ORF_ID e_value Gene_name EC_number CAZy COGs Description
PCGHELKP_00002 1.3e-73 2.3.1.178 M GNAT acetyltransferase
PCGHELKP_00003 3e-68 maa 2.3.1.79 S Maltose acetyltransferase
PCGHELKP_00004 5.7e-57 3.6.1.27 I Acid phosphatase homologues
PCGHELKP_00005 3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
PCGHELKP_00007 4.4e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PCGHELKP_00008 1.1e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
PCGHELKP_00009 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PCGHELKP_00010 2.5e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PCGHELKP_00011 1.4e-214 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PCGHELKP_00012 3.7e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PCGHELKP_00014 9.5e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PCGHELKP_00015 1.7e-44
PCGHELKP_00016 1.4e-120 ica2 GT2 M Glycosyl transferase family group 2
PCGHELKP_00017 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
PCGHELKP_00018 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
PCGHELKP_00019 4.9e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
PCGHELKP_00020 1e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PCGHELKP_00021 7.7e-12 M Lysin motif
PCGHELKP_00022 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PCGHELKP_00023 1.5e-83 lytH 3.5.1.28 M Ami_3
PCGHELKP_00024 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
PCGHELKP_00025 1.2e-58 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PCGHELKP_00026 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PCGHELKP_00027 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PCGHELKP_00028 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
PCGHELKP_00029 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
PCGHELKP_00030 2e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PCGHELKP_00031 1.2e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
PCGHELKP_00032 1.4e-28 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PCGHELKP_00033 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PCGHELKP_00034 1.4e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
PCGHELKP_00035 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
PCGHELKP_00036 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PCGHELKP_00037 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PCGHELKP_00039 3.7e-23 K Acetyltransferase (GNAT) domain
PCGHELKP_00040 6.2e-112 natA S Domain of unknown function (DUF4162)
PCGHELKP_00041 2.5e-84 natB CP ABC-type Na efflux pump, permease component
PCGHELKP_00042 1.8e-95 EG EamA-like transporter family
PCGHELKP_00043 7e-81 yjjH S Calcineurin-like phosphoesterase
PCGHELKP_00044 6.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PCGHELKP_00045 2.4e-40 6.3.3.2 S ASCH
PCGHELKP_00046 1.5e-69 lepB 3.4.21.89 U Signal peptidase, peptidase S26
PCGHELKP_00047 3.7e-50 degV S EDD domain protein, DegV family
PCGHELKP_00048 1.8e-51 degV S EDD domain protein, DegV family
PCGHELKP_00049 3.1e-40 K Transcriptional regulator
PCGHELKP_00050 4.2e-202 FbpA K Fibronectin-binding protein
PCGHELKP_00051 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PCGHELKP_00052 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PCGHELKP_00053 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PCGHELKP_00054 1e-39 ypaA S Protein of unknown function (DUF1304)
PCGHELKP_00056 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PCGHELKP_00057 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PCGHELKP_00058 0.0 dnaE 2.7.7.7 L DNA polymerase
PCGHELKP_00059 4.3e-15 S Protein of unknown function (DUF2929)
PCGHELKP_00060 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PCGHELKP_00061 1.6e-202 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PCGHELKP_00062 3.7e-41 XK27_04120 S Putative amino acid metabolism
PCGHELKP_00063 2.3e-159 iscS 2.8.1.7 E Aminotransferase class V
PCGHELKP_00064 1.9e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PCGHELKP_00066 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PCGHELKP_00067 7.2e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PCGHELKP_00068 1.9e-160 nhaC C Na H antiporter NhaC
PCGHELKP_00069 5.4e-127 corA P CorA-like Mg2+ transporter protein
PCGHELKP_00070 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PCGHELKP_00071 3.4e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
PCGHELKP_00072 2.8e-150 S Tetratricopeptide repeat protein
PCGHELKP_00073 4.9e-136 EG EamA-like transporter family
PCGHELKP_00074 3.9e-71 alkD L DNA alkylation repair enzyme
PCGHELKP_00075 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PCGHELKP_00076 1.9e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PCGHELKP_00077 7.8e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
PCGHELKP_00078 9.6e-149 EGP Sugar (and other) transporter
PCGHELKP_00079 7.2e-13 V PFAM secretion protein HlyD family protein
PCGHELKP_00084 1.8e-38
PCGHELKP_00085 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PCGHELKP_00086 8.1e-21 S Family of unknown function (DUF5322)
PCGHELKP_00087 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
PCGHELKP_00088 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PCGHELKP_00089 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PCGHELKP_00091 9.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PCGHELKP_00092 9.1e-172 patA 2.6.1.1 E Aminotransferase
PCGHELKP_00093 1.1e-114 glcR K DeoR C terminal sensor domain
PCGHELKP_00094 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
PCGHELKP_00095 4.7e-134 K Transcriptional regulator
PCGHELKP_00096 3.3e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PCGHELKP_00097 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PCGHELKP_00098 2.9e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PCGHELKP_00099 2.2e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PCGHELKP_00100 3.5e-204 pyrP F Permease
PCGHELKP_00101 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PCGHELKP_00102 1.6e-128 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PCGHELKP_00103 2.3e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PCGHELKP_00104 5.7e-56 3.1.3.18 J HAD-hyrolase-like
PCGHELKP_00105 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PCGHELKP_00106 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PCGHELKP_00107 6.3e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PCGHELKP_00108 4.4e-118 prmA J Ribosomal protein L11 methyltransferase
PCGHELKP_00109 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
PCGHELKP_00110 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
PCGHELKP_00111 6.4e-12
PCGHELKP_00112 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PCGHELKP_00113 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
PCGHELKP_00114 4.3e-126 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PCGHELKP_00115 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PCGHELKP_00116 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PCGHELKP_00117 9.1e-43 yodB K Transcriptional regulator, HxlR family
PCGHELKP_00118 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PCGHELKP_00119 2.2e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCGHELKP_00123 5.3e-278 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PCGHELKP_00124 1.1e-44 S Repeat protein
PCGHELKP_00125 1.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PCGHELKP_00126 2.5e-71 csm6 S Psort location Cytoplasmic, score
PCGHELKP_00127 1.2e-30 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PCGHELKP_00128 4.9e-88 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PCGHELKP_00129 4.3e-66 csm5 L RAMP superfamily
PCGHELKP_00130 2.5e-60 csm4 L CRISPR-associated RAMP protein, Csm4 family
PCGHELKP_00131 2.6e-70 csm3 L RAMP superfamily
PCGHELKP_00132 6.7e-28 csm2 L Csm2 Type III-A
PCGHELKP_00133 2.6e-207 csm1 S CRISPR-associated protein Csm1 family
PCGHELKP_00134 1.4e-37 cas6 S Pfam:DUF2276
PCGHELKP_00135 2.1e-153 M Exporter of polyketide antibiotics
PCGHELKP_00136 5.8e-205 G PTS system Galactitol-specific IIC component
PCGHELKP_00137 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PCGHELKP_00138 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PCGHELKP_00139 1.4e-84 dprA LU DNA protecting protein DprA
PCGHELKP_00140 1.1e-96 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PCGHELKP_00141 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PCGHELKP_00142 3.6e-24 yozE S Belongs to the UPF0346 family
PCGHELKP_00143 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PCGHELKP_00144 4.5e-81 ypmR E GDSL-like Lipase/Acylhydrolase
PCGHELKP_00146 2.7e-113 S Aldo keto reductase
PCGHELKP_00147 1.1e-35 K helix_turn_helix, mercury resistance
PCGHELKP_00148 7.3e-134 yvgN C Aldo keto reductase
PCGHELKP_00149 5.5e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PCGHELKP_00150 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PCGHELKP_00151 5e-276 yfmR S ABC transporter, ATP-binding protein
PCGHELKP_00152 2.5e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PCGHELKP_00153 8.2e-108 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PCGHELKP_00154 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PCGHELKP_00155 1.8e-68 xerD L Phage integrase, N-terminal SAM-like domain
PCGHELKP_00157 1.8e-56 yqeY S YqeY-like protein
PCGHELKP_00158 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PCGHELKP_00159 2.2e-116 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PCGHELKP_00162 1.2e-100 epsJ1 M Glycosyltransferase like family 2
