ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKALJCNE_00001 5.9e-29 copZ P Copper resistance protein CopZ
HKALJCNE_00002 2.2e-48 csoR S transcriptional
HKALJCNE_00003 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
HKALJCNE_00004 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKALJCNE_00005 0.0 yvaC S Fusaric acid resistance protein-like
HKALJCNE_00006 2.8e-72 yvaD S Family of unknown function (DUF5360)
HKALJCNE_00007 3.4e-53 yvaE P Small Multidrug Resistance protein
HKALJCNE_00008 3.3e-98 K Bacterial regulatory proteins, tetR family
HKALJCNE_00009 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_00010 1.8e-15
HKALJCNE_00013 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HKALJCNE_00014 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKALJCNE_00015 5.6e-143 est 3.1.1.1 S Carboxylesterase
HKALJCNE_00016 2.4e-23 secG U Preprotein translocase subunit SecG
HKALJCNE_00017 7.7e-151 yvaM S Serine aminopeptidase, S33
HKALJCNE_00018 9.8e-36 yvzC K Transcriptional
HKALJCNE_00019 1.2e-68 K transcriptional
HKALJCNE_00020 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
HKALJCNE_00021 2.2e-54 yodB K transcriptional
HKALJCNE_00022 3.2e-218 NT chemotaxis protein
HKALJCNE_00023 2.3e-153 T His Kinase A (phosphoacceptor) domain
HKALJCNE_00024 2.5e-105 K Transcriptional regulatory protein, C terminal
HKALJCNE_00025 1.7e-81 mutG S ABC-2 family transporter protein
HKALJCNE_00026 1.5e-87 spaE S ABC-2 family transporter protein
HKALJCNE_00027 4.2e-103 mutF V ABC transporter, ATP-binding protein
HKALJCNE_00029 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
HKALJCNE_00030 2.4e-96 spaC2 V PFAM Lanthionine synthetase
HKALJCNE_00031 1.7e-156 spaT V ABC transporter
HKALJCNE_00032 4.1e-195 spaB S Lantibiotic dehydratase, C terminus
HKALJCNE_00033 4.7e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKALJCNE_00034 1.4e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKALJCNE_00035 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKALJCNE_00036 1.8e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKALJCNE_00037 3.3e-60 yvbF K Belongs to the GbsR family
HKALJCNE_00038 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKALJCNE_00039 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKALJCNE_00040 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKALJCNE_00041 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKALJCNE_00042 3.5e-97 yvbF K Belongs to the GbsR family
HKALJCNE_00043 6.4e-103 yvbG U UPF0056 membrane protein
HKALJCNE_00044 1.9e-112 yvbH S YvbH-like oligomerisation region
HKALJCNE_00045 1.4e-122 exoY M Membrane
HKALJCNE_00046 0.0 tcaA S response to antibiotic
HKALJCNE_00047 1.1e-80 yvbK 3.1.3.25 K acetyltransferase
HKALJCNE_00048 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKALJCNE_00049 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HKALJCNE_00050 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKALJCNE_00051 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKALJCNE_00052 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKALJCNE_00053 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKALJCNE_00054 1.6e-252 araE EGP Major facilitator Superfamily
HKALJCNE_00055 5.5e-203 araR K transcriptional
HKALJCNE_00056 4.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKALJCNE_00057 1.5e-158 yvbU K Transcriptional regulator
HKALJCNE_00058 2.7e-155 yvbV EG EamA-like transporter family
HKALJCNE_00059 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HKALJCNE_00060 4.9e-193 yvbX S Glycosyl hydrolase
HKALJCNE_00061 7.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKALJCNE_00062 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HKALJCNE_00063 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKALJCNE_00064 7.7e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKALJCNE_00065 1.5e-192 desK 2.7.13.3 T Histidine kinase
HKALJCNE_00066 6.9e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HKALJCNE_00067 2e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HKALJCNE_00069 4.4e-157 rsbQ S Alpha/beta hydrolase family
HKALJCNE_00070 2.4e-199 rsbU 3.1.3.3 T response regulator
HKALJCNE_00071 9.8e-252 galA 3.2.1.89 G arabinogalactan
HKALJCNE_00072 0.0 lacA 3.2.1.23 G beta-galactosidase
HKALJCNE_00073 7.2e-150 ganQ P transport
HKALJCNE_00074 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HKALJCNE_00075 2.3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
HKALJCNE_00076 1.4e-184 lacR K Transcriptional regulator
HKALJCNE_00077 1e-112 yvfI K COG2186 Transcriptional regulators
HKALJCNE_00078 1.3e-307 yvfH C L-lactate permease
HKALJCNE_00079 2.7e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HKALJCNE_00080 1e-31 yvfG S YvfG protein
HKALJCNE_00081 3e-184 yvfF GM Exopolysaccharide biosynthesis protein
HKALJCNE_00082 8.4e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HKALJCNE_00083 4.6e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HKALJCNE_00084 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKALJCNE_00085 2.9e-255 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKALJCNE_00086 2.8e-196 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HKALJCNE_00087 9.2e-203 epsI GM pyruvyl transferase
HKALJCNE_00088 2.2e-193 epsH GT2 S Glycosyltransferase like family 2
HKALJCNE_00089 1.8e-206 epsG S EpsG family
HKALJCNE_00090 7.1e-217 epsF GT4 M Glycosyl transferases group 1
HKALJCNE_00091 9.2e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKALJCNE_00092 1.2e-219 epsD GT4 M Glycosyl transferase 4-like
HKALJCNE_00093 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HKALJCNE_00094 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HKALJCNE_00095 3.4e-121 ywqC M biosynthesis protein
HKALJCNE_00096 2.8e-76 slr K transcriptional
HKALJCNE_00097 1.7e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HKALJCNE_00099 4.6e-93 padC Q Phenolic acid decarboxylase
HKALJCNE_00100 6.1e-71 MA20_18690 S Protein of unknown function (DUF3237)
HKALJCNE_00101 1.2e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HKALJCNE_00102 1.7e-262 pbpE V Beta-lactamase
HKALJCNE_00103 9.3e-66
HKALJCNE_00104 1.7e-273 sacB 2.4.1.10 GH68 M levansucrase activity
HKALJCNE_00105 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HKALJCNE_00106 3e-295 yveA E amino acid
HKALJCNE_00107 9.7e-106 yvdT K Transcriptional regulator
HKALJCNE_00108 1.5e-50 ykkC P Small Multidrug Resistance protein
HKALJCNE_00109 7.1e-50 sugE P Small Multidrug Resistance protein
HKALJCNE_00110 8.3e-93 yvdQ S Protein of unknown function (DUF3231)
HKALJCNE_00112 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKALJCNE_00113 4.5e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HKALJCNE_00114 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HKALJCNE_00115 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HKALJCNE_00116 3.8e-154 malA S Protein of unknown function (DUF1189)
HKALJCNE_00117 6.6e-148 malD P transport
HKALJCNE_00118 1.2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
HKALJCNE_00119 4.8e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HKALJCNE_00120 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HKALJCNE_00121 1.1e-172 yvdE K Transcriptional regulator
HKALJCNE_00122 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HKALJCNE_00123 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HKALJCNE_00124 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HKALJCNE_00125 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HKALJCNE_00126 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKALJCNE_00127 0.0 yxdM V ABC transporter (permease)
HKALJCNE_00128 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HKALJCNE_00129 2.3e-190 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HKALJCNE_00130 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_00131 9.7e-32
HKALJCNE_00132 7.8e-140 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HKALJCNE_00133 1.6e-36 crh G Phosphocarrier protein Chr
HKALJCNE_00134 1.4e-170 whiA K May be required for sporulation
HKALJCNE_00135 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKALJCNE_00136 1.7e-165 rapZ S Displays ATPase and GTPase activities
HKALJCNE_00137 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKALJCNE_00138 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKALJCNE_00139 2.8e-98 usp CBM50 M protein conserved in bacteria
HKALJCNE_00140 6.5e-276 S COG0457 FOG TPR repeat
HKALJCNE_00141 0.0 msbA2 3.6.3.44 V ABC transporter
HKALJCNE_00143 0.0
HKALJCNE_00144 9.9e-76
HKALJCNE_00145 4.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HKALJCNE_00146 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKALJCNE_00147 1e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKALJCNE_00148 9.9e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKALJCNE_00149 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HKALJCNE_00150 2.8e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKALJCNE_00151 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKALJCNE_00152 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKALJCNE_00153 1e-139 yvpB NU protein conserved in bacteria
HKALJCNE_00154 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HKALJCNE_00155 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HKALJCNE_00156 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HKALJCNE_00157 3.4e-161 yvoD P COG0370 Fe2 transport system protein B
HKALJCNE_00158 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKALJCNE_00159 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKALJCNE_00160 3e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKALJCNE_00161 1.2e-126 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKALJCNE_00162 8.9e-133 yvoA K transcriptional
HKALJCNE_00163 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HKALJCNE_00164 3.6e-71 adcR K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_00165 1.2e-227 cypX 1.14.15.13 C Cytochrome P450
HKALJCNE_00166 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HKALJCNE_00167 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_00168 2.7e-203 yvmA EGP Major facilitator Superfamily
HKALJCNE_00169 1.2e-50 yvlD S Membrane
HKALJCNE_00170 2.6e-26 pspB KT PspC domain
HKALJCNE_00171 2.4e-166 yvlB S Putative adhesin
HKALJCNE_00172 1.8e-48 yvlA
HKALJCNE_00173 5.7e-33 yvkN
HKALJCNE_00174 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HKALJCNE_00175 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKALJCNE_00176 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKALJCNE_00177 1.2e-30 csbA S protein conserved in bacteria
HKALJCNE_00178 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HKALJCNE_00179 3.8e-99 yvkB K Transcriptional regulator
HKALJCNE_00180 2.8e-225 yvkA EGP Major facilitator Superfamily
HKALJCNE_00181 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKALJCNE_00182 5.3e-56 swrA S Swarming motility protein
HKALJCNE_00183 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HKALJCNE_00184 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKALJCNE_00185 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HKALJCNE_00186 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
HKALJCNE_00187 3.5e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HKALJCNE_00188 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKALJCNE_00189 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKALJCNE_00190 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKALJCNE_00191 1.8e-65
HKALJCNE_00192 1.9e-08 fliT S bacterial-type flagellum organization
HKALJCNE_00193 2.9e-69 fliS N flagellar protein FliS
HKALJCNE_00194 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HKALJCNE_00195 1.2e-55 flaG N flagellar protein FlaG
HKALJCNE_00196 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HKALJCNE_00197 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HKALJCNE_00198 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HKALJCNE_00199 1.3e-49 yviE
HKALJCNE_00200 1.3e-154 flgL N Belongs to the bacterial flagellin family
HKALJCNE_00201 2.7e-264 flgK N flagellar hook-associated protein
HKALJCNE_00202 4.1e-78 flgN NOU FlgN protein
HKALJCNE_00203 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
HKALJCNE_00204 7e-74 yvyF S flagellar protein
HKALJCNE_00205 1.2e-126 comFC S Phosphoribosyl transferase domain
HKALJCNE_00206 1.1e-44 comFB S Late competence development protein ComFB
HKALJCNE_00207 6.4e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKALJCNE_00208 7.3e-155 degV S protein conserved in bacteria
HKALJCNE_00209 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKALJCNE_00210 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HKALJCNE_00211 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HKALJCNE_00212 6e-163 yvhJ K Transcriptional regulator
HKALJCNE_00213 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HKALJCNE_00214 7.3e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HKALJCNE_00215 4.7e-145 tuaG GT2 M Glycosyltransferase like family 2
HKALJCNE_00216 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
HKALJCNE_00217 3.7e-263 tuaE M Teichuronic acid biosynthesis protein
HKALJCNE_00218 8.9e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKALJCNE_00219 4e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HKALJCNE_00220 4.8e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKALJCNE_00221 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKALJCNE_00222 1.1e-94 M Glycosyltransferase like family 2
HKALJCNE_00223 2.5e-206 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKALJCNE_00224 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HKALJCNE_00225 3.8e-11
HKALJCNE_00226 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HKALJCNE_00227 1.5e-214 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKALJCNE_00228 4.6e-88 M Glycosyltransferase like family 2
HKALJCNE_00229 8.4e-101 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HKALJCNE_00230 1.8e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HKALJCNE_00231 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKALJCNE_00232 3.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKALJCNE_00233 1.7e-132 tagG GM Transport permease protein
HKALJCNE_00234 1.3e-145 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKALJCNE_00235 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HKALJCNE_00236 3.4e-94 M1-753 M FR47-like protein
HKALJCNE_00237 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
HKALJCNE_00238 1.3e-72 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HKALJCNE_00239 3.9e-84 yuaE S DinB superfamily
HKALJCNE_00240 4.3e-106 yuaD
HKALJCNE_00241 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HKALJCNE_00242 1e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HKALJCNE_00243 3.6e-94 yuaC K Belongs to the GbsR family
HKALJCNE_00244 2.2e-91 yuaB
HKALJCNE_00245 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HKALJCNE_00246 2.5e-234 ktrB P Potassium
HKALJCNE_00247 1e-38 yiaA S yiaA/B two helix domain
HKALJCNE_00248 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKALJCNE_00249 1.3e-274 yubD P Major Facilitator Superfamily
HKALJCNE_00250 4.9e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HKALJCNE_00252 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKALJCNE_00253 1.8e-196 yubA S transporter activity
HKALJCNE_00254 5.7e-183 ygjR S Oxidoreductase
HKALJCNE_00255 4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HKALJCNE_00256 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HKALJCNE_00257 2.5e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HKALJCNE_00258 2.3e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HKALJCNE_00259 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HKALJCNE_00260 5.1e-239 mcpA NT chemotaxis protein
HKALJCNE_00261 2.1e-293 mcpA NT chemotaxis protein
HKALJCNE_00262 1.5e-222 mcpA NT chemotaxis protein
HKALJCNE_00263 7.1e-225 mcpA NT chemotaxis protein
HKALJCNE_00264 8.4e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HKALJCNE_00265 1e-35
HKALJCNE_00266 6.3e-72 yugU S Uncharacterised protein family UPF0047
HKALJCNE_00267 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HKALJCNE_00268 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HKALJCNE_00269 1.4e-116 yugP S Zn-dependent protease
HKALJCNE_00270 4.3e-37
HKALJCNE_00271 5.4e-53 mstX S Membrane-integrating protein Mistic
HKALJCNE_00272 2.2e-182 yugO P COG1226 Kef-type K transport systems
HKALJCNE_00273 1.3e-72 yugN S YugN-like family
HKALJCNE_00275 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HKALJCNE_00276 1.1e-228 yugK C Dehydrogenase
HKALJCNE_00277 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HKALJCNE_00278 1.1e-34 yuzA S Domain of unknown function (DUF378)
HKALJCNE_00279 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HKALJCNE_00280 4.3e-200 yugH 2.6.1.1 E Aminotransferase
HKALJCNE_00281 1.6e-85 alaR K Transcriptional regulator
HKALJCNE_00282 4.9e-156 yugF I Hydrolase
HKALJCNE_00283 4.6e-39 yugE S Domain of unknown function (DUF1871)
HKALJCNE_00284 1.7e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HKALJCNE_00285 1.3e-232 T PhoQ Sensor
HKALJCNE_00286 7.4e-70 kapB G Kinase associated protein B
HKALJCNE_00287 4.2e-115 kapD L the KinA pathway to sporulation
HKALJCNE_00289 4.2e-184 yuxJ EGP Major facilitator Superfamily
HKALJCNE_00290 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HKALJCNE_00291 1.8e-74 yuxK S protein conserved in bacteria
HKALJCNE_00292 6.3e-78 yufK S Family of unknown function (DUF5366)
HKALJCNE_00293 1.1e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKALJCNE_00294 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HKALJCNE_00295 6e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HKALJCNE_00296 2.1e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HKALJCNE_00297 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HKALJCNE_00298 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HKALJCNE_00299 1.8e-232 maeN C COG3493 Na citrate symporter
HKALJCNE_00300 5e-15
HKALJCNE_00301 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HKALJCNE_00302 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKALJCNE_00303 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKALJCNE_00304 7.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKALJCNE_00305 3.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKALJCNE_00306 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKALJCNE_00307 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HKALJCNE_00308 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HKALJCNE_00309 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKALJCNE_00310 3e-215 comP 2.7.13.3 T Histidine kinase
HKALJCNE_00311 5.5e-185 comP 2.7.13.3 T Histidine kinase
HKALJCNE_00313 3.1e-149 comQ H Polyprenyl synthetase
HKALJCNE_00315 2.9e-23 yuzC
HKALJCNE_00316 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HKALJCNE_00317 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKALJCNE_00318 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HKALJCNE_00319 1.8e-66 yueI S Protein of unknown function (DUF1694)
HKALJCNE_00320 7.4e-39 yueH S YueH-like protein
HKALJCNE_00321 6.6e-31 yueG S Spore germination protein gerPA/gerPF
HKALJCNE_00322 3.2e-190 yueF S transporter activity
HKALJCNE_00323 8.8e-71 S Protein of unknown function (DUF2283)
HKALJCNE_00324 3.8e-24 S Protein of unknown function (DUF2642)
HKALJCNE_00325 1.4e-95 yueE S phosphohydrolase
HKALJCNE_00326 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_00327 3.2e-59 yueC S Family of unknown function (DUF5383)
HKALJCNE_00328 0.0 esaA S type VII secretion protein EsaA
HKALJCNE_00329 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HKALJCNE_00330 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HKALJCNE_00331 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HKALJCNE_00332 2.8e-45 esxA S Belongs to the WXG100 family
HKALJCNE_00333 5.2e-226 yukF QT Transcriptional regulator
HKALJCNE_00334 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HKALJCNE_00335 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HKALJCNE_00336 5e-36 mbtH S MbtH-like protein
HKALJCNE_00337 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_00338 5.2e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HKALJCNE_00339 1.6e-310 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HKALJCNE_00340 1.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
HKALJCNE_00341 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_00342 2.5e-166 besA S Putative esterase
HKALJCNE_00343 6.4e-121 yuiH S Oxidoreductase molybdopterin binding domain
HKALJCNE_00344 2.6e-93 bioY S Biotin biosynthesis protein
HKALJCNE_00345 1.1e-210 yuiF S antiporter
HKALJCNE_00346 1.7e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HKALJCNE_00347 1.2e-77 yuiD S protein conserved in bacteria
HKALJCNE_00348 4.7e-117 yuiC S protein conserved in bacteria
HKALJCNE_00349 8.4e-27 yuiB S Putative membrane protein
HKALJCNE_00350 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HKALJCNE_00351 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HKALJCNE_00353 5.7e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKALJCNE_00354 4.6e-114 paiB K Putative FMN-binding domain
HKALJCNE_00355 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKALJCNE_00356 3.7e-63 erpA S Belongs to the HesB IscA family
HKALJCNE_00357 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKALJCNE_00358 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKALJCNE_00359 3.2e-39 yuzB S Belongs to the UPF0349 family
HKALJCNE_00360 1e-198 yutJ 1.6.99.3 C NADH dehydrogenase
HKALJCNE_00361 1.1e-55 yuzD S protein conserved in bacteria
HKALJCNE_00362 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HKALJCNE_00363 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HKALJCNE_00364 3.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKALJCNE_00365 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HKALJCNE_00366 1.8e-240 hom 1.1.1.3 E homoserine dehydrogenase
HKALJCNE_00367 6.5e-198 yutH S Spore coat protein
HKALJCNE_00368 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HKALJCNE_00369 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKALJCNE_00370 3e-75 yutE S Protein of unknown function DUF86
HKALJCNE_00371 9.7e-48 yutD S protein conserved in bacteria
HKALJCNE_00372 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKALJCNE_00373 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HKALJCNE_00374 4.5e-196 lytH M Peptidase, M23
HKALJCNE_00375 3.9e-131 yunB S Sporulation protein YunB (Spo_YunB)
HKALJCNE_00376 1.1e-47 yunC S Domain of unknown function (DUF1805)
HKALJCNE_00377 4.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKALJCNE_00378 5.9e-141 yunE S membrane transporter protein
HKALJCNE_00379 4.3e-171 yunF S Protein of unknown function DUF72
HKALJCNE_00380 1.7e-57 yunG
HKALJCNE_00381 2.1e-252 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HKALJCNE_00382 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
HKALJCNE_00383 5.3e-232 pbuX F Permease family
HKALJCNE_00384 1.4e-221 pbuX F xanthine
HKALJCNE_00385 1.9e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HKALJCNE_00386 7.8e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HKALJCNE_00388 6.9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HKALJCNE_00389 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HKALJCNE_00390 8.3e-143 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HKALJCNE_00391 8.4e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HKALJCNE_00392 1e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HKALJCNE_00393 5.6e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HKALJCNE_00394 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HKALJCNE_00395 1.2e-168 bsn L Ribonuclease
HKALJCNE_00396 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_00397 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_00400 4.5e-125 2.7.1.74, 2.7.1.76 F nucleoside 2-deoxyribosyltransferase
HKALJCNE_00401 1.8e-46 S SMI1-KNR4 cell-wall
HKALJCNE_00402 1.6e-43
HKALJCNE_00403 2.3e-147 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKALJCNE_00404 3.5e-13
HKALJCNE_00405 8.3e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HKALJCNE_00406 8.7e-30 cspL K Cold shock
HKALJCNE_00407 2.3e-78 carD K Transcription factor
HKALJCNE_00408 1.1e-161 rhaS5 K AraC-like ligand binding domain
HKALJCNE_00409 4.9e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKALJCNE_00410 8.1e-165 ydeE K AraC family transcriptional regulator
HKALJCNE_00411 9e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKALJCNE_00412 1.1e-218 ydeG EGP Major facilitator superfamily
HKALJCNE_00413 1.4e-44 ydeH
HKALJCNE_00414 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HKALJCNE_00415 4e-116
HKALJCNE_00416 1e-151 ydeK EG -transporter
HKALJCNE_00417 4.3e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKALJCNE_00418 2.7e-73 maoC I N-terminal half of MaoC dehydratase
HKALJCNE_00419 1.2e-103 ydeN S Serine hydrolase
HKALJCNE_00420 5.7e-55 K HxlR-like helix-turn-helix
HKALJCNE_00421 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HKALJCNE_00422 2.8e-57 arsR K transcriptional
HKALJCNE_00423 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKALJCNE_00424 3.5e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HKALJCNE_00425 1.7e-142 ydfB J GNAT acetyltransferase
HKALJCNE_00426 2.8e-149 lytR K Transcriptional regulator
HKALJCNE_00427 1.2e-122 nodB1 G deacetylase
HKALJCNE_00428 2.5e-158
HKALJCNE_00429 1.7e-212 T GHKL domain
HKALJCNE_00430 1.3e-121 T Transcriptional regulatory protein, C terminal
HKALJCNE_00431 6.2e-144 ydfC EG EamA-like transporter family
HKALJCNE_00432 2.5e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKALJCNE_00433 1.4e-115 ydfE S Flavin reductase like domain
HKALJCNE_00434 1.3e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HKALJCNE_00435 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HKALJCNE_00437 3e-175 ydfH 2.7.13.3 T Histidine kinase
HKALJCNE_00438 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKALJCNE_00439 0.0 ydfJ S drug exporters of the RND superfamily
HKALJCNE_00440 1.3e-173 S Alpha/beta hydrolase family
HKALJCNE_00441 2.1e-115 S Protein of unknown function (DUF554)
HKALJCNE_00442 1.6e-146 K Bacterial transcription activator, effector binding domain
HKALJCNE_00443 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKALJCNE_00444 2.1e-111 ydfN C nitroreductase
HKALJCNE_00445 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HKALJCNE_00446 1.2e-62 mhqP S DoxX
HKALJCNE_00447 1.2e-55 traF CO Thioredoxin
HKALJCNE_00448 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HKALJCNE_00449 1.1e-30
HKALJCNE_00451 1.4e-88 ydfR S Protein of unknown function (DUF421)
HKALJCNE_00452 2.6e-121 ydfS S Protein of unknown function (DUF421)
HKALJCNE_00453 1.7e-67 cotP O Belongs to the small heat shock protein (HSP20) family
HKALJCNE_00454 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
HKALJCNE_00455 2.5e-32 ydgB S Spore germination protein gerPA/gerPF
HKALJCNE_00456 4.5e-98 K Bacterial regulatory proteins, tetR family
HKALJCNE_00457 2.1e-52 S DoxX-like family
HKALJCNE_00458 1.6e-82 yycN 2.3.1.128 K Acetyltransferase
HKALJCNE_00459 2.9e-304 expZ S ABC transporter
HKALJCNE_00460 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HKALJCNE_00461 2.5e-89 dinB S DinB family
HKALJCNE_00462 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_00463 0.0 ydgH S drug exporters of the RND superfamily
HKALJCNE_00464 1e-113 drgA C nitroreductase
HKALJCNE_00465 2.1e-68 ydgJ K Winged helix DNA-binding domain
HKALJCNE_00466 6.3e-208 tcaB EGP Major facilitator Superfamily
HKALJCNE_00467 7.9e-121 ydhB S membrane transporter protein
HKALJCNE_00468 3.2e-121 ydhC K FCD
HKALJCNE_00469 9e-242 ydhD M Glycosyl hydrolase
HKALJCNE_00470 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKALJCNE_00471 6.7e-125
HKALJCNE_00472 1.7e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HKALJCNE_00473 1.6e-66 frataxin S Domain of unknown function (DU1801)
HKALJCNE_00475 1.8e-81 K Acetyltransferase (GNAT) domain
HKALJCNE_00476 3.7e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKALJCNE_00477 6.1e-97 ydhK M Protein of unknown function (DUF1541)
HKALJCNE_00478 1e-199 pbuE EGP Major facilitator Superfamily
HKALJCNE_00479 7.9e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKALJCNE_00480 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKALJCNE_00481 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKALJCNE_00482 1.8e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKALJCNE_00483 3.7e-131 ydhQ K UTRA
HKALJCNE_00484 3.3e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HKALJCNE_00485 7.6e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKALJCNE_00486 2.2e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HKALJCNE_00487 2.3e-156 ydhU P Catalase
HKALJCNE_00489 3.4e-31 csfB S Inhibitor of sigma-G Gin
HKALJCNE_00490 5.7e-75 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HKALJCNE_00491 3.2e-201 yaaN P Belongs to the TelA family
HKALJCNE_00492 1.1e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HKALJCNE_00493 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKALJCNE_00494 2.2e-54 yaaQ S protein conserved in bacteria
