ORF_ID e_value Gene_name EC_number CAZy COGs Description
JPCLEFIL_00005 5.6e-07
JPCLEFIL_00009 3.9e-10 K Cro/C1-type HTH DNA-binding domain
JPCLEFIL_00011 7.4e-23 K Helix-turn-helix domain
JPCLEFIL_00013 2e-41
JPCLEFIL_00014 2.4e-23
JPCLEFIL_00015 1.6e-181 I Pfam Lipase (class 3)
JPCLEFIL_00016 1.9e-27 S Protein of unknown function (DUF1433)
JPCLEFIL_00018 2.7e-160 S aspartate phosphatase
JPCLEFIL_00020 5.1e-11
JPCLEFIL_00021 0.0 S Pfam Transposase IS66
JPCLEFIL_00022 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JPCLEFIL_00023 1.2e-32 L GIY-YIG catalytic domain
JPCLEFIL_00024 2.4e-47 L Phage integrase, N-terminal SAM-like domain
JPCLEFIL_00025 5e-114 T Nacht domain
JPCLEFIL_00027 2.8e-08
JPCLEFIL_00028 8.5e-55
JPCLEFIL_00029 1e-10 S Phage uncharacterised protein (Phage_XkdX)
JPCLEFIL_00031 3.8e-49 S Domain of unknown function (DUF2479)
JPCLEFIL_00034 4.3e-191
JPCLEFIL_00035 8.8e-132 KL Phage plasmid primase P4 family
JPCLEFIL_00036 5.6e-48
JPCLEFIL_00046 1.6e-219 glcP G Major Facilitator Superfamily
JPCLEFIL_00047 1.6e-246 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JPCLEFIL_00048 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
JPCLEFIL_00049 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
JPCLEFIL_00050 5.1e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
JPCLEFIL_00051 1.5e-172 ybaS 1.1.1.58 S Na -dependent transporter
JPCLEFIL_00052 6e-108 ybbA S Putative esterase
JPCLEFIL_00053 6.1e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_00054 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_00055 2e-172 feuA P Iron-uptake system-binding protein
JPCLEFIL_00056 1.3e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
JPCLEFIL_00057 2.5e-236 ybbC 3.2.1.52 S protein conserved in bacteria
JPCLEFIL_00058 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
JPCLEFIL_00059 2e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
JPCLEFIL_00060 4.6e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JPCLEFIL_00061 2.9e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JPCLEFIL_00062 7.7e-85 ybbJ J acetyltransferase
JPCLEFIL_00063 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
JPCLEFIL_00069 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
JPCLEFIL_00070 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
JPCLEFIL_00071 1.8e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JPCLEFIL_00072 1.3e-223 ybbR S protein conserved in bacteria
JPCLEFIL_00073 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JPCLEFIL_00074 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JPCLEFIL_00075 9.3e-153 V ATPases associated with a variety of cellular activities
JPCLEFIL_00076 3.7e-106 S ABC-2 family transporter protein
JPCLEFIL_00077 4e-276 KLT Protein kinase domain
JPCLEFIL_00079 2.8e-90 H Tellurite resistance protein TehB
JPCLEFIL_00080 2.4e-161 dkgB S Aldo/keto reductase family
JPCLEFIL_00081 2.9e-93 yxaC M effector of murein hydrolase
JPCLEFIL_00082 6.9e-52 S LrgA family
JPCLEFIL_00083 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_00084 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
JPCLEFIL_00085 3.3e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JPCLEFIL_00086 6.2e-104 T Histidine kinase
JPCLEFIL_00087 3.8e-82 KT helix_turn_helix, Lux Regulon
JPCLEFIL_00088 3.5e-134 V ABC transporter, ATP-binding protein
JPCLEFIL_00089 2.3e-146 V ABC-2 type transporter
JPCLEFIL_00090 6e-123 V ABC-2 type transporter
JPCLEFIL_00091 4.4e-14
JPCLEFIL_00092 8.1e-59 bacT Q Thioesterase domain
JPCLEFIL_00093 1.5e-68 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_00094 2.4e-253 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_00095 6.9e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
JPCLEFIL_00096 1.7e-178 yuaG 3.4.21.72 S protein conserved in bacteria
JPCLEFIL_00097 4.7e-83 yuaF OU Membrane protein implicated in regulation of membrane protease activity
JPCLEFIL_00098 2e-72 yuaE S DinB superfamily
JPCLEFIL_00099 2.5e-109 yuaD S MOSC domain
JPCLEFIL_00100 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
JPCLEFIL_00101 1.2e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
JPCLEFIL_00102 4.3e-95 yuaC K Belongs to the GbsR family
JPCLEFIL_00103 7.9e-94 yuaB
JPCLEFIL_00104 3.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
JPCLEFIL_00105 1.5e-144 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JPCLEFIL_00106 2.5e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JPCLEFIL_00107 3.5e-117 G Cupin
JPCLEFIL_00108 3.4e-52 yjcN
JPCLEFIL_00112 9.3e-46 S Aspartate phosphatase response regulator
JPCLEFIL_00113 1.2e-105 S Aspartate phosphatase response regulator
JPCLEFIL_00114 1.5e-13
JPCLEFIL_00116 5e-17
JPCLEFIL_00118 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JPCLEFIL_00119 2.9e-194 yubA S transporter activity
JPCLEFIL_00120 2.1e-185 ygjR S Oxidoreductase
JPCLEFIL_00121 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
JPCLEFIL_00122 2.6e-235 mcpA NT chemotaxis protein
JPCLEFIL_00123 6e-224 mcpA NT chemotaxis protein
JPCLEFIL_00124 1.5e-235 mcpA NT chemotaxis protein
JPCLEFIL_00125 2.4e-220 mcpA NT chemotaxis protein
JPCLEFIL_00126 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
JPCLEFIL_00127 1.4e-40
JPCLEFIL_00128 5.6e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
JPCLEFIL_00129 2e-73 yugU S Uncharacterised protein family UPF0047
JPCLEFIL_00130 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
JPCLEFIL_00131 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
JPCLEFIL_00132 8.3e-117 yugP S Zn-dependent protease
JPCLEFIL_00133 3.4e-18
JPCLEFIL_00134 6.7e-27 mstX S Membrane-integrating protein Mistic
JPCLEFIL_00135 1.2e-180 yugO P COG1226 Kef-type K transport systems
JPCLEFIL_00136 7e-71 yugN S YugN-like family
JPCLEFIL_00138 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
JPCLEFIL_00139 4.1e-93 S NADPH-dependent FMN reductase
JPCLEFIL_00140 7.1e-118 ycaC Q Isochorismatase family
JPCLEFIL_00141 1.8e-228 yugK C Dehydrogenase
JPCLEFIL_00142 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
JPCLEFIL_00143 1.8e-34 yuzA S Domain of unknown function (DUF378)
JPCLEFIL_00144 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
JPCLEFIL_00145 1.6e-208 yugH 2.6.1.1 E Aminotransferase
JPCLEFIL_00146 2e-83 alaR K Transcriptional regulator
JPCLEFIL_00147 5.5e-155 yugF I Hydrolase
JPCLEFIL_00148 1.4e-40 yugE S Domain of unknown function (DUF1871)
JPCLEFIL_00149 3.3e-222 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JPCLEFIL_00150 4.7e-230 T PhoQ Sensor
JPCLEFIL_00151 7.7e-67 kapB G Kinase associated protein B
JPCLEFIL_00152 4e-118 kapD L the KinA pathway to sporulation
JPCLEFIL_00153 4.5e-185 yuxJ EGP Major facilitator Superfamily
JPCLEFIL_00154 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
JPCLEFIL_00155 2.2e-72 yuxK S protein conserved in bacteria
JPCLEFIL_00156 9.3e-74 yufK S Family of unknown function (DUF5366)
JPCLEFIL_00157 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JPCLEFIL_00158 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
JPCLEFIL_00159 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JPCLEFIL_00160 2.8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JPCLEFIL_00161 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
JPCLEFIL_00162 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
JPCLEFIL_00163 2.3e-12
JPCLEFIL_00164 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JPCLEFIL_00165 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JPCLEFIL_00166 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JPCLEFIL_00167 1.7e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JPCLEFIL_00168 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JPCLEFIL_00169 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JPCLEFIL_00170 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
JPCLEFIL_00171 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
JPCLEFIL_00172 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPCLEFIL_00173 7.3e-124 comP 2.7.13.3 T Histidine kinase
JPCLEFIL_00174 3.6e-120 comP 2.7.13.3 T Histidine kinase
JPCLEFIL_00176 4.4e-62 comQ H Polyprenyl synthetase
JPCLEFIL_00179 1.2e-50 yuzC
JPCLEFIL_00180 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
JPCLEFIL_00181 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JPCLEFIL_00182 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
JPCLEFIL_00183 7.2e-68 yueI S Protein of unknown function (DUF1694)
JPCLEFIL_00184 2.8e-38 yueH S YueH-like protein
JPCLEFIL_00185 6.4e-34 yueG S Spore germination protein gerPA/gerPF
JPCLEFIL_00186 4.7e-186 yueF S transporter activity
JPCLEFIL_00187 1.6e-22 S Protein of unknown function (DUF2642)
JPCLEFIL_00188 8.3e-96 yueE S phosphohydrolase
JPCLEFIL_00189 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_00190 1.3e-76 yueC S Family of unknown function (DUF5383)
JPCLEFIL_00191 0.0 esaA S type VII secretion protein EsaA
JPCLEFIL_00192 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
JPCLEFIL_00193 3.4e-204 essB S WXG100 protein secretion system (Wss), protein YukC
JPCLEFIL_00194 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
JPCLEFIL_00195 3.3e-46 esxA S Belongs to the WXG100 family
JPCLEFIL_00196 9.5e-228 yukF QT Transcriptional regulator
JPCLEFIL_00197 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
JPCLEFIL_00198 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
JPCLEFIL_00199 1.1e-33 mbtH S MbtH-like protein
JPCLEFIL_00200 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_00201 8e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
JPCLEFIL_00202 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
JPCLEFIL_00203 8.6e-218 entC 5.4.4.2 HQ Isochorismate synthase
JPCLEFIL_00204 1.8e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JPCLEFIL_00205 1.4e-164 besA S Putative esterase
JPCLEFIL_00206 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
JPCLEFIL_00207 1.5e-101 bioY S Biotin biosynthesis protein
JPCLEFIL_00208 3.4e-207 yuiF S antiporter
JPCLEFIL_00209 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JPCLEFIL_00210 1.6e-77 yuiD S protein conserved in bacteria
JPCLEFIL_00211 4.6e-117 yuiC S protein conserved in bacteria
JPCLEFIL_00212 9.9e-28 yuiB S Putative membrane protein
JPCLEFIL_00213 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
JPCLEFIL_00214 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
JPCLEFIL_00216 1.1e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JPCLEFIL_00217 4.8e-29
JPCLEFIL_00218 2.9e-69 CP Membrane
JPCLEFIL_00219 1.5e-121 V ABC transporter
JPCLEFIL_00221 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
JPCLEFIL_00223 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
JPCLEFIL_00224 1.1e-62 erpA S Belongs to the HesB IscA family
JPCLEFIL_00225 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JPCLEFIL_00226 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JPCLEFIL_00227 2.4e-39 yuzB S Belongs to the UPF0349 family
JPCLEFIL_00228 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
JPCLEFIL_00229 1.1e-53 yuzD S protein conserved in bacteria
JPCLEFIL_00230 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
JPCLEFIL_00231 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
JPCLEFIL_00232 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JPCLEFIL_00233 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JPCLEFIL_00234 3e-240 hom 1.1.1.3 E homoserine dehydrogenase
JPCLEFIL_00235 1.9e-194 yutH S Spore coat protein
JPCLEFIL_00236 3.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JPCLEFIL_00237 3.6e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JPCLEFIL_00238 6.8e-72 yutE S Protein of unknown function DUF86
JPCLEFIL_00239 1.7e-47 yutD S protein conserved in bacteria
JPCLEFIL_00240 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JPCLEFIL_00241 6.6e-192 lytH M Peptidase, M23
JPCLEFIL_00242 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
JPCLEFIL_00243 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JPCLEFIL_00244 1.1e-144 yunE S membrane transporter protein
JPCLEFIL_00245 1.5e-168 yunF S Protein of unknown function DUF72
JPCLEFIL_00246 2.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
JPCLEFIL_00247 4.2e-261 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
JPCLEFIL_00248 1.5e-302 pucR QT COG2508 Regulator of polyketide synthase expression
JPCLEFIL_00249 7.9e-21 yqbD 2.1.1.72 L Putative phage serine protease XkdF
JPCLEFIL_00250 2.2e-20
JPCLEFIL_00252 1.9e-212 blt EGP Major facilitator Superfamily
JPCLEFIL_00253 1.3e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
JPCLEFIL_00254 5.2e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
JPCLEFIL_00255 1.6e-165 bsn L Ribonuclease
JPCLEFIL_00256 1.2e-205 msmX P Belongs to the ABC transporter superfamily
JPCLEFIL_00257 3.6e-134 yurK K UTRA
JPCLEFIL_00258 9e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
JPCLEFIL_00259 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
JPCLEFIL_00260 9.8e-158 yurN G Binding-protein-dependent transport system inner membrane component
JPCLEFIL_00261 3.7e-243 yurO G COG1653 ABC-type sugar transport system, periplasmic component
JPCLEFIL_00262 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
JPCLEFIL_00263 5e-165 K helix_turn_helix, mercury resistance
JPCLEFIL_00265 4.5e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
JPCLEFIL_00266 2e-200 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
JPCLEFIL_00267 7.4e-25 yncE S Protein of unknown function (DUF2691)
JPCLEFIL_00268 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
JPCLEFIL_00269 8.7e-270 sufB O FeS cluster assembly
JPCLEFIL_00270 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
JPCLEFIL_00271 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JPCLEFIL_00272 1.2e-244 sufD O assembly protein SufD
JPCLEFIL_00273 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JPCLEFIL_00274 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JPCLEFIL_00275 3e-145 metQ P Belongs to the NlpA lipoprotein family
JPCLEFIL_00276 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
JPCLEFIL_00277 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JPCLEFIL_00278 1.5e-56 yusD S SCP-2 sterol transfer family
JPCLEFIL_00279 1.6e-54 yusE CO Thioredoxin
JPCLEFIL_00280 1.4e-62 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
JPCLEFIL_00281 3.7e-40 yusG S Protein of unknown function (DUF2553)
JPCLEFIL_00282 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
JPCLEFIL_00283 6.2e-63 arsC 1.20.4.1 P Belongs to the ArsC family
JPCLEFIL_00284 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
JPCLEFIL_00285 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
JPCLEFIL_00286 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
JPCLEFIL_00287 1.4e-164 fadM E Proline dehydrogenase
JPCLEFIL_00288 1.5e-209 yusP P Major facilitator superfamily
JPCLEFIL_00289 5.7e-42
JPCLEFIL_00290 1.1e-53 yusN M Coat F domain
JPCLEFIL_00291 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
JPCLEFIL_00292 8.1e-288 yusP P Major facilitator superfamily
JPCLEFIL_00293 5.5e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
JPCLEFIL_00294 4.9e-185 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JPCLEFIL_00295 3.3e-39 yusU S Protein of unknown function (DUF2573)
JPCLEFIL_00296 3.1e-150 yusV 3.6.3.34 HP ABC transporter
JPCLEFIL_00297 7.2e-45 S YusW-like protein
JPCLEFIL_00298 0.0 pepF2 E COG1164 Oligoendopeptidase F
JPCLEFIL_00299 2.3e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JPCLEFIL_00300 4.7e-79 dps P Belongs to the Dps family
JPCLEFIL_00301 1.9e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JPCLEFIL_00302 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_00303 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
JPCLEFIL_00304 3.4e-24
JPCLEFIL_00305 2.9e-157 yuxN K Transcriptional regulator
JPCLEFIL_00306 3.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JPCLEFIL_00307 6.6e-24 S Protein of unknown function (DUF3970)
JPCLEFIL_00308 1.2e-258 gerAA EG Spore germination protein
JPCLEFIL_00309 3.6e-186 gerAB E Spore germination protein
JPCLEFIL_00310 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
JPCLEFIL_00311 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPCLEFIL_00312 2.3e-193 vraS 2.7.13.3 T Histidine kinase
JPCLEFIL_00313 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
JPCLEFIL_00314 3.3e-126 liaG S Putative adhesin
JPCLEFIL_00315 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
JPCLEFIL_00316 5.3e-44 liaI S membrane
JPCLEFIL_00317 2.4e-226 yvqJ EGP Major facilitator Superfamily
JPCLEFIL_00318 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
JPCLEFIL_00319 1.2e-219 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
JPCLEFIL_00320 2e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_00321 1.2e-166 yvrC P ABC transporter substrate-binding protein
JPCLEFIL_00322 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JPCLEFIL_00323 1.1e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
JPCLEFIL_00324 0.0 T PhoQ Sensor
JPCLEFIL_00325 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_00326 1.1e-36
JPCLEFIL_00327 3.8e-102 yvrI K RNA polymerase
JPCLEFIL_00328 6.1e-15 S YvrJ protein family
JPCLEFIL_00329 7.8e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
JPCLEFIL_00330 1e-64 yvrL S Regulatory protein YrvL
JPCLEFIL_00331 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
JPCLEFIL_00332 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_00333 9.5e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_00334 1.2e-177 fhuD P ABC transporter
JPCLEFIL_00335 1.7e-125 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JPCLEFIL_00336 7e-235 yvsH E Arginine ornithine antiporter
JPCLEFIL_00337 5.2e-13 S Small spore protein J (Spore_SspJ)
JPCLEFIL_00338 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
JPCLEFIL_00339 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JPCLEFIL_00340 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
JPCLEFIL_00341 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
JPCLEFIL_00342 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
JPCLEFIL_00343 7.3e-113 yfiK K Regulator
JPCLEFIL_00344 4.3e-179 T Histidine kinase
JPCLEFIL_00345 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
JPCLEFIL_00346 1.3e-191 yfiM V ABC-2 type transporter
JPCLEFIL_00347 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
JPCLEFIL_00348 5e-156 yvgN S reductase
JPCLEFIL_00349 2.7e-85 yvgO
JPCLEFIL_00350 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
JPCLEFIL_00351 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
JPCLEFIL_00352 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JPCLEFIL_00353 0.0 helD 3.6.4.12 L DNA helicase
JPCLEFIL_00354 3.5e-106 yvgT S membrane
JPCLEFIL_00355 2e-141 S Metallo-peptidase family M12
JPCLEFIL_00356 1e-72 bdbC O Required for disulfide bond formation in some proteins
JPCLEFIL_00357 7.7e-99 bdbD O Thioredoxin
JPCLEFIL_00358 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JPCLEFIL_00359 0.0 copA 3.6.3.54 P P-type ATPase
JPCLEFIL_00360 2.2e-28 copZ P Heavy-metal-associated domain
JPCLEFIL_00361 1.4e-47 csoR S transcriptional
JPCLEFIL_00362 1.2e-191 yvaA 1.1.1.371 S Oxidoreductase
JPCLEFIL_00363 2.5e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JPCLEFIL_00364 7e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPCLEFIL_00365 9.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
JPCLEFIL_00366 2.4e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPCLEFIL_00367 1e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JPCLEFIL_00368 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
JPCLEFIL_00369 1.7e-120 tcyL P Binding-protein-dependent transport system inner membrane component
JPCLEFIL_00370 3e-145 tcyK M Bacterial periplasmic substrate-binding proteins
JPCLEFIL_00371 3.3e-128 ytmJ ET Bacterial periplasmic substrate-binding proteins
JPCLEFIL_00372 3e-101 ytmI K Acetyltransferase (GNAT) domain
JPCLEFIL_00373 3.8e-162 ytlI K LysR substrate binding domain
JPCLEFIL_00374 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JPCLEFIL_00375 3.7e-48 yrdF K ribonuclease inhibitor
JPCLEFIL_00377 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JPCLEFIL_00378 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JPCLEFIL_00379 1.6e-142 est 3.1.1.1 S Carboxylesterase
JPCLEFIL_00380 4.8e-24 secG U Preprotein translocase subunit SecG
JPCLEFIL_00381 6e-35 yvzC K Transcriptional
JPCLEFIL_00382 2.3e-69 K transcriptional
JPCLEFIL_00383 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
JPCLEFIL_00384 8.8e-53 yodB K transcriptional
JPCLEFIL_00385 2.6e-258 T His Kinase A (phosphoacceptor) domain
JPCLEFIL_00386 1.4e-121 K Transcriptional regulatory protein, C terminal
JPCLEFIL_00387 2.2e-137 mutG S ABC-2 family transporter protein
JPCLEFIL_00388 8.4e-123 spaE S ABC-2 family transporter protein
JPCLEFIL_00389 1.2e-126 mutF V ABC transporter, ATP-binding protein
JPCLEFIL_00390 5.2e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JPCLEFIL_00391 3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JPCLEFIL_00392 1.2e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JPCLEFIL_00393 2.9e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JPCLEFIL_00394 4.3e-76 yvbF K Belongs to the GbsR family
JPCLEFIL_00395 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JPCLEFIL_00396 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JPCLEFIL_00397 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JPCLEFIL_00398 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JPCLEFIL_00399 3.5e-97 yvbF K Belongs to the GbsR family
JPCLEFIL_00400 9.8e-104 yvbG U UPF0056 membrane protein
JPCLEFIL_00401 4.2e-119 exoY M Membrane
JPCLEFIL_00402 0.0 tcaA S response to antibiotic
JPCLEFIL_00403 1.5e-80 yvbK 3.1.3.25 K acetyltransferase
JPCLEFIL_00406 5.8e-196 3.6.3.27 V Peptidase C39 family
JPCLEFIL_00407 2.6e-191 lcnDR2 V Lanthionine synthetase C-like protein
JPCLEFIL_00409 6.3e-212 lcnDR2 V Lanthionine synthetase C-like protein
JPCLEFIL_00411 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JPCLEFIL_00412 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
JPCLEFIL_00413 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JPCLEFIL_00414 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JPCLEFIL_00415 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JPCLEFIL_00416 2.6e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JPCLEFIL_00418 7.4e-253 araE EGP Major facilitator Superfamily
JPCLEFIL_00419 2.5e-203 araR K transcriptional
JPCLEFIL_00420 8.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPCLEFIL_00422 5.3e-156 yvbU K Transcriptional regulator
JPCLEFIL_00423 7.7e-158 yvbV EG EamA-like transporter family
JPCLEFIL_00424 1.1e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
JPCLEFIL_00425 4.2e-258
JPCLEFIL_00426 2.1e-182 purR7 5.1.1.1 K Transcriptional regulator
JPCLEFIL_00427 3.4e-115 yyaS S Membrane
JPCLEFIL_00428 7e-164 3.1.3.104 S hydrolases of the HAD superfamily
JPCLEFIL_00429 1.2e-149 ybbH_1 K RpiR family transcriptional regulator
JPCLEFIL_00430 3e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
JPCLEFIL_00431 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
JPCLEFIL_00432 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JPCLEFIL_00433 2.8e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
JPCLEFIL_00434 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JPCLEFIL_00435 1.6e-219 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JPCLEFIL_00436 6.6e-120 yvfI K COG2186 Transcriptional regulators
JPCLEFIL_00437 3.8e-304 yvfH C L-lactate permease
JPCLEFIL_00438 1.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
JPCLEFIL_00439 2.7e-32 yvfG S YvfG protein
JPCLEFIL_00440 1e-184 yvfF GM Exopolysaccharide biosynthesis protein
JPCLEFIL_00441 2e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
JPCLEFIL_00442 4.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
JPCLEFIL_00443 1.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JPCLEFIL_00444 5.3e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JPCLEFIL_00445 2e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
JPCLEFIL_00446 6.4e-204 epsI GM pyruvyl transferase
JPCLEFIL_00447 1.9e-192 epsH GT2 S Glycosyltransferase like family 2
JPCLEFIL_00448 7.7e-205 epsG S EpsG family
JPCLEFIL_00449 5.1e-212 epsF GT4 M Glycosyl transferases group 1
JPCLEFIL_00450 2.6e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JPCLEFIL_00451 3.3e-219 epsD GT4 M Glycosyl transferase 4-like
JPCLEFIL_00452 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
JPCLEFIL_00453 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
JPCLEFIL_00454 1.6e-118 ywqC M biosynthesis protein
JPCLEFIL_00455 1.9e-77 slr K transcriptional
JPCLEFIL_00456 1.9e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
JPCLEFIL_00458 3.7e-96 ywjB H RibD C-terminal domain
JPCLEFIL_00459 1.3e-111 yyaS S Membrane
JPCLEFIL_00460 3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPCLEFIL_00461 1.6e-93 padC Q Phenolic acid decarboxylase
JPCLEFIL_00462 1.7e-15 S Protein of unknown function (DUF1433)
JPCLEFIL_00463 2.2e-17 S Protein of unknown function (DUF1433)
JPCLEFIL_00464 9.8e-18 S Protein of unknown function (DUF1433)
JPCLEFIL_00465 5.4e-267 I Pfam Lipase (class 3)
JPCLEFIL_00466 5.8e-33
JPCLEFIL_00468 1.5e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
JPCLEFIL_00469 4.7e-219 rafB P LacY proton/sugar symporter
JPCLEFIL_00470 1.9e-183 scrR K transcriptional
JPCLEFIL_00471 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JPCLEFIL_00472 3.7e-162 yraN K Transcriptional regulator
JPCLEFIL_00473 1.4e-209 yraM S PrpF protein
JPCLEFIL_00474 2.1e-247 EGP Sugar (and other) transporter
JPCLEFIL_00475 5.3e-11 yvdD 3.2.2.10 S Belongs to the LOG family
JPCLEFIL_00476 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
JPCLEFIL_00477 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
JPCLEFIL_00478 2.8e-280 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
JPCLEFIL_00479 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JPCLEFIL_00480 7.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JPCLEFIL_00481 8.2e-79 M Ribonuclease
JPCLEFIL_00482 7.8e-28 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
JPCLEFIL_00483 4.4e-21
JPCLEFIL_00484 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
JPCLEFIL_00485 4.7e-36 crh G Phosphocarrier protein Chr
JPCLEFIL_00486 5.3e-170 whiA K May be required for sporulation
JPCLEFIL_00487 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JPCLEFIL_00488 1.1e-166 rapZ S Displays ATPase and GTPase activities
JPCLEFIL_00489 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JPCLEFIL_00490 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JPCLEFIL_00491 5.2e-121 usp CBM50 M protein conserved in bacteria
JPCLEFIL_00492 8.4e-276 S COG0457 FOG TPR repeat
JPCLEFIL_00493 2.3e-190 sasA T Histidine kinase
JPCLEFIL_00494 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_00495 1.5e-53
JPCLEFIL_00496 0.0 msbA2 3.6.3.44 V ABC transporter
JPCLEFIL_00497 2.4e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
JPCLEFIL_00498 1.7e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JPCLEFIL_00499 7.6e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JPCLEFIL_00500 1.6e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JPCLEFIL_00501 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JPCLEFIL_00502 2.6e-231 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JPCLEFIL_00503 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JPCLEFIL_00504 3.3e-206 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JPCLEFIL_00505 3.5e-137 yvpB NU protein conserved in bacteria
JPCLEFIL_00506 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
JPCLEFIL_00507 2.7e-112 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
