ORF_ID e_value Gene_name EC_number CAZy COGs Description
EJEMHCOK_00001 2.3e-23 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EJEMHCOK_00002 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
EJEMHCOK_00003 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EJEMHCOK_00004 4.5e-283 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EJEMHCOK_00005 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EJEMHCOK_00006 2.7e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EJEMHCOK_00007 4.3e-226 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
EJEMHCOK_00008 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJEMHCOK_00009 2e-294 murC 6.3.2.8 M Belongs to the MurCDEF family
EJEMHCOK_00010 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
EJEMHCOK_00011 4.9e-37
EJEMHCOK_00013 6.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EJEMHCOK_00014 1.3e-235 G Major Facilitator Superfamily
EJEMHCOK_00015 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
EJEMHCOK_00016 2.8e-224 GK ROK family
EJEMHCOK_00017 4.9e-131 cutC P Participates in the control of copper homeostasis
EJEMHCOK_00018 3.5e-216 GK ROK family
EJEMHCOK_00019 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EJEMHCOK_00020 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
EJEMHCOK_00021 1.5e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
EJEMHCOK_00022 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
EJEMHCOK_00023 1.9e-190 dppC EP Binding-protein-dependent transport system inner membrane component
EJEMHCOK_00024 0.0 P Belongs to the ABC transporter superfamily
EJEMHCOK_00025 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
EJEMHCOK_00026 9.6e-97 3.6.1.55 F NUDIX domain
EJEMHCOK_00028 4.5e-286 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
EJEMHCOK_00029 0.0 smc D Required for chromosome condensation and partitioning
EJEMHCOK_00030 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
EJEMHCOK_00031 2.8e-243 yxbA 6.3.1.12 S ATP-grasp
EJEMHCOK_00032 1.1e-228 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
EJEMHCOK_00033 6.8e-192 V Acetyltransferase (GNAT) domain
EJEMHCOK_00034 2.6e-297 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EJEMHCOK_00035 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
EJEMHCOK_00036 2e-64
EJEMHCOK_00037 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
EJEMHCOK_00038 3.3e-34 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EJEMHCOK_00039 2.4e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EJEMHCOK_00040 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EJEMHCOK_00041 6.8e-133 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
EJEMHCOK_00042 6.6e-08 S Spermine/spermidine synthase domain
EJEMHCOK_00043 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EJEMHCOK_00044 2.1e-25 rpmI J Ribosomal protein L35
EJEMHCOK_00045 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EJEMHCOK_00046 2.9e-179 xerD D recombinase XerD
EJEMHCOK_00047 7e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
EJEMHCOK_00048 1.4e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EJEMHCOK_00049 2.5e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EJEMHCOK_00050 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
EJEMHCOK_00051 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EJEMHCOK_00052 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
EJEMHCOK_00053 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
EJEMHCOK_00054 2.6e-236 iscS1 2.8.1.7 E Aminotransferase class-V
EJEMHCOK_00055 0.0 typA T Elongation factor G C-terminus
EJEMHCOK_00056 5.5e-92
EJEMHCOK_00057 5e-198 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
EJEMHCOK_00058 3.2e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
EJEMHCOK_00059 7.3e-42
EJEMHCOK_00060 4.3e-186 xerC D Belongs to the 'phage' integrase family. XerC subfamily
EJEMHCOK_00061 3e-176 appB EP Binding-protein-dependent transport system inner membrane component
EJEMHCOK_00062 8.7e-165 dppC EP N-terminal TM domain of oligopeptide transport permease C
EJEMHCOK_00063 0.0 oppD P Belongs to the ABC transporter superfamily
EJEMHCOK_00064 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
EJEMHCOK_00065 8.2e-276 pepC 3.4.22.40 E Peptidase C1-like family
EJEMHCOK_00066 2.2e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
EJEMHCOK_00067 3.2e-139 S Protein of unknown function (DUF3710)
EJEMHCOK_00068 1.7e-121 S Protein of unknown function (DUF3159)
EJEMHCOK_00069 4.8e-257 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EJEMHCOK_00070 8.3e-108
EJEMHCOK_00071 0.0 ctpE P E1-E2 ATPase
EJEMHCOK_00072 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EJEMHCOK_00074 2.5e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
EJEMHCOK_00075 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
EJEMHCOK_00076 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EJEMHCOK_00077 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EJEMHCOK_00078 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EJEMHCOK_00079 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EJEMHCOK_00080 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EJEMHCOK_00081 4.7e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
EJEMHCOK_00082 0.0 arc O AAA ATPase forming ring-shaped complexes
EJEMHCOK_00083 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
EJEMHCOK_00084 3e-161 hisN 3.1.3.25 G Inositol monophosphatase family
EJEMHCOK_00085 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
EJEMHCOK_00086 6.5e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EJEMHCOK_00087 8.1e-42 hup L Belongs to the bacterial histone-like protein family
EJEMHCOK_00088 0.0 S Lysylphosphatidylglycerol synthase TM region
EJEMHCOK_00089 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
EJEMHCOK_00090 1.4e-289 S PGAP1-like protein
EJEMHCOK_00092 7.2e-75
EJEMHCOK_00093 1.6e-148 S von Willebrand factor (vWF) type A domain
EJEMHCOK_00094 2.3e-190 S von Willebrand factor (vWF) type A domain
EJEMHCOK_00095 6.4e-94
EJEMHCOK_00096 6.1e-177 S Protein of unknown function DUF58
EJEMHCOK_00097 1e-196 moxR S ATPase family associated with various cellular activities (AAA)
EJEMHCOK_00098 1.1e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EJEMHCOK_00099 5.8e-71 S LytR cell envelope-related transcriptional attenuator
EJEMHCOK_00100 1.9e-43 cspA K 'Cold-shock' DNA-binding domain
EJEMHCOK_00101 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EJEMHCOK_00102 1.7e-10 S Proteins of 100 residues with WXG
EJEMHCOK_00103 4.9e-162
EJEMHCOK_00104 1.6e-134 KT Response regulator receiver domain protein
EJEMHCOK_00105 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EJEMHCOK_00106 1e-66 cspB K 'Cold-shock' DNA-binding domain
EJEMHCOK_00107 3e-193 S Protein of unknown function (DUF3027)
EJEMHCOK_00108 8e-185 uspA T Belongs to the universal stress protein A family
EJEMHCOK_00109 0.0 clpC O ATPase family associated with various cellular activities (AAA)
EJEMHCOK_00113 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
EJEMHCOK_00114 8.7e-262 hisS 6.1.1.21 J Histidyl-tRNA synthetase
EJEMHCOK_00115 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EJEMHCOK_00116 1.4e-84 K helix_turn_helix, Lux Regulon
EJEMHCOK_00117 8.2e-93 S Aminoacyl-tRNA editing domain
EJEMHCOK_00118 2e-138 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
EJEMHCOK_00119 2.8e-146 gluB ET Belongs to the bacterial solute-binding protein 3 family
EJEMHCOK_00120 1.5e-110 gluC E Binding-protein-dependent transport system inner membrane component
EJEMHCOK_00121 1.1e-198 gluD E Binding-protein-dependent transport system inner membrane component
EJEMHCOK_00122 3.9e-193 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
EJEMHCOK_00123 0.0 L DEAD DEAH box helicase
EJEMHCOK_00124 8.5e-257 rarA L Recombination factor protein RarA
EJEMHCOK_00126 2.6e-256 EGP Major facilitator Superfamily
EJEMHCOK_00127 0.0 ecfA GP ABC transporter, ATP-binding protein
EJEMHCOK_00128 4.3e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EJEMHCOK_00129 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
EJEMHCOK_00130 2e-213 E Aminotransferase class I and II
EJEMHCOK_00131 9.9e-138 bioM P ATPases associated with a variety of cellular activities
EJEMHCOK_00132 9.8e-76 2.8.2.22 S Arylsulfotransferase Ig-like domain
EJEMHCOK_00133 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EJEMHCOK_00134 0.0 S Tetratricopeptide repeat
EJEMHCOK_00135 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EJEMHCOK_00136 6.3e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EJEMHCOK_00137 8.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
EJEMHCOK_00138 2e-86 int L Phage integrase, N-terminal SAM-like domain
EJEMHCOK_00139 4.8e-115 L DNA restriction-modification system
EJEMHCOK_00140 7.8e-33 3.1.21.4 L Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
EJEMHCOK_00141 4.4e-78 S GIY-YIG catalytic domain
EJEMHCOK_00145 5.5e-33 traSA D FtsK/SpoIIIE family
EJEMHCOK_00147 4.7e-10
EJEMHCOK_00148 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
EJEMHCOK_00149 9.4e-144 S Domain of unknown function (DUF4191)
EJEMHCOK_00150 8.9e-281 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJEMHCOK_00151 5.5e-104 S Protein of unknown function (DUF3043)
EJEMHCOK_00152 8.8e-259 argE E Peptidase dimerisation domain
EJEMHCOK_00153 5.8e-134 V N-Acetylmuramoyl-L-alanine amidase
EJEMHCOK_00154 1.1e-34 V N-Acetylmuramoyl-L-alanine amidase
EJEMHCOK_00155 3.7e-143 ytrE V ATPases associated with a variety of cellular activities
EJEMHCOK_00156 1.2e-194
EJEMHCOK_00157 3.9e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
EJEMHCOK_00158 0.0 S Uncharacterised protein family (UPF0182)
EJEMHCOK_00159 4.3e-208 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EJEMHCOK_00160 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EJEMHCOK_00161 3.1e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
EJEMHCOK_00163 4e-80 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EJEMHCOK_00164 1.9e-197 GM GDP-mannose 4,6 dehydratase
EJEMHCOK_00165 3.6e-151 GM ABC-2 type transporter
EJEMHCOK_00166 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
EJEMHCOK_00167 2.7e-97 2.3.1.183 M Acetyltransferase (GNAT) domain
EJEMHCOK_00168 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EJEMHCOK_00169 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EJEMHCOK_00170 2.2e-298 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
EJEMHCOK_00171 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
EJEMHCOK_00172 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EJEMHCOK_00173 2.5e-101 divIC D Septum formation initiator
EJEMHCOK_00174 2.6e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
EJEMHCOK_00175 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
EJEMHCOK_00177 6.1e-97
EJEMHCOK_00178 5.1e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
EJEMHCOK_00179 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
EJEMHCOK_00180 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EJEMHCOK_00182 2e-142 yplQ S Haemolysin-III related
EJEMHCOK_00183 7.3e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EJEMHCOK_00184 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
EJEMHCOK_00185 0.0 D FtsK/SpoIIIE family
EJEMHCOK_00186 2.7e-24 K Cell envelope-related transcriptional attenuator domain
EJEMHCOK_00187 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
EJEMHCOK_00188 0.0 S Glycosyl transferase, family 2
EJEMHCOK_00189 2e-259
EJEMHCOK_00190 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
EJEMHCOK_00191 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
EJEMHCOK_00192 7.7e-129 ctsW S Phosphoribosyl transferase domain
EJEMHCOK_00193 3.6e-72 rulA 3.4.21.88 KT Peptidase S24-like
EJEMHCOK_00194 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EJEMHCOK_00195 1.9e-127 T Response regulator receiver domain protein
EJEMHCOK_00196 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EJEMHCOK_00197 5.1e-102 carD K CarD-like/TRCF domain
EJEMHCOK_00198 8.5e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EJEMHCOK_00199 4.3e-139 znuB U ABC 3 transport family
EJEMHCOK_00200 2.8e-165 znuC P ATPases associated with a variety of cellular activities
EJEMHCOK_00201 2.5e-173 P Zinc-uptake complex component A periplasmic
EJEMHCOK_00202 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJEMHCOK_00203 2.8e-242 rpsA J Ribosomal protein S1
EJEMHCOK_00204 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EJEMHCOK_00205 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EJEMHCOK_00206 1.1e-178 terC P Integral membrane protein, TerC family
EJEMHCOK_00207 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
EJEMHCOK_00208 3.3e-109 aspA 3.6.1.13 L NUDIX domain
EJEMHCOK_00210 9.2e-120 pdtaR T Response regulator receiver domain protein
EJEMHCOK_00211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJEMHCOK_00212 6.5e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