HKALJCNE_00495 3.4e-71 yaaR S protein conserved in bacteria
HKALJCNE_00496 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HKALJCNE_00497 6.1e-146 yaaT S stage 0 sporulation protein
HKALJCNE_00498 4.8e-31 yabA L Involved in initiation control of chromosome replication
HKALJCNE_00499 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
HKALJCNE_00500 1.5e-49 yazA L endonuclease containing a URI domain
HKALJCNE_00501 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKALJCNE_00502 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HKALJCNE_00503 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKALJCNE_00504 1.2e-143 tatD L hydrolase, TatD
HKALJCNE_00505 2.6e-167 rpfB GH23 T protein conserved in bacteria
HKALJCNE_00506 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKALJCNE_00507 4.5e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKALJCNE_00508 1.6e-136 yabG S peptidase
HKALJCNE_00509 7.8e-39 veg S protein conserved in bacteria
HKALJCNE_00510 8.3e-27 sspF S DNA topological change
HKALJCNE_00511 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKALJCNE_00512 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HKALJCNE_00513 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HKALJCNE_00514 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HKALJCNE_00515 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKALJCNE_00516 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKALJCNE_00517 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKALJCNE_00518 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKALJCNE_00519 2.4e-39 yabK S Peptide ABC transporter permease
HKALJCNE_00520 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKALJCNE_00521 1.5e-92 spoVT K stage V sporulation protein
HKALJCNE_00522 1.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKALJCNE_00523 8.6e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HKALJCNE_00524 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HKALJCNE_00525 1.5e-49 yabP S Sporulation protein YabP
HKALJCNE_00526 9.5e-107 yabQ S spore cortex biosynthesis protein
HKALJCNE_00527 1.1e-44 divIC D Septum formation initiator
HKALJCNE_00528 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HKALJCNE_00530 1.3e-63 hxlR K transcriptional
HKALJCNE_00531 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HKALJCNE_00532 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HKALJCNE_00533 1e-179 tlpC 2.7.13.3 NT chemotaxis protein
HKALJCNE_00534 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
HKALJCNE_00535 1.7e-69 nin S Competence protein J (ComJ)
HKALJCNE_00536 3.3e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKALJCNE_00537 2.7e-121 S AAA domain
HKALJCNE_00538 9.3e-24
HKALJCNE_00539 4.1e-45 K MarR family
HKALJCNE_00540 3.9e-51 yckD S Protein of unknown function (DUF2680)
HKALJCNE_00541 5.3e-75 yckC S membrane
HKALJCNE_00543 3.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HKALJCNE_00544 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HKALJCNE_00545 7e-228 yciC S GTPases (G3E family)
HKALJCNE_00546 3e-107 yciB M ErfK YbiS YcfS YnhG
HKALJCNE_00547 4.6e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HKALJCNE_00548 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
HKALJCNE_00549 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HKALJCNE_00550 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKALJCNE_00551 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HKALJCNE_00552 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HKALJCNE_00553 6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HKALJCNE_00554 3e-187 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HKALJCNE_00555 2.5e-158 I alpha/beta hydrolase fold
HKALJCNE_00556 2e-139 ycgR S permeases
HKALJCNE_00557 2.2e-143 ycgQ S membrane
HKALJCNE_00558 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HKALJCNE_00559 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKALJCNE_00560 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKALJCNE_00561 5.1e-170 ycgM E Proline dehydrogenase
HKALJCNE_00562 1.9e-144 ycgL S Predicted nucleotidyltransferase
HKALJCNE_00563 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HKALJCNE_00564 1.3e-176 oxyR3 K LysR substrate binding domain
HKALJCNE_00565 1.4e-144 yafE Q ubiE/COQ5 methyltransferase family
HKALJCNE_00566 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKALJCNE_00568 2.1e-108 tmrB S AAA domain
HKALJCNE_00569 2.6e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKALJCNE_00570 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HKALJCNE_00571 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HKALJCNE_00572 1.5e-151 yqcI S YqcI/YcgG family
HKALJCNE_00573 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HKALJCNE_00574 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_00575 3.9e-263 mdr EGP Major facilitator Superfamily
HKALJCNE_00576 3e-290 lctP C L-lactate permease
HKALJCNE_00577 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKALJCNE_00578 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HKALJCNE_00579 7e-81 ycgB
HKALJCNE_00580 3.6e-255 ycgA S Membrane
HKALJCNE_00581 9.2e-217 amhX S amidohydrolase
HKALJCNE_00582 5.3e-164 opuAC E glycine betaine
HKALJCNE_00583 1.3e-127 opuAB P glycine betaine
HKALJCNE_00584 5.1e-229 proV 3.6.3.32 E glycine betaine
HKALJCNE_00585 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKALJCNE_00586 5.9e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
HKALJCNE_00587 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
HKALJCNE_00588 2e-192 yceH P Belongs to the TelA family
HKALJCNE_00589 0.0 yceG S Putative component of 'biosynthetic module'
HKALJCNE_00590 6.3e-137 terC P Protein of unknown function (DUF475)
HKALJCNE_00591 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HKALJCNE_00592 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HKALJCNE_00593 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HKALJCNE_00594 9.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKALJCNE_00595 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HKALJCNE_00596 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HKALJCNE_00597 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HKALJCNE_00598 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HKALJCNE_00599 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HKALJCNE_00600 6.1e-173 S response regulator aspartate phosphatase
HKALJCNE_00601 1.3e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
HKALJCNE_00602 2.4e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_00603 7.7e-274 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_00604 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HKALJCNE_00605 1e-173 yccK C Aldo keto reductase
HKALJCNE_00606 2.2e-202 natB CP ABC-2 family transporter protein
HKALJCNE_00607 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HKALJCNE_00608 9.9e-112 lytR_2 T LytTr DNA-binding domain
HKALJCNE_00609 5.2e-157 2.7.13.3 T GHKL domain
HKALJCNE_00610 2.3e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
HKALJCNE_00611 7.1e-57 S RDD family
HKALJCNE_00612 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HKALJCNE_00613 1.2e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HKALJCNE_00614 1.3e-99 yxaF K Transcriptional regulator
HKALJCNE_00615 3e-225 lmrB EGP the major facilitator superfamily
HKALJCNE_00616 7.8e-205 ycbU E Selenocysteine lyase
HKALJCNE_00617 6.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKALJCNE_00618 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKALJCNE_00619 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKALJCNE_00620 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HKALJCNE_00621 3.6e-134 ycbR T vWA found in TerF C terminus
HKALJCNE_00622 1.3e-78 sleB 3.5.1.28 M Cell wall
HKALJCNE_00623 4.1e-52 ycbP S Protein of unknown function (DUF2512)
HKALJCNE_00624 2.1e-112 S ABC-2 family transporter protein
HKALJCNE_00625 5.9e-166 ycbN V ABC transporter, ATP-binding protein
HKALJCNE_00626 1.5e-169 T PhoQ Sensor
HKALJCNE_00627 3.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_00628 1.8e-114 eamA1 EG spore germination
HKALJCNE_00629 1.7e-23 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HKALJCNE_00630 2e-174 ycbJ S Macrolide 2'-phosphotransferase
HKALJCNE_00631 3.5e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
HKALJCNE_00632 1.5e-124 ycbG K FCD
HKALJCNE_00633 8.8e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKALJCNE_00634 2.7e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HKALJCNE_00635 2.2e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKALJCNE_00636 7.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HKALJCNE_00637 5.8e-169 glnL T Regulator
HKALJCNE_00638 3.6e-228 phoQ 2.7.13.3 T Histidine kinase
HKALJCNE_00639 9.4e-186 glsA 3.5.1.2 E Belongs to the glutaminase family
HKALJCNE_00640 2.8e-255 agcS E Sodium alanine symporter
HKALJCNE_00641 1.1e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HKALJCNE_00642 4.4e-261 mmuP E amino acid
HKALJCNE_00643 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKALJCNE_00644 1.4e-127 K UTRA
HKALJCNE_00645 9.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKALJCNE_00646 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKALJCNE_00647 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKALJCNE_00648 3.9e-192 yceA S Belongs to the UPF0176 family
HKALJCNE_00649 9.6e-250 S Erythromycin esterase
HKALJCNE_00650 4.6e-45 ybfN
HKALJCNE_00651 6.9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HKALJCNE_00652 2.7e-85 ybfM S SNARE associated Golgi protein
HKALJCNE_00653 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKALJCNE_00654 2.2e-165 S Alpha/beta hydrolase family
HKALJCNE_00656 5.8e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HKALJCNE_00657 1.5e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKALJCNE_00658 1.8e-77 M nucleic acid phosphodiester bond hydrolysis
HKALJCNE_00659 8e-148 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HKALJCNE_00660 2.3e-145 msmR K AraC-like ligand binding domain
HKALJCNE_00661 1.7e-160 ybfH EG EamA-like transporter family
HKALJCNE_00662 0.0 ybfG M Domain of unknown function (DUF1906)
HKALJCNE_00664 1.8e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
HKALJCNE_00665 4.4e-169 ybfA 3.4.15.5 K FR47-like protein
HKALJCNE_00666 1.5e-34 S Protein of unknown function (DUF2651)
HKALJCNE_00667 7.3e-258 glpT G -transporter
HKALJCNE_00668 1.5e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKALJCNE_00669 1.8e-290 ybeC E amino acid
HKALJCNE_00670 4.9e-41 ybyB
HKALJCNE_00671 2.5e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HKALJCNE_00672 2.6e-149 ybxI 3.5.2.6 V beta-lactamase
HKALJCNE_00673 4.9e-30 ybxH S Family of unknown function (DUF5370)
HKALJCNE_00674 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HKALJCNE_00675 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HKALJCNE_00676 1.2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HKALJCNE_00677 8.8e-37 S TM2 domain
HKALJCNE_00678 1.3e-10
HKALJCNE_00679 1.1e-116
HKALJCNE_00680 2.1e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HKALJCNE_00681 5e-17
HKALJCNE_00683 4e-100 S aspartate phosphatase
HKALJCNE_00685 6.9e-19
HKALJCNE_00686 3.3e-28 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKALJCNE_00687 1.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKALJCNE_00688 1.2e-100 yokH G SMI1 / KNR4 family
HKALJCNE_00689 2.2e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HKALJCNE_00690 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HKALJCNE_00691 2.3e-133 yobQ K helix_turn_helix, arabinose operon control protein
HKALJCNE_00692 4.6e-137 yobR 2.3.1.1 J FR47-like protein
HKALJCNE_00693 3.3e-98 yobS K Transcriptional regulator
HKALJCNE_00694 3.6e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HKALJCNE_00695 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
HKALJCNE_00696 2.1e-171 yobV K WYL domain
HKALJCNE_00697 1e-93 yobW
HKALJCNE_00698 1e-51 czrA K transcriptional
HKALJCNE_00699 5.8e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKALJCNE_00700 1.5e-92 yozB S membrane
HKALJCNE_00701 6.4e-145
HKALJCNE_00702 2.5e-94 yocC
HKALJCNE_00703 9.3e-186 yocD 3.4.17.13 V peptidase S66
HKALJCNE_00704 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HKALJCNE_00705 4.6e-197 desK 2.7.13.3 T Histidine kinase
HKALJCNE_00706 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKALJCNE_00708 1.7e-111 yocH CBM50 M COG1388 FOG LysM repeat
HKALJCNE_00709 0.0 recQ 3.6.4.12 L DNA helicase
HKALJCNE_00710 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKALJCNE_00711 7.4e-83 dksA T general stress protein
HKALJCNE_00712 8.4e-54 yocL
HKALJCNE_00713 2e-30
HKALJCNE_00714 6.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HKALJCNE_00715 1.1e-40 yozN
HKALJCNE_00716 1.9e-36 yocN
HKALJCNE_00717 4.2e-56 yozO S Bacterial PH domain
HKALJCNE_00718 2.7e-31 yozC
HKALJCNE_00719 2e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HKALJCNE_00720 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HKALJCNE_00721 6e-165 sodA 1.15.1.1 P Superoxide dismutase
HKALJCNE_00722 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKALJCNE_00723 1.1e-167 yocS S -transporter
HKALJCNE_00724 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HKALJCNE_00725 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HKALJCNE_00726 0.0 yojO P Von Willebrand factor
HKALJCNE_00727 1.9e-161 yojN S ATPase family associated with various cellular activities (AAA)
HKALJCNE_00728 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKALJCNE_00729 2.1e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKALJCNE_00730 2.6e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HKALJCNE_00731 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKALJCNE_00733 1.6e-244 norM V Multidrug efflux pump
HKALJCNE_00734 7.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKALJCNE_00735 2.1e-125 yojG S deacetylase
HKALJCNE_00736 2.2e-60 yojF S Protein of unknown function (DUF1806)
HKALJCNE_00737 3.3e-43
HKALJCNE_00738 5.6e-161 rarD S -transporter
HKALJCNE_00739 1.2e-58 yozR S COG0071 Molecular chaperone (small heat shock protein)
HKALJCNE_00740 3.4e-09
HKALJCNE_00741 1.2e-204 gntP EG COG2610 H gluconate symporter and related permeases
HKALJCNE_00742 4.7e-64 yodA S tautomerase
HKALJCNE_00743 4.4e-55 yodB K transcriptional
HKALJCNE_00744 1.4e-107 yodC C nitroreductase
HKALJCNE_00745 6.5e-113 mhqD S Carboxylesterase
HKALJCNE_00746 1.1e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
HKALJCNE_00747 6.2e-28 S Protein of unknown function (DUF3311)
HKALJCNE_00748 8.7e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKALJCNE_00749 1.2e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HKALJCNE_00750 5.4e-127 yodH Q Methyltransferase
HKALJCNE_00751 1.5e-23 yodI
HKALJCNE_00752 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HKALJCNE_00753 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HKALJCNE_00754 5.3e-09
HKALJCNE_00755 3.6e-54 yodL S YodL-like
HKALJCNE_00756 3.5e-106 yodM 3.6.1.27 I Acid phosphatase homologues
HKALJCNE_00757 2.8e-24 yozD S YozD-like protein
HKALJCNE_00759 6e-123 yodN
HKALJCNE_00760 1.4e-36 yozE S Belongs to the UPF0346 family
HKALJCNE_00761 2.9e-47 yokU S YokU-like protein, putative antitoxin
HKALJCNE_00762 3.9e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HKALJCNE_00763 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HKALJCNE_00764 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HKALJCNE_00765 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKALJCNE_00766 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKALJCNE_00767 2.3e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKALJCNE_00769 5e-142 yiiD K acetyltransferase
HKALJCNE_00770 3.6e-254 cgeD M maturation of the outermost layer of the spore
HKALJCNE_00771 4.5e-38 cgeC
HKALJCNE_00772 3.1e-63 cgeA
HKALJCNE_00773 7e-178 cgeB S Spore maturation protein
HKALJCNE_00774 3.2e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HKALJCNE_00775 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HKALJCNE_00776 3.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HKALJCNE_00777 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKALJCNE_00778 1.6e-70 ypoP K transcriptional
HKALJCNE_00779 2.9e-222 mepA V MATE efflux family protein
HKALJCNE_00780 5.5e-29 ypmT S Uncharacterized ympT
HKALJCNE_00781 7.2e-98 ypmS S protein conserved in bacteria
HKALJCNE_00782 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HKALJCNE_00783 7.4e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HKALJCNE_00784 3.4e-39 ypmP S Protein of unknown function (DUF2535)
HKALJCNE_00785 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKALJCNE_00786 2.5e-189 msmR K Transcriptional regulator
HKALJCNE_00787 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
HKALJCNE_00788 3.8e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HKALJCNE_00789 2.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HKALJCNE_00790 2.8e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKALJCNE_00791 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HKALJCNE_00792 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HKALJCNE_00793 3.1e-220 bioI 1.14.14.46 C Cytochrome P450
HKALJCNE_00794 8.1e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HKALJCNE_00795 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HKALJCNE_00796 2e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HKALJCNE_00797 0.0 ytdP K Transcriptional regulator
HKALJCNE_00798 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HKALJCNE_00799 1.6e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HKALJCNE_00800 3.6e-70 yteS G transport
HKALJCNE_00801 3.2e-247 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HKALJCNE_00802 6.5e-114 yteU S Integral membrane protein
HKALJCNE_00803 3.1e-26 yteV S Sporulation protein Cse60
HKALJCNE_00804 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HKALJCNE_00805 8.2e-232 ytfP S HI0933-like protein
HKALJCNE_00806 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKALJCNE_00807 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKALJCNE_00808 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HKALJCNE_00809 1.6e-131 ythP V ABC transporter
HKALJCNE_00810 2.4e-201 ythQ U Bacterial ABC transporter protein EcsB
HKALJCNE_00811 2.1e-225 pbuO S permease
HKALJCNE_00812 2.7e-271 pepV 3.5.1.18 E Dipeptidase
HKALJCNE_00813 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKALJCNE_00814 2.9e-99 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HKALJCNE_00815 1.3e-165 ytlQ
HKALJCNE_00816 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HKALJCNE_00817 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HKALJCNE_00818 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HKALJCNE_00819 2e-45 ytzH S YtzH-like protein
HKALJCNE_00820 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKALJCNE_00821 1.6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HKALJCNE_00822 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HKALJCNE_00823 2.2e-51 ytzB S small secreted protein
HKALJCNE_00824 2.6e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HKALJCNE_00825 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HKALJCNE_00826 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKALJCNE_00827 2.4e-147 ytpQ S Belongs to the UPF0354 family
HKALJCNE_00828 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKALJCNE_00829 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HKALJCNE_00830 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKALJCNE_00831 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKALJCNE_00832 6.2e-17 ytxH S COG4980 Gas vesicle protein
HKALJCNE_00833 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
HKALJCNE_00834 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HKALJCNE_00835 1.7e-182 ccpA K catabolite control protein A
HKALJCNE_00836 2.1e-146 motA N flagellar motor
HKALJCNE_00837 1.4e-125 motS N Flagellar motor protein
HKALJCNE_00838 6.1e-224 acuC BQ histone deacetylase
HKALJCNE_00839 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HKALJCNE_00840 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HKALJCNE_00841 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKALJCNE_00842 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKALJCNE_00844 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKALJCNE_00845 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HKALJCNE_00846 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HKALJCNE_00847 1e-108 yttP K Transcriptional regulator
HKALJCNE_00848 5e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HKALJCNE_00849 2.7e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKALJCNE_00850 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HKALJCNE_00851 5e-207 iscS2 2.8.1.7 E Cysteine desulfurase
HKALJCNE_00852 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKALJCNE_00853 2e-29 sspB S spore protein
HKALJCNE_00854 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKALJCNE_00855 0.0 ytcJ S amidohydrolase
HKALJCNE_00856 8.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKALJCNE_00857 3.5e-180 sppA OU signal peptide peptidase SppA
HKALJCNE_00858 2.5e-86 yteJ S RDD family
HKALJCNE_00859 8.1e-115 ytfI S Protein of unknown function (DUF2953)
HKALJCNE_00860 8.7e-70 ytfJ S Sporulation protein YtfJ
HKALJCNE_00861 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKALJCNE_00862 5e-163 ytxK 2.1.1.72 L DNA methylase
HKALJCNE_00863 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKALJCNE_00864 3.4e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HKALJCNE_00865 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKALJCNE_00866 9.9e-266 argH 4.3.2.1 E argininosuccinate lyase
HKALJCNE_00868 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_00869 1.7e-130 ytkL S Belongs to the UPF0173 family
HKALJCNE_00870 8e-241 ytoI K transcriptional regulator containing CBS domains
HKALJCNE_00871 2.4e-47 ytpI S YtpI-like protein
HKALJCNE_00872 3.9e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HKALJCNE_00873 4.6e-28
HKALJCNE_00874 8.2e-69 ytrI
HKALJCNE_00875 3.2e-56 ytrH S Sporulation protein YtrH
HKALJCNE_00876 0.0 dnaE 2.7.7.7 L DNA polymerase
HKALJCNE_00877 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HKALJCNE_00878 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKALJCNE_00879 2.8e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HKALJCNE_00880 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKALJCNE_00881 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKALJCNE_00882 1.6e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HKALJCNE_00883 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HKALJCNE_00884 4.7e-71 yeaL S membrane
HKALJCNE_00885 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HKALJCNE_00886 4.1e-242 icd 1.1.1.42 C isocitrate
HKALJCNE_00887 1.2e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HKALJCNE_00888 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_00889 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HKALJCNE_00890 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKALJCNE_00891 1.6e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKALJCNE_00892 4.3e-107 ytaF P Probably functions as a manganese efflux pump
HKALJCNE_00893 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKALJCNE_00894 8.9e-161 ytbE S reductase
HKALJCNE_00895 2.5e-201 ytbD EGP Major facilitator Superfamily
HKALJCNE_00896 9.9e-67 ytcD K Transcriptional regulator
HKALJCNE_00897 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKALJCNE_00898 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HKALJCNE_00899 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKALJCNE_00900 2.2e-265 dnaB L Membrane attachment protein
HKALJCNE_00901 3.6e-171 dnaI L Primosomal protein DnaI
HKALJCNE_00902 4.6e-109 ytxB S SNARE associated Golgi protein
HKALJCNE_00903 1.4e-158 ytxC S YtxC-like family
HKALJCNE_00905 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKALJCNE_00906 7.3e-149 ysaA S HAD-hyrolase-like
HKALJCNE_00907 3.4e-39 S COG NOG14552 non supervised orthologous group
HKALJCNE_00908 7.3e-19 S Protein conserved in bacteria
HKALJCNE_00910 1.5e-137 S nuclease activity
HKALJCNE_00911 5.5e-53
HKALJCNE_00912 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKALJCNE_00913 1e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKALJCNE_00914 1.1e-72 yxiE T Belongs to the universal stress protein A family
HKALJCNE_00915 3.3e-164 yxxF EG EamA-like transporter family
HKALJCNE_00916 0.0 wapA M COG3209 Rhs family protein
HKALJCNE_00917 7.6e-16 yxiG
HKALJCNE_00918 8.3e-13 yxiG
HKALJCNE_00919 1e-135
HKALJCNE_00920 4.3e-83 yxiI S Protein of unknown function (DUF2716)
HKALJCNE_00921 7.7e-43 yxiJ S YxiJ-like protein
HKALJCNE_00924 4e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HKALJCNE_00925 1.9e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HKALJCNE_00926 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
HKALJCNE_00927 6.6e-114
HKALJCNE_00928 8.3e-151 licT K transcriptional antiterminator
HKALJCNE_00929 1.1e-143 exoK GH16 M licheninase activity
HKALJCNE_00930 6.6e-224 citH C Citrate transporter
HKALJCNE_00931 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HKALJCNE_00932 3e-47 yxiS
HKALJCNE_00933 2.6e-102 T Domain of unknown function (DUF4163)
HKALJCNE_00934 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKALJCNE_00936 7.1e-87 rlmA 2.1.1.187 Q Methyltransferase domain
HKALJCNE_00937 3.2e-44 rlmA 2.1.1.187 Q Methyltransferase domain
HKALJCNE_00938 7.5e-254 yxjC EG COG2610 H gluconate symporter and related permeases
HKALJCNE_00939 1.2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKALJCNE_00940 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKALJCNE_00941 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKALJCNE_00942 1.7e-218 yxjG 2.1.1.14 E Methionine synthase
HKALJCNE_00943 1.1e-219 yxjG 2.1.1.14 E Methionine synthase
HKALJCNE_00944 1.6e-85 yxjI S LURP-one-related
HKALJCNE_00947 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKALJCNE_00948 3.4e-115 K helix_turn_helix, Lux Regulon
HKALJCNE_00949 4.7e-179 yxjM T Signal transduction histidine kinase
HKALJCNE_00950 2e-77 S Protein of unknown function (DUF1453)
HKALJCNE_00951 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKALJCNE_00952 1.1e-73 yxkC S Domain of unknown function (DUF4352)
HKALJCNE_00953 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKALJCNE_00954 1.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKALJCNE_00955 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HKALJCNE_00956 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HKALJCNE_00957 1.6e-154 yxkH G Polysaccharide deacetylase
HKALJCNE_00959 4.7e-311 3.4.24.84 O Peptidase family M48
HKALJCNE_00960 2.1e-228 cimH C COG3493 Na citrate symporter
HKALJCNE_00961 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HKALJCNE_00962 1.9e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HKALJCNE_00963 7.1e-311 cydD V ATP-binding
HKALJCNE_00964 0.0 cydD V ATP-binding protein
HKALJCNE_00965 2.9e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKALJCNE_00966 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HKALJCNE_00967 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_00968 8.1e-46 yxlC S Family of unknown function (DUF5345)
HKALJCNE_00969 1.4e-27
HKALJCNE_00970 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
HKALJCNE_00971 9.7e-166 yxlF V ABC transporter, ATP-binding protein
HKALJCNE_00972 6.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKALJCNE_00973 2.9e-213 yxlH EGP Major facilitator Superfamily
HKALJCNE_00974 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HKALJCNE_00975 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HKALJCNE_00976 1.1e-19 yxzF
HKALJCNE_00977 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HKALJCNE_00978 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HKALJCNE_00979 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKALJCNE_00980 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKALJCNE_00981 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKALJCNE_00982 5.3e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKALJCNE_00983 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_00984 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKALJCNE_00985 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_00986 8e-232 dltB M membrane protein involved in D-alanine export
HKALJCNE_00987 1.9e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_00988 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HKALJCNE_00989 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HKALJCNE_00990 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HKALJCNE_00991 9.8e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKALJCNE_00992 4e-87 ywaE K Transcriptional regulator
HKALJCNE_00993 1.1e-124 ywaF S Integral membrane protein
HKALJCNE_00994 1.6e-168 gspA M General stress
HKALJCNE_00995 1.2e-152 sacY K transcriptional antiterminator
