ORF_ID e_value Gene_name EC_number CAZy COGs Description
KHDCFEJC_00001 1.3e-102 L Phage integrase family
KHDCFEJC_00002 1.2e-106 XK26_04895
KHDCFEJC_00003 5.3e-07
KHDCFEJC_00005 7.5e-29 yvbK 3.1.3.25 K GNAT family
KHDCFEJC_00006 7.7e-54 sip L Belongs to the 'phage' integrase family
KHDCFEJC_00007 1.1e-154 L Initiator Replication protein
KHDCFEJC_00008 8.8e-52
KHDCFEJC_00009 1e-50 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KHDCFEJC_00010 3.4e-40 S RelB antitoxin
KHDCFEJC_00011 4e-107 L Integrase
KHDCFEJC_00012 2e-27 S Protein of unknown function (DUF1093)
KHDCFEJC_00013 1.5e-27
KHDCFEJC_00015 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KHDCFEJC_00017 1.3e-150 yjjH S Calcineurin-like phosphoesterase
KHDCFEJC_00018 3e-252 dtpT U amino acid peptide transporter
KHDCFEJC_00021 2.3e-33 S Bacterial mobilisation protein (MobC)
KHDCFEJC_00022 3.6e-152 U Relaxase/Mobilisation nuclease domain
KHDCFEJC_00023 1.5e-42 S COG NOG38524 non supervised orthologous group
KHDCFEJC_00026 2.6e-79 L Phage integrase family
KHDCFEJC_00027 0.0 pacL 3.6.3.8 P P-type ATPase
KHDCFEJC_00028 1.3e-41
KHDCFEJC_00029 1.1e-44 repA S Replication initiator protein A
KHDCFEJC_00030 1.5e-185 U Relaxase/Mobilisation nuclease domain
KHDCFEJC_00031 2.3e-54 S Bacterial mobilisation protein (MobC)
KHDCFEJC_00033 0.0 ybfG M peptidoglycan-binding domain-containing protein
KHDCFEJC_00034 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KHDCFEJC_00035 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
KHDCFEJC_00036 2.3e-107 L Integrase
KHDCFEJC_00037 2.5e-29
KHDCFEJC_00038 2.9e-176 L Initiator Replication protein
KHDCFEJC_00039 2.8e-88
KHDCFEJC_00040 0.0 pepF E oligoendopeptidase F
KHDCFEJC_00041 5.8e-205 coiA 3.6.4.12 S Competence protein
KHDCFEJC_00042 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KHDCFEJC_00043 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KHDCFEJC_00044 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
KHDCFEJC_00045 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KHDCFEJC_00055 5.5e-08
KHDCFEJC_00065 1.3e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
KHDCFEJC_00066 4.2e-164 corA P CorA-like Mg2+ transporter protein
KHDCFEJC_00067 1.7e-36 K sequence-specific DNA binding
KHDCFEJC_00068 6.1e-45 S Phage derived protein Gp49-like (DUF891)
KHDCFEJC_00069 2e-106 L Integrase
KHDCFEJC_00070 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KHDCFEJC_00071 2.7e-58 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
KHDCFEJC_00072 1.2e-222 G Polysaccharide deacetylase
KHDCFEJC_00073 5.8e-161 L Initiator Replication protein
KHDCFEJC_00074 1.6e-28
KHDCFEJC_00075 1.4e-13 S Psort location CytoplasmicMembrane, score
KHDCFEJC_00076 2.4e-56 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KHDCFEJC_00077 1e-69
KHDCFEJC_00079 1.6e-28 M Glycosyl hydrolases family 25
KHDCFEJC_00080 4e-34 M Glycosyl hydrolases family 25
KHDCFEJC_00081 1.8e-72 K Transcriptional regulator
KHDCFEJC_00082 4.3e-121 K Bacterial regulatory proteins, tetR family
KHDCFEJC_00083 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
KHDCFEJC_00084 5.5e-118
KHDCFEJC_00085 5.2e-42
KHDCFEJC_00086 1e-40
KHDCFEJC_00087 8.2e-252 ydiC1 EGP Major facilitator Superfamily
KHDCFEJC_00088 9.5e-65 K helix_turn_helix, mercury resistance
KHDCFEJC_00089 4.6e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
KHDCFEJC_00090 4.8e-141 mtsB U ABC 3 transport family
KHDCFEJC_00091 1.3e-131 mntB 3.6.3.35 P ABC transporter
KHDCFEJC_00092 1.4e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KHDCFEJC_00093 3.5e-199 K Helix-turn-helix domain
KHDCFEJC_00094 1.3e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
KHDCFEJC_00095 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
KHDCFEJC_00096 2.6e-52 yitW S Iron-sulfur cluster assembly protein
KHDCFEJC_00097 1.6e-263 P Sodium:sulfate symporter transmembrane region
KHDCFEJC_00098 5.2e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHDCFEJC_00099 3.4e-183 aroF 2.5.1.54 E DAHP synthetase I family
KHDCFEJC_00100 9.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHDCFEJC_00101 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHDCFEJC_00102 5.2e-145 yddE S AAA-like domain
KHDCFEJC_00105 4.8e-30 yddG S maturation of SSU-rRNA
KHDCFEJC_00106 7.7e-40 yddH CBM50 M Lysozyme-like
KHDCFEJC_00110 8.4e-38
KHDCFEJC_00112 1e-58 S helicase activity
KHDCFEJC_00115 9.8e-14 S ABC-2 family transporter protein
KHDCFEJC_00116 2.9e-53 V ATPases associated with a variety of cellular activities
KHDCFEJC_00118 7.5e-08 S Bacteriocin class IIc cyclic gassericin A-like
KHDCFEJC_00120 6.4e-14 yddB S Conjugative transposon protein TcpC
KHDCFEJC_00124 3.8e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHDCFEJC_00125 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KHDCFEJC_00126 9.8e-82 ydcK S Belongs to the SprT family
KHDCFEJC_00127 0.0 yhgF K Tex-like protein N-terminal domain protein
KHDCFEJC_00128 7.5e-71
KHDCFEJC_00129 0.0 pacL 3.6.3.8 P P-type ATPase
KHDCFEJC_00130 1.4e-62 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KHDCFEJC_00131 7.6e-72 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KHDCFEJC_00132 3.4e-288 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHDCFEJC_00133 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KHDCFEJC_00134 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
KHDCFEJC_00135 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHDCFEJC_00136 1.1e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHDCFEJC_00137 1.6e-151 pnuC H nicotinamide mononucleotide transporter
KHDCFEJC_00138 4.7e-194 ybiR P Citrate transporter
KHDCFEJC_00139 7.8e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
KHDCFEJC_00140 2.5e-53 S Cupin domain
KHDCFEJC_00141 1.7e-48 5.3.3.19 S Cupin 2, conserved barrel domain protein
KHDCFEJC_00143 1.5e-52
KHDCFEJC_00144 3e-72
KHDCFEJC_00145 3e-131 1.5.1.39 C nitroreductase
KHDCFEJC_00146 6.9e-151 G Transmembrane secretion effector
KHDCFEJC_00147 7.5e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHDCFEJC_00148 7.8e-143
KHDCFEJC_00150 1.9e-71 spxA 1.20.4.1 P ArsC family
KHDCFEJC_00151 1.5e-33
KHDCFEJC_00152 2.5e-89 V VanZ like family
KHDCFEJC_00153 1.1e-240 EGP Major facilitator Superfamily
KHDCFEJC_00154 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KHDCFEJC_00155 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHDCFEJC_00156 7e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KHDCFEJC_00157 1.5e-152 licD M LicD family
KHDCFEJC_00158 1.3e-82 K Transcriptional regulator
KHDCFEJC_00159 1.5e-19
KHDCFEJC_00160 3e-225 pbuG S permease
KHDCFEJC_00161 1.2e-58 S Protein of unknown function (DUF1648)
KHDCFEJC_00163 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHDCFEJC_00164 1.1e-178 yneE K Transcriptional regulator
KHDCFEJC_00165 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KHDCFEJC_00166 5e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHDCFEJC_00167 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHDCFEJC_00168 4.4e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KHDCFEJC_00169 2.1e-126 IQ reductase
KHDCFEJC_00170 9.5e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KHDCFEJC_00171 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KHDCFEJC_00172 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KHDCFEJC_00173 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KHDCFEJC_00174 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHDCFEJC_00175 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KHDCFEJC_00176 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KHDCFEJC_00177 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KHDCFEJC_00178 4.1e-122 S Protein of unknown function (DUF554)
KHDCFEJC_00179 1.6e-160 K LysR substrate binding domain
KHDCFEJC_00180 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
KHDCFEJC_00181 4.2e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KHDCFEJC_00182 2.3e-93 K transcriptional regulator
KHDCFEJC_00183 7.5e-300 norB EGP Major Facilitator
KHDCFEJC_00184 1.2e-139 f42a O Band 7 protein
KHDCFEJC_00185 4.2e-53
KHDCFEJC_00186 1.3e-28
KHDCFEJC_00187 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KHDCFEJC_00188 1.8e-80 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
KHDCFEJC_00189 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
KHDCFEJC_00190 7.9e-41
KHDCFEJC_00191 0.0 S Pfam Methyltransferase
KHDCFEJC_00192 2.7e-129 N Cell shape-determining protein MreB
KHDCFEJC_00193 1.4e-278 bmr3 EGP Major facilitator Superfamily
KHDCFEJC_00194 3.5e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHDCFEJC_00195 1.6e-121
KHDCFEJC_00196 1.3e-290 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
KHDCFEJC_00197 1.2e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KHDCFEJC_00198 9.2e-256 mmuP E amino acid
KHDCFEJC_00199 9e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KHDCFEJC_00200 1.2e-231 mntH P H( )-stimulated, divalent metal cation uptake system
KHDCFEJC_00202 1.1e-155 T Calcineurin-like phosphoesterase superfamily domain
KHDCFEJC_00203 2e-94 K Acetyltransferase (GNAT) domain
KHDCFEJC_00204 3.8e-93
KHDCFEJC_00205 5.2e-182 P secondary active sulfate transmembrane transporter activity
KHDCFEJC_00206 1.4e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
KHDCFEJC_00212 5.1e-08
KHDCFEJC_00217 8.5e-118 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KHDCFEJC_00218 6e-140 K Helix-turn-helix domain
KHDCFEJC_00219 2.9e-38 S TfoX C-terminal domain
KHDCFEJC_00220 1e-81 hpk9 2.7.13.3 T GHKL domain
KHDCFEJC_00221 4.1e-137 hpk9 2.7.13.3 T GHKL domain
KHDCFEJC_00222 1.6e-261
KHDCFEJC_00223 1.3e-75
KHDCFEJC_00224 9.2e-187 S Cell surface protein
KHDCFEJC_00225 1.7e-101 S WxL domain surface cell wall-binding
KHDCFEJC_00226 1.7e-179 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
KHDCFEJC_00227 3.8e-69 S Iron-sulphur cluster biosynthesis
KHDCFEJC_00228 1e-27 S GyrI-like small molecule binding domain
KHDCFEJC_00229 1.9e-74 S GyrI-like small molecule binding domain
KHDCFEJC_00230 1.2e-186 S Cell surface protein
KHDCFEJC_00231 8.9e-101 S WxL domain surface cell wall-binding
KHDCFEJC_00232 9.4e-154 NU Mycoplasma protein of unknown function, DUF285
KHDCFEJC_00233 5.9e-117
KHDCFEJC_00234 4.4e-115 S Haloacid dehalogenase-like hydrolase
KHDCFEJC_00235 4.7e-57 K Transcriptional regulator PadR-like family
KHDCFEJC_00236 2.1e-120 M1-1017
KHDCFEJC_00237 2e-61 K Transcriptional regulator, HxlR family
KHDCFEJC_00238 3.9e-210 ytbD EGP Major facilitator Superfamily
KHDCFEJC_00239 1.4e-94 M ErfK YbiS YcfS YnhG
KHDCFEJC_00240 0.0 asnB 6.3.5.4 E Asparagine synthase
KHDCFEJC_00241 6.3e-134 K LytTr DNA-binding domain
KHDCFEJC_00242 3e-205 2.7.13.3 T GHKL domain
KHDCFEJC_00243 2.5e-159 EGP Major facilitator Superfamily
KHDCFEJC_00244 6.4e-173 ropB K Helix-turn-helix XRE-family like proteins
KHDCFEJC_00245 4.7e-176 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
KHDCFEJC_00246 2e-118 puuP_1 E Amino acid permease
KHDCFEJC_00247 1.2e-112 puuP_1 E Amino acid permease
KHDCFEJC_00248 3.2e-232 yxiO S Vacuole effluxer Atg22 like
KHDCFEJC_00249 1.7e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
KHDCFEJC_00250 2e-160 I alpha/beta hydrolase fold
KHDCFEJC_00251 4.8e-131 treR K UTRA
KHDCFEJC_00252 1.4e-238
KHDCFEJC_00253 5.6e-39 S Cytochrome B5
KHDCFEJC_00254 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHDCFEJC_00255 9e-217 2.7.7.65 T Diguanylate cyclase, GGDEF domain
KHDCFEJC_00256 6.8e-127 yliE T EAL domain
KHDCFEJC_00257 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHDCFEJC_00258 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KHDCFEJC_00259 2e-80
KHDCFEJC_00260 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHDCFEJC_00261 2.9e-190 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHDCFEJC_00262 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHDCFEJC_00263 4.9e-22
KHDCFEJC_00264 4.4e-79
KHDCFEJC_00265 2.2e-165 K LysR substrate binding domain
KHDCFEJC_00266 2.4e-243 P Sodium:sulfate symporter transmembrane region
KHDCFEJC_00267 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
KHDCFEJC_00268 1e-21
KHDCFEJC_00269 8.2e-34 K sequence-specific DNA binding
KHDCFEJC_00270 1.7e-191 EGP Major facilitator Superfamily
KHDCFEJC_00271 3.6e-88 niaR S 3H domain
KHDCFEJC_00272 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHDCFEJC_00273 1.3e-117 K Transcriptional regulator
KHDCFEJC_00274 3.2e-154 V ABC transporter
KHDCFEJC_00275 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
KHDCFEJC_00276 1.1e-245 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KHDCFEJC_00277 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_00278 8.6e-297 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_00279 5.1e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
KHDCFEJC_00280 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KHDCFEJC_00281 1.8e-130 gntR K UTRA
KHDCFEJC_00282 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
KHDCFEJC_00283 2.5e-121 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KHDCFEJC_00284 1.8e-81
KHDCFEJC_00285 9.8e-152 S hydrolase
KHDCFEJC_00286 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHDCFEJC_00287 8.3e-152 EG EamA-like transporter family
KHDCFEJC_00288 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KHDCFEJC_00289 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
KHDCFEJC_00290 1.9e-231
KHDCFEJC_00291 1.9e-77 fld C Flavodoxin
KHDCFEJC_00292 0.0 M Bacterial Ig-like domain (group 3)
KHDCFEJC_00293 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
KHDCFEJC_00294 2.7e-32
KHDCFEJC_00295 8.3e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
KHDCFEJC_00296 1.4e-267 ycaM E amino acid
KHDCFEJC_00297 3e-78 K Winged helix DNA-binding domain
KHDCFEJC_00298 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
KHDCFEJC_00299 5.7e-163 akr5f 1.1.1.346 S reductase
KHDCFEJC_00300 1.3e-162 K Transcriptional regulator
KHDCFEJC_00302 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KHDCFEJC_00303 3.2e-166 S Putative esterase
KHDCFEJC_00304 2.4e-130 gntR2 K Transcriptional regulator
KHDCFEJC_00305 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHDCFEJC_00306 8.9e-139
KHDCFEJC_00307 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHDCFEJC_00308 5.5e-138 rrp8 K LytTr DNA-binding domain
KHDCFEJC_00309 9.4e-92 M1-874 K Domain of unknown function (DUF1836)
KHDCFEJC_00310 1.7e-60
KHDCFEJC_00311 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
KHDCFEJC_00312 4.4e-58
KHDCFEJC_00314 5.5e-217 yhdP S Transporter associated domain
KHDCFEJC_00315 4.9e-87 nrdI F Belongs to the NrdI family
KHDCFEJC_00316 2.9e-269 yjcE P Sodium proton antiporter
KHDCFEJC_00317 2.8e-213 yttB EGP Major facilitator Superfamily
KHDCFEJC_00318 5e-63 K helix_turn_helix, mercury resistance
KHDCFEJC_00319 1.8e-173 C Zinc-binding dehydrogenase
KHDCFEJC_00320 8.5e-57 S SdpI/YhfL protein family
KHDCFEJC_00321 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHDCFEJC_00322 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
KHDCFEJC_00323 5e-218 patA 2.6.1.1 E Aminotransferase
KHDCFEJC_00324 1.9e-158 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHDCFEJC_00325 3e-18
KHDCFEJC_00326 1.7e-126 S membrane transporter protein
KHDCFEJC_00327 1.5e-30 mleR K LysR family
KHDCFEJC_00328 6.9e-53 mleR K LysR family
KHDCFEJC_00329 5.6e-115 ylbE GM NAD(P)H-binding
KHDCFEJC_00330 8.2e-96 wecD K Acetyltransferase (GNAT) family
KHDCFEJC_00331 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KHDCFEJC_00332 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KHDCFEJC_00333 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
KHDCFEJC_00334 6.2e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHDCFEJC_00335 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KHDCFEJC_00336 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHDCFEJC_00337 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KHDCFEJC_00338 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHDCFEJC_00339 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHDCFEJC_00340 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KHDCFEJC_00341 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHDCFEJC_00342 1e-298 pucR QT Purine catabolism regulatory protein-like family
KHDCFEJC_00343 3.5e-236 pbuX F xanthine permease
KHDCFEJC_00344 2.4e-221 pbuG S Permease family
KHDCFEJC_00345 5.6e-161 GM NmrA-like family
KHDCFEJC_00346 6.5e-156 T EAL domain
KHDCFEJC_00347 2.6e-94
KHDCFEJC_00348 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHDCFEJC_00349 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
KHDCFEJC_00350 5.4e-228 patA 2.6.1.1 E Aminotransferase
KHDCFEJC_00351 9.5e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KHDCFEJC_00352 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHDCFEJC_00353 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
KHDCFEJC_00354 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KHDCFEJC_00355 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHDCFEJC_00356 2.7e-39 ptsH G phosphocarrier protein HPR
KHDCFEJC_00357 6.5e-30
KHDCFEJC_00358 0.0 clpE O Belongs to the ClpA ClpB family
KHDCFEJC_00359 8.2e-102 L Integrase
KHDCFEJC_00360 1e-63 K Winged helix DNA-binding domain
KHDCFEJC_00361 4e-181 oppF P Belongs to the ABC transporter superfamily
KHDCFEJC_00362 9.2e-203 oppD P Belongs to the ABC transporter superfamily
KHDCFEJC_00363 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHDCFEJC_00364 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHDCFEJC_00365 1.3e-309 oppA E ABC transporter, substratebinding protein
KHDCFEJC_00366 3.2e-57 ywjH S Protein of unknown function (DUF1634)
KHDCFEJC_00367 5.5e-126 yxaA S membrane transporter protein
KHDCFEJC_00368 4.6e-160 lysR5 K LysR substrate binding domain
KHDCFEJC_00369 6.5e-198 M MucBP domain
KHDCFEJC_00370 7.8e-274
KHDCFEJC_00371 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHDCFEJC_00372 1.4e-253 gor 1.8.1.7 C Glutathione reductase
KHDCFEJC_00373 8.6e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
KHDCFEJC_00374 9.7e-291 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KHDCFEJC_00375 9.5e-213 gntP EG Gluconate
KHDCFEJC_00376 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
KHDCFEJC_00377 9.3e-188 yueF S AI-2E family transporter
KHDCFEJC_00378 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KHDCFEJC_00379 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
KHDCFEJC_00380 7.8e-48 K sequence-specific DNA binding
KHDCFEJC_00381 1.3e-134 cwlO M NlpC/P60 family
KHDCFEJC_00382 4.1e-106 ygaC J Belongs to the UPF0374 family
KHDCFEJC_00383 1.1e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
KHDCFEJC_00384 4.3e-124
KHDCFEJC_00385 6.8e-101 K DNA-templated transcription, initiation
KHDCFEJC_00386 1e-27
KHDCFEJC_00387 7e-30
KHDCFEJC_00388 7.3e-33 S Protein of unknown function (DUF2922)
KHDCFEJC_00389 3.8e-53
KHDCFEJC_00390 3.5e-94 rfbP M Bacterial sugar transferase
KHDCFEJC_00391 1.3e-241 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
KHDCFEJC_00392 2e-146 cps1D M Domain of unknown function (DUF4422)
KHDCFEJC_00393 3.3e-200 cps3I G Acyltransferase family
KHDCFEJC_00394 1.1e-65 L Transposase DDE domain
KHDCFEJC_00395 2.1e-66 L Putative transposase of IS4/5 family (DUF4096)
KHDCFEJC_00396 1.3e-117
KHDCFEJC_00397 1.4e-35 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHDCFEJC_00398 1.6e-68 wcmJ S SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
KHDCFEJC_00399 5.9e-85 cps2J S Polysaccharide biosynthesis protein
KHDCFEJC_00400 3.5e-26 M -O-antigen
KHDCFEJC_00401 9.1e-13 M -O-antigen
KHDCFEJC_00402 1.8e-60 GT4 M Glycosyl transferases group 1
KHDCFEJC_00403 1.1e-86 GT4 M Glycosyltransferase Family 4
KHDCFEJC_00404 2.9e-75 tagA 2.4.1.187 GT26 M Belongs to the glycosyltransferase 26 family
KHDCFEJC_00405 3.1e-27 D protein tyrosine kinase activity
KHDCFEJC_00406 6.8e-36 wcoI 2.7.10.1, 2.7.10.2 M biosynthesis protein
KHDCFEJC_00407 2.8e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHDCFEJC_00408 1.9e-159 yihY S Belongs to the UPF0761 family
KHDCFEJC_00409 2.5e-203 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KHDCFEJC_00410 4.5e-211 pbpX1 V Beta-lactamase
KHDCFEJC_00411 1.2e-252 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KHDCFEJC_00412 1.4e-158 L hmm pf00665
KHDCFEJC_00413 3.6e-131 L Helix-turn-helix domain
KHDCFEJC_00414 2.1e-105
KHDCFEJC_00415 1.6e-73
KHDCFEJC_00417 6.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
KHDCFEJC_00418 6.1e-241 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_00419 2.3e-75 T Universal stress protein family
KHDCFEJC_00421 6.5e-34 hol S Bacteriophage holin
KHDCFEJC_00422 4.8e-36 S Haemolysin XhlA
KHDCFEJC_00423 1.9e-161 M Glycosyl hydrolases family 25
KHDCFEJC_00424 1e-54
KHDCFEJC_00427 4e-183
KHDCFEJC_00428 0.0 S Phage minor structural protein
KHDCFEJC_00429 5.7e-231 S Phage tail protein
KHDCFEJC_00430 0.0 S peptidoglycan catabolic process
KHDCFEJC_00433 2.3e-68 S Phage tail tube protein
KHDCFEJC_00434 3.8e-26
KHDCFEJC_00435 1.7e-38
KHDCFEJC_00436 1.1e-25 S Phage head-tail joining protein
KHDCFEJC_00437 1.4e-51 S Phage gp6-like head-tail connector protein
KHDCFEJC_00438 1.2e-206 S peptidase activity
KHDCFEJC_00439 1.6e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KHDCFEJC_00440 5.8e-222 S Phage portal protein
KHDCFEJC_00441 2.8e-25 S Protein of unknown function (DUF1056)
KHDCFEJC_00442 0.0 S Phage Terminase