JPCLEFIL_00508 6.4e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JPCLEFIL_00509 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JPCLEFIL_00510 1.5e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JPCLEFIL_00511 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JPCLEFIL_00512 2.3e-133 yvoA K transcriptional
JPCLEFIL_00513 4.4e-103 yxaF K Transcriptional regulator
JPCLEFIL_00514 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
JPCLEFIL_00515 1.5e-40 yvlD S Membrane
JPCLEFIL_00516 9.6e-26 pspB KT PspC domain
JPCLEFIL_00517 1.2e-165 yvlB S Putative adhesin
JPCLEFIL_00518 6.1e-49 yvlA
JPCLEFIL_00519 2.2e-32 yvkN
JPCLEFIL_00520 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JPCLEFIL_00521 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JPCLEFIL_00522 7.6e-33 csbA S protein conserved in bacteria
JPCLEFIL_00523 0.0 yvkC 2.7.9.2 GT Phosphotransferase
JPCLEFIL_00524 2e-109 yvkB K Transcriptional regulator
JPCLEFIL_00525 9.6e-226 yvkA EGP Major facilitator Superfamily
JPCLEFIL_00526 1.2e-64 L COG2801 Transposase and inactivated derivatives
JPCLEFIL_00527 2.2e-08 L Transposase, Mutator family
JPCLEFIL_00528 2.1e-17 L Transposase, Mutator family
JPCLEFIL_00529 7.9e-28 L Transposase, Mutator family
JPCLEFIL_00530 2.6e-14 bacT Q Thioesterase domain
JPCLEFIL_00531 1.1e-174 S Psort location CytoplasmicMembrane, score
JPCLEFIL_00532 1.1e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JPCLEFIL_00533 1.5e-55 swrA S Swarming motility protein
JPCLEFIL_00534 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
JPCLEFIL_00535 1.6e-223 ywoF P Right handed beta helix region
JPCLEFIL_00536 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JPCLEFIL_00537 2.3e-122 ftsE D cell division ATP-binding protein FtsE
JPCLEFIL_00538 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
JPCLEFIL_00539 3e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
JPCLEFIL_00540 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JPCLEFIL_00541 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JPCLEFIL_00542 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JPCLEFIL_00543 6.8e-68
JPCLEFIL_00544 4.5e-10 fliT S bacterial-type flagellum organization
JPCLEFIL_00545 3e-66 fliS N flagellar protein FliS
JPCLEFIL_00546 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JPCLEFIL_00547 1.9e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JPCLEFIL_00548 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JPCLEFIL_00549 3.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JPCLEFIL_00550 1.4e-80 yviE
JPCLEFIL_00551 2.3e-162 flgL N Belongs to the bacterial flagellin family
JPCLEFIL_00552 1.4e-273 flgK N flagellar hook-associated protein
JPCLEFIL_00553 8.9e-81 flgN NOU FlgN protein
JPCLEFIL_00554 1.8e-38 flgM KNU Negative regulator of flagellin synthesis
JPCLEFIL_00555 1.2e-73 yvyF S flagellar protein
JPCLEFIL_00556 6.6e-108 comFC S Phosphoribosyl transferase domain
JPCLEFIL_00557 1.1e-41 comFB S Late competence development protein ComFB
JPCLEFIL_00558 1.1e-253 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JPCLEFIL_00559 1.4e-158 degV S protein conserved in bacteria
JPCLEFIL_00560 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPCLEFIL_00561 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
JPCLEFIL_00562 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
JPCLEFIL_00563 6e-166 yvhJ K Transcriptional regulator
JPCLEFIL_00564 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
JPCLEFIL_00565 5e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
JPCLEFIL_00566 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
JPCLEFIL_00567 1.9e-113 tuaF M protein involved in exopolysaccharide biosynthesis
JPCLEFIL_00568 5.7e-253 tuaE M Teichuronic acid biosynthesis protein
JPCLEFIL_00569 3.4e-247 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JPCLEFIL_00570 2.6e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
JPCLEFIL_00571 1.3e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JPCLEFIL_00572 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JPCLEFIL_00573 2.7e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JPCLEFIL_00574 6.7e-306 lytB 3.5.1.28 D Stage II sporulation protein
JPCLEFIL_00575 5.9e-30
JPCLEFIL_00576 3.4e-137 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
JPCLEFIL_00577 2.7e-184 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JPCLEFIL_00578 3.7e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JPCLEFIL_00579 1.6e-179 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JPCLEFIL_00580 2.2e-135 tagG GM Transport permease protein
JPCLEFIL_00581 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JPCLEFIL_00582 2.4e-244 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
JPCLEFIL_00583 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
JPCLEFIL_00584 3.8e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JPCLEFIL_00585 2.7e-208 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JPCLEFIL_00586 2.6e-129 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JPCLEFIL_00587 3.8e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
JPCLEFIL_00588 5.7e-264 gerBA EG Spore germination protein
JPCLEFIL_00589 7.8e-197 gerBB E Spore germination protein
JPCLEFIL_00590 2.2e-210 gerAC S Spore germination protein
JPCLEFIL_00591 4.4e-266 GT2,GT4 J Glycosyl transferase family 2
JPCLEFIL_00592 4.9e-249 ywtG EGP Major facilitator Superfamily
JPCLEFIL_00593 8e-177 ywtF K Transcriptional regulator
JPCLEFIL_00594 2.7e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
JPCLEFIL_00595 5e-35 yttA 2.7.13.3 S Pfam Transposase IS66
JPCLEFIL_00596 1.9e-236 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JPCLEFIL_00597 1.3e-20 ywtC
JPCLEFIL_00598 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
JPCLEFIL_00599 2.3e-70 pgsC S biosynthesis protein
JPCLEFIL_00600 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
JPCLEFIL_00601 4.5e-184 gerKA EG Spore germination protein
JPCLEFIL_00602 3.1e-190 gerKB E Spore germination protein
JPCLEFIL_00603 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
JPCLEFIL_00604 2.1e-177 rbsR K transcriptional
JPCLEFIL_00605 4.8e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JPCLEFIL_00606 1.2e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JPCLEFIL_00607 7.1e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
JPCLEFIL_00608 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
JPCLEFIL_00609 3.7e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
JPCLEFIL_00610 5.8e-89 batE T Sh3 type 3 domain protein
JPCLEFIL_00611 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
JPCLEFIL_00612 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
JPCLEFIL_00613 6.8e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JPCLEFIL_00614 2.6e-166 alsR K LysR substrate binding domain
JPCLEFIL_00616 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JPCLEFIL_00617 7.5e-126 ywrJ
JPCLEFIL_00618 2.8e-128 cotB
JPCLEFIL_00619 4.6e-210 cotH M Spore Coat
JPCLEFIL_00620 1.3e-09
JPCLEFIL_00621 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JPCLEFIL_00623 7.7e-286 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JPCLEFIL_00624 2.5e-83 ywrC K Transcriptional regulator
JPCLEFIL_00625 9.5e-101 ywrB P Chromate transporter
JPCLEFIL_00626 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
JPCLEFIL_00627 1.8e-133 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
JPCLEFIL_00628 1.7e-90
JPCLEFIL_00629 8.4e-16 S SMI1 / KNR4 family
JPCLEFIL_00630 8.7e-67 S SMI1 / KNR4 family (SUKH-1)
JPCLEFIL_00631 7.1e-239 ywqJ S Pre-toxin TG
JPCLEFIL_00632 7.3e-37 ywqI S Family of unknown function (DUF5344)
JPCLEFIL_00633 1.4e-21 S Domain of unknown function (DUF5082)
JPCLEFIL_00635 1.1e-147 ywqG S Domain of unknown function (DUF1963)
JPCLEFIL_00636 1.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JPCLEFIL_00637 2.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
JPCLEFIL_00638 1.6e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
JPCLEFIL_00639 1.8e-109 ywqC M biosynthesis protein
JPCLEFIL_00640 1.3e-14
JPCLEFIL_00641 1.6e-307 ywqB S SWIM zinc finger
JPCLEFIL_00642 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JPCLEFIL_00643 2.2e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
JPCLEFIL_00644 7.5e-138 glcR K DeoR C terminal sensor domain
JPCLEFIL_00645 3.7e-57 ssbB L Single-stranded DNA-binding protein
JPCLEFIL_00646 4e-62 ywpG
JPCLEFIL_00647 2.5e-68 ywpF S YwpF-like protein
JPCLEFIL_00648 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JPCLEFIL_00649 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JPCLEFIL_00650 5.2e-198 S aspartate phosphatase
JPCLEFIL_00651 5.3e-142 flhP N flagellar basal body
JPCLEFIL_00652 2.5e-128 flhO N flagellar basal body
JPCLEFIL_00653 2.7e-180 mbl D Rod shape-determining protein
JPCLEFIL_00654 1.8e-44 spoIIID K Stage III sporulation protein D
JPCLEFIL_00655 2.5e-71 ywoH K transcriptional
JPCLEFIL_00656 2.4e-212 ywoG EGP Major facilitator Superfamily
JPCLEFIL_00657 4.6e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
JPCLEFIL_00658 7.5e-242 ywoD EGP Major facilitator superfamily
JPCLEFIL_00659 4.8e-102 phzA Q Isochorismatase family
JPCLEFIL_00660 2.5e-228 amt P Ammonium transporter
JPCLEFIL_00661 2e-58 nrgB K Belongs to the P(II) protein family
JPCLEFIL_00662 3.9e-207 ftsW D Belongs to the SEDS family
JPCLEFIL_00663 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
JPCLEFIL_00664 5.6e-71 ywnJ S VanZ like family
JPCLEFIL_00665 1.4e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
JPCLEFIL_00666 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
JPCLEFIL_00667 1.2e-10 ywnC S Family of unknown function (DUF5362)
JPCLEFIL_00668 1.2e-68 ywnF S Family of unknown function (DUF5392)
JPCLEFIL_00669 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JPCLEFIL_00670 4.5e-51 ywnC S Family of unknown function (DUF5362)
JPCLEFIL_00671 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
JPCLEFIL_00672 6.1e-67 ywnA K Transcriptional regulator
JPCLEFIL_00673 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JPCLEFIL_00674 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JPCLEFIL_00675 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JPCLEFIL_00676 1.4e-10 csbD K CsbD-like
JPCLEFIL_00677 2.3e-81 ywmF S Peptidase M50
JPCLEFIL_00678 2.8e-93 S response regulator aspartate phosphatase
JPCLEFIL_00679 5.9e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JPCLEFIL_00680 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JPCLEFIL_00682 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
JPCLEFIL_00683 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
JPCLEFIL_00684 1.5e-178 spoIID D Stage II sporulation protein D
JPCLEFIL_00685 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JPCLEFIL_00686 2.2e-134 ywmB S TATA-box binding
JPCLEFIL_00687 4.8e-32 ywzB S membrane
JPCLEFIL_00688 7.3e-88 ywmA
JPCLEFIL_00689 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JPCLEFIL_00690 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JPCLEFIL_00691 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JPCLEFIL_00692 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JPCLEFIL_00693 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JPCLEFIL_00694 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JPCLEFIL_00695 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JPCLEFIL_00696 7.1e-130 atpB C it plays a direct role in the translocation of protons across the membrane
JPCLEFIL_00697 2.1e-61 atpI S ATP synthase
JPCLEFIL_00698 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JPCLEFIL_00699 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JPCLEFIL_00700 1.7e-96 ywlG S Belongs to the UPF0340 family
JPCLEFIL_00701 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
JPCLEFIL_00702 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JPCLEFIL_00703 1.3e-83 mntP P Probably functions as a manganese efflux pump
JPCLEFIL_00704 3.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JPCLEFIL_00705 1.1e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
JPCLEFIL_00706 8.9e-119 spoIIR S stage II sporulation protein R
JPCLEFIL_00707 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
JPCLEFIL_00709 4.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JPCLEFIL_00710 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JPCLEFIL_00711 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JPCLEFIL_00712 2.2e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
JPCLEFIL_00713 6.8e-157 ywkB S Membrane transport protein
JPCLEFIL_00714 0.0 sfcA 1.1.1.38 C malic enzyme
JPCLEFIL_00715 1.7e-102 tdk 2.7.1.21 F thymidine kinase
JPCLEFIL_00716 1.1e-32 rpmE J Binds the 23S rRNA
JPCLEFIL_00717 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JPCLEFIL_00718 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
JPCLEFIL_00719 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JPCLEFIL_00720 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JPCLEFIL_00721 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
JPCLEFIL_00722 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
JPCLEFIL_00723 4.2e-92 ywjG S Domain of unknown function (DUF2529)
JPCLEFIL_00724 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JPCLEFIL_00725 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JPCLEFIL_00726 0.0 fadF C COG0247 Fe-S oxidoreductase
JPCLEFIL_00727 2.3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
JPCLEFIL_00728 7.5e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
JPCLEFIL_00729 4.2e-43 ywjC
JPCLEFIL_00730 0.0 ywjA V ABC transporter
JPCLEFIL_00731 1e-295 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JPCLEFIL_00732 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JPCLEFIL_00733 7.2e-121 narI 1.7.5.1 C nitrate reductase, gamma
JPCLEFIL_00734 6.9e-93 narJ 1.7.5.1 C nitrate reductase
JPCLEFIL_00735 6.9e-294 narH 1.7.5.1 C Nitrate reductase, beta
JPCLEFIL_00736 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JPCLEFIL_00737 1.7e-84 arfM T cyclic nucleotide binding
JPCLEFIL_00738 2.8e-139 ywiC S YwiC-like protein
JPCLEFIL_00739 5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
JPCLEFIL_00740 5.4e-212 narK P COG2223 Nitrate nitrite transporter
JPCLEFIL_00741 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JPCLEFIL_00742 2.9e-43 ywiB S protein conserved in bacteria
JPCLEFIL_00743 3.4e-78 S aspartate phosphatase
JPCLEFIL_00745 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
JPCLEFIL_00746 2e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JPCLEFIL_00747 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPCLEFIL_00748 1.6e-81
JPCLEFIL_00749 2.9e-93 ywhD S YwhD family
JPCLEFIL_00750 1.2e-117 ywhC S Peptidase family M50
JPCLEFIL_00751 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
JPCLEFIL_00752 4.9e-67 ywhA K Transcriptional regulator
JPCLEFIL_00753 1.9e-245 yhdG_1 E C-terminus of AA_permease
JPCLEFIL_00754 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
JPCLEFIL_00755 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
JPCLEFIL_00756 6.9e-36 ywzC S Belongs to the UPF0741 family
JPCLEFIL_00757 6.6e-110 rsfA_1
JPCLEFIL_00758 9.7e-52 padR K PadR family transcriptional regulator
JPCLEFIL_00759 4.5e-92 S membrane
JPCLEFIL_00760 2.1e-40 V ABC transporter, ATP-binding protein
JPCLEFIL_00761 2.8e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
JPCLEFIL_00762 6e-163 cysL K Transcriptional regulator
JPCLEFIL_00763 6.2e-158 MA20_14895 S Conserved hypothetical protein 698
JPCLEFIL_00764 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
JPCLEFIL_00765 3.3e-146 ywfI C May function as heme-dependent peroxidase
JPCLEFIL_00766 1.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
JPCLEFIL_00767 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
JPCLEFIL_00768 1e-207 bacE EGP Major facilitator Superfamily
JPCLEFIL_00769 2.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
JPCLEFIL_00770 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_00771 7.6e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
JPCLEFIL_00772 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
JPCLEFIL_00773 3.5e-222 ywfA EGP Major facilitator Superfamily
JPCLEFIL_00774 1.1e-204 tcaB EGP Major facilitator Superfamily
JPCLEFIL_00775 7e-259 lysP E amino acid
JPCLEFIL_00776 0.0 rocB E arginine degradation protein
JPCLEFIL_00777 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JPCLEFIL_00778 3.6e-246 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JPCLEFIL_00779 1.9e-59
JPCLEFIL_00780 3e-86 spsL 5.1.3.13 M Spore Coat
JPCLEFIL_00781 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JPCLEFIL_00782 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JPCLEFIL_00783 1.3e-136 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JPCLEFIL_00784 1.1e-178 spsG M Spore Coat
JPCLEFIL_00785 2.6e-132 spsF M Spore Coat
JPCLEFIL_00786 1.4e-214 spsE 2.5.1.56 M acid synthase
JPCLEFIL_00787 1.2e-155 spsD 2.3.1.210 K Spore Coat
JPCLEFIL_00788 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
JPCLEFIL_00789 3.5e-274 spsB M Capsule polysaccharide biosynthesis protein
JPCLEFIL_00790 1.7e-142 spsA M Spore Coat
JPCLEFIL_00791 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
JPCLEFIL_00792 4.2e-46 ywdK S small membrane protein
JPCLEFIL_00793 1.2e-228 ywdJ F Xanthine uracil
JPCLEFIL_00794 4.7e-41 ywdI S Family of unknown function (DUF5327)
JPCLEFIL_00795 7.1e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JPCLEFIL_00796 8e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
JPCLEFIL_00798 5.8e-88 ywdD
JPCLEFIL_00799 6.3e-57 pex K Transcriptional regulator PadR-like family
JPCLEFIL_00800 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JPCLEFIL_00801 7.4e-20 ywdA
JPCLEFIL_00802 4.6e-282 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
JPCLEFIL_00803 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JPCLEFIL_00804 2.8e-151 sacT K transcriptional antiterminator
JPCLEFIL_00806 0.0 vpr O Belongs to the peptidase S8 family
JPCLEFIL_00807 1.3e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPCLEFIL_00808 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
JPCLEFIL_00809 2.8e-208 rodA D Belongs to the SEDS family
JPCLEFIL_00810 4.8e-76 ysnE K acetyltransferase
JPCLEFIL_00811 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
JPCLEFIL_00812 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JPCLEFIL_00813 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JPCLEFIL_00814 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JPCLEFIL_00815 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
JPCLEFIL_00816 8.4e-27 ywzA S membrane
JPCLEFIL_00817 1.1e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JPCLEFIL_00818 1.5e-60 gtcA S GtrA-like protein
JPCLEFIL_00819 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
JPCLEFIL_00821 1.2e-128 H Methionine biosynthesis protein MetW
JPCLEFIL_00822 1.2e-131 S Streptomycin biosynthesis protein StrF
JPCLEFIL_00823 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JPCLEFIL_00824 1.1e-242 ywbN P Dyp-type peroxidase family protein
JPCLEFIL_00825 3.3e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JPCLEFIL_00826 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JPCLEFIL_00827 8.2e-152 ywbI K Transcriptional regulator
JPCLEFIL_00828 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
JPCLEFIL_00829 1.3e-109 ywbG M effector of murein hydrolase
JPCLEFIL_00830 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
JPCLEFIL_00831 9e-136 mta K transcriptional
JPCLEFIL_00832 1e-223 ywbD 2.1.1.191 J Methyltransferase
JPCLEFIL_00833 7.6e-67 ywbC 4.4.1.5 E glyoxalase
JPCLEFIL_00834 5.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JPCLEFIL_00835 4.3e-258 epr 3.4.21.62 O Belongs to the peptidase S8 family
JPCLEFIL_00836 1.6e-160 gspA M General stress
JPCLEFIL_00837 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
JPCLEFIL_00838 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
JPCLEFIL_00839 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
JPCLEFIL_00840 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_00841 4.8e-229 dltB M membrane protein involved in D-alanine export
JPCLEFIL_00842 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_00843 1.2e-227 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JPCLEFIL_00844 7.1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JPCLEFIL_00845 1e-251 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JPCLEFIL_00846 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
JPCLEFIL_00847 7.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JPCLEFIL_00848 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
JPCLEFIL_00849 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
JPCLEFIL_00850 7.8e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JPCLEFIL_00851 6.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_00852 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_00853 1.5e-166 cbrA3 P Periplasmic binding protein
JPCLEFIL_00854 1.7e-57 arsR K transcriptional
JPCLEFIL_00855 6.5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JPCLEFIL_00856 1.3e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
JPCLEFIL_00857 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
JPCLEFIL_00858 4.1e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JPCLEFIL_00859 2.8e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPCLEFIL_00860 8.2e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
JPCLEFIL_00861 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
JPCLEFIL_00862 1.3e-209 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
JPCLEFIL_00863 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JPCLEFIL_00864 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
JPCLEFIL_00865 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
JPCLEFIL_00866 4.7e-154 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JPCLEFIL_00867 1.3e-291 cydD V ATP-binding protein
JPCLEFIL_00868 0.0 cydD V ATP-binding
JPCLEFIL_00869 9.7e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
JPCLEFIL_00870 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
JPCLEFIL_00871 1.3e-214 cimH C COG3493 Na citrate symporter
JPCLEFIL_00872 4.3e-155 yxkH G Polysaccharide deacetylase
JPCLEFIL_00873 1.3e-204 msmK P Belongs to the ABC transporter superfamily
JPCLEFIL_00874 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
JPCLEFIL_00875 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JPCLEFIL_00876 3.8e-87 yxkC S Domain of unknown function (DUF4352)
JPCLEFIL_00877 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JPCLEFIL_00878 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JPCLEFIL_00881 2e-85 yxjI S LURP-one-related
JPCLEFIL_00882 4.1e-217 yxjG 2.1.1.14 E Methionine synthase
JPCLEFIL_00883 2.6e-155 rlmA 2.1.1.187 Q Methyltransferase domain
JPCLEFIL_00884 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JPCLEFIL_00885 1.8e-71 T Domain of unknown function (DUF4163)
JPCLEFIL_00886 4.3e-49 yxiS
JPCLEFIL_00888 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
JPCLEFIL_00889 1.4e-221 citH C Citrate transporter
JPCLEFIL_00890 4.9e-139 exoK GH16 M licheninase activity
JPCLEFIL_00891 4.1e-105 licT K transcriptional antiterminator
JPCLEFIL_00892 4.1e-21 licT K transcriptional antiterminator
JPCLEFIL_00893 1.3e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
JPCLEFIL_00894 1.1e-259 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
JPCLEFIL_00897 1.2e-61 S SMI1-KNR4 cell-wall
JPCLEFIL_00898 7e-49 yxiI S Protein of unknown function (DUF2716)
JPCLEFIL_00899 6.6e-20
JPCLEFIL_00900 8.3e-13 S YxiJ-like protein
JPCLEFIL_00901 5.2e-108
JPCLEFIL_00902 2.3e-78
JPCLEFIL_00905 1e-06
JPCLEFIL_00906 4.7e-36
JPCLEFIL_00908 2.5e-52
JPCLEFIL_00909 0.0 wapA M COG3209 Rhs family protein
JPCLEFIL_00910 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
JPCLEFIL_00911 3.9e-146 yxxF EG EamA-like transporter family
JPCLEFIL_00912 1.1e-72 yxiE T Belongs to the universal stress protein A family
JPCLEFIL_00913 0.0 L HKD family nuclease
JPCLEFIL_00914 5.5e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JPCLEFIL_00915 7.6e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JPCLEFIL_00916 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
JPCLEFIL_00917 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
JPCLEFIL_00918 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JPCLEFIL_00919 1.4e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
JPCLEFIL_00920 4.7e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
JPCLEFIL_00921 4.4e-253 lysP E amino acid
JPCLEFIL_00922 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
JPCLEFIL_00923 6.8e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JPCLEFIL_00924 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JPCLEFIL_00925 5.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JPCLEFIL_00926 2.6e-149 yidA S hydrolases of the HAD superfamily
JPCLEFIL_00930 8.4e-23 yxeD
JPCLEFIL_00931 1.3e-34
JPCLEFIL_00932 4.1e-178 fhuD P Periplasmic binding protein
JPCLEFIL_00933 1.3e-57 yxeA S Protein of unknown function (DUF1093)
JPCLEFIL_00934 0.0 yxdM V ABC transporter (permease)
JPCLEFIL_00935 3.6e-140 yxdL V ABC transporter, ATP-binding protein
JPCLEFIL_00936 2.5e-175 T PhoQ Sensor
JPCLEFIL_00937 3.5e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_00939 4.7e-157 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
JPCLEFIL_00940 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
JPCLEFIL_00941 3.3e-166 iolH G Xylose isomerase-like TIM barrel
JPCLEFIL_00942 4.4e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
JPCLEFIL_00943 3.3e-231 iolF EGP Major facilitator Superfamily
JPCLEFIL_00944 8.8e-175 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
JPCLEFIL_00945 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
JPCLEFIL_00946 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
JPCLEFIL_00947 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
JPCLEFIL_00948 4.8e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JPCLEFIL_00949 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
JPCLEFIL_00950 4.6e-174 iolS C Aldo keto reductase
JPCLEFIL_00951 4.3e-245 csbC EGP Major facilitator Superfamily
JPCLEFIL_00952 0.0 htpG O Molecular chaperone. Has ATPase activity
JPCLEFIL_00954 8.2e-151 IQ Enoyl-(Acyl carrier protein) reductase
JPCLEFIL_00955 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPCLEFIL_00956 4.5e-200 desK 2.7.13.3 T Histidine kinase
JPCLEFIL_00957 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JPCLEFIL_00958 6.2e-213 yxbF K Bacterial regulatory proteins, tetR family
JPCLEFIL_00959 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JPCLEFIL_00960 2.8e-142 S PQQ-like domain
JPCLEFIL_00961 2.3e-64 S Family of unknown function (DUF5391)
JPCLEFIL_00962 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
JPCLEFIL_00963 3.2e-201 EGP Major facilitator Superfamily
JPCLEFIL_00964 7.6e-74 yxaI S membrane protein domain
JPCLEFIL_00965 1.4e-124 E Ring-cleavage extradiol dioxygenase
JPCLEFIL_00966 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
JPCLEFIL_00967 6.6e-287 ahpF O Alkyl hydroperoxide reductase
JPCLEFIL_00968 9.3e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
JPCLEFIL_00969 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
JPCLEFIL_00970 1.4e-83 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
JPCLEFIL_00971 1.4e-153 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
JPCLEFIL_00972 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
JPCLEFIL_00973 1.4e-86 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
JPCLEFIL_00974 5.3e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JPCLEFIL_00975 6.9e-176 S Fusaric acid resistance protein-like