EJEMHCOK_00213 1.9e-127 3.6.1.13 L NUDIX domain
EJEMHCOK_00214 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EJEMHCOK_00215 1.7e-217 ykiI
EJEMHCOK_00217 4.2e-135 L Phage integrase family
EJEMHCOK_00218 2.9e-108 3.4.13.21 E Peptidase family S51
EJEMHCOK_00219 2.9e-276 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EJEMHCOK_00220 1.3e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EJEMHCOK_00221 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EJEMHCOK_00222 1e-281 XK27_07020 S Domain of unknown function (DUF1846)
EJEMHCOK_00223 1.7e-122
EJEMHCOK_00225 9.9e-112 ysdA S Protein of unknown function (DUF1294)
EJEMHCOK_00226 1.2e-27
EJEMHCOK_00227 4.4e-51
EJEMHCOK_00229 1.1e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EJEMHCOK_00230 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
EJEMHCOK_00231 3.4e-189 pit P Phosphate transporter family
EJEMHCOK_00232 1.1e-115 MA20_27875 P Protein of unknown function DUF47
EJEMHCOK_00233 1.7e-120 K helix_turn_helix, Lux Regulon
EJEMHCOK_00234 6e-233 T Histidine kinase
EJEMHCOK_00235 9.9e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
EJEMHCOK_00236 2e-183 V ATPases associated with a variety of cellular activities
EJEMHCOK_00237 2.9e-224 V ABC-2 family transporter protein
EJEMHCOK_00238 1.1e-251 V ABC-2 family transporter protein
EJEMHCOK_00239 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
EJEMHCOK_00240 6.3e-196 L Transposase and inactivated derivatives IS30 family
EJEMHCOK_00242 1.2e-85
EJEMHCOK_00243 1.2e-64 D MobA/MobL family
EJEMHCOK_00244 4.3e-47 L Transposase
EJEMHCOK_00245 5.9e-182 tnp7109-21 L Integrase core domain
EJEMHCOK_00246 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
EJEMHCOK_00247 1.1e-40
EJEMHCOK_00248 1.9e-112 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
EJEMHCOK_00250 2.9e-93 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EJEMHCOK_00251 1.2e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EJEMHCOK_00253 1.1e-240 pbuX F Permease family
EJEMHCOK_00254 3e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EJEMHCOK_00255 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
EJEMHCOK_00256 0.0 pcrA 3.6.4.12 L DNA helicase
EJEMHCOK_00257 8.2e-64 S Domain of unknown function (DUF4418)
EJEMHCOK_00258 1.9e-212 V FtsX-like permease family
EJEMHCOK_00259 1.3e-127 lolD V ABC transporter
EJEMHCOK_00260 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EJEMHCOK_00261 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
EJEMHCOK_00262 3.3e-135 pgm3 G Phosphoglycerate mutase family
EJEMHCOK_00263 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
EJEMHCOK_00264 1.1e-36
EJEMHCOK_00265 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EJEMHCOK_00266 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EJEMHCOK_00267 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EJEMHCOK_00268 1.3e-47 3.4.23.43 S Type IV leader peptidase family
EJEMHCOK_00269 6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EJEMHCOK_00270 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EJEMHCOK_00271 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
EJEMHCOK_00272 3.4e-15
EJEMHCOK_00273 1.7e-120 K helix_turn_helix, Lux Regulon
EJEMHCOK_00274 2.6e-07 3.4.22.70 M Sortase family
EJEMHCOK_00275 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EJEMHCOK_00276 3.6e-290 sufB O FeS assembly protein SufB
EJEMHCOK_00277 1.3e-232 sufD O FeS assembly protein SufD
EJEMHCOK_00278 4.2e-144 sufC O FeS assembly ATPase SufC
EJEMHCOK_00279 1.7e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EJEMHCOK_00280 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
EJEMHCOK_00281 1.2e-108 yitW S Iron-sulfur cluster assembly protein
EJEMHCOK_00282 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EJEMHCOK_00283 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
EJEMHCOK_00285 2.1e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EJEMHCOK_00286 7.5e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
EJEMHCOK_00287 5.8e-197 phoH T PhoH-like protein
EJEMHCOK_00288 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EJEMHCOK_00289 2.4e-251 corC S CBS domain
EJEMHCOK_00290 5.1e-187 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EJEMHCOK_00291 1.4e-264 fadD 6.2.1.3 I AMP-binding enzyme
EJEMHCOK_00292 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
EJEMHCOK_00293 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
EJEMHCOK_00294 5.2e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EJEMHCOK_00295 9.7e-191 S alpha beta
EJEMHCOK_00296 1.7e-94 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EJEMHCOK_00297 1.8e-225 ilvE 2.6.1.42 E Amino-transferase class IV
EJEMHCOK_00298 8.2e-74 3.1.4.37 T RNA ligase
EJEMHCOK_00299 1.2e-135 S UPF0126 domain
EJEMHCOK_00300 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
EJEMHCOK_00301 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EJEMHCOK_00302 1.5e-242 hemN H Involved in the biosynthesis of porphyrin-containing compound
EJEMHCOK_00303 4e-13 S Membrane
EJEMHCOK_00304 2.2e-285 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
EJEMHCOK_00305 0.0 tetP J Elongation factor G, domain IV
EJEMHCOK_00306 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
EJEMHCOK_00307 1e-303 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
EJEMHCOK_00308 3.6e-82
EJEMHCOK_00309 5.1e-245 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
EJEMHCOK_00310 5.7e-163 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
EJEMHCOK_00311 1.7e-151 ybeM S Carbon-nitrogen hydrolase
EJEMHCOK_00312 7e-53 S Sel1-like repeats.
EJEMHCOK_00313 2.6e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EJEMHCOK_00314 1.4e-60 S Short C-terminal domain
EJEMHCOK_00315 9.8e-94 L Transposase
EJEMHCOK_00316 1.6e-28
EJEMHCOK_00317 8.4e-222 L Uncharacterized conserved protein (DUF2075)
EJEMHCOK_00318 2.8e-28
EJEMHCOK_00319 7.7e-98 rarD 3.4.17.13 E Rard protein
EJEMHCOK_00320 8.8e-178 I alpha/beta hydrolase fold
EJEMHCOK_00321 7.4e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EJEMHCOK_00322 9e-101 sixA 3.6.1.55 T Phosphoglycerate mutase family
EJEMHCOK_00323 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EJEMHCOK_00324 2.1e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
EJEMHCOK_00326 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
EJEMHCOK_00327 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EJEMHCOK_00328 7.7e-238 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EJEMHCOK_00329 8.9e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
EJEMHCOK_00330 7.7e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
EJEMHCOK_00331 7.4e-180 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EJEMHCOK_00332 6.5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EJEMHCOK_00333 1e-16 K MerR family regulatory protein
EJEMHCOK_00334 3.1e-195 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
EJEMHCOK_00335 1.7e-143
EJEMHCOK_00336 1.3e-16 K Psort location Cytoplasmic, score
EJEMHCOK_00337 9.1e-16 KLT Protein tyrosine kinase
EJEMHCOK_00338 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EJEMHCOK_00339 1.9e-19 vbsD V MatE
EJEMHCOK_00340 7.8e-200 vbsD V MatE
EJEMHCOK_00341 1.6e-131 S Enoyl-(Acyl carrier protein) reductase
EJEMHCOK_00342 2.3e-133 magIII L endonuclease III
EJEMHCOK_00343 3.8e-93 laaE K Transcriptional regulator PadR-like family
EJEMHCOK_00344 1.8e-176 S Membrane transport protein
EJEMHCOK_00345 3.6e-66 4.1.1.44 S Cupin domain
EJEMHCOK_00346 7.7e-224 hipA 2.7.11.1 S HipA N-terminal domain
EJEMHCOK_00347 3.7e-41 K Helix-turn-helix
EJEMHCOK_00348 4e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
EJEMHCOK_00349 5.4e-19
EJEMHCOK_00350 1.9e-101 K Bacterial regulatory proteins, tetR family
EJEMHCOK_00352 4e-65 T Domain of unknown function (DUF4234)
EJEMHCOK_00353 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
EJEMHCOK_00354 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EJEMHCOK_00355 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EJEMHCOK_00356 4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
EJEMHCOK_00357 1.3e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
EJEMHCOK_00359 5.1e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
EJEMHCOK_00360 0.0 pafB K WYL domain
EJEMHCOK_00361 7e-53
EJEMHCOK_00362 0.0 helY L DEAD DEAH box helicase
EJEMHCOK_00363 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
EJEMHCOK_00364 7.3e-143 pgp 3.1.3.18 S HAD-hyrolase-like
EJEMHCOK_00367 1.6e-90 K Putative zinc ribbon domain
EJEMHCOK_00368 4.2e-126 S GyrI-like small molecule binding domain
EJEMHCOK_00369 2e-92 L DNA integration
EJEMHCOK_00371 7.3e-62
EJEMHCOK_00372 8e-120 K helix_turn_helix, mercury resistance
EJEMHCOK_00373 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
EJEMHCOK_00374 1.2e-141 S Bacterial protein of unknown function (DUF881)
EJEMHCOK_00375 2.6e-31 sbp S Protein of unknown function (DUF1290)
EJEMHCOK_00376 4e-173 S Bacterial protein of unknown function (DUF881)
EJEMHCOK_00377 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EJEMHCOK_00378 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
EJEMHCOK_00379 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
EJEMHCOK_00380 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
EJEMHCOK_00381 2.3e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EJEMHCOK_00382 9.9e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EJEMHCOK_00383 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EJEMHCOK_00384 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
EJEMHCOK_00385 2.8e-145 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EJEMHCOK_00386 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EJEMHCOK_00387 5.7e-30
EJEMHCOK_00388 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EJEMHCOK_00389 5e-246
EJEMHCOK_00390 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EJEMHCOK_00391 1.9e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EJEMHCOK_00392 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EJEMHCOK_00393 1.9e-42 yajC U Preprotein translocase subunit
EJEMHCOK_00394 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EJEMHCOK_00395 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EJEMHCOK_00396 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EJEMHCOK_00397 1e-131 yebC K transcriptional regulatory protein
EJEMHCOK_00398 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
EJEMHCOK_00399 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJEMHCOK_00400 1.7e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EJEMHCOK_00403 1.2e-256
EJEMHCOK_00407 3.7e-156 S PAC2 family
EJEMHCOK_00408 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EJEMHCOK_00409 7.1e-160 G Fructosamine kinase
EJEMHCOK_00410 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EJEMHCOK_00411 5.9e-217 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EJEMHCOK_00412 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
EJEMHCOK_00413 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EJEMHCOK_00414 1.2e-143 yoaK S Protein of unknown function (DUF1275)
EJEMHCOK_00415 7.5e-253 brnQ U Component of the transport system for branched-chain amino acids
EJEMHCOK_00418 5.2e-243 mepA_6 V MatE
EJEMHCOK_00419 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
EJEMHCOK_00420 2.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EJEMHCOK_00421 8e-33 secG U Preprotein translocase SecG subunit
EJEMHCOK_00422 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EJEMHCOK_00423 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
EJEMHCOK_00424 3.1e-173 whiA K May be required for sporulation
EJEMHCOK_00425 1.5e-177 rapZ S Displays ATPase and GTPase activities
EJEMHCOK_00426 1e-181 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
EJEMHCOK_00427 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EJEMHCOK_00428 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EJEMHCOK_00429 6.1e-77
EJEMHCOK_00430 3.1e-58 V MacB-like periplasmic core domain
EJEMHCOK_00432 3.3e-118 K Transcriptional regulatory protein, C terminal
EJEMHCOK_00433 1.4e-238 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EJEMHCOK_00434 1.7e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EJEMHCOK_00435 2.6e-302 ybiT S ABC transporter
EJEMHCOK_00436 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EJEMHCOK_00437 3.3e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EJEMHCOK_00438 4.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
EJEMHCOK_00439 7.1e-217 GK ROK family
EJEMHCOK_00440 6.9e-178 2.7.1.2 GK ROK family
EJEMHCOK_00441 4.6e-182 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
EJEMHCOK_00442 8e-101 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
EJEMHCOK_00443 1.7e-168 G ABC transporter permease
EJEMHCOK_00444 1.1e-173 G Binding-protein-dependent transport system inner membrane component
EJEMHCOK_00445 1.9e-247 G Bacterial extracellular solute-binding protein