KHDCFEJC_00443 1.6e-79 L Phage terminase, small subunit
KHDCFEJC_00445 5e-90 L HNH nucleases
KHDCFEJC_00446 3.1e-12 V HNH nucleases
KHDCFEJC_00448 1.1e-74 S Transcriptional regulator, RinA family
KHDCFEJC_00450 1.7e-28
KHDCFEJC_00451 2.5e-10 S YopX protein
KHDCFEJC_00453 8.7e-15
KHDCFEJC_00454 3.9e-38
KHDCFEJC_00455 2.7e-26 S YopX protein
KHDCFEJC_00457 1.8e-14
KHDCFEJC_00459 4e-47
KHDCFEJC_00461 1.3e-145 pi346 L IstB-like ATP binding protein
KHDCFEJC_00462 1.6e-71 L DnaD domain protein
KHDCFEJC_00464 3.6e-38 S Putative HNHc nuclease
KHDCFEJC_00465 3.3e-24 S Putative HNHc nuclease
KHDCFEJC_00471 7.4e-68 S DNA binding
KHDCFEJC_00473 8.4e-94 kilA K BRO family, N-terminal domain
KHDCFEJC_00475 1.2e-28 ps115 K Helix-turn-helix XRE-family like proteins
KHDCFEJC_00476 1.8e-29 E Zn peptidase
KHDCFEJC_00477 7.9e-11 tcdC
KHDCFEJC_00482 7.5e-81 int L Belongs to the 'phage' integrase family
KHDCFEJC_00484 1.5e-247 yfmL 3.6.4.13 L DEAD DEAH box helicase
KHDCFEJC_00485 7.1e-189 mocA S Oxidoreductase
KHDCFEJC_00486 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
KHDCFEJC_00487 3.2e-62 S Domain of unknown function (DUF4828)
KHDCFEJC_00488 4.4e-185 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KHDCFEJC_00489 7e-104 K Bacterial regulatory proteins, tetR family
KHDCFEJC_00490 9.3e-147 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
KHDCFEJC_00491 4.5e-123 yliE T EAL domain
KHDCFEJC_00492 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHDCFEJC_00493 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHDCFEJC_00494 1.6e-129 ybbR S YbbR-like protein
KHDCFEJC_00495 1.7e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHDCFEJC_00496 7.1e-121 S Protein of unknown function (DUF1361)
KHDCFEJC_00497 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
KHDCFEJC_00498 0.0 yjcE P Sodium proton antiporter
KHDCFEJC_00499 1.4e-167 murB 1.3.1.98 M Cell wall formation
KHDCFEJC_00500 7.3e-161 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KHDCFEJC_00501 1.6e-153 xth 3.1.11.2 L exodeoxyribonuclease III
KHDCFEJC_00502 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
KHDCFEJC_00503 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
KHDCFEJC_00504 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KHDCFEJC_00505 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KHDCFEJC_00506 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHDCFEJC_00507 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
KHDCFEJC_00508 6.1e-105 yxjI
KHDCFEJC_00509 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHDCFEJC_00510 1.5e-256 glnP P ABC transporter
KHDCFEJC_00511 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
KHDCFEJC_00512 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
KHDCFEJC_00513 4.2e-16 3.4.21.72 M Bacterial Ig-like domain (group 3)
KHDCFEJC_00514 6e-82 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHDCFEJC_00515 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KHDCFEJC_00516 3.2e-138 est 3.1.1.1 S Serine aminopeptidase, S33
KHDCFEJC_00517 1.2e-30 secG U Preprotein translocase
KHDCFEJC_00518 6.6e-295 clcA P chloride
KHDCFEJC_00519 3.1e-132
KHDCFEJC_00520 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHDCFEJC_00521 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHDCFEJC_00522 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KHDCFEJC_00523 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHDCFEJC_00524 1.8e-187 cggR K Putative sugar-binding domain
KHDCFEJC_00525 1.2e-244 rpoN K Sigma-54 factor, core binding domain
KHDCFEJC_00527 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHDCFEJC_00528 1.1e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHDCFEJC_00529 2.6e-305 oppA E ABC transporter, substratebinding protein
KHDCFEJC_00530 3.7e-168 whiA K May be required for sporulation
KHDCFEJC_00531 1.2e-188 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KHDCFEJC_00532 9.4e-161 rapZ S Displays ATPase and GTPase activities
KHDCFEJC_00533 9.3e-87 S Short repeat of unknown function (DUF308)
KHDCFEJC_00534 3.9e-262 argH 4.3.2.1 E argininosuccinate lyase
KHDCFEJC_00535 2.4e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KHDCFEJC_00536 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHDCFEJC_00537 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHDCFEJC_00538 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHDCFEJC_00539 3.6e-117 yfbR S HD containing hydrolase-like enzyme
KHDCFEJC_00540 9.2e-212 norA EGP Major facilitator Superfamily
KHDCFEJC_00541 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KHDCFEJC_00542 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KHDCFEJC_00543 3.3e-132 yliE T Putative diguanylate phosphodiesterase
KHDCFEJC_00544 6.2e-96 V VanZ like family
KHDCFEJC_00545 1.9e-194 blaA6 V Beta-lactamase
KHDCFEJC_00546 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KHDCFEJC_00547 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHDCFEJC_00548 5.1e-53 yitW S Pfam:DUF59
KHDCFEJC_00549 1.7e-173 S Aldo keto reductase
KHDCFEJC_00550 3.3e-97 FG HIT domain
KHDCFEJC_00551 1.4e-37 S Bacteriocin-protection, YdeI or OmpD-Associated
KHDCFEJC_00552 5.3e-77
KHDCFEJC_00553 2e-120 E GDSL-like Lipase/Acylhydrolase family
KHDCFEJC_00554 1.5e-305 U Belongs to the BCCT transporter (TC 2.A.15) family
KHDCFEJC_00555 0.0 cadA P P-type ATPase
KHDCFEJC_00557 4.8e-125 yyaQ S YjbR
KHDCFEJC_00558 3.5e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
KHDCFEJC_00559 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHDCFEJC_00560 1.3e-196 frlB M SIS domain
KHDCFEJC_00561 8e-27 3.2.2.10 S Belongs to the LOG family
KHDCFEJC_00562 1.2e-255 nhaC C Na H antiporter NhaC
KHDCFEJC_00563 8.9e-251 cycA E Amino acid permease
KHDCFEJC_00564 1.8e-167 S Alpha/beta hydrolase of unknown function (DUF915)
KHDCFEJC_00565 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
KHDCFEJC_00566 4.8e-162 azoB GM NmrA-like family
KHDCFEJC_00567 4.1e-66 K Winged helix DNA-binding domain
KHDCFEJC_00568 7e-71 spx4 1.20.4.1 P ArsC family
KHDCFEJC_00569 1.7e-66 yeaO S Protein of unknown function, DUF488
KHDCFEJC_00570 4e-53
KHDCFEJC_00571 4.1e-214 mutY L A G-specific adenine glycosylase
KHDCFEJC_00572 1.9e-62
KHDCFEJC_00573 4.3e-86
KHDCFEJC_00574 1.2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
KHDCFEJC_00575 7e-56
KHDCFEJC_00576 2.1e-14
KHDCFEJC_00577 1.1e-115 GM NmrA-like family
KHDCFEJC_00578 1.3e-81 elaA S GNAT family
KHDCFEJC_00579 1.6e-158 EG EamA-like transporter family
KHDCFEJC_00580 1.8e-119 S membrane
KHDCFEJC_00581 6.8e-111 S VIT family
KHDCFEJC_00582 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KHDCFEJC_00583 0.0 copB 3.6.3.4 P P-type ATPase
KHDCFEJC_00584 9.4e-74 copR K Copper transport repressor CopY TcrY
KHDCFEJC_00585 2.1e-39
KHDCFEJC_00586 3.5e-73 S COG NOG18757 non supervised orthologous group
KHDCFEJC_00587 4.3e-248 lmrB EGP Major facilitator Superfamily
KHDCFEJC_00588 5e-24
KHDCFEJC_00589 4.2e-49
KHDCFEJC_00590 1.6e-64 ycgX S Protein of unknown function (DUF1398)
KHDCFEJC_00591 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
KHDCFEJC_00592 5.9e-214 mdtG EGP Major facilitator Superfamily
KHDCFEJC_00593 1.2e-179 D Alpha beta
KHDCFEJC_00594 3.4e-77 M1-874 K Domain of unknown function (DUF1836)
KHDCFEJC_00595 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
KHDCFEJC_00596 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
KHDCFEJC_00597 2.1e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KHDCFEJC_00598 8.4e-152 ywkB S Membrane transport protein
KHDCFEJC_00599 5.2e-164 yvgN C Aldo keto reductase
KHDCFEJC_00600 9.2e-133 thrE S Putative threonine/serine exporter
KHDCFEJC_00601 7.5e-77 S Threonine/Serine exporter, ThrE
KHDCFEJC_00602 2.3e-43 S Protein of unknown function (DUF1093)
KHDCFEJC_00603 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KHDCFEJC_00604 1.7e-90 ymdB S Macro domain protein
KHDCFEJC_00605 5.8e-95 K transcriptional regulator
KHDCFEJC_00606 5.5e-50 yvlA
KHDCFEJC_00607 3e-160 ypuA S Protein of unknown function (DUF1002)
KHDCFEJC_00608 0.0
KHDCFEJC_00609 2.9e-185 S Bacterial protein of unknown function (DUF916)
KHDCFEJC_00610 1.7e-129 S WxL domain surface cell wall-binding
KHDCFEJC_00611 1.5e-135 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
KHDCFEJC_00612 1.7e-43 ankB S ankyrin repeats
KHDCFEJC_00613 2.1e-31
KHDCFEJC_00614 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KHDCFEJC_00615 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHDCFEJC_00616 4.1e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
KHDCFEJC_00617 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHDCFEJC_00618 2.6e-183 S DUF218 domain
KHDCFEJC_00619 2.2e-126
KHDCFEJC_00620 1.7e-148 yxeH S hydrolase
KHDCFEJC_00621 2.5e-261 ywfO S HD domain protein
KHDCFEJC_00622 4.8e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
KHDCFEJC_00623 3.8e-78 ywiB S Domain of unknown function (DUF1934)
KHDCFEJC_00624 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KHDCFEJC_00625 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHDCFEJC_00626 1.8e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHDCFEJC_00627 3.1e-229 tdcC E amino acid
KHDCFEJC_00628 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KHDCFEJC_00629 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KHDCFEJC_00630 2.9e-131 S YheO-like PAS domain
KHDCFEJC_00631 5.1e-27
KHDCFEJC_00632 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHDCFEJC_00633 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHDCFEJC_00634 7.8e-41 rpmE2 J Ribosomal protein L31
KHDCFEJC_00635 1.2e-213 J translation release factor activity
KHDCFEJC_00636 9.2e-127 srtA 3.4.22.70 M sortase family
KHDCFEJC_00637 1.7e-91 lemA S LemA family
KHDCFEJC_00638 2.1e-139 htpX O Belongs to the peptidase M48B family
KHDCFEJC_00639 2e-146
KHDCFEJC_00640 1.1e-259 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHDCFEJC_00641 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KHDCFEJC_00642 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHDCFEJC_00643 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHDCFEJC_00644 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
KHDCFEJC_00645 0.0 kup P Transport of potassium into the cell
KHDCFEJC_00646 8.5e-193 P ABC transporter, substratebinding protein
KHDCFEJC_00647 8.3e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
KHDCFEJC_00648 5e-134 P ATPases associated with a variety of cellular activities
KHDCFEJC_00649 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KHDCFEJC_00650 2.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHDCFEJC_00651 1.2e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHDCFEJC_00652 3.4e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KHDCFEJC_00653 8e-129 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
KHDCFEJC_00654 6.7e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
KHDCFEJC_00655 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHDCFEJC_00656 4.1e-84 S QueT transporter
KHDCFEJC_00657 2.1e-114 S (CBS) domain
KHDCFEJC_00658 1.9e-264 S Putative peptidoglycan binding domain
KHDCFEJC_00659 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KHDCFEJC_00660 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHDCFEJC_00661 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHDCFEJC_00662 1.4e-287 yabM S Polysaccharide biosynthesis protein
KHDCFEJC_00663 2.2e-42 yabO J S4 domain protein
KHDCFEJC_00665 1.1e-63 divIC D Septum formation initiator
KHDCFEJC_00666 3.1e-74 yabR J RNA binding
KHDCFEJC_00667 1.1e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHDCFEJC_00668 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KHDCFEJC_00669 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHDCFEJC_00670 3.8e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHDCFEJC_00671 4.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHDCFEJC_00672 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KHDCFEJC_00673 1.1e-34 EGP Major facilitator Superfamily
KHDCFEJC_00674 4.4e-77 uvrA3 L excinuclease ABC
KHDCFEJC_00675 0.0 uvrA3 L excinuclease ABC
KHDCFEJC_00676 0.0 S Predicted membrane protein (DUF2207)
KHDCFEJC_00677 5.3e-147 3.1.3.102, 3.1.3.104 S hydrolase
KHDCFEJC_00678 3.2e-308 ybiT S ABC transporter, ATP-binding protein
KHDCFEJC_00679 3.8e-221 S CAAX protease self-immunity
KHDCFEJC_00680 4.5e-122 2.7.1.89 M Phosphotransferase enzyme family
KHDCFEJC_00681 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
KHDCFEJC_00682 7.7e-97 speG J Acetyltransferase (GNAT) domain
KHDCFEJC_00683 1.4e-138 endA F DNA RNA non-specific endonuclease
KHDCFEJC_00684 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
KHDCFEJC_00685 1.5e-95 K Transcriptional regulator (TetR family)
KHDCFEJC_00686 3.8e-187 yhgE V domain protein
KHDCFEJC_00687 8e-09
KHDCFEJC_00690 6.7e-246 EGP Major facilitator Superfamily
KHDCFEJC_00691 0.0 mdlA V ABC transporter
KHDCFEJC_00692 0.0 mdlB V ABC transporter
KHDCFEJC_00694 1.2e-194 C Aldo/keto reductase family
KHDCFEJC_00695 7.4e-102 M Protein of unknown function (DUF3737)
KHDCFEJC_00696 1.3e-221 patB 4.4.1.8 E Aminotransferase, class I
KHDCFEJC_00697 9.2e-104 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
KHDCFEJC_00698 2.1e-31
KHDCFEJC_00699 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KHDCFEJC_00700 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
KHDCFEJC_00701 6.1e-76 T Belongs to the universal stress protein A family
KHDCFEJC_00702 1.3e-34
KHDCFEJC_00703 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
KHDCFEJC_00704 5.8e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KHDCFEJC_00705 1.9e-104 GM NAD(P)H-binding
KHDCFEJC_00706 6.9e-156 K LysR substrate binding domain
KHDCFEJC_00707 3.8e-63 S Domain of unknown function (DUF4440)
KHDCFEJC_00708 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
KHDCFEJC_00709 8.2e-48
KHDCFEJC_00710 1.3e-35
KHDCFEJC_00711 2.8e-85 yvbK 3.1.3.25 K GNAT family
KHDCFEJC_00712 3.8e-84
KHDCFEJC_00714 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KHDCFEJC_00715 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KHDCFEJC_00716 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHDCFEJC_00718 3.7e-120 macB V ABC transporter, ATP-binding protein
KHDCFEJC_00719 0.0 ylbB V ABC transporter permease
KHDCFEJC_00720 2e-236 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KHDCFEJC_00721 9.8e-79 K transcriptional regulator, MerR family
KHDCFEJC_00722 3.2e-76 yphH S Cupin domain
KHDCFEJC_00723 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
KHDCFEJC_00724 1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHDCFEJC_00725 4.7e-211 natB CP ABC-2 family transporter protein
KHDCFEJC_00726 1.4e-167 natA S ABC transporter, ATP-binding protein
KHDCFEJC_00727 2e-91 ogt 2.1.1.63 L Methyltransferase
KHDCFEJC_00728 4.3e-51 lytE M LysM domain
KHDCFEJC_00730 7.6e-267 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
KHDCFEJC_00731 9e-297 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
KHDCFEJC_00732 3.7e-151 rlrG K Transcriptional regulator
KHDCFEJC_00733 9.3e-173 S Conserved hypothetical protein 698
KHDCFEJC_00734 6.9e-101 rimL J Acetyltransferase (GNAT) domain
KHDCFEJC_00735 4e-76 S Domain of unknown function (DUF4811)
KHDCFEJC_00736 3.2e-270 lmrB EGP Major facilitator Superfamily
KHDCFEJC_00737 2.9e-122 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KHDCFEJC_00738 7.6e-190 ynfM EGP Major facilitator Superfamily
KHDCFEJC_00739 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
KHDCFEJC_00740 1.2e-155 mleP3 S Membrane transport protein
KHDCFEJC_00741 7.5e-118 S Membrane
KHDCFEJC_00742 1.7e-186 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KHDCFEJC_00743 8.1e-99 1.5.1.3 H RibD C-terminal domain
KHDCFEJC_00744 1.5e-183 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KHDCFEJC_00745 1.4e-90 2.7.7.65 T phosphorelay sensor kinase activity
KHDCFEJC_00746 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KHDCFEJC_00747 1.2e-173 hrtB V ABC transporter permease
KHDCFEJC_00748 6.6e-95 S Protein of unknown function (DUF1440)
KHDCFEJC_00749 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHDCFEJC_00750 1.9e-147 KT helix_turn_helix, mercury resistance
KHDCFEJC_00751 1.6e-115 S Protein of unknown function (DUF554)
KHDCFEJC_00752 1.4e-92 yueI S Protein of unknown function (DUF1694)
KHDCFEJC_00753 2e-143 yvpB S Peptidase_C39 like family
KHDCFEJC_00754 2.8e-153 M Glycosyl hydrolases family 25
KHDCFEJC_00755 3.9e-111
KHDCFEJC_00756 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHDCFEJC_00757 1.8e-84 hmpT S Pfam:DUF3816
KHDCFEJC_00758 4.7e-80 S response to antibiotic
KHDCFEJC_00759 4.3e-169 S response to antibiotic
KHDCFEJC_00760 8.8e-136 S zinc-ribbon domain
KHDCFEJC_00762 3.2e-37
KHDCFEJC_00763 2.7e-137 aroD S Alpha/beta hydrolase family
KHDCFEJC_00764 5.2e-177 S Phosphotransferase system, EIIC
KHDCFEJC_00765 5.1e-270 I acetylesterase activity
KHDCFEJC_00766 1.2e-223 sdrF M Collagen binding domain
KHDCFEJC_00767 1.1e-159 yicL EG EamA-like transporter family
KHDCFEJC_00768 4.4e-129 E lipolytic protein G-D-S-L family
KHDCFEJC_00769 1.7e-176 4.1.1.52 S Amidohydrolase
KHDCFEJC_00770 5.1e-113 K Transcriptional regulator C-terminal region
KHDCFEJC_00771 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
KHDCFEJC_00772 1.2e-160 ypbG 2.7.1.2 GK ROK family
KHDCFEJC_00773 0.0 ybfG M peptidoglycan-binding domain-containing protein
KHDCFEJC_00774 3.6e-88
KHDCFEJC_00775 0.0 lmrA 3.6.3.44 V ABC transporter
KHDCFEJC_00776 5e-93 rmaB K Transcriptional regulator, MarR family
KHDCFEJC_00777 7.1e-159 ccpB 5.1.1.1 K lacI family
KHDCFEJC_00778 8.7e-121 yceE S haloacid dehalogenase-like hydrolase
KHDCFEJC_00779 2.9e-119 drgA C Nitroreductase family
KHDCFEJC_00780 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
KHDCFEJC_00781 7.1e-116 cmpC S ATPases associated with a variety of cellular activities
KHDCFEJC_00782 8.7e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
KHDCFEJC_00783 2.3e-168 XK27_00670 S ABC transporter
KHDCFEJC_00784 1e-260
KHDCFEJC_00785 7.3e-62
KHDCFEJC_00786 1.1e-189 S Cell surface protein
KHDCFEJC_00787 2.3e-91 S WxL domain surface cell wall-binding
KHDCFEJC_00788 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
KHDCFEJC_00789 1e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
KHDCFEJC_00790 3.3e-124 livF E ABC transporter
KHDCFEJC_00791 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
KHDCFEJC_00792 5.3e-141 livM E Branched-chain amino acid transport system / permease component
KHDCFEJC_00793 6.5e-154 livH U Branched-chain amino acid transport system / permease component
KHDCFEJC_00794 1.2e-211 livJ E Receptor family ligand binding region
KHDCFEJC_00796 7e-33
KHDCFEJC_00797 1.7e-113 zmp3 O Zinc-dependent metalloprotease
KHDCFEJC_00798 2.8e-82 gtrA S GtrA-like protein
KHDCFEJC_00799 8.5e-122 K Helix-turn-helix XRE-family like proteins
KHDCFEJC_00800 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
KHDCFEJC_00801 6.8e-72 T Belongs to the universal stress protein A family
KHDCFEJC_00802 6.9e-46
KHDCFEJC_00803 7.1e-116 S SNARE associated Golgi protein
KHDCFEJC_00804 2e-49 K Transcriptional regulator, ArsR family
KHDCFEJC_00805 1.2e-95 cadD P Cadmium resistance transporter
KHDCFEJC_00806 0.0 yhcA V ABC transporter, ATP-binding protein
KHDCFEJC_00807 0.0 P Concanavalin A-like lectin/glucanases superfamily
KHDCFEJC_00808 6.1e-113 P Concanavalin A-like lectin/glucanases superfamily
KHDCFEJC_00809 7.4e-64
KHDCFEJC_00810 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
KHDCFEJC_00811 7.2e-55
KHDCFEJC_00812 5.3e-150 dicA K Helix-turn-helix domain
KHDCFEJC_00813 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHDCFEJC_00814 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KHDCFEJC_00815 2.7e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_00816 2.9e-278 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_00817 9.7e-186 1.1.1.219 GM Male sterility protein
KHDCFEJC_00818 2.7e-76 K helix_turn_helix, mercury resistance
KHDCFEJC_00819 7.3e-63 M LysM domain
KHDCFEJC_00820 2.3e-95 M Lysin motif
KHDCFEJC_00821 4.7e-108 S SdpI/YhfL protein family
KHDCFEJC_00822 1.8e-54 nudA S ASCH
KHDCFEJC_00823 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
KHDCFEJC_00824 5.5e-92
KHDCFEJC_00825 1.5e-120 tag 3.2.2.20 L Methyladenine glycosylase
KHDCFEJC_00826 3.3e-219 T diguanylate cyclase
KHDCFEJC_00827 1.2e-73 S Psort location Cytoplasmic, score
KHDCFEJC_00828 1.8e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
KHDCFEJC_00829 8.6e-218 ykiI
KHDCFEJC_00830 6.5e-301 V ABC transporter
KHDCFEJC_00831 1.8e-18 V ABC transporter
KHDCFEJC_00832 2.1e-299 XK27_09600 V ABC transporter, ATP-binding protein
KHDCFEJC_00833 3.5e-42
KHDCFEJC_00834 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
KHDCFEJC_00835 7.7e-163 IQ KR domain
KHDCFEJC_00837 7.4e-71
KHDCFEJC_00838 1.3e-143 K Helix-turn-helix XRE-family like proteins
KHDCFEJC_00839 2.8e-266 yjeM E Amino Acid
KHDCFEJC_00840 1.1e-65 lysM M LysM domain
KHDCFEJC_00841 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
KHDCFEJC_00842 4.6e-213 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
KHDCFEJC_00843 0.0 ctpA 3.6.3.54 P P-type ATPase
KHDCFEJC_00844 2.7e-42 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KHDCFEJC_00845 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KHDCFEJC_00846 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KHDCFEJC_00847 7.6e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KHDCFEJC_00848 2.7e-183 ywhK S Membrane