HKALJCNE_00996 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKALJCNE_00997 2.2e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
HKALJCNE_00998 5.4e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKALJCNE_00999 4.1e-124 ywbB S Protein of unknown function (DUF2711)
HKALJCNE_01000 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HKALJCNE_01001 7.6e-67 ywbC 4.4.1.5 E glyoxalase
HKALJCNE_01002 7.7e-219 ywbD 2.1.1.191 J Methyltransferase
HKALJCNE_01003 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HKALJCNE_01004 3e-202 ywbF EGP Major facilitator Superfamily
HKALJCNE_01005 2.3e-111 ywbG M effector of murein hydrolase
HKALJCNE_01006 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HKALJCNE_01007 4.3e-153 ywbI K Transcriptional regulator
HKALJCNE_01008 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKALJCNE_01009 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKALJCNE_01010 2.9e-252 P COG0672 High-affinity Fe2 Pb2 permease
HKALJCNE_01011 9.3e-185 ycdO P periplasmic lipoprotein involved in iron transport
HKALJCNE_01012 9.3e-223 ywbN P Dyp-type peroxidase family protein
HKALJCNE_01013 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKALJCNE_01014 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKALJCNE_01015 9.8e-49 ywcB S Protein of unknown function, DUF485
HKALJCNE_01017 1.1e-121 ywcC K transcriptional regulator
HKALJCNE_01018 9.5e-60 gtcA S GtrA-like protein
HKALJCNE_01019 4.5e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKALJCNE_01020 3.9e-303 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKALJCNE_01021 1e-35 ywzA S membrane
HKALJCNE_01022 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HKALJCNE_01023 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKALJCNE_01024 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HKALJCNE_01025 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HKALJCNE_01026 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HKALJCNE_01027 2.9e-202 rodA D Belongs to the SEDS family
HKALJCNE_01028 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HKALJCNE_01029 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKALJCNE_01030 0.0 vpr O Belongs to the peptidase S8 family
HKALJCNE_01032 1.2e-149 sacT K transcriptional antiterminator
HKALJCNE_01033 1.1e-138 focA P Formate/nitrite transporter
HKALJCNE_01034 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKALJCNE_01035 1.9e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HKALJCNE_01036 2e-28 ywdA
HKALJCNE_01037 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKALJCNE_01038 1.3e-57 pex K Transcriptional regulator PadR-like family
HKALJCNE_01039 1.4e-113 ywdD
HKALJCNE_01041 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HKALJCNE_01042 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKALJCNE_01043 2.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HKALJCNE_01044 5e-48 ywdI S Family of unknown function (DUF5327)
HKALJCNE_01045 3.7e-238 ywdJ F Xanthine uracil
HKALJCNE_01046 4.3e-59 ywdK S small membrane protein
HKALJCNE_01047 2.1e-73 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HKALJCNE_01048 9.1e-144 spsA M Spore Coat
HKALJCNE_01049 4.9e-265 spsB M Capsule polysaccharide biosynthesis protein
HKALJCNE_01050 1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
HKALJCNE_01051 1.7e-162 spsD 2.3.1.210 K Spore Coat
HKALJCNE_01052 7.8e-213 spsE 2.5.1.56 M acid synthase
HKALJCNE_01053 3.1e-130 spsF M Spore Coat
HKALJCNE_01054 2.6e-186 spsG M Spore Coat
HKALJCNE_01055 9.3e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKALJCNE_01056 1.1e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKALJCNE_01057 1.5e-88 ylbP K n-acetyltransferase
HKALJCNE_01058 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HKALJCNE_01059 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKALJCNE_01060 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HKALJCNE_01062 3.3e-228 ylbM S Belongs to the UPF0348 family
HKALJCNE_01063 6.8e-187 ylbL T Belongs to the peptidase S16 family
HKALJCNE_01064 2.2e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
HKALJCNE_01065 3.2e-220 ylbJ S Sporulation integral membrane protein YlbJ
HKALJCNE_01066 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKALJCNE_01067 1.3e-96 rsmD 2.1.1.171 L Methyltransferase
HKALJCNE_01068 3.7e-38 ylbG S UPF0298 protein
HKALJCNE_01069 1.8e-75 ylbF S Belongs to the UPF0342 family
HKALJCNE_01070 6.7e-37 ylbE S YlbE-like protein
HKALJCNE_01071 4.1e-63 ylbD S Putative coat protein
HKALJCNE_01072 9.6e-200 ylbC S protein with SCP PR1 domains
HKALJCNE_01073 2.6e-74 ylbB T COG0517 FOG CBS domain
HKALJCNE_01074 1.2e-61 ylbA S YugN-like family
HKALJCNE_01075 1.5e-166 ctaG S cytochrome c oxidase
HKALJCNE_01076 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HKALJCNE_01077 7.4e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HKALJCNE_01078 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKALJCNE_01079 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HKALJCNE_01080 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKALJCNE_01081 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HKALJCNE_01082 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKALJCNE_01083 1.7e-213 ftsW D Belongs to the SEDS family
HKALJCNE_01084 8.7e-44 ylaN S Belongs to the UPF0358 family
HKALJCNE_01085 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HKALJCNE_01086 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HKALJCNE_01087 8.9e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HKALJCNE_01088 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKALJCNE_01089 2.5e-32 ylaI S protein conserved in bacteria
HKALJCNE_01090 5.6e-47 ylaH S YlaH-like protein
HKALJCNE_01091 0.0 typA T GTP-binding protein TypA
HKALJCNE_01092 8.2e-22 S Family of unknown function (DUF5325)
HKALJCNE_01093 2.6e-37 ylaE
HKALJCNE_01094 4.5e-11 sigC S Putative zinc-finger
HKALJCNE_01095 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_01096 2.7e-42 ylaB
HKALJCNE_01097 0.0 ylaA
HKALJCNE_01098 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HKALJCNE_01099 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HKALJCNE_01100 2.9e-76 ykzC S Acetyltransferase (GNAT) family
HKALJCNE_01101 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
HKALJCNE_01102 7.1e-26 ykzI
HKALJCNE_01103 4.6e-117 yktB S Belongs to the UPF0637 family
HKALJCNE_01104 1.7e-41 yktA S Belongs to the UPF0223 family
HKALJCNE_01105 1.3e-276 speA 4.1.1.19 E Arginine
HKALJCNE_01106 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HKALJCNE_01107 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKALJCNE_01108 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKALJCNE_01109 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKALJCNE_01110 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKALJCNE_01111 1.1e-107 recN L Putative cell-wall binding lipoprotein
HKALJCNE_01113 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKALJCNE_01114 5.5e-147 ykrA S hydrolases of the HAD superfamily
HKALJCNE_01115 8.2e-31 ykzG S Belongs to the UPF0356 family
HKALJCNE_01116 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKALJCNE_01117 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKALJCNE_01118 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HKALJCNE_01119 2.5e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HKALJCNE_01120 3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKALJCNE_01121 1.5e-43 abrB K of stationary sporulation gene expression
HKALJCNE_01122 7.7e-183 mreB D Rod-share determining protein MreBH
HKALJCNE_01123 4.2e-12 S Uncharacterized protein YkpC
HKALJCNE_01124 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HKALJCNE_01125 3.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKALJCNE_01126 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKALJCNE_01127 8.1e-39 ykoA
HKALJCNE_01128 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKALJCNE_01129 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HKALJCNE_01130 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HKALJCNE_01131 3.1e-136 fruR K Transcriptional regulator
HKALJCNE_01132 6.2e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HKALJCNE_01133 7.2e-124 macB V ABC transporter, ATP-binding protein
HKALJCNE_01134 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKALJCNE_01135 2.9e-117 yknW S Yip1 domain
HKALJCNE_01136 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKALJCNE_01137 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKALJCNE_01138 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HKALJCNE_01139 1.4e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HKALJCNE_01140 1.1e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HKALJCNE_01141 1.5e-244 moeA 2.10.1.1 H molybdopterin
HKALJCNE_01142 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKALJCNE_01143 7.4e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HKALJCNE_01144 1.5e-143 yknT
HKALJCNE_01145 1.5e-93 rok K Repressor of ComK
HKALJCNE_01146 1.8e-80 ykuV CO thiol-disulfide
HKALJCNE_01147 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HKALJCNE_01148 8.8e-142 ykuT M Mechanosensitive ion channel
HKALJCNE_01149 9e-37 ykuS S Belongs to the UPF0180 family
HKALJCNE_01150 2.1e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKALJCNE_01151 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKALJCNE_01152 3.9e-78 fld C Flavodoxin
HKALJCNE_01153 5.2e-175 ykuO
HKALJCNE_01154 5.9e-85 fld C Flavodoxin domain
HKALJCNE_01155 3.5e-168 ccpC K Transcriptional regulator
HKALJCNE_01156 1.6e-76 ykuL S CBS domain
HKALJCNE_01157 3.9e-27 ykzF S Antirepressor AbbA
HKALJCNE_01158 4.4e-94 ykuK S Ribonuclease H-like
HKALJCNE_01159 3.9e-37 ykuJ S protein conserved in bacteria
HKALJCNE_01160 4.4e-233 ykuI T Diguanylate phosphodiesterase
HKALJCNE_01161 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_01162 1.4e-164 ykuE S Metallophosphoesterase
HKALJCNE_01163 1.8e-87 ykuD S protein conserved in bacteria
HKALJCNE_01164 2.8e-238 ykuC EGP Major facilitator Superfamily
HKALJCNE_01165 1.7e-84 ykyB S YkyB-like protein
HKALJCNE_01166 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HKALJCNE_01167 1.3e-15
HKALJCNE_01168 1.5e-222 patA 2.6.1.1 E Aminotransferase
HKALJCNE_01169 0.0 pilS 2.7.13.3 T Histidine kinase
HKALJCNE_01170 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HKALJCNE_01171 2.7e-119 ykwD J protein with SCP PR1 domains
HKALJCNE_01172 3.5e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HKALJCNE_01173 7.3e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HKALJCNE_01174 4.1e-257 mcpC NT chemotaxis protein
HKALJCNE_01175 3.2e-47 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKALJCNE_01176 1.9e-44 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKALJCNE_01177 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
HKALJCNE_01178 7.2e-39 splA S Transcriptional regulator
HKALJCNE_01179 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKALJCNE_01180 2.1e-39 ptsH G phosphocarrier protein HPr
HKALJCNE_01181 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKALJCNE_01182 7.6e-128 glcT K antiterminator
HKALJCNE_01184 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
HKALJCNE_01186 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HKALJCNE_01187 2.3e-09
HKALJCNE_01188 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKALJCNE_01189 4.9e-90 stoA CO thiol-disulfide
HKALJCNE_01190 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKALJCNE_01191 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
HKALJCNE_01192 2.7e-28
HKALJCNE_01193 6e-25 ykvS S protein conserved in bacteria
HKALJCNE_01194 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HKALJCNE_01195 4e-101 G Glycosyl hydrolases family 18
HKALJCNE_01196 3.5e-35 3.5.1.104 M LysM domain
HKALJCNE_01197 1.2e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
HKALJCNE_01198 3.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
HKALJCNE_01199 2e-61 ykvN K Transcriptional regulator
HKALJCNE_01200 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HKALJCNE_01201 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKALJCNE_01202 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HKALJCNE_01203 1.1e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HKALJCNE_01204 4e-179 ykvI S membrane
HKALJCNE_01205 0.0 clpE O Belongs to the ClpA ClpB family
HKALJCNE_01206 2.7e-138 motA N flagellar motor
HKALJCNE_01207 2.5e-125 motB N Flagellar motor protein
HKALJCNE_01208 1.3e-75 ykvE K transcriptional
HKALJCNE_01209 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKALJCNE_01210 6.8e-64 eag
HKALJCNE_01211 6.4e-09 S Spo0E like sporulation regulatory protein
HKALJCNE_01212 5.4e-50 XK27_09985 S Protein of unknown function (DUF1232)
HKALJCNE_01213 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HKALJCNE_01214 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HKALJCNE_01215 5.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HKALJCNE_01216 2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HKALJCNE_01217 4.4e-230 mtnE 2.6.1.83 E Aminotransferase
HKALJCNE_01218 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKALJCNE_01219 1.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HKALJCNE_01220 6.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HKALJCNE_01222 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKALJCNE_01223 0.0 kinE 2.7.13.3 T Histidine kinase
HKALJCNE_01224 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HKALJCNE_01225 4.1e-18 ykzE
HKALJCNE_01226 1.2e-10 ydfR S Protein of unknown function (DUF421)
HKALJCNE_01227 6.3e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HKALJCNE_01228 3.5e-155 htpX O Belongs to the peptidase M48B family
HKALJCNE_01229 3.3e-124 ykrK S Domain of unknown function (DUF1836)
HKALJCNE_01230 1.9e-26 sspD S small acid-soluble spore protein
HKALJCNE_01231 4e-111 rsgI S Anti-sigma factor N-terminus
HKALJCNE_01232 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKALJCNE_01233 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HKALJCNE_01234 2.7e-109 ykoX S membrane-associated protein
HKALJCNE_01235 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HKALJCNE_01236 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HKALJCNE_01237 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HKALJCNE_01238 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKALJCNE_01239 0.0 ykoS
HKALJCNE_01240 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HKALJCNE_01241 2.7e-97 ykoP G polysaccharide deacetylase
HKALJCNE_01242 4.7e-218 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HKALJCNE_01243 1.3e-81 mhqR K transcriptional
HKALJCNE_01244 6.9e-26 ykoL
HKALJCNE_01245 5.9e-18
HKALJCNE_01246 1.4e-53 tnrA K transcriptional
HKALJCNE_01247 2.2e-222 mgtE P Acts as a magnesium transporter
HKALJCNE_01250 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
HKALJCNE_01251 3.3e-113 ykoI S Peptidase propeptide and YPEB domain
HKALJCNE_01252 6.8e-243 ykoH 2.7.13.3 T Histidine kinase
HKALJCNE_01253 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_01254 5.7e-109 ykoF S YKOF-related Family
HKALJCNE_01255 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HKALJCNE_01256 1.1e-310 P ABC transporter, ATP-binding protein
HKALJCNE_01257 1.8e-136 ykoC P Cobalt transport protein
HKALJCNE_01258 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKALJCNE_01259 1.7e-176 isp O Belongs to the peptidase S8 family
HKALJCNE_01260 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKALJCNE_01261 1.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HKALJCNE_01262 1.9e-71 ohrB O Organic hydroperoxide resistance protein
HKALJCNE_01263 4.4e-74 ohrR K COG1846 Transcriptional regulators
HKALJCNE_01264 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HKALJCNE_01265 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKALJCNE_01266 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKALJCNE_01267 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HKALJCNE_01268 7e-50 ykkD P Multidrug resistance protein
HKALJCNE_01269 3.5e-55 ykkC P Multidrug resistance protein
HKALJCNE_01270 2.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKALJCNE_01271 2e-97 ykkA S Protein of unknown function (DUF664)
HKALJCNE_01272 2.7e-129 ykjA S Protein of unknown function (DUF421)
HKALJCNE_01273 1e-10
HKALJCNE_01274 3.9e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HKALJCNE_01275 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HKALJCNE_01276 2e-160 ykgA E Amidinotransferase
HKALJCNE_01277 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HKALJCNE_01278 4.7e-185 ykfD E Belongs to the ABC transporter superfamily
HKALJCNE_01279 1.1e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKALJCNE_01280 2.8e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKALJCNE_01281 5.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HKALJCNE_01283 0.0 dppE E ABC transporter substrate-binding protein
HKALJCNE_01284 1.1e-184 dppD P Belongs to the ABC transporter superfamily
HKALJCNE_01285 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKALJCNE_01286 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKALJCNE_01287 3.3e-152 dppA E D-aminopeptidase
HKALJCNE_01288 3.4e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HKALJCNE_01289 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKALJCNE_01291 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKALJCNE_01292 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKALJCNE_01293 1.4e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HKALJCNE_01294 1.2e-239 steT E amino acid
HKALJCNE_01295 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKALJCNE_01296 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKALJCNE_01297 1.8e-37 yaaB S Domain of unknown function (DUF370)
HKALJCNE_01298 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKALJCNE_01299 2.4e-33 yaaA S S4 domain
HKALJCNE_01300 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKALJCNE_01301 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKALJCNE_01302 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKALJCNE_01303 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKALJCNE_01304 6.5e-108 jag S single-stranded nucleic acid binding R3H
HKALJCNE_01305 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKALJCNE_01306 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKALJCNE_01307 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HKALJCNE_01308 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HKALJCNE_01309 3.1e-72 S Bacterial PH domain
HKALJCNE_01310 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HKALJCNE_01311 2.1e-149 spo0J K Belongs to the ParB family
HKALJCNE_01312 2.8e-111 yyaC S Sporulation protein YyaC
HKALJCNE_01313 5.2e-176 yyaD S Membrane
HKALJCNE_01314 2.3e-33 yyzM S protein conserved in bacteria
HKALJCNE_01315 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKALJCNE_01316 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKALJCNE_01317 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HKALJCNE_01318 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKALJCNE_01319 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKALJCNE_01320 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
HKALJCNE_01321 8.1e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HKALJCNE_01322 1.7e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKALJCNE_01323 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HKALJCNE_01324 2.7e-244 EGP Major facilitator superfamily
HKALJCNE_01325 3.6e-168 yyaK S CAAX protease self-immunity
HKALJCNE_01326 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HKALJCNE_01327 2.9e-157 yyaM EG EamA-like transporter family
HKALJCNE_01328 1.5e-60 yyaN K MerR HTH family regulatory protein
HKALJCNE_01329 6.7e-22 yyaR K acetyltransferase
HKALJCNE_01330 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
HKALJCNE_01331 5.4e-67 yyaQ S YjbR
HKALJCNE_01332 8.4e-93 yyaR K Acetyltransferase (GNAT) domain
HKALJCNE_01333 1.9e-96 yyaS S Membrane
HKALJCNE_01334 3.5e-71 yjcF S Acetyltransferase (GNAT) domain
HKALJCNE_01335 5.6e-77 yybA 2.3.1.57 K transcriptional
HKALJCNE_01336 6.6e-127 S Metallo-beta-lactamase superfamily
HKALJCNE_01337 5.7e-52 yybH S SnoaL-like domain
HKALJCNE_01338 5.8e-122
HKALJCNE_01339 1.3e-110 K TipAS antibiotic-recognition domain
HKALJCNE_01340 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HKALJCNE_01342 2.5e-69
HKALJCNE_01343 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HKALJCNE_01344 1.4e-68 ydeP3 K Transcriptional regulator
HKALJCNE_01345 3.9e-84 cotF M Spore coat protein
HKALJCNE_01347 2.9e-160 yybS S membrane
HKALJCNE_01348 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKALJCNE_01349 2.2e-73 rplI J binds to the 23S rRNA
HKALJCNE_01350 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKALJCNE_01351 8.4e-221 yeaN P COG2807 Cyanate permease
HKALJCNE_01352 1.9e-15 yycC K YycC-like protein
HKALJCNE_01354 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HKALJCNE_01355 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKALJCNE_01356 1.3e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKALJCNE_01357 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKALJCNE_01359 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HKALJCNE_01360 7.1e-86 ybbJ J acetyltransferase
HKALJCNE_01361 4.6e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKALJCNE_01362 2.5e-150 ybbH K transcriptional
HKALJCNE_01363 6.4e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKALJCNE_01364 9.2e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HKALJCNE_01365 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HKALJCNE_01366 1.9e-236 ybbC 3.2.1.52 S protein conserved in bacteria
HKALJCNE_01367 4e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HKALJCNE_01368 7.5e-164 feuA P Iron-uptake system-binding protein
HKALJCNE_01369 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_01370 1.1e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_01371 1.2e-137 ybbA S Putative esterase
HKALJCNE_01372 1.7e-160 ybaS 1.1.1.58 S Na -dependent transporter
HKALJCNE_01374 6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HKALJCNE_01376 5.5e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKALJCNE_01377 3.8e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HKALJCNE_01378 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HKALJCNE_01379 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKALJCNE_01380 8.8e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKALJCNE_01381 0.0 ydiF S ABC transporter
HKALJCNE_01382 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HKALJCNE_01383 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKALJCNE_01384 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKALJCNE_01385 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKALJCNE_01386 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HKALJCNE_01387 1.3e-128 ydiL S CAAX protease self-immunity
HKALJCNE_01388 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKALJCNE_01389 2.8e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKALJCNE_01390 6.2e-153 ydjC S Abhydrolase domain containing 18
HKALJCNE_01391 0.0 K NB-ARC domain
HKALJCNE_01392 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
HKALJCNE_01393 6.7e-254 gutA G MFS/sugar transport protein
HKALJCNE_01394 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HKALJCNE_01395 1.1e-113 pspA KT Phage shock protein A
HKALJCNE_01396 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKALJCNE_01397 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HKALJCNE_01398 1.3e-147 ydjI S virion core protein (lumpy skin disease virus)
HKALJCNE_01399 7e-189 S Ion transport 2 domain protein
HKALJCNE_01400 3.9e-257 iolT EGP Major facilitator Superfamily
HKALJCNE_01401 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HKALJCNE_01402 4.5e-64 ydjM M Lytic transglycolase
HKALJCNE_01403 3.7e-156 ydjN U Involved in the tonB-independent uptake of proteins
HKALJCNE_01405 1.2e-34 ydjO S Cold-inducible protein YdjO
HKALJCNE_01406 3.4e-157 ydjP I Alpha/beta hydrolase family
HKALJCNE_01407 1.6e-177 yeaA S Protein of unknown function (DUF4003)
HKALJCNE_01408 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HKALJCNE_01409 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HKALJCNE_01410 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKALJCNE_01411 4.3e-175 yeaC S COG0714 MoxR-like ATPases
HKALJCNE_01412 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HKALJCNE_01413 0.0 yebA E COG1305 Transglutaminase-like enzymes
HKALJCNE_01414 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKALJCNE_01415 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_01416 1.3e-255 S Domain of unknown function (DUF4179)
HKALJCNE_01417 1e-211 pbuG S permease
HKALJCNE_01418 4.4e-117 yebC M Membrane
HKALJCNE_01420 8.9e-93 yebE S UPF0316 protein
HKALJCNE_01421 8e-28 yebG S NETI protein
HKALJCNE_01422 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKALJCNE_01423 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKALJCNE_01424 8.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKALJCNE_01425 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKALJCNE_01426 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKALJCNE_01427 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKALJCNE_01428 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKALJCNE_01429 3.6e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKALJCNE_01430 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HKALJCNE_01431 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKALJCNE_01432 3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKALJCNE_01433 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
HKALJCNE_01434 1e-72 K helix_turn_helix ASNC type
HKALJCNE_01435 2.2e-16 yjeH E Amino acid permease
HKALJCNE_01436 5.9e-200 yjeH E Amino acid permease
HKALJCNE_01437 2.7e-27 S Protein of unknown function (DUF2892)
HKALJCNE_01438 0.0 yerA 3.5.4.2 F adenine deaminase
HKALJCNE_01439 1.7e-187 yerB S Protein of unknown function (DUF3048) C-terminal domain
HKALJCNE_01440 4.8e-51 yerC S protein conserved in bacteria
HKALJCNE_01441 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HKALJCNE_01443 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HKALJCNE_01444 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKALJCNE_01445 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKALJCNE_01446 2e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
HKALJCNE_01447 3.2e-197 yerI S homoserine kinase type II (protein kinase fold)
HKALJCNE_01448 1.6e-123 sapB S MgtC SapB transporter
HKALJCNE_01449 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKALJCNE_01450 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKALJCNE_01451 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKALJCNE_01452 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKALJCNE_01453 7.6e-144 yerO K Transcriptional regulator
HKALJCNE_01454 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKALJCNE_01455 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKALJCNE_01456 1.7e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKALJCNE_01460 2.4e-100 S response regulator aspartate phosphatase
HKALJCNE_01462 5.1e-42 S Immunity protein 22
HKALJCNE_01463 1.1e-187 yobL S Bacterial EndoU nuclease
HKALJCNE_01465 2.2e-96 L endonuclease activity
HKALJCNE_01466 6.1e-164 3.4.24.40 CO amine dehydrogenase activity
HKALJCNE_01467 8.5e-207 S Tetratricopeptide repeat
HKALJCNE_01469 2.7e-126 yeeN K transcriptional regulatory protein
HKALJCNE_01471 2.1e-100 dhaR3 K Transcriptional regulator
HKALJCNE_01472 3.4e-79 yesE S SnoaL-like domain
HKALJCNE_01473 4.9e-151 yesF GM NAD(P)H-binding
HKALJCNE_01474 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HKALJCNE_01475 1.5e-45 cotJB S CotJB protein
HKALJCNE_01476 5.2e-104 cotJC P Spore Coat
HKALJCNE_01477 7.9e-102 yesJ K Acetyltransferase (GNAT) family
HKALJCNE_01479 1.8e-102 yesL S Protein of unknown function, DUF624
HKALJCNE_01480 0.0 yesM 2.7.13.3 T Histidine kinase
HKALJCNE_01481 6.1e-202 yesN K helix_turn_helix, arabinose operon control protein
HKALJCNE_01482 1.8e-245 yesO G Bacterial extracellular solute-binding protein
HKALJCNE_01483 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HKALJCNE_01484 3.5e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HKALJCNE_01485 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HKALJCNE_01486 0.0 yesS K Transcriptional regulator
HKALJCNE_01487 3.7e-128 E GDSL-like Lipase/Acylhydrolase
HKALJCNE_01488 2.3e-127 yesU S Domain of unknown function (DUF1961)
HKALJCNE_01489 5.2e-113 yesV S Protein of unknown function, DUF624
HKALJCNE_01490 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HKALJCNE_01491 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HKALJCNE_01492 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HKALJCNE_01493 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HKALJCNE_01494 0.0 yetA
HKALJCNE_01495 1.2e-288 lplA G Bacterial extracellular solute-binding protein
HKALJCNE_01496 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HKALJCNE_01497 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HKALJCNE_01498 1.6e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HKALJCNE_01499 5.2e-122 yetF S membrane
