywnC S Family of unknown function (DUF5362)
HDFFNFJJ_00471 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HDFFNFJJ_00472 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HDFFNFJJ_00473 3.5e-73 ywnJ S VanZ like family
HDFFNFJJ_00474 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HDFFNFJJ_00475 1.6e-58 nrgB K Belongs to the P(II) protein family
HDFFNFJJ_00476 2.5e-225 amt P Ammonium transporter
HDFFNFJJ_00477 1.2e-77
HDFFNFJJ_00478 4e-104 phzA Q Isochorismatase family
HDFFNFJJ_00479 4.4e-242 ywoD EGP Major facilitator superfamily
HDFFNFJJ_00480 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HDFFNFJJ_00481 1.2e-231 ywoF P Right handed beta helix region
HDFFNFJJ_00482 2.7e-211 ywoG EGP Major facilitator Superfamily
HDFFNFJJ_00483 2.1e-70 ywoH K COG1846 Transcriptional regulators
HDFFNFJJ_00484 3e-44 spoIIID K Stage III sporulation protein D
HDFFNFJJ_00485 3.5e-180 mbl D Rod shape-determining protein
HDFFNFJJ_00486 6.9e-126 flhO N flagellar basal body
HDFFNFJJ_00487 1.5e-141 flhP N flagellar basal body
HDFFNFJJ_00488 2.1e-199 S aspartate phosphatase
HDFFNFJJ_00489 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDFFNFJJ_00490 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDFFNFJJ_00491 1.9e-153 ywpD T Histidine kinase
HDFFNFJJ_00492 8e-51 srtA 3.4.22.70 M Sortase family
HDFFNFJJ_00493 1.1e-66 ywpF S YwpF-like protein
HDFFNFJJ_00494 1.3e-66 ywpG
HDFFNFJJ_00495 9.8e-58 ssbB L Single-stranded DNA-binding protein
HDFFNFJJ_00496 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HDFFNFJJ_00497 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HDFFNFJJ_00498 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HDFFNFJJ_00499 3.8e-309 ywqB S SWIM zinc finger
HDFFNFJJ_00500 1.2e-17
HDFFNFJJ_00501 2e-116 ywqC M biosynthesis protein
HDFFNFJJ_00502 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HDFFNFJJ_00503 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HDFFNFJJ_00504 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDFFNFJJ_00505 3.4e-154 ywqG S Domain of unknown function (DUF1963)
HDFFNFJJ_00506 3.3e-15 S Domain of unknown function (DUF5082)
HDFFNFJJ_00507 1.3e-38 ywqI S Family of unknown function (DUF5344)
HDFFNFJJ_00508 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
HDFFNFJJ_00509 1.7e-52 S MORN repeat variant
HDFFNFJJ_00510 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HDFFNFJJ_00511 2.9e-162 K Transcriptional regulator
HDFFNFJJ_00512 2.7e-102 ywqN S NAD(P)H-dependent
HDFFNFJJ_00514 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
HDFFNFJJ_00515 2.4e-104 ywrB P Chromate transporter
HDFFNFJJ_00516 2.1e-82 ywrC K Transcriptional regulator
HDFFNFJJ_00517 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HDFFNFJJ_00518 2.9e-54 S Domain of unknown function (DUF4181)
HDFFNFJJ_00519 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HDFFNFJJ_00520 3.7e-12
HDFFNFJJ_00521 1.2e-210 cotH M Spore Coat
HDFFNFJJ_00522 7.6e-131 cotB
HDFFNFJJ_00523 7.5e-126 ywrJ
HDFFNFJJ_00524 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDFFNFJJ_00525 1.1e-169 alsR K LysR substrate binding domain
HDFFNFJJ_00526 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDFFNFJJ_00527 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HDFFNFJJ_00528 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HDFFNFJJ_00529 3.6e-48 ywsA S Protein of unknown function (DUF3892)
HDFFNFJJ_00530 4.6e-94 batE T Sh3 type 3 domain protein
HDFFNFJJ_00531 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HDFFNFJJ_00532 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HDFFNFJJ_00533 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HDFFNFJJ_00534 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDFFNFJJ_00535 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDFFNFJJ_00536 1.9e-178 rbsR K transcriptional
HDFFNFJJ_00537 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HDFFNFJJ_00538 8.6e-70 pgsC S biosynthesis protein
HDFFNFJJ_00539 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HDFFNFJJ_00540 3.6e-21 ywtC
HDFFNFJJ_00541 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HDFFNFJJ_00542 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HDFFNFJJ_00543 8.4e-171 ywtF K Transcriptional regulator
HDFFNFJJ_00544 1.9e-248 ywtG EGP Major facilitator Superfamily
HDFFNFJJ_00545 7.6e-216 gerAC S Spore germination protein
HDFFNFJJ_00546 7.5e-200 gerBB E Spore germination protein
HDFFNFJJ_00547 3.5e-266 gerBA EG Spore germination protein
HDFFNFJJ_00548 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HDFFNFJJ_00549 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDFFNFJJ_00550 1.2e-260
HDFFNFJJ_00551 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HDFFNFJJ_00552 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDFFNFJJ_00553 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HDFFNFJJ_00554 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HDFFNFJJ_00555 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HDFFNFJJ_00556 1.1e-150 tagG GM Transport permease protein
HDFFNFJJ_00557 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDFFNFJJ_00558 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDFFNFJJ_00560 8.1e-257 ggaA M Glycosyltransferase like family 2
HDFFNFJJ_00561 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDFFNFJJ_00562 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDFFNFJJ_00563 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDFFNFJJ_00564 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HDFFNFJJ_00565 6e-38
HDFFNFJJ_00566 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HDFFNFJJ_00567 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDFFNFJJ_00568 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HDFFNFJJ_00569 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDFFNFJJ_00570 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HDFFNFJJ_00571 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDFFNFJJ_00572 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
HDFFNFJJ_00573 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HDFFNFJJ_00574 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HDFFNFJJ_00575 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HDFFNFJJ_00576 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HDFFNFJJ_00577 6e-163 yvhJ K Transcriptional regulator
HDFFNFJJ_00578 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HDFFNFJJ_00579 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HDFFNFJJ_00580 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDFFNFJJ_00581 7.3e-155 degV S protein conserved in bacteria
HDFFNFJJ_00582 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HDFFNFJJ_00583 5.7e-46 comFB S Late competence development protein ComFB
HDFFNFJJ_00584 2.7e-129 comFC S Phosphoribosyl transferase domain
HDFFNFJJ_00585 7e-74 yvyF S flagellar protein
HDFFNFJJ_00586 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HDFFNFJJ_00587 2.4e-78 flgN NOU FlgN protein
HDFFNFJJ_00588 1.2e-264 flgK N flagellar hook-associated protein
HDFFNFJJ_00589 1.1e-156 flgL N Belongs to the bacterial flagellin family
HDFFNFJJ_00590 2.6e-50 yviE
HDFFNFJJ_00591 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HDFFNFJJ_00592 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HDFFNFJJ_00593 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HDFFNFJJ_00594 6.1e-57 flaG N flagellar protein FlaG
HDFFNFJJ_00595 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HDFFNFJJ_00596 2.9e-69 fliS N flagellar protein FliS
HDFFNFJJ_00597 1.9e-08 fliT S bacterial-type flagellum organization
HDFFNFJJ_00598 2.8e-66
HDFFNFJJ_00599 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDFFNFJJ_00600 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDFFNFJJ_00601 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDFFNFJJ_00602 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HDFFNFJJ_00603 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HDFFNFJJ_00604 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HDFFNFJJ_00605 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HDFFNFJJ_00606 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HDFFNFJJ_00607 5.3e-56 swrA S Swarming motility protein
HDFFNFJJ_00608 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDFFNFJJ_00609 7.9e-228 yvkA EGP Major facilitator Superfamily
HDFFNFJJ_00610 7e-101 yvkB K Transcriptional regulator
HDFFNFJJ_00611 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HDFFNFJJ_00612 1.2e-30 csbA S protein conserved in bacteria
HDFFNFJJ_00613 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDFFNFJJ_00614 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDFFNFJJ_00615 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HDFFNFJJ_00616 6.7e-34 yvkN
HDFFNFJJ_00617 8e-49 yvlA
HDFFNFJJ_00618 3.4e-168 yvlB S Putative adhesin
HDFFNFJJ_00619 2.6e-26 pspB KT PspC domain
HDFFNFJJ_00620 1.2e-50 yvlD S Membrane
HDFFNFJJ_00621 2.7e-203 yvmA EGP Major facilitator Superfamily
HDFFNFJJ_00622 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_00623 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HDFFNFJJ_00624 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
HDFFNFJJ_00625 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_00626 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HDFFNFJJ_00627 3.6e-134 yvoA K transcriptional
HDFFNFJJ_00628 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDFFNFJJ_00629 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDFFNFJJ_00630 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDFFNFJJ_00631 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDFFNFJJ_00632 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
HDFFNFJJ_00633 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HDFFNFJJ_00634 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HDFFNFJJ_00635 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HDFFNFJJ_00636 4.5e-140 yvpB NU protein conserved in bacteria
HDFFNFJJ_00637 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HDFFNFJJ_00638 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDFFNFJJ_00639 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDFFNFJJ_00640 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HDFFNFJJ_00641 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDFFNFJJ_00642 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDFFNFJJ_00643 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDFFNFJJ_00644 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HDFFNFJJ_00645 4.6e-121
HDFFNFJJ_00646 0.0
HDFFNFJJ_00648 0.0 msbA2 3.6.3.44 V ABC transporter
HDFFNFJJ_00649 2.4e-278 S COG0457 FOG TPR repeat
HDFFNFJJ_00650 1.4e-102 usp CBM50 M protein conserved in bacteria
HDFFNFJJ_00651 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDFFNFJJ_00652 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HDFFNFJJ_00653 5.7e-166 rapZ S Displays ATPase and GTPase activities
HDFFNFJJ_00654 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDFFNFJJ_00655 1.4e-170 whiA K May be required for sporulation
HDFFNFJJ_00656 1.6e-36 crh G Phosphocarrier protein Chr
HDFFNFJJ_00657 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HDFFNFJJ_00658 1.8e-33
HDFFNFJJ_00659 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_00660 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HDFFNFJJ_00661 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HDFFNFJJ_00662 0.0 yxdM V ABC transporter (permease)
HDFFNFJJ_00663 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFFNFJJ_00664 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HDFFNFJJ_00665 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HDFFNFJJ_00666 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HDFFNFJJ_00667 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HDFFNFJJ_00668 3.6e-174 yvdE K Transcriptional regulator
HDFFNFJJ_00669 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HDFFNFJJ_00670 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HDFFNFJJ_00671 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
HDFFNFJJ_00672 7.8e-149 malD P transport
HDFFNFJJ_00673 1.2e-158 malA S Protein of unknown function (DUF1189)
HDFFNFJJ_00674 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HDFFNFJJ_00675 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HDFFNFJJ_00676 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HDFFNFJJ_00677 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDFFNFJJ_00679 1.5e-183 S Patatin-like phospholipase
HDFFNFJJ_00680 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
HDFFNFJJ_00681 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
HDFFNFJJ_00682 4.1e-50 sugE P Small Multidrug Resistance protein
HDFFNFJJ_00683 6.7e-51 ykkC P Small Multidrug Resistance protein
HDFFNFJJ_00684 2.6e-106 yvdT K Transcriptional regulator
HDFFNFJJ_00685 1.8e-295 yveA E amino acid
HDFFNFJJ_00686 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HDFFNFJJ_00687 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HDFFNFJJ_00688 9.6e-266 pbpE V Beta-lactamase
HDFFNFJJ_00689 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HDFFNFJJ_00690 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
HDFFNFJJ_00691 4.6e-93 padC Q Phenolic acid decarboxylase
HDFFNFJJ_00693 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HDFFNFJJ_00694 5.7e-77 slr K transcriptional
HDFFNFJJ_00695 4e-122 ywqC M biosynthesis protein
HDFFNFJJ_00696 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HDFFNFJJ_00697 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HDFFNFJJ_00698 2e-224 epsD GT4 M Glycosyl transferase 4-like
HDFFNFJJ_00699 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDFFNFJJ_00700 5.3e-220 epsF GT4 M Glycosyl transferases group 1
HDFFNFJJ_00701 4.8e-207 epsG S EpsG family
HDFFNFJJ_00702 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
HDFFNFJJ_00703 3.6e-207 epsI GM pyruvyl transferase
HDFFNFJJ_00704 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HDFFNFJJ_00705 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDFFNFJJ_00706 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HDFFNFJJ_00707 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HDFFNFJJ_00708 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HDFFNFJJ_00709 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
HDFFNFJJ_00710 1e-31 yvfG S YvfG protein
HDFFNFJJ_00711 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HDFFNFJJ_00712 1.4e-309 yvfH C L-lactate permease
HDFFNFJJ_00713 1e-112 yvfI K COG2186 Transcriptional regulators
HDFFNFJJ_00714 1.8e-184 lacR K Transcriptional regulator
HDFFNFJJ_00715 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
HDFFNFJJ_00716 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HDFFNFJJ_00717 3.2e-150 ganQ P transport
HDFFNFJJ_00718 0.0 lacA 3.2.1.23 G beta-galactosidase
HDFFNFJJ_00719 2.6e-252 galA 3.2.1.89 G arabinogalactan
HDFFNFJJ_00720 1.4e-199 rsbU 3.1.3.3 T response regulator
HDFFNFJJ_00721 2.6e-157 rsbQ S Alpha/beta hydrolase family
HDFFNFJJ_00722 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HDFFNFJJ_00723 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
HDFFNFJJ_00724 8.9e-201 desK 2.7.13.3 T Histidine kinase
HDFFNFJJ_00725 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDFFNFJJ_00726 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HDFFNFJJ_00727 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HDFFNFJJ_00728 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HDFFNFJJ_00729 4.3e-197 yvbX S Glycosyl hydrolase
HDFFNFJJ_00730 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HDFFNFJJ_00731 8.5e-157 yvbV EG EamA-like transporter family
HDFFNFJJ_00732 3.9e-159 yvbU K Transcriptional regulator
HDFFNFJJ_00733 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDFFNFJJ_00734 5.5e-203 araR K transcriptional
HDFFNFJJ_00735 1.6e-252 araE EGP Major facilitator Superfamily
HDFFNFJJ_00736 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HDFFNFJJ_00737 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDFFNFJJ_00738 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDFFNFJJ_00739 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDFFNFJJ_00740 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HDFFNFJJ_00741 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDFFNFJJ_00742 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
HDFFNFJJ_00743 0.0 tcaA S response to antibiotic
HDFFNFJJ_00744 4.2e-124 exoY M Membrane
HDFFNFJJ_00745 8.6e-113 yvbH S YvbH-like oligomerisation region
HDFFNFJJ_00746 6.4e-103 yvbG U UPF0056 membrane protein
HDFFNFJJ_00747 1.4e-98 yvbF K Belongs to the GbsR family
HDFFNFJJ_00748 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HDFFNFJJ_00749 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HDFFNFJJ_00750 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDFFNFJJ_00751 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HDFFNFJJ_00752 4.5e-45 sdpR K transcriptional
HDFFNFJJ_00753 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HDFFNFJJ_00754 4.4e-08
HDFFNFJJ_00755 7.6e-172
HDFFNFJJ_00756 7.9e-13 S Sporulation delaying protein SdpA
HDFFNFJJ_00757 8.7e-61 yvbF K Belongs to the GbsR family
HDFFNFJJ_00758 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HDFFNFJJ_00759 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HDFFNFJJ_00760 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDFFNFJJ_00761 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HDFFNFJJ_00762 4.2e-226 NT chemotaxis protein
HDFFNFJJ_00763 2.2e-54 yodB K transcriptional
HDFFNFJJ_00764 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
HDFFNFJJ_00765 4e-69 K transcriptional
HDFFNFJJ_00766 7.5e-36 yvzC K Transcriptional
HDFFNFJJ_00767 3.7e-153 yvaM S Serine aminopeptidase, S33
HDFFNFJJ_00768 2.4e-23 secG U Preprotein translocase subunit SecG
HDFFNFJJ_00769 5.6e-143 est 3.1.1.1 S Carboxylesterase
HDFFNFJJ_00770 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDFFNFJJ_00771 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HDFFNFJJ_00773 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_00774 4.1e-101 K Bacterial regulatory proteins, tetR family
HDFFNFJJ_00775 2.8e-55 yvaE P Small Multidrug Resistance protein
HDFFNFJJ_00776 5.7e-73 yvaD S Family of unknown function (DUF5360)
HDFFNFJJ_00777 0.0 yvaC S Fusaric acid resistance protein-like
HDFFNFJJ_00778 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDFFNFJJ_00779 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
HDFFNFJJ_00780 2.2e-48 csoR S transcriptional
HDFFNFJJ_00781 1.5e-29 copZ P Copper resistance protein CopZ
HDFFNFJJ_00782 0.0 copA 3.6.3.54 P P-type ATPase
HDFFNFJJ_00783 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HDFFNFJJ_00784 1.6e-104 bdbD O Thioredoxin
HDFFNFJJ_00785 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HDFFNFJJ_00786 4.1e-107 yvgT S membrane
HDFFNFJJ_00787 0.0 helD 3.6.4.12 L DNA helicase
HDFFNFJJ_00788 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HDFFNFJJ_00789 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HDFFNFJJ_00790 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HDFFNFJJ_00791 5.4e-86 yvgO
HDFFNFJJ_00792 9.1e-158 yvgN S reductase
HDFFNFJJ_00793 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
HDFFNFJJ_00794 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HDFFNFJJ_00795 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HDFFNFJJ_00796 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDFFNFJJ_00797 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HDFFNFJJ_00798 6.5e-16 S Small spore protein J (Spore_SspJ)
HDFFNFJJ_00799 2.6e-237 yvsH E Arginine ornithine antiporter
HDFFNFJJ_00801 2.1e-179 fhuD P ABC transporter
HDFFNFJJ_00802 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_00803 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_00804 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HDFFNFJJ_00805 4.8e-176 M Efflux transporter rnd family, mfp subunit
HDFFNFJJ_00806 7.1e-124 macB V ABC transporter, ATP-binding protein
HDFFNFJJ_00807 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HDFFNFJJ_00808 1.3e-64 yvrL S Regulatory protein YrvL
HDFFNFJJ_00809 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
HDFFNFJJ_00810 2.4e-19 S YvrJ protein family
HDFFNFJJ_00811 1.8e-96 yvrI K RNA polymerase
HDFFNFJJ_00812 3.6e-22
HDFFNFJJ_00813 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_00814 0.0 T PhoQ Sensor
HDFFNFJJ_00815 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HDFFNFJJ_00816 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_00817 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HDFFNFJJ_00818 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_00819 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HDFFNFJJ_00820 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
HDFFNFJJ_00821 4.8e-227 yvqJ EGP Major facilitator Superfamily
HDFFNFJJ_00822 5.6e-62 liaI S membrane
HDFFNFJJ_00823 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HDFFNFJJ_00824 9.3e-129 liaG S Putative adhesin
HDFFNFJJ_00825 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HDFFNFJJ_00826 5.5e-187 vraS 2.7.13.3 T Histidine kinase
HDFFNFJJ_00827 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDFFNFJJ_00828 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
HDFFNFJJ_00829 9.1e-198 gerAB E Spore germination protein
HDFFNFJJ_00830 2.2e-247 gerAA EG Spore germination protein
HDFFNFJJ_00831 2.3e-24 S Protein of unknown function (DUF3970)
HDFFNFJJ_00832 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDFFNFJJ_00833 4.3e-158 yuxN K Transcriptional regulator
HDFFNFJJ_00834 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HDFFNFJJ_00835 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_00836 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDFFNFJJ_00837 1.2e-79 dps P Ferritin-like domain
HDFFNFJJ_00838 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_00839 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
HDFFNFJJ_00840 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
HDFFNFJJ_00841 5.6e-66 S YusW-like protein
HDFFNFJJ_00842 1e-153 yusV 3.6.3.34 HP ABC transporter
HDFFNFJJ_00843 3.8e-47 yusU S Protein of unknown function (DUF2573)
HDFFNFJJ_00844 2.7e-160 yusT K LysR substrate binding domain
HDFFNFJJ_00845 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_00846 1e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_00847 8.4e-66 yusQ S Tautomerase enzyme
HDFFNFJJ_00848 3.8e-293 yusP P Major facilitator superfamily
HDFFNFJJ_00849 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
HDFFNFJJ_00850 3.2e-53 yusN M Coat F domain
HDFFNFJJ_00851 5.1e-40
HDFFNFJJ_00852 2.2e-165 fadM E Proline dehydrogenase
HDFFNFJJ_00853 4.7e-09 S YuzL-like protein
HDFFNFJJ_00854 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HDFFNFJJ_00855 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HDFFNFJJ_00856 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HDFFNFJJ_00857 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HDFFNFJJ_00858 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HDFFNFJJ_00859 1.1e-39 yusG S Protein of unknown function (DUF2553)
HDFFNFJJ_00860 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HDFFNFJJ_00861 5.6e-55 traF CO Thioredoxin
HDFFNFJJ_00862 2.4e-56 yusD S SCP-2 sterol transfer family
HDFFNFJJ_00863 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDFFNFJJ_00864 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HDFFNFJJ_00865 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
HDFFNFJJ_00866 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HDFFNFJJ_00867 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HDFFNFJJ_00868 1.4e-245 sufD O assembly protein SufD
HDFFNFJJ_00869 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDFFNFJJ_00870 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HDFFNFJJ_00871 3.5e-271 sufB O FeS cluster assembly
HDFFNFJJ_00872 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDFFNFJJ_00873 1e-41
HDFFNFJJ_00875 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HDFFNFJJ_00876 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HDFFNFJJ_00877 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HDFFNFJJ_00878 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HDFFNFJJ_00879 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
HDFFNFJJ_00880 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HDFFNFJJ_00881 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HDFFNFJJ_00882 1.1e-135 yurK K UTRA
HDFFNFJJ_00883 1.2e-205 msmX P Belongs to the ABC transporter superfamily
HDFFNFJJ_00884 2.4e-169 bsn L Ribonuclease
HDFFNFJJ_00885 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HDFFNFJJ_00886 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HDFFNFJJ_00888 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HDFFNFJJ_00889 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HDFFNFJJ_00890 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HDFFNFJJ_00891 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HDFFNFJJ_00892 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HDFFNFJJ_00893 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HDFFNFJJ_00894 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HDFFNFJJ_00895 1.3e-224 pbuX F xanthine
HDFFNFJJ_00896 2.1e-236 pbuX F Permease family
HDFFNFJJ_00897 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HDFFNFJJ_00898 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HDFFNFJJ_00899 3e-62 yunG
HDFFNFJJ_00900 4.3e-171 yunF S Protein of unknown function DUF72
HDFFNFJJ_00901 2e-141 yunE S membrane transporter protein
HDFFNFJJ_00902 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDFFNFJJ_00903 4.8e-48 yunC S Domain of unknown function (DUF1805)
HDFFNFJJ_00904 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
HDFFNFJJ_00905 4.5e-196 lytH M Peptidase, M23
HDFFNFJJ_00906 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HDFFNFJJ_00907 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDFFNFJJ_00908 9.7e-48 yutD S protein conserved in bacteria
HDFFNFJJ_00909 1e-75 yutE S Protein of unknown function DUF86
HDFFNFJJ_00910 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDFFNFJJ_00911 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HDFFNFJJ_00912 2e-199 yutH S Spore coat protein
HDFFNFJJ_00913 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HDFFNFJJ_00914 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HDFFNFJJ_00915 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDFFNFJJ_00916 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HDFFNFJJ_00917 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HDFFNFJJ_00918 3.5e-57 yuzD S protein conserved in bacteria
HDFFNFJJ_00919 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HDFFNFJJ_00920 3.2e-39 yuzB S Belongs to the UPF0349 family
