ORF_ID e_value Gene_name EC_number CAZy COGs Description
NNECPOPP_00001 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_00002 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NNECPOPP_00003 2.3e-63 yngL S Protein of unknown function (DUF1360)
NNECPOPP_00004 7.7e-304 yngK T Glycosyl hydrolase-like 10
NNECPOPP_00005 3.1e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NNECPOPP_00006 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NNECPOPP_00007 5.6e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NNECPOPP_00008 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NNECPOPP_00009 5.2e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NNECPOPP_00010 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NNECPOPP_00011 2.9e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NNECPOPP_00012 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
NNECPOPP_00013 5.5e-104 yngC S membrane-associated protein
NNECPOPP_00014 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NNECPOPP_00015 2e-79 yngA S membrane
NNECPOPP_00016 1.3e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NNECPOPP_00017 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NNECPOPP_00019 2.4e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NNECPOPP_00020 5.3e-251 agcS E Sodium alanine symporter
NNECPOPP_00021 1.3e-57 ynfC
NNECPOPP_00022 2.3e-12
NNECPOPP_00023 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNECPOPP_00024 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNECPOPP_00025 6.6e-69 yccU S CoA-binding protein
NNECPOPP_00026 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NNECPOPP_00027 4.1e-49 yneR S Belongs to the HesB IscA family
NNECPOPP_00028 1.3e-53 yneQ
NNECPOPP_00029 1.2e-73 yneP S Thioesterase-like superfamily
NNECPOPP_00030 3.9e-35 tlp S Belongs to the Tlp family
NNECPOPP_00031 5.2e-08 sspN S Small acid-soluble spore protein N family
NNECPOPP_00033 7.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NNECPOPP_00034 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NNECPOPP_00035 2.5e-14 sspO S Belongs to the SspO family
NNECPOPP_00036 3.9e-19 sspP S Belongs to the SspP family
NNECPOPP_00037 9.4e-62 hspX O Spore coat protein
NNECPOPP_00038 7.2e-74 yneK S Protein of unknown function (DUF2621)
NNECPOPP_00039 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NNECPOPP_00040 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NNECPOPP_00041 7.1e-127 ccdA O cytochrome c biogenesis protein
NNECPOPP_00042 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NNECPOPP_00043 1.8e-28 yneF S UPF0154 protein
NNECPOPP_00044 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NNECPOPP_00045 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NNECPOPP_00046 1.3e-32 ynzC S UPF0291 protein
NNECPOPP_00047 4.5e-112 yneB L resolvase
NNECPOPP_00048 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NNECPOPP_00049 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NNECPOPP_00050 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NNECPOPP_00051 5.8e-74 yndM S Protein of unknown function (DUF2512)
NNECPOPP_00052 5.6e-115 yndL S Replication protein
NNECPOPP_00054 3e-306 yndJ S YndJ-like protein
NNECPOPP_00055 8e-114 yndH S Domain of unknown function (DUF4166)
NNECPOPP_00056 2.8e-151 yndG S DoxX-like family
NNECPOPP_00057 6.1e-219 gerLC S Spore germination protein
NNECPOPP_00058 3.8e-196 gerAB U Spore germination
NNECPOPP_00059 3.2e-281 gerAA EG Spore germination protein
NNECPOPP_00063 1.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NNECPOPP_00064 1.8e-71
NNECPOPP_00065 6.7e-24 tatA U protein secretion
NNECPOPP_00068 8.2e-123 S Domain of unknown function, YrpD
NNECPOPP_00069 1.1e-163 S Thymidylate synthase
NNECPOPP_00072 5.2e-15
NNECPOPP_00073 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NNECPOPP_00074 6.3e-84 yncE S Protein of unknown function (DUF2691)
NNECPOPP_00075 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNECPOPP_00076 4e-254 iolT EGP Major facilitator Superfamily
NNECPOPP_00077 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
NNECPOPP_00078 2.5e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NNECPOPP_00079 2.2e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NNECPOPP_00080 2.1e-213 xylR GK ROK family
NNECPOPP_00081 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NNECPOPP_00082 3.3e-253 xynT G MFS/sugar transport protein
NNECPOPP_00083 2.4e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NNECPOPP_00084 1.7e-108 ynaE S Domain of unknown function (DUF3885)
NNECPOPP_00085 1.5e-22 K Cro/C1-type HTH DNA-binding domain
NNECPOPP_00086 3.9e-07 S Uncharacterised protein family (UPF0715)
NNECPOPP_00087 1.1e-56 S CAAX protease self-immunity
NNECPOPP_00090 2.9e-96 ynaD J Acetyltransferase (GNAT) domain
NNECPOPP_00092 6e-215 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
NNECPOPP_00093 1.1e-192 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NNECPOPP_00094 4.2e-119 H Methionine biosynthesis protein MetW
NNECPOPP_00095 3.7e-93 M Glycosyltransferase like family
NNECPOPP_00096 2.7e-69 Q Collagen triple helix repeat (20 copies)
NNECPOPP_00097 1e-31
NNECPOPP_00098 5e-10
NNECPOPP_00101 4.7e-35 S Terminase
NNECPOPP_00102 1.8e-79 L phage terminase small subunit
NNECPOPP_00103 4.4e-48 V HNH endonuclease
NNECPOPP_00108 3.1e-18 N HicA toxin of bacterial toxin-antitoxin,
NNECPOPP_00109 5.4e-66 S regulation of transcription, DNA-dependent
NNECPOPP_00110 1.1e-07 S FRG
NNECPOPP_00111 2.5e-40 wecC 1.1.1.336 M ArpU family transcriptional regulator
NNECPOPP_00115 1.6e-21
NNECPOPP_00116 1.4e-101 dnaB 3.6.4.12 L replicative DNA helicase
NNECPOPP_00117 2.3e-38 L Arm DNA-binding domain
NNECPOPP_00118 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
NNECPOPP_00119 1.1e-68 glnR K transcriptional
NNECPOPP_00120 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NNECPOPP_00121 3.9e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NNECPOPP_00122 1.7e-176 spoVK O stage V sporulation protein K
NNECPOPP_00123 1.8e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NNECPOPP_00124 2e-109 ymaB
NNECPOPP_00125 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNECPOPP_00126 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNECPOPP_00127 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NNECPOPP_00128 4.5e-22 ymzA
NNECPOPP_00129 8.2e-23
NNECPOPP_00130 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NNECPOPP_00131 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NNECPOPP_00132 2.1e-46 ymaF S YmaF family
NNECPOPP_00134 4.9e-51 ebrA P Small Multidrug Resistance protein
NNECPOPP_00135 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NNECPOPP_00136 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
NNECPOPP_00137 2.1e-126 ymaC S Replication protein
NNECPOPP_00138 1.9e-07 K Transcriptional regulator
NNECPOPP_00139 1.7e-251 aprX O Belongs to the peptidase S8 family
NNECPOPP_00140 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
NNECPOPP_00141 4.4e-61 ymzB
NNECPOPP_00142 9.7e-233 cypA C Cytochrome P450
NNECPOPP_00143 0.0 pks13 HQ Beta-ketoacyl synthase
NNECPOPP_00144 0.0 dhbF IQ polyketide synthase
NNECPOPP_00145 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NNECPOPP_00146 0.0 pfaA Q Polyketide synthase of type I
NNECPOPP_00147 0.0 rhiB IQ polyketide synthase
NNECPOPP_00148 3e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NNECPOPP_00149 1.1e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
NNECPOPP_00150 1.3e-245 pksG 2.3.3.10 I synthase
NNECPOPP_00151 3.9e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNECPOPP_00152 1.4e-37 acpK IQ Phosphopantetheine attachment site
NNECPOPP_00153 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NNECPOPP_00154 9.6e-183 pksD Q Acyl transferase domain
NNECPOPP_00156 3.7e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NNECPOPP_00157 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NNECPOPP_00158 3.2e-107 pksA K Transcriptional regulator
NNECPOPP_00159 3.5e-97 ymcC S Membrane
NNECPOPP_00161 5.1e-70 S Regulatory protein YrvL
NNECPOPP_00162 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NNECPOPP_00163 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NNECPOPP_00164 2.2e-88 cotE S Spore coat protein
NNECPOPP_00165 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NNECPOPP_00166 8.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NNECPOPP_00167 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NNECPOPP_00168 3.9e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NNECPOPP_00169 1.2e-36 spoVS S Stage V sporulation protein S
NNECPOPP_00170 1.9e-152 ymdB S protein conserved in bacteria
NNECPOPP_00171 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NNECPOPP_00172 2.3e-215 pbpX V Beta-lactamase
NNECPOPP_00173 2.4e-187 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NNECPOPP_00174 1.6e-235 cinA 3.5.1.42 S Belongs to the CinA family
NNECPOPP_00175 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNECPOPP_00176 6.1e-123 ymfM S protein conserved in bacteria
NNECPOPP_00177 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NNECPOPP_00178 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NNECPOPP_00179 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NNECPOPP_00180 9.2e-242 ymfH S zinc protease
NNECPOPP_00181 1.2e-233 ymfF S Peptidase M16
NNECPOPP_00182 6.5e-205 ymfD EGP Major facilitator Superfamily
NNECPOPP_00183 1.4e-133 ymfC K Transcriptional regulator
NNECPOPP_00184 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NNECPOPP_00185 4.4e-32 S YlzJ-like protein
NNECPOPP_00186 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NNECPOPP_00187 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNECPOPP_00188 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NNECPOPP_00189 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NNECPOPP_00190 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NNECPOPP_00191 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NNECPOPP_00192 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NNECPOPP_00193 2.6e-42 ymxH S YlmC YmxH family
NNECPOPP_00194 4.4e-233 pepR S Belongs to the peptidase M16 family
NNECPOPP_00195 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NNECPOPP_00196 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NNECPOPP_00197 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NNECPOPP_00198 3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NNECPOPP_00199 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NNECPOPP_00200 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NNECPOPP_00201 3.9e-44 ylxP S protein conserved in bacteria
NNECPOPP_00202 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NNECPOPP_00203 3.1e-47 ylxQ J ribosomal protein
NNECPOPP_00204 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NNECPOPP_00205 1.1e-203 nusA K Participates in both transcription termination and antitermination
NNECPOPP_00206 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NNECPOPP_00207 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNECPOPP_00208 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NNECPOPP_00209 7.7e-233 rasP M zinc metalloprotease
NNECPOPP_00210 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NNECPOPP_00211 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NNECPOPP_00212 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NNECPOPP_00213 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NNECPOPP_00214 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NNECPOPP_00215 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NNECPOPP_00216 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NNECPOPP_00217 2.1e-77 ylxL
NNECPOPP_00218 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNECPOPP_00219 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NNECPOPP_00220 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NNECPOPP_00221 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NNECPOPP_00222 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NNECPOPP_00223 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NNECPOPP_00224 1.8e-156 flhG D Belongs to the ParA family
NNECPOPP_00225 1.5e-200 flhF N Flagellar biosynthesis regulator FlhF
NNECPOPP_00226 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NNECPOPP_00227 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NNECPOPP_00228 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NNECPOPP_00229 2.2e-36 fliQ N Role in flagellar biosynthesis
NNECPOPP_00230 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NNECPOPP_00231 8.7e-95 fliZ N Flagellar biosynthesis protein, FliO
NNECPOPP_00232 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NNECPOPP_00233 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NNECPOPP_00234 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NNECPOPP_00235 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NNECPOPP_00236 1.6e-135 flgG N Flagellar basal body rod
NNECPOPP_00237 2.3e-72 flgD N Flagellar basal body rod modification protein
NNECPOPP_00238 4.3e-219 fliK N Flagellar hook-length control protein
NNECPOPP_00239 2.2e-36 ylxF S MgtE intracellular N domain
NNECPOPP_00240 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NNECPOPP_00241 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NNECPOPP_00242 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NNECPOPP_00243 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NNECPOPP_00244 2.4e-255 fliF N The M ring may be actively involved in energy transduction
NNECPOPP_00245 1.9e-31 fliE N Flagellar hook-basal body
NNECPOPP_00246 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
NNECPOPP_00247 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NNECPOPP_00248 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NNECPOPP_00249 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NNECPOPP_00250 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NNECPOPP_00251 2.5e-169 xerC L tyrosine recombinase XerC
NNECPOPP_00252 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NNECPOPP_00253 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNECPOPP_00254 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NNECPOPP_00255 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NNECPOPP_00256 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NNECPOPP_00257 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NNECPOPP_00258 1.4e-285 ylqG
NNECPOPP_00259 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNECPOPP_00260 6.7e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NNECPOPP_00261 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NNECPOPP_00262 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NNECPOPP_00263 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NNECPOPP_00264 6.3e-61 ylqD S YlqD protein
NNECPOPP_00265 4.5e-36 ylqC S Belongs to the UPF0109 family
NNECPOPP_00266 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NNECPOPP_00267 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NNECPOPP_00268 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NNECPOPP_00269 2.9e-87
NNECPOPP_00270 1.7e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NNECPOPP_00271 0.0 smc D Required for chromosome condensation and partitioning
NNECPOPP_00272 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NNECPOPP_00273 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNECPOPP_00274 6.1e-129 IQ reductase
NNECPOPP_00275 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NNECPOPP_00276 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NNECPOPP_00277 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NNECPOPP_00278 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NNECPOPP_00279 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NNECPOPP_00280 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NNECPOPP_00281 1.5e-300 yloV S kinase related to dihydroxyacetone kinase
NNECPOPP_00282 5.5e-59 asp S protein conserved in bacteria
NNECPOPP_00283 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NNECPOPP_00284 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NNECPOPP_00285 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NNECPOPP_00286 2.5e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NNECPOPP_00287 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NNECPOPP_00288 1.6e-140 stp 3.1.3.16 T phosphatase
NNECPOPP_00289 2e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NNECPOPP_00290 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NNECPOPP_00291 7.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NNECPOPP_00292 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNECPOPP_00293 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNECPOPP_00294 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NNECPOPP_00295 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NNECPOPP_00296 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NNECPOPP_00297 1.5e-40 ylzA S Belongs to the UPF0296 family
NNECPOPP_00298 3.1e-156 yloC S stress-induced protein
NNECPOPP_00299 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NNECPOPP_00300 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NNECPOPP_00301 2.4e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NNECPOPP_00302 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NNECPOPP_00303 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NNECPOPP_00304 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NNECPOPP_00305 2.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NNECPOPP_00306 2.7e-178 cysP P phosphate transporter
NNECPOPP_00307 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NNECPOPP_00308 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NNECPOPP_00309 5.2e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NNECPOPP_00310 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NNECPOPP_00311 4.1e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NNECPOPP_00312 0.0 carB 6.3.5.5 F Belongs to the CarB family
NNECPOPP_00313 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NNECPOPP_00314 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NNECPOPP_00315 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NNECPOPP_00316 4.9e-230 pyrP F Xanthine uracil
NNECPOPP_00317 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NNECPOPP_00318 2.5e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NNECPOPP_00319 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NNECPOPP_00320 2.9e-63 dksA T COG1734 DnaK suppressor protein
NNECPOPP_00321 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NNECPOPP_00322 2.6e-67 divIVA D Cell division initiation protein
NNECPOPP_00323 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NNECPOPP_00324 1.3e-39 yggT S membrane
NNECPOPP_00325 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NNECPOPP_00326 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NNECPOPP_00327 2.7e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NNECPOPP_00328 2.4e-37 ylmC S sporulation protein
NNECPOPP_00329 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
NNECPOPP_00330 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NNECPOPP_00331 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNECPOPP_00332 3e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNECPOPP_00333 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NNECPOPP_00334 0.0 bpr O COG1404 Subtilisin-like serine proteases
NNECPOPP_00335 2.9e-202 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NNECPOPP_00336 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NNECPOPP_00337 6.2e-58 sbp S small basic protein
NNECPOPP_00338 1.8e-91 ylxX S protein conserved in bacteria
NNECPOPP_00339 4.1e-103 ylxW S protein conserved in bacteria
NNECPOPP_00340 1e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NNECPOPP_00341 9e-167 murB 1.3.1.98 M cell wall formation
NNECPOPP_00342 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NNECPOPP_00343 5.7e-186 spoVE D Belongs to the SEDS family
NNECPOPP_00344 5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NNECPOPP_00345 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NNECPOPP_00346 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NNECPOPP_00347 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NNECPOPP_00348 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NNECPOPP_00349 3.7e-44 ftsL D Essential cell division protein
NNECPOPP_00350 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NNECPOPP_00351 2.9e-78 mraZ K Belongs to the MraZ family
NNECPOPP_00352 2.7e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NNECPOPP_00353 6.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNECPOPP_00354 1.5e-88 ylbP K n-acetyltransferase
NNECPOPP_00355 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NNECPOPP_00356 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NNECPOPP_00357 1.9e-89 yceD S metal-binding, possibly nucleic acid-binding protein
NNECPOPP_00359 4e-234 ylbM S Belongs to the UPF0348 family
NNECPOPP_00360 2e-186 ylbL T Belongs to the peptidase S16 family
NNECPOPP_00361 1.7e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
NNECPOPP_00362 1.2e-219 ylbJ S Sporulation integral membrane protein YlbJ
NNECPOPP_00363 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NNECPOPP_00364 6e-97 rsmD 2.1.1.171 L Methyltransferase
NNECPOPP_00365 2.2e-38 ylbG S UPF0298 protein
NNECPOPP_00366 1.8e-75 ylbF S Belongs to the UPF0342 family
NNECPOPP_00367 6.7e-37 ylbE S YlbE-like protein
NNECPOPP_00368 1.3e-61 ylbD S Putative coat protein
NNECPOPP_00369 2.8e-199 ylbC S protein with SCP PR1 domains
NNECPOPP_00370 2.6e-74 ylbB T COG0517 FOG CBS domain
NNECPOPP_00371 7e-62 ylbA S YugN-like family
NNECPOPP_00372 8.8e-167 ctaG S cytochrome c oxidase
NNECPOPP_00373 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NNECPOPP_00374 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NNECPOPP_00375 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NNECPOPP_00376 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NNECPOPP_00377 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NNECPOPP_00378 4.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NNECPOPP_00379 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NNECPOPP_00380 1.7e-213 ftsW D Belongs to the SEDS family
NNECPOPP_00381 8.7e-44 ylaN S Belongs to the UPF0358 family
NNECPOPP_00382 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NNECPOPP_00383 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NNECPOPP_00384 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NNECPOPP_00385 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNECPOPP_00386 2.5e-32 ylaI S protein conserved in bacteria
NNECPOPP_00387 4.2e-47 ylaH S YlaH-like protein
NNECPOPP_00388 0.0 typA T GTP-binding protein TypA
NNECPOPP_00389 8.2e-22 S Family of unknown function (DUF5325)
NNECPOPP_00390 4.1e-38 ylaE
NNECPOPP_00391 7.1e-12 sigC S Putative zinc-finger
NNECPOPP_00392 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_00393 3e-41 ylaB
NNECPOPP_00394 0.0 ylaA
NNECPOPP_00395 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NNECPOPP_00396 1e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NNECPOPP_00397 3.4e-77 ykzC S Acetyltransferase (GNAT) family
NNECPOPP_00398 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
NNECPOPP_00399 7.1e-26 ykzI
NNECPOPP_00400 7.1e-118 yktB S Belongs to the UPF0637 family
NNECPOPP_00401 1.6e-42 yktA S Belongs to the UPF0223 family
NNECPOPP_00402 3.5e-277 speA 4.1.1.19 E Arginine
NNECPOPP_00403 3.8e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NNECPOPP_00404 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNECPOPP_00405 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNECPOPP_00406 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNECPOPP_00407 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNECPOPP_00408 9.4e-113 recN L Putative cell-wall binding lipoprotein
NNECPOPP_00410 2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNECPOPP_00411 1.4e-147 ykrA S hydrolases of the HAD superfamily
NNECPOPP_00412 8.2e-31 ykzG S Belongs to the UPF0356 family
NNECPOPP_00413 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNECPOPP_00414 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NNECPOPP_00415 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NNECPOPP_00416 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NNECPOPP_00417 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NNECPOPP_00418 1.5e-43 abrB K of stationary sporulation gene expression
NNECPOPP_00419 7.7e-183 mreB D Rod-share determining protein MreBH
NNECPOPP_00420 1.1e-12 S Uncharacterized protein YkpC
NNECPOPP_00421 5.9e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NNECPOPP_00422 5.3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNECPOPP_00423 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNECPOPP_00424 1.8e-38 ykoA
NNECPOPP_00425 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NNECPOPP_00426 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NNECPOPP_00427 1.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NNECPOPP_00428 3.1e-136 fruR K Transcriptional regulator
NNECPOPP_00429 2.8e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NNECPOPP_00430 2.5e-124 macB V ABC transporter, ATP-binding protein
NNECPOPP_00431 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NNECPOPP_00432 1.5e-116 yknW S Yip1 domain
NNECPOPP_00433 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NNECPOPP_00434 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NNECPOPP_00435 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NNECPOPP_00436 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NNECPOPP_00437 1.1e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NNECPOPP_00438 2.4e-245 moeA 2.10.1.1 H molybdopterin
NNECPOPP_00439 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NNECPOPP_00440 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NNECPOPP_00441 7.9e-145 yknT
NNECPOPP_00442 5.8e-95 rok K Repressor of ComK
NNECPOPP_00443 4.1e-80 ykuV CO thiol-disulfide
NNECPOPP_00444 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NNECPOPP_00445 8.8e-142 ykuT M Mechanosensitive ion channel
NNECPOPP_00446 9e-37 ykuS S Belongs to the UPF0180 family
NNECPOPP_00447 4.9e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NNECPOPP_00448 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NNECPOPP_00449 3.2e-80 fld C Flavodoxin
NNECPOPP_00450 1.2e-174 ykuO
NNECPOPP_00451 1e-84 fld C Flavodoxin domain
NNECPOPP_00452 3.5e-168 ccpC K Transcriptional regulator
NNECPOPP_00453 1.6e-76 ykuL S CBS domain
NNECPOPP_00454 3.9e-27 ykzF S Antirepressor AbbA
NNECPOPP_00455 1.3e-93 ykuK S Ribonuclease H-like
NNECPOPP_00456 3.9e-37 ykuJ S protein conserved in bacteria
NNECPOPP_00457 5.2e-234 ykuI T Diguanylate phosphodiesterase
NNECPOPP_00458 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_00459 9.4e-166 ykuE S Metallophosphoesterase
NNECPOPP_00460 1.8e-87 ykuD S protein conserved in bacteria
NNECPOPP_00461 2.3e-232 ykuC EGP Major facilitator Superfamily
NNECPOPP_00462 1.7e-84 ykyB S YkyB-like protein
NNECPOPP_00463 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NNECPOPP_00464 1.8e-14
NNECPOPP_00465 1.8e-220 patA 2.6.1.1 E Aminotransferase
NNECPOPP_00466 0.0 pilS 2.7.13.3 T Histidine kinase
NNECPOPP_00467 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NNECPOPP_00468 8e-124 ykwD J protein with SCP PR1 domains
NNECPOPP_00469 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NNECPOPP_00470 1.6e-261 mcpC NT chemotaxis protein
NNECPOPP_00471 3.9e-125 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNECPOPP_00472 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
NNECPOPP_00473 7.2e-39 splA S Transcriptional regulator
NNECPOPP_00474 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNECPOPP_00475 2.1e-39 ptsH G phosphocarrier protein HPr
NNECPOPP_00476 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NNECPOPP_00477 7.6e-128 glcT K antiterminator
NNECPOPP_00479 8.3e-179 ykvZ 5.1.1.1 K Transcriptional regulator
NNECPOPP_00480 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NNECPOPP_00481 2.3e-09
NNECPOPP_00482 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NNECPOPP_00483 3e-87 stoA CO thiol-disulfide
NNECPOPP_00484 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNECPOPP_00485 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NNECPOPP_00486 2.8e-28
NNECPOPP_00487 6e-25 ykvS S protein conserved in bacteria
NNECPOPP_00488 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NNECPOPP_00489 7.6e-161 G Glycosyl hydrolases family 18
NNECPOPP_00490 3.5e-35 3.5.1.104 M LysM domain
NNECPOPP_00491 2.9e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
NNECPOPP_00492 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
NNECPOPP_00493 2.2e-60 ykvN K HxlR-like helix-turn-helix
NNECPOPP_00494 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NNECPOPP_00495 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NNECPOPP_00496 1.4e-80 queD 4.1.2.50, 4.2.3.12 H synthase
NNECPOPP_00497 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NNECPOPP_00498 1.2e-178 ykvI S membrane
NNECPOPP_00499 0.0 clpE O Belongs to the ClpA ClpB family
NNECPOPP_00500 1e-137 motA N flagellar motor
NNECPOPP_00501 2.5e-125 motB N Flagellar motor protein
NNECPOPP_00502 1.3e-75 ykvE K transcriptional
NNECPOPP_00503 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NNECPOPP_00504 1.8e-64 eag