HKALJCNE_01500 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HKALJCNE_01501 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKALJCNE_01502 2.4e-34
HKALJCNE_01503 7.1e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKALJCNE_01504 5.8e-19 yezD S Uncharacterized small protein (DUF2292)
HKALJCNE_01505 5.3e-105 yetJ S Belongs to the BI1 family
HKALJCNE_01506 2.3e-157 yetK EG EamA-like transporter family
HKALJCNE_01507 2.1e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_01508 3e-209 yetM CH FAD binding domain
HKALJCNE_01510 3e-193 yetN S Protein of unknown function (DUF3900)
HKALJCNE_01511 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HKALJCNE_01512 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKALJCNE_01513 7.4e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
HKALJCNE_01514 3.2e-172 yfnG 4.2.1.45 M dehydratase
HKALJCNE_01515 1.1e-177 yfnF M Nucleotide-diphospho-sugar transferase
HKALJCNE_01516 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HKALJCNE_01517 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
HKALJCNE_01518 4.8e-113 fsr P COG0477 Permeases of the major facilitator superfamily
HKALJCNE_01519 1.1e-78 fsr P COG0477 Permeases of the major facilitator superfamily
HKALJCNE_01520 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKALJCNE_01521 6.4e-241 yfnA E amino acid
HKALJCNE_01522 1.8e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKALJCNE_01523 1.1e-113 yfmS NT chemotaxis protein
HKALJCNE_01524 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKALJCNE_01525 1.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HKALJCNE_01526 2.6e-68 yfmP K transcriptional
HKALJCNE_01527 1.5e-209 yfmO EGP Major facilitator Superfamily
HKALJCNE_01528 1.6e-59 isp O Subtilase family
HKALJCNE_01529 6.4e-19
HKALJCNE_01531 6.3e-57
HKALJCNE_01532 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKALJCNE_01533 4.5e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HKALJCNE_01534 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
HKALJCNE_01535 1.7e-185 yfmJ S N-terminal domain of oxidoreductase
HKALJCNE_01536 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HKALJCNE_01537 2.8e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_01538 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_01539 2.5e-167 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HKALJCNE_01540 2.9e-24 S Protein of unknown function (DUF3212)
HKALJCNE_01541 6.5e-57 yflT S Heat induced stress protein YflT
HKALJCNE_01542 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HKALJCNE_01543 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
HKALJCNE_01544 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKALJCNE_01545 2.2e-117 citT T response regulator
HKALJCNE_01546 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
HKALJCNE_01547 4.2e-226 citM C Citrate transporter
HKALJCNE_01548 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HKALJCNE_01549 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HKALJCNE_01550 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKALJCNE_01551 3.2e-121 yflK S protein conserved in bacteria
HKALJCNE_01552 8.9e-18 yflJ S Protein of unknown function (DUF2639)
HKALJCNE_01553 4.1e-19 yflI
HKALJCNE_01554 2.4e-50 yflH S Protein of unknown function (DUF3243)
HKALJCNE_01555 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HKALJCNE_01556 3.3e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HKALJCNE_01557 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKALJCNE_01558 6e-67 yhdN S Domain of unknown function (DUF1992)
HKALJCNE_01559 2.2e-252 agcS_1 E Sodium alanine symporter
HKALJCNE_01560 1.9e-192 E Spore germination protein
HKALJCNE_01562 2.5e-206 yfkR S spore germination
HKALJCNE_01563 9.9e-283 yfkQ EG Spore germination protein
HKALJCNE_01564 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKALJCNE_01565 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HKALJCNE_01566 6.7e-133 treR K transcriptional
HKALJCNE_01567 1.4e-124 yfkO C nitroreductase
HKALJCNE_01568 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HKALJCNE_01569 2.8e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
HKALJCNE_01570 8.9e-207 ydiM EGP Major facilitator Superfamily
HKALJCNE_01571 2.1e-29 yfkK S Belongs to the UPF0435 family
HKALJCNE_01572 3.9e-72 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKALJCNE_01573 2.4e-50 yfkI S gas vesicle protein
HKALJCNE_01574 1.3e-143 yihY S Belongs to the UPF0761 family
HKALJCNE_01575 5e-08
HKALJCNE_01576 2e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HKALJCNE_01577 6.1e-183 cax P COG0387 Ca2 H antiporter
HKALJCNE_01578 1.2e-146 yfkD S YfkD-like protein
HKALJCNE_01579 6e-149 yfkC M Mechanosensitive ion channel
HKALJCNE_01580 5.4e-222 yfkA S YfkB-like domain
HKALJCNE_01581 1.1e-26 yfjT
HKALJCNE_01582 2.6e-154 pdaA G deacetylase
HKALJCNE_01583 2.7e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HKALJCNE_01584 3.2e-183 corA P Mediates influx of magnesium ions
HKALJCNE_01585 7.2e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKALJCNE_01586 1.2e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKALJCNE_01587 1.7e-42 S YfzA-like protein
HKALJCNE_01588 1.5e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKALJCNE_01589 3.6e-84 yfjM S Psort location Cytoplasmic, score
HKALJCNE_01590 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKALJCNE_01591 1.9e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKALJCNE_01592 1.3e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKALJCNE_01593 4.3e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKALJCNE_01594 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HKALJCNE_01595 1.2e-25 sspH S Belongs to the SspH family
HKALJCNE_01596 4e-56 yfjF S UPF0060 membrane protein
HKALJCNE_01597 1.4e-85 S Family of unknown function (DUF5381)
HKALJCNE_01598 1.2e-124 yfjC
HKALJCNE_01599 9.6e-172 yfjB
HKALJCNE_01600 5.7e-44 yfjA S Belongs to the WXG100 family
HKALJCNE_01601 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKALJCNE_01602 1e-139 glvR K Helix-turn-helix domain, rpiR family
HKALJCNE_01603 8e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKALJCNE_01604 0.0 yobO M COG5434 Endopolygalacturonase
HKALJCNE_01605 6.8e-309 yfiB3 V ABC transporter
HKALJCNE_01606 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKALJCNE_01607 6.4e-64 mhqP S DoxX
HKALJCNE_01608 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HKALJCNE_01610 3.6e-213 yxjM T Histidine kinase
HKALJCNE_01611 1.6e-112 KT LuxR family transcriptional regulator
HKALJCNE_01612 1.9e-167 V ABC transporter, ATP-binding protein
HKALJCNE_01613 6.6e-210 V ABC-2 family transporter protein
HKALJCNE_01614 4.4e-203 V COG0842 ABC-type multidrug transport system, permease component
HKALJCNE_01615 8.3e-99 padR K transcriptional
HKALJCNE_01616 1.3e-246 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_01617 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HKALJCNE_01618 2.9e-139 srfAD Q thioesterase
HKALJCNE_01619 2.6e-225 EGP Major Facilitator Superfamily
HKALJCNE_01620 8.7e-88 S YcxB-like protein
HKALJCNE_01621 6.4e-160 ycxC EG EamA-like transporter family
HKALJCNE_01622 2.7e-252 ycxD K GntR family transcriptional regulator
HKALJCNE_01623 1.7e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HKALJCNE_01624 1.7e-114 yczE S membrane
HKALJCNE_01625 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKALJCNE_01626 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HKALJCNE_01627 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HKALJCNE_01628 1.9e-161 bsdA K LysR substrate binding domain
HKALJCNE_01629 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKALJCNE_01630 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HKALJCNE_01631 4e-39 bsdD 4.1.1.61 S response to toxic substance
HKALJCNE_01632 3.5e-82 yclD
HKALJCNE_01633 1.6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
HKALJCNE_01634 9.2e-262 dtpT E amino acid peptide transporter
HKALJCNE_01635 2.5e-298 yclG M Pectate lyase superfamily protein
HKALJCNE_01637 3.5e-278 gerKA EG Spore germination protein
HKALJCNE_01638 2.8e-224 gerKC S spore germination
HKALJCNE_01639 1.2e-192 gerKB F Spore germination protein
HKALJCNE_01640 1.6e-120 yclH P ABC transporter
HKALJCNE_01641 7.6e-200 yclI V ABC transporter (permease) YclI
HKALJCNE_01642 4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_01643 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HKALJCNE_01644 2e-70 S aspartate phosphatase
HKALJCNE_01648 3.8e-238 lysC 2.7.2.4 E Belongs to the aspartokinase family
HKALJCNE_01649 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_01650 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_01651 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HKALJCNE_01652 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HKALJCNE_01653 7e-251 ycnB EGP Major facilitator Superfamily
HKALJCNE_01654 6.5e-154 ycnC K Transcriptional regulator
HKALJCNE_01655 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HKALJCNE_01656 5.2e-44 ycnE S Monooxygenase
HKALJCNE_01657 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HKALJCNE_01658 4.3e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKALJCNE_01659 2.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKALJCNE_01660 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKALJCNE_01661 4e-148 glcU U Glucose uptake
HKALJCNE_01662 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_01663 1.4e-99 ycnI S protein conserved in bacteria
HKALJCNE_01664 1.2e-307 ycnJ P protein, homolog of Cu resistance protein CopC
HKALJCNE_01665 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HKALJCNE_01666 3.4e-53
HKALJCNE_01667 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HKALJCNE_01668 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HKALJCNE_01669 1.2e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HKALJCNE_01670 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HKALJCNE_01671 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKALJCNE_01672 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKALJCNE_01673 2.8e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HKALJCNE_01674 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HKALJCNE_01676 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKALJCNE_01677 2.3e-139 ycsF S Belongs to the UPF0271 (lamB) family
HKALJCNE_01678 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HKALJCNE_01679 9e-147 ycsI S Belongs to the D-glutamate cyclase family
HKALJCNE_01680 5.2e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HKALJCNE_01681 8.7e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HKALJCNE_01682 2.7e-132 kipR K Transcriptional regulator
HKALJCNE_01683 2.3e-116 ycsK E anatomical structure formation involved in morphogenesis
HKALJCNE_01685 5.4e-49 yczJ S biosynthesis
HKALJCNE_01686 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HKALJCNE_01687 1.2e-171 ydhF S Oxidoreductase
HKALJCNE_01688 0.0 mtlR K transcriptional regulator, MtlR
HKALJCNE_01689 3e-292 ydaB IQ acyl-CoA ligase
HKALJCNE_01690 4.5e-98 ydaC Q Methyltransferase domain
HKALJCNE_01691 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_01692 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HKALJCNE_01693 5.6e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKALJCNE_01694 6.8e-77 ydaG 1.4.3.5 S general stress protein
HKALJCNE_01695 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HKALJCNE_01696 3.3e-46 ydzA EGP Major facilitator Superfamily
HKALJCNE_01697 2.5e-74 lrpC K Transcriptional regulator
HKALJCNE_01698 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKALJCNE_01699 2.6e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HKALJCNE_01700 1.4e-150 ydaK T Diguanylate cyclase, GGDEF domain
HKALJCNE_01701 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HKALJCNE_01702 1.3e-232 ydaM M Glycosyl transferase family group 2
HKALJCNE_01703 0.0 ydaN S Bacterial cellulose synthase subunit
HKALJCNE_01704 0.0 ydaO E amino acid
HKALJCNE_01705 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HKALJCNE_01706 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKALJCNE_01707 9.4e-40
HKALJCNE_01708 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HKALJCNE_01710 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HKALJCNE_01711 3.2e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HKALJCNE_01713 8.3e-57 ydbB G Cupin domain
HKALJCNE_01714 6.9e-62 ydbC S Domain of unknown function (DUF4937
HKALJCNE_01715 3.5e-154 ydbD P Catalase
HKALJCNE_01716 1.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HKALJCNE_01717 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKALJCNE_01718 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HKALJCNE_01719 1.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKALJCNE_01720 9.7e-181 ydbI S AI-2E family transporter
HKALJCNE_01721 8.9e-170 ydbJ V ABC transporter, ATP-binding protein
HKALJCNE_01722 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKALJCNE_01723 2.7e-52 ydbL
HKALJCNE_01724 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HKALJCNE_01725 1.1e-18 S Fur-regulated basic protein B
HKALJCNE_01726 2.2e-07 S Fur-regulated basic protein A
HKALJCNE_01727 5.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKALJCNE_01728 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKALJCNE_01729 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKALJCNE_01730 1e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKALJCNE_01731 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKALJCNE_01732 2.1e-82 ydbS S Bacterial PH domain
HKALJCNE_01733 8.6e-260 ydbT S Membrane
HKALJCNE_01734 7e-110 pstA P Phosphate transport system permease
HKALJCNE_01735 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKALJCNE_01736 4.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKALJCNE_01737 7.3e-72 yqzC S YceG-like family
HKALJCNE_01738 3.5e-50 yqzD
HKALJCNE_01740 3.1e-198 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HKALJCNE_01741 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKALJCNE_01742 3.3e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKALJCNE_01743 2.5e-09 yqgO
HKALJCNE_01744 5.2e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HKALJCNE_01745 3.1e-33 yqgQ S Protein conserved in bacteria
HKALJCNE_01746 5.2e-181 glcK 2.7.1.2 G Glucokinase
HKALJCNE_01747 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKALJCNE_01748 4.3e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HKALJCNE_01749 3.9e-198 yqgU
HKALJCNE_01750 6.9e-50 yqgV S Thiamine-binding protein
HKALJCNE_01751 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HKALJCNE_01752 6.8e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HKALJCNE_01753 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HKALJCNE_01754 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HKALJCNE_01756 3.2e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKALJCNE_01757 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKALJCNE_01758 7.2e-175 corA P Mg2 transporter protein
HKALJCNE_01759 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKALJCNE_01760 1.7e-174 comGB NU COG1459 Type II secretory pathway, component PulF
HKALJCNE_01761 1.4e-47 comGC U Required for transformation and DNA binding
HKALJCNE_01762 1.2e-68 gspH NU protein transport across the cell outer membrane
HKALJCNE_01763 7.6e-58 comGE
HKALJCNE_01764 1.3e-34 comGF U Putative Competence protein ComGF
HKALJCNE_01765 3.4e-43 S ComG operon protein 7
HKALJCNE_01766 3.1e-26 yqzE S YqzE-like protein
HKALJCNE_01767 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HKALJCNE_01768 1.3e-113 yqxM
HKALJCNE_01769 2.5e-58 sipW 3.4.21.89 U Signal peptidase
HKALJCNE_01770 1.2e-140 tasA S Cell division protein FtsN
HKALJCNE_01771 1e-54 sinR K transcriptional
HKALJCNE_01772 1.2e-24 sinI S Anti-repressor SinI
HKALJCNE_01773 2.1e-151 yqhG S Bacterial protein YqhG of unknown function
HKALJCNE_01774 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKALJCNE_01775 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HKALJCNE_01776 9.3e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKALJCNE_01777 1e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKALJCNE_01778 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HKALJCNE_01779 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HKALJCNE_01780 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HKALJCNE_01781 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HKALJCNE_01782 2.2e-61 yqhP
HKALJCNE_01783 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
HKALJCNE_01784 2.3e-93 yqhR S Conserved membrane protein YqhR
HKALJCNE_01785 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HKALJCNE_01786 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HKALJCNE_01787 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKALJCNE_01788 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HKALJCNE_01789 4e-170 spoIIIAA S stage III sporulation protein AA
HKALJCNE_01790 4.1e-84 spoIIIAB S Stage III sporulation protein
HKALJCNE_01791 7.6e-29 spoIIIAC S stage III sporulation protein AC
HKALJCNE_01792 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HKALJCNE_01793 2.2e-197 spoIIIAE S stage III sporulation protein AE
HKALJCNE_01794 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HKALJCNE_01795 2.2e-109 spoIIIAG S stage III sporulation protein AG
HKALJCNE_01796 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HKALJCNE_01797 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKALJCNE_01798 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKALJCNE_01799 2.1e-67 yqhY S protein conserved in bacteria
HKALJCNE_01800 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKALJCNE_01801 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKALJCNE_01802 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKALJCNE_01803 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKALJCNE_01804 1.1e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKALJCNE_01805 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKALJCNE_01806 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HKALJCNE_01807 1.1e-77 argR K Regulates arginine biosynthesis genes
HKALJCNE_01808 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
HKALJCNE_01809 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HKALJCNE_01810 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HKALJCNE_01812 8e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HKALJCNE_01813 5.9e-27
HKALJCNE_01814 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HKALJCNE_01815 1.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKALJCNE_01816 2.2e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
HKALJCNE_01817 3.4e-155 hbdA 1.1.1.157 I Dehydrogenase
HKALJCNE_01818 2e-211 mmgC I acyl-CoA dehydrogenase
HKALJCNE_01819 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HKALJCNE_01820 4.5e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HKALJCNE_01821 2.3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HKALJCNE_01822 4e-34 yqzF S Protein of unknown function (DUF2627)
HKALJCNE_01823 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HKALJCNE_01824 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HKALJCNE_01825 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKALJCNE_01826 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HKALJCNE_01827 8.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKALJCNE_01828 5.5e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKALJCNE_01829 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKALJCNE_01830 1.2e-217 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKALJCNE_01831 7.5e-152 bmrR K helix_turn_helix, mercury resistance
HKALJCNE_01832 7.9e-208 norA EGP Major facilitator Superfamily
HKALJCNE_01833 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKALJCNE_01834 9.3e-77 yqiW S Belongs to the UPF0403 family
HKALJCNE_01835 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
HKALJCNE_01836 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HKALJCNE_01837 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKALJCNE_01838 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
HKALJCNE_01839 3e-98 yqjB S protein conserved in bacteria
HKALJCNE_01841 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HKALJCNE_01842 3.6e-285 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKALJCNE_01843 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HKALJCNE_01844 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
HKALJCNE_01845 1.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKALJCNE_01846 4.5e-24 yqzJ
HKALJCNE_01847 1.1e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKALJCNE_01848 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKALJCNE_01849 3.3e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKALJCNE_01850 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKALJCNE_01851 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKALJCNE_01852 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKALJCNE_01853 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HKALJCNE_01854 0.0 rocB E arginine degradation protein
HKALJCNE_01855 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKALJCNE_01856 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HKALJCNE_01857 2.9e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_01858 5.4e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HKALJCNE_01859 7e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HKALJCNE_01860 4.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKALJCNE_01862 3.8e-224 yqjV G Major Facilitator Superfamily
HKALJCNE_01864 2.9e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKALJCNE_01865 1.7e-49 S YolD-like protein
HKALJCNE_01866 1.8e-86 yqjY K acetyltransferase
HKALJCNE_01867 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HKALJCNE_01868 2.8e-193 yqkA K GrpB protein
HKALJCNE_01869 2.8e-54 yqkB S Belongs to the HesB IscA family
HKALJCNE_01870 4.6e-38 yqkC S Protein of unknown function (DUF2552)
HKALJCNE_01871 3.9e-170 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HKALJCNE_01872 3.1e-12 yqkE S Protein of unknown function (DUF3886)
HKALJCNE_01873 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HKALJCNE_01875 8.1e-238 lytS 2.7.13.3 T Histidine kinase
HKALJCNE_01876 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
HKALJCNE_01877 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HKALJCNE_01878 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HKALJCNE_01880 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKALJCNE_01881 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKALJCNE_01882 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKALJCNE_01883 7.5e-45 ysdA S Membrane
HKALJCNE_01884 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HKALJCNE_01885 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HKALJCNE_01886 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HKALJCNE_01887 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HKALJCNE_01888 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HKALJCNE_01889 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HKALJCNE_01890 1.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HKALJCNE_01891 7.5e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HKALJCNE_01892 6.2e-254 araN G carbohydrate transport
HKALJCNE_01893 4.2e-167 araP G carbohydrate transport
HKALJCNE_01894 3.4e-144 araQ G transport system permease
HKALJCNE_01895 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HKALJCNE_01896 0.0 cstA T Carbon starvation protein
HKALJCNE_01897 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HKALJCNE_01898 1.4e-256 glcF C Glycolate oxidase
HKALJCNE_01899 1.1e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
HKALJCNE_01900 2.9e-204 ysfB KT regulator
HKALJCNE_01901 5.8e-32 sspI S Belongs to the SspI family
HKALJCNE_01902 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKALJCNE_01903 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKALJCNE_01904 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKALJCNE_01905 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKALJCNE_01906 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKALJCNE_01907 1.3e-85 cvpA S membrane protein, required for colicin V production
HKALJCNE_01908 0.0 polX L COG1796 DNA polymerase IV (family X)
HKALJCNE_01909 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKALJCNE_01910 7.3e-68 yshE S membrane
HKALJCNE_01911 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKALJCNE_01912 4e-99 fadR K Transcriptional regulator
HKALJCNE_01913 7.8e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HKALJCNE_01914 4.5e-135 etfB C Electron transfer flavoprotein
HKALJCNE_01915 2.1e-177 etfA C Electron transfer flavoprotein
HKALJCNE_01917 2.8e-303 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HKALJCNE_01918 2e-52 trxA O Belongs to the thioredoxin family
HKALJCNE_01919 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKALJCNE_01920 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HKALJCNE_01921 1.2e-79 yslB S Protein of unknown function (DUF2507)
HKALJCNE_01922 2.7e-106 sdhC C succinate dehydrogenase
HKALJCNE_01923 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HKALJCNE_01924 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HKALJCNE_01925 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HKALJCNE_01926 3.3e-30 gerE K Transcriptional regulator
HKALJCNE_01927 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_01928 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKALJCNE_01929 7.2e-195 gerM S COG5401 Spore germination protein
HKALJCNE_01930 9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKALJCNE_01931 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKALJCNE_01932 5.3e-92 ysnB S Phosphoesterase
HKALJCNE_01934 1.7e-132 ysnF S protein conserved in bacteria
HKALJCNE_01935 3.1e-75 ysnE K acetyltransferase
HKALJCNE_01937 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HKALJCNE_01938 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HKALJCNE_01939 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKALJCNE_01940 7.1e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKALJCNE_01941 1.3e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKALJCNE_01942 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKALJCNE_01943 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKALJCNE_01944 1.1e-186 ysoA H Tetratricopeptide repeat
HKALJCNE_01945 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKALJCNE_01946 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKALJCNE_01947 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HKALJCNE_01948 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HKALJCNE_01949 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HKALJCNE_01950 1.4e-89 ysxD
HKALJCNE_01951 1.9e-245 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HKALJCNE_01952 3.6e-146 hemX O cytochrome C
HKALJCNE_01953 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HKALJCNE_01954 7.9e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKALJCNE_01955 6.2e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HKALJCNE_01956 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HKALJCNE_01957 5.4e-221 spoVID M stage VI sporulation protein D
HKALJCNE_01958 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HKALJCNE_01959 1.6e-25
HKALJCNE_01960 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKALJCNE_01961 1.4e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKALJCNE_01962 2.8e-126 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HKALJCNE_01963 6.4e-166 spoIIB S Sporulation related domain
HKALJCNE_01964 2.8e-102 maf D septum formation protein Maf
HKALJCNE_01965 6.5e-125 radC E Belongs to the UPF0758 family
HKALJCNE_01966 1.8e-184 mreB D Rod shape-determining protein MreB
HKALJCNE_01967 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HKALJCNE_01968 1.6e-83 mreD M shape-determining protein
HKALJCNE_01969 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKALJCNE_01970 8e-143 minD D Belongs to the ParA family
HKALJCNE_01971 1.4e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HKALJCNE_01972 9.2e-161 spoIVFB S Stage IV sporulation protein
HKALJCNE_01973 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKALJCNE_01974 1e-54 ysxB J ribosomal protein
HKALJCNE_01975 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKALJCNE_01976 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HKALJCNE_01977 7.3e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKALJCNE_01978 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HKALJCNE_01979 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HKALJCNE_01980 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HKALJCNE_01981 1.9e-228 nifS 2.8.1.7 E Cysteine desulfurase
HKALJCNE_01982 6e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HKALJCNE_01983 4e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HKALJCNE_01984 4.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HKALJCNE_01985 8.3e-157 safA M spore coat assembly protein SafA
