ORF_ID e_value Gene_name EC_number CAZy COGs Description
NEGILFLB_00001 0.0 sfcA 1.1.1.38 C malic enzyme
NEGILFLB_00002 8.6e-160 ywkB S Membrane transport protein
NEGILFLB_00003 3.5e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NEGILFLB_00004 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEGILFLB_00005 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEGILFLB_00006 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEGILFLB_00008 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NEGILFLB_00009 6.1e-112 spoIIR S stage II sporulation protein R
NEGILFLB_00010 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NEGILFLB_00011 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEGILFLB_00012 1.7e-91 mntP P Probably functions as a manganese efflux pump
NEGILFLB_00013 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEGILFLB_00014 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NEGILFLB_00015 7.2e-95 ywlG S Belongs to the UPF0340 family
NEGILFLB_00016 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEGILFLB_00017 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEGILFLB_00018 2.5e-62 atpI S ATP synthase
NEGILFLB_00019 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NEGILFLB_00020 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEGILFLB_00021 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEGILFLB_00022 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEGILFLB_00023 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEGILFLB_00024 2.5e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEGILFLB_00025 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEGILFLB_00026 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NEGILFLB_00027 1.8e-86 ywmA
NEGILFLB_00028 1.3e-32 ywzB S membrane
NEGILFLB_00029 2.4e-133 ywmB S TATA-box binding
NEGILFLB_00030 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEGILFLB_00031 2.1e-175 spoIID D Stage II sporulation protein D
NEGILFLB_00032 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NEGILFLB_00033 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NEGILFLB_00035 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NEGILFLB_00036 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NEGILFLB_00037 3.5e-104 S response regulator aspartate phosphatase
NEGILFLB_00038 4e-84 ywmF S Peptidase M50
NEGILFLB_00039 3.8e-11 csbD K CsbD-like
NEGILFLB_00040 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NEGILFLB_00041 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NEGILFLB_00042 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NEGILFLB_00043 1.7e-64 ywnA K Transcriptional regulator
NEGILFLB_00044 4.8e-114 ywnB S NAD(P)H-binding
NEGILFLB_00045 1.3e-58 ywnC S Family of unknown function (DUF5362)
NEGILFLB_00046 5.3e-144 mta K transcriptional
NEGILFLB_00047 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEGILFLB_00048 2.2e-70 ywnF S Family of unknown function (DUF5392)
NEGILFLB_00049 2.7e-14 ywnC S Family of unknown function (DUF5362)
NEGILFLB_00050 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NEGILFLB_00051 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NEGILFLB_00052 4.4e-71 ywnJ S VanZ like family
NEGILFLB_00053 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NEGILFLB_00054 1.6e-58 nrgB K Belongs to the P(II) protein family
NEGILFLB_00055 4.3e-225 amt P Ammonium transporter
NEGILFLB_00056 7.5e-77
NEGILFLB_00057 4e-104 phzA Q Isochorismatase family
NEGILFLB_00058 9.8e-242 ywoD EGP Major facilitator superfamily
NEGILFLB_00059 7.5e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NEGILFLB_00060 1.4e-230 ywoF P Right handed beta helix region
NEGILFLB_00061 2.7e-211 ywoG EGP Major facilitator Superfamily
NEGILFLB_00062 2.1e-70 ywoH K COG1846 Transcriptional regulators
NEGILFLB_00063 3e-44 spoIIID K Stage III sporulation protein D
NEGILFLB_00064 3.5e-180 mbl D Rod shape-determining protein
NEGILFLB_00065 1.5e-125 flhO N flagellar basal body
NEGILFLB_00066 2.6e-141 flhP N flagellar basal body
NEGILFLB_00067 2e-197 S aspartate phosphatase
NEGILFLB_00068 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NEGILFLB_00069 1.3e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEGILFLB_00070 0.0 ywpD T PhoQ Sensor
NEGILFLB_00071 1.8e-174 M1-574 T Transcriptional regulatory protein, C terminal
NEGILFLB_00072 0.0 M1-568 M cell wall anchor domain
NEGILFLB_00073 5.7e-83 srtA 3.4.22.70 M Sortase family
NEGILFLB_00074 1.1e-66 ywpF S YwpF-like protein
NEGILFLB_00075 1.3e-66 ywpG
NEGILFLB_00076 3.7e-57 ssbB L Single-stranded DNA-binding protein
NEGILFLB_00077 3.4e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
NEGILFLB_00078 7.4e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NEGILFLB_00079 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NEGILFLB_00080 4.6e-307 ywqB S SWIM zinc finger
NEGILFLB_00081 1.2e-17
NEGILFLB_00082 2e-116 ywqC M biosynthesis protein
NEGILFLB_00083 2.2e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NEGILFLB_00084 4.3e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NEGILFLB_00085 5.2e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEGILFLB_00086 9.8e-154 ywqG S Domain of unknown function (DUF1963)
NEGILFLB_00087 9.7e-23 S Domain of unknown function (DUF5082)
NEGILFLB_00088 1.3e-38 ywqI S Family of unknown function (DUF5344)
NEGILFLB_00089 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
NEGILFLB_00090 1.7e-52 S MORN repeat variant
NEGILFLB_00091 4.3e-132 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NEGILFLB_00093 1.3e-88 ywrA P COG2059 Chromate transport protein ChrA
NEGILFLB_00094 1.2e-103 ywrB P Chromate transporter
NEGILFLB_00095 1e-81 ywrC K Transcriptional regulator
NEGILFLB_00096 2.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NEGILFLB_00097 2.5e-53 S Domain of unknown function (DUF4181)
NEGILFLB_00098 6.9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NEGILFLB_00099 1.3e-12
NEGILFLB_00100 6.2e-207 cotH M Spore Coat
NEGILFLB_00101 4.2e-124 cotB
NEGILFLB_00102 1e-122 ywrJ
NEGILFLB_00103 3.9e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NEGILFLB_00104 1.1e-169 alsR K LysR substrate binding domain
NEGILFLB_00105 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NEGILFLB_00106 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NEGILFLB_00107 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NEGILFLB_00108 8e-48 ywsA S Protein of unknown function (DUF3892)
NEGILFLB_00109 2.5e-92 batE T Sh3 type 3 domain protein
NEGILFLB_00110 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NEGILFLB_00111 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NEGILFLB_00112 8.1e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NEGILFLB_00113 5.3e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NEGILFLB_00114 6.1e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEGILFLB_00115 9.3e-178 rbsR K transcriptional
NEGILFLB_00116 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NEGILFLB_00117 8.6e-70 pgsC S biosynthesis protein
NEGILFLB_00118 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NEGILFLB_00119 3.6e-21 ywtC
NEGILFLB_00120 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NEGILFLB_00121 5.5e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NEGILFLB_00122 4.2e-170 ywtF K Transcriptional regulator
NEGILFLB_00123 1.2e-247 ywtG EGP Major facilitator Superfamily
NEGILFLB_00124 9.3e-206 gerAC S Spore germination protein
NEGILFLB_00125 4e-193 gerBB E Spore germination protein
NEGILFLB_00126 3.1e-262 gerBA EG Spore germination protein
NEGILFLB_00127 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NEGILFLB_00128 5.7e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEGILFLB_00129 2.4e-127 M Glycosyl transferase group 1 protein
NEGILFLB_00130 9.5e-159 wbmJ M Glycosyl transferases group 1
NEGILFLB_00132 1.8e-126 M DUF based on E. rectale Gene description (DUF3880)
NEGILFLB_00133 3.9e-160 wecC 1.1.1.336 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEGILFLB_00134 3.5e-129 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEGILFLB_00135 5.6e-54 3.4.11.5 S alpha beta
NEGILFLB_00136 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEGILFLB_00137 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEGILFLB_00138 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NEGILFLB_00139 2e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NEGILFLB_00140 9.2e-96 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NEGILFLB_00141 5.4e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NEGILFLB_00142 1.1e-52 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NEGILFLB_00143 1.2e-133 tagG GM Transport permease protein
NEGILFLB_00144 2.4e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NEGILFLB_00145 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NEGILFLB_00146 5.3e-119 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NEGILFLB_00148 2.2e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEGILFLB_00149 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NEGILFLB_00150 7.3e-36
NEGILFLB_00151 2.8e-48 lytB 3.5.1.28 D Stage II sporulation protein
NEGILFLB_00152 1.4e-265 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NEGILFLB_00153 1e-111 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NEGILFLB_00154 1.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEGILFLB_00155 6.9e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NEGILFLB_00156 9e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEGILFLB_00157 3.7e-263 tuaE M Teichuronic acid biosynthesis protein
NEGILFLB_00158 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
NEGILFLB_00159 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NEGILFLB_00160 1.6e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NEGILFLB_00161 4.5e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NEGILFLB_00162 6e-163 yvhJ K Transcriptional regulator
NEGILFLB_00163 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NEGILFLB_00164 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NEGILFLB_00165 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEGILFLB_00166 4.8e-154 degV S protein conserved in bacteria
NEGILFLB_00167 7.6e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NEGILFLB_00168 3.7e-45 comFB S Late competence development protein ComFB
NEGILFLB_00169 4.7e-126 comFC S Phosphoribosyl transferase domain
NEGILFLB_00170 7e-74 yvyF S flagellar protein
NEGILFLB_00171 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
NEGILFLB_00172 9.2e-78 flgN NOU FlgN protein
NEGILFLB_00173 2.7e-264 flgK N flagellar hook-associated protein
NEGILFLB_00174 1.3e-154 flgL N Belongs to the bacterial flagellin family
NEGILFLB_00175 1.3e-49 yviE
NEGILFLB_00176 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NEGILFLB_00177 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NEGILFLB_00178 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NEGILFLB_00179 1.2e-55 flaG N flagellar protein FlaG
NEGILFLB_00180 2.6e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NEGILFLB_00181 2.9e-69 fliS N flagellar protein FliS
NEGILFLB_00182 1.9e-08 fliT S bacterial-type flagellum organization
NEGILFLB_00183 1.8e-65
NEGILFLB_00184 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEGILFLB_00185 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEGILFLB_00186 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEGILFLB_00187 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NEGILFLB_00188 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
NEGILFLB_00189 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NEGILFLB_00190 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NEGILFLB_00191 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NEGILFLB_00192 5.3e-56 swrA S Swarming motility protein
NEGILFLB_00193 9.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NEGILFLB_00194 2.8e-225 yvkA EGP Major facilitator Superfamily
NEGILFLB_00195 3.5e-100 yvkB K Transcriptional regulator
NEGILFLB_00196 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NEGILFLB_00197 1.2e-30 csbA S protein conserved in bacteria
NEGILFLB_00198 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEGILFLB_00199 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEGILFLB_00200 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NEGILFLB_00201 5.7e-33 yvkN
NEGILFLB_00202 4e-48 yvlA
NEGILFLB_00203 2.4e-166 yvlB S Putative adhesin
NEGILFLB_00204 2.6e-26 pspB KT PspC domain
NEGILFLB_00205 1.2e-50 yvlD S Membrane
NEGILFLB_00206 2.7e-203 yvmA EGP Major facilitator Superfamily
NEGILFLB_00207 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_00208 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NEGILFLB_00209 8.8e-226 cypX 1.14.15.13 C Cytochrome P450
NEGILFLB_00210 9.5e-72 adcR K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_00211 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NEGILFLB_00212 3.6e-134 yvoA K transcriptional
NEGILFLB_00213 3.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEGILFLB_00214 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEGILFLB_00215 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NEGILFLB_00216 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEGILFLB_00217 8.1e-163 yvoD P COG0370 Fe2 transport system protein B
NEGILFLB_00218 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NEGILFLB_00219 2.8e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NEGILFLB_00220 4.8e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NEGILFLB_00221 1e-139 yvpB NU protein conserved in bacteria
NEGILFLB_00222 2.6e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NEGILFLB_00223 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NEGILFLB_00224 2e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEGILFLB_00225 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NEGILFLB_00226 2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEGILFLB_00227 6.7e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NEGILFLB_00228 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEGILFLB_00229 9.8e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NEGILFLB_00230 1.2e-76
NEGILFLB_00231 4.5e-253
NEGILFLB_00233 0.0 msbA2 3.6.3.44 V ABC transporter
NEGILFLB_00234 7.6e-277 S COG0457 FOG TPR repeat
NEGILFLB_00235 2.3e-97 usp CBM50 M protein conserved in bacteria
NEGILFLB_00236 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEGILFLB_00237 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NEGILFLB_00238 1.7e-165 rapZ S Displays ATPase and GTPase activities
NEGILFLB_00239 2.8e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NEGILFLB_00240 1.4e-170 whiA K May be required for sporulation
NEGILFLB_00241 1.6e-36 crh G Phosphocarrier protein Chr
NEGILFLB_00242 2.2e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NEGILFLB_00243 9.7e-32
NEGILFLB_00244 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_00245 2.7e-194 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NEGILFLB_00246 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NEGILFLB_00247 0.0 yxdM V ABC transporter (permease)
NEGILFLB_00248 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEGILFLB_00249 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NEGILFLB_00250 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NEGILFLB_00251 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NEGILFLB_00252 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NEGILFLB_00253 8.8e-173 yvdE K Transcriptional regulator
NEGILFLB_00254 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NEGILFLB_00255 4.8e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NEGILFLB_00256 3.8e-243 malC P COG1175 ABC-type sugar transport systems, permease components
NEGILFLB_00257 6.6e-148 malD P transport
NEGILFLB_00258 3.1e-156 malA S Protein of unknown function (DUF1189)
NEGILFLB_00259 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NEGILFLB_00260 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NEGILFLB_00261 4.5e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NEGILFLB_00262 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEGILFLB_00264 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
NEGILFLB_00265 4.1e-50 sugE P Small Multidrug Resistance protein
NEGILFLB_00266 2.8e-49 ykkC P Small Multidrug Resistance protein
NEGILFLB_00267 7e-104 yvdT K Transcriptional regulator
NEGILFLB_00268 1.8e-295 yveA E amino acid
NEGILFLB_00269 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NEGILFLB_00270 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NEGILFLB_00271 3.8e-262 pbpE V Beta-lactamase
NEGILFLB_00272 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NEGILFLB_00273 9.3e-72 MA20_18690 S Protein of unknown function (DUF3237)
NEGILFLB_00274 4.6e-93 padC Q Phenolic acid decarboxylase
NEGILFLB_00276 7e-286 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NEGILFLB_00277 6.3e-76 slr K transcriptional
NEGILFLB_00278 8.9e-122 ywqC M biosynthesis protein
NEGILFLB_00279 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NEGILFLB_00280 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NEGILFLB_00281 1.2e-219 epsD GT4 M Glycosyl transferase 4-like
NEGILFLB_00282 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NEGILFLB_00283 3.7e-218 epsF GT4 M Glycosyl transferases group 1
NEGILFLB_00284 7e-206 epsG S EpsG family
NEGILFLB_00285 3.4e-194 epsH GT2 S Glycosyltransferase like family 2
NEGILFLB_00286 9.2e-203 epsI GM pyruvyl transferase
NEGILFLB_00287 2.6e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NEGILFLB_00288 4.1e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEGILFLB_00289 5.9e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NEGILFLB_00290 4.8e-53 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NEGILFLB_00291 2.4e-217 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NEGILFLB_00292 1.3e-184 yvfF GM Exopolysaccharide biosynthesis protein
NEGILFLB_00293 1e-31 yvfG S YvfG protein
NEGILFLB_00294 3.3e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NEGILFLB_00295 9.7e-308 yvfH C L-lactate permease
NEGILFLB_00296 2.3e-112 yvfI K COG2186 Transcriptional regulators
NEGILFLB_00297 4e-184 lacR K Transcriptional regulator
NEGILFLB_00298 2e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
NEGILFLB_00299 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
NEGILFLB_00300 7.2e-150 ganQ P transport
NEGILFLB_00301 0.0 lacA 3.2.1.23 G beta-galactosidase
NEGILFLB_00302 6.4e-251 galA 3.2.1.89 G arabinogalactan
NEGILFLB_00303 1.5e-198 rsbU 3.1.3.3 T response regulator
NEGILFLB_00304 4.4e-157 rsbQ S Alpha/beta hydrolase family
NEGILFLB_00306 5.4e-156 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NEGILFLB_00307 2.1e-169 desK 2.7.13.3 T Histidine kinase
NEGILFLB_00308 2.2e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEGILFLB_00309 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NEGILFLB_00310 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NEGILFLB_00311 1.1e-130 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NEGILFLB_00312 4.1e-184 yvbX S Glycosyl hydrolase
NEGILFLB_00313 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NEGILFLB_00314 7.2e-156 yvbV EG EamA-like transporter family
NEGILFLB_00315 3.9e-159 yvbU K Transcriptional regulator
NEGILFLB_00316 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEGILFLB_00317 5.5e-203 araR K transcriptional
NEGILFLB_00318 1.1e-251 araE EGP Major facilitator Superfamily
NEGILFLB_00319 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NEGILFLB_00320 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEGILFLB_00321 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NEGILFLB_00322 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEGILFLB_00323 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NEGILFLB_00324 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEGILFLB_00325 8.2e-166 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NEGILFLB_00326 1.3e-217 1.1.1.136 M UDP binding domain
NEGILFLB_00327 5.7e-187 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NEGILFLB_00328 2.1e-147 5.1.3.2 M GDP-mannose 4,6 dehydratase
NEGILFLB_00329 2.1e-158 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NEGILFLB_00330 1.5e-114 M Protein involved in cellulose biosynthesis
NEGILFLB_00331 6.4e-123 C WbqC-like protein family
NEGILFLB_00332 2.3e-114 S GlcNAc-PI de-N-acetylase
NEGILFLB_00333 7.5e-153
NEGILFLB_00334 4.6e-174 EGP Major facilitator Superfamily
NEGILFLB_00335 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
NEGILFLB_00336 0.0 tcaA S response to antibiotic
NEGILFLB_00337 6.8e-122 exoY M Membrane
NEGILFLB_00338 1.9e-112 yvbH S YvbH-like oligomerisation region
NEGILFLB_00339 9.2e-102 yvbG U UPF0056 membrane protein
NEGILFLB_00340 3.5e-97 yvbF K Belongs to the GbsR family
NEGILFLB_00341 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NEGILFLB_00342 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NEGILFLB_00343 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEGILFLB_00344 1.6e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NEGILFLB_00345 3.3e-60 yvbF K Belongs to the GbsR family
NEGILFLB_00346 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NEGILFLB_00347 1.2e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NEGILFLB_00348 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEGILFLB_00349 4.7e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NEGILFLB_00350 7e-195 spaB S Lantibiotic dehydratase, C terminus
NEGILFLB_00351 1.3e-156 spaT V ABC transporter
NEGILFLB_00352 2.4e-96 spaC2 V PFAM Lanthionine synthetase
NEGILFLB_00353 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
NEGILFLB_00355 4.2e-103 mutF V ABC transporter, ATP-binding protein
NEGILFLB_00356 1.5e-87 spaE S ABC-2 family transporter protein
NEGILFLB_00357 1.7e-81 mutG S ABC-2 family transporter protein
NEGILFLB_00358 2.5e-105 K Transcriptional regulatory protein, C terminal
NEGILFLB_00359 2.3e-153 T His Kinase A (phosphoacceptor) domain
NEGILFLB_00360 3.2e-218 NT chemotaxis protein
NEGILFLB_00361 2.2e-54 yodB K transcriptional
NEGILFLB_00362 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
NEGILFLB_00363 1.2e-68 K transcriptional
NEGILFLB_00364 9.8e-36 yvzC K Transcriptional
NEGILFLB_00365 7.7e-151 yvaM S Serine aminopeptidase, S33
NEGILFLB_00366 2.4e-23 secG U Preprotein translocase subunit SecG
NEGILFLB_00367 5.6e-143 est 3.1.1.1 S Carboxylesterase
NEGILFLB_00368 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEGILFLB_00369 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NEGILFLB_00371 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_00372 3.3e-98 K Bacterial regulatory proteins, tetR family
NEGILFLB_00373 4.5e-53 yvaE P Small Multidrug Resistance protein
NEGILFLB_00374 5.7e-73 yvaD S Family of unknown function (DUF5360)
NEGILFLB_00375 0.0 yvaC S Fusaric acid resistance protein-like
NEGILFLB_00376 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEGILFLB_00377 7.6e-194 yvaA 1.1.1.371 S Oxidoreductase
NEGILFLB_00378 2.2e-48 csoR S transcriptional
NEGILFLB_00379 5.9e-29 copZ P Copper resistance protein CopZ
NEGILFLB_00380 0.0 copA 3.6.3.54 P P-type ATPase
NEGILFLB_00381 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NEGILFLB_00382 6.1e-104 bdbD O Thioredoxin
NEGILFLB_00383 2.9e-72 bdbC O Required for disulfide bond formation in some proteins
NEGILFLB_00384 1.6e-106 yvgT S membrane
NEGILFLB_00386 0.0 helD 3.6.4.12 L DNA helicase
NEGILFLB_00387 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NEGILFLB_00388 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NEGILFLB_00389 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NEGILFLB_00390 5.4e-86 yvgO
NEGILFLB_00391 1.1e-155 yvgN S reductase
NEGILFLB_00392 1.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NEGILFLB_00393 6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NEGILFLB_00394 7e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NEGILFLB_00395 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NEGILFLB_00396 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NEGILFLB_00397 6.5e-16 S Small spore protein J (Spore_SspJ)
NEGILFLB_00398 1.4e-235 yvsH E Arginine ornithine antiporter
NEGILFLB_00399 7.6e-177 fhuD P ABC transporter
NEGILFLB_00400 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_00401 1.3e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_00402 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NEGILFLB_00403 4.8e-176 M Efflux transporter rnd family, mfp subunit
NEGILFLB_00404 7.9e-123 macB V ABC transporter, ATP-binding protein
NEGILFLB_00405 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NEGILFLB_00406 1.3e-64 yvrL S Regulatory protein YrvL
NEGILFLB_00407 1.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
NEGILFLB_00408 2.4e-19 S YvrJ protein family
NEGILFLB_00409 1.9e-98 yvrI K RNA polymerase
NEGILFLB_00410 3.6e-22
NEGILFLB_00411 1.1e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_00412 0.0 T PhoQ Sensor
NEGILFLB_00413 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NEGILFLB_00414 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_00415 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NEGILFLB_00416 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_00417 1.1e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NEGILFLB_00418 5.5e-101 yvqK 2.5.1.17 S Adenosyltransferase
NEGILFLB_00419 7e-226 yvqJ EGP Major facilitator Superfamily
NEGILFLB_00420 5.6e-62 liaI S membrane
NEGILFLB_00421 8.1e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NEGILFLB_00422 6e-128 liaG S Putative adhesin
NEGILFLB_00423 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NEGILFLB_00424 4.6e-186 vraS 2.7.13.3 T Histidine kinase
NEGILFLB_00425 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEGILFLB_00426 2.9e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
NEGILFLB_00427 3.8e-196 gerAB E Spore germination protein
NEGILFLB_00428 1.4e-246 gerAA EG Spore germination protein
NEGILFLB_00429 3.9e-24 S Protein of unknown function (DUF3970)
NEGILFLB_00430 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NEGILFLB_00431 4.3e-158 yuxN K Transcriptional regulator
NEGILFLB_00432 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NEGILFLB_00433 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_00434 6.2e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NEGILFLB_00435 1.8e-78 dps P Ferritin-like domain
NEGILFLB_00436 8.9e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEGILFLB_00437 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NEGILFLB_00439 4.8e-165 S Alpha/beta hydrolase family
NEGILFLB_00440 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEGILFLB_00441 2.7e-85 ybfM S SNARE associated Golgi protein
NEGILFLB_00442 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NEGILFLB_00443 4.6e-45 ybfN
NEGILFLB_00444 5.6e-250 S Erythromycin esterase
NEGILFLB_00445 1.9e-191 yceA S Belongs to the UPF0176 family
NEGILFLB_00446 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEGILFLB_00447 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NEGILFLB_00448 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEGILFLB_00449 1.9e-127 K UTRA
NEGILFLB_00451 4.5e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NEGILFLB_00452 4.4e-261 mmuP E amino acid
NEGILFLB_00453 1.4e-178 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NEGILFLB_00454 2.1e-255 agcS E Sodium alanine symporter
NEGILFLB_00455 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NEGILFLB_00456 2.1e-228 phoQ 2.7.13.3 T Histidine kinase
NEGILFLB_00457 1.5e-169 glnL T Regulator
NEGILFLB_00458 1e-173 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NEGILFLB_00459 2.2e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEGILFLB_00460 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NEGILFLB_00461 4.7e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NEGILFLB_00462 2.1e-123 ycbG K FCD
NEGILFLB_00463 1.6e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
NEGILFLB_00464 3.3e-177 ycbJ S Macrolide 2'-phosphotransferase
NEGILFLB_00465 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NEGILFLB_00466 3.8e-168 eamA1 EG spore germination
NEGILFLB_00467 1.1e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_00468 9.9e-169 T PhoQ Sensor
NEGILFLB_00469 5.5e-164 ycbN V ABC transporter, ATP-binding protein
NEGILFLB_00470 2.5e-113 S ABC-2 family transporter protein
NEGILFLB_00471 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NEGILFLB_00472 2.2e-78 sleB 3.5.1.28 M Cell wall
NEGILFLB_00473 1.6e-134 ycbR T vWA found in TerF C terminus
NEGILFLB_00474 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NEGILFLB_00475 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NEGILFLB_00476 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NEGILFLB_00477 1.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEGILFLB_00478 6.6e-204 ycbU E Selenocysteine lyase
NEGILFLB_00479 7.9e-226 lmrB EGP the major facilitator superfamily
NEGILFLB_00480 3.5e-100 yxaF K Transcriptional regulator
NEGILFLB_00481 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NEGILFLB_00482 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NEGILFLB_00483 4.5e-59 S RDD family
NEGILFLB_00484 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
NEGILFLB_00485 2.2e-155 2.7.13.3 T GHKL domain
NEGILFLB_00486 1.2e-126 lytR_2 T LytTr DNA-binding domain
