ORF_ID e_value Gene_name EC_number CAZy COGs Description
EBFKHPNK_00001 1.1e-26 Q TIGRFAM amino acid adenylation domain
EBFKHPNK_00002 0.0 srfAC Q TIGRFAM amino acid adenylation domain
EBFKHPNK_00009 9e-78 tspO T membrane
EBFKHPNK_00010 1.7e-131 dksA T COG1734 DnaK suppressor protein
EBFKHPNK_00011 3.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
EBFKHPNK_00012 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EBFKHPNK_00013 3.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EBFKHPNK_00014 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EBFKHPNK_00015 2e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EBFKHPNK_00016 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EBFKHPNK_00017 2.3e-24 S Domain of Unknown Function (DUF1540)
EBFKHPNK_00018 1.9e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EBFKHPNK_00019 2.6e-239 cydA 1.10.3.14 C oxidase, subunit
EBFKHPNK_00020 3e-40 rpmE2 J Ribosomal protein L31
EBFKHPNK_00021 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EBFKHPNK_00022 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EBFKHPNK_00023 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EBFKHPNK_00024 6.1e-76 ytkA S YtkA-like
EBFKHPNK_00026 1.6e-76 dps P Belongs to the Dps family
EBFKHPNK_00027 1.7e-61 ytkC S Bacteriophage holin family
EBFKHPNK_00028 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
EBFKHPNK_00029 1.4e-126 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EBFKHPNK_00030 3.2e-144 ytlC P ABC transporter
EBFKHPNK_00031 1.6e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EBFKHPNK_00032 6.7e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EBFKHPNK_00033 1.6e-38 ytmB S Protein of unknown function (DUF2584)
EBFKHPNK_00034 3.1e-308 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EBFKHPNK_00035 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBFKHPNK_00036 0.0 asnB 6.3.5.4 E Asparagine synthase
EBFKHPNK_00037 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
EBFKHPNK_00038 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EBFKHPNK_00039 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
EBFKHPNK_00040 2.4e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
EBFKHPNK_00041 4e-142 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
EBFKHPNK_00043 3.9e-107 ytqB J Putative rRNA methylase
EBFKHPNK_00044 2.1e-190 yhcC S Fe-S oxidoreductase
EBFKHPNK_00045 3.9e-285 norB EGP COG0477 Permeases of the major facilitator superfamily
EBFKHPNK_00046 4.7e-194 K helix_turn_helix, Arsenical Resistance Operon Repressor
EBFKHPNK_00047 7.4e-40 ytzC S Protein of unknown function (DUF2524)
EBFKHPNK_00049 3.9e-66 ytrA K GntR family transcriptional regulator
EBFKHPNK_00050 4.2e-161 ytrB P abc transporter atp-binding protein
EBFKHPNK_00051 5e-163 S ABC-2 family transporter protein
EBFKHPNK_00052 2.9e-171 P ABC-2 family transporter protein
EBFKHPNK_00053 3.1e-149
EBFKHPNK_00054 1.3e-125 ytrE V ABC transporter, ATP-binding protein
EBFKHPNK_00055 3.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
EBFKHPNK_00056 9.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_00057 1.1e-165 T PhoQ Sensor
EBFKHPNK_00058 9.8e-135 bceA V ABC transporter, ATP-binding protein
EBFKHPNK_00059 0.0 bceB V ABC transporter (permease)
EBFKHPNK_00060 2.8e-123 ywaF S Integral membrane protein
EBFKHPNK_00061 6.1e-208 yttB EGP Major facilitator Superfamily
EBFKHPNK_00062 8e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EBFKHPNK_00063 1.2e-52 ytvB S Protein of unknown function (DUF4257)
EBFKHPNK_00064 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EBFKHPNK_00065 5.6e-52 ytwF P Sulfurtransferase
EBFKHPNK_00066 5.4e-86 M Acetyltransferase (GNAT) domain
EBFKHPNK_00067 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
EBFKHPNK_00068 1.8e-142 amyC P ABC transporter (permease)
EBFKHPNK_00069 9e-167 amyD G Binding-protein-dependent transport system inner membrane component
EBFKHPNK_00070 2.7e-246 msmE G Bacterial extracellular solute-binding protein
EBFKHPNK_00071 7.5e-186 msmR K Transcriptional regulator
EBFKHPNK_00072 9e-26 yteV S Sporulation protein Cse60
EBFKHPNK_00073 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
EBFKHPNK_00074 3.3e-236 ytfP S HI0933-like protein
EBFKHPNK_00075 5e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EBFKHPNK_00076 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EBFKHPNK_00077 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
EBFKHPNK_00078 1.7e-128 ythP V ABC transporter
EBFKHPNK_00079 9.3e-217 ythQ U Bacterial ABC transporter protein EcsB
EBFKHPNK_00080 5.3e-229 pbuO S permease
EBFKHPNK_00081 1.6e-268 pepV 3.5.1.18 E Dipeptidase
EBFKHPNK_00082 2.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EBFKHPNK_00083 6.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EBFKHPNK_00084 9.9e-169 ytlQ
EBFKHPNK_00085 8e-179 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EBFKHPNK_00086 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
EBFKHPNK_00087 3.5e-45 ytzH S YtzH-like protein
EBFKHPNK_00088 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EBFKHPNK_00089 2.7e-165 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
EBFKHPNK_00090 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
EBFKHPNK_00091 1.7e-51 ytzB S small secreted protein
EBFKHPNK_00092 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EBFKHPNK_00093 4.5e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
EBFKHPNK_00094 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EBFKHPNK_00095 3.7e-148 ytpQ S Belongs to the UPF0354 family
EBFKHPNK_00096 7e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EBFKHPNK_00097 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
EBFKHPNK_00098 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EBFKHPNK_00099 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EBFKHPNK_00100 1.7e-16 ytxH S COG4980 Gas vesicle protein
EBFKHPNK_00101 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
EBFKHPNK_00102 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EBFKHPNK_00103 4.2e-181 ccpA K catabolite control protein A
EBFKHPNK_00104 5.1e-145 motA N flagellar motor
EBFKHPNK_00105 1.1e-119 motS N Flagellar motor protein
EBFKHPNK_00106 6.6e-231 acuC BQ histone deacetylase
EBFKHPNK_00107 7.1e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
EBFKHPNK_00108 8.9e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EBFKHPNK_00109 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EBFKHPNK_00110 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EBFKHPNK_00111 2.8e-46 azlD S Branched-chain amino acid transport protein (AzlD)
EBFKHPNK_00112 2.6e-124 azlC E AzlC protein
EBFKHPNK_00113 7.5e-149 K Transcriptional regulator
EBFKHPNK_00114 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EBFKHPNK_00115 1.6e-140 E GDSL-like Lipase/Acylhydrolase family
EBFKHPNK_00117 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
EBFKHPNK_00118 7.3e-09
EBFKHPNK_00119 3.7e-221 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EBFKHPNK_00120 1.4e-101 yokH G SMI1 / KNR4 family
EBFKHPNK_00121 4.8e-257 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EBFKHPNK_00122 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBFKHPNK_00123 4.3e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
EBFKHPNK_00124 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
EBFKHPNK_00125 1.7e-108 yttP K Transcriptional regulator
EBFKHPNK_00126 2.3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EBFKHPNK_00127 4.3e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EBFKHPNK_00128 4e-240 braB E Component of the transport system for branched-chain amino acids
EBFKHPNK_00129 4.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
EBFKHPNK_00130 1.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBFKHPNK_00131 3.9e-31 sspB S spore protein
EBFKHPNK_00132 2.1e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EBFKHPNK_00133 0.0 ytcJ S amidohydrolase
EBFKHPNK_00134 3.3e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBFKHPNK_00135 6.4e-182 sppA OU signal peptide peptidase SppA
EBFKHPNK_00136 4.5e-88 yteJ S RDD family
EBFKHPNK_00137 6.5e-109 ytfI S Protein of unknown function (DUF2953)
EBFKHPNK_00138 1.6e-60 ytfJ S Sporulation protein YtfJ
EBFKHPNK_00139 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EBFKHPNK_00140 1.4e-184 ytxK 2.1.1.72 L DNA methylase
EBFKHPNK_00141 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EBFKHPNK_00142 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
EBFKHPNK_00143 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EBFKHPNK_00144 3.2e-264 argH 4.3.2.1 E argininosuccinate lyase
EBFKHPNK_00146 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_00147 9.6e-129 ytkL S Belongs to the UPF0173 family
EBFKHPNK_00148 7.5e-239 ytoI K transcriptional regulator containing CBS domains
EBFKHPNK_00149 3.1e-47 ytpI S YtpI-like protein
EBFKHPNK_00150 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
EBFKHPNK_00151 5.8e-23
EBFKHPNK_00152 1.1e-86 ytrI
EBFKHPNK_00153 3.2e-56 ytrH S Sporulation protein YtrH
EBFKHPNK_00154 0.0 dnaE 2.7.7.7 L DNA polymerase
EBFKHPNK_00155 3.7e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
EBFKHPNK_00156 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EBFKHPNK_00157 1.5e-180 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EBFKHPNK_00158 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EBFKHPNK_00159 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EBFKHPNK_00160 4.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
EBFKHPNK_00161 1.2e-192 ytvI S sporulation integral membrane protein YtvI
EBFKHPNK_00162 2.5e-72 yeaL S membrane
EBFKHPNK_00163 8.5e-48 yjdF S Protein of unknown function (DUF2992)
EBFKHPNK_00164 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
EBFKHPNK_00165 3.1e-242 icd 1.1.1.42 C isocitrate
EBFKHPNK_00166 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
EBFKHPNK_00167 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_00168 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
EBFKHPNK_00169 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBFKHPNK_00170 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EBFKHPNK_00171 3.6e-106 ytaF P Probably functions as a manganese efflux pump
EBFKHPNK_00172 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EBFKHPNK_00173 3.4e-160 ytbE S reductase
EBFKHPNK_00174 2.2e-205 ytbD EGP Major facilitator Superfamily
EBFKHPNK_00175 2e-67 ytcD K Transcriptional regulator
EBFKHPNK_00176 1.5e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EBFKHPNK_00177 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EBFKHPNK_00178 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBFKHPNK_00179 2.9e-257 dnaB L Membrane attachment protein
EBFKHPNK_00180 4.3e-172 dnaI L Primosomal protein DnaI
EBFKHPNK_00181 7.9e-109 ytxB S SNARE associated Golgi protein
EBFKHPNK_00182 8e-154 ytxC S YtxC-like family
EBFKHPNK_00183 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EBFKHPNK_00184 7.1e-152 ysaA S HAD-hyrolase-like
EBFKHPNK_00185 0.0 lytS 2.7.13.3 T Histidine kinase
EBFKHPNK_00186 8.4e-131 lytT T COG3279 Response regulator of the LytR AlgR family
EBFKHPNK_00187 3.1e-40 lrgA S effector of murein hydrolase LrgA
EBFKHPNK_00188 8.4e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EBFKHPNK_00189 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBFKHPNK_00190 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EBFKHPNK_00191 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EBFKHPNK_00192 3.5e-42 ysdA S Membrane
EBFKHPNK_00193 9.2e-68 ysdB S Sigma-w pathway protein YsdB
EBFKHPNK_00194 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
EBFKHPNK_00195 3.4e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EBFKHPNK_00196 8.9e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EBFKHPNK_00197 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
EBFKHPNK_00198 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EBFKHPNK_00199 1.2e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EBFKHPNK_00200 1.4e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EBFKHPNK_00201 1.8e-253 araN G carbohydrate transport
EBFKHPNK_00202 8.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
EBFKHPNK_00203 4.4e-144 araQ G transport system permease
EBFKHPNK_00204 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
EBFKHPNK_00205 0.0 cstA T Carbon starvation protein
EBFKHPNK_00206 8e-257 glcF C Glycolate oxidase
EBFKHPNK_00207 2e-258 glcD 1.1.3.15 C FAD binding domain
EBFKHPNK_00208 3.8e-204 ysfB KT regulator
EBFKHPNK_00209 2e-32 sspI S Belongs to the SspI family
EBFKHPNK_00210 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBFKHPNK_00211 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBFKHPNK_00212 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EBFKHPNK_00213 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EBFKHPNK_00214 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EBFKHPNK_00215 2.3e-82 cvpA S membrane protein, required for colicin V production
EBFKHPNK_00216 0.0 polX L COG1796 DNA polymerase IV (family X)
EBFKHPNK_00217 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EBFKHPNK_00218 4.7e-67 yshE S membrane
EBFKHPNK_00219 1.9e-121 ywbB S Protein of unknown function (DUF2711)
EBFKHPNK_00220 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EBFKHPNK_00221 9.2e-104 fadR K Transcriptional regulator
EBFKHPNK_00222 4.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EBFKHPNK_00223 2e-138 etfB C Electron transfer flavoprotein
EBFKHPNK_00224 1.1e-178 etfA C Electron transfer flavoprotein
EBFKHPNK_00225 1.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
EBFKHPNK_00226 2.5e-52 trxA O Belongs to the thioredoxin family
EBFKHPNK_00227 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EBFKHPNK_00228 4.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EBFKHPNK_00229 1.2e-79 yslB S Protein of unknown function (DUF2507)
EBFKHPNK_00230 4.8e-108 sdhC C succinate dehydrogenase
EBFKHPNK_00231 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EBFKHPNK_00232 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EBFKHPNK_00233 9.3e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
EBFKHPNK_00234 2e-30 gerE K Transcriptional regulator
EBFKHPNK_00235 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
EBFKHPNK_00236 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EBFKHPNK_00237 3.1e-198 gerM S COG5401 Spore germination protein
EBFKHPNK_00238 1.5e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBFKHPNK_00239 2.5e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EBFKHPNK_00240 5.3e-92 ysnB S Phosphoesterase
EBFKHPNK_00244 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
EBFKHPNK_00245 1.3e-244 hsdM 2.1.1.72 L type I restriction-modification system
EBFKHPNK_00246 1.6e-82 hsdS 3.1.21.3 L COG0732 Restriction endonuclease S subunits
EBFKHPNK_00247 2.5e-11 pinR3 L Resolvase, N terminal domain
EBFKHPNK_00248 1.8e-37 pinR3 L Resolvase, N terminal domain
EBFKHPNK_00251 0.0 ilvB 2.2.1.6 E Acetolactate synthase
EBFKHPNK_00252 1.6e-83 ilvN 2.2.1.6 E Acetolactate synthase
EBFKHPNK_00253 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBFKHPNK_00254 1.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EBFKHPNK_00255 5.3e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EBFKHPNK_00256 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBFKHPNK_00257 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBFKHPNK_00258 1.2e-188 ysoA H Tetratricopeptide repeat
EBFKHPNK_00259 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EBFKHPNK_00260 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EBFKHPNK_00261 1.8e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
EBFKHPNK_00262 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EBFKHPNK_00263 3.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
EBFKHPNK_00264 3.8e-87 ysxD
EBFKHPNK_00265 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBFKHPNK_00266 8e-146 hemX O cytochrome C
EBFKHPNK_00267 2.4e-175 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EBFKHPNK_00268 5e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EBFKHPNK_00269 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
EBFKHPNK_00270 1.2e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EBFKHPNK_00271 4.6e-218 spoVID M stage VI sporulation protein D
EBFKHPNK_00272 4.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EBFKHPNK_00273 2.8e-25
EBFKHPNK_00274 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EBFKHPNK_00275 4.3e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EBFKHPNK_00276 7.8e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EBFKHPNK_00277 3.4e-135 spoIIB S Sporulation related domain
EBFKHPNK_00278 2e-100 maf D septum formation protein Maf
EBFKHPNK_00279 1.8e-127 radC E Belongs to the UPF0758 family
EBFKHPNK_00280 4e-184 mreB D Rod shape-determining protein MreB
EBFKHPNK_00281 1.2e-157 mreC M Involved in formation and maintenance of cell shape
EBFKHPNK_00282 5.4e-84 mreD M shape-determining protein
EBFKHPNK_00283 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EBFKHPNK_00284 2.3e-142 minD D Belongs to the ParA family
EBFKHPNK_00285 1.9e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
EBFKHPNK_00286 2.7e-160 spoIVFB S Stage IV sporulation protein
EBFKHPNK_00287 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
EBFKHPNK_00288 3.2e-56 ysxB J ribosomal protein
EBFKHPNK_00289 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EBFKHPNK_00290 3.3e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
EBFKHPNK_00291 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBFKHPNK_00292 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
EBFKHPNK_00293 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
EBFKHPNK_00294 5.5e-95 niaR S small molecule binding protein (contains 3H domain)
EBFKHPNK_00295 4e-220 nifS 2.8.1.7 E Cysteine desulfurase
EBFKHPNK_00296 1.5e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
EBFKHPNK_00297 6.9e-153 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
EBFKHPNK_00298 2.7e-210 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EBFKHPNK_00299 5.7e-145 safA M spore coat assembly protein SafA
EBFKHPNK_00300 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EBFKHPNK_00302 3.7e-93 bofC S BofC C-terminal domain
EBFKHPNK_00303 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EBFKHPNK_00304 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EBFKHPNK_00305 1.6e-20 yrzS S Protein of unknown function (DUF2905)
EBFKHPNK_00306 2.4e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EBFKHPNK_00307 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EBFKHPNK_00308 2.5e-37 yajC U Preprotein translocase subunit YajC
EBFKHPNK_00309 2.4e-60 yrzE S Protein of unknown function (DUF3792)
EBFKHPNK_00310 6.2e-109 yrbG S membrane
EBFKHPNK_00311 1.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EBFKHPNK_00312 1.3e-50 yrzD S Post-transcriptional regulator
EBFKHPNK_00313 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBFKHPNK_00314 9.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
EBFKHPNK_00315 2.4e-45 yrvD S Lipopolysaccharide assembly protein A domain
EBFKHPNK_00316 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
EBFKHPNK_00317 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EBFKHPNK_00318 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBFKHPNK_00319 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EBFKHPNK_00320 2.8e-277 lytH 3.5.1.28 M COG3103 SH3 domain protein
EBFKHPNK_00323 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
EBFKHPNK_00324 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBFKHPNK_00325 7.4e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EBFKHPNK_00326 5.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EBFKHPNK_00327 7.8e-64 cymR K Transcriptional regulator
EBFKHPNK_00328 5.2e-212 iscS 2.8.1.7 E Cysteine desulfurase
EBFKHPNK_00329 2.7e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EBFKHPNK_00330 1.7e-18 S COG0457 FOG TPR repeat
EBFKHPNK_00331 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EBFKHPNK_00332 1.5e-82 yrrD S protein conserved in bacteria
EBFKHPNK_00333 2.9e-30 yrzR
EBFKHPNK_00334 2.1e-08 S Protein of unknown function (DUF3918)
EBFKHPNK_00335 4.4e-107 glnP P ABC transporter
EBFKHPNK_00336 1.2e-109 gluC P ABC transporter
EBFKHPNK_00337 3.6e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
EBFKHPNK_00338 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EBFKHPNK_00339 5.4e-163 yrrI S AI-2E family transporter
EBFKHPNK_00340 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBFKHPNK_00341 8.5e-41 yrzL S Belongs to the UPF0297 family
EBFKHPNK_00342 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBFKHPNK_00343 7.1e-46 yrzB S Belongs to the UPF0473 family
EBFKHPNK_00344 1.7e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBFKHPNK_00345 2.3e-116 yrrM 2.1.1.104 S O-methyltransferase
EBFKHPNK_00346 1.7e-173 yegQ O Peptidase U32
EBFKHPNK_00347 7.9e-246 yegQ O COG0826 Collagenase and related proteases
EBFKHPNK_00348 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
EBFKHPNK_00349 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EBFKHPNK_00350 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
EBFKHPNK_00351 8.1e-70 yrrS S Protein of unknown function (DUF1510)
EBFKHPNK_00352 4.1e-27 yrzA S Protein of unknown function (DUF2536)
EBFKHPNK_00353 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
EBFKHPNK_00354 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EBFKHPNK_00355 4.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
EBFKHPNK_00356 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EBFKHPNK_00357 1.8e-34 yrhC S YrhC-like protein
EBFKHPNK_00358 7e-81 yrhD S Protein of unknown function (DUF1641)
EBFKHPNK_00359 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EBFKHPNK_00360 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
EBFKHPNK_00361 8e-143 focA P Formate nitrite
EBFKHPNK_00363 3.9e-93 yrhH Q methyltransferase
EBFKHPNK_00364 2.7e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
EBFKHPNK_00365 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EBFKHPNK_00366 8.4e-213 ynfM EGP Major facilitator Superfamily
EBFKHPNK_00367 5.3e-164 yybE K Transcriptional regulator
EBFKHPNK_00368 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBFKHPNK_00369 8.2e-184 romA S Beta-lactamase superfamily domain
EBFKHPNK_00370 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
EBFKHPNK_00371 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
EBFKHPNK_00372 6.9e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
EBFKHPNK_00373 4.5e-129 glvR K Helix-turn-helix domain, rpiR family
EBFKHPNK_00374 2.7e-146 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
EBFKHPNK_00375 4.7e-143 S hydrolase
EBFKHPNK_00376 1.1e-92 yrdA S DinB family
EBFKHPNK_00377 5.7e-81 yyaR K Acetyltransferase (GNAT) domain
EBFKHPNK_00378 9e-219 tetL EGP Major facilitator Superfamily
EBFKHPNK_00379 1.3e-31 yyaR K acetyltransferase
EBFKHPNK_00380 4.7e-99 adk 2.7.4.3 F adenylate kinase activity
EBFKHPNK_00381 2.8e-100 yrkN K Acetyltransferase (GNAT) family
EBFKHPNK_00382 1.3e-216 yrkO P Protein of unknown function (DUF418)
EBFKHPNK_00383 1.6e-123 T Transcriptional regulator
EBFKHPNK_00384 5.6e-239 yrkQ T Histidine kinase
EBFKHPNK_00385 3e-69 psiE S Belongs to the PsiE family
EBFKHPNK_00386 8.5e-93 K Transcriptional regulator PadR-like family
EBFKHPNK_00387 8.9e-161 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
EBFKHPNK_00388 1.5e-15 xkdG S Phage capsid family
EBFKHPNK_00389 2.9e-70 K MerR family transcriptional regulator
EBFKHPNK_00390 2e-136 yvgN 1.1.1.346 S Reductase
EBFKHPNK_00392 4.7e-20 xkdR S Protein of unknown function (DUF2577)
EBFKHPNK_00393 2.3e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EBFKHPNK_00394 2.9e-25 xkdS S Protein of unknown function (DUF2634)
EBFKHPNK_00395 5.2e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBFKHPNK_00396 1.7e-211 EGP Major facilitator Superfamily
EBFKHPNK_00397 7.2e-107 yqeD S SNARE associated Golgi protein
EBFKHPNK_00398 3.4e-140 3.5.1.104 G Polysaccharide deacetylase
EBFKHPNK_00399 7.7e-140 yqeF E GDSL-like Lipase/Acylhydrolase
EBFKHPNK_00401 2e-94 yqeG S hydrolase of the HAD superfamily
EBFKHPNK_00402 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EBFKHPNK_00403 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EBFKHPNK_00404 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
EBFKHPNK_00405 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBFKHPNK_00406 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EBFKHPNK_00407 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EBFKHPNK_00408 2.2e-139 yqeM Q Methyltransferase
EBFKHPNK_00409 1.6e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EBFKHPNK_00410 1.5e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EBFKHPNK_00411 8e-105 comEB 3.5.4.12 F ComE operon protein 2
EBFKHPNK_00412 0.0 comEC S Competence protein ComEC
EBFKHPNK_00413 2.1e-180 holA 2.7.7.7 L DNA polymerase III delta subunit
EBFKHPNK_00414 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
EBFKHPNK_00415 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EBFKHPNK_00416 3.2e-220 spoIIP M stage II sporulation protein P
EBFKHPNK_00417 3.8e-54 yqxA S Protein of unknown function (DUF3679)
EBFKHPNK_00418 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EBFKHPNK_00419 3.7e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
EBFKHPNK_00420 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EBFKHPNK_00421 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBFKHPNK_00422 0.0 dnaK O Heat shock 70 kDa protein
EBFKHPNK_00423 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EBFKHPNK_00424 4.6e-174 prmA J Methylates ribosomal protein L11
EBFKHPNK_00425 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EBFKHPNK_00426 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
EBFKHPNK_00427 3e-157 yqeW P COG1283 Na phosphate symporter
EBFKHPNK_00428 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EBFKHPNK_00429 1.2e-68 yqeY S Yqey-like protein
EBFKHPNK_00430 1.7e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
EBFKHPNK_00431 1.6e-121 yqfA S UPF0365 protein
EBFKHPNK_00432 1.7e-54 yqfB
EBFKHPNK_00433 9.3e-46 yqfC S sporulation protein YqfC
EBFKHPNK_00434 6.8e-215 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
EBFKHPNK_00435 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
EBFKHPNK_00436 0.0 yqfF S membrane-associated HD superfamily hydrolase
EBFKHPNK_00437 2.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EBFKHPNK_00438 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EBFKHPNK_00439 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EBFKHPNK_00440 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EBFKHPNK_00441 1.8e-16 S YqzL-like protein
EBFKHPNK_00442 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
EBFKHPNK_00443 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EBFKHPNK_00444 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EBFKHPNK_00445 4.5e-112 ccpN K CBS domain
EBFKHPNK_00446 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EBFKHPNK_00447 6.1e-88 yaiI S Belongs to the UPF0178 family
EBFKHPNK_00448 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EBFKHPNK_00449 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EBFKHPNK_00450 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
EBFKHPNK_00451 2.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
EBFKHPNK_00452 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EBFKHPNK_00453 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBFKHPNK_00454 5.3e-50 yqfQ S YqfQ-like protein
EBFKHPNK_00455 4e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EBFKHPNK_00456 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EBFKHPNK_00457 9.3e-37 yqfT S Protein of unknown function (DUF2624)
EBFKHPNK_00458 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EBFKHPNK_00459 8.4e-72 zur P Belongs to the Fur family
EBFKHPNK_00460 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
EBFKHPNK_00461 2.3e-52 yqfX S membrane
EBFKHPNK_00462 9e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EBFKHPNK_00463 1.2e-46 yqfZ M LysM domain
EBFKHPNK_00464 8.7e-131 yqgB S Protein of unknown function (DUF1189)
EBFKHPNK_00465 6e-77 yqgC S protein conserved in bacteria
EBFKHPNK_00466 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
EBFKHPNK_00467 2e-228 yqgE EGP Major facilitator superfamily
EBFKHPNK_00468 0.0 pbpA 3.4.16.4 M penicillin-binding protein
EBFKHPNK_00469 8.4e-157 pstS P Phosphate
EBFKHPNK_00470 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
EBFKHPNK_00471 1.8e-156 pstA P Phosphate transport system permease
EBFKHPNK_00472 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EBFKHPNK_00473 1.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EBFKHPNK_00474 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EBFKHPNK_00475 1.2e-50 yqzD
EBFKHPNK_00476 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EBFKHPNK_00477 2.3e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EBFKHPNK_00478 4e-07 yqgO