KHDCFEJC_00849 3.4e-163 degV S Uncharacterised protein, DegV family COG1307
KHDCFEJC_00850 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KHDCFEJC_00851 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHDCFEJC_00852 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHDCFEJC_00853 5e-145 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHDCFEJC_00854 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHDCFEJC_00855 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHDCFEJC_00856 1.2e-224 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHDCFEJC_00857 3.5e-142 cad S FMN_bind
KHDCFEJC_00858 0.0 ndh 1.6.99.3 C NADH dehydrogenase
KHDCFEJC_00859 1.4e-86 ynhH S NusG domain II
KHDCFEJC_00860 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
KHDCFEJC_00861 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KHDCFEJC_00862 2.1e-61 rplQ J Ribosomal protein L17
KHDCFEJC_00863 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHDCFEJC_00864 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHDCFEJC_00865 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHDCFEJC_00866 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHDCFEJC_00867 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHDCFEJC_00868 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHDCFEJC_00869 6.3e-70 rplO J Binds to the 23S rRNA
KHDCFEJC_00870 2.2e-24 rpmD J Ribosomal protein L30
KHDCFEJC_00871 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHDCFEJC_00872 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHDCFEJC_00873 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHDCFEJC_00874 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHDCFEJC_00875 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHDCFEJC_00876 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHDCFEJC_00877 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHDCFEJC_00878 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHDCFEJC_00879 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
KHDCFEJC_00880 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHDCFEJC_00881 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHDCFEJC_00882 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHDCFEJC_00883 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHDCFEJC_00884 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHDCFEJC_00885 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHDCFEJC_00886 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
KHDCFEJC_00887 7.5e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHDCFEJC_00888 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KHDCFEJC_00889 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHDCFEJC_00890 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHDCFEJC_00891 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHDCFEJC_00892 7.8e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KHDCFEJC_00893 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHDCFEJC_00894 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHDCFEJC_00895 1.5e-109 K Bacterial regulatory proteins, tetR family
KHDCFEJC_00896 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHDCFEJC_00897 6.9e-78 ctsR K Belongs to the CtsR family
KHDCFEJC_00905 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHDCFEJC_00906 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KHDCFEJC_00907 5.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KHDCFEJC_00908 1.5e-264 lysP E amino acid
KHDCFEJC_00909 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KHDCFEJC_00910 4.2e-92 K Transcriptional regulator
KHDCFEJC_00911 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
KHDCFEJC_00912 2e-154 I alpha/beta hydrolase fold
KHDCFEJC_00913 3.9e-119 lssY 3.6.1.27 I phosphatase
KHDCFEJC_00914 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHDCFEJC_00915 2.2e-76 S Threonine/Serine exporter, ThrE
KHDCFEJC_00916 3.3e-130 thrE S Putative threonine/serine exporter
KHDCFEJC_00917 6e-31 cspC K Cold shock protein
KHDCFEJC_00918 2e-120 sirR K iron dependent repressor
KHDCFEJC_00919 1.3e-57
KHDCFEJC_00920 1.7e-84 merR K MerR HTH family regulatory protein
KHDCFEJC_00921 7e-270 lmrB EGP Major facilitator Superfamily
KHDCFEJC_00922 1.4e-117 S Domain of unknown function (DUF4811)
KHDCFEJC_00923 9.3e-106
KHDCFEJC_00924 4.4e-35 yyaN K MerR HTH family regulatory protein
KHDCFEJC_00925 1.7e-120 azlC E branched-chain amino acid
KHDCFEJC_00926 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
KHDCFEJC_00927 0.0 asnB 6.3.5.4 E Asparagine synthase
KHDCFEJC_00928 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KHDCFEJC_00929 5.8e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHDCFEJC_00930 1e-254 xylP2 G symporter
KHDCFEJC_00931 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
KHDCFEJC_00932 5.6e-49
KHDCFEJC_00933 4.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KHDCFEJC_00934 5.7e-103 3.2.2.20 K FR47-like protein
KHDCFEJC_00935 1.3e-126 yibF S overlaps another CDS with the same product name
KHDCFEJC_00936 1.4e-218 yibE S overlaps another CDS with the same product name
KHDCFEJC_00937 2.5e-178
KHDCFEJC_00938 5.6e-138 S NADPH-dependent FMN reductase
KHDCFEJC_00939 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
KHDCFEJC_00940 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KHDCFEJC_00941 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KHDCFEJC_00942 4.1e-32 L leucine-zipper of insertion element IS481
KHDCFEJC_00943 8.5e-41
KHDCFEJC_00944 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KHDCFEJC_00945 3.3e-277 pipD E Dipeptidase
KHDCFEJC_00946 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
KHDCFEJC_00947 3.1e-50
KHDCFEJC_00948 1.6e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KHDCFEJC_00949 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
KHDCFEJC_00950 2.9e-179 citR K sugar-binding domain protein
KHDCFEJC_00951 1.7e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
KHDCFEJC_00952 5.7e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KHDCFEJC_00953 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
KHDCFEJC_00954 6.7e-162 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
KHDCFEJC_00955 2.3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
KHDCFEJC_00956 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KHDCFEJC_00957 2.8e-252 frdC 1.3.5.4 C FAD binding domain
KHDCFEJC_00958 1.4e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KHDCFEJC_00959 4.9e-162 mleR K LysR family transcriptional regulator
KHDCFEJC_00960 1.8e-167 mleR K LysR family
KHDCFEJC_00961 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KHDCFEJC_00962 1.4e-165 mleP S Sodium Bile acid symporter family
KHDCFEJC_00963 5.8e-253 yfnA E Amino Acid
KHDCFEJC_00964 2e-98 S ECF transporter, substrate-specific component
KHDCFEJC_00965 1.8e-23
KHDCFEJC_00966 1.6e-283 S Alpha beta
KHDCFEJC_00967 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
KHDCFEJC_00968 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KHDCFEJC_00969 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KHDCFEJC_00970 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHDCFEJC_00971 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
KHDCFEJC_00972 2.8e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KHDCFEJC_00973 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KHDCFEJC_00974 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
KHDCFEJC_00975 9e-113 acmA 3.2.1.17 NU mannosyl-glycoprotein
KHDCFEJC_00976 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHDCFEJC_00977 4.9e-85 S UPF0316 protein
KHDCFEJC_00978 1.1e-217 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHDCFEJC_00979 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KHDCFEJC_00980 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHDCFEJC_00981 2.6e-198 camS S sex pheromone
KHDCFEJC_00982 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHDCFEJC_00983 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHDCFEJC_00984 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHDCFEJC_00985 1e-190 yegS 2.7.1.107 G Lipid kinase
KHDCFEJC_00986 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHDCFEJC_00987 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
KHDCFEJC_00988 0.0 yfgQ P E1-E2 ATPase
KHDCFEJC_00989 1.4e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_00990 4.3e-166 S Alpha/beta hydrolase of unknown function (DUF915)
KHDCFEJC_00991 2.3e-151 gntR K rpiR family
KHDCFEJC_00992 4.1e-144 lys M Glycosyl hydrolases family 25
KHDCFEJC_00993 1.6e-126 L Transposase
KHDCFEJC_00994 6.5e-162 L Transposase
KHDCFEJC_00995 2.3e-231 S Sterol carrier protein domain
KHDCFEJC_00996 1.4e-211 S Bacterial protein of unknown function (DUF871)
KHDCFEJC_00997 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
KHDCFEJC_00998 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
KHDCFEJC_00999 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
KHDCFEJC_01000 1.7e-102 3.6.1.13 L Belongs to the Nudix hydrolase family
KHDCFEJC_01001 2.8e-96 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KHDCFEJC_01002 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
KHDCFEJC_01003 2.9e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
KHDCFEJC_01004 3.6e-282 thrC 4.2.3.1 E Threonine synthase
KHDCFEJC_01005 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KHDCFEJC_01007 1.5e-52
KHDCFEJC_01008 5.4e-118
KHDCFEJC_01009 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
KHDCFEJC_01010 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
KHDCFEJC_01012 5e-51
KHDCFEJC_01013 1.1e-88
KHDCFEJC_01014 5.5e-71 gtcA S Teichoic acid glycosylation protein
KHDCFEJC_01015 4e-34
KHDCFEJC_01016 6.7e-81 uspA T universal stress protein
KHDCFEJC_01017 5.1e-137
KHDCFEJC_01018 6.9e-164 V ABC transporter, ATP-binding protein
KHDCFEJC_01019 3.9e-60 gntR1 K Transcriptional regulator, GntR family
KHDCFEJC_01020 3e-41
KHDCFEJC_01021 0.0 V FtsX-like permease family
KHDCFEJC_01022 1.7e-139 cysA V ABC transporter, ATP-binding protein
KHDCFEJC_01023 5.8e-180 ansA 3.5.1.1 EJ Asparaginase
KHDCFEJC_01024 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
KHDCFEJC_01025 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
KHDCFEJC_01026 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
KHDCFEJC_01027 4.9e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
KHDCFEJC_01028 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
KHDCFEJC_01029 1.5e-223 XK27_09615 1.3.5.4 S reductase
KHDCFEJC_01030 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHDCFEJC_01031 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHDCFEJC_01032 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KHDCFEJC_01033 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHDCFEJC_01034 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHDCFEJC_01035 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHDCFEJC_01036 4.8e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHDCFEJC_01037 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KHDCFEJC_01038 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHDCFEJC_01039 8.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KHDCFEJC_01040 5.4e-215 purD 6.3.4.13 F Belongs to the GARS family
KHDCFEJC_01041 2e-123 2.1.1.14 E Methionine synthase
KHDCFEJC_01042 1.7e-51 pgaC GT2 M Glycosyl transferase
KHDCFEJC_01043 1.9e-67 tspO T TspO/MBR family
KHDCFEJC_01044 6.3e-76 uspA T Belongs to the universal stress protein A family
KHDCFEJC_01045 8e-66 S Protein of unknown function (DUF805)
KHDCFEJC_01046 3.2e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
KHDCFEJC_01047 1.3e-35
KHDCFEJC_01048 3.1e-14
KHDCFEJC_01049 2.5e-40 S transglycosylase associated protein
KHDCFEJC_01050 4.8e-29 S CsbD-like
KHDCFEJC_01051 9.4e-40
KHDCFEJC_01052 8.6e-281 pipD E Dipeptidase
KHDCFEJC_01053 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KHDCFEJC_01054 1.8e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHDCFEJC_01055 7.3e-167 2.5.1.74 H UbiA prenyltransferase family
KHDCFEJC_01056 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
KHDCFEJC_01057 6.3e-45
KHDCFEJC_01058 1.7e-44
KHDCFEJC_01059 1.1e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHDCFEJC_01060 4.8e-266 yfnA E Amino Acid
KHDCFEJC_01061 1.2e-149 yitU 3.1.3.104 S hydrolase
KHDCFEJC_01062 5.5e-269 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KHDCFEJC_01063 6.1e-88 S Domain of unknown function (DUF4767)
KHDCFEJC_01065 2.5e-250 malT G Major Facilitator
KHDCFEJC_01066 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KHDCFEJC_01067 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KHDCFEJC_01068 6.2e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KHDCFEJC_01069 5e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KHDCFEJC_01070 2.4e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KHDCFEJC_01071 3.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KHDCFEJC_01072 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KHDCFEJC_01073 2.1e-72 ypmB S protein conserved in bacteria
KHDCFEJC_01074 4.3e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KHDCFEJC_01075 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KHDCFEJC_01076 1.3e-128 dnaD L Replication initiation and membrane attachment
KHDCFEJC_01078 3.9e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHDCFEJC_01079 2e-99 metI P ABC transporter permease
KHDCFEJC_01080 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
KHDCFEJC_01081 4.4e-83 uspA T Universal stress protein family
KHDCFEJC_01082 1.4e-301 ftpA P Binding-protein-dependent transport system inner membrane component
KHDCFEJC_01083 1.7e-182 ftpB P Bacterial extracellular solute-binding protein
KHDCFEJC_01084 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
KHDCFEJC_01085 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KHDCFEJC_01086 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KHDCFEJC_01087 2.4e-109 ypsA S Belongs to the UPF0398 family
KHDCFEJC_01088 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KHDCFEJC_01090 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KHDCFEJC_01091 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
KHDCFEJC_01092 1.8e-243 P Major Facilitator Superfamily
KHDCFEJC_01093 4e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KHDCFEJC_01094 1.7e-72 S SnoaL-like domain
KHDCFEJC_01095 2.8e-241 M Glycosyltransferase, group 2 family protein
KHDCFEJC_01096 4.3e-208 mccF V LD-carboxypeptidase
KHDCFEJC_01097 1.4e-78 K Acetyltransferase (GNAT) domain
KHDCFEJC_01098 2.6e-239 M hydrolase, family 25
KHDCFEJC_01099 2.3e-181 mccF 3.4.17.13 V LD-carboxypeptidase
KHDCFEJC_01100 1.3e-123
KHDCFEJC_01101 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
KHDCFEJC_01102 2.3e-193
KHDCFEJC_01103 1.5e-146 S hydrolase activity, acting on ester bonds
KHDCFEJC_01104 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
KHDCFEJC_01105 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
KHDCFEJC_01106 2.2e-61 esbA S Family of unknown function (DUF5322)
KHDCFEJC_01107 2.3e-293 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KHDCFEJC_01108 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHDCFEJC_01109 3.5e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHDCFEJC_01110 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHDCFEJC_01111 2.8e-207 carA 6.3.5.5 F Belongs to the CarA family
KHDCFEJC_01112 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KHDCFEJC_01113 6.4e-113 pgm5 G Phosphoglycerate mutase family
KHDCFEJC_01114 2.8e-38 frataxin S Domain of unknown function (DU1801)
KHDCFEJC_01118 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
KHDCFEJC_01119 3.5e-69 S LuxR family transcriptional regulator
KHDCFEJC_01120 8.6e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
KHDCFEJC_01122 4.8e-90 3.6.1.55 F NUDIX domain
KHDCFEJC_01123 1.6e-163 V ABC transporter, ATP-binding protein
KHDCFEJC_01124 1.3e-131 S ABC-2 family transporter protein
KHDCFEJC_01125 0.0 FbpA K Fibronectin-binding protein
KHDCFEJC_01126 1.9e-66 K Transcriptional regulator
KHDCFEJC_01127 7e-161 degV S EDD domain protein, DegV family
KHDCFEJC_01128 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
KHDCFEJC_01129 7.6e-132 S Protein of unknown function (DUF975)
KHDCFEJC_01130 1.7e-09
KHDCFEJC_01131 2.4e-49
KHDCFEJC_01132 4.8e-148 2.7.7.12 C Domain of unknown function (DUF4931)
KHDCFEJC_01133 1.6e-211 pmrB EGP Major facilitator Superfamily
KHDCFEJC_01134 4.6e-12
KHDCFEJC_01135 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
KHDCFEJC_01136 4.6e-129 yejC S Protein of unknown function (DUF1003)
KHDCFEJC_01137 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
KHDCFEJC_01138 1.1e-245 cycA E Amino acid permease
KHDCFEJC_01139 1.6e-120
KHDCFEJC_01140 4.1e-59
KHDCFEJC_01141 1.1e-279 lldP C L-lactate permease
KHDCFEJC_01142 1.4e-227
KHDCFEJC_01143 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KHDCFEJC_01144 2.8e-193 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KHDCFEJC_01145 6.8e-217 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHDCFEJC_01146 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHDCFEJC_01147 1.2e-94 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KHDCFEJC_01148 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
KHDCFEJC_01149 6e-252 gshR1 1.8.1.7 C Glutathione reductase
KHDCFEJC_01150 1.8e-66
KHDCFEJC_01151 6.3e-246 M Glycosyl transferase family group 2
KHDCFEJC_01152 5.7e-275 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHDCFEJC_01153 5.2e-173 htrA 3.4.21.107 O serine protease
KHDCFEJC_01154 8.9e-158 vicX 3.1.26.11 S domain protein
KHDCFEJC_01155 2.2e-151 yycI S YycH protein
KHDCFEJC_01156 1.2e-244 yycH S YycH protein
KHDCFEJC_01157 0.0 vicK 2.7.13.3 T Histidine kinase
KHDCFEJC_01158 6.2e-131 K response regulator
KHDCFEJC_01160 1.7e-37
KHDCFEJC_01161 1.6e-31 cspA K Cold shock protein domain
KHDCFEJC_01162 8.3e-20 S Pyridoxamine 5'-phosphate oxidase
KHDCFEJC_01163 2e-32 S Pyridoxamine 5'-phosphate oxidase
KHDCFEJC_01164 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
KHDCFEJC_01165 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KHDCFEJC_01166 4.5e-143 S haloacid dehalogenase-like hydrolase
KHDCFEJC_01168 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
KHDCFEJC_01169 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KHDCFEJC_01170 6.8e-278 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
KHDCFEJC_01171 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
KHDCFEJC_01172 7.2e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHDCFEJC_01173 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHDCFEJC_01174 6.1e-275 E ABC transporter, substratebinding protein
KHDCFEJC_01176 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHDCFEJC_01177 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHDCFEJC_01178 8.8e-226 yttB EGP Major facilitator Superfamily
KHDCFEJC_01179 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KHDCFEJC_01180 1.4e-67 rplI J Binds to the 23S rRNA
KHDCFEJC_01181 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KHDCFEJC_01182 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHDCFEJC_01183 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KHDCFEJC_01184 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
KHDCFEJC_01185 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHDCFEJC_01186 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHDCFEJC_01187 7.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHDCFEJC_01188 5e-37 yaaA S S4 domain protein YaaA
KHDCFEJC_01189 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHDCFEJC_01190 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHDCFEJC_01191 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KHDCFEJC_01192 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHDCFEJC_01193 1e-309 E ABC transporter, substratebinding protein
KHDCFEJC_01194 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
KHDCFEJC_01195 9.1e-109 jag S R3H domain protein
KHDCFEJC_01196 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHDCFEJC_01197 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KHDCFEJC_01198 6.9e-93 S Cell surface protein
KHDCFEJC_01199 8e-159 S Bacterial protein of unknown function (DUF916)
KHDCFEJC_01201 1.2e-301
KHDCFEJC_01202 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KHDCFEJC_01204 1.5e-255 pepC 3.4.22.40 E aminopeptidase
KHDCFEJC_01205 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
KHDCFEJC_01206 2.8e-157 degV S DegV family
KHDCFEJC_01207 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
KHDCFEJC_01208 6.7e-142 tesE Q hydratase
KHDCFEJC_01209 1.6e-102 padC Q Phenolic acid decarboxylase
KHDCFEJC_01210 2.2e-99 padR K Virulence activator alpha C-term
KHDCFEJC_01211 2.7e-79 T Universal stress protein family
KHDCFEJC_01212 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KHDCFEJC_01213 6.2e-54
KHDCFEJC_01214 1.7e-08
KHDCFEJC_01216 5.2e-188 rbsR K helix_turn _helix lactose operon repressor
KHDCFEJC_01217 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHDCFEJC_01218 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KHDCFEJC_01219 2.7e-160 rbsU U ribose uptake protein RbsU
KHDCFEJC_01220 3.8e-145 IQ NAD dependent epimerase/dehydratase family
KHDCFEJC_01221 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
KHDCFEJC_01222 4.3e-86 gutM K Glucitol operon activator protein (GutM)