HKALJCNE_01986 3.5e-50 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKALJCNE_01987 5.5e-127 yebC K transcriptional regulatory protein
HKALJCNE_01988 3.1e-262 alsT E Sodium alanine symporter
HKALJCNE_01990 5.6e-51 S Family of unknown function (DUF5412)
HKALJCNE_01992 1.9e-118 yrzF T serine threonine protein kinase
HKALJCNE_01993 8.2e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HKALJCNE_01994 2.6e-252 csbX EGP Major facilitator Superfamily
HKALJCNE_01995 4.8e-93 bofC S BofC C-terminal domain
HKALJCNE_01996 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKALJCNE_01997 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKALJCNE_01998 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HKALJCNE_01999 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKALJCNE_02000 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKALJCNE_02001 8e-39 yajC U Preprotein translocase subunit YajC
HKALJCNE_02002 2.2e-73 yrzE S Protein of unknown function (DUF3792)
HKALJCNE_02003 1.3e-111 yrbG S membrane
HKALJCNE_02004 1.2e-267 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKALJCNE_02005 1.6e-48 yrzD S Post-transcriptional regulator
HKALJCNE_02006 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKALJCNE_02007 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HKALJCNE_02008 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HKALJCNE_02009 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKALJCNE_02010 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKALJCNE_02011 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKALJCNE_02012 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKALJCNE_02013 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
HKALJCNE_02015 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKALJCNE_02016 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKALJCNE_02017 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HKALJCNE_02018 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HKALJCNE_02019 1.2e-70 cymR K Transcriptional regulator
HKALJCNE_02020 4.8e-210 iscS 2.8.1.7 E Cysteine desulfurase
HKALJCNE_02021 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKALJCNE_02022 1.4e-15 S COG0457 FOG TPR repeat
HKALJCNE_02023 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKALJCNE_02024 1.2e-82 yrrD S protein conserved in bacteria
HKALJCNE_02025 9.8e-31 yrzR
HKALJCNE_02026 8e-08 S Protein of unknown function (DUF3918)
HKALJCNE_02027 7.6e-107 glnP P ABC transporter
HKALJCNE_02028 8e-109 gluC P ABC transporter
HKALJCNE_02029 4.4e-86 glnH ET Belongs to the bacterial solute-binding protein 3 family
HKALJCNE_02030 3.4e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKALJCNE_02031 2.5e-53 S Domain of unknown function (DUF4181)
HKALJCNE_02032 8.8e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HKALJCNE_02033 8e-82 ywrC K Transcriptional regulator
HKALJCNE_02034 3.5e-103 ywrB P Chromate transporter
HKALJCNE_02035 6.4e-88 ywrA P COG2059 Chromate transport protein ChrA
HKALJCNE_02037 3.3e-100 ywqN S NAD(P)H-dependent
HKALJCNE_02038 1.4e-161 K Transcriptional regulator
HKALJCNE_02039 2.6e-121 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HKALJCNE_02040 2.6e-53
HKALJCNE_02041 1.7e-07
HKALJCNE_02043 1.7e-50
HKALJCNE_02044 1.4e-47
HKALJCNE_02045 1.4e-249 ywqJ S Pre-toxin TG
HKALJCNE_02046 1.3e-38 ywqI S Family of unknown function (DUF5344)
HKALJCNE_02047 3.3e-15 S Domain of unknown function (DUF5082)
HKALJCNE_02048 1.4e-152 ywqG S Domain of unknown function (DUF1963)
HKALJCNE_02049 5.2e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKALJCNE_02050 2.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HKALJCNE_02051 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HKALJCNE_02052 2e-116 ywqC M biosynthesis protein
HKALJCNE_02053 1.2e-17
HKALJCNE_02054 5.6e-305 ywqB S SWIM zinc finger
HKALJCNE_02055 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKALJCNE_02056 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HKALJCNE_02057 3.4e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
HKALJCNE_02058 3.7e-57 ssbB L Single-stranded DNA-binding protein
HKALJCNE_02059 1.3e-66 ywpG
HKALJCNE_02060 1.1e-66 ywpF S YwpF-like protein
HKALJCNE_02061 8.7e-84 srtA 3.4.22.70 M Sortase family
HKALJCNE_02062 0.0 M1-568 M cell wall anchor domain
HKALJCNE_02063 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
HKALJCNE_02064 0.0 ywpD T PhoQ Sensor
HKALJCNE_02065 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKALJCNE_02066 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKALJCNE_02067 4.4e-197 S aspartate phosphatase
HKALJCNE_02068 2.6e-141 flhP N flagellar basal body
HKALJCNE_02069 1.5e-125 flhO N flagellar basal body
HKALJCNE_02070 3.5e-180 mbl D Rod shape-determining protein
HKALJCNE_02071 3e-44 spoIIID K Stage III sporulation protein D
HKALJCNE_02072 2.1e-70 ywoH K COG1846 Transcriptional regulators
HKALJCNE_02073 7.8e-211 ywoG EGP Major facilitator Superfamily
HKALJCNE_02074 1.4e-230 ywoF P Right handed beta helix region
HKALJCNE_02075 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HKALJCNE_02076 9.8e-242 ywoD EGP Major facilitator superfamily
HKALJCNE_02077 4e-104 phzA Q Isochorismatase family
HKALJCNE_02078 2.2e-76
HKALJCNE_02079 4.3e-225 amt P Ammonium transporter
HKALJCNE_02080 1.6e-58 nrgB K Belongs to the P(II) protein family
HKALJCNE_02081 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HKALJCNE_02082 3.5e-73 ywnJ S VanZ like family
HKALJCNE_02083 2.6e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HKALJCNE_02084 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HKALJCNE_02085 2.7e-14 ywnC S Family of unknown function (DUF5362)
HKALJCNE_02086 2.2e-70 ywnF S Family of unknown function (DUF5392)
HKALJCNE_02087 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKALJCNE_02088 2.6e-143 mta K transcriptional
HKALJCNE_02089 2.6e-59 ywnC S Family of unknown function (DUF5362)
HKALJCNE_02090 2e-112 ywnB S NAD(P)H-binding
HKALJCNE_02091 1.7e-64 ywnA K Transcriptional regulator
HKALJCNE_02092 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HKALJCNE_02093 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HKALJCNE_02094 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HKALJCNE_02095 3.6e-17 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HKALJCNE_02096 5.4e-08 urtA E Receptor family ligand binding region
HKALJCNE_02097 3.8e-11 csbD K CsbD-like
HKALJCNE_02098 3e-84 ywmF S Peptidase M50
HKALJCNE_02099 4.6e-104 S response regulator aspartate phosphatase
HKALJCNE_02100 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HKALJCNE_02101 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HKALJCNE_02103 2.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HKALJCNE_02104 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HKALJCNE_02105 1e-174 spoIID D Stage II sporulation protein D
HKALJCNE_02106 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKALJCNE_02107 2.4e-133 ywmB S TATA-box binding
HKALJCNE_02108 1.3e-32 ywzB S membrane
HKALJCNE_02109 4.3e-88 ywmA
HKALJCNE_02110 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKALJCNE_02111 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKALJCNE_02112 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKALJCNE_02113 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKALJCNE_02114 1.2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKALJCNE_02115 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKALJCNE_02116 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKALJCNE_02117 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HKALJCNE_02118 2.5e-62 atpI S ATP synthase
HKALJCNE_02119 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKALJCNE_02120 1.7e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKALJCNE_02121 7.2e-95 ywlG S Belongs to the UPF0340 family
HKALJCNE_02122 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HKALJCNE_02123 6.2e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKALJCNE_02124 1.7e-91 mntP P Probably functions as a manganese efflux pump
HKALJCNE_02125 1.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKALJCNE_02126 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HKALJCNE_02127 3e-111 spoIIR S stage II sporulation protein R
HKALJCNE_02128 3.7e-55 ywlA S Uncharacterised protein family (UPF0715)
HKALJCNE_02130 1.2e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKALJCNE_02131 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKALJCNE_02132 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKALJCNE_02133 6.4e-75 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HKALJCNE_02134 8.6e-160 ywkB S Membrane transport protein
HKALJCNE_02135 0.0 sfcA 1.1.1.38 C malic enzyme
HKALJCNE_02136 7e-104 tdk 2.7.1.21 F thymidine kinase
HKALJCNE_02137 1.1e-32 rpmE J Binds the 23S rRNA
HKALJCNE_02138 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKALJCNE_02139 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HKALJCNE_02140 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKALJCNE_02141 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKALJCNE_02142 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HKALJCNE_02143 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HKALJCNE_02144 1.8e-90 ywjG S Domain of unknown function (DUF2529)
HKALJCNE_02145 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKALJCNE_02146 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKALJCNE_02147 4.4e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HKALJCNE_02148 0.0 fadF C COG0247 Fe-S oxidoreductase
HKALJCNE_02149 1.1e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HKALJCNE_02150 4.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HKALJCNE_02151 2.7e-42 ywjC
HKALJCNE_02152 1.1e-95 ywjB H RibD C-terminal domain
HKALJCNE_02153 0.0 ywjA V ABC transporter
HKALJCNE_02154 5.5e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKALJCNE_02155 4.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
HKALJCNE_02156 5.2e-93 narJ 1.7.5.1 C nitrate reductase
HKALJCNE_02157 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
HKALJCNE_02158 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKALJCNE_02159 7e-86 arfM T cyclic nucleotide binding
HKALJCNE_02160 2.2e-136 ywiC S YwiC-like protein
HKALJCNE_02161 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HKALJCNE_02162 3e-213 narK P COG2223 Nitrate nitrite transporter
HKALJCNE_02163 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKALJCNE_02164 4.7e-73 ywiB S protein conserved in bacteria
HKALJCNE_02165 1e-07 S Bacteriocin subtilosin A
HKALJCNE_02166 1.1e-266 C Fe-S oxidoreductases
HKALJCNE_02168 1.3e-131 cbiO V ABC transporter
HKALJCNE_02169 3.6e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HKALJCNE_02170 1e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
HKALJCNE_02171 5e-248 L Peptidase, M16
HKALJCNE_02173 1.4e-243 ywhL CO amine dehydrogenase activity
HKALJCNE_02174 1.7e-190 ywhK CO amine dehydrogenase activity
HKALJCNE_02175 6.8e-79 S aspartate phosphatase
HKALJCNE_02177 1.4e-17 ywhH S Aminoacyl-tRNA editing domain
HKALJCNE_02178 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HKALJCNE_02179 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HKALJCNE_02180 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKALJCNE_02181 3.6e-49
HKALJCNE_02182 5.2e-95 ywhD S YwhD family
HKALJCNE_02183 5.1e-119 ywhC S Peptidase family M50
HKALJCNE_02184 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HKALJCNE_02185 3.6e-70 ywhA K Transcriptional regulator
HKALJCNE_02186 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKALJCNE_02187 1.6e-13
HKALJCNE_02188 1.5e-248 M nucleic acid phosphodiester bond hydrolysis
HKALJCNE_02189 1.1e-30
HKALJCNE_02190 5.2e-18
HKALJCNE_02192 2.7e-211 yjcL S Protein of unknown function (DUF819)
HKALJCNE_02193 5.9e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
HKALJCNE_02194 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKALJCNE_02195 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKALJCNE_02196 2.9e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
HKALJCNE_02197 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HKALJCNE_02198 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKALJCNE_02199 4.9e-38
HKALJCNE_02200 0.0 yjcD 3.6.4.12 L DNA helicase
HKALJCNE_02201 2.9e-38 spoVIF S Stage VI sporulation protein F
HKALJCNE_02204 4.3e-56 yjcA S Protein of unknown function (DUF1360)
HKALJCNE_02205 7.2e-49 cotV S Spore Coat Protein X and V domain
HKALJCNE_02206 7.4e-23 cotW
HKALJCNE_02207 1.2e-67 cotX S Spore Coat Protein X and V domain
HKALJCNE_02208 3.4e-96 cotY S Spore coat protein Z
HKALJCNE_02209 5.2e-83 cotZ S Spore coat protein
HKALJCNE_02210 6.5e-53 yjbX S Spore coat protein
HKALJCNE_02211 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HKALJCNE_02212 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKALJCNE_02213 3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKALJCNE_02214 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HKALJCNE_02215 6.7e-30 thiS H thiamine diphosphate biosynthetic process
HKALJCNE_02216 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
HKALJCNE_02217 1.3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HKALJCNE_02218 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKALJCNE_02219 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKALJCNE_02220 9.6e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HKALJCNE_02221 1.4e-156 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKALJCNE_02222 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKALJCNE_02223 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HKALJCNE_02224 1.6e-61 yjbL S Belongs to the UPF0738 family
HKALJCNE_02225 2.1e-100 yjbK S protein conserved in bacteria
HKALJCNE_02226 5.5e-82 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKALJCNE_02227 3.7e-72 yjbI S Bacterial-like globin
HKALJCNE_02228 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKALJCNE_02230 1.8e-20
HKALJCNE_02231 0.0 pepF E oligoendopeptidase F
HKALJCNE_02232 4e-220 yjbF S Competence protein
HKALJCNE_02233 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKALJCNE_02234 6e-112 yjbE P Integral membrane protein TerC family
HKALJCNE_02235 1.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKALJCNE_02236 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKALJCNE_02237 6.3e-205 yjbB EGP Major Facilitator Superfamily
HKALJCNE_02238 1.2e-171 oppF E Belongs to the ABC transporter superfamily
HKALJCNE_02239 3.4e-197 oppD P Belongs to the ABC transporter superfamily
HKALJCNE_02240 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKALJCNE_02241 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKALJCNE_02242 0.0 oppA E ABC transporter substrate-binding protein
HKALJCNE_02243 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HKALJCNE_02244 5e-147 yjbA S Belongs to the UPF0736 family
HKALJCNE_02245 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKALJCNE_02246 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKALJCNE_02247 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HKALJCNE_02248 1.2e-185 appF E Belongs to the ABC transporter superfamily
HKALJCNE_02249 8.8e-184 appD P Belongs to the ABC transporter superfamily
HKALJCNE_02250 3.3e-149 yjaZ O Zn-dependent protease
HKALJCNE_02251 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKALJCNE_02252 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKALJCNE_02253 5e-21 yjzB
HKALJCNE_02254 1.6e-25 comZ S ComZ
HKALJCNE_02255 2.5e-183 med S Transcriptional activator protein med
HKALJCNE_02256 5.8e-100 yjaV
HKALJCNE_02257 2.4e-141 yjaU I carboxylic ester hydrolase activity
HKALJCNE_02258 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HKALJCNE_02259 9.5e-28 yjzC S YjzC-like protein
HKALJCNE_02260 4.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKALJCNE_02261 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HKALJCNE_02262 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKALJCNE_02263 3.7e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HKALJCNE_02264 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HKALJCNE_02265 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKALJCNE_02266 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKALJCNE_02267 1.7e-88 norB G Major Facilitator Superfamily
HKALJCNE_02268 2.2e-268 yitY C D-arabinono-1,4-lactone oxidase
HKALJCNE_02269 1.5e-22 pilT S Proteolipid membrane potential modulator
HKALJCNE_02270 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HKALJCNE_02271 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HKALJCNE_02272 3.9e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HKALJCNE_02273 1.2e-17 S Protein of unknown function (DUF3813)
HKALJCNE_02274 3.8e-73 ipi S Intracellular proteinase inhibitor
HKALJCNE_02275 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HKALJCNE_02276 2.5e-158 yitS S protein conserved in bacteria
HKALJCNE_02277 4.2e-308 nprB 3.4.24.28 E Peptidase M4
HKALJCNE_02278 1.4e-44 yitR S Domain of unknown function (DUF3784)
HKALJCNE_02279 3.6e-92
HKALJCNE_02280 1.5e-58 K Transcriptional regulator PadR-like family
HKALJCNE_02281 1.5e-97 S Sporulation delaying protein SdpA
HKALJCNE_02282 4.7e-171
HKALJCNE_02283 8.5e-94
HKALJCNE_02284 6.9e-161 cvfB S protein conserved in bacteria
HKALJCNE_02285 4.3e-54 yajQ S Belongs to the UPF0234 family
HKALJCNE_02286 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKALJCNE_02287 1e-70 yjcF S Acetyltransferase (GNAT) domain
HKALJCNE_02288 1.8e-153 yitH K Acetyltransferase (GNAT) domain
HKALJCNE_02289 2e-228 yitG EGP Major facilitator Superfamily
HKALJCNE_02290 6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKALJCNE_02291 9.5e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKALJCNE_02292 1.6e-140 yitD 4.4.1.19 S synthase
HKALJCNE_02293 2e-118 comB 3.1.3.71 H Belongs to the ComB family
HKALJCNE_02294 5.1e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HKALJCNE_02295 1.3e-229 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HKALJCNE_02296 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HKALJCNE_02297 4.5e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKALJCNE_02298 4e-36 mcbG S Pentapeptide repeats (9 copies)
HKALJCNE_02299 1.2e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKALJCNE_02300 2e-106 argO S Lysine exporter protein LysE YggA
HKALJCNE_02301 1.5e-91 yisT S DinB family
HKALJCNE_02302 6.3e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HKALJCNE_02303 2.4e-184 purR K helix_turn _helix lactose operon repressor
HKALJCNE_02304 1.2e-160 yisR K Transcriptional regulator
HKALJCNE_02305 1.5e-242 yisQ V Mate efflux family protein
HKALJCNE_02306 4.1e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HKALJCNE_02307 4.7e-88 yizA S Damage-inducible protein DinB
HKALJCNE_02308 0.0 asnO 6.3.5.4 E Asparagine synthase
HKALJCNE_02309 1.5e-100 yisN S Protein of unknown function (DUF2777)
HKALJCNE_02310 0.0 wprA O Belongs to the peptidase S8 family
HKALJCNE_02311 3e-57 yisL S UPF0344 protein
HKALJCNE_02312 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HKALJCNE_02313 3.1e-175 cotH M Spore Coat
HKALJCNE_02314 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HKALJCNE_02315 1.9e-33 gerPA S Spore germination protein
HKALJCNE_02316 4e-34 gerPB S cell differentiation
HKALJCNE_02317 7e-54 gerPC S Spore germination protein
HKALJCNE_02318 3.1e-23 gerPD S Spore germination protein
HKALJCNE_02319 3.1e-63 gerPE S Spore germination protein GerPE
HKALJCNE_02320 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HKALJCNE_02321 3e-50 yisB V COG1403 Restriction endonuclease
HKALJCNE_02322 0.0 sbcC L COG0419 ATPase involved in DNA repair
HKALJCNE_02323 6.3e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKALJCNE_02324 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKALJCNE_02325 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HKALJCNE_02326 4.9e-78 yhjR S Rubrerythrin
HKALJCNE_02327 0.0 S Sugar transport-related sRNA regulator N-term
HKALJCNE_02328 2.1e-208 EGP Transmembrane secretion effector
HKALJCNE_02329 1.2e-200 abrB S membrane
HKALJCNE_02330 6.5e-187 yhjM 5.1.1.1 K Transcriptional regulator
HKALJCNE_02331 9.2e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HKALJCNE_02332 9e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HKALJCNE_02333 4.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HKALJCNE_02334 1e-213 glcP G Major Facilitator Superfamily
HKALJCNE_02336 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_02337 6.6e-284 yhjG CH FAD binding domain
HKALJCNE_02338 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HKALJCNE_02339 9.1e-110 yhjE S SNARE associated Golgi protein
HKALJCNE_02340 1.1e-59 yhjD
HKALJCNE_02341 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HKALJCNE_02342 4.9e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKALJCNE_02343 1.2e-39 yhjA S Excalibur calcium-binding domain
HKALJCNE_02344 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HKALJCNE_02345 9.3e-109 comK K Competence transcription factor
HKALJCNE_02346 1.3e-32 yhzC S IDEAL
HKALJCNE_02347 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_02348 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HKALJCNE_02349 4.9e-182 hemAT NT chemotaxis protein
HKALJCNE_02350 5e-91 bioY S BioY family
HKALJCNE_02351 5.8e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HKALJCNE_02352 1.2e-197 vraB 2.3.1.9 I Belongs to the thiolase family
HKALJCNE_02353 1.2e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HKALJCNE_02354 1.8e-157 yfmC M Periplasmic binding protein
HKALJCNE_02355 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HKALJCNE_02356 1.1e-77 VY92_01935 K acetyltransferase
HKALJCNE_02357 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HKALJCNE_02358 6.9e-237 yhfN 3.4.24.84 O Peptidase M48
HKALJCNE_02359 1.9e-65 yhfM
HKALJCNE_02360 4.5e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HKALJCNE_02361 1.2e-109 yhfK GM NmrA-like family
HKALJCNE_02362 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HKALJCNE_02363 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HKALJCNE_02364 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKALJCNE_02365 3.7e-72 3.4.13.21 S ASCH
HKALJCNE_02366 5.1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HKALJCNE_02367 1.7e-134 yhfC S Putative membrane peptidase family (DUF2324)
HKALJCNE_02368 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKALJCNE_02369 1.1e-213 yhgE S YhgE Pip N-terminal domain protein
HKALJCNE_02370 5.4e-101 yhgD K Transcriptional regulator
HKALJCNE_02371 2e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HKALJCNE_02372 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HKALJCNE_02373 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HKALJCNE_02374 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKALJCNE_02375 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HKALJCNE_02376 4.1e-28 1.15.1.2 C Rubrerythrin
HKALJCNE_02377 3.8e-241 yhfA C membrane
HKALJCNE_02378 1.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HKALJCNE_02379 4.5e-113 ecsC S EcsC protein family
HKALJCNE_02380 5.4e-215 ecsB U ABC transporter
HKALJCNE_02381 4.6e-137 ecsA V transporter (ATP-binding protein)
HKALJCNE_02382 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HKALJCNE_02383 1.9e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKALJCNE_02384 3.6e-80 trpP S Tryptophan transporter TrpP
HKALJCNE_02385 5.4e-21
HKALJCNE_02386 8.2e-39 yhaH S YtxH-like protein
HKALJCNE_02387 1e-113 hpr K Negative regulator of protease production and sporulation
HKALJCNE_02388 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HKALJCNE_02389 8.7e-90 yhaK S Putative zincin peptidase
HKALJCNE_02390 3e-111 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKALJCNE_02391 3.6e-67 S Domain of unknown function, YrpD
HKALJCNE_02393 3.3e-163 S Thymidylate synthase
HKALJCNE_02396 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HKALJCNE_02397 2e-82 yncE S Protein of unknown function (DUF2691)
HKALJCNE_02399 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKALJCNE_02400 6.1e-255 iolT EGP Major facilitator Superfamily
HKALJCNE_02401 8.2e-39 yokF 3.1.31.1 L RNA catabolic process
HKALJCNE_02402 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HKALJCNE_02403 4.4e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HKALJCNE_02404 2.8e-213 xylR GK ROK family
HKALJCNE_02405 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HKALJCNE_02406 1.9e-253 xynT G MFS/sugar transport protein
HKALJCNE_02407 2.3e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HKALJCNE_02409 1.3e-56 ynaF
HKALJCNE_02410 8.1e-122 ynaE S Domain of unknown function (DUF3885)
HKALJCNE_02411 3.6e-96 ynaD J Acetyltransferase (GNAT) domain
HKALJCNE_02412 1.7e-93 G SMI1-KNR4 cell-wall
HKALJCNE_02413 2.1e-36
HKALJCNE_02414 8.5e-124
HKALJCNE_02415 5.6e-30
HKALJCNE_02416 3.8e-10
HKALJCNE_02417 7e-261 glnA 6.3.1.2 E glutamine synthetase
HKALJCNE_02418 1.1e-68 glnR K transcriptional
HKALJCNE_02419 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HKALJCNE_02420 6.7e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKALJCNE_02421 1.7e-176 spoVK O stage V sporulation protein K
HKALJCNE_02422 1.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKALJCNE_02423 2e-109 ymaB
HKALJCNE_02424 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKALJCNE_02425 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKALJCNE_02426 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HKALJCNE_02427 4.5e-22 ymzA
HKALJCNE_02428 8.2e-23
HKALJCNE_02429 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HKALJCNE_02430 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKALJCNE_02431 2.1e-46 ymaF S YmaF family
HKALJCNE_02433 5.4e-50 ebrA P Small Multidrug Resistance protein
HKALJCNE_02434 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HKALJCNE_02435 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
HKALJCNE_02436 1.3e-125 ymaC S Replication protein
HKALJCNE_02437 1.9e-07 K Transcriptional regulator
HKALJCNE_02438 6.6e-251 aprX O Belongs to the peptidase S8 family
HKALJCNE_02439 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
HKALJCNE_02440 4.9e-60 ymzB
HKALJCNE_02441 2e-230 cypA C Cytochrome P450
HKALJCNE_02442 0.0 pks13 HQ Beta-ketoacyl synthase
HKALJCNE_02443 0.0 dhbF IQ polyketide synthase
HKALJCNE_02444 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HKALJCNE_02445 0.0 pfaA Q Polyketide synthase of type I
HKALJCNE_02446 0.0 rhiB IQ polyketide synthase
HKALJCNE_02447 1e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HKALJCNE_02448 2.7e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
HKALJCNE_02449 3.3e-244 pksG 2.3.3.10 I synthase
HKALJCNE_02450 6.6e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKALJCNE_02451 1.4e-37 acpK IQ Phosphopantetheine attachment site
HKALJCNE_02452 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKALJCNE_02453 6.9e-181 pksD Q Acyl transferase domain
HKALJCNE_02455 6.4e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKALJCNE_02456 3.7e-125 pksB 3.1.2.6 S Polyketide biosynthesis
HKALJCNE_02457 7.6e-109 pksA K Transcriptional regulator
HKALJCNE_02458 1e-96 ymcC S Membrane
HKALJCNE_02460 2e-69 S Regulatory protein YrvL
HKALJCNE_02461 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKALJCNE_02462 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKALJCNE_02463 2.2e-88 cotE S Spore coat protein
HKALJCNE_02464 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HKALJCNE_02465 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKALJCNE_02466 4.7e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKALJCNE_02467 3.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HKALJCNE_02468 1.2e-36 spoVS S Stage V sporulation protein S
HKALJCNE_02469 1.9e-152 ymdB S protein conserved in bacteria
HKALJCNE_02470 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HKALJCNE_02471 9.1e-212 pbpX V Beta-lactamase
HKALJCNE_02472 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKALJCNE_02473 2.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
HKALJCNE_02474 5.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKALJCNE_02475 1.9e-124 ymfM S protein conserved in bacteria
HKALJCNE_02476 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HKALJCNE_02477 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HKALJCNE_02478 1.9e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HKALJCNE_02479 1.4e-242 ymfH S zinc protease
HKALJCNE_02480 2.7e-233 ymfF S Peptidase M16
HKALJCNE_02481 3.8e-205 ymfD EGP Major facilitator Superfamily
HKALJCNE_02482 1.4e-133 ymfC K Transcriptional regulator
HKALJCNE_02483 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKALJCNE_02484 4.4e-32 S YlzJ-like protein
HKALJCNE_02485 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HKALJCNE_02486 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKALJCNE_02487 8.9e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKALJCNE_02488 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HKALJCNE_02489 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKALJCNE_02490 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HKALJCNE_02491 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HKALJCNE_02492 2.6e-42 ymxH S YlmC YmxH family