EBFKHPNK_00479 3.3e-212 nhaC C Na H antiporter
EBFKHPNK_00480 1e-28 yqgQ S Protein conserved in bacteria
EBFKHPNK_00481 2.2e-179 glcK 2.7.1.2 G Glucokinase
EBFKHPNK_00482 9.9e-224 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
EBFKHPNK_00483 3.5e-199 yqgU
EBFKHPNK_00484 6.9e-50 yqgV S Thiamine-binding protein
EBFKHPNK_00485 5.4e-20 yqgW S Protein of unknown function (DUF2759)
EBFKHPNK_00486 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EBFKHPNK_00487 3.1e-37 yqgY S Protein of unknown function (DUF2626)
EBFKHPNK_00488 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
EBFKHPNK_00490 3.8e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EBFKHPNK_00491 3.3e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EBFKHPNK_00492 9e-186 corA P Mg2 transporter protein
EBFKHPNK_00493 8.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EBFKHPNK_00494 3e-182 comGB NU COG1459 Type II secretory pathway, component PulF
EBFKHPNK_00495 2.2e-48 comGC U Required for transformation and DNA binding
EBFKHPNK_00496 1.6e-73 gspH NU Tfp pilus assembly protein FimT
EBFKHPNK_00497 5.8e-20 comGE
EBFKHPNK_00498 3.3e-65 comGF U Putative Competence protein ComGF
EBFKHPNK_00499 2.9e-63 S ComG operon protein 7
EBFKHPNK_00500 2.3e-26 yqzE S YqzE-like protein
EBFKHPNK_00501 1.1e-53 yqzG S Protein of unknown function (DUF3889)
EBFKHPNK_00502 7.2e-121 yqxM
EBFKHPNK_00503 1e-70 sipW 3.4.21.89 U Signal peptidase
EBFKHPNK_00504 3.3e-141 tasA S Cell division protein FtsN
EBFKHPNK_00505 7.8e-55 sinR K transcriptional
EBFKHPNK_00506 5.2e-23 sinI S Anti-repressor SinI
EBFKHPNK_00507 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
EBFKHPNK_00508 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EBFKHPNK_00509 9.7e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
EBFKHPNK_00510 6e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EBFKHPNK_00511 1.8e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EBFKHPNK_00512 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
EBFKHPNK_00513 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EBFKHPNK_00514 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EBFKHPNK_00515 1.4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
EBFKHPNK_00516 3.4e-62 yqhP
EBFKHPNK_00517 2e-172 yqhQ S Protein of unknown function (DUF1385)
EBFKHPNK_00518 3.7e-88 yqhR S Conserved membrane protein YqhR
EBFKHPNK_00519 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EBFKHPNK_00520 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBFKHPNK_00521 1.8e-36 yqhV S Protein of unknown function (DUF2619)
EBFKHPNK_00522 2.3e-170 spoIIIAA S stage III sporulation protein AA
EBFKHPNK_00523 8.3e-85 spoIIIAB S Stage III sporulation protein
EBFKHPNK_00524 7.6e-29 spoIIIAC S stage III sporulation protein AC
EBFKHPNK_00525 2.5e-41 spoIIIAD S Stage III sporulation protein AD
EBFKHPNK_00526 6.3e-200 spoIIIAE S stage III sporulation protein AE
EBFKHPNK_00527 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
EBFKHPNK_00528 1.1e-116 spoIIIAG S stage III sporulation protein AG
EBFKHPNK_00529 2.5e-62 spoIIIAH S SpoIIIAH-like protein
EBFKHPNK_00530 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EBFKHPNK_00531 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EBFKHPNK_00532 8.1e-67 yqhY S protein conserved in bacteria
EBFKHPNK_00533 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBFKHPNK_00534 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBFKHPNK_00535 6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EBFKHPNK_00536 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EBFKHPNK_00537 3.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EBFKHPNK_00538 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBFKHPNK_00539 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
EBFKHPNK_00540 3.9e-78 argR K Regulates arginine biosynthesis genes
EBFKHPNK_00541 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
EBFKHPNK_00542 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
EBFKHPNK_00543 5.5e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EBFKHPNK_00544 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EBFKHPNK_00547 5.4e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EBFKHPNK_00549 1.8e-113 K Protein of unknown function (DUF1232)
EBFKHPNK_00550 2.2e-100 ytaF P Probably functions as a manganese efflux pump
EBFKHPNK_00551 5.5e-17
EBFKHPNK_00552 2.3e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
EBFKHPNK_00553 3.3e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EBFKHPNK_00554 9.1e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
EBFKHPNK_00555 8.2e-154 hbdA 1.1.1.157 I Dehydrogenase
EBFKHPNK_00556 4.7e-205 mmgC I acyl-CoA dehydrogenase
EBFKHPNK_00557 2.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
EBFKHPNK_00558 9.2e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
EBFKHPNK_00559 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EBFKHPNK_00560 2.7e-33 yqzF S Protein of unknown function (DUF2627)
EBFKHPNK_00561 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
EBFKHPNK_00562 4.3e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
EBFKHPNK_00563 9.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
EBFKHPNK_00564 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
EBFKHPNK_00565 1.8e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EBFKHPNK_00566 8.6e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EBFKHPNK_00567 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EBFKHPNK_00568 5.7e-204 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EBFKHPNK_00569 2.3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EBFKHPNK_00570 1.7e-75 yqiW S Belongs to the UPF0403 family
EBFKHPNK_00571 4.3e-119 L Molecular Function DNA binding, Biological Process DNA recombination
EBFKHPNK_00572 1.1e-40 L transposase activity
EBFKHPNK_00573 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
EBFKHPNK_00574 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
EBFKHPNK_00575 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EBFKHPNK_00576 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
EBFKHPNK_00577 3.1e-95 yqjB S protein conserved in bacteria
EBFKHPNK_00579 2.7e-73 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
EBFKHPNK_00580 2e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EBFKHPNK_00581 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
EBFKHPNK_00582 1.3e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EBFKHPNK_00583 2.4e-25 yqzJ
EBFKHPNK_00584 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EBFKHPNK_00585 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EBFKHPNK_00586 1.2e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBFKHPNK_00587 6.1e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EBFKHPNK_00588 3e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EBFKHPNK_00589 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EBFKHPNK_00590 6.4e-31 S GlpM protein
EBFKHPNK_00591 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
EBFKHPNK_00592 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EBFKHPNK_00595 1.2e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EBFKHPNK_00596 5.5e-130 IQ reductase
EBFKHPNK_00597 0.0 pksJ Q Polyketide synthase of type I
EBFKHPNK_00598 0.0 1.1.1.320 Q Polyketide synthase of type I
EBFKHPNK_00599 0.0 Q Polyketide synthase of type I
EBFKHPNK_00600 2e-158 pbuX F xanthine
EBFKHPNK_00602 6.5e-99 yrdC 3.5.1.19 Q Isochorismatase family
EBFKHPNK_00603 3e-34 ydfR S Protein of unknown function (DUF421)
EBFKHPNK_00604 1.6e-33 ydfR S Protein of unknown function (DUF421)
EBFKHPNK_00606 5.2e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
EBFKHPNK_00607 2e-106 J Acetyltransferase (GNAT) domain
EBFKHPNK_00608 2.5e-203 bcsA Q Naringenin-chalcone synthase
EBFKHPNK_00609 1.1e-89 ypbQ S protein conserved in bacteria
EBFKHPNK_00610 0.0 ypbR S Dynamin family
EBFKHPNK_00611 1e-38 ypbS S Protein of unknown function (DUF2533)
EBFKHPNK_00613 1.4e-164 polA 2.7.7.7 L 5'3' exonuclease
EBFKHPNK_00615 1.1e-68 rnhA 3.1.26.4 L Ribonuclease
EBFKHPNK_00616 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EBFKHPNK_00617 5.3e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
EBFKHPNK_00618 5.7e-28 ypeQ S Zinc-finger
EBFKHPNK_00619 1.2e-36 S Protein of unknown function (DUF2564)
EBFKHPNK_00620 3.3e-12 degR
EBFKHPNK_00621 1e-30 cspD K Cold-shock protein
EBFKHPNK_00622 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EBFKHPNK_00623 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBFKHPNK_00624 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EBFKHPNK_00625 5.4e-99 ypgQ S phosphohydrolase
EBFKHPNK_00626 2.8e-157 ypgR C COG0694 Thioredoxin-like proteins and domains
EBFKHPNK_00627 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EBFKHPNK_00628 3e-75 yphP S Belongs to the UPF0403 family
EBFKHPNK_00629 5.7e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
EBFKHPNK_00630 2.7e-114 ypjP S YpjP-like protein
EBFKHPNK_00631 1.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EBFKHPNK_00632 6.2e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EBFKHPNK_00633 2.5e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EBFKHPNK_00634 1.2e-109 hlyIII S protein, Hemolysin III
EBFKHPNK_00635 3.3e-178 pspF K Transcriptional regulator
EBFKHPNK_00636 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBFKHPNK_00637 2.6e-39 ypmP S Protein of unknown function (DUF2535)
EBFKHPNK_00638 1.3e-113 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EBFKHPNK_00639 4.4e-135 ypmR E GDSL-like Lipase/Acylhydrolase
EBFKHPNK_00640 1.2e-97 ypmS S protein conserved in bacteria
EBFKHPNK_00641 1.4e-66 ypoP K transcriptional
EBFKHPNK_00642 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBFKHPNK_00643 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EBFKHPNK_00644 1.4e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
EBFKHPNK_00645 4.3e-308 yokA L Recombinase
EBFKHPNK_00646 7.3e-84 G SMI1-KNR4 cell-wall
EBFKHPNK_00647 8.4e-78 yokF 3.1.31.1 L RNA catabolic process
EBFKHPNK_00648 4e-50 L Recombinase
EBFKHPNK_00649 3.7e-64 pbuX F xanthine
EBFKHPNK_00650 3.3e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EBFKHPNK_00651 3.5e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EBFKHPNK_00652 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
EBFKHPNK_00654 6.6e-22 S YpzG-like protein
EBFKHPNK_00655 8.4e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EBFKHPNK_00656 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EBFKHPNK_00657 1.8e-98 ypsA S Belongs to the UPF0398 family
EBFKHPNK_00658 9.9e-33 cotD S Inner spore coat protein D
EBFKHPNK_00659 2.5e-236 yprB L RNase_H superfamily
EBFKHPNK_00660 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EBFKHPNK_00661 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
EBFKHPNK_00662 6.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
EBFKHPNK_00663 2.1e-49 yppG S YppG-like protein
EBFKHPNK_00665 9.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
EBFKHPNK_00668 3.4e-188 yppC S Protein of unknown function (DUF2515)
EBFKHPNK_00669 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EBFKHPNK_00670 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EBFKHPNK_00671 1.8e-89 ypoC
EBFKHPNK_00672 7.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EBFKHPNK_00673 3e-130 dnaD L DNA replication protein DnaD
EBFKHPNK_00674 3.8e-251 asnS 6.1.1.22 J asparaginyl-tRNA
EBFKHPNK_00675 2.2e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EBFKHPNK_00676 4e-81 ypmB S protein conserved in bacteria
EBFKHPNK_00677 6.7e-23 ypmA S Protein of unknown function (DUF4264)
EBFKHPNK_00678 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EBFKHPNK_00679 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBFKHPNK_00680 5e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EBFKHPNK_00681 4.5e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EBFKHPNK_00682 5.3e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EBFKHPNK_00683 3.9e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EBFKHPNK_00684 1.8e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
EBFKHPNK_00685 5.6e-132 bshB1 S proteins, LmbE homologs
EBFKHPNK_00686 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
EBFKHPNK_00687 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EBFKHPNK_00688 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
EBFKHPNK_00689 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
EBFKHPNK_00690 2e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
EBFKHPNK_00691 5.1e-142 ypjB S sporulation protein
EBFKHPNK_00692 2.6e-106 ypjA S membrane
EBFKHPNK_00693 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
EBFKHPNK_00694 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
EBFKHPNK_00695 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
EBFKHPNK_00696 4.2e-77 ypiF S Protein of unknown function (DUF2487)
EBFKHPNK_00697 4.8e-99 ypiB S Belongs to the UPF0302 family
EBFKHPNK_00698 3.5e-233 S COG0457 FOG TPR repeat
EBFKHPNK_00699 8.2e-106 L Molecular Function DNA binding, Biological Process DNA recombination
EBFKHPNK_00700 9.3e-53 L COG2963 Transposase and inactivated derivatives
EBFKHPNK_00701 1.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EBFKHPNK_00702 2.7e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EBFKHPNK_00703 9.3e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBFKHPNK_00704 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EBFKHPNK_00705 2.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EBFKHPNK_00706 7.2e-118 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
EBFKHPNK_00707 3.9e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EBFKHPNK_00708 2e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBFKHPNK_00709 2.8e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBFKHPNK_00710 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EBFKHPNK_00711 8.4e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EBFKHPNK_00712 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBFKHPNK_00713 1.2e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
EBFKHPNK_00714 1.1e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EBFKHPNK_00715 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EBFKHPNK_00716 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EBFKHPNK_00717 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EBFKHPNK_00718 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EBFKHPNK_00719 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
EBFKHPNK_00720 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EBFKHPNK_00721 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EBFKHPNK_00722 2.4e-133 yphF
EBFKHPNK_00723 1.5e-16 yphE S Protein of unknown function (DUF2768)
EBFKHPNK_00724 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EBFKHPNK_00725 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EBFKHPNK_00726 5.5e-104 yphA
EBFKHPNK_00727 4.7e-08 S YpzI-like protein
EBFKHPNK_00728 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EBFKHPNK_00729 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
EBFKHPNK_00730 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EBFKHPNK_00731 1.4e-12 S Family of unknown function (DUF5359)
EBFKHPNK_00732 1.6e-61 ypfA M Flagellar protein YcgR
EBFKHPNK_00733 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
EBFKHPNK_00734 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
EBFKHPNK_00735 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
EBFKHPNK_00736 7.7e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
EBFKHPNK_00737 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EBFKHPNK_00738 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EBFKHPNK_00739 6.2e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
EBFKHPNK_00740 5.7e-85 ypbF S Protein of unknown function (DUF2663)
EBFKHPNK_00741 1e-78 ypbE M Lysin motif
EBFKHPNK_00742 9.9e-100 ypbD S metal-dependent membrane protease
EBFKHPNK_00743 9.4e-272 recQ 3.6.4.12 L DNA helicase
EBFKHPNK_00744 2.6e-197 ypbB 5.1.3.1 S protein conserved in bacteria
EBFKHPNK_00745 3.6e-41 fer C Ferredoxin
EBFKHPNK_00746 4.1e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EBFKHPNK_00747 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBFKHPNK_00748 3.2e-195 rsiX
EBFKHPNK_00749 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
EBFKHPNK_00750 0.0 resE 2.7.13.3 T Histidine kinase
EBFKHPNK_00751 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_00752 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EBFKHPNK_00753 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
EBFKHPNK_00754 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EBFKHPNK_00755 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EBFKHPNK_00756 2.9e-88 spmB S Spore maturation protein
EBFKHPNK_00757 2e-103 spmA S Spore maturation protein
EBFKHPNK_00758 1.8e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
EBFKHPNK_00759 2.9e-93 ypuI S Protein of unknown function (DUF3907)
EBFKHPNK_00760 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBFKHPNK_00761 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBFKHPNK_00763 8.4e-93 ypuF S Domain of unknown function (DUF309)
EBFKHPNK_00764 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EBFKHPNK_00765 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EBFKHPNK_00766 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EBFKHPNK_00767 1.4e-110 ribE 2.5.1.9 H Riboflavin synthase
EBFKHPNK_00768 1.4e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EBFKHPNK_00769 1.7e-49 ypuD
EBFKHPNK_00770 2.6e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EBFKHPNK_00771 1.4e-81 ccdC1 O Protein of unknown function (DUF1453)
EBFKHPNK_00772 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EBFKHPNK_00773 5.1e-154 ypuA S Secreted protein
EBFKHPNK_00774 1.5e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EBFKHPNK_00775 1.4e-270 spoVAF EG Stage V sporulation protein AF
EBFKHPNK_00776 1.8e-110 spoVAEA S stage V sporulation protein
EBFKHPNK_00777 3.8e-57 spoVAEB S stage V sporulation protein
EBFKHPNK_00778 5e-190 spoVAD I Stage V sporulation protein AD
EBFKHPNK_00779 2.1e-79 spoVAC S stage V sporulation protein AC
EBFKHPNK_00780 3.9e-60 spoVAB S Stage V sporulation protein AB
EBFKHPNK_00781 3.7e-111 spoVAA S Stage V sporulation protein AA
EBFKHPNK_00782 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBFKHPNK_00783 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EBFKHPNK_00784 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
EBFKHPNK_00785 3.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
EBFKHPNK_00786 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EBFKHPNK_00787 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EBFKHPNK_00788 3.7e-165 xerD L recombinase XerD
EBFKHPNK_00789 3.7e-37 S Protein of unknown function (DUF4227)
EBFKHPNK_00790 1.9e-80 fur P Belongs to the Fur family
EBFKHPNK_00791 2.1e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EBFKHPNK_00792 3.9e-34 yqkK
EBFKHPNK_00793 3.3e-22
EBFKHPNK_00794 1.7e-243 mleA 1.1.1.38 C malic enzyme
EBFKHPNK_00795 1.1e-243 mleN C Na H antiporter
EBFKHPNK_00796 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
EBFKHPNK_00797 8.5e-187 ansA 3.5.1.1 EJ L-asparaginase
EBFKHPNK_00798 3e-57 ansR K Transcriptional regulator
EBFKHPNK_00799 2.4e-220 yqxK 3.6.4.12 L DNA helicase
EBFKHPNK_00800 2.8e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
EBFKHPNK_00802 7e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
EBFKHPNK_00804 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
EBFKHPNK_00805 3.2e-39 yqkC S Protein of unknown function (DUF2552)
EBFKHPNK_00806 7.7e-61 yqkB S Belongs to the HesB IscA family
EBFKHPNK_00807 9.6e-175 yqkA K GrpB protein
EBFKHPNK_00808 7.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
EBFKHPNK_00809 3.9e-89 yqjY K acetyltransferase
EBFKHPNK_00810 9.4e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EBFKHPNK_00811 1.2e-58 S YolD-like protein
EBFKHPNK_00813 4.6e-186 yueF S transporter activity
EBFKHPNK_00815 1.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EBFKHPNK_00816 3.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
EBFKHPNK_00817 1.8e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
EBFKHPNK_00818 5.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_00819 2.9e-176 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
EBFKHPNK_00820 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EBFKHPNK_00821 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EBFKHPNK_00822 8.4e-240 pksG 2.3.3.10 I synthase
EBFKHPNK_00823 8e-221 eryK 1.14.13.154 C Cytochrome P450
EBFKHPNK_00824 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EBFKHPNK_00825 0.0 Q Polyketide synthase of type I
EBFKHPNK_00826 0.0 pfaA Q Polyketide synthase of type I
EBFKHPNK_00827 0.0 pksJ Q Polyketide synthase of type I
EBFKHPNK_00828 4e-99 S A nuclease of the HNH/ENDO VII superfamily with conserved WHH
EBFKHPNK_00829 9.6e-85 yokK S SMI1 / KNR4 family
EBFKHPNK_00830 2e-39 H Acetyltransferase (GNAT) domain
EBFKHPNK_00832 9.6e-195 S aspartate phosphatase
EBFKHPNK_00833 2.8e-76 yoqH M LysM domain
EBFKHPNK_00836 2.6e-08
EBFKHPNK_00837 5e-77
EBFKHPNK_00843 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
EBFKHPNK_00844 5.8e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
EBFKHPNK_00845 5.2e-181 cgeB S Spore maturation protein
EBFKHPNK_00846 4.1e-53 cgeA
EBFKHPNK_00847 7.3e-41 cgeC
EBFKHPNK_00848 1.6e-249 cgeD M maturation of the outermost layer of the spore
EBFKHPNK_00849 3.7e-145 yiiD K acetyltransferase
EBFKHPNK_00851 1.1e-64 yosT L Bacterial transcription activator, effector binding domain
EBFKHPNK_00852 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EBFKHPNK_00853 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBFKHPNK_00854 4e-122 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EBFKHPNK_00855 5.1e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
EBFKHPNK_00856 2.3e-159 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
EBFKHPNK_00857 7.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
EBFKHPNK_00858 2.4e-46 yokU S YokU-like protein, putative antitoxin
EBFKHPNK_00859 4.1e-36 yozE S Belongs to the UPF0346 family
EBFKHPNK_00860 4.9e-125 yodN
EBFKHPNK_00862 6.2e-24 yozD S YozD-like protein
EBFKHPNK_00863 9.5e-104 yodM 3.6.1.27 I Acid phosphatase homologues
EBFKHPNK_00864 3.3e-55 yodL S YodL-like
EBFKHPNK_00866 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
EBFKHPNK_00867 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EBFKHPNK_00868 4.3e-34 yodI
EBFKHPNK_00869 6.3e-128 yodH Q Methyltransferase
EBFKHPNK_00870 6.1e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
EBFKHPNK_00871 2.6e-132 yydK K Transcriptional regulator
EBFKHPNK_00872 1.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EBFKHPNK_00873 3.5e-277 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
EBFKHPNK_00874 1.3e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBFKHPNK_00875 1.4e-19 S Protein of unknown function (DUF3311)
EBFKHPNK_00876 3.8e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
EBFKHPNK_00877 5.7e-109 mhqD S Carboxylesterase
EBFKHPNK_00878 1.7e-105 yodC C nitroreductase
EBFKHPNK_00879 3e-56 yodB K transcriptional
EBFKHPNK_00880 1.2e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
EBFKHPNK_00881 1.6e-67 yodA S tautomerase
EBFKHPNK_00883 4.7e-79 yozR S COG0071 Molecular chaperone (small heat shock protein)
EBFKHPNK_00884 6.6e-162 rarD S -transporter
EBFKHPNK_00885 4.9e-23
EBFKHPNK_00886 9.7e-61 yojF S Protein of unknown function (DUF1806)
EBFKHPNK_00887 2.5e-126 yojG S deacetylase
EBFKHPNK_00888 2.9e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EBFKHPNK_00889 4.8e-241 norM V Multidrug efflux pump
EBFKHPNK_00891 2.2e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EBFKHPNK_00892 1.5e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
EBFKHPNK_00893 4.7e-227 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EBFKHPNK_00894 3.8e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EBFKHPNK_00895 3.5e-163 yojN S ATPase family associated with various cellular activities (AAA)
EBFKHPNK_00896 0.0 yojO P Von Willebrand factor
EBFKHPNK_00897 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EBFKHPNK_00898 2.7e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EBFKHPNK_00899 5.3e-141 S Metallo-beta-lactamase superfamily
EBFKHPNK_00900 2.7e-161 yocS S -transporter
EBFKHPNK_00901 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EBFKHPNK_00902 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
EBFKHPNK_00903 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
EBFKHPNK_00904 3.7e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
EBFKHPNK_00905 1.6e-31 yozC
EBFKHPNK_00907 2.4e-56 yozO S Bacterial PH domain
EBFKHPNK_00908 8.5e-37 yocN
EBFKHPNK_00909 1.4e-43 yozN
EBFKHPNK_00910 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
EBFKHPNK_00911 2.2e-08 yocN
EBFKHPNK_00912 1e-09 yocL
EBFKHPNK_00913 1.9e-54 dksA T general stress protein
EBFKHPNK_00915 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EBFKHPNK_00916 0.0 recQ 3.6.4.12 L DNA helicase
EBFKHPNK_00917 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
EBFKHPNK_00919 4.9e-187 yocD 3.4.17.13 V peptidase S66
EBFKHPNK_00920 7.3e-94 yocC
EBFKHPNK_00921 1.5e-141 yocB J Protein required for attachment to host cells
EBFKHPNK_00922 2.8e-91 yozB S membrane
EBFKHPNK_00923 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EBFKHPNK_00924 3.4e-55 czrA K transcriptional
EBFKHPNK_00925 2.4e-92 yobW
EBFKHPNK_00926 2.3e-133 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
EBFKHPNK_00927 2.2e-94 yobS K Transcriptional regulator
EBFKHPNK_00928 7.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
EBFKHPNK_00929 1.1e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
EBFKHPNK_00930 8.6e-157 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EBFKHPNK_00931 1.5e-85 S SMI1-KNR4 cell-wall
EBFKHPNK_00932 3.9e-44
EBFKHPNK_00933 5.6e-98 hpr K helix_turn_helix multiple antibiotic resistance protein
EBFKHPNK_00935 3.1e-25 yoaF
EBFKHPNK_00936 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EBFKHPNK_00937 5.7e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBFKHPNK_00938 4.5e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
EBFKHPNK_00939 1.5e-204 yoaB EGP Major facilitator Superfamily
EBFKHPNK_00940 5.1e-139 yoxB
EBFKHPNK_00941 2.6e-41 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EBFKHPNK_00942 8.9e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_00943 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EBFKHPNK_00944 8.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EBFKHPNK_00945 1.6e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EBFKHPNK_00946 3.9e-146 gltC K Transcriptional regulator
EBFKHPNK_00947 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
EBFKHPNK_00948 1.7e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EBFKHPNK_00949 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EBFKHPNK_00950 3.1e-153 gltR1 K Transcriptional regulator
EBFKHPNK_00951 6.6e-15 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EBFKHPNK_00952 1.8e-50 ybzH K Helix-turn-helix domain
EBFKHPNK_00953 2.1e-200 ybcL EGP Major facilitator Superfamily
EBFKHPNK_00954 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EBFKHPNK_00955 1.8e-34 yoeD G Helix-turn-helix domain
EBFKHPNK_00956 3.5e-97 L Integrase
EBFKHPNK_00958 1.1e-95 yoeB S IseA DL-endopeptidase inhibitor
EBFKHPNK_00959 7.9e-247 yoeA V MATE efflux family protein
EBFKHPNK_00960 1.1e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
EBFKHPNK_00961 1.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
EBFKHPNK_00962 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_00963 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_00964 1.4e-43 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_00965 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_00966 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_00967 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
EBFKHPNK_00968 4.1e-65 yngL S Protein of unknown function (DUF1360)
EBFKHPNK_00969 5.9e-304 yngK T Glycosyl hydrolase-like 10
EBFKHPNK_00970 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
EBFKHPNK_00971 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EBFKHPNK_00972 5.5e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
EBFKHPNK_00973 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
EBFKHPNK_00974 5.6e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
EBFKHPNK_00975 8.9e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EBFKHPNK_00976 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EBFKHPNK_00977 3.2e-104 yngC S SNARE associated Golgi protein
EBFKHPNK_00978 1.5e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EBFKHPNK_00979 3.7e-72 yngA S membrane