EJEMHCOK_00446 1.3e-309 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EJEMHCOK_00447 1.2e-73 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EJEMHCOK_00448 6.7e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EJEMHCOK_00449 5.9e-227 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EJEMHCOK_00450 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
EJEMHCOK_00451 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EJEMHCOK_00452 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EJEMHCOK_00453 1e-127 3.2.1.8 S alpha beta
EJEMHCOK_00454 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EJEMHCOK_00455 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
EJEMHCOK_00456 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EJEMHCOK_00457 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
EJEMHCOK_00458 3.4e-91
EJEMHCOK_00459 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
EJEMHCOK_00460 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
EJEMHCOK_00461 1.2e-275 G ABC transporter substrate-binding protein
EJEMHCOK_00462 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
EJEMHCOK_00463 2.2e-132 M Peptidase family M23
EJEMHCOK_00465 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EJEMHCOK_00466 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
EJEMHCOK_00467 3.3e-158 yeaZ 2.3.1.234 O Glycoprotease family
EJEMHCOK_00468 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
EJEMHCOK_00469 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
EJEMHCOK_00470 0.0 comE S Competence protein
EJEMHCOK_00471 7.7e-93 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
EJEMHCOK_00472 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EJEMHCOK_00473 3.7e-168 ET Bacterial periplasmic substrate-binding proteins
EJEMHCOK_00474 3.7e-171 corA P CorA-like Mg2+ transporter protein
EJEMHCOK_00475 4e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EJEMHCOK_00476 5.3e-300 E Serine carboxypeptidase
EJEMHCOK_00477 0.0 S Psort location Cytoplasmic, score 8.87
EJEMHCOK_00478 1.7e-108 S Domain of unknown function (DUF4194)
EJEMHCOK_00479 8.8e-284 S Psort location Cytoplasmic, score 8.87
EJEMHCOK_00480 6.9e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EJEMHCOK_00481 7.6e-64 yeaO K Protein of unknown function, DUF488
EJEMHCOK_00482 1.5e-120 ydaF_1 J Acetyltransferase (GNAT) domain
EJEMHCOK_00483 7.5e-91 MA20_25245 K FR47-like protein
EJEMHCOK_00484 9.5e-56 K Transcriptional regulator
EJEMHCOK_00485 2.1e-33 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
EJEMHCOK_00487 1.2e-185 S Acetyltransferase (GNAT) domain
EJEMHCOK_00488 7.4e-22 qseC 2.7.13.3 T Histidine kinase
EJEMHCOK_00489 1e-130 S SOS response associated peptidase (SRAP)
EJEMHCOK_00490 1.3e-99
EJEMHCOK_00491 4.7e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EJEMHCOK_00492 1.9e-162 rpoC M heme binding
EJEMHCOK_00493 3e-28 EGP Major facilitator Superfamily
EJEMHCOK_00494 9.8e-100 EGP Major facilitator Superfamily
EJEMHCOK_00496 1.2e-150 3.6.4.12
EJEMHCOK_00497 1.2e-10 CE Amino acid permease
EJEMHCOK_00498 8.6e-96 ypjC S Putative ABC-transporter type IV
EJEMHCOK_00499 1.8e-83 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
EJEMHCOK_00500 6.3e-193 V VanZ like family
EJEMHCOK_00501 4.1e-53 KT RESPONSE REGULATOR receiver
EJEMHCOK_00502 2.7e-70 pdxH S Pfam:Pyridox_oxidase
EJEMHCOK_00503 2.2e-141 yijF S Domain of unknown function (DUF1287)
EJEMHCOK_00504 3.2e-132 C Putative TM nitroreductase
EJEMHCOK_00505 8.9e-109
EJEMHCOK_00507 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
EJEMHCOK_00508 1.3e-78 S Bacterial PH domain
EJEMHCOK_00509 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EJEMHCOK_00510 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EJEMHCOK_00511 1.6e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EJEMHCOK_00513 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJEMHCOK_00514 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EJEMHCOK_00515 4e-93
EJEMHCOK_00516 1.2e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EJEMHCOK_00517 1.7e-284 thrC 4.2.3.1 E Threonine synthase N terminus
EJEMHCOK_00518 6.9e-122 S ABC-2 family transporter protein
EJEMHCOK_00519 8.2e-126 S ABC-2 family transporter protein
EJEMHCOK_00520 1.9e-175 V ATPases associated with a variety of cellular activities
EJEMHCOK_00521 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
EJEMHCOK_00522 8.9e-124 S Haloacid dehalogenase-like hydrolase
EJEMHCOK_00523 1.4e-293 recN L May be involved in recombinational repair of damaged DNA
EJEMHCOK_00524 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EJEMHCOK_00525 1e-234 trkB P Cation transport protein
EJEMHCOK_00526 6.8e-116 trkA P TrkA-N domain
EJEMHCOK_00527 1.4e-100
EJEMHCOK_00528 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EJEMHCOK_00530 1.6e-188 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EJEMHCOK_00531 1.4e-158 L Tetratricopeptide repeat
EJEMHCOK_00532 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EJEMHCOK_00533 1.6e-143 S Putative ABC-transporter type IV
EJEMHCOK_00534 4.7e-108 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EJEMHCOK_00535 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
EJEMHCOK_00536 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
EJEMHCOK_00537 2e-275 3.6.4.12 K Putative DNA-binding domain
EJEMHCOK_00538 2.9e-160 3.1.21.3 V type I restriction modification DNA specificity domain
EJEMHCOK_00539 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
EJEMHCOK_00540 1.7e-156 S Domain of unknown function (DUF4357)
EJEMHCOK_00541 2.4e-30
EJEMHCOK_00542 8.8e-259 S Domain of unknown function (DUF4143)
EJEMHCOK_00543 2e-17 yccF S Inner membrane component domain
EJEMHCOK_00544 3.5e-12
EJEMHCOK_00545 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
EJEMHCOK_00546 3.6e-41 tnp7109-21 L Integrase core domain
EJEMHCOK_00547 2.6e-43 L IstB-like ATP binding protein
EJEMHCOK_00548 1.4e-43 L Transposase
EJEMHCOK_00549 1.3e-38 V ATPases associated with a variety of cellular activities
EJEMHCOK_00550 2e-73 I Sterol carrier protein
EJEMHCOK_00551 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EJEMHCOK_00553 3.4e-35
EJEMHCOK_00554 1.9e-144 gluP 3.4.21.105 S Rhomboid family
EJEMHCOK_00555 1.4e-96 L HTH-like domain
EJEMHCOK_00556 8e-257 L ribosomal rna small subunit methyltransferase
EJEMHCOK_00557 2.6e-71 crgA D Involved in cell division
EJEMHCOK_00558 2.7e-143 S Bacterial protein of unknown function (DUF881)
EJEMHCOK_00559 2.6e-233 srtA 3.4.22.70 M Sortase family
EJEMHCOK_00560 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
EJEMHCOK_00561 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
EJEMHCOK_00562 2e-183 T Protein tyrosine kinase
EJEMHCOK_00563 2.8e-263 pbpA M penicillin-binding protein
EJEMHCOK_00564 8.1e-266 rodA D Belongs to the SEDS family
EJEMHCOK_00565 3.7e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
EJEMHCOK_00566 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
EJEMHCOK_00567 6.8e-130 fhaA T Protein of unknown function (DUF2662)
EJEMHCOK_00568 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
EJEMHCOK_00569 0.0 pip S YhgE Pip domain protein
EJEMHCOK_00570 0.0 pip S YhgE Pip domain protein
EJEMHCOK_00571 5.6e-205 pldB 3.1.1.5 I Serine aminopeptidase, S33
EJEMHCOK_00572 7.4e-167 yicL EG EamA-like transporter family
EJEMHCOK_00573 9e-104
EJEMHCOK_00575 2.1e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJEMHCOK_00577 0.0 KL Domain of unknown function (DUF3427)
EJEMHCOK_00578 2.5e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
EJEMHCOK_00579 1.2e-40 D DivIVA domain protein
EJEMHCOK_00580 9.3e-53 ybjQ S Putative heavy-metal-binding
EJEMHCOK_00581 3.1e-158 I Serine aminopeptidase, S33
EJEMHCOK_00582 2.2e-87 yjcF Q Acetyltransferase (GNAT) domain
EJEMHCOK_00584 6.5e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
EJEMHCOK_00585 0.0 cadA P E1-E2 ATPase
EJEMHCOK_00586 5e-273 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
EJEMHCOK_00587 3.1e-170 htpX O Belongs to the peptidase M48B family
EJEMHCOK_00589 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
EJEMHCOK_00590 1.9e-42 S Bacterial mobilisation protein (MobC)
EJEMHCOK_00591 2.3e-127 S Domain of unknown function (DUF4417)
EJEMHCOK_00593 1.9e-61
EJEMHCOK_00594 3.4e-64
EJEMHCOK_00595 3.9e-50 E IrrE N-terminal-like domain
EJEMHCOK_00596 2e-12 E IrrE N-terminal-like domain
EJEMHCOK_00597 4.9e-57 K Cro/C1-type HTH DNA-binding domain
EJEMHCOK_00598 8.7e-248 3.5.1.104 G Polysaccharide deacetylase
EJEMHCOK_00599 3.3e-200 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
EJEMHCOK_00600 2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EJEMHCOK_00601 1.1e-162 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EJEMHCOK_00602 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EJEMHCOK_00603 8.4e-193 K helix_turn _helix lactose operon repressor
EJEMHCOK_00604 4.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
EJEMHCOK_00605 1.6e-297 scrT G Transporter major facilitator family protein
EJEMHCOK_00606 5e-254 yhjE EGP Sugar (and other) transporter
EJEMHCOK_00607 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EJEMHCOK_00608 8.2e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EJEMHCOK_00609 8.8e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
EJEMHCOK_00611 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EJEMHCOK_00612 5.1e-276 aroP E aromatic amino acid transport protein AroP K03293
EJEMHCOK_00613 7e-101 K Transcriptional regulator C-terminal region
EJEMHCOK_00614 2.6e-129 V ABC transporter
EJEMHCOK_00615 0.0 V FtsX-like permease family
EJEMHCOK_00616 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EJEMHCOK_00617 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EJEMHCOK_00618 2.6e-39 E ABC transporter
EJEMHCOK_00619 2.9e-99 bcp 1.11.1.15 O Redoxin
EJEMHCOK_00620 3.7e-148 S Virulence factor BrkB
EJEMHCOK_00621 1.2e-105 L Transposase
EJEMHCOK_00622 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EJEMHCOK_00623 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EJEMHCOK_00624 5.5e-55 L HNH endonuclease
EJEMHCOK_00625 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
EJEMHCOK_00626 1.2e-132
EJEMHCOK_00627 1.5e-265 EGP Major Facilitator Superfamily
EJEMHCOK_00628 3.5e-41 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
EJEMHCOK_00629 1.5e-121 L Integrase core domain
EJEMHCOK_00630 3.6e-37 L Psort location Cytoplasmic, score 8.87
EJEMHCOK_00631 5e-116 K WHG domain
EJEMHCOK_00632 1.4e-90 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
EJEMHCOK_00634 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
EJEMHCOK_00635 1.5e-97 M Belongs to the glycosyl hydrolase 30 family
EJEMHCOK_00637 3.3e-191 1.1.1.65 C Aldo/keto reductase family
EJEMHCOK_00638 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
EJEMHCOK_00639 0.0 lmrA1 V ABC transporter, ATP-binding protein
EJEMHCOK_00640 0.0 lmrA2 V ABC transporter transmembrane region
EJEMHCOK_00641 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
EJEMHCOK_00642 1.3e-107 S Phosphatidylethanolamine-binding protein
EJEMHCOK_00643 0.0 pepD E Peptidase family C69
EJEMHCOK_00644 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
EJEMHCOK_00645 1.3e-62 S Macrophage migration inhibitory factor (MIF)
EJEMHCOK_00646 1.5e-97 S GtrA-like protein
EJEMHCOK_00647 1.8e-262 EGP Major facilitator Superfamily
EJEMHCOK_00648 1.2e-125 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
EJEMHCOK_00649 1.3e-141
EJEMHCOK_00650 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
EJEMHCOK_00651 8.6e-201 P NMT1/THI5 like
EJEMHCOK_00652 1.2e-123 S HAD hydrolase, family IA, variant 3
EJEMHCOK_00654 9.8e-277 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJEMHCOK_00655 2e-50 S Domain of unknown function (DUF4143)
EJEMHCOK_00656 5.7e-43 S Domain of unknown function (DUF4143)
EJEMHCOK_00659 5.8e-252 S Calcineurin-like phosphoesterase
EJEMHCOK_00660 8.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
EJEMHCOK_00661 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EJEMHCOK_00662 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EJEMHCOK_00663 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
EJEMHCOK_00665 5.3e-177 S CAAX protease self-immunity
EJEMHCOK_00666 1.4e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
EJEMHCOK_00667 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EJEMHCOK_00668 1.1e-224 G Transmembrane secretion effector
EJEMHCOK_00669 7.3e-132 K Bacterial regulatory proteins, tetR family
EJEMHCOK_00670 4.1e-127
EJEMHCOK_00671 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EJEMHCOK_00672 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EJEMHCOK_00673 1.3e-166 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
EJEMHCOK_00674 5.1e-185
EJEMHCOK_00675 7.9e-180
EJEMHCOK_00676 1.1e-162 trxA2 O Tetratricopeptide repeat
EJEMHCOK_00677 1.4e-118 cyaA 4.6.1.1 S CYTH