PCGHELKP_00163 2.8e-84 M Glycosyltransferase sugar-binding region containing DXD motif
PCGHELKP_00164 8.6e-94 M transferase activity, transferring glycosyl groups
PCGHELKP_00165 1.3e-125 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PCGHELKP_00166 7.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCGHELKP_00167 6.3e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PCGHELKP_00168 7.2e-55 dnaD L DnaD domain protein
PCGHELKP_00169 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PCGHELKP_00170 9e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PCGHELKP_00171 4.2e-33 ypmB S Protein conserved in bacteria
PCGHELKP_00172 2.3e-229 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PCGHELKP_00173 4.7e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PCGHELKP_00174 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PCGHELKP_00175 6.7e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PCGHELKP_00176 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PCGHELKP_00177 8.4e-105 holA 2.7.7.7 L DNA polymerase III delta subunit
PCGHELKP_00178 1.6e-156 comEC S Competence protein ComEC
PCGHELKP_00179 2e-69 comEB 3.5.4.12 F ComE operon protein 2
PCGHELKP_00180 1.4e-50 comEA L Competence protein ComEA
PCGHELKP_00181 1.3e-267 argS 6.1.1.19 J Arginyl-tRNA synthetase
PCGHELKP_00182 4.7e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PCGHELKP_00183 2.2e-20
PCGHELKP_00185 5e-122 K LysR substrate binding domain
PCGHELKP_00186 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCGHELKP_00187 3.2e-107 S Acyltransferase family
PCGHELKP_00188 6e-161 purD 6.3.4.13 F Belongs to the GARS family
PCGHELKP_00189 5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PCGHELKP_00190 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PCGHELKP_00191 9e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PCGHELKP_00192 4.7e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PCGHELKP_00193 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCGHELKP_00194 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCGHELKP_00195 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCGHELKP_00196 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PCGHELKP_00197 2.4e-131 ylbL T Belongs to the peptidase S16 family
PCGHELKP_00198 1.5e-48 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PCGHELKP_00199 1.1e-71 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PCGHELKP_00200 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PCGHELKP_00201 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PCGHELKP_00202 3e-101 ftsW D Belongs to the SEDS family
PCGHELKP_00203 3.3e-148 manN G system, mannose fructose sorbose family IID component
PCGHELKP_00204 7e-115 manY G PTS system
PCGHELKP_00205 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PCGHELKP_00206 0.0 typA T GTP-binding protein TypA
PCGHELKP_00207 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PCGHELKP_00208 2.2e-23 yktA S Belongs to the UPF0223 family
PCGHELKP_00209 1.7e-32 1.1.1.27 C L-malate dehydrogenase activity
PCGHELKP_00210 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PCGHELKP_00211 5.5e-25
PCGHELKP_00212 2.5e-22 ykzG S Belongs to the UPF0356 family
PCGHELKP_00213 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PCGHELKP_00214 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PCGHELKP_00215 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PCGHELKP_00216 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PCGHELKP_00217 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PCGHELKP_00218 1.8e-18 S Tetratricopeptide repeat
PCGHELKP_00219 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PCGHELKP_00220 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PCGHELKP_00221 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PCGHELKP_00222 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
PCGHELKP_00223 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PCGHELKP_00224 1.3e-196 yfnA E amino acid
PCGHELKP_00225 4.4e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
PCGHELKP_00226 1.6e-113 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PCGHELKP_00227 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PCGHELKP_00228 1.1e-26 ylqC S Belongs to the UPF0109 family
PCGHELKP_00229 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PCGHELKP_00230 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PCGHELKP_00231 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PCGHELKP_00232 9.1e-149 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PCGHELKP_00233 2.7e-211 smc D Required for chromosome condensation and partitioning
PCGHELKP_00234 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PCGHELKP_00235 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCGHELKP_00236 4.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PCGHELKP_00237 6.7e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PCGHELKP_00238 2.5e-239 yloV S DAK2 domain fusion protein YloV
PCGHELKP_00239 4.5e-53 asp S Asp23 family, cell envelope-related function
PCGHELKP_00240 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PCGHELKP_00241 3.8e-93 yihY S Belongs to the UPF0761 family
PCGHELKP_00242 6.2e-12 mltD CBM50 M Lysin motif
PCGHELKP_00243 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PCGHELKP_00244 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
PCGHELKP_00245 5.1e-54 fld C Flavodoxin
PCGHELKP_00246 8.7e-53 gtcA S Teichoic acid glycosylation protein
PCGHELKP_00247 0.0 S Bacterial membrane protein YfhO
PCGHELKP_00248 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
PCGHELKP_00249 1.7e-122 S Sulfite exporter TauE/SafE
PCGHELKP_00250 2.4e-70 K Sugar-specific transcriptional regulator TrmB
PCGHELKP_00251 2.4e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PCGHELKP_00252 3.5e-182 pepS E Thermophilic metalloprotease (M29)
PCGHELKP_00253 3e-266 E Amino acid permease
PCGHELKP_00254 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PCGHELKP_00255 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PCGHELKP_00256 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
PCGHELKP_00257 4.3e-213 malT G Transporter, major facilitator family protein
PCGHELKP_00258 9.4e-101 malR K Transcriptional regulator, LacI family
PCGHELKP_00259 3.9e-279 kup P Transport of potassium into the cell
PCGHELKP_00261 1.5e-20 S Domain of unknown function (DUF3284)
PCGHELKP_00262 1.5e-159 yfmL L DEAD DEAH box helicase
PCGHELKP_00263 5.4e-128 mocA S Oxidoreductase
PCGHELKP_00264 3.4e-24 S Domain of unknown function (DUF4828)
PCGHELKP_00265 9.5e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
PCGHELKP_00266 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PCGHELKP_00267 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
PCGHELKP_00268 6.9e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
PCGHELKP_00269 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PCGHELKP_00270 2.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PCGHELKP_00271 1.4e-219 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PCGHELKP_00272 3.8e-42 O ADP-ribosylglycohydrolase
PCGHELKP_00273 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
PCGHELKP_00274 2.2e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PCGHELKP_00275 1.3e-34 K GNAT family
PCGHELKP_00276 1.7e-40
PCGHELKP_00278 1.9e-176 mgtE P Acts as a magnesium transporter
PCGHELKP_00279 6.9e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PCGHELKP_00280 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PCGHELKP_00281 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
PCGHELKP_00282 4.3e-257 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PCGHELKP_00283 3.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PCGHELKP_00284 2.2e-193 pbuX F xanthine permease
PCGHELKP_00285 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PCGHELKP_00286 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
PCGHELKP_00287 3.2e-64 S ECF transporter, substrate-specific component
PCGHELKP_00288 2.2e-126 mleP S Sodium Bile acid symporter family
PCGHELKP_00289 3.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PCGHELKP_00290 6.2e-72 mleR K LysR family
PCGHELKP_00291 1.1e-56 K transcriptional
PCGHELKP_00292 7.6e-41 K Bacterial regulatory proteins, tetR family
PCGHELKP_00293 6.1e-60 T Belongs to the universal stress protein A family
PCGHELKP_00294 1.2e-44 K Copper transport repressor CopY TcrY
PCGHELKP_00295 2.7e-10 fhaB M Rib/alpha-like repeat
PCGHELKP_00296 5.1e-42 wecD K Acetyltransferase GNAT Family
PCGHELKP_00297 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
PCGHELKP_00298 7.8e-72 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PCGHELKP_00299 2.1e-07 S SdpI/YhfL protein family
PCGHELKP_00300 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
PCGHELKP_00301 8.1e-287 pepO 3.4.24.71 O Peptidase family M13
PCGHELKP_00302 5.9e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
PCGHELKP_00303 5.3e-54 K Transcriptional regulator C-terminal region
PCGHELKP_00304 2.1e-55 jag S R3H domain protein
PCGHELKP_00305 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
PCGHELKP_00306 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
PCGHELKP_00307 5.1e-77 azlC E branched-chain amino acid