HDFFNFJJ_00921 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDFFNFJJ_00922 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDFFNFJJ_00923 3.7e-63 erpA S Belongs to the HesB IscA family
HDFFNFJJ_00924 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDFFNFJJ_00925 9e-118 paiB K Putative FMN-binding domain
HDFFNFJJ_00926 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDFFNFJJ_00928 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HDFFNFJJ_00929 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HDFFNFJJ_00930 8.4e-27 yuiB S Putative membrane protein
HDFFNFJJ_00931 5.6e-118 yuiC S protein conserved in bacteria
HDFFNFJJ_00932 1.2e-77 yuiD S protein conserved in bacteria
HDFFNFJJ_00933 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HDFFNFJJ_00934 3.9e-211 yuiF S antiporter
HDFFNFJJ_00935 1.1e-93 bioY S Biotin biosynthesis protein
HDFFNFJJ_00936 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HDFFNFJJ_00937 1.3e-167 besA S Putative esterase
HDFFNFJJ_00938 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_00939 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
HDFFNFJJ_00940 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HDFFNFJJ_00941 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HDFFNFJJ_00942 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_00943 3.8e-36 mbtH S MbtH-like protein
HDFFNFJJ_00944 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HDFFNFJJ_00945 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HDFFNFJJ_00946 6.5e-229 yukF QT Transcriptional regulator
HDFFNFJJ_00947 2.8e-45 esxA S Belongs to the WXG100 family
HDFFNFJJ_00948 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HDFFNFJJ_00949 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HDFFNFJJ_00950 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HDFFNFJJ_00951 0.0 esaA S type VII secretion protein EsaA
HDFFNFJJ_00952 6.6e-65 yueC S Family of unknown function (DUF5383)
HDFFNFJJ_00953 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_00954 4.8e-96 yueE S phosphohydrolase
HDFFNFJJ_00955 2.9e-24 S Protein of unknown function (DUF2642)
HDFFNFJJ_00956 6.1e-72 S Protein of unknown function (DUF2283)
HDFFNFJJ_00957 1.9e-190 yueF S transporter activity
HDFFNFJJ_00958 2.1e-32 yueG S Spore germination protein gerPA/gerPF
HDFFNFJJ_00959 7.4e-39 yueH S YueH-like protein
HDFFNFJJ_00960 1.6e-67 yueI S Protein of unknown function (DUF1694)
HDFFNFJJ_00961 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
HDFFNFJJ_00962 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDFFNFJJ_00963 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HDFFNFJJ_00964 1.1e-22 yuzC
HDFFNFJJ_00966 2.5e-162 comQ H Polyprenyl synthetase
HDFFNFJJ_00968 0.0 comP 2.7.13.3 T Histidine kinase
HDFFNFJJ_00969 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDFFNFJJ_00970 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HDFFNFJJ_00971 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HDFFNFJJ_00972 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDFFNFJJ_00973 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDFFNFJJ_00974 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDFFNFJJ_00975 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDFFNFJJ_00976 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDFFNFJJ_00977 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HDFFNFJJ_00978 1.9e-14
HDFFNFJJ_00979 1.3e-233 maeN C COG3493 Na citrate symporter
HDFFNFJJ_00980 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HDFFNFJJ_00981 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HDFFNFJJ_00982 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HDFFNFJJ_00983 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HDFFNFJJ_00984 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HDFFNFJJ_00985 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HDFFNFJJ_00986 6.3e-78 yufK S Family of unknown function (DUF5366)
HDFFNFJJ_00987 6.3e-75 yuxK S protein conserved in bacteria
HDFFNFJJ_00988 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HDFFNFJJ_00989 3.5e-186 yuxJ EGP Major facilitator Superfamily
HDFFNFJJ_00991 1.9e-115 kapD L the KinA pathway to sporulation
HDFFNFJJ_00992 2e-70 kapB G Kinase associated protein B
HDFFNFJJ_00993 4.6e-233 T PhoQ Sensor
HDFFNFJJ_00994 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HDFFNFJJ_00995 9.8e-42 yugE S Domain of unknown function (DUF1871)
HDFFNFJJ_00996 1e-156 yugF I Hydrolase
HDFFNFJJ_00997 1.6e-85 alaR K Transcriptional regulator
HDFFNFJJ_00998 4.3e-200 yugH 2.6.1.1 E Aminotransferase
HDFFNFJJ_00999 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HDFFNFJJ_01000 1.1e-34 yuzA S Domain of unknown function (DUF378)
HDFFNFJJ_01001 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HDFFNFJJ_01002 2.8e-229 yugK C Dehydrogenase
HDFFNFJJ_01003 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HDFFNFJJ_01005 1.3e-72 yugN S YugN-like family
HDFFNFJJ_01006 1.7e-182 yugO P COG1226 Kef-type K transport systems
HDFFNFJJ_01007 1.1e-53 mstX S Membrane-integrating protein Mistic
HDFFNFJJ_01008 4.6e-39
HDFFNFJJ_01009 1.4e-116 yugP S Zn-dependent protease
HDFFNFJJ_01010 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HDFFNFJJ_01011 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HDFFNFJJ_01012 2.1e-72 yugU S Uncharacterised protein family UPF0047
HDFFNFJJ_01013 1e-35
HDFFNFJJ_01014 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HDFFNFJJ_01015 3.2e-225 mcpA NT chemotaxis protein
HDFFNFJJ_01016 1.5e-222 mcpA NT chemotaxis protein
HDFFNFJJ_01017 2.2e-295 mcpA NT chemotaxis protein
HDFFNFJJ_01018 5.1e-239 mcpA NT chemotaxis protein
HDFFNFJJ_01019 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HDFFNFJJ_01020 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HDFFNFJJ_01021 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HDFFNFJJ_01022 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HDFFNFJJ_01023 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HDFFNFJJ_01024 3.3e-183 ygjR S Oxidoreductase
HDFFNFJJ_01025 6.3e-197 yubA S transporter activity
HDFFNFJJ_01026 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDFFNFJJ_01028 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HDFFNFJJ_01029 6.2e-277 yubD P Major Facilitator Superfamily
HDFFNFJJ_01030 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDFFNFJJ_01031 1e-38 yiaA S yiaA/B two helix domain
HDFFNFJJ_01032 5.4e-237 ktrB P Potassium
HDFFNFJJ_01033 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
HDFFNFJJ_01034 2.2e-91 yuaB
HDFFNFJJ_01035 1.1e-95 yuaC K Belongs to the GbsR family
HDFFNFJJ_01036 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HDFFNFJJ_01037 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HDFFNFJJ_01038 7.9e-108 yuaD
HDFFNFJJ_01039 3.9e-84 yuaE S DinB superfamily
HDFFNFJJ_01040 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HDFFNFJJ_01041 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HDFFNFJJ_01042 3.4e-94 M1-753 M FR47-like protein
HDFFNFJJ_01043 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HDFFNFJJ_01044 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HDFFNFJJ_01045 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HDFFNFJJ_01046 1.2e-84 gerD
HDFFNFJJ_01047 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HDFFNFJJ_01048 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDFFNFJJ_01049 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HDFFNFJJ_01050 8.2e-145 ybaJ Q Methyltransferase domain
HDFFNFJJ_01051 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HDFFNFJJ_01052 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDFFNFJJ_01053 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDFFNFJJ_01054 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDFFNFJJ_01055 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDFFNFJJ_01056 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDFFNFJJ_01057 3.6e-58 rplQ J Ribosomal protein L17
HDFFNFJJ_01058 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDFFNFJJ_01059 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDFFNFJJ_01060 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDFFNFJJ_01061 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HDFFNFJJ_01062 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDFFNFJJ_01063 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HDFFNFJJ_01064 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDFFNFJJ_01065 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDFFNFJJ_01066 1.8e-72 rplO J binds to the 23S rRNA
HDFFNFJJ_01067 1.9e-23 rpmD J Ribosomal protein L30
HDFFNFJJ_01068 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDFFNFJJ_01069 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDFFNFJJ_01070 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDFFNFJJ_01071 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDFFNFJJ_01072 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDFFNFJJ_01073 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDFFNFJJ_01074 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDFFNFJJ_01075 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDFFNFJJ_01076 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDFFNFJJ_01077 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HDFFNFJJ_01078 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDFFNFJJ_01079 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDFFNFJJ_01080 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDFFNFJJ_01081 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDFFNFJJ_01082 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDFFNFJJ_01083 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDFFNFJJ_01084 3e-105 rplD J Forms part of the polypeptide exit tunnel
HDFFNFJJ_01085 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDFFNFJJ_01086 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HDFFNFJJ_01087 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HDFFNFJJ_01088 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDFFNFJJ_01089 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDFFNFJJ_01090 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDFFNFJJ_01091 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDFFNFJJ_01092 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HDFFNFJJ_01093 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDFFNFJJ_01094 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDFFNFJJ_01095 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HDFFNFJJ_01096 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDFFNFJJ_01097 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDFFNFJJ_01098 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDFFNFJJ_01099 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDFFNFJJ_01100 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HDFFNFJJ_01101 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDFFNFJJ_01102 4.4e-115 sigH K Belongs to the sigma-70 factor family
HDFFNFJJ_01103 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HDFFNFJJ_01104 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDFFNFJJ_01105 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDFFNFJJ_01106 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDFFNFJJ_01107 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HDFFNFJJ_01108 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDFFNFJJ_01109 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HDFFNFJJ_01110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HDFFNFJJ_01111 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HDFFNFJJ_01112 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HDFFNFJJ_01113 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDFFNFJJ_01114 0.0 clpC O Belongs to the ClpA ClpB family
HDFFNFJJ_01115 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HDFFNFJJ_01116 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HDFFNFJJ_01117 2.9e-76 ctsR K Belongs to the CtsR family
HDFFNFJJ_01118 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDFFNFJJ_01119 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDFFNFJJ_01120 4.1e-30 yazB K transcriptional
HDFFNFJJ_01121 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HDFFNFJJ_01122 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDFFNFJJ_01123 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HDFFNFJJ_01124 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HDFFNFJJ_01125 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HDFFNFJJ_01126 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDFFNFJJ_01127 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDFFNFJJ_01128 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HDFFNFJJ_01129 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDFFNFJJ_01130 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HDFFNFJJ_01131 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDFFNFJJ_01132 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDFFNFJJ_01133 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDFFNFJJ_01134 6.7e-187 KLT serine threonine protein kinase
HDFFNFJJ_01135 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HDFFNFJJ_01136 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HDFFNFJJ_01139 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HDFFNFJJ_01140 1.1e-44 divIC D Septum formation initiator
HDFFNFJJ_01141 3.9e-108 yabQ S spore cortex biosynthesis protein
HDFFNFJJ_01142 1.5e-49 yabP S Sporulation protein YabP
HDFFNFJJ_01143 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HDFFNFJJ_01144 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HDFFNFJJ_01145 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDFFNFJJ_01146 1.5e-92 spoVT K stage V sporulation protein
HDFFNFJJ_01147 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDFFNFJJ_01148 2.4e-39 yabK S Peptide ABC transporter permease
HDFFNFJJ_01149 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDFFNFJJ_01150 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HDFFNFJJ_01151 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDFFNFJJ_01152 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDFFNFJJ_01153 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HDFFNFJJ_01154 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HDFFNFJJ_01155 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HDFFNFJJ_01156 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDFFNFJJ_01157 8.3e-27 sspF S DNA topological change
HDFFNFJJ_01158 7.8e-39 veg S protein conserved in bacteria
HDFFNFJJ_01159 3.3e-137 yabG S peptidase
HDFFNFJJ_01160 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDFFNFJJ_01161 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDFFNFJJ_01162 4.3e-194 rpfB GH23 T protein conserved in bacteria
HDFFNFJJ_01163 1.8e-144 tatD L hydrolase, TatD
HDFFNFJJ_01164 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDFFNFJJ_01165 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HDFFNFJJ_01166 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDFFNFJJ_01167 1.5e-49 yazA L endonuclease containing a URI domain
HDFFNFJJ_01168 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HDFFNFJJ_01169 4.8e-31 yabA L Involved in initiation control of chromosome replication
HDFFNFJJ_01170 2.1e-146 yaaT S stage 0 sporulation protein
HDFFNFJJ_01171 2.2e-182 holB 2.7.7.7 L DNA polymerase III
HDFFNFJJ_01172 1.5e-71 yaaR S protein conserved in bacteria
HDFFNFJJ_01173 2.2e-54 yaaQ S protein conserved in bacteria
HDFFNFJJ_01174 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDFFNFJJ_01175 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HDFFNFJJ_01176 4.5e-203 yaaN P Belongs to the TelA family
HDFFNFJJ_01177 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HDFFNFJJ_01178 3.4e-31 csfB S Inhibitor of sigma-G Gin
HDFFNFJJ_01179 2.7e-182 yaaC S YaaC-like Protein
HDFFNFJJ_01180 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HDFFNFJJ_01181 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDFFNFJJ_01182 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HDFFNFJJ_01183 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HDFFNFJJ_01184 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDFFNFJJ_01185 1.3e-09
HDFFNFJJ_01186 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HDFFNFJJ_01187 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HDFFNFJJ_01188 5.6e-215 yaaH M Glycoside Hydrolase Family
HDFFNFJJ_01189 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
HDFFNFJJ_01190 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDFFNFJJ_01191 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDFFNFJJ_01192 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDFFNFJJ_01193 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDFFNFJJ_01194 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HDFFNFJJ_01195 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HDFFNFJJ_01196 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_01197 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_01198 8.3e-96 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_01199 3.4e-39 S COG NOG14552 non supervised orthologous group
HDFFNFJJ_01204 2e-08
HDFFNFJJ_01212 2e-08
HDFFNFJJ_01217 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_01218 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_01219 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HDFFNFJJ_01220 2.8e-64 yngL S Protein of unknown function (DUF1360)
HDFFNFJJ_01221 1.3e-306 yngK T Glycosyl hydrolase-like 10
HDFFNFJJ_01222 1.8e-31 S Family of unknown function (DUF5367)
HDFFNFJJ_01223 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HDFFNFJJ_01224 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HDFFNFJJ_01225 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HDFFNFJJ_01226 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HDFFNFJJ_01227 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HDFFNFJJ_01228 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HDFFNFJJ_01229 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HDFFNFJJ_01230 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
HDFFNFJJ_01231 5.5e-104 yngC S membrane-associated protein
HDFFNFJJ_01232 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDFFNFJJ_01233 2.4e-80 yngA S membrane
HDFFNFJJ_01234 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HDFFNFJJ_01235 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HDFFNFJJ_01237 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HDFFNFJJ_01238 8.2e-252 agcS E Sodium alanine symporter
HDFFNFJJ_01239 1.3e-57 ynfC
HDFFNFJJ_01240 2.3e-12
HDFFNFJJ_01241 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDFFNFJJ_01242 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDFFNFJJ_01243 6.6e-69 yccU S CoA-binding protein
HDFFNFJJ_01244 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDFFNFJJ_01245 4.1e-49 yneR S Belongs to the HesB IscA family
HDFFNFJJ_01246 1.3e-53 yneQ
HDFFNFJJ_01247 1.2e-73 yneP S Thioesterase-like superfamily
HDFFNFJJ_01248 3.9e-35 tlp S Belongs to the Tlp family
HDFFNFJJ_01249 3.1e-08 sspN S Small acid-soluble spore protein N family
HDFFNFJJ_01251 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HDFFNFJJ_01252 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HDFFNFJJ_01253 2.2e-14 sspO S Belongs to the SspO family
HDFFNFJJ_01254 3.9e-19 sspP S Belongs to the SspP family
HDFFNFJJ_01255 4.1e-65 hspX O Spore coat protein
HDFFNFJJ_01256 4.2e-74 yneK S Protein of unknown function (DUF2621)
HDFFNFJJ_01257 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HDFFNFJJ_01258 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HDFFNFJJ_01259 7.1e-127 ccdA O cytochrome c biogenesis protein
HDFFNFJJ_01260 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HDFFNFJJ_01261 1.8e-28 yneF S UPF0154 protein
HDFFNFJJ_01262 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HDFFNFJJ_01263 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDFFNFJJ_01264 1.3e-32 ynzC S UPF0291 protein
HDFFNFJJ_01265 9.2e-113 yneB L resolvase
HDFFNFJJ_01266 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HDFFNFJJ_01267 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDFFNFJJ_01269 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HDFFNFJJ_01270 5.8e-74 yndM S Protein of unknown function (DUF2512)
HDFFNFJJ_01271 8.6e-139 yndL S Replication protein
HDFFNFJJ_01273 0.0 yndJ S YndJ-like protein
HDFFNFJJ_01274 2.6e-117 yndH S Domain of unknown function (DUF4166)
HDFFNFJJ_01275 7.7e-154 yndG S DoxX-like family
HDFFNFJJ_01276 4.2e-220 gerLC S Spore germination protein
HDFFNFJJ_01277 4.5e-197 gerAB U Spore germination
HDFFNFJJ_01278 5.7e-286 gerAA EG Spore germination protein
HDFFNFJJ_01281 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HDFFNFJJ_01282 1.8e-71
HDFFNFJJ_01283 7.9e-25 tatA U protein secretion
HDFFNFJJ_01286 1.3e-134 S Domain of unknown function, YrpD
HDFFNFJJ_01288 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDFFNFJJ_01291 5.2e-15
HDFFNFJJ_01292 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HDFFNFJJ_01293 6.3e-84 yncE S Protein of unknown function (DUF2691)
HDFFNFJJ_01294 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDFFNFJJ_01295 3.5e-247 iolT EGP Major facilitator Superfamily
HDFFNFJJ_01296 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
HDFFNFJJ_01297 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HDFFNFJJ_01298 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HDFFNFJJ_01299 1e-215 xylR GK ROK family
HDFFNFJJ_01300 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HDFFNFJJ_01301 2.7e-255 xynT G MFS/sugar transport protein
HDFFNFJJ_01302 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HDFFNFJJ_01305 6.4e-60 ynaF
HDFFNFJJ_01306 1.9e-123 ynaE S Domain of unknown function (DUF3885)
HDFFNFJJ_01307 2e-99 ynaD J Acetyltransferase (GNAT) domain
HDFFNFJJ_01308 4.9e-145 ynaC
HDFFNFJJ_01309 6.8e-80 G regulation of fungal-type cell wall biogenesis
HDFFNFJJ_01310 5.8e-39
HDFFNFJJ_01311 2.5e-32
HDFFNFJJ_01312 5e-10
HDFFNFJJ_01313 7e-261 glnA 6.3.1.2 E glutamine synthetase
HDFFNFJJ_01314 1.1e-68 glnR K transcriptional
HDFFNFJJ_01315 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HDFFNFJJ_01316 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDFFNFJJ_01317 1.7e-176 spoVK O stage V sporulation protein K
HDFFNFJJ_01318 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDFFNFJJ_01319 2e-109 ymaB
HDFFNFJJ_01320 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFFNFJJ_01321 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFFNFJJ_01322 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HDFFNFJJ_01323 4.5e-22 ymzA
HDFFNFJJ_01324 6.3e-23
HDFFNFJJ_01325 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HDFFNFJJ_01326 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDFFNFJJ_01327 2.1e-46 ymaF S YmaF family
HDFFNFJJ_01329 4.9e-51 ebrA P Small Multidrug Resistance protein
HDFFNFJJ_01330 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HDFFNFJJ_01331 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
HDFFNFJJ_01332 2.1e-126 ymaC S Replication protein
HDFFNFJJ_01333 4.6e-252 aprX O Belongs to the peptidase S8 family
HDFFNFJJ_01334 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
HDFFNFJJ_01335 1.2e-61 ymzB
HDFFNFJJ_01336 2.5e-233 cypA C Cytochrome P450
HDFFNFJJ_01337 0.0 pks13 HQ Beta-ketoacyl synthase
HDFFNFJJ_01338 0.0 dhbF IQ polyketide synthase
HDFFNFJJ_01339 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HDFFNFJJ_01340 0.0 pfaA Q Polyketide synthase of type I
HDFFNFJJ_01341 0.0 rhiB IQ polyketide synthase
HDFFNFJJ_01342 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HDFFNFJJ_01343 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HDFFNFJJ_01344 1.3e-245 pksG 2.3.3.10 I synthase
HDFFNFJJ_01345 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDFFNFJJ_01346 1.4e-37 acpK IQ Phosphopantetheine attachment site
HDFFNFJJ_01347 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HDFFNFJJ_01348 2.4e-186 pksD Q Acyl transferase domain
HDFFNFJJ_01349 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HDFFNFJJ_01350 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HDFFNFJJ_01351 4.4e-109 pksA K Transcriptional regulator
HDFFNFJJ_01352 1.2e-97 ymcC S Membrane
HDFFNFJJ_01354 2.3e-70 S Regulatory protein YrvL
HDFFNFJJ_01355 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDFFNFJJ_01356 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDFFNFJJ_01357 2.2e-88 cotE S Spore coat protein
HDFFNFJJ_01358 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HDFFNFJJ_01359 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HDFFNFJJ_01360 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HDFFNFJJ_01361 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HDFFNFJJ_01362 1.2e-36 spoVS S Stage V sporulation protein S
HDFFNFJJ_01363 1.9e-152 ymdB S protein conserved in bacteria
HDFFNFJJ_01364 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HDFFNFJJ_01365 1e-215 pbpX V Beta-lactamase
HDFFNFJJ_01366 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDFFNFJJ_01367 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HDFFNFJJ_01368 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDFFNFJJ_01369 1.9e-124 ymfM S protein conserved in bacteria
HDFFNFJJ_01370 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HDFFNFJJ_01371 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HDFFNFJJ_01372 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HDFFNFJJ_01373 1.4e-242 ymfH S zinc protease
HDFFNFJJ_01374 2.6e-236 ymfF S Peptidase M16
HDFFNFJJ_01375 1.5e-206 ymfD EGP Major facilitator Superfamily
HDFFNFJJ_01376 1.4e-133 ymfC K Transcriptional regulator
HDFFNFJJ_01377 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDFFNFJJ_01378 4.4e-32 S YlzJ-like protein
HDFFNFJJ_01379 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HDFFNFJJ_01380 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDFFNFJJ_01381 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDFFNFJJ_01382 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HDFFNFJJ_01383 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDFFNFJJ_01384 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HDFFNFJJ_01385 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HDFFNFJJ_01386 2.6e-42 ymxH S YlmC YmxH family
HDFFNFJJ_01387 4.4e-233 pepR S Belongs to the peptidase M16 family
HDFFNFJJ_01388 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HDFFNFJJ_01389 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HDFFNFJJ_01390 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDFFNFJJ_01391 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDFFNFJJ_01392 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDFFNFJJ_01393 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDFFNFJJ_01394 3e-44 ylxP S protein conserved in bacteria
HDFFNFJJ_01395 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDFFNFJJ_01396 3.1e-47 ylxQ J ribosomal protein