NNECPOPP_00505 6.4e-09 S Spo0E like sporulation regulatory protein
NNECPOPP_00506 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
NNECPOPP_00507 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NNECPOPP_00508 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NNECPOPP_00509 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NNECPOPP_00510 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NNECPOPP_00511 1.1e-231 mtnE 2.6.1.83 E Aminotransferase
NNECPOPP_00512 4.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NNECPOPP_00513 1.1e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NNECPOPP_00514 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NNECPOPP_00516 4.6e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNECPOPP_00517 0.0 kinE 2.7.13.3 T Histidine kinase
NNECPOPP_00518 9.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NNECPOPP_00519 1.4e-18 ykzE
NNECPOPP_00520 1.2e-10 ydfR S Protein of unknown function (DUF421)
NNECPOPP_00521 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NNECPOPP_00522 3.5e-155 htpX O Belongs to the peptidase M48B family
NNECPOPP_00523 1.5e-124 ykrK S Domain of unknown function (DUF1836)
NNECPOPP_00524 1.9e-26 sspD S small acid-soluble spore protein
NNECPOPP_00525 7.7e-115 rsgI S Anti-sigma factor N-terminus
NNECPOPP_00526 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNECPOPP_00527 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NNECPOPP_00528 2.7e-109 ykoX S membrane-associated protein
NNECPOPP_00529 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NNECPOPP_00530 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NNECPOPP_00531 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NNECPOPP_00532 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NNECPOPP_00533 0.0 ykoS
NNECPOPP_00534 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NNECPOPP_00535 1.1e-98 ykoP G polysaccharide deacetylase
NNECPOPP_00536 3.3e-219 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NNECPOPP_00537 1.3e-81 mhqR K transcriptional
NNECPOPP_00538 3.4e-25 ykoL
NNECPOPP_00539 1.3e-17
NNECPOPP_00540 1.4e-53 tnrA K transcriptional
NNECPOPP_00541 2.2e-222 mgtE P Acts as a magnesium transporter
NNECPOPP_00544 1.8e-84 ykoJ S Peptidase propeptide and YPEB domain
NNECPOPP_00545 3.6e-112 ykoI S Peptidase propeptide and YPEB domain
NNECPOPP_00546 1.3e-238 ykoH 2.7.13.3 T Histidine kinase
NNECPOPP_00547 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_00548 6.7e-110 ykoF S YKOF-related Family
NNECPOPP_00549 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
NNECPOPP_00550 2.8e-307 P ABC transporter, ATP-binding protein
NNECPOPP_00551 1.3e-134 ykoC P Cobalt transport protein
NNECPOPP_00552 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNECPOPP_00553 2.5e-175 isp O Belongs to the peptidase S8 family
NNECPOPP_00554 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NNECPOPP_00555 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NNECPOPP_00557 4.2e-71 ohrB O Organic hydroperoxide resistance protein
NNECPOPP_00558 4.4e-74 ohrR K COG1846 Transcriptional regulators
NNECPOPP_00559 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NNECPOPP_00560 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NNECPOPP_00561 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNECPOPP_00562 1.1e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NNECPOPP_00563 7e-50 ykkD P Multidrug resistance protein
NNECPOPP_00564 3.5e-55 ykkC P Multidrug resistance protein
NNECPOPP_00565 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NNECPOPP_00566 3.9e-98 ykkA S Protein of unknown function (DUF664)
NNECPOPP_00567 2.7e-129 ykjA S Protein of unknown function (DUF421)
NNECPOPP_00568 7.2e-09
NNECPOPP_00569 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NNECPOPP_00570 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NNECPOPP_00571 5.9e-160 ykgA E Amidinotransferase
NNECPOPP_00572 6.9e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
NNECPOPP_00573 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
NNECPOPP_00574 2.2e-165 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NNECPOPP_00575 3.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NNECPOPP_00576 5.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NNECPOPP_00578 0.0 dppE E ABC transporter substrate-binding protein
NNECPOPP_00579 1.3e-187 dppD P Belongs to the ABC transporter superfamily
NNECPOPP_00580 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNECPOPP_00581 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNECPOPP_00582 5.1e-153 dppA E D-aminopeptidase
NNECPOPP_00583 1.4e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NNECPOPP_00584 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNECPOPP_00586 3.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NNECPOPP_00587 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NNECPOPP_00588 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NNECPOPP_00589 4.4e-239 steT E amino acid
NNECPOPP_00590 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NNECPOPP_00591 5.8e-175 pit P phosphate transporter
NNECPOPP_00592 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NNECPOPP_00593 2.5e-22 spoIISB S Stage II sporulation protein SB
NNECPOPP_00595 7.7e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NNECPOPP_00596 2.7e-39 xhlB S SPP1 phage holin
NNECPOPP_00597 6.2e-39 xhlA S Haemolysin XhlA
NNECPOPP_00598 2.4e-150 xepA
NNECPOPP_00599 4.2e-22 xkdX
NNECPOPP_00600 4.2e-42 xkdW S XkdW protein
NNECPOPP_00601 0.0
NNECPOPP_00602 1.5e-40
NNECPOPP_00603 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NNECPOPP_00604 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NNECPOPP_00605 1.4e-69 xkdS S Protein of unknown function (DUF2634)
NNECPOPP_00606 5.7e-37 xkdR S Protein of unknown function (DUF2577)
NNECPOPP_00607 5.3e-181 yqbQ 3.2.1.96 G NLP P60 protein
NNECPOPP_00608 3.7e-122 xkdP S Lysin motif
NNECPOPP_00609 0.0 xkdO L Transglycosylase SLT domain
NNECPOPP_00610 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NNECPOPP_00611 6.1e-76 xkdM S Phage tail tube protein
NNECPOPP_00612 5.5e-256 xkdK S Phage tail sheath C-terminal domain
NNECPOPP_00613 9.3e-77 xkdJ
NNECPOPP_00614 1.9e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
NNECPOPP_00615 1.5e-64 yqbH S Domain of unknown function (DUF3599)
NNECPOPP_00616 8.7e-63 yqbG S Protein of unknown function (DUF3199)
NNECPOPP_00617 5.8e-169 xkdG S Phage capsid family
NNECPOPP_00618 4.1e-134 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NNECPOPP_00619 5.4e-286 yqbA S portal protein
NNECPOPP_00620 1.4e-253 xtmB S phage terminase, large subunit
NNECPOPP_00621 3.8e-137 xtmA L phage terminase small subunit
NNECPOPP_00622 2.2e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NNECPOPP_00623 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NNECPOPP_00626 4.1e-118 xkdC L Bacterial dnaA protein
NNECPOPP_00627 2.9e-156 xkdB K sequence-specific DNA binding
NNECPOPP_00629 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NNECPOPP_00630 1e-110 xkdA E IrrE N-terminal-like domain
NNECPOPP_00631 4.4e-160 ydbD P Catalase
NNECPOPP_00632 2.1e-111 yjqB S Pfam:DUF867
NNECPOPP_00633 1.8e-60 yjqA S Bacterial PH domain
NNECPOPP_00634 2.1e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NNECPOPP_00635 5.3e-40 S YCII-related domain
NNECPOPP_00637 1e-212 S response regulator aspartate phosphatase
NNECPOPP_00638 1e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NNECPOPP_00639 2.3e-78 yjoA S DinB family
NNECPOPP_00640 2.2e-129 MA20_18170 S membrane transporter protein
NNECPOPP_00641 7.8e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NNECPOPP_00642 1.1e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NNECPOPP_00643 2.3e-184 exuR K transcriptional
NNECPOPP_00644 3.7e-227 exuT G Sugar (and other) transporter
NNECPOPP_00645 4.9e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_00646 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NNECPOPP_00647 6.9e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NNECPOPP_00648 7.9e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NNECPOPP_00649 7.1e-248 yjmB G symporter YjmB
NNECPOPP_00650 1e-278 uxaC 5.3.1.12 G glucuronate isomerase
NNECPOPP_00651 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
NNECPOPP_00652 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NNECPOPP_00653 1.7e-90 yjlB S Cupin domain
NNECPOPP_00654 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
NNECPOPP_00655 4.9e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NNECPOPP_00656 6.2e-121 ybbM S transport system, permease component
NNECPOPP_00657 9e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NNECPOPP_00658 8.2e-30
NNECPOPP_00659 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NNECPOPP_00660 2.2e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NNECPOPP_00662 3.2e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NNECPOPP_00663 8.7e-07 S Domain of unknown function (DUF4352)
NNECPOPP_00664 1.6e-94 yjgD S Protein of unknown function (DUF1641)
NNECPOPP_00665 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NNECPOPP_00666 1.3e-102 yjgB S Domain of unknown function (DUF4309)
NNECPOPP_00667 1.5e-43 T PhoQ Sensor
NNECPOPP_00668 3.4e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
NNECPOPP_00669 2.3e-20 yjfB S Putative motility protein
NNECPOPP_00670 3e-81 S Protein of unknown function (DUF2690)
NNECPOPP_00671 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
NNECPOPP_00673 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NNECPOPP_00674 3.5e-52 yjdJ S Domain of unknown function (DUF4306)
NNECPOPP_00675 7.1e-29 S Domain of unknown function (DUF4177)
NNECPOPP_00676 9.8e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NNECPOPP_00678 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NNECPOPP_00679 7e-50 yjdF S Protein of unknown function (DUF2992)
NNECPOPP_00680 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NNECPOPP_00681 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NNECPOPP_00682 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NNECPOPP_00684 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
NNECPOPP_00685 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
NNECPOPP_00687 1.7e-49 S YolD-like protein
NNECPOPP_00688 7.4e-75 S Protein of unknown function (DUF3800)
NNECPOPP_00689 2.6e-245 M nucleic acid phosphodiester bond hydrolysis
NNECPOPP_00690 1.7e-40
NNECPOPP_00692 5.4e-212 yjcL S Protein of unknown function (DUF819)
NNECPOPP_00693 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
NNECPOPP_00694 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NNECPOPP_00695 1.4e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NNECPOPP_00696 8.5e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
NNECPOPP_00697 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NNECPOPP_00698 5.1e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNECPOPP_00699 1.7e-38
NNECPOPP_00700 0.0 yjcD 3.6.4.12 L DNA helicase
NNECPOPP_00701 2.9e-38 spoVIF S Stage VI sporulation protein F
NNECPOPP_00704 1.9e-56 yjcA S Protein of unknown function (DUF1360)
NNECPOPP_00705 7.2e-49 cotV S Spore Coat Protein X and V domain
NNECPOPP_00706 7.4e-23 cotW
NNECPOPP_00707 1.2e-67 cotX S Spore Coat Protein X and V domain
NNECPOPP_00708 7.6e-96 cotY S Spore coat protein Z
NNECPOPP_00709 4.4e-82 cotZ S Spore coat protein
NNECPOPP_00710 1.4e-52 yjbX S Spore coat protein
NNECPOPP_00711 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NNECPOPP_00712 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NNECPOPP_00713 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NNECPOPP_00714 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NNECPOPP_00715 2.6e-29 thiS H thiamine diphosphate biosynthetic process
NNECPOPP_00716 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
NNECPOPP_00717 3.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NNECPOPP_00718 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NNECPOPP_00719 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNECPOPP_00720 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NNECPOPP_00721 3.7e-157 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NNECPOPP_00722 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNECPOPP_00723 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NNECPOPP_00724 2.7e-61 yjbL S Belongs to the UPF0738 family
NNECPOPP_00725 5.1e-99 yjbK S protein conserved in bacteria
NNECPOPP_00726 3.1e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NNECPOPP_00727 3.7e-72 yjbI S Bacterial-like globin
NNECPOPP_00728 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NNECPOPP_00730 1.8e-20
NNECPOPP_00731 0.0 pepF E oligoendopeptidase F
NNECPOPP_00732 2.1e-221 yjbF S Competence protein
NNECPOPP_00733 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NNECPOPP_00734 1e-111 yjbE P Integral membrane protein TerC family
NNECPOPP_00735 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NNECPOPP_00736 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNECPOPP_00737 2.4e-204 yjbB EGP Major Facilitator Superfamily
NNECPOPP_00738 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NNECPOPP_00739 6.8e-198 oppD P Belongs to the ABC transporter superfamily
NNECPOPP_00740 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNECPOPP_00741 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNECPOPP_00742 0.0 oppA E ABC transporter substrate-binding protein
NNECPOPP_00743 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NNECPOPP_00744 1.9e-146 yjbA S Belongs to the UPF0736 family
NNECPOPP_00745 6.7e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNECPOPP_00746 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNECPOPP_00747 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NNECPOPP_00748 6.5e-187 appF E Belongs to the ABC transporter superfamily
NNECPOPP_00749 1.8e-184 appD P Belongs to the ABC transporter superfamily
NNECPOPP_00750 1.1e-149 yjaZ O Zn-dependent protease
NNECPOPP_00751 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNECPOPP_00752 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNECPOPP_00753 2.7e-22 yjzB
NNECPOPP_00754 3.6e-18 comZ S ComZ
NNECPOPP_00755 2.5e-183 med S Transcriptional activator protein med
NNECPOPP_00756 1.8e-101 yjaV
NNECPOPP_00757 3.1e-141 yjaU I carboxylic ester hydrolase activity
NNECPOPP_00758 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NNECPOPP_00759 9.5e-28 yjzC S YjzC-like protein
NNECPOPP_00760 3.6e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NNECPOPP_00761 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NNECPOPP_00762 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NNECPOPP_00763 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NNECPOPP_00764 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NNECPOPP_00765 2.2e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NNECPOPP_00766 1.8e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NNECPOPP_00767 1.7e-88 norB G Major Facilitator Superfamily
NNECPOPP_00768 2.9e-268 yitY C D-arabinono-1,4-lactone oxidase
NNECPOPP_00769 1.3e-21 pilT S Proteolipid membrane potential modulator
NNECPOPP_00770 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NNECPOPP_00771 1.9e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NNECPOPP_00772 4.6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NNECPOPP_00774 1.2e-17 S Protein of unknown function (DUF3813)
NNECPOPP_00775 5e-73 ipi S Intracellular proteinase inhibitor
NNECPOPP_00776 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NNECPOPP_00777 8.4e-159 yitS S protein conserved in bacteria
NNECPOPP_00778 3.2e-308 nprB 3.4.24.28 E Peptidase M4
NNECPOPP_00779 1.4e-44 yitR S Domain of unknown function (DUF3784)
NNECPOPP_00780 5.9e-95
NNECPOPP_00781 1.5e-58 K Transcriptional regulator PadR-like family
NNECPOPP_00782 7.6e-97 S Sporulation delaying protein SdpA
NNECPOPP_00783 1.4e-170
NNECPOPP_00784 8.5e-94
NNECPOPP_00785 6.9e-161 cvfB S protein conserved in bacteria
NNECPOPP_00786 3.3e-54 yajQ S Belongs to the UPF0234 family
NNECPOPP_00787 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NNECPOPP_00788 1.2e-71 yjcF S Acetyltransferase (GNAT) domain
NNECPOPP_00789 4.8e-154 yitH K Acetyltransferase (GNAT) domain
NNECPOPP_00790 2e-228 yitG EGP Major facilitator Superfamily
NNECPOPP_00791 1e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NNECPOPP_00792 8.6e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNECPOPP_00793 5.4e-141 yitD 4.4.1.19 S synthase
NNECPOPP_00794 2.3e-122 comB 3.1.3.71 H Belongs to the ComB family
NNECPOPP_00795 1e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NNECPOPP_00796 1.8e-231 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NNECPOPP_00797 4.2e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NNECPOPP_00798 9.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NNECPOPP_00799 2e-35 mcbG S Pentapeptide repeats (9 copies)
NNECPOPP_00800 9.9e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNECPOPP_00801 7.8e-106 argO S Lysine exporter protein LysE YggA
NNECPOPP_00802 8.2e-93 yisT S DinB family
NNECPOPP_00803 5.4e-192 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NNECPOPP_00805 2.4e-184 purR K helix_turn _helix lactose operon repressor
NNECPOPP_00806 3.5e-160 yisR K Transcriptional regulator
NNECPOPP_00807 4e-243 yisQ V Mate efflux family protein
NNECPOPP_00808 3.7e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NNECPOPP_00809 4.7e-88 yizA S Damage-inducible protein DinB
NNECPOPP_00810 0.0 asnO 6.3.5.4 E Asparagine synthase
NNECPOPP_00811 1.4e-100 yisN S Protein of unknown function (DUF2777)
NNECPOPP_00812 0.0 wprA O Belongs to the peptidase S8 family
NNECPOPP_00813 3e-57 yisL S UPF0344 protein
NNECPOPP_00814 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NNECPOPP_00815 5e-173 cotH M Spore Coat
NNECPOPP_00816 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NNECPOPP_00817 1.9e-33 gerPA S Spore germination protein
NNECPOPP_00818 4e-34 gerPB S cell differentiation
NNECPOPP_00819 1.8e-54 gerPC S Spore germination protein
NNECPOPP_00820 6.3e-24 gerPD S Spore germination protein
NNECPOPP_00821 3e-66 gerPE S Spore germination protein GerPE
NNECPOPP_00822 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NNECPOPP_00823 4.8e-50 yisB V COG1403 Restriction endonuclease
NNECPOPP_00824 0.0 sbcC L COG0419 ATPase involved in DNA repair
NNECPOPP_00825 1.4e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NNECPOPP_00826 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NNECPOPP_00827 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NNECPOPP_00828 2.2e-78 yhjR S Rubrerythrin
NNECPOPP_00829 0.0 S Sugar transport-related sRNA regulator N-term
NNECPOPP_00830 5.8e-214 EGP Transmembrane secretion effector
NNECPOPP_00831 1.6e-200 abrB S membrane
NNECPOPP_00832 1.3e-187 yhjM 5.1.1.1 K Transcriptional regulator
NNECPOPP_00833 6.3e-254 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NNECPOPP_00834 4e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NNECPOPP_00835 4.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NNECPOPP_00836 2.6e-214 glcP G Major Facilitator Superfamily
NNECPOPP_00837 4.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NNECPOPP_00838 1.8e-281 yhjG CH FAD binding domain
NNECPOPP_00839 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NNECPOPP_00840 9.1e-110 yhjE S SNARE associated Golgi protein
NNECPOPP_00841 6.7e-60 yhjD
NNECPOPP_00842 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NNECPOPP_00843 7.5e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNECPOPP_00844 3.3e-40 yhjA S Excalibur calcium-binding domain
NNECPOPP_00845 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
NNECPOPP_00846 4.2e-109 comK K Competence transcription factor
NNECPOPP_00847 1.3e-32 yhzC S IDEAL
NNECPOPP_00848 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_00849 1e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NNECPOPP_00850 1.7e-182 hemAT NT chemotaxis protein
NNECPOPP_00851 5e-91 bioY S BioY family
NNECPOPP_00852 1.1e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NNECPOPP_00853 2.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
NNECPOPP_00854 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NNECPOPP_00855 4.3e-159 yfmC M Periplasmic binding protein
NNECPOPP_00856 2.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
NNECPOPP_00857 1.7e-78 VY92_01935 K acetyltransferase
NNECPOPP_00858 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NNECPOPP_00859 1.2e-241 yhfN 3.4.24.84 O Peptidase M48
NNECPOPP_00860 7.4e-65 yhfM
NNECPOPP_00861 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NNECPOPP_00862 1.7e-111 yhfK GM NmrA-like family
NNECPOPP_00863 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NNECPOPP_00864 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NNECPOPP_00865 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNECPOPP_00866 1.1e-71 3.4.13.21 S ASCH
NNECPOPP_00867 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NNECPOPP_00868 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
NNECPOPP_00869 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNECPOPP_00870 9.2e-216 yhgE S YhgE Pip N-terminal domain protein
NNECPOPP_00871 5.4e-101 yhgD K Transcriptional regulator
NNECPOPP_00872 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NNECPOPP_00873 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NNECPOPP_00874 2.2e-201 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NNECPOPP_00875 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NNECPOPP_00876 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NNECPOPP_00877 4.9e-35 1.15.1.2 C Rubrerythrin
NNECPOPP_00878 5.1e-246 yhfA C membrane
NNECPOPP_00879 2.3e-226 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NNECPOPP_00880 1.2e-113 ecsC S EcsC protein family
NNECPOPP_00881 5.4e-215 ecsB U ABC transporter
NNECPOPP_00882 2.3e-136 ecsA V transporter (ATP-binding protein)
NNECPOPP_00883 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NNECPOPP_00884 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NNECPOPP_00885 3.6e-80 trpP S Tryptophan transporter TrpP
NNECPOPP_00886 7e-39 yhaH S YtxH-like protein
NNECPOPP_00887 3.9e-113 hpr K Negative regulator of protease production and sporulation
NNECPOPP_00888 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NNECPOPP_00889 8.7e-90 yhaK S Putative zincin peptidase
NNECPOPP_00890 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NNECPOPP_00891 1.6e-21 yhaL S Sporulation protein YhaL
NNECPOPP_00892 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NNECPOPP_00893 0.0 yhaN L AAA domain
NNECPOPP_00894 1.2e-222 yhaO L DNA repair exonuclease
NNECPOPP_00895 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NNECPOPP_00896 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
NNECPOPP_00897 2.4e-26 S YhzD-like protein
NNECPOPP_00898 2.6e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
NNECPOPP_00900 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NNECPOPP_00901 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NNECPOPP_00902 1.8e-292 hemZ H coproporphyrinogen III oxidase
NNECPOPP_00903 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NNECPOPP_00904 7e-203 yhaZ L DNA alkylation repair enzyme
NNECPOPP_00905 9.5e-48 yheA S Belongs to the UPF0342 family
NNECPOPP_00906 2.6e-200 yheB S Belongs to the UPF0754 family
NNECPOPP_00907 6.2e-215 yheC HJ YheC/D like ATP-grasp
NNECPOPP_00908 4.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NNECPOPP_00909 3.8e-36 yheE S Family of unknown function (DUF5342)
NNECPOPP_00910 6.3e-28 sspB S spore protein
NNECPOPP_00911 4e-110 yheG GM NAD(P)H-binding
NNECPOPP_00912 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NNECPOPP_00913 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NNECPOPP_00914 1.7e-83 nhaX T Belongs to the universal stress protein A family
NNECPOPP_00915 1.6e-228 nhaC C Na H antiporter
NNECPOPP_00916 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NNECPOPP_00917 1.9e-147 yheN G deacetylase
NNECPOPP_00918 2.5e-84 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NNECPOPP_00919 5.6e-203 yhdY M Mechanosensitive ion channel
NNECPOPP_00921 8.1e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NNECPOPP_00922 2.8e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNECPOPP_00923 4.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNECPOPP_00924 9.6e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NNECPOPP_00925 1.7e-221 yhdR 2.6.1.1 E Aminotransferase
NNECPOPP_00926 4.1e-74 cueR K transcriptional
NNECPOPP_00927 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NNECPOPP_00928 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NNECPOPP_00929 2.6e-191 yhdN C Aldo keto reductase
NNECPOPP_00930 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_00931 2.5e-200 yhdL S Sigma factor regulator N-terminal
NNECPOPP_00932 8.1e-45 yhdK S Sigma-M inhibitor protein
NNECPOPP_00933 1.6e-73 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNECPOPP_00934 5.7e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNECPOPP_00935 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NNECPOPP_00936 1e-249 yhdG E amino acid
NNECPOPP_00937 3e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_00938 1.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
NNECPOPP_00939 3.8e-162 citR K Transcriptional regulator
NNECPOPP_00940 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NNECPOPP_00941 9.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NNECPOPP_00942 4.8e-276 ycgB S Stage V sporulation protein R
NNECPOPP_00943 1.3e-237 ygxB M Conserved TM helix
NNECPOPP_00944 1e-75 nsrR K Transcriptional regulator
NNECPOPP_00945 8.7e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NNECPOPP_00946 1.8e-53 yhdC S Protein of unknown function (DUF3889)
NNECPOPP_00947 1.2e-38 yhdB S YhdB-like protein
NNECPOPP_00948 3.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NNECPOPP_00949 1.7e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNECPOPP_00950 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
NNECPOPP_00951 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NNECPOPP_00952 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NNECPOPP_00953 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NNECPOPP_00954 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NNECPOPP_00955 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NNECPOPP_00956 2.1e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNECPOPP_00957 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NNECPOPP_00958 5.1e-119 yhcW 5.4.2.6 S hydrolase
NNECPOPP_00959 9.9e-68 yhcV S COG0517 FOG CBS domain
NNECPOPP_00960 9.3e-68 yhcU S Family of unknown function (DUF5365)
NNECPOPP_00961 1.9e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NNECPOPP_00962 3.5e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NNECPOPP_00963 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NNECPOPP_00964 1.5e-99 yhcQ M Spore coat protein
NNECPOPP_00965 7.3e-167 yhcP
NNECPOPP_00966 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNECPOPP_00967 4.1e-40 yhcM
NNECPOPP_00968 1.2e-218 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNECPOPP_00969 1.3e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NNECPOPP_00970 4.1e-150 metQ M Belongs to the nlpA lipoprotein family
NNECPOPP_00971 1e-30 cspB K Cold-shock protein
NNECPOPP_00972 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NNECPOPP_00973 2.2e-165 yhcH V ABC transporter, ATP-binding protein
NNECPOPP_00974 4e-122 yhcG V ABC transporter, ATP-binding protein
NNECPOPP_00975 1.9e-59 yhcF K Transcriptional regulator
NNECPOPP_00976 4.1e-56
NNECPOPP_00977 2.8e-37 yhcC
NNECPOPP_00978 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NNECPOPP_00979 3.1e-271 yhcA EGP Major facilitator Superfamily
NNECPOPP_00980 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NNECPOPP_00981 2.2e-76 yhbI K DNA-binding transcription factor activity
NNECPOPP_00982 2.5e-225 yhbH S Belongs to the UPF0229 family
NNECPOPP_00983 0.0 prkA T Ser protein kinase
NNECPOPP_00984 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NNECPOPP_00985 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NNECPOPP_00986 1.8e-108 yhbD K Protein of unknown function (DUF4004)
NNECPOPP_00987 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NNECPOPP_00988 1.7e-176 yhbB S Putative amidase domain
NNECPOPP_00989 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NNECPOPP_00990 7.4e-112 yhzB S B3/4 domain
NNECPOPP_00992 4.4e-29 K Transcriptional regulator
NNECPOPP_00993 2.6e-77 ygaO
NNECPOPP_00994 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNECPOPP_00996 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NNECPOPP_00997 3.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NNECPOPP_00998 1.1e-170 ssuA M Sulfonate ABC transporter
NNECPOPP_00999 1.1e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NNECPOPP_01000 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NNECPOPP_01002 1.9e-261 ygaK C Berberine and berberine like
NNECPOPP_01003 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NNECPOPP_01004 1.4e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NNECPOPP_01005 1.2e-26
NNECPOPP_01006 2.7e-143 spo0M S COG4326 Sporulation control protein
NNECPOPP_01010 2e-08
NNECPOPP_01018 7.8e-08