PCGHELKP_00308 9.3e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PCGHELKP_00309 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PCGHELKP_00310 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
PCGHELKP_00311 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
PCGHELKP_00312 2.4e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PCGHELKP_00313 4.1e-75 XK27_02070 S Nitroreductase family
PCGHELKP_00314 1.1e-110 endA F DNA RNA non-specific endonuclease
PCGHELKP_00316 8.5e-209 brnQ U Component of the transport system for branched-chain amino acids
PCGHELKP_00317 1.7e-61 K Bacterial regulatory proteins, tetR family
PCGHELKP_00318 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PCGHELKP_00319 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PCGHELKP_00320 1.6e-68 dhaL 2.7.1.121 S Dak2
PCGHELKP_00321 3.1e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
PCGHELKP_00322 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PCGHELKP_00323 2.4e-175 yjcE P Sodium proton antiporter
PCGHELKP_00324 1.4e-210 mtlR K Mga helix-turn-helix domain
PCGHELKP_00325 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PCGHELKP_00326 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PCGHELKP_00327 5e-37 M Glycosyl hydrolases family 25
PCGHELKP_00329 4.5e-102 tcyB E ABC transporter
PCGHELKP_00330 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCGHELKP_00331 5.7e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PCGHELKP_00332 5.5e-39 K Transcriptional regulator
PCGHELKP_00333 1.7e-107 terC P Integral membrane protein TerC family
PCGHELKP_00334 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
PCGHELKP_00335 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PCGHELKP_00336 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PCGHELKP_00337 1.1e-41 gntR1 K Transcriptional regulator, GntR family
PCGHELKP_00338 6.1e-96 V ABC transporter, ATP-binding protein
PCGHELKP_00339 2.5e-08
PCGHELKP_00340 1.1e-39 ybjQ S Belongs to the UPF0145 family
PCGHELKP_00341 3.6e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
PCGHELKP_00342 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PCGHELKP_00343 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PCGHELKP_00344 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCGHELKP_00345 1.1e-33
PCGHELKP_00346 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PCGHELKP_00347 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PCGHELKP_00348 8e-64 srtA 3.4.22.70 M sortase family
PCGHELKP_00350 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PCGHELKP_00351 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
PCGHELKP_00352 4.8e-89 pac DM Glucan-binding protein C
PCGHELKP_00355 4.5e-69
PCGHELKP_00356 6.1e-43 L Protein of unknown function (DUF3991)
PCGHELKP_00357 3.2e-165 topA2 5.99.1.2 G Topoisomerase IA
PCGHELKP_00360 2.9e-148 clpB O Belongs to the ClpA ClpB family
PCGHELKP_00364 2e-220 U TraM recognition site of TraD and TraG
PCGHELKP_00365 3.4e-77
PCGHELKP_00367 3.5e-27
PCGHELKP_00368 3.8e-191 U type IV secretory pathway VirB4
PCGHELKP_00370 1.5e-29 M CHAP domain
PCGHELKP_00373 5e-07
PCGHELKP_00374 1.4e-60 sip L Belongs to the 'phage' integrase family
PCGHELKP_00375 1.9e-29
PCGHELKP_00376 2.9e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PCGHELKP_00377 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PCGHELKP_00378 1.2e-80 yvfR V ABC transporter
PCGHELKP_00379 1.6e-52 yvfS V ABC-2 type transporter
PCGHELKP_00380 1.9e-57 salK 2.7.13.3 T Histidine kinase
PCGHELKP_00381 4.4e-77 desR K helix_turn_helix, Lux Regulon
PCGHELKP_00382 1.3e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
PCGHELKP_00383 2.1e-105 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PCGHELKP_00386 3.7e-14 S YjcQ protein
PCGHELKP_00388 1.8e-36
PCGHELKP_00389 2e-10
PCGHELKP_00390 1.4e-142 xerS L Phage integrase family
PCGHELKP_00391 2.9e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PCGHELKP_00392 1.4e-137 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PCGHELKP_00393 4.7e-217 1.3.5.4 C FAD binding domain
PCGHELKP_00394 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
PCGHELKP_00395 3.6e-138 G Xylose isomerase-like TIM barrel
PCGHELKP_00396 1.7e-72 K Transcriptional regulator, LysR family
PCGHELKP_00397 8.2e-99 EGP Major Facilitator Superfamily
PCGHELKP_00398 2.6e-129 EGP Major Facilitator Superfamily
PCGHELKP_00399 7e-70 L Integrase core domain
PCGHELKP_00401 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
PCGHELKP_00402 4.8e-32 P Heavy-metal-associated domain
PCGHELKP_00404 3.2e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PCGHELKP_00405 2.7e-117 K Primase C terminal 1 (PriCT-1)
PCGHELKP_00407 2.8e-12 S Thioredoxin
PCGHELKP_00409 5.7e-07 L Integrase core domain
PCGHELKP_00410 3.2e-40
PCGHELKP_00415 1.9e-08 2.3.1.19 K Cro/C1-type HTH DNA-binding domain
PCGHELKP_00421 2.6e-16 S RelB antitoxin
PCGHELKP_00423 1.8e-26
PCGHELKP_00427 2.9e-61 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PCGHELKP_00428 1.1e-13
PCGHELKP_00429 1.1e-13
PCGHELKP_00431 9.3e-16
PCGHELKP_00443 1.6e-20 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
PCGHELKP_00445 5.1e-16
PCGHELKP_00446 5.9e-141 ruvB 3.6.4.12 L four-way junction helicase activity
PCGHELKP_00451 3.2e-73
PCGHELKP_00453 1.1e-202 traI 5.99.1.2 L C-terminal repeat of topoisomerase
PCGHELKP_00455 3.1e-193 clpB O Belongs to the ClpA ClpB family
PCGHELKP_00458 4.1e-11
PCGHELKP_00459 5e-257 U COG3505 Type IV secretory pathway, VirD4 components
PCGHELKP_00460 1.1e-81
PCGHELKP_00461 2.7e-07 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
PCGHELKP_00464 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PCGHELKP_00465 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PCGHELKP_00466 3.8e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
PCGHELKP_00467 1.2e-180 pbuG S permease
PCGHELKP_00469 1.6e-79 S Cell surface protein
PCGHELKP_00471 1.2e-255 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
PCGHELKP_00472 2.2e-61
PCGHELKP_00473 1.4e-40 rpmE2 J Ribosomal protein L31
PCGHELKP_00474 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PCGHELKP_00475 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PCGHELKP_00477 1.6e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PCGHELKP_00478 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PCGHELKP_00479 6.3e-33 ywiB S Domain of unknown function (DUF1934)
PCGHELKP_00480 9.8e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
PCGHELKP_00481 8.6e-206 ywfO S HD domain protein
PCGHELKP_00482 4.4e-88 S hydrolase
PCGHELKP_00483 7.7e-105 ydcZ S Putative inner membrane exporter, YdcZ
PCGHELKP_00484 2.2e-27
PCGHELKP_00485 7e-73
PCGHELKP_00487 5.4e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
PCGHELKP_00488 1.9e-21
PCGHELKP_00489 6.7e-56 spoVK O ATPase family associated with various cellular activities (AAA)
PCGHELKP_00491 1.7e-86 S overlaps another CDS with the same product name
PCGHELKP_00492 1e-124 S overlaps another CDS with the same product name
PCGHELKP_00493 2.2e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PCGHELKP_00494 3.9e-63 bCE_4747 S Beta-lactamase superfamily domain
PCGHELKP_00495 3.9e-290 ybiT S ABC transporter, ATP-binding protein
PCGHELKP_00496 5.1e-78 2.4.2.3 F Phosphorylase superfamily
PCGHELKP_00497 1.7e-24
PCGHELKP_00498 1.2e-112 dkg S reductase
PCGHELKP_00500 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PCGHELKP_00501 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCGHELKP_00502 1.7e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PCGHELKP_00503 1.9e-47 EGP Transmembrane secretion effector
PCGHELKP_00504 5.2e-137 purR 2.4.2.7 F pur operon repressor
PCGHELKP_00505 1.1e-52 adhR K helix_turn_helix, mercury resistance
PCGHELKP_00506 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PCGHELKP_00507 9.3e-19 M domain protein
PCGHELKP_00508 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PCGHELKP_00509 2.3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
PCGHELKP_00510 6e-32 S Phage minor capsid protein 2
PCGHELKP_00513 1.6e-49 M Phage tail tape measure protein TP901
PCGHELKP_00514 4e-110 IQ NAD dependent epimerase/dehydratase family
PCGHELKP_00515 2.2e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
PCGHELKP_00516 4.5e-43 gutM K Glucitol operon activator protein (GutM)
PCGHELKP_00517 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
PCGHELKP_00518 1.2e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
PCGHELKP_00519 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PCGHELKP_00520 1.3e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
PCGHELKP_00521 9.3e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PCGHELKP_00522 2.5e-136 pfoS S Phosphotransferase system, EIIC
PCGHELKP_00523 2.9e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
PCGHELKP_00524 1.2e-56 hsdM 2.1.1.72 V HsdM N-terminal domain
PCGHELKP_00525 4.1e-249 2.1.1.72 V type I restriction-modification system
PCGHELKP_00526 1e-50 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PCGHELKP_00527 9.7e-127 xerC L Belongs to the 'phage' integrase family
PCGHELKP_00528 3.2e-43 3.1.21.3 V type i restriction
PCGHELKP_00529 3.8e-50 3.1.21.3 V Type I restriction modification DNA specificity domain
PCGHELKP_00531 6.6e-54
PCGHELKP_00532 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PCGHELKP_00533 3.2e-27 K Helix-turn-helix XRE-family like proteins
PCGHELKP_00534 8.5e-138 yfeO P Voltage gated chloride channel