HDFFNFJJ_01397 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HDFFNFJJ_01398 1.1e-203 nusA K Participates in both transcription termination and antitermination
HDFFNFJJ_01399 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HDFFNFJJ_01400 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDFFNFJJ_01401 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDFFNFJJ_01402 7.7e-233 rasP M zinc metalloprotease
HDFFNFJJ_01403 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HDFFNFJJ_01404 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HDFFNFJJ_01405 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDFFNFJJ_01406 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDFFNFJJ_01407 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDFFNFJJ_01408 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDFFNFJJ_01409 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HDFFNFJJ_01410 4.3e-78 ylxL
HDFFNFJJ_01411 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDFFNFJJ_01412 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HDFFNFJJ_01413 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HDFFNFJJ_01414 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HDFFNFJJ_01415 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HDFFNFJJ_01416 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HDFFNFJJ_01417 7.5e-158 flhG D Belongs to the ParA family
HDFFNFJJ_01418 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HDFFNFJJ_01419 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HDFFNFJJ_01420 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HDFFNFJJ_01421 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HDFFNFJJ_01422 2.2e-36 fliQ N Role in flagellar biosynthesis
HDFFNFJJ_01423 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HDFFNFJJ_01424 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
HDFFNFJJ_01425 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HDFFNFJJ_01426 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HDFFNFJJ_01427 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HDFFNFJJ_01428 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HDFFNFJJ_01429 8.2e-140 flgG N Flagellar basal body rod
HDFFNFJJ_01430 1.7e-72 flgD N Flagellar basal body rod modification protein
HDFFNFJJ_01431 1.2e-221 fliK N Flagellar hook-length control protein
HDFFNFJJ_01432 7.7e-37 ylxF S MgtE intracellular N domain
HDFFNFJJ_01433 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HDFFNFJJ_01434 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HDFFNFJJ_01435 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HDFFNFJJ_01436 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HDFFNFJJ_01437 2.4e-255 fliF N The M ring may be actively involved in energy transduction
HDFFNFJJ_01438 1.9e-31 fliE N Flagellar hook-basal body
HDFFNFJJ_01439 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HDFFNFJJ_01440 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HDFFNFJJ_01441 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HDFFNFJJ_01442 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDFFNFJJ_01443 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDFFNFJJ_01444 2.5e-169 xerC L tyrosine recombinase XerC
HDFFNFJJ_01445 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDFFNFJJ_01446 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDFFNFJJ_01447 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HDFFNFJJ_01448 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HDFFNFJJ_01449 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HDFFNFJJ_01450 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HDFFNFJJ_01451 8.5e-291 ylqG
HDFFNFJJ_01452 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDFFNFJJ_01453 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDFFNFJJ_01454 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDFFNFJJ_01455 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDFFNFJJ_01456 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDFFNFJJ_01457 1.3e-61 ylqD S YlqD protein
HDFFNFJJ_01458 1.2e-36 ylqC S Belongs to the UPF0109 family
HDFFNFJJ_01459 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDFFNFJJ_01460 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDFFNFJJ_01461 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDFFNFJJ_01462 2.9e-87
HDFFNFJJ_01463 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDFFNFJJ_01464 0.0 smc D Required for chromosome condensation and partitioning
HDFFNFJJ_01465 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDFFNFJJ_01466 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDFFNFJJ_01467 6.1e-129 IQ reductase
HDFFNFJJ_01468 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HDFFNFJJ_01469 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDFFNFJJ_01470 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HDFFNFJJ_01471 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDFFNFJJ_01472 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HDFFNFJJ_01473 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HDFFNFJJ_01474 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
HDFFNFJJ_01475 5.5e-59 asp S protein conserved in bacteria
HDFFNFJJ_01476 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDFFNFJJ_01477 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDFFNFJJ_01478 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDFFNFJJ_01479 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDFFNFJJ_01480 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HDFFNFJJ_01481 2.4e-141 stp 3.1.3.16 T phosphatase
HDFFNFJJ_01482 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HDFFNFJJ_01483 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDFFNFJJ_01484 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDFFNFJJ_01485 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDFFNFJJ_01486 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDFFNFJJ_01487 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDFFNFJJ_01488 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDFFNFJJ_01489 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HDFFNFJJ_01490 1.5e-40 ylzA S Belongs to the UPF0296 family
HDFFNFJJ_01491 2.4e-156 yloC S stress-induced protein
HDFFNFJJ_01492 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HDFFNFJJ_01493 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HDFFNFJJ_01494 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HDFFNFJJ_01495 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HDFFNFJJ_01496 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HDFFNFJJ_01497 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HDFFNFJJ_01498 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HDFFNFJJ_01499 1.1e-179 cysP P phosphate transporter
HDFFNFJJ_01500 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HDFFNFJJ_01502 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDFFNFJJ_01503 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDFFNFJJ_01504 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDFFNFJJ_01505 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HDFFNFJJ_01506 0.0 carB 6.3.5.5 F Belongs to the CarB family
HDFFNFJJ_01507 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDFFNFJJ_01508 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDFFNFJJ_01509 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HDFFNFJJ_01510 9e-232 pyrP F Xanthine uracil
HDFFNFJJ_01511 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDFFNFJJ_01512 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDFFNFJJ_01513 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDFFNFJJ_01514 1.3e-63 dksA T COG1734 DnaK suppressor protein
HDFFNFJJ_01515 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDFFNFJJ_01516 2.6e-67 divIVA D Cell division initiation protein
HDFFNFJJ_01517 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HDFFNFJJ_01518 1.3e-39 yggT S membrane
HDFFNFJJ_01519 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDFFNFJJ_01520 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HDFFNFJJ_01521 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HDFFNFJJ_01522 2.4e-37 ylmC S sporulation protein
HDFFNFJJ_01523 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
HDFFNFJJ_01524 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HDFFNFJJ_01525 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDFFNFJJ_01526 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDFFNFJJ_01527 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HDFFNFJJ_01528 0.0 bpr O COG1404 Subtilisin-like serine proteases
HDFFNFJJ_01529 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDFFNFJJ_01530 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDFFNFJJ_01531 6.2e-58 sbp S small basic protein
HDFFNFJJ_01532 1e-102 ylxX S protein conserved in bacteria
HDFFNFJJ_01533 2.4e-103 ylxW S protein conserved in bacteria
HDFFNFJJ_01534 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDFFNFJJ_01535 5.3e-167 murB 1.3.1.98 M cell wall formation
HDFFNFJJ_01536 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDFFNFJJ_01537 5.7e-186 spoVE D Belongs to the SEDS family
HDFFNFJJ_01538 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDFFNFJJ_01539 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDFFNFJJ_01540 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDFFNFJJ_01541 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HDFFNFJJ_01542 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HDFFNFJJ_01543 3.7e-44 ftsL D Essential cell division protein
HDFFNFJJ_01544 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDFFNFJJ_01545 2.9e-78 mraZ K Belongs to the MraZ family
HDFFNFJJ_01546 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HDFFNFJJ_01547 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDFFNFJJ_01548 4e-89 ylbP K n-acetyltransferase
HDFFNFJJ_01549 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HDFFNFJJ_01550 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HDFFNFJJ_01551 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HDFFNFJJ_01553 2.8e-235 ylbM S Belongs to the UPF0348 family
HDFFNFJJ_01554 6.8e-187 ylbL T Belongs to the peptidase S16 family
HDFFNFJJ_01555 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HDFFNFJJ_01556 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
HDFFNFJJ_01557 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDFFNFJJ_01558 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
HDFFNFJJ_01559 7.5e-39 ylbG S UPF0298 protein
HDFFNFJJ_01560 1.8e-75 ylbF S Belongs to the UPF0342 family
HDFFNFJJ_01561 6.7e-37 ylbE S YlbE-like protein
HDFFNFJJ_01562 4.1e-63 ylbD S Putative coat protein
HDFFNFJJ_01563 3e-201 ylbC S protein with SCP PR1 domains
HDFFNFJJ_01564 2.6e-74 ylbB T COG0517 FOG CBS domain
HDFFNFJJ_01565 7e-62 ylbA S YugN-like family
HDFFNFJJ_01566 3e-167 ctaG S cytochrome c oxidase
HDFFNFJJ_01567 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HDFFNFJJ_01568 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HDFFNFJJ_01569 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HDFFNFJJ_01570 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HDFFNFJJ_01571 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HDFFNFJJ_01572 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HDFFNFJJ_01573 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDFFNFJJ_01574 4.5e-214 ftsW D Belongs to the SEDS family
HDFFNFJJ_01575 8.7e-44 ylaN S Belongs to the UPF0358 family
HDFFNFJJ_01576 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HDFFNFJJ_01577 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HDFFNFJJ_01578 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HDFFNFJJ_01579 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDFFNFJJ_01580 2.5e-32 ylaI S protein conserved in bacteria
HDFFNFJJ_01581 4.2e-47 ylaH S YlaH-like protein
HDFFNFJJ_01582 0.0 typA T GTP-binding protein TypA
HDFFNFJJ_01583 8.2e-22 S Family of unknown function (DUF5325)
HDFFNFJJ_01584 1.8e-38 ylaE
HDFFNFJJ_01585 1.2e-11 sigC S Putative zinc-finger
HDFFNFJJ_01586 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_01587 2.7e-42 ylaB
HDFFNFJJ_01588 0.0 ylaA
HDFFNFJJ_01589 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HDFFNFJJ_01590 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HDFFNFJJ_01591 6.9e-78 ykzC S Acetyltransferase (GNAT) family
HDFFNFJJ_01592 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HDFFNFJJ_01593 7.1e-26 ykzI
HDFFNFJJ_01594 7.1e-118 yktB S Belongs to the UPF0637 family
HDFFNFJJ_01595 1.6e-42 yktA S Belongs to the UPF0223 family
HDFFNFJJ_01596 3.5e-277 speA 4.1.1.19 E Arginine
HDFFNFJJ_01597 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HDFFNFJJ_01598 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDFFNFJJ_01599 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDFFNFJJ_01600 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDFFNFJJ_01601 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDFFNFJJ_01602 2e-115 recN L Putative cell-wall binding lipoprotein
HDFFNFJJ_01604 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDFFNFJJ_01605 1.4e-147 ykrA S hydrolases of the HAD superfamily
HDFFNFJJ_01606 8.2e-31 ykzG S Belongs to the UPF0356 family
HDFFNFJJ_01607 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDFFNFJJ_01608 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDFFNFJJ_01609 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HDFFNFJJ_01610 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HDFFNFJJ_01611 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HDFFNFJJ_01612 1.5e-43 abrB K of stationary sporulation gene expression
HDFFNFJJ_01613 7.7e-183 mreB D Rod-share determining protein MreBH
HDFFNFJJ_01614 1.1e-12 S Uncharacterized protein YkpC
HDFFNFJJ_01615 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HDFFNFJJ_01616 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDFFNFJJ_01617 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDFFNFJJ_01618 8.1e-39 ykoA
HDFFNFJJ_01619 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HDFFNFJJ_01620 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HDFFNFJJ_01621 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HDFFNFJJ_01622 3.1e-136 fruR K Transcriptional regulator
HDFFNFJJ_01623 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HDFFNFJJ_01624 2.5e-124 macB V ABC transporter, ATP-binding protein
HDFFNFJJ_01625 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDFFNFJJ_01626 1e-117 yknW S Yip1 domain
HDFFNFJJ_01627 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDFFNFJJ_01628 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDFFNFJJ_01629 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HDFFNFJJ_01630 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HDFFNFJJ_01631 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HDFFNFJJ_01632 8.1e-246 moeA 2.10.1.1 H molybdopterin
HDFFNFJJ_01633 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HDFFNFJJ_01634 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HDFFNFJJ_01635 2.9e-147 yknT
HDFFNFJJ_01636 5.8e-95 rok K Repressor of ComK
HDFFNFJJ_01637 4.4e-82 ykuV CO thiol-disulfide
HDFFNFJJ_01638 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HDFFNFJJ_01639 8.8e-142 ykuT M Mechanosensitive ion channel
HDFFNFJJ_01640 9e-37 ykuS S Belongs to the UPF0180 family
HDFFNFJJ_01641 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDFFNFJJ_01642 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDFFNFJJ_01643 3.2e-80 fld C Flavodoxin
HDFFNFJJ_01644 3.2e-177 ykuO
HDFFNFJJ_01645 5.7e-88 fld C Flavodoxin domain
HDFFNFJJ_01646 3.5e-168 ccpC K Transcriptional regulator
HDFFNFJJ_01647 1.6e-76 ykuL S CBS domain
HDFFNFJJ_01648 3.9e-27 ykzF S Antirepressor AbbA
HDFFNFJJ_01649 4.4e-94 ykuK S Ribonuclease H-like
HDFFNFJJ_01650 3.9e-37 ykuJ S protein conserved in bacteria
HDFFNFJJ_01651 5.2e-234 ykuI T Diguanylate phosphodiesterase
HDFFNFJJ_01653 1.7e-93 M Peptidoglycan-binding domain 1 protein
HDFFNFJJ_01654 0.0 3.2.1.132 M Putative peptidoglycan binding domain
HDFFNFJJ_01655 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_01656 9.4e-166 ykuE S Metallophosphoesterase
HDFFNFJJ_01657 4.6e-88 ykuD S protein conserved in bacteria
HDFFNFJJ_01658 1.6e-238 ykuC EGP Major facilitator Superfamily
HDFFNFJJ_01659 1.7e-84 ykyB S YkyB-like protein
HDFFNFJJ_01660 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HDFFNFJJ_01661 2.2e-15
HDFFNFJJ_01662 8e-224 patA 2.6.1.1 E Aminotransferase
HDFFNFJJ_01663 0.0 pilS 2.7.13.3 T Histidine kinase
HDFFNFJJ_01664 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HDFFNFJJ_01665 8e-124 ykwD J protein with SCP PR1 domains
HDFFNFJJ_01666 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HDFFNFJJ_01667 2e-264 mcpC NT chemotaxis protein
HDFFNFJJ_01668 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDFFNFJJ_01669 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
HDFFNFJJ_01670 7.2e-39 splA S Transcriptional regulator
HDFFNFJJ_01671 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDFFNFJJ_01672 2.1e-39 ptsH G phosphocarrier protein HPr
HDFFNFJJ_01673 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFFNFJJ_01674 4.5e-128 glcT K antiterminator
HDFFNFJJ_01676 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
HDFFNFJJ_01678 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HDFFNFJJ_01679 3.8e-09
HDFFNFJJ_01680 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HDFFNFJJ_01681 4.9e-90 stoA CO thiol-disulfide
HDFFNFJJ_01682 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDFFNFJJ_01683 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HDFFNFJJ_01684 2.8e-28
HDFFNFJJ_01685 6e-25 ykvS S protein conserved in bacteria
HDFFNFJJ_01686 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HDFFNFJJ_01687 8.5e-133 G Glycosyl hydrolases family 18
HDFFNFJJ_01688 1.2e-35 3.5.1.104 M LysM domain
HDFFNFJJ_01689 1.3e-234 ykvP 3.5.1.28 M Glycosyl transferases group 1
HDFFNFJJ_01690 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HDFFNFJJ_01691 2e-61 ykvN K Transcriptional regulator
HDFFNFJJ_01692 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HDFFNFJJ_01693 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HDFFNFJJ_01694 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HDFFNFJJ_01695 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HDFFNFJJ_01696 8.7e-182 ykvI S membrane
HDFFNFJJ_01697 0.0 clpE O Belongs to the ClpA ClpB family
HDFFNFJJ_01698 2.7e-138 motA N flagellar motor
HDFFNFJJ_01699 2.5e-125 motB N Flagellar motor protein
HDFFNFJJ_01700 1.3e-75 ykvE K transcriptional
HDFFNFJJ_01701 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HDFFNFJJ_01702 1.4e-64 eag
HDFFNFJJ_01703 6.4e-09 S Spo0E like sporulation regulatory protein
HDFFNFJJ_01704 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HDFFNFJJ_01705 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HDFFNFJJ_01706 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HDFFNFJJ_01707 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HDFFNFJJ_01708 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HDFFNFJJ_01709 8e-232 mtnE 2.6.1.83 E Aminotransferase
HDFFNFJJ_01710 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HDFFNFJJ_01711 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HDFFNFJJ_01712 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HDFFNFJJ_01714 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDFFNFJJ_01715 0.0 kinE 2.7.13.3 T Histidine kinase
HDFFNFJJ_01716 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HDFFNFJJ_01717 4.5e-22 ykzE
HDFFNFJJ_01718 1.2e-10 ydfR S Protein of unknown function (DUF421)
HDFFNFJJ_01719 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HDFFNFJJ_01720 7e-156 htpX O Belongs to the peptidase M48B family
HDFFNFJJ_01721 1.5e-124 ykrK S Domain of unknown function (DUF1836)
HDFFNFJJ_01722 1.9e-26 sspD S small acid-soluble spore protein
HDFFNFJJ_01723 8.2e-117 rsgI S Anti-sigma factor N-terminus
HDFFNFJJ_01724 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDFFNFJJ_01725 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HDFFNFJJ_01726 1.4e-116 ykoX S membrane-associated protein
HDFFNFJJ_01727 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HDFFNFJJ_01728 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HDFFNFJJ_01729 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HDFFNFJJ_01730 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDFFNFJJ_01731 0.0 ykoS
HDFFNFJJ_01732 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HDFFNFJJ_01733 3.7e-99 ykoP G polysaccharide deacetylase
HDFFNFJJ_01734 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HDFFNFJJ_01735 1.3e-81 mhqR K transcriptional
HDFFNFJJ_01736 6.9e-26 ykoL
HDFFNFJJ_01737 5.9e-18
HDFFNFJJ_01738 1.4e-53 tnrA K transcriptional
HDFFNFJJ_01739 2.2e-222 mgtE P Acts as a magnesium transporter
HDFFNFJJ_01742 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
HDFFNFJJ_01743 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
HDFFNFJJ_01744 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
HDFFNFJJ_01745 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_01746 7.9e-111 ykoF S YKOF-related Family
HDFFNFJJ_01747 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HDFFNFJJ_01748 4.6e-311 P ABC transporter, ATP-binding protein
HDFFNFJJ_01749 1.8e-136 ykoC P Cobalt transport protein
HDFFNFJJ_01750 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDFFNFJJ_01751 1.7e-176 isp O Belongs to the peptidase S8 family
HDFFNFJJ_01752 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDFFNFJJ_01753 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HDFFNFJJ_01755 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HDFFNFJJ_01756 3.9e-75 ohrR K COG1846 Transcriptional regulators
HDFFNFJJ_01757 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HDFFNFJJ_01758 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDFFNFJJ_01759 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDFFNFJJ_01760 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HDFFNFJJ_01761 1.1e-50 ykkD P Multidrug resistance protein
HDFFNFJJ_01762 3.5e-55 ykkC P Multidrug resistance protein
HDFFNFJJ_01763 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HDFFNFJJ_01764 1e-98 ykkA S Protein of unknown function (DUF664)
HDFFNFJJ_01765 5.4e-130 ykjA S Protein of unknown function (DUF421)
HDFFNFJJ_01766 1e-07
HDFFNFJJ_01767 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HDFFNFJJ_01768 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HDFFNFJJ_01769 5.3e-161 ykgA E Amidinotransferase
HDFFNFJJ_01770 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HDFFNFJJ_01771 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
HDFFNFJJ_01772 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HDFFNFJJ_01773 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HDFFNFJJ_01774 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HDFFNFJJ_01776 0.0 dppE E ABC transporter substrate-binding protein
HDFFNFJJ_01777 3.4e-191 dppD P Belongs to the ABC transporter superfamily
HDFFNFJJ_01778 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDFFNFJJ_01779 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDFFNFJJ_01780 7.9e-154 dppA E D-aminopeptidase
HDFFNFJJ_01781 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HDFFNFJJ_01782 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDFFNFJJ_01784 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDFFNFJJ_01785 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDFFNFJJ_01787 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HDFFNFJJ_01788 9.4e-242 steT E amino acid
HDFFNFJJ_01789 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HDFFNFJJ_01790 5.8e-175 pit P phosphate transporter
HDFFNFJJ_01791 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HDFFNFJJ_01792 6.7e-23 spoIISB S Stage II sporulation protein SB
HDFFNFJJ_01793 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDFFNFJJ_01794 9.3e-40 xhlB S SPP1 phage holin
HDFFNFJJ_01795 2.8e-39 xhlA S Haemolysin XhlA
HDFFNFJJ_01796 1.2e-154 xepA
HDFFNFJJ_01797 1.7e-23 xkdX
HDFFNFJJ_01798 2.6e-55 xkdW S XkdW protein
HDFFNFJJ_01799 0.0
HDFFNFJJ_01800 6.7e-41
HDFFNFJJ_01801 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HDFFNFJJ_01802 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HDFFNFJJ_01803 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HDFFNFJJ_01804 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HDFFNFJJ_01805 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HDFFNFJJ_01806 3.7e-122 xkdP S Lysin motif
HDFFNFJJ_01807 0.0 xkdO L Transglycosylase SLT domain
HDFFNFJJ_01808 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HDFFNFJJ_01809 6.1e-76 xkdM S Phage tail tube protein
HDFFNFJJ_01810 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HDFFNFJJ_01811 1.9e-77 xkdJ
HDFFNFJJ_01812 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HDFFNFJJ_01813 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HDFFNFJJ_01814 5.5e-65 yqbG S Protein of unknown function (DUF3199)
HDFFNFJJ_01815 5.8e-169 xkdG S Phage capsid family
HDFFNFJJ_01816 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HDFFNFJJ_01817 5.4e-286 yqbA S portal protein
HDFFNFJJ_01818 9.6e-255 xtmB S phage terminase, large subunit
HDFFNFJJ_01819 4.8e-140 xtmA L phage terminase small subunit
HDFFNFJJ_01820 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HDFFNFJJ_01821 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HDFFNFJJ_01824 6.4e-119 xkdC L Bacterial dnaA protein
HDFFNFJJ_01825 5.9e-157 xkdB K sequence-specific DNA binding
HDFFNFJJ_01827 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HDFFNFJJ_01828 1.6e-111 xkdA E IrrE N-terminal-like domain
HDFFNFJJ_01829 4.4e-160 ydbD P Catalase
HDFFNFJJ_01830 4.2e-112 yjqB S Pfam:DUF867
HDFFNFJJ_01831 2.1e-61 yjqA S Bacterial PH domain
HDFFNFJJ_01832 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HDFFNFJJ_01833 6.3e-41 S YCII-related domain
HDFFNFJJ_01835 2.1e-213 S response regulator aspartate phosphatase
HDFFNFJJ_01836 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HDFFNFJJ_01837 3.3e-80 yjoA S DinB family
HDFFNFJJ_01838 4.3e-130 MA20_18170 S membrane transporter protein
HDFFNFJJ_01839 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HDFFNFJJ_01840 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HDFFNFJJ_01841 2.3e-184 exuR K transcriptional
HDFFNFJJ_01842 3.7e-227 exuT G Sugar (and other) transporter
HDFFNFJJ_01843 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_01844 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HDFFNFJJ_01845 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HDFFNFJJ_01846 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HDFFNFJJ_01847 5.8e-250 yjmB G symporter YjmB
HDFFNFJJ_01848 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