JPCLEFIL_00976 2.7e-17
JPCLEFIL_00977 3.6e-20
JPCLEFIL_00978 4.1e-223
JPCLEFIL_00979 2.4e-108 mjecl24 D Involved in chromosome partitioning
JPCLEFIL_00980 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JPCLEFIL_00981 3.6e-08 S YyzF-like protein
JPCLEFIL_00984 5.1e-215 yycP
JPCLEFIL_00985 1e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JPCLEFIL_00986 1.5e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
JPCLEFIL_00987 3.7e-87 yycN 2.3.1.128 K Acetyltransferase
JPCLEFIL_00989 2.2e-199 S Histidine kinase
JPCLEFIL_00990 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
JPCLEFIL_00991 3.8e-257 rocE E amino acid
JPCLEFIL_00992 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
JPCLEFIL_00993 7.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
JPCLEFIL_00994 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
JPCLEFIL_00995 1.7e-304 S ABC transporter
JPCLEFIL_00996 3.4e-198 S Major Facilitator Superfamily
JPCLEFIL_00997 2.1e-257
JPCLEFIL_00998 2.7e-188 2.7.7.73, 2.7.7.80 H ThiF family
JPCLEFIL_00999 1.5e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
JPCLEFIL_01000 2.8e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_01001 1.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JPCLEFIL_01002 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
JPCLEFIL_01003 1.1e-150 yycI S protein conserved in bacteria
JPCLEFIL_01004 2.5e-261 yycH S protein conserved in bacteria
JPCLEFIL_01005 0.0 vicK 2.7.13.3 T Histidine kinase
JPCLEFIL_01006 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_01011 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JPCLEFIL_01012 4.2e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JPCLEFIL_01013 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JPCLEFIL_01014 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
JPCLEFIL_01016 4.6e-17 yycC K YycC-like protein
JPCLEFIL_01017 2.2e-235 M Glycosyltransferase Family 4
JPCLEFIL_01018 2.4e-203 S Ecdysteroid kinase
JPCLEFIL_01019 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
JPCLEFIL_01020 2.1e-241 M Glycosyltransferase Family 4
JPCLEFIL_01021 1.1e-121 S GlcNAc-PI de-N-acetylase
JPCLEFIL_01022 6.4e-122 KLT COG0515 Serine threonine protein kinase
JPCLEFIL_01023 4.9e-73 rplI J binds to the 23S rRNA
JPCLEFIL_01024 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JPCLEFIL_01025 2.4e-159 yybS S membrane
JPCLEFIL_01027 2.7e-83 cotF M Spore coat protein
JPCLEFIL_01028 8.2e-66 ydeP3 K Transcriptional regulator
JPCLEFIL_01029 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
JPCLEFIL_01030 1e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JPCLEFIL_01031 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
JPCLEFIL_01032 2.1e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
JPCLEFIL_01033 2.2e-114 K FCD domain
JPCLEFIL_01034 6.3e-77 dinB S PFAM DinB family protein
JPCLEFIL_01035 3.2e-159 G Major Facilitator Superfamily
JPCLEFIL_01036 2.2e-55 ypaA S Protein of unknown function (DUF1304)
JPCLEFIL_01037 2.1e-114 drgA C nitroreductase
JPCLEFIL_01038 4.1e-69 ydgJ K Winged helix DNA-binding domain
JPCLEFIL_01039 8.7e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JPCLEFIL_01040 1.6e-76 yybA 2.3.1.57 K transcriptional
JPCLEFIL_01041 8.9e-61 lysR K LysR substrate binding domain
JPCLEFIL_01042 1.9e-92
JPCLEFIL_01043 6.4e-162 eaeH M Domain of Unknown Function (DUF1259)
JPCLEFIL_01044 1.7e-64 4.1.1.44 S Carboxymuconolactone decarboxylase family
JPCLEFIL_01045 2.5e-161 K Transcriptional regulator
JPCLEFIL_01046 3.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JPCLEFIL_01047 1.6e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JPCLEFIL_01048 1.6e-131 ydfC EG EamA-like transporter family
JPCLEFIL_01049 4.3e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JPCLEFIL_01050 3.3e-78 K Transcriptional regulator
JPCLEFIL_01051 7.6e-14 yvaO K Transcriptional
JPCLEFIL_01052 2.7e-40 qacC U Small Multidrug Resistance protein
JPCLEFIL_01053 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
JPCLEFIL_01054 7.3e-161 yyaK S CAAX protease self-immunity
JPCLEFIL_01055 5.8e-247 ydjK G Sugar (and other) transporter
JPCLEFIL_01056 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JPCLEFIL_01057 1.2e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
JPCLEFIL_01058 7.8e-140 xth 3.1.11.2 L exodeoxyribonuclease III
JPCLEFIL_01059 8.7e-96 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JPCLEFIL_01060 6.3e-105 adaA 3.2.2.21 K Transcriptional regulator
JPCLEFIL_01061 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JPCLEFIL_01062 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JPCLEFIL_01063 3.6e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
JPCLEFIL_01064 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JPCLEFIL_01065 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JPCLEFIL_01066 6.6e-33 yyzM S protein conserved in bacteria
JPCLEFIL_01067 2.4e-176 yyaD S Membrane
JPCLEFIL_01068 1.4e-55 4.2.1.103 K FR47-like protein
JPCLEFIL_01069 6.2e-111 yyaC S Sporulation protein YyaC
JPCLEFIL_01070 7.9e-149 spo0J K Belongs to the ParB family
JPCLEFIL_01071 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
JPCLEFIL_01072 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
JPCLEFIL_01073 7.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
JPCLEFIL_01074 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JPCLEFIL_01075 2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JPCLEFIL_01076 1.3e-108 jag S single-stranded nucleic acid binding R3H
JPCLEFIL_01077 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JPCLEFIL_01078 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JPCLEFIL_01079 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JPCLEFIL_01080 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JPCLEFIL_01081 2.4e-33 yaaA S S4 domain
JPCLEFIL_01082 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JPCLEFIL_01083 8.1e-38 yaaB S Domain of unknown function (DUF370)
JPCLEFIL_01084 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JPCLEFIL_01085 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JPCLEFIL_01086 1.1e-164 ygxA S Nucleotidyltransferase-like
JPCLEFIL_01087 1.5e-56 ygzB S UPF0295 protein
JPCLEFIL_01088 1.8e-80 perR P Belongs to the Fur family
JPCLEFIL_01089 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
JPCLEFIL_01090 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JPCLEFIL_01091 2.7e-178 ygaE S Membrane
JPCLEFIL_01092 1e-299 ygaD V ABC transporter
JPCLEFIL_01093 2.2e-104 ygaC J Belongs to the UPF0374 family
JPCLEFIL_01094 1.5e-37 ygaB S YgaB-like protein
JPCLEFIL_01096 3.7e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_01097 1.3e-34 yfhS
JPCLEFIL_01098 4.8e-207 mutY L A G-specific
JPCLEFIL_01099 1e-184 yfhP S membrane-bound metal-dependent
JPCLEFIL_01100 0.0 yfhO S Bacterial membrane protein YfhO
JPCLEFIL_01101 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JPCLEFIL_01102 8.2e-170 yfhM S Alpha/beta hydrolase family
JPCLEFIL_01103 9.7e-34 yfhL S SdpI/YhfL protein family
JPCLEFIL_01104 8.5e-93 batE T Bacterial SH3 domain homologues
JPCLEFIL_01105 2.2e-44 yfhJ S WVELL protein
JPCLEFIL_01106 5.3e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
JPCLEFIL_01108 4.2e-204 yfhI EGP Major facilitator Superfamily
JPCLEFIL_01109 2.5e-52 yfhH S Protein of unknown function (DUF1811)
JPCLEFIL_01110 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
JPCLEFIL_01111 4.9e-165 yfhF S nucleoside-diphosphate sugar epimerase
JPCLEFIL_01113 2.1e-25 yfhD S YfhD-like protein
JPCLEFIL_01114 1.7e-105 yfhC C nitroreductase
JPCLEFIL_01115 7.2e-161 yfhB 5.3.3.17 S PhzF family
JPCLEFIL_01116 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JPCLEFIL_01117 6.2e-82 yfiV K transcriptional
JPCLEFIL_01118 3.3e-289 yfiU EGP Major facilitator Superfamily
JPCLEFIL_01119 9.7e-55 yfiT S Belongs to the metal hydrolase YfiT family
JPCLEFIL_01120 1.6e-18 yfiT S Belongs to the metal hydrolase YfiT family
JPCLEFIL_01121 4.5e-45 yrdF K ribonuclease inhibitor
JPCLEFIL_01122 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
JPCLEFIL_01123 3.2e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JPCLEFIL_01124 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
JPCLEFIL_01125 6.6e-96 padR K transcriptional
JPCLEFIL_01126 6.7e-165 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JPCLEFIL_01127 2.5e-158 yfiE 1.13.11.2 S glyoxalase
JPCLEFIL_01128 9.2e-63 mhqP S DoxX
JPCLEFIL_01129 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
JPCLEFIL_01130 2.4e-309 yfiB3 V ABC transporter
JPCLEFIL_01131 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
JPCLEFIL_01132 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JPCLEFIL_01133 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
JPCLEFIL_01134 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JPCLEFIL_01135 4.2e-15 sspH S Belongs to the SspH family
JPCLEFIL_01136 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
JPCLEFIL_01137 2.3e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JPCLEFIL_01138 1.4e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JPCLEFIL_01139 2e-186 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JPCLEFIL_01140 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JPCLEFIL_01141 5.7e-88 yfjM S Psort location Cytoplasmic, score
JPCLEFIL_01142 1.8e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JPCLEFIL_01143 8.7e-44 S YfzA-like protein
JPCLEFIL_01144 1.3e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JPCLEFIL_01145 7.5e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JPCLEFIL_01146 8.5e-184 corA P Mediates influx of magnesium ions
JPCLEFIL_01147 3.3e-30
JPCLEFIL_01148 3e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
JPCLEFIL_01149 9e-155 pdaA G deacetylase
JPCLEFIL_01150 4.9e-27 yfjT
JPCLEFIL_01151 7.3e-219 yfkA S YfkB-like domain
JPCLEFIL_01152 6.8e-145 yfkC M Mechanosensitive ion channel
JPCLEFIL_01153 1.6e-143 yfkD S YfkD-like protein
JPCLEFIL_01154 2.2e-185 cax P COG0387 Ca2 H antiporter
JPCLEFIL_01155 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
JPCLEFIL_01156 2.5e-07
JPCLEFIL_01157 7.6e-144 yihY S Belongs to the UPF0761 family
JPCLEFIL_01158 1e-51 yfkI S gas vesicle protein
JPCLEFIL_01159 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JPCLEFIL_01160 2.7e-29 yfkK S Belongs to the UPF0435 family
JPCLEFIL_01161 8.1e-192 ydiM EGP Major facilitator Superfamily
JPCLEFIL_01162 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JPCLEFIL_01163 1.9e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JPCLEFIL_01164 9.8e-186 K helix_turn _helix lactose operon repressor
JPCLEFIL_01165 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
JPCLEFIL_01166 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
JPCLEFIL_01167 5.5e-198 yibE S YibE/F-like protein
JPCLEFIL_01168 1e-123 yibF S YibE/F-like protein
JPCLEFIL_01169 1.2e-123 yfkO C nitroreductase
JPCLEFIL_01170 2e-129 treR K transcriptional
JPCLEFIL_01171 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JPCLEFIL_01172 1.6e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JPCLEFIL_01173 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
JPCLEFIL_01174 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
JPCLEFIL_01175 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
JPCLEFIL_01176 2.3e-63 yhdN S Domain of unknown function (DUF1992)
JPCLEFIL_01177 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JPCLEFIL_01178 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
JPCLEFIL_01179 3.3e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
JPCLEFIL_01180 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
JPCLEFIL_01181 3.1e-50 yflH S Protein of unknown function (DUF3243)
JPCLEFIL_01182 7e-19 yflI
JPCLEFIL_01183 1.5e-14 yflJ S Protein of unknown function (DUF2639)
JPCLEFIL_01184 1.3e-122 yflK S protein conserved in bacteria
JPCLEFIL_01185 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JPCLEFIL_01186 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JPCLEFIL_01187 4.8e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
JPCLEFIL_01188 1e-224 citM C Citrate transporter
JPCLEFIL_01189 4.6e-177 yflP S Tripartite tricarboxylate transporter family receptor
JPCLEFIL_01190 2.6e-118 citT T response regulator
JPCLEFIL_01191 3.7e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JPCLEFIL_01192 1e-79 srtA 3.4.22.70 M Sortase family
JPCLEFIL_01193 3e-115 M cell wall anchor domain
JPCLEFIL_01194 1.1e-150 M1-574 T Transcriptional regulatory protein, C terminal
JPCLEFIL_01195 0.0 ywpD T PhoQ Sensor
JPCLEFIL_01196 1.8e-77 M1-820 Q Collagen triple helix repeat (20 copies)
JPCLEFIL_01197 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_01198 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_01199 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_01200 4.8e-182 yaaC S YaaC-like Protein
JPCLEFIL_01201 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JPCLEFIL_01202 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JPCLEFIL_01203 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JPCLEFIL_01204 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JPCLEFIL_01205 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JPCLEFIL_01206 1.3e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JPCLEFIL_01207 1.3e-09
JPCLEFIL_01208 1.6e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
JPCLEFIL_01209 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
JPCLEFIL_01210 1.7e-211 yaaH M Glycoside Hydrolase Family
JPCLEFIL_01211 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
JPCLEFIL_01212 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JPCLEFIL_01213 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JPCLEFIL_01214 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JPCLEFIL_01215 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JPCLEFIL_01216 3.6e-32 yaaL S Protein of unknown function (DUF2508)
JPCLEFIL_01217 5.6e-37 bofA S Sigma-K factor-processing regulatory protein BofA
JPCLEFIL_01219 1.3e-07
JPCLEFIL_01222 2e-08
JPCLEFIL_01226 2.7e-107 xkdQ 3.2.1.96 G NLP P60 protein
JPCLEFIL_01227 7.2e-32 xkdR S Protein of unknown function (DUF2577)
JPCLEFIL_01228 4.2e-58 xkdS S Protein of unknown function (DUF2634)
JPCLEFIL_01229 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
JPCLEFIL_01230 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
JPCLEFIL_01231 2.1e-26
JPCLEFIL_01232 6.1e-187
JPCLEFIL_01234 6.5e-30 xkdX
JPCLEFIL_01235 1.8e-136 xepA
JPCLEFIL_01236 8.7e-38 xhlA S Haemolysin XhlA
JPCLEFIL_01237 2.3e-38 xhlB S SPP1 phage holin
JPCLEFIL_01238 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JPCLEFIL_01239 8.7e-23 spoIISB S Stage II sporulation protein SB
JPCLEFIL_01240 1.6e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
JPCLEFIL_01241 5.8e-175 pit P phosphate transporter
JPCLEFIL_01242 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
JPCLEFIL_01243 1.1e-242 steT E amino acid
JPCLEFIL_01244 8.2e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
JPCLEFIL_01245 1.2e-305 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JPCLEFIL_01246 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JPCLEFIL_01248 4.7e-204 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JPCLEFIL_01249 6.3e-277 yubD P Major Facilitator Superfamily
JPCLEFIL_01250 6.5e-156 dppA E D-aminopeptidase
JPCLEFIL_01251 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPCLEFIL_01252 1.1e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPCLEFIL_01253 2.9e-190 dppD P Belongs to the ABC transporter superfamily
JPCLEFIL_01254 0.0 dppE E ABC transporter substrate-binding protein
JPCLEFIL_01255 2.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JPCLEFIL_01256 1.1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JPCLEFIL_01257 1.5e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JPCLEFIL_01258 1.4e-181 ykfD E Belongs to the ABC transporter superfamily
JPCLEFIL_01259 1.9e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
JPCLEFIL_01260 9.4e-158 ykgA E Amidinotransferase
JPCLEFIL_01261 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
JPCLEFIL_01262 3.7e-99 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JPCLEFIL_01263 1.4e-51 ykkC P Multidrug resistance protein
JPCLEFIL_01264 1e-48 ykkD P Multidrug resistance protein
JPCLEFIL_01265 5.6e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
JPCLEFIL_01266 5.1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JPCLEFIL_01267 3.8e-224 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JPCLEFIL_01268 5.3e-69 ohrA O Organic hydroperoxide resistance protein
JPCLEFIL_01269 2.1e-75 ohrR K COG1846 Transcriptional regulators
JPCLEFIL_01270 4.2e-71 ohrB O Organic hydroperoxide resistance protein
JPCLEFIL_01271 3.5e-55 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JPCLEFIL_01273 8.4e-215 M Glycosyl transferase family 2
JPCLEFIL_01274 6.7e-122 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
JPCLEFIL_01275 3e-215 hcaT 1.5.1.2 EGP Major facilitator Superfamily
JPCLEFIL_01276 5.8e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JPCLEFIL_01277 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JPCLEFIL_01278 5e-176 isp O Belongs to the peptidase S8 family
JPCLEFIL_01279 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JPCLEFIL_01280 3.5e-132 ykoC P Cobalt transport protein
JPCLEFIL_01281 5.3e-303 P ABC transporter, ATP-binding protein
JPCLEFIL_01282 2.9e-97 ykoE S ABC-type cobalt transport system, permease component
JPCLEFIL_01283 7.4e-244 ydhD M Glycosyl hydrolase
JPCLEFIL_01285 2.2e-238 mgtE P Acts as a magnesium transporter
JPCLEFIL_01286 5.4e-53 tnrA K transcriptional
JPCLEFIL_01287 1.9e-16
JPCLEFIL_01288 3.1e-26 ykoL
JPCLEFIL_01289 1.1e-80 ykoM K transcriptional
JPCLEFIL_01290 3.7e-99 ykoP G polysaccharide deacetylase
JPCLEFIL_01291 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
JPCLEFIL_01292 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JPCLEFIL_01293 1.7e-99 ykoX S membrane-associated protein
JPCLEFIL_01294 1.5e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
JPCLEFIL_01295 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JPCLEFIL_01296 4.5e-118 rsgI S Anti-sigma factor N-terminus
JPCLEFIL_01297 2.5e-26 sspD S small acid-soluble spore protein
JPCLEFIL_01298 8.6e-125 ykrK S Domain of unknown function (DUF1836)
JPCLEFIL_01299 4.5e-155 htpX O Belongs to the peptidase M48B family
JPCLEFIL_01300 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
JPCLEFIL_01301 7.2e-113 ydfR S Protein of unknown function (DUF421)
JPCLEFIL_01302 8.7e-23 ykzE
JPCLEFIL_01303 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
JPCLEFIL_01304 0.0 kinE 2.7.13.3 T Histidine kinase
JPCLEFIL_01305 1.1e-86 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JPCLEFIL_01307 6.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JPCLEFIL_01308 5.5e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JPCLEFIL_01309 3.8e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JPCLEFIL_01310 4.6e-227 mtnE 2.6.1.83 E Aminotransferase
JPCLEFIL_01311 1.3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
JPCLEFIL_01312 1.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JPCLEFIL_01313 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
JPCLEFIL_01314 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JPCLEFIL_01315 3.4e-10 S Spo0E like sporulation regulatory protein
JPCLEFIL_01316 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
JPCLEFIL_01317 5.5e-77 ykvE K transcriptional
JPCLEFIL_01318 2.7e-127 motB N Flagellar motor protein
JPCLEFIL_01319 3.3e-136 motA N flagellar motor
JPCLEFIL_01320 0.0 clpE O Belongs to the ClpA ClpB family
JPCLEFIL_01321 1.3e-182 ykvI S membrane
JPCLEFIL_01322 5.9e-184
JPCLEFIL_01323 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JPCLEFIL_01324 3.8e-78 queD 4.1.2.50, 4.2.3.12 H synthase
JPCLEFIL_01325 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JPCLEFIL_01326 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JPCLEFIL_01327 3.5e-45 ykvR S Protein of unknown function (DUF3219)
JPCLEFIL_01328 7.8e-25 ykvS S protein conserved in bacteria
JPCLEFIL_01329 3.9e-27
JPCLEFIL_01330 9.1e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
JPCLEFIL_01331 4e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JPCLEFIL_01332 1.7e-87 stoA CO thiol-disulfide
JPCLEFIL_01333 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JPCLEFIL_01334 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JPCLEFIL_01336 9.5e-175 ykvZ 5.1.1.1 K Transcriptional regulator
JPCLEFIL_01337 5.1e-156 glcT K antiterminator
JPCLEFIL_01338 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JPCLEFIL_01339 2.1e-39 ptsH G phosphocarrier protein HPr
JPCLEFIL_01340 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JPCLEFIL_01341 6.1e-38 splA S Transcriptional regulator
JPCLEFIL_01342 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
JPCLEFIL_01343 1.3e-263 mcpC NT chemotaxis protein
JPCLEFIL_01344 4.3e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
JPCLEFIL_01345 1.1e-115 ykwD J protein with SCP PR1 domains
JPCLEFIL_01346 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
JPCLEFIL_01347 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
JPCLEFIL_01348 4.3e-214 patA 2.6.1.1 E Aminotransferase
JPCLEFIL_01349 1.8e-09
JPCLEFIL_01350 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
JPCLEFIL_01351 1.4e-83 ykyB S YkyB-like protein
JPCLEFIL_01352 1.5e-239 ykuC EGP Major facilitator Superfamily
JPCLEFIL_01353 4.6e-88 ykuD S protein conserved in bacteria
JPCLEFIL_01354 3.1e-153 ykuE S Metallophosphoesterase
JPCLEFIL_01355 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_01357 3.3e-233 ykuI T Diguanylate phosphodiesterase
JPCLEFIL_01358 3.9e-37 ykuJ S protein conserved in bacteria
JPCLEFIL_01359 1.4e-92 ykuK S Ribonuclease H-like
JPCLEFIL_01360 2.1e-25 ykzF S Antirepressor AbbA
JPCLEFIL_01361 1e-75 ykuL S CBS domain
JPCLEFIL_01362 1.3e-167 ccpC K Transcriptional regulator
JPCLEFIL_01363 6.7e-89 fld C Flavodoxin
JPCLEFIL_01364 5.7e-166 ykuO
JPCLEFIL_01365 6e-79 fld C Flavodoxin
JPCLEFIL_01366 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JPCLEFIL_01367 9.9e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JPCLEFIL_01368 4.8e-38 ykuS S Belongs to the UPF0180 family
JPCLEFIL_01369 3.7e-140 ykuT M Mechanosensitive ion channel
JPCLEFIL_01370 3.3e-77 ykuV CO thiol-disulfide
JPCLEFIL_01371 4.5e-98 rok K Repressor of ComK
JPCLEFIL_01372 1.1e-160 yknT
JPCLEFIL_01373 2.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
JPCLEFIL_01374 5.5e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JPCLEFIL_01375 6e-241 moeA 2.10.1.1 H molybdopterin
JPCLEFIL_01376 3.2e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
JPCLEFIL_01377 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
JPCLEFIL_01378 1.4e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JPCLEFIL_01379 4.4e-105 yknW S Yip1 domain
JPCLEFIL_01380 6e-168 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JPCLEFIL_01381 2.6e-121 macB V ABC transporter, ATP-binding protein
JPCLEFIL_01382 3e-210 yknZ V ABC transporter (permease)
JPCLEFIL_01383 1.1e-130 fruR K Transcriptional regulator
JPCLEFIL_01384 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
JPCLEFIL_01385 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
JPCLEFIL_01386 3.3e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JPCLEFIL_01387 1.7e-36 ykoA
JPCLEFIL_01388 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JPCLEFIL_01389 9.9e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JPCLEFIL_01390 4.7e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JPCLEFIL_01391 5.5e-12 S Uncharacterized protein YkpC
JPCLEFIL_01392 6.9e-184 mreB D Rod-share determining protein MreBH
JPCLEFIL_01393 1.8e-44 abrB K of stationary sporulation gene expression
JPCLEFIL_01394 1.7e-243 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
JPCLEFIL_01395 1.1e-147 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
JPCLEFIL_01396 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
JPCLEFIL_01397 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JPCLEFIL_01398 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JPCLEFIL_01399 8.2e-31 ykzG S Belongs to the UPF0356 family
JPCLEFIL_01400 7.4e-146 ykrA S hydrolases of the HAD superfamily
JPCLEFIL_01401 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JPCLEFIL_01403 1.6e-101 recN L Putative cell-wall binding lipoprotein
JPCLEFIL_01404 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JPCLEFIL_01405 0.0 Q Polyketide synthase of type I
JPCLEFIL_01406 0.0 Q polyketide synthase
JPCLEFIL_01407 0.0 Q Polyketide synthase of type I
JPCLEFIL_01408 0.0 Q Polyketide synthase of type I
JPCLEFIL_01409 0.0 Q Polyketide synthase of type I
JPCLEFIL_01410 0.0 Q Polyketide synthase of type I
JPCLEFIL_01411 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
JPCLEFIL_01412 1.9e-208 V Beta-lactamase
JPCLEFIL_01413 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JPCLEFIL_01414 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JPCLEFIL_01415 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JPCLEFIL_01416 1.2e-250 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JPCLEFIL_01417 1.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
JPCLEFIL_01418 4.6e-135 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
JPCLEFIL_01419 9.2e-11 S SR1 protein
JPCLEFIL_01420 7.2e-275 speA 4.1.1.19 E Arginine
JPCLEFIL_01421 1.6e-42 yktA S Belongs to the UPF0223 family
JPCLEFIL_01422 1.8e-118 yktB S Belongs to the UPF0637 family
JPCLEFIL_01423 6.3e-24 ykzI
JPCLEFIL_01424 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
JPCLEFIL_01425 4e-83 ykzC S Acetyltransferase (GNAT) family
JPCLEFIL_01426 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
JPCLEFIL_01427 2.2e-13 sigC S Putative zinc-finger
JPCLEFIL_01428 1.3e-36 ylaE
JPCLEFIL_01429 6.7e-24 S Family of unknown function (DUF5325)
JPCLEFIL_01430 0.0 typA T GTP-binding protein TypA
JPCLEFIL_01431 6.6e-48 ylaH S YlaH-like protein
JPCLEFIL_01432 1.4e-33 ylaI S protein conserved in bacteria
JPCLEFIL_01433 5.7e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JPCLEFIL_01434 6e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
JPCLEFIL_01435 8.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JPCLEFIL_01436 5.2e-47 glsA 3.5.1.2 E Belongs to the glutaminase family
JPCLEFIL_01437 2.8e-123 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JPCLEFIL_01438 1.3e-27 O Glutaredoxin
JPCLEFIL_01440 8.1e-10
JPCLEFIL_01441 2.3e-57 ymaB S MutT family
JPCLEFIL_01446 9.4e-09 S Protein of unknown function (DUF1643)
JPCLEFIL_01447 7.4e-131 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JPCLEFIL_01448 4.9e-29 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JPCLEFIL_01452 4.9e-61
JPCLEFIL_01456 4.9e-23 sspB S spore protein
JPCLEFIL_01457 2.2e-151 S Calcineurin-like phosphoesterase
JPCLEFIL_01459 3.5e-09
JPCLEFIL_01467 1.4e-11 V Restriction endonuclease
JPCLEFIL_01469 3.8e-91 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JPCLEFIL_01471 4e-159 pbuX F xanthine
JPCLEFIL_01473 2.7e-97 yrdC 3.5.1.19 Q Isochorismatase family
JPCLEFIL_01474 5.3e-48 ydfR S Protein of unknown function (DUF421)
JPCLEFIL_01475 1.1e-21 ydfR S Protein of unknown function (DUF421)
JPCLEFIL_01477 5.2e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
JPCLEFIL_01478 3.5e-106 J Acetyltransferase (GNAT) domain
JPCLEFIL_01479 9.4e-203 bcsA Q Naringenin-chalcone synthase
JPCLEFIL_01480 7.2e-89 ypbQ S protein conserved in bacteria
JPCLEFIL_01481 0.0 ypbR S Dynamin family
JPCLEFIL_01482 2.2e-38 ypbS S Protein of unknown function (DUF2533)
JPCLEFIL_01484 3.5e-163 polA 2.7.7.7 L 5'3' exonuclease
JPCLEFIL_01486 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