PCGHELKP_00535 2e-225 E ABC transporter, substratebinding protein
PCGHELKP_00536 3.1e-115 sufC O FeS assembly ATPase SufC
PCGHELKP_00537 4.6e-145 sufD O FeS assembly protein SufD
PCGHELKP_00538 1.8e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PCGHELKP_00539 1.4e-40 nifU C SUF system FeS assembly protein, NifU family
PCGHELKP_00540 1.2e-239 sufB O assembly protein SufB
PCGHELKP_00541 5.6e-45 S VIT family
PCGHELKP_00542 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PCGHELKP_00543 4.4e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCGHELKP_00544 1e-111 rssA S Phospholipase, patatin family
PCGHELKP_00545 1.1e-15
PCGHELKP_00547 2.5e-39
PCGHELKP_00548 4.6e-15 fhaB M Membrane
PCGHELKP_00549 2.2e-90 tuaB S Polysaccharide biosynthesis protein
PCGHELKP_00550 1e-66 ppm1 GT2 M Glycosyl transferase family 2
PCGHELKP_00551 5.1e-15 wzy S EpsG family
PCGHELKP_00552 1.1e-31 M Glycosyl transferases group 1
PCGHELKP_00553 3.1e-19 2.3.1.18 S Psort location Cytoplasmic, score 9.26
PCGHELKP_00554 3.3e-99 S Glycosyltransferase WbsX
PCGHELKP_00555 5e-43 cps M Glycosyltransferase family 92
PCGHELKP_00556 2.2e-67 rgpB M Glycosyl transferase family 2
PCGHELKP_00557 2e-142 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PCGHELKP_00558 1.7e-84 wbbL S Glycosyl transferase family 2
PCGHELKP_00559 2.8e-71 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
PCGHELKP_00560 1.1e-26 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
PCGHELKP_00561 3.4e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PCGHELKP_00562 5.6e-165 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PCGHELKP_00563 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PCGHELKP_00564 4.2e-145 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PCGHELKP_00565 1.7e-72 S Glycosyltransferase like family 2
PCGHELKP_00566 4.5e-84 S Psort location CytoplasmicMembrane, score
PCGHELKP_00567 5.4e-99 waaB GT4 M Glycosyl transferases group 1
PCGHELKP_00568 4.6e-89 S Psort location CytoplasmicMembrane, score
PCGHELKP_00569 1.1e-61 S Glycosyltransferase like family 2
PCGHELKP_00570 4.9e-116 cps1D M Domain of unknown function (DUF4422)
PCGHELKP_00571 3e-39 S CAAX protease self-immunity
PCGHELKP_00572 9.1e-89 yvyE 3.4.13.9 S YigZ family
PCGHELKP_00573 2.9e-58 S Haloacid dehalogenase-like hydrolase
PCGHELKP_00574 2.9e-153 EGP Major facilitator Superfamily
PCGHELKP_00576 9e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PCGHELKP_00577 1.2e-27 yraB K transcriptional regulator
PCGHELKP_00578 9.8e-90 S NADPH-dependent FMN reductase
PCGHELKP_00579 2.3e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PCGHELKP_00580 1.5e-55 S ECF transporter, substrate-specific component
PCGHELKP_00581 2.5e-96 znuB U ABC 3 transport family
PCGHELKP_00582 1e-98 fhuC P ABC transporter
PCGHELKP_00583 1.3e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
PCGHELKP_00584 2e-38
PCGHELKP_00585 1.4e-53 XK27_01040 S Protein of unknown function (DUF1129)
PCGHELKP_00586 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PCGHELKP_00587 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
PCGHELKP_00588 6.3e-109 spo0J K Belongs to the ParB family
PCGHELKP_00589 6.5e-118 soj D Sporulation initiation inhibitor
PCGHELKP_00590 1.7e-82 noc K Belongs to the ParB family
PCGHELKP_00591 6.2e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PCGHELKP_00592 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PCGHELKP_00593 1.4e-109 3.1.4.46 C phosphodiesterase
PCGHELKP_00594 0.0 pacL 3.6.3.8 P P-type ATPase
PCGHELKP_00595 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PCGHELKP_00596 1.6e-242 lysP E amino acid
PCGHELKP_00597 1.2e-68 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
PCGHELKP_00598 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PCGHELKP_00599 9.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PCGHELKP_00600 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
PCGHELKP_00601 7.6e-83 lysR5 K LysR substrate binding domain
PCGHELKP_00602 2.2e-119 yxaA S membrane transporter protein
PCGHELKP_00603 2.6e-32 ywjH S Protein of unknown function (DUF1634)
PCGHELKP_00604 3.2e-118 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PCGHELKP_00605 6e-226 pipD E Dipeptidase
PCGHELKP_00606 1.8e-21 K helix_turn_helix multiple antibiotic resistance protein
PCGHELKP_00607 1.5e-165 EGP Major facilitator Superfamily
PCGHELKP_00608 4.7e-81 S L,D-transpeptidase catalytic domain
PCGHELKP_00609 9.6e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PCGHELKP_00610 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PCGHELKP_00611 7.5e-27 ydiI Q Thioesterase superfamily
PCGHELKP_00612 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
PCGHELKP_00613 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PCGHELKP_00614 6.4e-114 degV S EDD domain protein, DegV family
PCGHELKP_00615 1e-225 cadA P P-type ATPase
PCGHELKP_00616 2.4e-254 E Amino acid permease
PCGHELKP_00617 2.7e-83 S Membrane
PCGHELKP_00618 7e-50 cps3F
PCGHELKP_00619 2.1e-282 fruA 2.7.1.202 GT Phosphotransferase System
PCGHELKP_00620 9.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PCGHELKP_00621 4.5e-87 fruR K DeoR C terminal sensor domain
PCGHELKP_00622 1.4e-219 XK27_08635 S UPF0210 protein
PCGHELKP_00623 9.2e-27 gcvR T Belongs to the UPF0237 family
PCGHELKP_00624 1.8e-38
PCGHELKP_00625 1.3e-77 E GDSL-like Lipase/Acylhydrolase family
PCGHELKP_00626 9.2e-56 S Protein of unknown function (DUF975)
PCGHELKP_00627 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
PCGHELKP_00628 4e-230 lpdA 1.8.1.4 C Dehydrogenase
PCGHELKP_00629 4.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PCGHELKP_00630 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PCGHELKP_00631 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PCGHELKP_00632 2e-23 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
PCGHELKP_00633 1e-119 sip L Belongs to the 'phage' integrase family
PCGHELKP_00634 2.1e-15 K Transcriptional regulator, Cro CI family
PCGHELKP_00635 1.5e-07 K Helix-turn-helix XRE-family like proteins
PCGHELKP_00636 6.2e-45 S Phage regulatory protein Rha (Phage_pRha)
PCGHELKP_00641 5.7e-20
PCGHELKP_00643 1.5e-37 ybl78 L Conserved phage C-terminus (Phg_2220_C)
PCGHELKP_00644 3.7e-09 arpU S Phage transcriptional regulator, ArpU family
PCGHELKP_00645 2.3e-16
PCGHELKP_00646 8.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCGHELKP_00647 2.6e-97 ygaC J Belongs to the UPF0374 family
PCGHELKP_00648 6.9e-92 yueF S AI-2E family transporter
PCGHELKP_00649 3.2e-157 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PCGHELKP_00650 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PCGHELKP_00651 1.5e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PCGHELKP_00652 0.0 lacL 3.2.1.23 G -beta-galactosidase
PCGHELKP_00653 7.5e-288 lacS G Transporter
PCGHELKP_00654 5.9e-111 galR K Transcriptional regulator
PCGHELKP_00655 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PCGHELKP_00656 8.6e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PCGHELKP_00657 1.2e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PCGHELKP_00658 3e-311 rafA 3.2.1.22 G alpha-galactosidase
PCGHELKP_00659 1.7e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PCGHELKP_00660 1.5e-22 XK27_09445 S Domain of unknown function (DUF1827)
PCGHELKP_00661 0.0 clpE O Belongs to the ClpA ClpB family
PCGHELKP_00662 1.5e-15
PCGHELKP_00663 9.7e-37 ptsH G phosphocarrier protein HPR
PCGHELKP_00664 6.9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PCGHELKP_00665 2e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PCGHELKP_00666 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
PCGHELKP_00667 5.2e-131 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PCGHELKP_00668 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
PCGHELKP_00669 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PCGHELKP_00670 2e-80 yitS S EDD domain protein, DegV family
PCGHELKP_00671 5.6e-57 racA K Domain of unknown function (DUF1836)
PCGHELKP_00672 5.2e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PCGHELKP_00673 4.3e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PCGHELKP_00674 3.6e-167 potE2 E amino acid
PCGHELKP_00677 3.5e-19
PCGHELKP_00678 2.7e-94 pstS P T5orf172
PCGHELKP_00679 1.4e-257 yeeB L DEAD-like helicases superfamily
PCGHELKP_00680 4.3e-236 yeeA V Type II restriction enzyme, methylase subunits
PCGHELKP_00681 3e-57 yeeA V Type II restriction enzyme, methylase subunits
PCGHELKP_00682 7.9e-66
PCGHELKP_00683 1.5e-62
PCGHELKP_00684 3.2e-161 L T/G mismatch-specific endonuclease activity
PCGHELKP_00686 6e-61 hsdM 2.1.1.72 V HsdM N-terminal domain
PCGHELKP_00687 1.3e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
PCGHELKP_00688 2.4e-106 L Belongs to the 'phage' integrase family
PCGHELKP_00690 1.2e-191 XK27_11280 S Psort location CytoplasmicMembrane, score
PCGHELKP_00692 1.3e-108 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PCGHELKP_00693 4.8e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
PCGHELKP_00694 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
PCGHELKP_00695 2.6e-216 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PCGHELKP_00696 1.5e-188 iolF EGP Major facilitator Superfamily
PCGHELKP_00697 3.1e-75 rhaR K helix_turn_helix, arabinose operon control protein
PCGHELKP_00698 4.9e-50 S Membrane