HDFFNFJJ_01849 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HDFFNFJJ_01850 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HDFFNFJJ_01851 2.8e-93 yjlB S Cupin domain
HDFFNFJJ_01852 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
HDFFNFJJ_01853 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HDFFNFJJ_01854 1.9e-122 ybbM S transport system, permease component
HDFFNFJJ_01855 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HDFFNFJJ_01856 8.2e-30
HDFFNFJJ_01857 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HDFFNFJJ_01858 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HDFFNFJJ_01860 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HDFFNFJJ_01861 8.7e-07 S Domain of unknown function (DUF4352)
HDFFNFJJ_01862 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HDFFNFJJ_01863 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HDFFNFJJ_01864 8.9e-104 yjgB S Domain of unknown function (DUF4309)
HDFFNFJJ_01865 1.2e-45 T PhoQ Sensor
HDFFNFJJ_01866 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
HDFFNFJJ_01867 3.6e-21 yjfB S Putative motility protein
HDFFNFJJ_01868 5.5e-83 S Protein of unknown function (DUF2690)
HDFFNFJJ_01869 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HDFFNFJJ_01871 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HDFFNFJJ_01872 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HDFFNFJJ_01873 4.2e-29 S Domain of unknown function (DUF4177)
HDFFNFJJ_01874 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDFFNFJJ_01876 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HDFFNFJJ_01877 4.8e-51 yjdF S Protein of unknown function (DUF2992)
HDFFNFJJ_01878 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDFFNFJJ_01879 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HDFFNFJJ_01880 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HDFFNFJJ_01882 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
HDFFNFJJ_01883 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
HDFFNFJJ_01884 1.1e-92 yqaS L DNA packaging
HDFFNFJJ_01885 4.1e-49 S YjcQ protein
HDFFNFJJ_01886 1.6e-72 yjcP
HDFFNFJJ_01887 8.5e-81 L Transposase
HDFFNFJJ_01890 2.6e-44 yjcN
HDFFNFJJ_01891 2.1e-190 S Putative amidase domain
HDFFNFJJ_01894 1.1e-212 yjcL S Protein of unknown function (DUF819)
HDFFNFJJ_01895 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
HDFFNFJJ_01896 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDFFNFJJ_01897 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDFFNFJJ_01898 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
HDFFNFJJ_01899 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HDFFNFJJ_01900 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDFFNFJJ_01901 1.7e-38
HDFFNFJJ_01902 0.0 yjcD 3.6.4.12 L DNA helicase
HDFFNFJJ_01903 2.9e-38 spoVIF S Stage VI sporulation protein F
HDFFNFJJ_01906 8.7e-57 yjcA S Protein of unknown function (DUF1360)
HDFFNFJJ_01907 2.3e-55 cotV S Spore Coat Protein X and V domain
HDFFNFJJ_01908 3e-32 cotW
HDFFNFJJ_01909 6.4e-77 cotX S Spore Coat Protein X and V domain
HDFFNFJJ_01910 3.4e-96 cotY S Spore coat protein Z
HDFFNFJJ_01911 5.2e-83 cotZ S Spore coat protein
HDFFNFJJ_01912 5.9e-54 yjbX S Spore coat protein
HDFFNFJJ_01913 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HDFFNFJJ_01914 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDFFNFJJ_01915 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HDFFNFJJ_01916 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HDFFNFJJ_01917 3e-30 thiS H thiamine diphosphate biosynthetic process
HDFFNFJJ_01918 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
HDFFNFJJ_01919 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HDFFNFJJ_01920 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HDFFNFJJ_01921 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDFFNFJJ_01922 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HDFFNFJJ_01923 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDFFNFJJ_01924 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDFFNFJJ_01925 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HDFFNFJJ_01926 7.1e-62 yjbL S Belongs to the UPF0738 family
HDFFNFJJ_01927 2.4e-101 yjbK S protein conserved in bacteria
HDFFNFJJ_01928 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HDFFNFJJ_01929 3.7e-72 yjbI S Bacterial-like globin
HDFFNFJJ_01930 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HDFFNFJJ_01932 1.8e-20
HDFFNFJJ_01933 0.0 pepF E oligoendopeptidase F
HDFFNFJJ_01934 2.3e-223 yjbF S Competence protein
HDFFNFJJ_01935 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HDFFNFJJ_01936 6e-112 yjbE P Integral membrane protein TerC family
HDFFNFJJ_01937 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDFFNFJJ_01938 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDFFNFJJ_01939 8.6e-196 yjbB EGP Major Facilitator Superfamily
HDFFNFJJ_01940 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HDFFNFJJ_01941 3e-198 oppD P Belongs to the ABC transporter superfamily
HDFFNFJJ_01942 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDFFNFJJ_01943 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDFFNFJJ_01944 0.0 oppA E ABC transporter substrate-binding protein
HDFFNFJJ_01945 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HDFFNFJJ_01946 5e-147 yjbA S Belongs to the UPF0736 family
HDFFNFJJ_01947 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDFFNFJJ_01948 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDFFNFJJ_01949 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HDFFNFJJ_01950 6.5e-187 appF E Belongs to the ABC transporter superfamily
HDFFNFJJ_01951 1.8e-184 appD P Belongs to the ABC transporter superfamily
HDFFNFJJ_01952 7.8e-151 yjaZ O Zn-dependent protease
HDFFNFJJ_01953 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDFFNFJJ_01954 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDFFNFJJ_01955 2.7e-22 yjzB
HDFFNFJJ_01956 7.3e-26 comZ S ComZ
HDFFNFJJ_01957 1.1e-183 med S Transcriptional activator protein med
HDFFNFJJ_01958 7.3e-103 yjaV
HDFFNFJJ_01959 6.2e-142 yjaU I carboxylic ester hydrolase activity
HDFFNFJJ_01960 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HDFFNFJJ_01961 9.5e-28 yjzC S YjzC-like protein
HDFFNFJJ_01962 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDFFNFJJ_01963 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HDFFNFJJ_01964 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDFFNFJJ_01965 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HDFFNFJJ_01966 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HDFFNFJJ_01967 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDFFNFJJ_01968 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDFFNFJJ_01969 1.7e-88 norB G Major Facilitator Superfamily
HDFFNFJJ_01970 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
HDFFNFJJ_01971 1.5e-22 pilT S Proteolipid membrane potential modulator
HDFFNFJJ_01972 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HDFFNFJJ_01973 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HDFFNFJJ_01974 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HDFFNFJJ_01975 1.2e-17 S Protein of unknown function (DUF3813)
HDFFNFJJ_01976 1.9e-72 ipi S Intracellular proteinase inhibitor
HDFFNFJJ_01977 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HDFFNFJJ_01978 1.5e-155 yitS S protein conserved in bacteria
HDFFNFJJ_01979 2.2e-311 nprB 3.4.24.28 E Peptidase M4
HDFFNFJJ_01980 1.4e-44 yitR S Domain of unknown function (DUF3784)
HDFFNFJJ_01981 2e-95
HDFFNFJJ_01982 1.5e-58 K Transcriptional regulator PadR-like family
HDFFNFJJ_01983 1.5e-97 S Sporulation delaying protein SdpA
HDFFNFJJ_01984 4e-170
HDFFNFJJ_01985 8.5e-94
HDFFNFJJ_01986 4e-161 cvfB S protein conserved in bacteria
HDFFNFJJ_01987 8.6e-55 yajQ S Belongs to the UPF0234 family
HDFFNFJJ_01988 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HDFFNFJJ_01989 2e-82 yjcF S Acetyltransferase (GNAT) domain
HDFFNFJJ_01990 1.8e-161 yitH K Acetyltransferase (GNAT) domain
HDFFNFJJ_01991 4e-229 yitG EGP Major facilitator Superfamily
HDFFNFJJ_01992 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HDFFNFJJ_01993 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDFFNFJJ_01994 1.9e-141 yitD 4.4.1.19 S synthase
HDFFNFJJ_01995 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
HDFFNFJJ_01996 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HDFFNFJJ_01997 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HDFFNFJJ_01998 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HDFFNFJJ_01999 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDFFNFJJ_02000 4e-36 mcbG S Pentapeptide repeats (9 copies)
HDFFNFJJ_02001 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDFFNFJJ_02002 6.4e-108 argO S Lysine exporter protein LysE YggA
HDFFNFJJ_02003 1.3e-93 yisT S DinB family
HDFFNFJJ_02004 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HDFFNFJJ_02005 2.4e-184 purR K helix_turn _helix lactose operon repressor
HDFFNFJJ_02006 1.2e-160 yisR K Transcriptional regulator
HDFFNFJJ_02007 4e-243 yisQ V Mate efflux family protein
HDFFNFJJ_02008 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HDFFNFJJ_02009 2.1e-88 yizA S Damage-inducible protein DinB
HDFFNFJJ_02010 0.0 asnO 6.3.5.4 E Asparagine synthase
HDFFNFJJ_02011 7.2e-106 yisN S Protein of unknown function (DUF2777)
HDFFNFJJ_02012 0.0 wprA O Belongs to the peptidase S8 family
HDFFNFJJ_02013 3e-57 yisL S UPF0344 protein
HDFFNFJJ_02014 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HDFFNFJJ_02015 1.7e-176 cotH M Spore Coat
HDFFNFJJ_02016 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HDFFNFJJ_02017 1.9e-33 gerPA S Spore germination protein
HDFFNFJJ_02018 4e-34 gerPB S cell differentiation
HDFFNFJJ_02019 1.8e-54 gerPC S Spore germination protein
HDFFNFJJ_02020 6.3e-24 gerPD S Spore germination protein
HDFFNFJJ_02021 3e-66 gerPE S Spore germination protein GerPE
HDFFNFJJ_02022 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HDFFNFJJ_02023 6e-51 yisB V COG1403 Restriction endonuclease
HDFFNFJJ_02024 0.0 sbcC L COG0419 ATPase involved in DNA repair
HDFFNFJJ_02025 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDFFNFJJ_02026 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDFFNFJJ_02027 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HDFFNFJJ_02028 2.2e-78 yhjR S Rubrerythrin
HDFFNFJJ_02029 2e-36 yhjQ C COG1145 Ferredoxin
HDFFNFJJ_02030 0.0 S Sugar transport-related sRNA regulator N-term
HDFFNFJJ_02031 3.1e-215 EGP Transmembrane secretion effector
HDFFNFJJ_02032 3.8e-202 abrB S membrane
HDFFNFJJ_02033 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
HDFFNFJJ_02034 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HDFFNFJJ_02035 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HDFFNFJJ_02036 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HDFFNFJJ_02037 6.9e-215 glcP G Major Facilitator Superfamily
HDFFNFJJ_02038 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_02039 4.2e-286 yhjG CH FAD binding domain
HDFFNFJJ_02040 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HDFFNFJJ_02041 9.1e-110 yhjE S SNARE associated Golgi protein
HDFFNFJJ_02042 5e-60 yhjD
HDFFNFJJ_02043 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HDFFNFJJ_02044 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDFFNFJJ_02045 7.8e-42 yhjA S Excalibur calcium-binding domain
HDFFNFJJ_02046 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HDFFNFJJ_02047 4.2e-109 comK K Competence transcription factor
HDFFNFJJ_02048 1.3e-32 yhzC S IDEAL
HDFFNFJJ_02049 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_02050 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HDFFNFJJ_02051 1.7e-182 hemAT NT chemotaxis protein
HDFFNFJJ_02052 5e-91 bioY S BioY family
HDFFNFJJ_02053 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HDFFNFJJ_02054 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
HDFFNFJJ_02055 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HDFFNFJJ_02056 4.3e-159 yfmC M Periplasmic binding protein
HDFFNFJJ_02057 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HDFFNFJJ_02058 9.2e-80 VY92_01935 K acetyltransferase
HDFFNFJJ_02059 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HDFFNFJJ_02060 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
HDFFNFJJ_02061 1.9e-65 yhfM
HDFFNFJJ_02062 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HDFFNFJJ_02063 2.6e-112 yhfK GM NmrA-like family
HDFFNFJJ_02064 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
HDFFNFJJ_02065 2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HDFFNFJJ_02066 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDFFNFJJ_02067 1.7e-72 3.4.13.21 S ASCH
HDFFNFJJ_02068 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HDFFNFJJ_02069 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
HDFFNFJJ_02070 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDFFNFJJ_02071 1e-238 yhgE S YhgE Pip N-terminal domain protein
HDFFNFJJ_02072 1.4e-101 yhgD K Transcriptional regulator
HDFFNFJJ_02073 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HDFFNFJJ_02074 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HDFFNFJJ_02075 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HDFFNFJJ_02076 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDFFNFJJ_02077 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HDFFNFJJ_02078 7.5e-17 1.15.1.2 C Rubrerythrin
HDFFNFJJ_02079 4.2e-248 yhfA C membrane
HDFFNFJJ_02080 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HDFFNFJJ_02081 4.8e-115 ecsC S EcsC protein family
HDFFNFJJ_02082 1.8e-215 ecsB U ABC transporter
HDFFNFJJ_02083 4.6e-137 ecsA V transporter (ATP-binding protein)
HDFFNFJJ_02084 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HDFFNFJJ_02085 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDFFNFJJ_02086 3.6e-80 trpP S Tryptophan transporter TrpP
HDFFNFJJ_02087 7e-39 yhaH S YtxH-like protein
HDFFNFJJ_02088 1e-113 hpr K Negative regulator of protease production and sporulation
HDFFNFJJ_02089 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HDFFNFJJ_02090 8.7e-90 yhaK S Putative zincin peptidase
HDFFNFJJ_02091 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDFFNFJJ_02092 1.6e-21 yhaL S Sporulation protein YhaL
HDFFNFJJ_02093 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HDFFNFJJ_02094 0.0 yhaN L AAA domain
HDFFNFJJ_02095 3.6e-227 yhaO L DNA repair exonuclease
HDFFNFJJ_02096 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HDFFNFJJ_02097 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HDFFNFJJ_02098 1.1e-26 S YhzD-like protein
HDFFNFJJ_02099 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HDFFNFJJ_02101 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HDFFNFJJ_02102 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HDFFNFJJ_02103 7.1e-294 hemZ H coproporphyrinogen III oxidase
HDFFNFJJ_02104 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HDFFNFJJ_02105 3.1e-206 yhaZ L DNA alkylation repair enzyme
HDFFNFJJ_02106 9.5e-48 yheA S Belongs to the UPF0342 family
HDFFNFJJ_02107 6.7e-204 yheB S Belongs to the UPF0754 family
HDFFNFJJ_02108 4.3e-216 yheC HJ YheC/D like ATP-grasp
HDFFNFJJ_02109 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HDFFNFJJ_02110 1.3e-36 yheE S Family of unknown function (DUF5342)
HDFFNFJJ_02111 6.3e-28 sspB S spore protein
HDFFNFJJ_02112 3.7e-111 yheG GM NAD(P)H-binding
HDFFNFJJ_02113 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDFFNFJJ_02114 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDFFNFJJ_02115 3.4e-84 nhaX T Belongs to the universal stress protein A family
HDFFNFJJ_02116 2.2e-233 nhaC C Na H antiporter
HDFFNFJJ_02117 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HDFFNFJJ_02118 1.7e-151 yheN G deacetylase
HDFFNFJJ_02119 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HDFFNFJJ_02120 6.6e-204 yhdY M Mechanosensitive ion channel
HDFFNFJJ_02122 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDFFNFJJ_02123 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDFFNFJJ_02124 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDFFNFJJ_02125 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HDFFNFJJ_02126 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
HDFFNFJJ_02127 4.1e-74 cueR K transcriptional
HDFFNFJJ_02128 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HDFFNFJJ_02129 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HDFFNFJJ_02130 1.5e-191 yhdN C Aldo keto reductase
HDFFNFJJ_02131 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_02132 6.6e-201 yhdL S Sigma factor regulator N-terminal
HDFFNFJJ_02133 8.1e-45 yhdK S Sigma-M inhibitor protein
HDFFNFJJ_02134 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDFFNFJJ_02135 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDFFNFJJ_02136 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HDFFNFJJ_02137 3.4e-250 yhdG E amino acid
HDFFNFJJ_02138 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_02139 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HDFFNFJJ_02140 3.8e-162 citR K Transcriptional regulator
HDFFNFJJ_02141 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HDFFNFJJ_02142 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HDFFNFJJ_02143 2.1e-276 ycgB S Stage V sporulation protein R
HDFFNFJJ_02144 8.7e-239 ygxB M Conserved TM helix
HDFFNFJJ_02145 3.5e-76 nsrR K Transcriptional regulator
HDFFNFJJ_02146 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HDFFNFJJ_02147 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HDFFNFJJ_02148 1.2e-38 yhdB S YhdB-like protein
HDFFNFJJ_02149 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HDFFNFJJ_02150 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDFFNFJJ_02151 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
HDFFNFJJ_02152 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HDFFNFJJ_02153 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HDFFNFJJ_02154 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDFFNFJJ_02155 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HDFFNFJJ_02156 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HDFFNFJJ_02157 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDFFNFJJ_02158 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HDFFNFJJ_02159 4.6e-120 yhcW 5.4.2.6 S hydrolase
HDFFNFJJ_02160 9.9e-68 yhcV S COG0517 FOG CBS domain
HDFFNFJJ_02161 9.3e-68 yhcU S Family of unknown function (DUF5365)
HDFFNFJJ_02162 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDFFNFJJ_02163 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HDFFNFJJ_02164 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HDFFNFJJ_02165 5.2e-100 yhcQ M Spore coat protein
HDFFNFJJ_02166 2.5e-167 yhcP
HDFFNFJJ_02167 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDFFNFJJ_02168 3.7e-44 yhcM
HDFFNFJJ_02169 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDFFNFJJ_02170 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HDFFNFJJ_02171 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
HDFFNFJJ_02172 1e-30 cspB K Cold-shock protein
HDFFNFJJ_02173 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HDFFNFJJ_02174 2.6e-166 yhcH V ABC transporter, ATP-binding protein
HDFFNFJJ_02175 1.6e-123 yhcG V ABC transporter, ATP-binding protein
HDFFNFJJ_02176 6.6e-60 yhcF K Transcriptional regulator
HDFFNFJJ_02177 7.8e-55
HDFFNFJJ_02178 2.8e-37 yhcC
HDFFNFJJ_02179 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HDFFNFJJ_02180 3.1e-271 yhcA EGP Major facilitator Superfamily
HDFFNFJJ_02181 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HDFFNFJJ_02182 2.2e-76 yhbI K DNA-binding transcription factor activity
HDFFNFJJ_02183 2.5e-225 yhbH S Belongs to the UPF0229 family
HDFFNFJJ_02184 0.0 prkA T Ser protein kinase
HDFFNFJJ_02185 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HDFFNFJJ_02186 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HDFFNFJJ_02187 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HDFFNFJJ_02188 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDFFNFJJ_02189 4.4e-177 yhbB S Putative amidase domain
HDFFNFJJ_02190 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HDFFNFJJ_02191 7.9e-114 yhzB S B3/4 domain
HDFFNFJJ_02193 4.4e-29 K Transcriptional regulator
HDFFNFJJ_02194 4.1e-78 ygaO
HDFFNFJJ_02195 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDFFNFJJ_02197 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HDFFNFJJ_02198 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HDFFNFJJ_02199 1.7e-171 ssuA M Sulfonate ABC transporter
HDFFNFJJ_02200 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HDFFNFJJ_02201 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HDFFNFJJ_02203 1.9e-266 ygaK C Berberine and berberine like
HDFFNFJJ_02204 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HDFFNFJJ_02205 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HDFFNFJJ_02206 3e-27
HDFFNFJJ_02207 2.7e-143 spo0M S COG4326 Sporulation control protein
HDFFNFJJ_02211 2e-08
HDFFNFJJ_02219 7.8e-08
HDFFNFJJ_02226 9.3e-116
HDFFNFJJ_02227 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HDFFNFJJ_02228 6.2e-145 S Phage tail protein
HDFFNFJJ_02229 0.0 S Pfam Transposase IS66
HDFFNFJJ_02230 6.4e-115
HDFFNFJJ_02231 0.0 G Exopolysaccharide biosynthesis protein
HDFFNFJJ_02232 6.5e-164
HDFFNFJJ_02234 1.6e-186 3.5.1.28 M Ami_2
HDFFNFJJ_02235 4.4e-32 bhlA S BhlA holin family
HDFFNFJJ_02236 5.5e-40 S SPP1 phage holin
HDFFNFJJ_02237 3.4e-74 O protein disulfide oxidoreductase activity
HDFFNFJJ_02238 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDFFNFJJ_02239 1.2e-70 CO cell redox homeostasis
HDFFNFJJ_02240 0.0 V Peptidase C39 family
HDFFNFJJ_02243 1.9e-239 S impB/mucB/samB family C-terminal domain
HDFFNFJJ_02244 5.8e-55 S YolD-like protein
HDFFNFJJ_02245 2.5e-42
HDFFNFJJ_02247 6.8e-09 S Domain of unknown function (DUF4879)
HDFFNFJJ_02249 2.8e-99 J Acetyltransferase (GNAT) domain
HDFFNFJJ_02250 3.2e-109 yokK S SMI1 / KNR4 family
HDFFNFJJ_02251 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
HDFFNFJJ_02252 1.2e-302 UW nuclease activity
HDFFNFJJ_02253 6.7e-92 yokH G SMI1 / KNR4 family
HDFFNFJJ_02254 4.1e-203
HDFFNFJJ_02255 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
HDFFNFJJ_02256 1.1e-83 S Bacterial PH domain
HDFFNFJJ_02257 8.4e-156 aacC 2.3.1.81 V aminoglycoside
HDFFNFJJ_02260 8.9e-95
HDFFNFJJ_02261 1.6e-107
HDFFNFJJ_02262 2.7e-307 yokA L Recombinase
HDFFNFJJ_02263 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
HDFFNFJJ_02264 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HDFFNFJJ_02265 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDFFNFJJ_02266 1.6e-70 ypoP K transcriptional
HDFFNFJJ_02267 2.6e-223 mepA V MATE efflux family protein
HDFFNFJJ_02268 5.5e-29 ypmT S Uncharacterized ympT
HDFFNFJJ_02269 5e-99 ypmS S protein conserved in bacteria
HDFFNFJJ_02270 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HDFFNFJJ_02271 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HDFFNFJJ_02272 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HDFFNFJJ_02273 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HDFFNFJJ_02274 1.6e-185 pspF K Transcriptional regulator
HDFFNFJJ_02275 4.2e-110 hlyIII S protein, Hemolysin III
HDFFNFJJ_02276 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HDFFNFJJ_02277 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDFFNFJJ_02278 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDFFNFJJ_02279 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HDFFNFJJ_02280 7.8e-114 ypjP S YpjP-like protein
HDFFNFJJ_02281 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HDFFNFJJ_02282 1.7e-75 yphP S Belongs to the UPF0403 family
HDFFNFJJ_02283 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HDFFNFJJ_02284 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HDFFNFJJ_02285 3.1e-110 ypgQ S phosphohydrolase
HDFFNFJJ_02286 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HDFFNFJJ_02287 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HDFFNFJJ_02288 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HDFFNFJJ_02289 7.9e-31 cspD K Cold-shock protein
HDFFNFJJ_02290 3.8e-16 degR
HDFFNFJJ_02291 8.1e-31 S Protein of unknown function (DUF2564)
HDFFNFJJ_02292 3e-29 ypeQ S Zinc-finger
HDFFNFJJ_02293 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HDFFNFJJ_02294 1.1e-121 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HDFFNFJJ_02295 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HDFFNFJJ_02297 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HDFFNFJJ_02298 2e-07
HDFFNFJJ_02299 1e-38 ypbS S Protein of unknown function (DUF2533)
HDFFNFJJ_02300 0.0 ypbR S Dynamin family
HDFFNFJJ_02301 5.1e-87 ypbQ S protein conserved in bacteria
HDFFNFJJ_02302 4.4e-208 bcsA Q Naringenin-chalcone synthase
HDFFNFJJ_02303 1.6e-228 pbuX F xanthine
HDFFNFJJ_02304 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDFFNFJJ_02305 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HDFFNFJJ_02306 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HDFFNFJJ_02307 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HDFFNFJJ_02308 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HDFFNFJJ_02309 3.9e-187 ptxS K transcriptional
HDFFNFJJ_02310 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HDFFNFJJ_02311 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_02312 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HDFFNFJJ_02314 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDFFNFJJ_02315 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDFFNFJJ_02316 3.3e-92 ypsA S Belongs to the UPF0398 family
HDFFNFJJ_02317 1.3e-237 yprB L RNase_H superfamily
HDFFNFJJ_02318 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HDFFNFJJ_02319 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HDFFNFJJ_02320 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HDFFNFJJ_02321 1.2e-48 yppG S YppG-like protein
HDFFNFJJ_02323 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HDFFNFJJ_02326 2.6e-188 yppC S Protein of unknown function (DUF2515)
HDFFNFJJ_02327 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDFFNFJJ_02328 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HDFFNFJJ_02329 4.7e-93 ypoC
HDFFNFJJ_02330 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDFFNFJJ_02331 5.7e-129 dnaD L DNA replication protein DnaD
HDFFNFJJ_02332 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HDFFNFJJ_02333 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HDFFNFJJ_02334 3.4e-80 ypmB S protein conserved in bacteria
HDFFNFJJ_02335 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HDFFNFJJ_02336 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDFFNFJJ_02337 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HDFFNFJJ_02338 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HDFFNFJJ_02339 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HDFFNFJJ_02340 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDFFNFJJ_02341 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDFFNFJJ_02342 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HDFFNFJJ_02343 6.9e-130 bshB1 S proteins, LmbE homologs