NEGILFLB_00487 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NEGILFLB_00488 1.2e-200 natB CP ABC-2 family transporter protein
NEGILFLB_00489 1.1e-172 yccK C Aldo keto reductase
NEGILFLB_00490 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NEGILFLB_00491 1.7e-268 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_00492 1.3e-258 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_00493 5.3e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
NEGILFLB_00494 3e-172 S response regulator aspartate phosphatase
NEGILFLB_00495 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
NEGILFLB_00496 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NEGILFLB_00497 1.1e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
NEGILFLB_00498 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NEGILFLB_00499 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NEGILFLB_00500 1.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEGILFLB_00501 1.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NEGILFLB_00502 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NEGILFLB_00503 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NEGILFLB_00504 6.3e-137 terC P Protein of unknown function (DUF475)
NEGILFLB_00505 0.0 yceG S Putative component of 'biosynthetic module'
NEGILFLB_00506 2e-192 yceH P Belongs to the TelA family
NEGILFLB_00507 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
NEGILFLB_00509 2.6e-237 mmr U Major Facilitator Superfamily
NEGILFLB_00510 5.3e-78 yffB K Transcriptional regulator
NEGILFLB_00511 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NEGILFLB_00512 2.1e-254 ywfO S COG1078 HD superfamily phosphohydrolases
NEGILFLB_00513 3.1e-36 ywzC S Belongs to the UPF0741 family
NEGILFLB_00514 1e-110 rsfA_1
NEGILFLB_00515 7.5e-158 ywfM EG EamA-like transporter family
NEGILFLB_00516 3.3e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NEGILFLB_00517 1.1e-156 cysL K Transcriptional regulator
NEGILFLB_00518 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NEGILFLB_00519 1.1e-146 ywfI C May function as heme-dependent peroxidase
NEGILFLB_00520 1.9e-136 IQ Enoyl-(Acyl carrier protein) reductase
NEGILFLB_00521 5.6e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
NEGILFLB_00522 7.3e-209 bacE EGP Major facilitator Superfamily
NEGILFLB_00523 1.5e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NEGILFLB_00524 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_00525 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NEGILFLB_00526 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NEGILFLB_00527 6.6e-205 ywfA EGP Major facilitator Superfamily
NEGILFLB_00528 1.3e-260 lysP E amino acid
NEGILFLB_00529 0.0 rocB E arginine degradation protein
NEGILFLB_00530 1.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NEGILFLB_00531 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NEGILFLB_00532 9.8e-77
NEGILFLB_00533 6.7e-86 spsL 5.1.3.13 M Spore Coat
NEGILFLB_00534 1.9e-155 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NEGILFLB_00535 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEGILFLB_00536 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NEGILFLB_00537 1.4e-187 spsG M Spore Coat
NEGILFLB_00538 1e-128 spsF M Spore Coat
NEGILFLB_00539 1.2e-213 spsE 2.5.1.56 M acid synthase
NEGILFLB_00540 1.5e-163 spsD 2.3.1.210 K Spore Coat
NEGILFLB_00541 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
NEGILFLB_00542 4.7e-268 spsB M Capsule polysaccharide biosynthesis protein
NEGILFLB_00543 4.5e-143 spsA M Spore Coat
NEGILFLB_00544 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NEGILFLB_00545 4.3e-59 ywdK S small membrane protein
NEGILFLB_00546 1.1e-237 ywdJ F Xanthine uracil
NEGILFLB_00547 5e-48 ywdI S Family of unknown function (DUF5327)
NEGILFLB_00548 1.6e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NEGILFLB_00549 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEGILFLB_00550 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
NEGILFLB_00552 1.4e-113 ywdD
NEGILFLB_00553 1.3e-57 pex K Transcriptional regulator PadR-like family
NEGILFLB_00554 3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NEGILFLB_00555 2e-28 ywdA
NEGILFLB_00556 5.8e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NEGILFLB_00557 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NEGILFLB_00558 6.7e-139 focA P Formate/nitrite transporter
NEGILFLB_00559 7e-150 sacT K transcriptional antiterminator
NEGILFLB_00561 0.0 vpr O Belongs to the peptidase S8 family
NEGILFLB_00562 1.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEGILFLB_00563 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NEGILFLB_00564 1.1e-188 rodA D Belongs to the SEDS family
NEGILFLB_00565 4.1e-201 S Acetyltransferase
NEGILFLB_00566 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NEGILFLB_00567 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NEGILFLB_00568 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NEGILFLB_00569 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NEGILFLB_00570 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NEGILFLB_00571 1e-35 ywzA S membrane
NEGILFLB_00572 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NEGILFLB_00573 4.9e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NEGILFLB_00574 1.4e-58 gtcA S GtrA-like protein
NEGILFLB_00575 1.1e-121 ywcC K transcriptional regulator
NEGILFLB_00577 1.7e-48 ywcB S Protein of unknown function, DUF485
NEGILFLB_00578 3.1e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEGILFLB_00579 6.9e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NEGILFLB_00580 4.9e-224 ywbN P Dyp-type peroxidase family protein
NEGILFLB_00581 2.6e-187 ycdO P periplasmic lipoprotein involved in iron transport
NEGILFLB_00582 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
NEGILFLB_00583 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEGILFLB_00584 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEGILFLB_00585 4.3e-153 ywbI K Transcriptional regulator
NEGILFLB_00586 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NEGILFLB_00587 2.3e-111 ywbG M effector of murein hydrolase
NEGILFLB_00588 1.9e-209 ywbF EGP Major facilitator Superfamily
NEGILFLB_00589 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NEGILFLB_00590 7e-220 ywbD 2.1.1.191 J Methyltransferase
NEGILFLB_00591 4.4e-67 ywbC 4.4.1.5 E glyoxalase
NEGILFLB_00592 2e-123 ywbB S Protein of unknown function (DUF2711)
NEGILFLB_00593 7.1e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEGILFLB_00594 4e-273 epr 3.4.21.62 O Belongs to the peptidase S8 family
NEGILFLB_00595 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NEGILFLB_00596 4e-153 sacY K transcriptional antiterminator
NEGILFLB_00597 7e-169 gspA M General stress
NEGILFLB_00598 1.5e-124 ywaF S Integral membrane protein
NEGILFLB_00599 7.1e-84 ywaE K Transcriptional regulator
NEGILFLB_00600 1.4e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEGILFLB_00601 5.7e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NEGILFLB_00602 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NEGILFLB_00603 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NEGILFLB_00604 5e-14 S D-Ala-teichoic acid biosynthesis protein
NEGILFLB_00605 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_00606 3.6e-232 dltB M membrane protein involved in D-alanine export
NEGILFLB_00607 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_00608 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NEGILFLB_00609 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_00610 5.9e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NEGILFLB_00611 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NEGILFLB_00612 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NEGILFLB_00613 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEGILFLB_00614 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NEGILFLB_00615 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NEGILFLB_00616 1.1e-19 yxzF
NEGILFLB_00617 1.1e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NEGILFLB_00618 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NEGILFLB_00619 3.8e-213 yxlH EGP Major facilitator Superfamily
NEGILFLB_00620 3.4e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NEGILFLB_00621 4.4e-166 yxlF V ABC transporter, ATP-binding protein
NEGILFLB_00622 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
NEGILFLB_00623 2.2e-28
NEGILFLB_00624 8.1e-46 yxlC S Family of unknown function (DUF5345)
NEGILFLB_00625 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_00626 1.1e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NEGILFLB_00627 1.1e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEGILFLB_00628 0.0 cydD V ATP-binding protein
NEGILFLB_00629 6.1e-310 cydD V ATP-binding
NEGILFLB_00630 3.8e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NEGILFLB_00631 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NEGILFLB_00632 2.1e-228 cimH C COG3493 Na citrate symporter
NEGILFLB_00633 6.7e-309 3.4.24.84 O Peptidase family M48
NEGILFLB_00635 5.6e-155 yxkH G Polysaccharide deacetylase
NEGILFLB_00636 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NEGILFLB_00637 4.1e-164 lrp QT PucR C-terminal helix-turn-helix domain
NEGILFLB_00638 2.2e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEGILFLB_00639 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEGILFLB_00640 1.3e-74 yxkC S Domain of unknown function (DUF4352)
NEGILFLB_00641 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NEGILFLB_00642 5.9e-77 S Protein of unknown function (DUF1453)
NEGILFLB_00643 1.1e-178 yxjM T Signal transduction histidine kinase
NEGILFLB_00644 4.6e-112 K helix_turn_helix, Lux Regulon
NEGILFLB_00645 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NEGILFLB_00648 3.2e-86 yxjI S LURP-one-related
NEGILFLB_00649 9.7e-219 yxjG 2.1.1.14 E Methionine synthase
NEGILFLB_00650 3.1e-217 yxjG 2.1.1.14 E Methionine synthase
NEGILFLB_00651 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NEGILFLB_00652 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NEGILFLB_00653 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NEGILFLB_00654 1.7e-252 yxjC EG COG2610 H gluconate symporter and related permeases
NEGILFLB_00655 1.4e-153 rlmA 2.1.1.187 Q Methyltransferase domain
NEGILFLB_00657 1e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NEGILFLB_00658 1.3e-93 T Domain of unknown function (DUF4163)
NEGILFLB_00659 3e-47 yxiS
NEGILFLB_00660 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NEGILFLB_00661 6.6e-224 citH C Citrate transporter
NEGILFLB_00662 1.1e-143 exoK GH16 M licheninase activity
NEGILFLB_00663 8.3e-151 licT K transcriptional antiterminator
NEGILFLB_00664 6.6e-114
NEGILFLB_00665 2.3e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
NEGILFLB_00666 8.7e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NEGILFLB_00667 2.3e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NEGILFLB_00668 1.4e-53 padR K Transcriptional regulator PadR-like family
NEGILFLB_00669 2.9e-61 S Protein of unknown function (DUF2812)
NEGILFLB_00672 3.5e-43 yxiJ S YxiJ-like protein
NEGILFLB_00675 4.4e-34
NEGILFLB_00676 2.3e-84 yxiI S Protein of unknown function (DUF2716)
NEGILFLB_00677 1.5e-136
NEGILFLB_00678 8.3e-13 yxiG
NEGILFLB_00679 7.6e-16 yxiG
NEGILFLB_00680 0.0 wapA M COG3209 Rhs family protein
NEGILFLB_00681 3.1e-162 yxxF EG EamA-like transporter family
NEGILFLB_00682 1.1e-72 yxiE T Belongs to the universal stress protein A family
NEGILFLB_00683 4.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEGILFLB_00684 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NEGILFLB_00685 3.3e-32
NEGILFLB_00686 9.4e-138 S nuclease activity
NEGILFLB_00687 1.4e-38 yxiC S Family of unknown function (DUF5344)
NEGILFLB_00688 2.3e-20 S Domain of unknown function (DUF5082)
NEGILFLB_00689 0.0 L HKD family nuclease
NEGILFLB_00691 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NEGILFLB_00692 0.0 dhbF IQ polyketide synthase
NEGILFLB_00693 0.0 pks13 HQ Beta-ketoacyl synthase
NEGILFLB_00694 4.1e-231 cypA C Cytochrome P450
NEGILFLB_00695 4.4e-61 ymzB
NEGILFLB_00696 1.2e-160 ymaE S Metallo-beta-lactamase superfamily
NEGILFLB_00697 3e-251 aprX O Belongs to the peptidase S8 family
NEGILFLB_00698 1.9e-07 K Transcriptional regulator
NEGILFLB_00699 2.1e-126 ymaC S Replication protein
NEGILFLB_00700 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
NEGILFLB_00701 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NEGILFLB_00702 5.4e-50 ebrA P Small Multidrug Resistance protein
NEGILFLB_00704 2.1e-46 ymaF S YmaF family
NEGILFLB_00705 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEGILFLB_00706 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NEGILFLB_00707 8.2e-23
NEGILFLB_00708 4.5e-22 ymzA
NEGILFLB_00709 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NEGILFLB_00710 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEGILFLB_00711 5.9e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEGILFLB_00712 7.6e-109 ymaB
NEGILFLB_00713 1.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NEGILFLB_00714 1.7e-176 spoVK O stage V sporulation protein K
NEGILFLB_00715 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEGILFLB_00716 6.3e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NEGILFLB_00717 4.3e-68 glnR K transcriptional
NEGILFLB_00718 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
NEGILFLB_00719 1.3e-38 L Arm DNA-binding domain
NEGILFLB_00720 1.2e-82 dnaB 3.6.4.12 L replicative DNA helicase
NEGILFLB_00721 1.7e-21
NEGILFLB_00723 7.1e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
NEGILFLB_00724 3.4e-31 csfB S Inhibitor of sigma-G Gin
NEGILFLB_00725 5.8e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NEGILFLB_00726 1.1e-201 yaaN P Belongs to the TelA family
NEGILFLB_00727 3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NEGILFLB_00728 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEGILFLB_00729 2.2e-54 yaaQ S protein conserved in bacteria
NEGILFLB_00730 1.5e-71 yaaR S protein conserved in bacteria
NEGILFLB_00731 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NEGILFLB_00732 6.1e-146 yaaT S stage 0 sporulation protein
NEGILFLB_00733 4.8e-31 yabA L Involved in initiation control of chromosome replication
NEGILFLB_00734 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
NEGILFLB_00735 1.5e-49 yazA L endonuclease containing a URI domain
NEGILFLB_00736 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEGILFLB_00737 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NEGILFLB_00738 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEGILFLB_00739 1.2e-143 tatD L hydrolase, TatD
NEGILFLB_00740 2e-167 rpfB GH23 T protein conserved in bacteria
NEGILFLB_00741 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NEGILFLB_00742 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEGILFLB_00743 1.6e-136 yabG S peptidase
NEGILFLB_00744 7.8e-39 veg S protein conserved in bacteria
NEGILFLB_00745 8.3e-27 sspF S DNA topological change
NEGILFLB_00746 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEGILFLB_00747 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NEGILFLB_00748 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NEGILFLB_00749 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NEGILFLB_00750 4.6e-223 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEGILFLB_00751 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEGILFLB_00752 1.5e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NEGILFLB_00753 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEGILFLB_00754 2.4e-39 yabK S Peptide ABC transporter permease
NEGILFLB_00755 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEGILFLB_00756 1.5e-92 spoVT K stage V sporulation protein
NEGILFLB_00757 1.7e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEGILFLB_00758 6.2e-242 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NEGILFLB_00759 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NEGILFLB_00760 1.5e-49 yabP S Sporulation protein YabP
NEGILFLB_00761 9.5e-107 yabQ S spore cortex biosynthesis protein
NEGILFLB_00762 1.1e-44 divIC D Septum formation initiator
NEGILFLB_00763 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NEGILFLB_00765 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NEGILFLB_00766 1.4e-64 eag
NEGILFLB_00767 6.4e-09 S Spo0E like sporulation regulatory protein
NEGILFLB_00768 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NEGILFLB_00769 2.9e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NEGILFLB_00770 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NEGILFLB_00771 2.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NEGILFLB_00772 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NEGILFLB_00773 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
NEGILFLB_00774 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NEGILFLB_00775 1.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NEGILFLB_00776 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NEGILFLB_00778 2e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NEGILFLB_00779 0.0 kinE 2.7.13.3 T Histidine kinase
NEGILFLB_00780 3.2e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NEGILFLB_00781 4.1e-18 ykzE
NEGILFLB_00782 1.2e-10 ydfR S Protein of unknown function (DUF421)
NEGILFLB_00783 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NEGILFLB_00784 1.7e-154 htpX O Belongs to the peptidase M48B family
NEGILFLB_00785 3.3e-124 ykrK S Domain of unknown function (DUF1836)
NEGILFLB_00786 1.9e-26 sspD S small acid-soluble spore protein
NEGILFLB_00787 1.8e-111 rsgI S Anti-sigma factor N-terminus
NEGILFLB_00788 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEGILFLB_00789 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NEGILFLB_00790 2.7e-109 ykoX S membrane-associated protein
NEGILFLB_00791 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NEGILFLB_00792 1.1e-158 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NEGILFLB_00793 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NEGILFLB_00794 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NEGILFLB_00795 0.0 ykoS
NEGILFLB_00796 1e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NEGILFLB_00797 2.7e-97 ykoP G polysaccharide deacetylase
NEGILFLB_00798 1.2e-218 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NEGILFLB_00799 1.3e-81 mhqR K transcriptional
NEGILFLB_00800 6.9e-26 ykoL
NEGILFLB_00801 5.9e-18
NEGILFLB_00802 1.4e-53 tnrA K transcriptional
NEGILFLB_00803 2.2e-222 mgtE P Acts as a magnesium transporter
NEGILFLB_00806 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
NEGILFLB_00807 1.1e-111 ykoI S Peptidase propeptide and YPEB domain
NEGILFLB_00808 1e-243 ykoH 2.7.13.3 T Histidine kinase
NEGILFLB_00809 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_00810 5.7e-109 ykoF S YKOF-related Family
NEGILFLB_00811 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NEGILFLB_00812 1.3e-304 P ABC transporter, ATP-binding protein
NEGILFLB_00813 2e-135 ykoC P Cobalt transport protein
NEGILFLB_00814 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NEGILFLB_00815 1.7e-176 isp O Belongs to the peptidase S8 family
NEGILFLB_00816 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEGILFLB_00817 8.1e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NEGILFLB_00818 1.9e-71 ohrB O Organic hydroperoxide resistance protein
NEGILFLB_00819 1.7e-73 ohrR K COG1846 Transcriptional regulators
NEGILFLB_00820 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NEGILFLB_00821 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEGILFLB_00822 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEGILFLB_00823 3.3e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NEGILFLB_00824 7e-50 ykkD P Multidrug resistance protein
NEGILFLB_00825 3.5e-55 ykkC P Multidrug resistance protein
NEGILFLB_00826 3.3e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NEGILFLB_00827 8.8e-98 ykkA S Protein of unknown function (DUF664)
NEGILFLB_00828 2.7e-129 ykjA S Protein of unknown function (DUF421)
NEGILFLB_00829 1e-10
NEGILFLB_00830 2.5e-225 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NEGILFLB_00831 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NEGILFLB_00832 3.8e-151 ykgA E Amidinotransferase
NEGILFLB_00833 6.9e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
NEGILFLB_00834 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
NEGILFLB_00835 1.8e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NEGILFLB_00836 1.8e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NEGILFLB_00837 2.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NEGILFLB_00839 0.0 dppE E ABC transporter substrate-binding protein
NEGILFLB_00840 1.3e-185 dppD P Belongs to the ABC transporter superfamily
NEGILFLB_00841 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEGILFLB_00842 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEGILFLB_00843 5.1e-153 dppA E D-aminopeptidase
NEGILFLB_00844 1.2e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NEGILFLB_00845 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NEGILFLB_00847 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NEGILFLB_00848 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEGILFLB_00849 6.1e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NEGILFLB_00850 1.2e-239 steT E amino acid
NEGILFLB_00851 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NEGILFLB_00852 5.8e-175 pit P phosphate transporter
NEGILFLB_00853 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NEGILFLB_00854 6.7e-23 spoIISB S Stage II sporulation protein SB
NEGILFLB_00855 1.2e-160 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NEGILFLB_00856 9.3e-40 xhlB S SPP1 phage holin
NEGILFLB_00857 3.9e-28 xhlA S Haemolysin XhlA
NEGILFLB_00858 4.9e-14 xkdX
NEGILFLB_00860 4e-100
NEGILFLB_00861 6.7e-41
NEGILFLB_00862 6.4e-102 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NEGILFLB_00863 3.3e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NEGILFLB_00864 9e-69 xkdS S Protein of unknown function (DUF2634)
NEGILFLB_00865 2.3e-38 xkdR S Protein of unknown function (DUF2577)
NEGILFLB_00866 1.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
NEGILFLB_00867 2.7e-118 xkdP S Lysin motif
NEGILFLB_00868 1.3e-234 xkdO L Transglycosylase SLT domain
NEGILFLB_00869 1.8e-251 agcS E Sodium alanine symporter
NEGILFLB_00870 8e-135 brnQ E Component of the transport system for branched-chain amino acids
NEGILFLB_00871 9.2e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NEGILFLB_00872 1.3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NEGILFLB_00873 1e-108 yttP K Transcriptional regulator
NEGILFLB_00874 6.5e-87 ytsP 1.8.4.14 T GAF domain-containing protein
NEGILFLB_00875 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NEGILFLB_00876 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEGILFLB_00878 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEGILFLB_00879 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NEGILFLB_00880 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NEGILFLB_00881 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NEGILFLB_00882 8.9e-223 acuC BQ histone deacetylase
NEGILFLB_00883 1.4e-125 motS N Flagellar motor protein
NEGILFLB_00884 2.1e-146 motA N flagellar motor
NEGILFLB_00885 1.7e-182 ccpA K catabolite control protein A
NEGILFLB_00886 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NEGILFLB_00887 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
NEGILFLB_00888 6.6e-17 ytxH S COG4980 Gas vesicle protein
NEGILFLB_00889 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NEGILFLB_00890 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NEGILFLB_00891 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NEGILFLB_00892 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEGILFLB_00893 9.8e-149 ytpQ S Belongs to the UPF0354 family
NEGILFLB_00894 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NEGILFLB_00895 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NEGILFLB_00896 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NEGILFLB_00897 2.2e-51 ytzB S small secreted protein
NEGILFLB_00898 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NEGILFLB_00899 1.6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NEGILFLB_00900 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEGILFLB_00901 2e-45 ytzH S YtzH-like protein
NEGILFLB_00902 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NEGILFLB_00903 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NEGILFLB_00904 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NEGILFLB_00905 1.3e-165 ytlQ
NEGILFLB_00906 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NEGILFLB_00907 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NEGILFLB_00908 2.3e-270 pepV 3.5.1.18 E Dipeptidase
NEGILFLB_00909 4.6e-225 pbuO S permease
NEGILFLB_00910 2.4e-201 ythQ U Bacterial ABC transporter protein EcsB
NEGILFLB_00911 4.8e-131 ythP V ABC transporter
NEGILFLB_00912 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NEGILFLB_00913 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NEGILFLB_00914 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEGILFLB_00915 1.4e-231 ytfP S HI0933-like protein
NEGILFLB_00916 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NEGILFLB_00917 3.1e-26 yteV S Sporulation protein Cse60
NEGILFLB_00918 1.3e-114 yteU S Integral membrane protein
NEGILFLB_00919 1.2e-246 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NEGILFLB_00920 3.9e-72 yteS G transport
NEGILFLB_00921 3.6e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NEGILFLB_00922 1.6e-169 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NEGILFLB_00923 0.0 ytdP K Transcriptional regulator
NEGILFLB_00924 1.7e-287 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NEGILFLB_00925 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NEGILFLB_00926 1.4e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NEGILFLB_00927 1.5e-217 bioI 1.14.14.46 C Cytochrome P450
NEGILFLB_00928 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NEGILFLB_00929 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NEGILFLB_00930 2.5e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NEGILFLB_00931 2.7e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NEGILFLB_00932 3.8e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NEGILFLB_00933 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
NEGILFLB_00934 2.8e-188 msmR K Transcriptional regulator
NEGILFLB_00935 1.5e-244 msmE G Bacterial extracellular solute-binding protein
NEGILFLB_00936 6.2e-168 amyD P ABC transporter
NEGILFLB_00937 4.4e-144 amyC P ABC transporter (permease)
NEGILFLB_00938 4.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NEGILFLB_00939 8.1e-51 ytwF P Sulfurtransferase
NEGILFLB_00940 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEGILFLB_00942 3.3e-13 S Microvirus J protein
NEGILFLB_00943 1.4e-78 S Bacteriophage scaffolding protein D
NEGILFLB_00944 9.8e-42 S Phage protein C
NEGILFLB_00945 1.6e-301 S Bacteriophage replication gene A protein (GPA)
NEGILFLB_00946 2.7e-140 S Microvirus H protein (pilot protein)
NEGILFLB_00947 3.7e-96 S Major spike protein (G protein)
NEGILFLB_00948 2.9e-96 yrhH Q methyltransferase
NEGILFLB_00951 5.2e-142 focA P Formate nitrite
NEGILFLB_00952 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
NEGILFLB_00953 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NEGILFLB_00954 2.4e-78 yrhD S Protein of unknown function (DUF1641)
NEGILFLB_00955 4.6e-35 yrhC S YrhC-like protein
NEGILFLB_00956 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NEGILFLB_00957 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NEGILFLB_00958 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEGILFLB_00959 1.9e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NEGILFLB_00960 1e-25 yrzA S Protein of unknown function (DUF2536)
NEGILFLB_00961 7.9e-62 yrrS S Protein of unknown function (DUF1510)
NEGILFLB_00962 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NEGILFLB_00963 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEGILFLB_00964 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NEGILFLB_00965 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NEGILFLB_00966 7.3e-172 yegQ O Peptidase U32
NEGILFLB_00967 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
NEGILFLB_00968 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEGILFLB_00969 1.2e-45 yrzB S Belongs to the UPF0473 family
NEGILFLB_00970 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEGILFLB_00971 1.7e-41 yrzL S Belongs to the UPF0297 family
NEGILFLB_00972 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEGILFLB_00973 7.8e-170 yrrI S AI-2E family transporter
NEGILFLB_00974 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NEGILFLB_00975 2.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
NEGILFLB_00976 8e-109 gluC P ABC transporter
NEGILFLB_00977 7.6e-107 glnP P ABC transporter
NEGILFLB_00978 8e-08 S Protein of unknown function (DUF3918)
NEGILFLB_00979 9.8e-31 yrzR
NEGILFLB_00980 1.2e-82 yrrD S protein conserved in bacteria
NEGILFLB_00981 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEGILFLB_00982 1.4e-15 S COG0457 FOG TPR repeat
NEGILFLB_00983 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEGILFLB_00984 7.5e-211 iscS 2.8.1.7 E Cysteine desulfurase
NEGILFLB_00985 1.2e-70 cymR K Transcriptional regulator