JPCLEFIL_01487 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JPCLEFIL_01488 2.6e-123 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
JPCLEFIL_01489 1.5e-28 ypeQ S Zinc-finger
JPCLEFIL_01490 1.2e-36 S Protein of unknown function (DUF2564)
JPCLEFIL_01491 1.3e-11 degR
JPCLEFIL_01492 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
JPCLEFIL_01493 5.2e-49 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JPCLEFIL_01494 3.5e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JPCLEFIL_01495 3.1e-99 ypgQ S phosphohydrolase
JPCLEFIL_01496 2.2e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
JPCLEFIL_01497 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JPCLEFIL_01498 1e-75 yphP S Belongs to the UPF0403 family
JPCLEFIL_01499 4.4e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
JPCLEFIL_01500 8.5e-113 ypjP S YpjP-like protein
JPCLEFIL_01501 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JPCLEFIL_01502 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JPCLEFIL_01503 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JPCLEFIL_01504 1.6e-109 hlyIII S protein, Hemolysin III
JPCLEFIL_01505 8.3e-174 pspF K Transcriptional regulator
JPCLEFIL_01506 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JPCLEFIL_01507 3.2e-37 ypmP S Protein of unknown function (DUF2535)
JPCLEFIL_01508 7.9e-114 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
JPCLEFIL_01509 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
JPCLEFIL_01510 6.1e-97 ypmS S protein conserved in bacteria
JPCLEFIL_01511 1.4e-66 ypoP K transcriptional
JPCLEFIL_01512 1.2e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JPCLEFIL_01513 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JPCLEFIL_01514 2.3e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
JPCLEFIL_01515 4.9e-304 yokA L Recombinase
JPCLEFIL_01517 2.1e-89 yokH G SMI1 / KNR4 family
JPCLEFIL_01518 6.6e-111 xkdP S Lysin motif
JPCLEFIL_01519 2e-185 xkdO L Transglycosylase SLT domain
JPCLEFIL_01520 0.0 srfAC Q TIGRFAM amino acid adenylation domain
JPCLEFIL_01521 2.3e-137 spoVID M stage VI sporulation protein D
JPCLEFIL_01522 9.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JPCLEFIL_01523 2.1e-25
JPCLEFIL_01524 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JPCLEFIL_01525 1.6e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JPCLEFIL_01526 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
JPCLEFIL_01527 6.9e-136 spoIIB S Sporulation related domain
JPCLEFIL_01528 2.1e-97 maf D septum formation protein Maf
JPCLEFIL_01529 5.3e-127 radC E Belongs to the UPF0758 family
JPCLEFIL_01530 4e-184 mreB D Rod shape-determining protein MreB
JPCLEFIL_01531 3.6e-157 mreC M Involved in formation and maintenance of cell shape
JPCLEFIL_01532 5.4e-84 mreD M shape-determining protein
JPCLEFIL_01533 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
JPCLEFIL_01534 2.3e-142 minD D Belongs to the ParA family
JPCLEFIL_01535 6.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
JPCLEFIL_01536 3e-159 spoIVFB S Stage IV sporulation protein
JPCLEFIL_01537 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
JPCLEFIL_01538 3.2e-56 ysxB J ribosomal protein
JPCLEFIL_01539 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JPCLEFIL_01540 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
JPCLEFIL_01541 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JPCLEFIL_01542 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
JPCLEFIL_01543 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
JPCLEFIL_01544 3e-93 niaR S small molecule binding protein (contains 3H domain)
JPCLEFIL_01545 2.8e-221 nifS 2.8.1.7 E Cysteine desulfurase
JPCLEFIL_01546 4.8e-293 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
JPCLEFIL_01547 7.6e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
JPCLEFIL_01548 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JPCLEFIL_01549 3.9e-125 safA M spore coat assembly protein SafA
JPCLEFIL_01550 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JPCLEFIL_01552 3.7e-93 bofC S BofC C-terminal domain
JPCLEFIL_01553 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JPCLEFIL_01554 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JPCLEFIL_01555 1.6e-20 yrzS S Protein of unknown function (DUF2905)
JPCLEFIL_01556 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JPCLEFIL_01557 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JPCLEFIL_01558 2.5e-37 yajC U Preprotein translocase subunit YajC
JPCLEFIL_01559 2.4e-60 yrzE S Protein of unknown function (DUF3792)
JPCLEFIL_01560 9.5e-110 yrbG S membrane
JPCLEFIL_01561 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JPCLEFIL_01562 8.5e-50 yrzD S Post-transcriptional regulator
JPCLEFIL_01563 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JPCLEFIL_01564 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
JPCLEFIL_01565 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
JPCLEFIL_01566 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JPCLEFIL_01567 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JPCLEFIL_01568 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JPCLEFIL_01569 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JPCLEFIL_01570 2.5e-273 lytH 3.5.1.28 M COG3103 SH3 domain protein
JPCLEFIL_01573 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
JPCLEFIL_01574 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JPCLEFIL_01575 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
JPCLEFIL_01576 2.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
JPCLEFIL_01577 7.8e-64 cymR K Transcriptional regulator
JPCLEFIL_01578 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
JPCLEFIL_01579 1.2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JPCLEFIL_01580 1.7e-18 S COG0457 FOG TPR repeat
JPCLEFIL_01581 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JPCLEFIL_01582 3.4e-82 yrrD S protein conserved in bacteria
JPCLEFIL_01583 2.9e-30 yrzR
JPCLEFIL_01584 2.1e-08 S Protein of unknown function (DUF3918)
JPCLEFIL_01585 4.9e-106 glnP P ABC transporter
JPCLEFIL_01586 6.1e-109 gluC P ABC transporter
JPCLEFIL_01587 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
JPCLEFIL_01588 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JPCLEFIL_01589 2e-162 yrrI S AI-2E family transporter
JPCLEFIL_01590 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JPCLEFIL_01591 8.5e-41 yrzL S Belongs to the UPF0297 family
JPCLEFIL_01592 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JPCLEFIL_01593 7.1e-46 yrzB S Belongs to the UPF0473 family
JPCLEFIL_01594 1.2e-189 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JPCLEFIL_01595 1.2e-117 yrrM 2.1.1.104 S O-methyltransferase
JPCLEFIL_01596 2.9e-173 yegQ O Peptidase U32
JPCLEFIL_01597 3.9e-245 yegQ O COG0826 Collagenase and related proteases
JPCLEFIL_01598 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
JPCLEFIL_01599 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JPCLEFIL_01600 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
JPCLEFIL_01601 8.1e-70 yrrS S Protein of unknown function (DUF1510)
JPCLEFIL_01602 5.3e-27 yrzA S Protein of unknown function (DUF2536)
JPCLEFIL_01603 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
JPCLEFIL_01604 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JPCLEFIL_01605 2.6e-169 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
JPCLEFIL_01606 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JPCLEFIL_01607 5.1e-34 yrhC S YrhC-like protein
JPCLEFIL_01608 7e-81 yrhD S Protein of unknown function (DUF1641)
JPCLEFIL_01609 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
JPCLEFIL_01610 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
JPCLEFIL_01611 8e-143 focA P Formate nitrite
JPCLEFIL_01613 6.7e-93 yrhH Q methyltransferase
JPCLEFIL_01614 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
JPCLEFIL_01615 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JPCLEFIL_01616 1.9e-212 ynfM EGP Major facilitator Superfamily
JPCLEFIL_01617 5.9e-163 yybE K Transcriptional regulator
JPCLEFIL_01618 1.4e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JPCLEFIL_01619 1.4e-180 romA S Beta-lactamase superfamily domain
JPCLEFIL_01620 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
JPCLEFIL_01621 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
JPCLEFIL_01622 1.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
JPCLEFIL_01623 2.3e-128 glvR K Helix-turn-helix domain, rpiR family
JPCLEFIL_01624 2.3e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
JPCLEFIL_01625 2.7e-143 S hydrolase
JPCLEFIL_01626 1.5e-91 yrdA S DinB family
JPCLEFIL_01627 8.7e-82 yyaR K Acetyltransferase (GNAT) domain
JPCLEFIL_01628 1.4e-219 tetL EGP Major facilitator Superfamily
JPCLEFIL_01629 1.7e-96 adk 2.7.4.3 F adenylate kinase activity
JPCLEFIL_01631 3.2e-81 ydeE K AraC family transcriptional regulator
JPCLEFIL_01632 3.9e-58 ydeE K AraC family transcriptional regulator
JPCLEFIL_01633 8e-91 K Transcriptional regulator PadR-like family
JPCLEFIL_01634 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
JPCLEFIL_01635 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JPCLEFIL_01636 1.8e-210 EGP Major facilitator Superfamily
JPCLEFIL_01637 8e-106 yqeD S SNARE associated Golgi protein
JPCLEFIL_01638 4.2e-138 3.5.1.104 G Polysaccharide deacetylase
JPCLEFIL_01639 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
JPCLEFIL_01641 7.6e-94 yqeG S hydrolase of the HAD superfamily
JPCLEFIL_01642 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JPCLEFIL_01643 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JPCLEFIL_01644 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
JPCLEFIL_01645 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JPCLEFIL_01646 7.2e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JPCLEFIL_01647 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JPCLEFIL_01648 1.1e-138 yqeM Q Methyltransferase
JPCLEFIL_01649 3.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JPCLEFIL_01650 8.9e-102 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
JPCLEFIL_01651 8e-105 comEB 3.5.4.12 F ComE operon protein 2
JPCLEFIL_01652 0.0 comEC S Competence protein ComEC
JPCLEFIL_01653 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
JPCLEFIL_01654 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
JPCLEFIL_01655 6.6e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JPCLEFIL_01656 1.7e-218 spoIIP M stage II sporulation protein P
JPCLEFIL_01657 2.5e-53 yqxA S Protein of unknown function (DUF3679)
JPCLEFIL_01658 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JPCLEFIL_01659 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
JPCLEFIL_01660 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JPCLEFIL_01661 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JPCLEFIL_01662 0.0 dnaK O Heat shock 70 kDa protein
JPCLEFIL_01663 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JPCLEFIL_01664 6.6e-173 prmA J Methylates ribosomal protein L11
JPCLEFIL_01665 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JPCLEFIL_01666 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
JPCLEFIL_01667 7.3e-156 yqeW P COG1283 Na phosphate symporter
JPCLEFIL_01668 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JPCLEFIL_01669 8e-68 yqeY S Yqey-like protein
JPCLEFIL_01670 2e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
JPCLEFIL_01671 3.8e-118 yqfA S UPF0365 protein
JPCLEFIL_01672 5.3e-40 yqfB
JPCLEFIL_01673 9.3e-46 yqfC S sporulation protein YqfC
JPCLEFIL_01674 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
JPCLEFIL_01675 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
JPCLEFIL_01676 0.0 yqfF S membrane-associated HD superfamily hydrolase
JPCLEFIL_01677 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JPCLEFIL_01678 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JPCLEFIL_01679 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JPCLEFIL_01680 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JPCLEFIL_01681 1.8e-16 S YqzL-like protein
JPCLEFIL_01682 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
JPCLEFIL_01683 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JPCLEFIL_01684 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JPCLEFIL_01685 4.5e-112 ccpN K CBS domain
JPCLEFIL_01686 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JPCLEFIL_01687 1.3e-87 yaiI S Belongs to the UPF0178 family
JPCLEFIL_01688 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JPCLEFIL_01689 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JPCLEFIL_01690 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
JPCLEFIL_01691 2.9e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
JPCLEFIL_01692 2.1e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JPCLEFIL_01693 6.5e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JPCLEFIL_01694 3.7e-43 yqfQ S YqfQ-like protein
JPCLEFIL_01695 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JPCLEFIL_01696 1.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JPCLEFIL_01697 9.3e-37 yqfT S Protein of unknown function (DUF2624)
JPCLEFIL_01698 5.9e-155 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JPCLEFIL_01699 2.9e-72 zur P Belongs to the Fur family
JPCLEFIL_01700 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
JPCLEFIL_01701 2.3e-52 yqfX S membrane
JPCLEFIL_01702 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JPCLEFIL_01703 2.6e-46 yqfZ M LysM domain
JPCLEFIL_01704 1.1e-130 yqgB S Protein of unknown function (DUF1189)
JPCLEFIL_01705 2.9e-71 yqgC S protein conserved in bacteria
JPCLEFIL_01706 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
JPCLEFIL_01707 3.4e-228 yqgE EGP Major facilitator superfamily
JPCLEFIL_01708 0.0 pbpA 3.4.16.4 M penicillin-binding protein
JPCLEFIL_01709 7.6e-158 pstS P Phosphate
JPCLEFIL_01710 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
JPCLEFIL_01711 2.9e-154 pstA P Phosphate transport system permease
JPCLEFIL_01712 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JPCLEFIL_01713 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JPCLEFIL_01714 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JPCLEFIL_01715 1.2e-50 yqzD
JPCLEFIL_01716 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JPCLEFIL_01717 1.3e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JPCLEFIL_01718 4e-07 yqgO
JPCLEFIL_01719 5.9e-231 nhaC C Na H antiporter
JPCLEFIL_01720 8.5e-28 yqgQ S Protein conserved in bacteria
JPCLEFIL_01721 2.2e-179 glcK 2.7.1.2 G Glucokinase
JPCLEFIL_01722 1.2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
JPCLEFIL_01723 3.3e-197 yqgU
JPCLEFIL_01724 6.9e-50 yqgV S Thiamine-binding protein
JPCLEFIL_01725 5.4e-20 yqgW S Protein of unknown function (DUF2759)
JPCLEFIL_01726 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JPCLEFIL_01727 3.1e-37 yqgY S Protein of unknown function (DUF2626)
JPCLEFIL_01728 1.6e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
JPCLEFIL_01730 9.4e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JPCLEFIL_01731 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JPCLEFIL_01732 1.2e-185 corA P Mg2 transporter protein
JPCLEFIL_01733 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JPCLEFIL_01734 7.8e-183 comGB NU COG1459 Type II secretory pathway, component PulF
JPCLEFIL_01735 8.9e-50 comGC U Required for transformation and DNA binding
JPCLEFIL_01736 8.4e-70 gspH NU Tfp pilus assembly protein FimT
JPCLEFIL_01737 2e-20 comGE
JPCLEFIL_01738 2.5e-65 comGF U Putative Competence protein ComGF
JPCLEFIL_01739 2.1e-61 S ComG operon protein 7
JPCLEFIL_01740 2.3e-26 yqzE S YqzE-like protein
JPCLEFIL_01741 1.1e-53 yqzG S Protein of unknown function (DUF3889)
JPCLEFIL_01742 1.2e-120 yqxM
JPCLEFIL_01743 3.5e-71 sipW 3.4.21.89 U Signal peptidase
JPCLEFIL_01744 4.7e-140 tasA S Cell division protein FtsN
JPCLEFIL_01745 7.8e-55 sinR K transcriptional
JPCLEFIL_01746 5.2e-23 sinI S Anti-repressor SinI
JPCLEFIL_01747 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
JPCLEFIL_01748 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JPCLEFIL_01749 2.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
JPCLEFIL_01750 5.1e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JPCLEFIL_01751 3.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JPCLEFIL_01752 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
JPCLEFIL_01753 4.9e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
JPCLEFIL_01754 3e-72 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
JPCLEFIL_01755 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
JPCLEFIL_01756 5.8e-62 yqhP
JPCLEFIL_01757 8e-174 yqhQ S Protein of unknown function (DUF1385)
JPCLEFIL_01758 3.7e-88 yqhR S Conserved membrane protein YqhR
JPCLEFIL_01759 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JPCLEFIL_01760 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JPCLEFIL_01761 1.8e-36 yqhV S Protein of unknown function (DUF2619)
JPCLEFIL_01762 5.5e-172 spoIIIAA S stage III sporulation protein AA
JPCLEFIL_01763 1.6e-83 spoIIIAB S Stage III sporulation protein
JPCLEFIL_01764 7.6e-29 spoIIIAC S stage III sporulation protein AC
JPCLEFIL_01765 2.5e-41 spoIIIAD S Stage III sporulation protein AD
JPCLEFIL_01766 6.3e-200 spoIIIAE S stage III sporulation protein AE
JPCLEFIL_01767 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
JPCLEFIL_01768 1.1e-116 spoIIIAG S stage III sporulation protein AG
JPCLEFIL_01769 2.5e-62 spoIIIAH S SpoIIIAH-like protein
JPCLEFIL_01770 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JPCLEFIL_01771 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JPCLEFIL_01772 8.1e-67 yqhY S protein conserved in bacteria
JPCLEFIL_01773 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JPCLEFIL_01774 5.7e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JPCLEFIL_01775 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JPCLEFIL_01776 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JPCLEFIL_01777 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JPCLEFIL_01778 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JPCLEFIL_01779 4.3e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
JPCLEFIL_01780 3.9e-78 argR K Regulates arginine biosynthesis genes
JPCLEFIL_01781 3e-304 recN L May be involved in recombinational repair of damaged DNA
JPCLEFIL_01782 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
JPCLEFIL_01783 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
JPCLEFIL_01784 2.6e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JPCLEFIL_01787 1.6e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
JPCLEFIL_01789 1.2e-112 K Protein of unknown function (DUF1232)
JPCLEFIL_01790 3.4e-101 ytaF P Probably functions as a manganese efflux pump
JPCLEFIL_01791 2.1e-16
JPCLEFIL_01792 2.3e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
JPCLEFIL_01793 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JPCLEFIL_01794 1.8e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
JPCLEFIL_01795 6.3e-154 hbdA 1.1.1.157 I Dehydrogenase
JPCLEFIL_01796 1.4e-204 mmgC I acyl-CoA dehydrogenase
JPCLEFIL_01797 1.2e-202 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
JPCLEFIL_01798 2.7e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
JPCLEFIL_01799 2.4e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JPCLEFIL_01800 3.2e-34 yqzF S Protein of unknown function (DUF2627)
JPCLEFIL_01801 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
JPCLEFIL_01802 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
JPCLEFIL_01803 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
JPCLEFIL_01804 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
JPCLEFIL_01805 2.9e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JPCLEFIL_01806 2.1e-161 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JPCLEFIL_01807 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JPCLEFIL_01808 2e-201 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JPCLEFIL_01809 1.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JPCLEFIL_01810 1e-75 yqiW S Belongs to the UPF0403 family
JPCLEFIL_01811 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
JPCLEFIL_01812 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
JPCLEFIL_01813 1.5e-127 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JPCLEFIL_01814 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
JPCLEFIL_01815 3.1e-95 yqjB S protein conserved in bacteria
JPCLEFIL_01817 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
JPCLEFIL_01818 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JPCLEFIL_01819 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
JPCLEFIL_01820 3.5e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JPCLEFIL_01821 4.1e-25 yqzJ
JPCLEFIL_01822 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPCLEFIL_01823 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JPCLEFIL_01824 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JPCLEFIL_01825 1.8e-170 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JPCLEFIL_01826 1.1e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JPCLEFIL_01827 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
JPCLEFIL_01828 1.6e-49 S GlpM protein
JPCLEFIL_01829 1.4e-161 K LysR substrate binding domain
JPCLEFIL_01830 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
JPCLEFIL_01831 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JPCLEFIL_01834 3.5e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JPCLEFIL_01835 1.1e-127 IQ reductase
JPCLEFIL_01836 0.0 pksJ Q Polyketide synthase of type I
JPCLEFIL_01837 0.0 pksJ Q Polyketide synthase of type I
JPCLEFIL_01838 0.0 1.1.1.320 Q Polyketide synthase of type I
JPCLEFIL_01839 0.0 Q Polyketide synthase of type I
JPCLEFIL_01840 0.0 pksJ Q Polyketide synthase of type I
JPCLEFIL_01841 0.0 pfaA Q Polyketide synthase of type I
JPCLEFIL_01842 0.0 Q Polyketide synthase of type I
JPCLEFIL_01843 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JPCLEFIL_01844 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
JPCLEFIL_01845 3.7e-238 pksG 2.3.3.10 I synthase
JPCLEFIL_01846 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
JPCLEFIL_01847 6.9e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JPCLEFIL_01848 3.6e-174 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
JPCLEFIL_01849 1.6e-140 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
JPCLEFIL_01850 3.1e-248 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
JPCLEFIL_01851 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
JPCLEFIL_01852 5.6e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JPCLEFIL_01854 1.3e-185 yueF S transporter activity
JPCLEFIL_01856 2.1e-55 S YolD-like protein
JPCLEFIL_01857 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPCLEFIL_01858 8.7e-89 yqjY K acetyltransferase
JPCLEFIL_01859 2.8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
JPCLEFIL_01860 1.2e-172 yqkA K GrpB protein
JPCLEFIL_01861 1.7e-60 yqkB S Belongs to the HesB IscA family
JPCLEFIL_01862 3.2e-39 yqkC S Protein of unknown function (DUF2552)
JPCLEFIL_01863 5.8e-174 yqkD S COG1073 Hydrolases of the alpha beta superfamily
JPCLEFIL_01865 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
JPCLEFIL_01867 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
JPCLEFIL_01868 4e-220 yqxK 3.6.4.12 L DNA helicase
JPCLEFIL_01869 1e-57 ansR K Transcriptional regulator
JPCLEFIL_01870 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
JPCLEFIL_01871 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
JPCLEFIL_01872 1.6e-239 mleN C Na H antiporter
JPCLEFIL_01873 3.8e-243 mleA 1.1.1.38 C malic enzyme
JPCLEFIL_01874 5.7e-22
JPCLEFIL_01875 7.3e-33 yqkK
JPCLEFIL_01877 7.2e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
JPCLEFIL_01878 1.9e-80 fur P Belongs to the Fur family
JPCLEFIL_01879 3.7e-37 S Protein of unknown function (DUF4227)
JPCLEFIL_01880 2.8e-165 xerD L recombinase XerD
JPCLEFIL_01881 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JPCLEFIL_01882 2.4e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JPCLEFIL_01883 1.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
JPCLEFIL_01884 6.6e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
JPCLEFIL_01885 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
JPCLEFIL_01886 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JPCLEFIL_01887 4.8e-111 spoVAA S Stage V sporulation protein AA
JPCLEFIL_01888 5.1e-60 spoVAB S Stage V sporulation protein AB
JPCLEFIL_01889 6e-79 spoVAC S stage V sporulation protein AC
JPCLEFIL_01890 1.2e-188 spoVAD I Stage V sporulation protein AD
JPCLEFIL_01891 5e-57 spoVAEB S stage V sporulation protein
JPCLEFIL_01892 1.1e-109 spoVAEA S stage V sporulation protein
JPCLEFIL_01893 3.2e-270 spoVAF EG Stage V sporulation protein AF
JPCLEFIL_01894 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JPCLEFIL_01895 1.9e-153 ypuA S Secreted protein
JPCLEFIL_01896 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JPCLEFIL_01897 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
JPCLEFIL_01898 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JPCLEFIL_01899 1.4e-48 ypuD
JPCLEFIL_01900 3.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JPCLEFIL_01901 2.2e-111 ribE 2.5.1.9 H Riboflavin synthase
JPCLEFIL_01902 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JPCLEFIL_01903 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JPCLEFIL_01904 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPCLEFIL_01905 4.9e-93 ypuF S Domain of unknown function (DUF309)
JPCLEFIL_01907 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JPCLEFIL_01908 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JPCLEFIL_01909 3.8e-93 ypuI S Protein of unknown function (DUF3907)
JPCLEFIL_01910 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
JPCLEFIL_01911 2e-103 spmA S Spore maturation protein
JPCLEFIL_01912 1.3e-88 spmB S Spore maturation protein
JPCLEFIL_01913 1.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JPCLEFIL_01914 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
JPCLEFIL_01915 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
JPCLEFIL_01916 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
JPCLEFIL_01917 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_01918 0.0 resE 2.7.13.3 T Histidine kinase
JPCLEFIL_01919 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
JPCLEFIL_01920 2.6e-192 rsiX
JPCLEFIL_01921 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JPCLEFIL_01922 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JPCLEFIL_01923 3.6e-41 fer C Ferredoxin
JPCLEFIL_01924 1.1e-192 ypbB 5.1.3.1 S protein conserved in bacteria
JPCLEFIL_01925 3e-270 recQ 3.6.4.12 L DNA helicase
JPCLEFIL_01926 4e-99 ypbD S metal-dependent membrane protease
JPCLEFIL_01927 3.2e-80 ypbE M Lysin motif
JPCLEFIL_01928 1.3e-84 ypbF S Protein of unknown function (DUF2663)
JPCLEFIL_01929 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
JPCLEFIL_01930 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JPCLEFIL_01931 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JPCLEFIL_01932 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
JPCLEFIL_01933 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
JPCLEFIL_01934 1.5e-158 sleB 3.5.1.28 M Spore cortex-lytic enzyme
JPCLEFIL_01935 4.6e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
JPCLEFIL_01936 1.4e-60 ypfA M Flagellar protein YcgR
JPCLEFIL_01937 1.4e-12 S Family of unknown function (DUF5359)
JPCLEFIL_01938 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JPCLEFIL_01939 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
JPCLEFIL_01940 3.8e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JPCLEFIL_01941 4.7e-08 S YpzI-like protein
JPCLEFIL_01942 7.2e-104 yphA