EJEMHCOK_00680 6.3e-185 K Bacterial regulatory proteins, lacI family
EJEMHCOK_00681 5.3e-18 4.2.1.68 M carboxylic acid catabolic process
EJEMHCOK_00682 2.2e-66 4.2.1.68 M Enolase C-terminal domain-like
EJEMHCOK_00683 6.8e-164 IQ KR domain
EJEMHCOK_00685 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
EJEMHCOK_00686 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
EJEMHCOK_00687 2.3e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
EJEMHCOK_00688 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EJEMHCOK_00689 1.4e-303 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EJEMHCOK_00690 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EJEMHCOK_00691 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
EJEMHCOK_00692 2e-239 hom 1.1.1.3 E Homoserine dehydrogenase
EJEMHCOK_00693 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EJEMHCOK_00694 1.8e-278 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
EJEMHCOK_00695 1.6e-64
EJEMHCOK_00696 6.1e-58
EJEMHCOK_00697 1.6e-163 V ATPases associated with a variety of cellular activities
EJEMHCOK_00698 8.2e-152 V Efflux ABC transporter, permease protein
EJEMHCOK_00699 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
EJEMHCOK_00700 1.7e-237 dapE 3.5.1.18 E Peptidase dimerisation domain
EJEMHCOK_00701 0.0 rne 3.1.26.12 J Ribonuclease E/G family
EJEMHCOK_00702 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
EJEMHCOK_00703 3.1e-40 rpmA J Ribosomal L27 protein
EJEMHCOK_00704 9.1e-214 K Psort location Cytoplasmic, score
EJEMHCOK_00705 1.1e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJEMHCOK_00706 6.9e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EJEMHCOK_00707 5.8e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
EJEMHCOK_00709 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EJEMHCOK_00710 3.6e-109 nusG K Participates in transcription elongation, termination and antitermination
EJEMHCOK_00711 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
EJEMHCOK_00712 2.1e-177 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
EJEMHCOK_00713 9.8e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EJEMHCOK_00714 1.3e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
EJEMHCOK_00715 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
EJEMHCOK_00716 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJEMHCOK_00717 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EJEMHCOK_00718 7.3e-119
EJEMHCOK_00719 7.9e-169 T Pfam Adenylate and Guanylate cyclase catalytic domain
EJEMHCOK_00720 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
EJEMHCOK_00721 1.1e-79 ssb1 L Single-stranded DNA-binding protein
EJEMHCOK_00722 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EJEMHCOK_00723 6.6e-70 rplI J Binds to the 23S rRNA
EJEMHCOK_00725 1.9e-14 S Parallel beta-helix repeats
EJEMHCOK_00726 6.5e-46 S Parallel beta-helix repeats
EJEMHCOK_00727 1e-69 E Domain of unknown function (DUF5011)
EJEMHCOK_00729 1.1e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EJEMHCOK_00730 3.9e-129 M Protein of unknown function (DUF3152)
EJEMHCOK_00731 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
EJEMHCOK_00732 5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EJEMHCOK_00733 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
EJEMHCOK_00734 0.0 inlJ M domain protein
EJEMHCOK_00735 1e-282 M LPXTG cell wall anchor motif
EJEMHCOK_00736 1.4e-212 3.4.22.70 M Sortase family
EJEMHCOK_00737 1.6e-81 S Domain of unknown function (DUF4854)
EJEMHCOK_00738 1.1e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
EJEMHCOK_00739 8e-19 2.1.1.72 S Protein conserved in bacteria
EJEMHCOK_00740 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EJEMHCOK_00741 1.6e-132 M Mechanosensitive ion channel
EJEMHCOK_00742 1.7e-119 K Bacterial regulatory proteins, tetR family
EJEMHCOK_00743 2.2e-240 MA20_36090 S Psort location Cytoplasmic, score 8.87
EJEMHCOK_00744 4.2e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
EJEMHCOK_00745 1.3e-62
EJEMHCOK_00746 4.2e-31 M Belongs to the glycosyl hydrolase 28 family
EJEMHCOK_00748 4.5e-45 K Transcriptional regulator
EJEMHCOK_00749 0.0 fadD 6.2.1.3 I AMP-binding enzyme
EJEMHCOK_00750 3.5e-07 S Scramblase
EJEMHCOK_00751 8.8e-32
EJEMHCOK_00756 1.3e-12 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
EJEMHCOK_00757 3e-237 K Helix-turn-helix XRE-family like proteins
EJEMHCOK_00758 3.7e-54 relB L RelB antitoxin
EJEMHCOK_00759 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
EJEMHCOK_00760 2e-132 K helix_turn_helix, mercury resistance
EJEMHCOK_00761 4.3e-242 yxiO S Vacuole effluxer Atg22 like
EJEMHCOK_00763 6.5e-201 yegV G pfkB family carbohydrate kinase
EJEMHCOK_00764 1.4e-29 rpmB J Ribosomal L28 family
EJEMHCOK_00765 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
EJEMHCOK_00766 1.2e-220 steT E amino acid
EJEMHCOK_00769 0.0
EJEMHCOK_00770 9.9e-249 U Sodium:dicarboxylate symporter family
EJEMHCOK_00771 3.8e-114 rsmD 2.1.1.171 L Conserved hypothetical protein 95
EJEMHCOK_00772 2.9e-105 XK27_02070 S Nitroreductase family
EJEMHCOK_00773 3.8e-81 hsp20 O Hsp20/alpha crystallin family
EJEMHCOK_00774 4.3e-162 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EJEMHCOK_00775 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EJEMHCOK_00776 1.8e-34 CP_0960 S Belongs to the UPF0109 family
EJEMHCOK_00777 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EJEMHCOK_00778 8.5e-295 ydfD EK Alanine-glyoxylate amino-transferase
EJEMHCOK_00779 5.9e-94 argO S LysE type translocator
EJEMHCOK_00780 2e-219 S Endonuclease/Exonuclease/phosphatase family
EJEMHCOK_00781 1.6e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EJEMHCOK_00782 1.4e-164 P Cation efflux family
EJEMHCOK_00783 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
EJEMHCOK_00784 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
EJEMHCOK_00785 0.0 yjjK S ABC transporter
EJEMHCOK_00786 2e-58 S Protein of unknown function (DUF3039)
EJEMHCOK_00787 1.7e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EJEMHCOK_00788 3.6e-107
EJEMHCOK_00789 2.3e-113 yceD S Uncharacterized ACR, COG1399
EJEMHCOK_00790 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EJEMHCOK_00791 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EJEMHCOK_00792 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
EJEMHCOK_00793 7.6e-92 ilvN 2.2.1.6 E ACT domain
EJEMHCOK_00795 4.4e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EJEMHCOK_00796 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EJEMHCOK_00797 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EJEMHCOK_00798 3.8e-174 S Auxin Efflux Carrier
EJEMHCOK_00801 0.0 pgi 5.3.1.9 G Belongs to the GPI family
EJEMHCOK_00802 4.7e-109 3.4.22.70 M Sortase family
EJEMHCOK_00803 3.8e-192 ykiI
EJEMHCOK_00804 4.4e-31 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
EJEMHCOK_00805 2e-23 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
EJEMHCOK_00806 1.5e-272 abcT3 P ATPases associated with a variety of cellular activities
EJEMHCOK_00807 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
EJEMHCOK_00808 1.4e-134 K Putative sugar-binding domain
EJEMHCOK_00809 2.6e-212 gatC G PTS system sugar-specific permease component
EJEMHCOK_00810 1.5e-294 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
EJEMHCOK_00811 3.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
EJEMHCOK_00812 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
EJEMHCOK_00813 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EJEMHCOK_00814 7.6e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EJEMHCOK_00815 1.2e-131 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EJEMHCOK_00816 2.2e-207 K helix_turn _helix lactose operon repressor
EJEMHCOK_00817 2.2e-10 fadD 6.2.1.3 I AMP-binding enzyme
EJEMHCOK_00818 0.0 fadD 6.2.1.3 I AMP-binding enzyme
EJEMHCOK_00819 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EJEMHCOK_00820 1.3e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EJEMHCOK_00823 9.7e-299 G Glycosyl hydrolases family 43
EJEMHCOK_00824 1.9e-203 K helix_turn _helix lactose operon repressor
EJEMHCOK_00825 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
EJEMHCOK_00826 2.9e-122 L Protein of unknown function (DUF1524)
EJEMHCOK_00827 4.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
EJEMHCOK_00828 1.8e-306 EGP Major facilitator Superfamily
EJEMHCOK_00829 3.6e-227
EJEMHCOK_00830 3.9e-179 S G5
EJEMHCOK_00831 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
EJEMHCOK_00832 4.8e-119 F Domain of unknown function (DUF4916)
EJEMHCOK_00833 1.3e-159 mhpC I Alpha/beta hydrolase family
EJEMHCOK_00834 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
EJEMHCOK_00835 0.0 enhA_2 S L,D-transpeptidase catalytic domain
EJEMHCOK_00836 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
EJEMHCOK_00837 5.3e-240 S Uncharacterized conserved protein (DUF2183)
EJEMHCOK_00838 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
EJEMHCOK_00839 1.6e-170 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EJEMHCOK_00840 2.2e-119 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
EJEMHCOK_00841 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
EJEMHCOK_00842 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
EJEMHCOK_00843 1.9e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
EJEMHCOK_00844 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
EJEMHCOK_00845 3.1e-139 glpR K DeoR C terminal sensor domain
EJEMHCOK_00846 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
EJEMHCOK_00847 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
EJEMHCOK_00848 4.3e-242 EGP Sugar (and other) transporter
EJEMHCOK_00849 4.2e-43 gcvR T Belongs to the UPF0237 family
EJEMHCOK_00850 7.2e-253 S UPF0210 protein
EJEMHCOK_00851 8.7e-16
EJEMHCOK_00852 2.5e-72
EJEMHCOK_00854 3.1e-121 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EJEMHCOK_00855 2.5e-67 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
EJEMHCOK_00856 2.1e-29 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G xyloglucan:xyloglucosyl transferase activity
EJEMHCOK_00857 3e-184 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
EJEMHCOK_00858 1.4e-105
EJEMHCOK_00859 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJEMHCOK_00860 4.9e-295 L PFAM Integrase catalytic
EJEMHCOK_00861 4.1e-144 L IstB-like ATP binding protein
EJEMHCOK_00862 5.9e-146 QT PucR C-terminal helix-turn-helix domain
EJEMHCOK_00863 0.0
EJEMHCOK_00864 4e-153 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
EJEMHCOK_00865 4.2e-93 bioY S BioY family
EJEMHCOK_00866 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
EJEMHCOK_00867 7.2e-308 pccB I Carboxyl transferase domain
EJEMHCOK_00868 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
EJEMHCOK_00869 1.1e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EJEMHCOK_00870 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
EJEMHCOK_00872 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
EJEMHCOK_00873 1.3e-117
EJEMHCOK_00874 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EJEMHCOK_00875 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EJEMHCOK_00876 7.2e-116 xylR K purine nucleotide biosynthetic process
EJEMHCOK_00877 1e-91 lemA S LemA family
EJEMHCOK_00878 0.0 S Predicted membrane protein (DUF2207)
EJEMHCOK_00879 9.2e-74 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EJEMHCOK_00880 1.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJEMHCOK_00882 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJEMHCOK_00883 1.5e-98 nrdI F Probably involved in ribonucleotide reductase function
EJEMHCOK_00884 2.2e-41 nrdH O Glutaredoxin
EJEMHCOK_00885 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
EJEMHCOK_00886 6.3e-119 L Transposase and inactivated derivatives IS30 family
EJEMHCOK_00887 0.0 yegQ O Peptidase family U32 C-terminal domain
EJEMHCOK_00888 9.3e-189 yfiH Q Multi-copper polyphenol oxidoreductase laccase
EJEMHCOK_00889 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EJEMHCOK_00890 3e-127 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EJEMHCOK_00891 3.5e-51 D nuclear chromosome segregation
EJEMHCOK_00892 3.2e-269 pepC 3.4.22.40 E Peptidase C1-like family
EJEMHCOK_00893 4.3e-165 L Excalibur calcium-binding domain
EJEMHCOK_00894 1.4e-217 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EJEMHCOK_00895 7.3e-245 EGP Major facilitator Superfamily
EJEMHCOK_00896 1e-105 K helix_turn_helix, Arsenical Resistance Operon Repressor
EJEMHCOK_00897 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EJEMHCOK_00898 1.9e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EJEMHCOK_00899 4.2e-245 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
EJEMHCOK_00900 3.7e-128 KT Transcriptional regulatory protein, C terminal
EJEMHCOK_00901 2.3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
EJEMHCOK_00902 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
EJEMHCOK_00903 6.2e-180 pstA P Phosphate transport system permease