EBFKHPNK_00980 2.8e-145 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EBFKHPNK_00981 2.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EBFKHPNK_00982 1.9e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EBFKHPNK_00983 5.7e-129 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EBFKHPNK_00984 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EBFKHPNK_00985 2.3e-223 bioI 1.14.14.46 C Cytochrome P450
EBFKHPNK_00986 6.9e-254 yxjC EG COG2610 H gluconate symporter and related permeases
EBFKHPNK_00987 4.9e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EBFKHPNK_00988 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EBFKHPNK_00989 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EBFKHPNK_00990 6.6e-218 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EBFKHPNK_00991 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_00992 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_00993 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_00994 1.1e-284 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
EBFKHPNK_00995 4.1e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
EBFKHPNK_00996 3.4e-129 T Transcriptional regulatory protein, C terminal
EBFKHPNK_00997 5e-233 T PhoQ Sensor
EBFKHPNK_00998 4.8e-51 S Domain of unknown function (DUF4870)
EBFKHPNK_00999 7.8e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
EBFKHPNK_01000 3.2e-214 S Platelet-activating factor acetylhydrolase, isoform II
EBFKHPNK_01001 6.3e-304 yndJ S YndJ-like protein
EBFKHPNK_01002 2.6e-77 yndH S Domain of unknown function (DUF4166)
EBFKHPNK_01003 8.4e-156 yndG S DoxX-like family
EBFKHPNK_01004 8.6e-224 exuT G Sugar (and other) transporter
EBFKHPNK_01005 1.4e-181 kdgR_1 K transcriptional
EBFKHPNK_01006 2e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_01007 7e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
EBFKHPNK_01008 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
EBFKHPNK_01009 3.4e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
EBFKHPNK_01010 1.3e-179 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
EBFKHPNK_01011 1.7e-249 agcS E Sodium alanine symporter
EBFKHPNK_01012 5.1e-41 ynfC
EBFKHPNK_01013 6e-13
EBFKHPNK_01014 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EBFKHPNK_01015 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EBFKHPNK_01016 1.5e-68 yccU S CoA-binding protein
EBFKHPNK_01017 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EBFKHPNK_01018 1.3e-50 yneR S Belongs to the HesB IscA family
EBFKHPNK_01019 9.9e-54 yneQ
EBFKHPNK_01020 8.3e-75 yneP S Thioesterase-like superfamily
EBFKHPNK_01021 7.1e-18 tlp S Belongs to the Tlp family
EBFKHPNK_01023 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EBFKHPNK_01024 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EBFKHPNK_01025 7.5e-15 sspO S Belongs to the SspO family
EBFKHPNK_01026 2.3e-19 sspP S Belongs to the SspP family
EBFKHPNK_01027 3.2e-62 hspX O Spore coat protein
EBFKHPNK_01028 8.5e-75 yneK S Protein of unknown function (DUF2621)
EBFKHPNK_01029 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
EBFKHPNK_01030 1e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
EBFKHPNK_01031 1.7e-125 ccdA O cytochrome c biogenesis protein
EBFKHPNK_01032 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
EBFKHPNK_01033 2.3e-28 yneF S UPF0154 protein
EBFKHPNK_01034 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
EBFKHPNK_01035 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EBFKHPNK_01036 9.8e-33 ynzC S UPF0291 protein
EBFKHPNK_01037 3.5e-112 yneB L resolvase
EBFKHPNK_01038 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EBFKHPNK_01039 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EBFKHPNK_01040 4.6e-12 yoaW
EBFKHPNK_01041 2.4e-72 yndM S Protein of unknown function (DUF2512)
EBFKHPNK_01042 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
EBFKHPNK_01043 1.6e-07
EBFKHPNK_01044 1.2e-146 yndL S Replication protein
EBFKHPNK_01045 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EBFKHPNK_01046 0.0 yobO M Pectate lyase superfamily protein
EBFKHPNK_01048 3.5e-94 yvgO
EBFKHPNK_01049 3.4e-65 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EBFKHPNK_01051 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
EBFKHPNK_01052 6e-202 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBFKHPNK_01053 1.1e-118 ynaE S Domain of unknown function (DUF3885)
EBFKHPNK_01054 6e-80 J Acetyltransferase (GNAT) domain
EBFKHPNK_01055 3.1e-141 yoaP 3.1.3.18 K YoaP-like
EBFKHPNK_01057 3.8e-20 yoaW
EBFKHPNK_01058 1.9e-16
EBFKHPNK_01059 3.9e-08 ccmM S Bacterial transferase hexapeptide (six repeats)
EBFKHPNK_01060 1.1e-186 adhP 1.1.1.1 C alcohol dehydrogenase
EBFKHPNK_01061 7.8e-55 dinB S DinB family
EBFKHPNK_01062 5.4e-17
EBFKHPNK_01065 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
EBFKHPNK_01066 3.1e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
EBFKHPNK_01067 3.5e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
EBFKHPNK_01068 5.4e-217 xylR GK ROK family
EBFKHPNK_01069 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EBFKHPNK_01070 9.6e-253 xynT G MFS/sugar transport protein
EBFKHPNK_01071 2.7e-210 mrjp G Major royal jelly protein
EBFKHPNK_01072 5.3e-66 yokK S SMI1 / KNR4 family
EBFKHPNK_01073 2.4e-51 S SMI1-KNR4 cell-wall
EBFKHPNK_01074 2.5e-160 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EBFKHPNK_01075 1.6e-216 hcaT 1.5.1.2 EGP Major facilitator Superfamily
EBFKHPNK_01076 1.1e-90 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EBFKHPNK_01077 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EBFKHPNK_01078 2.8e-174 isp O Belongs to the peptidase S8 family
EBFKHPNK_01079 6.6e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EBFKHPNK_01080 2.1e-132 ykoC P Cobalt transport protein
EBFKHPNK_01081 6.1e-307 P ABC transporter, ATP-binding protein
EBFKHPNK_01082 1e-97 ykoE S ABC-type cobalt transport system, permease component
EBFKHPNK_01083 3.9e-245 ydhD M Glycosyl hydrolase
EBFKHPNK_01085 6.5e-238 mgtE P Acts as a magnesium transporter
EBFKHPNK_01086 5.4e-53 tnrA K transcriptional
EBFKHPNK_01087 1.9e-16
EBFKHPNK_01088 3.1e-26 ykoL
EBFKHPNK_01089 1.1e-80 ykoM K transcriptional
EBFKHPNK_01090 3.7e-99 ykoP G polysaccharide deacetylase
EBFKHPNK_01091 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
EBFKHPNK_01092 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EBFKHPNK_01093 4.1e-101 ykoX S membrane-associated protein
EBFKHPNK_01094 3e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EBFKHPNK_01095 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBFKHPNK_01096 1.1e-119 rsgI S Anti-sigma factor N-terminus
EBFKHPNK_01097 2.5e-26 sspD S small acid-soluble spore protein
EBFKHPNK_01098 1.2e-123 ykrK S Domain of unknown function (DUF1836)
EBFKHPNK_01099 4.1e-156 htpX O Belongs to the peptidase M48B family
EBFKHPNK_01100 3.4e-239 ktrB P COG0168 Trk-type K transport systems, membrane components
EBFKHPNK_01101 1.5e-113 ydfR S Protein of unknown function (DUF421)
EBFKHPNK_01102 7.9e-24 ykzE
EBFKHPNK_01103 2e-191 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
EBFKHPNK_01104 0.0 kinE 2.7.13.3 T Histidine kinase
EBFKHPNK_01105 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EBFKHPNK_01107 4.4e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EBFKHPNK_01108 1e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EBFKHPNK_01109 2.3e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EBFKHPNK_01110 2.2e-229 mtnE 2.6.1.83 E Aminotransferase
EBFKHPNK_01111 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EBFKHPNK_01112 1.9e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EBFKHPNK_01113 4e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EBFKHPNK_01114 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EBFKHPNK_01115 3.4e-10 S Spo0E like sporulation regulatory protein
EBFKHPNK_01116 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
EBFKHPNK_01117 7.2e-77 ykvE K transcriptional
EBFKHPNK_01118 2.7e-127 motB N Flagellar motor protein
EBFKHPNK_01119 1.1e-136 motA N flagellar motor
EBFKHPNK_01120 0.0 clpE O Belongs to the ClpA ClpB family
EBFKHPNK_01121 5.4e-184 ykvI S membrane
EBFKHPNK_01122 1.1e-190
EBFKHPNK_01123 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EBFKHPNK_01124 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
EBFKHPNK_01125 1.9e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EBFKHPNK_01126 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBFKHPNK_01127 7.1e-59 ykvN K HxlR-like helix-turn-helix
EBFKHPNK_01128 5.9e-132 IQ Enoyl-(Acyl carrier protein) reductase
EBFKHPNK_01129 4.1e-19 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EBFKHPNK_01130 3e-212 ykvP 3.5.1.28 M Glycosyl transferases group 1
EBFKHPNK_01131 1.3e-34 3.5.1.104 M LysM domain
EBFKHPNK_01132 1.2e-161 G Glycosyl hydrolases family 18
EBFKHPNK_01134 4.2e-43 ykvR S Protein of unknown function (DUF3219)
EBFKHPNK_01135 7.8e-25 ykvS S protein conserved in bacteria
EBFKHPNK_01136 2.3e-27
EBFKHPNK_01137 2.4e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
EBFKHPNK_01138 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EBFKHPNK_01139 2.7e-88 stoA CO thiol-disulfide
EBFKHPNK_01140 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EBFKHPNK_01141 3.7e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EBFKHPNK_01143 5.1e-176 ykvZ 5.1.1.1 K Transcriptional regulator
EBFKHPNK_01144 5.1e-156 glcT K antiterminator
EBFKHPNK_01145 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EBFKHPNK_01146 2.1e-39 ptsH G phosphocarrier protein HPr
EBFKHPNK_01147 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBFKHPNK_01148 6.1e-38 splA S Transcriptional regulator
EBFKHPNK_01149 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
EBFKHPNK_01150 6.5e-263 mcpC NT chemotaxis protein
EBFKHPNK_01151 4.3e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EBFKHPNK_01152 5.6e-117 ykwD J protein with SCP PR1 domains
EBFKHPNK_01153 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
EBFKHPNK_01154 2.6e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
EBFKHPNK_01155 8.7e-215 patA 2.6.1.1 E Aminotransferase
EBFKHPNK_01156 2.3e-09
EBFKHPNK_01157 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
EBFKHPNK_01158 1.2e-82 ykyB S YkyB-like protein
EBFKHPNK_01159 7.8e-241 ykuC EGP Major facilitator Superfamily
EBFKHPNK_01160 1.2e-88 ykuD S protein conserved in bacteria
EBFKHPNK_01161 1.5e-155 ykuE S Metallophosphoesterase
EBFKHPNK_01162 4.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_01164 3.3e-233 ykuI T Diguanylate phosphodiesterase
EBFKHPNK_01165 3.9e-37 ykuJ S protein conserved in bacteria
EBFKHPNK_01166 4.9e-93 ykuK S Ribonuclease H-like
EBFKHPNK_01167 2.1e-25 ykzF S Antirepressor AbbA
EBFKHPNK_01168 1e-75 ykuL S CBS domain
EBFKHPNK_01169 4.6e-168 ccpC K Transcriptional regulator
EBFKHPNK_01170 1.3e-89 fld C Flavodoxin
EBFKHPNK_01171 2.7e-168 ykuO
EBFKHPNK_01172 2.3e-78 fld C Flavodoxin
EBFKHPNK_01173 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EBFKHPNK_01174 5.3e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EBFKHPNK_01175 4.8e-38 ykuS S Belongs to the UPF0180 family
EBFKHPNK_01176 4.9e-140 ykuT M Mechanosensitive ion channel
EBFKHPNK_01177 5.5e-80 ykuV CO thiol-disulfide
EBFKHPNK_01178 1.5e-98 rok K Repressor of ComK
EBFKHPNK_01179 8.6e-163 yknT
EBFKHPNK_01180 4.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EBFKHPNK_01181 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EBFKHPNK_01182 6.4e-243 moeA 2.10.1.1 H molybdopterin
EBFKHPNK_01183 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
EBFKHPNK_01184 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
EBFKHPNK_01185 5.7e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EBFKHPNK_01186 6.4e-104 yknW S Yip1 domain
EBFKHPNK_01187 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EBFKHPNK_01188 6.1e-123 macB V ABC transporter, ATP-binding protein
EBFKHPNK_01189 3.2e-212 yknZ V ABC transporter (permease)
EBFKHPNK_01190 1.2e-132 fruR K Transcriptional regulator
EBFKHPNK_01191 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
EBFKHPNK_01192 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EBFKHPNK_01193 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EBFKHPNK_01194 1.5e-37 ykoA
EBFKHPNK_01195 6.4e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EBFKHPNK_01196 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBFKHPNK_01197 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EBFKHPNK_01198 5.5e-12 S Uncharacterized protein YkpC
EBFKHPNK_01199 6.9e-184 mreB D Rod-share determining protein MreBH
EBFKHPNK_01200 2.1e-45 abrB K of stationary sporulation gene expression
EBFKHPNK_01201 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
EBFKHPNK_01202 1.6e-149 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
EBFKHPNK_01203 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
EBFKHPNK_01204 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EBFKHPNK_01205 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EBFKHPNK_01206 8.2e-31 ykzG S Belongs to the UPF0356 family
EBFKHPNK_01207 4.4e-146 ykrA S hydrolases of the HAD superfamily
EBFKHPNK_01208 4.4e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EBFKHPNK_01210 5.9e-104 recN L Putative cell-wall binding lipoprotein
EBFKHPNK_01211 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EBFKHPNK_01212 0.0 Q Polyketide synthase of type I
EBFKHPNK_01213 0.0 Q polyketide synthase
EBFKHPNK_01214 0.0 Q Polyketide synthase of type I
EBFKHPNK_01215 0.0 Q Polyketide synthase of type I
EBFKHPNK_01216 0.0 Q Polyketide synthase of type I
EBFKHPNK_01217 0.0 Q Polyketide synthase of type I
EBFKHPNK_01218 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
EBFKHPNK_01219 6e-210 V Beta-lactamase
EBFKHPNK_01220 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EBFKHPNK_01221 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EBFKHPNK_01222 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EBFKHPNK_01223 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EBFKHPNK_01224 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
EBFKHPNK_01225 3.5e-138 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
EBFKHPNK_01226 3.5e-277 speA 4.1.1.19 E Arginine
EBFKHPNK_01227 1.6e-42 yktA S Belongs to the UPF0223 family
EBFKHPNK_01228 9.2e-118 yktB S Belongs to the UPF0637 family
EBFKHPNK_01229 6.3e-24 ykzI
EBFKHPNK_01230 2.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
EBFKHPNK_01231 1.8e-83 ykzC S Acetyltransferase (GNAT) family
EBFKHPNK_01232 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
EBFKHPNK_01233 1.7e-13 sigC S Putative zinc-finger
EBFKHPNK_01234 7e-38 ylaE
EBFKHPNK_01235 6.7e-24 S Family of unknown function (DUF5325)
EBFKHPNK_01236 0.0 typA T GTP-binding protein TypA
EBFKHPNK_01237 1.7e-48 ylaH S YlaH-like protein
EBFKHPNK_01238 1e-33 ylaI S protein conserved in bacteria
EBFKHPNK_01239 3.3e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EBFKHPNK_01240 2.2e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
EBFKHPNK_01241 3.2e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EBFKHPNK_01242 5.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
EBFKHPNK_01243 8.7e-44 ylaN S Belongs to the UPF0358 family
EBFKHPNK_01244 1.1e-212 ftsW D Belongs to the SEDS family
EBFKHPNK_01245 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EBFKHPNK_01246 2.9e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EBFKHPNK_01247 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EBFKHPNK_01248 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EBFKHPNK_01249 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBFKHPNK_01250 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EBFKHPNK_01251 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EBFKHPNK_01252 2.8e-165 ctaG S cytochrome c oxidase
EBFKHPNK_01253 8.5e-60 ylbA S YugN-like family
EBFKHPNK_01254 6.3e-73 ylbB T COG0517 FOG CBS domain
EBFKHPNK_01255 1.5e-197 ylbC S protein with SCP PR1 domains
EBFKHPNK_01256 1.9e-55 ylbD S Putative coat protein
EBFKHPNK_01257 8.8e-37 ylbE S YlbE-like protein
EBFKHPNK_01258 1.2e-71 ylbF S Belongs to the UPF0342 family
EBFKHPNK_01259 7.2e-43 ylbG S UPF0298 protein
EBFKHPNK_01261 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
EBFKHPNK_01262 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBFKHPNK_01263 1.7e-216 ylbJ S Sporulation integral membrane protein YlbJ
EBFKHPNK_01264 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
EBFKHPNK_01265 5.5e-189 ylbL T Belongs to the peptidase S16 family
EBFKHPNK_01266 2.3e-229 ylbM S Belongs to the UPF0348 family
EBFKHPNK_01267 3.3e-89 yceD S metal-binding, possibly nucleic acid-binding protein
EBFKHPNK_01268 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EBFKHPNK_01269 7.6e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EBFKHPNK_01270 3.1e-89 ylbP K n-acetyltransferase
EBFKHPNK_01271 3.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBFKHPNK_01272 2.8e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EBFKHPNK_01273 1.2e-77 mraZ K Belongs to the MraZ family
EBFKHPNK_01274 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EBFKHPNK_01275 1.1e-51 ftsL D Essential cell division protein
EBFKHPNK_01276 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EBFKHPNK_01277 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
EBFKHPNK_01278 4.4e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EBFKHPNK_01279 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBFKHPNK_01280 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EBFKHPNK_01281 2.2e-185 spoVE D Belongs to the SEDS family
EBFKHPNK_01282 4.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EBFKHPNK_01283 3.7e-168 murB 1.3.1.98 M cell wall formation
EBFKHPNK_01284 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EBFKHPNK_01285 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EBFKHPNK_01286 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EBFKHPNK_01287 0.0 bpr O COG1404 Subtilisin-like serine proteases
EBFKHPNK_01288 3.7e-160 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EBFKHPNK_01289 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBFKHPNK_01290 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBFKHPNK_01291 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EBFKHPNK_01292 4.7e-190 argE 3.5.1.16 E Acetylornithine deacetylase
EBFKHPNK_01293 6.6e-53 argE 3.5.1.16 E Acetylornithine deacetylase
EBFKHPNK_01294 2.2e-38 ylmC S sporulation protein
EBFKHPNK_01295 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
EBFKHPNK_01296 2.5e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EBFKHPNK_01297 1.8e-59 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EBFKHPNK_01298 5.2e-41 yggT S membrane
EBFKHPNK_01299 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
EBFKHPNK_01300 8.9e-68 divIVA D Cell division initiation protein
EBFKHPNK_01301 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EBFKHPNK_01302 3.4e-64 dksA T COG1734 DnaK suppressor protein
EBFKHPNK_01303 2e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBFKHPNK_01304 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EBFKHPNK_01305 3e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EBFKHPNK_01306 8e-233 pyrP F Xanthine uracil
EBFKHPNK_01307 4.1e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EBFKHPNK_01308 3.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EBFKHPNK_01309 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EBFKHPNK_01310 0.0 carB 6.3.5.5 F Belongs to the CarB family
EBFKHPNK_01311 1.4e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EBFKHPNK_01312 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EBFKHPNK_01313 1.2e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EBFKHPNK_01314 6.6e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EBFKHPNK_01316 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
EBFKHPNK_01317 7e-179 cysP P phosphate transporter
EBFKHPNK_01318 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
EBFKHPNK_01319 3.9e-110 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
EBFKHPNK_01320 5.3e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EBFKHPNK_01321 9.9e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
EBFKHPNK_01322 5.5e-78 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
EBFKHPNK_01323 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EBFKHPNK_01324 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
EBFKHPNK_01325 5e-154 yloC S stress-induced protein
EBFKHPNK_01326 1.5e-40 ylzA S Belongs to the UPF0296 family
EBFKHPNK_01327 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EBFKHPNK_01328 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EBFKHPNK_01329 9.7e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EBFKHPNK_01330 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBFKHPNK_01331 2.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EBFKHPNK_01332 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBFKHPNK_01333 2.3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EBFKHPNK_01334 3.4e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EBFKHPNK_01335 1.7e-139 stp 3.1.3.16 T phosphatase
EBFKHPNK_01336 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EBFKHPNK_01337 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EBFKHPNK_01338 2.3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EBFKHPNK_01339 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
EBFKHPNK_01340 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EBFKHPNK_01341 5.5e-59 asp S protein conserved in bacteria
EBFKHPNK_01342 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
EBFKHPNK_01343 2.1e-117 sdaAB 4.3.1.17 E L-serine dehydratase
EBFKHPNK_01344 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
EBFKHPNK_01345 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EBFKHPNK_01346 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EBFKHPNK_01347 1.1e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EBFKHPNK_01348 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EBFKHPNK_01349 4.6e-129 IQ reductase
EBFKHPNK_01350 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBFKHPNK_01351 2.6e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EBFKHPNK_01352 0.0 smc D Required for chromosome condensation and partitioning
EBFKHPNK_01353 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EBFKHPNK_01354 1.2e-140 S Phosphotransferase enzyme family
EBFKHPNK_01355 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EBFKHPNK_01356 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EBFKHPNK_01357 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EBFKHPNK_01358 1.7e-35 ylqC S Belongs to the UPF0109 family
EBFKHPNK_01359 3.7e-61 ylqD S YlqD protein
EBFKHPNK_01360 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBFKHPNK_01361 6.4e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EBFKHPNK_01362 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EBFKHPNK_01363 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EBFKHPNK_01364 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EBFKHPNK_01365 1.4e-306 ylqG
EBFKHPNK_01366 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
EBFKHPNK_01367 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EBFKHPNK_01368 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EBFKHPNK_01369 1.2e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
EBFKHPNK_01370 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBFKHPNK_01371 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EBFKHPNK_01372 7.2e-172 xerC L tyrosine recombinase XerC
EBFKHPNK_01373 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EBFKHPNK_01374 1.6e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EBFKHPNK_01375 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EBFKHPNK_01376 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EBFKHPNK_01377 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
EBFKHPNK_01378 2.5e-31 fliE N Flagellar hook-basal body
EBFKHPNK_01379 1.4e-263 fliF N The M ring may be actively involved in energy transduction
EBFKHPNK_01380 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EBFKHPNK_01381 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
EBFKHPNK_01382 5.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EBFKHPNK_01383 4.5e-71 fliJ N Flagellar biosynthesis chaperone
EBFKHPNK_01384 4.4e-48 ylxF S MgtE intracellular N domain
EBFKHPNK_01385 2.7e-204 fliK N Flagellar hook-length control protein
EBFKHPNK_01386 1.4e-72 flgD N Flagellar basal body rod modification protein
EBFKHPNK_01387 4e-139 flgG N Flagellar basal body rod
EBFKHPNK_01388 7.8e-57 fliL N Controls the rotational direction of flagella during chemotaxis
EBFKHPNK_01389 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EBFKHPNK_01390 1.8e-185 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EBFKHPNK_01391 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
EBFKHPNK_01392 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
EBFKHPNK_01393 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
EBFKHPNK_01394 2e-37 fliQ N Role in flagellar biosynthesis
EBFKHPNK_01395 8.9e-131 fliR N Flagellar biosynthetic protein FliR
EBFKHPNK_01396 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBFKHPNK_01397 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EBFKHPNK_01398 1.4e-193 flhF N Flagellar biosynthesis regulator FlhF
EBFKHPNK_01399 5.4e-156 flhG D Belongs to the ParA family
EBFKHPNK_01400 6.6e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EBFKHPNK_01401 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
EBFKHPNK_01402 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
EBFKHPNK_01403 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EBFKHPNK_01404 8.6e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EBFKHPNK_01405 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBFKHPNK_01406 8.1e-55 ylxL
EBFKHPNK_01407 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
EBFKHPNK_01408 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBFKHPNK_01409 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EBFKHPNK_01410 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EBFKHPNK_01411 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EBFKHPNK_01412 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
EBFKHPNK_01413 1.9e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EBFKHPNK_01414 1.5e-233 rasP M zinc metalloprotease
EBFKHPNK_01415 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EBFKHPNK_01416 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EBFKHPNK_01417 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
EBFKHPNK_01418 5.4e-206 nusA K Participates in both transcription termination and antitermination
EBFKHPNK_01419 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
EBFKHPNK_01420 1.8e-47 ylxQ J ribosomal protein
EBFKHPNK_01421 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBFKHPNK_01422 3.9e-44 ylxP S protein conserved in bacteria
EBFKHPNK_01423 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EBFKHPNK_01424 5.2e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EBFKHPNK_01425 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EBFKHPNK_01426 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBFKHPNK_01427 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EBFKHPNK_01428 4e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
EBFKHPNK_01429 3.6e-235 pepR S Belongs to the peptidase M16 family
EBFKHPNK_01430 2.6e-42 ymxH S YlmC YmxH family
EBFKHPNK_01431 3.6e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
EBFKHPNK_01432 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EBFKHPNK_01433 2.2e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EBFKHPNK_01434 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EBFKHPNK_01435 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBFKHPNK_01436 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EBFKHPNK_01437 6.6e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
EBFKHPNK_01438 6.3e-31 S YlzJ-like protein
EBFKHPNK_01439 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EBFKHPNK_01440 1.8e-133 ymfC K Transcriptional regulator
EBFKHPNK_01441 2.4e-229 ymfD EGP Major facilitator Superfamily
EBFKHPNK_01442 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
EBFKHPNK_01443 0.0 ydgH S drug exporters of the RND superfamily
EBFKHPNK_01444 3.6e-238 ymfF S Peptidase M16
EBFKHPNK_01445 4.9e-243 ymfH S zinc protease
EBFKHPNK_01446 3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EBFKHPNK_01447 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
EBFKHPNK_01448 3.5e-143 ymfK S Protein of unknown function (DUF3388)
EBFKHPNK_01449 1.7e-125 ymfM S protein conserved in bacteria
EBFKHPNK_01450 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBFKHPNK_01451 3.8e-232 cinA 3.5.1.42 S Belongs to the CinA family
EBFKHPNK_01452 1.3e-185 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBFKHPNK_01453 3.9e-194 pbpX V Beta-lactamase
EBFKHPNK_01454 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
EBFKHPNK_01455 4.9e-153 ymdB S protein conserved in bacteria
EBFKHPNK_01456 1.2e-36 spoVS S Stage V sporulation protein S