KHDCFEJC_01223 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
KHDCFEJC_01224 1.1e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
KHDCFEJC_01225 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KHDCFEJC_01226 1.2e-45 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KHDCFEJC_01227 1.5e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KHDCFEJC_01228 2.1e-171 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
KHDCFEJC_01229 7.8e-82 S Haem-degrading
KHDCFEJC_01230 4.5e-191 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
KHDCFEJC_01231 4.5e-269 iolT EGP Major facilitator Superfamily
KHDCFEJC_01232 4.7e-196 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
KHDCFEJC_01233 2.5e-177 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KHDCFEJC_01234 7.6e-202 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KHDCFEJC_01235 8.6e-198 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
KHDCFEJC_01236 2.4e-259 iolT EGP Major facilitator Superfamily
KHDCFEJC_01237 1.2e-134 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
KHDCFEJC_01239 1.1e-249 pts36C G PTS system sugar-specific permease component
KHDCFEJC_01240 7.3e-52 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
KHDCFEJC_01241 4.2e-80 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHDCFEJC_01242 2.3e-139 K DeoR C terminal sensor domain
KHDCFEJC_01243 3.8e-179 rhaR K helix_turn_helix, arabinose operon control protein
KHDCFEJC_01244 1.2e-241 iolF EGP Major facilitator Superfamily
KHDCFEJC_01245 1.8e-286 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KHDCFEJC_01246 1.4e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KHDCFEJC_01247 1.3e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
KHDCFEJC_01248 4.6e-165 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
KHDCFEJC_01249 1.7e-125 S Membrane
KHDCFEJC_01250 9.3e-71 yueI S Protein of unknown function (DUF1694)
KHDCFEJC_01251 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHDCFEJC_01252 8.7e-72 K Transcriptional regulator
KHDCFEJC_01253 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHDCFEJC_01254 4e-201 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KHDCFEJC_01256 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KHDCFEJC_01257 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHDCFEJC_01258 4.3e-80 rmaD K Transcriptional regulator
KHDCFEJC_01260 0.0 1.3.5.4 C FMN_bind
KHDCFEJC_01261 2.3e-170 K Transcriptional regulator
KHDCFEJC_01262 9.5e-95 K Helix-turn-helix domain
KHDCFEJC_01263 1.9e-130 K sequence-specific DNA binding
KHDCFEJC_01264 3.5e-88 S AAA domain
KHDCFEJC_01266 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
KHDCFEJC_01267 4.7e-91 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
KHDCFEJC_01268 2.4e-17
KHDCFEJC_01269 1.7e-88 L PFAM Integrase catalytic region
KHDCFEJC_01270 1.6e-25 L Helix-turn-helix domain
KHDCFEJC_01271 3.7e-49 N Uncharacterized conserved protein (DUF2075)
KHDCFEJC_01273 0.0 pepN 3.4.11.2 E aminopeptidase
KHDCFEJC_01274 1.9e-230 S PglZ domain
KHDCFEJC_01275 1.3e-168 V Type II restriction enzyme, methylase subunits
KHDCFEJC_01276 2.3e-148 L Belongs to the 'phage' integrase family
KHDCFEJC_01277 0.0 2.1.1.72 LV Eco57I restriction-modification methylase
KHDCFEJC_01278 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
KHDCFEJC_01279 4.1e-72 S Domain of unknown function (DUF1788)
KHDCFEJC_01280 2.2e-65 S Putative inner membrane protein (DUF1819)
KHDCFEJC_01281 7.3e-148 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KHDCFEJC_01282 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
KHDCFEJC_01283 4.2e-157 yjdB S Domain of unknown function (DUF4767)
KHDCFEJC_01284 3.5e-146 Q Fumarylacetoacetate (FAA) hydrolase family
KHDCFEJC_01285 5.3e-72 asp2 S Asp23 family, cell envelope-related function
KHDCFEJC_01286 8.7e-72 asp S Asp23 family, cell envelope-related function
KHDCFEJC_01287 7.2e-23
KHDCFEJC_01288 5.7e-84
KHDCFEJC_01289 7.1e-37 S Transglycosylase associated protein
KHDCFEJC_01290 0.0 XK27_09800 I Acyltransferase family
KHDCFEJC_01291 5.7e-38 S MORN repeat
KHDCFEJC_01292 1.9e-48
KHDCFEJC_01293 8.7e-153 S Domain of unknown function (DUF4767)
KHDCFEJC_01294 3.4e-66
KHDCFEJC_01295 2.6e-68 D nuclear chromosome segregation
KHDCFEJC_01296 2.9e-48 K Cro/C1-type HTH DNA-binding domain
KHDCFEJC_01297 2.7e-160 S Cysteine-rich secretory protein family
KHDCFEJC_01298 2.2e-109 XK27_07075 V CAAX protease self-immunity
KHDCFEJC_01299 5.1e-60 K Helix-turn-helix XRE-family like proteins
KHDCFEJC_01300 5.3e-49
KHDCFEJC_01301 1.4e-27 K Helix-turn-helix XRE-family like proteins
KHDCFEJC_01302 3.2e-137 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
KHDCFEJC_01303 4.3e-101 K Transcriptional regulator, AbiEi antitoxin
KHDCFEJC_01304 4e-79 L AAA domain
KHDCFEJC_01305 5.2e-28 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHDCFEJC_01307 3.6e-131 pstS P T5orf172
KHDCFEJC_01308 3.3e-291 yeeB L DEAD-like helicases superfamily
KHDCFEJC_01309 1.1e-41 yeeA V Type II restriction enzyme, methylase subunits
KHDCFEJC_01310 6e-284 yeeA V Type II restriction enzyme, methylase subunits
KHDCFEJC_01312 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KHDCFEJC_01313 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
KHDCFEJC_01314 1.1e-164 fabK 1.3.1.9 S Nitronate monooxygenase
KHDCFEJC_01315 0.0 helD 3.6.4.12 L DNA helicase
KHDCFEJC_01316 2.5e-110 dedA S SNARE associated Golgi protein
KHDCFEJC_01317 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
KHDCFEJC_01318 0.0 yjbQ P TrkA C-terminal domain protein
KHDCFEJC_01319 4.7e-125 pgm3 G Phosphoglycerate mutase family
KHDCFEJC_01320 5.5e-129 pgm3 G Phosphoglycerate mutase family
KHDCFEJC_01321 1.2e-26
KHDCFEJC_01322 5.5e-47 sugE U Multidrug resistance protein
KHDCFEJC_01323 2.9e-78 3.6.1.55 F NUDIX domain
KHDCFEJC_01324 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHDCFEJC_01325 7.1e-98 K Bacterial regulatory proteins, tetR family
KHDCFEJC_01326 3.8e-85 S membrane transporter protein
KHDCFEJC_01327 4.9e-210 EGP Major facilitator Superfamily
KHDCFEJC_01328 5.7e-71 K MarR family
KHDCFEJC_01329 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
KHDCFEJC_01330 1.6e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
KHDCFEJC_01331 1.1e-58 steT E amino acid
KHDCFEJC_01332 1.6e-67 steT E amino acid
KHDCFEJC_01333 1.2e-73 steT E amino acid
KHDCFEJC_01334 8.4e-142 G YdjC-like protein
KHDCFEJC_01335 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
KHDCFEJC_01336 1.4e-153 K CAT RNA binding domain
KHDCFEJC_01337 1e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHDCFEJC_01338 4e-108 glnP P ABC transporter permease
KHDCFEJC_01339 1.6e-109 gluC P ABC transporter permease
KHDCFEJC_01340 7.8e-149 glnH ET ABC transporter substrate-binding protein
KHDCFEJC_01341 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHDCFEJC_01343 2.3e-40
KHDCFEJC_01344 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHDCFEJC_01345 7.8e-211 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KHDCFEJC_01346 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
KHDCFEJC_01347 4.9e-148
KHDCFEJC_01348 7.1e-12 3.2.1.14 GH18
KHDCFEJC_01349 1.3e-81 zur P Belongs to the Fur family
KHDCFEJC_01350 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
KHDCFEJC_01351 1.8e-19
KHDCFEJC_01352 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KHDCFEJC_01353 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KHDCFEJC_01354 1.6e-87
KHDCFEJC_01355 1.1e-251 yfnA E Amino Acid
KHDCFEJC_01356 2.2e-45
KHDCFEJC_01357 5e-69 O OsmC-like protein
KHDCFEJC_01358 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KHDCFEJC_01359 0.0 oatA I Acyltransferase
KHDCFEJC_01360 7.7e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KHDCFEJC_01361 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KHDCFEJC_01362 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHDCFEJC_01363 2.6e-152 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KHDCFEJC_01364 8.8e-150 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHDCFEJC_01365 1.7e-179 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHDCFEJC_01366 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KHDCFEJC_01367 1.1e-61 S Protein of unknown function (DUF3290)
KHDCFEJC_01368 1.3e-108 yviA S Protein of unknown function (DUF421)
KHDCFEJC_01369 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHDCFEJC_01370 5.1e-270 nox C NADH oxidase
KHDCFEJC_01371 4.1e-124 yliE T Putative diguanylate phosphodiesterase
KHDCFEJC_01372 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KHDCFEJC_01373 7.2e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KHDCFEJC_01374 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHDCFEJC_01375 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHDCFEJC_01376 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KHDCFEJC_01377 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
KHDCFEJC_01378 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
KHDCFEJC_01379 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHDCFEJC_01380 4.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHDCFEJC_01381 1.5e-155 pstA P Phosphate transport system permease protein PstA
KHDCFEJC_01382 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
KHDCFEJC_01383 2.1e-149 pstS P Phosphate
KHDCFEJC_01384 1.1e-246 phoR 2.7.13.3 T Histidine kinase
KHDCFEJC_01385 1.5e-132 K response regulator
KHDCFEJC_01386 2.1e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
KHDCFEJC_01387 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHDCFEJC_01388 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHDCFEJC_01389 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHDCFEJC_01390 7.5e-126 comFC S Competence protein
KHDCFEJC_01391 1.5e-258 comFA L Helicase C-terminal domain protein
KHDCFEJC_01392 1.7e-114 yvyE 3.4.13.9 S YigZ family
KHDCFEJC_01393 4.3e-145 pstS P Phosphate
KHDCFEJC_01394 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
KHDCFEJC_01395 0.0 ydaO E amino acid
KHDCFEJC_01396 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHDCFEJC_01397 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHDCFEJC_01398 6.1e-109 ydiL S CAAX protease self-immunity
KHDCFEJC_01399 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHDCFEJC_01400 1.1e-307 uup S ABC transporter, ATP-binding protein
KHDCFEJC_01401 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHDCFEJC_01402 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KHDCFEJC_01403 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KHDCFEJC_01404 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KHDCFEJC_01405 5.1e-190 phnD P Phosphonate ABC transporter
KHDCFEJC_01406 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KHDCFEJC_01407 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
KHDCFEJC_01408 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
KHDCFEJC_01409 1.4e-144 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
KHDCFEJC_01410 1.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
KHDCFEJC_01411 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KHDCFEJC_01412 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
KHDCFEJC_01413 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHDCFEJC_01414 1e-57 yabA L Involved in initiation control of chromosome replication
KHDCFEJC_01415 3.3e-186 holB 2.7.7.7 L DNA polymerase III
KHDCFEJC_01416 9.1e-50 yaaQ S Cyclic-di-AMP receptor
KHDCFEJC_01417 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHDCFEJC_01418 2.2e-38 yaaL S Protein of unknown function (DUF2508)
KHDCFEJC_01419 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHDCFEJC_01420 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHDCFEJC_01421 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHDCFEJC_01422 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHDCFEJC_01423 2.2e-108 rsmC 2.1.1.172 J Methyltransferase
KHDCFEJC_01424 6.5e-37 nrdH O Glutaredoxin
KHDCFEJC_01425 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHDCFEJC_01426 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHDCFEJC_01427 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
KHDCFEJC_01428 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHDCFEJC_01429 1.2e-38 L nuclease
KHDCFEJC_01430 9.3e-178 F DNA/RNA non-specific endonuclease
KHDCFEJC_01431 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHDCFEJC_01432 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHDCFEJC_01433 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHDCFEJC_01434 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHDCFEJC_01435 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
KHDCFEJC_01436 1.4e-98 nusG K Participates in transcription elongation, termination and antitermination
KHDCFEJC_01437 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHDCFEJC_01438 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KHDCFEJC_01439 9.1e-101 sigH K Sigma-70 region 2
KHDCFEJC_01440 1.2e-97 yacP S YacP-like NYN domain
KHDCFEJC_01441 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHDCFEJC_01442 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHDCFEJC_01443 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHDCFEJC_01444 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHDCFEJC_01445 3.7e-205 yacL S domain protein
KHDCFEJC_01446 1.7e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHDCFEJC_01447 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KHDCFEJC_01448 1.6e-51 HA62_12640 S GCN5-related N-acetyl-transferase
KHDCFEJC_01449 4.1e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHDCFEJC_01450 2.8e-257 pepC 3.4.22.40 E Peptidase C1-like family
KHDCFEJC_01451 1.7e-111 zmp2 O Zinc-dependent metalloprotease
KHDCFEJC_01452 4.7e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHDCFEJC_01453 1.7e-177 EG EamA-like transporter family
KHDCFEJC_01454 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KHDCFEJC_01455 2.4e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHDCFEJC_01456 7.7e-135 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
KHDCFEJC_01457 1.8e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHDCFEJC_01458 1.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
KHDCFEJC_01459 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
KHDCFEJC_01460 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHDCFEJC_01461 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
KHDCFEJC_01462 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
KHDCFEJC_01463 0.0 levR K Sigma-54 interaction domain
KHDCFEJC_01464 4.7e-64 S Domain of unknown function (DUF956)
KHDCFEJC_01465 4.4e-169 manN G system, mannose fructose sorbose family IID component
KHDCFEJC_01466 3.4e-133 manY G PTS system
KHDCFEJC_01467 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KHDCFEJC_01468 1.1e-152 G Peptidase_C39 like family
KHDCFEJC_01469 5e-80 ps461 M Glycosyl hydrolases family 25
KHDCFEJC_01472 1.6e-31
KHDCFEJC_01474 2.1e-71 S Protein of unknown function (DUF1617)
KHDCFEJC_01475 4.1e-141 sidC GT2,GT4 LM DNA recombination
KHDCFEJC_01476 1.8e-33 S Phage tail protein
KHDCFEJC_01477 3.8e-141 M Phage tail tape measure protein TP901
KHDCFEJC_01479 1.8e-38 S Phage tail tube protein
KHDCFEJC_01480 1.4e-21
KHDCFEJC_01481 1.7e-32
KHDCFEJC_01482 4.7e-24
KHDCFEJC_01483 9.8e-17
KHDCFEJC_01484 1.1e-113 S Phage capsid family
KHDCFEJC_01485 2.4e-56 clpP 3.4.21.92 OU Clp protease
KHDCFEJC_01486 3.6e-104 S Phage portal protein
KHDCFEJC_01487 9.7e-175 S Terminase
KHDCFEJC_01488 6.2e-13
KHDCFEJC_01493 2.9e-22
KHDCFEJC_01495 3e-10
KHDCFEJC_01497 3.4e-73 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KHDCFEJC_01498 4.2e-13
KHDCFEJC_01499 8.4e-38 S VRR_NUC
KHDCFEJC_01500 4.8e-134 S Virulence-associated protein E
KHDCFEJC_01501 1.2e-77 S Bifunctional DNA primase/polymerase, N-terminal
KHDCFEJC_01502 2.2e-26
KHDCFEJC_01503 1.3e-72 L AAA domain
KHDCFEJC_01504 2.4e-12 L HNH endonuclease
KHDCFEJC_01505 1.5e-162 S helicase activity
KHDCFEJC_01506 4e-41 S Siphovirus Gp157
KHDCFEJC_01513 1.7e-92 K ORF6N domain
KHDCFEJC_01514 7.9e-14 K Helix-turn-helix
KHDCFEJC_01515 1.6e-29 yvaO K Helix-turn-helix XRE-family like proteins
KHDCFEJC_01516 4.8e-17 E Pfam:DUF955
KHDCFEJC_01517 1.2e-13
KHDCFEJC_01519 2.3e-251 T PhoQ Sensor
KHDCFEJC_01520 1.3e-128 K Transcriptional regulatory protein, C terminal
KHDCFEJC_01521 1.8e-49
KHDCFEJC_01522 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
KHDCFEJC_01523 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_01524 9.9e-57
KHDCFEJC_01525 2.1e-41
KHDCFEJC_01526 1.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHDCFEJC_01527 2.9e-85 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
KHDCFEJC_01528 3.9e-26 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
KHDCFEJC_01529 1.6e-106 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
KHDCFEJC_01530 1.3e-47
KHDCFEJC_01531 2.7e-123 2.7.6.5 S RelA SpoT domain protein
KHDCFEJC_01532 3.1e-104 K transcriptional regulator
KHDCFEJC_01533 0.0 ydgH S MMPL family
KHDCFEJC_01534 1e-107 tag 3.2.2.20 L glycosylase
KHDCFEJC_01535 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
KHDCFEJC_01536 6.5e-183 yclI V MacB-like periplasmic core domain
KHDCFEJC_01537 7.1e-121 yclH V ABC transporter
KHDCFEJC_01538 2.5e-114 V CAAX protease self-immunity
KHDCFEJC_01539 1.3e-120 S CAAX protease self-immunity
KHDCFEJC_01540 1.7e-52 M Lysin motif
KHDCFEJC_01541 1.8e-52 lytE M LysM domain protein
KHDCFEJC_01542 7.4e-67 gcvH E Glycine cleavage H-protein
KHDCFEJC_01543 2.8e-176 sepS16B
KHDCFEJC_01544 3.7e-131
KHDCFEJC_01545 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
KHDCFEJC_01546 2.2e-55
KHDCFEJC_01547 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHDCFEJC_01548 6.5e-78 elaA S GNAT family
KHDCFEJC_01549 1.7e-75 K Transcriptional regulator
KHDCFEJC_01550 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
KHDCFEJC_01551 4.3e-40
KHDCFEJC_01552 4e-206 potD P ABC transporter
KHDCFEJC_01553 3.4e-141 potC P ABC transporter permease
KHDCFEJC_01554 2e-149 potB P ABC transporter permease
KHDCFEJC_01555 1.2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KHDCFEJC_01556 5e-96 puuR K Cupin domain
KHDCFEJC_01557 1.1e-83 6.3.3.2 S ASCH
KHDCFEJC_01558 1e-84 K GNAT family
KHDCFEJC_01559 1.8e-90 K acetyltransferase
KHDCFEJC_01560 8.1e-22
KHDCFEJC_01561 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
KHDCFEJC_01562 2e-163 ytrB V ABC transporter
KHDCFEJC_01563 4.9e-190
KHDCFEJC_01564 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
KHDCFEJC_01565 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KHDCFEJC_01567 3.4e-239 xylP1 G MFS/sugar transport protein
KHDCFEJC_01568 3e-122 qmcA O prohibitin homologues
KHDCFEJC_01569 1.5e-29
KHDCFEJC_01570 5e-281 pipD E Dipeptidase
KHDCFEJC_01571 3e-40
KHDCFEJC_01572 6.8e-96 bioY S BioY family
KHDCFEJC_01573 4.2e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KHDCFEJC_01574 2.8e-60 S CHY zinc finger
KHDCFEJC_01575 2.2e-111 metQ P NLPA lipoprotein
KHDCFEJC_01576 8.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHDCFEJC_01577 1.1e-86 metI U Binding-protein-dependent transport system inner membrane component
KHDCFEJC_01578 2.9e-147 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHDCFEJC_01579 2.2e-221 mtnE 2.6.1.83 E Aminotransferase
KHDCFEJC_01580 3.8e-218
KHDCFEJC_01581 3.5e-154 tagG U Transport permease protein
KHDCFEJC_01582 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KHDCFEJC_01583 8.4e-44
KHDCFEJC_01584 3.9e-93 K Transcriptional regulator PadR-like family
KHDCFEJC_01585 8.7e-257 P Major Facilitator Superfamily
KHDCFEJC_01586 4.7e-241 amtB P ammonium transporter
KHDCFEJC_01587 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KHDCFEJC_01588 3.7e-44
KHDCFEJC_01589 5.3e-101 zmp1 O Zinc-dependent metalloprotease
KHDCFEJC_01590 1.8e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KHDCFEJC_01591 5.4e-310 mco Q Multicopper oxidase
KHDCFEJC_01592 1.1e-54 ypaA S Protein of unknown function (DUF1304)
KHDCFEJC_01593 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
KHDCFEJC_01594 4.7e-232 flhF N Uncharacterized conserved protein (DUF2075)
KHDCFEJC_01595 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
KHDCFEJC_01596 7.1e-80
KHDCFEJC_01597 5.9e-60 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KHDCFEJC_01598 4.5e-174 rihC 3.2.2.1 F Nucleoside
KHDCFEJC_01599 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHDCFEJC_01600 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
KHDCFEJC_01601 4e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KHDCFEJC_01602 9.9e-180 proV E ABC transporter, ATP-binding protein
KHDCFEJC_01603 1.7e-254 gshR 1.8.1.7 C Glutathione reductase
KHDCFEJC_01604 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHDCFEJC_01605 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
KHDCFEJC_01606 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHDCFEJC_01607 2.9e-241 M domain protein
KHDCFEJC_01608 5e-52 U domain, Protein
KHDCFEJC_01609 4.4e-25 S Immunity protein 74
KHDCFEJC_01610 9.2e-127
KHDCFEJC_01611 2.8e-28
KHDCFEJC_01612 1.1e-65
KHDCFEJC_01613 2.1e-67 S Immunity protein 63
KHDCFEJC_01614 2.8e-23
KHDCFEJC_01615 4.9e-39
KHDCFEJC_01616 6.2e-119 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KHDCFEJC_01617 5.3e-196 uhpT EGP Major facilitator Superfamily
KHDCFEJC_01618 1e-48 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