NEGILFLB_00986 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NEGILFLB_00987 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NEGILFLB_00988 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NEGILFLB_00989 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NEGILFLB_00991 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
NEGILFLB_00992 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEGILFLB_00993 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEGILFLB_00994 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEGILFLB_00995 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NEGILFLB_00996 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NEGILFLB_00997 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NEGILFLB_00998 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NEGILFLB_00999 1.6e-48 yrzD S Post-transcriptional regulator
NEGILFLB_01000 6.9e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEGILFLB_01001 1.7e-111 yrbG S membrane
NEGILFLB_01002 2.2e-73 yrzE S Protein of unknown function (DUF3792)
NEGILFLB_01003 1.1e-38 yajC U Preprotein translocase subunit YajC
NEGILFLB_01004 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEGILFLB_01005 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEGILFLB_01006 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NEGILFLB_01007 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEGILFLB_01008 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEGILFLB_01009 4.8e-93 bofC S BofC C-terminal domain
NEGILFLB_01010 1e-251 csbX EGP Major facilitator Superfamily
NEGILFLB_01011 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NEGILFLB_01012 7.2e-118 yrzF T serine threonine protein kinase
NEGILFLB_01014 1.4e-51 S Family of unknown function (DUF5412)
NEGILFLB_01015 3.1e-262 alsT E Sodium alanine symporter
NEGILFLB_01016 7.2e-127 yebC K transcriptional regulatory protein
NEGILFLB_01017 1.3e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEGILFLB_01018 8.3e-157 safA M spore coat assembly protein SafA
NEGILFLB_01019 1.2e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NEGILFLB_01020 5.2e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NEGILFLB_01021 3.4e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NEGILFLB_01022 4.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
NEGILFLB_01023 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NEGILFLB_01024 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
NEGILFLB_01025 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NEGILFLB_01026 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEGILFLB_01027 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NEGILFLB_01028 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NEGILFLB_01029 4.1e-56 ysxB J ribosomal protein
NEGILFLB_01030 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NEGILFLB_01031 9.2e-161 spoIVFB S Stage IV sporulation protein
NEGILFLB_01032 2.5e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NEGILFLB_01033 2.8e-143 minD D Belongs to the ParA family
NEGILFLB_01034 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NEGILFLB_01035 7.1e-84 mreD M shape-determining protein
NEGILFLB_01036 1.1e-156 mreC M Involved in formation and maintenance of cell shape
NEGILFLB_01037 1.8e-184 mreB D Rod shape-determining protein MreB
NEGILFLB_01038 1.3e-125 radC E Belongs to the UPF0758 family
NEGILFLB_01039 2.8e-102 maf D septum formation protein Maf
NEGILFLB_01040 1.9e-165 spoIIB S Sporulation related domain
NEGILFLB_01041 3.1e-125 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NEGILFLB_01042 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NEGILFLB_01043 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEGILFLB_01044 1.6e-25
NEGILFLB_01045 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NEGILFLB_01046 3.3e-202 spoVID M stage VI sporulation protein D
NEGILFLB_01047 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NEGILFLB_01048 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NEGILFLB_01049 6e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NEGILFLB_01050 2.1e-171 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NEGILFLB_01051 3.6e-146 hemX O cytochrome C
NEGILFLB_01052 1.3e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NEGILFLB_01053 5.4e-89 ysxD
NEGILFLB_01054 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NEGILFLB_01055 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NEGILFLB_01056 6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NEGILFLB_01057 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEGILFLB_01058 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEGILFLB_01059 2.3e-187 ysoA H Tetratricopeptide repeat
NEGILFLB_01060 1.5e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEGILFLB_01061 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEGILFLB_01062 3.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NEGILFLB_01063 1.6e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NEGILFLB_01064 9.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEGILFLB_01065 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NEGILFLB_01066 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NEGILFLB_01068 9.6e-77 ysnE K acetyltransferase
NEGILFLB_01069 2.6e-117 ysnF S protein conserved in bacteria
NEGILFLB_01071 4.1e-92 ysnB S Phosphoesterase
NEGILFLB_01072 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEGILFLB_01073 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NEGILFLB_01074 2.9e-196 gerM S COG5401 Spore germination protein
NEGILFLB_01075 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NEGILFLB_01076 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_01077 3.3e-30 gerE K Transcriptional regulator
NEGILFLB_01078 3.2e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NEGILFLB_01079 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NEGILFLB_01080 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NEGILFLB_01081 2.4e-107 sdhC C succinate dehydrogenase
NEGILFLB_01082 1.2e-79 yslB S Protein of unknown function (DUF2507)
NEGILFLB_01083 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NEGILFLB_01084 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEGILFLB_01085 2e-52 trxA O Belongs to the thioredoxin family
NEGILFLB_01086 4.5e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NEGILFLB_01088 1.8e-176 etfA C Electron transfer flavoprotein
NEGILFLB_01089 2.2e-134 etfB C Electron transfer flavoprotein
NEGILFLB_01090 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NEGILFLB_01091 4e-99 fadR K Transcriptional regulator
NEGILFLB_01092 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NEGILFLB_01093 7.3e-68 yshE S membrane
NEGILFLB_01094 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEGILFLB_01095 0.0 polX L COG1796 DNA polymerase IV (family X)
NEGILFLB_01096 1.5e-84 cvpA S membrane protein, required for colicin V production
NEGILFLB_01097 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NEGILFLB_01098 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEGILFLB_01099 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEGILFLB_01100 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEGILFLB_01101 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEGILFLB_01102 5.8e-32 sspI S Belongs to the SspI family
NEGILFLB_01103 3.6e-202 ysfB KT regulator
NEGILFLB_01104 8.8e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
NEGILFLB_01105 3.1e-256 glcF C Glycolate oxidase
NEGILFLB_01106 3.4e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NEGILFLB_01107 0.0 cstA T Carbon starvation protein
NEGILFLB_01108 2.5e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NEGILFLB_01109 3.4e-144 araQ G transport system permease
NEGILFLB_01110 1.4e-167 araP G carbohydrate transport
NEGILFLB_01111 6.9e-253 araN G carbohydrate transport
NEGILFLB_01112 1.3e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NEGILFLB_01113 3.9e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NEGILFLB_01114 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NEGILFLB_01115 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NEGILFLB_01116 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NEGILFLB_01117 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NEGILFLB_01118 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NEGILFLB_01119 3.5e-67 ysdB S Sigma-w pathway protein YsdB
NEGILFLB_01120 7.5e-45 ysdA S Membrane
NEGILFLB_01121 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEGILFLB_01122 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NEGILFLB_01123 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEGILFLB_01125 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NEGILFLB_01126 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NEGILFLB_01127 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
NEGILFLB_01128 0.0 lytS 2.7.13.3 T Histidine kinase
NEGILFLB_01129 7.3e-149 ysaA S HAD-hyrolase-like
NEGILFLB_01130 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEGILFLB_01132 1.4e-158 ytxC S YtxC-like family
NEGILFLB_01133 4.6e-109 ytxB S SNARE associated Golgi protein
NEGILFLB_01134 3.6e-171 dnaI L Primosomal protein DnaI
NEGILFLB_01135 2.2e-265 dnaB L Membrane attachment protein
NEGILFLB_01136 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEGILFLB_01137 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NEGILFLB_01138 3.7e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEGILFLB_01139 9.9e-67 ytcD K Transcriptional regulator
NEGILFLB_01140 4.6e-203 ytbD EGP Major facilitator Superfamily
NEGILFLB_01141 4.4e-160 ytbE S reductase
NEGILFLB_01142 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEGILFLB_01143 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NEGILFLB_01144 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NEGILFLB_01145 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEGILFLB_01146 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NEGILFLB_01147 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_01148 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NEGILFLB_01149 4.1e-242 icd 1.1.1.42 C isocitrate
NEGILFLB_01150 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NEGILFLB_01151 4.7e-71 yeaL S membrane
NEGILFLB_01152 4.4e-192 ytvI S sporulation integral membrane protein YtvI
NEGILFLB_01153 1.6e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NEGILFLB_01154 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NEGILFLB_01155 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEGILFLB_01156 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NEGILFLB_01157 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEGILFLB_01158 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NEGILFLB_01159 0.0 dnaE 2.7.7.7 L DNA polymerase
NEGILFLB_01160 3.2e-56 ytrH S Sporulation protein YtrH
NEGILFLB_01161 8.2e-69 ytrI
NEGILFLB_01162 9.2e-29
NEGILFLB_01163 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NEGILFLB_01164 2.4e-47 ytpI S YtpI-like protein
NEGILFLB_01165 8e-241 ytoI K transcriptional regulator containing CBS domains
NEGILFLB_01166 1.7e-130 ytkL S Belongs to the UPF0173 family
NEGILFLB_01167 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_01169 4.4e-266 argH 4.3.2.1 E argininosuccinate lyase
NEGILFLB_01170 1.1e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEGILFLB_01171 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NEGILFLB_01172 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEGILFLB_01173 7e-165 ytxK 2.1.1.72 L DNA methylase
NEGILFLB_01174 5.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEGILFLB_01175 8.7e-70 ytfJ S Sporulation protein YtfJ
NEGILFLB_01176 3.1e-114 ytfI S Protein of unknown function (DUF2953)
NEGILFLB_01177 7.2e-86 yteJ S RDD family
NEGILFLB_01178 6.7e-179 sppA OU signal peptide peptidase SppA
NEGILFLB_01179 8.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEGILFLB_01180 0.0 ytcJ S amidohydrolase
NEGILFLB_01181 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NEGILFLB_01182 2e-29 sspB S spore protein
NEGILFLB_01183 7.8e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NEGILFLB_01184 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
NEGILFLB_01185 5.7e-214 ybdO S Domain of unknown function (DUF4885)
NEGILFLB_01186 3.2e-150 ybdN
NEGILFLB_01187 5.7e-138 KLT Protein tyrosine kinase
NEGILFLB_01189 4.2e-170 T His Kinase A (phospho-acceptor) domain
NEGILFLB_01190 1.3e-122 T Transcriptional regulatory protein, C terminal
NEGILFLB_01191 2.5e-178 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NEGILFLB_01192 7e-56
NEGILFLB_01193 1.9e-201 ybcL EGP Major facilitator Superfamily
NEGILFLB_01194 5.1e-50 ybzH K Helix-turn-helix domain
NEGILFLB_01196 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NEGILFLB_01197 3.9e-47
NEGILFLB_01198 1.3e-93 can 4.2.1.1 P carbonic anhydrase
NEGILFLB_01199 0.0 ybcC S Belongs to the UPF0753 family
NEGILFLB_01200 2.7e-272 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NEGILFLB_01201 9e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NEGILFLB_01202 3.9e-116 adaA 3.2.2.21 K Transcriptional regulator
NEGILFLB_01203 5.5e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NEGILFLB_01204 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEGILFLB_01205 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEGILFLB_01206 1.5e-224 ybbR S protein conserved in bacteria
NEGILFLB_01207 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEGILFLB_01208 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NEGILFLB_01209 7.2e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_01210 2.2e-202 yceJ EGP Uncharacterised MFS-type transporter YbfB
NEGILFLB_01211 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NEGILFLB_01212 5.1e-229 proV 3.6.3.32 E glycine betaine
NEGILFLB_01213 1.3e-127 opuAB P glycine betaine
NEGILFLB_01214 5.3e-164 opuAC E glycine betaine
NEGILFLB_01215 4.1e-217 amhX S amidohydrolase
NEGILFLB_01216 6.2e-255 ycgA S Membrane
NEGILFLB_01217 7e-81 ycgB
NEGILFLB_01218 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NEGILFLB_01219 1.2e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NEGILFLB_01220 1.8e-290 lctP C L-lactate permease
NEGILFLB_01221 3.9e-263 mdr EGP Major facilitator Superfamily
NEGILFLB_01222 1.3e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_01223 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NEGILFLB_01224 1.3e-150 yqcI S YqcI/YcgG family
NEGILFLB_01225 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NEGILFLB_01226 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NEGILFLB_01227 2.6e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NEGILFLB_01228 2.1e-108 tmrB S AAA domain
NEGILFLB_01230 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NEGILFLB_01231 1.4e-144 yafE Q ubiE/COQ5 methyltransferase family
NEGILFLB_01232 1.8e-176 oxyR3 K LysR substrate binding domain
NEGILFLB_01233 4e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NEGILFLB_01234 2.9e-145 ycgL S Predicted nucleotidyltransferase
NEGILFLB_01235 1.9e-169 ycgM E Proline dehydrogenase
NEGILFLB_01236 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NEGILFLB_01237 5.9e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEGILFLB_01238 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NEGILFLB_01239 2.6e-147 ycgQ S membrane
NEGILFLB_01240 1.2e-139 ycgR S permeases
NEGILFLB_01241 2.5e-155 I alpha/beta hydrolase fold
NEGILFLB_01242 2.5e-186 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NEGILFLB_01243 6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NEGILFLB_01244 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NEGILFLB_01245 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NEGILFLB_01246 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEGILFLB_01247 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NEGILFLB_01248 3.8e-221 nasA P COG2223 Nitrate nitrite transporter
NEGILFLB_01249 1.8e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NEGILFLB_01250 5.1e-107 yciB M ErfK YbiS YcfS YnhG
NEGILFLB_01251 7e-228 yciC S GTPases (G3E family)
NEGILFLB_01252 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NEGILFLB_01253 4e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NEGILFLB_01255 8.7e-23 yckC S membrane
NEGILFLB_01256 6e-26 yckC S membrane
NEGILFLB_01257 3.9e-51 yckD S Protein of unknown function (DUF2680)
NEGILFLB_01258 4.1e-45 K MarR family
NEGILFLB_01259 9.3e-24
NEGILFLB_01260 2.7e-121 S AAA domain
NEGILFLB_01261 1e-294 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEGILFLB_01262 6.5e-69 nin S Competence protein J (ComJ)
NEGILFLB_01263 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
NEGILFLB_01264 1e-179 tlpC 2.7.13.3 NT chemotaxis protein
NEGILFLB_01265 5.6e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NEGILFLB_01266 8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NEGILFLB_01267 1.3e-63 hxlR K transcriptional
NEGILFLB_01268 5.6e-129 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NEGILFLB_01269 2.4e-71 3.4.13.21 S ASCH
NEGILFLB_01270 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEGILFLB_01271 2.6e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NEGILFLB_01272 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NEGILFLB_01273 1.4e-110 yhfK GM NmrA-like family
NEGILFLB_01274 4.7e-301 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NEGILFLB_01275 1.9e-65 yhfM
NEGILFLB_01276 2.2e-232 yhfN 3.4.24.84 O Peptidase M48
NEGILFLB_01277 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NEGILFLB_01278 2.8e-76 VY92_01935 K acetyltransferase
NEGILFLB_01279 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NEGILFLB_01280 4.8e-158 yfmC M Periplasmic binding protein
NEGILFLB_01281 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NEGILFLB_01282 4.5e-197 vraB 2.3.1.9 I Belongs to the thiolase family
NEGILFLB_01283 5.2e-278 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NEGILFLB_01284 5e-91 bioY S BioY family
NEGILFLB_01285 4.9e-182 hemAT NT chemotaxis protein
NEGILFLB_01286 1.2e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NEGILFLB_01287 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_01288 1.3e-32 yhzC S IDEAL
NEGILFLB_01289 9.3e-109 comK K Competence transcription factor
NEGILFLB_01290 1.8e-167 IQ Enoyl-(Acyl carrier protein) reductase
NEGILFLB_01291 9.5e-40 yhjA S Excalibur calcium-binding domain
NEGILFLB_01292 9.8e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEGILFLB_01293 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NEGILFLB_01294 6.7e-60 yhjD
NEGILFLB_01295 9.1e-110 yhjE S SNARE associated Golgi protein
NEGILFLB_01296 1.5e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NEGILFLB_01297 7.3e-283 yhjG CH FAD binding domain
NEGILFLB_01298 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_01301 3.6e-211 glcP G Major Facilitator Superfamily
NEGILFLB_01302 4.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NEGILFLB_01303 3.1e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NEGILFLB_01304 7e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NEGILFLB_01305 3.8e-187 yhjM 5.1.1.1 K Transcriptional regulator
NEGILFLB_01306 1.2e-200 abrB S membrane
NEGILFLB_01307 2.3e-210 EGP Transmembrane secretion effector
NEGILFLB_01308 0.0 S Sugar transport-related sRNA regulator N-term
NEGILFLB_01309 2e-36 yhjQ C COG1145 Ferredoxin
NEGILFLB_01310 1.9e-77 yhjR S Rubrerythrin
NEGILFLB_01311 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NEGILFLB_01312 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NEGILFLB_01313 4.5e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NEGILFLB_01314 0.0 sbcC L COG0419 ATPase involved in DNA repair
NEGILFLB_01315 1.1e-49 yisB V COG1403 Restriction endonuclease
NEGILFLB_01316 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NEGILFLB_01317 4.8e-64 gerPE S Spore germination protein GerPE
NEGILFLB_01318 3.1e-23 gerPD S Spore germination protein
NEGILFLB_01319 5.3e-54 gerPC S Spore germination protein
NEGILFLB_01320 4e-34 gerPB S cell differentiation
NEGILFLB_01321 1.9e-33 gerPA S Spore germination protein
NEGILFLB_01322 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NEGILFLB_01323 2e-174 cotH M Spore Coat
NEGILFLB_01324 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NEGILFLB_01325 3e-57 yisL S UPF0344 protein
NEGILFLB_01326 0.0 wprA O Belongs to the peptidase S8 family
NEGILFLB_01327 1.5e-100 yisN S Protein of unknown function (DUF2777)
NEGILFLB_01328 0.0 asnO 6.3.5.4 E Asparagine synthase
NEGILFLB_01329 4.7e-88 yizA S Damage-inducible protein DinB
NEGILFLB_01330 1.1e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NEGILFLB_01331 1.5e-242 yisQ V Mate efflux family protein
NEGILFLB_01332 2.7e-160 yisR K Transcriptional regulator
NEGILFLB_01333 6.9e-184 purR K helix_turn _helix lactose operon repressor
NEGILFLB_01334 9.1e-192 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NEGILFLB_01335 1.8e-92 yisT S DinB family
NEGILFLB_01336 6e-106 argO S Lysine exporter protein LysE YggA
NEGILFLB_01337 3.1e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEGILFLB_01338 4.4e-35 mcbG S Pentapeptide repeats (9 copies)
NEGILFLB_01339 2.7e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NEGILFLB_01340 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NEGILFLB_01341 1.9e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NEGILFLB_01342 1.2e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NEGILFLB_01343 1.5e-118 comB 3.1.3.71 H Belongs to the ComB family
NEGILFLB_01344 1.6e-140 yitD 4.4.1.19 S synthase
NEGILFLB_01345 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEGILFLB_01346 4.1e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NEGILFLB_01347 4.4e-228 yitG EGP Major facilitator Superfamily
NEGILFLB_01348 1.8e-153 yitH K Acetyltransferase (GNAT) domain
NEGILFLB_01349 1e-70 yjcF S Acetyltransferase (GNAT) domain
NEGILFLB_01350 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NEGILFLB_01351 5.6e-54 yajQ S Belongs to the UPF0234 family
NEGILFLB_01352 3.4e-160 cvfB S protein conserved in bacteria
NEGILFLB_01353 8.5e-94
NEGILFLB_01354 2.8e-171
NEGILFLB_01355 1.5e-97 S Sporulation delaying protein SdpA
NEGILFLB_01356 4.5e-58 K Transcriptional regulator PadR-like family
NEGILFLB_01357 4.7e-92
NEGILFLB_01358 1.4e-44 yitR S Domain of unknown function (DUF3784)
NEGILFLB_01359 2.2e-309 nprB 3.4.24.28 E Peptidase M4
NEGILFLB_01360 5.5e-158 yitS S protein conserved in bacteria
NEGILFLB_01361 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NEGILFLB_01362 3.8e-73 ipi S Intracellular proteinase inhibitor
NEGILFLB_01363 1.2e-17 S Protein of unknown function (DUF3813)
NEGILFLB_01364 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NEGILFLB_01365 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NEGILFLB_01366 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NEGILFLB_01367 1.5e-22 pilT S Proteolipid membrane potential modulator
NEGILFLB_01368 1.9e-267 yitY C D-arabinono-1,4-lactone oxidase
NEGILFLB_01369 1.7e-88 norB G Major Facilitator Superfamily
NEGILFLB_01370 7.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEGILFLB_01371 5.9e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEGILFLB_01372 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NEGILFLB_01373 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NEGILFLB_01374 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NEGILFLB_01375 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NEGILFLB_01376 4.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEGILFLB_01377 9.5e-28 yjzC S YjzC-like protein
NEGILFLB_01378 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NEGILFLB_01379 6.2e-142 yjaU I carboxylic ester hydrolase activity
NEGILFLB_01380 8.4e-99 yjaV
NEGILFLB_01381 2.5e-183 med S Transcriptional activator protein med
NEGILFLB_01382 7.3e-26 comZ S ComZ
NEGILFLB_01383 3.9e-10 yjzB
NEGILFLB_01384 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEGILFLB_01385 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEGILFLB_01386 6.6e-150 yjaZ O Zn-dependent protease
NEGILFLB_01387 3.4e-39 S COG NOG14552 non supervised orthologous group
NEGILFLB_01389 4.4e-29 K Transcriptional regulator
NEGILFLB_01390 3.8e-76 ygaO
NEGILFLB_01391 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEGILFLB_01393 8.4e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NEGILFLB_01394 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NEGILFLB_01395 2.1e-169 ssuA M Sulfonate ABC transporter
NEGILFLB_01396 8.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NEGILFLB_01397 2.1e-263 ydcQ D Ftsk spoiiie family protein
NEGILFLB_01398 2.5e-200 nicK L Replication initiation factor
NEGILFLB_01399 5.5e-36
NEGILFLB_01400 2.2e-88 cotE S Spore coat protein
NEGILFLB_01401 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEGILFLB_01402 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEGILFLB_01403 8.9e-70 S Regulatory protein YrvL
NEGILFLB_01405 6e-97 ymcC S Membrane
NEGILFLB_01406 9.3e-107 pksA K Transcriptional regulator
NEGILFLB_01407 6.3e-125 pksB 3.1.2.6 S Polyketide biosynthesis
NEGILFLB_01408 6.4e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NEGILFLB_01410 6.9e-181 pksD Q Acyl transferase domain
NEGILFLB_01411 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NEGILFLB_01412 1.4e-37 acpK IQ Phosphopantetheine attachment site
NEGILFLB_01413 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEGILFLB_01414 1.5e-244 pksG 2.3.3.10 I synthase
NEGILFLB_01415 4.2e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
NEGILFLB_01416 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NEGILFLB_01419 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_01420 0.0 vicK 2.7.13.3 T Histidine kinase
NEGILFLB_01421 3.6e-260 yycH S protein conserved in bacteria
NEGILFLB_01422 7.3e-155 yycI S protein conserved in bacteria
NEGILFLB_01423 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NEGILFLB_01424 3.5e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NEGILFLB_01425 2.9e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NEGILFLB_01426 3.6e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NEGILFLB_01427 4.8e-260 rocE E amino acid
NEGILFLB_01428 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NEGILFLB_01430 1.5e-187 S aspartate phosphatase
NEGILFLB_01431 2.2e-84 yycN 2.3.1.128 K Acetyltransferase
NEGILFLB_01432 2.2e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NEGILFLB_01433 8.7e-207 yycP
NEGILFLB_01434 1.7e-30 yycQ S Protein of unknown function (DUF2651)
NEGILFLB_01436 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NEGILFLB_01437 4.1e-66
NEGILFLB_01438 1.1e-09 S YyzF-like protein
NEGILFLB_01439 3.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEGILFLB_01440 3.7e-36 L ScaI restriction endonuclease
NEGILFLB_01441 2.5e-48 L ScaI restriction endonuclease
NEGILFLB_01442 3.2e-104 L DNA methylAse
NEGILFLB_01443 1.9e-47 radC L RadC-like JAB domain
NEGILFLB_01444 2.6e-15 L AAA ATPase domain
NEGILFLB_01446 4.7e-43 S MazG-like family
NEGILFLB_01447 7.9e-246 L Uncharacterized conserved protein (DUF2075)
NEGILFLB_01448 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NEGILFLB_01449 2.3e-11
NEGILFLB_01450 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NEGILFLB_01451 1.4e-92 M1-753 M FR47-like protein
NEGILFLB_01452 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NEGILFLB_01453 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NEGILFLB_01454 3.9e-84 yuaE S DinB superfamily
NEGILFLB_01455 1.1e-106 yuaD
NEGILFLB_01456 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
NEGILFLB_01457 3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NEGILFLB_01458 3.6e-94 yuaC K Belongs to the GbsR family
NEGILFLB_01459 2.2e-91 yuaB
NEGILFLB_01460 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NEGILFLB_01461 1.1e-234 ktrB P Potassium
NEGILFLB_01462 1e-38 yiaA S yiaA/B two helix domain
NEGILFLB_01463 2.1e-151 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEGILFLB_01464 5.4e-273 yubD P Major Facilitator Superfamily
NEGILFLB_01465 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NEGILFLB_01467 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEGILFLB_01468 9.1e-196 yubA S transporter activity
NEGILFLB_01469 9.7e-183 ygjR S Oxidoreductase
NEGILFLB_01470 2e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NEGILFLB_01471 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NEGILFLB_01472 2.2e-279 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NEGILFLB_01473 1.3e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NEGILFLB_01474 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NEGILFLB_01475 5.1e-239 mcpA NT chemotaxis protein
NEGILFLB_01476 8.5e-295 mcpA NT chemotaxis protein
NEGILFLB_01477 1.5e-222 mcpA NT chemotaxis protein
NEGILFLB_01478 3.2e-225 mcpA NT chemotaxis protein
NEGILFLB_01479 1.7e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NEGILFLB_01480 1e-35
NEGILFLB_01481 2.1e-72 yugU S Uncharacterised protein family UPF0047
NEGILFLB_01482 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NEGILFLB_01483 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NEGILFLB_01484 1.4e-116 yugP S Zn-dependent protease
NEGILFLB_01485 2.3e-38
NEGILFLB_01486 9.3e-53 mstX S Membrane-integrating protein Mistic
NEGILFLB_01487 2.2e-182 yugO P COG1226 Kef-type K transport systems
NEGILFLB_01488 1.3e-72 yugN S YugN-like family