EBFKHPNK_01457 2.1e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EBFKHPNK_01458 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EBFKHPNK_01459 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBFKHPNK_01460 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EBFKHPNK_01461 1.7e-88 cotE S Spore coat protein
EBFKHPNK_01462 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EBFKHPNK_01463 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EBFKHPNK_01464 9.1e-52 L Belongs to the 'phage' integrase family
EBFKHPNK_01465 9.1e-31
EBFKHPNK_01468 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
EBFKHPNK_01469 9.8e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EBFKHPNK_01470 3.9e-184 pksD Q Acyl transferase domain
EBFKHPNK_01471 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EBFKHPNK_01472 1.9e-34 acpK IQ Phosphopantetheine attachment site
EBFKHPNK_01473 2.8e-243 pksG 2.3.3.10 I synthase
EBFKHPNK_01474 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
EBFKHPNK_01475 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EBFKHPNK_01476 0.0 rhiB IQ polyketide synthase
EBFKHPNK_01477 0.0 Q Polyketide synthase of type I
EBFKHPNK_01478 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
EBFKHPNK_01479 0.0 dhbF IQ polyketide synthase
EBFKHPNK_01480 0.0 pks13 HQ Beta-ketoacyl synthase
EBFKHPNK_01481 2e-230 cypA C Cytochrome P450
EBFKHPNK_01482 1.3e-78 nucB M Deoxyribonuclease NucA/NucB
EBFKHPNK_01483 3.6e-118 yoaK S Membrane
EBFKHPNK_01484 4.5e-61 ymzB
EBFKHPNK_01485 1.2e-255 aprX O Belongs to the peptidase S8 family
EBFKHPNK_01487 4.1e-127 ymaC S Replication protein
EBFKHPNK_01488 6e-79 ymaD O redox protein, regulator of disulfide bond formation
EBFKHPNK_01489 5.2e-54 ebrB P Small Multidrug Resistance protein
EBFKHPNK_01490 3.1e-48 ebrA P Small Multidrug Resistance protein
EBFKHPNK_01492 1.4e-47 ymaF S YmaF family
EBFKHPNK_01493 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EBFKHPNK_01494 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EBFKHPNK_01495 9.4e-43
EBFKHPNK_01496 1.8e-20 ymzA
EBFKHPNK_01497 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
EBFKHPNK_01498 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBFKHPNK_01499 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBFKHPNK_01500 1.2e-109 ymaB S MutT family
EBFKHPNK_01501 4.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EBFKHPNK_01502 1.3e-176 spoVK O stage V sporulation protein K
EBFKHPNK_01503 4.2e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBFKHPNK_01504 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EBFKHPNK_01505 4.3e-68 glnR K transcriptional
EBFKHPNK_01506 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
EBFKHPNK_01508 2.9e-30
EBFKHPNK_01509 1.9e-90 yokH G SMI1 / KNR4 family
EBFKHPNK_01512 3.4e-129
EBFKHPNK_01513 3.4e-11 ywlA S Uncharacterised protein family (UPF0715)
EBFKHPNK_01514 4e-12
EBFKHPNK_01515 1.2e-49 FG Scavenger mRNA decapping enzyme C-term binding
EBFKHPNK_01516 1.5e-72 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
EBFKHPNK_01518 1.3e-165 bla 3.5.2.6 V beta-lactamase
EBFKHPNK_01519 1.9e-46 yjcS S Antibiotic biosynthesis monooxygenase
EBFKHPNK_01520 7e-251 yfjF EGP Belongs to the major facilitator superfamily
EBFKHPNK_01521 7.9e-82 napB K helix_turn_helix multiple antibiotic resistance protein
EBFKHPNK_01522 2.3e-220 ganA 3.2.1.89 G arabinogalactan
EBFKHPNK_01523 2.5e-291 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EBFKHPNK_01524 4.8e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EBFKHPNK_01525 2.1e-216 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EBFKHPNK_01526 4.7e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EBFKHPNK_01527 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
EBFKHPNK_01528 1.5e-282 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
EBFKHPNK_01529 1.3e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
EBFKHPNK_01530 4.4e-126 5.4.2.6 S Haloacid dehalogenase-like hydrolase
EBFKHPNK_01533 1.1e-105 yhiD S MgtC SapB transporter
EBFKHPNK_01535 8.3e-21 yjfB S Putative motility protein
EBFKHPNK_01536 5.9e-70 T PhoQ Sensor
EBFKHPNK_01537 8.3e-102 yjgB S Domain of unknown function (DUF4309)
EBFKHPNK_01538 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EBFKHPNK_01539 4.3e-92 yjgD S Protein of unknown function (DUF1641)
EBFKHPNK_01540 7.2e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
EBFKHPNK_01541 3e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EBFKHPNK_01542 2e-28
EBFKHPNK_01543 3.1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EBFKHPNK_01544 3.2e-123 ybbM S transport system, permease component
EBFKHPNK_01545 1.4e-130 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
EBFKHPNK_01546 1.1e-178 yjlA EG Putative multidrug resistance efflux transporter
EBFKHPNK_01547 1.2e-91 yjlB S Cupin domain
EBFKHPNK_01548 7e-66 yjlC S Protein of unknown function (DUF1641)
EBFKHPNK_01549 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
EBFKHPNK_01550 1.5e-277 uxaC 5.3.1.12 G glucuronate isomerase
EBFKHPNK_01551 1.5e-253 yjmB G symporter YjmB
EBFKHPNK_01552 3.4e-183 exuR K transcriptional
EBFKHPNK_01553 1.1e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
EBFKHPNK_01554 2.1e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
EBFKHPNK_01555 3.9e-131 MA20_18170 S membrane transporter protein
EBFKHPNK_01556 6.2e-79 yjoA S DinB family
EBFKHPNK_01557 4.9e-215 S response regulator aspartate phosphatase
EBFKHPNK_01559 5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EBFKHPNK_01560 4.7e-61 yjqA S Bacterial PH domain
EBFKHPNK_01561 3.3e-109 yjqB S phage-related replication protein
EBFKHPNK_01562 4.6e-149 ydbD P Catalase
EBFKHPNK_01563 1.3e-110 xkdA E IrrE N-terminal-like domain
EBFKHPNK_01564 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
EBFKHPNK_01566 2.2e-153 xkdC L Bacterial dnaA protein
EBFKHPNK_01569 2e-10 yqaO S Phage-like element PBSX protein XtrA
EBFKHPNK_01570 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EBFKHPNK_01571 1.2e-109 xtmA L phage terminase small subunit
EBFKHPNK_01572 1e-208 xtmB S phage terminase, large subunit
EBFKHPNK_01573 7.9e-242 yqbA S portal protein
EBFKHPNK_01574 9.8e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
EBFKHPNK_01575 1e-157 xkdG S Phage capsid family
EBFKHPNK_01576 5.7e-46 yqbG S Protein of unknown function (DUF3199)
EBFKHPNK_01577 9.3e-43 yqbH S Domain of unknown function (DUF3599)
EBFKHPNK_01578 5.3e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
EBFKHPNK_01579 4.9e-57 xkdJ
EBFKHPNK_01580 3.1e-14
EBFKHPNK_01581 1e-225 xkdK S Phage tail sheath C-terminal domain
EBFKHPNK_01582 2e-74 xkdM S Phage tail tube protein
EBFKHPNK_01583 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
EBFKHPNK_01584 3.4e-19
EBFKHPNK_01585 1e-190 xkdO L Transglycosylase SLT domain
EBFKHPNK_01586 6.6e-111 xkdP S Lysin motif
EBFKHPNK_01587 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
EBFKHPNK_01588 7.2e-32 xkdR S Protein of unknown function (DUF2577)
EBFKHPNK_01589 5.5e-58 xkdS S Protein of unknown function (DUF2634)
EBFKHPNK_01590 5.1e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EBFKHPNK_01591 2.2e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
EBFKHPNK_01592 1e-25
EBFKHPNK_01593 6.8e-186
EBFKHPNK_01595 1.7e-30 xkdX
EBFKHPNK_01596 1.8e-136 xepA
EBFKHPNK_01597 8.7e-38 xhlA S Haemolysin XhlA
EBFKHPNK_01598 1.3e-38 xhlB S SPP1 phage holin
EBFKHPNK_01599 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EBFKHPNK_01600 8.7e-23 spoIISB S Stage II sporulation protein SB
EBFKHPNK_01601 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
EBFKHPNK_01602 5.8e-175 pit P phosphate transporter
EBFKHPNK_01603 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
EBFKHPNK_01604 3.8e-243 steT E amino acid
EBFKHPNK_01605 1.2e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
EBFKHPNK_01606 4.4e-305 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EBFKHPNK_01607 2.9e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EBFKHPNK_01609 1.7e-206 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBFKHPNK_01610 4.6e-280 yubD P Major Facilitator Superfamily
EBFKHPNK_01612 6.5e-156 dppA E D-aminopeptidase
EBFKHPNK_01613 5.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBFKHPNK_01614 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBFKHPNK_01615 7.7e-191 dppD P Belongs to the ABC transporter superfamily
EBFKHPNK_01616 0.0 dppE E ABC transporter substrate-binding protein
EBFKHPNK_01617 6.4e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EBFKHPNK_01618 6.3e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
EBFKHPNK_01619 3.2e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EBFKHPNK_01620 9.6e-183 ykfD E Belongs to the ABC transporter superfamily
EBFKHPNK_01621 1.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
EBFKHPNK_01622 1.1e-158 ykgA E Amidinotransferase
EBFKHPNK_01623 4.1e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
EBFKHPNK_01624 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EBFKHPNK_01625 8.3e-53 ykkC P Multidrug resistance protein
EBFKHPNK_01626 3.4e-49 ykkD P Multidrug resistance protein
EBFKHPNK_01627 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EBFKHPNK_01628 3.5e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EBFKHPNK_01629 1.8e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EBFKHPNK_01630 1.3e-70 ohrA O Organic hydroperoxide resistance protein
EBFKHPNK_01631 9.7e-86 ohrR K COG1846 Transcriptional regulators
EBFKHPNK_01632 9.3e-71 ohrB O Organic hydroperoxide resistance protein
EBFKHPNK_01633 8.9e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EBFKHPNK_01635 9.9e-216 M Glycosyl transferase family 2
EBFKHPNK_01636 2.4e-69 M PFAM Collagen triple helix repeat (20 copies)
EBFKHPNK_01637 1.2e-131 yobL S Bacterial EndoU nuclease
EBFKHPNK_01638 3.1e-23
EBFKHPNK_01642 2.1e-08 S Cro/C1-type HTH DNA-binding domain
EBFKHPNK_01645 5.5e-35 S Domain of unknown function (DUF4917)
EBFKHPNK_01646 8.6e-11
EBFKHPNK_01647 2.2e-174 S Pfam Transposase IS66
EBFKHPNK_01651 1.6e-08
EBFKHPNK_01655 7.2e-96 C Na+/H+ antiporter family
EBFKHPNK_01656 3.3e-175 C Na+/H+ antiporter family
EBFKHPNK_01657 3.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
EBFKHPNK_01658 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EBFKHPNK_01659 1.2e-264 ygaK C Berberine and berberine like
EBFKHPNK_01661 2.4e-229 oppA5 E PFAM extracellular solute-binding protein family 5
EBFKHPNK_01662 1.6e-137 appB P Binding-protein-dependent transport system inner membrane component
EBFKHPNK_01663 2.4e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBFKHPNK_01664 1.3e-134 oppD3 P Belongs to the ABC transporter superfamily
EBFKHPNK_01665 1.1e-133 oppF3 E Belongs to the ABC transporter superfamily
EBFKHPNK_01666 6.6e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EBFKHPNK_01667 4.4e-185 S Amidohydrolase
EBFKHPNK_01668 4.2e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EBFKHPNK_01669 1e-179 ssuA M Sulfonate ABC transporter
EBFKHPNK_01670 1.2e-144 ssuC P ABC transporter (permease)
EBFKHPNK_01671 1.1e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
EBFKHPNK_01672 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBFKHPNK_01673 3.3e-80 ygaO
EBFKHPNK_01674 4.8e-23 K Transcriptional regulator
EBFKHPNK_01676 1.5e-112 yhzB S B3/4 domain
EBFKHPNK_01677 5.4e-225 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EBFKHPNK_01678 4.8e-176 yhbB S Putative amidase domain
EBFKHPNK_01679 1.3e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EBFKHPNK_01680 1e-108 yhbD K Protein of unknown function (DUF4004)
EBFKHPNK_01681 9.5e-63 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
EBFKHPNK_01682 2.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
EBFKHPNK_01684 0.0 prkA T Ser protein kinase
EBFKHPNK_01685 5.2e-215 yhbH S Belongs to the UPF0229 family
EBFKHPNK_01686 6e-74 yhbI K DNA-binding transcription factor activity
EBFKHPNK_01687 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
EBFKHPNK_01688 2.4e-284 yhcA EGP Major facilitator Superfamily
EBFKHPNK_01689 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
EBFKHPNK_01690 3.8e-55 yhcC
EBFKHPNK_01691 9.6e-53
EBFKHPNK_01692 5.6e-62 yhcF K Transcriptional regulator
EBFKHPNK_01693 1.4e-125 yhcG V ABC transporter, ATP-binding protein
EBFKHPNK_01694 1.5e-166 yhcH V ABC transporter, ATP-binding protein
EBFKHPNK_01695 4.8e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EBFKHPNK_01696 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
EBFKHPNK_01697 2.9e-148 metQ M Belongs to the nlpA lipoprotein family
EBFKHPNK_01698 5.4e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
EBFKHPNK_01699 7.1e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EBFKHPNK_01700 1.6e-55 yhcM
EBFKHPNK_01701 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EBFKHPNK_01702 2.4e-159 yhcP
EBFKHPNK_01703 2.9e-114 yhcQ M Spore coat protein
EBFKHPNK_01704 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
EBFKHPNK_01705 3.4e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
EBFKHPNK_01706 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EBFKHPNK_01707 1.3e-69 yhcU S Family of unknown function (DUF5365)
EBFKHPNK_01708 2.6e-68 yhcV S COG0517 FOG CBS domain
EBFKHPNK_01709 4.9e-125 yhcW 5.4.2.6 S hydrolase
EBFKHPNK_01710 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EBFKHPNK_01711 6.4e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EBFKHPNK_01712 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EBFKHPNK_01713 6.5e-148 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
EBFKHPNK_01714 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EBFKHPNK_01715 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EBFKHPNK_01716 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EBFKHPNK_01717 1.2e-22 yhcY 2.7.13.3 T Histidine kinase
EBFKHPNK_01718 2.8e-109 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EBFKHPNK_01719 8.8e-90 azr 1.7.1.6 S NADPH-dependent FMN reductase
EBFKHPNK_01720 1.2e-38 yhdB S YhdB-like protein
EBFKHPNK_01721 1.5e-52 yhdC S Protein of unknown function (DUF3889)
EBFKHPNK_01722 2.3e-217 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EBFKHPNK_01723 5.6e-74 nsrR K Transcriptional regulator
EBFKHPNK_01724 5.5e-254 ygxB M Conserved TM helix
EBFKHPNK_01725 1.2e-271 ycgB S Stage V sporulation protein R
EBFKHPNK_01726 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
EBFKHPNK_01727 4.4e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EBFKHPNK_01728 9e-164 citR K Transcriptional regulator
EBFKHPNK_01729 4.9e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
EBFKHPNK_01730 5.1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_01731 1.2e-250 yhdG E amino acid
EBFKHPNK_01732 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EBFKHPNK_01733 8.1e-45 yhdK S Sigma-M inhibitor protein
EBFKHPNK_01734 6.6e-201 yhdL S Sigma factor regulator N-terminal
EBFKHPNK_01735 9.4e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
EBFKHPNK_01736 1.3e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EBFKHPNK_01737 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EBFKHPNK_01738 4.3e-71 cueR K transcriptional
EBFKHPNK_01739 9.4e-225 yhdR 2.6.1.1 E Aminotransferase
EBFKHPNK_01740 7.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EBFKHPNK_01741 1.6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
EBFKHPNK_01742 8.5e-52 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBFKHPNK_01743 3.5e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBFKHPNK_01744 1.7e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EBFKHPNK_01746 1.6e-205 yhdY M Mechanosensitive ion channel
EBFKHPNK_01747 3.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EBFKHPNK_01748 1.2e-157 yheN G deacetylase
EBFKHPNK_01749 3.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EBFKHPNK_01750 4.6e-88 pksA K Transcriptional regulator
EBFKHPNK_01751 2.8e-94 ymcC S Membrane
EBFKHPNK_01752 1.8e-84 T universal stress protein
EBFKHPNK_01754 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
EBFKHPNK_01755 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
EBFKHPNK_01756 1.6e-111 yheG GM NAD(P)H-binding
EBFKHPNK_01758 1.3e-28 sspB S spore protein
EBFKHPNK_01759 1.7e-36 yheE S Family of unknown function (DUF5342)
EBFKHPNK_01760 5.1e-259 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
EBFKHPNK_01761 1.1e-214 yheC HJ YheC/D like ATP-grasp
EBFKHPNK_01762 4.2e-206 yheB S Belongs to the UPF0754 family
EBFKHPNK_01763 4.4e-53 yheA S Belongs to the UPF0342 family
EBFKHPNK_01764 1.7e-202 yhaZ L DNA alkylation repair enzyme
EBFKHPNK_01765 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
EBFKHPNK_01766 2.1e-293 hemZ H coproporphyrinogen III oxidase
EBFKHPNK_01767 3.7e-251 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
EBFKHPNK_01768 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
EBFKHPNK_01769 1.7e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
EBFKHPNK_01771 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
EBFKHPNK_01772 2.8e-14 S YhzD-like protein
EBFKHPNK_01773 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
EBFKHPNK_01774 2.3e-205 yhaP CP COG1668 ABC-type Na efflux pump, permease component
EBFKHPNK_01775 2.7e-235 yhaO L DNA repair exonuclease
EBFKHPNK_01776 0.0 yhaN L AAA domain
EBFKHPNK_01777 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
EBFKHPNK_01778 1.6e-32 yhaL S Sporulation protein YhaL
EBFKHPNK_01779 1.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EBFKHPNK_01780 7e-95 yhaK S Putative zincin peptidase
EBFKHPNK_01781 9.9e-55 yhaI S Protein of unknown function (DUF1878)
EBFKHPNK_01782 8.6e-113 hpr K Negative regulator of protease production and sporulation
EBFKHPNK_01783 2.4e-38 yhaH S YtxH-like protein
EBFKHPNK_01784 2e-17
EBFKHPNK_01785 3.8e-77 trpP S Tryptophan transporter TrpP
EBFKHPNK_01786 1.7e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBFKHPNK_01787 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EBFKHPNK_01788 1.1e-135 ecsA V transporter (ATP-binding protein)
EBFKHPNK_01789 8.5e-221 ecsB U ABC transporter
EBFKHPNK_01790 7.3e-124 ecsC S EcsC protein family
EBFKHPNK_01791 2.3e-223 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EBFKHPNK_01792 3.1e-243 yhfA C membrane
EBFKHPNK_01793 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EBFKHPNK_01794 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EBFKHPNK_01795 5.6e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EBFKHPNK_01796 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EBFKHPNK_01797 2.7e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EBFKHPNK_01798 1.2e-100 yhgD K Transcriptional regulator
EBFKHPNK_01799 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
EBFKHPNK_01800 2.8e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBFKHPNK_01802 2.5e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
EBFKHPNK_01803 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EBFKHPNK_01804 7.9e-11 yhfH S YhfH-like protein
EBFKHPNK_01805 1.5e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EBFKHPNK_01806 3.5e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
EBFKHPNK_01807 2.6e-112 yhfK GM NmrA-like family
EBFKHPNK_01808 5.4e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EBFKHPNK_01809 8.7e-66 yhfM
EBFKHPNK_01810 6e-238 yhfN 3.4.24.84 O Peptidase M48
EBFKHPNK_01811 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
EBFKHPNK_01812 2.8e-157 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EBFKHPNK_01813 1.7e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
EBFKHPNK_01814 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
EBFKHPNK_01815 3.5e-282 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EBFKHPNK_01816 9.3e-90 bioY S BioY family
EBFKHPNK_01817 9.1e-197 hemAT NT chemotaxis protein
EBFKHPNK_01818 2.8e-298 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
EBFKHPNK_01819 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_01820 1.3e-32 yhzC S IDEAL
EBFKHPNK_01821 9.3e-109 comK K Competence transcription factor
EBFKHPNK_01822 3.9e-68 frataxin S Domain of unknown function (DU1801)
EBFKHPNK_01823 1.6e-66 frataxin S Domain of unknown function (DU1801)
EBFKHPNK_01824 1.2e-91 mepB S MepB protein
EBFKHPNK_01825 3e-125 yrpD S Domain of unknown function, YrpD
EBFKHPNK_01826 1.6e-42 yhjA S Excalibur calcium-binding domain
EBFKHPNK_01827 3.3e-47 S Belongs to the UPF0145 family
EBFKHPNK_01828 9.5e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBFKHPNK_01829 1.4e-27 yhjC S Protein of unknown function (DUF3311)
EBFKHPNK_01830 1.7e-60 yhjD
EBFKHPNK_01831 1.4e-110 yhjE S SNARE associated Golgi protein
EBFKHPNK_01832 1.6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
EBFKHPNK_01833 4.6e-277 yhjG CH FAD binding domain
EBFKHPNK_01834 2.9e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
EBFKHPNK_01835 4.3e-182 abrB S membrane
EBFKHPNK_01836 1.1e-209 blt EGP Major facilitator Superfamily
EBFKHPNK_01837 4.5e-109 K QacR-like protein, C-terminal region
EBFKHPNK_01838 4.8e-93 yhjR S Rubrerythrin
EBFKHPNK_01839 1.1e-74 ydfS S Protein of unknown function (DUF421)
EBFKHPNK_01840 5.7e-41 ydfS S Protein of unknown function (DUF421)
EBFKHPNK_01841 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
EBFKHPNK_01842 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EBFKHPNK_01843 3.9e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EBFKHPNK_01844 0.0 sbcC L COG0419 ATPase involved in DNA repair
EBFKHPNK_01845 5.5e-49 yisB V COG1403 Restriction endonuclease
EBFKHPNK_01846 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
EBFKHPNK_01847 1.2e-62 gerPE S Spore germination protein GerPE
EBFKHPNK_01848 3.1e-23 gerPD S Spore germination protein
EBFKHPNK_01849 9.1e-62 gerPC S Spore germination protein
EBFKHPNK_01850 6.2e-35 gerPB S cell differentiation
EBFKHPNK_01851 8.4e-34 gerPA S Spore germination protein
EBFKHPNK_01852 5e-07 yisI S Spo0E like sporulation regulatory protein
EBFKHPNK_01853 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EBFKHPNK_01854 3.2e-59 yisL S UPF0344 protein
EBFKHPNK_01855 2e-97 yisN S Protein of unknown function (DUF2777)
EBFKHPNK_01856 0.0 asnO 6.3.5.4 E Asparagine synthase
EBFKHPNK_01857 1.5e-132 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
EBFKHPNK_01858 1.9e-245 yisQ V Mate efflux family protein
EBFKHPNK_01859 8.6e-159 yisR K Transcriptional regulator
EBFKHPNK_01860 3.7e-90 yisT S DinB family
EBFKHPNK_01861 3.5e-74 argO S Lysine exporter protein LysE YggA
EBFKHPNK_01862 2.9e-191 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EBFKHPNK_01863 1.3e-71 mcbG S Pentapeptide repeats (9 copies)
EBFKHPNK_01864 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
EBFKHPNK_01865 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EBFKHPNK_01866 6.6e-55 yajQ S Belongs to the UPF0234 family
EBFKHPNK_01867 1.8e-161 cvfB S protein conserved in bacteria
EBFKHPNK_01868 3.7e-174 yufN S ABC transporter substrate-binding protein PnrA-like
EBFKHPNK_01869 5.9e-233 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
EBFKHPNK_01870 3.2e-239 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
EBFKHPNK_01872 3.2e-158 yitS S protein conserved in bacteria
EBFKHPNK_01873 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
EBFKHPNK_01874 1.9e-80 ipi S Intracellular proteinase inhibitor
EBFKHPNK_01875 4.4e-26 S Protein of unknown function (DUF3813)
EBFKHPNK_01876 3.5e-07
EBFKHPNK_01877 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EBFKHPNK_01878 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EBFKHPNK_01879 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
EBFKHPNK_01880 4.5e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EBFKHPNK_01881 9.5e-272 yitY C D-arabinono-1,4-lactone oxidase
EBFKHPNK_01882 4.1e-90 norB G Major Facilitator Superfamily
EBFKHPNK_01883 5.6e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EBFKHPNK_01884 7.2e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EBFKHPNK_01885 3.7e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
EBFKHPNK_01886 5.8e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EBFKHPNK_01887 8.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EBFKHPNK_01888 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
EBFKHPNK_01889 1.6e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBFKHPNK_01890 1.2e-27 yjzC S YjzC-like protein
EBFKHPNK_01891 3.3e-23 yjzD S Protein of unknown function (DUF2929)
EBFKHPNK_01892 4.6e-137 yjaU I carboxylic ester hydrolase activity
EBFKHPNK_01893 8.8e-104 yjaV
EBFKHPNK_01894 5.5e-166 med S Transcriptional activator protein med
EBFKHPNK_01895 1.1e-26 comZ S ComZ
EBFKHPNK_01896 5.9e-32 yjzB
EBFKHPNK_01897 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBFKHPNK_01898 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EBFKHPNK_01899 5.6e-149 yjaZ O Zn-dependent protease
EBFKHPNK_01900 1.7e-182 appD P Belongs to the ABC transporter superfamily
EBFKHPNK_01901 2.2e-187 appF E Belongs to the ABC transporter superfamily
EBFKHPNK_01902 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
EBFKHPNK_01903 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBFKHPNK_01904 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBFKHPNK_01905 5.5e-146 yjbA S Belongs to the UPF0736 family
EBFKHPNK_01906 1.8e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EBFKHPNK_01907 0.0 oppA E ABC transporter substrate-binding protein
EBFKHPNK_01908 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBFKHPNK_01909 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBFKHPNK_01910 4.6e-202 oppD P Belongs to the ABC transporter superfamily
EBFKHPNK_01911 2.5e-172 oppF E Belongs to the ABC transporter superfamily
EBFKHPNK_01912 1.4e-231 S Putative glycosyl hydrolase domain
EBFKHPNK_01913 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EBFKHPNK_01914 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EBFKHPNK_01915 3.6e-109 yjbE P Integral membrane protein TerC family
EBFKHPNK_01916 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EBFKHPNK_01917 3.6e-221 yjbF S Competence protein
EBFKHPNK_01918 0.0 pepF E oligoendopeptidase F
EBFKHPNK_01919 5.8e-19
EBFKHPNK_01920 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EBFKHPNK_01921 4.8e-72 yjbI S Bacterial-like globin
EBFKHPNK_01922 2.1e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EBFKHPNK_01923 3.5e-100 yjbK S protein conserved in bacteria
EBFKHPNK_01924 1.6e-61 yjbL S Belongs to the UPF0738 family
EBFKHPNK_01925 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
EBFKHPNK_01926 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBFKHPNK_01927 4.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EBFKHPNK_01928 3e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EBFKHPNK_01929 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EBFKHPNK_01930 2e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EBFKHPNK_01931 4.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
EBFKHPNK_01932 4.1e-214 thiO 1.4.3.19 E Glycine oxidase
EBFKHPNK_01933 1.4e-30 thiS H Thiamine biosynthesis
EBFKHPNK_01934 3.8e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EBFKHPNK_01935 7.1e-189 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EBFKHPNK_01936 2.9e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EBFKHPNK_01937 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EBFKHPNK_01938 1.1e-85 yjbX S Spore coat protein
EBFKHPNK_01939 2.6e-79 cotZ S Spore coat protein
EBFKHPNK_01940 8.1e-90 cotY S Spore coat protein Z
EBFKHPNK_01941 4.2e-73 cotX S Spore Coat Protein X and V domain
EBFKHPNK_01942 2.5e-23 cotW
EBFKHPNK_01943 1.4e-52 cotV S Spore Coat Protein X and V domain
EBFKHPNK_01944 5.6e-56 yjcA S Protein of unknown function (DUF1360)
EBFKHPNK_01948 3.8e-38 spoVIF S Stage VI sporulation protein F
EBFKHPNK_01949 0.0 yjcD 3.6.4.12 L DNA helicase
EBFKHPNK_01950 2.1e-36
EBFKHPNK_01951 3.3e-129 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EBFKHPNK_01952 1.5e-124 S ABC-2 type transporter
EBFKHPNK_01953 3.1e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
EBFKHPNK_01954 9.4e-36 K SpoVT / AbrB like domain
EBFKHPNK_01956 1.1e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EBFKHPNK_01957 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
EBFKHPNK_01958 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
EBFKHPNK_01959 1.3e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EBFKHPNK_01960 7.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EBFKHPNK_01966 5.6e-23 M1-820 Q Collagen triple helix repeat (20 copies)
EBFKHPNK_01967 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
EBFKHPNK_01968 6.9e-271 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EBFKHPNK_01969 4.7e-120 citT T response regulator
EBFKHPNK_01970 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
EBFKHPNK_01971 1.4e-226 citM C Citrate transporter
EBFKHPNK_01972 4.3e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
EBFKHPNK_01973 5.5e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EBFKHPNK_01974 1.7e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EBFKHPNK_01975 4.4e-123 yflK S protein conserved in bacteria