HDFFNFJJ_02344 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HDFFNFJJ_02345 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDFFNFJJ_02346 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HDFFNFJJ_02347 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HDFFNFJJ_02348 6.1e-143 ypjB S sporulation protein
HDFFNFJJ_02349 4.4e-98 ypjA S membrane
HDFFNFJJ_02350 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HDFFNFJJ_02351 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HDFFNFJJ_02352 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HDFFNFJJ_02353 8.5e-78 ypiF S Protein of unknown function (DUF2487)
HDFFNFJJ_02354 2.8e-99 ypiB S Belongs to the UPF0302 family
HDFFNFJJ_02355 4.1e-234 S COG0457 FOG TPR repeat
HDFFNFJJ_02356 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDFFNFJJ_02357 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HDFFNFJJ_02358 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDFFNFJJ_02359 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDFFNFJJ_02360 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDFFNFJJ_02361 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HDFFNFJJ_02362 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HDFFNFJJ_02363 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDFFNFJJ_02364 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDFFNFJJ_02365 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HDFFNFJJ_02366 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDFFNFJJ_02367 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDFFNFJJ_02368 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HDFFNFJJ_02369 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HDFFNFJJ_02370 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDFFNFJJ_02371 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDFFNFJJ_02372 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HDFFNFJJ_02373 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HDFFNFJJ_02374 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HDFFNFJJ_02375 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDFFNFJJ_02376 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HDFFNFJJ_02377 5.4e-138 yphF
HDFFNFJJ_02378 1.6e-18 yphE S Protein of unknown function (DUF2768)
HDFFNFJJ_02379 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDFFNFJJ_02380 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDFFNFJJ_02381 1.6e-28 ypzH
HDFFNFJJ_02382 2.5e-161 seaA S YIEGIA protein
HDFFNFJJ_02383 1.3e-102 yphA
HDFFNFJJ_02384 1e-07 S YpzI-like protein
HDFFNFJJ_02385 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDFFNFJJ_02386 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HDFFNFJJ_02387 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDFFNFJJ_02388 1.8e-23 S Family of unknown function (DUF5359)
HDFFNFJJ_02389 9.2e-113 ypfA M Flagellar protein YcgR
HDFFNFJJ_02390 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HDFFNFJJ_02391 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HDFFNFJJ_02392 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HDFFNFJJ_02393 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HDFFNFJJ_02394 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDFFNFJJ_02395 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HDFFNFJJ_02396 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HDFFNFJJ_02397 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HDFFNFJJ_02398 4.6e-81 ypbE M Lysin motif
HDFFNFJJ_02399 2.2e-100 ypbD S metal-dependent membrane protease
HDFFNFJJ_02400 3.2e-286 recQ 3.6.4.12 L DNA helicase
HDFFNFJJ_02401 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
HDFFNFJJ_02402 4.7e-41 fer C Ferredoxin
HDFFNFJJ_02403 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDFFNFJJ_02404 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFFNFJJ_02405 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDFFNFJJ_02406 6.8e-201 rsiX
HDFFNFJJ_02407 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_02408 0.0 resE 2.7.13.3 T Histidine kinase
HDFFNFJJ_02409 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_02410 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HDFFNFJJ_02411 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HDFFNFJJ_02412 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HDFFNFJJ_02413 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDFFNFJJ_02414 1.9e-87 spmB S Spore maturation protein
HDFFNFJJ_02415 3.5e-103 spmA S Spore maturation protein
HDFFNFJJ_02416 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HDFFNFJJ_02417 4e-98 ypuI S Protein of unknown function (DUF3907)
HDFFNFJJ_02418 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDFFNFJJ_02419 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDFFNFJJ_02420 4.5e-94 ypuF S Domain of unknown function (DUF309)
HDFFNFJJ_02421 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDFFNFJJ_02422 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HDFFNFJJ_02423 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HDFFNFJJ_02424 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HDFFNFJJ_02425 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDFFNFJJ_02426 6e-55 ypuD
HDFFNFJJ_02427 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HDFFNFJJ_02428 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HDFFNFJJ_02429 1.5e-17 S SNARE associated Golgi protein
HDFFNFJJ_02432 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDFFNFJJ_02433 1.3e-149 ypuA S Secreted protein
HDFFNFJJ_02434 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDFFNFJJ_02435 1.4e-273 spoVAF EG Stage V sporulation protein AF
HDFFNFJJ_02436 1.4e-110 spoVAEA S stage V sporulation protein
HDFFNFJJ_02437 2.2e-57 spoVAEB S stage V sporulation protein
HDFFNFJJ_02438 9e-192 spoVAD I Stage V sporulation protein AD
HDFFNFJJ_02439 2.3e-78 spoVAC S stage V sporulation protein AC
HDFFNFJJ_02440 1e-67 spoVAB S Stage V sporulation protein AB
HDFFNFJJ_02441 7.4e-112 spoVAA S Stage V sporulation protein AA
HDFFNFJJ_02442 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDFFNFJJ_02443 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HDFFNFJJ_02444 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HDFFNFJJ_02445 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HDFFNFJJ_02446 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HDFFNFJJ_02447 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HDFFNFJJ_02448 2.6e-166 xerD L recombinase XerD
HDFFNFJJ_02449 3.7e-37 S Protein of unknown function (DUF4227)
HDFFNFJJ_02450 2.4e-80 fur P Belongs to the Fur family
HDFFNFJJ_02451 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HDFFNFJJ_02452 2e-32 yqkK
HDFFNFJJ_02453 5.5e-242 mleA 1.1.1.38 C malic enzyme
HDFFNFJJ_02454 3.1e-235 mleN C Na H antiporter
HDFFNFJJ_02455 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HDFFNFJJ_02456 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HDFFNFJJ_02457 4.5e-58 ansR K Transcriptional regulator
HDFFNFJJ_02458 3e-223 yqxK 3.6.4.12 L DNA helicase
HDFFNFJJ_02459 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HDFFNFJJ_02461 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HDFFNFJJ_02462 4e-14 yqkE S Protein of unknown function (DUF3886)
HDFFNFJJ_02463 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HDFFNFJJ_02464 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HDFFNFJJ_02465 2.8e-54 yqkB S Belongs to the HesB IscA family
HDFFNFJJ_02466 4.7e-196 yqkA K GrpB protein
HDFFNFJJ_02467 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HDFFNFJJ_02468 3.6e-87 yqjY K acetyltransferase
HDFFNFJJ_02469 2.2e-49 S YolD-like protein
HDFFNFJJ_02470 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDFFNFJJ_02472 5.2e-226 yqjV G Major Facilitator Superfamily
HDFFNFJJ_02474 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDFFNFJJ_02475 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HDFFNFJJ_02476 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HDFFNFJJ_02477 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_02478 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HDFFNFJJ_02479 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDFFNFJJ_02480 0.0 rocB E arginine degradation protein
HDFFNFJJ_02481 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HDFFNFJJ_02482 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDFFNFJJ_02483 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDFFNFJJ_02484 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDFFNFJJ_02485 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDFFNFJJ_02486 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDFFNFJJ_02487 4.5e-24 yqzJ
HDFFNFJJ_02488 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDFFNFJJ_02489 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
HDFFNFJJ_02490 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HDFFNFJJ_02491 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HDFFNFJJ_02492 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HDFFNFJJ_02494 1.4e-98 yqjB S protein conserved in bacteria
HDFFNFJJ_02495 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
HDFFNFJJ_02496 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HDFFNFJJ_02497 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HDFFNFJJ_02498 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HDFFNFJJ_02499 9.3e-77 yqiW S Belongs to the UPF0403 family
HDFFNFJJ_02500 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HDFFNFJJ_02501 7.9e-208 norA EGP Major facilitator Superfamily
HDFFNFJJ_02502 2.6e-152 bmrR K helix_turn_helix, mercury resistance
HDFFNFJJ_02503 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDFFNFJJ_02504 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDFFNFJJ_02505 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDFFNFJJ_02506 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDFFNFJJ_02507 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HDFFNFJJ_02508 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDFFNFJJ_02509 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HDFFNFJJ_02510 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HDFFNFJJ_02511 4e-34 yqzF S Protein of unknown function (DUF2627)
HDFFNFJJ_02512 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HDFFNFJJ_02513 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HDFFNFJJ_02514 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HDFFNFJJ_02515 1.8e-212 mmgC I acyl-CoA dehydrogenase
HDFFNFJJ_02516 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
HDFFNFJJ_02517 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HDFFNFJJ_02518 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDFFNFJJ_02519 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HDFFNFJJ_02520 5.9e-27
HDFFNFJJ_02521 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HDFFNFJJ_02523 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HDFFNFJJ_02524 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HDFFNFJJ_02525 0.0 recN L May be involved in recombinational repair of damaged DNA
HDFFNFJJ_02526 1.7e-78 argR K Regulates arginine biosynthesis genes
HDFFNFJJ_02527 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HDFFNFJJ_02528 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDFFNFJJ_02529 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDFFNFJJ_02530 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDFFNFJJ_02531 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDFFNFJJ_02532 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDFFNFJJ_02533 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDFFNFJJ_02534 2.1e-67 yqhY S protein conserved in bacteria
HDFFNFJJ_02535 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HDFFNFJJ_02536 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDFFNFJJ_02537 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HDFFNFJJ_02538 6.9e-103 spoIIIAG S stage III sporulation protein AG
HDFFNFJJ_02539 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HDFFNFJJ_02540 1.3e-197 spoIIIAE S stage III sporulation protein AE
HDFFNFJJ_02541 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HDFFNFJJ_02542 7.6e-29 spoIIIAC S stage III sporulation protein AC
HDFFNFJJ_02543 2.9e-85 spoIIIAB S Stage III sporulation protein
HDFFNFJJ_02544 1.2e-171 spoIIIAA S stage III sporulation protein AA
HDFFNFJJ_02545 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HDFFNFJJ_02546 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDFFNFJJ_02547 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HDFFNFJJ_02548 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HDFFNFJJ_02549 2.3e-93 yqhR S Conserved membrane protein YqhR
HDFFNFJJ_02550 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
HDFFNFJJ_02551 2.2e-61 yqhP
HDFFNFJJ_02552 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HDFFNFJJ_02553 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HDFFNFJJ_02554 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HDFFNFJJ_02555 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HDFFNFJJ_02556 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HDFFNFJJ_02557 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HDFFNFJJ_02558 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HDFFNFJJ_02559 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HDFFNFJJ_02560 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HDFFNFJJ_02561 1.2e-24 sinI S Anti-repressor SinI
HDFFNFJJ_02562 1e-54 sinR K transcriptional
HDFFNFJJ_02563 2.3e-142 tasA S Cell division protein FtsN
HDFFNFJJ_02564 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HDFFNFJJ_02565 2.1e-116 yqxM
HDFFNFJJ_02566 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HDFFNFJJ_02567 1.4e-26 yqzE S YqzE-like protein
HDFFNFJJ_02568 3.7e-42 S ComG operon protein 7
HDFFNFJJ_02569 5.5e-49 comGF U Putative Competence protein ComGF
HDFFNFJJ_02570 1.1e-59 comGE
HDFFNFJJ_02571 4.4e-71 gspH NU protein transport across the cell outer membrane
HDFFNFJJ_02572 1.4e-47 comGC U Required for transformation and DNA binding
HDFFNFJJ_02573 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
HDFFNFJJ_02574 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HDFFNFJJ_02576 7.2e-175 corA P Mg2 transporter protein
HDFFNFJJ_02577 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HDFFNFJJ_02578 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDFFNFJJ_02580 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HDFFNFJJ_02581 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HDFFNFJJ_02582 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HDFFNFJJ_02583 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HDFFNFJJ_02584 6.9e-50 yqgV S Thiamine-binding protein
HDFFNFJJ_02585 2.7e-199 yqgU
HDFFNFJJ_02586 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HDFFNFJJ_02587 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDFFNFJJ_02588 5.2e-181 glcK 2.7.1.2 G Glucokinase
HDFFNFJJ_02589 3.1e-33 yqgQ S Protein conserved in bacteria
HDFFNFJJ_02590 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HDFFNFJJ_02591 2.5e-09 yqgO
HDFFNFJJ_02592 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDFFNFJJ_02593 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDFFNFJJ_02594 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HDFFNFJJ_02596 9.2e-51 yqzD
HDFFNFJJ_02597 1.9e-75 yqzC S YceG-like family
HDFFNFJJ_02598 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDFFNFJJ_02599 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDFFNFJJ_02600 1.3e-157 pstA P Phosphate transport system permease
HDFFNFJJ_02601 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HDFFNFJJ_02602 5.3e-151 pstS P Phosphate
HDFFNFJJ_02603 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HDFFNFJJ_02604 2.5e-231 yqgE EGP Major facilitator superfamily
HDFFNFJJ_02605 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HDFFNFJJ_02606 4e-73 yqgC S protein conserved in bacteria
HDFFNFJJ_02607 8.5e-134 yqgB S Protein of unknown function (DUF1189)
HDFFNFJJ_02608 2.2e-75 yqgA
HDFFNFJJ_02609 5.2e-47 yqfZ M LysM domain
HDFFNFJJ_02610 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HDFFNFJJ_02611 4.3e-62 yqfX S membrane
HDFFNFJJ_02612 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HDFFNFJJ_02613 1.9e-77 zur P Belongs to the Fur family
HDFFNFJJ_02614 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HDFFNFJJ_02615 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HDFFNFJJ_02616 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HDFFNFJJ_02617 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDFFNFJJ_02618 2.9e-14 yqfQ S YqfQ-like protein
HDFFNFJJ_02619 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HDFFNFJJ_02620 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDFFNFJJ_02621 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDFFNFJJ_02622 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HDFFNFJJ_02623 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDFFNFJJ_02624 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDFFNFJJ_02625 4.5e-88 yaiI S Belongs to the UPF0178 family
HDFFNFJJ_02626 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDFFNFJJ_02627 4.5e-112 ccpN K CBS domain
HDFFNFJJ_02628 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDFFNFJJ_02629 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDFFNFJJ_02630 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HDFFNFJJ_02631 8.4e-19 S YqzL-like protein
HDFFNFJJ_02632 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDFFNFJJ_02633 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HDFFNFJJ_02634 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HDFFNFJJ_02635 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDFFNFJJ_02636 0.0 yqfF S membrane-associated HD superfamily hydrolase
HDFFNFJJ_02638 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
HDFFNFJJ_02639 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HDFFNFJJ_02640 2.7e-45 yqfC S sporulation protein YqfC
HDFFNFJJ_02641 6e-25 yqfB
HDFFNFJJ_02642 4.3e-122 yqfA S UPF0365 protein
HDFFNFJJ_02643 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HDFFNFJJ_02644 2.5e-61 yqeY S Yqey-like protein
HDFFNFJJ_02645 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDFFNFJJ_02646 1.6e-158 yqeW P COG1283 Na phosphate symporter
HDFFNFJJ_02647 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HDFFNFJJ_02648 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDFFNFJJ_02649 5.4e-175 prmA J Methylates ribosomal protein L11
HDFFNFJJ_02650 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDFFNFJJ_02651 0.0 dnaK O Heat shock 70 kDa protein
HDFFNFJJ_02652 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDFFNFJJ_02653 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDFFNFJJ_02654 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
HDFFNFJJ_02655 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDFFNFJJ_02656 1e-54 yqxA S Protein of unknown function (DUF3679)
HDFFNFJJ_02657 6.9e-223 spoIIP M stage II sporulation protein P
HDFFNFJJ_02658 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HDFFNFJJ_02659 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HDFFNFJJ_02660 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HDFFNFJJ_02661 4.1e-15 S YqzM-like protein
HDFFNFJJ_02662 0.0 comEC S Competence protein ComEC
HDFFNFJJ_02663 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HDFFNFJJ_02664 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HDFFNFJJ_02665 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDFFNFJJ_02666 2.9e-139 yqeM Q Methyltransferase
HDFFNFJJ_02667 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDFFNFJJ_02668 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HDFFNFJJ_02669 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDFFNFJJ_02670 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HDFFNFJJ_02671 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDFFNFJJ_02672 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HDFFNFJJ_02673 5.3e-95 yqeG S hydrolase of the HAD superfamily
HDFFNFJJ_02675 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HDFFNFJJ_02676 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDFFNFJJ_02677 4.7e-106 yqeD S SNARE associated Golgi protein
HDFFNFJJ_02678 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HDFFNFJJ_02679 2.3e-133 yqeB
HDFFNFJJ_02680 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HDFFNFJJ_02681 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDFFNFJJ_02682 1.4e-281 cisA2 L Recombinase
HDFFNFJJ_02683 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HDFFNFJJ_02684 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
HDFFNFJJ_02685 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDFFNFJJ_02686 1.6e-54 arsR K ArsR family transcriptional regulator
HDFFNFJJ_02687 1.1e-152 yqcI S YqcI/YcgG family
HDFFNFJJ_02688 1.6e-96 S Tetratricopeptide repeat
HDFFNFJJ_02691 3.8e-277 A Pre-toxin TG
HDFFNFJJ_02692 1.1e-104 S Suppressor of fused protein (SUFU)
HDFFNFJJ_02694 5e-60
HDFFNFJJ_02696 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HDFFNFJJ_02697 2.6e-68 S Bacteriophage holin family
HDFFNFJJ_02698 4.8e-165 xepA
HDFFNFJJ_02699 1.3e-23
HDFFNFJJ_02700 4.1e-56 xkdW S XkdW protein
HDFFNFJJ_02701 2e-221
HDFFNFJJ_02702 9.6e-40
HDFFNFJJ_02703 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HDFFNFJJ_02704 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HDFFNFJJ_02705 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HDFFNFJJ_02706 1.8e-38 xkdR S Protein of unknown function (DUF2577)
HDFFNFJJ_02707 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HDFFNFJJ_02708 9e-114 xkdP S Lysin motif
HDFFNFJJ_02709 0.0 xkdO L Transglycosylase SLT domain
HDFFNFJJ_02710 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
HDFFNFJJ_02712 3.6e-76 xkdM S Phage tail tube protein
HDFFNFJJ_02713 5.5e-256 xkdK S Phage tail sheath C-terminal domain
HDFFNFJJ_02714 3.2e-26
HDFFNFJJ_02715 1.4e-77
HDFFNFJJ_02716 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
HDFFNFJJ_02717 6.7e-65 yqbH S Domain of unknown function (DUF3599)
HDFFNFJJ_02718 2.1e-67 S Protein of unknown function (DUF3199)
HDFFNFJJ_02719 3.6e-51 S YqbF, hypothetical protein domain
HDFFNFJJ_02720 1.9e-167 xkdG S Phage capsid family
HDFFNFJJ_02721 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HDFFNFJJ_02722 2e-115
HDFFNFJJ_02723 5.7e-169 S Phage Mu protein F like protein
HDFFNFJJ_02724 5.9e-296 yqbA S portal protein
HDFFNFJJ_02725 2.4e-253 S phage terminase, large subunit
HDFFNFJJ_02726 6.3e-107 yqaS L DNA packaging
HDFFNFJJ_02728 6.5e-81 L Transposase
HDFFNFJJ_02729 1.6e-166
HDFFNFJJ_02730 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
HDFFNFJJ_02731 7.2e-74 rusA L Endodeoxyribonuclease RusA
HDFFNFJJ_02733 5.9e-168 xkdC L IstB-like ATP binding protein
HDFFNFJJ_02734 4.7e-123 3.1.3.16 L DnaD domain protein
HDFFNFJJ_02735 2.5e-155 recT L RecT family
HDFFNFJJ_02736 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
HDFFNFJJ_02740 1.2e-103
HDFFNFJJ_02742 6.5e-37 K Helix-turn-helix XRE-family like proteins
HDFFNFJJ_02743 1.1e-56 K sequence-specific DNA binding
HDFFNFJJ_02745 1e-101 adk 2.7.4.3 F adenylate kinase activity
HDFFNFJJ_02746 1.4e-100 yqaB E IrrE N-terminal-like domain
HDFFNFJJ_02747 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDFFNFJJ_02748 2e-68 psiE S Protein PsiE homolog
HDFFNFJJ_02749 9e-237 yrkQ T Histidine kinase
HDFFNFJJ_02750 1.1e-127 T Transcriptional regulator
HDFFNFJJ_02751 8.2e-224 yrkO P Protein of unknown function (DUF418)
HDFFNFJJ_02752 6e-105 yrkN K Acetyltransferase (GNAT) family
HDFFNFJJ_02753 1.5e-97 ywrO S Flavodoxin-like fold
HDFFNFJJ_02754 2.8e-79 S Protein of unknown function with HXXEE motif
HDFFNFJJ_02755 4.3e-117 yrkJ S membrane transporter protein
HDFFNFJJ_02756 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HDFFNFJJ_02757 2.3e-212 yrkH P Rhodanese Homology Domain
HDFFNFJJ_02758 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HDFFNFJJ_02759 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
HDFFNFJJ_02760 7.8e-39 yrkD S protein conserved in bacteria
HDFFNFJJ_02761 2.6e-108 yrkC G Cupin domain
HDFFNFJJ_02762 4.8e-151 bltR K helix_turn_helix, mercury resistance
HDFFNFJJ_02763 3.5e-211 blt EGP Major facilitator Superfamily
HDFFNFJJ_02764 1.4e-83 bltD 2.3.1.57 K FR47-like protein
HDFFNFJJ_02765 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HDFFNFJJ_02766 2.1e-17 S YrzO-like protein
HDFFNFJJ_02767 1.7e-171 yrdR EG EamA-like transporter family
HDFFNFJJ_02768 5.9e-160 yrdQ K Transcriptional regulator
HDFFNFJJ_02769 2e-199 trkA P Oxidoreductase
HDFFNFJJ_02770 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
HDFFNFJJ_02771 1.3e-66 yodA S tautomerase
HDFFNFJJ_02772 7.7e-163 gltR K LysR substrate binding domain
HDFFNFJJ_02774 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
HDFFNFJJ_02775 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HDFFNFJJ_02776 3.3e-138 azlC E AzlC protein
HDFFNFJJ_02777 2.2e-79 bkdR K helix_turn_helix ASNC type
HDFFNFJJ_02778 4.1e-46 yrdF K ribonuclease inhibitor
HDFFNFJJ_02779 4.1e-231 cypA C Cytochrome P450
HDFFNFJJ_02780 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
HDFFNFJJ_02781 1.9e-57 S Protein of unknown function (DUF2568)
HDFFNFJJ_02782 1.2e-91 yrdA S DinB family
HDFFNFJJ_02783 7.6e-168 aadK G Streptomycin adenylyltransferase
HDFFNFJJ_02784 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HDFFNFJJ_02785 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDFFNFJJ_02786 3e-125 yrpD S Domain of unknown function, YrpD
HDFFNFJJ_02788 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HDFFNFJJ_02789 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_02790 4.5e-188 yrpG C Aldo/keto reductase family
HDFFNFJJ_02791 9.5e-226 yraO C Citrate transporter
HDFFNFJJ_02792 1.2e-163 yraN K Transcriptional regulator
HDFFNFJJ_02793 2.4e-206 yraM S PrpF protein
HDFFNFJJ_02795 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HDFFNFJJ_02796 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDFFNFJJ_02797 3.2e-155 S Alpha beta hydrolase
HDFFNFJJ_02798 1.7e-60 T sh3 domain protein
HDFFNFJJ_02799 2.4e-61 T sh3 domain protein
HDFFNFJJ_02800 1.3e-66 E Glyoxalase-like domain
HDFFNFJJ_02801 5.3e-37 yraG
HDFFNFJJ_02802 6.4e-63 yraF M Spore coat protein
HDFFNFJJ_02803 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HDFFNFJJ_02804 2.6e-26 yraE
HDFFNFJJ_02805 1.1e-49 yraD M Spore coat protein
HDFFNFJJ_02806 4.3e-47 yraB K helix_turn_helix, mercury resistance
HDFFNFJJ_02807 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
HDFFNFJJ_02808 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