NNECPOPP_01023 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_01024 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_01025 3.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NNECPOPP_01026 6.9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
NNECPOPP_01027 2.3e-246 yoeA V MATE efflux family protein
NNECPOPP_01028 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NNECPOPP_01030 5e-96 L Integrase
NNECPOPP_01031 3e-34 yoeD G Helix-turn-helix domain
NNECPOPP_01032 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NNECPOPP_01033 1.7e-154 gltR1 K Transcriptional regulator
NNECPOPP_01034 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NNECPOPP_01035 8.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NNECPOPP_01036 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NNECPOPP_01037 7.8e-155 gltC K Transcriptional regulator
NNECPOPP_01038 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNECPOPP_01039 5.6e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNECPOPP_01040 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NNECPOPP_01041 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_01042 9.8e-41 yoxC S Bacterial protein of unknown function (DUF948)
NNECPOPP_01043 1.3e-142 yoxB
NNECPOPP_01044 9.2e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NNECPOPP_01045 1.8e-234 yoaB EGP Major facilitator Superfamily
NNECPOPP_01046 5.1e-281 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NNECPOPP_01047 2.9e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNECPOPP_01048 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNECPOPP_01049 6.5e-34 yoaF
NNECPOPP_01050 5e-08 ywlA S Uncharacterised protein family (UPF0715)
NNECPOPP_01051 2.6e-13
NNECPOPP_01052 1.5e-38 S Protein of unknown function (DUF4025)
NNECPOPP_01053 1.1e-178 mcpU NT methyl-accepting chemotaxis protein
NNECPOPP_01054 6.2e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NNECPOPP_01055 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NNECPOPP_01056 2.3e-111 yoaK S Membrane
NNECPOPP_01057 8.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NNECPOPP_01058 6e-131 yoqW S Belongs to the SOS response-associated peptidase family
NNECPOPP_01060 9.6e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
NNECPOPP_01062 1.2e-145 yoaP 3.1.3.18 K YoaP-like
NNECPOPP_01063 2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
NNECPOPP_01065 5e-87
NNECPOPP_01066 7.1e-172 yoaR V vancomycin resistance protein
NNECPOPP_01067 1.1e-73 yoaS S Protein of unknown function (DUF2975)
NNECPOPP_01068 1.6e-36 yozG K Transcriptional regulator
NNECPOPP_01069 6.3e-148 yoaT S Protein of unknown function (DUF817)
NNECPOPP_01070 5.6e-158 yoaU K LysR substrate binding domain
NNECPOPP_01071 1.3e-157 yijE EG EamA-like transporter family
NNECPOPP_01072 2.7e-76 yoaW
NNECPOPP_01073 7.8e-117 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NNECPOPP_01074 1.2e-166 bla 3.5.2.6 V beta-lactamase
NNECPOPP_01077 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NNECPOPP_01078 6.9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NNECPOPP_01079 8.8e-37 S TM2 domain
NNECPOPP_01080 1.7e-54 K Helix-turn-helix
NNECPOPP_01082 9.5e-50 FG Scavenger mRNA decapping enzyme C-term binding
NNECPOPP_01083 7.3e-116
NNECPOPP_01085 8.7e-32 isp O Subtilase family
NNECPOPP_01092 1.3e-28 S Bacillus cereus group antimicrobial protein
NNECPOPP_01094 1.1e-61 yoqH M LysM domain
NNECPOPP_01098 9.2e-206 S aspartate phosphatase
NNECPOPP_01100 5.2e-79 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNECPOPP_01101 4.2e-33 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNECPOPP_01103 3.5e-46
NNECPOPP_01106 2.9e-91 yokH G SMI1 / KNR4 family
NNECPOPP_01107 2.9e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NNECPOPP_01108 4.6e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NNECPOPP_01109 1.6e-134 yobQ K helix_turn_helix, arabinose operon control protein
NNECPOPP_01110 4.1e-141 yobR 2.3.1.1 J FR47-like protein
NNECPOPP_01111 3.3e-98 yobS K Transcriptional regulator
NNECPOPP_01112 2.8e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NNECPOPP_01113 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
NNECPOPP_01114 4.2e-175 yobV K WYL domain
NNECPOPP_01115 7.4e-92 yobW
NNECPOPP_01116 1e-51 czrA K transcriptional
NNECPOPP_01117 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NNECPOPP_01118 1.5e-92 yozB S membrane
NNECPOPP_01119 6.4e-145
NNECPOPP_01120 1.6e-93 yocC
NNECPOPP_01121 2.2e-187 yocD 3.4.17.13 V peptidase S66
NNECPOPP_01122 7.7e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NNECPOPP_01123 2.7e-197 desK 2.7.13.3 T Histidine kinase
NNECPOPP_01124 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNECPOPP_01126 6e-112 yocH CBM50 M COG1388 FOG LysM repeat
NNECPOPP_01127 0.0 recQ 3.6.4.12 L DNA helicase
NNECPOPP_01128 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NNECPOPP_01129 3.3e-83 dksA T general stress protein
NNECPOPP_01130 5.4e-53 yocL
NNECPOPP_01131 6.2e-32
NNECPOPP_01132 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NNECPOPP_01133 1.1e-40 yozN
NNECPOPP_01134 4.2e-36 yocN
NNECPOPP_01135 4.2e-56 yozO S Bacterial PH domain
NNECPOPP_01136 2.7e-31 yozC
NNECPOPP_01137 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NNECPOPP_01138 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NNECPOPP_01139 5.1e-164 sodA 1.15.1.1 P Superoxide dismutase
NNECPOPP_01140 1.7e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NNECPOPP_01141 1.1e-165 yocS S -transporter
NNECPOPP_01142 3.2e-191 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NNECPOPP_01143 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NNECPOPP_01144 0.0 yojO P Von Willebrand factor
NNECPOPP_01145 2.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
NNECPOPP_01146 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NNECPOPP_01147 7.9e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NNECPOPP_01148 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NNECPOPP_01149 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNECPOPP_01151 2.7e-244 norM V Multidrug efflux pump
NNECPOPP_01152 1.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNECPOPP_01153 2.1e-125 yojG S deacetylase
NNECPOPP_01154 2.2e-60 yojF S Protein of unknown function (DUF1806)
NNECPOPP_01155 1.5e-43
NNECPOPP_01156 2.5e-161 rarD S -transporter
NNECPOPP_01157 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
NNECPOPP_01158 1e-08
NNECPOPP_01159 6.5e-206 gntP EG COG2610 H gluconate symporter and related permeases
NNECPOPP_01160 8e-64 yodA S tautomerase
NNECPOPP_01161 4.4e-55 yodB K transcriptional
NNECPOPP_01162 1.4e-107 yodC C nitroreductase
NNECPOPP_01163 6.5e-113 mhqD S Carboxylesterase
NNECPOPP_01164 1.4e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
NNECPOPP_01165 6.2e-28 S Protein of unknown function (DUF3311)
NNECPOPP_01166 1.7e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNECPOPP_01167 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NNECPOPP_01168 6.3e-128 yodH Q Methyltransferase
NNECPOPP_01169 1.5e-23 yodI
NNECPOPP_01170 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NNECPOPP_01171 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NNECPOPP_01172 5.3e-09
NNECPOPP_01173 3.6e-54 yodL S YodL-like
NNECPOPP_01174 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
NNECPOPP_01175 2.8e-24 yozD S YozD-like protein
NNECPOPP_01177 1.6e-123 yodN
NNECPOPP_01178 1.4e-36 yozE S Belongs to the UPF0346 family
NNECPOPP_01179 2.9e-47 yokU S YokU-like protein, putative antitoxin
NNECPOPP_01180 5.1e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NNECPOPP_01181 6.7e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NNECPOPP_01182 9.3e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NNECPOPP_01183 1.4e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NNECPOPP_01184 2.5e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NNECPOPP_01185 5.2e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNECPOPP_01187 1.6e-143 yiiD K acetyltransferase
NNECPOPP_01188 3.2e-255 cgeD M maturation of the outermost layer of the spore
NNECPOPP_01189 3.5e-38 cgeC
NNECPOPP_01190 1.5e-65 cgeA
NNECPOPP_01191 2.5e-183 cgeB S Spore maturation protein
NNECPOPP_01192 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NNECPOPP_01193 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NNECPOPP_01194 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NNECPOPP_01195 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NNECPOPP_01196 1.6e-70 ypoP K transcriptional
NNECPOPP_01197 4.5e-223 mepA V MATE efflux family protein
NNECPOPP_01198 5.5e-29 ypmT S Uncharacterized ympT
NNECPOPP_01199 8.5e-99 ypmS S protein conserved in bacteria
NNECPOPP_01200 4.8e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NNECPOPP_01201 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NNECPOPP_01202 3.4e-39 ypmP S Protein of unknown function (DUF2535)
NNECPOPP_01203 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NNECPOPP_01204 1.6e-185 pspF K Transcriptional regulator
NNECPOPP_01205 4.2e-110 hlyIII S protein, Hemolysin III
NNECPOPP_01206 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NNECPOPP_01207 5.1e-95 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NNECPOPP_01208 2.1e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NNECPOPP_01209 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NNECPOPP_01210 7.8e-114 ypjP S YpjP-like protein
NNECPOPP_01211 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NNECPOPP_01212 1.7e-75 yphP S Belongs to the UPF0403 family
NNECPOPP_01213 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NNECPOPP_01214 5.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
NNECPOPP_01215 1.1e-104 ypgQ S phosphohydrolase
NNECPOPP_01216 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NNECPOPP_01217 5.2e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NNECPOPP_01219 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NNECPOPP_01220 7.9e-31 cspD K Cold-shock protein
NNECPOPP_01221 3.8e-16 degR
NNECPOPP_01222 1.8e-30 S Protein of unknown function (DUF2564)
NNECPOPP_01223 2.6e-27 ypeQ S Zinc-finger
NNECPOPP_01224 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NNECPOPP_01225 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NNECPOPP_01226 1.3e-66 rnhA 3.1.26.4 L Ribonuclease
NNECPOPP_01228 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NNECPOPP_01229 2e-07
NNECPOPP_01230 2.9e-38 ypbS S Protein of unknown function (DUF2533)
NNECPOPP_01231 0.0 ypbR S Dynamin family
NNECPOPP_01233 1.9e-86 ypbQ S protein conserved in bacteria
NNECPOPP_01234 2.8e-207 bcsA Q Naringenin-chalcone synthase
NNECPOPP_01235 2.5e-226 pbuX F xanthine
NNECPOPP_01236 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NNECPOPP_01237 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NNECPOPP_01238 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NNECPOPP_01239 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NNECPOPP_01240 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NNECPOPP_01241 4.1e-184 ptxS K transcriptional
NNECPOPP_01242 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NNECPOPP_01243 8.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_01244 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NNECPOPP_01246 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NNECPOPP_01247 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NNECPOPP_01248 8.2e-91 ypsA S Belongs to the UPF0398 family
NNECPOPP_01249 3.3e-236 yprB L RNase_H superfamily
NNECPOPP_01250 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NNECPOPP_01251 1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NNECPOPP_01252 7.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
NNECPOPP_01253 1.2e-48 yppG S YppG-like protein
NNECPOPP_01255 3.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
NNECPOPP_01258 1.8e-186 yppC S Protein of unknown function (DUF2515)
NNECPOPP_01259 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NNECPOPP_01260 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NNECPOPP_01261 1.8e-92 ypoC
NNECPOPP_01262 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NNECPOPP_01263 1.3e-128 dnaD L DNA replication protein DnaD
NNECPOPP_01264 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NNECPOPP_01265 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NNECPOPP_01266 3.4e-80 ypmB S protein conserved in bacteria
NNECPOPP_01267 1.9e-22 ypmA S Protein of unknown function (DUF4264)
NNECPOPP_01268 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NNECPOPP_01269 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NNECPOPP_01270 4.4e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NNECPOPP_01271 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NNECPOPP_01272 4.8e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NNECPOPP_01273 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NNECPOPP_01274 4.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NNECPOPP_01275 6.9e-130 bshB1 S proteins, LmbE homologs
NNECPOPP_01276 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NNECPOPP_01277 4.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NNECPOPP_01278 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NNECPOPP_01279 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NNECPOPP_01280 6.1e-143 ypjB S sporulation protein
NNECPOPP_01281 7.6e-98 ypjA S membrane
NNECPOPP_01282 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NNECPOPP_01283 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NNECPOPP_01284 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NNECPOPP_01285 1e-75 ypiF S Protein of unknown function (DUF2487)
NNECPOPP_01286 2.8e-99 ypiB S Belongs to the UPF0302 family
NNECPOPP_01287 1e-232 S COG0457 FOG TPR repeat
NNECPOPP_01288 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NNECPOPP_01289 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NNECPOPP_01290 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NNECPOPP_01291 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NNECPOPP_01292 4.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NNECPOPP_01293 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NNECPOPP_01294 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NNECPOPP_01295 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NNECPOPP_01296 2.5e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NNECPOPP_01297 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NNECPOPP_01298 4.5e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NNECPOPP_01299 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NNECPOPP_01300 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NNECPOPP_01301 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NNECPOPP_01302 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NNECPOPP_01303 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NNECPOPP_01304 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NNECPOPP_01305 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NNECPOPP_01306 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NNECPOPP_01307 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNECPOPP_01308 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NNECPOPP_01309 9.3e-138 yphF
NNECPOPP_01310 1.6e-18 yphE S Protein of unknown function (DUF2768)
NNECPOPP_01311 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NNECPOPP_01312 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NNECPOPP_01313 7.9e-28 ypzH
NNECPOPP_01314 2.5e-161 seaA S YIEGIA protein
NNECPOPP_01315 1.3e-102 yphA
NNECPOPP_01316 1e-07 S YpzI-like protein
NNECPOPP_01317 2.6e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NNECPOPP_01318 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NNECPOPP_01319 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NNECPOPP_01320 1.8e-23 S Family of unknown function (DUF5359)
NNECPOPP_01321 9.2e-113 ypfA M Flagellar protein YcgR
NNECPOPP_01322 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NNECPOPP_01323 2.2e-152 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NNECPOPP_01324 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
NNECPOPP_01325 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NNECPOPP_01326 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NNECPOPP_01327 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NNECPOPP_01328 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NNECPOPP_01329 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NNECPOPP_01330 5e-75 ypbE M Lysin motif
NNECPOPP_01331 3.1e-99 ypbD S metal-dependent membrane protease
NNECPOPP_01332 9.2e-286 recQ 3.6.4.12 L DNA helicase
NNECPOPP_01333 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
NNECPOPP_01334 4.7e-41 fer C Ferredoxin
NNECPOPP_01335 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NNECPOPP_01336 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNECPOPP_01337 1.3e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NNECPOPP_01338 2.5e-195 rsiX
NNECPOPP_01339 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_01340 0.0 resE 2.7.13.3 T Histidine kinase
NNECPOPP_01341 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_01342 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NNECPOPP_01343 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NNECPOPP_01344 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NNECPOPP_01345 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NNECPOPP_01346 5.4e-87 spmB S Spore maturation protein
NNECPOPP_01347 3.5e-103 spmA S Spore maturation protein
NNECPOPP_01348 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NNECPOPP_01349 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NNECPOPP_01350 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NNECPOPP_01351 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NNECPOPP_01352 4.6e-91 ypuF S Domain of unknown function (DUF309)
NNECPOPP_01353 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNECPOPP_01354 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NNECPOPP_01355 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NNECPOPP_01356 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
NNECPOPP_01357 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NNECPOPP_01358 7.8e-55 ypuD
NNECPOPP_01359 2e-97 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NNECPOPP_01360 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NNECPOPP_01361 2.7e-13 S SNARE associated Golgi protein
NNECPOPP_01363 6.8e-08 eaeH M Domain of Unknown Function (DUF1259)
NNECPOPP_01365 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NNECPOPP_01366 3.6e-149 ypuA S Secreted protein
NNECPOPP_01367 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NNECPOPP_01368 4e-273 spoVAF EG Stage V sporulation protein AF
NNECPOPP_01369 1.4e-110 spoVAEA S stage V sporulation protein
NNECPOPP_01370 2.2e-57 spoVAEB S stage V sporulation protein
NNECPOPP_01371 9e-192 spoVAD I Stage V sporulation protein AD
NNECPOPP_01372 1.5e-77 spoVAC S stage V sporulation protein AC
NNECPOPP_01373 1e-67 spoVAB S Stage V sporulation protein AB
NNECPOPP_01374 9.6e-112 spoVAA S Stage V sporulation protein AA
NNECPOPP_01375 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNECPOPP_01376 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NNECPOPP_01377 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NNECPOPP_01378 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NNECPOPP_01379 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NNECPOPP_01380 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NNECPOPP_01381 2.6e-166 xerD L recombinase XerD
NNECPOPP_01382 1.4e-36 S Protein of unknown function (DUF4227)
NNECPOPP_01383 2.4e-80 fur P Belongs to the Fur family
NNECPOPP_01384 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NNECPOPP_01385 2.1e-29 yqkK
NNECPOPP_01386 5.5e-242 mleA 1.1.1.38 C malic enzyme
NNECPOPP_01387 3.1e-235 mleN C Na H antiporter
NNECPOPP_01388 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NNECPOPP_01389 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NNECPOPP_01390 4.5e-58 ansR K Transcriptional regulator
NNECPOPP_01391 6.6e-223 yqxK 3.6.4.12 L DNA helicase
NNECPOPP_01392 2.6e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NNECPOPP_01394 1.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NNECPOPP_01395 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NNECPOPP_01396 7.2e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NNECPOPP_01397 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NNECPOPP_01398 2.8e-54 yqkB S Belongs to the HesB IscA family
NNECPOPP_01399 1.1e-192 yqkA K GrpB protein
NNECPOPP_01400 1.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NNECPOPP_01401 3.6e-87 yqjY K acetyltransferase
NNECPOPP_01402 5.7e-50 S YolD-like protein
NNECPOPP_01403 1.3e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNECPOPP_01405 1.7e-224 yqjV G Major Facilitator Superfamily
NNECPOPP_01407 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNECPOPP_01408 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NNECPOPP_01409 7.1e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NNECPOPP_01410 5e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_01411 2e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NNECPOPP_01412 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNECPOPP_01413 0.0 rocB E arginine degradation protein
NNECPOPP_01414 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NNECPOPP_01415 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NNECPOPP_01416 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NNECPOPP_01417 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NNECPOPP_01418 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NNECPOPP_01419 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNECPOPP_01420 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNECPOPP_01421 4.5e-24 yqzJ
NNECPOPP_01422 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNECPOPP_01424 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
NNECPOPP_01425 1.6e-139 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNECPOPP_01426 2.3e-162 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNECPOPP_01427 3.9e-16 6.1.1.13, 6.2.1.50 IQ Phosphopantetheine attachment site
NNECPOPP_01428 1e-99 IQ reductase
NNECPOPP_01429 1.2e-238 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Histidine ammonia-lyase
NNECPOPP_01430 6.4e-154 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NNECPOPP_01431 2.1e-128 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NNECPOPP_01432 8e-142 yqjF S Uncharacterized conserved protein (COG2071)
NNECPOPP_01433 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NNECPOPP_01434 2.2e-290 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NNECPOPP_01435 4.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NNECPOPP_01437 2.3e-98 yqjB S protein conserved in bacteria
NNECPOPP_01438 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
NNECPOPP_01439 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NNECPOPP_01440 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NNECPOPP_01441 1.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NNECPOPP_01442 9.3e-77 yqiW S Belongs to the UPF0403 family
NNECPOPP_01443 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NNECPOPP_01444 1.4e-207 norA EGP Major facilitator Superfamily
NNECPOPP_01445 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NNECPOPP_01446 1.6e-225 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNECPOPP_01447 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNECPOPP_01448 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNECPOPP_01449 8.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNECPOPP_01450 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NNECPOPP_01451 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NNECPOPP_01452 3.9e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NNECPOPP_01453 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NNECPOPP_01454 4e-34 yqzF S Protein of unknown function (DUF2627)
NNECPOPP_01455 1.6e-163 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NNECPOPP_01456 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NNECPOPP_01457 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NNECPOPP_01458 6.7e-212 mmgC I acyl-CoA dehydrogenase
NNECPOPP_01459 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
NNECPOPP_01460 1.5e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
NNECPOPP_01461 2.9e-131 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NNECPOPP_01462 1.2e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NNECPOPP_01463 6e-27
NNECPOPP_01464 1.5e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NNECPOPP_01465 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NNECPOPP_01466 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NNECPOPP_01467 4.2e-306 recN L May be involved in recombinational repair of damaged DNA
NNECPOPP_01468 1.7e-78 argR K Regulates arginine biosynthesis genes
NNECPOPP_01469 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NNECPOPP_01470 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NNECPOPP_01471 2.2e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NNECPOPP_01472 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNECPOPP_01473 8.4e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNECPOPP_01474 1.3e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNECPOPP_01475 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NNECPOPP_01476 2.1e-67 yqhY S protein conserved in bacteria
NNECPOPP_01477 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NNECPOPP_01478 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NNECPOPP_01479 1.3e-90 spoIIIAH S SpoIIIAH-like protein
NNECPOPP_01480 1.9e-108 spoIIIAG S stage III sporulation protein AG
NNECPOPP_01481 9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NNECPOPP_01482 1.3e-197 spoIIIAE S stage III sporulation protein AE
NNECPOPP_01483 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NNECPOPP_01484 7.6e-29 spoIIIAC S stage III sporulation protein AC
NNECPOPP_01485 1.1e-84 spoIIIAB S Stage III sporulation protein
NNECPOPP_01486 4e-170 spoIIIAA S stage III sporulation protein AA
NNECPOPP_01487 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NNECPOPP_01488 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNECPOPP_01489 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NNECPOPP_01490 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NNECPOPP_01491 2.3e-93 yqhR S Conserved membrane protein YqhR
NNECPOPP_01492 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
NNECPOPP_01493 2.8e-48 yqhP
NNECPOPP_01494 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
NNECPOPP_01495 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NNECPOPP_01496 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NNECPOPP_01497 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NNECPOPP_01498 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NNECPOPP_01499 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NNECPOPP_01500 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NNECPOPP_01501 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NNECPOPP_01502 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NNECPOPP_01503 1.2e-24 sinI S Anti-repressor SinI
NNECPOPP_01504 1e-54 sinR K transcriptional
NNECPOPP_01505 2.5e-141 tasA S Cell division protein FtsN
NNECPOPP_01506 2.8e-57 sipW 3.4.21.89 U Signal peptidase
NNECPOPP_01507 3.7e-113 yqxM
NNECPOPP_01508 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NNECPOPP_01509 3.1e-26 yqzE S YqzE-like protein
NNECPOPP_01510 3.4e-43 S ComG operon protein 7
NNECPOPP_01511 1.3e-34 comGF U Putative Competence protein ComGF
NNECPOPP_01512 7.6e-58 comGE
NNECPOPP_01513 1.2e-68 gspH NU protein transport across the cell outer membrane
NNECPOPP_01514 1.4e-47 comGC U Required for transformation and DNA binding
NNECPOPP_01515 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
NNECPOPP_01516 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NNECPOPP_01519 1e-173 corA P Mg2 transporter protein
NNECPOPP_01520 7.5e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NNECPOPP_01521 2.7e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNECPOPP_01523 2.3e-63 yqgZ 1.20.4.1 P Belongs to the ArsC family
NNECPOPP_01524 4e-37 yqgY S Protein of unknown function (DUF2626)
NNECPOPP_01525 1.8e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NNECPOPP_01526 4.4e-22 yqgW S Protein of unknown function (DUF2759)
NNECPOPP_01527 6.9e-50 yqgV S Thiamine-binding protein
NNECPOPP_01528 6.1e-199 yqgU
NNECPOPP_01529 9.6e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NNECPOPP_01530 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NNECPOPP_01531 1.7e-179 glcK 2.7.1.2 G Glucokinase
NNECPOPP_01532 3.1e-33 yqgQ S Protein conserved in bacteria
NNECPOPP_01533 1.1e-265 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NNECPOPP_01534 2.5e-09 yqgO
NNECPOPP_01535 4.3e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NNECPOPP_01536 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NNECPOPP_01537 1.4e-196 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NNECPOPP_01539 9.2e-51 yqzD
NNECPOPP_01540 7e-75 yqzC S YceG-like family
NNECPOPP_01541 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNECPOPP_01542 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNECPOPP_01543 4.4e-158 pstA P Phosphate transport system permease