KHDCFEJC_01619 5.3e-83 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
KHDCFEJC_01620 4.3e-166 K Transcriptional regulator
KHDCFEJC_01621 1.4e-150 S hydrolase
KHDCFEJC_01622 3.9e-254 brnQ U Component of the transport system for branched-chain amino acids
KHDCFEJC_01623 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KHDCFEJC_01625 4.5e-115
KHDCFEJC_01627 2.4e-69 S CAAX protease self-immunity
KHDCFEJC_01628 6.7e-119 ypbD S CAAX protease self-immunity
KHDCFEJC_01629 8.1e-112 V CAAX protease self-immunity
KHDCFEJC_01630 6.8e-99 S CAAX protease self-immunity
KHDCFEJC_01631 1.8e-30
KHDCFEJC_01632 0.0 helD 3.6.4.12 L DNA helicase
KHDCFEJC_01633 3.8e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KHDCFEJC_01634 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHDCFEJC_01635 9e-130 K UbiC transcription regulator-associated domain protein
KHDCFEJC_01636 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_01637 3.9e-24
KHDCFEJC_01638 2.6e-76 S Domain of unknown function (DUF3284)
KHDCFEJC_01639 1.5e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_01640 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_01641 2e-163 GK ROK family
KHDCFEJC_01642 1.6e-132 K Helix-turn-helix domain, rpiR family
KHDCFEJC_01643 4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHDCFEJC_01644 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KHDCFEJC_01645 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KHDCFEJC_01646 1.6e-177
KHDCFEJC_01647 3.9e-133 cobB K SIR2 family
KHDCFEJC_01648 2e-160 yunF F Protein of unknown function DUF72
KHDCFEJC_01649 2.6e-70 mutT 3.6.1.55 F DNA mismatch repair protein MutT
KHDCFEJC_01650 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHDCFEJC_01652 2.5e-209 bcr1 EGP Major facilitator Superfamily
KHDCFEJC_01653 1.1e-105 mutR K sequence-specific DNA binding
KHDCFEJC_01655 1.5e-146 tatD L hydrolase, TatD family
KHDCFEJC_01656 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHDCFEJC_01657 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHDCFEJC_01658 3.2e-37 veg S Biofilm formation stimulator VEG
KHDCFEJC_01659 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHDCFEJC_01660 1.3e-181 S Prolyl oligopeptidase family
KHDCFEJC_01661 9.8e-129 fhuC 3.6.3.35 P ABC transporter
KHDCFEJC_01662 9.2e-131 znuB U ABC 3 transport family
KHDCFEJC_01663 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
KHDCFEJC_01664 1.8e-12
KHDCFEJC_01665 8.7e-160 2.7.13.3 T GHKL domain
KHDCFEJC_01666 7.4e-135 K LytTr DNA-binding domain
KHDCFEJC_01667 4.9e-78 yneH 1.20.4.1 K ArsC family
KHDCFEJC_01668 3.5e-290 katA 1.11.1.6 C Belongs to the catalase family
KHDCFEJC_01669 9e-13 ytgB S Transglycosylase associated protein
KHDCFEJC_01670 3.6e-11
KHDCFEJC_01671 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
KHDCFEJC_01672 4.2e-70 S Pyrimidine dimer DNA glycosylase
KHDCFEJC_01673 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
KHDCFEJC_01674 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KHDCFEJC_01675 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KHDCFEJC_01676 5.2e-156 nanK GK ROK family
KHDCFEJC_01677 1.9e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
KHDCFEJC_01678 1.5e-206 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KHDCFEJC_01679 2.6e-272 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHDCFEJC_01680 7.5e-160 I alpha/beta hydrolase fold
KHDCFEJC_01681 2.9e-164 I alpha/beta hydrolase fold
KHDCFEJC_01682 1.4e-71 yueI S Protein of unknown function (DUF1694)
KHDCFEJC_01683 7.4e-136 K Helix-turn-helix domain, rpiR family
KHDCFEJC_01684 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KHDCFEJC_01685 7e-112 K DeoR C terminal sensor domain
KHDCFEJC_01686 5.6e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHDCFEJC_01687 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
KHDCFEJC_01688 5.5e-231 gatC G PTS system sugar-specific permease component
KHDCFEJC_01689 8.6e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
KHDCFEJC_01690 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
KHDCFEJC_01691 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHDCFEJC_01692 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHDCFEJC_01693 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
KHDCFEJC_01694 1.7e-238 ulaA 2.7.1.194 S PTS system sugar-specific permease component
KHDCFEJC_01695 2.2e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHDCFEJC_01696 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHDCFEJC_01697 1.5e-144 yxeH S hydrolase
KHDCFEJC_01698 1.1e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHDCFEJC_01700 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KHDCFEJC_01701 6.1e-271 G Major Facilitator
KHDCFEJC_01702 2.1e-174 K Transcriptional regulator, LacI family
KHDCFEJC_01703 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
KHDCFEJC_01704 3.8e-159 licT K CAT RNA binding domain
KHDCFEJC_01705 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
KHDCFEJC_01706 1.9e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_01707 7.5e-293 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_01708 5.1e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KHDCFEJC_01709 5.4e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KHDCFEJC_01710 7.1e-270 sacX 2.7.1.193, 2.7.1.211 G phosphotransferase system
KHDCFEJC_01711 1.6e-146 yleF K Helix-turn-helix domain, rpiR family
KHDCFEJC_01712 3.7e-79 ptsG 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHDCFEJC_01713 3.3e-74 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHDCFEJC_01714 1e-268 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
KHDCFEJC_01715 1e-223 malY 4.4.1.8 E Aminotransferase class I and II
KHDCFEJC_01716 0.0 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHDCFEJC_01717 1.3e-117 licT K CAT RNA binding domain
KHDCFEJC_01718 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
KHDCFEJC_01719 5.2e-209 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_01720 2.1e-72 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_01721 2.5e-50 K Helix-turn-helix domain, rpiR family
KHDCFEJC_01722 9.9e-224 hrsA 2.7.1.195, 2.7.1.202 GT Phosphotransferase System
KHDCFEJC_01723 2.7e-256 mngB 3.2.1.170 GH38 G Alpha mannosidase, middle domain
KHDCFEJC_01724 7.7e-91 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KHDCFEJC_01725 1.4e-309 1.3.99.33 C FAD binding domain
KHDCFEJC_01726 8.2e-218 2.7.13.3 T Histidine kinase
KHDCFEJC_01727 3.2e-117 K helix_turn_helix, arabinose operon control protein
KHDCFEJC_01728 1.1e-211 S Bacterial protein of unknown function (DUF871)
KHDCFEJC_01729 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
KHDCFEJC_01730 1e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KHDCFEJC_01731 2.4e-248 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_01732 6.2e-134 K UTRA domain
KHDCFEJC_01733 6.9e-155 estA S Putative esterase
KHDCFEJC_01734 7.6e-64
KHDCFEJC_01735 5.7e-201 EGP Major Facilitator Superfamily
KHDCFEJC_01736 4.7e-168 K Transcriptional regulator, LysR family
KHDCFEJC_01737 2.1e-165 G Xylose isomerase-like TIM barrel
KHDCFEJC_01738 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
KHDCFEJC_01739 9.4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHDCFEJC_01740 5e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHDCFEJC_01741 1.2e-219 ydiN EGP Major Facilitator Superfamily
KHDCFEJC_01742 9.2e-175 K Transcriptional regulator, LysR family
KHDCFEJC_01743 2.5e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHDCFEJC_01744 1.7e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KHDCFEJC_01745 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHDCFEJC_01746 0.0 1.3.5.4 C FAD binding domain
KHDCFEJC_01747 2.4e-65 S pyridoxamine 5-phosphate
KHDCFEJC_01748 6.3e-193 C Aldo keto reductase family protein
KHDCFEJC_01749 1.1e-173 galR K Transcriptional regulator
KHDCFEJC_01750 1.3e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KHDCFEJC_01751 0.0 lacS G Transporter
KHDCFEJC_01752 0.0 rafA 3.2.1.22 G alpha-galactosidase
KHDCFEJC_01753 1e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KHDCFEJC_01754 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KHDCFEJC_01755 7.8e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHDCFEJC_01756 8.9e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KHDCFEJC_01757 1.3e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KHDCFEJC_01758 7.5e-183 galR K Transcriptional regulator
KHDCFEJC_01759 1.6e-76 K Helix-turn-helix XRE-family like proteins
KHDCFEJC_01760 3.5e-111 fic D Fic/DOC family
KHDCFEJC_01761 2.2e-182 rhaR K helix_turn_helix, arabinose operon control protein
KHDCFEJC_01762 9.5e-231 EGP Major facilitator Superfamily
KHDCFEJC_01763 1.1e-302 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KHDCFEJC_01764 1.2e-230 mdtH P Sugar (and other) transporter
KHDCFEJC_01765 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KHDCFEJC_01766 3e-187 lacR K Transcriptional regulator
KHDCFEJC_01767 0.0 lacA 3.2.1.23 G -beta-galactosidase
KHDCFEJC_01768 0.0 lacS G Transporter
KHDCFEJC_01769 1.3e-249 brnQ U Component of the transport system for branched-chain amino acids
KHDCFEJC_01770 0.0 ubiB S ABC1 family
KHDCFEJC_01771 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
KHDCFEJC_01772 1.6e-219 3.1.3.1 S associated with various cellular activities
KHDCFEJC_01773 5.2e-248 S Putative metallopeptidase domain
KHDCFEJC_01774 1.5e-49
KHDCFEJC_01775 5.4e-104 K Bacterial regulatory proteins, tetR family
KHDCFEJC_01776 4.6e-45
KHDCFEJC_01777 2.3e-99 S WxL domain surface cell wall-binding
KHDCFEJC_01778 1.5e-118 S WxL domain surface cell wall-binding
KHDCFEJC_01779 2.9e-152 S Cell surface protein
KHDCFEJC_01780 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
KHDCFEJC_01781 1.3e-262 nox C NADH oxidase
KHDCFEJC_01782 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHDCFEJC_01783 0.0 pepO 3.4.24.71 O Peptidase family M13
KHDCFEJC_01784 4.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KHDCFEJC_01785 1.6e-32 copZ P Heavy-metal-associated domain
KHDCFEJC_01786 2.5e-95 dps P Belongs to the Dps family
KHDCFEJC_01787 1.2e-18
KHDCFEJC_01788 9.5e-40 yrkD S Metal-sensitive transcriptional repressor
KHDCFEJC_01789 1.5e-55 txlA O Thioredoxin-like domain
KHDCFEJC_01790 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHDCFEJC_01791 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
KHDCFEJC_01792 6.2e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
KHDCFEJC_01793 2.4e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
KHDCFEJC_01794 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KHDCFEJC_01795 1.2e-182 yfeX P Peroxidase
KHDCFEJC_01796 2.7e-100 K transcriptional regulator
KHDCFEJC_01797 6.2e-120 4.1.1.46 S Amidohydrolase
KHDCFEJC_01798 1.3e-53 S Uncharacterized protein conserved in bacteria (DUF2316)
KHDCFEJC_01799 4e-107
KHDCFEJC_01800 1.3e-11 K Cro/C1-type HTH DNA-binding domain
KHDCFEJC_01802 2.8e-65 XK27_09885 V VanZ like family
KHDCFEJC_01803 8.6e-13
KHDCFEJC_01805 4.2e-62
KHDCFEJC_01806 2.5e-53
KHDCFEJC_01807 9.7e-72 mltD CBM50 M PFAM NLP P60 protein
KHDCFEJC_01808 5e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
KHDCFEJC_01809 1.8e-27
KHDCFEJC_01810 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KHDCFEJC_01811 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
KHDCFEJC_01812 3.5e-88 K Winged helix DNA-binding domain
KHDCFEJC_01814 7e-40
KHDCFEJC_01816 1.9e-248 EGP Major facilitator Superfamily
KHDCFEJC_01817 1.9e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
KHDCFEJC_01818 4.7e-83 cvpA S Colicin V production protein
KHDCFEJC_01819 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHDCFEJC_01820 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KHDCFEJC_01821 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
KHDCFEJC_01822 6.5e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KHDCFEJC_01823 6.7e-99 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
KHDCFEJC_01824 6.8e-212 folP 2.5.1.15 H dihydropteroate synthase
KHDCFEJC_01825 6.5e-96 tag 3.2.2.20 L glycosylase
KHDCFEJC_01826 2.6e-19
KHDCFEJC_01827 2.7e-160 czcD P cation diffusion facilitator family transporter
KHDCFEJC_01828 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
KHDCFEJC_01829 3e-116 hly S protein, hemolysin III
KHDCFEJC_01830 1.1e-44 qacH U Small Multidrug Resistance protein
KHDCFEJC_01831 4.4e-59 qacC P Small Multidrug Resistance protein
KHDCFEJC_01832 7.6e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
KHDCFEJC_01833 3.1e-179 K AI-2E family transporter
KHDCFEJC_01834 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHDCFEJC_01835 0.0 kup P Transport of potassium into the cell
KHDCFEJC_01837 1.5e-256 yhdG E C-terminus of AA_permease
KHDCFEJC_01838 4.3e-83
KHDCFEJC_01840 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHDCFEJC_01841 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
KHDCFEJC_01842 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHDCFEJC_01843 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHDCFEJC_01844 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHDCFEJC_01845 3.4e-55 S Enterocin A Immunity
KHDCFEJC_01846 2.8e-257 gor 1.8.1.7 C Glutathione reductase
KHDCFEJC_01847 1.6e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KHDCFEJC_01848 1.7e-184 D Alpha beta
KHDCFEJC_01849 4.8e-165 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
KHDCFEJC_01850 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
KHDCFEJC_01851 2.9e-117 yugP S Putative neutral zinc metallopeptidase
KHDCFEJC_01852 4.1e-25
KHDCFEJC_01853 2.5e-145 DegV S EDD domain protein, DegV family
KHDCFEJC_01854 7.3e-127 lrgB M LrgB-like family
KHDCFEJC_01855 1.2e-62 lrgA S LrgA family
KHDCFEJC_01856 3.8e-104 J Acetyltransferase (GNAT) domain
KHDCFEJC_01857 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
KHDCFEJC_01858 5.4e-36 S Phospholipase_D-nuclease N-terminal
KHDCFEJC_01859 7.1e-59 S Enterocin A Immunity
KHDCFEJC_01860 9.8e-88 perR P Belongs to the Fur family
KHDCFEJC_01861 6.9e-107
KHDCFEJC_01862 2.3e-237 S module of peptide synthetase
KHDCFEJC_01863 2e-100 S NADPH-dependent FMN reductase
KHDCFEJC_01864 1.4e-08
KHDCFEJC_01865 1.1e-126 magIII L Base excision DNA repair protein, HhH-GPD family
KHDCFEJC_01866 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
KHDCFEJC_01867 3.8e-154 1.6.5.2 GM NmrA-like family
KHDCFEJC_01868 2e-77 merR K MerR family regulatory protein
KHDCFEJC_01869 6.4e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHDCFEJC_01870 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KHDCFEJC_01871 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
KHDCFEJC_01872 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
KHDCFEJC_01873 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
KHDCFEJC_01874 1.1e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KHDCFEJC_01875 1.1e-147 cof S haloacid dehalogenase-like hydrolase
KHDCFEJC_01876 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
KHDCFEJC_01877 9.4e-77
KHDCFEJC_01878 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHDCFEJC_01879 9.4e-118 ybbL S ABC transporter, ATP-binding protein
KHDCFEJC_01880 2e-127 ybbM S Uncharacterised protein family (UPF0014)
KHDCFEJC_01881 1.3e-204 S DUF218 domain
KHDCFEJC_01882 1.4e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
KHDCFEJC_01883 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
KHDCFEJC_01884 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
KHDCFEJC_01885 1.6e-126 S Putative adhesin
KHDCFEJC_01886 1e-71 XK27_06920 S Protein of unknown function (DUF1700)
KHDCFEJC_01887 1.1e-50 K Transcriptional regulator
KHDCFEJC_01888 5.8e-79 KT response to antibiotic
KHDCFEJC_01889 1.2e-117 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KHDCFEJC_01890 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHDCFEJC_01891 9e-122 tcyB E ABC transporter
KHDCFEJC_01892 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KHDCFEJC_01893 1.9e-236 EK Aminotransferase, class I
KHDCFEJC_01894 2.1e-168 K LysR substrate binding domain
KHDCFEJC_01895 1.5e-147 S Alpha/beta hydrolase of unknown function (DUF915)
KHDCFEJC_01896 4.1e-226 nupG F Nucleoside
KHDCFEJC_01897 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KHDCFEJC_01898 2.7e-149 noc K Belongs to the ParB family
KHDCFEJC_01899 1.8e-136 soj D Sporulation initiation inhibitor
KHDCFEJC_01900 4.8e-157 spo0J K Belongs to the ParB family
KHDCFEJC_01901 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
KHDCFEJC_01902 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHDCFEJC_01903 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
KHDCFEJC_01904 6.8e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHDCFEJC_01905 3.4e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHDCFEJC_01906 1e-122 yoaK S Protein of unknown function (DUF1275)
KHDCFEJC_01907 3.2e-124 K response regulator
KHDCFEJC_01908 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
KHDCFEJC_01909 6.4e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KHDCFEJC_01910 1.2e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KHDCFEJC_01911 1.1e-130 azlC E branched-chain amino acid
KHDCFEJC_01912 2.3e-54 azlD S branched-chain amino acid
KHDCFEJC_01913 3.6e-110 S membrane transporter protein
KHDCFEJC_01914 4.1e-54
KHDCFEJC_01915 1.5e-74 S Psort location Cytoplasmic, score
KHDCFEJC_01916 1.7e-96 S Domain of unknown function (DUF4352)
KHDCFEJC_01917 6.8e-25 S Protein of unknown function (DUF4064)
KHDCFEJC_01918 9.1e-203 KLT Protein tyrosine kinase
KHDCFEJC_01919 1.7e-160
KHDCFEJC_01920 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KHDCFEJC_01921 2.4e-83
KHDCFEJC_01922 2.9e-210 xylR GK ROK family
KHDCFEJC_01923 5.4e-171 K AI-2E family transporter
KHDCFEJC_01924 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHDCFEJC_01925 8.8e-40
KHDCFEJC_01927 5.5e-38 L transposase activity
KHDCFEJC_01928 5.3e-104 K Bacterial regulatory proteins, tetR family
KHDCFEJC_01929 7.1e-19 S Domain of unknown function (DUF4440)
KHDCFEJC_01930 4e-254 qacA EGP Fungal trichothecene efflux pump (TRI12)
KHDCFEJC_01931 3.2e-77 3.5.4.1 GM SnoaL-like domain
KHDCFEJC_01932 9.7e-109 GM NAD(P)H-binding
KHDCFEJC_01933 5.9e-112 akr5f 1.1.1.346 S reductase
KHDCFEJC_01934 1.3e-103 M ErfK YbiS YcfS YnhG
KHDCFEJC_01935 4.2e-71 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHDCFEJC_01936 5e-83 3.2.1.17, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHDCFEJC_01937 6.5e-204 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KHDCFEJC_01938 9.3e-95 C Alcohol dehydrogenase GroES-like domain
KHDCFEJC_01939 7.2e-42 C Alcohol dehydrogenase GroES-like domain
KHDCFEJC_01940 1.5e-42 K HxlR-like helix-turn-helix
KHDCFEJC_01941 1e-107 ydeA S intracellular protease amidase
KHDCFEJC_01942 1.1e-43 S Protein of unknown function (DUF3781)
KHDCFEJC_01943 4.2e-207 S Membrane
KHDCFEJC_01944 7.6e-64 S Protein of unknown function (DUF1093)
KHDCFEJC_01945 2.2e-23 rmeD K helix_turn_helix, mercury resistance
KHDCFEJC_01946 9.4e-41 4.1.1.44 S Carboxymuconolactone decarboxylase family
KHDCFEJC_01947 1.5e-11
KHDCFEJC_01948 4.1e-65
KHDCFEJC_01949 2e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_01950 4.4e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_01951 2.2e-115 K UTRA
KHDCFEJC_01952 1.7e-84 dps P Belongs to the Dps family
KHDCFEJC_01953 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
KHDCFEJC_01954 1.6e-282 1.3.5.4 C FAD binding domain
KHDCFEJC_01955 3.3e-161 K LysR substrate binding domain
KHDCFEJC_01956 1.5e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
KHDCFEJC_01957 1.7e-290 yjcE P Sodium proton antiporter
KHDCFEJC_01958 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHDCFEJC_01959 8.1e-117 K Bacterial regulatory proteins, tetR family
KHDCFEJC_01960 9e-184 NU Mycoplasma protein of unknown function, DUF285
KHDCFEJC_01961 1.4e-38 S WxL domain surface cell wall-binding
KHDCFEJC_01962 5e-28 S WxL domain surface cell wall-binding
KHDCFEJC_01963 2.5e-173 S Bacterial protein of unknown function (DUF916)
KHDCFEJC_01964 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
KHDCFEJC_01965 1.3e-63 K helix_turn_helix, mercury resistance
KHDCFEJC_01966 7.5e-152 IQ Enoyl-(Acyl carrier protein) reductase
KHDCFEJC_01967 1.3e-68 maa S transferase hexapeptide repeat
KHDCFEJC_01968 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHDCFEJC_01969 7.7e-163 GM NmrA-like family
KHDCFEJC_01970 5.4e-92 K Bacterial regulatory proteins, tetR family
KHDCFEJC_01971 1.6e-98 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHDCFEJC_01972 5.5e-63 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHDCFEJC_01973 3.6e-177 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHDCFEJC_01974 1.1e-144 fhuC 3.6.3.34 HP ABC transporter
KHDCFEJC_01975 7.5e-169 fhuD P Periplasmic binding protein
KHDCFEJC_01976 7.4e-109 K Bacterial regulatory proteins, tetR family
KHDCFEJC_01977 1.6e-253 yfjF U Sugar (and other) transporter
KHDCFEJC_01980 1.5e-180 S Aldo keto reductase
KHDCFEJC_01981 1.6e-100 S Protein of unknown function (DUF1211)
KHDCFEJC_01982 1.2e-191 1.1.1.219 GM Male sterility protein
KHDCFEJC_01983 7.5e-95 K Bacterial regulatory proteins, tetR family
KHDCFEJC_01984 1.2e-115 ydfG S KR domain
KHDCFEJC_01985 1.4e-62 hxlR K HxlR-like helix-turn-helix
KHDCFEJC_01986 1e-47 S Domain of unknown function (DUF1905)
KHDCFEJC_01987 0.0 M Glycosyl hydrolases family 25