HDFFNFJJ_02809 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HDFFNFJJ_02810 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HDFFNFJJ_02811 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HDFFNFJJ_02812 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HDFFNFJJ_02813 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HDFFNFJJ_02814 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HDFFNFJJ_02815 0.0 levR K PTS system fructose IIA component
HDFFNFJJ_02816 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HDFFNFJJ_02817 3.6e-106 yrhP E LysE type translocator
HDFFNFJJ_02818 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HDFFNFJJ_02819 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_02820 1.7e-151 rsiV S Protein of unknown function (DUF3298)
HDFFNFJJ_02821 0.0 yrhL I Acyltransferase family
HDFFNFJJ_02822 1.5e-46 yrhK S YrhK-like protein
HDFFNFJJ_02823 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HDFFNFJJ_02824 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HDFFNFJJ_02825 4.5e-97 yrhH Q methyltransferase
HDFFNFJJ_02828 1.8e-142 focA P Formate nitrite
HDFFNFJJ_02829 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HDFFNFJJ_02830 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HDFFNFJJ_02831 1.4e-78 yrhD S Protein of unknown function (DUF1641)
HDFFNFJJ_02832 4.6e-35 yrhC S YrhC-like protein
HDFFNFJJ_02833 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDFFNFJJ_02834 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HDFFNFJJ_02835 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDFFNFJJ_02836 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HDFFNFJJ_02837 7e-27 yrzA S Protein of unknown function (DUF2536)
HDFFNFJJ_02838 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HDFFNFJJ_02839 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HDFFNFJJ_02840 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDFFNFJJ_02841 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HDFFNFJJ_02842 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HDFFNFJJ_02843 7.8e-174 yegQ O Peptidase U32
HDFFNFJJ_02844 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
HDFFNFJJ_02845 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDFFNFJJ_02846 1.2e-45 yrzB S Belongs to the UPF0473 family
HDFFNFJJ_02847 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDFFNFJJ_02848 1.7e-41 yrzL S Belongs to the UPF0297 family
HDFFNFJJ_02849 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDFFNFJJ_02850 2.7e-170 yrrI S AI-2E family transporter
HDFFNFJJ_02851 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HDFFNFJJ_02852 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
HDFFNFJJ_02853 3.6e-109 gluC P ABC transporter
HDFFNFJJ_02854 7.6e-107 glnP P ABC transporter
HDFFNFJJ_02855 8e-08 S Protein of unknown function (DUF3918)
HDFFNFJJ_02856 9.8e-31 yrzR
HDFFNFJJ_02857 1.8e-83 yrrD S protein conserved in bacteria
HDFFNFJJ_02858 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDFFNFJJ_02859 1.4e-15 S COG0457 FOG TPR repeat
HDFFNFJJ_02860 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDFFNFJJ_02861 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
HDFFNFJJ_02862 1.2e-70 cymR K Transcriptional regulator
HDFFNFJJ_02863 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HDFFNFJJ_02864 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HDFFNFJJ_02865 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HDFFNFJJ_02866 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDFFNFJJ_02868 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
HDFFNFJJ_02869 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDFFNFJJ_02870 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDFFNFJJ_02871 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDFFNFJJ_02872 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HDFFNFJJ_02873 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HDFFNFJJ_02874 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HDFFNFJJ_02875 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HDFFNFJJ_02876 9.4e-49 yrzD S Post-transcriptional regulator
HDFFNFJJ_02877 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDFFNFJJ_02878 2.2e-114 yrbG S membrane
HDFFNFJJ_02879 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HDFFNFJJ_02880 1.1e-38 yajC U Preprotein translocase subunit YajC
HDFFNFJJ_02881 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDFFNFJJ_02882 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDFFNFJJ_02883 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HDFFNFJJ_02884 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDFFNFJJ_02885 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDFFNFJJ_02886 4.8e-93 bofC S BofC C-terminal domain
HDFFNFJJ_02887 5.3e-253 csbX EGP Major facilitator Superfamily
HDFFNFJJ_02888 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HDFFNFJJ_02889 6.5e-119 yrzF T serine threonine protein kinase
HDFFNFJJ_02891 2.6e-35 S Family of unknown function (DUF5412)
HDFFNFJJ_02892 1.8e-262 alsT E Sodium alanine symporter
HDFFNFJJ_02893 1.9e-127 yebC K transcriptional regulatory protein
HDFFNFJJ_02894 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDFFNFJJ_02895 9.8e-158 safA M spore coat assembly protein SafA
HDFFNFJJ_02896 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HDFFNFJJ_02897 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HDFFNFJJ_02898 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HDFFNFJJ_02899 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
HDFFNFJJ_02900 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HDFFNFJJ_02901 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HDFFNFJJ_02902 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HDFFNFJJ_02903 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDFFNFJJ_02904 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HDFFNFJJ_02905 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDFFNFJJ_02906 4.1e-56 ysxB J ribosomal protein
HDFFNFJJ_02907 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDFFNFJJ_02908 9.2e-161 spoIVFB S Stage IV sporulation protein
HDFFNFJJ_02909 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HDFFNFJJ_02910 2.5e-144 minD D Belongs to the ParA family
HDFFNFJJ_02911 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDFFNFJJ_02912 1.4e-84 mreD M shape-determining protein
HDFFNFJJ_02913 2.8e-157 mreC M Involved in formation and maintenance of cell shape
HDFFNFJJ_02914 1.8e-184 mreB D Rod shape-determining protein MreB
HDFFNFJJ_02915 5.9e-126 radC E Belongs to the UPF0758 family
HDFFNFJJ_02916 2.8e-102 maf D septum formation protein Maf
HDFFNFJJ_02917 1.1e-168 spoIIB S Sporulation related domain
HDFFNFJJ_02918 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HDFFNFJJ_02919 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDFFNFJJ_02920 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDFFNFJJ_02921 1.6e-25
HDFFNFJJ_02922 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HDFFNFJJ_02923 1.9e-226 spoVID M stage VI sporulation protein D
HDFFNFJJ_02924 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HDFFNFJJ_02925 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
HDFFNFJJ_02926 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HDFFNFJJ_02927 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HDFFNFJJ_02928 3.6e-146 hemX O cytochrome C
HDFFNFJJ_02929 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HDFFNFJJ_02930 1.4e-89 ysxD
HDFFNFJJ_02931 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HDFFNFJJ_02932 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HDFFNFJJ_02933 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HDFFNFJJ_02934 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDFFNFJJ_02935 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDFFNFJJ_02936 2.3e-187 ysoA H Tetratricopeptide repeat
HDFFNFJJ_02937 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDFFNFJJ_02938 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDFFNFJJ_02939 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HDFFNFJJ_02940 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDFFNFJJ_02941 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HDFFNFJJ_02942 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HDFFNFJJ_02943 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HDFFNFJJ_02945 7.6e-82 ysnE K acetyltransferase
HDFFNFJJ_02946 9.1e-134 ysnF S protein conserved in bacteria
HDFFNFJJ_02948 1.4e-92 ysnB S Phosphoesterase
HDFFNFJJ_02949 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDFFNFJJ_02950 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HDFFNFJJ_02951 2.9e-196 gerM S COG5401 Spore germination protein
HDFFNFJJ_02952 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDFFNFJJ_02953 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_02954 3.3e-30 gerE K Transcriptional regulator
HDFFNFJJ_02955 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HDFFNFJJ_02956 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HDFFNFJJ_02957 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HDFFNFJJ_02958 2.4e-107 sdhC C succinate dehydrogenase
HDFFNFJJ_02959 1.2e-79 yslB S Protein of unknown function (DUF2507)
HDFFNFJJ_02960 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HDFFNFJJ_02961 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDFFNFJJ_02962 2e-52 trxA O Belongs to the thioredoxin family
HDFFNFJJ_02963 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HDFFNFJJ_02965 4.2e-178 etfA C Electron transfer flavoprotein
HDFFNFJJ_02966 1.2e-135 etfB C Electron transfer flavoprotein
HDFFNFJJ_02967 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HDFFNFJJ_02968 2.7e-100 fadR K Transcriptional regulator
HDFFNFJJ_02969 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HDFFNFJJ_02970 7.3e-68 yshE S membrane
HDFFNFJJ_02971 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDFFNFJJ_02972 0.0 polX L COG1796 DNA polymerase IV (family X)
HDFFNFJJ_02973 1.3e-85 cvpA S membrane protein, required for colicin V production
HDFFNFJJ_02974 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDFFNFJJ_02975 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDFFNFJJ_02976 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDFFNFJJ_02977 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDFFNFJJ_02978 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDFFNFJJ_02979 2.6e-32 sspI S Belongs to the SspI family
HDFFNFJJ_02980 4.4e-208 ysfB KT regulator
HDFFNFJJ_02981 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
HDFFNFJJ_02982 5.6e-258 glcF C Glycolate oxidase
HDFFNFJJ_02983 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
HDFFNFJJ_02985 0.0 cstA T Carbon starvation protein
HDFFNFJJ_02986 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HDFFNFJJ_02987 3.4e-144 araQ G transport system permease
HDFFNFJJ_02988 1.4e-167 araP G carbohydrate transport
HDFFNFJJ_02989 2.8e-254 araN G carbohydrate transport
HDFFNFJJ_02990 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HDFFNFJJ_02991 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HDFFNFJJ_02992 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HDFFNFJJ_02993 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HDFFNFJJ_02994 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HDFFNFJJ_02995 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HDFFNFJJ_02996 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HDFFNFJJ_02997 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HDFFNFJJ_02998 7.5e-45 ysdA S Membrane
HDFFNFJJ_02999 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDFFNFJJ_03000 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDFFNFJJ_03001 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDFFNFJJ_03003 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HDFFNFJJ_03004 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HDFFNFJJ_03005 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HDFFNFJJ_03006 0.0 lytS 2.7.13.3 T Histidine kinase
HDFFNFJJ_03007 1.5e-149 ysaA S HAD-hyrolase-like
HDFFNFJJ_03008 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDFFNFJJ_03009 3.8e-159 ytxC S YtxC-like family
HDFFNFJJ_03010 4.9e-111 ytxB S SNARE associated Golgi protein
HDFFNFJJ_03011 3e-173 dnaI L Primosomal protein DnaI
HDFFNFJJ_03012 3.5e-266 dnaB L Membrane attachment protein
HDFFNFJJ_03013 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDFFNFJJ_03014 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HDFFNFJJ_03015 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDFFNFJJ_03016 9.9e-67 ytcD K Transcriptional regulator
HDFFNFJJ_03017 4.9e-205 ytbD EGP Major facilitator Superfamily
HDFFNFJJ_03018 8.9e-161 ytbE S reductase
HDFFNFJJ_03019 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDFFNFJJ_03020 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HDFFNFJJ_03021 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDFFNFJJ_03022 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDFFNFJJ_03023 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HDFFNFJJ_03024 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_03025 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HDFFNFJJ_03026 1.8e-242 icd 1.1.1.42 C isocitrate
HDFFNFJJ_03027 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HDFFNFJJ_03028 4.7e-71 yeaL S membrane
HDFFNFJJ_03029 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HDFFNFJJ_03030 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HDFFNFJJ_03031 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDFFNFJJ_03032 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDFFNFJJ_03033 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HDFFNFJJ_03034 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDFFNFJJ_03035 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HDFFNFJJ_03036 0.0 dnaE 2.7.7.7 L DNA polymerase
HDFFNFJJ_03037 3.2e-56 ytrH S Sporulation protein YtrH
HDFFNFJJ_03038 8.2e-69 ytrI
HDFFNFJJ_03039 9.2e-29
HDFFNFJJ_03040 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HDFFNFJJ_03041 2.4e-47 ytpI S YtpI-like protein
HDFFNFJJ_03042 8e-241 ytoI K transcriptional regulator containing CBS domains
HDFFNFJJ_03043 1.2e-158 ytnM S membrane transporter protein
HDFFNFJJ_03044 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
HDFFNFJJ_03045 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HDFFNFJJ_03046 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDFFNFJJ_03047 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HDFFNFJJ_03048 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDFFNFJJ_03049 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HDFFNFJJ_03050 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
HDFFNFJJ_03051 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HDFFNFJJ_03052 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
HDFFNFJJ_03053 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
HDFFNFJJ_03054 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
HDFFNFJJ_03055 2.9e-173 ytlI K LysR substrate binding domain
HDFFNFJJ_03056 1.7e-130 ytkL S Belongs to the UPF0173 family
HDFFNFJJ_03057 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_03059 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
HDFFNFJJ_03060 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDFFNFJJ_03061 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HDFFNFJJ_03062 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDFFNFJJ_03063 7e-165 ytxK 2.1.1.72 L DNA methylase
HDFFNFJJ_03064 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDFFNFJJ_03065 8.7e-70 ytfJ S Sporulation protein YtfJ
HDFFNFJJ_03066 5.6e-116 ytfI S Protein of unknown function (DUF2953)
HDFFNFJJ_03067 1.3e-87 yteJ S RDD family
HDFFNFJJ_03068 2.4e-181 sppA OU signal peptide peptidase SppA
HDFFNFJJ_03069 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDFFNFJJ_03070 0.0 ytcJ S amidohydrolase
HDFFNFJJ_03071 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HDFFNFJJ_03072 2e-29 sspB S spore protein
HDFFNFJJ_03073 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDFFNFJJ_03074 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
HDFFNFJJ_03075 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HDFFNFJJ_03076 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDFFNFJJ_03077 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HDFFNFJJ_03078 3.4e-109 yttP K Transcriptional regulator
HDFFNFJJ_03079 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HDFFNFJJ_03080 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HDFFNFJJ_03081 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDFFNFJJ_03083 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDFFNFJJ_03084 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HDFFNFJJ_03085 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HDFFNFJJ_03086 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HDFFNFJJ_03087 1.9e-225 acuC BQ histone deacetylase
HDFFNFJJ_03088 1.4e-125 motS N Flagellar motor protein
HDFFNFJJ_03089 7.1e-147 motA N flagellar motor
HDFFNFJJ_03090 1.7e-182 ccpA K catabolite control protein A
HDFFNFJJ_03091 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HDFFNFJJ_03092 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
HDFFNFJJ_03093 6.6e-17 ytxH S COG4980 Gas vesicle protein
HDFFNFJJ_03094 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDFFNFJJ_03095 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDFFNFJJ_03096 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HDFFNFJJ_03097 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDFFNFJJ_03098 9.8e-149 ytpQ S Belongs to the UPF0354 family
HDFFNFJJ_03099 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDFFNFJJ_03100 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HDFFNFJJ_03101 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HDFFNFJJ_03102 9.8e-52 ytzB S small secreted protein
HDFFNFJJ_03103 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HDFFNFJJ_03104 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HDFFNFJJ_03105 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDFFNFJJ_03106 2e-45 ytzH S YtzH-like protein
HDFFNFJJ_03107 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HDFFNFJJ_03108 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HDFFNFJJ_03109 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HDFFNFJJ_03110 1.3e-165 ytlQ
HDFFNFJJ_03111 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HDFFNFJJ_03112 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDFFNFJJ_03113 7.1e-272 pepV 3.5.1.18 E Dipeptidase
HDFFNFJJ_03114 7.2e-226 pbuO S permease
HDFFNFJJ_03115 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
HDFFNFJJ_03116 4.3e-132 ythP V ABC transporter
HDFFNFJJ_03117 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HDFFNFJJ_03118 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDFFNFJJ_03119 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDFFNFJJ_03120 8.2e-232 ytfP S HI0933-like protein
HDFFNFJJ_03121 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HDFFNFJJ_03122 3.1e-26 yteV S Sporulation protein Cse60
HDFFNFJJ_03123 4.8e-117 yteU S Integral membrane protein
HDFFNFJJ_03124 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HDFFNFJJ_03125 4.6e-73 yteS G transport
HDFFNFJJ_03126 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HDFFNFJJ_03127 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HDFFNFJJ_03128 0.0 ytdP K Transcriptional regulator
HDFFNFJJ_03129 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HDFFNFJJ_03130 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HDFFNFJJ_03131 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HDFFNFJJ_03132 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
HDFFNFJJ_03133 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HDFFNFJJ_03134 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HDFFNFJJ_03135 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HDFFNFJJ_03136 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HDFFNFJJ_03137 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HDFFNFJJ_03138 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
HDFFNFJJ_03139 2.3e-190 msmR K Transcriptional regulator
HDFFNFJJ_03140 2.3e-248 msmE G Bacterial extracellular solute-binding protein
HDFFNFJJ_03141 3.7e-168 amyD P ABC transporter
HDFFNFJJ_03142 1.5e-144 amyC P ABC transporter (permease)
HDFFNFJJ_03143 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HDFFNFJJ_03144 2.1e-51 ytwF P Sulfurtransferase
HDFFNFJJ_03145 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDFFNFJJ_03146 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HDFFNFJJ_03147 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HDFFNFJJ_03148 2.1e-211 yttB EGP Major facilitator Superfamily
HDFFNFJJ_03149 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HDFFNFJJ_03150 0.0 bceB V ABC transporter (permease)
HDFFNFJJ_03151 1.1e-138 bceA V ABC transporter, ATP-binding protein
HDFFNFJJ_03152 5.6e-186 T PhoQ Sensor
HDFFNFJJ_03153 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_03154 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HDFFNFJJ_03155 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HDFFNFJJ_03156 5.9e-148
HDFFNFJJ_03157 6.1e-169 P ABC-2 family transporter protein
HDFFNFJJ_03158 1.1e-161 ytrB P abc transporter atp-binding protein
HDFFNFJJ_03159 5.1e-66 ytrA K GntR family transcriptional regulator
HDFFNFJJ_03161 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HDFFNFJJ_03162 2.1e-190 yhcC S Fe-S oxidoreductase
HDFFNFJJ_03163 3.3e-106 ytqB J Putative rRNA methylase
HDFFNFJJ_03164 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HDFFNFJJ_03165 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HDFFNFJJ_03166 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HDFFNFJJ_03167 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HDFFNFJJ_03168 0.0 asnB 6.3.5.4 E Asparagine synthase
HDFFNFJJ_03169 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDFFNFJJ_03170 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HDFFNFJJ_03171 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HDFFNFJJ_03172 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HDFFNFJJ_03173 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HDFFNFJJ_03174 1.4e-144 ytlC P ABC transporter
HDFFNFJJ_03175 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HDFFNFJJ_03176 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HDFFNFJJ_03177 5.4e-63 ytkC S Bacteriophage holin family
HDFFNFJJ_03178 2.1e-76 dps P Belongs to the Dps family
HDFFNFJJ_03180 3.6e-73 ytkA S YtkA-like
HDFFNFJJ_03181 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDFFNFJJ_03182 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HDFFNFJJ_03183 3.6e-41 rpmE2 J Ribosomal protein L31
HDFFNFJJ_03184 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
HDFFNFJJ_03185 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HDFFNFJJ_03186 1.1e-24 S Domain of Unknown Function (DUF1540)
HDFFNFJJ_03187 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HDFFNFJJ_03188 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HDFFNFJJ_03189 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HDFFNFJJ_03190 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
HDFFNFJJ_03191 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HDFFNFJJ_03192 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HDFFNFJJ_03193 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HDFFNFJJ_03194 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HDFFNFJJ_03195 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HDFFNFJJ_03196 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
HDFFNFJJ_03197 2.6e-132 dksA T COG1734 DnaK suppressor protein
HDFFNFJJ_03198 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HDFFNFJJ_03199 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDFFNFJJ_03200 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HDFFNFJJ_03201 3.6e-235 ytcC M Glycosyltransferase Family 4
HDFFNFJJ_03203 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HDFFNFJJ_03204 1.8e-217 cotSA M Glycosyl transferases group 1
HDFFNFJJ_03205 1.8e-206 cotI S Spore coat protein
HDFFNFJJ_03206 9.9e-77 tspO T membrane
HDFFNFJJ_03207 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDFFNFJJ_03208 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDFFNFJJ_03209 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HDFFNFJJ_03210 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDFFNFJJ_03211 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDFFNFJJ_03220 7.8e-08
HDFFNFJJ_03221 1.3e-09
HDFFNFJJ_03228 2e-08
HDFFNFJJ_03233 7.8e-08
HDFFNFJJ_03235 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HDFFNFJJ_03236 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HDFFNFJJ_03237 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HDFFNFJJ_03238 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDFFNFJJ_03239 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDFFNFJJ_03240 0.0 ydiF S ABC transporter
HDFFNFJJ_03241 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HDFFNFJJ_03242 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDFFNFJJ_03243 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HDFFNFJJ_03244 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDFFNFJJ_03245 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HDFFNFJJ_03246 7.9e-129 ydiL S CAAX protease self-immunity
HDFFNFJJ_03247 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDFFNFJJ_03248 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDFFNFJJ_03250 6.4e-66 KL Phage plasmid primase P4 family
HDFFNFJJ_03251 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HDFFNFJJ_03252 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HDFFNFJJ_03254 1.2e-199 V AAA domain (dynein-related subfamily)
HDFFNFJJ_03255 4.9e-257 J LlaJI restriction endonuclease
HDFFNFJJ_03256 1.1e-08 ydjC S Abhydrolase domain containing 18
HDFFNFJJ_03257 0.0 K NB-ARC domain
HDFFNFJJ_03258 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
HDFFNFJJ_03259 7.1e-256 gutA G MFS/sugar transport protein
HDFFNFJJ_03260 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HDFFNFJJ_03261 5.1e-114 pspA KT Phage shock protein A
HDFFNFJJ_03262 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDFFNFJJ_03263 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HDFFNFJJ_03264 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
HDFFNFJJ_03265 4.7e-196 S Ion transport 2 domain protein
HDFFNFJJ_03266 2.7e-258 iolT EGP Major facilitator Superfamily
HDFFNFJJ_03267 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HDFFNFJJ_03268 4.5e-64 ydjM M Lytic transglycolase
HDFFNFJJ_03269 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
HDFFNFJJ_03271 1.4e-34 ydjO S Cold-inducible protein YdjO
HDFFNFJJ_03272 9.5e-160 ydjP I Alpha/beta hydrolase family
HDFFNFJJ_03273 2.4e-181 yeaA S Protein of unknown function (DUF4003)