NNECPOPP_01544 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NNECPOPP_01545 2e-150 pstS P Phosphate
NNECPOPP_01546 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NNECPOPP_01547 2.5e-231 yqgE EGP Major facilitator superfamily
NNECPOPP_01548 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NNECPOPP_01549 4e-73 yqgC S protein conserved in bacteria
NNECPOPP_01550 3.9e-131 yqgB S Protein of unknown function (DUF1189)
NNECPOPP_01551 5.2e-47 yqfZ M LysM domain
NNECPOPP_01552 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NNECPOPP_01553 4.3e-62 yqfX S membrane
NNECPOPP_01554 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NNECPOPP_01555 1.9e-77 zur P Belongs to the Fur family
NNECPOPP_01556 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NNECPOPP_01557 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NNECPOPP_01558 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NNECPOPP_01559 5.9e-236 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NNECPOPP_01560 1.9e-13 yqfQ S YqfQ-like protein
NNECPOPP_01561 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NNECPOPP_01562 9.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NNECPOPP_01563 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
NNECPOPP_01564 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NNECPOPP_01565 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NNECPOPP_01566 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NNECPOPP_01567 4.5e-88 yaiI S Belongs to the UPF0178 family
NNECPOPP_01568 2.2e-148 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NNECPOPP_01569 4.5e-112 ccpN K CBS domain
NNECPOPP_01570 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NNECPOPP_01571 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NNECPOPP_01572 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
NNECPOPP_01573 8.4e-19 S YqzL-like protein
NNECPOPP_01574 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NNECPOPP_01575 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NNECPOPP_01576 3.5e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NNECPOPP_01577 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NNECPOPP_01578 0.0 yqfF S membrane-associated HD superfamily hydrolase
NNECPOPP_01580 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NNECPOPP_01581 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NNECPOPP_01582 2.7e-45 yqfC S sporulation protein YqfC
NNECPOPP_01583 6e-25 yqfB
NNECPOPP_01584 4.3e-122 yqfA S UPF0365 protein
NNECPOPP_01585 8.6e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NNECPOPP_01586 2.5e-61 yqeY S Yqey-like protein
NNECPOPP_01587 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NNECPOPP_01588 2.3e-157 yqeW P COG1283 Na phosphate symporter
NNECPOPP_01589 4.6e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NNECPOPP_01590 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NNECPOPP_01591 5.4e-175 prmA J Methylates ribosomal protein L11
NNECPOPP_01592 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NNECPOPP_01593 0.0 dnaK O Heat shock 70 kDa protein
NNECPOPP_01594 1.5e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NNECPOPP_01595 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NNECPOPP_01596 5.3e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NNECPOPP_01597 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NNECPOPP_01598 7.2e-53 yqxA S Protein of unknown function (DUF3679)
NNECPOPP_01599 3.4e-222 spoIIP M stage II sporulation protein P
NNECPOPP_01600 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NNECPOPP_01601 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NNECPOPP_01602 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NNECPOPP_01603 4.1e-15 S YqzM-like protein
NNECPOPP_01604 0.0 comEC S Competence protein ComEC
NNECPOPP_01605 1e-104 comEB 3.5.4.12 F ComE operon protein 2
NNECPOPP_01606 9.6e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NNECPOPP_01607 5.1e-145 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNECPOPP_01608 4.6e-137 yqeM Q Methyltransferase
NNECPOPP_01609 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NNECPOPP_01610 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NNECPOPP_01611 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NNECPOPP_01612 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NNECPOPP_01613 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNECPOPP_01614 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NNECPOPP_01615 5.3e-95 yqeG S hydrolase of the HAD superfamily
NNECPOPP_01617 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NNECPOPP_01618 5.4e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NNECPOPP_01619 1e-105 yqeD S SNARE associated Golgi protein
NNECPOPP_01620 2.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NNECPOPP_01621 2.3e-133 yqeB
NNECPOPP_01622 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NNECPOPP_01623 2.8e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNECPOPP_01624 1.8e-62 napB K helix_turn_helix multiple antibiotic resistance protein
NNECPOPP_01625 1.9e-219 yfjF U Belongs to the major facilitator superfamily
NNECPOPP_01626 9.3e-278 cisA2 L Recombinase
NNECPOPP_01627 1.3e-175 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NNECPOPP_01628 1.1e-112 yrkJ S membrane transporter protein
NNECPOPP_01629 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NNECPOPP_01630 4.9e-207 yrkH P Rhodanese Homology Domain
NNECPOPP_01631 1.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
NNECPOPP_01632 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
NNECPOPP_01633 7.8e-39 yrkD S protein conserved in bacteria
NNECPOPP_01634 3.8e-107 yrkC G Cupin domain
NNECPOPP_01635 9e-150 bltR K helix_turn_helix, mercury resistance
NNECPOPP_01636 3.9e-210 blt EGP Major facilitator Superfamily
NNECPOPP_01637 5.9e-82 bltD 2.3.1.57 K FR47-like protein
NNECPOPP_01638 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NNECPOPP_01639 3.9e-16 S YrzO-like protein
NNECPOPP_01640 2.7e-169 yrdR EG EamA-like transporter family
NNECPOPP_01641 1.5e-158 yrdQ K Transcriptional regulator
NNECPOPP_01642 1.5e-197 trkA P Oxidoreductase
NNECPOPP_01643 1.5e-153 czcD P COG1230 Co Zn Cd efflux system component
NNECPOPP_01644 1.3e-66 yodA S tautomerase
NNECPOPP_01645 5e-162 gltR K LysR substrate binding domain
NNECPOPP_01646 1.2e-225 brnQ E Component of the transport system for branched-chain amino acids
NNECPOPP_01647 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NNECPOPP_01648 2.8e-137 azlC E AzlC protein
NNECPOPP_01649 1.8e-78 bkdR K helix_turn_helix ASNC type
NNECPOPP_01650 1.2e-15 yrdF K ribonuclease inhibitor
NNECPOPP_01651 4.7e-227 cypA C Cytochrome P450
NNECPOPP_01652 2.5e-98 yrdC 3.5.1.19 Q Isochorismatase family
NNECPOPP_01653 4.4e-54 S Protein of unknown function (DUF2568)
NNECPOPP_01654 1.2e-88 yrdA S DinB family
NNECPOPP_01655 2.7e-165 aadK G Streptomycin adenylyltransferase
NNECPOPP_01656 6.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NNECPOPP_01657 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NNECPOPP_01658 1.8e-122 yrpD S Domain of unknown function, YrpD
NNECPOPP_01660 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NNECPOPP_01661 9.1e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_01662 2.9e-187 yrpG C Aldo/keto reductase family
NNECPOPP_01663 3.6e-225 yraO C Citrate transporter
NNECPOPP_01664 3.4e-163 yraN K Transcriptional regulator
NNECPOPP_01665 1.6e-205 yraM S PrpF protein
NNECPOPP_01666 2.3e-14 yraM S PrpF protein
NNECPOPP_01667 6.5e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NNECPOPP_01668 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNECPOPP_01669 5.3e-150 S Alpha beta hydrolase
NNECPOPP_01670 1.7e-60 T sh3 domain protein
NNECPOPP_01671 5.4e-61 T sh3 domain protein
NNECPOPP_01673 3.8e-66 E Glyoxalase-like domain
NNECPOPP_01674 1.5e-36 yraG
NNECPOPP_01675 6.4e-63 yraF M Spore coat protein
NNECPOPP_01676 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NNECPOPP_01677 2.2e-25 yraE
NNECPOPP_01678 1.1e-49 yraD M Spore coat protein
NNECPOPP_01679 4.3e-47 yraB K helix_turn_helix, mercury resistance
NNECPOPP_01680 3.5e-28 yphJ 4.1.1.44 S peroxiredoxin activity
NNECPOPP_01681 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
NNECPOPP_01682 1.5e-89 yhbO 1.11.1.6, 3.5.1.124 S protease
NNECPOPP_01683 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NNECPOPP_01684 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NNECPOPP_01685 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NNECPOPP_01686 9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NNECPOPP_01687 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
NNECPOPP_01688 0.0 levR K PTS system fructose IIA component
NNECPOPP_01689 3e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NNECPOPP_01690 1.1e-105 yrhP E LysE type translocator
NNECPOPP_01691 1.2e-149 yrhO K Archaeal transcriptional regulator TrmB
NNECPOPP_01692 7.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_01693 3.8e-151 rsiV S Protein of unknown function (DUF3298)
NNECPOPP_01694 0.0 yrhL I Acyltransferase family
NNECPOPP_01695 1.5e-46 yrhK S YrhK-like protein
NNECPOPP_01696 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NNECPOPP_01697 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NNECPOPP_01698 1.3e-96 yrhH Q methyltransferase
NNECPOPP_01701 3e-142 focA P Formate nitrite
NNECPOPP_01703 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
NNECPOPP_01704 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NNECPOPP_01705 1.4e-78 yrhD S Protein of unknown function (DUF1641)
NNECPOPP_01706 4.6e-35 yrhC S YrhC-like protein
NNECPOPP_01707 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NNECPOPP_01708 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NNECPOPP_01709 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NNECPOPP_01710 2.6e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NNECPOPP_01711 5e-25 yrzA S Protein of unknown function (DUF2536)
NNECPOPP_01712 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NNECPOPP_01713 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NNECPOPP_01714 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNECPOPP_01715 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NNECPOPP_01716 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NNECPOPP_01717 7.8e-174 yegQ O Peptidase U32
NNECPOPP_01718 6.6e-119 yrrM 2.1.1.104 S O-methyltransferase
NNECPOPP_01719 1.4e-182 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNECPOPP_01720 1.2e-45 yrzB S Belongs to the UPF0473 family
NNECPOPP_01721 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NNECPOPP_01722 1.7e-41 yrzL S Belongs to the UPF0297 family
NNECPOPP_01723 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NNECPOPP_01724 2.7e-170 yrrI S AI-2E family transporter
NNECPOPP_01725 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NNECPOPP_01726 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
NNECPOPP_01727 8e-109 gluC P ABC transporter
NNECPOPP_01728 7.6e-107 glnP P ABC transporter
NNECPOPP_01729 8e-08 S Protein of unknown function (DUF3918)
NNECPOPP_01730 9.8e-31 yrzR
NNECPOPP_01731 3.5e-82 yrrD S protein conserved in bacteria
NNECPOPP_01732 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NNECPOPP_01733 1.4e-15 S COG0457 FOG TPR repeat
NNECPOPP_01734 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NNECPOPP_01735 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
NNECPOPP_01736 1.2e-70 cymR K Transcriptional regulator
NNECPOPP_01737 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NNECPOPP_01738 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NNECPOPP_01739 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NNECPOPP_01740 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
NNECPOPP_01742 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
NNECPOPP_01743 8.5e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NNECPOPP_01744 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NNECPOPP_01745 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NNECPOPP_01746 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NNECPOPP_01747 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NNECPOPP_01748 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NNECPOPP_01749 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NNECPOPP_01750 1.6e-48 yrzD S Post-transcriptional regulator
NNECPOPP_01751 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNECPOPP_01752 1.7e-111 yrbG S membrane
NNECPOPP_01753 3.8e-73 yrzE S Protein of unknown function (DUF3792)
NNECPOPP_01754 1.1e-38 yajC U Preprotein translocase subunit YajC
NNECPOPP_01755 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NNECPOPP_01756 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NNECPOPP_01757 1e-17 yrzS S Protein of unknown function (DUF2905)
NNECPOPP_01758 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NNECPOPP_01759 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NNECPOPP_01760 4.8e-93 bofC S BofC C-terminal domain
NNECPOPP_01761 5.3e-253 csbX EGP Major facilitator Superfamily
NNECPOPP_01762 1.4e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NNECPOPP_01763 1.9e-118 yrzF T serine threonine protein kinase
NNECPOPP_01765 3.1e-51 S Family of unknown function (DUF5412)
NNECPOPP_01766 1.8e-262 alsT E Sodium alanine symporter
NNECPOPP_01767 2.7e-126 yebC K transcriptional regulatory protein
NNECPOPP_01768 1.7e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNECPOPP_01769 8.3e-157 safA M spore coat assembly protein SafA
NNECPOPP_01770 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NNECPOPP_01771 2.7e-160 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NNECPOPP_01772 2.3e-306 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NNECPOPP_01773 3.7e-229 nifS 2.8.1.7 E Cysteine desulfurase
NNECPOPP_01774 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NNECPOPP_01775 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
NNECPOPP_01776 6.3e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NNECPOPP_01777 1.6e-230 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NNECPOPP_01778 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NNECPOPP_01779 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NNECPOPP_01780 4.1e-56 ysxB J ribosomal protein
NNECPOPP_01781 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NNECPOPP_01782 9.2e-161 spoIVFB S Stage IV sporulation protein
NNECPOPP_01783 2.1e-143 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NNECPOPP_01784 4.7e-143 minD D Belongs to the ParA family
NNECPOPP_01785 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NNECPOPP_01786 1.4e-84 mreD M shape-determining protein
NNECPOPP_01787 1.1e-156 mreC M Involved in formation and maintenance of cell shape
NNECPOPP_01788 1.8e-184 mreB D Rod shape-determining protein MreB
NNECPOPP_01789 5.9e-126 radC E Belongs to the UPF0758 family
NNECPOPP_01790 2.8e-102 maf D septum formation protein Maf
NNECPOPP_01791 7.8e-164 spoIIB S Sporulation related domain
NNECPOPP_01792 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NNECPOPP_01793 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NNECPOPP_01794 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NNECPOPP_01795 1.6e-25
NNECPOPP_01796 1.9e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NNECPOPP_01797 2.1e-220 spoVID M stage VI sporulation protein D
NNECPOPP_01798 7.3e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NNECPOPP_01799 3.6e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NNECPOPP_01800 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NNECPOPP_01801 9.6e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NNECPOPP_01802 3.6e-146 hemX O cytochrome C
NNECPOPP_01803 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NNECPOPP_01804 3.2e-89 ysxD
NNECPOPP_01805 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NNECPOPP_01806 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NNECPOPP_01807 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NNECPOPP_01808 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NNECPOPP_01809 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NNECPOPP_01810 1.1e-186 ysoA H Tetratricopeptide repeat
NNECPOPP_01811 9.9e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NNECPOPP_01812 6.3e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NNECPOPP_01813 3.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NNECPOPP_01814 2e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NNECPOPP_01815 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NNECPOPP_01816 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NNECPOPP_01817 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NNECPOPP_01819 9.3e-80 ysnE K acetyltransferase
NNECPOPP_01820 2.7e-117 ysnF S protein conserved in bacteria
NNECPOPP_01822 4.1e-92 ysnB S Phosphoesterase
NNECPOPP_01823 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NNECPOPP_01824 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NNECPOPP_01825 2.9e-196 gerM S COG5401 Spore germination protein
NNECPOPP_01826 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NNECPOPP_01827 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NNECPOPP_01828 3.3e-30 gerE K Transcriptional regulator
NNECPOPP_01829 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NNECPOPP_01830 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NNECPOPP_01831 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NNECPOPP_01832 2.4e-107 sdhC C succinate dehydrogenase
NNECPOPP_01833 1.2e-79 yslB S Protein of unknown function (DUF2507)
NNECPOPP_01834 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NNECPOPP_01835 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NNECPOPP_01836 2e-52 trxA O Belongs to the thioredoxin family
NNECPOPP_01837 1.2e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NNECPOPP_01838 4.2e-178 etfA C Electron transfer flavoprotein
NNECPOPP_01839 1e-134 etfB C Electron transfer flavoprotein
NNECPOPP_01840 2.7e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NNECPOPP_01841 2.3e-99 fadR K Transcriptional regulator
NNECPOPP_01842 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NNECPOPP_01843 7.3e-68 yshE S membrane
NNECPOPP_01844 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NNECPOPP_01845 0.0 polX L COG1796 DNA polymerase IV (family X)
NNECPOPP_01846 1.3e-85 cvpA S membrane protein, required for colicin V production
NNECPOPP_01847 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NNECPOPP_01848 1.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNECPOPP_01849 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNECPOPP_01850 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NNECPOPP_01851 1e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNECPOPP_01852 7.6e-32 sspI S Belongs to the SspI family
NNECPOPP_01853 9.2e-206 ysfB KT regulator
NNECPOPP_01854 7.5e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
NNECPOPP_01855 8.1e-257 glcF C Glycolate oxidase
NNECPOPP_01856 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NNECPOPP_01857 0.0 cstA T Carbon starvation protein
NNECPOPP_01858 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NNECPOPP_01859 2.9e-143 araQ G transport system permease
NNECPOPP_01860 1.4e-167 araP G carbohydrate transport
NNECPOPP_01861 6.2e-254 araN G carbohydrate transport
NNECPOPP_01862 3.4e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NNECPOPP_01863 1.7e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NNECPOPP_01864 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NNECPOPP_01865 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NNECPOPP_01866 1.7e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NNECPOPP_01867 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NNECPOPP_01868 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
NNECPOPP_01869 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NNECPOPP_01870 7.5e-45 ysdA S Membrane
NNECPOPP_01871 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NNECPOPP_01872 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NNECPOPP_01873 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NNECPOPP_01875 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NNECPOPP_01876 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NNECPOPP_01877 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
NNECPOPP_01878 0.0 lytS 2.7.13.3 T Histidine kinase
NNECPOPP_01879 1.5e-149 ysaA S HAD-hyrolase-like
NNECPOPP_01880 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNECPOPP_01881 1.9e-158 ytxC S YtxC-like family
NNECPOPP_01882 1.1e-110 ytxB S SNARE associated Golgi protein
NNECPOPP_01883 3e-173 dnaI L Primosomal protein DnaI
NNECPOPP_01884 2.9e-265 dnaB L Membrane attachment protein
NNECPOPP_01885 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NNECPOPP_01886 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NNECPOPP_01887 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNECPOPP_01888 9.9e-67 ytcD K Transcriptional regulator
NNECPOPP_01889 3.5e-203 ytbD EGP Major facilitator Superfamily
NNECPOPP_01890 8.9e-161 ytbE S reductase
NNECPOPP_01891 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NNECPOPP_01892 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NNECPOPP_01893 8.6e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NNECPOPP_01894 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NNECPOPP_01895 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NNECPOPP_01896 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_01897 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NNECPOPP_01898 4.1e-242 icd 1.1.1.42 C isocitrate
NNECPOPP_01899 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NNECPOPP_01900 4.7e-71 yeaL S membrane
NNECPOPP_01901 6.4e-191 ytvI S sporulation integral membrane protein YtvI
NNECPOPP_01902 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NNECPOPP_01903 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NNECPOPP_01904 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NNECPOPP_01905 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NNECPOPP_01906 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NNECPOPP_01907 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NNECPOPP_01908 0.0 dnaE 2.7.7.7 L DNA polymerase
NNECPOPP_01909 3.2e-56 ytrH S Sporulation protein YtrH
NNECPOPP_01910 8.2e-69 ytrI
NNECPOPP_01911 9.2e-29
NNECPOPP_01912 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NNECPOPP_01913 2.4e-47 ytpI S YtpI-like protein
NNECPOPP_01914 8e-241 ytoI K transcriptional regulator containing CBS domains
NNECPOPP_01915 1.2e-158 ytnM S membrane transporter protein
NNECPOPP_01916 2.4e-234 ytnL 3.5.1.47 E hydrolase activity
NNECPOPP_01917 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NNECPOPP_01918 2e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNECPOPP_01919 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
NNECPOPP_01920 4e-184 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNECPOPP_01921 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NNECPOPP_01922 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
NNECPOPP_01923 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NNECPOPP_01924 4.4e-149 tcyK M Bacterial periplasmic substrate-binding proteins
NNECPOPP_01925 1.1e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
NNECPOPP_01926 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
NNECPOPP_01927 4.2e-172 ytlI K LysR substrate binding domain
NNECPOPP_01928 1.7e-130 ytkL S Belongs to the UPF0173 family
NNECPOPP_01929 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_01931 4.4e-266 argH 4.3.2.1 E argininosuccinate lyase
NNECPOPP_01932 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNECPOPP_01933 6.8e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NNECPOPP_01934 8.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNECPOPP_01935 2.7e-164 ytxK 2.1.1.72 L DNA methylase
NNECPOPP_01936 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNECPOPP_01937 8.7e-70 ytfJ S Sporulation protein YtfJ
NNECPOPP_01938 5.6e-116 ytfI S Protein of unknown function (DUF2953)
NNECPOPP_01939 3.2e-86 yteJ S RDD family
NNECPOPP_01940 1.8e-179 sppA OU signal peptide peptidase SppA
NNECPOPP_01941 2.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNECPOPP_01942 0.0 ytcJ S amidohydrolase
NNECPOPP_01943 1.7e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NNECPOPP_01944 2e-29 sspB S spore protein
NNECPOPP_01945 1.7e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NNECPOPP_01946 2.7e-208 iscS2 2.8.1.7 E Cysteine desulfurase
NNECPOPP_01947 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
NNECPOPP_01948 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NNECPOPP_01949 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NNECPOPP_01950 1e-108 yttP K Transcriptional regulator
NNECPOPP_01951 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NNECPOPP_01952 2e-308 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NNECPOPP_01953 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NNECPOPP_01955 8.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNECPOPP_01956 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NNECPOPP_01957 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NNECPOPP_01958 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NNECPOPP_01959 5.4e-225 acuC BQ histone deacetylase
NNECPOPP_01960 1.4e-125 motS N Flagellar motor protein
NNECPOPP_01961 2.1e-146 motA N flagellar motor
NNECPOPP_01962 1.7e-182 ccpA K catabolite control protein A
NNECPOPP_01963 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NNECPOPP_01964 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
NNECPOPP_01965 6.6e-17 ytxH S COG4980 Gas vesicle protein
NNECPOPP_01966 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NNECPOPP_01967 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NNECPOPP_01968 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NNECPOPP_01969 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNECPOPP_01970 2.2e-148 ytpQ S Belongs to the UPF0354 family
NNECPOPP_01971 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NNECPOPP_01972 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NNECPOPP_01973 1.2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NNECPOPP_01974 2.2e-51 ytzB S small secreted protein
NNECPOPP_01975 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NNECPOPP_01976 1.6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NNECPOPP_01977 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NNECPOPP_01978 2e-45 ytzH S YtzH-like protein
NNECPOPP_01979 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NNECPOPP_01980 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NNECPOPP_01981 8.6e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NNECPOPP_01982 8.5e-165 ytlQ
NNECPOPP_01983 2.6e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NNECPOPP_01984 9.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NNECPOPP_01985 1.7e-270 pepV 3.5.1.18 E Dipeptidase
NNECPOPP_01986 2.1e-225 pbuO S permease
NNECPOPP_01987 2.7e-200 ythQ U Bacterial ABC transporter protein EcsB
NNECPOPP_01988 4.8e-131 ythP V ABC transporter
NNECPOPP_01989 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NNECPOPP_01990 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NNECPOPP_01991 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNECPOPP_01992 8.2e-232 ytfP S HI0933-like protein
NNECPOPP_01993 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NNECPOPP_01994 3.1e-26 yteV S Sporulation protein Cse60
NNECPOPP_01995 5e-114 yteU S Integral membrane protein
NNECPOPP_01996 4.1e-247 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NNECPOPP_01997 1.5e-71 yteS G transport
NNECPOPP_01998 1.1e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NNECPOPP_01999 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NNECPOPP_02000 0.0 ytdP K Transcriptional regulator
NNECPOPP_02001 4.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NNECPOPP_02002 1.3e-143 ytcP G COG0395 ABC-type sugar transport system, permease component
NNECPOPP_02003 1.4e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NNECPOPP_02004 4.1e-220 bioI 1.14.14.46 C Cytochrome P450
NNECPOPP_02005 3.5e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NNECPOPP_02006 2.2e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NNECPOPP_02007 1.9e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NNECPOPP_02008 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NNECPOPP_02009 5.2e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NNECPOPP_02010 1.6e-171 ytaP S Acetyl xylan esterase (AXE1)
NNECPOPP_02011 1.5e-189 msmR K Transcriptional regulator
NNECPOPP_02012 4e-245 msmE G Bacterial extracellular solute-binding protein
NNECPOPP_02013 6.2e-168 amyD P ABC transporter
NNECPOPP_02014 2.2e-143 amyC P ABC transporter (permease)
NNECPOPP_02015 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NNECPOPP_02016 2.1e-51 ytwF P Sulfurtransferase
NNECPOPP_02017 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NNECPOPP_02018 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NNECPOPP_02019 2.4e-139 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NNECPOPP_02020 5.6e-209 yttB EGP Major facilitator Superfamily
NNECPOPP_02021 2.5e-42 yttA 2.7.13.3 S Pfam Transposase IS66
NNECPOPP_02022 0.0 bceB V ABC transporter (permease)