JPCLEFIL_01943 4.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JPCLEFIL_01944 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JPCLEFIL_01945 3.3e-16 yphE S Protein of unknown function (DUF2768)
JPCLEFIL_01946 3.1e-133 yphF
JPCLEFIL_01947 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JPCLEFIL_01948 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JPCLEFIL_01949 2.1e-100 folE 3.5.4.16 H GTP cyclohydrolase
JPCLEFIL_01950 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
JPCLEFIL_01951 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
JPCLEFIL_01952 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JPCLEFIL_01953 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JPCLEFIL_01954 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JPCLEFIL_01955 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
JPCLEFIL_01956 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JPCLEFIL_01957 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JPCLEFIL_01958 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
JPCLEFIL_01959 4.2e-289 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JPCLEFIL_01960 8.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JPCLEFIL_01961 1.8e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JPCLEFIL_01962 1.7e-114 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
JPCLEFIL_01963 1.2e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JPCLEFIL_01964 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JPCLEFIL_01965 6.4e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JPCLEFIL_01966 6.6e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JPCLEFIL_01967 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JPCLEFIL_01968 3.5e-233 S COG0457 FOG TPR repeat
JPCLEFIL_01969 2.1e-99 ypiB S Belongs to the UPF0302 family
JPCLEFIL_01970 3.2e-77 ypiF S Protein of unknown function (DUF2487)
JPCLEFIL_01971 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
JPCLEFIL_01972 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
JPCLEFIL_01973 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
JPCLEFIL_01974 3.2e-104 ypjA S membrane
JPCLEFIL_01975 9.5e-141 ypjB S sporulation protein
JPCLEFIL_01976 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
JPCLEFIL_01977 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
JPCLEFIL_01978 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
JPCLEFIL_01979 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JPCLEFIL_01980 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
JPCLEFIL_01981 1.9e-132 bshB1 S proteins, LmbE homologs
JPCLEFIL_01982 8.2e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
JPCLEFIL_01983 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JPCLEFIL_01984 6.9e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JPCLEFIL_01985 6.6e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
JPCLEFIL_01986 2.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JPCLEFIL_01987 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JPCLEFIL_01988 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JPCLEFIL_01989 6.7e-23 ypmA S Protein of unknown function (DUF4264)
JPCLEFIL_01990 1.5e-80 ypmB S protein conserved in bacteria
JPCLEFIL_01991 1.8e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JPCLEFIL_01992 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
JPCLEFIL_01993 3e-130 dnaD L DNA replication protein DnaD
JPCLEFIL_01994 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JPCLEFIL_01995 5.7e-91 ypoC
JPCLEFIL_01996 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPCLEFIL_01997 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JPCLEFIL_01998 2.6e-188 yppC S Protein of unknown function (DUF2515)
JPCLEFIL_02001 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
JPCLEFIL_02003 2.1e-49 yppG S YppG-like protein
JPCLEFIL_02004 7.9e-70 hspX O Belongs to the small heat shock protein (HSP20) family
JPCLEFIL_02005 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
JPCLEFIL_02006 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
JPCLEFIL_02007 2.1e-219 yprB L RNase_H superfamily
JPCLEFIL_02009 9.9e-33 cotD S Inner spore coat protein D
JPCLEFIL_02010 7e-98 ypsA S Belongs to the UPF0398 family
JPCLEFIL_02011 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JPCLEFIL_02012 4.6e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JPCLEFIL_02013 6.6e-22 S YpzG-like protein
JPCLEFIL_02015 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
JPCLEFIL_02016 4.8e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JPCLEFIL_02017 7.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JPCLEFIL_02018 1.3e-64 pbuX F xanthine
JPCLEFIL_02019 1.4e-50 L Recombinase
JPCLEFIL_02020 1.3e-78 yokF 3.1.31.1 L RNA catabolic process
JPCLEFIL_02021 3.3e-92 G SMI1-KNR4 cell-wall
JPCLEFIL_02022 1.3e-166 V HNH endonuclease
JPCLEFIL_02023 5.3e-216 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JPCLEFIL_02024 1e-99 yokK S SMI1 / KNR4 family
JPCLEFIL_02026 9e-40 S YolD-like protein
JPCLEFIL_02027 7.1e-223 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPCLEFIL_02029 7.4e-89 S response regulator aspartate phosphatase
JPCLEFIL_02032 3.1e-32 S Bacteriophage holin
JPCLEFIL_02034 1.3e-76 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JPCLEFIL_02035 1.4e-278 M Pectate lyase superfamily protein
JPCLEFIL_02036 2.6e-93
JPCLEFIL_02038 6.9e-35
JPCLEFIL_02039 1.6e-269 S Pfam Transposase IS66
JPCLEFIL_02040 7.2e-85 S Phage tail protein
JPCLEFIL_02041 3.9e-155 S peptidoglycan catabolic process
JPCLEFIL_02042 6.4e-203 S peptidoglycan catabolic process
JPCLEFIL_02043 8.4e-55
JPCLEFIL_02045 3e-67 S DNA integration
JPCLEFIL_02046 1.1e-50
JPCLEFIL_02047 2.4e-23
JPCLEFIL_02048 6e-81 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
JPCLEFIL_02049 1.6e-13
JPCLEFIL_02050 2e-53 S Domain of unknown function (DUF2479)
JPCLEFIL_02054 9.9e-59 ftsZ D Tubulin/FtsZ family, GTPase domain
JPCLEFIL_02055 2.5e-94
JPCLEFIL_02056 2.8e-216
JPCLEFIL_02064 1.2e-19 I Acyltransferase family
JPCLEFIL_02065 1.4e-69 yoaW
JPCLEFIL_02072 2.2e-24
JPCLEFIL_02076 9.5e-111
JPCLEFIL_02079 3.6e-80
JPCLEFIL_02085 7.8e-37 L Belongs to the 'phage' integrase family
JPCLEFIL_02086 1.6e-188
JPCLEFIL_02087 8.3e-33
JPCLEFIL_02088 2.8e-13 K Transcriptional regulator
JPCLEFIL_02092 4.8e-45 S dUTPase
JPCLEFIL_02096 7.1e-109 kilA S Phage regulatory protein Rha (Phage_pRha)
JPCLEFIL_02099 1.2e-22
JPCLEFIL_02103 2.3e-74
JPCLEFIL_02106 3e-68
JPCLEFIL_02107 9.2e-10 xtmA L phage terminase small subunit
JPCLEFIL_02108 3.1e-57
JPCLEFIL_02109 4.6e-07 S DNA ligase (ATP) activity
JPCLEFIL_02110 1e-137 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
JPCLEFIL_02113 2.4e-26
JPCLEFIL_02115 1.4e-81 S Pfam:DUF867
JPCLEFIL_02116 6.5e-214 M Parallel beta-helix repeats
JPCLEFIL_02119 7.5e-58 mpr 3.4.21.19 M Belongs to the peptidase S1B family
JPCLEFIL_02121 1e-154
JPCLEFIL_02122 5.8e-172 L AAA domain
JPCLEFIL_02123 2.5e-80
JPCLEFIL_02124 1.1e-273 3.6.4.12 J DnaB-like helicase C terminal domain
JPCLEFIL_02125 2.2e-202 L DNA primase activity
JPCLEFIL_02126 1.7e-251 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_02127 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
JPCLEFIL_02128 3.4e-140 srfAD Q thioesterase
JPCLEFIL_02129 3e-248 bamJ E Aminotransferase class I and II
JPCLEFIL_02130 6.1e-128 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
JPCLEFIL_02131 1.7e-108 yczE S membrane
JPCLEFIL_02132 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JPCLEFIL_02133 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
JPCLEFIL_02134 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JPCLEFIL_02135 3.9e-159 bsdA K LysR substrate binding domain
JPCLEFIL_02136 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
JPCLEFIL_02137 3.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
JPCLEFIL_02138 2e-38 bsdD 4.1.1.61 S response to toxic substance
JPCLEFIL_02139 2e-77 yclD
JPCLEFIL_02140 3.2e-270 dtpT E amino acid peptide transporter
JPCLEFIL_02141 7e-277 yclG M Pectate lyase superfamily protein
JPCLEFIL_02143 2.9e-293 gerKA EG Spore germination protein
JPCLEFIL_02144 5.2e-234 gerKC S spore germination
JPCLEFIL_02145 1.1e-195 gerKB F Spore germination protein
JPCLEFIL_02146 1.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPCLEFIL_02147 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPCLEFIL_02148 2.1e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
JPCLEFIL_02149 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
JPCLEFIL_02150 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
JPCLEFIL_02151 1.9e-217 yxeP 3.5.1.47 E hydrolase activity
JPCLEFIL_02152 3.3e-250 yxeQ S MmgE/PrpD family
JPCLEFIL_02153 8.1e-120 yclH P ABC transporter
JPCLEFIL_02154 3.6e-226 yclI V ABC transporter (permease) YclI
JPCLEFIL_02155 6.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_02156 6.4e-260 T PhoQ Sensor
JPCLEFIL_02157 9.5e-81 S aspartate phosphatase
JPCLEFIL_02159 4.5e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
JPCLEFIL_02160 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_02161 8.8e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPCLEFIL_02162 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
JPCLEFIL_02163 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
JPCLEFIL_02164 2.1e-247 ycnB EGP Major facilitator Superfamily
JPCLEFIL_02165 8.7e-151 ycnC K Transcriptional regulator
JPCLEFIL_02166 1.5e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
JPCLEFIL_02167 1e-44 ycnE S Monooxygenase
JPCLEFIL_02168 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
JPCLEFIL_02169 3.7e-260 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JPCLEFIL_02170 4.2e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JPCLEFIL_02171 1.6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JPCLEFIL_02172 3.6e-149 glcU U Glucose uptake
JPCLEFIL_02173 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_02174 2.3e-97 ycnI S protein conserved in bacteria
JPCLEFIL_02175 2e-297 ycnJ P protein, homolog of Cu resistance protein CopC
JPCLEFIL_02176 2.1e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
JPCLEFIL_02177 1.6e-55
JPCLEFIL_02178 2.3e-225 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
JPCLEFIL_02179 5.2e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
JPCLEFIL_02180 1.1e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
JPCLEFIL_02181 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
JPCLEFIL_02183 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JPCLEFIL_02184 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
JPCLEFIL_02185 4.4e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
JPCLEFIL_02186 2.1e-148 ycsI S Belongs to the D-glutamate cyclase family
JPCLEFIL_02187 4.3e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
JPCLEFIL_02188 6e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
JPCLEFIL_02189 1.3e-129 kipR K Transcriptional regulator
JPCLEFIL_02190 6.7e-116 ycsK E anatomical structure formation involved in morphogenesis
JPCLEFIL_02192 5.1e-56 yczJ S biosynthesis
JPCLEFIL_02193 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
JPCLEFIL_02194 1.2e-171 ydhF S Oxidoreductase
JPCLEFIL_02195 0.0 mtlR K transcriptional regulator, MtlR
JPCLEFIL_02196 5.5e-286 ydaB IQ acyl-CoA ligase
JPCLEFIL_02197 5.3e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_02198 3e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
JPCLEFIL_02199 3.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JPCLEFIL_02200 2e-76 ydaG 1.4.3.5 S general stress protein
JPCLEFIL_02201 6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
JPCLEFIL_02202 1.3e-47 ydzA EGP Major facilitator Superfamily
JPCLEFIL_02203 4.3e-74 lrpC K Transcriptional regulator
JPCLEFIL_02204 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JPCLEFIL_02205 3.7e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
JPCLEFIL_02206 5.3e-145 ydaK T Diguanylate cyclase, GGDEF domain
JPCLEFIL_02207 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
JPCLEFIL_02208 7.2e-231 ydaM M Glycosyl transferase family group 2
JPCLEFIL_02209 0.0 ydaN S Bacterial cellulose synthase subunit
JPCLEFIL_02210 0.0 ydaO E amino acid
JPCLEFIL_02211 1.1e-72 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JPCLEFIL_02212 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JPCLEFIL_02214 1.2e-76
JPCLEFIL_02215 4.5e-98
JPCLEFIL_02216 1.8e-38
JPCLEFIL_02217 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
JPCLEFIL_02220 6.5e-34 ydaT
JPCLEFIL_02221 7.9e-54 yvaD S Family of unknown function (DUF5360)
JPCLEFIL_02222 7e-54 yvaE P Small Multidrug Resistance protein
JPCLEFIL_02223 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
JPCLEFIL_02224 5.8e-58 ydbB G Cupin domain
JPCLEFIL_02225 2.3e-57 ydbC S Domain of unknown function (DUF4937
JPCLEFIL_02226 1.2e-154 ydbD P Catalase
JPCLEFIL_02227 6.5e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
JPCLEFIL_02228 4.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JPCLEFIL_02229 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
JPCLEFIL_02230 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JPCLEFIL_02231 4e-158 ydbI S AI-2E family transporter
JPCLEFIL_02232 6.1e-171 ydbJ V ABC transporter, ATP-binding protein
JPCLEFIL_02233 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JPCLEFIL_02234 4.6e-52 ydbL
JPCLEFIL_02235 6.8e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
JPCLEFIL_02236 1.5e-10 S Fur-regulated basic protein B
JPCLEFIL_02237 5.8e-09 S Fur-regulated basic protein A
JPCLEFIL_02238 3.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JPCLEFIL_02239 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JPCLEFIL_02240 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JPCLEFIL_02241 3.5e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JPCLEFIL_02242 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JPCLEFIL_02243 1.3e-60 ydbS S Bacterial PH domain
JPCLEFIL_02244 6.5e-260 ydbT S Membrane
JPCLEFIL_02245 5.3e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
JPCLEFIL_02246 1.7e-55 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JPCLEFIL_02247 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
JPCLEFIL_02248 2.6e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JPCLEFIL_02249 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
JPCLEFIL_02250 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
JPCLEFIL_02251 6.1e-146 rsbR T Positive regulator of sigma-B
JPCLEFIL_02252 1.8e-57 rsbS T antagonist
JPCLEFIL_02253 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
JPCLEFIL_02254 1.7e-187 rsbU 3.1.3.3 KT phosphatase
JPCLEFIL_02255 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
JPCLEFIL_02256 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
JPCLEFIL_02257 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JPCLEFIL_02258 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
JPCLEFIL_02259 0.0 yhgF K COG2183 Transcriptional accessory protein
JPCLEFIL_02260 1.7e-14
JPCLEFIL_02261 1.6e-57 ydcK S Belongs to the SprT family
JPCLEFIL_02269 1.1e-95 ywrO S Flavodoxin-like fold
JPCLEFIL_02270 5.7e-229 proP EGP Transporter
JPCLEFIL_02271 4.5e-137 I esterase
JPCLEFIL_02272 1.3e-46 ohrB O OsmC-like protein
JPCLEFIL_02273 1.4e-48 ohrR K Transcriptional regulator
JPCLEFIL_02274 2.6e-71 ywnA K Transcriptional regulator
JPCLEFIL_02275 3.2e-110 ywnB S NAD(P)H-binding
JPCLEFIL_02276 1.4e-30 cspL K Cold shock
JPCLEFIL_02277 9.2e-40 yrkD S protein conserved in bacteria
JPCLEFIL_02278 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
JPCLEFIL_02279 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
JPCLEFIL_02280 1.5e-200 yrkH P Rhodanese Homology Domain
JPCLEFIL_02281 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
JPCLEFIL_02282 3.6e-116 yrkJ S membrane transporter protein
JPCLEFIL_02283 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JPCLEFIL_02284 1.1e-101 S Protein of unknown function (DUF2812)
JPCLEFIL_02285 2.3e-181 S Patatin-like phospholipase
JPCLEFIL_02286 5.5e-83 S DinB superfamily
JPCLEFIL_02287 5.1e-44 G Cupin domain
JPCLEFIL_02290 1.9e-266 ygaK C COG0277 FAD FMN-containing dehydrogenases
JPCLEFIL_02291 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JPCLEFIL_02292 8.4e-168 czcD P COG1230 Co Zn Cd efflux system component
JPCLEFIL_02293 6.4e-193 trkA P Oxidoreductase
JPCLEFIL_02296 1.8e-14 ykkA S Protein of unknown function (DUF664)
JPCLEFIL_02297 3.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
JPCLEFIL_02299 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
JPCLEFIL_02300 2e-51 ydeH
JPCLEFIL_02301 2.6e-164 S Sodium Bile acid symporter family
JPCLEFIL_02302 3.8e-201 adhA 1.1.1.1 C alcohol dehydrogenase
JPCLEFIL_02303 3.6e-67 yraB K helix_turn_helix, mercury resistance
JPCLEFIL_02304 4.3e-223 mleN_2 C antiporter
JPCLEFIL_02305 8.3e-257 K helix_turn_helix gluconate operon transcriptional repressor
JPCLEFIL_02306 3e-113 paiB K Transcriptional regulator
JPCLEFIL_02308 1.1e-177 ydeR EGP Major facilitator Superfamily
JPCLEFIL_02309 1.2e-100 ydeS K Transcriptional regulator
JPCLEFIL_02310 1.9e-17 ydeS K Transcriptional regulator
JPCLEFIL_02311 1.4e-47 yraD M Spore coat protein
JPCLEFIL_02312 3.1e-24 yraE
JPCLEFIL_02313 9.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JPCLEFIL_02314 2.4e-62 yraF M Spore coat protein
JPCLEFIL_02315 1.3e-35 yraG
JPCLEFIL_02316 1.1e-215 ydfH 2.7.13.3 T Histidine kinase
JPCLEFIL_02317 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPCLEFIL_02318 0.0 ydfJ S drug exporters of the RND superfamily
JPCLEFIL_02319 1.8e-133 puuD S Peptidase C26
JPCLEFIL_02320 1.8e-298 expZ S ABC transporter
JPCLEFIL_02321 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
JPCLEFIL_02322 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
JPCLEFIL_02323 2.3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
JPCLEFIL_02324 1.1e-209 tcaB EGP Major facilitator Superfamily
JPCLEFIL_02325 3.7e-224 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JPCLEFIL_02326 1.9e-155 K Helix-turn-helix XRE-family like proteins
JPCLEFIL_02327 9.4e-122 ydhB S membrane transporter protein
JPCLEFIL_02328 2.2e-81 bltD 2.3.1.57 K FR47-like protein
JPCLEFIL_02329 9e-150 bltR K helix_turn_helix, mercury resistance
JPCLEFIL_02330 1.1e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JPCLEFIL_02331 8.1e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
JPCLEFIL_02332 2e-105 S Alpha/beta hydrolase family
JPCLEFIL_02333 4e-81 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
JPCLEFIL_02336 1.5e-21 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
JPCLEFIL_02337 6.9e-119 ydhC K FCD
JPCLEFIL_02338 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JPCLEFIL_02341 1.3e-262 pbpE V Beta-lactamase
JPCLEFIL_02343 5.5e-98 ydhK M Protein of unknown function (DUF1541)
JPCLEFIL_02344 2e-195 pbuE EGP Major facilitator Superfamily
JPCLEFIL_02345 1.5e-132 ydhQ K UTRA
JPCLEFIL_02346 9.9e-118 K FCD
JPCLEFIL_02347 8.2e-216 yeaN P COG2807 Cyanate permease
JPCLEFIL_02348 7.7e-49 sugE P Small Multidrug Resistance protein
JPCLEFIL_02349 2.3e-51 ykkC P Small Multidrug Resistance protein
JPCLEFIL_02350 2.9e-102 yvdT K Transcriptional regulator
JPCLEFIL_02351 2.1e-296 yveA E amino acid
JPCLEFIL_02352 1.9e-163 ydhU P Catalase
JPCLEFIL_02353 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
JPCLEFIL_02354 6.8e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
JPCLEFIL_02355 1.2e-250 iolT EGP Major facilitator Superfamily
JPCLEFIL_02360 2e-08
JPCLEFIL_02372 1.6e-08
JPCLEFIL_02374 1.6e-08
JPCLEFIL_02382 1.3e-09
JPCLEFIL_02387 7.8e-08
JPCLEFIL_02393 5.8e-77 tspO T membrane
JPCLEFIL_02394 2.4e-130 dksA T COG1734 DnaK suppressor protein
JPCLEFIL_02395 5.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
JPCLEFIL_02396 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JPCLEFIL_02397 7.9e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
JPCLEFIL_02398 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JPCLEFIL_02399 7e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JPCLEFIL_02400 2.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
JPCLEFIL_02401 2e-23 S Domain of Unknown Function (DUF1540)
JPCLEFIL_02402 1.5e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
JPCLEFIL_02403 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
JPCLEFIL_02404 7.9e-41 rpmE2 J Ribosomal protein L31
JPCLEFIL_02405 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JPCLEFIL_02406 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JPCLEFIL_02407 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JPCLEFIL_02408 7.9e-76 ytkA S YtkA-like
JPCLEFIL_02410 7.8e-76 dps P Belongs to the Dps family
JPCLEFIL_02411 5e-61 ytkC S Bacteriophage holin family
JPCLEFIL_02412 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
JPCLEFIL_02413 5.3e-126 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JPCLEFIL_02414 3.2e-144 ytlC P ABC transporter
JPCLEFIL_02415 8.9e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
JPCLEFIL_02416 8e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
JPCLEFIL_02417 1.6e-38 ytmB S Protein of unknown function (DUF2584)
JPCLEFIL_02418 4.5e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JPCLEFIL_02419 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JPCLEFIL_02420 0.0 asnB 6.3.5.4 E Asparagine synthase
JPCLEFIL_02421 1.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
JPCLEFIL_02422 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JPCLEFIL_02423 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
JPCLEFIL_02424 7.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
JPCLEFIL_02425 2.6e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
JPCLEFIL_02427 2.8e-105 ytqB J Putative rRNA methylase
JPCLEFIL_02428 2.1e-190 yhcC S Fe-S oxidoreductase
JPCLEFIL_02429 5.9e-281 norB EGP COG0477 Permeases of the major facilitator superfamily
JPCLEFIL_02430 1.1e-187 K helix_turn_helix, Arsenical Resistance Operon Repressor
JPCLEFIL_02431 7.4e-40 ytzC S Protein of unknown function (DUF2524)
JPCLEFIL_02433 3.9e-66 ytrA K GntR family transcriptional regulator
JPCLEFIL_02434 4.2e-161 ytrB P abc transporter atp-binding protein
JPCLEFIL_02435 5.9e-164 S ABC-2 family transporter protein
JPCLEFIL_02436 3.5e-164 P ABC-2 family transporter protein
JPCLEFIL_02437 3.4e-151
JPCLEFIL_02438 2.2e-125 ytrE V ABC transporter, ATP-binding protein
JPCLEFIL_02439 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
JPCLEFIL_02440 2.8e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_02441 4.1e-170 T PhoQ Sensor
JPCLEFIL_02442 1.4e-133 bceA V ABC transporter, ATP-binding protein
JPCLEFIL_02443 0.0 bceB V ABC transporter (permease)
JPCLEFIL_02444 9e-122 ywaF S Integral membrane protein
JPCLEFIL_02445 2.3e-207 yttB EGP Major facilitator Superfamily
JPCLEFIL_02446 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
JPCLEFIL_02447 1.2e-52 ytvB S Protein of unknown function (DUF4257)
JPCLEFIL_02448 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JPCLEFIL_02449 5.6e-52 ytwF P Sulfurtransferase
JPCLEFIL_02450 1.7e-84 M Acetyltransferase (GNAT) domain
JPCLEFIL_02451 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JPCLEFIL_02452 5.3e-142 amyC P ABC transporter (permease)
JPCLEFIL_02453 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
JPCLEFIL_02454 4.9e-243 msmE G Bacterial extracellular solute-binding protein
JPCLEFIL_02455 4.8e-185 msmR K Transcriptional regulator
JPCLEFIL_02456 9e-26 yteV S Sporulation protein Cse60
JPCLEFIL_02457 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
JPCLEFIL_02458 5.7e-236 ytfP S HI0933-like protein
JPCLEFIL_02459 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JPCLEFIL_02460 2e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JPCLEFIL_02461 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
JPCLEFIL_02462 3.7e-128 ythP V ABC transporter
JPCLEFIL_02463 1.3e-215 ythQ U Bacterial ABC transporter protein EcsB
JPCLEFIL_02464 1.3e-227 pbuO S permease
JPCLEFIL_02465 4e-267 pepV 3.5.1.18 E Dipeptidase
JPCLEFIL_02466 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JPCLEFIL_02467 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JPCLEFIL_02468 1.2e-166 ytlQ
JPCLEFIL_02469 6.8e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
JPCLEFIL_02470 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
JPCLEFIL_02471 3.5e-45 ytzH S YtzH-like protein
JPCLEFIL_02472 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JPCLEFIL_02473 3.3e-163 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
JPCLEFIL_02474 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
JPCLEFIL_02475 1.7e-51 ytzB S small secreted protein
JPCLEFIL_02476 1.7e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JPCLEFIL_02477 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
JPCLEFIL_02478 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JPCLEFIL_02479 8.3e-148 ytpQ S Belongs to the UPF0354 family
JPCLEFIL_02480 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JPCLEFIL_02481 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
JPCLEFIL_02482 4.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JPCLEFIL_02483 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JPCLEFIL_02484 1.7e-16 ytxH S COG4980 Gas vesicle protein
JPCLEFIL_02485 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
JPCLEFIL_02486 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
JPCLEFIL_02487 6.4e-182 ccpA K catabolite control protein A
JPCLEFIL_02488 6.6e-145 motA N flagellar motor
JPCLEFIL_02489 3.7e-120 motS N Flagellar motor protein
JPCLEFIL_02490 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
JPCLEFIL_02491 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
JPCLEFIL_02492 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JPCLEFIL_02493 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JPCLEFIL_02494 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
JPCLEFIL_02495 5.2e-125 azlC E AzlC protein
JPCLEFIL_02496 2.8e-148 K Transcriptional regulator
JPCLEFIL_02497 1.6e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JPCLEFIL_02498 5.2e-136 E GDSL-like Lipase/Acylhydrolase family
JPCLEFIL_02500 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
JPCLEFIL_02501 2.5e-09
JPCLEFIL_02502 7.3e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JPCLEFIL_02503 1.7e-99 yokH G SMI1 / KNR4 family
JPCLEFIL_02504 2.1e-252 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JPCLEFIL_02505 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JPCLEFIL_02506 9.5e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
JPCLEFIL_02507 4.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
JPCLEFIL_02508 1.7e-108 yttP K Transcriptional regulator
JPCLEFIL_02509 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
JPCLEFIL_02510 1.6e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JPCLEFIL_02511 2.6e-239 braB E Component of the transport system for branched-chain amino acids
JPCLEFIL_02512 1.7e-207 iscS2 2.8.1.7 E Cysteine desulfurase
JPCLEFIL_02513 1.6e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JPCLEFIL_02514 3.9e-31 sspB S spore protein
JPCLEFIL_02515 2.1e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JPCLEFIL_02516 0.0 ytcJ S amidohydrolase
JPCLEFIL_02517 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JPCLEFIL_02518 6.4e-182 sppA OU signal peptide peptidase SppA
JPCLEFIL_02519 4.5e-88 yteJ S RDD family
JPCLEFIL_02520 2.6e-89 ytfI S Protein of unknown function (DUF2953)
JPCLEFIL_02521 1.6e-60 ytfJ S Sporulation protein YtfJ
JPCLEFIL_02522 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JPCLEFIL_02523 9.1e-181 ytxK 2.1.1.72 L DNA methylase
JPCLEFIL_02524 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JPCLEFIL_02525 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
JPCLEFIL_02526 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JPCLEFIL_02527 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