NEGILFLB_01490 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NEGILFLB_01491 1.1e-228 yugK C Dehydrogenase
NEGILFLB_01492 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NEGILFLB_01493 1.1e-34 yuzA S Domain of unknown function (DUF378)
NEGILFLB_01494 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NEGILFLB_01495 2.1e-199 yugH 2.6.1.1 E Aminotransferase
NEGILFLB_01496 1.6e-85 alaR K Transcriptional regulator
NEGILFLB_01497 7.9e-154 yugF I Hydrolase
NEGILFLB_01498 1.1e-40 yugE S Domain of unknown function (DUF1871)
NEGILFLB_01499 2.6e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NEGILFLB_01500 1.3e-232 T PhoQ Sensor
NEGILFLB_01501 7.4e-70 kapB G Kinase associated protein B
NEGILFLB_01502 4.2e-115 kapD L the KinA pathway to sporulation
NEGILFLB_01504 4.2e-184 yuxJ EGP Major facilitator Superfamily
NEGILFLB_01505 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NEGILFLB_01506 1.7e-72 yuxK S protein conserved in bacteria
NEGILFLB_01507 6.3e-78 yufK S Family of unknown function (DUF5366)
NEGILFLB_01508 1.1e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NEGILFLB_01509 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NEGILFLB_01510 2.1e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NEGILFLB_01511 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NEGILFLB_01512 1.6e-183 yufP S Belongs to the binding-protein-dependent transport system permease family
NEGILFLB_01513 2.5e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
NEGILFLB_01514 8.2e-233 maeN C COG3493 Na citrate symporter
NEGILFLB_01515 5e-15
NEGILFLB_01516 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NEGILFLB_01517 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEGILFLB_01518 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEGILFLB_01519 5.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEGILFLB_01520 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEGILFLB_01521 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEGILFLB_01522 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NEGILFLB_01523 3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NEGILFLB_01524 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEGILFLB_01525 3.8e-143 comP 2.7.13.3 T Histidine kinase
NEGILFLB_01526 1.1e-117 comP 2.7.13.3 T Histidine kinase
NEGILFLB_01528 4.7e-142 comQ H Belongs to the FPP GGPP synthase family
NEGILFLB_01530 3.8e-23 yuzC
NEGILFLB_01531 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NEGILFLB_01532 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEGILFLB_01533 2.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
NEGILFLB_01534 6.7e-66 yueI S Protein of unknown function (DUF1694)
NEGILFLB_01535 7.4e-39 yueH S YueH-like protein
NEGILFLB_01536 1.7e-31 yueG S Spore germination protein gerPA/gerPF
NEGILFLB_01537 3.2e-190 yueF S transporter activity
NEGILFLB_01538 5.2e-71 S Protein of unknown function (DUF2283)
NEGILFLB_01539 2.9e-24 S Protein of unknown function (DUF2642)
NEGILFLB_01540 1.4e-95 yueE S phosphohydrolase
NEGILFLB_01541 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_01542 3.3e-64 yueC S Family of unknown function (DUF5383)
NEGILFLB_01543 0.0 esaA S type VII secretion protein EsaA
NEGILFLB_01544 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NEGILFLB_01545 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NEGILFLB_01546 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NEGILFLB_01547 2.8e-45 esxA S Belongs to the WXG100 family
NEGILFLB_01548 1.8e-226 yukF QT Transcriptional regulator
NEGILFLB_01549 5.7e-203 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NEGILFLB_01550 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NEGILFLB_01551 5e-36 mbtH S MbtH-like protein
NEGILFLB_01552 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_01553 1.7e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NEGILFLB_01554 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NEGILFLB_01555 5e-226 entC 5.4.4.2 HQ Isochorismate synthase
NEGILFLB_01556 8.1e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_01557 3.9e-167 besA S Putative esterase
NEGILFLB_01558 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NEGILFLB_01559 1.1e-93 bioY S Biotin biosynthesis protein
NEGILFLB_01560 3.9e-211 yuiF S antiporter
NEGILFLB_01561 2.9e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NEGILFLB_01562 1.2e-77 yuiD S protein conserved in bacteria
NEGILFLB_01563 1.4e-116 yuiC S protein conserved in bacteria
NEGILFLB_01564 2.4e-26 yuiB S Putative membrane protein
NEGILFLB_01565 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NEGILFLB_01566 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NEGILFLB_01568 2.1e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEGILFLB_01569 5e-116 paiB K Putative FMN-binding domain
NEGILFLB_01570 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEGILFLB_01571 3.7e-63 erpA S Belongs to the HesB IscA family
NEGILFLB_01572 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEGILFLB_01573 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NEGILFLB_01574 3.2e-39 yuzB S Belongs to the UPF0349 family
NEGILFLB_01575 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NEGILFLB_01576 1.1e-55 yuzD S protein conserved in bacteria
NEGILFLB_01577 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NEGILFLB_01578 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NEGILFLB_01579 5.6e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEGILFLB_01580 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NEGILFLB_01581 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
NEGILFLB_01582 6.5e-198 yutH S Spore coat protein
NEGILFLB_01583 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NEGILFLB_01584 1.6e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NEGILFLB_01585 8.6e-75 yutE S Protein of unknown function DUF86
NEGILFLB_01586 9.7e-48 yutD S protein conserved in bacteria
NEGILFLB_01587 4.1e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEGILFLB_01588 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NEGILFLB_01589 2.9e-195 lytH M Peptidase, M23
NEGILFLB_01590 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
NEGILFLB_01591 1.1e-47 yunC S Domain of unknown function (DUF1805)
NEGILFLB_01592 1.7e-262 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NEGILFLB_01593 2e-141 yunE S membrane transporter protein
NEGILFLB_01594 3.6e-170 yunF S Protein of unknown function DUF72
NEGILFLB_01595 1.8e-59 yunG
NEGILFLB_01596 2.5e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NEGILFLB_01597 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
NEGILFLB_01598 3.1e-232 pbuX F Permease family
NEGILFLB_01599 9.6e-223 pbuX F xanthine
NEGILFLB_01600 4.9e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NEGILFLB_01601 1.9e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NEGILFLB_01602 1e-249 yhdG E amino acid
NEGILFLB_01603 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NEGILFLB_01604 3.6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEGILFLB_01605 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEGILFLB_01606 8.1e-45 yhdK S Sigma-M inhibitor protein
NEGILFLB_01607 6.6e-201 yhdL S Sigma factor regulator N-terminal
NEGILFLB_01608 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_01609 1.5e-191 yhdN C Aldo keto reductase
NEGILFLB_01610 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NEGILFLB_01611 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NEGILFLB_01612 4.1e-74 cueR K transcriptional
NEGILFLB_01613 2e-222 yhdR 2.6.1.1 E Aminotransferase
NEGILFLB_01614 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NEGILFLB_01615 3.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEGILFLB_01616 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEGILFLB_01617 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NEGILFLB_01619 1.4e-182 yhdY M Mechanosensitive ion channel
NEGILFLB_01620 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NEGILFLB_01621 1.9e-147 yheN G deacetylase
NEGILFLB_01622 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NEGILFLB_01623 1.6e-228 nhaC C Na H antiporter
NEGILFLB_01624 4.4e-83 nhaX T Belongs to the universal stress protein A family
NEGILFLB_01625 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NEGILFLB_01626 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NEGILFLB_01627 1.5e-109 yheG GM NAD(P)H-binding
NEGILFLB_01628 6.3e-28 sspB S spore protein
NEGILFLB_01629 1.3e-36 yheE S Family of unknown function (DUF5342)
NEGILFLB_01630 2.4e-264 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NEGILFLB_01631 2.4e-214 yheC HJ YheC/D like ATP-grasp
NEGILFLB_01632 2.2e-202 yheB S Belongs to the UPF0754 family
NEGILFLB_01633 9.5e-48 yheA S Belongs to the UPF0342 family
NEGILFLB_01634 2.2e-204 yhaZ L DNA alkylation repair enzyme
NEGILFLB_01635 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NEGILFLB_01636 1.8e-292 hemZ H coproporphyrinogen III oxidase
NEGILFLB_01637 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NEGILFLB_01638 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NEGILFLB_01640 2.1e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
NEGILFLB_01641 2.4e-26 S YhzD-like protein
NEGILFLB_01642 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
NEGILFLB_01643 9.4e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NEGILFLB_01644 8.2e-224 yhaO L DNA repair exonuclease
NEGILFLB_01645 0.0 yhaN L AAA domain
NEGILFLB_01646 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NEGILFLB_01647 1.6e-21 yhaL S Sporulation protein YhaL
NEGILFLB_01648 5.5e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEGILFLB_01649 8.7e-90 yhaK S Putative zincin peptidase
NEGILFLB_01650 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NEGILFLB_01651 1e-113 hpr K Negative regulator of protease production and sporulation
NEGILFLB_01652 8.2e-39 yhaH S YtxH-like protein
NEGILFLB_01653 5.4e-21
NEGILFLB_01654 3.6e-80 trpP S Tryptophan transporter TrpP
NEGILFLB_01655 2.2e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEGILFLB_01656 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NEGILFLB_01657 2.3e-136 ecsA V transporter (ATP-binding protein)
NEGILFLB_01658 1.8e-215 ecsB U ABC transporter
NEGILFLB_01659 1.2e-113 ecsC S EcsC protein family
NEGILFLB_01660 5.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NEGILFLB_01661 1.7e-241 yhfA C membrane
NEGILFLB_01662 4.6e-33 1.15.1.2 C Rubrerythrin
NEGILFLB_01663 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NEGILFLB_01664 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NEGILFLB_01665 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NEGILFLB_01666 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NEGILFLB_01667 7e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NEGILFLB_01668 5.4e-101 yhgD K Transcriptional regulator
NEGILFLB_01669 8.6e-214 yhgE S YhgE Pip N-terminal domain protein
NEGILFLB_01670 1.4e-181 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEGILFLB_01671 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
NEGILFLB_01672 9.1e-101 prsW S Involved in the degradation of specific anti-sigma factors
NEGILFLB_01673 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NEGILFLB_01674 5.5e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NEGILFLB_01675 3.9e-111 ypfA M Flagellar protein YcgR
NEGILFLB_01676 2.4e-23 S Family of unknown function (DUF5359)
NEGILFLB_01677 6.8e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NEGILFLB_01678 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NEGILFLB_01679 1.3e-182 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NEGILFLB_01680 1e-07 S YpzI-like protein
NEGILFLB_01681 1.3e-102 yphA
NEGILFLB_01682 2.1e-160 seaA S YIEGIA protein
NEGILFLB_01683 2.3e-27 ypzH
NEGILFLB_01684 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NEGILFLB_01685 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NEGILFLB_01686 1.6e-18 yphE S Protein of unknown function (DUF2768)
NEGILFLB_01687 1e-136 yphF
NEGILFLB_01688 1.1e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NEGILFLB_01689 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEGILFLB_01690 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NEGILFLB_01691 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NEGILFLB_01692 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NEGILFLB_01693 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NEGILFLB_01694 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NEGILFLB_01695 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NEGILFLB_01696 2.1e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NEGILFLB_01697 4.6e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEGILFLB_01698 7.6e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEGILFLB_01699 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NEGILFLB_01700 1.2e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NEGILFLB_01701 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEGILFLB_01702 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NEGILFLB_01703 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NEGILFLB_01704 2.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NEGILFLB_01705 3.7e-258 mcpC NT chemotaxis protein
NEGILFLB_01706 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEGILFLB_01707 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
NEGILFLB_01708 2.1e-38 splA S Transcriptional regulator
NEGILFLB_01709 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEGILFLB_01710 2.1e-39 ptsH G phosphocarrier protein HPr
NEGILFLB_01711 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NEGILFLB_01712 7.6e-128 glcT K antiterminator
NEGILFLB_01714 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
NEGILFLB_01716 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NEGILFLB_01717 3.8e-09
NEGILFLB_01718 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NEGILFLB_01719 4.9e-90 stoA CO thiol-disulfide
NEGILFLB_01720 2.4e-237 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEGILFLB_01721 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NEGILFLB_01722 2.8e-28
NEGILFLB_01723 6e-25 ykvS S protein conserved in bacteria
NEGILFLB_01724 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NEGILFLB_01725 3.1e-162 G Glycosyl hydrolases family 18
NEGILFLB_01726 3.5e-35 3.5.1.104 M LysM domain
NEGILFLB_01727 5.4e-214 ykvP 3.5.1.28 M Glycosyl transferases group 1
NEGILFLB_01728 3.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
NEGILFLB_01729 7.6e-61 ykvN K HxlR-like helix-turn-helix
NEGILFLB_01730 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NEGILFLB_01731 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NEGILFLB_01732 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NEGILFLB_01733 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NEGILFLB_01734 4e-179 ykvI S membrane
NEGILFLB_01735 0.0 clpE O Belongs to the ClpA ClpB family
NEGILFLB_01736 2.7e-138 motA N flagellar motor
NEGILFLB_01737 2.5e-125 motB N Flagellar motor protein
NEGILFLB_01738 1.3e-75 ykvE K transcriptional
NEGILFLB_01739 1.5e-12
NEGILFLB_01740 4.2e-133 yydH O Peptidase M50
NEGILFLB_01741 7.7e-109 prrC P ABC transporter
NEGILFLB_01742 1.6e-118 S ABC-2 family transporter protein
NEGILFLB_01743 1.9e-124 yydK K Transcriptional regulator
NEGILFLB_01744 4.1e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEGILFLB_01745 3.8e-287 ahpF O Alkyl hydroperoxide reductase
NEGILFLB_01746 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NEGILFLB_01747 2.3e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEGILFLB_01748 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
NEGILFLB_01749 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NEGILFLB_01750 2.8e-126 gntR K transcriptional
NEGILFLB_01751 8.6e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NEGILFLB_01752 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
NEGILFLB_01753 2.6e-118 yxaC M effector of murein hydrolase
NEGILFLB_01754 7.6e-49 S LrgA family
NEGILFLB_01755 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_01756 1.6e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_01757 1.3e-99 yxaF K Transcriptional regulator
NEGILFLB_01758 1.6e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
NEGILFLB_01759 2.6e-222 P Protein of unknown function (DUF418)
NEGILFLB_01760 1.4e-75 yxaI S membrane protein domain
NEGILFLB_01761 2.2e-62 S Family of unknown function (DUF5391)
NEGILFLB_01762 4.4e-92 S PQQ-like domain
NEGILFLB_01763 8.1e-10 yxaI S membrane protein domain
NEGILFLB_01764 3.8e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NEGILFLB_01765 2.4e-209 yxbF K Bacterial regulatory proteins, tetR family
NEGILFLB_01766 1.7e-148 IQ Enoyl-(Acyl carrier protein) reductase
NEGILFLB_01768 0.0 htpG O Molecular chaperone. Has ATPase activity
NEGILFLB_01769 1.1e-243 csbC EGP Major facilitator Superfamily
NEGILFLB_01770 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NEGILFLB_01772 4.1e-175 iolS C Aldo keto reductase
NEGILFLB_01773 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NEGILFLB_01774 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEGILFLB_01775 7.8e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NEGILFLB_01776 1.6e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NEGILFLB_01777 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NEGILFLB_01778 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NEGILFLB_01779 2.5e-234 iolF EGP Major facilitator Superfamily
NEGILFLB_01780 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NEGILFLB_01781 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NEGILFLB_01782 5.6e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NEGILFLB_01783 1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NEGILFLB_01784 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_01785 1e-179 T PhoQ Sensor
NEGILFLB_01786 2.3e-139 yxdL V ABC transporter, ATP-binding protein
NEGILFLB_01787 0.0 yxdM V ABC transporter (permease)
NEGILFLB_01788 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NEGILFLB_01789 6.6e-176 fhuD P ABC transporter
NEGILFLB_01790 1.4e-68
NEGILFLB_01791 5.6e-16 yxeD
NEGILFLB_01792 1.3e-20 yxeE
NEGILFLB_01795 2.6e-149 yidA S hydrolases of the HAD superfamily
NEGILFLB_01796 2.2e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NEGILFLB_01797 5.4e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEGILFLB_01798 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEGILFLB_01799 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NEGILFLB_01800 3.5e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
NEGILFLB_01801 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NEGILFLB_01802 3e-212 yxeP 3.5.1.47 E hydrolase activity
NEGILFLB_01803 5.1e-251 yxeQ S MmgE/PrpD family
NEGILFLB_01804 3.2e-198 eutH E Ethanolamine utilisation protein, EutH
NEGILFLB_01805 4.4e-152 yxxB S Domain of Unknown Function (DUF1206)
NEGILFLB_01806 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NEGILFLB_01807 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NEGILFLB_01808 1.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NEGILFLB_01809 1e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NEGILFLB_01810 2e-250 lysP E amino acid
NEGILFLB_01811 1.1e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NEGILFLB_01812 6.3e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NEGILFLB_01813 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NEGILFLB_01814 1.3e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
NEGILFLB_01815 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NEGILFLB_01816 1.9e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NEGILFLB_01817 5.9e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NEGILFLB_01818 4.4e-278 M nucleic acid phosphodiester bond hydrolysis
NEGILFLB_01819 5.1e-22
NEGILFLB_01821 2.4e-212 yjcL S Protein of unknown function (DUF819)
NEGILFLB_01822 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
NEGILFLB_01823 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NEGILFLB_01824 1.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NEGILFLB_01825 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
NEGILFLB_01826 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NEGILFLB_01827 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEGILFLB_01828 1.7e-38
NEGILFLB_01829 0.0 yjcD 3.6.4.12 L DNA helicase
NEGILFLB_01830 2.9e-38 spoVIF S Stage VI sporulation protein F
NEGILFLB_01833 1.9e-56 yjcA S Protein of unknown function (DUF1360)
NEGILFLB_01834 2.3e-55 cotV S Spore Coat Protein X and V domain
NEGILFLB_01835 3e-32 cotW
NEGILFLB_01836 6.4e-77 cotX S Spore Coat Protein X and V domain
NEGILFLB_01837 3.4e-96 cotY S Spore coat protein Z
NEGILFLB_01838 5.2e-83 cotZ S Spore coat protein
NEGILFLB_01839 2.5e-52 yjbX S Spore coat protein
NEGILFLB_01840 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NEGILFLB_01841 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NEGILFLB_01842 3.9e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NEGILFLB_01843 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NEGILFLB_01844 6.7e-30 thiS H thiamine diphosphate biosynthetic process
NEGILFLB_01845 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
NEGILFLB_01846 1.3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NEGILFLB_01847 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NEGILFLB_01848 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEGILFLB_01849 9.6e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NEGILFLB_01850 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NEGILFLB_01851 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEGILFLB_01852 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NEGILFLB_01853 7.1e-62 yjbL S Belongs to the UPF0738 family
NEGILFLB_01854 2.1e-100 yjbK S protein conserved in bacteria
NEGILFLB_01855 5.5e-82 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NEGILFLB_01856 3.7e-72 yjbI S Bacterial-like globin
NEGILFLB_01857 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NEGILFLB_01859 1.8e-20
NEGILFLB_01860 0.0 pepF E oligoendopeptidase F
NEGILFLB_01861 1.2e-219 yjbF S Competence protein
NEGILFLB_01862 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NEGILFLB_01863 6e-112 yjbE P Integral membrane protein TerC family
NEGILFLB_01864 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEGILFLB_01865 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEGILFLB_01866 2.8e-205 yjbB EGP Major Facilitator Superfamily
NEGILFLB_01867 1.2e-171 oppF E Belongs to the ABC transporter superfamily
NEGILFLB_01868 1.5e-197 oppD P Belongs to the ABC transporter superfamily
NEGILFLB_01869 2.2e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEGILFLB_01870 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEGILFLB_01871 8e-307 oppA E ABC transporter substrate-binding protein
NEGILFLB_01872 1e-276 speA 4.1.1.19 E Arginine
NEGILFLB_01873 1.7e-41 yktA S Belongs to the UPF0223 family
NEGILFLB_01874 4.6e-117 yktB S Belongs to the UPF0637 family
NEGILFLB_01875 7.1e-26 ykzI
NEGILFLB_01876 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
NEGILFLB_01877 3.8e-76 ykzC S Acetyltransferase (GNAT) family
NEGILFLB_01878 5.1e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NEGILFLB_01879 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NEGILFLB_01880 0.0 ylaA
NEGILFLB_01881 2.7e-42 ylaB
NEGILFLB_01882 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_01883 1.2e-11 sigC S Putative zinc-finger
NEGILFLB_01884 2.6e-37 ylaE
NEGILFLB_01885 8.2e-22 S Family of unknown function (DUF5325)
NEGILFLB_01886 0.0 typA T GTP-binding protein TypA
NEGILFLB_01887 4.2e-47 ylaH S YlaH-like protein
NEGILFLB_01888 3.7e-21 S YolD-like protein
NEGILFLB_01891 1.4e-46 yjcS S Antibiotic biosynthesis monooxygenase
NEGILFLB_01893 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NEGILFLB_01894 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NEGILFLB_01895 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NEGILFLB_01896 1e-48 yjdF S Protein of unknown function (DUF2992)
NEGILFLB_01897 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NEGILFLB_01899 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEGILFLB_01900 4.6e-28 S Domain of unknown function (DUF4177)
NEGILFLB_01901 3.9e-51 yjdJ S Domain of unknown function (DUF4306)
NEGILFLB_01902 1.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NEGILFLB_01904 2.7e-263 xynD 3.5.1.104 G Polysaccharide deacetylase
NEGILFLB_01905 1.8e-81 S Protein of unknown function (DUF2690)
NEGILFLB_01906 2.3e-20 yjfB S Putative motility protein
NEGILFLB_01907 9.5e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
NEGILFLB_01908 1.2e-45 T PhoQ Sensor
NEGILFLB_01909 2e-103 yjgB S Domain of unknown function (DUF4309)
NEGILFLB_01910 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NEGILFLB_01911 1.3e-94 yjgD S Protein of unknown function (DUF1641)
NEGILFLB_01913 3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NEGILFLB_01915 8.3e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NEGILFLB_01916 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NEGILFLB_01917 3.1e-29
NEGILFLB_01918 2.1e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NEGILFLB_01919 9.5e-122 ybbM S transport system, permease component
NEGILFLB_01920 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NEGILFLB_01921 2.5e-175 yjlA EG Putative multidrug resistance efflux transporter
NEGILFLB_01922 2e-91 yjlB S Cupin domain
NEGILFLB_01923 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NEGILFLB_01924 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NEGILFLB_01925 5.1e-278 uxaC 5.3.1.12 G glucuronate isomerase
NEGILFLB_01926 1.9e-248 yjmB G symporter YjmB
NEGILFLB_01927 1.2e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NEGILFLB_01928 6.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NEGILFLB_01929 4.6e-210 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NEGILFLB_01930 9.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_01931 5.4e-226 exuT G Sugar (and other) transporter
NEGILFLB_01932 5.2e-184 exuR K transcriptional
NEGILFLB_01933 1.1e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NEGILFLB_01934 2.5e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NEGILFLB_01935 9.7e-130 MA20_18170 S membrane transporter protein
NEGILFLB_01936 2.3e-78 yjoA S DinB family
NEGILFLB_01937 6.1e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NEGILFLB_01938 1e-212 S response regulator aspartate phosphatase
NEGILFLB_01940 6.3e-41 S YCII-related domain
NEGILFLB_01941 7.2e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NEGILFLB_01942 6.8e-60 yjqA S Bacterial PH domain
NEGILFLB_01943 2.8e-108 yjqB S Pfam:DUF867
NEGILFLB_01944 4.4e-160 ydbD P Catalase
NEGILFLB_01945 1.6e-111 xkdA E IrrE N-terminal-like domain
NEGILFLB_01946 2e-55 xre K Helix-turn-helix XRE-family like proteins
NEGILFLB_01948 2.1e-154 xkdB K sequence-specific DNA binding
NEGILFLB_01949 6.4e-119 xkdC L Bacterial dnaA protein
NEGILFLB_01952 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NEGILFLB_01953 4.1e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NEGILFLB_01954 4.5e-138 xtmA L phage terminase small subunit
NEGILFLB_01955 1.4e-253 xtmB S phage terminase, large subunit
NEGILFLB_01956 3.5e-285 yqbA S portal protein
NEGILFLB_01957 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NEGILFLB_01958 5.8e-169 xkdG S Phage capsid family
NEGILFLB_01959 5.1e-63 yqbG S Protein of unknown function (DUF3199)
NEGILFLB_01960 2.5e-64 yqbH S Domain of unknown function (DUF3599)
NEGILFLB_01961 5.4e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
NEGILFLB_01962 3.9e-75 xkdJ
NEGILFLB_01963 2.7e-255 xkdK S Phage tail sheath C-terminal domain
NEGILFLB_01964 6.1e-76 xkdM S Phage tail tube protein
NEGILFLB_01965 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
NEGILFLB_01966 2.6e-10 xkdO L Transglycosylase SLT domain
NEGILFLB_01967 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_01968 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
NEGILFLB_01969 3.6e-106 yrhP E LysE type translocator
NEGILFLB_01970 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NEGILFLB_01971 0.0 levR K PTS system fructose IIA component
NEGILFLB_01972 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
NEGILFLB_01973 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NEGILFLB_01974 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NEGILFLB_01975 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NEGILFLB_01976 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NEGILFLB_01977 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NEGILFLB_01978 1.1e-197 adhA 1.1.1.1 C alcohol dehydrogenase
NEGILFLB_01979 8.2e-25 yphJ 4.1.1.44 S peroxiredoxin activity
NEGILFLB_01980 4.3e-47 yraB K helix_turn_helix, mercury resistance
NEGILFLB_01981 1.1e-49 yraD M Spore coat protein
NEGILFLB_01982 1.7e-25 yraE
NEGILFLB_01983 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NEGILFLB_01984 6.4e-63 yraF M Spore coat protein
NEGILFLB_01985 5.3e-37 yraG
NEGILFLB_01986 1.3e-66 E Glyoxalase-like domain
NEGILFLB_01987 2.4e-61 T sh3 domain protein
NEGILFLB_01988 1.7e-60 T sh3 domain protein
NEGILFLB_01989 2.6e-149 S Alpha beta hydrolase
NEGILFLB_01990 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEGILFLB_01991 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NEGILFLB_01992 6.5e-204 yraM S PrpF protein