EBFKHPNK_01976 1.5e-14 yflJ S Protein of unknown function (DUF2639)
EBFKHPNK_01977 7e-19 yflI
EBFKHPNK_01978 3.4e-49 yflH S Protein of unknown function (DUF3243)
EBFKHPNK_01979 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
EBFKHPNK_01980 1.6e-244 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EBFKHPNK_01981 3.1e-72 yfmQ S Uncharacterised protein from bacillus cereus group
EBFKHPNK_01982 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EBFKHPNK_01983 7.8e-64 yhdN S Domain of unknown function (DUF1992)
EBFKHPNK_01984 9.8e-79 cotP O Belongs to the small heat shock protein (HSP20) family
EBFKHPNK_01985 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
EBFKHPNK_01986 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
EBFKHPNK_01987 1e-238 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EBFKHPNK_01988 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EBFKHPNK_01989 1.7e-128 treR K transcriptional
EBFKHPNK_01990 1.2e-123 yfkO C nitroreductase
EBFKHPNK_01991 4.2e-125 yibF S YibE/F-like protein
EBFKHPNK_01992 8.3e-202 yibE S YibE/F-like protein
EBFKHPNK_01993 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
EBFKHPNK_01994 6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
EBFKHPNK_01995 1.3e-185 K helix_turn _helix lactose operon repressor
EBFKHPNK_01996 5.3e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EBFKHPNK_01997 3.4e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EBFKHPNK_01998 4.3e-193 ydiM EGP Major facilitator Superfamily
EBFKHPNK_01999 7.9e-29 yfkK S Belongs to the UPF0435 family
EBFKHPNK_02000 1.2e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBFKHPNK_02001 8.5e-51 yfkI S gas vesicle protein
EBFKHPNK_02002 6.8e-145 yihY S Belongs to the UPF0761 family
EBFKHPNK_02003 2.5e-07
EBFKHPNK_02004 5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
EBFKHPNK_02005 1.3e-185 cax P COG0387 Ca2 H antiporter
EBFKHPNK_02006 1.9e-144 yfkD S YfkD-like protein
EBFKHPNK_02007 3.3e-147 yfkC M Mechanosensitive ion channel
EBFKHPNK_02008 3e-220 yfkA S YfkB-like domain
EBFKHPNK_02009 4.9e-27 yfjT
EBFKHPNK_02010 9e-155 pdaA G deacetylase
EBFKHPNK_02011 8.5e-151 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EBFKHPNK_02012 1.4e-33
EBFKHPNK_02013 1.7e-184 corA P Mediates influx of magnesium ions
EBFKHPNK_02014 1.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EBFKHPNK_02015 4.8e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EBFKHPNK_02017 2.5e-60 M1-386
EBFKHPNK_02018 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBFKHPNK_02019 2.1e-90 yfjM S Psort location Cytoplasmic, score
EBFKHPNK_02020 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EBFKHPNK_02021 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EBFKHPNK_02022 4.4e-214 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EBFKHPNK_02023 9.5e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EBFKHPNK_02024 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
EBFKHPNK_02025 4.2e-15 sspH S Belongs to the SspH family
EBFKHPNK_02026 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EBFKHPNK_02027 3.9e-139 glvR F Helix-turn-helix domain, rpiR family
EBFKHPNK_02028 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EBFKHPNK_02029 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
EBFKHPNK_02030 0.0 yfiB3 V ABC transporter
EBFKHPNK_02031 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
EBFKHPNK_02032 7e-63 mhqP S DoxX
EBFKHPNK_02033 4.5e-160 yfiE 1.13.11.2 S glyoxalase
EBFKHPNK_02034 4.2e-167 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EBFKHPNK_02035 1.7e-96 padR K transcriptional
EBFKHPNK_02036 1.2e-111 1.6.5.2 S NADPH-dependent FMN reductase
EBFKHPNK_02037 2.9e-180 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EBFKHPNK_02039 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
EBFKHPNK_02040 1.5e-45 yrdF K ribonuclease inhibitor
EBFKHPNK_02041 1.4e-98 yfiT S Belongs to the metal hydrolase YfiT family
EBFKHPNK_02042 8.6e-290 yfiU EGP Major facilitator Superfamily
EBFKHPNK_02043 5.6e-83 yfiV K transcriptional
EBFKHPNK_02044 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBFKHPNK_02045 3.3e-166 yfhB 5.3.3.17 S PhzF family
EBFKHPNK_02046 1.7e-105 yfhC C nitroreductase
EBFKHPNK_02047 2.1e-25 yfhD S YfhD-like protein
EBFKHPNK_02049 1.5e-166 yfhF S nucleoside-diphosphate sugar epimerase
EBFKHPNK_02050 5.1e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
EBFKHPNK_02051 8.8e-53 yfhH S Protein of unknown function (DUF1811)
EBFKHPNK_02052 4.5e-206 yfhI EGP Major facilitator Superfamily
EBFKHPNK_02054 6.9e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
EBFKHPNK_02055 2.2e-44 yfhJ S WVELL protein
EBFKHPNK_02056 1.6e-94 batE T Bacterial SH3 domain homologues
EBFKHPNK_02057 2.6e-34 yfhL S SdpI/YhfL protein family
EBFKHPNK_02058 1.3e-170 yfhM S Alpha/beta hydrolase family
EBFKHPNK_02059 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EBFKHPNK_02060 0.0 yfhO S Bacterial membrane protein YfhO
EBFKHPNK_02061 3e-184 yfhP S membrane-bound metal-dependent
EBFKHPNK_02062 4.7e-210 mutY L A G-specific
EBFKHPNK_02063 8.2e-37 yfhS
EBFKHPNK_02064 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_02066 1.5e-37 ygaB S YgaB-like protein
EBFKHPNK_02067 2.2e-104 ygaC J Belongs to the UPF0374 family
EBFKHPNK_02068 4.2e-306 ygaD V ABC transporter
EBFKHPNK_02069 2.1e-178 ygaE S Membrane
EBFKHPNK_02070 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EBFKHPNK_02071 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
EBFKHPNK_02072 1.8e-80 perR P Belongs to the Fur family
EBFKHPNK_02073 1.5e-56 ygzB S UPF0295 protein
EBFKHPNK_02074 8.2e-165 ygxA S Nucleotidyltransferase-like
EBFKHPNK_02076 7.9e-28 Q PFAM Collagen triple helix
EBFKHPNK_02077 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
EBFKHPNK_02078 5.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
EBFKHPNK_02079 1.3e-57 yflT S Heat induced stress protein YflT
EBFKHPNK_02080 9.9e-25 S Protein of unknown function (DUF3212)
EBFKHPNK_02081 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
EBFKHPNK_02082 6.4e-65 yfmK 2.3.1.128 K acetyltransferase
EBFKHPNK_02083 4.2e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
EBFKHPNK_02084 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EBFKHPNK_02085 2.1e-208 yfmO EGP Major facilitator Superfamily
EBFKHPNK_02086 1.8e-69 yfmP K transcriptional
EBFKHPNK_02087 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EBFKHPNK_02088 7.2e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EBFKHPNK_02089 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
EBFKHPNK_02090 9.8e-115 yfmS NT chemotaxis protein
EBFKHPNK_02091 5.9e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EBFKHPNK_02092 2.3e-246 yfnA E amino acid
EBFKHPNK_02093 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
EBFKHPNK_02094 2.4e-186 yfnD M Nucleotide-diphospho-sugar transferase
EBFKHPNK_02095 5.1e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
EBFKHPNK_02096 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
EBFKHPNK_02097 2.4e-172 yfnG 4.2.1.45 M dehydratase
EBFKHPNK_02098 2.3e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
EBFKHPNK_02099 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EBFKHPNK_02101 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EBFKHPNK_02102 7.5e-197 yetN S Protein of unknown function (DUF3900)
EBFKHPNK_02103 1.9e-206 yetM CH FAD binding domain
EBFKHPNK_02104 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
EBFKHPNK_02106 1.1e-105 yetJ S Belongs to the BI1 family
EBFKHPNK_02107 1.2e-54 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
EBFKHPNK_02108 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
EBFKHPNK_02109 7.5e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EBFKHPNK_02110 8.3e-63 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EBFKHPNK_02111 2.2e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EBFKHPNK_02112 1.3e-120 yetF S membrane
EBFKHPNK_02114 7.5e-97 yesJ K Acetyltransferase (GNAT) family
EBFKHPNK_02115 8.9e-104 cotJC P Spore Coat
EBFKHPNK_02116 3.3e-45 cotJB S CotJB protein
EBFKHPNK_02117 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
EBFKHPNK_02119 9.4e-127 yeeN K transcriptional regulatory protein
EBFKHPNK_02120 6e-19
EBFKHPNK_02122 5.6e-183 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBFKHPNK_02123 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
EBFKHPNK_02124 8.4e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
EBFKHPNK_02125 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EBFKHPNK_02126 8.6e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBFKHPNK_02127 0.0 ydiF S ABC transporter
EBFKHPNK_02128 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EBFKHPNK_02129 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EBFKHPNK_02130 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EBFKHPNK_02131 9.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBFKHPNK_02132 1.7e-27 ydiK S Domain of unknown function (DUF4305)
EBFKHPNK_02133 1.3e-126 ydiL S CAAX protease self-immunity
EBFKHPNK_02134 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBFKHPNK_02135 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EBFKHPNK_02136 1.5e-24 S Protein of unknown function (DUF4064)
EBFKHPNK_02137 0.0 K NB-ARC domain
EBFKHPNK_02138 3.2e-200 gutB 1.1.1.14 E Dehydrogenase
EBFKHPNK_02139 2.4e-248 gutA G MFS/sugar transport protein
EBFKHPNK_02140 1.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
EBFKHPNK_02141 2.3e-29 yjdJ S Domain of unknown function (DUF4306)
EBFKHPNK_02142 1.8e-114 pspA KT Phage shock protein A
EBFKHPNK_02143 6.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBFKHPNK_02144 7.4e-122 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
EBFKHPNK_02145 3.9e-155 ydjI S virion core protein (lumpy skin disease virus)
EBFKHPNK_02146 0.0 yrhL I Acyltransferase family
EBFKHPNK_02147 8.3e-146 rsiV S Protein of unknown function (DUF3298)
EBFKHPNK_02148 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EBFKHPNK_02149 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
EBFKHPNK_02150 4.2e-62 ydjM M Lytic transglycolase
EBFKHPNK_02151 4.7e-135 ydjN U Involved in the tonB-independent uptake of proteins
EBFKHPNK_02153 7.2e-35 ydjO S Cold-inducible protein YdjO
EBFKHPNK_02154 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
EBFKHPNK_02155 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
EBFKHPNK_02156 7.1e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EBFKHPNK_02157 1.7e-176 yeaC S COG0714 MoxR-like ATPases
EBFKHPNK_02158 1.2e-214 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EBFKHPNK_02159 0.0 yebA E COG1305 Transglutaminase-like enzymes
EBFKHPNK_02160 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EBFKHPNK_02161 3.1e-128 K Acetyltransferase (GNAT) domain
EBFKHPNK_02162 1.3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EBFKHPNK_02163 3.7e-247 S Domain of unknown function (DUF4179)
EBFKHPNK_02164 6.2e-209 pbuG S permease
EBFKHPNK_02165 3.3e-125 yebC M Membrane
EBFKHPNK_02167 2e-92 yebE S UPF0316 protein
EBFKHPNK_02168 6.1e-28 yebG S NETI protein
EBFKHPNK_02169 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EBFKHPNK_02170 1e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EBFKHPNK_02171 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EBFKHPNK_02172 1.8e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EBFKHPNK_02173 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBFKHPNK_02174 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBFKHPNK_02175 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBFKHPNK_02176 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EBFKHPNK_02177 2.7e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EBFKHPNK_02178 2.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBFKHPNK_02179 3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EBFKHPNK_02180 8.2e-235 purD 6.3.4.13 F Belongs to the GARS family
EBFKHPNK_02181 2e-25 S Protein of unknown function (DUF2892)
EBFKHPNK_02182 0.0 yerA 3.5.4.2 F adenine deaminase
EBFKHPNK_02183 1.4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
EBFKHPNK_02184 2.4e-50 yerC S protein conserved in bacteria
EBFKHPNK_02185 1.4e-300 yerD 1.4.7.1 E Belongs to the glutamate synthase family
EBFKHPNK_02186 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EBFKHPNK_02187 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EBFKHPNK_02188 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBFKHPNK_02189 2.3e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
EBFKHPNK_02190 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
EBFKHPNK_02191 1.3e-120 sapB S MgtC SapB transporter
EBFKHPNK_02192 1.6e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBFKHPNK_02193 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EBFKHPNK_02194 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EBFKHPNK_02195 4.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EBFKHPNK_02196 1.1e-153 yerO K Transcriptional regulator
EBFKHPNK_02197 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBFKHPNK_02198 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EBFKHPNK_02199 2.1e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EBFKHPNK_02200 7.7e-21
EBFKHPNK_02201 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
EBFKHPNK_02202 5.7e-21 cylB V ABC-2 type transporter
EBFKHPNK_02203 2.3e-103 cylB V ABC-2 type transporter
EBFKHPNK_02204 1.5e-25 S Protein of unknown function, DUF600
EBFKHPNK_02205 1.5e-77 S Protein of unknown function, DUF600
EBFKHPNK_02206 2.5e-56 S Protein of unknown function, DUF600
EBFKHPNK_02207 1.6e-53 S Protein of unknown function, DUF600
EBFKHPNK_02208 1.3e-214 yobL L nucleic acid phosphodiester bond hydrolysis
EBFKHPNK_02209 3.4e-39 S COG NOG14552 non supervised orthologous group
EBFKHPNK_02210 1.3e-59 LO Belongs to the peptidase S16 family
EBFKHPNK_02212 5.4e-71 S response regulator aspartate phosphatase
EBFKHPNK_02213 9e-97 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EBFKHPNK_02214 3.3e-78 K Transcriptional regulator
EBFKHPNK_02216 9.2e-11 S Doxx family
EBFKHPNK_02217 3.2e-08
EBFKHPNK_02222 8.8e-119 S Histidine kinase
EBFKHPNK_02223 8.1e-42 S Histidine kinase
EBFKHPNK_02225 3.9e-10
EBFKHPNK_02227 3.7e-78
EBFKHPNK_02228 8.2e-42
EBFKHPNK_02229 2.1e-39
EBFKHPNK_02230 2e-225 mntH P H( )-stimulated, divalent metal cation uptake system
EBFKHPNK_02232 2.5e-22 ydaT
EBFKHPNK_02233 1.6e-70 yvaD S Family of unknown function (DUF5360)
EBFKHPNK_02234 1.2e-53 yvaE P Small Multidrug Resistance protein
EBFKHPNK_02235 4.9e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
EBFKHPNK_02237 8.2e-63 ydbB G Cupin domain
EBFKHPNK_02238 5.9e-61 ydbC S Domain of unknown function (DUF4937
EBFKHPNK_02239 6.5e-156 ydbD P Catalase
EBFKHPNK_02240 7.1e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EBFKHPNK_02241 1.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EBFKHPNK_02242 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
EBFKHPNK_02243 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EBFKHPNK_02244 3.6e-159 ydbI S AI-2E family transporter
EBFKHPNK_02245 2.5e-172 ydbJ V ABC transporter, ATP-binding protein
EBFKHPNK_02246 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EBFKHPNK_02247 6.1e-52 ydbL
EBFKHPNK_02248 3.5e-205 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
EBFKHPNK_02249 1.5e-10 S Fur-regulated basic protein B
EBFKHPNK_02250 1.3e-08 S Fur-regulated basic protein A
EBFKHPNK_02251 8.1e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EBFKHPNK_02252 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EBFKHPNK_02253 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EBFKHPNK_02254 3.1e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EBFKHPNK_02255 2.9e-247 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EBFKHPNK_02256 2.1e-82 ydbS S Bacterial PH domain
EBFKHPNK_02257 1.7e-263 ydbT S Membrane
EBFKHPNK_02258 3.1e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
EBFKHPNK_02259 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EBFKHPNK_02260 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
EBFKHPNK_02261 5.3e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EBFKHPNK_02262 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EBFKHPNK_02263 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
EBFKHPNK_02264 5.7e-144 rsbR T Positive regulator of sigma-B
EBFKHPNK_02265 1.8e-57 rsbS T antagonist
EBFKHPNK_02266 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EBFKHPNK_02267 1.7e-187 rsbU 3.1.3.3 KT phosphatase
EBFKHPNK_02268 4.1e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
EBFKHPNK_02269 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EBFKHPNK_02270 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBFKHPNK_02271 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
EBFKHPNK_02272 0.0 yhgF K COG2183 Transcriptional accessory protein
EBFKHPNK_02273 1.7e-14
EBFKHPNK_02274 3.3e-58 ydcK S Belongs to the SprT family
EBFKHPNK_02282 1.1e-227 proP EGP Transporter
EBFKHPNK_02283 9.5e-83 S Domain of unknown function with cystatin-like fold (DUF4467)
EBFKHPNK_02284 1.2e-73 maoC I N-terminal half of MaoC dehydratase
EBFKHPNK_02285 3.2e-64 yyaQ S YjbR
EBFKHPNK_02286 1.3e-73 ywnA K Transcriptional regulator
EBFKHPNK_02287 9.9e-112 ywnB S NAD(P)H-binding
EBFKHPNK_02288 1.4e-30 cspL K Cold shock
EBFKHPNK_02289 5.2e-78 carD K Transcription factor
EBFKHPNK_02290 4.6e-39 yrkD S protein conserved in bacteria
EBFKHPNK_02291 1.6e-82 yrkE O DsrE/DsrF/DrsH-like family
EBFKHPNK_02292 2.1e-58 P Rhodanese Homology Domain
EBFKHPNK_02293 4.1e-93 yrkF OP Belongs to the sulfur carrier protein TusA family
EBFKHPNK_02294 2.1e-197 yrkH P Rhodanese Homology Domain
EBFKHPNK_02295 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
EBFKHPNK_02296 2.3e-118 yrkJ S membrane transporter protein
EBFKHPNK_02297 1.9e-121 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EBFKHPNK_02298 3.8e-99 S Protein of unknown function (DUF2812)
EBFKHPNK_02299 4.9e-51 K Transcriptional regulator PadR-like family
EBFKHPNK_02300 5.2e-181 S Patatin-like phospholipase
EBFKHPNK_02301 1.2e-77 S DinB superfamily
EBFKHPNK_02302 2.2e-63 G Cupin domain
EBFKHPNK_02305 1.3e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
EBFKHPNK_02306 6.3e-38 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EBFKHPNK_02307 2.3e-165 czcD P COG1230 Co Zn Cd efflux system component
EBFKHPNK_02308 5.4e-200 trkA P Oxidoreductase
EBFKHPNK_02310 1e-98 yrkC G Cupin domain
EBFKHPNK_02311 1.1e-84 ykkA S Protein of unknown function (DUF664)
EBFKHPNK_02312 1.4e-146 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
EBFKHPNK_02314 2.7e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
EBFKHPNK_02315 3.5e-56 ydeH
EBFKHPNK_02316 6.4e-84 F nucleoside 2-deoxyribosyltransferase
EBFKHPNK_02317 1.1e-194 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EBFKHPNK_02318 2.3e-147 Q ubiE/COQ5 methyltransferase family
EBFKHPNK_02319 3.2e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EBFKHPNK_02320 6.8e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EBFKHPNK_02321 1.8e-165 S Sodium Bile acid symporter family
EBFKHPNK_02322 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
EBFKHPNK_02323 3.6e-67 yraB K helix_turn_helix, mercury resistance
EBFKHPNK_02324 1.1e-226 mleN_2 C antiporter
EBFKHPNK_02325 4.7e-260 K helix_turn_helix gluconate operon transcriptional repressor
EBFKHPNK_02326 1.2e-114 paiB K Transcriptional regulator
EBFKHPNK_02328 2.2e-173 ydeR EGP Major facilitator Superfamily
EBFKHPNK_02329 2.2e-102 ydeS K Transcriptional regulator
EBFKHPNK_02330 9.1e-156 ydeK EG -transporter
EBFKHPNK_02331 1.5e-266 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EBFKHPNK_02332 4e-47 yraD M Spore coat protein
EBFKHPNK_02333 1.2e-23 yraE
EBFKHPNK_02334 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EBFKHPNK_02335 8.4e-63 yraF M Spore coat protein
EBFKHPNK_02336 1.7e-35 yraG
EBFKHPNK_02338 1.3e-216 ydfH 2.7.13.3 T Histidine kinase
EBFKHPNK_02339 2.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EBFKHPNK_02340 0.0 ydfJ S drug exporters of the RND superfamily
EBFKHPNK_02341 1.2e-132 puuD S Peptidase C26
EBFKHPNK_02343 1e-298 expZ S ABC transporter
EBFKHPNK_02344 2.1e-99 ynaD J Acetyltransferase (GNAT) domain
EBFKHPNK_02345 1.4e-148 S Uncharacterized protein conserved in bacteria (DUF2179)
EBFKHPNK_02346 3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EBFKHPNK_02347 1.8e-210 tcaB EGP Major facilitator Superfamily
EBFKHPNK_02348 4.4e-225 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EBFKHPNK_02349 1.3e-156 K Helix-turn-helix XRE-family like proteins
EBFKHPNK_02350 3.8e-123 ydhB S membrane transporter protein
EBFKHPNK_02351 3.8e-81 bltD 2.3.1.57 K FR47-like protein
EBFKHPNK_02352 5.6e-12 bltR K helix_turn_helix, mercury resistance
EBFKHPNK_02353 6e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
EBFKHPNK_02354 2e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
EBFKHPNK_02355 4.7e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
EBFKHPNK_02356 4e-119 ydhC K FCD
EBFKHPNK_02357 8.3e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EBFKHPNK_02360 3.4e-263 pbpE V Beta-lactamase
EBFKHPNK_02362 1.2e-97 ydhK M Protein of unknown function (DUF1541)
EBFKHPNK_02363 1.2e-195 pbuE EGP Major facilitator Superfamily
EBFKHPNK_02364 1.3e-133 ydhQ K UTRA
EBFKHPNK_02365 5.3e-119 K FCD
EBFKHPNK_02366 7.4e-217 yeaN P COG2807 Cyanate permease
EBFKHPNK_02367 2.6e-49 sugE P Small Multidrug Resistance protein
EBFKHPNK_02368 2.3e-51 ykkC P Small Multidrug Resistance protein
EBFKHPNK_02369 5.3e-104 yvdT K Transcriptional regulator
EBFKHPNK_02370 3.5e-296 yveA E amino acid
EBFKHPNK_02371 3.5e-165 ydhU P Catalase
EBFKHPNK_02372 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
EBFKHPNK_02373 1.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
EBFKHPNK_02374 1.1e-251 iolT EGP Major facilitator Superfamily
EBFKHPNK_02377 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EBFKHPNK_02378 2.2e-18 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EBFKHPNK_02379 0.0 ydaO E amino acid
EBFKHPNK_02380 0.0 ydaN S Bacterial cellulose synthase subunit
EBFKHPNK_02381 3.2e-231 ydaM M Glycosyl transferase family group 2
EBFKHPNK_02382 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
EBFKHPNK_02383 6.7e-148 ydaK T Diguanylate cyclase, GGDEF domain
EBFKHPNK_02384 1.6e-202 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
EBFKHPNK_02385 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBFKHPNK_02386 1.5e-74 lrpC K Transcriptional regulator
EBFKHPNK_02387 2.7e-48 ydzA EGP Major facilitator Superfamily
EBFKHPNK_02388 6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EBFKHPNK_02389 1.4e-77 ydaG 1.4.3.5 S general stress protein
EBFKHPNK_02390 7.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EBFKHPNK_02391 1.1e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
EBFKHPNK_02392 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_02393 5.5e-286 ydaB IQ acyl-CoA ligase
EBFKHPNK_02394 0.0 mtlR K transcriptional regulator, MtlR
EBFKHPNK_02395 1.3e-173 ydhF S Oxidoreductase
EBFKHPNK_02396 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
EBFKHPNK_02397 9.5e-55 yczJ S biosynthesis
EBFKHPNK_02399 1e-116 ycsK E anatomical structure formation involved in morphogenesis
EBFKHPNK_02400 3.4e-130 kipR K Transcriptional regulator
EBFKHPNK_02401 2.7e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
EBFKHPNK_02402 1.2e-137 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
EBFKHPNK_02403 3.5e-151 ycsI S Belongs to the D-glutamate cyclase family
EBFKHPNK_02404 3e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
EBFKHPNK_02405 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
EBFKHPNK_02406 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EBFKHPNK_02408 7.9e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
EBFKHPNK_02409 4.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
EBFKHPNK_02410 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EBFKHPNK_02411 4e-222 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
EBFKHPNK_02412 1.6e-55
EBFKHPNK_02413 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
EBFKHPNK_02414 1.6e-299 ycnJ P protein, homolog of Cu resistance protein CopC
EBFKHPNK_02415 3.5e-98 ycnI S protein conserved in bacteria
EBFKHPNK_02416 1.9e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_02417 3.6e-149 glcU U Glucose uptake
EBFKHPNK_02418 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EBFKHPNK_02419 1.6e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EBFKHPNK_02420 5.5e-264 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EBFKHPNK_02421 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
EBFKHPNK_02422 1e-44 ycnE S Monooxygenase
EBFKHPNK_02423 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
EBFKHPNK_02424 2.1e-152 ycnC K Transcriptional regulator
EBFKHPNK_02425 3.9e-249 ycnB EGP Major facilitator Superfamily
EBFKHPNK_02426 9.3e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
EBFKHPNK_02427 2e-135 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
EBFKHPNK_02428 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_02429 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_02430 5.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
EBFKHPNK_02432 1.9e-81 S aspartate phosphatase
EBFKHPNK_02433 2.3e-262 T PhoQ Sensor
EBFKHPNK_02434 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_02435 2.5e-235 yclI V ABC transporter (permease) YclI
EBFKHPNK_02436 1.4e-119 yclH P ABC transporter
EBFKHPNK_02437 7.1e-253 yxeQ S MmgE/PrpD family
EBFKHPNK_02438 6.8e-220 yxeP 3.5.1.47 E hydrolase activity
EBFKHPNK_02439 1e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
EBFKHPNK_02440 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
EBFKHPNK_02441 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
EBFKHPNK_02442 6.7e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EBFKHPNK_02443 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBFKHPNK_02444 3.9e-196 gerKB F Spore germination protein
EBFKHPNK_02445 5.5e-236 gerKC S spore germination
EBFKHPNK_02446 2.3e-285 gerKA EG Spore germination protein
EBFKHPNK_02448 9.5e-282 yclG M Pectate lyase superfamily protein
EBFKHPNK_02449 3.2e-270 dtpT E amino acid peptide transporter
EBFKHPNK_02450 5.2e-78 yclD
EBFKHPNK_02451 2e-38 bsdD 4.1.1.61 S response to toxic substance
EBFKHPNK_02452 1.4e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EBFKHPNK_02453 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EBFKHPNK_02454 1.1e-158 bsdA K LysR substrate binding domain
EBFKHPNK_02455 1.4e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EBFKHPNK_02456 2.1e-118 tcyB P COG0765 ABC-type amino acid transport system, permease component
EBFKHPNK_02457 1.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EBFKHPNK_02458 1.3e-111 yczE S membrane
EBFKHPNK_02459 1e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
EBFKHPNK_02460 3.6e-249 bamJ E Aminotransferase class I and II
EBFKHPNK_02461 1.3e-139 srfAD Q thioesterase
EBFKHPNK_02462 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
EBFKHPNK_02463 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_02464 3.6e-70 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_02465 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_02466 9.1e-40 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_02467 4.9e-78 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_02468 6.3e-63 hxlR K transcriptional
EBFKHPNK_02469 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
EBFKHPNK_02470 9.6e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
EBFKHPNK_02471 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
EBFKHPNK_02472 1.4e-68 nin S Competence protein J (ComJ)
EBFKHPNK_02473 1.2e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EBFKHPNK_02474 2.2e-51 S Protein of unknown function (DUF2680)
EBFKHPNK_02475 5.6e-74 yckC S membrane
EBFKHPNK_02476 2.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EBFKHPNK_02477 1.1e-228 yciC S GTPases (G3E family)
EBFKHPNK_02478 6.2e-224 nasA P COG2223 Nitrate nitrite transporter
EBFKHPNK_02479 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
EBFKHPNK_02480 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EBFKHPNK_02481 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBFKHPNK_02482 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
EBFKHPNK_02483 1.6e-279 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EBFKHPNK_02484 7.1e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EBFKHPNK_02485 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
EBFKHPNK_02486 1.1e-243 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBFKHPNK_02487 5.2e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EBFKHPNK_02488 2.3e-170 ycgM E Proline dehydrogenase
EBFKHPNK_02489 1.3e-145 ycgL S Predicted nucleotidyltransferase
EBFKHPNK_02490 1.3e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
EBFKHPNK_02491 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBFKHPNK_02492 6.1e-233 G COG0477 Permeases of the major facilitator superfamily