KHDCFEJC_01988 1.7e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KHDCFEJC_01989 1.8e-167 GM NmrA-like family
KHDCFEJC_01990 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
KHDCFEJC_01991 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHDCFEJC_01992 9.9e-95 K Bacterial regulatory proteins, tetR family
KHDCFEJC_01993 4.9e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
KHDCFEJC_01994 1.5e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KHDCFEJC_01995 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
KHDCFEJC_01996 1.7e-122 pnb C nitroreductase
KHDCFEJC_01997 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
KHDCFEJC_01998 1.8e-116 S Elongation factor G-binding protein, N-terminal
KHDCFEJC_01999 8.3e-134 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
KHDCFEJC_02000 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
KHDCFEJC_02001 3.5e-258 P Sodium:sulfate symporter transmembrane region
KHDCFEJC_02002 1.3e-157 K LysR family
KHDCFEJC_02003 1e-72 C FMN binding
KHDCFEJC_02004 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHDCFEJC_02005 2.3e-164 ptlF S KR domain
KHDCFEJC_02006 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
KHDCFEJC_02007 2.4e-121 drgA C Nitroreductase family
KHDCFEJC_02008 1.3e-290 QT PucR C-terminal helix-turn-helix domain
KHDCFEJC_02009 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KHDCFEJC_02010 5.1e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHDCFEJC_02011 1.4e-248 yjjP S Putative threonine/serine exporter
KHDCFEJC_02012 2.8e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
KHDCFEJC_02013 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
KHDCFEJC_02014 1.1e-80 6.3.3.2 S ASCH
KHDCFEJC_02015 5.5e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
KHDCFEJC_02016 5.5e-172 yobV1 K WYL domain
KHDCFEJC_02017 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHDCFEJC_02018 0.0 tetP J elongation factor G
KHDCFEJC_02019 1.1e-124 S Protein of unknown function
KHDCFEJC_02020 1.5e-150 EG EamA-like transporter family
KHDCFEJC_02021 2.2e-87 MA20_25245 K FR47-like protein
KHDCFEJC_02022 2e-126 hchA S DJ-1/PfpI family
KHDCFEJC_02023 2.7e-180 1.1.1.1 C nadph quinone reductase
KHDCFEJC_02024 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
KHDCFEJC_02025 2.3e-235 mepA V MATE efflux family protein
KHDCFEJC_02026 1.1e-166 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
KHDCFEJC_02027 1.3e-139 S Belongs to the UPF0246 family
KHDCFEJC_02028 6e-76
KHDCFEJC_02029 1.5e-280 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
KHDCFEJC_02030 9.1e-141
KHDCFEJC_02032 1.9e-118 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
KHDCFEJC_02033 4.8e-40
KHDCFEJC_02034 7.8e-129 cbiO P ABC transporter
KHDCFEJC_02035 2.6e-149 P Cobalt transport protein
KHDCFEJC_02036 4.8e-182 nikMN P PDGLE domain
KHDCFEJC_02037 4.2e-121 K Crp-like helix-turn-helix domain
KHDCFEJC_02038 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
KHDCFEJC_02039 5.3e-122 larB S AIR carboxylase
KHDCFEJC_02040 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KHDCFEJC_02041 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
KHDCFEJC_02042 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHDCFEJC_02043 4.1e-150 larE S NAD synthase
KHDCFEJC_02044 5.1e-176 1.6.5.5 C Zinc-binding dehydrogenase
KHDCFEJC_02045 2.2e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KHDCFEJC_02046 9.1e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KHDCFEJC_02047 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KHDCFEJC_02048 3.8e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
KHDCFEJC_02049 5.1e-136 S peptidase C26
KHDCFEJC_02050 3.6e-304 L HIRAN domain
KHDCFEJC_02051 3.4e-85 F NUDIX domain
KHDCFEJC_02052 2.6e-250 yifK E Amino acid permease
KHDCFEJC_02053 5.2e-122
KHDCFEJC_02054 3.3e-149 ydjP I Alpha/beta hydrolase family
KHDCFEJC_02055 0.0 pacL1 P P-type ATPase
KHDCFEJC_02056 1.6e-28 KT PspC domain
KHDCFEJC_02057 6.7e-110 S NADPH-dependent FMN reductase
KHDCFEJC_02058 1.2e-74 papX3 K Transcriptional regulator
KHDCFEJC_02059 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
KHDCFEJC_02060 4.9e-81 S Protein of unknown function (DUF3021)
KHDCFEJC_02061 3e-75 K LytTr DNA-binding domain
KHDCFEJC_02062 4.7e-227 mdtG EGP Major facilitator Superfamily
KHDCFEJC_02063 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
KHDCFEJC_02064 3.1e-215 yeaN P Transporter, major facilitator family protein
KHDCFEJC_02066 5.8e-160 S reductase
KHDCFEJC_02067 1.2e-165 1.1.1.65 C Aldo keto reductase
KHDCFEJC_02068 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
KHDCFEJC_02069 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
KHDCFEJC_02070 5e-52
KHDCFEJC_02071 7.5e-259
KHDCFEJC_02072 4e-209 C Oxidoreductase
KHDCFEJC_02073 7.1e-150 cbiQ P cobalt transport
KHDCFEJC_02074 0.0 ykoD P ABC transporter, ATP-binding protein
KHDCFEJC_02075 2.5e-98 S UPF0397 protein
KHDCFEJC_02076 1.6e-129 K UbiC transcription regulator-associated domain protein
KHDCFEJC_02077 8.3e-54 K Transcriptional regulator PadR-like family
KHDCFEJC_02078 4.3e-141
KHDCFEJC_02079 2e-149
KHDCFEJC_02080 9.1e-89
KHDCFEJC_02081 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
KHDCFEJC_02082 7.4e-169 yjjC V ABC transporter
KHDCFEJC_02083 4.3e-297 M Exporter of polyketide antibiotics
KHDCFEJC_02084 1.1e-116 K Transcriptional regulator
KHDCFEJC_02085 3.8e-274 C Electron transfer flavoprotein FAD-binding domain
KHDCFEJC_02086 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
KHDCFEJC_02088 1.1e-92 K Bacterial regulatory proteins, tetR family
KHDCFEJC_02089 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KHDCFEJC_02090 7.3e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KHDCFEJC_02091 1.9e-101 dhaL 2.7.1.121 S Dak2
KHDCFEJC_02092 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
KHDCFEJC_02093 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHDCFEJC_02094 1e-190 malR K Transcriptional regulator, LacI family
KHDCFEJC_02095 2e-180 yvdE K helix_turn _helix lactose operon repressor
KHDCFEJC_02096 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
KHDCFEJC_02097 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
KHDCFEJC_02098 8.4e-227 malC P Binding-protein-dependent transport system inner membrane component
KHDCFEJC_02099 1.4e-161 malD P ABC transporter permease
KHDCFEJC_02100 5.3e-150 malA S maltodextrose utilization protein MalA
KHDCFEJC_02101 5e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
KHDCFEJC_02102 3.4e-208 msmK P Belongs to the ABC transporter superfamily
KHDCFEJC_02103 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KHDCFEJC_02104 0.0 3.2.1.96 G Glycosyl hydrolase family 85
KHDCFEJC_02105 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
KHDCFEJC_02106 1.8e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KHDCFEJC_02107 0.0 rafA 3.2.1.22 G alpha-galactosidase
KHDCFEJC_02108 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
KHDCFEJC_02109 1.4e-305 scrB 3.2.1.26 GH32 G invertase
KHDCFEJC_02110 9.1e-173 scrR K Transcriptional regulator, LacI family
KHDCFEJC_02111 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
KHDCFEJC_02112 6.5e-165 3.5.1.10 C nadph quinone reductase
KHDCFEJC_02113 1.1e-217 nhaC C Na H antiporter NhaC
KHDCFEJC_02114 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
KHDCFEJC_02115 2.9e-165 mleR K LysR substrate binding domain
KHDCFEJC_02116 0.0 3.6.4.13 M domain protein
KHDCFEJC_02118 2.1e-157 hipB K Helix-turn-helix
KHDCFEJC_02119 0.0 oppA E ABC transporter, substratebinding protein
KHDCFEJC_02120 3.5e-310 oppA E ABC transporter, substratebinding protein
KHDCFEJC_02121 1e-78 yiaC K Acetyltransferase (GNAT) domain
KHDCFEJC_02122 6.7e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHDCFEJC_02123 6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHDCFEJC_02124 3e-113 pgm1 G phosphoglycerate mutase
KHDCFEJC_02125 1e-179 yghZ C Aldo keto reductase family protein
KHDCFEJC_02126 4.9e-34
KHDCFEJC_02127 1.3e-60 S Domain of unknown function (DU1801)
KHDCFEJC_02128 5.4e-161 FbpA K Domain of unknown function (DUF814)
KHDCFEJC_02129 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHDCFEJC_02131 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHDCFEJC_02132 1.9e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHDCFEJC_02133 4.4e-259 S ATPases associated with a variety of cellular activities
KHDCFEJC_02134 3.1e-116 P cobalt transport
KHDCFEJC_02135 1.4e-259 P ABC transporter
KHDCFEJC_02136 3.1e-101 S ABC transporter permease
KHDCFEJC_02137 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KHDCFEJC_02138 1.4e-158 dkgB S reductase
KHDCFEJC_02139 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHDCFEJC_02140 1e-69
KHDCFEJC_02141 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHDCFEJC_02143 6.3e-276 pipD E Dipeptidase
KHDCFEJC_02144 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
KHDCFEJC_02145 0.0 mtlR K Mga helix-turn-helix domain
KHDCFEJC_02146 3.9e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_02147 9.5e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
KHDCFEJC_02148 2.1e-73
KHDCFEJC_02149 6.2e-57 trxA1 O Belongs to the thioredoxin family
KHDCFEJC_02150 2.5e-50
KHDCFEJC_02151 6.6e-96
KHDCFEJC_02152 2e-62
KHDCFEJC_02153 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
KHDCFEJC_02154 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
KHDCFEJC_02155 3.5e-97 yieF S NADPH-dependent FMN reductase
KHDCFEJC_02156 7.2e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
KHDCFEJC_02157 9.8e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KHDCFEJC_02158 1.9e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KHDCFEJC_02159 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
KHDCFEJC_02160 4.3e-141 pnuC H nicotinamide mononucleotide transporter
KHDCFEJC_02161 7.3e-43 S Protein of unknown function (DUF2089)
KHDCFEJC_02162 2.2e-42
KHDCFEJC_02163 3.5e-129 treR K UTRA
KHDCFEJC_02164 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
KHDCFEJC_02165 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
KHDCFEJC_02166 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
KHDCFEJC_02167 1.4e-144
KHDCFEJC_02168 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
KHDCFEJC_02169 1.6e-235 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
KHDCFEJC_02170 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHDCFEJC_02171 3.5e-144 S Psort location CytoplasmicMembrane, score
KHDCFEJC_02172 6.1e-269 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
KHDCFEJC_02173 9.1e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
KHDCFEJC_02174 4.2e-29
KHDCFEJC_02175 7.7e-94 ytqB 2.1.1.176 J Putative rRNA methylase
KHDCFEJC_02176 3.3e-123 3.6.1.27 I Acid phosphatase homologues
KHDCFEJC_02177 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHDCFEJC_02178 3e-301 ytgP S Polysaccharide biosynthesis protein
KHDCFEJC_02179 1.9e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KHDCFEJC_02180 8.3e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHDCFEJC_02181 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
KHDCFEJC_02182 4.1e-84 uspA T Belongs to the universal stress protein A family
KHDCFEJC_02183 1.8e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
KHDCFEJC_02184 3.4e-172 ugpA U Binding-protein-dependent transport system inner membrane component
KHDCFEJC_02185 1.1e-150 ugpE G ABC transporter permease
KHDCFEJC_02186 1.6e-260 ugpB G Bacterial extracellular solute-binding protein
KHDCFEJC_02187 5.4e-124 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHDCFEJC_02188 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
KHDCFEJC_02189 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHDCFEJC_02190 8.7e-179 XK27_06930 V domain protein
KHDCFEJC_02192 2.5e-127 V Transport permease protein
KHDCFEJC_02193 2.3e-156 V ABC transporter
KHDCFEJC_02194 1.5e-175 K LytTr DNA-binding domain
KHDCFEJC_02195 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHDCFEJC_02196 1.6e-64 K helix_turn_helix, mercury resistance
KHDCFEJC_02197 3.5e-117 GM NAD(P)H-binding
KHDCFEJC_02198 7.9e-158 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KHDCFEJC_02199 7.6e-149 S Sucrose-6F-phosphate phosphohydrolase
KHDCFEJC_02200 1.7e-108
KHDCFEJC_02201 8.5e-224 pltK 2.7.13.3 T GHKL domain
KHDCFEJC_02202 1.6e-137 pltR K LytTr DNA-binding domain
KHDCFEJC_02203 1e-54
KHDCFEJC_02204 2.5e-59
KHDCFEJC_02205 3e-114 S CAAX protease self-immunity
KHDCFEJC_02206 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
KHDCFEJC_02207 2.5e-89
KHDCFEJC_02208 2.5e-46
KHDCFEJC_02209 0.0 uvrA2 L ABC transporter
KHDCFEJC_02212 5.9e-52
KHDCFEJC_02213 3.5e-10
KHDCFEJC_02214 2.1e-180
KHDCFEJC_02215 1.9e-89 gtcA S Teichoic acid glycosylation protein
KHDCFEJC_02216 3.6e-58 S Protein of unknown function (DUF1516)
KHDCFEJC_02217 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KHDCFEJC_02218 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHDCFEJC_02219 6.8e-306 S Protein conserved in bacteria
KHDCFEJC_02220 9.7e-230 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
KHDCFEJC_02221 2.5e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
KHDCFEJC_02222 1.8e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
KHDCFEJC_02223 2.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
KHDCFEJC_02224 0.0 yfbS P Sodium:sulfate symporter transmembrane region
KHDCFEJC_02225 2.1e-244 dinF V MatE
KHDCFEJC_02226 1.9e-31
KHDCFEJC_02229 2.7e-79 elaA S Acetyltransferase (GNAT) domain
KHDCFEJC_02230 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KHDCFEJC_02231 2.7e-82
KHDCFEJC_02232 0.0 yhcA V MacB-like periplasmic core domain
KHDCFEJC_02233 7.6e-107
KHDCFEJC_02234 0.0 K PRD domain
KHDCFEJC_02235 2.4e-62 S Domain of unknown function (DUF3284)
KHDCFEJC_02236 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
KHDCFEJC_02237 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KHDCFEJC_02238 6.1e-220 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHDCFEJC_02239 1e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHDCFEJC_02240 9.5e-209 EGP Major facilitator Superfamily
KHDCFEJC_02241 2e-114 M ErfK YbiS YcfS YnhG
KHDCFEJC_02242 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHDCFEJC_02243 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
KHDCFEJC_02244 1.4e-102 argO S LysE type translocator
KHDCFEJC_02245 2.7e-213 arcT 2.6.1.1 E Aminotransferase
KHDCFEJC_02246 4.4e-77 argR K Regulates arginine biosynthesis genes
KHDCFEJC_02247 2.9e-12
KHDCFEJC_02248 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KHDCFEJC_02249 1e-54 yheA S Belongs to the UPF0342 family
KHDCFEJC_02250 3.7e-232 yhaO L Ser Thr phosphatase family protein
KHDCFEJC_02251 0.0 L AAA domain
KHDCFEJC_02252 7.1e-186 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHDCFEJC_02253 3.1e-212
KHDCFEJC_02254 4.9e-179 3.4.21.102 M Peptidase family S41
KHDCFEJC_02255 1.2e-177 K LysR substrate binding domain
KHDCFEJC_02256 5.2e-110 1.3.5.4 S NADPH-dependent FMN reductase
KHDCFEJC_02257 0.0 1.3.5.4 C FAD binding domain
KHDCFEJC_02258 6.5e-99
KHDCFEJC_02259 1.8e-75 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
KHDCFEJC_02260 3e-184 ykoT GT2 M Glycosyl transferase family 2
KHDCFEJC_02261 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHDCFEJC_02262 1.7e-19 S NUDIX domain
KHDCFEJC_02263 0.0 S membrane
KHDCFEJC_02264 6.4e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHDCFEJC_02265 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KHDCFEJC_02266 2.2e-221 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KHDCFEJC_02267 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KHDCFEJC_02268 9.3e-106 GBS0088 S Nucleotidyltransferase
KHDCFEJC_02269 1.4e-106
KHDCFEJC_02270 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KHDCFEJC_02271 2.4e-46 K Bacterial regulatory proteins, tetR family
KHDCFEJC_02272 1.5e-50 K Bacterial regulatory proteins, tetR family
KHDCFEJC_02273 4.7e-241 npr 1.11.1.1 C NADH oxidase
KHDCFEJC_02274 0.0
KHDCFEJC_02275 1e-60
KHDCFEJC_02276 1.4e-192 S Fn3-like domain
KHDCFEJC_02277 5.2e-103 S WxL domain surface cell wall-binding
KHDCFEJC_02278 3.5e-78 S WxL domain surface cell wall-binding
KHDCFEJC_02279 2.1e-118 draG 3.2.2.24 O ADP-ribosylglycohydrolase
KHDCFEJC_02280 1.5e-137 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHDCFEJC_02281 2e-42
KHDCFEJC_02282 9.9e-82 hit FG histidine triad
KHDCFEJC_02283 8.1e-134 ecsA V ABC transporter, ATP-binding protein
KHDCFEJC_02284 2.1e-224 ecsB U ABC transporter
KHDCFEJC_02285 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
KHDCFEJC_02286 2.6e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHDCFEJC_02287 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
KHDCFEJC_02288 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHDCFEJC_02289 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KHDCFEJC_02290 1.5e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KHDCFEJC_02291 7.9e-21 S Virus attachment protein p12 family
KHDCFEJC_02292 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KHDCFEJC_02293 1.3e-34 feoA P FeoA domain
KHDCFEJC_02294 4.2e-144 sufC O FeS assembly ATPase SufC
KHDCFEJC_02295 2.6e-244 sufD O FeS assembly protein SufD
KHDCFEJC_02296 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHDCFEJC_02297 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
KHDCFEJC_02298 1.4e-272 sufB O assembly protein SufB
KHDCFEJC_02299 3.2e-179 fecB P Periplasmic binding protein
KHDCFEJC_02300 1.3e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
KHDCFEJC_02301 6.4e-166 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHDCFEJC_02302 2.2e-81 fld C NrdI Flavodoxin like
KHDCFEJC_02303 4.5e-70 moaE 2.8.1.12 H MoaE protein
KHDCFEJC_02304 5.4e-34 moaD 2.8.1.12 H ThiS family
KHDCFEJC_02305 4.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KHDCFEJC_02306 2.5e-217 narK P Transporter, major facilitator family protein
KHDCFEJC_02307 8.8e-59 yitW S Iron-sulfur cluster assembly protein
KHDCFEJC_02308 8.1e-157 hipB K Helix-turn-helix
KHDCFEJC_02309 3.9e-162 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
KHDCFEJC_02310 1.5e-183
KHDCFEJC_02311 7.5e-49
KHDCFEJC_02312 6.1e-117 nreC K PFAM regulatory protein LuxR
KHDCFEJC_02313 8.6e-190 comP 2.7.13.3 F Sensor histidine kinase
KHDCFEJC_02314 3.9e-75 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
KHDCFEJC_02315 7.8e-39
KHDCFEJC_02316 2.5e-99 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KHDCFEJC_02317 7.2e-86 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KHDCFEJC_02318 1.8e-89 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KHDCFEJC_02319 4.1e-231 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
KHDCFEJC_02320 1.6e-82 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KHDCFEJC_02321 3.2e-192 moeB 2.7.7.73, 2.7.7.80 H ThiF family
KHDCFEJC_02322 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KHDCFEJC_02323 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
KHDCFEJC_02324 7.3e-98 narJ C Nitrate reductase delta subunit
KHDCFEJC_02325 2.7e-123 narI 1.7.5.1 C Nitrate reductase
KHDCFEJC_02326 3.3e-175
KHDCFEJC_02327 1.5e-73
KHDCFEJC_02328 2.3e-96 S Protein of unknown function (DUF2975)
KHDCFEJC_02329 1.7e-28 yozG K Transcriptional regulator
KHDCFEJC_02330 4.5e-121 ybhL S Belongs to the BI1 family
KHDCFEJC_02331 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHDCFEJC_02332 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KHDCFEJC_02333 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHDCFEJC_02334 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHDCFEJC_02335 1.1e-248 dnaB L replication initiation and membrane attachment
KHDCFEJC_02336 3.3e-172 dnaI L Primosomal protein DnaI
KHDCFEJC_02337 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHDCFEJC_02338 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHDCFEJC_02339 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KHDCFEJC_02340 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHDCFEJC_02341 8.8e-39
KHDCFEJC_02342 1.4e-239 yrvN L AAA C-terminal domain
KHDCFEJC_02343 6.1e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KHDCFEJC_02344 1e-62 hxlR K Transcriptional regulator, HxlR family
KHDCFEJC_02345 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
KHDCFEJC_02346 1.4e-250 pgaC GT2 M Glycosyl transferase
KHDCFEJC_02347 1.4e-98 yqeG S HAD phosphatase, family IIIA
KHDCFEJC_02348 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
KHDCFEJC_02349 1.1e-50 yhbY J RNA-binding protein
KHDCFEJC_02350 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHDCFEJC_02351 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KHDCFEJC_02352 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHDCFEJC_02353 4.4e-140 yqeM Q Methyltransferase
KHDCFEJC_02354 2.2e-218 ylbM S Belongs to the UPF0348 family
KHDCFEJC_02355 6e-97 yceD S Uncharacterized ACR, COG1399
KHDCFEJC_02356 2.2e-89 S Peptidase propeptide and YPEB domain
KHDCFEJC_02357 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHDCFEJC_02358 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHDCFEJC_02359 4.2e-245 rarA L recombination factor protein RarA
KHDCFEJC_02360 4.3e-121 K response regulator
KHDCFEJC_02361 1.5e-305 arlS 2.7.13.3 T Histidine kinase
KHDCFEJC_02362 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KHDCFEJC_02363 0.0 sbcC L Putative exonuclease SbcCD, C subunit
KHDCFEJC_02364 4.5e-227 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KHDCFEJC_02365 8.4e-94 S SdpI/YhfL protein family