NEGILFLB_01993 5.6e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NEGILFLB_01994 3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NEGILFLB_01995 2.5e-56 ybbA S Putative esterase
NEGILFLB_01996 1.4e-118 aacC 2.3.1.81 V aminoglycoside
NEGILFLB_01997 7e-47 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
NEGILFLB_01998 5.9e-50 2.7.7.73, 2.7.7.80 H ThiF family
NEGILFLB_01999 1.6e-45
NEGILFLB_02000 2.6e-63 S Major Facilitator Superfamily
NEGILFLB_02001 2e-56 1.14.11.27 S JmjC domain, hydroxylase
NEGILFLB_02002 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_02003 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_02004 4e-165 feuA P Iron-uptake system-binding protein
NEGILFLB_02005 8e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NEGILFLB_02006 7.8e-238 ybbC 3.2.1.52 S protein conserved in bacteria
NEGILFLB_02007 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NEGILFLB_02008 1.2e-249 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NEGILFLB_02009 4.9e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NEGILFLB_02010 1.9e-150 ybbH K transcriptional
NEGILFLB_02011 8.8e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEGILFLB_02012 1.9e-86 ybbJ J acetyltransferase
NEGILFLB_02013 3.3e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NEGILFLB_02015 2.6e-88 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_02016 3.6e-238 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_02018 3.8e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NEGILFLB_02019 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NEGILFLB_02020 7.1e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NEGILFLB_02021 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NEGILFLB_02022 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEGILFLB_02024 0.0 ydiF S ABC transporter
NEGILFLB_02025 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NEGILFLB_02026 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEGILFLB_02027 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NEGILFLB_02028 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NEGILFLB_02029 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NEGILFLB_02030 2.3e-128 ydiL S CAAX protease self-immunity
NEGILFLB_02031 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEGILFLB_02032 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEGILFLB_02034 1.2e-59 isp O Subtilase family
NEGILFLB_02035 6.4e-19
NEGILFLB_02037 6.3e-57
NEGILFLB_02038 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NEGILFLB_02039 3.8e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NEGILFLB_02040 5.2e-75 yfmK 2.3.1.128 K acetyltransferase
NEGILFLB_02041 2.3e-187 yfmJ S N-terminal domain of oxidoreductase
NEGILFLB_02042 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NEGILFLB_02043 6.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_02044 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_02045 3.6e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NEGILFLB_02046 2.9e-24 S Protein of unknown function (DUF3212)
NEGILFLB_02047 7.6e-58 yflT S Heat induced stress protein YflT
NEGILFLB_02048 8.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NEGILFLB_02049 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
NEGILFLB_02050 5.7e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NEGILFLB_02051 2.9e-117 citT T response regulator
NEGILFLB_02052 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
NEGILFLB_02053 3.2e-226 citM C Citrate transporter
NEGILFLB_02054 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NEGILFLB_02055 1.6e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NEGILFLB_02056 3.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NEGILFLB_02057 6.4e-122 yflK S protein conserved in bacteria
NEGILFLB_02058 8.9e-18 yflJ S Protein of unknown function (DUF2639)
NEGILFLB_02059 4.1e-19 yflI
NEGILFLB_02060 2.4e-50 yflH S Protein of unknown function (DUF3243)
NEGILFLB_02061 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NEGILFLB_02062 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NEGILFLB_02063 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NEGILFLB_02064 6e-67 yhdN S Domain of unknown function (DUF1992)
NEGILFLB_02065 2.2e-252 agcS_1 E Sodium alanine symporter
NEGILFLB_02066 1.7e-193 E Spore germination protein
NEGILFLB_02068 2.5e-206 yfkR S spore germination
NEGILFLB_02069 5.4e-281 yfkQ EG Spore germination protein
NEGILFLB_02070 2.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NEGILFLB_02071 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NEGILFLB_02072 1.8e-133 treR K transcriptional
NEGILFLB_02073 1.1e-124 yfkO C nitroreductase
NEGILFLB_02074 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NEGILFLB_02075 8.7e-90 yfkM 1.11.1.6, 3.5.1.124 S protease
NEGILFLB_02076 8.9e-207 ydiM EGP Major facilitator Superfamily
NEGILFLB_02077 2.1e-29 yfkK S Belongs to the UPF0435 family
NEGILFLB_02078 2e-26 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEGILFLB_02079 1.1e-14 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEGILFLB_02080 2.4e-50 yfkI S gas vesicle protein
NEGILFLB_02081 1.3e-143 yihY S Belongs to the UPF0761 family
NEGILFLB_02082 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NEGILFLB_02083 6.1e-183 cax P COG0387 Ca2 H antiporter
NEGILFLB_02084 1.2e-146 yfkD S YfkD-like protein
NEGILFLB_02085 6e-149 yfkC M Mechanosensitive ion channel
NEGILFLB_02086 5.4e-222 yfkA S YfkB-like domain
NEGILFLB_02087 9.2e-26 yfjT
NEGILFLB_02088 2.6e-154 pdaA G deacetylase
NEGILFLB_02089 3.4e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NEGILFLB_02090 1.7e-184 corA P Mediates influx of magnesium ions
NEGILFLB_02091 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NEGILFLB_02092 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEGILFLB_02093 6.5e-42 S YfzA-like protein
NEGILFLB_02094 6.2e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEGILFLB_02095 6.8e-83 yfjM S Psort location Cytoplasmic, score
NEGILFLB_02096 4.6e-30 yfjL
NEGILFLB_02097 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NEGILFLB_02098 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NEGILFLB_02099 9.6e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEGILFLB_02100 3.6e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NEGILFLB_02101 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NEGILFLB_02102 1.2e-25 sspH S Belongs to the SspH family
NEGILFLB_02103 4e-56 yfjF S UPF0060 membrane protein
NEGILFLB_02104 2.5e-79 S Family of unknown function (DUF5381)
NEGILFLB_02105 1.8e-101 yfjD S Family of unknown function (DUF5381)
NEGILFLB_02106 4.1e-144 yfjC
NEGILFLB_02107 2.3e-189 yfjB
NEGILFLB_02108 1.1e-44 yfjA S Belongs to the WXG100 family
NEGILFLB_02109 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NEGILFLB_02110 1e-139 glvR K Helix-turn-helix domain, rpiR family
NEGILFLB_02111 1.4e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NEGILFLB_02112 0.0 yobO M COG5434 Endopolygalacturonase
NEGILFLB_02113 3.2e-306 yfiB3 V ABC transporter
NEGILFLB_02114 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NEGILFLB_02115 1.3e-64 mhqP S DoxX
NEGILFLB_02116 1.4e-161 yfiE 1.13.11.2 S glyoxalase
NEGILFLB_02117 2e-187 yxjM T Histidine kinase
NEGILFLB_02118 2.8e-109 KT LuxR family transcriptional regulator
NEGILFLB_02119 1.3e-168 V ABC transporter, ATP-binding protein
NEGILFLB_02120 2.3e-207 V ABC-2 family transporter protein
NEGILFLB_02121 9e-204 V COG0842 ABC-type multidrug transport system, permease component
NEGILFLB_02122 8.3e-99 padR K transcriptional
NEGILFLB_02123 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NEGILFLB_02124 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NEGILFLB_02125 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
NEGILFLB_02126 1.9e-281 yfiU EGP Major facilitator Superfamily
NEGILFLB_02127 4.9e-79 yfiV K transcriptional
NEGILFLB_02128 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEGILFLB_02129 2.8e-174 yfiY P ABC transporter substrate-binding protein
NEGILFLB_02130 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_02131 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_02132 1.5e-166 yfhB 5.3.3.17 S PhzF family
NEGILFLB_02133 3.9e-107 yfhC C nitroreductase
NEGILFLB_02134 2.1e-25 yfhD S YfhD-like protein
NEGILFLB_02136 2.3e-170 yfhF S nucleoside-diphosphate sugar epimerase
NEGILFLB_02137 1.6e-140 recX 2.4.1.337 GT4 S Modulates RecA activity
NEGILFLB_02138 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NEGILFLB_02140 3.3e-209 yfhI EGP Major facilitator Superfamily
NEGILFLB_02141 6.2e-20 sspK S reproduction
NEGILFLB_02142 1.3e-44 yfhJ S WVELL protein
NEGILFLB_02143 5.2e-87 batE T Bacterial SH3 domain homologues
NEGILFLB_02144 3.5e-51 yfhL S SdpI/YhfL protein family
NEGILFLB_02145 6.3e-170 yfhM S Alpha beta hydrolase
NEGILFLB_02146 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NEGILFLB_02147 0.0 yfhO S Bacterial membrane protein YfhO
NEGILFLB_02148 4.6e-185 yfhP S membrane-bound metal-dependent
NEGILFLB_02149 3.3e-210 mutY L A G-specific
NEGILFLB_02150 6.9e-36 yfhS
NEGILFLB_02151 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_02152 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NEGILFLB_02153 3.3e-37 ygaB S YgaB-like protein
NEGILFLB_02154 1.3e-104 ygaC J Belongs to the UPF0374 family
NEGILFLB_02155 1.8e-301 ygaD V ABC transporter
NEGILFLB_02156 8.7e-180 ygaE S Membrane
NEGILFLB_02157 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NEGILFLB_02158 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NEGILFLB_02159 4e-80 perR P Belongs to the Fur family
NEGILFLB_02160 2.8e-55 ygzB S UPF0295 protein
NEGILFLB_02161 4.3e-166 ygxA S Nucleotidyltransferase-like
NEGILFLB_02162 4.9e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NEGILFLB_02163 3.1e-159 yyaM EG EamA-like transporter family
NEGILFLB_02164 5.1e-61 yyaN K MerR HTH family regulatory protein
NEGILFLB_02165 1.9e-21 yyaR K acetyltransferase
NEGILFLB_02166 3.8e-107 yyaP 1.5.1.3 H RibD C-terminal domain
NEGILFLB_02167 3.5e-66 yyaQ S YjbR
NEGILFLB_02168 1.3e-93 yyaR K Acetyltransferase (GNAT) domain
NEGILFLB_02169 5e-97 yyaS S Membrane
NEGILFLB_02170 2e-71 yjcF S Acetyltransferase (GNAT) domain
NEGILFLB_02171 5.6e-77 yybA 2.3.1.57 K transcriptional
NEGILFLB_02172 2.3e-100 S Metallo-beta-lactamase superfamily
NEGILFLB_02173 5.9e-67 yybH S SnoaL-like domain
NEGILFLB_02174 2.5e-125
NEGILFLB_02175 4.8e-110 K TipAS antibiotic-recognition domain
NEGILFLB_02176 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NEGILFLB_02178 1.1e-69
NEGILFLB_02179 4.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NEGILFLB_02180 1.4e-68 ydeP3 K Transcriptional regulator
NEGILFLB_02181 3.9e-84 cotF M Spore coat protein
NEGILFLB_02183 2.9e-160 yybS S membrane
NEGILFLB_02184 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NEGILFLB_02185 2.2e-73 rplI J binds to the 23S rRNA
NEGILFLB_02186 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEGILFLB_02187 8.4e-221 yeaN P COG2807 Cyanate permease
NEGILFLB_02188 1.9e-15 yycC K YycC-like protein
NEGILFLB_02190 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NEGILFLB_02191 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NEGILFLB_02192 1.9e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEGILFLB_02193 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEGILFLB_02194 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NEGILFLB_02195 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NEGILFLB_02196 7.4e-186 KLT serine threonine protein kinase
NEGILFLB_02197 1.4e-270 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEGILFLB_02198 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NEGILFLB_02199 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEGILFLB_02200 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NEGILFLB_02201 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NEGILFLB_02202 2.9e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NEGILFLB_02203 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NEGILFLB_02204 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NEGILFLB_02205 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NEGILFLB_02206 6.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NEGILFLB_02207 6.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NEGILFLB_02208 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEGILFLB_02209 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NEGILFLB_02210 4.1e-30 yazB K transcriptional
NEGILFLB_02211 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEGILFLB_02212 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NEGILFLB_02213 6.2e-208 yfmO EGP Major facilitator Superfamily
NEGILFLB_02214 1.4e-69 yfmP K transcriptional
NEGILFLB_02215 6.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
NEGILFLB_02216 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NEGILFLB_02217 1.1e-113 yfmS NT chemotaxis protein
NEGILFLB_02218 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEGILFLB_02219 1.1e-240 yfnA E amino acid
NEGILFLB_02220 5.2e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NEGILFLB_02221 6.6e-205 fsr P COG0477 Permeases of the major facilitator superfamily
NEGILFLB_02222 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
NEGILFLB_02223 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NEGILFLB_02224 1e-178 yfnF M Nucleotide-diphospho-sugar transferase
NEGILFLB_02225 3.2e-172 yfnG 4.2.1.45 M dehydratase
NEGILFLB_02226 7.4e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
NEGILFLB_02227 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NEGILFLB_02228 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NEGILFLB_02229 1.2e-197 yetN S Protein of unknown function (DUF3900)
NEGILFLB_02230 1.8e-209 yetM CH FAD binding domain
NEGILFLB_02231 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_02232 5.3e-105 yetJ S Belongs to the BI1 family
NEGILFLB_02233 5.8e-19 yezD S Uncharacterized small protein (DUF2292)
NEGILFLB_02234 1.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NEGILFLB_02235 2.4e-34
NEGILFLB_02236 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEGILFLB_02237 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NEGILFLB_02238 5.2e-122 yetF S membrane
NEGILFLB_02239 3.5e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NEGILFLB_02240 3.8e-162 lplC G Binding-protein-dependent transport system inner membrane component
NEGILFLB_02241 5.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NEGILFLB_02242 4e-289 lplA G Bacterial extracellular solute-binding protein
NEGILFLB_02243 0.0 yetA
NEGILFLB_02244 1.5e-55 yetA
NEGILFLB_02245 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NEGILFLB_02246 2e-123 yesY E GDSL-like Lipase/Acylhydrolase
NEGILFLB_02247 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NEGILFLB_02248 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NEGILFLB_02249 8.8e-113 yesV S Protein of unknown function, DUF624
NEGILFLB_02250 7.1e-129 yesU S Domain of unknown function (DUF1961)
NEGILFLB_02251 3.7e-128 E GDSL-like Lipase/Acylhydrolase
NEGILFLB_02252 0.0 yesS K Transcriptional regulator
NEGILFLB_02253 2.7e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NEGILFLB_02254 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
NEGILFLB_02255 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NEGILFLB_02256 6.2e-246 yesO G Bacterial extracellular solute-binding protein
NEGILFLB_02257 5.4e-198 yesN K helix_turn_helix, arabinose operon control protein
NEGILFLB_02258 0.0 yesM 2.7.13.3 T Histidine kinase
NEGILFLB_02259 1.8e-102 yesL S Protein of unknown function, DUF624
NEGILFLB_02261 1.5e-100 yesJ K Acetyltransferase (GNAT) family
NEGILFLB_02262 5.2e-104 cotJC P Spore Coat
NEGILFLB_02263 1.5e-45 cotJB S CotJB protein
NEGILFLB_02264 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NEGILFLB_02265 4.2e-150 yesF GM NAD(P)H-binding
NEGILFLB_02266 3.4e-79 yesE S SnoaL-like domain
NEGILFLB_02267 1.8e-99 dhaR3 K Transcriptional regulator
NEGILFLB_02269 2.7e-126 yeeN K transcriptional regulatory protein
NEGILFLB_02271 1.3e-207 S Tetratricopeptide repeat
NEGILFLB_02272 1.2e-178 3.4.24.40 CO amine dehydrogenase activity
NEGILFLB_02273 0.0 L nucleic acid phosphodiester bond hydrolysis
NEGILFLB_02274 3e-81 S Protein of unknown function, DUF600
NEGILFLB_02275 6.1e-35
NEGILFLB_02276 7.8e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEGILFLB_02277 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NEGILFLB_02278 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEGILFLB_02279 1.5e-144 yerO K Transcriptional regulator
NEGILFLB_02280 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEGILFLB_02281 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEGILFLB_02282 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEGILFLB_02283 1.2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEGILFLB_02284 1.6e-123 sapB S MgtC SapB transporter
NEGILFLB_02285 3e-195 yerI S homoserine kinase type II (protein kinase fold)
NEGILFLB_02287 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NEGILFLB_02288 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEGILFLB_02289 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NEGILFLB_02290 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NEGILFLB_02292 5.9e-299 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NEGILFLB_02293 2.4e-50 yerC S protein conserved in bacteria
NEGILFLB_02294 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NEGILFLB_02295 0.0 yerA 3.5.4.2 F adenine deaminase
NEGILFLB_02296 2.7e-27 S Protein of unknown function (DUF2892)
NEGILFLB_02297 4.4e-228 yjeH E Amino acid permease
NEGILFLB_02298 1e-72 K helix_turn_helix ASNC type
NEGILFLB_02299 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
NEGILFLB_02300 6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NEGILFLB_02301 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEGILFLB_02302 2.3e-174 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NEGILFLB_02303 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEGILFLB_02304 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEGILFLB_02305 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEGILFLB_02306 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEGILFLB_02307 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NEGILFLB_02308 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NEGILFLB_02309 1.9e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEGILFLB_02310 2.8e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEGILFLB_02311 8e-28 yebG S NETI protein
NEGILFLB_02312 8.9e-93 yebE S UPF0316 protein
NEGILFLB_02314 6.8e-118 yebC M Membrane
NEGILFLB_02315 1e-211 pbuG S permease
NEGILFLB_02316 5.3e-254 S Domain of unknown function (DUF4179)
NEGILFLB_02317 1.8e-82 K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_02318 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NEGILFLB_02319 0.0 yebA E COG1305 Transglutaminase-like enzymes
NEGILFLB_02320 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NEGILFLB_02321 5e-176 yeaC S COG0714 MoxR-like ATPases
NEGILFLB_02322 1.9e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEGILFLB_02323 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NEGILFLB_02324 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NEGILFLB_02325 4.1e-173 yeaA S Protein of unknown function (DUF4003)
NEGILFLB_02326 4.9e-156 ydjP I Alpha/beta hydrolase family
NEGILFLB_02327 1.4e-34 ydjO S Cold-inducible protein YdjO
NEGILFLB_02329 8e-151 ydjN U Involved in the tonB-independent uptake of proteins
NEGILFLB_02330 4.5e-64 ydjM M Lytic transglycolase
NEGILFLB_02331 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NEGILFLB_02332 7.8e-258 iolT EGP Major facilitator Superfamily
NEGILFLB_02333 1.8e-195 S Ion transport 2 domain protein
NEGILFLB_02334 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
NEGILFLB_02335 1.8e-131 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NEGILFLB_02336 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEGILFLB_02337 8.7e-114 pspA KT Phage shock protein A
NEGILFLB_02338 1.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NEGILFLB_02339 3.1e-251 gutA G MFS/sugar transport protein
NEGILFLB_02340 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
NEGILFLB_02341 0.0 K NB-ARC domain
NEGILFLB_02342 9.4e-26 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NEGILFLB_02343 5.1e-64 yozB S Membrane
NEGILFLB_02346 1.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_02347 3.6e-300 pepF2 E COG1164 Oligoendopeptidase F
NEGILFLB_02348 2.5e-66 S YusW-like protein
NEGILFLB_02349 3.9e-153 yusV 3.6.3.34 HP ABC transporter
NEGILFLB_02350 1.1e-46 yusU S Protein of unknown function (DUF2573)
NEGILFLB_02351 2.2e-157 yusT K LysR substrate binding domain
NEGILFLB_02352 2.6e-108 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_02353 2.7e-64 yusQ S Tautomerase enzyme
NEGILFLB_02354 1.1e-292 yusP P Major facilitator superfamily
NEGILFLB_02355 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NEGILFLB_02356 5.4e-53 yusN M Coat F domain
NEGILFLB_02357 5.1e-40
NEGILFLB_02358 1.2e-163 fadM E Proline dehydrogenase
NEGILFLB_02359 8.1e-09 S YuzL-like protein
NEGILFLB_02360 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NEGILFLB_02361 5.5e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NEGILFLB_02362 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NEGILFLB_02363 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NEGILFLB_02364 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NEGILFLB_02365 1.1e-39 yusG S Protein of unknown function (DUF2553)
NEGILFLB_02366 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NEGILFLB_02367 9.5e-55 traF CO Thioredoxin
NEGILFLB_02368 2.4e-56 yusD S SCP-2 sterol transfer family
NEGILFLB_02369 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEGILFLB_02370 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NEGILFLB_02371 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
NEGILFLB_02372 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NEGILFLB_02373 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NEGILFLB_02374 3.5e-244 sufD O assembly protein SufD
NEGILFLB_02375 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEGILFLB_02376 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NEGILFLB_02377 3.5e-271 sufB O FeS cluster assembly
NEGILFLB_02378 3.2e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEGILFLB_02379 1e-41
NEGILFLB_02381 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NEGILFLB_02382 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NEGILFLB_02383 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NEGILFLB_02384 1e-237 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NEGILFLB_02385 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
NEGILFLB_02386 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
NEGILFLB_02387 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NEGILFLB_02388 3.3e-135 yurK K UTRA
NEGILFLB_02389 5.9e-205 msmX P Belongs to the ABC transporter superfamily
NEGILFLB_02390 1.2e-168 bsn L Ribonuclease
NEGILFLB_02391 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NEGILFLB_02392 2.1e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NEGILFLB_02393 5.2e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NEGILFLB_02394 8.4e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NEGILFLB_02395 2.3e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NEGILFLB_02396 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NEGILFLB_02397 6.9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NEGILFLB_02399 2.7e-52 ydbL
NEGILFLB_02400 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NEGILFLB_02401 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
NEGILFLB_02402 3.7e-180 ydbI S AI-2E family transporter
NEGILFLB_02403 7e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEGILFLB_02404 3.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NEGILFLB_02405 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NEGILFLB_02406 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NEGILFLB_02407 3.2e-155 ydbD P Catalase
NEGILFLB_02408 2.8e-63 ydbC S Domain of unknown function (DUF4937
NEGILFLB_02409 8.9e-59 ydbB G Cupin domain
NEGILFLB_02411 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NEGILFLB_02412 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NEGILFLB_02414 3.9e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NEGILFLB_02415 2.3e-38
NEGILFLB_02416 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NEGILFLB_02417 3.3e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NEGILFLB_02418 0.0 ydaO E amino acid
NEGILFLB_02419 0.0 ydaN S Bacterial cellulose synthase subunit
NEGILFLB_02420 1.3e-232 ydaM M Glycosyl transferase family group 2
NEGILFLB_02421 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NEGILFLB_02422 5.9e-152 ydaK T Diguanylate cyclase, GGDEF domain
NEGILFLB_02423 1.4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NEGILFLB_02424 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEGILFLB_02425 2.5e-74 lrpC K Transcriptional regulator
NEGILFLB_02426 3.6e-45 ydzA EGP Major facilitator Superfamily
NEGILFLB_02427 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NEGILFLB_02428 1.2e-76 ydaG 1.4.3.5 S general stress protein
NEGILFLB_02429 5.6e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NEGILFLB_02430 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NEGILFLB_02431 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_02432 4.5e-98 ydaC Q Methyltransferase domain
NEGILFLB_02433 4.3e-291 ydaB IQ acyl-CoA ligase
NEGILFLB_02434 0.0 mtlR K transcriptional regulator, MtlR
NEGILFLB_02435 9.8e-174 ydhF S Oxidoreductase
NEGILFLB_02436 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NEGILFLB_02437 5.4e-49 yczJ S biosynthesis
NEGILFLB_02439 6.7e-116 ycsK E anatomical structure formation involved in morphogenesis
NEGILFLB_02440 2.7e-132 kipR K Transcriptional regulator
NEGILFLB_02441 4.3e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NEGILFLB_02442 2.7e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NEGILFLB_02443 7.6e-146 ycsI S Belongs to the D-glutamate cyclase family
NEGILFLB_02444 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NEGILFLB_02445 2.3e-139 ycsF S Belongs to the UPF0271 (lamB) family
NEGILFLB_02446 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NEGILFLB_02448 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NEGILFLB_02449 2.8e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NEGILFLB_02450 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NEGILFLB_02451 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NEGILFLB_02452 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NEGILFLB_02453 8.1e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NEGILFLB_02454 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NEGILFLB_02455 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NEGILFLB_02456 1.7e-52
NEGILFLB_02457 4.7e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NEGILFLB_02458 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NEGILFLB_02459 9.3e-99 ycnI S protein conserved in bacteria
NEGILFLB_02460 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_02461 6.1e-149 glcU U Glucose uptake
NEGILFLB_02462 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEGILFLB_02463 1.7e-243 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEGILFLB_02464 1.1e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEGILFLB_02465 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NEGILFLB_02466 1.6e-45 ycnE S Monooxygenase
NEGILFLB_02467 9.8e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NEGILFLB_02468 7.1e-153 ycnC K Transcriptional regulator
NEGILFLB_02469 3.2e-251 ycnB EGP Major facilitator Superfamily
NEGILFLB_02470 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NEGILFLB_02471 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NEGILFLB_02472 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_02473 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEGILFLB_02474 3.8e-238 lysC 2.7.2.4 E Belongs to the aspartokinase family
NEGILFLB_02478 2e-70 S aspartate phosphatase
NEGILFLB_02479 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NEGILFLB_02480 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_02481 3.6e-202 yclI V ABC transporter (permease) YclI
NEGILFLB_02482 2.8e-120 yclH P ABC transporter
NEGILFLB_02483 1.1e-193 gerKB F Spore germination protein
NEGILFLB_02484 2.8e-224 gerKC S spore germination
NEGILFLB_02485 1.8e-279 gerKA EG Spore germination protein
NEGILFLB_02487 1.1e-298 yclG M Pectate lyase superfamily protein
NEGILFLB_02488 8.6e-57 ynfC
NEGILFLB_02489 2.3e-12
NEGILFLB_02490 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEGILFLB_02491 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEGILFLB_02492 6.6e-69 yccU S CoA-binding protein
NEGILFLB_02493 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEGILFLB_02494 1.2e-48 yneR S Belongs to the HesB IscA family
NEGILFLB_02495 2.4e-52 yneQ
NEGILFLB_02496 1.2e-73 yneP S Thioesterase-like superfamily
NEGILFLB_02497 1.1e-34 tlp S Belongs to the Tlp family
NEGILFLB_02498 3.1e-08 sspN S Small acid-soluble spore protein N family
NEGILFLB_02500 5.9e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NEGILFLB_02501 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NEGILFLB_02502 2.5e-14 sspO S Belongs to the SspO family