EBFKHPNK_02493 1.4e-147 4.2.1.118 G Xylose isomerase-like TIM barrel
EBFKHPNK_02494 2.3e-107 tmrB S AAA domain
EBFKHPNK_02496 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EBFKHPNK_02497 6.4e-113 ycgI S Domain of unknown function (DUF1989)
EBFKHPNK_02498 1.1e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
EBFKHPNK_02499 1.4e-149 yqcI S YqcI/YcgG family
EBFKHPNK_02500 4.7e-114 ycgF E Lysine exporter protein LysE YggA
EBFKHPNK_02501 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
EBFKHPNK_02502 2.8e-261 mdr EGP Major facilitator Superfamily
EBFKHPNK_02503 8.2e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EBFKHPNK_02504 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
EBFKHPNK_02505 3.1e-81 ycgB
EBFKHPNK_02506 9e-230 ycgA S Membrane
EBFKHPNK_02507 3.9e-212 amhX S amidohydrolase
EBFKHPNK_02508 3.1e-164 opuAC E glycine betaine
EBFKHPNK_02509 1.6e-138 opuAB P glycine betaine
EBFKHPNK_02510 4.3e-228 proV 3.6.3.32 E glycine betaine
EBFKHPNK_02511 4e-215 naiP P Uncharacterised MFS-type transporter YbfB
EBFKHPNK_02512 2.3e-193 yceH P Belongs to the TelA family
EBFKHPNK_02513 0.0 yceG S Putative component of 'biosynthetic module'
EBFKHPNK_02514 9.7e-138 terC P Protein of unknown function (DUF475)
EBFKHPNK_02515 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
EBFKHPNK_02516 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
EBFKHPNK_02517 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
EBFKHPNK_02518 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBFKHPNK_02519 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EBFKHPNK_02520 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EBFKHPNK_02521 8.7e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
EBFKHPNK_02522 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
EBFKHPNK_02523 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
EBFKHPNK_02524 1.3e-188 S response regulator aspartate phosphatase
EBFKHPNK_02525 8.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
EBFKHPNK_02526 8.2e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
EBFKHPNK_02527 6.3e-260 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
EBFKHPNK_02528 1.6e-177 ycdA S Domain of unknown function (DUF5105)
EBFKHPNK_02529 3.6e-171 yccK C Aldo keto reductase
EBFKHPNK_02530 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
EBFKHPNK_02531 3.4e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
EBFKHPNK_02532 5.2e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EBFKHPNK_02533 1.2e-100 yxaF K Transcriptional regulator
EBFKHPNK_02534 2.4e-238 lmrB EGP the major facilitator superfamily
EBFKHPNK_02535 1.7e-207 ycbU E Selenocysteine lyase
EBFKHPNK_02536 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EBFKHPNK_02537 7.5e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBFKHPNK_02538 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EBFKHPNK_02539 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
EBFKHPNK_02540 2.8e-78 sleB 3.5.1.28 M Cell wall
EBFKHPNK_02541 5.6e-62 ycbP S Protein of unknown function (DUF2512)
EBFKHPNK_02542 5.9e-55 traF CO Thioredoxin
EBFKHPNK_02543 1.3e-61 mhqP S DoxX
EBFKHPNK_02544 2.9e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
EBFKHPNK_02545 4e-110 ydfN C nitroreductase
EBFKHPNK_02546 1.2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EBFKHPNK_02547 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
EBFKHPNK_02548 3.4e-36 ycbJ S Macrolide 2'-phosphotransferase
EBFKHPNK_02549 5.7e-172 glnL T Regulator
EBFKHPNK_02550 2.2e-211 phoQ 2.7.13.3 T Histidine kinase
EBFKHPNK_02551 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
EBFKHPNK_02552 7.1e-259 agcS E Sodium alanine symporter
EBFKHPNK_02553 8.7e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
EBFKHPNK_02554 3.1e-257 mmuP E amino acid
EBFKHPNK_02555 9.5e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EBFKHPNK_02556 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EBFKHPNK_02557 2.3e-192 yceA S Belongs to the UPF0176 family
EBFKHPNK_02558 3.6e-42 ybfN
EBFKHPNK_02559 2.5e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EBFKHPNK_02560 3.2e-86 ybfM S SNARE associated Golgi protein
EBFKHPNK_02561 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBFKHPNK_02562 3.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EBFKHPNK_02563 3.6e-199 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EBFKHPNK_02564 1.2e-82 K Helix-turn-helix XRE-family like proteins
EBFKHPNK_02565 1.3e-30
EBFKHPNK_02566 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
EBFKHPNK_02568 1.9e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
EBFKHPNK_02569 1.3e-16 S Protein of unknown function (DUF2651)
EBFKHPNK_02570 1.7e-259 glpT G -transporter
EBFKHPNK_02571 1.1e-161 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EBFKHPNK_02572 1.2e-48 M PFAM Glycosyl transferase family 2
EBFKHPNK_02573 3.3e-292 ybeC E amino acid
EBFKHPNK_02574 9.2e-40 ybyB
EBFKHPNK_02575 5e-109 yqeB
EBFKHPNK_02576 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
EBFKHPNK_02577 7.2e-75 S Domain of unknown function (DUF4879)
EBFKHPNK_02578 2.7e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
EBFKHPNK_02579 0.0 Q TIGRFAM amino acid adenylation domain
EBFKHPNK_02580 1.5e-102 Q Flavin containing amine oxidoreductase
EBFKHPNK_02581 0.0 Q Polyketide synthase modules and related proteins
EBFKHPNK_02582 0.0 Q Beta-ketoacyl synthase
EBFKHPNK_02583 3.9e-120 fabD 2.3.1.39 I PFAM Acyl transferase
EBFKHPNK_02584 0.0 srfAC Q TIGRFAM amino acid adenylation domain
EBFKHPNK_02585 2.8e-59 bacT Q Thioesterase domain
EBFKHPNK_02586 4.4e-14
EBFKHPNK_02587 1.7e-122 V ABC-2 type transporter
EBFKHPNK_02588 3.1e-146 V ABC-2 type transporter
EBFKHPNK_02589 3.5e-134 V ABC transporter, ATP-binding protein
EBFKHPNK_02590 4.9e-82 KT helix_turn_helix, Lux Regulon
EBFKHPNK_02591 1.1e-103 T Histidine kinase
EBFKHPNK_02592 8.7e-93 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EBFKHPNK_02593 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
EBFKHPNK_02594 3.1e-69 yxaD K helix_turn_helix multiple antibiotic resistance protein
EBFKHPNK_02595 6.9e-52 S LrgA family
EBFKHPNK_02596 1.5e-92 yxaC M effector of murein hydrolase
EBFKHPNK_02597 1.2e-162 dkgB S Aldo/keto reductase family
EBFKHPNK_02598 1.9e-132 ybdO S Domain of unknown function (DUF4885)
EBFKHPNK_02599 2e-99 ybdN
EBFKHPNK_02600 4.4e-107 S ABC-2 family transporter protein
EBFKHPNK_02601 1.1e-153 V ATPases associated with a variety of cellular activities
EBFKHPNK_02602 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EBFKHPNK_02603 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBFKHPNK_02604 1.3e-223 ybbR S protein conserved in bacteria
EBFKHPNK_02605 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EBFKHPNK_02606 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EBFKHPNK_02607 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
EBFKHPNK_02610 5.6e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
EBFKHPNK_02611 3.1e-86 ybbJ J acetyltransferase
EBFKHPNK_02612 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EBFKHPNK_02613 1.3e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EBFKHPNK_02614 2.1e-246 yfeW 3.4.16.4 V Belongs to the UPF0214 family
EBFKHPNK_02615 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
EBFKHPNK_02616 3.9e-237 ybbC 3.2.1.52 S protein conserved in bacteria
EBFKHPNK_02617 2.2e-311 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
EBFKHPNK_02618 2e-172 feuA P Iron-uptake system-binding protein
EBFKHPNK_02619 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_02620 1.8e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_02621 3.5e-116 ybbA S Putative esterase
EBFKHPNK_02622 3.7e-174 ybaS 1.1.1.58 S Na -dependent transporter
EBFKHPNK_02623 6e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
EBFKHPNK_02624 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
EBFKHPNK_02625 2.2e-179 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
EBFKHPNK_02626 3.2e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EBFKHPNK_02627 3.8e-213 glcP G Major Facilitator Superfamily
EBFKHPNK_02629 1.6e-08
EBFKHPNK_02632 7.5e-77 ctsR K Belongs to the CtsR family
EBFKHPNK_02633 2.1e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
EBFKHPNK_02634 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EBFKHPNK_02635 0.0 clpC O Belongs to the ClpA ClpB family
EBFKHPNK_02636 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EBFKHPNK_02637 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EBFKHPNK_02638 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
EBFKHPNK_02639 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EBFKHPNK_02640 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EBFKHPNK_02641 2.4e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBFKHPNK_02642 1e-116 cysE 2.3.1.30 E Serine acetyltransferase
EBFKHPNK_02643 3.7e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EBFKHPNK_02644 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EBFKHPNK_02645 9.8e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBFKHPNK_02646 4.2e-89 yacP S RNA-binding protein containing a PIN domain
EBFKHPNK_02647 8.9e-116 sigH K Belongs to the sigma-70 factor family
EBFKHPNK_02648 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EBFKHPNK_02649 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
EBFKHPNK_02650 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBFKHPNK_02651 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EBFKHPNK_02652 2.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBFKHPNK_02653 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EBFKHPNK_02654 6.3e-108 rsmC 2.1.1.172 J Methyltransferase
EBFKHPNK_02655 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBFKHPNK_02656 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBFKHPNK_02657 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
EBFKHPNK_02658 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBFKHPNK_02659 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EBFKHPNK_02660 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EBFKHPNK_02661 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EBFKHPNK_02662 3.7e-187 ybaC 3.4.11.5 S Alpha/beta hydrolase family
EBFKHPNK_02663 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EBFKHPNK_02664 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EBFKHPNK_02665 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
EBFKHPNK_02666 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EBFKHPNK_02667 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBFKHPNK_02668 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EBFKHPNK_02669 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBFKHPNK_02670 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EBFKHPNK_02671 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBFKHPNK_02672 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
EBFKHPNK_02673 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBFKHPNK_02674 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBFKHPNK_02675 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBFKHPNK_02676 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EBFKHPNK_02677 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBFKHPNK_02678 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EBFKHPNK_02679 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EBFKHPNK_02680 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EBFKHPNK_02681 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBFKHPNK_02682 1.9e-23 rpmD J Ribosomal protein L30
EBFKHPNK_02683 1.1e-72 rplO J binds to the 23S rRNA
EBFKHPNK_02684 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EBFKHPNK_02685 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EBFKHPNK_02686 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
EBFKHPNK_02687 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBFKHPNK_02688 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EBFKHPNK_02689 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBFKHPNK_02690 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBFKHPNK_02691 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBFKHPNK_02692 4.7e-58 rplQ J Ribosomal protein L17
EBFKHPNK_02693 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EBFKHPNK_02694 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EBFKHPNK_02695 2.6e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EBFKHPNK_02696 1.6e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EBFKHPNK_02697 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBFKHPNK_02698 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EBFKHPNK_02699 9e-144 ybaJ Q Methyltransferase domain
EBFKHPNK_02700 3.6e-82 yizA S Damage-inducible protein DinB
EBFKHPNK_02701 1.7e-78 ybaK S Protein of unknown function (DUF2521)
EBFKHPNK_02702 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EBFKHPNK_02703 2.1e-196 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EBFKHPNK_02704 7.6e-76 gerD
EBFKHPNK_02705 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
EBFKHPNK_02706 1.1e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
EBFKHPNK_02709 2e-08
EBFKHPNK_02712 2.2e-30 csfB S Inhibitor of sigma-G Gin
EBFKHPNK_02713 2.1e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EBFKHPNK_02714 1.2e-192 yaaN P Belongs to the TelA family
EBFKHPNK_02715 6.2e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
EBFKHPNK_02716 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBFKHPNK_02717 7.5e-55 yaaQ S protein conserved in bacteria
EBFKHPNK_02718 1.2e-71 yaaR S protein conserved in bacteria
EBFKHPNK_02719 1.3e-182 holB 2.7.7.7 L DNA polymerase III
EBFKHPNK_02720 8.8e-145 yaaT S stage 0 sporulation protein
EBFKHPNK_02721 7.7e-37 yabA L Involved in initiation control of chromosome replication
EBFKHPNK_02722 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
EBFKHPNK_02723 4.7e-48 yazA L endonuclease containing a URI domain
EBFKHPNK_02724 2.4e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EBFKHPNK_02725 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
EBFKHPNK_02726 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBFKHPNK_02727 7.6e-143 tatD L hydrolase, TatD
EBFKHPNK_02728 3.1e-232 rpfB GH23 T protein conserved in bacteria
EBFKHPNK_02729 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EBFKHPNK_02730 1.1e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EBFKHPNK_02731 8.4e-146 yabG S peptidase
EBFKHPNK_02732 7.8e-39 veg S protein conserved in bacteria
EBFKHPNK_02733 2.9e-27 sspF S DNA topological change
EBFKHPNK_02734 4.6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EBFKHPNK_02735 3.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EBFKHPNK_02736 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
EBFKHPNK_02737 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EBFKHPNK_02738 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EBFKHPNK_02739 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EBFKHPNK_02740 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EBFKHPNK_02741 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EBFKHPNK_02742 3.7e-40 yabK S Peptide ABC transporter permease
EBFKHPNK_02743 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EBFKHPNK_02744 6.2e-91 spoVT K stage V sporulation protein
EBFKHPNK_02745 1.2e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EBFKHPNK_02746 3.8e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EBFKHPNK_02747 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EBFKHPNK_02748 1.9e-49 yabP S Sporulation protein YabP
EBFKHPNK_02749 4.4e-104 yabQ S spore cortex biosynthesis protein
EBFKHPNK_02750 4.1e-57 divIC D Septum formation initiator
EBFKHPNK_02751 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
EBFKHPNK_02754 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
EBFKHPNK_02755 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
EBFKHPNK_02756 1.8e-184 KLT serine threonine protein kinase
EBFKHPNK_02757 2.2e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EBFKHPNK_02758 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EBFKHPNK_02759 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBFKHPNK_02760 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EBFKHPNK_02761 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EBFKHPNK_02762 1.8e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
EBFKHPNK_02763 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EBFKHPNK_02764 4e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBFKHPNK_02765 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
EBFKHPNK_02766 2.9e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
EBFKHPNK_02767 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EBFKHPNK_02768 2.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBFKHPNK_02769 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EBFKHPNK_02770 4.5e-29 yazB K transcriptional
EBFKHPNK_02771 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBFKHPNK_02772 9.3e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EBFKHPNK_02773 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
EBFKHPNK_02774 3.6e-32 yaaL S Protein of unknown function (DUF2508)
EBFKHPNK_02775 5.1e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EBFKHPNK_02776 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EBFKHPNK_02777 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EBFKHPNK_02778 3e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EBFKHPNK_02779 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
EBFKHPNK_02780 5.8e-212 yaaH M Glycoside Hydrolase Family
EBFKHPNK_02781 4.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
EBFKHPNK_02782 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
EBFKHPNK_02783 3.3e-183 yaaC S YaaC-like Protein
EBFKHPNK_02784 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EBFKHPNK_02785 6.2e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EBFKHPNK_02786 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EBFKHPNK_02787 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EBFKHPNK_02788 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBFKHPNK_02789 1.5e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EBFKHPNK_02790 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EBFKHPNK_02791 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EBFKHPNK_02792 8.1e-38 yaaB S Domain of unknown function (DUF370)
EBFKHPNK_02793 3.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBFKHPNK_02794 2.4e-33 yaaA S S4 domain
EBFKHPNK_02795 2.3e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EBFKHPNK_02796 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EBFKHPNK_02797 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EBFKHPNK_02798 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EBFKHPNK_02799 5.5e-110 jag S single-stranded nucleic acid binding R3H
EBFKHPNK_02800 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EBFKHPNK_02801 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EBFKHPNK_02802 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EBFKHPNK_02803 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EBFKHPNK_02804 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
EBFKHPNK_02805 7.9e-149 spo0J K Belongs to the ParB family
EBFKHPNK_02806 6.2e-111 yyaC S Sporulation protein YyaC
EBFKHPNK_02807 4.8e-85 4.2.1.103 K FR47-like protein
EBFKHPNK_02808 4e-176 yyaD S Membrane
EBFKHPNK_02809 2.3e-33 yyzM S protein conserved in bacteria
EBFKHPNK_02810 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EBFKHPNK_02811 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EBFKHPNK_02812 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
EBFKHPNK_02813 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EBFKHPNK_02814 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EBFKHPNK_02815 9.3e-109 adaA 3.2.2.21 K Transcriptional regulator
EBFKHPNK_02816 5.8e-100 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EBFKHPNK_02817 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
EBFKHPNK_02818 1.2e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
EBFKHPNK_02819 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EBFKHPNK_02820 3.1e-248 ydjK G Sugar (and other) transporter
EBFKHPNK_02821 9.2e-164 yyaK S CAAX protease self-immunity
EBFKHPNK_02822 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
EBFKHPNK_02823 4.4e-129 ydfC EG EamA-like transporter family
EBFKHPNK_02824 6.7e-249 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EBFKHPNK_02825 7.6e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EBFKHPNK_02826 4.2e-164 K Transcriptional regulator
EBFKHPNK_02827 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
EBFKHPNK_02828 2.3e-164 eaeH M Domain of Unknown Function (DUF1259)
EBFKHPNK_02829 3.5e-76 yjcF S Acetyltransferase (GNAT) domain
EBFKHPNK_02830 5.6e-77 yybA 2.3.1.57 K transcriptional
EBFKHPNK_02831 1.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EBFKHPNK_02832 9.2e-69 ydgJ K Winged helix DNA-binding domain
EBFKHPNK_02833 5.6e-115 drgA C nitroreductase
EBFKHPNK_02834 3.8e-55 ypaA S Protein of unknown function (DUF1304)
EBFKHPNK_02835 5.7e-79 eamA1 EG spore germination
EBFKHPNK_02836 1.2e-161 G Major Facilitator Superfamily
EBFKHPNK_02837 1.3e-77 dinB S PFAM DinB family protein
EBFKHPNK_02838 1.3e-114 K FCD domain
EBFKHPNK_02839 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
EBFKHPNK_02840 8.5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
EBFKHPNK_02841 1.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EBFKHPNK_02842 2.5e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
EBFKHPNK_02843 2.8e-66 ydeP3 K Transcriptional regulator
EBFKHPNK_02844 6.5e-85 cotF M Spore coat protein
EBFKHPNK_02846 1.6e-158 yybS S membrane
EBFKHPNK_02847 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EBFKHPNK_02848 4.9e-73 rplI J binds to the 23S rRNA
EBFKHPNK_02849 3.6e-89 KLT COG0515 Serine threonine protein kinase
EBFKHPNK_02850 1.2e-120 S GlcNAc-PI de-N-acetylase
EBFKHPNK_02851 1.5e-234 M Glycosyltransferase Family 4
EBFKHPNK_02852 7.7e-235 S Carbamoyl-phosphate synthase L chain, ATP binding domain
EBFKHPNK_02853 3.4e-202 S Ecdysteroid kinase
EBFKHPNK_02854 1.2e-241 M Glycosyltransferase Family 4
EBFKHPNK_02855 1.1e-37 M 4-amino-4-deoxy-L-arabinose transferase activity
EBFKHPNK_02856 7.9e-17 yycC K YycC-like protein
EBFKHPNK_02858 1.4e-27 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
EBFKHPNK_02859 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EBFKHPNK_02860 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EBFKHPNK_02861 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBFKHPNK_02866 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_02867 0.0 vicK 2.7.13.3 T Histidine kinase
EBFKHPNK_02868 2.5e-261 yycH S protein conserved in bacteria
EBFKHPNK_02869 1.3e-151 yycI S protein conserved in bacteria
EBFKHPNK_02870 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EBFKHPNK_02871 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBFKHPNK_02872 1.6e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_02873 2.2e-252 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
EBFKHPNK_02874 7.1e-189 2.7.7.73, 2.7.7.80 H ThiF family
EBFKHPNK_02875 6.5e-259
EBFKHPNK_02876 2.6e-198 S Major Facilitator Superfamily
EBFKHPNK_02877 9.7e-305 S ABC transporter
EBFKHPNK_02878 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
EBFKHPNK_02879 2.2e-260 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EBFKHPNK_02880 2.2e-42 sdpR K transcriptional
EBFKHPNK_02881 8.5e-63 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EBFKHPNK_02882 5.9e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
EBFKHPNK_02883 4.5e-258 rocE E amino acid
EBFKHPNK_02884 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
EBFKHPNK_02885 5.2e-201 S Histidine kinase
EBFKHPNK_02887 2.8e-87 yycN 2.3.1.128 K Acetyltransferase
EBFKHPNK_02888 1.6e-185 C oxidoreductases (related to aryl-alcohol dehydrogenases)
EBFKHPNK_02889 1.4e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EBFKHPNK_02890 2.6e-214 yycP
EBFKHPNK_02893 7.9e-08 S YyzF-like protein
EBFKHPNK_02894 1.3e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EBFKHPNK_02896 2.8e-37
EBFKHPNK_02897 6.8e-13 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
EBFKHPNK_02898 5e-182 S Fusaric acid resistance protein-like
EBFKHPNK_02899 7.9e-188 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EBFKHPNK_02900 6.5e-92 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
EBFKHPNK_02901 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EBFKHPNK_02902 1.6e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EBFKHPNK_02903 9.8e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EBFKHPNK_02904 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
EBFKHPNK_02905 4.2e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
EBFKHPNK_02906 5e-229 XK27_00240 S Fic/DOC family
EBFKHPNK_02907 2.3e-287 ahpF O Alkyl hydroperoxide reductase
EBFKHPNK_02908 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
EBFKHPNK_02909 4e-127 E Ring-cleavage extradiol dioxygenase
EBFKHPNK_02910 1.5e-74 yxaI S membrane protein domain
EBFKHPNK_02911 6.9e-204 EGP Major facilitator Superfamily
EBFKHPNK_02912 3.9e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
EBFKHPNK_02913 5.1e-64 S Family of unknown function (DUF5391)
EBFKHPNK_02914 2.6e-140 S PQQ-like domain
EBFKHPNK_02915 2.8e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EBFKHPNK_02916 2.4e-217 yxbF K Bacterial regulatory proteins, tetR family
EBFKHPNK_02917 9e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
EBFKHPNK_02918 1e-199 desK 2.7.13.3 T Histidine kinase
EBFKHPNK_02919 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EBFKHPNK_02920 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
EBFKHPNK_02922 0.0 htpG O Molecular chaperone. Has ATPase activity
EBFKHPNK_02923 6.7e-246 csbC EGP Major facilitator Superfamily
EBFKHPNK_02924 4.9e-176 iolS C Aldo keto reductase
EBFKHPNK_02925 5.8e-135 iolR K COG1349 Transcriptional regulators of sugar metabolism
EBFKHPNK_02926 2.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EBFKHPNK_02927 2.2e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EBFKHPNK_02928 3.4e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EBFKHPNK_02929 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EBFKHPNK_02930 4e-175 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EBFKHPNK_02931 1.5e-231 iolF EGP Major facilitator Superfamily
EBFKHPNK_02932 4.7e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EBFKHPNK_02933 1.1e-166 iolH G Xylose isomerase-like TIM barrel
EBFKHPNK_02934 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EBFKHPNK_02935 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EBFKHPNK_02936 9.3e-130 S ABC-2 family transporter protein
EBFKHPNK_02937 2.3e-131 S permease
EBFKHPNK_02938 1e-162 bcrA V ABC transporter, ATP-binding protein
EBFKHPNK_02939 2.4e-138 T Transcriptional regulator
EBFKHPNK_02940 1.5e-272 T Histidine kinase
EBFKHPNK_02941 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_02942 3.9e-176 T PhoQ Sensor
EBFKHPNK_02943 5.5e-141 yxdL V ABC transporter, ATP-binding protein
EBFKHPNK_02944 0.0 yxdM V ABC transporter (permease)
EBFKHPNK_02945 2.2e-57 yxeA S Protein of unknown function (DUF1093)
EBFKHPNK_02946 5.9e-177 fhuD P Periplasmic binding protein
EBFKHPNK_02947 6e-35
EBFKHPNK_02948 8.4e-23 yxeD
EBFKHPNK_02949 6.4e-13 yxeE
EBFKHPNK_02952 3.4e-149 yidA S hydrolases of the HAD superfamily
EBFKHPNK_02953 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EBFKHPNK_02954 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EBFKHPNK_02955 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBFKHPNK_02956 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
EBFKHPNK_02957 2e-253 lysP E amino acid
EBFKHPNK_02958 3.4e-177 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EBFKHPNK_02959 2.7e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
EBFKHPNK_02960 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EBFKHPNK_02961 6.6e-287 hutH 4.3.1.3 E Histidine ammonia-lyase
EBFKHPNK_02962 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EBFKHPNK_02963 1.8e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EBFKHPNK_02964 5.5e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EBFKHPNK_02965 0.0 L HKD family nuclease
EBFKHPNK_02966 2e-71 yxiE T Belongs to the universal stress protein A family
EBFKHPNK_02967 7.9e-147 yxxF EG EamA-like transporter family
EBFKHPNK_02968 2.2e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
EBFKHPNK_02969 0.0 wapA M COG3209 Rhs family protein
EBFKHPNK_02970 2.5e-52
EBFKHPNK_02972 4.7e-36
EBFKHPNK_02975 3.1e-66 yxxG
EBFKHPNK_02976 5.1e-69 yxiG
EBFKHPNK_02980 2.8e-79
EBFKHPNK_02981 2e-104
EBFKHPNK_02982 3e-15 S YxiJ-like protein
EBFKHPNK_02983 3.2e-22
EBFKHPNK_02984 2.1e-48 yxiI S Protein of unknown function (DUF2716)
EBFKHPNK_02985 2.3e-60 S SMI1-KNR4 cell-wall
EBFKHPNK_02988 7.6e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EBFKHPNK_02989 8.4e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