HKALJCNE_02493 2.2e-232 pepR S Belongs to the peptidase M16 family
HKALJCNE_02494 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HKALJCNE_02495 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKALJCNE_02496 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKALJCNE_02497 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKALJCNE_02498 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKALJCNE_02499 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKALJCNE_02500 3.9e-44 ylxP S protein conserved in bacteria
HKALJCNE_02501 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKALJCNE_02502 3.1e-47 ylxQ J ribosomal protein
HKALJCNE_02503 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HKALJCNE_02504 1.1e-203 nusA K Participates in both transcription termination and antitermination
HKALJCNE_02505 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HKALJCNE_02506 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKALJCNE_02507 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKALJCNE_02508 7.7e-233 rasP M zinc metalloprotease
HKALJCNE_02509 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKALJCNE_02510 4.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HKALJCNE_02511 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKALJCNE_02512 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKALJCNE_02513 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKALJCNE_02514 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKALJCNE_02515 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HKALJCNE_02516 4.8e-77 ylxL
HKALJCNE_02517 7.4e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKALJCNE_02518 1.9e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HKALJCNE_02519 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HKALJCNE_02520 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HKALJCNE_02521 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HKALJCNE_02522 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HKALJCNE_02523 1e-57 flhG D Belongs to the ParA family
HKALJCNE_02524 7e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HKALJCNE_02525 1.7e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
HKALJCNE_02526 5.1e-246 yoeA V MATE efflux family protein
HKALJCNE_02527 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HKALJCNE_02529 2.2e-96 L Integrase
HKALJCNE_02530 3e-34 yoeD G Helix-turn-helix domain
HKALJCNE_02531 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HKALJCNE_02532 1.1e-155 gltR1 K Transcriptional regulator
HKALJCNE_02533 2.3e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKALJCNE_02534 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HKALJCNE_02535 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HKALJCNE_02536 7.8e-155 gltC K Transcriptional regulator
HKALJCNE_02537 1.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKALJCNE_02538 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKALJCNE_02539 2.5e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HKALJCNE_02540 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_02541 9.2e-39 yoxC S Bacterial protein of unknown function (DUF948)
HKALJCNE_02542 8e-132 yoxB
HKALJCNE_02543 2.9e-96 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKALJCNE_02544 4e-234 yoaB EGP Major facilitator Superfamily
HKALJCNE_02545 2e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HKALJCNE_02546 1.3e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKALJCNE_02547 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKALJCNE_02548 1.5e-31 yoaF
HKALJCNE_02549 1.9e-171 iolT EGP Major facilitator Superfamily
HKALJCNE_02550 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
HKALJCNE_02551 1.4e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
HKALJCNE_02552 3.3e-90 purR K Transcriptional regulator
HKALJCNE_02553 2.2e-07
HKALJCNE_02554 7e-14
HKALJCNE_02555 7.7e-35 S Protein of unknown function (DUF4025)
HKALJCNE_02556 9.4e-178 mcpU NT methyl-accepting chemotaxis protein
HKALJCNE_02557 1.5e-277 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HKALJCNE_02558 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HKALJCNE_02559 2.3e-111 yoaK S Membrane
HKALJCNE_02560 7.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HKALJCNE_02561 4.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HKALJCNE_02564 1.3e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
HKALJCNE_02566 6.1e-18 yoaP 3.1.3.18 K YoaP-like
HKALJCNE_02567 2.5e-86
HKALJCNE_02568 7.1e-172 yoaR V vancomycin resistance protein
HKALJCNE_02569 7.3e-75 yoaS S Protein of unknown function (DUF2975)
HKALJCNE_02570 6e-30 yozG K Transcriptional regulator
HKALJCNE_02571 5.7e-149 yoaT S Protein of unknown function (DUF817)
HKALJCNE_02572 3.3e-158 yoaU K LysR substrate binding domain
HKALJCNE_02573 1.9e-158 yijE EG EamA-like transporter family
HKALJCNE_02574 2e-76 yoaW
HKALJCNE_02575 7.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HKALJCNE_02576 2.4e-167 bla 3.5.2.6 V beta-lactamase
HKALJCNE_02579 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HKALJCNE_02580 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_02581 0.0 vicK 2.7.13.3 T Histidine kinase
HKALJCNE_02582 1.5e-258 yycH S protein conserved in bacteria
HKALJCNE_02583 6.2e-154 yycI S protein conserved in bacteria
HKALJCNE_02584 5.7e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HKALJCNE_02585 3.2e-220 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKALJCNE_02586 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HKALJCNE_02587 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HKALJCNE_02588 4.8e-260 rocE E amino acid
HKALJCNE_02589 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HKALJCNE_02591 1.5e-187 S aspartate phosphatase
HKALJCNE_02592 2.9e-84 yycN 2.3.1.128 K Acetyltransferase
HKALJCNE_02593 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKALJCNE_02594 1.9e-209 yycP
HKALJCNE_02595 1.1e-29 yycQ S Protein of unknown function (DUF2651)
HKALJCNE_02597 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKALJCNE_02598 4.1e-66
HKALJCNE_02599 1.1e-09 S YyzF-like protein
HKALJCNE_02600 9.8e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKALJCNE_02601 6.2e-180 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
HKALJCNE_02602 1.6e-165 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HKALJCNE_02603 1.6e-267 S Z1 domain
HKALJCNE_02604 1.7e-97 S Putative PD-(D/E)XK family member, (DUF4420)
HKALJCNE_02605 3.6e-231 S AIPR protein
HKALJCNE_02606 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HKALJCNE_02607 1.3e-108 prrC P ABC transporter
HKALJCNE_02608 3e-117 S ABC-2 family transporter protein
HKALJCNE_02609 2.5e-124 yydK K Transcriptional regulator
HKALJCNE_02610 3.1e-19 bglF G phosphotransferase system
HKALJCNE_02611 4.1e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKALJCNE_02612 7.3e-189 wgaE S Polysaccharide pyruvyl transferase
HKALJCNE_02613 1.2e-285 ahpF O Alkyl hydroperoxide reductase
HKALJCNE_02614 6.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HKALJCNE_02615 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HKALJCNE_02616 6.1e-76 xkdM S Phage tail tube protein
HKALJCNE_02617 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HKALJCNE_02618 1.9e-77 xkdJ
HKALJCNE_02619 1.9e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
HKALJCNE_02620 3.3e-64 yqbH S Domain of unknown function (DUF3599)
HKALJCNE_02621 1.5e-62 yqbG S Protein of unknown function (DUF3199)
HKALJCNE_02622 5.8e-169 xkdG S Phage capsid family
HKALJCNE_02623 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HKALJCNE_02624 1.6e-285 yqbA S portal protein
HKALJCNE_02625 1.2e-252 xtmB S phage terminase, large subunit
HKALJCNE_02626 1.2e-138 xtmA L phage terminase small subunit
HKALJCNE_02627 2.4e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HKALJCNE_02628 1.8e-09 yqaO S Phage-like element PBSX protein XtrA
HKALJCNE_02632 6.4e-119 xkdC L Bacterial dnaA protein
HKALJCNE_02633 6.6e-156 xkdB K sequence-specific DNA binding
HKALJCNE_02635 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HKALJCNE_02636 1e-110 xkdA E IrrE N-terminal-like domain
HKALJCNE_02637 4.4e-160 ydbD P Catalase
HKALJCNE_02638 6.3e-108 yjqB S Pfam:DUF867
HKALJCNE_02639 1.4e-60 yjqA S Bacterial PH domain
HKALJCNE_02640 1.9e-151 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HKALJCNE_02641 6.3e-41 S YCII-related domain
HKALJCNE_02643 1e-212 S response regulator aspartate phosphatase
HKALJCNE_02644 1.5e-244 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HKALJCNE_02645 8e-79 yjoA S DinB family
HKALJCNE_02646 7.4e-130 MA20_18170 S membrane transporter protein
HKALJCNE_02647 2.5e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HKALJCNE_02648 3.8e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HKALJCNE_02649 5.2e-184 exuR K transcriptional
HKALJCNE_02650 8.3e-227 exuT G Sugar (and other) transporter
HKALJCNE_02651 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_02652 6.4e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HKALJCNE_02653 9.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HKALJCNE_02654 4.2e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HKALJCNE_02655 2.7e-247 yjmB G symporter YjmB
HKALJCNE_02656 3.5e-279 uxaC 5.3.1.12 G glucuronate isomerase
HKALJCNE_02657 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HKALJCNE_02658 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HKALJCNE_02659 7.5e-91 yjlB S Cupin domain
HKALJCNE_02660 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
HKALJCNE_02661 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HKALJCNE_02662 1.9e-122 ybbM S transport system, permease component
HKALJCNE_02663 3e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKALJCNE_02664 8.2e-30
HKALJCNE_02665 5e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKALJCNE_02666 1e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HKALJCNE_02668 2.4e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HKALJCNE_02669 8.7e-07 S Domain of unknown function (DUF4352)
HKALJCNE_02670 5.7e-95 yjgD S Protein of unknown function (DUF1641)
HKALJCNE_02671 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HKALJCNE_02672 2e-103 yjgB S Domain of unknown function (DUF4309)
HKALJCNE_02673 2.7e-45 T PhoQ Sensor
HKALJCNE_02674 1.2e-129 yjfC O Predicted Zn-dependent protease (DUF2268)
HKALJCNE_02675 2.3e-27 yjfC O Predicted Zn-dependent protease (DUF2268)
HKALJCNE_02676 2.3e-20 yjfB S Putative motility protein
HKALJCNE_02677 5.5e-83 S Protein of unknown function (DUF2690)
HKALJCNE_02678 4.6e-263 xynD 3.5.1.104 G Polysaccharide deacetylase
HKALJCNE_02680 3.1e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKALJCNE_02681 3.5e-52 yjdJ S Domain of unknown function (DUF4306)
HKALJCNE_02682 4.2e-29 S Domain of unknown function (DUF4177)
HKALJCNE_02683 3e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKALJCNE_02685 1.8e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HKALJCNE_02686 2.7e-49 yjdF S Protein of unknown function (DUF2992)
HKALJCNE_02687 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKALJCNE_02688 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HKALJCNE_02689 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HKALJCNE_02690 2.3e-45 yjcN
HKALJCNE_02691 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
HKALJCNE_02692 1.9e-166 S response regulator aspartate phosphatase
HKALJCNE_02695 1e-86 spsL 5.1.3.13 M Spore Coat
HKALJCNE_02696 1.2e-77
HKALJCNE_02697 2.8e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKALJCNE_02698 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKALJCNE_02699 0.0 rocB E arginine degradation protein
HKALJCNE_02700 7.4e-250 lysP E amino acid
HKALJCNE_02701 1.5e-204 ywfA EGP Major facilitator Superfamily
HKALJCNE_02702 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HKALJCNE_02703 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HKALJCNE_02704 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_02705 1e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HKALJCNE_02706 2.5e-209 bacE EGP Major facilitator Superfamily
HKALJCNE_02707 1.6e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
HKALJCNE_02708 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
HKALJCNE_02709 1.1e-146 ywfI C May function as heme-dependent peroxidase
HKALJCNE_02710 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HKALJCNE_02711 1.1e-156 cysL K Transcriptional regulator
HKALJCNE_02712 2.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HKALJCNE_02713 3.1e-156 ywfM EG EamA-like transporter family
HKALJCNE_02714 5.1e-110 rsfA_1
HKALJCNE_02715 3.1e-36 ywzC S Belongs to the UPF0741 family
HKALJCNE_02716 1.9e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HKALJCNE_02717 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HKALJCNE_02718 1.4e-78 yffB K Transcriptional regulator
HKALJCNE_02719 1.5e-237 mmr U Major Facilitator Superfamily
HKALJCNE_02721 3.7e-162 yraN K Transcriptional regulator
HKALJCNE_02722 4.4e-223 yraO C Citrate transporter
HKALJCNE_02723 1.7e-187 yrpG C Aldo/keto reductase family
HKALJCNE_02724 1.3e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_02725 4.9e-110 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HKALJCNE_02727 8.7e-125 yrpD S Domain of unknown function, YrpD
HKALJCNE_02728 3.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKALJCNE_02729 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HKALJCNE_02730 5.1e-164 aadK G Streptomycin adenylyltransferase
HKALJCNE_02731 6.4e-90 yrdA S DinB family
HKALJCNE_02732 1.5e-54 S Protein of unknown function (DUF2568)
HKALJCNE_02733 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
HKALJCNE_02734 7.3e-228 cypA C Cytochrome P450
HKALJCNE_02735 0.0 copA 3.6.3.54 P P-type ATPase
HKALJCNE_02736 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKALJCNE_02737 1.6e-104 bdbD O Thioredoxin
HKALJCNE_02738 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HKALJCNE_02739 1.6e-106 yvgT S membrane
HKALJCNE_02741 0.0 helD 3.6.4.12 L DNA helicase
HKALJCNE_02742 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HKALJCNE_02743 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HKALJCNE_02744 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HKALJCNE_02745 5.4e-86 yvgO
HKALJCNE_02746 1.1e-155 yvgN S reductase
HKALJCNE_02747 1.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HKALJCNE_02748 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HKALJCNE_02749 5.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HKALJCNE_02750 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKALJCNE_02751 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HKALJCNE_02752 6.5e-16 S Small spore protein J (Spore_SspJ)
HKALJCNE_02753 1.4e-235 yvsH E Arginine ornithine antiporter
HKALJCNE_02754 5.3e-178 fhuD P ABC transporter
HKALJCNE_02755 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_02756 1.3e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_02757 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HKALJCNE_02758 4.8e-176 M Efflux transporter rnd family, mfp subunit
HKALJCNE_02759 7.9e-123 macB V ABC transporter, ATP-binding protein
HKALJCNE_02760 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HKALJCNE_02761 1.3e-64 yvrL S Regulatory protein YrvL
HKALJCNE_02762 1.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
HKALJCNE_02763 2.4e-19 S YvrJ protein family
HKALJCNE_02764 1.9e-98 yvrI K RNA polymerase
HKALJCNE_02765 9.4e-23
HKALJCNE_02766 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_02767 0.0 T PhoQ Sensor
HKALJCNE_02768 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HKALJCNE_02769 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_02770 5.8e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HKALJCNE_02771 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_02772 1.1e-237 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HKALJCNE_02773 2e-98 yvqK 2.5.1.17 S Adenosyltransferase
HKALJCNE_02774 4.5e-225 yvqJ EGP Major facilitator Superfamily
HKALJCNE_02775 2.8e-61 liaI S membrane
HKALJCNE_02776 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HKALJCNE_02777 3.7e-125 liaG S Putative adhesin
HKALJCNE_02778 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HKALJCNE_02779 3.5e-186 vraS 2.7.13.3 T Histidine kinase
HKALJCNE_02780 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKALJCNE_02781 1.1e-182 gerAC S Spore germination B3/ GerAC like, C-terminal
HKALJCNE_02782 3.2e-195 gerAB E Spore germination protein
HKALJCNE_02783 9.1e-246 gerAA EG Spore germination protein
HKALJCNE_02784 3.9e-24 S Protein of unknown function (DUF3970)
HKALJCNE_02785 1.6e-260 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKALJCNE_02786 4.3e-158 yuxN K Transcriptional regulator
HKALJCNE_02787 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HKALJCNE_02788 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_02789 6.2e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKALJCNE_02790 2.7e-79 dps P Ferritin-like domain
HKALJCNE_02791 1.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_02792 4.2e-301 pepF2 E COG1164 Oligoendopeptidase F
HKALJCNE_02793 2.5e-66 S YusW-like protein
HKALJCNE_02794 1e-153 yusV 3.6.3.34 HP ABC transporter
HKALJCNE_02795 5.6e-39 yusU S Protein of unknown function (DUF2573)
HKALJCNE_02796 5.7e-158 yusT K LysR substrate binding domain
HKALJCNE_02797 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_02798 4.6e-64 yusQ S Tautomerase enzyme
HKALJCNE_02799 1.2e-291 yusP P Major facilitator superfamily
HKALJCNE_02800 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HKALJCNE_02801 5.4e-53 yusN M Coat F domain
HKALJCNE_02802 5.1e-40
HKALJCNE_02803 1.2e-163 fadM E Proline dehydrogenase
HKALJCNE_02804 8.1e-09 S YuzL-like protein
HKALJCNE_02805 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HKALJCNE_02806 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HKALJCNE_02807 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HKALJCNE_02808 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HKALJCNE_02809 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HKALJCNE_02810 1.1e-39 yusG S Protein of unknown function (DUF2553)
HKALJCNE_02811 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HKALJCNE_02812 9.5e-55 traF CO Thioredoxin
HKALJCNE_02813 2.4e-56 yusD S SCP-2 sterol transfer family
HKALJCNE_02814 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HKALJCNE_02815 2.6e-150 pstS P Phosphate
HKALJCNE_02816 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HKALJCNE_02817 5.6e-231 yqgE EGP Major facilitator superfamily
HKALJCNE_02818 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HKALJCNE_02819 4e-73 yqgC S protein conserved in bacteria
HKALJCNE_02820 3.9e-131 yqgB S Protein of unknown function (DUF1189)
HKALJCNE_02821 5.8e-46 yqfZ M LysM domain
HKALJCNE_02822 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKALJCNE_02823 4.3e-62 yqfX S membrane
HKALJCNE_02824 4.6e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HKALJCNE_02825 7.1e-77 zur P Belongs to the Fur family
HKALJCNE_02826 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HKALJCNE_02827 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HKALJCNE_02828 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKALJCNE_02829 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKALJCNE_02830 2.1e-12 yqfQ S YqfQ-like protein
HKALJCNE_02831 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKALJCNE_02832 1.4e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKALJCNE_02833 2e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKALJCNE_02834 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HKALJCNE_02835 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKALJCNE_02836 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKALJCNE_02837 2.2e-87 yaiI S Belongs to the UPF0178 family
HKALJCNE_02838 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKALJCNE_02839 4.5e-112 ccpN K CBS domain
HKALJCNE_02840 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKALJCNE_02841 2.2e-173 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKALJCNE_02842 2.4e-144 recO L Involved in DNA repair and RecF pathway recombination
HKALJCNE_02843 8.4e-19 S YqzL-like protein
HKALJCNE_02844 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKALJCNE_02845 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKALJCNE_02846 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKALJCNE_02847 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKALJCNE_02848 0.0 yqfF S membrane-associated HD superfamily hydrolase
HKALJCNE_02850 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HKALJCNE_02851 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HKALJCNE_02852 2.7e-45 yqfC S sporulation protein YqfC
HKALJCNE_02853 1e-24 yqfB
HKALJCNE_02854 4.3e-122 yqfA S UPF0365 protein
HKALJCNE_02855 2.9e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HKALJCNE_02856 2.5e-61 yqeY S Yqey-like protein
HKALJCNE_02857 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKALJCNE_02858 4.1e-157 yqeW P COG1283 Na phosphate symporter
HKALJCNE_02859 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HKALJCNE_02860 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKALJCNE_02861 3e-173 prmA J Methylates ribosomal protein L11
HKALJCNE_02862 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKALJCNE_02863 0.0 dnaK O Heat shock 70 kDa protein
HKALJCNE_02864 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKALJCNE_02865 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKALJCNE_02866 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HKALJCNE_02867 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKALJCNE_02868 2.1e-52 yqxA S Protein of unknown function (DUF3679)
HKALJCNE_02869 1.5e-222 spoIIP M stage II sporulation protein P
HKALJCNE_02870 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HKALJCNE_02871 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HKALJCNE_02872 2.8e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
HKALJCNE_02873 4.1e-15 S YqzM-like protein
HKALJCNE_02874 0.0 comEC S Competence protein ComEC
HKALJCNE_02875 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HKALJCNE_02876 3.9e-97 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HKALJCNE_02877 5.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKALJCNE_02878 2.5e-138 yqeM Q Methyltransferase
HKALJCNE_02879 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKALJCNE_02880 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HKALJCNE_02881 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKALJCNE_02882 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HKALJCNE_02883 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKALJCNE_02884 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HKALJCNE_02885 5.3e-95 yqeG S hydrolase of the HAD superfamily
HKALJCNE_02887 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HKALJCNE_02888 8.9e-136 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKALJCNE_02889 3e-105 yqeD S SNARE associated Golgi protein
HKALJCNE_02890 1.4e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HKALJCNE_02891 1.7e-131 yqeB
HKALJCNE_02892 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HKALJCNE_02893 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKALJCNE_02894 6e-263 cisA2 L Recombinase
HKALJCNE_02895 0.0 levR K PTS system fructose IIA component
HKALJCNE_02896 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HKALJCNE_02897 1.1e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HKALJCNE_02898 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HKALJCNE_02899 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HKALJCNE_02900 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HKALJCNE_02901 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HKALJCNE_02902 2.5e-197 adhA 1.1.1.1 C alcohol dehydrogenase
HKALJCNE_02903 3.5e-18 yphJ 4.1.1.44 S peroxiredoxin activity
HKALJCNE_02904 4.3e-47 yraB K helix_turn_helix, mercury resistance
HKALJCNE_02905 1.1e-49 yraD M Spore coat protein
HKALJCNE_02906 4.9e-25 yraE
HKALJCNE_02907 8.8e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKALJCNE_02908 1.9e-62 yraF M Spore coat protein
HKALJCNE_02909 5.3e-37 yraG
HKALJCNE_02910 1.3e-66 E Glyoxalase-like domain
HKALJCNE_02911 2.4e-61 T sh3 domain protein
HKALJCNE_02912 4.9e-60 T sh3 domain protein
HKALJCNE_02913 2.6e-149 S Alpha beta hydrolase
HKALJCNE_02914 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKALJCNE_02915 5.3e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HKALJCNE_02916 6.5e-204 yraM S PrpF protein
HKALJCNE_02917 1e-33 V Beta-lactamase
HKALJCNE_02918 7e-56
HKALJCNE_02919 1.9e-201 ybcL EGP Major facilitator Superfamily
HKALJCNE_02920 5.1e-50 ybzH K Helix-turn-helix domain
HKALJCNE_02922 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HKALJCNE_02923 1.1e-46
HKALJCNE_02924 3.6e-91 can 4.2.1.1 P carbonic anhydrase
HKALJCNE_02925 0.0 ybcC S Belongs to the UPF0753 family
HKALJCNE_02926 3.8e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HKALJCNE_02927 9e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKALJCNE_02928 5.6e-115 adaA 3.2.2.21 K Transcriptional regulator
HKALJCNE_02929 9.3e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKALJCNE_02930 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKALJCNE_02931 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKALJCNE_02932 2.6e-224 ybbR S protein conserved in bacteria
HKALJCNE_02933 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKALJCNE_02934 6.5e-100 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HKALJCNE_02935 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_02936 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HKALJCNE_02937 7.9e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HKALJCNE_02938 4e-213 yaaH M Glycoside Hydrolase Family
HKALJCNE_02939 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HKALJCNE_02940 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKALJCNE_02941 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKALJCNE_02942 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKALJCNE_02943 5.1e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKALJCNE_02944 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HKALJCNE_02945 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HKALJCNE_02946 1.3e-215 yheC HJ YheC/D like ATP-grasp
HKALJCNE_02947 2.3e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HKALJCNE_02948 1.3e-36 yheE S Family of unknown function (DUF5342)
HKALJCNE_02949 6.3e-28 sspB S spore protein
HKALJCNE_02950 1.2e-109 yheG GM NAD(P)H-binding
HKALJCNE_02951 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKALJCNE_02952 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKALJCNE_02953 1.7e-83 nhaX T Belongs to the universal stress protein A family
HKALJCNE_02954 1.5e-229 nhaC C Na H antiporter
HKALJCNE_02955 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HKALJCNE_02956 6e-149 yheN G deacetylase
HKALJCNE_02957 7.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HKALJCNE_02958 9.9e-184 yhdY M Mechanosensitive ion channel
HKALJCNE_02960 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKALJCNE_02961 2.1e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKALJCNE_02962 3.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKALJCNE_02963 1.9e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HKALJCNE_02964 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
HKALJCNE_02965 4.1e-74 cueR K transcriptional
HKALJCNE_02966 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKALJCNE_02967 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKALJCNE_02968 1.5e-191 yhdN C Aldo keto reductase
HKALJCNE_02969 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_02970 3.3e-200 yhdL S Sigma factor regulator N-terminal
HKALJCNE_02971 8.1e-45 yhdK S Sigma-M inhibitor protein
HKALJCNE_02972 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKALJCNE_02973 2.1e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKALJCNE_02974 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKALJCNE_02975 3.4e-250 yhdG E amino acid
HKALJCNE_02976 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_02977 5.9e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HKALJCNE_02978 2.4e-161 citR K Transcriptional regulator
HKALJCNE_02979 5.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKALJCNE_02980 3.7e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HKALJCNE_02981 2.1e-276 ycgB S Stage V sporulation protein R
HKALJCNE_02982 4.3e-238 ygxB M Conserved TM helix
HKALJCNE_02983 1e-75 nsrR K Transcriptional regulator
HKALJCNE_02984 1.8e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKALJCNE_02985 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HKALJCNE_02986 1.2e-38 yhdB S YhdB-like protein
HKALJCNE_02987 3.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HKALJCNE_02988 1.7e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKALJCNE_02989 1.1e-113 yhcY 2.7.13.3 T Histidine kinase