JPCLEFIL_02529 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_02530 1.3e-128 ytkL S Belongs to the UPF0173 family
JPCLEFIL_02531 1.6e-236 ytoI K transcriptional regulator containing CBS domains
JPCLEFIL_02532 1.5e-46 ytpI S YtpI-like protein
JPCLEFIL_02533 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
JPCLEFIL_02534 5.8e-23
JPCLEFIL_02535 4.3e-86 ytrI
JPCLEFIL_02536 3.2e-56 ytrH S Sporulation protein YtrH
JPCLEFIL_02537 0.0 dnaE 2.7.7.7 L DNA polymerase
JPCLEFIL_02538 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
JPCLEFIL_02539 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JPCLEFIL_02540 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JPCLEFIL_02541 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JPCLEFIL_02542 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JPCLEFIL_02543 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
JPCLEFIL_02544 6.9e-193 ytvI S sporulation integral membrane protein YtvI
JPCLEFIL_02545 1.1e-72 yeaL S membrane
JPCLEFIL_02546 2.1e-46 yjdF S Protein of unknown function (DUF2992)
JPCLEFIL_02547 1.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
JPCLEFIL_02548 1.2e-241 icd 1.1.1.42 C isocitrate
JPCLEFIL_02549 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
JPCLEFIL_02550 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPCLEFIL_02551 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
JPCLEFIL_02552 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JPCLEFIL_02553 9.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JPCLEFIL_02554 2.1e-106 ytaF P Probably functions as a manganese efflux pump
JPCLEFIL_02555 2.2e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JPCLEFIL_02556 7.6e-160 ytbE S reductase
JPCLEFIL_02557 2.9e-205 ytbD EGP Major facilitator Superfamily
JPCLEFIL_02558 2e-67 ytcD K Transcriptional regulator
JPCLEFIL_02559 9.7e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JPCLEFIL_02560 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JPCLEFIL_02561 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JPCLEFIL_02562 3.1e-251 dnaB L Membrane attachment protein
JPCLEFIL_02563 9.5e-172 dnaI L Primosomal protein DnaI
JPCLEFIL_02564 2.1e-106 ytxB S SNARE associated Golgi protein
JPCLEFIL_02565 2e-152 ytxC S YtxC-like family
JPCLEFIL_02566 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JPCLEFIL_02567 1.1e-149 ysaA S HAD-hyrolase-like
JPCLEFIL_02568 0.0 lytS 2.7.13.3 T Histidine kinase
JPCLEFIL_02569 5.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
JPCLEFIL_02570 2.9e-38 lrgA S effector of murein hydrolase LrgA
JPCLEFIL_02571 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JPCLEFIL_02572 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JPCLEFIL_02573 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JPCLEFIL_02574 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JPCLEFIL_02575 2.6e-42 ysdA S Membrane
JPCLEFIL_02576 1.7e-66 ysdB S Sigma-w pathway protein YsdB
JPCLEFIL_02577 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
JPCLEFIL_02578 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JPCLEFIL_02579 2e-296 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JPCLEFIL_02580 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
JPCLEFIL_02581 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
JPCLEFIL_02582 7.8e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
JPCLEFIL_02583 5.2e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
JPCLEFIL_02584 2.9e-251 araN G carbohydrate transport
JPCLEFIL_02585 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
JPCLEFIL_02586 1.2e-144 araQ G transport system permease
JPCLEFIL_02587 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
JPCLEFIL_02588 0.0 cstA T Carbon starvation protein
JPCLEFIL_02589 2e-255 glcF C Glycolate oxidase
JPCLEFIL_02590 2.9e-257 glcD 1.1.3.15 C FAD binding domain
JPCLEFIL_02591 2.7e-202 ysfB KT regulator
JPCLEFIL_02592 2e-32 sspI S Belongs to the SspI family
JPCLEFIL_02593 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JPCLEFIL_02594 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JPCLEFIL_02595 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JPCLEFIL_02596 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JPCLEFIL_02597 1.2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JPCLEFIL_02598 3.6e-83 cvpA S membrane protein, required for colicin V production
JPCLEFIL_02599 0.0 polX L COG1796 DNA polymerase IV (family X)
JPCLEFIL_02600 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JPCLEFIL_02601 4.7e-67 yshE S membrane
JPCLEFIL_02602 2.1e-96 ywbB S Protein of unknown function (DUF2711)
JPCLEFIL_02603 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JPCLEFIL_02604 2.7e-103 fadR K Transcriptional regulator
JPCLEFIL_02605 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JPCLEFIL_02606 8.2e-137 etfB C Electron transfer flavoprotein
JPCLEFIL_02607 1.6e-177 etfA C Electron transfer flavoprotein
JPCLEFIL_02608 2.8e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JPCLEFIL_02609 2.5e-52 trxA O Belongs to the thioredoxin family
JPCLEFIL_02610 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JPCLEFIL_02611 1.6e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JPCLEFIL_02612 2e-79 yslB S Protein of unknown function (DUF2507)
JPCLEFIL_02613 4.8e-108 sdhC C succinate dehydrogenase
JPCLEFIL_02614 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JPCLEFIL_02615 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JPCLEFIL_02616 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
JPCLEFIL_02617 2e-30 gerE K Transcriptional regulator
JPCLEFIL_02618 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_02619 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JPCLEFIL_02620 5.3e-198 gerM S COG5401 Spore germination protein
JPCLEFIL_02621 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JPCLEFIL_02622 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JPCLEFIL_02623 5.9e-91 ysnB S Phosphoesterase
JPCLEFIL_02627 0.0 ilvB 2.2.1.6 E Acetolactate synthase
JPCLEFIL_02628 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
JPCLEFIL_02629 1.6e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JPCLEFIL_02630 8.7e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JPCLEFIL_02631 9.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JPCLEFIL_02632 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JPCLEFIL_02633 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JPCLEFIL_02634 1e-187 ysoA H Tetratricopeptide repeat
JPCLEFIL_02635 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JPCLEFIL_02636 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JPCLEFIL_02637 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
JPCLEFIL_02638 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JPCLEFIL_02639 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
JPCLEFIL_02640 8.5e-87 ysxD
JPCLEFIL_02641 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JPCLEFIL_02642 1e-145 hemX O cytochrome C
JPCLEFIL_02643 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
JPCLEFIL_02644 1.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JPCLEFIL_02645 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
JPCLEFIL_02646 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JPCLEFIL_02647 2.7e-120 glsA 3.5.1.2 E Belongs to the glutaminase family
JPCLEFIL_02648 8.7e-44 ylaN S Belongs to the UPF0358 family
JPCLEFIL_02649 1.9e-212 ftsW D Belongs to the SEDS family
JPCLEFIL_02650 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JPCLEFIL_02651 4.5e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
JPCLEFIL_02652 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JPCLEFIL_02653 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
JPCLEFIL_02654 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JPCLEFIL_02655 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
JPCLEFIL_02656 1.9e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
JPCLEFIL_02657 2e-163 ctaG S cytochrome c oxidase
JPCLEFIL_02658 3.2e-59 ylbA S YugN-like family
JPCLEFIL_02659 2.2e-73 ylbB T COG0517 FOG CBS domain
JPCLEFIL_02660 8.6e-198 ylbC S protein with SCP PR1 domains
JPCLEFIL_02661 2.1e-54 ylbD S Putative coat protein
JPCLEFIL_02662 8.8e-37 ylbE S YlbE-like protein
JPCLEFIL_02663 1.2e-71 ylbF S Belongs to the UPF0342 family
JPCLEFIL_02664 5.5e-43 ylbG S UPF0298 protein
JPCLEFIL_02665 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
JPCLEFIL_02666 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JPCLEFIL_02667 2e-217 ylbJ S Sporulation integral membrane protein YlbJ
JPCLEFIL_02668 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
JPCLEFIL_02669 1.6e-188 ylbL T Belongs to the peptidase S16 family
JPCLEFIL_02670 4.3e-228 ylbM S Belongs to the UPF0348 family
JPCLEFIL_02671 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
JPCLEFIL_02672 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JPCLEFIL_02673 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
JPCLEFIL_02674 1.2e-88 ylbP K n-acetyltransferase
JPCLEFIL_02675 3.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JPCLEFIL_02676 6.3e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JPCLEFIL_02677 1.2e-77 mraZ K Belongs to the MraZ family
JPCLEFIL_02678 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JPCLEFIL_02679 2.9e-52 ftsL D Essential cell division protein
JPCLEFIL_02680 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JPCLEFIL_02681 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
JPCLEFIL_02682 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JPCLEFIL_02683 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JPCLEFIL_02684 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JPCLEFIL_02685 2.2e-185 spoVE D Belongs to the SEDS family
JPCLEFIL_02686 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JPCLEFIL_02687 1.8e-167 murB 1.3.1.98 M cell wall formation
JPCLEFIL_02688 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JPCLEFIL_02689 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JPCLEFIL_02690 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JPCLEFIL_02691 0.0 bpr O COG1404 Subtilisin-like serine proteases
JPCLEFIL_02692 2.9e-160 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
JPCLEFIL_02693 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JPCLEFIL_02694 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JPCLEFIL_02695 1.6e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
JPCLEFIL_02696 3.7e-251 argE 3.5.1.16 E Acetylornithine deacetylase
JPCLEFIL_02697 2.2e-38 ylmC S sporulation protein
JPCLEFIL_02698 7.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
JPCLEFIL_02699 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JPCLEFIL_02700 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JPCLEFIL_02701 5.2e-41 yggT S membrane
JPCLEFIL_02702 6.1e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
JPCLEFIL_02703 8.9e-68 divIVA D Cell division initiation protein
JPCLEFIL_02704 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JPCLEFIL_02705 1.2e-61 dksA T COG1734 DnaK suppressor protein
JPCLEFIL_02706 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JPCLEFIL_02707 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JPCLEFIL_02708 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JPCLEFIL_02709 8.8e-232 pyrP F Xanthine uracil
JPCLEFIL_02710 2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JPCLEFIL_02711 1.2e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JPCLEFIL_02712 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JPCLEFIL_02713 0.0 carB 6.3.5.5 F Belongs to the CarB family
JPCLEFIL_02714 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JPCLEFIL_02715 5.6e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JPCLEFIL_02716 6.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JPCLEFIL_02717 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JPCLEFIL_02718 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JPCLEFIL_02719 1.1e-176 cysP P phosphate transporter
JPCLEFIL_02720 2.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JPCLEFIL_02721 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
JPCLEFIL_02722 4.5e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JPCLEFIL_02723 2.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
JPCLEFIL_02724 4.6e-77 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
JPCLEFIL_02725 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JPCLEFIL_02726 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
JPCLEFIL_02727 2.5e-153 yloC S stress-induced protein
JPCLEFIL_02728 1.5e-40 ylzA S Belongs to the UPF0296 family
JPCLEFIL_02729 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JPCLEFIL_02730 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JPCLEFIL_02731 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JPCLEFIL_02732 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JPCLEFIL_02733 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JPCLEFIL_02734 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JPCLEFIL_02735 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JPCLEFIL_02736 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JPCLEFIL_02737 2.3e-139 stp 3.1.3.16 T phosphatase
JPCLEFIL_02738 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JPCLEFIL_02739 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JPCLEFIL_02740 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JPCLEFIL_02741 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
JPCLEFIL_02742 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JPCLEFIL_02743 5.5e-59 asp S protein conserved in bacteria
JPCLEFIL_02744 4.9e-304 yloV S kinase related to dihydroxyacetone kinase
JPCLEFIL_02745 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
JPCLEFIL_02746 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
JPCLEFIL_02747 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JPCLEFIL_02748 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
JPCLEFIL_02749 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JPCLEFIL_02750 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JPCLEFIL_02751 4.6e-129 IQ reductase
JPCLEFIL_02752 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JPCLEFIL_02753 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JPCLEFIL_02754 0.0 smc D Required for chromosome condensation and partitioning
JPCLEFIL_02755 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JPCLEFIL_02756 7.9e-140 S Phosphotransferase enzyme family
JPCLEFIL_02757 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JPCLEFIL_02758 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JPCLEFIL_02759 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JPCLEFIL_02760 1.7e-35 ylqC S Belongs to the UPF0109 family
JPCLEFIL_02761 1.3e-61 ylqD S YlqD protein
JPCLEFIL_02762 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JPCLEFIL_02763 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JPCLEFIL_02764 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JPCLEFIL_02765 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JPCLEFIL_02766 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JPCLEFIL_02767 5.2e-301 ylqG
JPCLEFIL_02768 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
JPCLEFIL_02769 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
JPCLEFIL_02770 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JPCLEFIL_02771 2.6e-166 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
JPCLEFIL_02772 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JPCLEFIL_02773 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JPCLEFIL_02774 7.2e-172 xerC L tyrosine recombinase XerC
JPCLEFIL_02775 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JPCLEFIL_02776 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JPCLEFIL_02777 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JPCLEFIL_02778 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
JPCLEFIL_02779 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
JPCLEFIL_02780 2.5e-31 fliE N Flagellar hook-basal body
JPCLEFIL_02781 1.4e-263 fliF N The M ring may be actively involved in energy transduction
JPCLEFIL_02782 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JPCLEFIL_02783 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
JPCLEFIL_02784 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
JPCLEFIL_02785 2e-71 fliJ N Flagellar biosynthesis chaperone
JPCLEFIL_02786 1.3e-47 ylxF S MgtE intracellular N domain
JPCLEFIL_02787 8.8e-203 fliK N Flagellar hook-length control protein
JPCLEFIL_02788 2.4e-72 flgD N Flagellar basal body rod modification protein
JPCLEFIL_02789 5.7e-138 flgG N Flagellar basal body rod
JPCLEFIL_02790 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
JPCLEFIL_02791 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JPCLEFIL_02792 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JPCLEFIL_02793 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
JPCLEFIL_02794 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
JPCLEFIL_02795 3.7e-109 fliP N Plays a role in the flagellum-specific transport system
JPCLEFIL_02796 2e-37 fliQ N Role in flagellar biosynthesis
JPCLEFIL_02797 5.2e-131 fliR N Flagellar biosynthetic protein FliR
JPCLEFIL_02798 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JPCLEFIL_02799 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JPCLEFIL_02800 1.7e-191 flhF N Flagellar biosynthesis regulator FlhF
JPCLEFIL_02801 2.4e-156 flhG D Belongs to the ParA family
JPCLEFIL_02802 2.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
JPCLEFIL_02803 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
JPCLEFIL_02804 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
JPCLEFIL_02805 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
JPCLEFIL_02806 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
JPCLEFIL_02807 2.5e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JPCLEFIL_02808 8e-50 ylxL
JPCLEFIL_02809 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
JPCLEFIL_02810 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JPCLEFIL_02811 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JPCLEFIL_02812 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JPCLEFIL_02813 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JPCLEFIL_02814 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
JPCLEFIL_02815 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
JPCLEFIL_02816 5.9e-233 rasP M zinc metalloprotease
JPCLEFIL_02817 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JPCLEFIL_02818 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JPCLEFIL_02819 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
JPCLEFIL_02820 5.4e-206 nusA K Participates in both transcription termination and antitermination
JPCLEFIL_02821 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
JPCLEFIL_02822 1.8e-47 ylxQ J ribosomal protein
JPCLEFIL_02823 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JPCLEFIL_02824 3.9e-44 ylxP S protein conserved in bacteria
JPCLEFIL_02825 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JPCLEFIL_02826 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JPCLEFIL_02827 1.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JPCLEFIL_02828 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JPCLEFIL_02829 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JPCLEFIL_02830 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
JPCLEFIL_02831 1.2e-233 pepR S Belongs to the peptidase M16 family
JPCLEFIL_02832 2.6e-42 ymxH S YlmC YmxH family
JPCLEFIL_02833 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
JPCLEFIL_02834 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
JPCLEFIL_02835 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JPCLEFIL_02836 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JPCLEFIL_02837 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JPCLEFIL_02838 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JPCLEFIL_02839 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
JPCLEFIL_02840 6.3e-31 S YlzJ-like protein
JPCLEFIL_02841 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JPCLEFIL_02842 4.4e-132 ymfC K Transcriptional regulator
JPCLEFIL_02843 2.6e-195 ymfD EGP Major facilitator Superfamily
JPCLEFIL_02844 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_02845 0.0 ydgH S drug exporters of the RND superfamily
JPCLEFIL_02846 4.4e-236 ymfF S Peptidase M16
JPCLEFIL_02847 3.5e-241 ymfH S zinc protease
JPCLEFIL_02848 3.6e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
JPCLEFIL_02849 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
JPCLEFIL_02850 1e-142 ymfK S Protein of unknown function (DUF3388)
JPCLEFIL_02851 2.5e-124 ymfM S protein conserved in bacteria
JPCLEFIL_02852 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JPCLEFIL_02853 1.6e-230 cinA 3.5.1.42 S Belongs to the CinA family
JPCLEFIL_02854 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JPCLEFIL_02855 1.1e-193 pbpX V Beta-lactamase
JPCLEFIL_02856 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
JPCLEFIL_02857 4.9e-153 ymdB S protein conserved in bacteria
JPCLEFIL_02858 1.2e-36 spoVS S Stage V sporulation protein S
JPCLEFIL_02859 4.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
JPCLEFIL_02860 2.6e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JPCLEFIL_02861 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JPCLEFIL_02862 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JPCLEFIL_02863 1.7e-88 cotE S Spore coat protein
JPCLEFIL_02864 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JPCLEFIL_02865 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JPCLEFIL_02866 1.5e-08 L Phage integrase family
JPCLEFIL_02867 3.5e-40
JPCLEFIL_02868 2.1e-32 V HNH endonuclease
JPCLEFIL_02870 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
JPCLEFIL_02871 7.8e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JPCLEFIL_02872 1.1e-183 pksD Q Acyl transferase domain
JPCLEFIL_02873 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JPCLEFIL_02874 5.5e-34 acpK IQ Phosphopantetheine attachment site
JPCLEFIL_02875 6.9e-242 pksG 2.3.3.10 I synthase
JPCLEFIL_02876 1.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
JPCLEFIL_02877 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
JPCLEFIL_02878 0.0 rhiB IQ polyketide synthase
JPCLEFIL_02879 6.9e-36 Q Polyketide synthase of type I
JPCLEFIL_02880 0.0 Q Polyketide synthase of type I
JPCLEFIL_02881 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
JPCLEFIL_02882 0.0 dhbF IQ polyketide synthase
JPCLEFIL_02883 0.0 pks13 HQ Beta-ketoacyl synthase
JPCLEFIL_02884 8.4e-229 cypA C Cytochrome P450
JPCLEFIL_02885 2.6e-55 nucB M Deoxyribonuclease NucA/NucB
JPCLEFIL_02886 3.6e-118 yoaK S Membrane
JPCLEFIL_02887 4.1e-62 ymzB
JPCLEFIL_02888 2.6e-255 aprX O Belongs to the peptidase S8 family
JPCLEFIL_02890 3e-125 ymaC S Replication protein
JPCLEFIL_02891 6e-79 ymaD O redox protein, regulator of disulfide bond formation
JPCLEFIL_02892 2.6e-53 ebrB P Small Multidrug Resistance protein
JPCLEFIL_02893 2.6e-47 ebrA P Small Multidrug Resistance protein
JPCLEFIL_02895 9.2e-47 ymaF S YmaF family
JPCLEFIL_02896 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JPCLEFIL_02897 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
JPCLEFIL_02898 4.7e-42
JPCLEFIL_02899 1.4e-20 ymzA
JPCLEFIL_02900 1.9e-65 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
JPCLEFIL_02901 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JPCLEFIL_02902 4.7e-185 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JPCLEFIL_02903 7.6e-109 ymaB S MutT family
JPCLEFIL_02904 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JPCLEFIL_02905 1.3e-176 spoVK O stage V sporulation protein K
JPCLEFIL_02906 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JPCLEFIL_02907 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
JPCLEFIL_02908 4.3e-68 glnR K transcriptional
JPCLEFIL_02909 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
JPCLEFIL_02910 6.7e-209 mrjp G Major royal jelly protein
JPCLEFIL_02911 1.9e-248 xynT G MFS/sugar transport protein
JPCLEFIL_02912 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JPCLEFIL_02913 3.7e-210 xylR GK ROK family
JPCLEFIL_02914 1.3e-259 xylA 5.3.1.5 G Belongs to the xylose isomerase family
JPCLEFIL_02916 2.3e-284 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
JPCLEFIL_02917 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
JPCLEFIL_02922 6.3e-185 adhP 1.1.1.1 C alcohol dehydrogenase
JPCLEFIL_02923 2.9e-08 ccmM S Bacterial transferase hexapeptide (six repeats)
JPCLEFIL_02925 6.3e-99 J Acetyltransferase (GNAT) domain
JPCLEFIL_02927 2.3e-113 ynaE S Domain of unknown function (DUF3885)
JPCLEFIL_02928 3.9e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPCLEFIL_02929 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
JPCLEFIL_02931 1.7e-64 2.3.1.128 J Acetyltransferase (GNAT) domain
JPCLEFIL_02932 4.6e-94 yvgO
JPCLEFIL_02934 0.0 yobO M Pectate lyase superfamily protein
JPCLEFIL_02935 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
JPCLEFIL_02936 9.4e-139 yndL S Replication protein
JPCLEFIL_02937 9.1e-08
JPCLEFIL_02938 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
JPCLEFIL_02939 1.2e-71 yndM S Protein of unknown function (DUF2512)
JPCLEFIL_02940 2.1e-12 yoaW
JPCLEFIL_02941 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JPCLEFIL_02942 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
JPCLEFIL_02943 3.5e-112 yneB L resolvase
JPCLEFIL_02944 3.7e-32 ynzC S UPF0291 protein
JPCLEFIL_02945 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JPCLEFIL_02946 1.4e-80 yneE S Sporulation inhibitor of replication protein sirA
JPCLEFIL_02947 2.3e-28 yneF S UPF0154 protein
JPCLEFIL_02948 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
JPCLEFIL_02949 1.7e-125 ccdA O cytochrome c biogenesis protein
JPCLEFIL_02950 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
JPCLEFIL_02951 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
JPCLEFIL_02952 2.5e-74 yneK S Protein of unknown function (DUF2621)
JPCLEFIL_02953 1.1e-62 hspX O Spore coat protein
JPCLEFIL_02954 2.3e-19 sspP S Belongs to the SspP family
JPCLEFIL_02955 7.5e-15 sspO S Belongs to the SspO family
JPCLEFIL_02956 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JPCLEFIL_02957 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JPCLEFIL_02960 7.1e-18 tlp S Belongs to the Tlp family
JPCLEFIL_02961 5.3e-74 yneP S Thioesterase-like superfamily
JPCLEFIL_02962 1.4e-52 yneQ
JPCLEFIL_02963 1.1e-49 yneR S Belongs to the HesB IscA family
JPCLEFIL_02964 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JPCLEFIL_02965 5.6e-68 yccU S CoA-binding protein
JPCLEFIL_02966 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JPCLEFIL_02967 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JPCLEFIL_02968 6e-13
JPCLEFIL_02969 4.7e-39 ynfC
JPCLEFIL_02970 1.2e-245 agcS E Sodium alanine symporter
JPCLEFIL_02971 5.2e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
JPCLEFIL_02972 3.4e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
JPCLEFIL_02973 7.5e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
JPCLEFIL_02974 2.9e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
JPCLEFIL_02975 1.2e-146 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JPCLEFIL_02976 8.6e-179 kdgR_1 K transcriptional
JPCLEFIL_02977 5.7e-220 exuT G Sugar (and other) transporter
JPCLEFIL_02978 5.4e-155 yndG S DoxX-like family
JPCLEFIL_02979 7.3e-80 yndH S Domain of unknown function (DUF4166)
JPCLEFIL_02980 4.1e-295 yndJ S YndJ-like protein
JPCLEFIL_02981 9.6e-15 S Platelet-activating factor acetylhydrolase, isoform II
JPCLEFIL_02982 3.9e-284 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