EJEMHCOK_00904 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EJEMHCOK_00905 1.9e-169 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
EJEMHCOK_00906 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
EJEMHCOK_00907 8.8e-222 pbuO S Permease family
EJEMHCOK_00909 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
EJEMHCOK_00910 4.1e-184 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
EJEMHCOK_00911 8.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EJEMHCOK_00912 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EJEMHCOK_00914 2.2e-248 T Forkhead associated domain
EJEMHCOK_00915 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
EJEMHCOK_00916 2.8e-41
EJEMHCOK_00917 3.2e-38 fmdB S Putative regulatory protein
EJEMHCOK_00918 1.8e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
EJEMHCOK_00919 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
EJEMHCOK_00920 6.3e-148
EJEMHCOK_00921 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EJEMHCOK_00922 2.1e-132 bla1 3.5.2.6 V Beta-lactamase enzyme family
EJEMHCOK_00923 8.5e-42 KLT Associated with various cellular activities
EJEMHCOK_00927 1.9e-25 rpmG J Ribosomal protein L33
EJEMHCOK_00928 1.5e-214 murB 1.3.1.98 M Cell wall formation
EJEMHCOK_00929 9e-61 fdxA C 4Fe-4S binding domain
EJEMHCOK_00930 1.9e-225 dapC E Aminotransferase class I and II
EJEMHCOK_00931 2.3e-240 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EJEMHCOK_00933 1.1e-256 M Bacterial capsule synthesis protein PGA_cap
EJEMHCOK_00934 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
EJEMHCOK_00935 7.4e-119
EJEMHCOK_00936 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
EJEMHCOK_00937 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EJEMHCOK_00938 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
EJEMHCOK_00939 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EJEMHCOK_00940 2.8e-232 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
EJEMHCOK_00941 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EJEMHCOK_00942 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
EJEMHCOK_00943 2.6e-133 ywiC S YwiC-like protein
EJEMHCOK_00944 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
EJEMHCOK_00945 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EJEMHCOK_00946 1.9e-118 rplD J Forms part of the polypeptide exit tunnel
EJEMHCOK_00947 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EJEMHCOK_00948 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EJEMHCOK_00949 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EJEMHCOK_00950 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EJEMHCOK_00951 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EJEMHCOK_00952 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EJEMHCOK_00953 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
EJEMHCOK_00954 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EJEMHCOK_00955 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EJEMHCOK_00956 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EJEMHCOK_00957 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJEMHCOK_00958 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJEMHCOK_00959 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EJEMHCOK_00960 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EJEMHCOK_00961 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EJEMHCOK_00962 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EJEMHCOK_00963 1e-24 rpmD J Ribosomal protein L30p/L7e
EJEMHCOK_00964 2.7e-63 rplO J binds to the 23S rRNA
EJEMHCOK_00965 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EJEMHCOK_00966 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EJEMHCOK_00967 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EJEMHCOK_00968 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EJEMHCOK_00969 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EJEMHCOK_00970 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EJEMHCOK_00971 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJEMHCOK_00972 8.1e-64 rplQ J Ribosomal protein L17
EJEMHCOK_00973 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
EJEMHCOK_00974 3.2e-172 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EJEMHCOK_00975 0.0 gcs2 S A circularly permuted ATPgrasp
EJEMHCOK_00976 1.3e-153 E Transglutaminase/protease-like homologues
EJEMHCOK_00978 3.9e-39 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
EJEMHCOK_00979 1.6e-161
EJEMHCOK_00980 2.8e-188 nusA K Participates in both transcription termination and antitermination
EJEMHCOK_00981 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EJEMHCOK_00982 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EJEMHCOK_00983 4.5e-236 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EJEMHCOK_00984 6.9e-234 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
EJEMHCOK_00985 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EJEMHCOK_00986 1.2e-106
EJEMHCOK_00988 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EJEMHCOK_00989 5.2e-198 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EJEMHCOK_00990 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
EJEMHCOK_00991 2.9e-260 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJEMHCOK_00992 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
EJEMHCOK_00994 1e-42 M Spy0128-like isopeptide containing domain
EJEMHCOK_00995 4.2e-45 M Spy0128-like isopeptide containing domain
EJEMHCOK_00996 0.0 crr G pts system, glucose-specific IIABC component
EJEMHCOK_00997 7.6e-152 arbG K CAT RNA binding domain
EJEMHCOK_00998 1.9e-211 I Diacylglycerol kinase catalytic domain
EJEMHCOK_00999 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
EJEMHCOK_01000 4e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJEMHCOK_01002 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
EJEMHCOK_01004 1e-93
EJEMHCOK_01005 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EJEMHCOK_01006 5.8e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
EJEMHCOK_01007 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
EJEMHCOK_01008 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EJEMHCOK_01009 9.2e-126 degU K helix_turn_helix, Lux Regulon
EJEMHCOK_01010 8.9e-273 tcsS3 KT PspC domain
EJEMHCOK_01011 7.3e-290 pspC KT PspC domain
EJEMHCOK_01012 8.5e-131
EJEMHCOK_01013 1.5e-112 S Protein of unknown function (DUF4125)
EJEMHCOK_01014 0.0 S Domain of unknown function (DUF4037)
EJEMHCOK_01015 1.2e-216 araJ EGP Major facilitator Superfamily
EJEMHCOK_01017 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EJEMHCOK_01018 9.5e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EJEMHCOK_01019 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EJEMHCOK_01020 1e-09 EGP Major facilitator Superfamily
EJEMHCOK_01021 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
EJEMHCOK_01022 2e-217 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EJEMHCOK_01023 2.6e-39
EJEMHCOK_01024 1.7e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EJEMHCOK_01025 3.1e-176 usp 3.5.1.28 CBM50 S CHAP domain
EJEMHCOK_01026 6e-106 M NlpC/P60 family
EJEMHCOK_01027 1.6e-191 T Universal stress protein family
EJEMHCOK_01028 3.2e-71 attW O OsmC-like protein
EJEMHCOK_01029 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EJEMHCOK_01030 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
EJEMHCOK_01031 1.8e-95 ptpA 3.1.3.48 T low molecular weight
EJEMHCOK_01032 3.7e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
EJEMHCOK_01033 9.4e-23 azlD E Branched-chain amino acid transport protein (AzlD)
EJEMHCOK_01034 4.9e-111 vex2 V ABC transporter, ATP-binding protein
EJEMHCOK_01035 3e-210 vex1 V Efflux ABC transporter, permease protein
EJEMHCOK_01036 4.7e-220 vex3 V ABC transporter permease
EJEMHCOK_01038 6.6e-172
EJEMHCOK_01039 1.2e-67 ytrE V ABC transporter
EJEMHCOK_01040 1.2e-101 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EJEMHCOK_01041 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EJEMHCOK_01042 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EJEMHCOK_01043 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EJEMHCOK_01044 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EJEMHCOK_01045 1.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJEMHCOK_01046 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EJEMHCOK_01047 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJEMHCOK_01049 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
EJEMHCOK_01050 2e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EJEMHCOK_01052 4.6e-35
EJEMHCOK_01053 0.0 K RNA polymerase II activating transcription factor binding
EJEMHCOK_01054 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
EJEMHCOK_01055 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EJEMHCOK_01057 3.2e-101 mntP P Probably functions as a manganese efflux pump
EJEMHCOK_01058 1.4e-125
EJEMHCOK_01059 4.8e-134 KT Transcriptional regulatory protein, C terminal
EJEMHCOK_01060 1.9e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EJEMHCOK_01061 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
EJEMHCOK_01062 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EJEMHCOK_01063 0.0 S domain protein
EJEMHCOK_01064 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
EJEMHCOK_01065 2.4e-90 lrp_3 K helix_turn_helix ASNC type
EJEMHCOK_01066 1e-234 E Aminotransferase class I and II
EJEMHCOK_01067 0.0 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EJEMHCOK_01068 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
EJEMHCOK_01069 2.5e-52 S Protein of unknown function (DUF2469)
EJEMHCOK_01070 1.1e-197 2.3.1.57 J Acetyltransferase (GNAT) domain
EJEMHCOK_01071 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJEMHCOK_01072 9.2e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EJEMHCOK_01073 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJEMHCOK_01074 2.5e-81 V ABC transporter
EJEMHCOK_01075 3.3e-40 V ABC transporter
EJEMHCOK_01076 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
EJEMHCOK_01077 5.9e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EJEMHCOK_01078 3.4e-199 rmuC S RmuC family
EJEMHCOK_01079 9.6e-43 csoR S Metal-sensitive transcriptional repressor
EJEMHCOK_01080 0.0 pacS 3.6.3.54 P E1-E2 ATPase
EJEMHCOK_01081 0.0 ubiB S ABC1 family
EJEMHCOK_01082 3.5e-19 S granule-associated protein
EJEMHCOK_01083 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
EJEMHCOK_01084 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
EJEMHCOK_01085 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EJEMHCOK_01086 1.6e-250 dinF V MatE
EJEMHCOK_01087 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
EJEMHCOK_01088 1e-54 glnB K Nitrogen regulatory protein P-II
EJEMHCOK_01089 7.7e-220 amt U Ammonium Transporter Family
EJEMHCOK_01090 5.3e-202 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EJEMHCOK_01092 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
EJEMHCOK_01093 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
EJEMHCOK_01094 0.0 S Glycosyl hydrolases related to GH101 family, GH129
EJEMHCOK_01095 1.4e-305 pepD E Peptidase family C69
EJEMHCOK_01096 2.9e-19 XK26_04485 P Cobalt transport protein
EJEMHCOK_01097 3.7e-67 XK26_04485 P Cobalt transport protein
EJEMHCOK_01098 2e-82
EJEMHCOK_01099 0.0 V ABC transporter transmembrane region
EJEMHCOK_01100 5.4e-301 V ABC transporter, ATP-binding protein
EJEMHCOK_01101 2.7e-82 K Winged helix DNA-binding domain
EJEMHCOK_01102 3e-73 E IrrE N-terminal-like domain
EJEMHCOK_01104 1.7e-159 S Sucrose-6F-phosphate phosphohydrolase
EJEMHCOK_01105 6e-241 S Putative ABC-transporter type IV
EJEMHCOK_01106 7e-81
EJEMHCOK_01107 6.2e-35 Q phosphatase activity
EJEMHCOK_01108 1.4e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
EJEMHCOK_01109 2e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
EJEMHCOK_01110 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
EJEMHCOK_01111 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EJEMHCOK_01112 9.3e-68 S haloacid dehalogenase-like hydrolase
EJEMHCOK_01113 3.6e-131 yydK K UTRA
EJEMHCOK_01114 1.3e-70 S FMN_bind
EJEMHCOK_01115 2.2e-148 macB V ABC transporter, ATP-binding protein
EJEMHCOK_01116 1.3e-203 Z012_06715 V FtsX-like permease family
EJEMHCOK_01117 4.8e-222 macB_2 V ABC transporter permease
EJEMHCOK_01118 9.2e-234 S Predicted membrane protein (DUF2318)
EJEMHCOK_01119 1.8e-106 tpd P Fe2+ transport protein
EJEMHCOK_01120 2.5e-306 efeU_1 P Iron permease FTR1 family
EJEMHCOK_01121 5.9e-22 G MFS/sugar transport protein
EJEMHCOK_01122 7.6e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EJEMHCOK_01123 9.1e-126 S Fic/DOC family
EJEMHCOK_01124 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EJEMHCOK_01125 5e-38 ptsH G PTS HPr component phosphorylation site
EJEMHCOK_01126 4.4e-200 K helix_turn _helix lactose operon repressor
EJEMHCOK_01127 1.4e-212 holB 2.7.7.7 L DNA polymerase III