HKALJCNE_02990 2.9e-82 yhcY 2.7.13.3 T Histidine kinase
HKALJCNE_02991 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HKALJCNE_02992 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HKALJCNE_02993 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKALJCNE_02994 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HKALJCNE_02995 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HKALJCNE_02996 7.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKALJCNE_02997 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKALJCNE_02998 1.3e-119 yhcW 5.4.2.6 S hydrolase
HKALJCNE_02999 9.9e-68 yhcV S COG0517 FOG CBS domain
HKALJCNE_03000 9.3e-68 yhcU S Family of unknown function (DUF5365)
HKALJCNE_03001 6.6e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKALJCNE_03002 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HKALJCNE_03003 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HKALJCNE_03004 1.5e-99 yhcQ M Spore coat protein
HKALJCNE_03005 9e-165 yhcP
HKALJCNE_03006 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKALJCNE_03007 4.1e-40 yhcM
HKALJCNE_03008 1.2e-49 K Transcriptional regulator PadR-like family
HKALJCNE_03009 3.4e-87 S Protein of unknown function (DUF2812)
HKALJCNE_03010 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKALJCNE_03011 4.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HKALJCNE_03012 1.1e-150 metQ M Belongs to the nlpA lipoprotein family
HKALJCNE_03013 1e-30 cspB K Cold-shock protein
HKALJCNE_03014 6.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKALJCNE_03015 1.9e-164 yhcH V ABC transporter, ATP-binding protein
HKALJCNE_03016 4e-122 yhcG V ABC transporter, ATP-binding protein
HKALJCNE_03017 6.6e-60 yhcF K Transcriptional regulator
HKALJCNE_03018 3.5e-55
HKALJCNE_03019 2.8e-37 yhcC
HKALJCNE_03020 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HKALJCNE_03021 3.1e-271 yhcA EGP Major facilitator Superfamily
HKALJCNE_03022 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HKALJCNE_03023 5.1e-60 yhbI K DNA-binding transcription factor activity
HKALJCNE_03024 7.2e-250 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_03025 4e-89 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_03026 3.6e-90 S nuclease activity
HKALJCNE_03027 1.4e-38 yxiC S Family of unknown function (DUF5344)
HKALJCNE_03028 2.3e-20 S Domain of unknown function (DUF5082)
HKALJCNE_03029 4.8e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HKALJCNE_03030 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HKALJCNE_03031 1.3e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
HKALJCNE_03032 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HKALJCNE_03033 1.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HKALJCNE_03034 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HKALJCNE_03035 3.4e-250 lysP E amino acid
HKALJCNE_03036 1e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HKALJCNE_03037 1.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKALJCNE_03038 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKALJCNE_03039 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKALJCNE_03040 4.4e-152 yxxB S Domain of Unknown Function (DUF1206)
HKALJCNE_03041 9.2e-198 eutH E Ethanolamine utilisation protein, EutH
HKALJCNE_03042 2.4e-248 yxeQ S MmgE/PrpD family
HKALJCNE_03043 3e-212 yxeP 3.5.1.47 E hydrolase activity
HKALJCNE_03044 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HKALJCNE_03045 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HKALJCNE_03046 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HKALJCNE_03047 4.7e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKALJCNE_03048 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKALJCNE_03049 6.1e-185 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HKALJCNE_03050 2.6e-149 yidA S hydrolases of the HAD superfamily
HKALJCNE_03053 1.3e-20 yxeE
HKALJCNE_03054 5.6e-16 yxeD
HKALJCNE_03055 8.5e-69
HKALJCNE_03056 5.6e-175 fhuD P ABC transporter
HKALJCNE_03057 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HKALJCNE_03058 0.0 yxdM V ABC transporter (permease)
HKALJCNE_03059 2.6e-138 yxdL V ABC transporter, ATP-binding protein
HKALJCNE_03060 2.6e-180 T PhoQ Sensor
HKALJCNE_03061 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_03062 3e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HKALJCNE_03063 1.1e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HKALJCNE_03064 2.5e-166 iolH G Xylose isomerase-like TIM barrel
HKALJCNE_03065 1e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HKALJCNE_03066 4.3e-234 iolF EGP Major facilitator Superfamily
HKALJCNE_03067 1.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKALJCNE_03068 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HKALJCNE_03069 5.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HKALJCNE_03070 7.8e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HKALJCNE_03071 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKALJCNE_03072 4.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HKALJCNE_03073 8.3e-176 iolS C Aldo keto reductase
HKALJCNE_03075 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HKALJCNE_03076 3.1e-243 csbC EGP Major facilitator Superfamily
HKALJCNE_03077 0.0 htpG O Molecular chaperone. Has ATPase activity
HKALJCNE_03079 1.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
HKALJCNE_03080 1.2e-208 yxbF K Bacterial regulatory proteins, tetR family
HKALJCNE_03081 4.9e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HKALJCNE_03082 2.2e-31 yxaI S membrane protein domain
HKALJCNE_03083 1.1e-90 S PQQ-like domain
HKALJCNE_03084 1.8e-61 S Family of unknown function (DUF5391)
HKALJCNE_03085 1.4e-75 yxaI S membrane protein domain
HKALJCNE_03086 1.1e-223 P Protein of unknown function (DUF418)
HKALJCNE_03087 2.4e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
HKALJCNE_03088 7.1e-101 yxaF K Transcriptional regulator
HKALJCNE_03089 9.5e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKALJCNE_03090 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_03091 5.2e-50 S LrgA family
HKALJCNE_03092 1.3e-117 yxaC M effector of murein hydrolase
HKALJCNE_03093 8.3e-193 yxaB GM Polysaccharide pyruvyl transferase
HKALJCNE_03094 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKALJCNE_03095 7.3e-127 gntR K transcriptional
HKALJCNE_03096 1.7e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HKALJCNE_03097 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HKALJCNE_03098 3.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKALJCNE_03099 6e-211 yttB EGP Major facilitator Superfamily
HKALJCNE_03100 4.5e-17 yttA 2.7.13.3 S Pfam Transposase IS66
HKALJCNE_03101 4.8e-23 yttA 2.7.13.3 S Pfam Transposase IS66
HKALJCNE_03102 0.0 bceB V ABC transporter (permease)
HKALJCNE_03103 5.6e-138 bceA V ABC transporter, ATP-binding protein
HKALJCNE_03104 7.8e-180 T PhoQ Sensor
HKALJCNE_03105 3.7e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_03106 2.1e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HKALJCNE_03107 5.9e-126 ytrE V ABC transporter, ATP-binding protein
HKALJCNE_03108 5.3e-149
HKALJCNE_03109 7.7e-164 P ABC-2 family transporter protein
HKALJCNE_03110 4.2e-161 ytrB P abc transporter atp-binding protein
HKALJCNE_03111 5.1e-66 ytrA K GntR family transcriptional regulator
HKALJCNE_03113 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HKALJCNE_03114 1.8e-189 yhcC S Fe-S oxidoreductase
HKALJCNE_03115 9.7e-106 ytqB J Putative rRNA methylase
HKALJCNE_03116 9.8e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HKALJCNE_03117 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HKALJCNE_03118 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HKALJCNE_03119 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HKALJCNE_03120 0.0 asnB 6.3.5.4 E Asparagine synthase
HKALJCNE_03121 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKALJCNE_03122 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HKALJCNE_03123 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HKALJCNE_03124 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HKALJCNE_03125 1e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HKALJCNE_03126 1.4e-144 ytlC P ABC transporter
HKALJCNE_03127 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HKALJCNE_03128 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HKALJCNE_03129 7e-63 ytkC S Bacteriophage holin family
HKALJCNE_03130 2.1e-76 dps P Belongs to the Dps family
HKALJCNE_03132 2.4e-72 ytkA S YtkA-like
HKALJCNE_03133 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKALJCNE_03134 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HKALJCNE_03135 3.6e-41 rpmE2 J Ribosomal protein L31
HKALJCNE_03136 6.8e-248 cydA 1.10.3.14 C oxidase, subunit
HKALJCNE_03137 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HKALJCNE_03138 1.1e-24 S Domain of Unknown Function (DUF1540)
HKALJCNE_03139 3.7e-149 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HKALJCNE_03140 2.6e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HKALJCNE_03141 2.8e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HKALJCNE_03142 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
HKALJCNE_03143 4.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HKALJCNE_03144 2.2e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKALJCNE_03145 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKALJCNE_03146 2.7e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HKALJCNE_03147 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HKALJCNE_03148 2.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
HKALJCNE_03149 2.6e-132 dksA T COG1734 DnaK suppressor protein
HKALJCNE_03150 1.6e-151 galU 2.7.7.9 M Nucleotidyl transferase
HKALJCNE_03151 1.6e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKALJCNE_03152 2e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HKALJCNE_03153 1.7e-232 ytcC M Glycosyltransferase Family 4
HKALJCNE_03155 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
HKALJCNE_03156 2e-216 cotSA M Glycosyl transferases group 1
HKALJCNE_03157 4.4e-205 cotI S Spore coat protein
HKALJCNE_03158 1.9e-75 tspO T membrane
HKALJCNE_03159 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKALJCNE_03160 2.3e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKALJCNE_03161 1.1e-176 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HKALJCNE_03162 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKALJCNE_03163 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKALJCNE_03164 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HKALJCNE_03165 2.4e-78 yrhD S Protein of unknown function (DUF1641)
HKALJCNE_03166 4.6e-35 yrhC S YrhC-like protein
HKALJCNE_03167 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKALJCNE_03168 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HKALJCNE_03169 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKALJCNE_03170 1.4e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HKALJCNE_03171 1e-25 yrzA S Protein of unknown function (DUF2536)
HKALJCNE_03172 4.6e-62 yrrS S Protein of unknown function (DUF1510)
HKALJCNE_03173 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HKALJCNE_03174 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKALJCNE_03175 8.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HKALJCNE_03176 1.8e-245 yegQ O COG0826 Collagenase and related proteases
HKALJCNE_03177 1.1e-172 yegQ O Peptidase U32
HKALJCNE_03178 3.8e-119 yrrM 2.1.1.104 S O-methyltransferase
HKALJCNE_03179 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKALJCNE_03180 1.2e-45 yrzB S Belongs to the UPF0473 family
HKALJCNE_03181 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKALJCNE_03182 1.7e-41 yrzL S Belongs to the UPF0297 family
HKALJCNE_03183 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKALJCNE_03184 7.8e-170 yrrI S AI-2E family transporter
HKALJCNE_03185 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKALJCNE_03186 1.4e-195 S Bacteriophage replication gene A protein (GPA)
HKALJCNE_03187 9.8e-42 S Phage protein C
HKALJCNE_03188 1.4e-78 S Bacteriophage scaffolding protein D
HKALJCNE_03189 3.3e-13 S Microvirus J protein
HKALJCNE_03190 5.4e-258 S Capsid protein (F protein)
HKALJCNE_03191 3.7e-96 S Major spike protein (G protein)
HKALJCNE_03192 2.7e-140 S Microvirus H protein (pilot protein)
HKALJCNE_03193 1.6e-21 yhaL S Sporulation protein YhaL
HKALJCNE_03194 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HKALJCNE_03195 0.0 yhaN L AAA domain
HKALJCNE_03196 4.8e-224 yhaO L DNA repair exonuclease
HKALJCNE_03197 4e-213 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HKALJCNE_03198 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
HKALJCNE_03199 2.4e-26 S YhzD-like protein
HKALJCNE_03200 4.6e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
HKALJCNE_03202 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HKALJCNE_03203 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HKALJCNE_03204 1.8e-292 hemZ H coproporphyrinogen III oxidase
HKALJCNE_03205 3.4e-155 yhaX S haloacid dehalogenase-like hydrolase
HKALJCNE_03206 3.2e-203 yhaZ L DNA alkylation repair enzyme
HKALJCNE_03207 9.5e-48 yheA S Belongs to the UPF0342 family
HKALJCNE_03208 2.2e-202 yheB S Belongs to the UPF0754 family
HKALJCNE_03210 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HKALJCNE_03211 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HKALJCNE_03212 2.4e-184 KLT serine threonine protein kinase
HKALJCNE_03213 6.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKALJCNE_03214 2.3e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKALJCNE_03215 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKALJCNE_03216 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKALJCNE_03217 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKALJCNE_03218 1.8e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HKALJCNE_03219 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKALJCNE_03220 9.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKALJCNE_03221 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HKALJCNE_03222 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HKALJCNE_03223 1.7e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKALJCNE_03224 6.5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKALJCNE_03225 7.9e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKALJCNE_03226 4.1e-30 yazB K transcriptional
HKALJCNE_03227 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKALJCNE_03228 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKALJCNE_03231 4.6e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HKALJCNE_03232 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HKALJCNE_03233 1.2e-84 gerD
HKALJCNE_03234 3e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HKALJCNE_03235 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKALJCNE_03236 2e-63 ybaK S Protein of unknown function (DUF2521)
HKALJCNE_03237 4.1e-144 ybaJ Q Methyltransferase domain
HKALJCNE_03238 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HKALJCNE_03239 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKALJCNE_03240 4.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKALJCNE_03241 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKALJCNE_03242 4.1e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKALJCNE_03243 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKALJCNE_03244 3.6e-58 rplQ J Ribosomal protein L17
HKALJCNE_03245 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKALJCNE_03246 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKALJCNE_03247 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKALJCNE_03248 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HKALJCNE_03249 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKALJCNE_03250 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HKALJCNE_03251 2.8e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKALJCNE_03252 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKALJCNE_03253 1.8e-72 rplO J binds to the 23S rRNA
HKALJCNE_03254 1.9e-23 rpmD J Ribosomal protein L30
HKALJCNE_03255 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKALJCNE_03256 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKALJCNE_03257 1.8e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKALJCNE_03258 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKALJCNE_03259 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKALJCNE_03260 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKALJCNE_03261 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKALJCNE_03262 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKALJCNE_03263 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKALJCNE_03264 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HKALJCNE_03265 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKALJCNE_03266 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKALJCNE_03267 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKALJCNE_03268 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKALJCNE_03269 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKALJCNE_03270 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKALJCNE_03271 3e-105 rplD J Forms part of the polypeptide exit tunnel
HKALJCNE_03272 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKALJCNE_03273 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HKALJCNE_03274 3.7e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HKALJCNE_03275 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKALJCNE_03276 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKALJCNE_03277 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKALJCNE_03278 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKALJCNE_03279 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HKALJCNE_03280 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKALJCNE_03281 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKALJCNE_03282 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HKALJCNE_03283 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKALJCNE_03284 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKALJCNE_03285 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKALJCNE_03286 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKALJCNE_03287 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
HKALJCNE_03288 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKALJCNE_03289 4.4e-115 sigH K Belongs to the sigma-70 factor family
HKALJCNE_03290 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HKALJCNE_03291 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKALJCNE_03292 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKALJCNE_03293 7.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKALJCNE_03294 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HKALJCNE_03295 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKALJCNE_03296 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKALJCNE_03297 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HKALJCNE_03298 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HKALJCNE_03299 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HKALJCNE_03300 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKALJCNE_03301 0.0 clpC O Belongs to the ClpA ClpB family
HKALJCNE_03302 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HKALJCNE_03303 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HKALJCNE_03304 2.9e-76 ctsR K Belongs to the CtsR family
HKALJCNE_03305 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HKALJCNE_03306 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
HKALJCNE_03307 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKALJCNE_03308 1.6e-54 arsR K ArsR family transcriptional regulator
HKALJCNE_03309 4.8e-145 yqcI S YqcI/YcgG family
HKALJCNE_03310 1.6e-96 S Tetratricopeptide repeat
HKALJCNE_03312 1.8e-29
HKALJCNE_03313 1.9e-163 yobL S Bacterial EndoU nuclease
HKALJCNE_03314 7.2e-24 S SMI1-KNR4 cell-wall
HKALJCNE_03315 4.1e-46
HKALJCNE_03316 2.1e-100 S Suppressor of fused protein (SUFU)
HKALJCNE_03318 5e-60
HKALJCNE_03320 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKALJCNE_03321 5.8e-68 S Bacteriophage holin family
HKALJCNE_03322 4.8e-165 xepA
HKALJCNE_03323 1.3e-23
HKALJCNE_03324 4.1e-56 xkdW S XkdW protein
HKALJCNE_03325 3.4e-221
HKALJCNE_03326 2.4e-38
HKALJCNE_03327 6.7e-99 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HKALJCNE_03328 3.4e-186 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HKALJCNE_03329 6.2e-49 xkdS S Protein of unknown function (DUF2634)
HKALJCNE_03330 1.8e-38 xkdR S Protein of unknown function (DUF2577)
HKALJCNE_03331 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HKALJCNE_03332 9.9e-113 xkdP S Lysin motif
HKALJCNE_03333 0.0 xkdO L Transglycosylase SLT domain
HKALJCNE_03334 2.8e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
HKALJCNE_03335 6.1e-76 xkdM S Phage tail tube protein
HKALJCNE_03336 2.2e-252 xkdK S Phage tail sheath C-terminal domain
HKALJCNE_03337 2.7e-25
HKALJCNE_03338 1.3e-75
HKALJCNE_03339 6.7e-87 S Bacteriophage HK97-gp10, putative tail-component
HKALJCNE_03340 9.7e-64 yqbH S Domain of unknown function (DUF3599)
HKALJCNE_03341 6e-67 S Protein of unknown function (DUF3199)
HKALJCNE_03342 5.1e-45 S YqbF, hypothetical protein domain
HKALJCNE_03343 4.6e-166 xkdG S Phage capsid family
HKALJCNE_03344 3.8e-115 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HKALJCNE_03345 2.6e-13
HKALJCNE_03346 3.1e-151 S Phage Mu protein F like protein
HKALJCNE_03347 3.7e-290 yqbA S portal protein
HKALJCNE_03348 7.3e-247 S phage terminase, large subunit
HKALJCNE_03349 5.2e-78 yqaS L DNA packaging
HKALJCNE_03350 6.2e-70 2.7.6.5 S Region found in RelA / SpoT proteins
HKALJCNE_03355 1e-78 L Transposase
HKALJCNE_03356 2.6e-75 S Beta protein
HKALJCNE_03357 2.4e-54 S Psort location Cytoplasmic, score
HKALJCNE_03358 6.8e-30 yqaO S Phage-like element PBSX protein XtrA
HKALJCNE_03359 1.4e-72 rusA L Endodeoxyribonuclease RusA
HKALJCNE_03361 9.7e-163 xkdC L IstB-like ATP binding protein
HKALJCNE_03362 9.8e-121 3.1.3.16 L DnaD domain protein
HKALJCNE_03363 1.2e-149 recT L RecT family
HKALJCNE_03364 4.9e-163 yqaJ L YqaJ-like viral recombinase domain
HKALJCNE_03368 1.2e-103
HKALJCNE_03370 9.1e-18 K Helix-turn-helix XRE-family like proteins
HKALJCNE_03371 1.1e-32 K sequence-specific DNA binding
HKALJCNE_03372 1.7e-09 S Protein of unknown function (DUF4064)
HKALJCNE_03373 5.2e-98 adk 2.7.4.3 F adenylate kinase activity
HKALJCNE_03374 8.9e-95 yqaB E IrrE N-terminal-like domain
HKALJCNE_03375 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKALJCNE_03378 7.9e-25 tatA U protein secretion
HKALJCNE_03379 1.8e-71
HKALJCNE_03380 7.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HKALJCNE_03383 1.8e-284 gerAA EG Spore germination protein
HKALJCNE_03384 2.3e-193 gerAB U Spore germination
HKALJCNE_03385 2.2e-216 gerLC S Spore germination protein
HKALJCNE_03386 1.4e-150 yndG S DoxX-like family
HKALJCNE_03387 5.4e-115 yndH S Domain of unknown function (DUF4166)
HKALJCNE_03388 1.5e-305 yndJ S YndJ-like protein
HKALJCNE_03390 6.8e-136 yndL S Replication protein
HKALJCNE_03391 1.7e-73 yndM S Protein of unknown function (DUF2512)
HKALJCNE_03392 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HKALJCNE_03393 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKALJCNE_03394 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HKALJCNE_03395 2.9e-111 yneB L resolvase
HKALJCNE_03396 1.3e-32 ynzC S UPF0291 protein
HKALJCNE_03397 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKALJCNE_03398 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HKALJCNE_03399 1.8e-28 yneF S UPF0154 protein
HKALJCNE_03400 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HKALJCNE_03401 2.3e-125 ccdA O cytochrome c biogenesis protein
HKALJCNE_03402 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HKALJCNE_03403 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HKALJCNE_03404 4.2e-74 yneK S Protein of unknown function (DUF2621)
HKALJCNE_03405 2.2e-63 hspX O Spore coat protein
HKALJCNE_03406 3.9e-19 sspP S Belongs to the SspP family
HKALJCNE_03407 2.5e-14 sspO S Belongs to the SspO family
HKALJCNE_03408 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKALJCNE_03409 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKALJCNE_03411 3.1e-08 sspN S Small acid-soluble spore protein N family
HKALJCNE_03412 3.9e-35 tlp S Belongs to the Tlp family
HKALJCNE_03413 1.2e-73 yneP S Thioesterase-like superfamily
HKALJCNE_03414 2.2e-53 yneQ
HKALJCNE_03415 4.1e-49 yneR S Belongs to the HesB IscA family
HKALJCNE_03416 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKALJCNE_03417 6.6e-69 yccU S CoA-binding protein
HKALJCNE_03418 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKALJCNE_03419 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKALJCNE_03420 2.3e-12
HKALJCNE_03421 8.6e-57 ynfC
HKALJCNE_03422 1.8e-251 agcS E Sodium alanine symporter
HKALJCNE_03423 1.2e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HKALJCNE_03425 6.9e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HKALJCNE_03426 2.3e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HKALJCNE_03427 2e-79 yngA S membrane
HKALJCNE_03428 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKALJCNE_03429 5.5e-104 yngC S membrane-associated protein
HKALJCNE_03430 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
HKALJCNE_03431 2.7e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKALJCNE_03432 2.4e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HKALJCNE_03433 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HKALJCNE_03434 8.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HKALJCNE_03435 1.1e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HKALJCNE_03436 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKALJCNE_03437 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HKALJCNE_03438 3.2e-302 yngK T Glycosyl hydrolase-like 10
HKALJCNE_03439 1.1e-63 yngL S Protein of unknown function (DUF1360)
HKALJCNE_03440 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HKALJCNE_03441 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_03442 4.5e-123 ywrJ
HKALJCNE_03443 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKALJCNE_03444 1.1e-169 alsR K LysR substrate binding domain
HKALJCNE_03445 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKALJCNE_03446 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HKALJCNE_03447 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HKALJCNE_03448 8e-48 ywsA S Protein of unknown function (DUF3892)
HKALJCNE_03449 8.7e-93 batE T Sh3 type 3 domain protein
HKALJCNE_03450 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HKALJCNE_03451 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HKALJCNE_03452 6.2e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HKALJCNE_03453 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKALJCNE_03454 1.8e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKALJCNE_03455 9.3e-178 rbsR K transcriptional
HKALJCNE_03456 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HKALJCNE_03457 8.6e-70 pgsC S biosynthesis protein
HKALJCNE_03458 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HKALJCNE_03459 3.6e-21 ywtC
HKALJCNE_03460 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKALJCNE_03461 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HKALJCNE_03462 2.3e-168 ywtF K Transcriptional regulator
HKALJCNE_03463 1.2e-247 ywtG EGP Major facilitator Superfamily
HKALJCNE_03464 2.7e-205 gerAC S Spore germination protein
HKALJCNE_03465 8.9e-193 gerBB E Spore germination protein
HKALJCNE_03466 3.7e-263 gerBA EG Spore germination protein
HKALJCNE_03467 3.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HKALJCNE_03468 8.9e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKALJCNE_03469 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKALJCNE_03470 3.3e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKALJCNE_03471 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKALJCNE_03472 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HKALJCNE_03473 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKALJCNE_03474 1.6e-87 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKALJCNE_03475 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HKALJCNE_03476 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKALJCNE_03477 1.5e-239 ggaA M Glycosyltransferase like family 2
HKALJCNE_03478 1.7e-204 msmX P Belongs to the ABC transporter superfamily
HKALJCNE_03479 3.3e-135 yurK K UTRA
HKALJCNE_03480 3.7e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HKALJCNE_03481 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HKALJCNE_03482 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
HKALJCNE_03483 4e-237 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HKALJCNE_03484 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HKALJCNE_03485 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HKALJCNE_03486 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HKALJCNE_03488 1.5e-37
HKALJCNE_03489 1.9e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKALJCNE_03490 3.5e-271 sufB O FeS cluster assembly