NNECPOPP_02023 1.1e-138 bceA V ABC transporter, ATP-binding protein
NNECPOPP_02024 1.8e-184 T PhoQ Sensor
NNECPOPP_02025 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_02026 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NNECPOPP_02027 1.6e-126 ytrE V ABC transporter, ATP-binding protein
NNECPOPP_02028 1.6e-148
NNECPOPP_02029 2.8e-158 P ABC-2 family transporter protein
NNECPOPP_02030 4.2e-161 ytrB P abc transporter atp-binding protein
NNECPOPP_02031 5.1e-66 ytrA K GntR family transcriptional regulator
NNECPOPP_02033 1.5e-40 ytzC S Protein of unknown function (DUF2524)
NNECPOPP_02034 5.2e-189 yhcC S Fe-S oxidoreductase
NNECPOPP_02035 9.7e-106 ytqB J Putative rRNA methylase
NNECPOPP_02036 1.3e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NNECPOPP_02037 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NNECPOPP_02038 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NNECPOPP_02039 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NNECPOPP_02040 0.0 asnB 6.3.5.4 E Asparagine synthase
NNECPOPP_02041 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NNECPOPP_02042 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NNECPOPP_02043 1.6e-38 ytmB S Protein of unknown function (DUF2584)
NNECPOPP_02044 2.7e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NNECPOPP_02045 4e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NNECPOPP_02046 1.4e-144 ytlC P ABC transporter
NNECPOPP_02047 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NNECPOPP_02048 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NNECPOPP_02049 6e-62 ytkC S Bacteriophage holin family
NNECPOPP_02050 2.1e-76 dps P Belongs to the Dps family
NNECPOPP_02052 1.5e-71 ytkA S YtkA-like
NNECPOPP_02053 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NNECPOPP_02054 1.1e-101 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NNECPOPP_02055 3.6e-41 rpmE2 J Ribosomal protein L31
NNECPOPP_02056 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
NNECPOPP_02057 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NNECPOPP_02058 1.1e-24 S Domain of Unknown Function (DUF1540)
NNECPOPP_02059 2.3e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NNECPOPP_02060 4.4e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NNECPOPP_02061 4.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NNECPOPP_02062 6.7e-170 troA P Belongs to the bacterial solute-binding protein 9 family
NNECPOPP_02063 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NNECPOPP_02064 3.2e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNECPOPP_02065 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NNECPOPP_02066 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NNECPOPP_02067 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NNECPOPP_02068 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
NNECPOPP_02069 9.7e-132 dksA T COG1734 DnaK suppressor protein
NNECPOPP_02070 1.4e-150 galU 2.7.7.9 M Nucleotidyl transferase
NNECPOPP_02071 3.7e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNECPOPP_02072 4.8e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NNECPOPP_02073 6.7e-234 ytcC M Glycosyltransferase Family 4
NNECPOPP_02075 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
NNECPOPP_02076 1.8e-217 cotSA M Glycosyl transferases group 1
NNECPOPP_02077 1.3e-204 cotI S Spore coat protein
NNECPOPP_02078 3.8e-76 tspO T membrane
NNECPOPP_02079 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NNECPOPP_02080 1.2e-285 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NNECPOPP_02081 2.2e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NNECPOPP_02082 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NNECPOPP_02083 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NNECPOPP_02092 7.8e-08
NNECPOPP_02093 1.3e-09
NNECPOPP_02100 2e-08
NNECPOPP_02105 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NNECPOPP_02106 3.4e-94 M1-753 M FR47-like protein
NNECPOPP_02107 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
NNECPOPP_02108 2e-73 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NNECPOPP_02109 8.7e-84 yuaE S DinB superfamily
NNECPOPP_02110 7.9e-108 yuaD
NNECPOPP_02111 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NNECPOPP_02112 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NNECPOPP_02113 1.4e-95 yuaC K Belongs to the GbsR family
NNECPOPP_02114 2.2e-91 yuaB
NNECPOPP_02115 2.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
NNECPOPP_02116 3.9e-235 ktrB P Potassium
NNECPOPP_02117 1e-38 yiaA S yiaA/B two helix domain
NNECPOPP_02118 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNECPOPP_02119 5.8e-275 yubD P Major Facilitator Superfamily
NNECPOPP_02120 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NNECPOPP_02122 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NNECPOPP_02123 1.8e-196 yubA S transporter activity
NNECPOPP_02124 5.7e-183 ygjR S Oxidoreductase
NNECPOPP_02125 1.1e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NNECPOPP_02126 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NNECPOPP_02127 1.5e-272 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NNECPOPP_02128 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NNECPOPP_02129 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NNECPOPP_02130 7.3e-238 mcpA NT chemotaxis protein
NNECPOPP_02131 3.2e-294 mcpA NT chemotaxis protein
NNECPOPP_02132 3.3e-222 mcpA NT chemotaxis protein
NNECPOPP_02133 4.6e-224 mcpA NT chemotaxis protein
NNECPOPP_02134 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NNECPOPP_02135 6e-36
NNECPOPP_02136 2.1e-72 yugU S Uncharacterised protein family UPF0047
NNECPOPP_02137 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NNECPOPP_02138 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NNECPOPP_02139 1.4e-116 yugP S Zn-dependent protease
NNECPOPP_02140 2.3e-38
NNECPOPP_02141 1.1e-53 mstX S Membrane-integrating protein Mistic
NNECPOPP_02142 8.2e-182 yugO P COG1226 Kef-type K transport systems
NNECPOPP_02143 1.4e-71 yugN S YugN-like family
NNECPOPP_02145 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NNECPOPP_02146 3.1e-228 yugK C Dehydrogenase
NNECPOPP_02147 2.6e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NNECPOPP_02148 1.1e-34 yuzA S Domain of unknown function (DUF378)
NNECPOPP_02149 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NNECPOPP_02150 6.2e-199 yugH 2.6.1.1 E Aminotransferase
NNECPOPP_02151 1.6e-85 alaR K Transcriptional regulator
NNECPOPP_02152 4.9e-156 yugF I Hydrolase
NNECPOPP_02153 4.6e-39 yugE S Domain of unknown function (DUF1871)
NNECPOPP_02154 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NNECPOPP_02155 4.6e-233 T PhoQ Sensor
NNECPOPP_02156 1.8e-68 kapB G Kinase associated protein B
NNECPOPP_02157 1.9e-115 kapD L the KinA pathway to sporulation
NNECPOPP_02159 2.1e-183 yuxJ EGP Major facilitator Superfamily
NNECPOPP_02160 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NNECPOPP_02161 6.3e-75 yuxK S protein conserved in bacteria
NNECPOPP_02162 6.3e-78 yufK S Family of unknown function (DUF5366)
NNECPOPP_02163 6.4e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NNECPOPP_02164 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NNECPOPP_02165 7.2e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NNECPOPP_02166 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NNECPOPP_02167 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NNECPOPP_02168 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NNECPOPP_02169 8.2e-233 maeN C COG3493 Na citrate symporter
NNECPOPP_02170 3.2e-14
NNECPOPP_02171 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NNECPOPP_02172 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNECPOPP_02173 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNECPOPP_02174 2.7e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNECPOPP_02175 2.4e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNECPOPP_02176 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNECPOPP_02177 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NNECPOPP_02178 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NNECPOPP_02179 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNECPOPP_02180 1.3e-262 comP 2.7.13.3 T Histidine kinase
NNECPOPP_02182 1.4e-141 comQ H Belongs to the FPP GGPP synthase family
NNECPOPP_02184 3.8e-23 yuzC
NNECPOPP_02185 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NNECPOPP_02186 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NNECPOPP_02187 2.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
NNECPOPP_02188 2.3e-66 yueI S Protein of unknown function (DUF1694)
NNECPOPP_02189 7.4e-39 yueH S YueH-like protein
NNECPOPP_02190 2.1e-32 yueG S Spore germination protein gerPA/gerPF
NNECPOPP_02191 3.2e-190 yueF S transporter activity
NNECPOPP_02192 1.8e-68 S Protein of unknown function (DUF2283)
NNECPOPP_02193 2.9e-24 S Protein of unknown function (DUF2642)
NNECPOPP_02194 4.8e-96 yueE S phosphohydrolase
NNECPOPP_02195 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_02196 6.6e-65 yueC S Family of unknown function (DUF5383)
NNECPOPP_02197 0.0 esaA S type VII secretion protein EsaA
NNECPOPP_02198 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NNECPOPP_02199 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NNECPOPP_02200 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NNECPOPP_02201 2.8e-45 esxA S Belongs to the WXG100 family
NNECPOPP_02202 5.5e-228 yukF QT Transcriptional regulator
NNECPOPP_02203 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NNECPOPP_02204 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NNECPOPP_02205 5e-36 mbtH S MbtH-like protein
NNECPOPP_02206 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_02207 8.9e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NNECPOPP_02208 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NNECPOPP_02209 3.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
NNECPOPP_02210 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_02211 1.5e-166 besA S Putative esterase
NNECPOPP_02212 4.9e-121 yuiH S Oxidoreductase molybdopterin binding domain
NNECPOPP_02213 3.3e-93 bioY S Biotin biosynthesis protein
NNECPOPP_02214 3.9e-211 yuiF S antiporter
NNECPOPP_02215 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NNECPOPP_02216 2e-77 yuiD S protein conserved in bacteria
NNECPOPP_02217 1e-116 yuiC S protein conserved in bacteria
NNECPOPP_02218 3.2e-26 yuiB S Putative membrane protein
NNECPOPP_02219 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NNECPOPP_02220 3.9e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
NNECPOPP_02222 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNECPOPP_02223 7.2e-115 paiB K Putative FMN-binding domain
NNECPOPP_02224 1.4e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNECPOPP_02225 3.7e-63 erpA S Belongs to the HesB IscA family
NNECPOPP_02226 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NNECPOPP_02227 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNECPOPP_02228 3.2e-39 yuzB S Belongs to the UPF0349 family
NNECPOPP_02229 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NNECPOPP_02230 1.1e-55 yuzD S protein conserved in bacteria
NNECPOPP_02231 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NNECPOPP_02232 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NNECPOPP_02233 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NNECPOPP_02234 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NNECPOPP_02235 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
NNECPOPP_02236 2e-199 yutH S Spore coat protein
NNECPOPP_02237 3.3e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NNECPOPP_02238 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NNECPOPP_02239 7.3e-74 yutE S Protein of unknown function DUF86
NNECPOPP_02240 9.7e-48 yutD S protein conserved in bacteria
NNECPOPP_02241 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNECPOPP_02242 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NNECPOPP_02243 1.3e-195 lytH M Peptidase, M23
NNECPOPP_02244 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
NNECPOPP_02245 4.8e-48 yunC S Domain of unknown function (DUF1805)
NNECPOPP_02246 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NNECPOPP_02247 2e-141 yunE S membrane transporter protein
NNECPOPP_02248 4.3e-171 yunF S Protein of unknown function DUF72
NNECPOPP_02249 2.8e-60 yunG
NNECPOPP_02250 4.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NNECPOPP_02251 6.4e-301 pucR QT COG2508 Regulator of polyketide synthase expression
NNECPOPP_02252 2.5e-234 pbuX F Permease family
NNECPOPP_02253 2.4e-221 pbuX F xanthine
NNECPOPP_02254 6.4e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NNECPOPP_02255 2.1e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NNECPOPP_02256 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NNECPOPP_02257 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NNECPOPP_02258 9.8e-144 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NNECPOPP_02259 1.7e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NNECPOPP_02260 1.6e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NNECPOPP_02262 5.1e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NNECPOPP_02263 6.4e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NNECPOPP_02264 2e-168 bsn L Ribonuclease
NNECPOPP_02265 1.2e-205 msmX P Belongs to the ABC transporter superfamily
NNECPOPP_02266 3.3e-135 yurK K UTRA
NNECPOPP_02267 2.2e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NNECPOPP_02268 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NNECPOPP_02269 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
NNECPOPP_02270 9.4e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NNECPOPP_02271 5.7e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NNECPOPP_02272 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NNECPOPP_02273 6.9e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NNECPOPP_02275 1e-41
NNECPOPP_02276 3.5e-271 sufB O FeS cluster assembly
NNECPOPP_02277 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NNECPOPP_02278 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NNECPOPP_02279 2.4e-245 sufD O assembly protein SufD
NNECPOPP_02280 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NNECPOPP_02281 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NNECPOPP_02282 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
NNECPOPP_02283 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NNECPOPP_02284 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNECPOPP_02285 2.4e-56 yusD S SCP-2 sterol transfer family
NNECPOPP_02286 1.2e-54 traF CO Thioredoxin
NNECPOPP_02287 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NNECPOPP_02288 1.1e-39 yusG S Protein of unknown function (DUF2553)
NNECPOPP_02289 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NNECPOPP_02290 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NNECPOPP_02291 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NNECPOPP_02292 1.2e-216 fadA 2.3.1.16 I Belongs to the thiolase family
NNECPOPP_02293 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NNECPOPP_02294 8.1e-09 S YuzL-like protein
NNECPOPP_02295 1.9e-164 fadM E Proline dehydrogenase
NNECPOPP_02296 5.1e-40
NNECPOPP_02297 5.4e-53 yusN M Coat F domain
NNECPOPP_02298 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NNECPOPP_02299 9.4e-292 yusP P Major facilitator superfamily
NNECPOPP_02300 2.7e-64 yusQ S Tautomerase enzyme
NNECPOPP_02301 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_02302 1.1e-158 yusT K LysR substrate binding domain
NNECPOPP_02303 3.8e-47 yusU S Protein of unknown function (DUF2573)
NNECPOPP_02304 1e-153 yusV 3.6.3.34 HP ABC transporter
NNECPOPP_02305 2.5e-66 S YusW-like protein
NNECPOPP_02306 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
NNECPOPP_02307 7.6e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_02308 4.7e-79 dps P Ferritin-like domain
NNECPOPP_02309 1.2e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNECPOPP_02310 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_02311 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NNECPOPP_02312 4.3e-158 yuxN K Transcriptional regulator
NNECPOPP_02313 9.6e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NNECPOPP_02314 3.9e-24 S Protein of unknown function (DUF3970)
NNECPOPP_02315 1.4e-246 gerAA EG Spore germination protein
NNECPOPP_02316 1.3e-196 gerAB E Spore germination protein
NNECPOPP_02317 1.2e-184 gerAC S Spore germination B3/ GerAC like, C-terminal
NNECPOPP_02318 7.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNECPOPP_02319 1e-185 vraS 2.7.13.3 T Histidine kinase
NNECPOPP_02320 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NNECPOPP_02321 9.3e-129 liaG S Putative adhesin
NNECPOPP_02322 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NNECPOPP_02323 6.2e-61 liaI S membrane
NNECPOPP_02324 1.4e-226 yvqJ EGP Major facilitator Superfamily
NNECPOPP_02325 3.6e-100 yvqK 2.5.1.17 S Adenosyltransferase
NNECPOPP_02326 1.3e-243 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NNECPOPP_02327 1.7e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_02328 5e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NNECPOPP_02329 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_02330 5.8e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NNECPOPP_02331 0.0 T PhoQ Sensor
NNECPOPP_02332 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_02333 7.2e-23
NNECPOPP_02334 2.1e-97 yvrI K RNA polymerase
NNECPOPP_02335 2.4e-19 S YvrJ protein family
NNECPOPP_02336 1.2e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
NNECPOPP_02337 1.3e-64 yvrL S Regulatory protein YrvL
NNECPOPP_02338 8.9e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NNECPOPP_02339 1.6e-123 macB V ABC transporter, ATP-binding protein
NNECPOPP_02340 2.2e-173 M Efflux transporter rnd family, mfp subunit
NNECPOPP_02341 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NNECPOPP_02342 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_02343 6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_02344 1.5e-177 fhuD P ABC transporter
NNECPOPP_02345 1.4e-235 yvsH E Arginine ornithine antiporter
NNECPOPP_02346 6.5e-16 S Small spore protein J (Spore_SspJ)
NNECPOPP_02347 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NNECPOPP_02348 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NNECPOPP_02349 7.8e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NNECPOPP_02350 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NNECPOPP_02351 6.9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NNECPOPP_02352 1.1e-155 yvgN S reductase
NNECPOPP_02353 5.4e-86 yvgO
NNECPOPP_02354 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NNECPOPP_02355 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NNECPOPP_02356 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NNECPOPP_02357 0.0 helD 3.6.4.12 L DNA helicase
NNECPOPP_02359 1.6e-106 yvgT S membrane
NNECPOPP_02360 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NNECPOPP_02361 6.1e-104 bdbD O Thioredoxin
NNECPOPP_02362 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NNECPOPP_02363 0.0 copA 3.6.3.54 P P-type ATPase
NNECPOPP_02364 1.5e-29 copZ P Copper resistance protein CopZ
NNECPOPP_02365 2.2e-48 csoR S transcriptional
NNECPOPP_02366 1.2e-194 yvaA 1.1.1.371 S Oxidoreductase
NNECPOPP_02367 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NNECPOPP_02368 0.0 yvaC S Fusaric acid resistance protein-like
NNECPOPP_02369 5.7e-73 yvaD S Family of unknown function (DUF5360)
NNECPOPP_02370 6.3e-55 yvaE P Small Multidrug Resistance protein
NNECPOPP_02371 4.6e-100 K Bacterial regulatory proteins, tetR family
NNECPOPP_02372 3.4e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_02374 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NNECPOPP_02375 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NNECPOPP_02376 1.6e-142 est 3.1.1.1 S Carboxylesterase
NNECPOPP_02377 2.4e-23 secG U Preprotein translocase subunit SecG
NNECPOPP_02378 2.2e-150 yvaM S Serine aminopeptidase, S33
NNECPOPP_02379 7.5e-36 yvzC K Transcriptional
NNECPOPP_02380 4e-69 K transcriptional
NNECPOPP_02381 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
NNECPOPP_02382 2.2e-54 yodB K transcriptional
NNECPOPP_02383 4.5e-204 NT chemotaxis protein
NNECPOPP_02384 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NNECPOPP_02385 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NNECPOPP_02386 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NNECPOPP_02387 1.1e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NNECPOPP_02388 3.3e-60 yvbF K Belongs to the GbsR family
NNECPOPP_02389 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NNECPOPP_02390 1.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NNECPOPP_02391 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NNECPOPP_02392 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NNECPOPP_02393 3.5e-97 yvbF K Belongs to the GbsR family
NNECPOPP_02394 6.4e-103 yvbG U UPF0056 membrane protein
NNECPOPP_02395 8.6e-113 yvbH S YvbH-like oligomerisation region
NNECPOPP_02396 3.6e-123 exoY M Membrane
NNECPOPP_02397 0.0 tcaA S response to antibiotic
NNECPOPP_02398 1.3e-81 yvbK 3.1.3.25 K acetyltransferase
NNECPOPP_02399 2.7e-174 EGP Major facilitator Superfamily
NNECPOPP_02400 6.3e-152
NNECPOPP_02401 2.3e-114 S GlcNAc-PI de-N-acetylase
NNECPOPP_02402 7.1e-122 C WbqC-like protein family
NNECPOPP_02403 7.6e-114 M Protein involved in cellulose biosynthesis
NNECPOPP_02404 6.7e-157 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NNECPOPP_02405 9.6e-148 5.1.3.2 M GDP-mannose 4,6 dehydratase
NNECPOPP_02406 1.4e-185 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NNECPOPP_02407 2.8e-217 1.1.1.136 M UDP binding domain
NNECPOPP_02408 8.2e-166 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NNECPOPP_02409 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NNECPOPP_02410 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NNECPOPP_02411 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNECPOPP_02412 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NNECPOPP_02413 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNECPOPP_02414 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NNECPOPP_02415 1.6e-252 araE EGP Major facilitator Superfamily
NNECPOPP_02416 5.5e-203 araR K transcriptional
NNECPOPP_02417 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNECPOPP_02418 5.1e-159 yvbU K Transcriptional regulator
NNECPOPP_02419 1e-154 yvbV EG EamA-like transporter family
NNECPOPP_02420 1.2e-239 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NNECPOPP_02421 1.1e-192 yvbX S Glycosyl hydrolase
NNECPOPP_02422 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NNECPOPP_02423 1e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NNECPOPP_02424 5.9e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NNECPOPP_02425 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNECPOPP_02426 5.6e-195 desK 2.7.13.3 T Histidine kinase
NNECPOPP_02427 1.4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
NNECPOPP_02428 6.4e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NNECPOPP_02429 2.2e-156 rsbQ S Alpha/beta hydrolase family
NNECPOPP_02430 3.5e-198 rsbU 3.1.3.3 T response regulator
NNECPOPP_02431 9.2e-250 galA 3.2.1.89 G arabinogalactan
NNECPOPP_02432 0.0 lacA 3.2.1.23 G beta-galactosidase
NNECPOPP_02433 7.2e-150 ganQ P transport
NNECPOPP_02434 5.5e-231 malC P COG1175 ABC-type sugar transport systems, permease components
NNECPOPP_02435 1.5e-231 cycB G COG2182 Maltose-binding periplasmic proteins domains
NNECPOPP_02436 1.8e-184 lacR K Transcriptional regulator
NNECPOPP_02437 2.7e-113 yvfI K COG2186 Transcriptional regulators
NNECPOPP_02438 2.2e-307 yvfH C L-lactate permease
NNECPOPP_02439 1.1e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NNECPOPP_02440 1e-31 yvfG S YvfG protein
NNECPOPP_02441 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
NNECPOPP_02442 3.3e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NNECPOPP_02443 3.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NNECPOPP_02444 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NNECPOPP_02445 5.9e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNECPOPP_02446 6.4e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NNECPOPP_02447 4.4e-205 epsI GM pyruvyl transferase
NNECPOPP_02448 5.8e-194 epsH GT2 S Glycosyltransferase like family 2
NNECPOPP_02449 1.1e-206 epsG S EpsG family
NNECPOPP_02450 5.4e-217 epsF GT4 M Glycosyl transferases group 1
NNECPOPP_02451 1.6e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NNECPOPP_02452 2.9e-223 epsD GT4 M Glycosyl transferase 4-like
NNECPOPP_02453 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NNECPOPP_02454 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NNECPOPP_02455 4e-122 ywqC M biosynthesis protein
NNECPOPP_02456 6.3e-76 slr K transcriptional
NNECPOPP_02457 9.4e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NNECPOPP_02459 5.1e-92 padC Q Phenolic acid decarboxylase
NNECPOPP_02460 5.8e-74 MA20_18690 S Protein of unknown function (DUF3237)
NNECPOPP_02461 2.2e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NNECPOPP_02462 3.3e-258 pbpE V Beta-lactamase
NNECPOPP_02463 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NNECPOPP_02464 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NNECPOPP_02465 1.8e-295 yveA E amino acid
NNECPOPP_02466 2.6e-106 yvdT K Transcriptional regulator
NNECPOPP_02467 4.3e-50 ykkC P Small Multidrug Resistance protein
NNECPOPP_02468 4.1e-50 sugE P Small Multidrug Resistance protein
NNECPOPP_02469 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NNECPOPP_02470 3.2e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
NNECPOPP_02471 2.8e-182 S Patatin-like phospholipase
NNECPOPP_02473 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NNECPOPP_02474 9.8e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NNECPOPP_02475 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NNECPOPP_02476 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NNECPOPP_02477 1e-154 malA S Protein of unknown function (DUF1189)
NNECPOPP_02478 9.5e-147 malD P transport
NNECPOPP_02479 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
NNECPOPP_02480 1.2e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NNECPOPP_02481 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NNECPOPP_02482 5.1e-173 yvdE K Transcriptional regulator
NNECPOPP_02483 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
NNECPOPP_02484 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
NNECPOPP_02485 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NNECPOPP_02486 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NNECPOPP_02487 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNECPOPP_02488 0.0 yxdM V ABC transporter (permease)
NNECPOPP_02489 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NNECPOPP_02490 3.4e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NNECPOPP_02491 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_02492 3.9e-33
NNECPOPP_02493 4.7e-145 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NNECPOPP_02494 1.6e-36 crh G Phosphocarrier protein Chr
NNECPOPP_02495 1.4e-170 whiA K May be required for sporulation
NNECPOPP_02496 2.1e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NNECPOPP_02497 5.7e-166 rapZ S Displays ATPase and GTPase activities
NNECPOPP_02498 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NNECPOPP_02499 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NNECPOPP_02500 1.1e-97 usp CBM50 M protein conserved in bacteria
NNECPOPP_02501 4.5e-277 S COG0457 FOG TPR repeat
NNECPOPP_02502 0.0 msbA2 3.6.3.44 V ABC transporter
NNECPOPP_02504 0.0
NNECPOPP_02505 1.6e-118
NNECPOPP_02506 3.4e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NNECPOPP_02507 6.8e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NNECPOPP_02508 4.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NNECPOPP_02509 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NNECPOPP_02510 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NNECPOPP_02511 1.9e-215 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NNECPOPP_02512 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NNECPOPP_02513 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NNECPOPP_02514 3.8e-139 yvpB NU protein conserved in bacteria
NNECPOPP_02515 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NNECPOPP_02516 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NNECPOPP_02517 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NNECPOPP_02518 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
NNECPOPP_02519 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NNECPOPP_02520 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NNECPOPP_02521 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NNECPOPP_02522 4.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNECPOPP_02523 3.6e-134 yvoA K transcriptional
NNECPOPP_02524 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NNECPOPP_02525 1.2e-50 yvlD S Membrane
NNECPOPP_02526 2.6e-26 pspB KT PspC domain
NNECPOPP_02527 2.4e-166 yvlB S Putative adhesin
NNECPOPP_02528 1.8e-48 yvlA
NNECPOPP_02529 5.7e-33 yvkN
NNECPOPP_02530 8.7e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NNECPOPP_02531 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NNECPOPP_02532 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NNECPOPP_02533 1.2e-30 csbA S protein conserved in bacteria