JPCLEFIL_02983 1.2e-49 S Domain of unknown function (DUF4870)
JPCLEFIL_02984 2.3e-230 T PhoQ Sensor
JPCLEFIL_02985 4.1e-127 T Transcriptional regulatory protein, C terminal
JPCLEFIL_02986 2.4e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
JPCLEFIL_02987 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
JPCLEFIL_02988 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_02989 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_02990 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_02991 8.1e-216 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JPCLEFIL_02992 2.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JPCLEFIL_02993 5.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JPCLEFIL_02994 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JPCLEFIL_02995 4.2e-251 yxjC EG COG2610 H gluconate symporter and related permeases
JPCLEFIL_02996 2.1e-216 bioI 1.14.14.46 C Cytochrome P450
JPCLEFIL_02997 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JPCLEFIL_02998 4.1e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JPCLEFIL_02999 7.6e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JPCLEFIL_03000 3.3e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
JPCLEFIL_03001 1.4e-144 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
JPCLEFIL_03002 9.6e-68 yngA S membrane
JPCLEFIL_03003 8.9e-159 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JPCLEFIL_03004 3.2e-104 yngC S SNARE associated Golgi protein
JPCLEFIL_03005 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JPCLEFIL_03006 1.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JPCLEFIL_03007 3.6e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
JPCLEFIL_03008 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
JPCLEFIL_03009 6.7e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
JPCLEFIL_03010 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JPCLEFIL_03011 1.8e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
JPCLEFIL_03012 3.8e-303 yngK T Glycosyl hydrolase-like 10
JPCLEFIL_03013 1.2e-64 yngL S Protein of unknown function (DUF1360)
JPCLEFIL_03014 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
JPCLEFIL_03015 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_03016 3.6e-94 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_03017 8.1e-226 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_03018 8e-135 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_03019 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_03020 3.9e-268 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
JPCLEFIL_03021 1.5e-183 yoxA 5.1.3.3 G Aldose 1-epimerase
JPCLEFIL_03022 6.7e-246 yoeA V MATE efflux family protein
JPCLEFIL_03023 2.9e-96 yoeB S IseA DL-endopeptidase inhibitor
JPCLEFIL_03025 3.5e-97 L Integrase
JPCLEFIL_03026 1.8e-34 yoeD G Helix-turn-helix domain
JPCLEFIL_03027 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JPCLEFIL_03028 5.7e-198 ybcL EGP Major facilitator Superfamily
JPCLEFIL_03029 3.9e-50 ybzH K Helix-turn-helix domain
JPCLEFIL_03030 1.5e-14 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JPCLEFIL_03031 2.3e-151 gltR1 K Transcriptional regulator
JPCLEFIL_03032 3.7e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JPCLEFIL_03034 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
JPCLEFIL_03035 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
JPCLEFIL_03036 4.5e-150 gltC K Transcriptional regulator
JPCLEFIL_03037 1.8e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JPCLEFIL_03038 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JPCLEFIL_03039 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
JPCLEFIL_03040 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JPCLEFIL_03041 2.4e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JPCLEFIL_03042 1.9e-133 yoxB
JPCLEFIL_03043 1.3e-203 yoaB EGP Major facilitator Superfamily
JPCLEFIL_03044 2.1e-266 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
JPCLEFIL_03045 9.6e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JPCLEFIL_03046 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JPCLEFIL_03049 1.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_03050 6.7e-44
JPCLEFIL_03051 1.9e-130 IQ Enoyl-(Acyl carrier protein) reductase
JPCLEFIL_03052 1.7e-60 ykvN K Transcriptional regulator
JPCLEFIL_03053 1.1e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
JPCLEFIL_03054 4.3e-132 yobQ K helix_turn_helix, arabinose operon control protein
JPCLEFIL_03055 1.2e-92 yobS K Transcriptional regulator
JPCLEFIL_03056 3.6e-134 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
JPCLEFIL_03057 7.1e-92 yobW
JPCLEFIL_03058 8.4e-54 czrA K transcriptional
JPCLEFIL_03059 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JPCLEFIL_03060 3.6e-91 yozB S membrane
JPCLEFIL_03061 8.9e-139 yocB J Protein required for attachment to host cells
JPCLEFIL_03062 1.6e-93 yocC
JPCLEFIL_03063 3.2e-186 yocD 3.4.17.13 V peptidase S66
JPCLEFIL_03065 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
JPCLEFIL_03066 2.2e-298 recQ 3.6.4.12 L DNA helicase
JPCLEFIL_03067 1.5e-29 recQ 3.6.4.12 L DNA helicase
JPCLEFIL_03068 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JPCLEFIL_03070 8.6e-55 dksA T general stress protein
JPCLEFIL_03071 1e-09 yocL
JPCLEFIL_03072 7.5e-09
JPCLEFIL_03073 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
JPCLEFIL_03074 3.8e-44 yozN
JPCLEFIL_03075 8.5e-37 yocN
JPCLEFIL_03076 2.4e-56 yozO S Bacterial PH domain
JPCLEFIL_03078 3.6e-31 yozC
JPCLEFIL_03079 9.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
JPCLEFIL_03080 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
JPCLEFIL_03081 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
JPCLEFIL_03082 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JPCLEFIL_03083 5.1e-160 yocS S -transporter
JPCLEFIL_03084 3.6e-137 S Metallo-beta-lactamase superfamily
JPCLEFIL_03085 1.2e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
JPCLEFIL_03086 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
JPCLEFIL_03087 0.0 yojO P Von Willebrand factor
JPCLEFIL_03088 3.5e-163 yojN S ATPase family associated with various cellular activities (AAA)
JPCLEFIL_03089 2.9e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JPCLEFIL_03090 6.4e-224 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JPCLEFIL_03091 6.9e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
JPCLEFIL_03092 6.3e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JPCLEFIL_03094 6.1e-236 norM V Multidrug efflux pump
JPCLEFIL_03095 3.8e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JPCLEFIL_03096 5.6e-126 yojG S deacetylase
JPCLEFIL_03097 3.7e-60 yojF S Protein of unknown function (DUF1806)
JPCLEFIL_03098 4.9e-23
JPCLEFIL_03099 1.1e-161 rarD S -transporter
JPCLEFIL_03100 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
JPCLEFIL_03102 1.6e-67 yodA S tautomerase
JPCLEFIL_03103 6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
JPCLEFIL_03104 3e-56 yodB K transcriptional
JPCLEFIL_03105 4.5e-106 yodC C nitroreductase
JPCLEFIL_03106 6.3e-108 mhqD S Carboxylesterase
JPCLEFIL_03107 2.2e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
JPCLEFIL_03108 6.9e-19 S Protein of unknown function (DUF3311)
JPCLEFIL_03109 4.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JPCLEFIL_03110 2.9e-279 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
JPCLEFIL_03111 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPCLEFIL_03112 2.6e-132 yydK K Transcriptional regulator
JPCLEFIL_03113 1.1e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
JPCLEFIL_03114 2.8e-128 yodH Q Methyltransferase
JPCLEFIL_03115 1.9e-21 yodI
JPCLEFIL_03116 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JPCLEFIL_03117 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JPCLEFIL_03119 3.3e-55 yodL S YodL-like
JPCLEFIL_03120 3.4e-101 yodM 3.6.1.27 I Acid phosphatase homologues
JPCLEFIL_03121 6.2e-24 yozD S YozD-like protein
JPCLEFIL_03123 1.7e-125 yodN
JPCLEFIL_03124 5.5e-27 E lactoylglutathione lyase activity
JPCLEFIL_03125 9.1e-36 yozE S Belongs to the UPF0346 family
JPCLEFIL_03126 9.2e-46 yokU S YokU-like protein, putative antitoxin
JPCLEFIL_03127 2.3e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
JPCLEFIL_03128 1.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
JPCLEFIL_03129 7.6e-252 yodQ 3.5.1.16 E Acetylornithine deacetylase
JPCLEFIL_03130 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JPCLEFIL_03131 8.4e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JPCLEFIL_03132 1.1e-72 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JPCLEFIL_03133 1.6e-130 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JPCLEFIL_03134 4.1e-64 yosT L Bacterial transcription activator, effector binding domain
JPCLEFIL_03136 1.4e-144 yiiD K acetyltransferase
JPCLEFIL_03137 1.9e-239 cgeD M maturation of the outermost layer of the spore
JPCLEFIL_03138 1.2e-40 cgeC
JPCLEFIL_03139 1.6e-52 cgeA
JPCLEFIL_03140 1.2e-164 cgeB S Spore maturation protein
JPCLEFIL_03141 7.5e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
JPCLEFIL_03142 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
JPCLEFIL_03147 1.7e-77
JPCLEFIL_03148 1.8e-18 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
JPCLEFIL_03149 2.6e-08
JPCLEFIL_03152 5.3e-75 yoqH M LysM domain
JPCLEFIL_03153 1.9e-206 S aspartate phosphatase
JPCLEFIL_03156 4e-155 3.4.24.40 S amine dehydrogenase activity
JPCLEFIL_03159 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JPCLEFIL_03160 1.7e-187 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JPCLEFIL_03161 4.5e-29 yazB K transcriptional
JPCLEFIL_03162 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JPCLEFIL_03163 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JPCLEFIL_03164 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JPCLEFIL_03165 6.5e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
JPCLEFIL_03166 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
JPCLEFIL_03167 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JPCLEFIL_03168 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JPCLEFIL_03169 1.1e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
JPCLEFIL_03170 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JPCLEFIL_03171 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JPCLEFIL_03172 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JPCLEFIL_03173 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JPCLEFIL_03174 6.8e-270 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JPCLEFIL_03175 1.4e-184 KLT serine threonine protein kinase
JPCLEFIL_03176 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
JPCLEFIL_03177 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
JPCLEFIL_03180 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
JPCLEFIL_03181 4.1e-57 divIC D Septum formation initiator
JPCLEFIL_03182 2.9e-103 yabQ S spore cortex biosynthesis protein
JPCLEFIL_03183 1.9e-49 yabP S Sporulation protein YabP
JPCLEFIL_03184 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JPCLEFIL_03185 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
JPCLEFIL_03186 1.6e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JPCLEFIL_03187 6.2e-91 spoVT K stage V sporulation protein
JPCLEFIL_03188 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JPCLEFIL_03189 3.7e-40 yabK S Peptide ABC transporter permease
JPCLEFIL_03190 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JPCLEFIL_03191 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JPCLEFIL_03192 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JPCLEFIL_03193 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JPCLEFIL_03194 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
JPCLEFIL_03195 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
JPCLEFIL_03196 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JPCLEFIL_03197 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JPCLEFIL_03198 2.9e-27 sspF S DNA topological change
JPCLEFIL_03199 7.8e-39 veg S protein conserved in bacteria
JPCLEFIL_03200 8.4e-146 yabG S peptidase
JPCLEFIL_03201 6.7e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JPCLEFIL_03202 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JPCLEFIL_03203 2.9e-230 rpfB GH23 T protein conserved in bacteria
JPCLEFIL_03204 4.5e-143 tatD L hydrolase, TatD
JPCLEFIL_03205 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JPCLEFIL_03206 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
JPCLEFIL_03207 1.4e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JPCLEFIL_03208 5.2e-47 yazA L endonuclease containing a URI domain
JPCLEFIL_03209 4.2e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
JPCLEFIL_03210 7.7e-37 yabA L Involved in initiation control of chromosome replication
JPCLEFIL_03211 8.8e-145 yaaT S stage 0 sporulation protein
JPCLEFIL_03212 1.3e-182 holB 2.7.7.7 L DNA polymerase III
JPCLEFIL_03213 1.2e-71 yaaR S protein conserved in bacteria
JPCLEFIL_03214 7.5e-55 yaaQ S protein conserved in bacteria
JPCLEFIL_03215 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JPCLEFIL_03216 6.4e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
JPCLEFIL_03217 1.3e-188 yaaN P Belongs to the TelA family
JPCLEFIL_03218 9.6e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
JPCLEFIL_03219 3.8e-30 csfB S Inhibitor of sigma-G Gin
JPCLEFIL_03220 2.9e-38 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_03221 2.2e-78 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPCLEFIL_03222 2.6e-61 hxlR K transcriptional
JPCLEFIL_03223 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
JPCLEFIL_03224 1.6e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
JPCLEFIL_03225 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
JPCLEFIL_03226 1.5e-65 nin S Competence protein J (ComJ)
JPCLEFIL_03227 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPCLEFIL_03228 3.9e-48 S Protein of unknown function (DUF2680)
JPCLEFIL_03229 3.1e-72 yckC S membrane
JPCLEFIL_03230 5.1e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JPCLEFIL_03231 6.6e-226 yciC S GTPases (G3E family)
JPCLEFIL_03232 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JPCLEFIL_03233 1.1e-55 nirD 1.7.1.15 P Nitrite reductase
JPCLEFIL_03234 5.4e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JPCLEFIL_03235 2.1e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JPCLEFIL_03236 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
JPCLEFIL_03237 9.9e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JPCLEFIL_03238 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JPCLEFIL_03239 8.7e-170 ycgM E Proline dehydrogenase
JPCLEFIL_03240 8.9e-147 ycgL S Predicted nucleotidyltransferase
JPCLEFIL_03241 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
JPCLEFIL_03242 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JPCLEFIL_03243 4.8e-222 G COG0477 Permeases of the major facilitator superfamily
JPCLEFIL_03244 5.6e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
JPCLEFIL_03245 3.1e-107 tmrB S AAA domain
JPCLEFIL_03247 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JPCLEFIL_03248 1.3e-113 ycgI S Domain of unknown function (DUF1989)
JPCLEFIL_03249 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
JPCLEFIL_03250 2.2e-150 yqcI S YqcI/YcgG family
JPCLEFIL_03251 4.7e-114 ycgF E Lysine exporter protein LysE YggA
JPCLEFIL_03252 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_03253 8.1e-261 mdr EGP Major facilitator Superfamily
JPCLEFIL_03254 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JPCLEFIL_03255 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
JPCLEFIL_03256 1.5e-80 ycgB
JPCLEFIL_03257 4.9e-228 ycgA S Membrane
JPCLEFIL_03258 3.1e-209 amhX S amidohydrolase
JPCLEFIL_03259 1.5e-163 opuAC E glycine betaine
JPCLEFIL_03260 1.6e-138 opuAB P glycine betaine
JPCLEFIL_03261 3.9e-229 proV 3.6.3.32 E glycine betaine
JPCLEFIL_03262 2.6e-214 naiP P Uncharacterised MFS-type transporter YbfB
JPCLEFIL_03263 6.7e-193 yceH P Belongs to the TelA family
JPCLEFIL_03264 0.0 yceG S Putative component of 'biosynthetic module'
JPCLEFIL_03265 9.7e-138 terC P Protein of unknown function (DUF475)
JPCLEFIL_03266 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
JPCLEFIL_03267 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
JPCLEFIL_03268 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
JPCLEFIL_03269 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPCLEFIL_03270 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JPCLEFIL_03271 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JPCLEFIL_03272 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
JPCLEFIL_03273 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
JPCLEFIL_03274 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
JPCLEFIL_03275 1e-188 S response regulator aspartate phosphatase
JPCLEFIL_03276 5.8e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
JPCLEFIL_03277 1.3e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
JPCLEFIL_03278 2.9e-257 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
JPCLEFIL_03279 1.5e-175 ycdA S Domain of unknown function (DUF5105)
JPCLEFIL_03280 6.2e-171 yccK C Aldo keto reductase
JPCLEFIL_03281 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
JPCLEFIL_03282 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JPCLEFIL_03283 1.6e-194 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JPCLEFIL_03284 5.9e-100 yxaF K Transcriptional regulator
JPCLEFIL_03285 1e-241 lmrB EGP the major facilitator superfamily
JPCLEFIL_03286 5.5e-206 ycbU E Selenocysteine lyase
JPCLEFIL_03287 3.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JPCLEFIL_03288 1.3e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JPCLEFIL_03289 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JPCLEFIL_03290 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
JPCLEFIL_03291 5.3e-77 sleB 3.5.1.28 M Cell wall
JPCLEFIL_03292 5.6e-62 ycbP S Protein of unknown function (DUF2512)
JPCLEFIL_03293 1.1e-56 traF CO Thioredoxin
JPCLEFIL_03294 1.5e-62 mhqP S DoxX
JPCLEFIL_03295 2.2e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
JPCLEFIL_03296 4.5e-109 ydfN C nitroreductase
JPCLEFIL_03297 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JPCLEFIL_03298 1.2e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
JPCLEFIL_03299 1.5e-124 ycbJ S Macrolide 2'-phosphotransferase
JPCLEFIL_03300 7.4e-172 glnL T Regulator
JPCLEFIL_03301 1.8e-205 phoQ 2.7.13.3 T Histidine kinase
JPCLEFIL_03302 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
JPCLEFIL_03303 2.7e-258 agcS E Sodium alanine symporter
JPCLEFIL_03304 1.5e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
JPCLEFIL_03305 1.5e-256 mmuP E amino acid
JPCLEFIL_03306 3.6e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JPCLEFIL_03307 9.3e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JPCLEFIL_03308 2.5e-191 yceA S Belongs to the UPF0176 family
JPCLEFIL_03309 6.1e-42 ybfN
JPCLEFIL_03310 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
JPCLEFIL_03311 1.9e-86 ybfM S SNARE associated Golgi protein
JPCLEFIL_03312 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JPCLEFIL_03313 1.3e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JPCLEFIL_03314 5.4e-195 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
JPCLEFIL_03315 1.2e-82 K Helix-turn-helix XRE-family like proteins
JPCLEFIL_03316 9.2e-32
JPCLEFIL_03317 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
JPCLEFIL_03319 3.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
JPCLEFIL_03320 1e-16 S Protein of unknown function (DUF2651)
JPCLEFIL_03321 1.7e-259 glpT G -transporter
JPCLEFIL_03322 1.6e-160 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JPCLEFIL_03323 5.4e-49 M PFAM Glycosyl transferase family 2
JPCLEFIL_03324 5.5e-292 ybeC E amino acid
JPCLEFIL_03325 9.2e-40 ybyB
JPCLEFIL_03326 2.3e-106 yqeB
JPCLEFIL_03327 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
JPCLEFIL_03328 2.5e-75 S Domain of unknown function (DUF4879)
JPCLEFIL_03329 6.1e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
JPCLEFIL_03330 0.0 Q TIGRFAM amino acid adenylation domain
JPCLEFIL_03331 1.2e-102 Q Flavin containing amine oxidoreductase
JPCLEFIL_03332 0.0 Q Polyketide synthase modules and related proteins
JPCLEFIL_03333 0.0 Q Beta-ketoacyl synthase
JPCLEFIL_03334 8.7e-120 fabD 2.3.1.39 I PFAM Acyl transferase
JPCLEFIL_03335 0.0 srfAC Q TIGRFAM amino acid adenylation domain
JPCLEFIL_03336 7.8e-08
JPCLEFIL_03338 3e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JPCLEFIL_03339 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
JPCLEFIL_03340 5.5e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
JPCLEFIL_03341 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JPCLEFIL_03342 1.8e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JPCLEFIL_03343 0.0 ydiF S ABC transporter
JPCLEFIL_03344 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
JPCLEFIL_03345 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JPCLEFIL_03346 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JPCLEFIL_03347 1.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JPCLEFIL_03348 1.7e-27 ydiK S Domain of unknown function (DUF4305)
JPCLEFIL_03349 1.3e-126 ydiL S CAAX protease self-immunity
JPCLEFIL_03350 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JPCLEFIL_03351 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JPCLEFIL_03352 2.4e-122 fokIM 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
JPCLEFIL_03353 1.6e-24 L Restriction endonuclease BglII
JPCLEFIL_03354 3.3e-77 L Restriction endonuclease BglII
JPCLEFIL_03355 0.0 K NB-ARC domain
JPCLEFIL_03356 1.2e-199 gutB 1.1.1.14 E Dehydrogenase
JPCLEFIL_03357 1.9e-248 gutA G MFS/sugar transport protein
JPCLEFIL_03358 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
JPCLEFIL_03359 3.6e-30 yjdJ S Domain of unknown function (DUF4306)
JPCLEFIL_03360 2.8e-112 pspA KT Phage shock protein A
JPCLEFIL_03361 1e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JPCLEFIL_03362 3.8e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
JPCLEFIL_03363 2.4e-144 ydjI S virion core protein (lumpy skin disease virus)
JPCLEFIL_03364 0.0 yrhL I Acyltransferase family
JPCLEFIL_03365 3.1e-145 rsiV S Protein of unknown function (DUF3298)
JPCLEFIL_03366 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JPCLEFIL_03367 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
JPCLEFIL_03368 1.2e-61 ydjM M Lytic transglycolase
JPCLEFIL_03369 5.7e-133 ydjN U Involved in the tonB-independent uptake of proteins
JPCLEFIL_03371 7.2e-35 ydjO S Cold-inducible protein YdjO
JPCLEFIL_03372 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
JPCLEFIL_03373 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
JPCLEFIL_03374 5e-176 yeaC S COG0714 MoxR-like ATPases
JPCLEFIL_03375 3.3e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
JPCLEFIL_03376 0.0 yebA E COG1305 Transglutaminase-like enzymes
JPCLEFIL_03377 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JPCLEFIL_03378 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JPCLEFIL_03379 1e-249 S Domain of unknown function (DUF4179)
JPCLEFIL_03380 8.1e-209 pbuG S permease
JPCLEFIL_03381 1.5e-125 yebC M Membrane
JPCLEFIL_03383 7.5e-92 yebE S UPF0316 protein
JPCLEFIL_03384 5.5e-29 yebG S NETI protein
JPCLEFIL_03385 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JPCLEFIL_03386 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JPCLEFIL_03387 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JPCLEFIL_03388 7e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JPCLEFIL_03389 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JPCLEFIL_03390 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JPCLEFIL_03391 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JPCLEFIL_03392 1.2e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JPCLEFIL_03393 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JPCLEFIL_03394 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JPCLEFIL_03395 3.9e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JPCLEFIL_03396 2.7e-233 purD 6.3.4.13 F Belongs to the GARS family
JPCLEFIL_03397 5.7e-25 S Protein of unknown function (DUF2892)
JPCLEFIL_03398 0.0 yerA 3.5.4.2 F adenine deaminase
JPCLEFIL_03399 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
JPCLEFIL_03400 2.4e-50 yerC S protein conserved in bacteria
JPCLEFIL_03401 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
JPCLEFIL_03402 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JPCLEFIL_03403 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JPCLEFIL_03404 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JPCLEFIL_03405 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
JPCLEFIL_03406 6.1e-193 yerI S homoserine kinase type II (protein kinase fold)
JPCLEFIL_03407 1.3e-120 sapB S MgtC SapB transporter
JPCLEFIL_03408 4.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JPCLEFIL_03409 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JPCLEFIL_03410 5.7e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JPCLEFIL_03411 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JPCLEFIL_03412 1.1e-150 yerO K Transcriptional regulator
JPCLEFIL_03413 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JPCLEFIL_03414 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JPCLEFIL_03415 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JPCLEFIL_03416 4.5e-21
JPCLEFIL_03417 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
JPCLEFIL_03418 2.2e-138 cylB V ABC-2 type transporter
JPCLEFIL_03419 3.3e-37 S Protein of unknown function, DUF600
JPCLEFIL_03420 2.7e-85 S Protein of unknown function, DUF600
JPCLEFIL_03421 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
JPCLEFIL_03422 1.2e-19
JPCLEFIL_03423 9.4e-127 yeeN K transcriptional regulatory protein
JPCLEFIL_03424 9e-108 aadK G Streptomycin adenylyltransferase
JPCLEFIL_03425 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
JPCLEFIL_03426 1.3e-44 cotJB S CotJB protein
JPCLEFIL_03427 8.9e-104 cotJC P Spore Coat
JPCLEFIL_03428 5e-93 yesJ K Acetyltransferase (GNAT) family
JPCLEFIL_03430 2.1e-120 yetF S membrane
JPCLEFIL_03431 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
JPCLEFIL_03432 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JPCLEFIL_03433 3.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JPCLEFIL_03434 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
JPCLEFIL_03435 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
JPCLEFIL_03436 6.9e-105 yetJ S Belongs to the BI1 family
JPCLEFIL_03437 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_03438 3e-204 yetM CH FAD binding domain
JPCLEFIL_03439 3.4e-197 yetN S Protein of unknown function (DUF3900)
JPCLEFIL_03440 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JPCLEFIL_03441 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JPCLEFIL_03442 5.1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
JPCLEFIL_03443 2.4e-172 yfnG 4.2.1.45 M dehydratase
JPCLEFIL_03444 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
JPCLEFIL_03445 6.2e-221 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
JPCLEFIL_03446 6.9e-186 yfnD M Nucleotide-diphospho-sugar transferase
JPCLEFIL_03447 6.8e-218 fsr P COG0477 Permeases of the major facilitator superfamily
JPCLEFIL_03448 3e-246 yfnA E amino acid
JPCLEFIL_03449 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JPCLEFIL_03450 7.5e-107 yfmS NT chemotaxis protein
JPCLEFIL_03451 5.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
JPCLEFIL_03452 2.7e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JPCLEFIL_03453 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JPCLEFIL_03454 1.8e-69 yfmP K transcriptional
JPCLEFIL_03455 4e-207 yfmO EGP Major facilitator Superfamily