HKALJCNE_03491 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HKALJCNE_03492 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKALJCNE_03493 9.1e-245 sufD O assembly protein SufD
HKALJCNE_03494 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HKALJCNE_03495 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HKALJCNE_03496 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
HKALJCNE_03497 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HKALJCNE_03498 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKALJCNE_03499 1e-181 yaaC S YaaC-like Protein
HKALJCNE_03500 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKALJCNE_03501 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKALJCNE_03502 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKALJCNE_03503 5.7e-106 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HKALJCNE_03504 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKALJCNE_03505 1.1e-08
HKALJCNE_03506 4e-131 fliR N Flagellar biosynthetic protein FliR
HKALJCNE_03507 2.2e-36 fliQ N Role in flagellar biosynthesis
HKALJCNE_03508 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HKALJCNE_03509 1.3e-95 fliZ N Flagellar biosynthesis protein, FliO
HKALJCNE_03510 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HKALJCNE_03511 1.1e-174 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HKALJCNE_03512 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKALJCNE_03513 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HKALJCNE_03514 8.2e-140 flgG N Flagellar basal body rod
HKALJCNE_03515 1.7e-72 flgD N Flagellar basal body rod modification protein
HKALJCNE_03516 5.4e-214 fliK N Flagellar hook-length control protein
HKALJCNE_03517 5.5e-35 ylxF S MgtE intracellular N domain
HKALJCNE_03518 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HKALJCNE_03519 1.4e-240 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HKALJCNE_03520 9.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HKALJCNE_03521 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKALJCNE_03522 7e-255 fliF N The M ring may be actively involved in energy transduction
HKALJCNE_03523 1.9e-31 fliE N Flagellar hook-basal body
HKALJCNE_03524 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
HKALJCNE_03525 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HKALJCNE_03526 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HKALJCNE_03527 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKALJCNE_03528 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKALJCNE_03529 2.5e-169 xerC L tyrosine recombinase XerC
HKALJCNE_03530 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKALJCNE_03531 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKALJCNE_03532 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HKALJCNE_03533 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKALJCNE_03534 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKALJCNE_03535 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HKALJCNE_03536 1.5e-287 ylqG
HKALJCNE_03537 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKALJCNE_03538 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKALJCNE_03539 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKALJCNE_03540 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKALJCNE_03541 2.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKALJCNE_03542 1.4e-60 ylqD S YlqD protein
HKALJCNE_03543 4.5e-36 ylqC S Belongs to the UPF0109 family
HKALJCNE_03544 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKALJCNE_03545 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKALJCNE_03546 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKALJCNE_03547 6.4e-87
HKALJCNE_03548 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKALJCNE_03549 0.0 smc D Required for chromosome condensation and partitioning
HKALJCNE_03550 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKALJCNE_03551 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKALJCNE_03552 6.1e-129 IQ reductase
HKALJCNE_03553 1.2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKALJCNE_03554 2.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKALJCNE_03555 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HKALJCNE_03556 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKALJCNE_03557 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HKALJCNE_03558 5.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HKALJCNE_03559 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
HKALJCNE_03560 5.5e-59 asp S protein conserved in bacteria
HKALJCNE_03561 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKALJCNE_03562 2.6e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKALJCNE_03563 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKALJCNE_03564 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKALJCNE_03565 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HKALJCNE_03566 7.9e-140 stp 3.1.3.16 T phosphatase
HKALJCNE_03567 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKALJCNE_03568 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKALJCNE_03569 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKALJCNE_03570 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKALJCNE_03571 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKALJCNE_03572 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKALJCNE_03573 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKALJCNE_03574 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKALJCNE_03575 1.5e-40 ylzA S Belongs to the UPF0296 family
HKALJCNE_03576 2.4e-156 yloC S stress-induced protein
HKALJCNE_03577 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HKALJCNE_03578 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HKALJCNE_03579 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HKALJCNE_03580 4.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HKALJCNE_03581 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HKALJCNE_03582 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HKALJCNE_03583 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HKALJCNE_03584 1.8e-179 cysP P phosphate transporter
HKALJCNE_03585 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HKALJCNE_03587 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKALJCNE_03588 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKALJCNE_03589 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKALJCNE_03590 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HKALJCNE_03591 0.0 carB 6.3.5.5 F Belongs to the CarB family
HKALJCNE_03592 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKALJCNE_03593 3.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKALJCNE_03594 5.9e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKALJCNE_03595 3.8e-230 pyrP F Xanthine uracil
HKALJCNE_03596 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKALJCNE_03597 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKALJCNE_03598 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKALJCNE_03599 8.5e-63 dksA T COG1734 DnaK suppressor protein
HKALJCNE_03600 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKALJCNE_03601 2.6e-67 divIVA D Cell division initiation protein
HKALJCNE_03602 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HKALJCNE_03603 1.3e-39 yggT S membrane
HKALJCNE_03604 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKALJCNE_03605 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKALJCNE_03606 5.9e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HKALJCNE_03607 2.4e-37 ylmC S sporulation protein
HKALJCNE_03608 6.1e-254 argE 3.5.1.16 E Acetylornithine deacetylase
HKALJCNE_03609 5.3e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HKALJCNE_03610 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKALJCNE_03611 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKALJCNE_03612 1.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HKALJCNE_03613 0.0 bpr O COG1404 Subtilisin-like serine proteases
HKALJCNE_03614 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKALJCNE_03615 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKALJCNE_03616 6.2e-58 sbp S small basic protein
HKALJCNE_03617 6.6e-102 ylxX S protein conserved in bacteria
HKALJCNE_03618 2.4e-103 ylxW S protein conserved in bacteria
HKALJCNE_03619 7.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKALJCNE_03620 9e-167 murB 1.3.1.98 M cell wall formation
HKALJCNE_03621 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKALJCNE_03622 5.7e-186 spoVE D Belongs to the SEDS family
HKALJCNE_03623 3.8e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKALJCNE_03624 9.3e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKALJCNE_03625 1.7e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKALJCNE_03626 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HKALJCNE_03627 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HKALJCNE_03628 3.7e-44 ftsL D Essential cell division protein
HKALJCNE_03629 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKALJCNE_03630 2.9e-78 mraZ K Belongs to the MraZ family
HKALJCNE_03631 8.6e-159 ptxS K transcriptional
HKALJCNE_03632 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HKALJCNE_03633 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HKALJCNE_03634 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HKALJCNE_03635 4.6e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HKALJCNE_03636 1.4e-96 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKALJCNE_03637 1.1e-226 pbuX F xanthine
HKALJCNE_03638 9.1e-206 bcsA Q Naringenin-chalcone synthase
HKALJCNE_03639 5.1e-87 ypbQ S protein conserved in bacteria
HKALJCNE_03640 0.0 ypbR S Dynamin family
HKALJCNE_03641 8.5e-38 ypbS S Protein of unknown function (DUF2533)
HKALJCNE_03642 2e-07
HKALJCNE_03643 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HKALJCNE_03645 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
HKALJCNE_03646 8.6e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HKALJCNE_03647 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HKALJCNE_03648 2.6e-27 ypeQ S Zinc-finger
HKALJCNE_03649 8.1e-31 S Protein of unknown function (DUF2564)
HKALJCNE_03650 3.8e-16 degR
HKALJCNE_03651 1e-30 cspD K Cold-shock protein
HKALJCNE_03652 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HKALJCNE_03653 7.9e-114 yhzB S B3/4 domain
HKALJCNE_03654 3.5e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKALJCNE_03655 4.5e-174 yhbB S Putative amidase domain
HKALJCNE_03656 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKALJCNE_03657 1.3e-108 yhbD K Protein of unknown function (DUF4004)
HKALJCNE_03658 2.5e-63 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HKALJCNE_03659 1.8e-69 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HKALJCNE_03660 0.0 prkA T Ser protein kinase
HKALJCNE_03661 9.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HKALJCNE_03662 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_03663 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HKALJCNE_03665 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKALJCNE_03666 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKALJCNE_03667 3.2e-95 ypsA S Belongs to the UPF0398 family
HKALJCNE_03668 2.1e-235 yprB L RNase_H superfamily
HKALJCNE_03669 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HKALJCNE_03670 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HKALJCNE_03671 3.6e-70 hspX O Belongs to the small heat shock protein (HSP20) family
HKALJCNE_03672 1e-47 yppG S YppG-like protein
HKALJCNE_03674 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HKALJCNE_03677 5.9e-185 yppC S Protein of unknown function (DUF2515)
HKALJCNE_03678 2.1e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKALJCNE_03679 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HKALJCNE_03680 2.3e-92 ypoC
HKALJCNE_03681 8.3e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKALJCNE_03682 5.7e-129 dnaD L DNA replication protein DnaD
HKALJCNE_03683 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HKALJCNE_03684 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HKALJCNE_03685 2.2e-79 ypmB S protein conserved in bacteria
HKALJCNE_03686 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HKALJCNE_03687 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKALJCNE_03688 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HKALJCNE_03689 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HKALJCNE_03690 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HKALJCNE_03691 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKALJCNE_03692 1.1e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKALJCNE_03693 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HKALJCNE_03694 3.4e-129 bshB1 S proteins, LmbE homologs
HKALJCNE_03695 3.6e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HKALJCNE_03696 1.2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKALJCNE_03697 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HKALJCNE_03698 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HKALJCNE_03699 1e-142 ypjB S sporulation protein
HKALJCNE_03700 9.9e-98 ypjA S membrane
HKALJCNE_03701 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HKALJCNE_03702 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HKALJCNE_03703 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HKALJCNE_03704 4.2e-77 ypiF S Protein of unknown function (DUF2487)
HKALJCNE_03705 1.1e-98 ypiB S Belongs to the UPF0302 family
HKALJCNE_03706 2.7e-233 S COG0457 FOG TPR repeat
HKALJCNE_03707 1.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKALJCNE_03708 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HKALJCNE_03709 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKALJCNE_03710 6.8e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKALJCNE_03711 1.9e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKALJCNE_03712 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HKALJCNE_03713 5.2e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HKALJCNE_03714 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKALJCNE_03715 6.2e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKALJCNE_03716 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HKALJCNE_03717 3.2e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKALJCNE_03718 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKALJCNE_03719 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HKALJCNE_03720 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HKALJCNE_03721 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKALJCNE_03722 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKALJCNE_03723 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HKALJCNE_03724 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HKALJCNE_03725 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HKALJCNE_03726 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKALJCNE_03727 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HKALJCNE_03728 3.9e-136 yphF
HKALJCNE_03729 1.6e-18 yphE S Protein of unknown function (DUF2768)
HKALJCNE_03730 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKALJCNE_03731 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKALJCNE_03732 2.3e-27 ypzH
HKALJCNE_03733 2.5e-161 seaA S YIEGIA protein
HKALJCNE_03734 1.3e-102 yphA
HKALJCNE_03735 1e-07 S YpzI-like protein
HKALJCNE_03736 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKALJCNE_03737 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HKALJCNE_03738 1.2e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKALJCNE_03739 5e-21 S Family of unknown function (DUF5359)
HKALJCNE_03740 6.6e-111 ypfA M Flagellar protein YcgR
HKALJCNE_03741 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HKALJCNE_03742 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HKALJCNE_03743 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
HKALJCNE_03744 1.3e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HKALJCNE_03745 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKALJCNE_03746 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKALJCNE_03747 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HKALJCNE_03748 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HKALJCNE_03749 6.6e-75 ypbE M Lysin motif
HKALJCNE_03750 4.1e-99 ypbD S metal-dependent membrane protease
HKALJCNE_03751 1e-284 recQ 3.6.4.12 L DNA helicase
HKALJCNE_03752 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
HKALJCNE_03753 4.7e-41 fer C Ferredoxin
HKALJCNE_03754 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKALJCNE_03755 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKALJCNE_03756 7.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKALJCNE_03757 1.5e-184 rsiX
HKALJCNE_03758 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_03759 0.0 resE 2.7.13.3 T Histidine kinase
HKALJCNE_03760 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKALJCNE_03761 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HKALJCNE_03762 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HKALJCNE_03763 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HKALJCNE_03764 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKALJCNE_03765 1.9e-87 spmB S Spore maturation protein
HKALJCNE_03766 3.5e-103 spmA S Spore maturation protein
HKALJCNE_03767 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HKALJCNE_03768 7.6e-97 ypuI S Protein of unknown function (DUF3907)
HKALJCNE_03769 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKALJCNE_03770 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKALJCNE_03771 9.4e-92 ypuF S Domain of unknown function (DUF309)
HKALJCNE_03772 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKALJCNE_03773 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKALJCNE_03774 7e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKALJCNE_03775 2.2e-114 ribE 2.5.1.9 H Riboflavin synthase
HKALJCNE_03776 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKALJCNE_03777 7.8e-55 ypuD
HKALJCNE_03778 4e-93 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKALJCNE_03779 9.8e-14 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HKALJCNE_03781 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKALJCNE_03782 8.1e-149 ypuA S Secreted protein
HKALJCNE_03783 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKALJCNE_03784 1.4e-273 spoVAF EG Stage V sporulation protein AF
HKALJCNE_03785 1.4e-110 spoVAEA S stage V sporulation protein
HKALJCNE_03786 2.2e-57 spoVAEB S stage V sporulation protein
HKALJCNE_03787 9e-192 spoVAD I Stage V sporulation protein AD
HKALJCNE_03788 2.3e-78 spoVAC S stage V sporulation protein AC
HKALJCNE_03789 1e-67 spoVAB S Stage V sporulation protein AB
HKALJCNE_03790 9.6e-112 spoVAA S Stage V sporulation protein AA
HKALJCNE_03791 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKALJCNE_03792 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HKALJCNE_03793 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HKALJCNE_03794 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HKALJCNE_03795 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HKALJCNE_03796 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKALJCNE_03797 1.3e-165 xerD L recombinase XerD
HKALJCNE_03798 3.7e-37 S Protein of unknown function (DUF4227)
HKALJCNE_03799 2.4e-80 fur P Belongs to the Fur family
HKALJCNE_03800 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HKALJCNE_03801 1.9e-30 yqkK
HKALJCNE_03802 1e-240 mleA 1.1.1.38 C malic enzyme
HKALJCNE_03803 9.1e-235 mleN C Na H antiporter
HKALJCNE_03804 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HKALJCNE_03805 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HKALJCNE_03806 4.5e-58 ansR K Transcriptional regulator
HKALJCNE_03807 2.9e-218 yqxK 3.6.4.12 L DNA helicase
HKALJCNE_03808 5.8e-19 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HKALJCNE_03809 3.3e-97 ywrO S Flavodoxin-like fold
HKALJCNE_03810 9.1e-78 S Protein of unknown function with HXXEE motif
HKALJCNE_03811 5.7e-101 yrkJ S membrane transporter protein
HKALJCNE_03812 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
HKALJCNE_03813 1.6e-210 yrkH P Rhodanese Homology Domain
HKALJCNE_03814 4.9e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HKALJCNE_03815 2.5e-83 yrkE O DsrE/DsrF/DrsH-like family
HKALJCNE_03816 7.8e-39 yrkD S protein conserved in bacteria
HKALJCNE_03817 1.4e-106 yrkC G Cupin domain
HKALJCNE_03818 5.8e-149 bltR K helix_turn_helix, mercury resistance
HKALJCNE_03819 1.5e-209 blt EGP Major facilitator Superfamily
HKALJCNE_03820 9.1e-83 bltD 2.3.1.57 K FR47-like protein
HKALJCNE_03821 6.3e-230 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKALJCNE_03822 3.9e-16 S YrzO-like protein
HKALJCNE_03823 6e-169 yrdR EG EamA-like transporter family
HKALJCNE_03824 3.9e-159 yrdQ K Transcriptional regulator
HKALJCNE_03825 3.3e-197 trkA P Oxidoreductase
HKALJCNE_03826 2.2e-152 czcD P COG1230 Co Zn Cd efflux system component
HKALJCNE_03827 3.3e-226 brnQ E Component of the transport system for branched-chain amino acids
HKALJCNE_03828 1.2e-49 azlD E Branched-chain amino acid transport protein (AzlD)
HKALJCNE_03829 6.2e-137 azlC E AzlC protein
HKALJCNE_03830 2.6e-77 bkdR K helix_turn_helix ASNC type
HKALJCNE_03831 2.6e-40 yrdF K ribonuclease inhibitor
HKALJCNE_03832 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
HKALJCNE_03833 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKALJCNE_03834 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HKALJCNE_03835 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKALJCNE_03836 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HKALJCNE_03837 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKALJCNE_03838 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HKALJCNE_03839 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HKALJCNE_03840 1.3e-143 rsbR T Positive regulator of sigma-B
HKALJCNE_03841 5.2e-57 rsbS T antagonist
HKALJCNE_03842 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HKALJCNE_03843 3.5e-188 rsbU 3.1.3.3 KT phosphatase
HKALJCNE_03844 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
HKALJCNE_03845 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HKALJCNE_03846 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKALJCNE_03847 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HKALJCNE_03850 7.4e-82 ydcG S EVE domain
HKALJCNE_03851 6.1e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
HKALJCNE_03852 0.0 yhgF K COG2183 Transcriptional accessory protein
HKALJCNE_03853 3.4e-82 ydcK S Belongs to the SprT family
HKALJCNE_03855 6.7e-167 ygxA S Nucleotidyltransferase-like
HKALJCNE_03856 2.8e-55 ygzB S UPF0295 protein
HKALJCNE_03857 4e-80 perR P Belongs to the Fur family
HKALJCNE_03858 1.4e-86 bcp 1.11.1.15 O Peroxiredoxin
HKALJCNE_03859 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HKALJCNE_03860 8.7e-180 ygaE S Membrane
HKALJCNE_03861 3.1e-301 ygaD V ABC transporter
HKALJCNE_03862 1.3e-104 ygaC J Belongs to the UPF0374 family
HKALJCNE_03863 3.3e-37 ygaB S YgaB-like protein
HKALJCNE_03864 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HKALJCNE_03865 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKALJCNE_03866 6.9e-36 yfhS
HKALJCNE_03867 3.3e-210 mutY L A G-specific
HKALJCNE_03868 1.2e-185 yfhP S membrane-bound metal-dependent
HKALJCNE_03869 0.0 yfhO S Bacterial membrane protein YfhO
HKALJCNE_03870 4.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKALJCNE_03871 1.8e-169 yfhM S Alpha beta hydrolase
HKALJCNE_03872 3.5e-51 yfhL S SdpI/YhfL protein family
HKALJCNE_03873 2.1e-88 batE T Bacterial SH3 domain homologues
HKALJCNE_03874 1.3e-44 yfhJ S WVELL protein
HKALJCNE_03875 6.2e-20 sspK S reproduction
HKALJCNE_03876 9.5e-209 yfhI EGP Major facilitator Superfamily
HKALJCNE_03877 1.1e-50 yfhH S Protein of unknown function (DUF1811)
HKALJCNE_03878 1.6e-140 recX 2.4.1.337 GT4 S Modulates RecA activity
HKALJCNE_03879 2.7e-171 yfhF S nucleoside-diphosphate sugar epimerase
HKALJCNE_03881 2.1e-25 yfhD S YfhD-like protein
HKALJCNE_03882 3.9e-107 yfhC C nitroreductase
HKALJCNE_03883 1.1e-166 yfhB 5.3.3.17 S PhzF family
HKALJCNE_03884 1.6e-172 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_03885 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKALJCNE_03886 2.8e-174 yfiY P ABC transporter substrate-binding protein
HKALJCNE_03887 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKALJCNE_03888 4.9e-79 yfiV K transcriptional
HKALJCNE_03889 8.5e-282 yfiU EGP Major facilitator Superfamily
HKALJCNE_03890 3.6e-99 yfiT S Belongs to the metal hydrolase YfiT family
HKALJCNE_03891 1.8e-213 yfiS EGP Major facilitator Superfamily
HKALJCNE_03892 3.2e-107 yfiR K Transcriptional regulator
HKALJCNE_03893 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HKALJCNE_03894 5.6e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HKALJCNE_03895 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HKALJCNE_03896 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKALJCNE_03897 2.1e-51 ytwF P Sulfurtransferase
HKALJCNE_03898 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HKALJCNE_03899 4.4e-144 amyC P ABC transporter (permease)
HKALJCNE_03900 6.2e-168 amyD P ABC transporter
HKALJCNE_03901 2.8e-48 msmE G Bacterial extracellular solute-binding protein
HKALJCNE_03902 4.1e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKALJCNE_03903 1.2e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKALJCNE_03904 4.2e-110 hlyIII S protein, Hemolysin III
HKALJCNE_03905 1.6e-185 pspF K Transcriptional regulator
HKALJCNE_03906 4.7e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKALJCNE_03907 1.5e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HKALJCNE_03908 2.4e-223 yrkO P Protein of unknown function (DUF418)
HKALJCNE_03909 4.1e-127 T Transcriptional regulator
HKALJCNE_03910 1.3e-235 yrkQ T Histidine kinase
HKALJCNE_03911 2e-68 psiE S Protein PsiE homolog
HKALJCNE_03912 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HKALJCNE_03913 1.8e-142 focA P Formate nitrite
HKALJCNE_03916 1.2e-94 yrhH Q methyltransferase
HKALJCNE_03917 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HKALJCNE_03918 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HKALJCNE_03919 1.2e-43 yrhK S YrhK-like protein
HKALJCNE_03920 0.0 yrhL I Acyltransferase family
HKALJCNE_03921 1.2e-149 rsiV S Protein of unknown function (DUF3298)
HKALJCNE_03922 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HKALJCNE_03923 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HKALJCNE_03924 3.6e-106 yrhP E LysE type translocator
HKALJCNE_03925 4.9e-93 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HKALJCNE_03926 7.8e-114 ypjP S YpjP-like protein
HKALJCNE_03927 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HKALJCNE_03929 1.7e-75 yphP S Belongs to the UPF0403 family
HKALJCNE_03930 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HKALJCNE_03931 6.4e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
HKALJCNE_03932 1.3e-108 ypgQ S phosphohydrolase
HKALJCNE_03933 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HKALJCNE_03934 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKALJCNE_03935 9.9e-175 pit P phosphate transporter
HKALJCNE_03936 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HKALJCNE_03937 6.7e-23 spoIISB S Stage II sporulation protein SB
HKALJCNE_03938 1.2e-160 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKALJCNE_03939 2.7e-39 xhlB S SPP1 phage holin
HKALJCNE_03940 1.1e-38 xhlA S Haemolysin XhlA
HKALJCNE_03941 2.2e-151 xepA
HKALJCNE_03942 1.6e-21 xkdX
HKALJCNE_03943 2.2e-43 xkdW S XkdW protein
HKALJCNE_03944 0.0
HKALJCNE_03945 3.3e-40
HKALJCNE_03946 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HKALJCNE_03947 3.9e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HKALJCNE_03948 1.2e-68 xkdS S Protein of unknown function (DUF2634)
HKALJCNE_03949 3e-38 xkdR S Protein of unknown function (DUF2577)
HKALJCNE_03950 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HKALJCNE_03951 2.7e-118 xkdP S Lysin motif
HKALJCNE_03952 1.9e-228 xkdO L Transglycosylase SLT domain
HKALJCNE_03957 2.7e-149 ybdN
HKALJCNE_03959 5.7e-212 S Protein of unknown function (DUF1430)
HKALJCNE_03960 2.4e-78 V ATPases associated with a variety of cellular activities
HKALJCNE_03963 4.4e-29 K Transcriptional regulator
HKALJCNE_03964 2e-77 ygaO
HKALJCNE_03965 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKALJCNE_03967 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HKALJCNE_03968 1.9e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HKALJCNE_03969 1.5e-170 ssuA M Sulfonate ABC transporter
HKALJCNE_03970 5.7e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HKALJCNE_03971 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HKALJCNE_03973 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HKALJCNE_03974 1.7e-122 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HKALJCNE_03975 1.2e-26
HKALJCNE_03976 5e-142 spo0M S COG4326 Sporulation control protein
HKALJCNE_03978 6.2e-207 cotH M Spore Coat
HKALJCNE_03982 1.2e-91 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKALJCNE_03983 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)