NNECPOPP_02534 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NNECPOPP_02535 2.7e-100 yvkB K Transcriptional regulator
NNECPOPP_02536 1.1e-226 yvkA EGP Major facilitator Superfamily
NNECPOPP_02537 1.2e-219 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNECPOPP_02538 5.3e-56 swrA S Swarming motility protein
NNECPOPP_02539 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NNECPOPP_02540 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NNECPOPP_02541 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NNECPOPP_02542 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
NNECPOPP_02543 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NNECPOPP_02544 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NNECPOPP_02545 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNECPOPP_02546 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NNECPOPP_02547 5.4e-65
NNECPOPP_02548 1.9e-08 fliT S bacterial-type flagellum organization
NNECPOPP_02549 6.5e-69 fliS N flagellar protein FliS
NNECPOPP_02550 1.4e-254 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NNECPOPP_02551 6.1e-57 flaG N flagellar protein FlaG
NNECPOPP_02552 7.1e-110 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NNECPOPP_02553 2.8e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NNECPOPP_02554 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NNECPOPP_02555 1.3e-49 yviE
NNECPOPP_02556 7.8e-155 flgL N Belongs to the bacterial flagellin family
NNECPOPP_02557 4.6e-264 flgK N flagellar hook-associated protein
NNECPOPP_02558 2.4e-78 flgN NOU FlgN protein
NNECPOPP_02559 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
NNECPOPP_02560 2e-73 yvyF S flagellar protein
NNECPOPP_02561 3.6e-126 comFC S Phosphoribosyl transferase domain
NNECPOPP_02562 3.7e-45 comFB S Late competence development protein ComFB
NNECPOPP_02563 4.4e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NNECPOPP_02564 6.2e-154 degV S protein conserved in bacteria
NNECPOPP_02565 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNECPOPP_02566 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NNECPOPP_02567 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NNECPOPP_02568 6e-163 yvhJ K Transcriptional regulator
NNECPOPP_02569 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NNECPOPP_02570 3.2e-236 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NNECPOPP_02571 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NNECPOPP_02572 1.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
NNECPOPP_02573 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
NNECPOPP_02574 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNECPOPP_02575 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NNECPOPP_02576 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNECPOPP_02577 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NNECPOPP_02578 1.5e-94 M Glycosyltransferase like family 2
NNECPOPP_02579 2.6e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NNECPOPP_02580 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NNECPOPP_02581 1e-11
NNECPOPP_02582 2.9e-157 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NNECPOPP_02583 9.1e-217 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNECPOPP_02584 1e-87 M Glycosyltransferase like family 2
NNECPOPP_02585 3.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NNECPOPP_02586 4.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NNECPOPP_02587 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NNECPOPP_02588 4e-271 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NNECPOPP_02589 1e-132 tagG GM Transport permease protein
NNECPOPP_02590 1.6e-211 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NNECPOPP_02591 1.2e-114 ggaA M Glycosyltransferase like family 2
NNECPOPP_02592 9.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NNECPOPP_02593 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NNECPOPP_02594 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NNECPOPP_02595 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NNECPOPP_02596 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NNECPOPP_02597 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NNECPOPP_02598 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NNECPOPP_02599 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NNECPOPP_02600 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNECPOPP_02601 2.1e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NNECPOPP_02602 3.5e-266 gerBA EG Spore germination protein
NNECPOPP_02603 5.4e-198 gerBB E Spore germination protein
NNECPOPP_02604 6e-213 gerAC S Spore germination protein
NNECPOPP_02605 7.8e-247 ywtG EGP Major facilitator Superfamily
NNECPOPP_02606 8.4e-171 ywtF K Transcriptional regulator
NNECPOPP_02607 9.1e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NNECPOPP_02608 4.9e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NNECPOPP_02609 3.6e-21 ywtC
NNECPOPP_02610 1.8e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NNECPOPP_02611 8.6e-70 pgsC S biosynthesis protein
NNECPOPP_02612 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NNECPOPP_02613 5.5e-178 rbsR K transcriptional
NNECPOPP_02614 1.6e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNECPOPP_02615 1.5e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NNECPOPP_02616 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NNECPOPP_02617 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NNECPOPP_02618 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NNECPOPP_02619 5.2e-90 batE T Sh3 type 3 domain protein
NNECPOPP_02620 8e-48 ywsA S Protein of unknown function (DUF3892)
NNECPOPP_02621 2.4e-95 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NNECPOPP_02622 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NNECPOPP_02623 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NNECPOPP_02624 1.1e-169 alsR K LysR substrate binding domain
NNECPOPP_02625 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NNECPOPP_02626 2e-123 ywrJ
NNECPOPP_02627 1.8e-129 cotB
NNECPOPP_02628 6e-210 cotH M Spore Coat
NNECPOPP_02629 3.7e-12
NNECPOPP_02630 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NNECPOPP_02631 5e-54 S Domain of unknown function (DUF4181)
NNECPOPP_02632 4.4e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NNECPOPP_02633 8e-82 ywrC K Transcriptional regulator
NNECPOPP_02634 1.2e-103 ywrB P Chromate transporter
NNECPOPP_02635 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
NNECPOPP_02637 1.1e-100 ywqN S NAD(P)H-dependent
NNECPOPP_02638 1e-159 K Transcriptional regulator
NNECPOPP_02639 1.8e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NNECPOPP_02640 3.9e-25
NNECPOPP_02641 3.5e-242 ywqJ S Pre-toxin TG
NNECPOPP_02642 3.9e-38 ywqI S Family of unknown function (DUF5344)
NNECPOPP_02643 9.7e-23 S Domain of unknown function (DUF5082)
NNECPOPP_02644 2.4e-152 ywqG S Domain of unknown function (DUF1963)
NNECPOPP_02645 3.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNECPOPP_02646 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NNECPOPP_02647 2.9e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NNECPOPP_02648 2.7e-116 ywqC M biosynthesis protein
NNECPOPP_02649 1.2e-17
NNECPOPP_02650 1.3e-306 ywqB S SWIM zinc finger
NNECPOPP_02651 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NNECPOPP_02652 9.7e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NNECPOPP_02653 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NNECPOPP_02654 9.8e-58 ssbB L Single-stranded DNA-binding protein
NNECPOPP_02655 1.9e-65 ywpG
NNECPOPP_02656 6.9e-66 ywpF S YwpF-like protein
NNECPOPP_02657 2.3e-84 srtA 3.4.22.70 M Sortase family
NNECPOPP_02658 0.0 M1-568 M cell wall anchor domain
NNECPOPP_02659 9e-174 M1-574 T Transcriptional regulatory protein, C terminal
NNECPOPP_02660 0.0 ywpD T PhoQ Sensor
NNECPOPP_02661 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NNECPOPP_02662 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNECPOPP_02663 2e-197 S aspartate phosphatase
NNECPOPP_02664 3.7e-140 flhP N flagellar basal body
NNECPOPP_02665 4.9e-124 flhO N flagellar basal body
NNECPOPP_02666 3.5e-180 mbl D Rod shape-determining protein
NNECPOPP_02667 3e-44 spoIIID K Stage III sporulation protein D
NNECPOPP_02668 8.8e-69 ywoH K COG1846 Transcriptional regulators
NNECPOPP_02669 4e-196 ywoG EGP Major facilitator Superfamily
NNECPOPP_02670 8.6e-217 ywoF P Right handed beta helix region
NNECPOPP_02671 7.5e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NNECPOPP_02672 6.3e-241 ywoD EGP Major facilitator superfamily
NNECPOPP_02673 1.5e-103 phzA Q Isochorismatase family
NNECPOPP_02674 2.2e-76
NNECPOPP_02675 7.4e-225 amt P Ammonium transporter
NNECPOPP_02676 1.6e-58 nrgB K Belongs to the P(II) protein family
NNECPOPP_02677 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NNECPOPP_02678 3.5e-73 ywnJ S VanZ like family
NNECPOPP_02679 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NNECPOPP_02680 1.8e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NNECPOPP_02681 5.7e-09 ywnC S Family of unknown function (DUF5362)
NNECPOPP_02682 2.2e-70 ywnF S Family of unknown function (DUF5392)
NNECPOPP_02683 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNECPOPP_02684 1.2e-143 mta K transcriptional
NNECPOPP_02685 2.6e-59 ywnC S Family of unknown function (DUF5362)
NNECPOPP_02686 1.6e-114 ywnB S NAD(P)H-binding
NNECPOPP_02687 1.7e-64 ywnA K Transcriptional regulator
NNECPOPP_02688 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NNECPOPP_02689 6.5e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NNECPOPP_02690 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NNECPOPP_02691 3.8e-11 csbD K CsbD-like
NNECPOPP_02692 3.8e-84 ywmF S Peptidase M50
NNECPOPP_02694 1.9e-102 S response regulator aspartate phosphatase
NNECPOPP_02695 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NNECPOPP_02696 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NNECPOPP_02698 1.2e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NNECPOPP_02699 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NNECPOPP_02700 4.4e-178 spoIID D Stage II sporulation protein D
NNECPOPP_02701 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNECPOPP_02702 3.7e-134 ywmB S TATA-box binding
NNECPOPP_02703 1.3e-32 ywzB S membrane
NNECPOPP_02704 4.8e-87 ywmA
NNECPOPP_02705 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NNECPOPP_02706 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NNECPOPP_02707 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NNECPOPP_02708 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NNECPOPP_02709 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNECPOPP_02710 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NNECPOPP_02711 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNECPOPP_02712 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NNECPOPP_02713 2.5e-62 atpI S ATP synthase
NNECPOPP_02714 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NNECPOPP_02715 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNECPOPP_02716 7.2e-95 ywlG S Belongs to the UPF0340 family
NNECPOPP_02717 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NNECPOPP_02718 8.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNECPOPP_02719 3.8e-91 mntP P Probably functions as a manganese efflux pump
NNECPOPP_02720 8.9e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NNECPOPP_02721 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NNECPOPP_02722 6.1e-112 spoIIR S stage II sporulation protein R
NNECPOPP_02723 4.8e-55 ywlA S Uncharacterised protein family (UPF0715)
NNECPOPP_02725 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NNECPOPP_02726 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NNECPOPP_02727 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNECPOPP_02728 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NNECPOPP_02729 8.6e-160 ywkB S Membrane transport protein
NNECPOPP_02730 0.0 sfcA 1.1.1.38 C malic enzyme
NNECPOPP_02731 1.6e-103 tdk 2.7.1.21 F thymidine kinase
NNECPOPP_02732 1.1e-32 rpmE J Binds the 23S rRNA
NNECPOPP_02733 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NNECPOPP_02734 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NNECPOPP_02735 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNECPOPP_02736 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NNECPOPP_02737 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NNECPOPP_02738 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NNECPOPP_02739 1.8e-90 ywjG S Domain of unknown function (DUF2529)
NNECPOPP_02740 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NNECPOPP_02741 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NNECPOPP_02742 2.8e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NNECPOPP_02743 0.0 fadF C COG0247 Fe-S oxidoreductase
NNECPOPP_02744 1.2e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NNECPOPP_02745 1.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NNECPOPP_02746 1.8e-41 ywjC
NNECPOPP_02747 5.3e-95 ywjB H RibD C-terminal domain
NNECPOPP_02748 0.0 ywjA V ABC transporter
NNECPOPP_02749 1.6e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNECPOPP_02750 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
NNECPOPP_02751 1.1e-93 narJ 1.7.5.1 C nitrate reductase
NNECPOPP_02752 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
NNECPOPP_02753 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNECPOPP_02754 7e-86 arfM T cyclic nucleotide binding
NNECPOPP_02755 4.3e-140 ywiC S YwiC-like protein
NNECPOPP_02756 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NNECPOPP_02757 3.9e-213 narK P COG2223 Nitrate nitrite transporter
NNECPOPP_02758 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NNECPOPP_02759 4.7e-73 ywiB S protein conserved in bacteria
NNECPOPP_02760 1e-07 S Bacteriocin subtilosin A
NNECPOPP_02761 1.4e-269 C Fe-S oxidoreductases
NNECPOPP_02763 5.7e-132 cbiO V ABC transporter
NNECPOPP_02764 8.5e-235 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NNECPOPP_02765 2e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
NNECPOPP_02766 2.9e-248 L Peptidase, M16
NNECPOPP_02768 1.8e-243 ywhL CO amine dehydrogenase activity
NNECPOPP_02769 8.6e-190 ywhK CO amine dehydrogenase activity
NNECPOPP_02770 3.1e-79 S aspartate phosphatase
NNECPOPP_02772 8.1e-10
NNECPOPP_02773 1.3e-20
NNECPOPP_02776 4.4e-59 V ATPases associated with a variety of cellular activities
NNECPOPP_02778 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NNECPOPP_02779 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NNECPOPP_02780 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NNECPOPP_02781 2e-94 ywhD S YwhD family
NNECPOPP_02782 5.1e-119 ywhC S Peptidase family M50
NNECPOPP_02783 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NNECPOPP_02784 3.3e-71 ywhA K Transcriptional regulator
NNECPOPP_02785 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNECPOPP_02787 2.2e-236 mmr U Major Facilitator Superfamily
NNECPOPP_02788 6.9e-78 yffB K Transcriptional regulator
NNECPOPP_02789 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NNECPOPP_02790 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
NNECPOPP_02791 3.1e-36 ywzC S Belongs to the UPF0741 family
NNECPOPP_02792 6e-111 rsfA_1
NNECPOPP_02793 2.4e-156 ywfM EG EamA-like transporter family
NNECPOPP_02794 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NNECPOPP_02795 1.1e-156 cysL K Transcriptional regulator
NNECPOPP_02796 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NNECPOPP_02797 3.3e-146 ywfI C May function as heme-dependent peroxidase
NNECPOPP_02798 2.9e-137 IQ Enoyl-(Acyl carrier protein) reductase
NNECPOPP_02799 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
NNECPOPP_02800 7.3e-209 bacE EGP Major facilitator Superfamily
NNECPOPP_02801 1.4e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NNECPOPP_02802 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_02803 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NNECPOPP_02804 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NNECPOPP_02805 4.6e-206 ywfA EGP Major facilitator Superfamily
NNECPOPP_02806 2.8e-249 lysP E amino acid
NNECPOPP_02807 0.0 rocB E arginine degradation protein
NNECPOPP_02808 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NNECPOPP_02809 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NNECPOPP_02810 1.2e-77
NNECPOPP_02811 1.3e-86 spsL 5.1.3.13 M Spore Coat
NNECPOPP_02812 7.6e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNECPOPP_02813 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NNECPOPP_02814 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NNECPOPP_02815 1.4e-184 spsG M Spore Coat
NNECPOPP_02816 3.8e-128 spsF M Spore Coat
NNECPOPP_02817 6.6e-212 spsE 2.5.1.56 M acid synthase
NNECPOPP_02818 1.2e-163 spsD 2.3.1.210 K Spore Coat
NNECPOPP_02819 6.7e-223 spsC E Belongs to the DegT DnrJ EryC1 family
NNECPOPP_02820 3.1e-275 spsB M Capsule polysaccharide biosynthesis protein
NNECPOPP_02821 1.8e-144 spsA M Spore Coat
NNECPOPP_02822 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NNECPOPP_02823 4.3e-59 ywdK S small membrane protein
NNECPOPP_02824 1.3e-238 ywdJ F Xanthine uracil
NNECPOPP_02825 5e-48 ywdI S Family of unknown function (DUF5327)
NNECPOPP_02826 3.4e-258 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NNECPOPP_02827 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NNECPOPP_02828 4.7e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
NNECPOPP_02830 5.8e-112 ywdD
NNECPOPP_02831 1.3e-57 pex K Transcriptional regulator PadR-like family
NNECPOPP_02832 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NNECPOPP_02833 7e-29 ywdA
NNECPOPP_02834 9.5e-288 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NNECPOPP_02835 2.8e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NNECPOPP_02836 2.6e-138 focA P Formate/nitrite transporter
NNECPOPP_02837 1.2e-149 sacT K transcriptional antiterminator
NNECPOPP_02839 0.0 vpr O Belongs to the peptidase S8 family
NNECPOPP_02840 7.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNECPOPP_02841 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NNECPOPP_02842 2.9e-202 rodA D Belongs to the SEDS family
NNECPOPP_02843 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NNECPOPP_02844 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NNECPOPP_02845 2.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NNECPOPP_02846 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NNECPOPP_02847 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NNECPOPP_02848 1e-35 ywzA S membrane
NNECPOPP_02849 7.5e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NNECPOPP_02850 1.4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNECPOPP_02851 1.4e-58 gtcA S GtrA-like protein
NNECPOPP_02852 1.1e-121 ywcC K transcriptional regulator
NNECPOPP_02854 6.4e-48 ywcB S Protein of unknown function, DUF485
NNECPOPP_02855 3.1e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNECPOPP_02856 4.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NNECPOPP_02857 3.2e-223 ywbN P Dyp-type peroxidase family protein
NNECPOPP_02858 4.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
NNECPOPP_02859 2.7e-250 P COG0672 High-affinity Fe2 Pb2 permease
NNECPOPP_02860 1.6e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NNECPOPP_02861 6.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NNECPOPP_02862 4.3e-153 ywbI K Transcriptional regulator
NNECPOPP_02863 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NNECPOPP_02864 5.2e-111 ywbG M effector of murein hydrolase
NNECPOPP_02865 2.6e-206 ywbF EGP Major facilitator Superfamily
NNECPOPP_02866 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NNECPOPP_02867 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
NNECPOPP_02868 9.9e-67 ywbC 4.4.1.5 E glyoxalase
NNECPOPP_02869 2e-126 ywbB S Protein of unknown function (DUF2711)
NNECPOPP_02870 5.4e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNECPOPP_02871 2.1e-274 epr 3.4.21.62 O Belongs to the peptidase S8 family
NNECPOPP_02872 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NNECPOPP_02873 1.6e-149 sacY K transcriptional antiterminator
NNECPOPP_02874 1.7e-167 gspA M General stress
NNECPOPP_02875 1.3e-123 ywaF S Integral membrane protein
NNECPOPP_02876 2.3e-87 ywaE K Transcriptional regulator
NNECPOPP_02877 3.2e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNECPOPP_02878 2.3e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NNECPOPP_02879 5.3e-92 K Helix-turn-helix XRE-family like proteins
NNECPOPP_02880 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
NNECPOPP_02881 4e-130 ynfM EGP Major facilitator Superfamily
NNECPOPP_02882 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NNECPOPP_02883 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NNECPOPP_02884 5e-14 S D-Ala-teichoic acid biosynthesis protein
NNECPOPP_02885 4.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_02886 1.6e-232 dltB M membrane protein involved in D-alanine export
NNECPOPP_02887 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_02888 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NNECPOPP_02889 2.8e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_02890 1.2e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NNECPOPP_02891 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NNECPOPP_02892 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NNECPOPP_02893 1.1e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNECPOPP_02894 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NNECPOPP_02895 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NNECPOPP_02896 1.1e-19 yxzF
NNECPOPP_02897 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NNECPOPP_02898 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NNECPOPP_02899 7.1e-212 yxlH EGP Major facilitator Superfamily
NNECPOPP_02900 4.4e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NNECPOPP_02901 3.1e-164 yxlF V ABC transporter, ATP-binding protein
NNECPOPP_02902 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NNECPOPP_02903 1.2e-31
NNECPOPP_02904 3.9e-48 yxlC S Family of unknown function (DUF5345)
NNECPOPP_02905 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_02906 6.6e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NNECPOPP_02907 1.4e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNECPOPP_02908 0.0 cydD V ATP-binding protein
NNECPOPP_02909 0.0 cydD V ATP-binding
NNECPOPP_02910 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NNECPOPP_02911 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
NNECPOPP_02912 1.5e-229 cimH C COG3493 Na citrate symporter
NNECPOPP_02913 1.2e-310 3.4.24.84 O Peptidase family M48
NNECPOPP_02915 3.6e-154 yxkH G Polysaccharide deacetylase
NNECPOPP_02916 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NNECPOPP_02917 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
NNECPOPP_02918 5.7e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNECPOPP_02919 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNECPOPP_02920 2.2e-136
NNECPOPP_02921 5.7e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NNECPOPP_02922 3.3e-94 yxkA S Phosphatidylethanolamine-binding protein
NNECPOPP_02923 2.1e-165 yxjO K LysR substrate binding domain
NNECPOPP_02924 1e-76 S Protein of unknown function (DUF1453)
NNECPOPP_02925 4.1e-191 yxjM T Signal transduction histidine kinase
NNECPOPP_02926 7.8e-112 K helix_turn_helix, Lux Regulon
NNECPOPP_02927 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NNECPOPP_02930 1.6e-85 yxjI S LURP-one-related
NNECPOPP_02931 8.7e-220 yxjG 2.1.1.14 E Methionine synthase
NNECPOPP_02932 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
NNECPOPP_02933 4.1e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NNECPOPP_02934 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NNECPOPP_02935 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NNECPOPP_02936 9.1e-251 yxjC EG COG2610 H gluconate symporter and related permeases
NNECPOPP_02937 1.4e-141 rlmA 2.1.1.187 Q Methyltransferase domain
NNECPOPP_02938 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNECPOPP_02939 3.2e-105 T Domain of unknown function (DUF4163)
NNECPOPP_02940 5.6e-46 yxiS
NNECPOPP_02941 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NNECPOPP_02942 6.6e-224 citH C Citrate transporter
NNECPOPP_02943 7.3e-143 exoK GH16 M licheninase activity
NNECPOPP_02944 8.3e-151 licT K transcriptional antiterminator
NNECPOPP_02945 6.2e-112
NNECPOPP_02946 3.4e-228 yxiO S COG2270 Permeases of the major facilitator superfamily
NNECPOPP_02947 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NNECPOPP_02948 3.7e-210 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NNECPOPP_02951 1.2e-43 yxiJ S YxiJ-like protein
NNECPOPP_02952 1.6e-85 yxiI S Protein of unknown function (DUF2716)
NNECPOPP_02953 7.4e-164 yxxF EG EamA-like transporter family
NNECPOPP_02954 3.7e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_02955 9.3e-122 1.14.11.45 E 2OG-Fe dioxygenase
NNECPOPP_02956 1.1e-72 yxiE T Belongs to the universal stress protein A family
NNECPOPP_02957 2.1e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NNECPOPP_02958 2.5e-311 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NNECPOPP_02959 1.4e-50
NNECPOPP_02960 2.9e-78 S SMI1 / KNR4 family
NNECPOPP_02961 0.0 S nuclease activity
NNECPOPP_02962 5.2e-38 yxiC S Family of unknown function (DUF5344)
NNECPOPP_02963 5.1e-20 S Domain of unknown function (DUF5082)
NNECPOPP_02964 9e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NNECPOPP_02965 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NNECPOPP_02966 9.8e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
NNECPOPP_02967 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NNECPOPP_02968 6.7e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NNECPOPP_02969 1.8e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NNECPOPP_02970 2.2e-249 lysP E amino acid
NNECPOPP_02971 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NNECPOPP_02972 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNECPOPP_02973 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NNECPOPP_02974 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NNECPOPP_02975 2e-152 yxxB S Domain of Unknown Function (DUF1206)
NNECPOPP_02976 4.4e-200 eutH E Ethanolamine utilisation protein, EutH
NNECPOPP_02977 1.2e-249 yxeQ S MmgE/PrpD family
NNECPOPP_02978 1.4e-212 yxeP 3.5.1.47 E hydrolase activity
NNECPOPP_02979 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NNECPOPP_02980 7.2e-113 yxeN P COG0765 ABC-type amino acid transport system, permease component
NNECPOPP_02981 7.2e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NNECPOPP_02982 6.1e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNECPOPP_02983 4.9e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNECPOPP_02984 5.7e-183 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NNECPOPP_02985 5.2e-150 yidA S hydrolases of the HAD superfamily
NNECPOPP_02988 1.3e-20 yxeE
NNECPOPP_02989 5.6e-16 yxeD
NNECPOPP_02990 1.4e-68
NNECPOPP_02991 3.3e-175 fhuD P ABC transporter
NNECPOPP_02992 1.3e-57 yxeA S Protein of unknown function (DUF1093)
NNECPOPP_02993 0.0 yxdM V ABC transporter (permease)
NNECPOPP_02994 9.4e-141 yxdL V ABC transporter, ATP-binding protein
NNECPOPP_02995 4.5e-180 T PhoQ Sensor
NNECPOPP_02996 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_02997 6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NNECPOPP_02998 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NNECPOPP_02999 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NNECPOPP_03000 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NNECPOPP_03001 2.1e-233 iolF EGP Major facilitator Superfamily
NNECPOPP_03002 1.4e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NNECPOPP_03003 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NNECPOPP_03004 5.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NNECPOPP_03005 7.8e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NNECPOPP_03006 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNECPOPP_03007 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NNECPOPP_03008 4.1e-175 iolS C Aldo keto reductase
NNECPOPP_03010 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NNECPOPP_03011 2.3e-246 csbC EGP Major facilitator Superfamily
NNECPOPP_03012 0.0 htpG O Molecular chaperone. Has ATPase activity
NNECPOPP_03014 1.5e-149 IQ Enoyl-(Acyl carrier protein) reductase
NNECPOPP_03015 1.9e-206 yxbF K Bacterial regulatory proteins, tetR family
NNECPOPP_03016 4.2e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NNECPOPP_03017 4.6e-20 yxaI S membrane protein domain
NNECPOPP_03018 1.2e-92 S PQQ-like domain
NNECPOPP_03019 3.5e-65 S Family of unknown function (DUF5391)
NNECPOPP_03020 6.9e-75 yxaI S membrane protein domain
NNECPOPP_03021 6.7e-226 P Protein of unknown function (DUF418)
NNECPOPP_03022 1.9e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
NNECPOPP_03023 2.7e-100 yxaF K Transcriptional regulator
NNECPOPP_03024 9.5e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NNECPOPP_03025 9.8e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NNECPOPP_03026 5.2e-50 S LrgA family
NNECPOPP_03027 1.3e-117 yxaC M effector of murein hydrolase
NNECPOPP_03028 1.7e-190 yxaB GM Polysaccharide pyruvyl transferase