PCGHELKP_00699 1.3e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PCGHELKP_00700 4.7e-54 S COG NOG19168 non supervised orthologous group
PCGHELKP_00702 5.1e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
PCGHELKP_00704 1.2e-216 pts36C G PTS system sugar-specific permease component
PCGHELKP_00705 6.9e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PCGHELKP_00706 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PCGHELKP_00707 1.1e-69 K DeoR C terminal sensor domain
PCGHELKP_00708 6.1e-125 yvgN C Aldo keto reductase
PCGHELKP_00711 1.3e-73 draG O ADP-ribosylglycohydrolase
PCGHELKP_00712 5.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PCGHELKP_00713 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PCGHELKP_00714 1.9e-61 divIVA D DivIVA domain protein
PCGHELKP_00715 3.5e-82 ylmH S S4 domain protein
PCGHELKP_00716 3e-19 yggT S YGGT family
PCGHELKP_00717 2.5e-32 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PCGHELKP_00718 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PCGHELKP_00719 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PCGHELKP_00720 2.2e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PCGHELKP_00721 8.9e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PCGHELKP_00722 4.5e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PCGHELKP_00723 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PCGHELKP_00724 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
PCGHELKP_00725 2.5e-11 ftsL D cell division protein FtsL
PCGHELKP_00726 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PCGHELKP_00727 1.5e-55 mraZ K Belongs to the MraZ family
PCGHELKP_00729 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
PCGHELKP_00731 9.8e-100 D Alpha beta
PCGHELKP_00732 3.7e-109 aatB ET ABC transporter substrate-binding protein
PCGHELKP_00733 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCGHELKP_00734 1.9e-94 glnP P ABC transporter permease
PCGHELKP_00735 1.8e-126 minD D Belongs to the ParA family
PCGHELKP_00736 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PCGHELKP_00737 1.5e-54 mreD M rod shape-determining protein MreD
PCGHELKP_00738 2.1e-88 mreC M Involved in formation and maintenance of cell shape
PCGHELKP_00739 3.6e-156 mreB D cell shape determining protein MreB
PCGHELKP_00740 4.5e-21 K Cold shock
PCGHELKP_00741 6.2e-80 radC L DNA repair protein
PCGHELKP_00742 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PCGHELKP_00743 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PCGHELKP_00744 3.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCGHELKP_00745 3.8e-162 iscS2 2.8.1.7 E Aminotransferase class V
PCGHELKP_00746 4.4e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PCGHELKP_00747 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
PCGHELKP_00748 6.3e-100 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PCGHELKP_00749 2e-24 yueI S Protein of unknown function (DUF1694)
PCGHELKP_00750 5.2e-189 rarA L recombination factor protein RarA
PCGHELKP_00752 3.2e-73 usp6 T universal stress protein
PCGHELKP_00753 3.8e-54 tag 3.2.2.20 L glycosylase
PCGHELKP_00754 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PCGHELKP_00755 3.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PCGHELKP_00758 1.5e-75 yviA S Protein of unknown function (DUF421)
PCGHELKP_00759 1.8e-27 S Protein of unknown function (DUF3290)
PCGHELKP_00760 2.3e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
PCGHELKP_00761 3.5e-296 S membrane
PCGHELKP_00762 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PCGHELKP_00763 3.1e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
PCGHELKP_00764 5.8e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
PCGHELKP_00765 2.6e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PCGHELKP_00767 1.4e-16
PCGHELKP_00768 5.6e-200 oatA I Acyltransferase
PCGHELKP_00769 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PCGHELKP_00770 1.9e-306 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PCGHELKP_00771 2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCGHELKP_00774 1.5e-41 S Phosphoesterase
PCGHELKP_00775 5e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PCGHELKP_00776 1.1e-60 yslB S Protein of unknown function (DUF2507)
PCGHELKP_00777 9.9e-41 trxA O Belongs to the thioredoxin family
PCGHELKP_00778 2.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PCGHELKP_00779 1.2e-17 cvpA S Colicin V production protein
PCGHELKP_00780 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PCGHELKP_00781 1.9e-33 yrzB S Belongs to the UPF0473 family
PCGHELKP_00782 5.2e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PCGHELKP_00783 2.1e-36 yrzL S Belongs to the UPF0297 family
PCGHELKP_00784 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PCGHELKP_00785 5.1e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PCGHELKP_00786 1.6e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PCGHELKP_00787 7.5e-13
PCGHELKP_00788 8e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PCGHELKP_00789 3.2e-66 yrjD S LUD domain
PCGHELKP_00790 1.1e-244 lutB C 4Fe-4S dicluster domain
PCGHELKP_00791 6.9e-117 lutA C Cysteine-rich domain
PCGHELKP_00792 2e-208 yfnA E Amino Acid
PCGHELKP_00794 4.3e-61 uspA T universal stress protein
PCGHELKP_00796 1.8e-12 yajC U Preprotein translocase
PCGHELKP_00797 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PCGHELKP_00798 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PCGHELKP_00799 2.8e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PCGHELKP_00800 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PCGHELKP_00801 8.4e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PCGHELKP_00802 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PCGHELKP_00803 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
PCGHELKP_00804 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PCGHELKP_00805 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PCGHELKP_00806 1.5e-63 ymfM S Helix-turn-helix domain
PCGHELKP_00807 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
PCGHELKP_00808 8.4e-150 ymfH S Peptidase M16
PCGHELKP_00809 5.3e-109 ymfF S Peptidase M16 inactive domain protein
PCGHELKP_00810 4.5e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
PCGHELKP_00811 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PCGHELKP_00812 7.5e-99 rrmA 2.1.1.187 H Methyltransferase
PCGHELKP_00813 6.4e-61 ybaK J Aminoacyl-tRNA editing domain
PCGHELKP_00814 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PCGHELKP_00815 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PCGHELKP_00816 4.2e-21 cutC P Participates in the control of copper homeostasis
PCGHELKP_00817 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PCGHELKP_00818 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PCGHELKP_00819 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PCGHELKP_00820 5.3e-68 ybbR S YbbR-like protein
PCGHELKP_00821 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PCGHELKP_00822 2.4e-71 S Protein of unknown function (DUF1361)
PCGHELKP_00823 1.2e-115 murB 1.3.1.98 M Cell wall formation
PCGHELKP_00824 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
PCGHELKP_00825 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PCGHELKP_00826 1.3e-142 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PCGHELKP_00827 6.8e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PCGHELKP_00828 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
PCGHELKP_00829 3.1e-42 yxjI
PCGHELKP_00830 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PCGHELKP_00831 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PCGHELKP_00832 2.8e-19 secG U Preprotein translocase
PCGHELKP_00833 9.2e-180 clcA P chloride
PCGHELKP_00834 6.7e-146 lmrP E Major Facilitator Superfamily
PCGHELKP_00835 1.8e-169 T PhoQ Sensor
PCGHELKP_00836 5e-104 K response regulator
PCGHELKP_00837 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PCGHELKP_00838 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PCGHELKP_00839 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PCGHELKP_00840 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PCGHELKP_00841 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PCGHELKP_00842 2.9e-137 cggR K Putative sugar-binding domain
PCGHELKP_00844 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PCGHELKP_00845 1.8e-149 whiA K May be required for sporulation
PCGHELKP_00846 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PCGHELKP_00847 7.5e-126 rapZ S Displays ATPase and GTPase activities
PCGHELKP_00848 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
PCGHELKP_00849 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PCGHELKP_00850 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PCGHELKP_00851 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PCGHELKP_00852 1.4e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PCGHELKP_00853 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PCGHELKP_00854 2.5e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PCGHELKP_00855 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PCGHELKP_00856 4.1e-08 KT PspC domain protein
PCGHELKP_00857 1.2e-85 phoR 2.7.13.3 T Histidine kinase
PCGHELKP_00858 6e-86 K response regulator
PCGHELKP_00859 4.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
PCGHELKP_00860 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PCGHELKP_00861 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PCGHELKP_00862 3.1e-95 yeaN P Major Facilitator Superfamily