EJEMHCOK_01128 1.1e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EJEMHCOK_01129 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EJEMHCOK_01130 2.3e-188 3.6.1.27 I PAP2 superfamily
EJEMHCOK_01131 0.0 vpr M PA domain
EJEMHCOK_01132 1.4e-122 yplQ S Haemolysin-III related
EJEMHCOK_01133 2.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
EJEMHCOK_01134 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
EJEMHCOK_01135 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EJEMHCOK_01136 3.3e-277 S Calcineurin-like phosphoesterase
EJEMHCOK_01137 3e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
EJEMHCOK_01138 4.1e-286 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
EJEMHCOK_01139 1.7e-116
EJEMHCOK_01140 2.6e-213 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EJEMHCOK_01142 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
EJEMHCOK_01143 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
EJEMHCOK_01144 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EJEMHCOK_01145 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
EJEMHCOK_01146 8.4e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
EJEMHCOK_01147 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
EJEMHCOK_01148 4.8e-55 U TadE-like protein
EJEMHCOK_01149 1.9e-41 S Protein of unknown function (DUF4244)
EJEMHCOK_01150 2.6e-29 gspF NU Type II secretion system (T2SS), protein F
EJEMHCOK_01151 3.1e-17 gspF NU Type II secretion system (T2SS), protein F
EJEMHCOK_01152 5.1e-122 U Type ii secretion system
EJEMHCOK_01153 9.8e-191 cpaF U Type II IV secretion system protein
EJEMHCOK_01154 5.2e-153 cpaE D bacterial-type flagellum organization
EJEMHCOK_01156 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EJEMHCOK_01157 1.2e-199 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
EJEMHCOK_01158 5.9e-92
EJEMHCOK_01160 5.1e-49 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EJEMHCOK_01161 2e-208 S Glycosyltransferase, group 2 family protein
EJEMHCOK_01162 2e-277
EJEMHCOK_01163 3.3e-26 thiS 2.8.1.10 H ThiS family
EJEMHCOK_01164 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EJEMHCOK_01165 0.0 S Psort location Cytoplasmic, score 8.87
EJEMHCOK_01166 5.3e-28 gtrB GT2 M Glycosyl transferase family 2
EJEMHCOK_01167 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
EJEMHCOK_01168 3.4e-245 V ABC transporter permease
EJEMHCOK_01169 1.1e-181 V ABC transporter
EJEMHCOK_01170 2.1e-137 T HD domain
EJEMHCOK_01171 3e-164 S Glutamine amidotransferase domain
EJEMHCOK_01173 0.0 kup P Transport of potassium into the cell
EJEMHCOK_01174 5.9e-185 tatD L TatD related DNase
EJEMHCOK_01175 2e-253 xylR 5.3.1.12 G MFS/sugar transport protein
EJEMHCOK_01177 2.9e-79 K Transcriptional regulator
EJEMHCOK_01178 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJEMHCOK_01179 1.6e-130
EJEMHCOK_01180 8.6e-59
EJEMHCOK_01181 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EJEMHCOK_01182 5.9e-126 dedA S SNARE associated Golgi protein
EJEMHCOK_01184 4.7e-140 S HAD hydrolase, family IA, variant 3
EJEMHCOK_01185 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
EJEMHCOK_01186 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
EJEMHCOK_01187 6.8e-87 hspR K transcriptional regulator, MerR family
EJEMHCOK_01188 2.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
EJEMHCOK_01189 1.4e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EJEMHCOK_01190 0.0 dnaK O Heat shock 70 kDa protein
EJEMHCOK_01191 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
EJEMHCOK_01192 1.2e-188 K Psort location Cytoplasmic, score
EJEMHCOK_01194 1.8e-138 G Phosphoglycerate mutase family
EJEMHCOK_01195 8e-70 S Protein of unknown function (DUF4235)
EJEMHCOK_01196 5.6e-141 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
EJEMHCOK_01197 4.1e-45
EJEMHCOK_01198 3.3e-103 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJEMHCOK_01200 1.9e-283
EJEMHCOK_01201 5.3e-163 S Protein of unknown function (DUF3801)
EJEMHCOK_01202 2.9e-280 ltrBE1 U Relaxase/Mobilisation nuclease domain
EJEMHCOK_01203 6.9e-52 S Bacterial mobilisation protein (MobC)
EJEMHCOK_01204 2.3e-19 S Protein of unknown function (DUF2442)
EJEMHCOK_01205 1.2e-94
EJEMHCOK_01206 0.0 topB 5.99.1.2 L DNA topoisomerase
EJEMHCOK_01207 8.5e-82
EJEMHCOK_01208 9.4e-60
EJEMHCOK_01209 2.1e-45
EJEMHCOK_01210 1.2e-233 S HipA-like C-terminal domain
EJEMHCOK_01211 2.1e-94
EJEMHCOK_01212 7.4e-24
EJEMHCOK_01213 1.1e-26
EJEMHCOK_01214 1.3e-142 fic D Fic/DOC family
EJEMHCOK_01215 5.8e-247 L Phage integrase family
EJEMHCOK_01216 3.6e-210 L Transposase and inactivated derivatives IS30 family
EJEMHCOK_01217 2.3e-07
EJEMHCOK_01218 1.1e-49 relB L RelB antitoxin
EJEMHCOK_01219 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
EJEMHCOK_01220 1.9e-208 E Belongs to the peptidase S1B family
EJEMHCOK_01221 6.9e-12
EJEMHCOK_01222 2.7e-28
EJEMHCOK_01223 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EJEMHCOK_01224 3.8e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EJEMHCOK_01225 1.4e-47 S Domain of unknown function (DUF4193)
EJEMHCOK_01226 1.7e-172 S Protein of unknown function (DUF3071)
EJEMHCOK_01227 6.5e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
EJEMHCOK_01228 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
EJEMHCOK_01229 0.0 lhr L DEAD DEAH box helicase
EJEMHCOK_01230 1.5e-24 yozG K Cro/C1-type HTH DNA-binding domain
EJEMHCOK_01231 1.3e-43 S Protein of unknown function (DUF2975)
EJEMHCOK_01232 2.3e-278 aspA 4.3.1.1 E Fumarase C C-terminus
EJEMHCOK_01233 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
EJEMHCOK_01234 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EJEMHCOK_01235 1e-122
EJEMHCOK_01236 3e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
EJEMHCOK_01237 0.0 pknL 2.7.11.1 KLT PASTA
EJEMHCOK_01238 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
EJEMHCOK_01239 1.5e-109
EJEMHCOK_01240 1.1e-192 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EJEMHCOK_01241 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EJEMHCOK_01242 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EJEMHCOK_01243 1e-07
EJEMHCOK_01244 2.9e-87 recX S Modulates RecA activity
EJEMHCOK_01245 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EJEMHCOK_01246 3.7e-40 S Protein of unknown function (DUF3046)
EJEMHCOK_01247 1.6e-80 K Helix-turn-helix XRE-family like proteins
EJEMHCOK_01248 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
EJEMHCOK_01249 9.2e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EJEMHCOK_01250 0.0 ftsK D FtsK SpoIIIE family protein
EJEMHCOK_01251 1.2e-137 fic D Fic/DOC family
EJEMHCOK_01252 3.1e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EJEMHCOK_01253 2.8e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJEMHCOK_01254 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
EJEMHCOK_01255 1.1e-167 ydeD EG EamA-like transporter family
EJEMHCOK_01256 6.6e-132 ybhL S Belongs to the BI1 family
EJEMHCOK_01257 1e-97 S Domain of unknown function (DUF5067)
EJEMHCOK_01258 2.9e-268 T Histidine kinase
EJEMHCOK_01259 1.1e-116 K helix_turn_helix, Lux Regulon
EJEMHCOK_01260 0.0 S Protein of unknown function DUF262
EJEMHCOK_01261 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
EJEMHCOK_01262 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
EJEMHCOK_01263 1e-237 carA 6.3.5.5 F Belongs to the CarA family
EJEMHCOK_01264 3.2e-84 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EJEMHCOK_01265 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EJEMHCOK_01267 1e-191 EGP Transmembrane secretion effector
EJEMHCOK_01268 0.0 S Esterase-like activity of phytase
EJEMHCOK_01269 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EJEMHCOK_01270 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EJEMHCOK_01271 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EJEMHCOK_01272 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EJEMHCOK_01274 1.3e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
EJEMHCOK_01275 4.1e-228 M Glycosyl transferase 4-like domain
EJEMHCOK_01276 0.0 M Parallel beta-helix repeats
EJEMHCOK_01277 3.2e-234 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EJEMHCOK_01278 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EJEMHCOK_01279 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
EJEMHCOK_01280 3e-114
EJEMHCOK_01281 5.5e-94 S Protein of unknown function (DUF4230)
EJEMHCOK_01282 2.3e-104 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
EJEMHCOK_01283 6.2e-29 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EJEMHCOK_01284 1.8e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EJEMHCOK_01285 2e-32
EJEMHCOK_01286 5.7e-302 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
EJEMHCOK_01287 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EJEMHCOK_01288 1.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EJEMHCOK_01289 1.4e-239 purD 6.3.4.13 F Belongs to the GARS family
EJEMHCOK_01290 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
EJEMHCOK_01291 2.7e-247 S Putative esterase
EJEMHCOK_01292 0.0 lysX S Uncharacterised conserved protein (DUF2156)
EJEMHCOK_01294 3e-162 P Zinc-uptake complex component A periplasmic
EJEMHCOK_01295 1.8e-139 S cobalamin synthesis protein
EJEMHCOK_01296 6.1e-48 rpmB J Ribosomal L28 family
EJEMHCOK_01297 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJEMHCOK_01298 2e-42 rpmE2 J Ribosomal protein L31
EJEMHCOK_01299 8.2e-15 rpmJ J Ribosomal protein L36
EJEMHCOK_01300 2.3e-23 J Ribosomal L32p protein family
EJEMHCOK_01301 3.6e-202 ycgR S Predicted permease
EJEMHCOK_01302 2.6e-154 S TIGRFAM TIGR03943 family protein
EJEMHCOK_01303 1.5e-45
EJEMHCOK_01304 5.1e-74 zur P Belongs to the Fur family
EJEMHCOK_01305 2.4e-228 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EJEMHCOK_01306 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EJEMHCOK_01307 8.5e-179 adh3 C Zinc-binding dehydrogenase
EJEMHCOK_01308 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EJEMHCOK_01310 1.4e-44 S Memo-like protein
EJEMHCOK_01311 1.1e-225 K Putative ATP-dependent DNA helicase recG C-terminal
EJEMHCOK_01312 6.6e-159 K Helix-turn-helix domain, rpiR family
EJEMHCOK_01313 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EJEMHCOK_01314 1.1e-247 dgt 3.1.5.1 F Phosphohydrolase-associated domain
EJEMHCOK_01315 1e-262 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EJEMHCOK_01316 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
EJEMHCOK_01317 1e-92 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJEMHCOK_01318 1.4e-10 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EJEMHCOK_01319 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EJEMHCOK_01320 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
EJEMHCOK_01321 1.2e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EJEMHCOK_01322 1.2e-191 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
EJEMHCOK_01323 4.4e-109
EJEMHCOK_01324 4.9e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
EJEMHCOK_01325 1.8e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EJEMHCOK_01326 1.3e-112
EJEMHCOK_01327 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
EJEMHCOK_01328 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EJEMHCOK_01329 1.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EJEMHCOK_01330 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
EJEMHCOK_01331 3.9e-07 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
EJEMHCOK_01333 1.2e-76 yneG S Domain of unknown function (DUF4186)
EJEMHCOK_01334 5.8e-174 dkgA 1.1.1.346 C Aldo/keto reductase family
EJEMHCOK_01335 1.3e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
EJEMHCOK_01336 8.9e-203 K WYL domain
EJEMHCOK_01339 0.0 4.2.1.53 S MCRA family
EJEMHCOK_01340 4.5e-46 yhbY J CRS1_YhbY
EJEMHCOK_01341 6.2e-84 S zinc-ribbon domain
EJEMHCOK_01342 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
EJEMHCOK_01343 2.7e-46 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
EJEMHCOK_01344 5.1e-192 ywqG S Domain of unknown function (DUF1963)
EJEMHCOK_01345 5.3e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EJEMHCOK_01346 2.8e-140 recO L Involved in DNA repair and RecF pathway recombination
EJEMHCOK_01347 1.2e-291 I acetylesterase activity
EJEMHCOK_01348 4.7e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EJEMHCOK_01349 1.2e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EJEMHCOK_01350 1.6e-203 2.7.11.1 NU Tfp pilus assembly protein FimV
EJEMHCOK_01352 1.2e-82
EJEMHCOK_01353 9.6e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
EJEMHCOK_01354 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EJEMHCOK_01355 7.4e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
EJEMHCOK_01356 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
EJEMHCOK_01357 3.3e-200 ftsE D Cell division ATP-binding protein FtsE
EJEMHCOK_01358 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EJEMHCOK_01359 1.2e-146 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
EJEMHCOK_01360 6e-63