NNECPOPP_03029 1.6e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NNECPOPP_03030 7.3e-127 gntR K transcriptional
NNECPOPP_03031 1e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NNECPOPP_03032 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
NNECPOPP_03033 5.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNECPOPP_03034 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NNECPOPP_03035 3.3e-286 ahpF O Alkyl hydroperoxide reductase
NNECPOPP_03036 3.5e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NNECPOPP_03037 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
NNECPOPP_03038 1.5e-124 yydK K Transcriptional regulator
NNECPOPP_03039 1.6e-118 S ABC-2 family transporter protein
NNECPOPP_03040 1e-108 prrC P ABC transporter
NNECPOPP_03041 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NNECPOPP_03042 0.0 O growth
NNECPOPP_03043 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NNECPOPP_03044 1.1e-09 S YyzF-like protein
NNECPOPP_03045 7.2e-71
NNECPOPP_03046 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NNECPOPP_03048 5.7e-31 yycQ S Protein of unknown function (DUF2651)
NNECPOPP_03049 4.2e-209 yycP
NNECPOPP_03050 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NNECPOPP_03051 2.2e-84 yycN 2.3.1.128 K Acetyltransferase
NNECPOPP_03052 4.7e-186 S aspartate phosphatase
NNECPOPP_03054 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NNECPOPP_03055 1.3e-260 rocE E amino acid
NNECPOPP_03056 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NNECPOPP_03057 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NNECPOPP_03058 1.8e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NNECPOPP_03059 1.5e-94 K PFAM response regulator receiver
NNECPOPP_03060 2.6e-73 S Peptidase propeptide and YPEB domain
NNECPOPP_03061 1.9e-33 S Peptidase propeptide and YPEB domain
NNECPOPP_03062 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNECPOPP_03063 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NNECPOPP_03064 1.8e-153 yycI S protein conserved in bacteria
NNECPOPP_03065 2.9e-257 yycH S protein conserved in bacteria
NNECPOPP_03066 0.0 vicK 2.7.13.3 T Histidine kinase
NNECPOPP_03067 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_03069 6.7e-167 ygxA S Nucleotidyltransferase-like
NNECPOPP_03070 2.8e-55 ygzB S UPF0295 protein
NNECPOPP_03071 4e-80 perR P Belongs to the Fur family
NNECPOPP_03072 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NNECPOPP_03073 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NNECPOPP_03074 8.7e-180 ygaE S Membrane
NNECPOPP_03075 1.8e-301 ygaD V ABC transporter
NNECPOPP_03076 1.3e-104 ygaC J Belongs to the UPF0374 family
NNECPOPP_03077 1.5e-37 ygaB S YgaB-like protein
NNECPOPP_03078 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NNECPOPP_03079 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_03080 6.9e-36 yfhS
NNECPOPP_03081 9.5e-210 mutY L A G-specific
NNECPOPP_03082 5.5e-186 yfhP S membrane-bound metal-dependent
NNECPOPP_03083 0.0 yfhO S Bacterial membrane protein YfhO
NNECPOPP_03084 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NNECPOPP_03085 4.8e-170 yfhM S Alpha beta hydrolase
NNECPOPP_03086 1e-47 yfhL S SdpI/YhfL protein family
NNECPOPP_03087 6.6e-90 batE T Bacterial SH3 domain homologues
NNECPOPP_03088 1.3e-44 yfhJ S WVELL protein
NNECPOPP_03089 6.2e-20 sspK S reproduction
NNECPOPP_03090 1.5e-209 yfhI EGP Major facilitator Superfamily
NNECPOPP_03092 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NNECPOPP_03093 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NNECPOPP_03094 5.5e-172 yfhF S nucleoside-diphosphate sugar epimerase
NNECPOPP_03096 2.1e-25 yfhD S YfhD-like protein
NNECPOPP_03097 1.5e-106 yfhC C nitroreductase
NNECPOPP_03098 4.3e-166 yfhB 5.3.3.17 S PhzF family
NNECPOPP_03099 2.2e-169 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_03100 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_03101 1.9e-175 yfiY P ABC transporter substrate-binding protein
NNECPOPP_03102 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNECPOPP_03103 5.8e-80 yfiV K transcriptional
NNECPOPP_03104 9.6e-286 yfiU EGP Major facilitator Superfamily
NNECPOPP_03105 1.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
NNECPOPP_03106 1.5e-209 yfiS EGP Major facilitator Superfamily
NNECPOPP_03107 7.1e-107 yfiR K Transcriptional regulator
NNECPOPP_03108 2.6e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NNECPOPP_03109 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NNECPOPP_03110 8.3e-99 padR K transcriptional
NNECPOPP_03111 5.4e-201 V COG0842 ABC-type multidrug transport system, permease component
NNECPOPP_03112 5.8e-206 V ABC-2 family transporter protein
NNECPOPP_03113 8.9e-170 V ABC transporter, ATP-binding protein
NNECPOPP_03114 7.9e-112 KT LuxR family transcriptional regulator
NNECPOPP_03115 3.6e-213 yxjM T Histidine kinase
NNECPOPP_03117 2.5e-233 S Oxidoreductase
NNECPOPP_03118 8.4e-184 G Xylose isomerase
NNECPOPP_03119 1.8e-262 iolT EGP Major facilitator Superfamily
NNECPOPP_03120 1.5e-177 K AraC-like ligand binding domain
NNECPOPP_03121 2.8e-162 yfiE 1.13.11.2 S glyoxalase
NNECPOPP_03122 6.4e-64 mhqP S DoxX
NNECPOPP_03123 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NNECPOPP_03124 9.3e-306 yfiB3 V ABC transporter
NNECPOPP_03125 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NNECPOPP_03126 6e-140 glvR K Helix-turn-helix domain, rpiR family
NNECPOPP_03127 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NNECPOPP_03128 2.6e-44 yfjA S Belongs to the WXG100 family
NNECPOPP_03129 9.6e-172 yfjB
NNECPOPP_03130 2.4e-123 yfjC
NNECPOPP_03131 1.8e-85 S Family of unknown function (DUF5381)
NNECPOPP_03132 4e-56 yfjF S UPF0060 membrane protein
NNECPOPP_03133 9.8e-25 sspH S Belongs to the SspH family
NNECPOPP_03134 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NNECPOPP_03135 1.9e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNECPOPP_03136 1.6e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNECPOPP_03137 4.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNECPOPP_03138 3.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNECPOPP_03139 1.1e-83 yfjM S Psort location Cytoplasmic, score
NNECPOPP_03140 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNECPOPP_03141 2.6e-43 S YfzA-like protein
NNECPOPP_03142 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNECPOPP_03143 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NNECPOPP_03144 1.7e-184 corA P Mediates influx of magnesium ions
NNECPOPP_03145 9.5e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NNECPOPP_03146 2.6e-154 pdaA G deacetylase
NNECPOPP_03147 1.1e-26 yfjT
NNECPOPP_03148 5.4e-222 yfkA S YfkB-like domain
NNECPOPP_03149 6e-149 yfkC M Mechanosensitive ion channel
NNECPOPP_03150 1.2e-146 yfkD S YfkD-like protein
NNECPOPP_03151 6.1e-183 cax P COG0387 Ca2 H antiporter
NNECPOPP_03152 4.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NNECPOPP_03153 5e-08
NNECPOPP_03154 1.3e-143 yihY S Belongs to the UPF0761 family
NNECPOPP_03155 2.4e-50 yfkI S gas vesicle protein
NNECPOPP_03156 1.9e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNECPOPP_03157 2.3e-28 yfkK S Belongs to the UPF0435 family
NNECPOPP_03158 1.2e-206 ydiM EGP Major facilitator Superfamily
NNECPOPP_03159 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
NNECPOPP_03160 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NNECPOPP_03161 1.1e-124 yfkO C nitroreductase
NNECPOPP_03162 1.8e-133 treR K transcriptional
NNECPOPP_03163 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NNECPOPP_03164 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NNECPOPP_03165 4.9e-282 yfkQ EG Spore germination protein
NNECPOPP_03166 2.1e-205 yfkR S spore germination
NNECPOPP_03168 1.3e-193 E Spore germination protein
NNECPOPP_03169 2.2e-252 agcS_1 E Sodium alanine symporter
NNECPOPP_03170 6e-67 yhdN S Domain of unknown function (DUF1992)
NNECPOPP_03171 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NNECPOPP_03172 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NNECPOPP_03173 4.2e-138 map 3.4.11.18 E Methionine aminopeptidase
NNECPOPP_03174 5.3e-50 yflH S Protein of unknown function (DUF3243)
NNECPOPP_03175 1.6e-18 yflI
NNECPOPP_03176 4e-18 yflJ S Protein of unknown function (DUF2639)
NNECPOPP_03177 8.4e-122 yflK S protein conserved in bacteria
NNECPOPP_03178 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NNECPOPP_03179 5.6e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NNECPOPP_03180 1.8e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NNECPOPP_03181 8.5e-227 citM C Citrate transporter
NNECPOPP_03182 3.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
NNECPOPP_03183 2.6e-118 citT T response regulator
NNECPOPP_03184 1.8e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NNECPOPP_03185 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
NNECPOPP_03186 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NNECPOPP_03187 7.6e-58 yflT S Heat induced stress protein YflT
NNECPOPP_03188 5e-24 S Protein of unknown function (DUF3212)
NNECPOPP_03189 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NNECPOPP_03190 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_03191 6.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_03192 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NNECPOPP_03193 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
NNECPOPP_03194 2.2e-213 G Major Facilitator Superfamily
NNECPOPP_03195 8.8e-187 yfmJ S N-terminal domain of oxidoreductase
NNECPOPP_03196 2.3e-75 yfmK 2.3.1.128 K acetyltransferase
NNECPOPP_03197 5.9e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NNECPOPP_03198 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNECPOPP_03199 9.5e-209 yfmO EGP Major facilitator Superfamily
NNECPOPP_03200 9e-69 yfmP K transcriptional
NNECPOPP_03201 1.1e-72 yfmQ S Uncharacterised protein from bacillus cereus group
NNECPOPP_03202 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNECPOPP_03203 1.1e-113 yfmS NT chemotaxis protein
NNECPOPP_03204 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNECPOPP_03205 6.4e-241 yfnA E amino acid
NNECPOPP_03206 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NNECPOPP_03207 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
NNECPOPP_03208 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
NNECPOPP_03209 1.4e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NNECPOPP_03210 5.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
NNECPOPP_03211 4.1e-186 yfnG 4.2.1.45 M dehydratase
NNECPOPP_03212 8.7e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
NNECPOPP_03213 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NNECPOPP_03214 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NNECPOPP_03215 3.6e-199 yetN S Protein of unknown function (DUF3900)
NNECPOPP_03216 9.8e-208 yetM CH FAD binding domain
NNECPOPP_03217 1.9e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
NNECPOPP_03218 5.3e-105 yetJ S Belongs to the BI1 family
NNECPOPP_03219 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NNECPOPP_03220 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNECPOPP_03221 2.4e-34
NNECPOPP_03222 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNECPOPP_03223 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NNECPOPP_03224 4e-122 yetF S membrane
NNECPOPP_03225 8.4e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NNECPOPP_03226 5e-162 lplC G Binding-protein-dependent transport system inner membrane component
NNECPOPP_03227 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NNECPOPP_03228 4e-289 lplA G Bacterial extracellular solute-binding protein
NNECPOPP_03229 0.0 yetA
NNECPOPP_03230 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NNECPOPP_03231 2e-123 yesY E GDSL-like Lipase/Acylhydrolase
NNECPOPP_03232 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NNECPOPP_03233 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NNECPOPP_03234 1.1e-112 yesV S Protein of unknown function, DUF624
NNECPOPP_03235 1.9e-126 yesU S Domain of unknown function (DUF1961)
NNECPOPP_03236 6.7e-130 E GDSL-like Lipase/Acylhydrolase
NNECPOPP_03237 0.0 yesS K Transcriptional regulator
NNECPOPP_03238 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NNECPOPP_03239 2.9e-162 yesQ P Binding-protein-dependent transport system inner membrane component
NNECPOPP_03240 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NNECPOPP_03241 3.3e-247 yesO G Bacterial extracellular solute-binding protein
NNECPOPP_03242 6.8e-201 yesN K helix_turn_helix, arabinose operon control protein
NNECPOPP_03243 0.0 yesM 2.7.13.3 T Histidine kinase
NNECPOPP_03244 3.5e-101 yesL S Protein of unknown function, DUF624
NNECPOPP_03246 6e-102 yesJ K Acetyltransferase (GNAT) family
NNECPOPP_03247 5.2e-104 cotJC P Spore Coat
NNECPOPP_03248 1.5e-45 cotJB S CotJB protein
NNECPOPP_03249 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NNECPOPP_03250 1.1e-150 yesF GM NAD(P)H-binding
NNECPOPP_03251 5.3e-80 yesE S SnoaL-like domain
NNECPOPP_03252 8e-100 dhaR3 K Transcriptional regulator
NNECPOPP_03254 2.7e-126 yeeN K transcriptional regulatory protein
NNECPOPP_03256 1.8e-212 S Tetratricopeptide repeat
NNECPOPP_03257 5.5e-52
NNECPOPP_03258 1.1e-100 L endonuclease activity
NNECPOPP_03260 1.5e-187 yobL S Bacterial EndoU nuclease
NNECPOPP_03261 1.3e-42 S Immunity protein 22
NNECPOPP_03263 3.4e-59 S Tetratricopeptide repeat
NNECPOPP_03265 9.9e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNECPOPP_03266 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NNECPOPP_03267 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NNECPOPP_03268 7.4e-147 yerO K Transcriptional regulator
NNECPOPP_03269 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNECPOPP_03270 5.6e-08 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NNECPOPP_03271 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNECPOPP_03272 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNECPOPP_03273 1.6e-123 sapB S MgtC SapB transporter
NNECPOPP_03274 7.8e-196 yerI S homoserine kinase type II (protein kinase fold)
NNECPOPP_03275 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NNECPOPP_03276 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NNECPOPP_03277 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NNECPOPP_03278 3.2e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NNECPOPP_03280 1.3e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NNECPOPP_03281 4.8e-51 yerC S protein conserved in bacteria
NNECPOPP_03282 3.7e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NNECPOPP_03283 0.0 yerA 3.5.4.2 F adenine deaminase
NNECPOPP_03284 2.7e-27 S Protein of unknown function (DUF2892)
NNECPOPP_03285 1.2e-225 yjeH E Amino acid permease
NNECPOPP_03286 4.3e-71 K helix_turn_helix ASNC type
NNECPOPP_03287 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
NNECPOPP_03288 3.9e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NNECPOPP_03289 7e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NNECPOPP_03290 8.4e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NNECPOPP_03291 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NNECPOPP_03292 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNECPOPP_03293 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNECPOPP_03294 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNECPOPP_03295 1.7e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NNECPOPP_03296 1.3e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NNECPOPP_03297 3.8e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NNECPOPP_03298 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NNECPOPP_03299 8e-28 yebG S NETI protein
NNECPOPP_03300 8.9e-93 yebE S UPF0316 protein
NNECPOPP_03302 2.3e-118 yebC M Membrane
NNECPOPP_03303 1e-211 pbuG S permease
NNECPOPP_03304 1.5e-243 S Domain of unknown function (DUF4179)
NNECPOPP_03305 2.1e-62 K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_03306 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NNECPOPP_03307 0.0 yebA E COG1305 Transglutaminase-like enzymes
NNECPOPP_03308 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NNECPOPP_03309 3e-176 yeaC S COG0714 MoxR-like ATPases
NNECPOPP_03310 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNECPOPP_03311 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NNECPOPP_03312 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NNECPOPP_03313 2.5e-178 yeaA S Protein of unknown function (DUF4003)
NNECPOPP_03314 1.7e-156 ydjP I Alpha/beta hydrolase family
NNECPOPP_03315 1.4e-34 ydjO S Cold-inducible protein YdjO
NNECPOPP_03317 3.8e-153 ydjN U Involved in the tonB-independent uptake of proteins
NNECPOPP_03318 4.5e-64 ydjM M Lytic transglycolase
NNECPOPP_03319 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NNECPOPP_03320 1.7e-257 iolT EGP Major facilitator Superfamily
NNECPOPP_03321 5.7e-194 S Ion transport 2 domain protein
NNECPOPP_03322 2e-148 ydjI S virion core protein (lumpy skin disease virus)
NNECPOPP_03323 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NNECPOPP_03324 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNECPOPP_03325 8.7e-114 pspA KT Phage shock protein A
NNECPOPP_03326 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NNECPOPP_03327 1.1e-253 gutA G MFS/sugar transport protein
NNECPOPP_03328 2.5e-200 gutB 1.1.1.14 E Dehydrogenase
NNECPOPP_03329 0.0 K NB-ARC domain
NNECPOPP_03330 1.1e-149 ydjC S Abhydrolase domain containing 18
NNECPOPP_03331 6.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NNECPOPP_03332 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NNECPOPP_03333 7.9e-129 ydiL S CAAX protease self-immunity
NNECPOPP_03334 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NNECPOPP_03335 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NNECPOPP_03336 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NNECPOPP_03337 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NNECPOPP_03338 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NNECPOPP_03339 0.0 ydiF S ABC transporter
NNECPOPP_03340 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NNECPOPP_03341 8.1e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NNECPOPP_03342 3.4e-126 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NNECPOPP_03343 2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NNECPOPP_03344 6.5e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NNECPOPP_03346 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NNECPOPP_03347 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NNECPOPP_03348 1.2e-84 gerD
NNECPOPP_03349 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NNECPOPP_03350 4.3e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NNECPOPP_03351 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NNECPOPP_03352 6.9e-144 ybaJ Q Methyltransferase domain
NNECPOPP_03353 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NNECPOPP_03354 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NNECPOPP_03355 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NNECPOPP_03356 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNECPOPP_03357 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNECPOPP_03358 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNECPOPP_03359 3.6e-58 rplQ J Ribosomal protein L17
NNECPOPP_03360 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNECPOPP_03361 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NNECPOPP_03362 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NNECPOPP_03363 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NNECPOPP_03364 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NNECPOPP_03365 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NNECPOPP_03366 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NNECPOPP_03367 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NNECPOPP_03368 1.8e-72 rplO J binds to the 23S rRNA
NNECPOPP_03369 1.9e-23 rpmD J Ribosomal protein L30
NNECPOPP_03370 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NNECPOPP_03371 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NNECPOPP_03372 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NNECPOPP_03373 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NNECPOPP_03374 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNECPOPP_03375 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NNECPOPP_03376 1.1e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NNECPOPP_03377 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NNECPOPP_03378 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NNECPOPP_03379 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NNECPOPP_03380 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NNECPOPP_03381 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NNECPOPP_03382 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NNECPOPP_03383 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NNECPOPP_03384 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NNECPOPP_03385 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NNECPOPP_03386 3e-105 rplD J Forms part of the polypeptide exit tunnel
NNECPOPP_03387 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NNECPOPP_03388 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NNECPOPP_03389 2.6e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NNECPOPP_03390 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NNECPOPP_03391 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NNECPOPP_03392 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NNECPOPP_03393 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NNECPOPP_03394 8.8e-32 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NNECPOPP_03395 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNECPOPP_03396 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNECPOPP_03397 4.1e-107 rsmC 2.1.1.172 J Methyltransferase
NNECPOPP_03398 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NNECPOPP_03399 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NNECPOPP_03400 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NNECPOPP_03401 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NNECPOPP_03402 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
NNECPOPP_03403 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NNECPOPP_03404 4.4e-115 sigH K Belongs to the sigma-70 factor family
NNECPOPP_03405 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NNECPOPP_03406 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNECPOPP_03407 1.2e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NNECPOPP_03408 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NNECPOPP_03409 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NNECPOPP_03410 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NNECPOPP_03411 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NNECPOPP_03412 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NNECPOPP_03413 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NNECPOPP_03414 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NNECPOPP_03415 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NNECPOPP_03416 0.0 clpC O Belongs to the ClpA ClpB family
NNECPOPP_03417 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NNECPOPP_03418 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NNECPOPP_03419 2.9e-76 ctsR K Belongs to the CtsR family
NNECPOPP_03420 3.4e-39 S COG NOG14552 non supervised orthologous group
NNECPOPP_03423 6.1e-157 ydhU P Catalase
NNECPOPP_03424 1.2e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NNECPOPP_03425 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NNECPOPP_03426 5.6e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NNECPOPP_03427 1.1e-132 ydhQ K UTRA
NNECPOPP_03428 6.4e-281 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NNECPOPP_03429 1.7e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNECPOPP_03430 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NNECPOPP_03431 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NNECPOPP_03432 1e-199 pbuE EGP Major facilitator Superfamily
NNECPOPP_03433 2.5e-98 ydhK M Protein of unknown function (DUF1541)
NNECPOPP_03434 7.6e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NNECPOPP_03435 9.5e-83 K Acetyltransferase (GNAT) domain
NNECPOPP_03437 5.2e-65 frataxin S Domain of unknown function (DU1801)
NNECPOPP_03438 5.2e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NNECPOPP_03439 2.1e-123
NNECPOPP_03440 2e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NNECPOPP_03441 4.2e-231 ydhD M Glycosyl hydrolase
NNECPOPP_03442 1.6e-120 ydhC K FCD
NNECPOPP_03443 1.2e-121 ydhB S membrane transporter protein
NNECPOPP_03444 6.3e-208 tcaB EGP Major facilitator Superfamily
NNECPOPP_03445 2.4e-69 ydgJ K Winged helix DNA-binding domain
NNECPOPP_03446 1e-113 drgA C nitroreductase
NNECPOPP_03447 0.0 ydgH S drug exporters of the RND superfamily
NNECPOPP_03448 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
NNECPOPP_03449 1.4e-87 dinB S DinB family
NNECPOPP_03450 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NNECPOPP_03451 1.8e-303 expZ S ABC transporter
NNECPOPP_03452 4.5e-85 yycN 2.3.1.128 K Acetyltransferase
NNECPOPP_03453 4e-51 S DoxX-like family
NNECPOPP_03454 1.9e-93 K Bacterial regulatory proteins, tetR family
NNECPOPP_03455 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NNECPOPP_03456 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NNECPOPP_03457 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
NNECPOPP_03458 9e-122 ydfS S Protein of unknown function (DUF421)
NNECPOPP_03459 3.7e-97 ydfR S Protein of unknown function (DUF421)
NNECPOPP_03461 6.3e-29
NNECPOPP_03462 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NNECPOPP_03463 4.5e-55 traF CO Thioredoxin
NNECPOPP_03464 8.8e-63 mhqP S DoxX
NNECPOPP_03465 7.6e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NNECPOPP_03466 8.1e-111 ydfN C nitroreductase
NNECPOPP_03467 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNECPOPP_03468 9.2e-147 K Bacterial transcription activator, effector binding domain
NNECPOPP_03469 8.5e-117 S Protein of unknown function (DUF554)
NNECPOPP_03470 1.3e-173 S Alpha/beta hydrolase family
NNECPOPP_03472 0.0 ydfJ S drug exporters of the RND superfamily
NNECPOPP_03473 1.6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNECPOPP_03474 2.9e-178 ydfH 2.7.13.3 T Histidine kinase
NNECPOPP_03476 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NNECPOPP_03477 6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NNECPOPP_03478 4.2e-115 ydfE S Flavin reductase like domain
NNECPOPP_03479 7.4e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNECPOPP_03480 1.8e-151 ydfC EG EamA-like transporter family
NNECPOPP_03481 1.1e-90 ydfB J GNAT acetyltransferase
NNECPOPP_03482 4.4e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NNECPOPP_03483 2.8e-57 arsR K transcriptional
NNECPOPP_03484 1.9e-104 ydeS K Transcriptional regulator
NNECPOPP_03485 1.1e-193 ydeR EGP Major facilitator Superfamily
NNECPOPP_03486 5.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NNECPOPP_03487 1.4e-40 K HxlR-like helix-turn-helix
NNECPOPP_03488 6.8e-104 ydeN S Serine hydrolase
NNECPOPP_03489 1.3e-72 maoC I N-terminal half of MaoC dehydratase
NNECPOPP_03490 1.4e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNECPOPP_03491 4.1e-153 ydeK EG -transporter
NNECPOPP_03492 6.8e-85 K Transcriptional regulator C-terminal region
NNECPOPP_03493 1.8e-14 ptsH G PTS HPr component phosphorylation site
NNECPOPP_03494 1.1e-31 S SNARE associated Golgi protein
NNECPOPP_03495 2.2e-106
NNECPOPP_03496 3.9e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NNECPOPP_03497 6.8e-44 ydeH
NNECPOPP_03498 2.1e-217 ydeG EGP Major facilitator superfamily
NNECPOPP_03499 1.7e-262 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNECPOPP_03500 9e-164 ydeE K AraC family transcriptional regulator
NNECPOPP_03501 8.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NNECPOPP_03502 3.3e-166 rhaS5 K AraC-like ligand binding domain
NNECPOPP_03503 1.4e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NNECPOPP_03504 1.5e-77 carD K Transcription factor
NNECPOPP_03505 8.7e-30 cspL K Cold shock
NNECPOPP_03506 4.5e-100 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NNECPOPP_03507 1.2e-39
NNECPOPP_03508 3.4e-33 K Helix-turn-helix XRE-family like proteins
NNECPOPP_03509 5.3e-09 E COG0346 Lactoylglutathione lyase and related lyases
NNECPOPP_03510 5e-47 ydeH
NNECPOPP_03511 6.9e-208 msbA2 3.6.3.44 V ABC transporter
NNECPOPP_03512 7.5e-211 KLT Protein kinase domain
NNECPOPP_03518 3.5e-158 KLT Protein kinase domain
NNECPOPP_03530 8.9e-83 ydcK S Belongs to the SprT family
NNECPOPP_03531 0.0 yhgF K COG2183 Transcriptional accessory protein
NNECPOPP_03532 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NNECPOPP_03533 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNECPOPP_03534 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NNECPOPP_03535 2e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
NNECPOPP_03536 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NNECPOPP_03537 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NNECPOPP_03538 5.2e-57 rsbS T antagonist
NNECPOPP_03539 1.3e-143 rsbR T Positive regulator of sigma-B
NNECPOPP_03540 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NNECPOPP_03541 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NNECPOPP_03542 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNECPOPP_03543 3.2e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NNECPOPP_03544 2.3e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NNECPOPP_03545 3.2e-104 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NNECPOPP_03546 3e-260 ydbT S Membrane