KHDCFEJC_02366 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHDCFEJC_02367 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KHDCFEJC_02368 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHDCFEJC_02369 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHDCFEJC_02370 7.4e-64 yodB K Transcriptional regulator, HxlR family
KHDCFEJC_02371 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHDCFEJC_02372 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHDCFEJC_02373 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHDCFEJC_02374 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
KHDCFEJC_02375 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHDCFEJC_02376 3.6e-94 liaI S membrane
KHDCFEJC_02377 3.4e-74 XK27_02470 K LytTr DNA-binding domain
KHDCFEJC_02378 1.5e-54 yneR S Belongs to the HesB IscA family
KHDCFEJC_02379 0.0 S membrane
KHDCFEJC_02380 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KHDCFEJC_02381 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KHDCFEJC_02382 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHDCFEJC_02383 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
KHDCFEJC_02384 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
KHDCFEJC_02385 5.7e-180 glk 2.7.1.2 G Glucokinase
KHDCFEJC_02386 1.9e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
KHDCFEJC_02387 4.4e-68 yqhL P Rhodanese-like protein
KHDCFEJC_02388 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
KHDCFEJC_02389 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
KHDCFEJC_02390 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHDCFEJC_02391 4.6e-64 glnR K Transcriptional regulator
KHDCFEJC_02392 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
KHDCFEJC_02393 3.6e-160
KHDCFEJC_02394 1.2e-180
KHDCFEJC_02395 2.4e-98 dut S Protein conserved in bacteria
KHDCFEJC_02396 5.3e-56
KHDCFEJC_02397 1.7e-30
KHDCFEJC_02400 5.4e-19
KHDCFEJC_02401 1.8e-89 K Transcriptional regulator
KHDCFEJC_02402 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KHDCFEJC_02403 3.2e-53 ysxB J Cysteine protease Prp
KHDCFEJC_02404 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KHDCFEJC_02405 5.9e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KHDCFEJC_02406 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHDCFEJC_02407 3.5e-74 yqhY S Asp23 family, cell envelope-related function
KHDCFEJC_02408 1.5e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHDCFEJC_02409 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHDCFEJC_02410 1.1e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHDCFEJC_02411 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHDCFEJC_02412 6.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KHDCFEJC_02413 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KHDCFEJC_02414 7.4e-77 argR K Regulates arginine biosynthesis genes
KHDCFEJC_02415 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
KHDCFEJC_02416 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
KHDCFEJC_02417 1.2e-104 opuCB E ABC transporter permease
KHDCFEJC_02418 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KHDCFEJC_02419 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
KHDCFEJC_02420 4.5e-55
KHDCFEJC_02421 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KHDCFEJC_02422 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHDCFEJC_02423 1.2e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHDCFEJC_02424 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHDCFEJC_02425 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHDCFEJC_02426 2.1e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHDCFEJC_02427 1.7e-134 stp 3.1.3.16 T phosphatase
KHDCFEJC_02428 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KHDCFEJC_02429 3e-162 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KHDCFEJC_02430 8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KHDCFEJC_02431 1.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
KHDCFEJC_02432 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KHDCFEJC_02433 1.8e-57 asp S Asp23 family, cell envelope-related function
KHDCFEJC_02434 0.0 yloV S DAK2 domain fusion protein YloV
KHDCFEJC_02435 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHDCFEJC_02436 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KHDCFEJC_02437 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHDCFEJC_02438 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHDCFEJC_02439 0.0 smc D Required for chromosome condensation and partitioning
KHDCFEJC_02440 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHDCFEJC_02441 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHDCFEJC_02442 2.9e-220 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHDCFEJC_02443 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KHDCFEJC_02444 2.6e-39 ylqC S Belongs to the UPF0109 family
KHDCFEJC_02445 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHDCFEJC_02446 2.2e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KHDCFEJC_02447 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHDCFEJC_02448 1.4e-50
KHDCFEJC_02449 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
KHDCFEJC_02450 5.3e-86
KHDCFEJC_02451 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
KHDCFEJC_02452 4.5e-270 XK27_00765
KHDCFEJC_02454 1.9e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
KHDCFEJC_02455 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
KHDCFEJC_02456 2.7e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHDCFEJC_02457 2.9e-121 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KHDCFEJC_02458 1.6e-109 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KHDCFEJC_02459 2.3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KHDCFEJC_02460 8.7e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KHDCFEJC_02461 1.7e-96 entB 3.5.1.19 Q Isochorismatase family
KHDCFEJC_02462 2.6e-177 1.6.5.5 C Zinc-binding dehydrogenase
KHDCFEJC_02463 1.7e-66 ybbJ K Acetyltransferase (GNAT) family
KHDCFEJC_02464 5.8e-141 E glutamate:sodium symporter activity
KHDCFEJC_02465 5.4e-66 E glutamate:sodium symporter activity
KHDCFEJC_02466 2.6e-101 3.5.1.47 E Peptidase family M20/M25/M40
KHDCFEJC_02467 5.3e-101 3.5.1.47 E Peptidase family M20/M25/M40
KHDCFEJC_02468 2.7e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KHDCFEJC_02469 1e-223 lsgC M Glycosyl transferases group 1
KHDCFEJC_02470 3.3e-21 S Protein of unknown function (DUF2929)
KHDCFEJC_02471 1.7e-48 K Cro/C1-type HTH DNA-binding domain
KHDCFEJC_02472 6.6e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHDCFEJC_02473 1.6e-79 uspA T universal stress protein
KHDCFEJC_02474 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
KHDCFEJC_02475 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
KHDCFEJC_02476 4e-60
KHDCFEJC_02477 1.7e-73
KHDCFEJC_02478 5e-82 yybC S Protein of unknown function (DUF2798)
KHDCFEJC_02479 6.3e-45
KHDCFEJC_02480 5.2e-47
KHDCFEJC_02481 4.2e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KHDCFEJC_02482 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
KHDCFEJC_02483 8.4e-145 yjfP S Dienelactone hydrolase family
KHDCFEJC_02484 2.7e-67
KHDCFEJC_02485 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHDCFEJC_02486 5.9e-48
KHDCFEJC_02487 3.9e-57
KHDCFEJC_02489 8.7e-164
KHDCFEJC_02490 1.3e-72 K Transcriptional regulator
KHDCFEJC_02491 0.0 pepF2 E Oligopeptidase F
KHDCFEJC_02492 4.5e-174 D Alpha beta
KHDCFEJC_02493 1.2e-45 S Enterocin A Immunity
KHDCFEJC_02494 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
KHDCFEJC_02495 5.1e-125 skfE V ABC transporter
KHDCFEJC_02496 2.7e-132
KHDCFEJC_02497 3.7e-107 pncA Q Isochorismatase family
KHDCFEJC_02498 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHDCFEJC_02499 0.0 yjcE P Sodium proton antiporter
KHDCFEJC_02500 5.5e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
KHDCFEJC_02501 6e-177 S Oxidoreductase family, NAD-binding Rossmann fold
KHDCFEJC_02502 8.1e-117 K Helix-turn-helix domain, rpiR family
KHDCFEJC_02503 2.3e-157 ccpB 5.1.1.1 K lacI family
KHDCFEJC_02504 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
KHDCFEJC_02505 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHDCFEJC_02506 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
KHDCFEJC_02507 1.2e-97 drgA C Nitroreductase family
KHDCFEJC_02508 1e-167 S Polyphosphate kinase 2 (PPK2)
KHDCFEJC_02509 2.6e-176 3.6.4.13 S domain, Protein
KHDCFEJC_02510 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
KHDCFEJC_02511 8.9e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KHDCFEJC_02512 6.7e-216 glpQ 3.1.4.46 C phosphodiesterase
KHDCFEJC_02513 1.6e-60 glpQ 3.1.4.46 C phosphodiesterase
KHDCFEJC_02514 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHDCFEJC_02515 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
KHDCFEJC_02516 2.1e-285 M domain protein
KHDCFEJC_02517 0.0 ydgH S MMPL family
KHDCFEJC_02518 3.2e-112 S Protein of unknown function (DUF1211)
KHDCFEJC_02519 3.1e-33
KHDCFEJC_02520 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHDCFEJC_02521 3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHDCFEJC_02522 4.3e-97 J glyoxalase III activity
KHDCFEJC_02523 1e-99 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
KHDCFEJC_02524 3.1e-37 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
KHDCFEJC_02525 5.9e-91 rmeB K transcriptional regulator, MerR family
KHDCFEJC_02526 2.1e-55 S Domain of unknown function (DU1801)
KHDCFEJC_02527 7.6e-166 corA P CorA-like Mg2+ transporter protein
KHDCFEJC_02528 4.6e-216 ysaA V RDD family
KHDCFEJC_02529 5e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
KHDCFEJC_02530 1.9e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KHDCFEJC_02531 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KHDCFEJC_02532 2.7e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHDCFEJC_02533 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KHDCFEJC_02534 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHDCFEJC_02535 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KHDCFEJC_02536 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KHDCFEJC_02537 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHDCFEJC_02538 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
KHDCFEJC_02539 1.9e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHDCFEJC_02540 2.4e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KHDCFEJC_02541 3.1e-136 terC P membrane
KHDCFEJC_02542 5.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
KHDCFEJC_02543 5.7e-258 npr 1.11.1.1 C NADH oxidase
KHDCFEJC_02544 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
KHDCFEJC_02545 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KHDCFEJC_02546 3.1e-176 XK27_08835 S ABC transporter
KHDCFEJC_02547 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KHDCFEJC_02548 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KHDCFEJC_02549 6.8e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
KHDCFEJC_02550 5e-162 degV S Uncharacterised protein, DegV family COG1307
KHDCFEJC_02551 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHDCFEJC_02552 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
KHDCFEJC_02553 6e-39
KHDCFEJC_02554 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHDCFEJC_02555 2e-106 3.2.2.20 K acetyltransferase
KHDCFEJC_02556 7.8e-296 S ABC transporter, ATP-binding protein
KHDCFEJC_02557 6.6e-218 2.7.7.65 T diguanylate cyclase
KHDCFEJC_02558 3.3e-33
KHDCFEJC_02559 7.6e-35
KHDCFEJC_02560 3.3e-80 K AsnC family
KHDCFEJC_02561 2.8e-173 ykfC 3.4.14.13 M NlpC/P60 family
KHDCFEJC_02562 5.9e-160 S Alpha/beta hydrolase of unknown function (DUF915)
KHDCFEJC_02564 3.8e-23
KHDCFEJC_02565 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
KHDCFEJC_02566 1.4e-212 yceI EGP Major facilitator Superfamily
KHDCFEJC_02567 8.6e-48
KHDCFEJC_02568 7.7e-92 S ECF-type riboflavin transporter, S component
KHDCFEJC_02570 1.5e-169 EG EamA-like transporter family
KHDCFEJC_02571 8.9e-38 gcvR T Belongs to the UPF0237 family
KHDCFEJC_02572 3e-243 XK27_08635 S UPF0210 protein
KHDCFEJC_02573 1.6e-134 K response regulator
KHDCFEJC_02574 2.9e-287 yclK 2.7.13.3 T Histidine kinase
KHDCFEJC_02575 3.2e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
KHDCFEJC_02576 9.7e-155 glcU U sugar transport
KHDCFEJC_02577 3.9e-259 pgi 5.3.1.9 G Belongs to the GPI family
KHDCFEJC_02578 6.8e-24
KHDCFEJC_02579 0.0 macB3 V ABC transporter, ATP-binding protein
KHDCFEJC_02580 4.5e-198 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KHDCFEJC_02581 2.3e-62 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KHDCFEJC_02582 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
KHDCFEJC_02583 1.6e-16
KHDCFEJC_02584 1.9e-18
KHDCFEJC_02585 1.1e-18
KHDCFEJC_02586 4.2e-18
KHDCFEJC_02587 2.1e-17
KHDCFEJC_02588 1.5e-14
KHDCFEJC_02589 4.7e-16
KHDCFEJC_02590 1.5e-14
KHDCFEJC_02591 3.1e-166 M MucBP domain
KHDCFEJC_02592 0.0 bztC D nuclear chromosome segregation
KHDCFEJC_02593 7.3e-83 K MarR family
KHDCFEJC_02594 3.2e-43
KHDCFEJC_02595 2e-38
KHDCFEJC_02597 8.9e-30
KHDCFEJC_02599 5.6e-219 int L Belongs to the 'phage' integrase family
KHDCFEJC_02600 5.8e-174 dam2 2.1.1.72 L DNA methyltransferase
KHDCFEJC_02601 0.0 S AAA ATPase domain
KHDCFEJC_02605 1.5e-181 S Type I restriction enzyme R protein N terminus (HSDR_N)
KHDCFEJC_02607 1.2e-09 S Pfam:Peptidase_M78
KHDCFEJC_02608 1.7e-16 K sequence-specific DNA binding
KHDCFEJC_02611 2.2e-53
KHDCFEJC_02612 4.4e-78
KHDCFEJC_02613 3.9e-15 S Domain of unknown function (DUF1508)
KHDCFEJC_02615 5.4e-55 S Bacteriophage Mu Gam like protein
KHDCFEJC_02616 4e-64
KHDCFEJC_02617 6.1e-147 3.1.3.16 L DnaD domain protein
KHDCFEJC_02618 7e-49
KHDCFEJC_02619 7.3e-89
KHDCFEJC_02620 7.1e-65 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KHDCFEJC_02622 1.5e-20 S YopX protein
KHDCFEJC_02623 2.4e-27
KHDCFEJC_02624 1.8e-14
KHDCFEJC_02626 2e-42 S Psort location Cytoplasmic, score
KHDCFEJC_02627 7.4e-47 S Beta protein
KHDCFEJC_02628 1.1e-27
KHDCFEJC_02629 1e-79 xtmA L Terminase small subunit
KHDCFEJC_02630 1.7e-262 S Phage terminase large subunit
KHDCFEJC_02631 1.2e-245 S Phage portal protein, SPP1 Gp6-like
KHDCFEJC_02632 2.7e-168 S Phage minor capsid protein 2
KHDCFEJC_02633 1.5e-45 S Phage minor structural protein GP20
KHDCFEJC_02634 8.3e-101
KHDCFEJC_02635 8.1e-09
KHDCFEJC_02636 1.4e-54 S Minor capsid protein
KHDCFEJC_02637 1e-49 S Minor capsid protein
KHDCFEJC_02638 1.6e-67 S Minor capsid protein from bacteriophage
KHDCFEJC_02639 3.4e-78
KHDCFEJC_02641 3.1e-102 S Bacteriophage Gp15 protein
KHDCFEJC_02642 0.0 S peptidoglycan catabolic process
KHDCFEJC_02643 9.6e-123 S Phage tail protein
KHDCFEJC_02644 6.9e-161 S Prophage endopeptidase tail
KHDCFEJC_02646 7.3e-59 cotH M CotH kinase protein
KHDCFEJC_02647 1.5e-177 M Glycosyl hydrolases family 25
KHDCFEJC_02648 5.2e-47
KHDCFEJC_02649 8e-24 hol S Bacteriophage holin
KHDCFEJC_02650 3.7e-20 T SpoVT / AbrB like domain
KHDCFEJC_02651 6.6e-22 chpA T Toxic component of a toxin-antitoxin (TA) module
KHDCFEJC_02653 3.8e-135 yxkH G Polysaccharide deacetylase
KHDCFEJC_02654 3.3e-65 S Protein of unknown function (DUF1093)
KHDCFEJC_02655 0.0 ycfI V ABC transporter, ATP-binding protein
KHDCFEJC_02656 0.0 yfiC V ABC transporter
KHDCFEJC_02657 7.4e-127
KHDCFEJC_02658 1.9e-58
KHDCFEJC_02659 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KHDCFEJC_02660 5.2e-29
KHDCFEJC_02661 5.9e-191 ampC V Beta-lactamase
KHDCFEJC_02662 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
KHDCFEJC_02663 5.9e-137 cobQ S glutamine amidotransferase
KHDCFEJC_02664 3.8e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
KHDCFEJC_02665 9.3e-109 tdk 2.7.1.21 F thymidine kinase
KHDCFEJC_02666 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHDCFEJC_02667 1.6e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHDCFEJC_02668 2.2e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KHDCFEJC_02669 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHDCFEJC_02670 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHDCFEJC_02671 1.1e-231 pyrP F Permease
KHDCFEJC_02672 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
KHDCFEJC_02673 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHDCFEJC_02674 1.8e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHDCFEJC_02675 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHDCFEJC_02676 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHDCFEJC_02677 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHDCFEJC_02678 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHDCFEJC_02679 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KHDCFEJC_02680 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHDCFEJC_02681 2.1e-102 J Acetyltransferase (GNAT) domain
KHDCFEJC_02682 1.7e-179 mbl D Cell shape determining protein MreB Mrl
KHDCFEJC_02683 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KHDCFEJC_02684 3.3e-33 S Protein of unknown function (DUF2969)
KHDCFEJC_02685 9.3e-220 rodA D Belongs to the SEDS family
KHDCFEJC_02686 3.6e-48 gcsH2 E glycine cleavage
KHDCFEJC_02687 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHDCFEJC_02688 1.7e-109 metI U ABC transporter permease
KHDCFEJC_02689 7e-142 metQ M Belongs to the nlpA lipoprotein family
KHDCFEJC_02690 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
KHDCFEJC_02691 1.6e-177 S Protein of unknown function (DUF2785)
KHDCFEJC_02692 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KHDCFEJC_02693 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KHDCFEJC_02694 1.5e-294 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KHDCFEJC_02695 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KHDCFEJC_02696 3.1e-201 bla2 3.5.2.6 V Beta-lactamase enzyme family
KHDCFEJC_02697 6.2e-82 usp6 T universal stress protein
KHDCFEJC_02698 1.5e-38
KHDCFEJC_02699 2.3e-237 rarA L recombination factor protein RarA
KHDCFEJC_02700 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KHDCFEJC_02701 5.9e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
KHDCFEJC_02702 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
KHDCFEJC_02703 1.8e-102 G PTS system sorbose-specific iic component
KHDCFEJC_02704 2.7e-104 G PTS system mannose fructose sorbose family IID component
KHDCFEJC_02705 9.2e-42 2.7.1.191 G PTS system fructose IIA component
KHDCFEJC_02706 5.1e-232 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KHDCFEJC_02707 1.7e-44 czrA K Helix-turn-helix domain
KHDCFEJC_02708 3.1e-110 S Protein of unknown function (DUF1648)
KHDCFEJC_02709 7.3e-80 yueI S Protein of unknown function (DUF1694)
KHDCFEJC_02710 3.3e-112 yktB S Belongs to the UPF0637 family
KHDCFEJC_02711 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHDCFEJC_02712 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
KHDCFEJC_02713 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KHDCFEJC_02714 3.2e-217 iscS2 2.8.1.7 E Aminotransferase class V
KHDCFEJC_02715 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHDCFEJC_02716 4e-234 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KHDCFEJC_02717 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KHDCFEJC_02718 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHDCFEJC_02719 5.8e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KHDCFEJC_02720 1.1e-53 radC L DNA repair protein
KHDCFEJC_02721 3e-53 radC L DNA repair protein
KHDCFEJC_02722 2.8e-161 mreB D cell shape determining protein MreB
KHDCFEJC_02723 5.8e-144 mreC M Involved in formation and maintenance of cell shape
KHDCFEJC_02724 3.6e-88 mreD M rod shape-determining protein MreD
KHDCFEJC_02725 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KHDCFEJC_02726 3.5e-146 minD D Belongs to the ParA family
KHDCFEJC_02727 4.6e-109 glnP P ABC transporter permease
KHDCFEJC_02728 7.4e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHDCFEJC_02729 1.5e-155 aatB ET ABC transporter substrate-binding protein
KHDCFEJC_02730 4.2e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
KHDCFEJC_02731 1.9e-231 ymfF S Peptidase M16 inactive domain protein
KHDCFEJC_02732 2.9e-251 ymfH S Peptidase M16
KHDCFEJC_02733 5.7e-110 ymfM S Helix-turn-helix domain
KHDCFEJC_02734 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHDCFEJC_02735 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
KHDCFEJC_02736 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHDCFEJC_02737 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
KHDCFEJC_02738 2.7e-154 ymdB S YmdB-like protein
KHDCFEJC_02739 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHDCFEJC_02740 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHDCFEJC_02741 1.3e-72
KHDCFEJC_02742 0.0 S Bacterial membrane protein YfhO
KHDCFEJC_02743 9.6e-89
KHDCFEJC_02744 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHDCFEJC_02745 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHDCFEJC_02746 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHDCFEJC_02747 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KHDCFEJC_02748 2.8e-29 yajC U Preprotein translocase
KHDCFEJC_02749 1.5e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHDCFEJC_02750 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KHDCFEJC_02751 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KHDCFEJC_02752 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHDCFEJC_02753 2.4e-43 yrzL S Belongs to the UPF0297 family
KHDCFEJC_02754 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHDCFEJC_02755 1.6e-48 yrzB S Belongs to the UPF0473 family