JPCLEFIL_03456 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JPCLEFIL_03457 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
JPCLEFIL_03458 2.1e-41 yfmK 2.3.1.128 K acetyltransferase
JPCLEFIL_03459 6.1e-188 yfmJ S N-terminal domain of oxidoreductase
JPCLEFIL_03460 2.7e-24 S Protein of unknown function (DUF3212)
JPCLEFIL_03461 1.3e-57 yflT S Heat induced stress protein YflT
JPCLEFIL_03462 1e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
JPCLEFIL_03463 6e-234 yflS P Sodium:sulfate symporter transmembrane region
JPCLEFIL_03464 5.2e-27 Q PFAM Collagen triple helix
JPCLEFIL_03465 3.4e-39 S COG NOG14552 non supervised orthologous group
JPCLEFIL_03466 3.4e-19
JPCLEFIL_03467 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
JPCLEFIL_03468 2e-74 xkdM S Phage tail tube protein
JPCLEFIL_03469 3.5e-226 xkdK S Phage tail sheath C-terminal domain
JPCLEFIL_03470 8.2e-15
JPCLEFIL_03471 3.2e-56 xkdJ
JPCLEFIL_03472 3.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
JPCLEFIL_03473 5.5e-43 yqbH S Domain of unknown function (DUF3599)
JPCLEFIL_03474 4.3e-46 yqbG S Protein of unknown function (DUF3199)
JPCLEFIL_03475 4.6e-158 xkdG S Phage capsid family
JPCLEFIL_03476 9.8e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
JPCLEFIL_03477 5.1e-241 yqbA S portal protein
JPCLEFIL_03478 8.5e-211 xtmB S phage terminase, large subunit
JPCLEFIL_03479 8.9e-110 xtmA L phage terminase small subunit
JPCLEFIL_03480 8.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
JPCLEFIL_03481 2e-10 yqaO S Phage-like element PBSX protein XtrA
JPCLEFIL_03484 3e-150 xkdC L Bacterial dnaA protein
JPCLEFIL_03486 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
JPCLEFIL_03487 2.9e-110 xkdA E IrrE N-terminal-like domain
JPCLEFIL_03489 6.7e-110 yjqB S phage-related replication protein
JPCLEFIL_03490 8e-61 yjqA S Bacterial PH domain
JPCLEFIL_03491 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JPCLEFIL_03493 1.9e-214 S response regulator aspartate phosphatase
JPCLEFIL_03494 3.1e-78 yjoA S DinB family
JPCLEFIL_03495 5.7e-130 MA20_18170 S membrane transporter protein
JPCLEFIL_03496 4.3e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
JPCLEFIL_03497 5.8e-277 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
JPCLEFIL_03498 7e-181 exuR K transcriptional
JPCLEFIL_03499 1.5e-253 yjmB G symporter YjmB
JPCLEFIL_03500 4.5e-274 uxaC 5.3.1.12 G glucuronate isomerase
JPCLEFIL_03501 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
JPCLEFIL_03502 7e-66 yjlC S Protein of unknown function (DUF1641)
JPCLEFIL_03503 1.7e-90 yjlB S Cupin domain
JPCLEFIL_03504 7.4e-175 yjlA EG Putative multidrug resistance efflux transporter
JPCLEFIL_03505 1.6e-129 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
JPCLEFIL_03506 2.1e-124 ybbM S transport system, permease component
JPCLEFIL_03507 2.6e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JPCLEFIL_03508 6.8e-29
JPCLEFIL_03509 2.2e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JPCLEFIL_03510 4.4e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
JPCLEFIL_03511 2.2e-91 yjgD S Protein of unknown function (DUF1641)
JPCLEFIL_03512 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
JPCLEFIL_03513 1.3e-99 yjgB S Domain of unknown function (DUF4309)
JPCLEFIL_03514 2.3e-66 T PhoQ Sensor
JPCLEFIL_03515 1.3e-21 yjfB S Putative motility protein
JPCLEFIL_03516 8.1e-106 yhiD S MgtC SapB transporter
JPCLEFIL_03517 1.7e-51 K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_03518 2e-34
JPCLEFIL_03519 3.9e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
JPCLEFIL_03520 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
JPCLEFIL_03521 4e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
JPCLEFIL_03522 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
JPCLEFIL_03523 1.7e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JPCLEFIL_03524 7.4e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JPCLEFIL_03525 1e-184 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JPCLEFIL_03526 8.4e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JPCLEFIL_03527 3.8e-220 ganA 3.2.1.89 G arabinogalactan
JPCLEFIL_03528 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_03529 5.5e-248 yfjF EGP Belongs to the major facilitator superfamily
JPCLEFIL_03530 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
JPCLEFIL_03531 5.7e-161 bla 3.5.2.6 V beta-lactamase
JPCLEFIL_03532 8.5e-58 E Glyoxalase-like domain
JPCLEFIL_03535 4.9e-210 yobL S Bacterial EndoU nuclease
JPCLEFIL_03536 1.5e-55
JPCLEFIL_03539 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JPCLEFIL_03540 3e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JPCLEFIL_03541 8e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
JPCLEFIL_03542 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
JPCLEFIL_03543 1.2e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPCLEFIL_03545 2.7e-35 K SpoVT / AbrB like domain
JPCLEFIL_03546 1.3e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
JPCLEFIL_03547 5.7e-124 S ABC-2 type transporter
JPCLEFIL_03548 1.4e-141 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
JPCLEFIL_03549 1.3e-35
JPCLEFIL_03550 0.0 yjcD 3.6.4.12 L DNA helicase
JPCLEFIL_03551 3.8e-38 spoVIF S Stage VI sporulation protein F
JPCLEFIL_03555 6.2e-55 yjcA S Protein of unknown function (DUF1360)
JPCLEFIL_03556 1.4e-52 cotV S Spore Coat Protein X and V domain
JPCLEFIL_03557 6.8e-21 cotW
JPCLEFIL_03558 5.1e-71 cotX S Spore Coat Protein X and V domain
JPCLEFIL_03559 4.6e-93 cotY S Spore coat protein Z
JPCLEFIL_03560 6.7e-83 cotZ S Spore coat protein
JPCLEFIL_03561 1.2e-84 yjbX S Spore coat protein
JPCLEFIL_03562 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JPCLEFIL_03563 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JPCLEFIL_03564 1.1e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JPCLEFIL_03565 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
JPCLEFIL_03566 6.7e-30 thiS H Thiamine biosynthesis
JPCLEFIL_03567 4.7e-210 thiO 1.4.3.19 E Glycine oxidase
JPCLEFIL_03568 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
JPCLEFIL_03569 4.9e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JPCLEFIL_03570 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JPCLEFIL_03571 7.5e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
JPCLEFIL_03572 1.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JPCLEFIL_03573 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JPCLEFIL_03574 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
JPCLEFIL_03575 6e-61 yjbL S Belongs to the UPF0738 family
JPCLEFIL_03576 3.1e-96 yjbK S protein conserved in bacteria
JPCLEFIL_03577 7.9e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JPCLEFIL_03578 4.8e-72 yjbI S Bacterial-like globin
JPCLEFIL_03579 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JPCLEFIL_03580 5.8e-19
JPCLEFIL_03581 0.0 pepF E oligoendopeptidase F
JPCLEFIL_03582 2.1e-216 yjbF S Competence protein
JPCLEFIL_03583 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JPCLEFIL_03584 1.1e-108 yjbE P Integral membrane protein TerC family
JPCLEFIL_03585 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JPCLEFIL_03586 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPCLEFIL_03587 1.8e-228 S Putative glycosyl hydrolase domain
JPCLEFIL_03588 2.3e-170 oppF E Belongs to the ABC transporter superfamily
JPCLEFIL_03589 2.7e-202 oppD P Belongs to the ABC transporter superfamily
JPCLEFIL_03590 8.5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPCLEFIL_03591 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPCLEFIL_03592 0.0 oppA E ABC transporter substrate-binding protein
JPCLEFIL_03593 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JPCLEFIL_03594 1.2e-145 yjbA S Belongs to the UPF0736 family
JPCLEFIL_03595 7.8e-140 EGP Transmembrane secretion effector
JPCLEFIL_03596 6.4e-86 2.1.1.265 H Tellurite resistance protein TehB
JPCLEFIL_03597 6.1e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPCLEFIL_03598 1.2e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPCLEFIL_03599 4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
JPCLEFIL_03600 3.8e-187 appF E Belongs to the ABC transporter superfamily
JPCLEFIL_03601 4.8e-182 appD P Belongs to the ABC transporter superfamily
JPCLEFIL_03602 2.8e-148 yjaZ O Zn-dependent protease
JPCLEFIL_03603 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JPCLEFIL_03604 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JPCLEFIL_03605 1e-31 yjzB
JPCLEFIL_03606 5.6e-26 comZ S ComZ
JPCLEFIL_03607 2.7e-165 med S Transcriptional activator protein med
JPCLEFIL_03608 4.4e-103 yjaV
JPCLEFIL_03609 3.2e-138 yjaU I carboxylic ester hydrolase activity
JPCLEFIL_03610 3.3e-23 yjzD S Protein of unknown function (DUF2929)
JPCLEFIL_03611 1.2e-27 yjzC S YjzC-like protein
JPCLEFIL_03612 7.8e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JPCLEFIL_03613 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
JPCLEFIL_03614 2.5e-200 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JPCLEFIL_03615 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JPCLEFIL_03616 1.1e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
JPCLEFIL_03617 1.5e-225 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JPCLEFIL_03618 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JPCLEFIL_03619 1.2e-89 norB G Major Facilitator Superfamily
JPCLEFIL_03620 1.5e-272 yitY C D-arabinono-1,4-lactone oxidase
JPCLEFIL_03621 4.6e-73 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
JPCLEFIL_03622 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
JPCLEFIL_03623 9e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
JPCLEFIL_03624 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JPCLEFIL_03625 3.5e-07
JPCLEFIL_03626 1.7e-25 S Protein of unknown function (DUF3813)
JPCLEFIL_03627 5.5e-80 ipi S Intracellular proteinase inhibitor
JPCLEFIL_03628 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
JPCLEFIL_03629 7.1e-158 yitS S protein conserved in bacteria
JPCLEFIL_03631 3.8e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
JPCLEFIL_03632 4.2e-170 yufN S ABC transporter substrate-binding protein PnrA-like
JPCLEFIL_03633 1.3e-159 cvfB S protein conserved in bacteria
JPCLEFIL_03634 6.6e-55 yajQ S Belongs to the UPF0234 family
JPCLEFIL_03635 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
JPCLEFIL_03636 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
JPCLEFIL_03637 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
JPCLEFIL_03638 1.2e-83 yisT S DinB family
JPCLEFIL_03639 5.8e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
JPCLEFIL_03640 9.2e-144 purR K helix_turn _helix lactose operon repressor
JPCLEFIL_03641 2.3e-159 yisR K Transcriptional regulator
JPCLEFIL_03642 1.5e-245 yisQ V Mate efflux family protein
JPCLEFIL_03643 1.1e-130 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
JPCLEFIL_03644 0.0 asnO 6.3.5.4 E Asparagine synthase
JPCLEFIL_03645 1e-96 yisN S Protein of unknown function (DUF2777)
JPCLEFIL_03646 3.2e-59 yisL S UPF0344 protein
JPCLEFIL_03647 7.8e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
JPCLEFIL_03648 4.8e-07 yisI S Spo0E like sporulation regulatory protein
JPCLEFIL_03649 8.4e-34 gerPA S Spore germination protein
JPCLEFIL_03650 1.8e-34 gerPB S cell differentiation
JPCLEFIL_03651 1.4e-62 gerPC S Spore germination protein
JPCLEFIL_03652 3.1e-23 gerPD S Spore germination protein
JPCLEFIL_03653 1.1e-63 gerPE S Spore germination protein GerPE
JPCLEFIL_03654 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
JPCLEFIL_03655 1.3e-50 yisB V COG1403 Restriction endonuclease
JPCLEFIL_03656 0.0 sbcC L COG0419 ATPase involved in DNA repair
JPCLEFIL_03657 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JPCLEFIL_03658 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JPCLEFIL_03659 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
JPCLEFIL_03660 2.5e-119 ydfS S Protein of unknown function (DUF421)
JPCLEFIL_03661 2.2e-93 yhjR S Rubrerythrin
JPCLEFIL_03662 5.5e-107 K QacR-like protein, C-terminal region
JPCLEFIL_03663 3e-202 blt EGP Major facilitator Superfamily
JPCLEFIL_03664 2.4e-188 abrB S membrane
JPCLEFIL_03665 1.7e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
JPCLEFIL_03666 9.2e-270 yhjG CH FAD binding domain
JPCLEFIL_03668 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
JPCLEFIL_03669 7.7e-109 yhjE S SNARE associated Golgi protein
JPCLEFIL_03670 5e-60 yhjD
JPCLEFIL_03671 3.1e-27 yhjC S Protein of unknown function (DUF3311)
JPCLEFIL_03672 6.5e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JPCLEFIL_03673 3.3e-47 S Belongs to the UPF0145 family
JPCLEFIL_03674 1.6e-42 yhjA S Excalibur calcium-binding domain
JPCLEFIL_03675 8.7e-125 yrpD S Domain of unknown function, YrpD
JPCLEFIL_03676 4.2e-62 frataxin S Domain of unknown function (DU1801)
JPCLEFIL_03677 4.7e-66 frataxin S Domain of unknown function (DU1801)
JPCLEFIL_03678 1.9e-109 comK K Competence transcription factor
JPCLEFIL_03679 5.4e-31 yhzC S IDEAL
JPCLEFIL_03680 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_03681 5.9e-296 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
JPCLEFIL_03682 3.1e-197 hemAT NT chemotaxis protein
JPCLEFIL_03683 3.5e-89 bioY S BioY family
JPCLEFIL_03684 2.3e-278 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JPCLEFIL_03685 6.7e-201 vraB 2.3.1.9 I Belongs to the thiolase family
JPCLEFIL_03686 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
JPCLEFIL_03687 7.4e-150 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
JPCLEFIL_03688 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
JPCLEFIL_03689 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
JPCLEFIL_03690 1.3e-64 yhfM
JPCLEFIL_03691 4.1e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JPCLEFIL_03692 2.7e-109 yhfK GM NmrA-like family
JPCLEFIL_03693 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
JPCLEFIL_03694 4.9e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
JPCLEFIL_03695 7.9e-11 yhfH S YhfH-like protein
JPCLEFIL_03696 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JPCLEFIL_03697 4.3e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
JPCLEFIL_03699 9.6e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JPCLEFIL_03700 1.6e-244 yhgE S YhgE Pip N-terminal domain protein
JPCLEFIL_03701 3.2e-101 yhgD K Transcriptional regulator
JPCLEFIL_03702 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JPCLEFIL_03703 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JPCLEFIL_03704 3.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JPCLEFIL_03705 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPCLEFIL_03706 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JPCLEFIL_03707 3.6e-244 yhfA C membrane
JPCLEFIL_03708 2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JPCLEFIL_03709 4e-122 ecsC S EcsC protein family
JPCLEFIL_03710 8.5e-221 ecsB U ABC transporter
JPCLEFIL_03711 1.1e-135 ecsA V transporter (ATP-binding protein)
JPCLEFIL_03712 1.2e-79 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JPCLEFIL_03713 1e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JPCLEFIL_03714 9.3e-76 trpP S Tryptophan transporter TrpP
JPCLEFIL_03715 2e-17
JPCLEFIL_03716 6.2e-39 yhaH S YtxH-like protein
JPCLEFIL_03717 8.6e-113 hpr K Negative regulator of protease production and sporulation
JPCLEFIL_03718 9.9e-55 yhaI S Protein of unknown function (DUF1878)
JPCLEFIL_03719 7e-95 yhaK S Putative zincin peptidase
JPCLEFIL_03720 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JPCLEFIL_03721 1.8e-31 yhaL S Sporulation protein YhaL
JPCLEFIL_03722 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
JPCLEFIL_03723 0.0 yhaN L AAA domain
JPCLEFIL_03724 7.2e-236 yhaO L DNA repair exonuclease
JPCLEFIL_03725 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
JPCLEFIL_03726 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
JPCLEFIL_03727 2.8e-14 S YhzD-like protein
JPCLEFIL_03728 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
JPCLEFIL_03730 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
JPCLEFIL_03731 1.4e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
JPCLEFIL_03732 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
JPCLEFIL_03733 2.7e-293 hemZ H coproporphyrinogen III oxidase
JPCLEFIL_03734 2.8e-157 yhaX S haloacid dehalogenase-like hydrolase
JPCLEFIL_03735 3.1e-201 yhaZ L DNA alkylation repair enzyme
JPCLEFIL_03736 4.4e-53 yheA S Belongs to the UPF0342 family
JPCLEFIL_03737 3.6e-205 yheB S Belongs to the UPF0754 family
JPCLEFIL_03738 3.4e-213 yheC HJ YheC/D like ATP-grasp
JPCLEFIL_03739 4.3e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
JPCLEFIL_03740 1.7e-36 yheE S Family of unknown function (DUF5342)
JPCLEFIL_03741 1.3e-28 sspB S spore protein
JPCLEFIL_03743 2.8e-111 yheG GM NAD(P)H-binding
JPCLEFIL_03744 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
JPCLEFIL_03745 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
JPCLEFIL_03747 6.2e-85 T universal stress protein
JPCLEFIL_03748 1.5e-92 ymcC S Membrane
JPCLEFIL_03749 3e-87 pksA K Transcriptional regulator
JPCLEFIL_03750 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
JPCLEFIL_03751 1.1e-155 yheN G deacetylase
JPCLEFIL_03752 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
JPCLEFIL_03753 3.5e-205 yhdY M Mechanosensitive ion channel
JPCLEFIL_03755 7.2e-127 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JPCLEFIL_03756 4.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JPCLEFIL_03757 3.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JPCLEFIL_03758 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
JPCLEFIL_03759 1.8e-234 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JPCLEFIL_03760 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
JPCLEFIL_03761 2.8e-70 cueR K transcriptional
JPCLEFIL_03762 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JPCLEFIL_03763 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JPCLEFIL_03764 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
JPCLEFIL_03765 1.3e-201 yhdL S Sigma factor regulator N-terminal
JPCLEFIL_03766 8.1e-45 yhdK S Sigma-M inhibitor protein
JPCLEFIL_03767 2.9e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JPCLEFIL_03768 1.2e-250 yhdG E amino acid
JPCLEFIL_03769 3.9e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPCLEFIL_03770 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
JPCLEFIL_03771 1.3e-162 citR K Transcriptional regulator
JPCLEFIL_03772 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JPCLEFIL_03773 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JPCLEFIL_03774 3e-270 ycgB S Stage V sporulation protein R
JPCLEFIL_03775 1.9e-254 ygxB M Conserved TM helix
JPCLEFIL_03776 1.6e-73 nsrR K Transcriptional regulator
JPCLEFIL_03777 1.1e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JPCLEFIL_03778 1.1e-53 yhdC S Protein of unknown function (DUF3889)
JPCLEFIL_03779 2.5e-39 yhdB S YhdB-like protein
JPCLEFIL_03780 2.6e-69 azr 1.7.1.6 S NADPH-dependent FMN reductase
JPCLEFIL_03781 4.3e-37 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPCLEFIL_03782 8.5e-70 yhcY 2.7.13.3 T Histidine kinase
JPCLEFIL_03783 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JPCLEFIL_03784 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JPCLEFIL_03785 1e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JPCLEFIL_03786 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
JPCLEFIL_03787 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JPCLEFIL_03788 2.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JPCLEFIL_03789 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JPCLEFIL_03790 4.2e-124 yhcW 5.4.2.6 S hydrolase
JPCLEFIL_03791 9.9e-68 yhcV S COG0517 FOG CBS domain
JPCLEFIL_03792 1.3e-69 yhcU S Family of unknown function (DUF5365)
JPCLEFIL_03793 4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JPCLEFIL_03794 2.2e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
JPCLEFIL_03795 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
JPCLEFIL_03796 8.4e-114 yhcQ M Spore coat protein
JPCLEFIL_03797 2.2e-160 yhcP
JPCLEFIL_03798 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JPCLEFIL_03799 7.2e-53 yhcM
JPCLEFIL_03800 1.1e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JPCLEFIL_03801 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
JPCLEFIL_03802 1.7e-143 metQ M Belongs to the nlpA lipoprotein family
JPCLEFIL_03803 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
JPCLEFIL_03804 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JPCLEFIL_03805 1.2e-166 yhcH V ABC transporter, ATP-binding protein
JPCLEFIL_03806 1.3e-123 yhcG V ABC transporter, ATP-binding protein
JPCLEFIL_03807 2.8e-61 yhcF K Transcriptional regulator
JPCLEFIL_03808 1.3e-52
JPCLEFIL_03809 3.8e-55 yhcC
JPCLEFIL_03810 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
JPCLEFIL_03811 8.4e-285 yhcA EGP Major facilitator Superfamily
JPCLEFIL_03812 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
JPCLEFIL_03813 4.6e-74 yhbI K DNA-binding transcription factor activity
JPCLEFIL_03814 3.9e-215 yhbH S Belongs to the UPF0229 family
JPCLEFIL_03815 0.0 prkA T Ser protein kinase
JPCLEFIL_03817 5.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
JPCLEFIL_03818 8.9e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
JPCLEFIL_03819 1.1e-107 yhbD K Protein of unknown function (DUF4004)
JPCLEFIL_03820 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JPCLEFIL_03821 1.4e-173 yhbB S Putative amidase domain
JPCLEFIL_03822 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JPCLEFIL_03823 7.2e-107 yhzB S B3/4 domain
JPCLEFIL_03825 4.8e-23 K Transcriptional regulator
JPCLEFIL_03826 8.6e-81 ygaO
JPCLEFIL_03827 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JPCLEFIL_03828 3.2e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
JPCLEFIL_03829 2.4e-142 ssuC P ABC transporter (permease)
JPCLEFIL_03830 8.5e-179 ssuA M Sulfonate ABC transporter
JPCLEFIL_03831 1.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
JPCLEFIL_03832 2.5e-180 S Amidohydrolase
JPCLEFIL_03833 2.7e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JPCLEFIL_03834 9e-133 oppF3 E Belongs to the ABC transporter superfamily
JPCLEFIL_03835 1.5e-135 oppD3 P Belongs to the ABC transporter superfamily
JPCLEFIL_03836 3.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPCLEFIL_03837 2.7e-137 appB P Binding-protein-dependent transport system inner membrane component
JPCLEFIL_03838 3.7e-230 oppA5 E PFAM extracellular solute-binding protein family 5
JPCLEFIL_03840 9e-264 ygaK C Berberine and berberine like
JPCLEFIL_03841 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JPCLEFIL_03842 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
JPCLEFIL_03843 3.6e-20 C Na+/H+ antiporter family
JPCLEFIL_03846 2.1e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
JPCLEFIL_03847 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
JPCLEFIL_03848 1.7e-75 gerD
JPCLEFIL_03849 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
JPCLEFIL_03850 4.6e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JPCLEFIL_03851 1.4e-77 ybaK S Protein of unknown function (DUF2521)
JPCLEFIL_03852 1.8e-81 yizA S Damage-inducible protein DinB
JPCLEFIL_03853 2e-143 ybaJ Q Methyltransferase domain
JPCLEFIL_03854 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
JPCLEFIL_03855 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JPCLEFIL_03856 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JPCLEFIL_03857 2.6e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPCLEFIL_03858 3.6e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPCLEFIL_03859 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPCLEFIL_03860 4.7e-58 rplQ J Ribosomal protein L17
JPCLEFIL_03861 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPCLEFIL_03862 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JPCLEFIL_03863 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JPCLEFIL_03864 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JPCLEFIL_03865 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JPCLEFIL_03866 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
JPCLEFIL_03867 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JPCLEFIL_03868 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JPCLEFIL_03869 4.1e-72 rplO J binds to the 23S rRNA
JPCLEFIL_03870 1.9e-23 rpmD J Ribosomal protein L30
JPCLEFIL_03871 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JPCLEFIL_03872 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JPCLEFIL_03873 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JPCLEFIL_03874 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JPCLEFIL_03875 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JPCLEFIL_03876 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JPCLEFIL_03877 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JPCLEFIL_03878 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JPCLEFIL_03879 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JPCLEFIL_03880 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
JPCLEFIL_03881 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JPCLEFIL_03882 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JPCLEFIL_03883 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JPCLEFIL_03884 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JPCLEFIL_03885 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JPCLEFIL_03886 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JPCLEFIL_03887 3e-105 rplD J Forms part of the polypeptide exit tunnel
JPCLEFIL_03888 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JPCLEFIL_03889 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JPCLEFIL_03890 1.2e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
JPCLEFIL_03891 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JPCLEFIL_03892 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JPCLEFIL_03893 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JPCLEFIL_03894 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JPCLEFIL_03895 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
JPCLEFIL_03896 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPCLEFIL_03897 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPCLEFIL_03898 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
JPCLEFIL_03899 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JPCLEFIL_03900 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JPCLEFIL_03901 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JPCLEFIL_03902 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JPCLEFIL_03903 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
JPCLEFIL_03904 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JPCLEFIL_03905 8.9e-116 sigH K Belongs to the sigma-70 factor family
JPCLEFIL_03906 4.2e-89 yacP S RNA-binding protein containing a PIN domain
JPCLEFIL_03907 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JPCLEFIL_03908 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JPCLEFIL_03909 5.3e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JPCLEFIL_03910 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
JPCLEFIL_03911 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JPCLEFIL_03912 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
JPCLEFIL_03913 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
JPCLEFIL_03914 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
JPCLEFIL_03915 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JPCLEFIL_03916 1.9e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JPCLEFIL_03917 0.0 clpC O Belongs to the ClpA ClpB family
JPCLEFIL_03918 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
JPCLEFIL_03919 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
JPCLEFIL_03920 7.5e-77 ctsR K Belongs to the CtsR family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)