PCGHELKP_00863 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PCGHELKP_00864 1e-45 comFC S Competence protein
PCGHELKP_00865 5.4e-128 comFA L Helicase C-terminal domain protein
PCGHELKP_00866 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
PCGHELKP_00867 4.1e-296 ydaO E amino acid
PCGHELKP_00868 3.3e-269 aha1 P COG COG0474 Cation transport ATPase
PCGHELKP_00869 1.8e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PCGHELKP_00870 1.8e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PCGHELKP_00871 2.4e-33 S CAAX protease self-immunity
PCGHELKP_00872 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PCGHELKP_00873 1.2e-253 uup S ABC transporter, ATP-binding protein
PCGHELKP_00874 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PCGHELKP_00875 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PCGHELKP_00876 2.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PCGHELKP_00877 2.7e-140 ansA 3.5.1.1 EJ Asparaginase
PCGHELKP_00878 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
PCGHELKP_00879 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PCGHELKP_00880 1.4e-40 yabA L Involved in initiation control of chromosome replication
PCGHELKP_00881 1e-83 holB 2.7.7.7 L DNA polymerase III
PCGHELKP_00882 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PCGHELKP_00883 9.2e-29 yaaL S Protein of unknown function (DUF2508)
PCGHELKP_00884 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PCGHELKP_00885 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PCGHELKP_00886 1.5e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCGHELKP_00887 4.8e-61 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PCGHELKP_00888 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
PCGHELKP_00889 1.2e-27 nrdH O Glutaredoxin
PCGHELKP_00890 4.8e-45 nrdI F NrdI Flavodoxin like
PCGHELKP_00891 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCGHELKP_00892 1.4e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCGHELKP_00893 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PCGHELKP_00894 1.4e-54
PCGHELKP_00895 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PCGHELKP_00896 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PCGHELKP_00897 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PCGHELKP_00898 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PCGHELKP_00899 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
PCGHELKP_00900 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PCGHELKP_00901 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PCGHELKP_00902 7e-71 yacP S YacP-like NYN domain
PCGHELKP_00903 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCGHELKP_00904 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PCGHELKP_00905 1.8e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PCGHELKP_00906 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PCGHELKP_00907 8.2e-154 yacL S domain protein
PCGHELKP_00908 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PCGHELKP_00909 3.1e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PCGHELKP_00910 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
PCGHELKP_00911 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
PCGHELKP_00912 1.4e-33 S Enterocin A Immunity
PCGHELKP_00913 8.3e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PCGHELKP_00914 4.5e-129 mleP2 S Sodium Bile acid symporter family
PCGHELKP_00915 3.5e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PCGHELKP_00917 2.3e-43 ydcK S Belongs to the SprT family
PCGHELKP_00918 3.3e-252 yhgF K Tex-like protein N-terminal domain protein
PCGHELKP_00919 6.8e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PCGHELKP_00920 1.6e-242 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PCGHELKP_00921 1.2e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PCGHELKP_00922 6.4e-96 gntR1 K UbiC transcription regulator-associated domain protein
PCGHELKP_00923 1.2e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PCGHELKP_00927 5.1e-08
PCGHELKP_00928 1.1e-07
PCGHELKP_00929 1.6e-197 dtpT U amino acid peptide transporter
PCGHELKP_00930 2.7e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PCGHELKP_00931 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PCGHELKP_00932 8.1e-182 gatC G PTS system sugar-specific permease component
PCGHELKP_00933 1.2e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
PCGHELKP_00934 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
PCGHELKP_00935 6e-88 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PCGHELKP_00936 2.1e-277 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PCGHELKP_00937 2e-232 tetP J elongation factor G
PCGHELKP_00938 1.9e-25 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PCGHELKP_00940 7e-217 yjeM E Amino Acid
PCGHELKP_00941 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
PCGHELKP_00942 4.3e-75 K Helix-turn-helix domain, rpiR family
PCGHELKP_00943 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PCGHELKP_00944 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PCGHELKP_00945 6.5e-90 nanK GK ROK family
PCGHELKP_00946 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
PCGHELKP_00947 6.1e-65 G Xylose isomerase domain protein TIM barrel
PCGHELKP_00948 7.9e-155 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PCGHELKP_00949 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PCGHELKP_00950 1.6e-72 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PCGHELKP_00951 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PCGHELKP_00952 7.7e-41 S Iron-sulfur cluster assembly protein
PCGHELKP_00953 1.3e-66 S Protein of unknown function (DUF1440)
PCGHELKP_00954 7.7e-82 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PCGHELKP_00955 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
PCGHELKP_00958 7.2e-08
PCGHELKP_00959 1.9e-13
PCGHELKP_00962 7.5e-58 2.7.13.3 T GHKL domain
PCGHELKP_00963 1.9e-56 K LytTr DNA-binding domain
PCGHELKP_00969 1.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
PCGHELKP_00970 2.2e-266 fbp 3.1.3.11 G phosphatase activity
PCGHELKP_00971 8.8e-50 yugI 5.3.1.9 J general stress protein
PCGHELKP_00972 3.8e-97 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PCGHELKP_00973 3e-92 dedA S SNARE associated Golgi protein
PCGHELKP_00974 6e-32 S Protein of unknown function (DUF1461)
PCGHELKP_00975 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PCGHELKP_00976 1.9e-53 yutD S Protein of unknown function (DUF1027)
PCGHELKP_00977 3e-57 S Calcineurin-like phosphoesterase
PCGHELKP_00978 9.3e-184 cycA E Amino acid permease
PCGHELKP_00979 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
PCGHELKP_00981 9.4e-11 S Putative Competence protein ComGF
PCGHELKP_00983 1.1e-13
PCGHELKP_00984 3.6e-27 comGC U competence protein ComGC
PCGHELKP_00985 1.3e-97 comGB NU type II secretion system
PCGHELKP_00986 1.1e-120 comGA NU Type II IV secretion system protein
PCGHELKP_00987 1.8e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PCGHELKP_00988 1.5e-119 yebC K Transcriptional regulatory protein
PCGHELKP_00989 3.7e-42 S VanZ like family
PCGHELKP_00990 3.4e-159 ccpA K catabolite control protein A
PCGHELKP_00991 7.8e-173 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PCGHELKP_00992 3e-14
PCGHELKP_00995 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PCGHELKP_00996 6.9e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
PCGHELKP_00997 2.3e-65 hly S protein, hemolysin III
PCGHELKP_00998 1.6e-40 M1-874 K Domain of unknown function (DUF1836)
PCGHELKP_00999 9.4e-84 S membrane
PCGHELKP_01000 1.1e-79 S VIT family
PCGHELKP_01001 5.2e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PCGHELKP_01002 2.7e-56 P Plays a role in the regulation of phosphate uptake
PCGHELKP_01003 6.1e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PCGHELKP_01004 1e-113 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PCGHELKP_01005 5.1e-122 pstA P Phosphate transport system permease protein PstA
PCGHELKP_01006 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
PCGHELKP_01007 1.1e-97 pstS P Phosphate
PCGHELKP_01008 1.3e-41 yjbH Q Thioredoxin
PCGHELKP_01009 2.5e-232 pepF E oligoendopeptidase F
PCGHELKP_01010 9.5e-68 coiA 3.6.4.12 S Competence protein
PCGHELKP_01011 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PCGHELKP_01012 6.3e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PCGHELKP_01013 9.4e-214 yjeM E Amino Acid
PCGHELKP_01014 5.6e-190 glnPH2 P ABC transporter permease
PCGHELKP_01015 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCGHELKP_01016 4.1e-43 E lipolytic protein G-D-S-L family
PCGHELKP_01017 1.7e-133 coaA 2.7.1.33 F Pantothenic acid kinase
PCGHELKP_01018 3.8e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PCGHELKP_01019 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PCGHELKP_01020 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PCGHELKP_01021 1.1e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PCGHELKP_01022 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
PCGHELKP_01023 1.1e-157 XK27_09615 S reductase
PCGHELKP_01024 1.2e-39 2.7.7.65 T phosphorelay sensor kinase activity
PCGHELKP_01025 4.2e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PCGHELKP_01026 2.4e-54 cps3I G Acyltransferase family
PCGHELKP_01027 3.6e-14
PCGHELKP_01028 1.6e-16 S Bacterial membrane protein YfhO
PCGHELKP_01029 1.3e-10 S Bacterial membrane protein YfhO