EJEMHCOK_01362 5.8e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EJEMHCOK_01363 8.9e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EJEMHCOK_01364 2.9e-86 3.1.21.3 V DivIVA protein
EJEMHCOK_01365 2.1e-42 yggT S YGGT family
EJEMHCOK_01366 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EJEMHCOK_01367 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EJEMHCOK_01368 9.5e-247 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EJEMHCOK_01369 8.8e-300 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
EJEMHCOK_01370 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
EJEMHCOK_01371 6.8e-159 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EJEMHCOK_01372 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EJEMHCOK_01373 1.2e-75
EJEMHCOK_01374 6.9e-231 O AAA domain (Cdc48 subfamily)
EJEMHCOK_01375 7e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EJEMHCOK_01376 1.2e-61 S Thiamine-binding protein
EJEMHCOK_01377 2.2e-190 K helix_turn _helix lactose operon repressor
EJEMHCOK_01378 5.7e-47 S Protein of unknown function (DUF3052)
EJEMHCOK_01379 5.5e-150 lon T Belongs to the peptidase S16 family
EJEMHCOK_01380 1.8e-284 S Zincin-like metallopeptidase
EJEMHCOK_01381 1.3e-282 uvrD2 3.6.4.12 L DNA helicase
EJEMHCOK_01382 4.6e-245 mphA S Aminoglycoside phosphotransferase
EJEMHCOK_01383 6.1e-32 S Protein of unknown function (DUF3107)
EJEMHCOK_01384 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
EJEMHCOK_01385 7.6e-115 S Vitamin K epoxide reductase
EJEMHCOK_01386 1.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
EJEMHCOK_01387 1.1e-152 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EJEMHCOK_01388 3.6e-169 S Patatin-like phospholipase
EJEMHCOK_01389 0.0 V ABC transporter transmembrane region
EJEMHCOK_01390 0.0 V ABC transporter, ATP-binding protein
EJEMHCOK_01391 5.8e-89 K MarR family
EJEMHCOK_01392 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
EJEMHCOK_01393 2.5e-255 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
EJEMHCOK_01394 5.1e-162
EJEMHCOK_01395 2.2e-212 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
EJEMHCOK_01396 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
EJEMHCOK_01398 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EJEMHCOK_01399 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
EJEMHCOK_01400 8.5e-273 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EJEMHCOK_01401 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EJEMHCOK_01402 8e-171 S Endonuclease/Exonuclease/phosphatase family
EJEMHCOK_01404 7.6e-58 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EJEMHCOK_01405 4.8e-257 cdr OP Sulfurtransferase TusA
EJEMHCOK_01406 2.6e-149 moeB 2.7.7.80 H ThiF family
EJEMHCOK_01407 5.4e-133 tmp1 S Domain of unknown function (DUF4391)
EJEMHCOK_01408 2e-156 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
EJEMHCOK_01409 2.9e-229 aspB E Aminotransferase class-V
EJEMHCOK_01410 2.5e-101 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
EJEMHCOK_01411 6.1e-271 S zinc finger
EJEMHCOK_01412 4.4e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EJEMHCOK_01413 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJEMHCOK_01414 5.9e-265 O Subtilase family
EJEMHCOK_01415 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
EJEMHCOK_01416 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EJEMHCOK_01417 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJEMHCOK_01418 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EJEMHCOK_01419 3.4e-58 L Transposase
EJEMHCOK_01420 6.4e-24 relB L RelB antitoxin
EJEMHCOK_01421 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
EJEMHCOK_01422 2.9e-66 gsiA P ATPase activity
EJEMHCOK_01423 2.9e-257 G Major Facilitator Superfamily
EJEMHCOK_01424 8.6e-159 K -acetyltransferase
EJEMHCOK_01425 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
EJEMHCOK_01426 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
EJEMHCOK_01427 5.2e-270 KLT Protein tyrosine kinase
EJEMHCOK_01428 0.0 S Fibronectin type 3 domain
EJEMHCOK_01429 1.4e-232 S ATPase family associated with various cellular activities (AAA)
EJEMHCOK_01430 1.7e-230 S Protein of unknown function DUF58
EJEMHCOK_01431 0.0 E Transglutaminase-like superfamily
EJEMHCOK_01432 5.7e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
EJEMHCOK_01433 2.8e-68 B Belongs to the OprB family
EJEMHCOK_01434 7.2e-95 T Forkhead associated domain
EJEMHCOK_01435 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJEMHCOK_01436 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJEMHCOK_01437 4.8e-127 L PFAM Integrase catalytic
EJEMHCOK_01438 4.1e-127 L PFAM Integrase catalytic
EJEMHCOK_01439 2.1e-124 L IstB-like ATP binding protein
EJEMHCOK_01440 3.9e-46 L Transposase
EJEMHCOK_01441 1.2e-137 tnp7109-21 L Integrase core domain
EJEMHCOK_01442 1.3e-184 yfdH 2.4.2.53 GT2 M Glycosyltransferase like family 2
EJEMHCOK_01443 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
EJEMHCOK_01444 7.9e-29 I transferase activity, transferring acyl groups other than amino-acyl groups
EJEMHCOK_01445 9.9e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EJEMHCOK_01446 3.5e-103 T protein histidine kinase activity
EJEMHCOK_01447 2.3e-87 K LytTr DNA-binding domain
EJEMHCOK_01448 1e-47 S Protein of unknown function (DUF3073)
EJEMHCOK_01449 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EJEMHCOK_01450 3.9e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
EJEMHCOK_01451 5.2e-17 S Amidohydrolase family
EJEMHCOK_01452 1.5e-152 S Amidohydrolase family
EJEMHCOK_01453 0.0 yjjP S Threonine/Serine exporter, ThrE
EJEMHCOK_01454 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EJEMHCOK_01455 2.8e-238 yhjX EGP Major facilitator Superfamily
EJEMHCOK_01456 0.0 trxB1 1.8.1.9 C Thioredoxin domain
EJEMHCOK_01457 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
EJEMHCOK_01458 5.8e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EJEMHCOK_01459 4.7e-94 K helix_turn _helix lactose operon repressor
EJEMHCOK_01460 1.2e-241 ytfL P Transporter associated domain
EJEMHCOK_01461 1.3e-188 yddG EG EamA-like transporter family
EJEMHCOK_01462 1.9e-83 dps P Belongs to the Dps family
EJEMHCOK_01463 4.3e-135 S Protein of unknown function DUF45
EJEMHCOK_01464 5.2e-252 ulaA 2.7.1.194 S PTS system sugar-specific permease component
EJEMHCOK_01465 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
EJEMHCOK_01466 7.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EJEMHCOK_01467 5.1e-190 K helix_turn _helix lactose operon repressor
EJEMHCOK_01468 0.0 G Glycosyl hydrolase family 20, domain 2
EJEMHCOK_01471 0.0 3.2.1.55 GH51 G arabinose metabolic process
EJEMHCOK_01472 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EJEMHCOK_01473 2.5e-124 gntR K FCD
EJEMHCOK_01474 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EJEMHCOK_01476 1.4e-183 L Phage integrase family
EJEMHCOK_01478 2.7e-227
EJEMHCOK_01479 2.6e-185 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
EJEMHCOK_01480 5.1e-270 hsdBM 2.1.1.72 L Eco57I restriction-modification methylase
EJEMHCOK_01481 1e-114 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
EJEMHCOK_01482 9.6e-42 S Protein of unknown function (DUF2442)
EJEMHCOK_01483 1.4e-08 K helix_turn _helix lactose operon repressor
EJEMHCOK_01484 2.3e-228 I Serine aminopeptidase, S33
EJEMHCOK_01485 2.7e-187 K Periplasmic binding protein domain
EJEMHCOK_01486 4.6e-187 G Glycosyl hydrolases family 43
EJEMHCOK_01487 5.7e-21 abfA1 3.2.1.55 GH51 G arabinose metabolic process
EJEMHCOK_01488 6.7e-72 S Transmembrane domain of unknown function (DUF3566)
EJEMHCOK_01489 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EJEMHCOK_01490 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EJEMHCOK_01491 3.2e-93 S Protein of unknown function (DUF721)
EJEMHCOK_01492 4.7e-241 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EJEMHCOK_01493 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EJEMHCOK_01494 8.6e-298 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EJEMHCOK_01495 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
EJEMHCOK_01496 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
EJEMHCOK_01497 5e-93 jag S Putative single-stranded nucleic acids-binding domain
EJEMHCOK_01498 3.5e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EJEMHCOK_01499 3.8e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
EJEMHCOK_01500 5.2e-243 parB K Belongs to the ParB family
EJEMHCOK_01501 9e-204 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EJEMHCOK_01502 0.0 murJ KLT MviN-like protein
EJEMHCOK_01503 0.0 M Conserved repeat domain
EJEMHCOK_01504 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
EJEMHCOK_01505 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
EJEMHCOK_01506 6.7e-113 S LytR cell envelope-related transcriptional attenuator
EJEMHCOK_01507 6e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EJEMHCOK_01508 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EJEMHCOK_01509 2.9e-210 S G5
EJEMHCOK_01511 2.4e-150 O Thioredoxin
EJEMHCOK_01512 0.0 KLT Protein tyrosine kinase
EJEMHCOK_01513 4.5e-174 K Psort location Cytoplasmic, score
EJEMHCOK_01514 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
EJEMHCOK_01515 9.8e-100 L Helix-turn-helix domain
EJEMHCOK_01516 0.0 S LPXTG-motif cell wall anchor domain protein
EJEMHCOK_01517 6.1e-243 M LPXTG-motif cell wall anchor domain protein
EJEMHCOK_01518 4.5e-180 3.4.22.70 M Sortase family
EJEMHCOK_01519 1.2e-152
EJEMHCOK_01520 3.7e-260 KLT Domain of unknown function (DUF4032)
EJEMHCOK_01521 4.9e-174 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJEMHCOK_01523 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
EJEMHCOK_01524 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
EJEMHCOK_01525 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
EJEMHCOK_01526 0.0 yjcE P Sodium/hydrogen exchanger family
EJEMHCOK_01527 1e-144 ypfH S Phospholipase/Carboxylesterase
EJEMHCOK_01528 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EJEMHCOK_01529 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
EJEMHCOK_01530 3e-144 cobB2 K Sir2 family
EJEMHCOK_01531 1.3e-190 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJEMHCOK_01532 1.2e-155 sapF E ATPases associated with a variety of cellular activities
EJEMHCOK_01533 5.2e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
EJEMHCOK_01534 5.4e-162 EP Binding-protein-dependent transport system inner membrane component
EJEMHCOK_01535 4.6e-169 P Binding-protein-dependent transport system inner membrane component
EJEMHCOK_01536 1.3e-309 E ABC transporter, substrate-binding protein, family 5
EJEMHCOK_01537 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EJEMHCOK_01538 7e-275 G Bacterial extracellular solute-binding protein
EJEMHCOK_01539 1.1e-62 G carbohydrate transport
EJEMHCOK_01541 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EJEMHCOK_01542 2e-126 G ABC transporter permease
EJEMHCOK_01543 1.4e-189 K Periplasmic binding protein domain
EJEMHCOK_01544 7.7e-21 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
EJEMHCOK_01545 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
EJEMHCOK_01547 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EJEMHCOK_01548 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EJEMHCOK_01549 3.5e-274 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
EJEMHCOK_01550 4.9e-128 XK27_08050 O prohibitin homologues
EJEMHCOK_01551 9.9e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
EJEMHCOK_01552 9.8e-233 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EJEMHCOK_01553 6.2e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
EJEMHCOK_01554 1.4e-226 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EJEMHCOK_01555 0.0 macB_2 V ATPases associated with a variety of cellular activities
EJEMHCOK_01556 2.1e-33 ctpE P E1-E2 ATPase
EJEMHCOK_01557 6.4e-185 ctpE P E1-E2 ATPase
EJEMHCOK_01558 3.6e-93 K acetyltransferase
EJEMHCOK_01559 1.7e-79 EGP Major Facilitator Superfamily
EJEMHCOK_01560 8.4e-198 yghZ C Aldo/keto reductase family
EJEMHCOK_01561 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
EJEMHCOK_01562 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
EJEMHCOK_01563 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
EJEMHCOK_01564 5.3e-127 S Short repeat of unknown function (DUF308)
EJEMHCOK_01565 0.0 pepO 3.4.24.71 O Peptidase family M13
EJEMHCOK_01566 4.6e-120 L Single-strand binding protein family
EJEMHCOK_01567 2.4e-170
EJEMHCOK_01568 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EJEMHCOK_01570 3.1e-267 recD2 3.6.4.12 L PIF1-like helicase
EJEMHCOK_01571 1.2e-160 supH S Sucrose-6F-phosphate phosphohydrolase
EJEMHCOK_01572 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
EJEMHCOK_01573 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
EJEMHCOK_01574 4.1e-289 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EJEMHCOK_01575 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
EJEMHCOK_01576 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