EBFKHPNK_02990 7e-150 licT K transcriptional antiterminator
EBFKHPNK_02991 1.5e-143 exoK GH16 M licheninase activity
EBFKHPNK_02992 2.8e-222 citH C Citrate transporter
EBFKHPNK_02993 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
EBFKHPNK_02994 2.5e-177 L DNA synthesis involved in DNA repair
EBFKHPNK_02995 7.4e-46 yxiS
EBFKHPNK_02996 2.7e-75 T Domain of unknown function (DUF4163)
EBFKHPNK_02997 4.6e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBFKHPNK_02998 1.5e-158 rlmA 2.1.1.187 Q Methyltransferase domain
EBFKHPNK_02999 4.3e-219 yxjG 2.1.1.14 E Methionine synthase
EBFKHPNK_03000 1.2e-85 yxjI S LURP-one-related
EBFKHPNK_03003 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EBFKHPNK_03004 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EBFKHPNK_03005 3.8e-87 yxkC S Domain of unknown function (DUF4352)
EBFKHPNK_03006 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EBFKHPNK_03007 7.5e-166 lrp QT PucR C-terminal helix-turn-helix domain
EBFKHPNK_03008 2.6e-205 msmK P Belongs to the ABC transporter superfamily
EBFKHPNK_03009 1.3e-156 yxkH G Polysaccharide deacetylase
EBFKHPNK_03010 5.9e-215 cimH C COG3493 Na citrate symporter
EBFKHPNK_03011 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
EBFKHPNK_03012 1.6e-188 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
EBFKHPNK_03013 0.0 cydD V ATP-binding
EBFKHPNK_03014 2.6e-292 cydD V ATP-binding protein
EBFKHPNK_03015 2.5e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EBFKHPNK_03016 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
EBFKHPNK_03017 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EBFKHPNK_03018 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EBFKHPNK_03019 7.8e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
EBFKHPNK_03020 4.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
EBFKHPNK_03021 2.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
EBFKHPNK_03022 1.3e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EBFKHPNK_03023 3.7e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EBFKHPNK_03024 9.1e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
EBFKHPNK_03025 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
EBFKHPNK_03026 1.9e-226 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EBFKHPNK_03027 9.1e-59 arsR K transcriptional
EBFKHPNK_03028 4e-167 cbrA3 P Periplasmic binding protein
EBFKHPNK_03029 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_03030 1.4e-171 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_03031 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EBFKHPNK_03032 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
EBFKHPNK_03033 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
EBFKHPNK_03034 2.2e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EBFKHPNK_03035 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
EBFKHPNK_03036 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EBFKHPNK_03037 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EBFKHPNK_03038 1.4e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EBFKHPNK_03039 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_03040 8.2e-229 dltB M membrane protein involved in D-alanine export
EBFKHPNK_03041 2.5e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_03042 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
EBFKHPNK_03043 4.9e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EBFKHPNK_03044 6.5e-21 ywaC 2.7.6.5 S protein conserved in bacteria
EBFKHPNK_03045 1.9e-80 ywaC 2.7.6.5 S protein conserved in bacteria
EBFKHPNK_03046 3.3e-163 gspA M General stress
EBFKHPNK_03047 8.6e-267 epr 3.4.21.62 O Belongs to the peptidase S8 family
EBFKHPNK_03048 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EBFKHPNK_03049 3.8e-66 ywbC 4.4.1.5 E glyoxalase
EBFKHPNK_03050 9.4e-225 ywbD 2.1.1.191 J Methyltransferase
EBFKHPNK_03051 2.8e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
EBFKHPNK_03052 1.4e-141 mta K transcriptional
EBFKHPNK_03053 1.1e-26 ywbE S Uncharacterized conserved protein (DUF2196)
EBFKHPNK_03054 1.5e-110 ywbG M effector of murein hydrolase
EBFKHPNK_03055 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EBFKHPNK_03056 8.2e-152 ywbI K Transcriptional regulator
EBFKHPNK_03057 4.3e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EBFKHPNK_03058 6.1e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EBFKHPNK_03059 5.3e-242 ywbN P Dyp-type peroxidase family protein
EBFKHPNK_03060 1.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EBFKHPNK_03061 3.7e-133 S Streptomycin biosynthesis protein StrF
EBFKHPNK_03062 1.9e-129 H Methionine biosynthesis protein MetW
EBFKHPNK_03064 8.7e-113 ywcC K Bacterial regulatory proteins, tetR family
EBFKHPNK_03065 2.7e-62 gtcA S GtrA-like protein
EBFKHPNK_03066 5e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EBFKHPNK_03067 8.6e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EBFKHPNK_03068 8.4e-27 ywzA S membrane
EBFKHPNK_03069 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EBFKHPNK_03070 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBFKHPNK_03071 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EBFKHPNK_03072 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EBFKHPNK_03073 1.7e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
EBFKHPNK_03074 3.5e-78 ysnE K acetyltransferase
EBFKHPNK_03075 2.9e-213 rodA D Belongs to the SEDS family
EBFKHPNK_03076 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
EBFKHPNK_03077 6.8e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBFKHPNK_03078 0.0 vpr O Belongs to the peptidase S8 family
EBFKHPNK_03080 1.4e-150 sacT K transcriptional antiterminator
EBFKHPNK_03081 2e-07 sacT K transcriptional antiterminator
EBFKHPNK_03082 2.4e-248 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EBFKHPNK_03083 1.1e-280 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
EBFKHPNK_03084 9.7e-20 ywdA
EBFKHPNK_03085 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EBFKHPNK_03086 3.3e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
EBFKHPNK_03087 1.1e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBFKHPNK_03088 4.7e-41 ywdI S Family of unknown function (DUF5327)
EBFKHPNK_03089 7.5e-231 ywdJ F Xanthine uracil
EBFKHPNK_03090 4.2e-46 ywdK S small membrane protein
EBFKHPNK_03091 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EBFKHPNK_03092 2.6e-143 spsA M Spore Coat
EBFKHPNK_03093 2.2e-276 spsB M Capsule polysaccharide biosynthesis protein
EBFKHPNK_03094 7.4e-222 spsC E Belongs to the DegT DnrJ EryC1 family
EBFKHPNK_03095 5.5e-158 spsD 2.3.1.210 K Spore Coat
EBFKHPNK_03096 5.4e-214 spsE 2.5.1.56 M acid synthase
EBFKHPNK_03097 1e-136 spsF M Spore Coat
EBFKHPNK_03098 1.9e-186 spsG M Spore Coat
EBFKHPNK_03099 4.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EBFKHPNK_03100 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EBFKHPNK_03101 3.6e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EBFKHPNK_03102 1e-86 spsL 5.1.3.13 M Spore Coat
EBFKHPNK_03103 3.2e-59
EBFKHPNK_03104 2.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EBFKHPNK_03105 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EBFKHPNK_03106 0.0 rocB E arginine degradation protein
EBFKHPNK_03107 2.4e-259 lysP E amino acid
EBFKHPNK_03108 2.9e-205 tcaB EGP Major facilitator Superfamily
EBFKHPNK_03109 5.4e-223 ywfA EGP Major facilitator Superfamily
EBFKHPNK_03110 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EBFKHPNK_03111 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EBFKHPNK_03112 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_03113 1.3e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EBFKHPNK_03114 4.7e-208 bacE EGP Major facilitator Superfamily
EBFKHPNK_03115 1.1e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
EBFKHPNK_03116 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
EBFKHPNK_03117 1.1e-146 ywfI C May function as heme-dependent peroxidase
EBFKHPNK_03118 1.1e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
EBFKHPNK_03119 1.8e-157 MA20_14895 S Conserved hypothetical protein 698
EBFKHPNK_03120 6e-163 cysL K Transcriptional regulator
EBFKHPNK_03121 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EBFKHPNK_03123 1.2e-185
EBFKHPNK_03126 1.7e-168 yhcI S ABC transporter (permease)
EBFKHPNK_03127 1.6e-166 V ABC transporter, ATP-binding protein
EBFKHPNK_03128 3.1e-93 S membrane
EBFKHPNK_03129 4.8e-51 padR K PadR family transcriptional regulator
EBFKHPNK_03130 3e-110 rsfA_1
EBFKHPNK_03131 6.9e-36 ywzC S Belongs to the UPF0741 family
EBFKHPNK_03132 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
EBFKHPNK_03133 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
EBFKHPNK_03134 1.3e-246 yhdG_1 E C-terminus of AA_permease
EBFKHPNK_03135 8e-70 ywhA K Transcriptional regulator
EBFKHPNK_03136 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
EBFKHPNK_03137 3.6e-117 ywhC S Peptidase family M50
EBFKHPNK_03138 8.9e-95 ywhD S YwhD family
EBFKHPNK_03139 7.2e-82
EBFKHPNK_03140 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EBFKHPNK_03141 2e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EBFKHPNK_03142 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
EBFKHPNK_03145 8.1e-77 CP Membrane
EBFKHPNK_03147 2e-28 S Domain of unknown function (DUF4177)
EBFKHPNK_03148 5e-33
EBFKHPNK_03149 2.6e-29 ydcG K sequence-specific DNA binding
EBFKHPNK_03151 1.4e-76 S aspartate phosphatase
EBFKHPNK_03152 1.1e-42 ywiB S protein conserved in bacteria
EBFKHPNK_03153 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EBFKHPNK_03154 5.8e-214 narK P COG2223 Nitrate nitrite transporter
EBFKHPNK_03155 1.7e-128 fnr K helix_turn_helix, cAMP Regulatory protein
EBFKHPNK_03156 1e-136 ywiC S YwiC-like protein
EBFKHPNK_03157 1e-84 arfM T cyclic nucleotide binding
EBFKHPNK_03158 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EBFKHPNK_03159 2e-293 narH 1.7.5.1 C Nitrate reductase, beta
EBFKHPNK_03160 3.6e-94 narJ 1.7.5.1 C nitrate reductase
EBFKHPNK_03161 4.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
EBFKHPNK_03162 1.2e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EBFKHPNK_03163 1.1e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBFKHPNK_03164 0.0 ywjA V ABC transporter
EBFKHPNK_03165 1.6e-42 ywjC
EBFKHPNK_03166 4.7e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EBFKHPNK_03167 9.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EBFKHPNK_03168 0.0 fadF C COG0247 Fe-S oxidoreductase
EBFKHPNK_03169 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EBFKHPNK_03170 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EBFKHPNK_03171 1.7e-93 ywjG S Domain of unknown function (DUF2529)
EBFKHPNK_03172 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
EBFKHPNK_03173 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
EBFKHPNK_03174 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBFKHPNK_03175 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBFKHPNK_03176 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
EBFKHPNK_03177 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EBFKHPNK_03178 1.1e-32 rpmE J Binds the 23S rRNA
EBFKHPNK_03179 1.4e-104 tdk 2.7.1.21 F thymidine kinase
EBFKHPNK_03180 0.0 sfcA 1.1.1.38 C malic enzyme
EBFKHPNK_03181 3.6e-158 ywkB S Membrane transport protein
EBFKHPNK_03182 1.5e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EBFKHPNK_03183 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EBFKHPNK_03184 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBFKHPNK_03185 4.7e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EBFKHPNK_03187 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
EBFKHPNK_03188 8.9e-119 spoIIR S stage II sporulation protein R
EBFKHPNK_03189 6.7e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
EBFKHPNK_03190 2.3e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EBFKHPNK_03191 2e-84 mntP P Probably functions as a manganese efflux pump
EBFKHPNK_03192 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBFKHPNK_03193 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
EBFKHPNK_03194 1.7e-96 ywlG S Belongs to the UPF0340 family
EBFKHPNK_03195 3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBFKHPNK_03196 2.6e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EBFKHPNK_03197 2.1e-61 atpI S ATP synthase
EBFKHPNK_03198 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
EBFKHPNK_03199 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBFKHPNK_03200 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBFKHPNK_03201 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBFKHPNK_03202 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBFKHPNK_03203 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBFKHPNK_03204 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBFKHPNK_03205 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EBFKHPNK_03206 1.2e-90 ywmA
EBFKHPNK_03207 1.3e-32 ywzB S membrane
EBFKHPNK_03208 1.4e-133 ywmB S TATA-box binding
EBFKHPNK_03209 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBFKHPNK_03210 2.1e-188 spoIID D Stage II sporulation protein D
EBFKHPNK_03211 4.6e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
EBFKHPNK_03212 3e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
EBFKHPNK_03214 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EBFKHPNK_03215 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBFKHPNK_03216 2.2e-93 S response regulator aspartate phosphatase
EBFKHPNK_03217 2.1e-82 ywmF S Peptidase M50
EBFKHPNK_03218 7.4e-10 csbD K CsbD-like
EBFKHPNK_03219 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EBFKHPNK_03220 5e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EBFKHPNK_03221 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EBFKHPNK_03222 6.1e-67 ywnA K Transcriptional regulator
EBFKHPNK_03224 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
EBFKHPNK_03225 1.7e-53 ywnC S Family of unknown function (DUF5362)
EBFKHPNK_03226 8.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBFKHPNK_03227 4.2e-69 ywnF S Family of unknown function (DUF5392)
EBFKHPNK_03228 3.4e-10 ywnC S Family of unknown function (DUF5362)
EBFKHPNK_03229 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
EBFKHPNK_03230 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
EBFKHPNK_03231 6.6e-72 ywnJ S VanZ like family
EBFKHPNK_03232 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
EBFKHPNK_03233 1.4e-209 ftsW D Belongs to the SEDS family
EBFKHPNK_03234 5.9e-58 nrgB K Belongs to the P(II) protein family
EBFKHPNK_03235 2.5e-228 amt P Ammonium transporter
EBFKHPNK_03236 5.7e-103 phzA Q Isochorismatase family
EBFKHPNK_03237 5.7e-242 ywoD EGP Major facilitator superfamily
EBFKHPNK_03238 2.1e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
EBFKHPNK_03239 3.8e-213 ywoG EGP Major facilitator Superfamily
EBFKHPNK_03240 8.5e-72 ywoH K transcriptional
EBFKHPNK_03241 1.8e-44 spoIIID K Stage III sporulation protein D
EBFKHPNK_03242 2.7e-180 mbl D Rod shape-determining protein
EBFKHPNK_03243 3.2e-128 flhO N flagellar basal body
EBFKHPNK_03244 8.8e-145 flhP N flagellar basal body
EBFKHPNK_03245 1.5e-200 S aspartate phosphatase
EBFKHPNK_03246 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EBFKHPNK_03247 1.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EBFKHPNK_03248 3.9e-69 ywpF S YwpF-like protein
EBFKHPNK_03249 4e-62 ywpG
EBFKHPNK_03250 1.7e-57 ssbB L Single-stranded DNA-binding protein
EBFKHPNK_03251 7.5e-138 glcR K DeoR C terminal sensor domain
EBFKHPNK_03252 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
EBFKHPNK_03253 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EBFKHPNK_03254 7.8e-307 ywqB S SWIM zinc finger
EBFKHPNK_03255 1.3e-14
EBFKHPNK_03256 6.8e-112 ywqC M biosynthesis protein
EBFKHPNK_03257 8.2e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
EBFKHPNK_03258 4.6e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
EBFKHPNK_03259 1.4e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EBFKHPNK_03260 1.7e-150 ywqG S Domain of unknown function (DUF1963)
EBFKHPNK_03262 8.5e-22 S Domain of unknown function (DUF5082)
EBFKHPNK_03263 9.5e-37 ywqI S Family of unknown function (DUF5344)
EBFKHPNK_03264 1.2e-82 ywqJ S Pre-toxin TG
EBFKHPNK_03265 1.6e-61 ywqJ S Pre-toxin TG
EBFKHPNK_03266 2e-49
EBFKHPNK_03267 7.8e-33 IQ Enoyl-(Acyl carrier protein) reductase
EBFKHPNK_03269 2.2e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBFKHPNK_03270 1.5e-55 swrA S Swarming motility protein
EBFKHPNK_03271 1.8e-254 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
EBFKHPNK_03272 1.7e-225 ywoF P Right handed beta helix region
EBFKHPNK_03273 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EBFKHPNK_03274 1e-122 ftsE D cell division ATP-binding protein FtsE
EBFKHPNK_03275 2.4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
EBFKHPNK_03276 1.2e-149 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
EBFKHPNK_03277 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EBFKHPNK_03278 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EBFKHPNK_03279 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EBFKHPNK_03280 6.8e-68
EBFKHPNK_03281 3.5e-10 fliT S bacterial-type flagellum organization
EBFKHPNK_03282 1.2e-65 fliS N flagellar protein FliS
EBFKHPNK_03283 8.1e-245 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EBFKHPNK_03284 3.2e-92 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EBFKHPNK_03285 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EBFKHPNK_03286 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EBFKHPNK_03287 1.4e-80 yviE
EBFKHPNK_03288 6.1e-163 flgL N Belongs to the bacterial flagellin family
EBFKHPNK_03289 3.7e-274 flgK N flagellar hook-associated protein
EBFKHPNK_03290 3.4e-80 flgN NOU FlgN protein
EBFKHPNK_03291 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
EBFKHPNK_03292 1.4e-74 yvyF S flagellar protein
EBFKHPNK_03293 8.4e-67 comFC S Phosphoribosyl transferase domain
EBFKHPNK_03294 1.7e-42 comFB S Late competence development protein ComFB
EBFKHPNK_03295 7.1e-256 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EBFKHPNK_03296 1e-156 degV S protein conserved in bacteria
EBFKHPNK_03297 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EBFKHPNK_03298 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EBFKHPNK_03299 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
EBFKHPNK_03300 2e-166 yvhJ K Transcriptional regulator
EBFKHPNK_03301 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EBFKHPNK_03302 3.7e-237 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
EBFKHPNK_03303 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
EBFKHPNK_03304 1.7e-114 tuaF M protein involved in exopolysaccharide biosynthesis
EBFKHPNK_03305 5.5e-256 tuaE M Teichuronic acid biosynthesis protein
EBFKHPNK_03306 2.4e-248 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EBFKHPNK_03307 2.3e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
EBFKHPNK_03308 1e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EBFKHPNK_03309 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EBFKHPNK_03310 9.1e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EBFKHPNK_03311 3e-306 lytB 3.5.1.28 D Stage II sporulation protein
EBFKHPNK_03312 5.9e-30
EBFKHPNK_03313 9.4e-140 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EBFKHPNK_03314 7.8e-184 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EBFKHPNK_03315 3.7e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EBFKHPNK_03316 1.9e-180 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EBFKHPNK_03317 9.8e-136 tagG GM Transport permease protein
EBFKHPNK_03318 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EBFKHPNK_03319 2.6e-204 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
EBFKHPNK_03320 2.8e-27 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
EBFKHPNK_03321 2.2e-69 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
EBFKHPNK_03322 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EBFKHPNK_03323 6.5e-210 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EBFKHPNK_03324 2.6e-129 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EBFKHPNK_03325 3.5e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
EBFKHPNK_03326 4.6e-266 gerBA EG Spore germination protein
EBFKHPNK_03327 6.4e-199 gerBB E Spore germination protein
EBFKHPNK_03328 2.1e-213 gerAC S Spore germination protein
EBFKHPNK_03329 1.2e-266 GT2,GT4 J Glycosyl transferase family 2
EBFKHPNK_03330 1.9e-248 ywtG EGP Major facilitator Superfamily
EBFKHPNK_03331 7.2e-178 ywtF K Transcriptional regulator
EBFKHPNK_03332 5.5e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
EBFKHPNK_03333 4.5e-36 yttA 2.7.13.3 S Pfam Transposase IS66
EBFKHPNK_03334 2.8e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EBFKHPNK_03335 1.1e-19 ywtC
EBFKHPNK_03336 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EBFKHPNK_03337 2.3e-70 pgsC S biosynthesis protein
EBFKHPNK_03338 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
EBFKHPNK_03339 1.7e-183 gerKA EG Spore germination protein
EBFKHPNK_03340 1.7e-191 gerKB E Spore germination protein
EBFKHPNK_03341 4.7e-205 gerKC S Spore germination B3/ GerAC like, C-terminal
EBFKHPNK_03342 5e-179 rbsR K transcriptional
EBFKHPNK_03343 1.5e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBFKHPNK_03344 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EBFKHPNK_03345 1.1e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EBFKHPNK_03346 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
EBFKHPNK_03347 2e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
EBFKHPNK_03348 1.2e-89 batE T Sh3 type 3 domain protein
EBFKHPNK_03349 1.8e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
EBFKHPNK_03350 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
EBFKHPNK_03351 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EBFKHPNK_03352 2e-166 alsR K LysR substrate binding domain
EBFKHPNK_03353 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EBFKHPNK_03354 4.4e-126 ywrJ
EBFKHPNK_03355 1.5e-129 cotB
EBFKHPNK_03356 1.1e-211 cotH M Spore Coat
EBFKHPNK_03357 2e-09
EBFKHPNK_03358 3.3e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EBFKHPNK_03359 3.6e-07 S Domain of unknown function (DUF4181)
EBFKHPNK_03360 1.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EBFKHPNK_03361 1.1e-83 ywrC K Transcriptional regulator
EBFKHPNK_03362 1.2e-103 ywrB P Chromate transporter
EBFKHPNK_03363 1.7e-88 ywrA P COG2059 Chromate transport protein ChrA
EBFKHPNK_03364 5e-136 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EBFKHPNK_03365 2.2e-285 Q Non-ribosomal peptide synthetase modules and related proteins
EBFKHPNK_03366 1.6e-115 Q Non-ribosomal peptide synthetase modules and related proteins
EBFKHPNK_03367 1.2e-98 V ABC transporter transmembrane region
EBFKHPNK_03368 3.6e-50 E Saccharopine dehydrogenase
EBFKHPNK_03369 9.6e-176 S Psort location CytoplasmicMembrane, score
EBFKHPNK_03370 1.2e-49 bacT Q Thioesterase domain
EBFKHPNK_03371 8.7e-227 yvkA EGP Major facilitator Superfamily
EBFKHPNK_03372 6.9e-110 yvkB K Transcriptional regulator
EBFKHPNK_03373 0.0 yvkC 2.7.9.2 GT Phosphotransferase
EBFKHPNK_03374 7.6e-33 csbA S protein conserved in bacteria
EBFKHPNK_03375 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EBFKHPNK_03376 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EBFKHPNK_03377 3e-38 yvkN
EBFKHPNK_03378 6.1e-49 yvlA
EBFKHPNK_03379 9.2e-166 yvlB S Putative adhesin
EBFKHPNK_03380 9.6e-26 pspB KT PspC domain
EBFKHPNK_03381 3.9e-41 yvlD S Membrane
EBFKHPNK_03382 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
EBFKHPNK_03383 6.2e-105 yxaF K Transcriptional regulator
EBFKHPNK_03384 1.5e-132 yvoA K transcriptional
EBFKHPNK_03385 5.2e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EBFKHPNK_03386 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBFKHPNK_03387 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EBFKHPNK_03388 9.9e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBFKHPNK_03389 1.7e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EBFKHPNK_03390 4.4e-72 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
EBFKHPNK_03391 2.7e-137 yvpB NU protein conserved in bacteria
EBFKHPNK_03392 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EBFKHPNK_03393 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EBFKHPNK_03394 7.2e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EBFKHPNK_03395 3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EBFKHPNK_03396 3.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EBFKHPNK_03397 1.9e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBFKHPNK_03398 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EBFKHPNK_03399 3.1e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
EBFKHPNK_03400 0.0 msbA2 3.6.3.44 V ABC transporter
EBFKHPNK_03401 1e-57
EBFKHPNK_03402 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_03403 3.6e-191 sasA T Histidine kinase
EBFKHPNK_03404 2.9e-276 S COG0457 FOG TPR repeat
EBFKHPNK_03405 5e-124 usp CBM50 M protein conserved in bacteria
EBFKHPNK_03406 1e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EBFKHPNK_03407 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EBFKHPNK_03408 1.1e-166 rapZ S Displays ATPase and GTPase activities
EBFKHPNK_03409 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EBFKHPNK_03410 3.1e-170 whiA K May be required for sporulation
EBFKHPNK_03411 1.2e-36 crh G Phosphocarrier protein Chr
EBFKHPNK_03412 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
EBFKHPNK_03413 1.3e-78 M Ribonuclease
EBFKHPNK_03414 1.9e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBFKHPNK_03415 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EBFKHPNK_03416 2.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
EBFKHPNK_03417 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
EBFKHPNK_03418 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
EBFKHPNK_03419 5.8e-19 EGP Sugar (and other) transporter
EBFKHPNK_03420 6.8e-251 EGP Sugar (and other) transporter
EBFKHPNK_03421 4.9e-215 yraM S PrpF protein
EBFKHPNK_03422 6.7e-164 yraN K Transcriptional regulator
EBFKHPNK_03423 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EBFKHPNK_03424 3.3e-183 scrR K transcriptional
EBFKHPNK_03425 1.5e-217 rafB P LacY proton/sugar symporter
EBFKHPNK_03426 1.7e-295 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
EBFKHPNK_03428 3.1e-34
EBFKHPNK_03429 1.4e-238 I Pfam Lipase (class 3)
EBFKHPNK_03430 4.8e-41 S Protein of unknown function (DUF1433)
EBFKHPNK_03431 2e-16 S Protein of unknown function (DUF1433)
EBFKHPNK_03432 5.5e-94 padC Q Phenolic acid decarboxylase
EBFKHPNK_03433 1.6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EBFKHPNK_03434 1.7e-111 yyaS S Membrane
EBFKHPNK_03435 3.7e-96 ywjB H RibD C-terminal domain
EBFKHPNK_03436 4.9e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
EBFKHPNK_03437 1.9e-77 slr K transcriptional
EBFKHPNK_03438 3.8e-120 ywqC M biosynthesis protein
EBFKHPNK_03439 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
EBFKHPNK_03440 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
EBFKHPNK_03441 2.8e-218 epsD GT4 M Glycosyl transferase 4-like
EBFKHPNK_03442 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EBFKHPNK_03443 4.7e-213 epsF GT4 M Glycosyl transferases group 1
EBFKHPNK_03444 1e-204 epsG S EpsG family
EBFKHPNK_03445 2e-194 epsH GT2 S Glycosyltransferase like family 2
EBFKHPNK_03446 6.4e-204 epsI GM pyruvyl transferase
EBFKHPNK_03447 6.1e-196 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
EBFKHPNK_03448 1.8e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EBFKHPNK_03449 9.8e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EBFKHPNK_03450 7.8e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
EBFKHPNK_03451 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EBFKHPNK_03452 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
EBFKHPNK_03453 2.7e-32 yvfG S YvfG protein
EBFKHPNK_03454 1.9e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EBFKHPNK_03455 3.2e-303 yvfH C L-lactate permease
EBFKHPNK_03456 1.3e-120 yvfI K COG2186 Transcriptional regulators
EBFKHPNK_03457 2.3e-223 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EBFKHPNK_03458 2.5e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EBFKHPNK_03459 1.8e-270 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EBFKHPNK_03460 1.8e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EBFKHPNK_03461 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
EBFKHPNK_03462 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
EBFKHPNK_03463 5e-151 ybbH_1 K RpiR family transcriptional regulator
EBFKHPNK_03464 5.7e-166 3.1.3.104 S hydrolases of the HAD superfamily
EBFKHPNK_03465 4.5e-115 yyaS S Membrane
EBFKHPNK_03466 1.4e-181 purR7 5.1.1.1 K Transcriptional regulator
EBFKHPNK_03467 9e-261
EBFKHPNK_03468 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
EBFKHPNK_03469 7.7e-158 yvbV EG EamA-like transporter family
EBFKHPNK_03470 4.9e-125 yvbU K Transcriptional regulator
EBFKHPNK_03471 9.2e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBFKHPNK_03472 9.7e-42