PCGHELKP_01030 2.8e-80 S Bacterial membrane protein YfhO
PCGHELKP_01031 1.6e-164 XK27_08315 M Sulfatase
PCGHELKP_01032 2.6e-60 S Psort location CytoplasmicMembrane, score
PCGHELKP_01033 1.4e-22 ganB 3.2.1.89 G arabinogalactan
PCGHELKP_01034 5.3e-78 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PCGHELKP_01035 8.3e-178 thrC 4.2.3.1 E Threonine synthase
PCGHELKP_01036 4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PCGHELKP_01037 8.8e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PCGHELKP_01038 1.6e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PCGHELKP_01040 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PCGHELKP_01041 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PCGHELKP_01042 4.3e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PCGHELKP_01043 7.1e-161 camS S sex pheromone
PCGHELKP_01044 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PCGHELKP_01045 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PCGHELKP_01046 4.3e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PCGHELKP_01047 3.4e-146 yegS 2.7.1.107 G Lipid kinase
PCGHELKP_01048 1.5e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCGHELKP_01049 1.3e-119 L Mrr N-terminal domain
PCGHELKP_01050 8.1e-17
PCGHELKP_01052 7.7e-72 S Beta-lactamase superfamily domain
PCGHELKP_01053 7.9e-50 K Cro/C1-type HTH DNA-binding domain
PCGHELKP_01054 8.8e-17 aguA_2 3.5.3.12 E Belongs to the agmatine deiminase family
PCGHELKP_01055 1.7e-97
PCGHELKP_01056 7.1e-43
PCGHELKP_01057 1e-173 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
PCGHELKP_01058 7.9e-50 K Cro/C1-type HTH DNA-binding domain
PCGHELKP_01059 4.5e-15 Z012_01675 S X-Pro dipeptidyl-peptidase (S15 family)
PCGHELKP_01060 9.4e-34 yjaB_1 K Acetyltransferase (GNAT) domain
PCGHELKP_01062 7.5e-239 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
PCGHELKP_01063 2.6e-76 S Fic/DOC family
PCGHELKP_01064 7.9e-11
PCGHELKP_01066 2.1e-62 ruvB 3.6.4.12 L four-way junction helicase activity
PCGHELKP_01070 3.8e-12 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
PCGHELKP_01071 7.5e-20
PCGHELKP_01074 6.1e-07
PCGHELKP_01079 5.8e-21 S Replication initiator protein A (RepA) N-terminus
PCGHELKP_01086 1.8e-16 3.4.21.88 K Peptidase S24-like
PCGHELKP_01088 1.5e-10 3.4.21.88 K Peptidase S24-like
PCGHELKP_01090 3.7e-162 3.1.21.3 L N-6 DNA Methylase
PCGHELKP_01092 6.3e-65 L ISXO2-like transposase domain
PCGHELKP_01093 7.8e-87 S Fic/DOC family
PCGHELKP_01094 6.7e-57 S peptidoglycan catabolic process
PCGHELKP_01096 8.4e-168 mdtG EGP Major facilitator Superfamily
PCGHELKP_01097 8.2e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PCGHELKP_01098 3.4e-84 treR K UTRA
PCGHELKP_01099 7.3e-259 treB G phosphotransferase system
PCGHELKP_01100 4.6e-63 3.1.3.73 G phosphoglycerate mutase
PCGHELKP_01101 9.2e-82 pncA Q isochorismatase
PCGHELKP_01102 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PCGHELKP_01103 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
PCGHELKP_01104 2.3e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PCGHELKP_01105 3.6e-41 K Transcriptional regulator, HxlR family
PCGHELKP_01106 2.9e-164 C Luciferase-like monooxygenase
PCGHELKP_01107 1.7e-67 1.5.1.38 S NADPH-dependent FMN reductase
PCGHELKP_01108 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PCGHELKP_01109 1.8e-76 L haloacid dehalogenase-like hydrolase
PCGHELKP_01110 1.8e-61 EG EamA-like transporter family
PCGHELKP_01111 3.1e-118 K AI-2E family transporter
PCGHELKP_01112 3.8e-173 malY 4.4.1.8 E Aminotransferase, class I
PCGHELKP_01113 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PCGHELKP_01114 7.8e-60 yfjR K WYL domain
PCGHELKP_01115 1.8e-11 S Mor transcription activator family
PCGHELKP_01117 1e-11 S zinc-ribbon domain
PCGHELKP_01118 2.8e-12 fhaB M Rib/alpha-like repeat
PCGHELKP_01119 2.9e-96 ypuA S Protein of unknown function (DUF1002)
PCGHELKP_01120 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
PCGHELKP_01121 1.1e-161 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PCGHELKP_01122 7.4e-18 yncA 2.3.1.79 S Maltose acetyltransferase
PCGHELKP_01123 6.9e-206 yflS P Sodium:sulfate symporter transmembrane region
PCGHELKP_01124 4.7e-199 frdC 1.3.5.4 C FAD binding domain
PCGHELKP_01125 1.5e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PCGHELKP_01126 4.4e-14 ybaN S Protein of unknown function (DUF454)
PCGHELKP_01127 4e-179 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PCGHELKP_01128 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PCGHELKP_01129 1.1e-95 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCGHELKP_01130 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PCGHELKP_01131 1.5e-71 ywlG S Belongs to the UPF0340 family
PCGHELKP_01132 4.4e-52 S Acetyltransferase (GNAT) domain
PCGHELKP_01135 3.8e-215 ugd 1.1.1.22 M UDP binding domain
PCGHELKP_01136 2.6e-77 epsB M biosynthesis protein
PCGHELKP_01137 2.7e-81 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PCGHELKP_01138 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
PCGHELKP_01139 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PCGHELKP_01140 9.1e-92 rfbP M Bacterial sugar transferase
PCGHELKP_01141 8.1e-67 cps3F
PCGHELKP_01142 1.1e-93 M transferase activity, transferring glycosyl groups
PCGHELKP_01143 1.3e-109 M Core-2/I-Branching enzyme
PCGHELKP_01144 2.8e-95 waaB GT4 M Glycosyl transferases group 1
PCGHELKP_01145 9.1e-112 S Psort location CytoplasmicMembrane, score
PCGHELKP_01146 2.8e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
PCGHELKP_01147 7.7e-189 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
PCGHELKP_01159 1.1e-21 ssb L Single-stranded DNA-binding protein
PCGHELKP_01160 1.7e-87 endA F DNA RNA non-specific endonuclease
PCGHELKP_01161 5.6e-133 NU StbA protein
PCGHELKP_01163 6.6e-08 S Uncharacterized protein pXO2-11
PCGHELKP_01164 4.3e-40
PCGHELKP_01165 3.8e-239 trsE S COG0433 Predicted ATPase
PCGHELKP_01167 3.3e-60 M Peptidase family M23
PCGHELKP_01170 4e-118 S Uncharacterised protein family (UPF0236)
PCGHELKP_01171 4.2e-45 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PCGHELKP_01172 6.5e-149 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PCGHELKP_01173 6.6e-38 S Replication initiator protein A (RepA) N-terminus
PCGHELKP_01174 1.6e-108 L Initiator Replication protein
PCGHELKP_01177 5.6e-181 L PLD-like domain
PCGHELKP_01178 1.6e-77 S Fic/DOC family
PCGHELKP_01179 8.7e-21 S Fic/DOC family
PCGHELKP_01180 9.9e-10 S Fic/DOC family
PCGHELKP_01181 8.3e-13 S Fic/DOC family
PCGHELKP_01182 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PCGHELKP_01183 1.7e-60 K DeoR C terminal sensor domain
PCGHELKP_01184 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PCGHELKP_01185 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PCGHELKP_01186 2.4e-192 cycA E Amino acid permease
PCGHELKP_01187 8.3e-187 ytgP S Polysaccharide biosynthesis protein
PCGHELKP_01188 5.7e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PCGHELKP_01189 5.4e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PCGHELKP_01190 6.6e-193 pepV 3.5.1.18 E dipeptidase PepV
PCGHELKP_01191 2.1e-215 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
PCGHELKP_01193 1.2e-84 V AAA domain (dynein-related subfamily)
PCGHELKP_01194 5.8e-68 S LlaJI restriction endonuclease
PCGHELKP_01197 1.5e-35
PCGHELKP_01198 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PCGHELKP_01199 4.2e-61 marR K Transcriptional regulator, MarR family
PCGHELKP_01200 2.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PCGHELKP_01201 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCGHELKP_01202 2.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PCGHELKP_01203 1.1e-98 IQ reductase
PCGHELKP_01204 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PCGHELKP_01205 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PCGHELKP_01206 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PCGHELKP_01207 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PCGHELKP_01208 1.4e-124 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PCGHELKP_01209 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PCGHELKP_01210 9.3e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PCGHELKP_01211 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PCGHELKP_01212 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
PCGHELKP_01213 5.5e-303 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PCGHELKP_01214 5.7e-119 gla U Major intrinsic protein
PCGHELKP_01215 1.5e-45 ykuL S CBS domain
PCGHELKP_01216 8.8e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PCGHELKP_01217 1.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PCGHELKP_01218 9e-87 ykuT M mechanosensitive ion channel
PCGHELKP_01220 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PCGHELKP_01221 2e-21 yheA S Belongs to the UPF0342 family
PCGHELKP_01222 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PCGHELKP_01223 2.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PCGHELKP_01225 5.4e-53 hit FG histidine triad
PCGHELKP_01226 9.8e-95 ecsA V ABC transporter, ATP-binding protein
PCGHELKP_01227 1.9e-71 ecsB U ABC transporter
PCGHELKP_01228 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
PCGHELKP_01229 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PCGHELKP_01230 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PCGHELKP_01231 8.1e-77 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PCGHELKP_01232 1.4e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