HDFFNFJJ_03274 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HDFFNFJJ_03275 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HDFFNFJJ_03276 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDFFNFJJ_03277 1.6e-177 yeaC S COG0714 MoxR-like ATPases
HDFFNFJJ_03278 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HDFFNFJJ_03279 0.0 yebA E COG1305 Transglutaminase-like enzymes
HDFFNFJJ_03280 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDFFNFJJ_03281 6e-212 pbuG S permease
HDFFNFJJ_03282 1.1e-118 yebC M Membrane
HDFFNFJJ_03284 4e-93 yebE S UPF0316 protein
HDFFNFJJ_03285 8e-28 yebG S NETI protein
HDFFNFJJ_03286 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDFFNFJJ_03287 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDFFNFJJ_03288 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDFFNFJJ_03289 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HDFFNFJJ_03290 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDFFNFJJ_03291 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDFFNFJJ_03292 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDFFNFJJ_03293 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDFFNFJJ_03294 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HDFFNFJJ_03295 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDFFNFJJ_03296 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HDFFNFJJ_03297 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HDFFNFJJ_03298 3.5e-73 K helix_turn_helix ASNC type
HDFFNFJJ_03299 2.3e-232 yjeH E Amino acid permease
HDFFNFJJ_03300 2.7e-27 S Protein of unknown function (DUF2892)
HDFFNFJJ_03301 0.0 yerA 3.5.4.2 F adenine deaminase
HDFFNFJJ_03302 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
HDFFNFJJ_03303 4.8e-51 yerC S protein conserved in bacteria
HDFFNFJJ_03304 2.7e-304 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HDFFNFJJ_03306 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HDFFNFJJ_03307 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDFFNFJJ_03308 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDFFNFJJ_03309 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HDFFNFJJ_03310 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
HDFFNFJJ_03311 1.6e-123 sapB S MgtC SapB transporter
HDFFNFJJ_03312 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDFFNFJJ_03313 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDFFNFJJ_03314 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDFFNFJJ_03315 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDFFNFJJ_03316 4e-156 yerO K Transcriptional regulator
HDFFNFJJ_03317 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDFFNFJJ_03318 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HDFFNFJJ_03319 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDFFNFJJ_03320 3.2e-98 L Recombinase
HDFFNFJJ_03321 3.2e-53 L Resolvase, N terminal domain
HDFFNFJJ_03322 0.0 yeeA V Type II restriction enzyme, methylase subunits
HDFFNFJJ_03323 0.0 yeeB L DEAD-like helicases superfamily
HDFFNFJJ_03324 1.8e-212 pstS P T5orf172
HDFFNFJJ_03326 6.2e-31 S Colicin immunity protein / pyocin immunity protein
HDFFNFJJ_03327 5.5e-83 S Protein of unknown function, DUF600
HDFFNFJJ_03328 0.0 L nucleic acid phosphodiester bond hydrolysis
HDFFNFJJ_03329 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
HDFFNFJJ_03330 5.5e-214 S Tetratricopeptide repeat
HDFFNFJJ_03332 9.4e-127 yeeN K transcriptional regulatory protein
HDFFNFJJ_03334 1.2e-103 dhaR3 K Transcriptional regulator
HDFFNFJJ_03335 9.7e-82 yesE S SnoaL-like domain
HDFFNFJJ_03336 2.2e-159 yesF GM NAD(P)H-binding
HDFFNFJJ_03337 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HDFFNFJJ_03338 1.5e-45 cotJB S CotJB protein
HDFFNFJJ_03339 5.2e-104 cotJC P Spore Coat
HDFFNFJJ_03340 4.2e-103 yesJ K Acetyltransferase (GNAT) family
HDFFNFJJ_03342 4.4e-104 yesL S Protein of unknown function, DUF624
HDFFNFJJ_03343 0.0 yesM 2.7.13.3 T Histidine kinase
HDFFNFJJ_03344 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
HDFFNFJJ_03345 5e-248 yesO G Bacterial extracellular solute-binding protein
HDFFNFJJ_03346 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HDFFNFJJ_03347 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
HDFFNFJJ_03348 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HDFFNFJJ_03349 0.0 yesS K Transcriptional regulator
HDFFNFJJ_03350 3.8e-133 E GDSL-like Lipase/Acylhydrolase
HDFFNFJJ_03351 8.9e-132 yesU S Domain of unknown function (DUF1961)
HDFFNFJJ_03352 1e-113 yesV S Protein of unknown function, DUF624
HDFFNFJJ_03353 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HDFFNFJJ_03354 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HDFFNFJJ_03355 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
HDFFNFJJ_03356 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HDFFNFJJ_03357 0.0 yetA
HDFFNFJJ_03358 9.6e-291 lplA G Bacterial extracellular solute-binding protein
HDFFNFJJ_03359 1.7e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HDFFNFJJ_03360 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HDFFNFJJ_03361 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HDFFNFJJ_03362 6.1e-123 yetF S membrane
HDFFNFJJ_03363 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HDFFNFJJ_03364 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDFFNFJJ_03365 2.2e-34
HDFFNFJJ_03366 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDFFNFJJ_03367 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDFFNFJJ_03368 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HDFFNFJJ_03369 5.3e-105 yetJ S Belongs to the BI1 family
HDFFNFJJ_03370 5.4e-159 yetK EG EamA-like transporter family
HDFFNFJJ_03371 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_03372 7.8e-213 yetM CH FAD binding domain
HDFFNFJJ_03373 3.6e-199 yetN S Protein of unknown function (DUF3900)
HDFFNFJJ_03374 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HDFFNFJJ_03375 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDFFNFJJ_03376 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HDFFNFJJ_03377 1.9e-172 yfnG 4.2.1.45 M dehydratase
HDFFNFJJ_03378 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
HDFFNFJJ_03379 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HDFFNFJJ_03380 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
HDFFNFJJ_03381 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HDFFNFJJ_03382 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDFFNFJJ_03383 1.3e-241 yfnA E amino acid
HDFFNFJJ_03384 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDFFNFJJ_03385 1.1e-113 yfmS NT chemotaxis protein
HDFFNFJJ_03386 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDFFNFJJ_03387 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
HDFFNFJJ_03388 2.8e-70 yfmP K transcriptional
HDFFNFJJ_03389 1.5e-209 yfmO EGP Major facilitator Superfamily
HDFFNFJJ_03390 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDFFNFJJ_03391 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HDFFNFJJ_03392 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
HDFFNFJJ_03393 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
HDFFNFJJ_03394 7.7e-214 G Major Facilitator Superfamily
HDFFNFJJ_03395 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
HDFFNFJJ_03396 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HDFFNFJJ_03397 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_03398 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_03399 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HDFFNFJJ_03400 2.9e-24 S Protein of unknown function (DUF3212)
HDFFNFJJ_03401 7.6e-58 yflT S Heat induced stress protein YflT
HDFFNFJJ_03402 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HDFFNFJJ_03403 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HDFFNFJJ_03404 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HDFFNFJJ_03405 8.9e-119 citT T response regulator
HDFFNFJJ_03406 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
HDFFNFJJ_03408 8.5e-227 citM C Citrate transporter
HDFFNFJJ_03409 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HDFFNFJJ_03410 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HDFFNFJJ_03411 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDFFNFJJ_03412 9e-124 yflK S protein conserved in bacteria
HDFFNFJJ_03413 4e-18 yflJ S Protein of unknown function (DUF2639)
HDFFNFJJ_03414 4.1e-19 yflI
HDFFNFJJ_03415 2.4e-50 yflH S Protein of unknown function (DUF3243)
HDFFNFJJ_03416 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HDFFNFJJ_03417 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HDFFNFJJ_03418 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDFFNFJJ_03419 6e-67 yhdN S Domain of unknown function (DUF1992)
HDFFNFJJ_03420 3.2e-256 agcS_1 E Sodium alanine symporter
HDFFNFJJ_03421 1.6e-194 E Spore germination protein
HDFFNFJJ_03423 5.1e-207 yfkR S spore germination
HDFFNFJJ_03424 1.5e-283 yfkQ EG Spore germination protein
HDFFNFJJ_03425 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFFNFJJ_03426 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HDFFNFJJ_03427 1.8e-133 treR K transcriptional
HDFFNFJJ_03428 1.6e-125 yfkO C nitroreductase
HDFFNFJJ_03429 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDFFNFJJ_03430 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HDFFNFJJ_03431 6.8e-207 ydiM EGP Major facilitator Superfamily
HDFFNFJJ_03432 2.1e-29 yfkK S Belongs to the UPF0435 family
HDFFNFJJ_03433 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDFFNFJJ_03434 8.4e-51 yfkI S gas vesicle protein
HDFFNFJJ_03435 9.7e-144 yihY S Belongs to the UPF0761 family
HDFFNFJJ_03436 5e-08
HDFFNFJJ_03437 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HDFFNFJJ_03438 6.1e-183 cax P COG0387 Ca2 H antiporter
HDFFNFJJ_03439 1.2e-146 yfkD S YfkD-like protein
HDFFNFJJ_03440 6e-149 yfkC M Mechanosensitive ion channel
HDFFNFJJ_03441 5.4e-222 yfkA S YfkB-like domain
HDFFNFJJ_03442 1.1e-26 yfjT
HDFFNFJJ_03443 2.6e-154 pdaA G deacetylase
HDFFNFJJ_03444 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HDFFNFJJ_03445 1.7e-184 corA P Mediates influx of magnesium ions
HDFFNFJJ_03446 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HDFFNFJJ_03447 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDFFNFJJ_03448 1.6e-39 S YfzA-like protein
HDFFNFJJ_03449 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDFFNFJJ_03450 3.9e-86 yfjM S Psort location Cytoplasmic, score
HDFFNFJJ_03451 3e-29 yfjL
HDFFNFJJ_03452 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDFFNFJJ_03453 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDFFNFJJ_03454 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDFFNFJJ_03455 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDFFNFJJ_03456 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HDFFNFJJ_03457 1.2e-25 sspH S Belongs to the SspH family
HDFFNFJJ_03458 4e-56 yfjF S UPF0060 membrane protein
HDFFNFJJ_03459 1.3e-80 S Family of unknown function (DUF5381)
HDFFNFJJ_03460 1.8e-101 yfjD S Family of unknown function (DUF5381)
HDFFNFJJ_03461 4.1e-144 yfjC
HDFFNFJJ_03462 9.2e-191 yfjB
HDFFNFJJ_03463 1.1e-44 yfjA S Belongs to the WXG100 family
HDFFNFJJ_03464 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HDFFNFJJ_03465 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
HDFFNFJJ_03466 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFFNFJJ_03467 2.1e-310 yfiB3 V ABC transporter
HDFFNFJJ_03468 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDFFNFJJ_03469 9.8e-65 mhqP S DoxX
HDFFNFJJ_03470 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HDFFNFJJ_03471 1.5e-177 K AraC-like ligand binding domain
HDFFNFJJ_03472 1.8e-262 iolT EGP Major facilitator Superfamily
HDFFNFJJ_03473 8.4e-184 G Xylose isomerase
HDFFNFJJ_03474 1.1e-233 S Oxidoreductase
HDFFNFJJ_03476 1.1e-214 yxjM T Histidine kinase
HDFFNFJJ_03477 3.2e-113 KT LuxR family transcriptional regulator
HDFFNFJJ_03478 6.2e-171 V ABC transporter, ATP-binding protein
HDFFNFJJ_03479 9.8e-214 V ABC-2 family transporter protein
HDFFNFJJ_03480 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
HDFFNFJJ_03481 8.3e-99 padR K transcriptional
HDFFNFJJ_03482 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HDFFNFJJ_03483 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HDFFNFJJ_03484 2e-109 yfiR K Transcriptional regulator
HDFFNFJJ_03485 5.1e-221 yfiS EGP Major facilitator Superfamily
HDFFNFJJ_03486 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
HDFFNFJJ_03487 8.7e-287 yfiU EGP Major facilitator Superfamily
HDFFNFJJ_03488 3.1e-81 yfiV K transcriptional
HDFFNFJJ_03489 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDFFNFJJ_03490 6.2e-182 yfiY P ABC transporter substrate-binding protein
HDFFNFJJ_03491 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_03492 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_03493 1.8e-167 yfhB 5.3.3.17 S PhzF family
HDFFNFJJ_03494 3.9e-107 yfhC C nitroreductase
HDFFNFJJ_03495 2.1e-25 yfhD S YfhD-like protein
HDFFNFJJ_03497 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
HDFFNFJJ_03498 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HDFFNFJJ_03499 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HDFFNFJJ_03501 1.1e-209 yfhI EGP Major facilitator Superfamily
HDFFNFJJ_03502 6.2e-20 sspK S reproduction
HDFFNFJJ_03503 1.3e-44 yfhJ S WVELL protein
HDFFNFJJ_03504 9.2e-92 batE T Bacterial SH3 domain homologues
HDFFNFJJ_03505 3.5e-51 yfhL S SdpI/YhfL protein family
HDFFNFJJ_03506 6.7e-172 yfhM S Alpha beta hydrolase
HDFFNFJJ_03507 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDFFNFJJ_03508 0.0 yfhO S Bacterial membrane protein YfhO
HDFFNFJJ_03509 5.5e-186 yfhP S membrane-bound metal-dependent
HDFFNFJJ_03510 7.8e-212 mutY L A G-specific
HDFFNFJJ_03511 6.9e-36 yfhS
HDFFNFJJ_03512 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_03513 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HDFFNFJJ_03514 1.5e-37 ygaB S YgaB-like protein
HDFFNFJJ_03515 1.3e-104 ygaC J Belongs to the UPF0374 family
HDFFNFJJ_03516 1.8e-301 ygaD V ABC transporter
HDFFNFJJ_03517 8.7e-180 ygaE S Membrane
HDFFNFJJ_03518 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HDFFNFJJ_03519 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HDFFNFJJ_03520 4e-80 perR P Belongs to the Fur family
HDFFNFJJ_03521 1.5e-56 ygzB S UPF0295 protein
HDFFNFJJ_03522 6.7e-167 ygxA S Nucleotidyltransferase-like
HDFFNFJJ_03523 2.2e-96 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_03524 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HDFFNFJJ_03525 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
HDFFNFJJ_03526 2.3e-246 yoeA V MATE efflux family protein
HDFFNFJJ_03527 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HDFFNFJJ_03529 2.2e-96 L Integrase
HDFFNFJJ_03530 3e-34 yoeD G Helix-turn-helix domain
HDFFNFJJ_03531 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HDFFNFJJ_03532 2.5e-158 gltR1 K Transcriptional regulator
HDFFNFJJ_03533 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HDFFNFJJ_03534 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HDFFNFJJ_03535 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HDFFNFJJ_03536 7.8e-155 gltC K Transcriptional regulator
HDFFNFJJ_03537 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDFFNFJJ_03538 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDFFNFJJ_03539 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HDFFNFJJ_03540 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFFNFJJ_03541 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
HDFFNFJJ_03542 3.1e-144 yoxB
HDFFNFJJ_03543 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HDFFNFJJ_03544 6.2e-235 yoaB EGP Major facilitator Superfamily
HDFFNFJJ_03545 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HDFFNFJJ_03546 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFFNFJJ_03547 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDFFNFJJ_03548 1.9e-33 yoaF
HDFFNFJJ_03549 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HDFFNFJJ_03550 7e-14
HDFFNFJJ_03551 1.5e-38 S Protein of unknown function (DUF4025)
HDFFNFJJ_03552 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
HDFFNFJJ_03553 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HDFFNFJJ_03554 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HDFFNFJJ_03555 2.3e-111 yoaK S Membrane
HDFFNFJJ_03556 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HDFFNFJJ_03557 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HDFFNFJJ_03559 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
HDFFNFJJ_03561 1.5e-146 yoaP 3.1.3.18 K YoaP-like
HDFFNFJJ_03562 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HDFFNFJJ_03563 4.1e-89
HDFFNFJJ_03564 2.4e-172 yoaR V vancomycin resistance protein
HDFFNFJJ_03565 4.3e-75 yoaS S Protein of unknown function (DUF2975)
HDFFNFJJ_03566 4.2e-37 yozG K Transcriptional regulator
HDFFNFJJ_03567 1.1e-149 yoaT S Protein of unknown function (DUF817)
HDFFNFJJ_03568 8.6e-159 yoaU K LysR substrate binding domain
HDFFNFJJ_03569 6e-160 yijE EG EamA-like transporter family
HDFFNFJJ_03570 3.7e-78 yoaW
HDFFNFJJ_03571 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HDFFNFJJ_03572 2.3e-170 bla 3.5.2.6 V beta-lactamase
HDFFNFJJ_03576 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HDFFNFJJ_03577 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HDFFNFJJ_03578 1.4e-37 S TM2 domain
HDFFNFJJ_03579 5.7e-58 K Helix-turn-helix
HDFFNFJJ_03581 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
HDFFNFJJ_03582 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
HDFFNFJJ_03583 1.8e-178 yobF
HDFFNFJJ_03588 1.7e-207 S aspartate phosphatase
HDFFNFJJ_03590 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDFFNFJJ_03591 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDFFNFJJ_03592 2.6e-38 S YolD-like protein
HDFFNFJJ_03593 1.2e-49
HDFFNFJJ_03594 0.0 K Psort location Cytoplasmic, score
HDFFNFJJ_03595 2.7e-157 yobJ
HDFFNFJJ_03596 3e-86 S SMI1-KNR4 cell-wall
HDFFNFJJ_03597 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HDFFNFJJ_03598 7.9e-105 yokH G SMI1 / KNR4 family
HDFFNFJJ_03599 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HDFFNFJJ_03600 0.0 yobO M Pectate lyase superfamily protein
HDFFNFJJ_03601 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HDFFNFJJ_03602 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
HDFFNFJJ_03603 2.5e-143 yobR 2.3.1.1 J FR47-like protein
HDFFNFJJ_03604 3e-99 yobS K Transcriptional regulator
HDFFNFJJ_03605 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HDFFNFJJ_03606 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
HDFFNFJJ_03607 9e-178 yobV K WYL domain
HDFFNFJJ_03608 2.5e-95 yobW
HDFFNFJJ_03609 1e-51 czrA K transcriptional
HDFFNFJJ_03610 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HDFFNFJJ_03611 1.5e-92 yozB S membrane
HDFFNFJJ_03612 2.2e-145
HDFFNFJJ_03613 1.9e-94 yocC
HDFFNFJJ_03614 6.9e-189 yocD 3.4.17.13 V peptidase S66
HDFFNFJJ_03615 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HDFFNFJJ_03616 3.2e-198 desK 2.7.13.3 T Histidine kinase
HDFFNFJJ_03617 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDFFNFJJ_03618 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HDFFNFJJ_03619 0.0 recQ 3.6.4.12 L DNA helicase
HDFFNFJJ_03620 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDFFNFJJ_03621 3.3e-83 dksA T general stress protein
HDFFNFJJ_03622 6.4e-54 yocL
HDFFNFJJ_03623 6.6e-34
HDFFNFJJ_03624 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HDFFNFJJ_03625 1.1e-40 yozN
HDFFNFJJ_03626 1.9e-36 yocN
HDFFNFJJ_03627 4.2e-56 yozO S Bacterial PH domain
HDFFNFJJ_03628 2.7e-31 yozC
HDFFNFJJ_03629 5.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HDFFNFJJ_03630 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HDFFNFJJ_03631 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
HDFFNFJJ_03632 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HDFFNFJJ_03633 5.1e-168 yocS S -transporter
HDFFNFJJ_03634 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HDFFNFJJ_03635 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HDFFNFJJ_03636 0.0 yojO P Von Willebrand factor
HDFFNFJJ_03637 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HDFFNFJJ_03638 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HDFFNFJJ_03639 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HDFFNFJJ_03640 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HDFFNFJJ_03641 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDFFNFJJ_03643 4.2e-245 norM V Multidrug efflux pump
HDFFNFJJ_03644 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDFFNFJJ_03645 2.1e-125 yojG S deacetylase
HDFFNFJJ_03646 2.2e-60 yojF S Protein of unknown function (DUF1806)
HDFFNFJJ_03647 1.5e-43
HDFFNFJJ_03648 3.5e-163 rarD S -transporter
HDFFNFJJ_03649 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HDFFNFJJ_03650 3.4e-09
HDFFNFJJ_03651 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
HDFFNFJJ_03652 3.8e-66 yodA S tautomerase
HDFFNFJJ_03653 1.7e-57 yodB K transcriptional
HDFFNFJJ_03654 4.8e-108 yodC C nitroreductase
HDFFNFJJ_03655 3.8e-113 mhqD S Carboxylesterase
HDFFNFJJ_03656 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HDFFNFJJ_03657 6.2e-28 S Protein of unknown function (DUF3311)
HDFFNFJJ_03658 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDFFNFJJ_03659 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HDFFNFJJ_03660 1.7e-128 yodH Q Methyltransferase
HDFFNFJJ_03661 5.2e-24 yodI
HDFFNFJJ_03662 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HDFFNFJJ_03663 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HDFFNFJJ_03664 5.3e-09
HDFFNFJJ_03665 3.6e-54 yodL S YodL-like
HDFFNFJJ_03666 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HDFFNFJJ_03667 2.8e-24 yozD S YozD-like protein
HDFFNFJJ_03669 1.4e-124 yodN
HDFFNFJJ_03670 1.4e-36 yozE S Belongs to the UPF0346 family
HDFFNFJJ_03671 2.9e-47 yokU S YokU-like protein, putative antitoxin
HDFFNFJJ_03672 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HDFFNFJJ_03673 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HDFFNFJJ_03674 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HDFFNFJJ_03675 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HDFFNFJJ_03676 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HDFFNFJJ_03677 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDFFNFJJ_03680 2.9e-145 yiiD K acetyltransferase
HDFFNFJJ_03681 1e-256 cgeD M maturation of the outermost layer of the spore
HDFFNFJJ_03682 3.5e-38 cgeC
HDFFNFJJ_03683 1.2e-65 cgeA
HDFFNFJJ_03684 3.3e-188 cgeB S Spore maturation protein
HDFFNFJJ_03685 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HDFFNFJJ_03686 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
HDFFNFJJ_03688 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDFFNFJJ_03689 1.4e-10 K Cro/C1-type HTH DNA-binding domain
HDFFNFJJ_03697 1.9e-168 S Calcineurin-like phosphoesterase
HDFFNFJJ_03698 2.5e-30 sspB S spore protein
HDFFNFJJ_03703 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
HDFFNFJJ_03704 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HDFFNFJJ_03705 6.1e-38 O Glutaredoxin
HDFFNFJJ_03706 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFFNFJJ_03707 3.3e-97 L HNH endonuclease
HDFFNFJJ_03708 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFFNFJJ_03709 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFFNFJJ_03710 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFFNFJJ_03711 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HDFFNFJJ_03728 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HDFFNFJJ_03730 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HDFFNFJJ_03731 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HDFFNFJJ_03736 9.9e-115 DR0488 S protein conserved in bacteria
HDFFNFJJ_03737 0.0 2.7.7.7 L DNA polymerase
HDFFNFJJ_03738 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HDFFNFJJ_03739 1.2e-224 L DNA primase activity
HDFFNFJJ_03740 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
HDFFNFJJ_03741 1.4e-86
HDFFNFJJ_03742 7.6e-180 L AAA domain
HDFFNFJJ_03743 1.3e-170
HDFFNFJJ_03748 0.0 M Parallel beta-helix repeats
HDFFNFJJ_03749 7.7e-149 S Pfam:DUF867
HDFFNFJJ_03752 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
HDFFNFJJ_03753 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HDFFNFJJ_03754 2.3e-77
HDFFNFJJ_03761 1e-44
HDFFNFJJ_03763 1.5e-97 S Protein of unknown function (DUF1273)
HDFFNFJJ_03765 3e-78 yoqH M LysM domain
HDFFNFJJ_03768 8.8e-12 S Protein of unknown function (DUF2815)
HDFFNFJJ_03769 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
HDFFNFJJ_03780 1.1e-33 K Transcriptional regulator
HDFFNFJJ_03781 2.1e-177
HDFFNFJJ_03782 6e-263 S DNA-sulfur modification-associated
HDFFNFJJ_03783 6.8e-198 L Belongs to the 'phage' integrase family
HDFFNFJJ_03788 6.6e-106
HDFFNFJJ_03790 1.2e-86
HDFFNFJJ_03791 1.1e-96 S Super-infection exclusion protein B
HDFFNFJJ_03796 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
HDFFNFJJ_03797 3.8e-259
HDFFNFJJ_03798 4.6e-35 K Cro/C1-type HTH DNA-binding domain
HDFFNFJJ_03799 1.4e-256
HDFFNFJJ_03801 5.9e-238
HDFFNFJJ_03803 4e-17
HDFFNFJJ_03804 5.7e-55 bldD K domain, Protein
HDFFNFJJ_03807 0.0
HDFFNFJJ_03808 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDFFNFJJ_03810 2.6e-230
HDFFNFJJ_03813 1.8e-175
HDFFNFJJ_03814 0.0 gp17a S Terminase-like family
HDFFNFJJ_03815 6.3e-282
HDFFNFJJ_03816 2.1e-266
HDFFNFJJ_03817 1.6e-94
HDFFNFJJ_03818 5.7e-186
HDFFNFJJ_03819 5.1e-81
HDFFNFJJ_03820 1.1e-68
HDFFNFJJ_03822 1.4e-121
HDFFNFJJ_03823 2.6e-91
HDFFNFJJ_03824 8.1e-131
HDFFNFJJ_03825 1.6e-90
HDFFNFJJ_03828 1e-57
HDFFNFJJ_03829 1.1e-172
HDFFNFJJ_03830 8.1e-07
HDFFNFJJ_03831 2.5e-10 xkdX
HDFFNFJJ_03832 2.5e-86
HDFFNFJJ_03833 6.3e-70
HDFFNFJJ_03834 2.1e-193 xerH A Belongs to the 'phage' integrase family
HDFFNFJJ_03837 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HDFFNFJJ_03839 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
HDFFNFJJ_03840 2.2e-142 ybbA S Putative esterase
HDFFNFJJ_03841 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_03842 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_03843 7.2e-167 feuA P Iron-uptake system-binding protein
HDFFNFJJ_03844 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HDFFNFJJ_03845 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
HDFFNFJJ_03846 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HDFFNFJJ_03847 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HDFFNFJJ_03848 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFFNFJJ_03849 1.1e-150 ybbH K transcriptional
HDFFNFJJ_03850 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDFFNFJJ_03851 6.4e-87 ybbJ J acetyltransferase
HDFFNFJJ_03852 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HDFFNFJJ_03858 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_03859 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HDFFNFJJ_03860 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDFFNFJJ_03861 3e-225 ybbR S protein conserved in bacteria