EBFKHPNK_03473 2.2e-204 araR K transcriptional
EBFKHPNK_03474 7.4e-253 araE EGP Major facilitator Superfamily
EBFKHPNK_03476 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EBFKHPNK_03477 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EBFKHPNK_03478 1.1e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EBFKHPNK_03479 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EBFKHPNK_03480 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
EBFKHPNK_03481 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EBFKHPNK_03482 2.1e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
EBFKHPNK_03483 2.3e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EBFKHPNK_03484 2.8e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EBFKHPNK_03485 1.2e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
EBFKHPNK_03486 1.5e-236 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EBFKHPNK_03487 1.7e-149 M Protein involved in cellulose biosynthesis
EBFKHPNK_03488 2.5e-143 C WbqC-like protein family
EBFKHPNK_03489 9.8e-126 S GlcNAc-PI de-N-acetylase
EBFKHPNK_03490 1e-178
EBFKHPNK_03491 6.6e-213 EGP Major facilitator Superfamily
EBFKHPNK_03492 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
EBFKHPNK_03493 0.0 tcaA S response to antibiotic
EBFKHPNK_03494 7.6e-121 exoY M Membrane
EBFKHPNK_03495 1.5e-104 yvbG U UPF0056 membrane protein
EBFKHPNK_03496 7.1e-98 yvbF K Belongs to the GbsR family
EBFKHPNK_03497 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EBFKHPNK_03498 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EBFKHPNK_03499 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EBFKHPNK_03500 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EBFKHPNK_03501 4.3e-76 yvbF K Belongs to the GbsR family
EBFKHPNK_03502 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EBFKHPNK_03503 5.9e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EBFKHPNK_03504 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EBFKHPNK_03505 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
EBFKHPNK_03506 1e-69 K transcriptional
EBFKHPNK_03507 6e-35 yvzC K Transcriptional
EBFKHPNK_03508 4.8e-24 secG U Preprotein translocase subunit SecG
EBFKHPNK_03509 7.4e-143 est 3.1.1.1 S Carboxylesterase
EBFKHPNK_03510 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EBFKHPNK_03511 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBFKHPNK_03513 9.6e-45 yrdF K ribonuclease inhibitor
EBFKHPNK_03514 6.9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_03515 4.7e-160 ytlI K LysR substrate binding domain
EBFKHPNK_03516 3e-101 ytmI K Acetyltransferase (GNAT) domain
EBFKHPNK_03517 4.6e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
EBFKHPNK_03518 8.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
EBFKHPNK_03519 1.2e-121 tcyL P Binding-protein-dependent transport system inner membrane component
EBFKHPNK_03520 4.9e-120 tcyM U Binding-protein-dependent transport system inner membrane component
EBFKHPNK_03521 7.3e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EBFKHPNK_03522 6.5e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBFKHPNK_03523 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
EBFKHPNK_03524 2.4e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBFKHPNK_03525 4.4e-146 S Amidohydrolase
EBFKHPNK_03526 2.7e-70 4.1.1.44 S Carboxymuconolactone decarboxylase family
EBFKHPNK_03527 7.2e-220 ynfM EGP Major Facilitator Superfamily
EBFKHPNK_03528 6.2e-162 K Helix-turn-helix XRE-family like proteins
EBFKHPNK_03529 1.6e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EBFKHPNK_03530 2.7e-191 yvaA 1.1.1.371 S Oxidoreductase
EBFKHPNK_03531 6.3e-48 csoR S transcriptional
EBFKHPNK_03532 2.6e-29 copZ P Heavy-metal-associated domain
EBFKHPNK_03533 0.0 copA 3.6.3.54 P P-type ATPase
EBFKHPNK_03534 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EBFKHPNK_03535 1.2e-99 bdbD O Thioredoxin
EBFKHPNK_03536 2e-73 bdbC O Required for disulfide bond formation in some proteins
EBFKHPNK_03537 3.7e-140 S Metallo-peptidase family M12
EBFKHPNK_03538 3.1e-99 yvgT S membrane
EBFKHPNK_03539 0.0 helD 3.6.4.12 L DNA helicase
EBFKHPNK_03540 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EBFKHPNK_03541 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EBFKHPNK_03542 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
EBFKHPNK_03543 1.1e-86 yvgO
EBFKHPNK_03544 5e-156 yvgN S reductase
EBFKHPNK_03545 2e-200 yfiN V COG0842 ABC-type multidrug transport system, permease component
EBFKHPNK_03546 3.6e-194 yfiM V ABC-2 type transporter
EBFKHPNK_03547 5.6e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
EBFKHPNK_03548 1e-180 T Histidine kinase
EBFKHPNK_03549 2.4e-113 yfiK K Regulator
EBFKHPNK_03550 8.9e-94 modB P COG4149 ABC-type molybdate transport system, permease component
EBFKHPNK_03551 4.1e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
EBFKHPNK_03552 1.7e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
EBFKHPNK_03553 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EBFKHPNK_03554 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
EBFKHPNK_03555 3.6e-14 S Small spore protein J (Spore_SspJ)
EBFKHPNK_03556 2.9e-236 yvsH E Arginine ornithine antiporter
EBFKHPNK_03557 2e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EBFKHPNK_03558 1.2e-177 fhuD P ABC transporter
EBFKHPNK_03559 5.6e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_03560 1.2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_03561 1.8e-147 fhuC 3.6.3.34 HP ABC transporter
EBFKHPNK_03562 5.4e-66 yvrL S Regulatory protein YrvL
EBFKHPNK_03563 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
EBFKHPNK_03564 2.7e-15 S YvrJ protein family
EBFKHPNK_03565 9.9e-103 yvrI K RNA polymerase
EBFKHPNK_03566 1.1e-36
EBFKHPNK_03567 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_03568 0.0 T PhoQ Sensor
EBFKHPNK_03569 1.3e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
EBFKHPNK_03570 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_03571 2.5e-167 yvrC P ABC transporter substrate-binding protein
EBFKHPNK_03572 4.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBFKHPNK_03573 2.8e-224 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EBFKHPNK_03574 9.2e-101 yvqK 2.5.1.17 S Adenosyltransferase
EBFKHPNK_03575 8.3e-227 yvqJ EGP Major facilitator Superfamily
EBFKHPNK_03576 3.3e-46 liaI S membrane
EBFKHPNK_03577 5.8e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EBFKHPNK_03578 5.3e-116 liaG S Putative adhesin
EBFKHPNK_03579 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
EBFKHPNK_03580 5.1e-193 vraS 2.7.13.3 T Histidine kinase
EBFKHPNK_03581 3.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EBFKHPNK_03582 7.5e-208 gerAC S Spore germination B3/ GerAC like, C-terminal
EBFKHPNK_03583 1.9e-187 gerAB E Spore germination protein
EBFKHPNK_03584 1.4e-259 gerAA EG Spore germination protein
EBFKHPNK_03585 6.6e-24 S Protein of unknown function (DUF3970)
EBFKHPNK_03586 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EBFKHPNK_03587 2.7e-158 yuxN K Transcriptional regulator
EBFKHPNK_03588 3.4e-24
EBFKHPNK_03589 7.9e-252 cssS 2.7.13.3 T PhoQ Sensor
EBFKHPNK_03590 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EBFKHPNK_03591 8.7e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBFKHPNK_03592 1.6e-79 dps P Belongs to the Dps family
EBFKHPNK_03593 9.9e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_03594 0.0 pepF2 E COG1164 Oligoendopeptidase F
EBFKHPNK_03595 1.2e-44 S YusW-like protein
EBFKHPNK_03596 3.1e-150 yusV 3.6.3.34 HP ABC transporter
EBFKHPNK_03597 3.3e-39 yusU S Protein of unknown function (DUF2573)
EBFKHPNK_03598 3.3e-189 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EBFKHPNK_03599 5e-139 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
EBFKHPNK_03600 4.7e-160 ywbI2 K Transcriptional regulator
EBFKHPNK_03601 1e-159 yusT K LysR substrate binding domain
EBFKHPNK_03602 5.3e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_03603 3.2e-65 yusQ S Tautomerase enzyme
EBFKHPNK_03604 8.1e-288 yusP P Major facilitator superfamily
EBFKHPNK_03605 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
EBFKHPNK_03606 3.2e-53 yusN M Coat F domain
EBFKHPNK_03607 3.9e-43
EBFKHPNK_03608 1.8e-210 yusP P Major facilitator superfamily
EBFKHPNK_03609 2.6e-166 fadM E Proline dehydrogenase
EBFKHPNK_03610 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
EBFKHPNK_03611 1.6e-216 fadA 2.3.1.16 I Belongs to the thiolase family
EBFKHPNK_03612 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
EBFKHPNK_03613 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
EBFKHPNK_03614 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EBFKHPNK_03615 2.4e-39 yusG S Protein of unknown function (DUF2553)
EBFKHPNK_03616 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
EBFKHPNK_03617 1.6e-54 yusE CO Thioredoxin
EBFKHPNK_03618 5e-57 yusD S SCP-2 sterol transfer family
EBFKHPNK_03619 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EBFKHPNK_03620 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
EBFKHPNK_03621 8.7e-145 metQ P Belongs to the NlpA lipoprotein family
EBFKHPNK_03622 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EBFKHPNK_03623 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EBFKHPNK_03624 1.2e-244 sufD O assembly protein SufD
EBFKHPNK_03625 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EBFKHPNK_03626 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
EBFKHPNK_03627 3e-270 sufB O FeS cluster assembly
EBFKHPNK_03628 2.5e-155 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EBFKHPNK_03629 7.2e-80 yncE S Protein of unknown function (DUF2691)
EBFKHPNK_03630 9.2e-127 Q ubiE/COQ5 methyltransferase family
EBFKHPNK_03631 3.6e-202 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
EBFKHPNK_03632 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
EBFKHPNK_03635 1.3e-165 K helix_turn_helix, mercury resistance
EBFKHPNK_03636 2.1e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EBFKHPNK_03637 8.9e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
EBFKHPNK_03638 2.6e-158 yurN G Binding-protein-dependent transport system inner membrane component
EBFKHPNK_03639 6.9e-164 yurM P COG0395 ABC-type sugar transport system, permease component
EBFKHPNK_03640 4.1e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
EBFKHPNK_03641 3.6e-134 yurK K UTRA
EBFKHPNK_03642 9.2e-206 msmX P Belongs to the ABC transporter superfamily
EBFKHPNK_03643 1.2e-168 bsn L Ribonuclease
EBFKHPNK_03644 7.3e-236 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EBFKHPNK_03645 1.6e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EBFKHPNK_03646 1.7e-213 blt EGP Major facilitator Superfamily
EBFKHPNK_03647 6.3e-19 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EBFKHPNK_03648 1.3e-18
EBFKHPNK_03649 4.3e-14
EBFKHPNK_03651 7.9e-14 yqbD 2.1.1.72 L Putative phage serine protease XkdF
EBFKHPNK_03652 3.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
EBFKHPNK_03653 1.7e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EBFKHPNK_03654 1.3e-60 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
EBFKHPNK_03655 2.2e-167 yunF S Protein of unknown function DUF72
EBFKHPNK_03656 1.8e-145 yunE S membrane transporter protein
EBFKHPNK_03657 3.1e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EBFKHPNK_03658 9.6e-130 yunB S Sporulation protein YunB (Spo_YunB)
EBFKHPNK_03659 6.4e-195 lytH M Peptidase, M23
EBFKHPNK_03660 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EBFKHPNK_03661 1.7e-47 yutD S protein conserved in bacteria
EBFKHPNK_03662 1.6e-73 yutE S Protein of unknown function DUF86
EBFKHPNK_03663 8.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EBFKHPNK_03664 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
EBFKHPNK_03665 9.3e-197 yutH S Spore coat protein
EBFKHPNK_03666 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
EBFKHPNK_03667 2.6e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBFKHPNK_03668 8.9e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EBFKHPNK_03669 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
EBFKHPNK_03670 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
EBFKHPNK_03671 1.1e-53 yuzD S protein conserved in bacteria
EBFKHPNK_03672 7.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
EBFKHPNK_03673 2.4e-39 yuzB S Belongs to the UPF0349 family
EBFKHPNK_03674 3.8e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBFKHPNK_03675 1.6e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EBFKHPNK_03676 1.1e-62 erpA S Belongs to the HesB IscA family
EBFKHPNK_03677 2.2e-134 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_03678 7.2e-95 rimJ 2.3.1.128 J Alanine acetyltransferase
EBFKHPNK_03680 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
EBFKHPNK_03682 3.3e-124 V ABC transporter
EBFKHPNK_03683 3.1e-71 CP Membrane
EBFKHPNK_03684 4.8e-29
EBFKHPNK_03685 4.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EBFKHPNK_03687 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
EBFKHPNK_03688 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
EBFKHPNK_03689 9.9e-28 yuiB S Putative membrane protein
EBFKHPNK_03690 4.2e-118 yuiC S protein conserved in bacteria
EBFKHPNK_03691 2.7e-77 yuiD S protein conserved in bacteria
EBFKHPNK_03692 1.3e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBFKHPNK_03693 3.7e-209 yuiF S antiporter
EBFKHPNK_03694 1.1e-101 bioY S Biotin biosynthesis protein
EBFKHPNK_03695 1.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
EBFKHPNK_03696 1.6e-165 besA S Putative esterase
EBFKHPNK_03697 8.7e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EBFKHPNK_03698 3.1e-223 entC 5.4.4.2 HQ Isochorismate synthase
EBFKHPNK_03699 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
EBFKHPNK_03700 5.5e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
EBFKHPNK_03701 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EBFKHPNK_03702 1.3e-34 mbtH S MbtH-like protein
EBFKHPNK_03703 2.8e-133 yukJ S Uncharacterized conserved protein (DUF2278)
EBFKHPNK_03704 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
EBFKHPNK_03705 1.5e-228 yukF QT Transcriptional regulator
EBFKHPNK_03706 2.8e-45 esxA S Belongs to the WXG100 family
EBFKHPNK_03707 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
EBFKHPNK_03708 3.1e-205 essB S WXG100 protein secretion system (Wss), protein YukC
EBFKHPNK_03709 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EBFKHPNK_03710 0.0 esaA S type VII secretion protein EsaA
EBFKHPNK_03711 6.9e-78 yueC S Family of unknown function (DUF5383)
EBFKHPNK_03712 1.1e-127 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EBFKHPNK_03713 3.7e-96 yueE S phosphohydrolase
EBFKHPNK_03714 1.6e-22 S Protein of unknown function (DUF2642)
EBFKHPNK_03715 1.9e-187 yueF S transporter activity
EBFKHPNK_03716 6.4e-34 yueG S Spore germination protein gerPA/gerPF
EBFKHPNK_03717 2.8e-38 yueH S YueH-like protein
EBFKHPNK_03718 7.2e-68 yueI S Protein of unknown function (DUF1694)
EBFKHPNK_03719 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
EBFKHPNK_03720 2.1e-282 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EBFKHPNK_03721 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
EBFKHPNK_03722 8.9e-51 yuzC
EBFKHPNK_03724 1.3e-88 comQ H Polyprenyl synthetase
EBFKHPNK_03726 5.4e-309 comP 2.7.13.3 T Histidine kinase
EBFKHPNK_03727 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EBFKHPNK_03728 4.6e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
EBFKHPNK_03729 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
EBFKHPNK_03730 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EBFKHPNK_03731 9.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EBFKHPNK_03732 7.6e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EBFKHPNK_03733 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EBFKHPNK_03734 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EBFKHPNK_03735 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EBFKHPNK_03736 1.1e-12
EBFKHPNK_03737 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
EBFKHPNK_03738 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
EBFKHPNK_03739 8.6e-287 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EBFKHPNK_03740 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EBFKHPNK_03741 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
EBFKHPNK_03742 1.5e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EBFKHPNK_03743 9.3e-74 yufK S Family of unknown function (DUF5366)
EBFKHPNK_03744 2.2e-72 yuxK S protein conserved in bacteria
EBFKHPNK_03745 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
EBFKHPNK_03746 1.9e-175 yuxJ EGP Major facilitator Superfamily
EBFKHPNK_03747 3.5e-118 kapD L the KinA pathway to sporulation
EBFKHPNK_03748 6.9e-68 kapB G Kinase associated protein B
EBFKHPNK_03749 4.7e-230 T PhoQ Sensor
EBFKHPNK_03750 4.2e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EBFKHPNK_03751 3.2e-40 yugE S Domain of unknown function (DUF1871)
EBFKHPNK_03752 1.1e-155 yugF I Hydrolase
EBFKHPNK_03753 2e-83 alaR K Transcriptional regulator
EBFKHPNK_03754 3.6e-208 yugH 2.6.1.1 E Aminotransferase
EBFKHPNK_03755 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
EBFKHPNK_03756 1.8e-34 yuzA S Domain of unknown function (DUF378)
EBFKHPNK_03757 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
EBFKHPNK_03758 3.1e-228 yugK C Dehydrogenase
EBFKHPNK_03759 1.4e-118 ycaC Q Isochorismatase family
EBFKHPNK_03760 4.7e-97 S NADPH-dependent FMN reductase
EBFKHPNK_03761 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
EBFKHPNK_03763 2.2e-72 yugN S YugN-like family
EBFKHPNK_03764 1.8e-181 yugO P COG1226 Kef-type K transport systems
EBFKHPNK_03765 1.1e-26 mstX S Membrane-integrating protein Mistic
EBFKHPNK_03766 2e-18
EBFKHPNK_03767 8.3e-117 yugP S Zn-dependent protease
EBFKHPNK_03768 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
EBFKHPNK_03769 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
EBFKHPNK_03770 6.8e-77 yugU S Uncharacterised protein family UPF0047
EBFKHPNK_03771 1e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EBFKHPNK_03772 4.8e-41
EBFKHPNK_03773 3.8e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
EBFKHPNK_03774 1.4e-220 mcpA NT chemotaxis protein
EBFKHPNK_03775 8.6e-239 mcpA NT chemotaxis protein
EBFKHPNK_03776 1.6e-224 mcpA NT chemotaxis protein
EBFKHPNK_03777 1.1e-236 mcpA NT chemotaxis protein
EBFKHPNK_03778 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
EBFKHPNK_03779 2.1e-185 ygjR S Oxidoreductase
EBFKHPNK_03780 7.6e-195 yubA S transporter activity
EBFKHPNK_03781 8.8e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EBFKHPNK_03783 1.7e-51 yjcN
EBFKHPNK_03784 1.9e-123 G Cupin
EBFKHPNK_03785 4.1e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EBFKHPNK_03786 4.8e-146 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EBFKHPNK_03787 2.7e-120 ktrA P COG0569 K transport systems, NAD-binding component
EBFKHPNK_03788 2.7e-94 yuaB
EBFKHPNK_03789 2.3e-96 yuaC K Belongs to the GbsR family
EBFKHPNK_03790 3.2e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
EBFKHPNK_03791 6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
EBFKHPNK_03792 2.5e-109 yuaD S MOSC domain
EBFKHPNK_03793 7.4e-83 yuaE S DinB superfamily
EBFKHPNK_03794 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
EBFKHPNK_03795 1.1e-177 yuaG 3.4.21.72 S protein conserved in bacteria
EBFKHPNK_03796 9.7e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
EBFKHPNK_03798 1.6e-08
EBFKHPNK_03810 1.1e-38 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EBFKHPNK_03811 3e-137 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
EBFKHPNK_03812 1.2e-123 yoqW S Belongs to the SOS response-associated peptidase family
EBFKHPNK_03815 1.1e-19 S YopX protein
EBFKHPNK_03819 7.2e-18
EBFKHPNK_03820 5.4e-52 V Abortive infection bacteriophage resistance protein
EBFKHPNK_03821 2.8e-72 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EBFKHPNK_03822 6.3e-28 xhlB S SPP1 phage holin
EBFKHPNK_03823 2.4e-30 xhlA S Haemolysin XhlA
EBFKHPNK_03828 4.9e-226 S peptidoglycan catabolic process
EBFKHPNK_03829 3.5e-47
EBFKHPNK_03830 3.4e-125
EBFKHPNK_03831 4.3e-25 S Phage tail assembly chaperone protein, TAC
EBFKHPNK_03832 9.4e-09 chiA 3.2.1.14 GH18 G Belongs to the glycosyl hydrolase 18 family
EBFKHPNK_03833 3.4e-33 N Bacterial Ig-like domain 2
EBFKHPNK_03834 5.9e-30 S Protein of unknown function (DUF3168)
EBFKHPNK_03835 3.6e-38 S Bacteriophage HK97-gp10, putative tail-component
EBFKHPNK_03836 1.2e-28 S Phage head-tail joining protein
EBFKHPNK_03837 6e-27 S Phage gp6-like head-tail connector protein
EBFKHPNK_03840 2.4e-143 S Phage capsid family
EBFKHPNK_03841 1.8e-59 S Domain of unknown function (DUF4355)
EBFKHPNK_03843 2.6e-92 S Phage Mu protein F like protein
EBFKHPNK_03844 1.3e-196 S Phage portal protein, SPP1 Gp6-like
EBFKHPNK_03845 1.1e-180 ps334 S Terminase-like family
EBFKHPNK_03846 4.2e-77 yqaS L DNA packaging
EBFKHPNK_03849 3.9e-12 K Transcriptional regulator
EBFKHPNK_03851 9.3e-68 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EBFKHPNK_03854 1.4e-71 L Phage integrase family
EBFKHPNK_03856 1.4e-10 K Helix-turn-helix domain
EBFKHPNK_03857 4.9e-62
EBFKHPNK_03860 2.4e-62
EBFKHPNK_03861 6.3e-225
EBFKHPNK_03865 4.9e-31
EBFKHPNK_03866 2.3e-48
EBFKHPNK_03867 3.3e-64
EBFKHPNK_03871 4.5e-46 S dUTPase
EBFKHPNK_03875 5.1e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EBFKHPNK_03876 1.7e-64 S Pfam:Phage_holin_4_1
EBFKHPNK_03879 1.3e-136 S Domain of unknown function (DUF2479)
EBFKHPNK_03880 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
EBFKHPNK_03881 2.5e-226 NU Prophage endopeptidase tail
EBFKHPNK_03882 5.5e-110 S Phage tail protein
EBFKHPNK_03883 0.0 S peptidoglycan catabolic process
EBFKHPNK_03884 2.5e-11
EBFKHPNK_03885 3.5e-23
EBFKHPNK_03886 9.9e-61
EBFKHPNK_03887 5.7e-30
EBFKHPNK_03888 6.7e-47 S Bacteriophage HK97-gp10, putative tail-component
EBFKHPNK_03889 8e-26 S Phage head-tail joining protein
EBFKHPNK_03890 5.3e-24 S Phage gp6-like head-tail connector protein
EBFKHPNK_03891 2.3e-40 S peptidoglycan catabolic process
EBFKHPNK_03893 8.3e-221 S peptidase activity
EBFKHPNK_03894 9.1e-110 S peptidase activity
EBFKHPNK_03895 4.9e-240 S Phage portal protein
EBFKHPNK_03896 6.7e-10
EBFKHPNK_03897 9.7e-231 S Phage Terminase
EBFKHPNK_03898 3.3e-68 S Phage terminase, small subunit
EBFKHPNK_03899 1.5e-23
EBFKHPNK_03900 3e-68 S HNH endonuclease
EBFKHPNK_03903 8.8e-77 L Phage integrase family
EBFKHPNK_03904 8.2e-52 wecC 1.1.1.336 M ArpU family transcriptional regulator
EBFKHPNK_03908 1.3e-46
EBFKHPNK_03913 1.8e-13 S YopX protein
EBFKHPNK_03914 5.1e-45 S dUTPase
EBFKHPNK_03915 2.2e-61 spaC2 V PFAM Lanthionine synthetase
EBFKHPNK_03917 4.1e-56
EBFKHPNK_03918 3.5e-35 yobL S Bacterial EndoU nuclease
EBFKHPNK_03919 1.2e-84 S Phage tail protein
EBFKHPNK_03920 4.9e-63 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EBFKHPNK_03921 2.5e-116 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBFKHPNK_03922 7.2e-26
EBFKHPNK_03923 2.9e-27 O Glutaredoxin
EBFKHPNK_03925 7.4e-71 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EBFKHPNK_03928 2.1e-50 S Protein of unknown function (DUF1643)
EBFKHPNK_03929 2.7e-149 S Thymidylate synthase
EBFKHPNK_03930 2.9e-29 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EBFKHPNK_03934 3.5e-09
EBFKHPNK_03937 2.9e-23 sspB S spore protein
EBFKHPNK_03938 4.5e-149 S Calcineurin-like phosphoesterase
EBFKHPNK_03945 6.6e-14 S Macro domain
EBFKHPNK_03946 3.1e-19 S Macro domain
EBFKHPNK_03948 2.4e-90 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EBFKHPNK_03951 6.5e-161 T His Kinase A (phosphoacceptor) domain
EBFKHPNK_03952 1.5e-102 K Transcriptional regulatory protein, C terminal
EBFKHPNK_03953 8.6e-86 mutG S ABC-2 family transporter protein
EBFKHPNK_03954 2e-87 spaE S ABC-2 family transporter protein
EBFKHPNK_03955 3e-101 mutF V ABC transporter, ATP-binding protein
EBFKHPNK_03958 9.7e-197 spaB S Lantibiotic dehydratase, C terminus
EBFKHPNK_03959 2.5e-155 spaT V ABC transporter
EBFKHPNK_03960 2.7e-34 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EBFKHPNK_03961 2.7e-82
EBFKHPNK_03962 5.5e-15 L GIY-YIG type nucleases (URI domain)
EBFKHPNK_03963 0.0
EBFKHPNK_03967 1.4e-60 ftsZ D Tubulin/FtsZ family, GTPase domain
EBFKHPNK_03970 1.3e-155
EBFKHPNK_03972 3.2e-199 3.1.21.3 L Domain of unknown function (DUF4942)
EBFKHPNK_03984 3.6e-21 I Acyltransferase family
EBFKHPNK_03985 8.5e-46
EBFKHPNK_03986 1.6e-08 K Cro/C1-type HTH DNA-binding domain
EBFKHPNK_04000 3.2e-35
EBFKHPNK_04001 1.6e-75
EBFKHPNK_04007 5.4e-38 L Belongs to the 'phage' integrase family
EBFKHPNK_04008 1.7e-133
EBFKHPNK_04009 3e-46
EBFKHPNK_04010 6.3e-33
EBFKHPNK_04011 2.8e-13 K Transcriptional regulator
EBFKHPNK_04015 2.1e-42
EBFKHPNK_04024 3.5e-83 S Protein of unknown function (DUF1273)
EBFKHPNK_04029 9.2e-27
EBFKHPNK_04031 1.3e-71
EBFKHPNK_04034 2.6e-93
EBFKHPNK_04035 4.7e-282 M Pectate lyase superfamily protein
EBFKHPNK_04036 1.3e-76 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EBFKHPNK_04038 2.3e-32 S Bacteriophage holin
EBFKHPNK_04040 5.1e-90 S response regulator aspartate phosphatase
EBFKHPNK_04042 4.2e-223 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EBFKHPNK_04043 3.1e-40 S YolD-like protein
EBFKHPNK_04044 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBFKHPNK_04045 3.1e-55 S NrdI Flavodoxin like
EBFKHPNK_04051 9.9e-12 larC 4.99.1.12 FJ Protein conserved in bacteria
EBFKHPNK_04060 1.1e-10
EBFKHPNK_04063 2.2e-09
EBFKHPNK_04067 3.4e-64 S ATPases associated with a variety of cellular activities
EBFKHPNK_04070 2.4e-68 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
EBFKHPNK_04072 1.2e-23 DR0488 S protein conserved in bacteria
EBFKHPNK_04073 2.5e-290 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
EBFKHPNK_04074 1.1e-171 S PD-(D/E)XK nuclease superfamily
EBFKHPNK_04075 5.5e-149 3.6.4.12 L DNA primase activity
EBFKHPNK_04076 3.6e-242 3.6.4.12 L DnaB-like helicase C terminal domain
EBFKHPNK_04078 5e-159 S AAA domain
EBFKHPNK_04079 1.5e-169
EBFKHPNK_04080 1.2e-70 nrnB S phosphohydrolase (DHH superfamily)
EBFKHPNK_04084 1.7e-222 M Parallel beta-helix repeats
EBFKHPNK_04085 1.3e-84 S Pfam:DUF867
EBFKHPNK_04086 2.8e-93
EBFKHPNK_04087 6.9e-72 S SMI1 / KNR4 family
EBFKHPNK_04088 1.9e-66 S SMI1 / KNR4 family (SUKH-1)
EBFKHPNK_04089 4.2e-103 S Domain of unknown function (DUF1851)
EBFKHPNK_04090 4.2e-42 ywqJ S LXG domain of WXG superfamily
EBFKHPNK_04091 5.7e-76 S Phage integrase family
EBFKHPNK_04092 4.1e-30 yqaB E IrrE N-terminal-like domain
EBFKHPNK_04093 3.2e-37 S Domain of unknown function (DUF4352)
EBFKHPNK_04094 1.8e-15 K Helix-turn-helix XRE-family like proteins
EBFKHPNK_04095 1.5e-12 K Helix-turn-helix XRE-family like proteins
EBFKHPNK_04096 1.2e-19
EBFKHPNK_04097 1.7e-46 S Phage regulatory protein Rha (Phage_pRha)
EBFKHPNK_04098 4.2e-85
EBFKHPNK_04101 4.6e-07 S Hypothetical protein Yqai
EBFKHPNK_04104 7.7e-153 yqaJ L YqaJ-like viral recombinase domain
EBFKHPNK_04105 5.6e-131 recT L RecT family
EBFKHPNK_04106 2.4e-29 3.1.3.16 L DnaD domain protein
EBFKHPNK_04107 1.2e-119 xkdC L IstB-like ATP binding protein
EBFKHPNK_04111 6.8e-54 S Protein of unknown function (DUF1064)
EBFKHPNK_04113 5e-17 yqaO S Phage-like element PBSX protein XtrA
EBFKHPNK_04118 3e-59 yokK S SMI1 / KNR4 family
EBFKHPNK_04119 8e-61 S Protein of unknown function, DUF600
EBFKHPNK_04120 1.2e-74 L nucleic acid phosphodiester bond hydrolysis
EBFKHPNK_04122 3.1e-215 S hydrolase activity
EBFKHPNK_04125 3.5e-18
EBFKHPNK_04126 8.7e-110
EBFKHPNK_04127 1.1e-18
EBFKHPNK_04128 5.3e-39
EBFKHPNK_04130 3.1e-68
EBFKHPNK_04133 6.1e-56
EBFKHPNK_04134 3.7e-85
EBFKHPNK_04135 6.9e-90
EBFKHPNK_04136 4.2e-91
EBFKHPNK_04138 3e-49
EBFKHPNK_04139 6.6e-52
EBFKHPNK_04142 6.4e-174 xerH A Belongs to the 'phage' integrase family
EBFKHPNK_04143 5.4e-50
EBFKHPNK_04144 1.4e-57
EBFKHPNK_04145 3.2e-82 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
EBFKHPNK_04146 1.2e-13
EBFKHPNK_04147 4.2e-38 S Domain of unknown function (DUF2479)
EBFKHPNK_04148 1.9e-48 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EBFKHPNK_04150 9.1e-18 S Phage gp6-like head-tail connector protein
EBFKHPNK_04152 9.6e-97 S Phage capsid family
EBFKHPNK_04153 5.4e-32 S Domain of unknown function (DUF4355)
EBFKHPNK_04154 1.4e-118 S Phage portal protein, SPP1 Gp6-like
EBFKHPNK_04155 4.6e-150 S TIGRFAM Phage
EBFKHPNK_04156 6.9e-89 L Resolvase, N terminal domain
EBFKHPNK_04157 3.3e-14 S Helix-turn-helix of insertion element transposase
EBFKHPNK_04159 1.2e-13 K Transcriptional regulator
EBFKHPNK_04161 2.2e-23
EBFKHPNK_04162 7.7e-11 S Phage uncharacterised protein (Phage_XkdX)
EBFKHPNK_04164 6.3e-59 S Domain of unknown function (DUF2479)
EBFKHPNK_04166 2.9e-12 yqaO S Phage-like element PBSX protein XtrA
EBFKHPNK_04170 1.3e-27
EBFKHPNK_04173 2.2e-42 dnaC L IstB-like ATP binding protein
EBFKHPNK_04174 5.4e-84 ybl78 L Conserved phage C-terminus (Phg_2220_C)
EBFKHPNK_04178 2.6e-23 K Helix-turn-helix XRE-family like proteins
EBFKHPNK_04180 2.9e-45
EBFKHPNK_04181 3.6e-67 L Arm DNA-binding domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)