NEGILFLB_02503 3.9e-19 sspP S Belongs to the SspP family
NEGILFLB_02504 2.2e-63 hspX O Spore coat protein
NEGILFLB_02505 7.6e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NEGILFLB_02506 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NEGILFLB_02507 4.1e-29 ybxH S Family of unknown function (DUF5370)
NEGILFLB_02508 2.6e-149 ybxI 3.5.2.6 V beta-lactamase
NEGILFLB_02509 3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NEGILFLB_02510 4.9e-41 ybyB
NEGILFLB_02511 1.8e-290 ybeC E amino acid
NEGILFLB_02512 3.4e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NEGILFLB_02513 7.3e-258 glpT G -transporter
NEGILFLB_02514 1.5e-34 S Protein of unknown function (DUF2651)
NEGILFLB_02515 4.4e-169 ybfA 3.4.15.5 K FR47-like protein
NEGILFLB_02516 7.9e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
NEGILFLB_02518 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NEGILFLB_02519 3.3e-161 ybfH EG EamA-like transporter family
NEGILFLB_02520 2.3e-145 msmR K AraC-like ligand binding domain
NEGILFLB_02521 5.7e-236 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_02522 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NEGILFLB_02523 7.5e-140 srfAD Q thioesterase
NEGILFLB_02524 5.2e-226 EGP Major Facilitator Superfamily
NEGILFLB_02525 5.1e-88 S YcxB-like protein
NEGILFLB_02526 2.4e-159 ycxC EG EamA-like transporter family
NEGILFLB_02527 1.2e-252 ycxD K GntR family transcriptional regulator
NEGILFLB_02528 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NEGILFLB_02529 9.7e-115 yczE S membrane
NEGILFLB_02530 4.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NEGILFLB_02531 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NEGILFLB_02532 2e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NEGILFLB_02533 5.4e-161 bsdA K LysR substrate binding domain
NEGILFLB_02534 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NEGILFLB_02535 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NEGILFLB_02536 4e-39 bsdD 4.1.1.61 S response to toxic substance
NEGILFLB_02537 3e-81 yclD
NEGILFLB_02538 2.4e-158 yclE 3.4.11.5 S Alpha beta hydrolase
NEGILFLB_02539 5.2e-265 dtpT E amino acid peptide transporter
NEGILFLB_02540 2.1e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NEGILFLB_02541 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NEGILFLB_02542 1.2e-84 gerD
NEGILFLB_02543 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NEGILFLB_02544 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NEGILFLB_02545 2.2e-65 ybaK S Protein of unknown function (DUF2521)
NEGILFLB_02546 4.5e-143 ybaJ Q Methyltransferase domain
NEGILFLB_02547 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NEGILFLB_02548 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEGILFLB_02549 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEGILFLB_02550 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEGILFLB_02551 5.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEGILFLB_02552 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEGILFLB_02553 3.6e-58 rplQ J Ribosomal protein L17
NEGILFLB_02554 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGILFLB_02555 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEGILFLB_02556 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEGILFLB_02557 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NEGILFLB_02558 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEGILFLB_02559 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NEGILFLB_02560 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEGILFLB_02561 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEGILFLB_02562 1.8e-72 rplO J binds to the 23S rRNA
NEGILFLB_02563 1.9e-23 rpmD J Ribosomal protein L30
NEGILFLB_02564 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEGILFLB_02565 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEGILFLB_02566 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEGILFLB_02567 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEGILFLB_02568 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEGILFLB_02569 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEGILFLB_02570 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEGILFLB_02571 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEGILFLB_02572 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEGILFLB_02573 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NEGILFLB_02574 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEGILFLB_02575 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEGILFLB_02576 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEGILFLB_02577 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEGILFLB_02578 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEGILFLB_02579 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEGILFLB_02580 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
NEGILFLB_02581 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEGILFLB_02582 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NEGILFLB_02583 8.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NEGILFLB_02584 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEGILFLB_02585 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEGILFLB_02586 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEGILFLB_02587 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEGILFLB_02588 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NEGILFLB_02589 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGILFLB_02590 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGILFLB_02591 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NEGILFLB_02592 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEGILFLB_02593 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEGILFLB_02594 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEGILFLB_02595 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEGILFLB_02596 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NEGILFLB_02597 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEGILFLB_02598 4.4e-115 sigH K Belongs to the sigma-70 factor family
NEGILFLB_02599 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NEGILFLB_02600 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEGILFLB_02601 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NEGILFLB_02602 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEGILFLB_02603 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NEGILFLB_02604 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEGILFLB_02605 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NEGILFLB_02606 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NEGILFLB_02607 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NEGILFLB_02608 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NEGILFLB_02609 1.4e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEGILFLB_02610 0.0 clpC O Belongs to the ClpA ClpB family
NEGILFLB_02611 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NEGILFLB_02612 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NEGILFLB_02613 2.9e-76 ctsR K Belongs to the CtsR family
NEGILFLB_02614 1.2e-11
NEGILFLB_02619 9.5e-27
NEGILFLB_02620 9.8e-55
NEGILFLB_02621 5.3e-70
NEGILFLB_02622 4.4e-92 virB11 2.1.1.37 NU Type II/IV secretion system protein
NEGILFLB_02623 2e-19
NEGILFLB_02626 2.1e-228 M domain protein
NEGILFLB_02629 3.9e-07 3.4.21.88 K Transcriptional
NEGILFLB_02631 5.6e-70 S SMART Tetratricopeptide domain protein
NEGILFLB_02632 7.8e-147
NEGILFLB_02636 2e-24 V VanZ like family
NEGILFLB_02637 1.2e-91 cgeD M maturation of the outermost layer of the spore
NEGILFLB_02638 4.1e-144 yiiD K acetyltransferase
NEGILFLB_02640 3.8e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEGILFLB_02641 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NEGILFLB_02642 2.8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NEGILFLB_02643 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NEGILFLB_02644 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NEGILFLB_02645 3.9e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NEGILFLB_02646 2.9e-47 yokU S YokU-like protein, putative antitoxin
NEGILFLB_02647 1.4e-36 yozE S Belongs to the UPF0346 family
NEGILFLB_02648 6e-123 yodN
NEGILFLB_02650 2.8e-24 yozD S YozD-like protein
NEGILFLB_02651 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
NEGILFLB_02652 3.6e-54 yodL S YodL-like
NEGILFLB_02653 5.3e-09
NEGILFLB_02654 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NEGILFLB_02655 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NEGILFLB_02656 1.5e-23 yodI
NEGILFLB_02657 7.8e-126 yodH Q Methyltransferase
NEGILFLB_02658 5.9e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NEGILFLB_02659 1.5e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEGILFLB_02660 6.2e-28 S Protein of unknown function (DUF3311)
NEGILFLB_02661 1.3e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
NEGILFLB_02662 3.8e-113 mhqD S Carboxylesterase
NEGILFLB_02663 1.4e-107 yodC C nitroreductase
NEGILFLB_02664 4.4e-55 yodB K transcriptional
NEGILFLB_02665 4.7e-64 yodA S tautomerase
NEGILFLB_02666 3e-203 gntP EG COG2610 H gluconate symporter and related permeases
NEGILFLB_02667 2.6e-09
NEGILFLB_02668 4.3e-64 yozR S COG0071 Molecular chaperone (small heat shock protein)
NEGILFLB_02669 5.6e-161 rarD S -transporter
NEGILFLB_02670 4.3e-43
NEGILFLB_02671 2.8e-60 yojF S Protein of unknown function (DUF1806)
NEGILFLB_02672 3.7e-125 yojG S deacetylase
NEGILFLB_02673 7.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NEGILFLB_02674 1.6e-244 norM V Multidrug efflux pump
NEGILFLB_02676 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEGILFLB_02677 2.6e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NEGILFLB_02678 2.1e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NEGILFLB_02679 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NEGILFLB_02680 1.9e-161 yojN S ATPase family associated with various cellular activities (AAA)
NEGILFLB_02681 0.0 yojO P Von Willebrand factor
NEGILFLB_02682 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NEGILFLB_02683 5.3e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NEGILFLB_02684 5.6e-167 yocS S -transporter
NEGILFLB_02685 5.8e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NEGILFLB_02686 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
NEGILFLB_02687 7.1e-300 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NEGILFLB_02688 6.1e-79 carD K Transcription factor
NEGILFLB_02689 3.1e-30 ydzE EG spore germination
NEGILFLB_02690 1.6e-160 rhaS5 K AraC-like ligand binding domain
NEGILFLB_02691 3.4e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NEGILFLB_02692 2.3e-164 ydeE K AraC family transcriptional regulator
NEGILFLB_02693 2.6e-258 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEGILFLB_02694 9.9e-220 ydeG EGP Major facilitator superfamily
NEGILFLB_02695 2.7e-45 ydeH
NEGILFLB_02696 3.9e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NEGILFLB_02697 7.3e-102
NEGILFLB_02698 5.9e-152 ydeK EG -transporter
NEGILFLB_02699 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEGILFLB_02700 2.7e-73 maoC I N-terminal half of MaoC dehydratase
NEGILFLB_02701 2.5e-104 ydeN S Serine hydrolase
NEGILFLB_02702 1.2e-55 K HxlR-like helix-turn-helix
NEGILFLB_02703 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NEGILFLB_02704 2.4e-56 arsR K transcriptional
NEGILFLB_02705 5.7e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NEGILFLB_02706 6e-143 ydfB J GNAT acetyltransferase
NEGILFLB_02707 2.4e-148 lytR K Transcriptional regulator
NEGILFLB_02708 7e-123 nodB1 G deacetylase
NEGILFLB_02709 9.5e-158
NEGILFLB_02710 6.6e-212 T GHKL domain
NEGILFLB_02711 1.3e-121 T Transcriptional regulatory protein, C terminal
NEGILFLB_02712 4.4e-150 ydfC EG EamA-like transporter family
NEGILFLB_02713 4.6e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEGILFLB_02714 5.5e-115 ydfE S Flavin reductase like domain
NEGILFLB_02715 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NEGILFLB_02716 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NEGILFLB_02718 1.2e-176 ydfH 2.7.13.3 T Histidine kinase
NEGILFLB_02719 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEGILFLB_02720 0.0 ydfJ S drug exporters of the RND superfamily
NEGILFLB_02721 8.5e-117 S Protein of unknown function (DUF554)
NEGILFLB_02722 1.2e-143 K Bacterial transcription activator, effector binding domain
NEGILFLB_02723 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEGILFLB_02724 3.8e-108 ydfN C nitroreductase
NEGILFLB_02725 6.8e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NEGILFLB_02726 1.2e-62 mhqP S DoxX
NEGILFLB_02727 1e-54 traF CO Thioredoxin
NEGILFLB_02728 5.5e-15 ydgA S Spore germination protein gerPA/gerPF
NEGILFLB_02729 8.2e-29
NEGILFLB_02731 1.9e-45 ydfR S Protein of unknown function (DUF421)
NEGILFLB_02732 2.3e-30 ydfR S Protein of unknown function (DUF421)
NEGILFLB_02733 1.5e-121 ydfS S Protein of unknown function (DUF421)
NEGILFLB_02734 1.1e-66 cotP O Belongs to the small heat shock protein (HSP20) family
NEGILFLB_02735 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
NEGILFLB_02736 2.7e-34 ydgB S Spore germination protein gerPA/gerPF
NEGILFLB_02737 4.5e-98 K Bacterial regulatory proteins, tetR family
NEGILFLB_02738 2.4e-51 S DoxX-like family
NEGILFLB_02739 2.7e-82 yycN 2.3.1.128 K Acetyltransferase
NEGILFLB_02740 3.7e-304 expZ S ABC transporter
NEGILFLB_02741 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NEGILFLB_02742 4.3e-89 dinB S DinB family
NEGILFLB_02743 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_02744 0.0 ydgH S drug exporters of the RND superfamily
NEGILFLB_02745 1.5e-74 MA20_09250 K Bacterial regulatory proteins, tetR family
NEGILFLB_02746 1e-120 IQ KR domain
NEGILFLB_02747 8.8e-113 drgA C nitroreductase
NEGILFLB_02748 1.3e-67 ydgJ K Winged helix DNA-binding domain
NEGILFLB_02749 6.9e-93 ydcN K Cupin domain
NEGILFLB_02750 7.8e-97 azlC E branched-chain amino acid
NEGILFLB_02751 2.5e-42 azlD S Branched-chain amino acid transport protein (AzlD)
NEGILFLB_02753 1.7e-205 tcaB EGP Major facilitator Superfamily
NEGILFLB_02754 7.4e-119 ydhB S membrane transporter protein
NEGILFLB_02755 6.3e-117 ydhC K FCD
NEGILFLB_02756 1.5e-241 ydhD M Glycosyl hydrolase
NEGILFLB_02757 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NEGILFLB_02758 5.1e-125
NEGILFLB_02759 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NEGILFLB_02760 1.6e-66 frataxin S Domain of unknown function (DU1801)
NEGILFLB_02762 9.5e-83 K Acetyltransferase (GNAT) domain
NEGILFLB_02763 2.4e-181 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NEGILFLB_02764 2.3e-96 ydhK M Protein of unknown function (DUF1541)
NEGILFLB_02765 4.6e-200 pbuE EGP Major facilitator Superfamily
NEGILFLB_02766 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NEGILFLB_02767 9.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NEGILFLB_02768 1.4e-232 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEGILFLB_02769 3.1e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEGILFLB_02770 3.7e-131 ydhQ K UTRA
NEGILFLB_02771 3.3e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NEGILFLB_02772 1.1e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
NEGILFLB_02773 8.4e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NEGILFLB_02774 2.3e-156 ydhU P Catalase
NEGILFLB_02776 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NEGILFLB_02778 7.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEGILFLB_02779 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NEGILFLB_02780 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEGILFLB_02781 1e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NEGILFLB_02782 0.0 carB 6.3.5.5 F Belongs to the CarB family
NEGILFLB_02783 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NEGILFLB_02784 3.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEGILFLB_02785 5.9e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NEGILFLB_02786 3.8e-230 pyrP F Xanthine uracil
NEGILFLB_02787 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEGILFLB_02788 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NEGILFLB_02789 3.1e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEGILFLB_02790 8.5e-63 dksA T COG1734 DnaK suppressor protein
NEGILFLB_02791 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEGILFLB_02792 2.6e-67 divIVA D Cell division initiation protein
NEGILFLB_02793 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NEGILFLB_02794 1.3e-39 yggT S membrane
NEGILFLB_02795 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEGILFLB_02796 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NEGILFLB_02797 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NEGILFLB_02798 2.4e-37 ylmC S sporulation protein
NEGILFLB_02799 2.6e-249 argE 3.5.1.16 E Acetylornithine deacetylase
NEGILFLB_02800 5.3e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NEGILFLB_02801 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEGILFLB_02802 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEGILFLB_02803 1.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NEGILFLB_02804 0.0 bpr O COG1404 Subtilisin-like serine proteases
NEGILFLB_02805 4.4e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEGILFLB_02806 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEGILFLB_02807 6.2e-58 sbp S small basic protein
NEGILFLB_02808 3e-102 ylxX S protein conserved in bacteria
NEGILFLB_02809 2.4e-103 ylxW S protein conserved in bacteria
NEGILFLB_02810 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NEGILFLB_02811 9e-167 murB 1.3.1.98 M cell wall formation
NEGILFLB_02812 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEGILFLB_02813 5.7e-186 spoVE D Belongs to the SEDS family
NEGILFLB_02814 3.2e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEGILFLB_02815 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEGILFLB_02816 8.9e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEGILFLB_02817 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NEGILFLB_02818 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NEGILFLB_02819 3.7e-44 ftsL D Essential cell division protein
NEGILFLB_02820 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEGILFLB_02821 2.9e-78 mraZ K Belongs to the MraZ family
NEGILFLB_02822 6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NEGILFLB_02823 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEGILFLB_02824 1.5e-88 ylbP K n-acetyltransferase
NEGILFLB_02825 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NEGILFLB_02826 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NEGILFLB_02827 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NEGILFLB_02829 3.3e-228 ylbM S Belongs to the UPF0348 family
NEGILFLB_02830 6.8e-187 ylbL T Belongs to the peptidase S16 family
NEGILFLB_02831 3.7e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
NEGILFLB_02832 1.2e-219 ylbJ S Sporulation integral membrane protein YlbJ
NEGILFLB_02833 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEGILFLB_02834 1.1e-95 rsmD 2.1.1.171 L Methyltransferase
NEGILFLB_02835 7.5e-39 ylbG S UPF0298 protein
NEGILFLB_02836 1.8e-75 ylbF S Belongs to the UPF0342 family
NEGILFLB_02837 6.7e-37 ylbE S YlbE-like protein
NEGILFLB_02838 4.1e-63 ylbD S Putative coat protein
NEGILFLB_02839 2.8e-199 ylbC S protein with SCP PR1 domains
NEGILFLB_02840 7.5e-74 ylbB T COG0517 FOG CBS domain
NEGILFLB_02841 2e-61 ylbA S YugN-like family
NEGILFLB_02842 1.5e-166 ctaG S cytochrome c oxidase
NEGILFLB_02843 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NEGILFLB_02844 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NEGILFLB_02845 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NEGILFLB_02846 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NEGILFLB_02847 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NEGILFLB_02848 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NEGILFLB_02849 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NEGILFLB_02850 2.5e-212 ftsW D Belongs to the SEDS family
NEGILFLB_02851 8.7e-44 ylaN S Belongs to the UPF0358 family
NEGILFLB_02852 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NEGILFLB_02853 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NEGILFLB_02854 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NEGILFLB_02855 1.2e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEGILFLB_02859 3.3e-43 yddA
NEGILFLB_02861 1.1e-166 yddB S Conjugative transposon protein TcpC
NEGILFLB_02862 6.7e-40 yddC
NEGILFLB_02863 2e-94 yddD S TcpE family
NEGILFLB_02864 0.0 yddE S AAA-like domain
NEGILFLB_02865 1.3e-54 S Domain of unknown function (DUF1874)
NEGILFLB_02866 0.0 yddG S maturation of SSU-rRNA
NEGILFLB_02867 2.2e-187 yddH CBM50 M Lysozyme-like
NEGILFLB_02868 3.8e-82 yddI
NEGILFLB_02869 3.9e-55 S Domain of unknown function with cystatin-like fold (DUF4467)
NEGILFLB_02870 2.6e-33 C Domain of unknown function (DUF4145)
NEGILFLB_02871 8.8e-74 S response regulator aspartate phosphatase
NEGILFLB_02873 1.8e-79 S FRG
NEGILFLB_02874 1.4e-64 badR K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_02875 1.5e-224 yusP P Major facilitator superfamily
NEGILFLB_02876 1.1e-117 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_02877 1.3e-93
NEGILFLB_02878 5.6e-34 K Helix-turn-helix XRE-family like proteins
NEGILFLB_02879 1.1e-40
NEGILFLB_02880 9.1e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NEGILFLB_02881 8.7e-30 cspL K Cold shock
NEGILFLB_02882 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEGILFLB_02883 1.2e-53 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEGILFLB_02884 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEGILFLB_02885 2.5e-107 jag S single-stranded nucleic acid binding R3H
NEGILFLB_02886 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEGILFLB_02887 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEGILFLB_02888 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NEGILFLB_02889 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NEGILFLB_02890 3.6e-67 S Bacterial PH domain
NEGILFLB_02891 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NEGILFLB_02892 2.1e-149 spo0J K Belongs to the ParB family
NEGILFLB_02893 1.6e-111 yyaC S Sporulation protein YyaC
NEGILFLB_02894 8.1e-177 yyaD S Membrane
NEGILFLB_02895 2.3e-33 yyzM S protein conserved in bacteria
NEGILFLB_02896 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEGILFLB_02897 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEGILFLB_02898 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NEGILFLB_02899 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEGILFLB_02900 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEGILFLB_02901 8.9e-144 xth 3.1.11.2 L exodeoxyribonuclease III
NEGILFLB_02902 8.1e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NEGILFLB_02903 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEGILFLB_02904 2.4e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NEGILFLB_02905 6.1e-244 EGP Major facilitator superfamily
NEGILFLB_02906 1.1e-167 yyaK S CAAX protease self-immunity
NEGILFLB_02907 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NEGILFLB_02908 8.9e-83 ydcK S Belongs to the SprT family
NEGILFLB_02909 0.0 yhgF K COG2183 Transcriptional accessory protein
NEGILFLB_02910 6.1e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
NEGILFLB_02911 7.4e-82 ydcG S EVE domain
NEGILFLB_02914 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NEGILFLB_02915 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEGILFLB_02916 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NEGILFLB_02917 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
NEGILFLB_02918 3.5e-188 rsbU 3.1.3.3 KT phosphatase
NEGILFLB_02919 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NEGILFLB_02920 5.2e-57 rsbS T antagonist
NEGILFLB_02921 1.3e-143 rsbR T Positive regulator of sigma-B
NEGILFLB_02922 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NEGILFLB_02923 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NEGILFLB_02924 8.2e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEGILFLB_02925 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NEGILFLB_02926 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEGILFLB_02927 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NEGILFLB_02928 8.6e-260 ydbT S Membrane
NEGILFLB_02929 2.1e-82 ydbS S Bacterial PH domain
NEGILFLB_02930 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NEGILFLB_02931 4.3e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEGILFLB_02932 7.4e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NEGILFLB_02933 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NEGILFLB_02934 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEGILFLB_02935 2.2e-07 S Fur-regulated basic protein A
NEGILFLB_02936 1.1e-18 S Fur-regulated basic protein B
NEGILFLB_02937 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_02938 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_02946 8.7e-113 yhzB S B3/4 domain
NEGILFLB_02947 3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NEGILFLB_02948 4.8e-176 yhbB S Putative amidase domain
NEGILFLB_02949 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEGILFLB_02950 3e-108 yhbD K Protein of unknown function (DUF4004)
NEGILFLB_02951 1.3e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NEGILFLB_02952 1.3e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NEGILFLB_02953 0.0 prkA T Ser protein kinase
NEGILFLB_02954 2.5e-225 yhbH S Belongs to the UPF0229 family
NEGILFLB_02955 2.2e-76 yhbI K DNA-binding transcription factor activity
NEGILFLB_02956 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NEGILFLB_02957 2.9e-269 yhcA EGP Major facilitator Superfamily
NEGILFLB_02958 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NEGILFLB_02959 2.8e-37 yhcC
NEGILFLB_02960 7.8e-55
NEGILFLB_02961 6.6e-60 yhcF K Transcriptional regulator
NEGILFLB_02962 5.2e-122 yhcG V ABC transporter, ATP-binding protein
NEGILFLB_02963 1.9e-164 yhcH V ABC transporter, ATP-binding protein
NEGILFLB_02964 1.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NEGILFLB_02965 1e-30 cspB K Cold-shock protein
NEGILFLB_02966 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
NEGILFLB_02967 4.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NEGILFLB_02968 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEGILFLB_02969 7.1e-77 S Protein of unknown function (DUF2812)
NEGILFLB_02970 1.2e-49 K Transcriptional regulator PadR-like family
NEGILFLB_02971 1.2e-39 yhcM
NEGILFLB_02972 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEGILFLB_02973 4e-165 yhcP
NEGILFLB_02974 5.2e-100 yhcQ M Spore coat protein
NEGILFLB_02975 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NEGILFLB_02976 5.1e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NEGILFLB_02977 2.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NEGILFLB_02978 2.1e-67 yhcU S Family of unknown function (DUF5365)
NEGILFLB_02979 9.9e-68 yhcV S COG0517 FOG CBS domain
NEGILFLB_02980 3e-119 yhcW 5.4.2.6 S hydrolase
NEGILFLB_02981 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NEGILFLB_02982 2.1e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEGILFLB_02983 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NEGILFLB_02984 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NEGILFLB_02985 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEGILFLB_02986 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NEGILFLB_02987 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NEGILFLB_02988 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
NEGILFLB_02989 2.7e-109 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEGILFLB_02990 2.7e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
NEGILFLB_02991 1.2e-38 yhdB S YhdB-like protein
NEGILFLB_02992 1.8e-53 yhdC S Protein of unknown function (DUF3889)
NEGILFLB_02993 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NEGILFLB_02994 1e-75 nsrR K Transcriptional regulator
NEGILFLB_02995 4.8e-237 ygxB M Conserved TM helix
NEGILFLB_02996 6.3e-276 ycgB S Stage V sporulation protein R
NEGILFLB_02997 3.7e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NEGILFLB_02998 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEGILFLB_02999 9.5e-71 ywhA K Transcriptional regulator
NEGILFLB_03000 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NEGILFLB_03001 5.1e-119 ywhC S Peptidase family M50
NEGILFLB_03002 5.2e-95 ywhD S YwhD family
NEGILFLB_03003 3.6e-49
NEGILFLB_03004 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NEGILFLB_03005 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NEGILFLB_03006 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NEGILFLB_03007 2.9e-84 ywhH S Aminoacyl-tRNA editing domain
NEGILFLB_03009 4.4e-78 S aspartate phosphatase
NEGILFLB_03010 2.7e-191 ywhK CO amine dehydrogenase activity
NEGILFLB_03011 3.6e-244 ywhL CO amine dehydrogenase activity
NEGILFLB_03013 8.6e-248 L Peptidase, M16
NEGILFLB_03014 1.2e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
NEGILFLB_03015 1.5e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NEGILFLB_03016 3.3e-132 cbiO V ABC transporter
NEGILFLB_03018 4.9e-270 C Fe-S oxidoreductases
NEGILFLB_03019 1e-07 S Bacteriocin subtilosin A
NEGILFLB_03020 4.7e-73 ywiB S protein conserved in bacteria