KHDCFEJC_02756 8e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KHDCFEJC_02757 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHDCFEJC_02758 3.3e-52 trxA O Belongs to the thioredoxin family
KHDCFEJC_02759 1.9e-92 yslB S Protein of unknown function (DUF2507)
KHDCFEJC_02760 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KHDCFEJC_02761 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHDCFEJC_02762 1.7e-93 S Phosphoesterase
KHDCFEJC_02763 6.5e-87 ykuL S (CBS) domain
KHDCFEJC_02764 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KHDCFEJC_02765 8.3e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KHDCFEJC_02766 2.6e-158 ykuT M mechanosensitive ion channel
KHDCFEJC_02767 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHDCFEJC_02768 2.8e-56
KHDCFEJC_02769 1.1e-80 K helix_turn_helix, mercury resistance
KHDCFEJC_02770 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KHDCFEJC_02771 1.9e-181 ccpA K catabolite control protein A
KHDCFEJC_02772 1.2e-163 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
KHDCFEJC_02773 3e-48 S DsrE/DsrF-like family
KHDCFEJC_02774 8.3e-131 yebC K Transcriptional regulatory protein
KHDCFEJC_02775 8.3e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHDCFEJC_02776 6.9e-173 comGA NU Type II IV secretion system protein
KHDCFEJC_02777 1.3e-188 comGB NU type II secretion system
KHDCFEJC_02778 5.5e-43 comGC U competence protein ComGC
KHDCFEJC_02779 3.2e-83 gspG NU general secretion pathway protein
KHDCFEJC_02780 8.6e-20
KHDCFEJC_02781 4.5e-88 S Prokaryotic N-terminal methylation motif
KHDCFEJC_02783 1.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
KHDCFEJC_02784 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHDCFEJC_02785 1.2e-252 cycA E Amino acid permease
KHDCFEJC_02786 4.4e-117 S Calcineurin-like phosphoesterase
KHDCFEJC_02787 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KHDCFEJC_02788 1.5e-80 yutD S Protein of unknown function (DUF1027)
KHDCFEJC_02789 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KHDCFEJC_02790 3.9e-116 S Protein of unknown function (DUF1461)
KHDCFEJC_02791 3e-119 dedA S SNARE-like domain protein
KHDCFEJC_02792 2.7e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHDCFEJC_02793 1.6e-75 yugI 5.3.1.9 J general stress protein
KHDCFEJC_02794 1.5e-62
KHDCFEJC_02795 3.6e-114 yjbH Q Thioredoxin
KHDCFEJC_02796 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
KHDCFEJC_02797 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHDCFEJC_02798 4.4e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KHDCFEJC_02799 5.1e-116 cutC P Participates in the control of copper homeostasis
KHDCFEJC_02800 7.4e-194 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KHDCFEJC_02801 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KHDCFEJC_02802 4.3e-206 XK27_05220 S AI-2E family transporter
KHDCFEJC_02803 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHDCFEJC_02804 1.8e-161 rrmA 2.1.1.187 H Methyltransferase
KHDCFEJC_02806 9.8e-210 brnQ U Component of the transport system for branched-chain amino acids
KHDCFEJC_02807 1.8e-113 ywnB S NAD(P)H-binding
KHDCFEJC_02808 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHDCFEJC_02809 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KHDCFEJC_02810 4.2e-175 corA P CorA-like Mg2+ transporter protein
KHDCFEJC_02811 1.9e-62 S Protein of unknown function (DUF3397)
KHDCFEJC_02812 1.9e-77 mraZ K Belongs to the MraZ family
KHDCFEJC_02813 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHDCFEJC_02814 1.1e-52 ftsL D Cell division protein FtsL
KHDCFEJC_02815 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KHDCFEJC_02816 2.4e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHDCFEJC_02817 3.6e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHDCFEJC_02818 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHDCFEJC_02819 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KHDCFEJC_02820 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KHDCFEJC_02821 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHDCFEJC_02822 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHDCFEJC_02823 1.2e-36 yggT S YGGT family
KHDCFEJC_02824 3.4e-146 ylmH S S4 domain protein
KHDCFEJC_02825 1.2e-86 divIVA D DivIVA domain protein
KHDCFEJC_02826 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHDCFEJC_02827 4.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KHDCFEJC_02828 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KHDCFEJC_02829 4.6e-28
KHDCFEJC_02830 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHDCFEJC_02831 1.6e-216 iscS 2.8.1.7 E Aminotransferase class V
KHDCFEJC_02832 4.9e-57 XK27_04120 S Putative amino acid metabolism
KHDCFEJC_02833 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KHDCFEJC_02834 1.3e-241 ktrB P Potassium uptake protein
KHDCFEJC_02835 2.6e-115 ktrA P domain protein
KHDCFEJC_02836 3.9e-120 N WxL domain surface cell wall-binding
KHDCFEJC_02837 1.7e-193 S Bacterial protein of unknown function (DUF916)
KHDCFEJC_02838 5.5e-267 N domain, Protein
KHDCFEJC_02839 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KHDCFEJC_02840 1.6e-120 S Repeat protein
KHDCFEJC_02841 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KHDCFEJC_02842 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHDCFEJC_02843 4.1e-108 mltD CBM50 M NlpC P60 family protein
KHDCFEJC_02844 1.7e-28
KHDCFEJC_02845 5.7e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KHDCFEJC_02846 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHDCFEJC_02847 3.1e-33 ykzG S Belongs to the UPF0356 family
KHDCFEJC_02848 1.6e-85
KHDCFEJC_02849 9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHDCFEJC_02850 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KHDCFEJC_02851 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KHDCFEJC_02852 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KHDCFEJC_02853 3.5e-266 lpdA 1.8.1.4 C Dehydrogenase
KHDCFEJC_02854 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
KHDCFEJC_02855 3.3e-46 yktA S Belongs to the UPF0223 family
KHDCFEJC_02856 1.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KHDCFEJC_02857 0.0 typA T GTP-binding protein TypA
KHDCFEJC_02858 1.9e-273
KHDCFEJC_02859 1.6e-205 ftsW D Belongs to the SEDS family
KHDCFEJC_02860 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KHDCFEJC_02861 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KHDCFEJC_02862 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KHDCFEJC_02863 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHDCFEJC_02864 9.6e-197 ylbL T Belongs to the peptidase S16 family
KHDCFEJC_02865 6.8e-125 comEA L Competence protein ComEA
KHDCFEJC_02866 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
KHDCFEJC_02867 0.0 comEC S Competence protein ComEC
KHDCFEJC_02868 2.4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
KHDCFEJC_02869 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
KHDCFEJC_02870 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHDCFEJC_02871 2e-190 mdtG EGP Major Facilitator Superfamily
KHDCFEJC_02872 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHDCFEJC_02873 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHDCFEJC_02874 1e-157 S Tetratricopeptide repeat
KHDCFEJC_02875 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHDCFEJC_02876 7.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHDCFEJC_02877 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHDCFEJC_02878 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KHDCFEJC_02879 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KHDCFEJC_02880 9.9e-73 S Iron-sulphur cluster biosynthesis
KHDCFEJC_02881 4.3e-22
KHDCFEJC_02882 9.2e-270 glnPH2 P ABC transporter permease
KHDCFEJC_02883 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHDCFEJC_02884 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHDCFEJC_02885 2.9e-126 epsB M biosynthesis protein
KHDCFEJC_02886 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KHDCFEJC_02887 1e-145 ywqE 3.1.3.48 GM PHP domain protein
KHDCFEJC_02888 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
KHDCFEJC_02889 1.8e-127 tuaA M Bacterial sugar transferase
KHDCFEJC_02890 6.1e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
KHDCFEJC_02891 2.9e-190 cps4G M Glycosyltransferase Family 4
KHDCFEJC_02892 1.1e-231
KHDCFEJC_02893 2.3e-176 cps4I M Glycosyltransferase like family 2
KHDCFEJC_02894 1.3e-260 cps4J S Polysaccharide biosynthesis protein
KHDCFEJC_02895 3.6e-137 cpdA S Calcineurin-like phosphoesterase
KHDCFEJC_02896 4.2e-72 cpdA S Calcineurin-like phosphoesterase
KHDCFEJC_02897 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
KHDCFEJC_02898 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KHDCFEJC_02899 1.5e-135 fruR K DeoR C terminal sensor domain
KHDCFEJC_02900 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHDCFEJC_02901 3.2e-46
KHDCFEJC_02902 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KHDCFEJC_02903 8.2e-140 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHDCFEJC_02904 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
KHDCFEJC_02905 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KHDCFEJC_02906 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHDCFEJC_02907 6.6e-99 K Helix-turn-helix domain
KHDCFEJC_02908 6.1e-211 EGP Major facilitator Superfamily
KHDCFEJC_02909 8.5e-57 ybjQ S Belongs to the UPF0145 family
KHDCFEJC_02910 1.1e-138 Q Methyltransferase
KHDCFEJC_02911 1.6e-31
KHDCFEJC_02913 1e-229 rodA D Cell cycle protein
KHDCFEJC_02914 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
KHDCFEJC_02915 6.9e-99 P ATPases associated with a variety of cellular activities
KHDCFEJC_02916 3.7e-31 P ATPases associated with a variety of cellular activities
KHDCFEJC_02917 2.1e-221 lytR5 K Cell envelope-related transcriptional attenuator domain
KHDCFEJC_02918 9.2e-101 L Helix-turn-helix domain
KHDCFEJC_02919 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
KHDCFEJC_02920 3.3e-65
KHDCFEJC_02921 2e-75
KHDCFEJC_02922 3.9e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KHDCFEJC_02923 3.7e-87
KHDCFEJC_02924 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHDCFEJC_02925 2.9e-36 ynzC S UPF0291 protein
KHDCFEJC_02926 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
KHDCFEJC_02927 1.2e-117 plsC 2.3.1.51 I Acyltransferase
KHDCFEJC_02928 9.3e-133 yabB 2.1.1.223 L Methyltransferase small domain
KHDCFEJC_02929 1.8e-39 yazA L GIY-YIG catalytic domain protein
KHDCFEJC_02930 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHDCFEJC_02931 4.7e-134 S Haloacid dehalogenase-like hydrolase
KHDCFEJC_02932 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
KHDCFEJC_02933 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHDCFEJC_02934 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KHDCFEJC_02935 5.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHDCFEJC_02936 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHDCFEJC_02937 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
KHDCFEJC_02938 6.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KHDCFEJC_02939 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHDCFEJC_02940 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHDCFEJC_02941 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
KHDCFEJC_02942 1.1e-217 nusA K Participates in both transcription termination and antitermination
KHDCFEJC_02943 9.5e-49 ylxR K Protein of unknown function (DUF448)
KHDCFEJC_02944 1.1e-47 ylxQ J ribosomal protein
KHDCFEJC_02945 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHDCFEJC_02946 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHDCFEJC_02947 2.5e-264 ydiN 5.4.99.5 G Major Facilitator
KHDCFEJC_02948 5.1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHDCFEJC_02949 2.9e-93
KHDCFEJC_02950 1.4e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KHDCFEJC_02951 6.5e-196 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KHDCFEJC_02952 2.1e-55 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHDCFEJC_02953 2.1e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHDCFEJC_02954 1.6e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KHDCFEJC_02955 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
KHDCFEJC_02956 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHDCFEJC_02957 1.6e-79 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHDCFEJC_02958 0.0 dnaK O Heat shock 70 kDa protein
KHDCFEJC_02959 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHDCFEJC_02960 3.7e-173 pbpX2 V Beta-lactamase
KHDCFEJC_02961 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
KHDCFEJC_02962 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHDCFEJC_02963 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
KHDCFEJC_02964 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHDCFEJC_02965 2.3e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHDCFEJC_02966 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHDCFEJC_02967 5.4e-49
KHDCFEJC_02968 1.4e-49
KHDCFEJC_02969 2e-36 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KHDCFEJC_02970 2.4e-65 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KHDCFEJC_02971 1e-176 prmA J Ribosomal protein L11 methyltransferase
KHDCFEJC_02972 5.4e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KHDCFEJC_02973 1.4e-56
KHDCFEJC_02974 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHDCFEJC_02975 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHDCFEJC_02976 2.2e-116 3.1.3.18 J HAD-hyrolase-like
KHDCFEJC_02977 1.5e-163 yniA G Fructosamine kinase
KHDCFEJC_02978 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KHDCFEJC_02979 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
KHDCFEJC_02980 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KHDCFEJC_02981 4.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHDCFEJC_02982 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHDCFEJC_02983 2.5e-222 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHDCFEJC_02984 4.5e-171 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KHDCFEJC_02985 5e-128 C Enoyl-(Acyl carrier protein) reductase
KHDCFEJC_02986 4.8e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KHDCFEJC_02987 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KHDCFEJC_02988 1.7e-70 yqeY S YqeY-like protein
KHDCFEJC_02989 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
KHDCFEJC_02990 1.6e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHDCFEJC_02991 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KHDCFEJC_02992 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHDCFEJC_02993 1.2e-146 recO L Involved in DNA repair and RecF pathway recombination
KHDCFEJC_02994 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KHDCFEJC_02995 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KHDCFEJC_02996 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHDCFEJC_02997 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHDCFEJC_02998 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
KHDCFEJC_02999 7e-164 ytrB V ABC transporter, ATP-binding protein
KHDCFEJC_03000 2e-202
KHDCFEJC_03001 3e-198
KHDCFEJC_03002 2.2e-126 S ABC-2 family transporter protein
KHDCFEJC_03003 1.5e-161 V ABC transporter, ATP-binding protein
KHDCFEJC_03004 5.8e-12 yjdF S Protein of unknown function (DUF2992)
KHDCFEJC_03005 6.5e-114 S Psort location CytoplasmicMembrane, score
KHDCFEJC_03006 2.6e-77 K MarR family
KHDCFEJC_03007 6e-82 K Acetyltransferase (GNAT) domain
KHDCFEJC_03009 2.6e-158 yvfR V ABC transporter
KHDCFEJC_03010 1.1e-133 yvfS V ABC-2 type transporter
KHDCFEJC_03011 5.2e-201 desK 2.7.13.3 T Histidine kinase
KHDCFEJC_03012 4e-102 desR K helix_turn_helix, Lux Regulon
KHDCFEJC_03013 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KHDCFEJC_03014 3.1e-13 S Alpha beta hydrolase
KHDCFEJC_03015 1.1e-170 C nadph quinone reductase
KHDCFEJC_03016 1.9e-161 K Transcriptional regulator
KHDCFEJC_03017 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
KHDCFEJC_03018 9.9e-112 GM NmrA-like family
KHDCFEJC_03019 7.7e-160 S Alpha beta hydrolase
KHDCFEJC_03020 1.3e-128 K Helix-turn-helix domain, rpiR family
KHDCFEJC_03021 1.6e-79 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
KHDCFEJC_03022 5e-122 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
KHDCFEJC_03023 0.0 CP_1020 S Zinc finger, swim domain protein
KHDCFEJC_03024 7.5e-112 GM epimerase
KHDCFEJC_03025 1.4e-68 S Protein of unknown function (DUF1722)
KHDCFEJC_03026 9.1e-71 yneH 1.20.4.1 P ArsC family
KHDCFEJC_03027 6.3e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
KHDCFEJC_03028 1e-136 K DeoR C terminal sensor domain
KHDCFEJC_03029 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KHDCFEJC_03030 2.8e-210 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KHDCFEJC_03031 4.3e-77 K Transcriptional regulator
KHDCFEJC_03032 8.5e-241 EGP Major facilitator Superfamily
KHDCFEJC_03033 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHDCFEJC_03034 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
KHDCFEJC_03035 3.4e-180 C Zinc-binding dehydrogenase
KHDCFEJC_03036 3.4e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
KHDCFEJC_03037 6.6e-207
KHDCFEJC_03038 2.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
KHDCFEJC_03039 7.8e-61 P Rhodanese Homology Domain
KHDCFEJC_03040 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KHDCFEJC_03041 6.9e-84 K helix_turn_helix multiple antibiotic resistance protein
KHDCFEJC_03042 2.3e-165 drrA V ABC transporter
KHDCFEJC_03043 9.1e-120 drrB U ABC-2 type transporter
KHDCFEJC_03044 8.4e-221 M O-Antigen ligase
KHDCFEJC_03045 5.1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
KHDCFEJC_03046 2.7e-196 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHDCFEJC_03047 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KHDCFEJC_03048 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHDCFEJC_03049 7.3e-29 S Protein of unknown function (DUF2929)
KHDCFEJC_03050 0.0 dnaE 2.7.7.7 L DNA polymerase
KHDCFEJC_03051 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KHDCFEJC_03052 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KHDCFEJC_03053 1.5e-74 yeaL S Protein of unknown function (DUF441)
KHDCFEJC_03054 2.9e-170 cvfB S S1 domain
KHDCFEJC_03055 1.1e-164 xerD D recombinase XerD
KHDCFEJC_03056 6.2e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHDCFEJC_03057 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHDCFEJC_03058 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHDCFEJC_03059 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KHDCFEJC_03060 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHDCFEJC_03061 3.8e-193 ypbB 5.1.3.1 S Helix-turn-helix domain
KHDCFEJC_03062 2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
KHDCFEJC_03063 4.4e-19 M Lysin motif
KHDCFEJC_03064 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KHDCFEJC_03065 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
KHDCFEJC_03066 1.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KHDCFEJC_03067 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHDCFEJC_03068 5.4e-218 S Tetratricopeptide repeat protein
KHDCFEJC_03069 2e-149 3.1.3.102, 3.1.3.104 S hydrolase
KHDCFEJC_03070 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KHDCFEJC_03071 4.7e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KHDCFEJC_03072 9.6e-85
KHDCFEJC_03073 0.0 yfmR S ABC transporter, ATP-binding protein
KHDCFEJC_03074 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHDCFEJC_03075 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHDCFEJC_03076 5.1e-148 DegV S EDD domain protein, DegV family
KHDCFEJC_03077 1.4e-146 ypmR E GDSL-like Lipase/Acylhydrolase
KHDCFEJC_03078 7.7e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KHDCFEJC_03079 3.4e-35 yozE S Belongs to the UPF0346 family
KHDCFEJC_03080 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KHDCFEJC_03081 9.5e-251 emrY EGP Major facilitator Superfamily
KHDCFEJC_03082 7.9e-199 XK27_00915 C Luciferase-like monooxygenase
KHDCFEJC_03083 1.9e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
KHDCFEJC_03084 8.9e-170 cpsY K Transcriptional regulator, LysR family
KHDCFEJC_03085 5.2e-228 XK27_05470 E Methionine synthase
KHDCFEJC_03086 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHDCFEJC_03087 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHDCFEJC_03088 3.3e-158 dprA LU DNA protecting protein DprA
KHDCFEJC_03089 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHDCFEJC_03090 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHDCFEJC_03091 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KHDCFEJC_03092 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KHDCFEJC_03093 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KHDCFEJC_03094 1.4e-169 lacX 5.1.3.3 G Aldose 1-epimerase
KHDCFEJC_03095 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHDCFEJC_03096 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHDCFEJC_03097 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHDCFEJC_03098 1.2e-177 K Transcriptional regulator
KHDCFEJC_03099 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
KHDCFEJC_03100 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KHDCFEJC_03101 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHDCFEJC_03102 4.2e-32 S YozE SAM-like fold
KHDCFEJC_03103 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)