EJEMHCOK_01577 9.2e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
EJEMHCOK_01578 1.2e-185 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EJEMHCOK_01579 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EJEMHCOK_01580 3.9e-36 rpmE J Binds the 23S rRNA
EJEMHCOK_01582 4.4e-194 K helix_turn_helix, arabinose operon control protein
EJEMHCOK_01583 7.7e-163 glcU G Sugar transport protein
EJEMHCOK_01584 9.8e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
EJEMHCOK_01585 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
EJEMHCOK_01586 1.5e-108
EJEMHCOK_01587 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
EJEMHCOK_01588 7.9e-141 3.5.2.6 V Beta-lactamase enzyme family
EJEMHCOK_01589 7.2e-310 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
EJEMHCOK_01590 9.4e-164 EG EamA-like transporter family
EJEMHCOK_01592 2e-125 V FtsX-like permease family
EJEMHCOK_01593 2e-147 S Sulfite exporter TauE/SafE
EJEMHCOK_01595 1.9e-26 L Transposase
EJEMHCOK_01596 1.3e-215 MA20_36090 S Psort location Cytoplasmic, score 8.87
EJEMHCOK_01597 6.3e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
EJEMHCOK_01598 9.3e-36 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
EJEMHCOK_01599 1.7e-76 EGP Major facilitator superfamily
EJEMHCOK_01600 3.7e-179 glkA 2.7.1.2 G ROK family
EJEMHCOK_01601 3.2e-300 S ATPases associated with a variety of cellular activities
EJEMHCOK_01602 1.8e-54 EGP Major facilitator Superfamily
EJEMHCOK_01603 2.4e-158 I alpha/beta hydrolase fold
EJEMHCOK_01604 2.3e-113 S Pyridoxamine 5'-phosphate oxidase
EJEMHCOK_01606 4.6e-76 S DUF218 domain
EJEMHCOK_01607 9.6e-40 S Protein of unknown function (DUF979)
EJEMHCOK_01608 6.7e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EJEMHCOK_01611 2e-126
EJEMHCOK_01612 1.8e-44 M domain, Protein
EJEMHCOK_01613 4e-19 M domain, Protein
EJEMHCOK_01614 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
EJEMHCOK_01615 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
EJEMHCOK_01616 7.1e-172 tesB I Thioesterase-like superfamily
EJEMHCOK_01617 1.3e-77 S Protein of unknown function (DUF3180)
EJEMHCOK_01618 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EJEMHCOK_01619 1.8e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EJEMHCOK_01620 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
EJEMHCOK_01621 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJEMHCOK_01622 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EJEMHCOK_01623 4.6e-213 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EJEMHCOK_01624 5.3e-262 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
EJEMHCOK_01625 4.3e-308
EJEMHCOK_01626 8.3e-168 natA V ATPases associated with a variety of cellular activities
EJEMHCOK_01627 8.2e-232 epsG M Glycosyl transferase family 21
EJEMHCOK_01628 1.3e-272 S AI-2E family transporter
EJEMHCOK_01629 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
EJEMHCOK_01630 4e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
EJEMHCOK_01633 1.8e-66 S Domain of unknown function (DUF4190)
EJEMHCOK_01634 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EJEMHCOK_01635 4.8e-176 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EJEMHCOK_01637 1.6e-22 S Helix-turn-helix domain
EJEMHCOK_01638 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
EJEMHCOK_01639 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EJEMHCOK_01640 1.8e-178 L Phage integrase family
EJEMHCOK_01641 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EJEMHCOK_01642 1.4e-84 argR K Regulates arginine biosynthesis genes
EJEMHCOK_01643 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EJEMHCOK_01644 1.2e-246 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
EJEMHCOK_01645 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EJEMHCOK_01646 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EJEMHCOK_01647 2.2e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EJEMHCOK_01648 2.5e-86
EJEMHCOK_01649 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
EJEMHCOK_01650 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EJEMHCOK_01651 4.6e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJEMHCOK_01652 1.3e-134 ybbL V ATPases associated with a variety of cellular activities
EJEMHCOK_01653 1.6e-135 ybbM V Uncharacterised protein family (UPF0014)
EJEMHCOK_01654 7e-43 IQ oxidoreductase activity
EJEMHCOK_01656 7.6e-100 K AraC-like ligand binding domain
EJEMHCOK_01657 2.4e-237 rutG F Permease family
EJEMHCOK_01658 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
EJEMHCOK_01659 3.9e-63 S Phospholipase/Carboxylesterase
EJEMHCOK_01660 6.5e-188 MA20_14895 S Conserved hypothetical protein 698
EJEMHCOK_01661 6.6e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
EJEMHCOK_01662 2.1e-117 3.1.3.27 E haloacid dehalogenase-like hydrolase
EJEMHCOK_01663 1.4e-289 2.4.1.166 GT2 M Glycosyltransferase like family 2
EJEMHCOK_01665 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
EJEMHCOK_01666 3.6e-125 ypfH S Phospholipase/Carboxylesterase
EJEMHCOK_01667 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EJEMHCOK_01668 1.5e-24
EJEMHCOK_01669 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EJEMHCOK_01670 2.8e-66 S Zincin-like metallopeptidase
EJEMHCOK_01671 8.2e-91 S Helix-turn-helix
EJEMHCOK_01672 3e-197 S Short C-terminal domain
EJEMHCOK_01673 2.7e-22
EJEMHCOK_01674 5.9e-148
EJEMHCOK_01675 7.7e-25 K Psort location Cytoplasmic, score
EJEMHCOK_01676 1.1e-43 K Psort location Cytoplasmic, score
EJEMHCOK_01677 7.2e-255 KLT Protein tyrosine kinase
EJEMHCOK_01678 1.6e-63 S Cupin 2, conserved barrel domain protein
EJEMHCOK_01679 3.6e-157 ksgA 2.1.1.182 J Methyltransferase domain
EJEMHCOK_01680 5.6e-59 yccF S Inner membrane component domain
EJEMHCOK_01681 3e-120 E Psort location Cytoplasmic, score 8.87
EJEMHCOK_01682 2.8e-246 XK27_00240 K Fic/DOC family
EJEMHCOK_01683 2.3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EJEMHCOK_01684 2.3e-226 mtnE 2.6.1.83 E Aminotransferase class I and II
EJEMHCOK_01685 3.8e-93 metI P Binding-protein-dependent transport system inner membrane component
EJEMHCOK_01686 3e-204 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EJEMHCOK_01687 1.3e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
EJEMHCOK_01688 7.7e-188 acoA 1.2.4.1 C Dehydrogenase E1 component
EJEMHCOK_01689 3.5e-146 P NLPA lipoprotein
EJEMHCOK_01690 1.6e-166 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
EJEMHCOK_01691 1.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EJEMHCOK_01692 9.3e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
EJEMHCOK_01693 1.6e-39 tcsS2 T Histidine kinase
EJEMHCOK_01694 3.2e-50 tcsS2 T Histidine kinase
EJEMHCOK_01695 2.9e-207 tcsS2 T Histidine kinase
EJEMHCOK_01696 6.1e-132 K helix_turn_helix, Lux Regulon
EJEMHCOK_01697 0.0 phoN I PAP2 superfamily
EJEMHCOK_01698 0.0 MV MacB-like periplasmic core domain
EJEMHCOK_01699 3.4e-162 V ABC transporter, ATP-binding protein
EJEMHCOK_01700 1.3e-251 metY 2.5.1.49 E Aminotransferase class-V
EJEMHCOK_01701 4.6e-157 S Putative ABC-transporter type IV
EJEMHCOK_01702 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
EJEMHCOK_01703 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
EJEMHCOK_01704 1.3e-57 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
EJEMHCOK_01705 1.1e-283 dprA 5.99.1.2 LU DNA recombination-mediator protein A
EJEMHCOK_01706 3.6e-293 comM O Magnesium chelatase, subunit ChlI C-terminal
EJEMHCOK_01707 1.1e-70 yraN L Belongs to the UPF0102 family
EJEMHCOK_01708 5.6e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
EJEMHCOK_01709 5.7e-118 safC S O-methyltransferase
EJEMHCOK_01710 7.9e-166 fmt2 3.2.2.10 S Belongs to the LOG family
EJEMHCOK_01711 4.5e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EJEMHCOK_01712 6.5e-234 patB 4.4.1.8 E Aminotransferase, class I II
EJEMHCOK_01715 1.3e-243 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EJEMHCOK_01716 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EJEMHCOK_01717 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EJEMHCOK_01718 6.7e-254 clcA_2 P Voltage gated chloride channel
EJEMHCOK_01719 8.1e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EJEMHCOK_01720 3.3e-247 rnd 3.1.13.5 J 3'-5' exonuclease
EJEMHCOK_01721 3.7e-113 S Protein of unknown function (DUF3000)
EJEMHCOK_01722 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EJEMHCOK_01723 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
EJEMHCOK_01724 3.5e-38
EJEMHCOK_01725 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJEMHCOK_01726 8.6e-223 S Peptidase dimerisation domain
EJEMHCOK_01727 2.2e-91 P ABC-type metal ion transport system permease component
EJEMHCOK_01728 1.4e-166 S Sucrose-6F-phosphate phosphohydrolase
EJEMHCOK_01729 1.1e-176 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJEMHCOK_01730 2.3e-34
EJEMHCOK_01731 6.3e-50
EJEMHCOK_01732 2.1e-131
EJEMHCOK_01733 5.5e-118
EJEMHCOK_01734 1.2e-28
EJEMHCOK_01735 7.7e-184 S Helix-turn-helix domain
EJEMHCOK_01736 2.5e-42
EJEMHCOK_01737 1.7e-90 S Transcription factor WhiB
EJEMHCOK_01738 8.2e-117 parA D AAA domain
EJEMHCOK_01739 4.6e-236 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJEMHCOK_01740 7.1e-39
EJEMHCOK_01741 3.5e-30
EJEMHCOK_01742 0.0 U Type IV secretory system Conjugative DNA transfer
EJEMHCOK_01743 3e-09
EJEMHCOK_01744 2.4e-101 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
EJEMHCOK_01745 5.9e-101 K DNA binding
EJEMHCOK_01746 1.6e-128
EJEMHCOK_01747 3.6e-14 U Type IV secretory system Conjugative DNA transfer
EJEMHCOK_01748 1.7e-206 isp2 3.2.1.96 M CHAP domain
EJEMHCOK_01749 0.0 trsE U type IV secretory pathway VirB4
EJEMHCOK_01750 4e-62 S PrgI family protein
EJEMHCOK_01751 3.3e-139
EJEMHCOK_01752 8.9e-26
EJEMHCOK_01753 0.0 XK27_00515 D Cell surface antigen C-terminus
EJEMHCOK_01754 1.2e-282 S Uncharacterized protein conserved in bacteria (DUF2252)
EJEMHCOK_01755 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
EJEMHCOK_01756 9.4e-253 S Domain of unknown function (DUF5067)
EJEMHCOK_01757 1.3e-60 EGP Major facilitator Superfamily
EJEMHCOK_01758 2.2e-177 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EJEMHCOK_01759 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
EJEMHCOK_01760 1.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
EJEMHCOK_01761 2.6e-169
EJEMHCOK_01762 2e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EJEMHCOK_01763 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
EJEMHCOK_01764 1e-165 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EJEMHCOK_01765 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EJEMHCOK_01766 6.1e-45 M Lysin motif
EJEMHCOK_01767 2.3e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EJEMHCOK_01768 6.4e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
EJEMHCOK_01769 0.0 L DNA helicase
EJEMHCOK_01770 1.3e-90 mraZ K Belongs to the MraZ family
EJEMHCOK_01771 7.1e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EJEMHCOK_01772 5.6e-42 tnp7109-21 L Integrase core domain
EJEMHCOK_01773 4.4e-106
EJEMHCOK_01774 9.5e-197 M Glycosyltransferase like family 2
EJEMHCOK_01775 3.7e-165 L PFAM Integrase catalytic
EJEMHCOK_01776 1.8e-150 L IstB-like ATP binding protein
EJEMHCOK_01777 4.1e-144 L IstB-like ATP binding protein
EJEMHCOK_01778 1.7e-298 L PFAM Integrase catalytic
EJEMHCOK_01779 4e-161 L PFAM Integrase catalytic
EJEMHCOK_01780 2.3e-26 L PFAM Integrase catalytic
EJEMHCOK_01781 3e-81 L PFAM Integrase catalytic
EJEMHCOK_01782 7.5e-82 L transposase activity
EJEMHCOK_01783 2.6e-73 1.1.1.339 GM NAD dependent epimerase/dehydratase family
EJEMHCOK_01784 7.1e-192 I Acyltransferase family
EJEMHCOK_01785 0.0 rgpF M Rhamnan synthesis protein F
EJEMHCOK_01786 2.4e-272 S Polysaccharide pyruvyl transferase
EJEMHCOK_01787 6.3e-280 S Glucosyl transferase GtrII
EJEMHCOK_01788 1.6e-41 L PFAM Integrase catalytic
EJEMHCOK_01789 2.4e-25 L PFAM Integrase catalytic
EJEMHCOK_01790 4e-242 rgpD 3.6.3.38, 3.6.3.40 GM ABC transporter, ATP-binding protein
EJEMHCOK_01791 1.4e-153 rgpC U Transport permease protein
EJEMHCOK_01792 1e-206 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EJEMHCOK_01793 3.9e-265 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EJEMHCOK_01794 4.1e-172 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EJEMHCOK_01795 3.7e-38 L Transposase
EJEMHCOK_01796 2.5e-11 L Transposase
EJEMHCOK_01797 3.2e-22
EJEMHCOK_01798 2.9e-55 L transposase activity
EJEMHCOK_01799 4.8e-20 ytrE V ABC transporter
EJEMHCOK_01800 2.2e-177 V N-Acetylmuramoyl-L-alanine amidase
EJEMHCOK_01801 2.2e-95
EJEMHCOK_01802 3.9e-119 K Transcriptional regulatory protein, C terminal
EJEMHCOK_01803 4e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EJEMHCOK_01804 1e-183 lacR K Transcriptional regulator, LacI family
EJEMHCOK_01805 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
EJEMHCOK_01806 1.7e-72
EJEMHCOK_01807 9.6e-157 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)