NEGILFLB_03021 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NEGILFLB_03022 1.3e-213 narK P COG2223 Nitrate nitrite transporter
NEGILFLB_03023 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NEGILFLB_03024 2.6e-137 ywiC S YwiC-like protein
NEGILFLB_03025 3.8e-84 arfM T cyclic nucleotide binding
NEGILFLB_03026 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEGILFLB_03027 5.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
NEGILFLB_03028 2.8e-94 narJ 1.7.5.1 C nitrate reductase
NEGILFLB_03029 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
NEGILFLB_03030 1.2e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEGILFLB_03031 0.0 ywjA V ABC transporter
NEGILFLB_03032 4.8e-96 ywjB H RibD C-terminal domain
NEGILFLB_03033 2.7e-42 ywjC
NEGILFLB_03034 1.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NEGILFLB_03035 7.8e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NEGILFLB_03036 0.0 fadF C COG0247 Fe-S oxidoreductase
NEGILFLB_03037 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NEGILFLB_03038 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NEGILFLB_03039 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEGILFLB_03040 1.8e-90 ywjG S Domain of unknown function (DUF2529)
NEGILFLB_03041 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NEGILFLB_03042 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NEGILFLB_03043 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NEGILFLB_03044 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEGILFLB_03045 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NEGILFLB_03046 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEGILFLB_03047 1.1e-32 rpmE J Binds the 23S rRNA
NEGILFLB_03048 7e-104 tdk 2.7.1.21 F thymidine kinase
NEGILFLB_03049 9.7e-281 pbpA 3.4.16.4 M penicillin-binding protein
NEGILFLB_03050 6.9e-143 pstS P Phosphate
NEGILFLB_03051 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NEGILFLB_03052 2.2e-157 pstA P Phosphate transport system permease
NEGILFLB_03053 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEGILFLB_03054 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEGILFLB_03055 7.3e-72 yqzC S YceG-like family
NEGILFLB_03056 9.2e-51 yqzD
NEGILFLB_03058 1.2e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NEGILFLB_03059 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NEGILFLB_03060 3.9e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NEGILFLB_03061 2.5e-09 yqgO
NEGILFLB_03062 8.1e-237 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NEGILFLB_03063 4.3e-33 yqgQ S Protein conserved in bacteria
NEGILFLB_03064 4.4e-180 glcK 2.7.1.2 G Glucokinase
NEGILFLB_03065 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NEGILFLB_03066 1.8e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NEGILFLB_03067 3e-198 yqgU
NEGILFLB_03068 6.9e-50 yqgV S Thiamine-binding protein
NEGILFLB_03069 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NEGILFLB_03070 1.8e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NEGILFLB_03071 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NEGILFLB_03072 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NEGILFLB_03074 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NEGILFLB_03075 1.5e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NEGILFLB_03076 5.2e-173 corA P Mg2 transporter protein
NEGILFLB_03077 4.6e-07 ylbB S IMP dehydrogenase activity
NEGILFLB_03078 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NEGILFLB_03079 1.9e-173 comGB NU COG1459 Type II secretory pathway, component PulF
NEGILFLB_03080 4e-47 comGC U Required for transformation and DNA binding
NEGILFLB_03081 1.8e-69 gspH NU protein transport across the cell outer membrane
NEGILFLB_03082 1.2e-58 comGE
NEGILFLB_03083 2e-35 comGF U Putative Competence protein ComGF
NEGILFLB_03084 1.2e-43 S ComG operon protein 7
NEGILFLB_03085 5.2e-26 yqzE S YqzE-like protein
NEGILFLB_03086 2.6e-52 yqzG S Protein of unknown function (DUF3889)
NEGILFLB_03087 3.2e-109 yqxM
NEGILFLB_03088 6.7e-59 sipW 3.4.21.89 U Signal peptidase
NEGILFLB_03089 8.6e-142 tasA S Cell division protein FtsN
NEGILFLB_03090 1e-54 sinR K transcriptional
NEGILFLB_03091 3.6e-24 sinI S Anti-repressor SinI
NEGILFLB_03092 1e-150 yqhG S Bacterial protein YqhG of unknown function
NEGILFLB_03093 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NEGILFLB_03094 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NEGILFLB_03095 4.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NEGILFLB_03096 2e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NEGILFLB_03097 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NEGILFLB_03098 1.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NEGILFLB_03099 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NEGILFLB_03100 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
NEGILFLB_03101 2.2e-61 yqhP
NEGILFLB_03102 1.4e-173 yqhQ S Protein of unknown function (DUF1385)
NEGILFLB_03103 2.3e-93 yqhR S Conserved membrane protein YqhR
NEGILFLB_03104 5.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NEGILFLB_03105 5.7e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NEGILFLB_03106 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEGILFLB_03107 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NEGILFLB_03108 1.5e-169 spoIIIAA S stage III sporulation protein AA
NEGILFLB_03109 4.1e-84 spoIIIAB S Stage III sporulation protein
NEGILFLB_03110 7.6e-29 spoIIIAC S stage III sporulation protein AC
NEGILFLB_03111 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NEGILFLB_03112 1.3e-197 spoIIIAE S stage III sporulation protein AE
NEGILFLB_03113 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NEGILFLB_03114 6.9e-103 spoIIIAG S stage III sporulation protein AG
NEGILFLB_03115 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NEGILFLB_03116 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEGILFLB_03117 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NEGILFLB_03118 2.1e-67 yqhY S protein conserved in bacteria
NEGILFLB_03119 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEGILFLB_03120 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEGILFLB_03121 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEGILFLB_03122 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEGILFLB_03123 8.5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NEGILFLB_03124 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEGILFLB_03125 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NEGILFLB_03126 5.6e-77 argR K Regulates arginine biosynthesis genes
NEGILFLB_03127 5.5e-306 recN L May be involved in recombinational repair of damaged DNA
NEGILFLB_03128 4e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
NEGILFLB_03129 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NEGILFLB_03131 2.1e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NEGILFLB_03132 6e-27
NEGILFLB_03133 1.2e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NEGILFLB_03134 1.2e-129 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NEGILFLB_03135 1.9e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
NEGILFLB_03136 6.3e-154 hbdA 1.1.1.157 I Dehydrogenase
NEGILFLB_03137 6.3e-210 mmgC I acyl-CoA dehydrogenase
NEGILFLB_03138 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NEGILFLB_03139 1.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NEGILFLB_03140 3.9e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NEGILFLB_03141 4e-34 yqzF S Protein of unknown function (DUF2627)
NEGILFLB_03142 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NEGILFLB_03143 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NEGILFLB_03144 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NEGILFLB_03145 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NEGILFLB_03146 1.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NEGILFLB_03147 4.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NEGILFLB_03148 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NEGILFLB_03149 3.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEGILFLB_03150 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NEGILFLB_03151 7.9e-208 norA EGP Major facilitator Superfamily
NEGILFLB_03152 3.5e-163 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NEGILFLB_03153 9.3e-77 yqiW S Belongs to the UPF0403 family
NEGILFLB_03154 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NEGILFLB_03155 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NEGILFLB_03156 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NEGILFLB_03157 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
NEGILFLB_03158 2.6e-97 yqjB S protein conserved in bacteria
NEGILFLB_03160 1.9e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NEGILFLB_03161 5.9e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NEGILFLB_03162 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NEGILFLB_03163 7.5e-136 yqjF S Uncharacterized conserved protein (COG2071)
NEGILFLB_03164 1.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEGILFLB_03165 4.5e-24 yqzJ
NEGILFLB_03166 1.1e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEGILFLB_03167 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEGILFLB_03168 3.3e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEGILFLB_03169 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEGILFLB_03170 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NEGILFLB_03171 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NEGILFLB_03172 1.2e-191 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NEGILFLB_03173 0.0 rocB E arginine degradation protein
NEGILFLB_03174 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEGILFLB_03175 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NEGILFLB_03176 2.9e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_03177 5.4e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NEGILFLB_03178 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NEGILFLB_03179 4.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEGILFLB_03181 7e-223 yqjV G Major Facilitator Superfamily
NEGILFLB_03183 2.7e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEGILFLB_03184 5.7e-50 S YolD-like protein
NEGILFLB_03185 3.6e-87 yqjY K acetyltransferase
NEGILFLB_03186 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NEGILFLB_03187 7.5e-194 yqkA K GrpB protein
NEGILFLB_03188 2.8e-54 yqkB S Belongs to the HesB IscA family
NEGILFLB_03189 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NEGILFLB_03190 1.4e-170 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NEGILFLB_03191 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NEGILFLB_03192 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NEGILFLB_03194 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NEGILFLB_03195 2.6e-219 yqxK 3.6.4.12 L DNA helicase
NEGILFLB_03196 4.5e-58 ansR K Transcriptional regulator
NEGILFLB_03197 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NEGILFLB_03198 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NEGILFLB_03199 9.1e-235 mleN C Na H antiporter
NEGILFLB_03200 5.5e-242 mleA 1.1.1.38 C malic enzyme
NEGILFLB_03201 2.1e-29 yqkK
NEGILFLB_03202 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NEGILFLB_03203 2.4e-80 fur P Belongs to the Fur family
NEGILFLB_03204 3.7e-37 S Protein of unknown function (DUF4227)
NEGILFLB_03205 9.7e-166 xerD L recombinase XerD
NEGILFLB_03206 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NEGILFLB_03207 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NEGILFLB_03208 2e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NEGILFLB_03209 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NEGILFLB_03210 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NEGILFLB_03211 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEGILFLB_03212 9.6e-112 spoVAA S Stage V sporulation protein AA
NEGILFLB_03213 1e-67 spoVAB S Stage V sporulation protein AB
NEGILFLB_03214 2.3e-78 spoVAC S stage V sporulation protein AC
NEGILFLB_03215 9e-192 spoVAD I Stage V sporulation protein AD
NEGILFLB_03216 2.2e-57 spoVAEB S stage V sporulation protein
NEGILFLB_03217 1.4e-110 spoVAEA S stage V sporulation protein
NEGILFLB_03218 1.4e-273 spoVAF EG Stage V sporulation protein AF
NEGILFLB_03219 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEGILFLB_03220 8.1e-149 ypuA S Secreted protein
NEGILFLB_03221 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEGILFLB_03223 1.6e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NEGILFLB_03224 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NEGILFLB_03225 7.8e-55 ypuD
NEGILFLB_03226 6.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NEGILFLB_03227 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
NEGILFLB_03228 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NEGILFLB_03229 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NEGILFLB_03230 1.3e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEGILFLB_03231 9.4e-92 ypuF S Domain of unknown function (DUF309)
NEGILFLB_03232 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEGILFLB_03233 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEGILFLB_03234 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NEGILFLB_03235 1e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NEGILFLB_03236 3.5e-103 spmA S Spore maturation protein
NEGILFLB_03237 1.9e-87 spmB S Spore maturation protein
NEGILFLB_03238 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NEGILFLB_03239 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NEGILFLB_03240 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NEGILFLB_03241 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NEGILFLB_03242 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_03243 0.0 resE 2.7.13.3 T Histidine kinase
NEGILFLB_03244 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_03245 1.8e-185 rsiX
NEGILFLB_03246 9.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NEGILFLB_03247 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEGILFLB_03248 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEGILFLB_03249 4.7e-41 fer C Ferredoxin
NEGILFLB_03250 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
NEGILFLB_03251 9.2e-286 recQ 3.6.4.12 L DNA helicase
NEGILFLB_03252 1.1e-99 ypbD S metal-dependent membrane protease
NEGILFLB_03253 2.2e-78 ypbE M Lysin motif
NEGILFLB_03254 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NEGILFLB_03255 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NEGILFLB_03256 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NEGILFLB_03257 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NEGILFLB_03258 8.7e-176 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NEGILFLB_03259 2.5e-231 yqgE EGP Major facilitator superfamily
NEGILFLB_03260 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NEGILFLB_03261 4e-73 yqgC S protein conserved in bacteria
NEGILFLB_03262 3.9e-131 yqgB S Protein of unknown function (DUF1189)
NEGILFLB_03263 4.9e-45 yqfZ M LysM domain
NEGILFLB_03264 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NEGILFLB_03265 4.3e-62 yqfX S membrane
NEGILFLB_03266 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NEGILFLB_03267 1.9e-77 zur P Belongs to the Fur family
NEGILFLB_03268 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NEGILFLB_03269 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NEGILFLB_03270 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEGILFLB_03271 1.5e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NEGILFLB_03272 5.4e-13 yqfQ S YqfQ-like protein
NEGILFLB_03273 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NEGILFLB_03274 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEGILFLB_03275 1.7e-114 trmK 2.1.1.217 S SAM-dependent methyltransferase
NEGILFLB_03276 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NEGILFLB_03277 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEGILFLB_03278 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEGILFLB_03279 7.7e-88 yaiI S Belongs to the UPF0178 family
NEGILFLB_03280 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NEGILFLB_03281 4.5e-112 ccpN K CBS domain
NEGILFLB_03282 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NEGILFLB_03283 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NEGILFLB_03284 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
NEGILFLB_03285 8.4e-19 S YqzL-like protein
NEGILFLB_03286 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEGILFLB_03287 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NEGILFLB_03288 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NEGILFLB_03289 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEGILFLB_03290 0.0 yqfF S membrane-associated HD superfamily hydrolase
NEGILFLB_03292 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NEGILFLB_03293 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NEGILFLB_03294 2.7e-45 yqfC S sporulation protein YqfC
NEGILFLB_03295 5.1e-24 yqfB
NEGILFLB_03296 4.3e-122 yqfA S UPF0365 protein
NEGILFLB_03297 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NEGILFLB_03298 2.5e-61 yqeY S Yqey-like protein
NEGILFLB_03299 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NEGILFLB_03300 4.1e-157 yqeW P COG1283 Na phosphate symporter
NEGILFLB_03301 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NEGILFLB_03302 2.1e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEGILFLB_03303 4.6e-174 prmA J Methylates ribosomal protein L11
NEGILFLB_03304 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEGILFLB_03305 0.0 dnaK O Heat shock 70 kDa protein
NEGILFLB_03306 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEGILFLB_03307 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEGILFLB_03308 7.7e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
NEGILFLB_03309 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEGILFLB_03310 1e-51 yqxA S Protein of unknown function (DUF3679)
NEGILFLB_03311 1.5e-222 spoIIP M stage II sporulation protein P
NEGILFLB_03312 1.5e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NEGILFLB_03313 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NEGILFLB_03314 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NEGILFLB_03315 4.1e-15 S YqzM-like protein
NEGILFLB_03316 0.0 comEC S Competence protein ComEC
NEGILFLB_03317 8e-105 comEB 3.5.4.12 F ComE operon protein 2
NEGILFLB_03318 1e-97 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NEGILFLB_03319 1.6e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEGILFLB_03320 4.2e-138 yqeM Q Methyltransferase
NEGILFLB_03321 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEGILFLB_03322 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NEGILFLB_03323 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEGILFLB_03324 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NEGILFLB_03325 6.6e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEGILFLB_03326 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NEGILFLB_03327 5.3e-95 yqeG S hydrolase of the HAD superfamily
NEGILFLB_03329 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NEGILFLB_03330 2.3e-136 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NEGILFLB_03331 6.7e-105 yqeD S SNARE associated Golgi protein
NEGILFLB_03332 1.4e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NEGILFLB_03333 5.7e-132 yqeB
NEGILFLB_03334 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NEGILFLB_03335 2.7e-10 S SR1 protein
NEGILFLB_03336 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NEGILFLB_03337 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NEGILFLB_03338 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEGILFLB_03339 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NEGILFLB_03340 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NEGILFLB_03341 1.1e-107 recN L Putative cell-wall binding lipoprotein
NEGILFLB_03343 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEGILFLB_03344 5.5e-147 ykrA S hydrolases of the HAD superfamily
NEGILFLB_03345 8.2e-31 ykzG S Belongs to the UPF0356 family
NEGILFLB_03346 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEGILFLB_03347 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NEGILFLB_03348 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NEGILFLB_03349 1.1e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NEGILFLB_03350 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NEGILFLB_03351 1.5e-43 abrB K of stationary sporulation gene expression
NEGILFLB_03352 7.7e-183 mreB D Rod-share determining protein MreBH
NEGILFLB_03353 1.1e-12 S Uncharacterized protein YkpC
NEGILFLB_03354 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NEGILFLB_03355 6.9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEGILFLB_03356 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NEGILFLB_03357 8.1e-39 ykoA
NEGILFLB_03358 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NEGILFLB_03359 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NEGILFLB_03360 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NEGILFLB_03361 3.1e-136 fruR K Transcriptional regulator
NEGILFLB_03362 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NEGILFLB_03363 1.6e-123 macB V ABC transporter, ATP-binding protein
NEGILFLB_03364 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEGILFLB_03365 2.9e-117 yknW S Yip1 domain
NEGILFLB_03367 1.1e-07 S Uncharacterized protein pXO2-11
NEGILFLB_03368 2.4e-32
NEGILFLB_03369 4.9e-175 trsE S AAA-like domain
NEGILFLB_03371 1e-55 M Lysozyme-like
NEGILFLB_03372 2.6e-08
NEGILFLB_03375 1.1e-90 S COG0790 FOG TPR repeat, SEL1 subfamily
NEGILFLB_03377 8.5e-76 L Protein of unknown function (DUF3991)
NEGILFLB_03381 3.5e-14 S Repressor of ComK
NEGILFLB_03382 4.3e-42 L Site-specific recombinase, phage integrase family
NEGILFLB_03384 5e-20 S Domain of unknown function (DUF4062)
NEGILFLB_03388 3.3e-121 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
NEGILFLB_03389 2.3e-17
NEGILFLB_03391 4.2e-36 3.1.31.1 L COG1525 Micrococcal nuclease (thermonuclease) homologs
NEGILFLB_03393 6e-211 yttB EGP Major facilitator Superfamily
NEGILFLB_03394 1.1e-42 yttA 2.7.13.3 S Pfam Transposase IS66
NEGILFLB_03395 0.0 bceB V ABC transporter (permease)
NEGILFLB_03396 1.1e-138 bceA V ABC transporter, ATP-binding protein
NEGILFLB_03397 1.1e-181 T PhoQ Sensor
NEGILFLB_03398 4.4e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEGILFLB_03399 3.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NEGILFLB_03400 6.5e-125 ytrE V ABC transporter, ATP-binding protein
NEGILFLB_03401 2.4e-149
NEGILFLB_03402 2e-164 P ABC-2 family transporter protein
NEGILFLB_03403 4.2e-161 ytrB P abc transporter atp-binding protein
NEGILFLB_03404 5.1e-66 ytrA K GntR family transcriptional regulator
NEGILFLB_03406 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NEGILFLB_03407 4e-189 yhcC S Fe-S oxidoreductase
NEGILFLB_03408 3.7e-105 ytqB J Putative rRNA methylase
NEGILFLB_03409 5.7e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NEGILFLB_03410 4.2e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NEGILFLB_03411 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NEGILFLB_03412 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NEGILFLB_03413 0.0 asnB 6.3.5.4 E Asparagine synthase
NEGILFLB_03414 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEGILFLB_03415 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NEGILFLB_03416 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NEGILFLB_03417 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NEGILFLB_03418 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NEGILFLB_03419 1.4e-144 ytlC P ABC transporter
NEGILFLB_03420 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NEGILFLB_03421 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NEGILFLB_03422 7e-63 ytkC S Bacteriophage holin family
NEGILFLB_03423 2.1e-76 dps P Belongs to the Dps family
NEGILFLB_03425 1.1e-72 ytkA S YtkA-like
NEGILFLB_03426 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEGILFLB_03427 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NEGILFLB_03428 3.6e-41 rpmE2 J Ribosomal protein L31
NEGILFLB_03429 1.8e-248 cydA 1.10.3.14 C oxidase, subunit
NEGILFLB_03430 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NEGILFLB_03431 1.1e-24 S Domain of Unknown Function (DUF1540)
NEGILFLB_03432 1.3e-149 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NEGILFLB_03433 7.4e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NEGILFLB_03434 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NEGILFLB_03435 2e-169 troA P Belongs to the bacterial solute-binding protein 9 family
NEGILFLB_03436 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NEGILFLB_03437 3e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NEGILFLB_03438 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NEGILFLB_03439 1.9e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NEGILFLB_03440 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NEGILFLB_03441 9.4e-272 menF 5.4.4.2 HQ Isochorismate synthase
NEGILFLB_03442 2.6e-132 dksA T COG1734 DnaK suppressor protein
NEGILFLB_03443 2.8e-151 galU 2.7.7.9 M Nucleotidyl transferase
NEGILFLB_03444 5.4e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEGILFLB_03445 4.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NEGILFLB_03446 8.2e-232 ytcC M Glycosyltransferase Family 4
NEGILFLB_03448 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
NEGILFLB_03449 2.6e-216 cotSA M Glycosyl transferases group 1
NEGILFLB_03450 1.7e-204 cotI S Spore coat protein
NEGILFLB_03451 3.2e-75 tspO T membrane
NEGILFLB_03452 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEGILFLB_03453 5.5e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NEGILFLB_03454 4.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NEGILFLB_03455 2.3e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEGILFLB_03456 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEGILFLB_03458 8.3e-121 ykwD J protein with SCP PR1 domains
NEGILFLB_03459 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NEGILFLB_03460 0.0 pilS 2.7.13.3 T Histidine kinase
NEGILFLB_03461 1.5e-222 patA 2.6.1.1 E Aminotransferase
NEGILFLB_03462 1.3e-15
NEGILFLB_03463 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NEGILFLB_03464 1.7e-84 ykyB S YkyB-like protein
NEGILFLB_03465 2.8e-238 ykuC EGP Major facilitator Superfamily
NEGILFLB_03466 1.8e-87 ykuD S protein conserved in bacteria
NEGILFLB_03467 9.4e-166 ykuE S Metallophosphoesterase
NEGILFLB_03468 8.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_03469 2e-233 ykuI T Diguanylate phosphodiesterase
NEGILFLB_03470 3.9e-37 ykuJ S protein conserved in bacteria
NEGILFLB_03471 4.4e-94 ykuK S Ribonuclease H-like
NEGILFLB_03472 3.9e-27 ykzF S Antirepressor AbbA
NEGILFLB_03473 1.6e-76 ykuL S CBS domain
NEGILFLB_03474 3.5e-168 ccpC K Transcriptional regulator
NEGILFLB_03475 1.7e-84 fld C Flavodoxin domain
NEGILFLB_03476 1.5e-174 ykuO
NEGILFLB_03477 3.9e-78 fld C Flavodoxin
NEGILFLB_03478 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NEGILFLB_03479 2.1e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NEGILFLB_03480 9e-37 ykuS S Belongs to the UPF0180 family
NEGILFLB_03481 8.8e-142 ykuT M Mechanosensitive ion channel
NEGILFLB_03482 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NEGILFLB_03483 1.4e-80 ykuV CO thiol-disulfide
NEGILFLB_03484 1.5e-93 rok K Repressor of ComK
NEGILFLB_03485 2.1e-145 yknT
NEGILFLB_03486 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NEGILFLB_03487 2.2e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NEGILFLB_03488 1.5e-244 moeA 2.10.1.1 H molybdopterin
NEGILFLB_03489 3.2e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NEGILFLB_03490 1.4e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NEGILFLB_03491 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NEGILFLB_03492 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NEGILFLB_03493 6.6e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NEGILFLB_03494 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NEGILFLB_03495 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NEGILFLB_03496 2.1e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NEGILFLB_03497 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NEGILFLB_03498 9.3e-62 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NEGILFLB_03499 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NEGILFLB_03500 8.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NEGILFLB_03501 2.1e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NEGILFLB_03502 2.9e-176 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NEGILFLB_03503 3.2e-71 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEGILFLB_03504 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEGILFLB_03505 1e-224 rasP M zinc metalloprotease
NEGILFLB_03506 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NEGILFLB_03507 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NEGILFLB_03508 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEGILFLB_03509 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEGILFLB_03510 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NEGILFLB_03511 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEGILFLB_03512 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NEGILFLB_03513 4.8e-77 ylxL