HDFFNFJJ_03862 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDFFNFJJ_03863 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDFFNFJJ_03864 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HDFFNFJJ_03865 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
HDFFNFJJ_03866 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDFFNFJJ_03867 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HDFFNFJJ_03868 0.0 ybcC S Belongs to the UPF0753 family
HDFFNFJJ_03869 3.7e-96 can 4.2.1.1 P carbonic anhydrase
HDFFNFJJ_03870 3.9e-47
HDFFNFJJ_03871 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HDFFNFJJ_03872 5.1e-50 ybzH K Helix-turn-helix domain
HDFFNFJJ_03873 2e-203 ybcL EGP Major facilitator Superfamily
HDFFNFJJ_03875 9.1e-239 J 4Fe-4S single cluster domain
HDFFNFJJ_03876 1.6e-277 V CAAX protease self-immunity
HDFFNFJJ_03877 1.9e-135 skfE V ABC transporter
HDFFNFJJ_03878 4e-248 skfF S ABC transporter
HDFFNFJJ_03879 7.8e-91 C HEAT repeats
HDFFNFJJ_03880 9.6e-79 txn CO Thioredoxin-like
HDFFNFJJ_03881 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDFFNFJJ_03882 1.5e-123 T Transcriptional regulatory protein, C terminal
HDFFNFJJ_03883 1.8e-173 T His Kinase A (phospho-acceptor) domain
HDFFNFJJ_03885 1.6e-140 KLT Protein tyrosine kinase
HDFFNFJJ_03886 4.8e-154 ybdN
HDFFNFJJ_03887 1.5e-217 ybdO S Domain of unknown function (DUF4885)
HDFFNFJJ_03888 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HDFFNFJJ_03889 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HDFFNFJJ_03890 4.9e-30 ybxH S Family of unknown function (DUF5370)
HDFFNFJJ_03891 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
HDFFNFJJ_03892 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HDFFNFJJ_03893 4.9e-41 ybyB
HDFFNFJJ_03894 1.8e-290 ybeC E amino acid
HDFFNFJJ_03895 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDFFNFJJ_03896 7.3e-258 glpT G -transporter
HDFFNFJJ_03897 2.9e-35 S Protein of unknown function (DUF2651)
HDFFNFJJ_03898 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
HDFFNFJJ_03899 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HDFFNFJJ_03901 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HDFFNFJJ_03902 8.8e-162 ybfH EG EamA-like transporter family
HDFFNFJJ_03903 2.3e-145 msmR K AraC-like ligand binding domain
HDFFNFJJ_03904 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDFFNFJJ_03905 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HDFFNFJJ_03907 2.5e-169 S Alpha/beta hydrolase family
HDFFNFJJ_03908 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDFFNFJJ_03909 2.7e-85 ybfM S SNARE associated Golgi protein
HDFFNFJJ_03910 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HDFFNFJJ_03911 3.2e-46 ybfN
HDFFNFJJ_03912 3.6e-257 S Erythromycin esterase
HDFFNFJJ_03913 6.7e-167 ybfP K Transcriptional regulator
HDFFNFJJ_03914 3.9e-192 yceA S Belongs to the UPF0176 family
HDFFNFJJ_03915 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDFFNFJJ_03916 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFFNFJJ_03917 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDFFNFJJ_03918 4.9e-128 K UTRA
HDFFNFJJ_03920 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HDFFNFJJ_03921 6.7e-262 mmuP E amino acid
HDFFNFJJ_03922 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HDFFNFJJ_03923 2.3e-257 agcS E Sodium alanine symporter
HDFFNFJJ_03924 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
HDFFNFJJ_03925 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
HDFFNFJJ_03926 9e-170 glnL T Regulator
HDFFNFJJ_03927 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HDFFNFJJ_03928 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDFFNFJJ_03929 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HDFFNFJJ_03930 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HDFFNFJJ_03931 1.5e-124 ycbG K FCD
HDFFNFJJ_03932 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
HDFFNFJJ_03933 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
HDFFNFJJ_03934 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HDFFNFJJ_03935 7.3e-172 eamA1 EG spore germination
HDFFNFJJ_03936 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_03937 2.4e-170 T PhoQ Sensor
HDFFNFJJ_03938 4.8e-168 ycbN V ABC transporter, ATP-binding protein
HDFFNFJJ_03939 2.1e-115 S ABC-2 family transporter protein
HDFFNFJJ_03940 8.2e-53 ycbP S Protein of unknown function (DUF2512)
HDFFNFJJ_03941 1.3e-78 sleB 3.5.1.28 M Cell wall
HDFFNFJJ_03942 6.6e-136 ycbR T vWA found in TerF C terminus
HDFFNFJJ_03943 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HDFFNFJJ_03944 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HDFFNFJJ_03945 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDFFNFJJ_03946 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HDFFNFJJ_03947 6.2e-210 ycbU E Selenocysteine lyase
HDFFNFJJ_03948 5.8e-229 lmrB EGP the major facilitator superfamily
HDFFNFJJ_03949 4.8e-102 yxaF K Transcriptional regulator
HDFFNFJJ_03950 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HDFFNFJJ_03951 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HDFFNFJJ_03952 2e-59 S RDD family
HDFFNFJJ_03953 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
HDFFNFJJ_03954 2e-161 2.7.13.3 T GHKL domain
HDFFNFJJ_03955 1.2e-126 lytR_2 T LytTr DNA-binding domain
HDFFNFJJ_03956 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HDFFNFJJ_03957 4.5e-203 natB CP ABC-2 family transporter protein
HDFFNFJJ_03958 1.6e-174 yccK C Aldo keto reductase
HDFFNFJJ_03959 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HDFFNFJJ_03960 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_03961 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HDFFNFJJ_03962 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
HDFFNFJJ_03963 5.5e-174 S response regulator aspartate phosphatase
HDFFNFJJ_03964 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
HDFFNFJJ_03965 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HDFFNFJJ_03966 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HDFFNFJJ_03967 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HDFFNFJJ_03968 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HDFFNFJJ_03969 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDFFNFJJ_03970 7.3e-56 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HDFFNFJJ_03971 8.7e-40 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HDFFNFJJ_03972 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HDFFNFJJ_03973 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HDFFNFJJ_03974 6.3e-137 terC P Protein of unknown function (DUF475)
HDFFNFJJ_03975 0.0 yceG S Putative component of 'biosynthetic module'
HDFFNFJJ_03976 2e-192 yceH P Belongs to the TelA family
HDFFNFJJ_03977 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
HDFFNFJJ_03978 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
HDFFNFJJ_03979 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDFFNFJJ_03980 5.1e-229 proV 3.6.3.32 E glycine betaine
HDFFNFJJ_03981 1.3e-127 opuAB P glycine betaine
HDFFNFJJ_03982 5.3e-164 opuAC E glycine betaine
HDFFNFJJ_03983 1.2e-219 amhX S amidohydrolase
HDFFNFJJ_03984 1e-257 ycgA S Membrane
HDFFNFJJ_03985 1.1e-98 ycgB
HDFFNFJJ_03986 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HDFFNFJJ_03987 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDFFNFJJ_03988 6.5e-293 lctP C L-lactate permease
HDFFNFJJ_03989 6.2e-269 mdr EGP Major facilitator Superfamily
HDFFNFJJ_03990 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_03991 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HDFFNFJJ_03992 1.2e-151 yqcI S YqcI/YcgG family
HDFFNFJJ_03993 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HDFFNFJJ_03994 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HDFFNFJJ_03995 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDFFNFJJ_03996 2.5e-109 tmrB S AAA domain
HDFFNFJJ_03997 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDFFNFJJ_03998 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
HDFFNFJJ_03999 2.2e-179 oxyR3 K LysR substrate binding domain
HDFFNFJJ_04000 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HDFFNFJJ_04001 2.9e-145 ycgL S Predicted nucleotidyltransferase
HDFFNFJJ_04002 5.1e-170 ycgM E Proline dehydrogenase
HDFFNFJJ_04003 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HDFFNFJJ_04004 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDFFNFJJ_04005 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HDFFNFJJ_04006 2.6e-147 ycgQ S membrane
HDFFNFJJ_04007 1.2e-139 ycgR S permeases
HDFFNFJJ_04008 5.7e-163 I alpha/beta hydrolase fold
HDFFNFJJ_04009 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HDFFNFJJ_04010 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HDFFNFJJ_04011 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HDFFNFJJ_04012 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HDFFNFJJ_04013 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDFFNFJJ_04014 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HDFFNFJJ_04015 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
HDFFNFJJ_04016 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HDFFNFJJ_04017 5.5e-109 yciB M ErfK YbiS YcfS YnhG
HDFFNFJJ_04018 1.4e-228 yciC S GTPases (G3E family)
HDFFNFJJ_04019 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HDFFNFJJ_04020 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HDFFNFJJ_04023 3.3e-77 yckC S membrane
HDFFNFJJ_04024 3.5e-52 yckD S Protein of unknown function (DUF2680)
HDFFNFJJ_04025 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFFNFJJ_04026 3.4e-70 nin S Competence protein J (ComJ)
HDFFNFJJ_04027 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
HDFFNFJJ_04028 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
HDFFNFJJ_04029 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HDFFNFJJ_04030 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HDFFNFJJ_04031 1.3e-63 hxlR K transcriptional
HDFFNFJJ_04032 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_04035 5e-227 ydeG EGP Major facilitator Superfamily
HDFFNFJJ_04036 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HDFFNFJJ_04037 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
HDFFNFJJ_04038 3.9e-78 lrpB K transcriptional
HDFFNFJJ_04039 2.4e-71 lrpA K transcriptional
HDFFNFJJ_04040 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDFFNFJJ_04041 3.4e-161
HDFFNFJJ_04043 1.4e-74 S response regulator aspartate phosphatase
HDFFNFJJ_04044 9.5e-128 S TIR domain
HDFFNFJJ_04045 4.1e-65 S Domain of unknown function with cystatin-like fold (DUF4467)
HDFFNFJJ_04046 8.7e-87 yddI
HDFFNFJJ_04047 2.4e-189 yddH CBM50 M Lysozyme-like
HDFFNFJJ_04048 0.0 yddG S maturation of SSU-rRNA
HDFFNFJJ_04049 2e-55 S Domain of unknown function (DUF1874)
HDFFNFJJ_04050 0.0 yddE S AAA-like domain
HDFFNFJJ_04051 2.4e-95 yddD S TcpE family
HDFFNFJJ_04052 3e-40 yddC
HDFFNFJJ_04053 1.5e-173 yddB S Conjugative transposon protein TcpC
HDFFNFJJ_04054 1.2e-32 yddA
HDFFNFJJ_04057 1.5e-205 nicK L Replication initiation factor
HDFFNFJJ_04058 1e-273 ydcQ D Ftsk spoiiie family protein
HDFFNFJJ_04059 5.1e-63 S Bacterial protein of unknown function (DUF961)
HDFFNFJJ_04061 8.3e-41
HDFFNFJJ_04062 1.1e-16
HDFFNFJJ_04063 4.3e-62 yvaO K Transcriptional
HDFFNFJJ_04064 1.3e-90 immA E IrrE N-terminal-like domain
HDFFNFJJ_04065 1.9e-211 L Belongs to the 'phage' integrase family
HDFFNFJJ_04073 1.6e-84 ydcK S Belongs to the SprT family
HDFFNFJJ_04074 0.0 yhgF K COG2183 Transcriptional accessory protein
HDFFNFJJ_04075 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_04076 1.5e-82 ydcG S EVE domain
HDFFNFJJ_04080 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HDFFNFJJ_04081 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDFFNFJJ_04082 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HDFFNFJJ_04083 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HDFFNFJJ_04084 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HDFFNFJJ_04085 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HDFFNFJJ_04086 5.2e-57 rsbS T antagonist
HDFFNFJJ_04087 1.3e-143 rsbR T Positive regulator of sigma-B
HDFFNFJJ_04088 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HDFFNFJJ_04089 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HDFFNFJJ_04090 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDFFNFJJ_04091 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HDFFNFJJ_04092 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDFFNFJJ_04093 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HDFFNFJJ_04094 2.2e-263 ydbT S Membrane
HDFFNFJJ_04095 2.1e-82 ydbS S Bacterial PH domain
HDFFNFJJ_04096 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDFFNFJJ_04097 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDFFNFJJ_04098 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDFFNFJJ_04099 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDFFNFJJ_04100 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDFFNFJJ_04101 2.2e-07 S Fur-regulated basic protein A
HDFFNFJJ_04102 1.1e-18 S Fur-regulated basic protein B
HDFFNFJJ_04103 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HDFFNFJJ_04104 2.7e-52 ydbL
HDFFNFJJ_04105 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HDFFNFJJ_04106 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
HDFFNFJJ_04107 4.4e-181 ydbI S AI-2E family transporter
HDFFNFJJ_04108 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDFFNFJJ_04109 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HDFFNFJJ_04110 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HDFFNFJJ_04111 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HDFFNFJJ_04112 3.2e-155 ydbD P Catalase
HDFFNFJJ_04113 2.8e-63 ydbC S Domain of unknown function (DUF4937
HDFFNFJJ_04114 8.9e-59 ydbB G Cupin domain
HDFFNFJJ_04116 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HDFFNFJJ_04117 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HDFFNFJJ_04119 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HDFFNFJJ_04120 9.4e-40
HDFFNFJJ_04121 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDFFNFJJ_04122 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HDFFNFJJ_04123 0.0 ydaO E amino acid
HDFFNFJJ_04124 0.0 ydaN S Bacterial cellulose synthase subunit
HDFFNFJJ_04125 4.5e-233 ydaM M Glycosyl transferase family group 2
HDFFNFJJ_04126 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HDFFNFJJ_04127 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
HDFFNFJJ_04128 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HDFFNFJJ_04129 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDFFNFJJ_04130 2.5e-74 lrpC K Transcriptional regulator
HDFFNFJJ_04131 5.1e-47 ydzA EGP Major facilitator Superfamily
HDFFNFJJ_04132 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HDFFNFJJ_04133 6.8e-77 ydaG 1.4.3.5 S general stress protein
HDFFNFJJ_04134 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HDFFNFJJ_04135 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HDFFNFJJ_04136 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_04137 1.1e-99 ydaC Q Methyltransferase domain
HDFFNFJJ_04138 1.4e-294 ydaB IQ acyl-CoA ligase
HDFFNFJJ_04139 0.0 mtlR K transcriptional regulator, MtlR
HDFFNFJJ_04140 2.8e-176 ydhF S Oxidoreductase
HDFFNFJJ_04141 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HDFFNFJJ_04142 1.4e-49 yczJ S biosynthesis
HDFFNFJJ_04144 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
HDFFNFJJ_04145 1.2e-132 kipR K Transcriptional regulator
HDFFNFJJ_04146 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HDFFNFJJ_04147 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HDFFNFJJ_04148 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HDFFNFJJ_04149 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HDFFNFJJ_04150 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
HDFFNFJJ_04151 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HDFFNFJJ_04153 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HDFFNFJJ_04154 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HDFFNFJJ_04155 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HDFFNFJJ_04156 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HDFFNFJJ_04157 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HDFFNFJJ_04158 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HDFFNFJJ_04159 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HDFFNFJJ_04160 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HDFFNFJJ_04161 7.3e-56
HDFFNFJJ_04162 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HDFFNFJJ_04163 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HDFFNFJJ_04164 1.3e-100 ycnI S protein conserved in bacteria
HDFFNFJJ_04165 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDFFNFJJ_04166 6.1e-149 glcU U Glucose uptake
HDFFNFJJ_04167 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDFFNFJJ_04168 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDFFNFJJ_04169 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDFFNFJJ_04170 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HDFFNFJJ_04171 1.6e-45 ycnE S Monooxygenase
HDFFNFJJ_04172 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HDFFNFJJ_04173 6.5e-154 ycnC K Transcriptional regulator
HDFFNFJJ_04174 1.4e-251 ycnB EGP Major facilitator Superfamily
HDFFNFJJ_04175 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HDFFNFJJ_04176 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HDFFNFJJ_04177 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_04178 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDFFNFJJ_04179 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
HDFFNFJJ_04182 5.2e-71 S aspartate phosphatase
HDFFNFJJ_04183 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HDFFNFJJ_04184 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDFFNFJJ_04185 1.7e-204 yclI V ABC transporter (permease) YclI
HDFFNFJJ_04186 3.9e-122 yclH P ABC transporter
HDFFNFJJ_04187 9.9e-200 gerKB F Spore germination protein
HDFFNFJJ_04188 1.3e-232 gerKC S spore germination
HDFFNFJJ_04189 6.8e-282 gerKA EG Spore germination protein
HDFFNFJJ_04191 2.9e-310 yclG M Pectate lyase superfamily protein
HDFFNFJJ_04192 1.5e-267 dtpT E amino acid peptide transporter
HDFFNFJJ_04193 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
HDFFNFJJ_04194 1.1e-83 yclD
HDFFNFJJ_04195 4e-39 bsdD 4.1.1.61 S response to toxic substance
HDFFNFJJ_04196 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HDFFNFJJ_04197 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDFFNFJJ_04198 4.9e-162 bsdA K LysR substrate binding domain
HDFFNFJJ_04199 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HDFFNFJJ_04200 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HDFFNFJJ_04201 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HDFFNFJJ_04202 4.4e-115 yczE S membrane
HDFFNFJJ_04203 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HDFFNFJJ_04204 4.4e-255 ycxD K GntR family transcriptional regulator
HDFFNFJJ_04205 7.4e-164 ycxC EG EamA-like transporter family
HDFFNFJJ_04206 4.9e-91 S YcxB-like protein
HDFFNFJJ_04207 4.2e-228 EGP Major Facilitator Superfamily
HDFFNFJJ_04208 5.7e-140 srfAD Q thioesterase
HDFFNFJJ_04209 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HDFFNFJJ_04210 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFFNFJJ_04211 1.5e-20 L COG3666 Transposase and inactivated derivatives
HDFFNFJJ_04212 6e-128
HDFFNFJJ_04214 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDFFNFJJ_04220 3.4e-57 traC L Domain of unknown function (DUF1738)
HDFFNFJJ_04221 7e-148 S DNA gyrase/topoisomerase IV, subunit A
HDFFNFJJ_04222 2.6e-184 S DNA gyrase B
HDFFNFJJ_04223 4e-15 repA S Replication initiator protein A (RepA) N-terminus
HDFFNFJJ_04225 9.1e-11 tdk 2.7.1.21 F Psort location Cytoplasmic, score
HDFFNFJJ_04231 1.6e-17 S Endodeoxyribonuclease RusA
HDFFNFJJ_04232 1.8e-21 2.7.4.8 F Guanylate kinase homologues.
HDFFNFJJ_04236 0.0 S Bacterial DNA polymerase III alpha subunit
HDFFNFJJ_04238 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HDFFNFJJ_04240 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDFFNFJJ_04243 1.3e-06 yfbR S HD containing hydrolase-like enzyme
HDFFNFJJ_04245 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HDFFNFJJ_04246 2.4e-15 K Transcriptional regulator
HDFFNFJJ_04247 1.4e-86 S exonuclease activity
HDFFNFJJ_04249 1e-89 S DNA primase activity
HDFFNFJJ_04250 6.1e-110 S DNA helicase activity
HDFFNFJJ_04251 1.3e-15
HDFFNFJJ_04252 1.5e-24
HDFFNFJJ_04254 4e-39
HDFFNFJJ_04256 1.5e-11 fld C Flavodoxin
HDFFNFJJ_04257 4.3e-104 S Ribonucleotide reductase, small chain
HDFFNFJJ_04258 3.3e-277 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
HDFFNFJJ_04259 1.9e-64 S AAA domain
HDFFNFJJ_04262 8.2e-48 F Nucleoside 2-deoxyribosyltransferase
HDFFNFJJ_04263 2.5e-34
HDFFNFJJ_04265 2e-07
HDFFNFJJ_04266 1.5e-31 yxcD S Protein of unknown function (DUF2653)
HDFFNFJJ_04268 8.1e-20
HDFFNFJJ_04269 2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
HDFFNFJJ_04272 2.9e-52
HDFFNFJJ_04273 3.6e-73 L integrase family
HDFFNFJJ_04276 1.6e-22 yocH 3.5.1.28 M 3D domain
HDFFNFJJ_04277 1.2e-68 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
HDFFNFJJ_04279 9.7e-83
HDFFNFJJ_04281 1.9e-177 S response regulator aspartate phosphatase
HDFFNFJJ_04284 8.1e-29 S Phage terminase, small subunit
HDFFNFJJ_04287 1.6e-106 S Phage portal protein
HDFFNFJJ_04288 1.9e-55 S Caudovirus prohead serine protease
HDFFNFJJ_04289 6.8e-87 S Phage capsid family
HDFFNFJJ_04291 1.4e-21 S DNA packaging
HDFFNFJJ_04292 1.2e-10 S Phage head-tail joining protein
HDFFNFJJ_04293 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
HDFFNFJJ_04294 2.5e-07
HDFFNFJJ_04295 1.6e-40 S Phage tail tube protein
HDFFNFJJ_04297 2.3e-174 D Phage tail tape measure protein
HDFFNFJJ_04298 1e-176 S Phage tail protein
HDFFNFJJ_04299 2.4e-147 S Phage minor structural protein
HDFFNFJJ_04300 1.1e-23
HDFFNFJJ_04301 4.6e-76 S N-acetylmuramoyl-L-alanine amidase activity
HDFFNFJJ_04302 3e-12
HDFFNFJJ_04305 4.3e-09 S SPP1 phage holin
HDFFNFJJ_04306 4.4e-106 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
HDFFNFJJ_04307 1.2e-97 S Phage integrase family
HDFFNFJJ_04308 4.6e-174 A Pre-toxin TG
HDFFNFJJ_04309 1.5e-63 S Immunity protein 70
HDFFNFJJ_04311 2.7e-61
HDFFNFJJ_04314 1.1e-16 ydhU P Manganese containing catalase
HDFFNFJJ_04315 8.7e-78 ydhU P Catalase
HDFFNFJJ_04316 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HDFFNFJJ_04317 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDFFNFJJ_04318 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HDFFNFJJ_04319 3.9e-133 ydhQ K UTRA
HDFFNFJJ_04320 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFFNFJJ_04321 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDFFNFJJ_04322 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HDFFNFJJ_04323 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HDFFNFJJ_04324 4.6e-200 pbuE EGP Major facilitator Superfamily
HDFFNFJJ_04325 1.7e-99 ydhK M Protein of unknown function (DUF1541)
HDFFNFJJ_04326 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDFFNFJJ_04327 4.1e-86 K Acetyltransferase (GNAT) domain
HDFFNFJJ_04329 4.6e-69 frataxin S Domain of unknown function (DU1801)
HDFFNFJJ_04330 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HDFFNFJJ_04331 1.9e-127
HDFFNFJJ_04332 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HDFFNFJJ_04333 3.3e-244 ydhD M Glycosyl hydrolase
HDFFNFJJ_04334 6.5e-122 ydhC K FCD
HDFFNFJJ_04335 1.2e-121 ydhB S membrane transporter protein
HDFFNFJJ_04336 2.5e-209 tcaB EGP Major facilitator Superfamily
HDFFNFJJ_04337 1.1e-69 ydgJ K Winged helix DNA-binding domain
HDFFNFJJ_04338 1e-113 drgA C nitroreductase
HDFFNFJJ_04339 0.0 ydgH S drug exporters of the RND superfamily
HDFFNFJJ_04340 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HDFFNFJJ_04341 4.6e-91 dinB S DinB family
HDFFNFJJ_04342 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HDFFNFJJ_04343 4.2e-308 expZ S ABC transporter
HDFFNFJJ_04344 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
HDFFNFJJ_04345 1.9e-53 S DoxX-like family
HDFFNFJJ_04346 1.5e-101 K Bacterial regulatory proteins, tetR family
HDFFNFJJ_04347 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HDFFNFJJ_04348 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HDFFNFJJ_04349 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HDFFNFJJ_04350 5.2e-122 ydfS S Protein of unknown function (DUF421)
HDFFNFJJ_04351 4.4e-118 ydfR S Protein of unknown function (DUF421)
HDFFNFJJ_04353 6.3e-29
HDFFNFJJ_04354 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HDFFNFJJ_04355 1.3e-57 traF CO Thioredoxin
HDFFNFJJ_04356 8.8e-63 mhqP S DoxX
HDFFNFJJ_04357 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HDFFNFJJ_04358 9.6e-112 ydfN C nitroreductase
HDFFNFJJ_04359 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDFFNFJJ_04360 3.2e-147 K Bacterial transcription activator, effector binding domain
HDFFNFJJ_04361 5.9e-118 S Protein of unknown function (DUF554)
HDFFNFJJ_04362 1.9e-177 S Alpha/beta hydrolase family
HDFFNFJJ_04363 0.0 ydfJ S drug exporters of the RND superfamily
HDFFNFJJ_04364 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDFFNFJJ_04365 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
HDFFNFJJ_04367 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HDFFNFJJ_04368 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HDFFNFJJ_04369 5.9e-117 ydfE S Flavin reductase like domain
HDFFNFJJ_04370 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDFFNFJJ_04371 1e-162 ydfC EG EamA-like transporter family
HDFFNFJJ_04372 7.2e-149 ydfB J GNAT acetyltransferase
HDFFNFJJ_04373 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDFFNFJJ_04374 1.3e-57 arsR K transcriptional
HDFFNFJJ_04375 8.4e-105 ydeS K Transcriptional regulator
HDFFNFJJ_04376 1.2e-195 ydeR EGP Major facilitator Superfamily
HDFFNFJJ_04377 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HDFFNFJJ_04378 4.8e-69 ydeP K Transcriptional regulator
HDFFNFJJ_04379 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HDFFNFJJ_04380 1.1e-58 K HxlR-like helix-turn-helix
HDFFNFJJ_04381 8.6e-107 ydeN S Serine hydrolase
HDFFNFJJ_04382 4.2e-74 maoC I N-terminal half of MaoC dehydratase
HDFFNFJJ_04383 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDFFNFJJ_04384 1.8e-153 ydeK EG -transporter
HDFFNFJJ_04385 4e-116
HDFFNFJJ_04386 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HDFFNFJJ_04387 2.9e-47 ydeH
HDFFNFJJ_04388 3.4e-220 ydeG EGP Major facilitator superfamily
HDFFNFJJ_04389 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDFFNFJJ_04390 2.5e-166 ydeE K AraC family transcriptional regulator
HDFFNFJJ_04391 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDFFNFJJ_04392 1.1e-166 rhaS5 K AraC-like ligand binding domain
HDFFNFJJ_04393 4.6e-35 ydzE EG spore germination
HDFFNFJJ_04394 6.1e-79 carD K Transcription factor
HDFFNFJJ_04395 8.7e-30 cspL K Cold shock
HDFFNFJJ_04396 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)