NNECPOPP_03547 2.1e-82 ydbS S Bacterial PH domain
NNECPOPP_03548 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NNECPOPP_03549 1.3e-252 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NNECPOPP_03550 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NNECPOPP_03551 3.9e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NNECPOPP_03552 1.6e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNECPOPP_03553 2.2e-07 S Fur-regulated basic protein A
NNECPOPP_03554 1.1e-18 S Fur-regulated basic protein B
NNECPOPP_03555 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NNECPOPP_03556 2.7e-52 ydbL
NNECPOPP_03557 7.9e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NNECPOPP_03558 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
NNECPOPP_03560 6.3e-180 ydbI S AI-2E family transporter
NNECPOPP_03561 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNECPOPP_03562 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
NNECPOPP_03563 1.4e-295 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NNECPOPP_03564 6.7e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NNECPOPP_03565 2.3e-153 ydbD P Catalase
NNECPOPP_03566 1.3e-59 ydbC S Domain of unknown function (DUF4937
NNECPOPP_03567 2.2e-57 ydbB G Cupin domain
NNECPOPP_03569 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NNECPOPP_03570 1.4e-75 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NNECPOPP_03572 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NNECPOPP_03573 1e-38
NNECPOPP_03574 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NNECPOPP_03575 3.4e-28 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NNECPOPP_03576 4.5e-32 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NNECPOPP_03577 0.0 ydaO E amino acid
NNECPOPP_03578 0.0 ydaN S Bacterial cellulose synthase subunit
NNECPOPP_03579 1.3e-232 ydaM M Glycosyl transferase family group 2
NNECPOPP_03580 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NNECPOPP_03581 2.9e-151 ydaK T Diguanylate cyclase, GGDEF domain
NNECPOPP_03582 2.6e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NNECPOPP_03583 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNECPOPP_03584 2.5e-74 lrpC K Transcriptional regulator
NNECPOPP_03585 3.3e-46 ydzA EGP Major facilitator Superfamily
NNECPOPP_03586 2.7e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NNECPOPP_03587 2e-76 ydaG 1.4.3.5 S general stress protein
NNECPOPP_03588 3.3e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NNECPOPP_03589 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NNECPOPP_03590 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_03591 6.9e-99 ydaC Q Methyltransferase domain
NNECPOPP_03592 2.1e-293 ydaB IQ acyl-CoA ligase
NNECPOPP_03593 0.0 mtlR K transcriptional regulator, MtlR
NNECPOPP_03594 2.8e-176 ydhF S Oxidoreductase
NNECPOPP_03595 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NNECPOPP_03596 9.2e-49 yczJ S biosynthesis
NNECPOPP_03598 1.3e-119 ycsK E anatomical structure formation involved in morphogenesis
NNECPOPP_03599 2.7e-132 kipR K Transcriptional regulator
NNECPOPP_03600 1.5e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NNECPOPP_03601 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NNECPOPP_03602 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
NNECPOPP_03603 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NNECPOPP_03604 4.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
NNECPOPP_03605 6.8e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NNECPOPP_03607 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NNECPOPP_03608 1.8e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NNECPOPP_03609 3.8e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NNECPOPP_03611 2.5e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NNECPOPP_03612 8.1e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NNECPOPP_03613 9.8e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NNECPOPP_03614 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NNECPOPP_03615 3.4e-53
NNECPOPP_03616 2.8e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NNECPOPP_03617 7.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NNECPOPP_03618 1.4e-99 ycnI S protein conserved in bacteria
NNECPOPP_03619 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNECPOPP_03620 6.1e-149 glcU U Glucose uptake
NNECPOPP_03621 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNECPOPP_03622 5.3e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNECPOPP_03623 4.7e-271 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNECPOPP_03624 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NNECPOPP_03625 1.6e-45 ycnE S Monooxygenase
NNECPOPP_03626 1.3e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NNECPOPP_03627 6.5e-154 ycnC K Transcriptional regulator
NNECPOPP_03628 1.2e-250 ycnB EGP Major facilitator Superfamily
NNECPOPP_03629 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NNECPOPP_03630 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NNECPOPP_03631 4.8e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_03632 4.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_03633 6.8e-251 lysC 2.7.2.4 E Belongs to the aspartokinase family
NNECPOPP_03636 3.7e-77 S aspartate phosphatase
NNECPOPP_03637 2.2e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NNECPOPP_03638 2.3e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_03639 1.5e-203 yclI V ABC transporter (permease) YclI
NNECPOPP_03640 1.9e-121 yclH P ABC transporter
NNECPOPP_03641 1.7e-199 gerKB F Spore germination protein
NNECPOPP_03642 6.3e-232 gerKC S spore germination
NNECPOPP_03643 4.6e-278 gerKA EG Spore germination protein
NNECPOPP_03645 4.5e-308 yclG M Pectate lyase superfamily protein
NNECPOPP_03646 4.7e-266 dtpT E amino acid peptide transporter
NNECPOPP_03647 2.7e-157 yclE 3.4.11.5 S Alpha beta hydrolase
NNECPOPP_03648 1.1e-80 yclD
NNECPOPP_03649 4e-39 bsdD 4.1.1.61 S response to toxic substance
NNECPOPP_03650 4.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NNECPOPP_03651 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NNECPOPP_03652 1.2e-160 bsdA K LysR substrate binding domain
NNECPOPP_03653 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NNECPOPP_03654 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NNECPOPP_03655 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NNECPOPP_03656 9.7e-115 yczE S membrane
NNECPOPP_03657 1.7e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NNECPOPP_03658 1.7e-251 ycxD K GntR family transcriptional regulator
NNECPOPP_03659 1.9e-159 ycxC EG EamA-like transporter family
NNECPOPP_03660 2.7e-89 S YcxB-like protein
NNECPOPP_03661 2.2e-224 EGP Major Facilitator Superfamily
NNECPOPP_03662 5.7e-140 srfAD Q thioesterase
NNECPOPP_03663 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NNECPOPP_03664 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_03665 4.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NNECPOPP_03667 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NNECPOPP_03668 1.4e-141 ybbA S Putative esterase
NNECPOPP_03669 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_03670 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNECPOPP_03671 4e-165 feuA P Iron-uptake system-binding protein
NNECPOPP_03672 8.6e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NNECPOPP_03673 3.9e-237 ybbC 3.2.1.52 S protein conserved in bacteria
NNECPOPP_03674 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NNECPOPP_03675 1e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NNECPOPP_03676 4.1e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NNECPOPP_03677 1.4e-150 ybbH K transcriptional
NNECPOPP_03678 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NNECPOPP_03679 1.9e-86 ybbJ J acetyltransferase
NNECPOPP_03680 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NNECPOPP_03686 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_03687 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NNECPOPP_03688 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNECPOPP_03689 9.8e-224 ybbR S protein conserved in bacteria
NNECPOPP_03690 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NNECPOPP_03691 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NNECPOPP_03693 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NNECPOPP_03694 4.4e-120 adaA 3.2.2.21 K Transcriptional regulator
NNECPOPP_03695 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNECPOPP_03696 4.7e-277 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NNECPOPP_03697 0.0 ybcC S Belongs to the UPF0753 family
NNECPOPP_03698 2.9e-93 can 4.2.1.1 P carbonic anhydrase
NNECPOPP_03700 8.7e-47
NNECPOPP_03701 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NNECPOPP_03703 5.1e-50 ybzH K Helix-turn-helix domain
NNECPOPP_03704 2.9e-202 ybcL EGP Major facilitator Superfamily
NNECPOPP_03706 5.1e-174 L Protein of unknown function (DUF2813)
NNECPOPP_03707 2.8e-104 pcrA1 3.6.4.12 L UvrD-like helicase C-terminal domain
NNECPOPP_03708 2e-39 C HEAT repeats
NNECPOPP_03709 5.8e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NNECPOPP_03710 4.5e-123 T Transcriptional regulatory protein, C terminal
NNECPOPP_03711 8.5e-171 T His Kinase A (phospho-acceptor) domain
NNECPOPP_03712 8.8e-139 KLT Protein tyrosine kinase
NNECPOPP_03713 1.7e-151 ybdN
NNECPOPP_03714 9.8e-214 ybdO S Domain of unknown function (DUF4885)
NNECPOPP_03715 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NNECPOPP_03716 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
NNECPOPP_03717 4.9e-30 ybxH S Family of unknown function (DUF5370)
NNECPOPP_03718 1.5e-149 ybxI 3.5.2.6 V beta-lactamase
NNECPOPP_03719 1.1e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NNECPOPP_03720 4.9e-41 ybyB
NNECPOPP_03721 1.8e-290 ybeC E amino acid
NNECPOPP_03722 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NNECPOPP_03723 1.2e-257 glpT G -transporter
NNECPOPP_03724 5.5e-34 S Protein of unknown function (DUF2651)
NNECPOPP_03725 9.7e-169 ybfA 3.4.15.5 K FR47-like protein
NNECPOPP_03726 1.5e-220 ybfB G COG0477 Permeases of the major facilitator superfamily
NNECPOPP_03727 2.2e-160 ybfH EG EamA-like transporter family
NNECPOPP_03728 2.3e-145 msmR K AraC-like ligand binding domain
NNECPOPP_03729 8e-148 draG 3.2.2.24 O ADP-ribosylglycohydrolase
NNECPOPP_03730 1.3e-77 M nucleic acid phosphodiester bond hydrolysis
NNECPOPP_03731 2.1e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NNECPOPP_03732 1.7e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NNECPOPP_03734 4e-167 S Alpha/beta hydrolase family
NNECPOPP_03735 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNECPOPP_03736 2.7e-85 ybfM S SNARE associated Golgi protein
NNECPOPP_03737 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NNECPOPP_03738 3e-44 ybfN
NNECPOPP_03739 3.9e-192 yceA S Belongs to the UPF0176 family
NNECPOPP_03740 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNECPOPP_03741 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NNECPOPP_03742 6.3e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNECPOPP_03743 4.9e-128 K UTRA
NNECPOPP_03745 5.9e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NNECPOPP_03746 7e-259 mmuP E amino acid
NNECPOPP_03747 3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NNECPOPP_03748 1.3e-252 agcS E Sodium alanine symporter
NNECPOPP_03749 4.7e-177 glsA 3.5.1.2 E Belongs to the glutaminase family
NNECPOPP_03750 1.2e-214 phoQ 2.7.13.3 T Histidine kinase
NNECPOPP_03751 1.7e-168 glnL T Regulator
NNECPOPP_03752 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NNECPOPP_03753 5.8e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNECPOPP_03754 2.7e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NNECPOPP_03755 6.1e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NNECPOPP_03756 1.9e-124 ycbG K FCD
NNECPOPP_03757 4.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
NNECPOPP_03758 1.8e-175 ycbJ S Macrolide 2'-phosphotransferase
NNECPOPP_03759 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NNECPOPP_03760 4.5e-169 eamA1 EG spore germination
NNECPOPP_03761 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNECPOPP_03762 2.2e-168 T PhoQ Sensor
NNECPOPP_03763 5.9e-166 ycbN V ABC transporter, ATP-binding protein
NNECPOPP_03764 2.5e-113 S ABC-2 family transporter protein
NNECPOPP_03765 4.1e-52 ycbP S Protein of unknown function (DUF2512)
NNECPOPP_03766 1.1e-77 sleB 3.5.1.28 M Cell wall
NNECPOPP_03767 3.1e-133 ycbR T vWA found in TerF C terminus
NNECPOPP_03768 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NNECPOPP_03769 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NNECPOPP_03770 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NNECPOPP_03771 4.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NNECPOPP_03772 5.1e-204 ycbU E Selenocysteine lyase
NNECPOPP_03773 3e-225 lmrB EGP the major facilitator superfamily
NNECPOPP_03774 1.3e-99 yxaF K Transcriptional regulator
NNECPOPP_03775 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NNECPOPP_03776 2.1e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NNECPOPP_03777 4.5e-59 S RDD family
NNECPOPP_03778 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
NNECPOPP_03779 6.8e-157 2.7.13.3 T GHKL domain
NNECPOPP_03780 2e-126 lytR_2 T LytTr DNA-binding domain
NNECPOPP_03781 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NNECPOPP_03782 2.2e-202 natB CP ABC-2 family transporter protein
NNECPOPP_03783 1e-173 yccK C Aldo keto reductase
NNECPOPP_03784 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NNECPOPP_03785 5.7e-277 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_03786 2.5e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NNECPOPP_03787 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
NNECPOPP_03788 1.2e-173 S response regulator aspartate phosphatase
NNECPOPP_03789 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
NNECPOPP_03790 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NNECPOPP_03791 2.8e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
NNECPOPP_03792 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NNECPOPP_03793 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NNECPOPP_03794 6.1e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNECPOPP_03795 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NNECPOPP_03796 8.2e-105 yceD T proteins involved in stress response, homologs of TerZ and
NNECPOPP_03797 3.9e-107 yceE T proteins involved in stress response, homologs of TerZ and
NNECPOPP_03798 1.4e-136 terC P Protein of unknown function (DUF475)
NNECPOPP_03799 0.0 yceG S Putative component of 'biosynthetic module'
NNECPOPP_03800 2e-192 yceH P Belongs to the TelA family
NNECPOPP_03801 1.1e-217 naiP P Uncharacterised MFS-type transporter YbfB
NNECPOPP_03802 4.7e-208 yceJ EGP Uncharacterised MFS-type transporter YbfB
NNECPOPP_03803 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NNECPOPP_03804 1.9e-228 proV 3.6.3.32 E glycine betaine
NNECPOPP_03805 1.3e-127 opuAB P glycine betaine
NNECPOPP_03806 1.5e-163 opuAC E glycine betaine
NNECPOPP_03807 1.9e-217 amhX S amidohydrolase
NNECPOPP_03808 8.7e-257 ycgA S Membrane
NNECPOPP_03809 4.1e-81 ycgB
NNECPOPP_03810 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NNECPOPP_03811 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NNECPOPP_03812 1.5e-289 lctP C L-lactate permease
NNECPOPP_03813 3.6e-261 mdr EGP Major facilitator Superfamily
NNECPOPP_03814 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NNECPOPP_03815 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NNECPOPP_03816 9.2e-149 yqcI S YqcI/YcgG family
NNECPOPP_03817 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NNECPOPP_03818 9.3e-112 ycgI S Domain of unknown function (DUF1989)
NNECPOPP_03819 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NNECPOPP_03820 2.1e-108 tmrB S AAA domain
NNECPOPP_03821 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NNECPOPP_03822 9e-144 yafE Q ubiE/COQ5 methyltransferase family
NNECPOPP_03823 6.7e-176 oxyR3 K LysR substrate binding domain
NNECPOPP_03824 2.5e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NNECPOPP_03825 2.4e-144 ycgL S Predicted nucleotidyltransferase
NNECPOPP_03826 5.1e-170 ycgM E Proline dehydrogenase
NNECPOPP_03827 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NNECPOPP_03828 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNECPOPP_03829 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NNECPOPP_03830 2.2e-146 ycgQ S membrane
NNECPOPP_03831 2.7e-139 ycgR S permeases
NNECPOPP_03832 6.9e-161 I alpha/beta hydrolase fold
NNECPOPP_03833 6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NNECPOPP_03834 6.6e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NNECPOPP_03835 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
NNECPOPP_03836 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NNECPOPP_03837 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNECPOPP_03838 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NNECPOPP_03839 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
NNECPOPP_03840 4.2e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NNECPOPP_03841 4.2e-101 yciB M ErfK YbiS YcfS YnhG
NNECPOPP_03842 3.3e-225 yciC S GTPases (G3E family)
NNECPOPP_03843 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NNECPOPP_03844 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NNECPOPP_03845 7.8e-52 yckD S Protein of unknown function (DUF2680)
NNECPOPP_03846 2.6e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NNECPOPP_03847 1.1e-68 nin S Competence protein J (ComJ)
NNECPOPP_03848 3.9e-70 nucA M Deoxyribonuclease NucA/NucB
NNECPOPP_03849 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
NNECPOPP_03850 4.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NNECPOPP_03851 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NNECPOPP_03852 1.3e-63 hxlR K transcriptional
NNECPOPP_03853 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_03854 1.5e-88 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_03856 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NNECPOPP_03857 1.9e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNECPOPP_03858 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NNECPOPP_03859 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NNECPOPP_03861 1.9e-15 yycC K YycC-like protein
NNECPOPP_03862 4.6e-219 yeaN P COG2807 Cyanate permease
NNECPOPP_03863 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NNECPOPP_03864 2.2e-73 rplI J binds to the 23S rRNA
NNECPOPP_03865 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NNECPOPP_03866 8.3e-160 yybS S membrane
NNECPOPP_03868 3.3e-83 cotF M Spore coat protein
NNECPOPP_03869 1.7e-66 ydeP3 K Transcriptional regulator
NNECPOPP_03870 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NNECPOPP_03871 1.2e-58
NNECPOPP_03873 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NNECPOPP_03874 4.3e-111 K TipAS antibiotic-recognition domain
NNECPOPP_03875 2.9e-121
NNECPOPP_03876 6.5e-66 yybH S SnoaL-like domain
NNECPOPP_03877 2e-120 yybG S Pentapeptide repeat-containing protein
NNECPOPP_03878 4.1e-215 ynfM EGP Major facilitator Superfamily
NNECPOPP_03879 1.1e-164 yybE K Transcriptional regulator
NNECPOPP_03880 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
NNECPOPP_03881 9.5e-75 yybC
NNECPOPP_03882 2.1e-125 S Metallo-beta-lactamase superfamily
NNECPOPP_03883 2.1e-76 yybA 2.3.1.57 K transcriptional
NNECPOPP_03884 2.7e-71 yjcF S Acetyltransferase (GNAT) domain
NNECPOPP_03885 2.5e-96 yyaS S Membrane
NNECPOPP_03886 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
NNECPOPP_03887 3.5e-66 yyaQ S YjbR
NNECPOPP_03888 1.4e-104 yyaP 1.5.1.3 H RibD C-terminal domain
NNECPOPP_03890 5.2e-68 O AAA domain (Cdc48 subfamily)
NNECPOPP_03891 7e-35
NNECPOPP_03892 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NNECPOPP_03893 1.5e-166 yyaK S CAAX protease self-immunity
NNECPOPP_03894 6.1e-244 EGP Major facilitator superfamily
NNECPOPP_03895 9.6e-95 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NNECPOPP_03896 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNECPOPP_03897 2.1e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NNECPOPP_03898 2.2e-142 xth 3.1.11.2 L exodeoxyribonuclease III
NNECPOPP_03899 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NNECPOPP_03900 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NNECPOPP_03901 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NNECPOPP_03902 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NNECPOPP_03903 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNECPOPP_03904 2.3e-33 yyzM S protein conserved in bacteria
NNECPOPP_03905 8.1e-177 yyaD S Membrane
NNECPOPP_03906 2.8e-111 yyaC S Sporulation protein YyaC
NNECPOPP_03907 2.1e-149 spo0J K Belongs to the ParB family
NNECPOPP_03908 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NNECPOPP_03909 1.3e-73 S Bacterial PH domain
NNECPOPP_03910 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NNECPOPP_03911 9.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NNECPOPP_03912 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NNECPOPP_03913 2.2e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NNECPOPP_03914 7.2e-107 jag S single-stranded nucleic acid binding R3H
NNECPOPP_03915 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNECPOPP_03916 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NNECPOPP_03917 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NNECPOPP_03918 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NNECPOPP_03919 2.4e-33 yaaA S S4 domain
NNECPOPP_03920 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NNECPOPP_03921 1.8e-37 yaaB S Domain of unknown function (DUF370)
NNECPOPP_03922 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNECPOPP_03923 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNECPOPP_03924 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NNECPOPP_03925 1.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNECPOPP_03926 4.1e-30 yazB K transcriptional
NNECPOPP_03927 7.9e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NNECPOPP_03928 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NNECPOPP_03929 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NNECPOPP_03930 6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NNECPOPP_03931 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NNECPOPP_03932 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NNECPOPP_03933 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NNECPOPP_03934 3.4e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NNECPOPP_03935 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NNECPOPP_03936 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NNECPOPP_03937 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NNECPOPP_03938 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NNECPOPP_03939 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NNECPOPP_03940 4.5e-183 KLT serine threonine protein kinase
NNECPOPP_03941 4.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NNECPOPP_03942 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NNECPOPP_03945 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NNECPOPP_03946 1.1e-44 divIC D Septum formation initiator
NNECPOPP_03947 4.3e-107 yabQ S spore cortex biosynthesis protein
NNECPOPP_03948 1.5e-49 yabP S Sporulation protein YabP
NNECPOPP_03949 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NNECPOPP_03950 3.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NNECPOPP_03951 2.2e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNECPOPP_03952 1.5e-92 spoVT K stage V sporulation protein
NNECPOPP_03953 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NNECPOPP_03954 6.9e-39 yabK S Peptide ABC transporter permease
NNECPOPP_03955 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NNECPOPP_03956 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NNECPOPP_03957 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNECPOPP_03958 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NNECPOPP_03959 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NNECPOPP_03960 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NNECPOPP_03961 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NNECPOPP_03962 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NNECPOPP_03963 8.3e-27 sspF S DNA topological change
NNECPOPP_03964 7.8e-39 veg S protein conserved in bacteria
NNECPOPP_03965 1.8e-135 yabG S peptidase
NNECPOPP_03966 4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NNECPOPP_03967 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NNECPOPP_03968 2e-167 rpfB GH23 T protein conserved in bacteria
NNECPOPP_03969 4.5e-143 tatD L hydrolase, TatD
NNECPOPP_03970 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NNECPOPP_03971 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NNECPOPP_03972 3.5e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NNECPOPP_03973 1.5e-49 yazA L endonuclease containing a URI domain
NNECPOPP_03974 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NNECPOPP_03975 4.8e-31 yabA L Involved in initiation control of chromosome replication
NNECPOPP_03976 6.1e-146 yaaT S stage 0 sporulation protein
NNECPOPP_03977 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NNECPOPP_03978 3.4e-71 yaaR S protein conserved in bacteria
NNECPOPP_03979 2.2e-54 yaaQ S protein conserved in bacteria
NNECPOPP_03980 5.8e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NNECPOPP_03981 1.5e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NNECPOPP_03982 8.4e-202 yaaN P Belongs to the TelA family
NNECPOPP_03983 4.4e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NNECPOPP_03984 3.4e-31 csfB S Inhibitor of sigma-G Gin
NNECPOPP_03985 1e-82 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NNECPOPP_03986 4.8e-217 mepA V Multidrug transporter MatE
NNECPOPP_03987 3.6e-112 tetR3 K Transcriptional regulator
NNECPOPP_03988 2.8e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNECPOPP_03989 2.4e-95 adk 2.7.4.3 F adenylate kinase activity
NNECPOPP_03990 5.9e-89 K Transcriptional regulator PadR-like family
NNECPOPP_03991 2.6e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
NNECPOPP_03993 6.1e-42 xkdC L IstB-like ATP binding protein
NNECPOPP_03995 1.6e-73 rusA L Endodeoxyribonuclease RusA
NNECPOPP_03996 1.4e-30 yqaO S Phage-like element PBSX protein XtrA
NNECPOPP_03999 1.5e-41 L Transposase
NNECPOPP_04000 3.7e-26 cotD S Inner spore coat protein D
NNECPOPP_04002 1.5e-29 yqaS L DNA packaging
NNECPOPP_04003 1.2e-41 yqaS L DNA packaging
NNECPOPP_04004 1.3e-27 S phage terminase, large subunit
NNECPOPP_04005 1.5e-86 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NNECPOPP_04006 2.5e-119 EGP Necrosis inducing protein (NPP1)
NNECPOPP_04007 4.6e-82 S SMI1-KNR4 cell-wall
NNECPOPP_04008 3.9e-307 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NNECPOPP_04009 4.4e-28
NNECPOPP_04011 1.1e-60 S TraX protein
NNECPOPP_04013 8.4e-130 S Aspartate phosphatase response regulator
NNECPOPP_04019 6.3e-33 L Phage integrase, N-terminal SAM-like domain
NNECPOPP_04020 6.5e-30 L Phage integrase, N-terminal SAM-like domain
NNECPOPP_04021 5.4e-16 xkdA E IrrE N-terminal-like domain
NNECPOPP_04022 9.6e-25
NNECPOPP_04023 4.7e-49 bldD K domain, Protein
NNECPOPP_04024 6.1e-11 K Helix-turn-helix XRE-family like proteins
NNECPOPP_04025 4.7e-09 S Helix-turn-helix domain
NNECPOPP_04026 1.2e-11
NNECPOPP_04027 3.3e-17
NNECPOPP_04028 1.2e-12 bet L RecT family
NNECPOPP_04029 8.9e-31
NNECPOPP_04032 2.4e-35
NNECPOPP_04037 4.8e-56 K DNA binding
NNECPOPP_04038 1.2e-122 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NNECPOPP_04039 6.2e-17
NNECPOPP_04041 3.2e-29
NNECPOPP_04042 4.4e-18 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NNECPOPP_04043 1.7e-15
NNECPOPP_04044 2e-40
NNECPOPP_04045 2.1e-185 A Pre-toxin TG
NNECPOPP_04046 5.7e-25
NNECPOPP_04047 9.3e-59
NNECPOPP_04048 2e-08
NNECPOPP_04052 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NNECPOPP_04053 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NNECPOPP_04054 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NNECPOPP_04055 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NNECPOPP_04056 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNECPOPP_04057 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NNECPOPP_04058 1.9e-95 yaaI Q COG1335 Amidases related to nicotinamidase
NNECPOPP_04059 4.9e-211 yaaH M Glycoside Hydrolase Family
NNECPOPP_04060 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NNECPOPP_04061 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NNECPOPP_04062 1.3e-09
NNECPOPP_04063 6.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NNECPOPP_04064 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NNECPOPP_04065 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NNECPOPP_04066 5.8e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NNECPOPP_04067 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NNECPOPP_04068 1e-181 yaaC S YaaC-like Protein
NNECPOPP_04069 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_04070 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNECPOPP_04071 8.4e-168 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)