NEGILFLB_03514 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEGILFLB_03515 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NEGILFLB_03516 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NEGILFLB_03517 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NEGILFLB_03518 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NEGILFLB_03519 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NEGILFLB_03520 2.8e-157 flhG D Belongs to the ParA family
NEGILFLB_03521 2e-200 flhF N Flagellar biosynthesis regulator FlhF
NEGILFLB_03522 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NEGILFLB_03523 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NEGILFLB_03524 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NEGILFLB_03525 2.2e-36 fliQ N Role in flagellar biosynthesis
NEGILFLB_03526 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NEGILFLB_03527 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
NEGILFLB_03528 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NEGILFLB_03529 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NEGILFLB_03530 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NEGILFLB_03531 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NEGILFLB_03532 8.2e-140 flgG N Flagellar basal body rod
NEGILFLB_03533 1.7e-72 flgD N Flagellar basal body rod modification protein
NEGILFLB_03534 1.1e-214 fliK N Flagellar hook-length control protein
NEGILFLB_03535 5.5e-35 ylxF S MgtE intracellular N domain
NEGILFLB_03536 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NEGILFLB_03537 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NEGILFLB_03538 3.7e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NEGILFLB_03539 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NEGILFLB_03540 7e-255 fliF N The M ring may be actively involved in energy transduction
NEGILFLB_03541 1.9e-31 fliE N Flagellar hook-basal body
NEGILFLB_03542 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
NEGILFLB_03543 1.5e-62 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NEGILFLB_03544 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NEGILFLB_03545 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NEGILFLB_03546 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NEGILFLB_03547 2.5e-169 xerC L tyrosine recombinase XerC
NEGILFLB_03548 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NEGILFLB_03549 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEGILFLB_03550 1e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NEGILFLB_03551 1.2e-166 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NEGILFLB_03552 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NEGILFLB_03553 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NEGILFLB_03554 1.8e-288 ylqG
NEGILFLB_03555 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEGILFLB_03556 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NEGILFLB_03557 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEGILFLB_03558 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NEGILFLB_03559 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEGILFLB_03560 6.3e-61 ylqD S YlqD protein
NEGILFLB_03561 4.5e-36 ylqC S Belongs to the UPF0109 family
NEGILFLB_03562 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NEGILFLB_03563 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEGILFLB_03564 2.1e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NEGILFLB_03565 2.9e-87
NEGILFLB_03566 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEGILFLB_03567 0.0 smc D Required for chromosome condensation and partitioning
NEGILFLB_03568 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEGILFLB_03569 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEGILFLB_03570 2.3e-128 IQ reductase
NEGILFLB_03571 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NEGILFLB_03572 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEGILFLB_03573 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NEGILFLB_03574 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEGILFLB_03575 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NEGILFLB_03576 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NEGILFLB_03577 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
NEGILFLB_03578 5.5e-59 asp S protein conserved in bacteria
NEGILFLB_03579 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NEGILFLB_03580 4.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
NEGILFLB_03581 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NEGILFLB_03582 1.9e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEGILFLB_03583 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NEGILFLB_03584 1.6e-140 stp 3.1.3.16 T phosphatase
NEGILFLB_03585 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NEGILFLB_03586 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEGILFLB_03587 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEGILFLB_03588 1.5e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEGILFLB_03589 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEGILFLB_03590 4.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEGILFLB_03591 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEGILFLB_03592 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NEGILFLB_03593 1.5e-40 ylzA S Belongs to the UPF0296 family
NEGILFLB_03594 2.4e-156 yloC S stress-induced protein
NEGILFLB_03595 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NEGILFLB_03596 4e-100 S aspartate phosphatase
NEGILFLB_03598 6.9e-19
NEGILFLB_03599 1.5e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NEGILFLB_03600 3.3e-89 yokH G SMI1 / KNR4 family
NEGILFLB_03601 1.5e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NEGILFLB_03602 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NEGILFLB_03603 3.6e-134 yobQ K helix_turn_helix, arabinose operon control protein
NEGILFLB_03604 5.3e-141 yobR 2.3.1.1 J FR47-like protein
NEGILFLB_03605 3.6e-97 yobS K Transcriptional regulator
NEGILFLB_03606 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NEGILFLB_03607 7.1e-86 yobU K Bacterial transcription activator, effector binding domain
NEGILFLB_03608 7.3e-172 yobV K WYL domain
NEGILFLB_03609 8.8e-93 yobW
NEGILFLB_03610 1e-51 czrA K transcriptional
NEGILFLB_03611 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NEGILFLB_03612 1.5e-92 yozB S membrane
NEGILFLB_03613 6.4e-145
NEGILFLB_03614 6.1e-93 yocC
NEGILFLB_03615 9.3e-186 yocD 3.4.17.13 V peptidase S66
NEGILFLB_03616 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NEGILFLB_03617 7.1e-198 desK 2.7.13.3 T Histidine kinase
NEGILFLB_03618 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEGILFLB_03619 1.7e-111 yocH CBM50 M COG1388 FOG LysM repeat
NEGILFLB_03620 0.0 recQ 3.6.4.12 L DNA helicase
NEGILFLB_03621 1.8e-184 appD P Belongs to the ABC transporter superfamily
NEGILFLB_03622 1.4e-184 appF E Belongs to the ABC transporter superfamily
NEGILFLB_03623 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NEGILFLB_03624 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEGILFLB_03625 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEGILFLB_03626 5e-147 yjbA S Belongs to the UPF0736 family
NEGILFLB_03627 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NEGILFLB_03628 2e-68 psiE S Protein PsiE homolog
NEGILFLB_03629 1.7e-235 yrkQ T Histidine kinase
NEGILFLB_03630 3.5e-126 T Transcriptional regulator
NEGILFLB_03631 1.4e-223 yrkO P Protein of unknown function (DUF418)
NEGILFLB_03632 2.3e-104 yrkN K Acetyltransferase (GNAT) family
NEGILFLB_03633 1.6e-96 ywrO S Flavodoxin-like fold
NEGILFLB_03634 2.8e-79 S Protein of unknown function with HXXEE motif
NEGILFLB_03635 9.7e-101 yrkJ S membrane transporter protein
NEGILFLB_03636 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NEGILFLB_03637 2.9e-199 yrkH P Rhodanese Homology Domain
NEGILFLB_03638 7e-93 yrkF OP Belongs to the sulfur carrier protein TusA family
NEGILFLB_03639 2.6e-45 P Rhodanese Homology Domain
NEGILFLB_03640 1.4e-81 yrkE O DsrE/DsrF/DrsH-like family
NEGILFLB_03641 7.8e-39 yrkD S protein conserved in bacteria
NEGILFLB_03642 2.5e-103 yrkC G Cupin domain
NEGILFLB_03643 1.8e-181 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEGILFLB_03644 1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEGILFLB_03645 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEGILFLB_03646 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NEGILFLB_03647 1.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEGILFLB_03648 2.7e-233 S COG0457 FOG TPR repeat
NEGILFLB_03649 1.1e-98 ypiB S Belongs to the UPF0302 family
NEGILFLB_03650 4.2e-77 ypiF S Protein of unknown function (DUF2487)
NEGILFLB_03651 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NEGILFLB_03652 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NEGILFLB_03653 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NEGILFLB_03654 9.9e-98 ypjA S membrane
NEGILFLB_03655 1e-142 ypjB S sporulation protein
NEGILFLB_03656 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NEGILFLB_03657 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NEGILFLB_03658 1.2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEGILFLB_03659 1.6e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NEGILFLB_03660 3.4e-129 bshB1 S proteins, LmbE homologs
NEGILFLB_03661 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NEGILFLB_03662 2.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NEGILFLB_03663 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEGILFLB_03664 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NEGILFLB_03665 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NEGILFLB_03666 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NEGILFLB_03667 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NEGILFLB_03668 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NEGILFLB_03669 1.1e-78 ypmB S protein conserved in bacteria
NEGILFLB_03670 8.2e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NEGILFLB_03671 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NEGILFLB_03672 5.7e-129 dnaD L DNA replication protein DnaD
NEGILFLB_03673 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEGILFLB_03674 2e-91 ypoC
NEGILFLB_03675 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NEGILFLB_03676 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NEGILFLB_03677 7.7e-185 yppC S Protein of unknown function (DUF2515)
NEGILFLB_03680 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
NEGILFLB_03682 1.2e-48 yppG S YppG-like protein
NEGILFLB_03683 8e-70 hspX O Belongs to the small heat shock protein (HSP20) family
NEGILFLB_03684 3.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NEGILFLB_03685 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NEGILFLB_03686 2.1e-235 yprB L RNase_H superfamily
NEGILFLB_03687 3.2e-95 ypsA S Belongs to the UPF0398 family
NEGILFLB_03688 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NEGILFLB_03689 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NEGILFLB_03691 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NEGILFLB_03692 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_03693 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NEGILFLB_03694 1.5e-186 ptxS K transcriptional
NEGILFLB_03695 1.9e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NEGILFLB_03696 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NEGILFLB_03697 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NEGILFLB_03698 1.9e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NEGILFLB_03699 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEGILFLB_03700 3.3e-226 pbuX F xanthine
NEGILFLB_03701 2.8e-207 bcsA Q Naringenin-chalcone synthase
NEGILFLB_03702 5.1e-87 ypbQ S protein conserved in bacteria
NEGILFLB_03703 0.0 ypbR S Dynamin family
NEGILFLB_03704 8.5e-38 ypbS S Protein of unknown function (DUF2533)
NEGILFLB_03705 2e-07
NEGILFLB_03706 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NEGILFLB_03708 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
NEGILFLB_03709 6.3e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NEGILFLB_03710 1.9e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NEGILFLB_03711 4.1e-29 ypeQ S Zinc-finger
NEGILFLB_03712 8.1e-31 S Protein of unknown function (DUF2564)
NEGILFLB_03713 3.8e-16 degR
NEGILFLB_03714 1e-30 cspD K Cold-shock protein
NEGILFLB_03715 3.5e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NEGILFLB_03716 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NEGILFLB_03717 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NEGILFLB_03718 4.4e-109 ypgQ S phosphohydrolase
NEGILFLB_03719 4.9e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
NEGILFLB_03720 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NEGILFLB_03721 1.7e-75 yphP S Belongs to the UPF0403 family
NEGILFLB_03722 1.8e-144 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NEGILFLB_03723 7.8e-114 ypjP S YpjP-like protein
NEGILFLB_03724 9.5e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NEGILFLB_03725 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEGILFLB_03726 4.5e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NEGILFLB_03727 4.2e-110 hlyIII S protein, Hemolysin III
NEGILFLB_03728 4.7e-185 pspF K Transcriptional regulator
NEGILFLB_03729 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NEGILFLB_03730 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NEGILFLB_03731 4.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NEGILFLB_03732 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NEGILFLB_03733 1.1e-98 ypmS S protein conserved in bacteria
NEGILFLB_03734 5.5e-29 ypmT S Uncharacterized ympT
NEGILFLB_03735 5.8e-223 mepA V MATE efflux family protein
NEGILFLB_03736 1.6e-70 ypoP K transcriptional
NEGILFLB_03737 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEGILFLB_03738 3.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NEGILFLB_03739 6.2e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
NEGILFLB_03740 5.4e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NEGILFLB_03741 7e-178 cgeB S Spore maturation protein
NEGILFLB_03742 3.1e-63 cgeA
NEGILFLB_03743 4.5e-38 cgeC
NEGILFLB_03744 1.9e-152 ymdB S protein conserved in bacteria
NEGILFLB_03745 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NEGILFLB_03746 9.7e-214 pbpX V Beta-lactamase
NEGILFLB_03747 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEGILFLB_03748 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
NEGILFLB_03749 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEGILFLB_03750 1.9e-124 ymfM S protein conserved in bacteria
NEGILFLB_03751 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NEGILFLB_03752 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NEGILFLB_03753 1.9e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NEGILFLB_03754 4.1e-242 ymfH S zinc protease
NEGILFLB_03755 7.8e-233 ymfF S Peptidase M16
NEGILFLB_03756 3.8e-205 ymfD EGP Major facilitator Superfamily
NEGILFLB_03757 1.4e-133 ymfC K Transcriptional regulator
NEGILFLB_03758 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NEGILFLB_03759 4.4e-32 S YlzJ-like protein
NEGILFLB_03760 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NEGILFLB_03761 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEGILFLB_03762 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEGILFLB_03763 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NEGILFLB_03764 4.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEGILFLB_03765 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NEGILFLB_03766 6.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NEGILFLB_03767 2.6e-42 ymxH S YlmC YmxH family
NEGILFLB_03768 4.4e-233 pepR S Belongs to the peptidase M16 family
NEGILFLB_03769 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NEGILFLB_03770 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NEGILFLB_03771 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEGILFLB_03772 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NEGILFLB_03773 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEGILFLB_03774 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEGILFLB_03775 3.9e-44 ylxP S protein conserved in bacteria
NEGILFLB_03776 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEGILFLB_03777 3.1e-47 ylxQ J ribosomal protein
NEGILFLB_03778 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NEGILFLB_03779 1.1e-203 nusA K Participates in both transcription termination and antitermination
NEGILFLB_03780 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NEGILFLB_03781 3.9e-13 spaC2 V PFAM Lanthionine synthetase
NEGILFLB_03782 7.8e-61
NEGILFLB_03783 1.6e-48 L Recombinase
NEGILFLB_03784 5.3e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NEGILFLB_03785 5.2e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NEGILFLB_03786 2e-79 yngA S membrane
NEGILFLB_03787 2.7e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NEGILFLB_03788 5.5e-104 yngC S membrane-associated protein
NEGILFLB_03789 8.1e-232 nrnB S phosphohydrolase (DHH superfamily)
NEGILFLB_03790 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NEGILFLB_03791 1.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NEGILFLB_03792 7.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NEGILFLB_03793 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NEGILFLB_03794 6.2e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NEGILFLB_03795 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NEGILFLB_03796 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NEGILFLB_03797 1.4e-23 S Family of unknown function (DUF5367)
NEGILFLB_03798 7.7e-304 yngK T Glycosyl hydrolase-like 10
NEGILFLB_03799 6.8e-63 yngL S Protein of unknown function (DUF1360)
NEGILFLB_03800 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NEGILFLB_03801 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_03802 7.3e-228 cypA C Cytochrome P450
NEGILFLB_03803 1.6e-52 yrdC 3.5.1.19 Q Isochorismatase family
NEGILFLB_03804 1.5e-54 S Protein of unknown function (DUF2568)
NEGILFLB_03806 3.9e-29
NEGILFLB_03807 7.2e-40
NEGILFLB_03808 6.4e-90 yrdA S DinB family
NEGILFLB_03809 5.1e-164 aadK G Streptomycin adenylyltransferase
NEGILFLB_03810 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NEGILFLB_03811 3.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NEGILFLB_03812 8.7e-125 yrpD S Domain of unknown function, YrpD
NEGILFLB_03814 7.6e-111 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NEGILFLB_03815 1e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NEGILFLB_03816 3.2e-186 yrpG C Aldo/keto reductase family
NEGILFLB_03817 3.7e-222 yraO C Citrate transporter
NEGILFLB_03818 3.7e-162 yraN K Transcriptional regulator
NEGILFLB_03820 8.3e-23
NEGILFLB_03821 3.2e-86 traC L Domain of unknown function (DUF1738)
NEGILFLB_03824 5e-142 spo0M S COG4326 Sporulation control protein
NEGILFLB_03825 1.2e-26
NEGILFLB_03826 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NEGILFLB_03827 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NEGILFLB_03829 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NEGILFLB_03830 1.6e-137 azlC E AzlC protein
NEGILFLB_03831 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NEGILFLB_03832 8.1e-225 brnQ E Component of the transport system for branched-chain amino acids
NEGILFLB_03835 3.6e-148 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
NEGILFLB_03836 1.2e-89 K Transcriptional regulator PadR-like family
NEGILFLB_03837 3.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NEGILFLB_03838 1.4e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
NEGILFLB_03839 8.7e-246 yoeA V MATE efflux family protein
NEGILFLB_03840 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NEGILFLB_03842 2.2e-96 L Integrase
NEGILFLB_03843 3e-34 yoeD G Helix-turn-helix domain
NEGILFLB_03844 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NEGILFLB_03845 3.3e-155 gltR1 K Transcriptional regulator
NEGILFLB_03846 9.4e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NEGILFLB_03847 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NEGILFLB_03848 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NEGILFLB_03849 1.3e-154 gltC K Transcriptional regulator
NEGILFLB_03850 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEGILFLB_03851 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEGILFLB_03853 4.1e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NEGILFLB_03854 8.5e-81 yncE S Protein of unknown function (DUF2691)
NEGILFLB_03855 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEGILFLB_03856 2.1e-255 iolT EGP Major facilitator Superfamily
NEGILFLB_03857 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
NEGILFLB_03858 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NEGILFLB_03859 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NEGILFLB_03860 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEGILFLB_03861 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NEGILFLB_03862 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEGILFLB_03863 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEGILFLB_03864 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
NEGILFLB_03865 4e-213 yaaH M Glycoside Hydrolase Family
NEGILFLB_03866 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NEGILFLB_03867 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NEGILFLB_03868 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NEGILFLB_03871 2.2e-168 bla 3.5.2.6 V beta-lactamase
NEGILFLB_03872 1.8e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NEGILFLB_03873 7e-77 yoaW
NEGILFLB_03874 1.3e-157 yijE EG EamA-like transporter family
NEGILFLB_03875 3.3e-158 yoaU K LysR substrate binding domain
NEGILFLB_03876 5.7e-149 yoaT S Protein of unknown function (DUF817)
NEGILFLB_03877 6e-30 yozG K Transcriptional regulator
NEGILFLB_03878 7.3e-75 yoaS S Protein of unknown function (DUF2975)
NEGILFLB_03879 7.1e-172 yoaR V vancomycin resistance protein
NEGILFLB_03880 7.3e-86
NEGILFLB_03881 6.1e-18 yoaP 3.1.3.18 K YoaP-like
NEGILFLB_03883 6.7e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
NEGILFLB_03884 1.1e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NEGILFLB_03885 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NEGILFLB_03886 5e-37 rsiV S Protein of unknown function (DUF3298)
NEGILFLB_03887 0.0 yrhL I Acyltransferase family
NEGILFLB_03888 1.2e-43 yrhK S YrhK-like protein
NEGILFLB_03889 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NEGILFLB_03890 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NEGILFLB_03891 4.2e-74 yneK S Protein of unknown function (DUF2621)
NEGILFLB_03892 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NEGILFLB_03893 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NEGILFLB_03894 7.8e-126 ccdA O cytochrome c biogenesis protein
NEGILFLB_03895 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NEGILFLB_03896 1.8e-28 yneF S UPF0154 protein
NEGILFLB_03897 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NEGILFLB_03898 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NEGILFLB_03899 1.3e-32 ynzC S UPF0291 protein
NEGILFLB_03900 4.5e-112 yneB L resolvase
NEGILFLB_03901 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NEGILFLB_03902 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEGILFLB_03903 3.2e-77 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NEGILFLB_03904 5.8e-74 yndM S Protein of unknown function (DUF2512)
NEGILFLB_03905 9.9e-135 yndL S Replication protein
NEGILFLB_03907 7.2e-308 yndJ S YndJ-like protein
NEGILFLB_03908 2.4e-115 yndH S Domain of unknown function (DUF4166)
NEGILFLB_03909 5.5e-152 yndG S DoxX-like family
NEGILFLB_03910 3e-218 gerLC S Spore germination protein
NEGILFLB_03911 1.7e-196 gerAB U Spore germination
NEGILFLB_03912 1.4e-284 gerAA EG Spore germination protein
NEGILFLB_03915 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NEGILFLB_03916 5.3e-71
NEGILFLB_03917 7.9e-25 tatA U protein secretion
NEGILFLB_03920 3.2e-133 S Domain of unknown function, YrpD
NEGILFLB_03922 4.3e-163 S Thymidylate synthase
NEGILFLB_03924 1.2e-146 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NEGILFLB_03925 7.1e-119 H Methionine biosynthesis protein MetW
NEGILFLB_03926 3.7e-93 M Glycosyltransferase like family
NEGILFLB_03927 2.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
NEGILFLB_03928 7.8e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEGILFLB_03929 0.0 rhiB IQ polyketide synthase
NEGILFLB_03930 0.0 pfaA Q Polyketide synthase of type I
NEGILFLB_03931 1.3e-96 ynaD J Acetyltransferase (GNAT) domain
NEGILFLB_03933 4.4e-73 S CAAX protease self-immunity
NEGILFLB_03934 4.7e-08 S Uncharacterised protein family (UPF0715)
NEGILFLB_03935 3.4e-22 K Cro/C1-type HTH DNA-binding domain
NEGILFLB_03938 2.6e-120 L Belongs to the 'phage' integrase family
NEGILFLB_03939 1e-32 immA E IrrE N-terminal-like domain
NEGILFLB_03940 1.2e-35 yvaO K Transcriptional
NEGILFLB_03941 2e-20
NEGILFLB_03943 3.5e-64 S Bacterial protein of unknown function (DUF961)
NEGILFLB_03944 1.1e-08
NEGILFLB_03945 8.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEGILFLB_03946 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NEGILFLB_03947 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NEGILFLB_03948 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NEGILFLB_03949 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NEGILFLB_03950 3.5e-180 yaaC S YaaC-like Protein
NEGILFLB_03951 1e-35 cisA2 L Recombinase
NEGILFLB_03952 2.1e-126 T Nacht domain
NEGILFLB_03954 5.9e-178 U TraM recognition site of TraD and TraG
NEGILFLB_03955 1.4e-90 lacR K Transcriptional regulator
NEGILFLB_03956 9.1e-29 S Agrobacterium tumefaciens protein Atu4866
NEGILFLB_03957 5.3e-91 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_03959 8.7e-58 S TraX protein
NEGILFLB_03960 1.4e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
NEGILFLB_03961 3.4e-70 Q Collagen triple helix repeat (20 copies)
NEGILFLB_03962 1.9e-25 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NEGILFLB_03963 2.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NEGILFLB_03964 1.9e-178 mcpU NT methyl-accepting chemotaxis protein
NEGILFLB_03965 1.1e-36 S Protein of unknown function (DUF4025)
NEGILFLB_03966 2.6e-13
NEGILFLB_03967 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
NEGILFLB_03968 1.6e-32 yoaF
NEGILFLB_03969 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEGILFLB_03970 9.9e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEGILFLB_03971 2.5e-275 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NEGILFLB_03972 3.1e-234 yoaB EGP Major facilitator Superfamily
NEGILFLB_03973 4.1e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NEGILFLB_03974 3.6e-132 yoxB
NEGILFLB_03975 9.2e-39 yoxC S Bacterial protein of unknown function (DUF948)
NEGILFLB_03976 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_03977 2.4e-47 S Tetratricopeptide repeat
NEGILFLB_03981 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEGILFLB_03982 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEGILFLB_03983 2.4e-33 yaaA S S4 domain
NEGILFLB_03984 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEGILFLB_03985 1.8e-37 yaaB S Domain of unknown function (DUF370)
NEGILFLB_03986 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEGILFLB_03987 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEGILFLB_03991 1.6e-16 L Psort location Cytoplasmic, score 8.96
NEGILFLB_03993 7.3e-16
NEGILFLB_03994 4.3e-70
NEGILFLB_03995 5.7e-21 S SMI1-KNR4 cell-wall
NEGILFLB_03996 1.5e-29 S SMI1 / KNR4 family
NEGILFLB_03998 1.8e-193 L nucleic acid phosphodiester bond hydrolysis
NEGILFLB_03999 8.2e-79 L nucleic acid phosphodiester bond hydrolysis
NEGILFLB_04001 1e-70 K MerR family transcriptional regulator
NEGILFLB_04002 3.3e-139 yvgN 1.1.1.346 S Reductase
NEGILFLB_04003 6.1e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
NEGILFLB_04004 1.4e-24 yoqW S Belongs to the SOS response-associated peptidase family
NEGILFLB_04005 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NEGILFLB_04006 2.7e-31 yozC
NEGILFLB_04007 4.2e-56 yozO S Bacterial PH domain
NEGILFLB_04008 1.9e-36 yocN
NEGILFLB_04009 1.1e-40 yozN
NEGILFLB_04010 2.4e-86 yocM O Belongs to the small heat shock protein (HSP20) family
NEGILFLB_04011 5.8e-30
NEGILFLB_04012 1.6e-52 yocL
NEGILFLB_04013 1.8e-205 yobL S Bacterial EndoU nuclease
NEGILFLB_04018 4.4e-284 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NEGILFLB_04019 4.2e-84 ydfH_3 K FCD
NEGILFLB_04020 1.4e-95 K Transcriptional regulator
NEGILFLB_04021 5.1e-15
NEGILFLB_04022 1.7e-55 K MerR, DNA binding
NEGILFLB_04023 1.1e-125 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NEGILFLB_04024 3.1e-150 bltR K helix_turn_helix, mercury resistance
NEGILFLB_04025 1.8e-210 blt EGP Major facilitator Superfamily
NEGILFLB_04026 9.1e-83 bltD 2.3.1.57 K FR47-like protein
NEGILFLB_04027 5.1e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NEGILFLB_04028 8.7e-16 S YrzO-like protein
NEGILFLB_04029 6e-169 yrdR EG EamA-like transporter family
NEGILFLB_04030 3.9e-159 yrdQ K Transcriptional regulator
NEGILFLB_04031 3.3e-197 trkA P Oxidoreductase
NEGILFLB_04032 7.7e-153 czcD P COG1230 Co Zn Cd efflux system component
NEGILFLB_04033 2.3e-11
NEGILFLB_04034 3.2e-24
NEGILFLB_04036 1.4e-118 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NEGILFLB_04037 8.3e-44 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NEGILFLB_04038 3.8e-162 citR K Transcriptional regulator
NEGILFLB_04039 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)