PCGHELKP_01233 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PCGHELKP_01234 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
PCGHELKP_01235 5.2e-69 ybhL S Belongs to the BI1 family
PCGHELKP_01236 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCGHELKP_01237 1.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PCGHELKP_01238 3.5e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PCGHELKP_01239 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PCGHELKP_01240 1.6e-79 dnaB L replication initiation and membrane attachment
PCGHELKP_01241 1.3e-107 dnaI L Primosomal protein DnaI
PCGHELKP_01242 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PCGHELKP_01243 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PCGHELKP_01244 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PCGHELKP_01245 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PCGHELKP_01246 1.6e-70 yqeG S HAD phosphatase, family IIIA
PCGHELKP_01247 4.6e-181 yqeH S Ribosome biogenesis GTPase YqeH
PCGHELKP_01248 6e-30 yhbY J RNA-binding protein
PCGHELKP_01249 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PCGHELKP_01250 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PCGHELKP_01251 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PCGHELKP_01252 6.5e-83 H Nodulation protein S (NodS)
PCGHELKP_01253 4.5e-123 ylbM S Belongs to the UPF0348 family
PCGHELKP_01254 2.3e-56 yceD S Uncharacterized ACR, COG1399
PCGHELKP_01255 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PCGHELKP_01256 4e-89 plsC 2.3.1.51 I Acyltransferase
PCGHELKP_01257 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
PCGHELKP_01258 1.5e-27 yazA L GIY-YIG catalytic domain protein
PCGHELKP_01259 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
PCGHELKP_01260 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PCGHELKP_01261 6.9e-37
PCGHELKP_01262 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PCGHELKP_01263 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PCGHELKP_01264 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PCGHELKP_01265 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PCGHELKP_01266 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PCGHELKP_01268 3.1e-111 K response regulator
PCGHELKP_01269 1.3e-167 arlS 2.7.13.3 T Histidine kinase
PCGHELKP_01270 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PCGHELKP_01271 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PCGHELKP_01272 1.8e-135 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PCGHELKP_01273 7.3e-105
PCGHELKP_01274 5.5e-117
PCGHELKP_01275 6.5e-41 dut S dUTPase
PCGHELKP_01276 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PCGHELKP_01277 3.7e-46 yqhY S Asp23 family, cell envelope-related function
PCGHELKP_01278 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PCGHELKP_01279 3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PCGHELKP_01280 5.8e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PCGHELKP_01281 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PCGHELKP_01282 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PCGHELKP_01283 2.6e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PCGHELKP_01284 6.6e-49 argR K Regulates arginine biosynthesis genes
PCGHELKP_01285 9.3e-178 recN L May be involved in recombinational repair of damaged DNA
PCGHELKP_01286 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PCGHELKP_01287 2.2e-30 ynzC S UPF0291 protein
PCGHELKP_01288 5.9e-27 yneF S UPF0154 protein
PCGHELKP_01289 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
PCGHELKP_01290 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PCGHELKP_01291 2.9e-76 yciQ P membrane protein (DUF2207)
PCGHELKP_01292 1.8e-19 D nuclear chromosome segregation
PCGHELKP_01293 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PCGHELKP_01294 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PCGHELKP_01295 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
PCGHELKP_01296 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
PCGHELKP_01297 4.7e-158 glk 2.7.1.2 G Glucokinase
PCGHELKP_01298 1.4e-45 yqhL P Rhodanese-like protein
PCGHELKP_01299 2.8e-16 WQ51_02665 S Protein of unknown function (DUF3042)
PCGHELKP_01300 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PCGHELKP_01301 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
PCGHELKP_01302 1.3e-45 glnR K Transcriptional regulator
PCGHELKP_01303 2e-247 glnA 6.3.1.2 E glutamine synthetase
PCGHELKP_01305 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PCGHELKP_01306 2.7e-48 S Domain of unknown function (DUF956)
PCGHELKP_01307 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PCGHELKP_01308 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PCGHELKP_01309 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PCGHELKP_01310 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
PCGHELKP_01311 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PCGHELKP_01312 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PCGHELKP_01313 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCGHELKP_01314 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
PCGHELKP_01315 4.8e-170 nusA K Participates in both transcription termination and antitermination
PCGHELKP_01316 1.4e-39 ylxR K Protein of unknown function (DUF448)
PCGHELKP_01317 6.9e-26 ylxQ J ribosomal protein
PCGHELKP_01318 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PCGHELKP_01319 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PCGHELKP_01320 8.2e-120 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PCGHELKP_01321 5.1e-96 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PCGHELKP_01322 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PCGHELKP_01323 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PCGHELKP_01324 4.5e-274 dnaK O Heat shock 70 kDa protein
PCGHELKP_01325 9.2e-161 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PCGHELKP_01326 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PCGHELKP_01328 4.6e-205 glnP P ABC transporter
PCGHELKP_01329 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCGHELKP_01330 1.5e-31
PCGHELKP_01331 5.9e-111 ampC V Beta-lactamase
PCGHELKP_01332 2.7e-110 cobQ S glutamine amidotransferase
PCGHELKP_01333 2.3e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PCGHELKP_01334 6.8e-86 tdk 2.7.1.21 F thymidine kinase
PCGHELKP_01335 1.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PCGHELKP_01336 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PCGHELKP_01337 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PCGHELKP_01338 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PCGHELKP_01339 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
PCGHELKP_01340 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PCGHELKP_01341 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PCGHELKP_01342 2.4e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PCGHELKP_01343 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PCGHELKP_01344 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PCGHELKP_01345 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PCGHELKP_01346 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PCGHELKP_01347 4.1e-15 ywzB S Protein of unknown function (DUF1146)
PCGHELKP_01348 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PCGHELKP_01349 1.2e-167 mbl D Cell shape determining protein MreB Mrl
PCGHELKP_01350 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PCGHELKP_01351 1.3e-13 S Protein of unknown function (DUF2969)
PCGHELKP_01352 6.1e-187 rodA D Belongs to the SEDS family
PCGHELKP_01353 2.1e-26 arsC 1.20.4.1 P Belongs to the ArsC family
PCGHELKP_01354 9.5e-94 2.7.1.89 M Phosphotransferase enzyme family
PCGHELKP_01355 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PCGHELKP_01356 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PCGHELKP_01357 3.7e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PCGHELKP_01358 1.6e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PCGHELKP_01359 4.4e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PCGHELKP_01360 2.6e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PCGHELKP_01361 1.9e-90 stp 3.1.3.16 T phosphatase
PCGHELKP_01362 5.7e-191 KLT serine threonine protein kinase
PCGHELKP_01363 1.1e-108 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PCGHELKP_01364 7.7e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
PCGHELKP_01365 4.4e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PCGHELKP_01366 5.6e-13 S RloB-like protein
PCGHELKP_01367 2e-57 S AAA domain, putative AbiEii toxin, Type IV TA system
PCGHELKP_01368 2.3e-25 L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PCGHELKP_01371 1.4e-44 3.4.22.70 M Sortase family
PCGHELKP_01372 1.2e-87 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
PCGHELKP_01373 2.1e-27 3.4.22.70 M Sortase family
PCGHELKP_01374 3.1e-06 M domain protein
PCGHELKP_01375 5e-23 S by MetaGeneAnnotator
PCGHELKP_01376 1.2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PCGHELKP_01377 3.1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
PCGHELKP_01378 1.1e-217 scrB 3.2.1.26 GH32 G invertase
PCGHELKP_01379 3.9e-147 scrR K helix_turn _helix lactose operon repressor
PCGHELKP_01382 1.3e-174 2.1.1.72, 3.1.21.3 V HsdM N-terminal domain
PCGHELKP_01386 2.9e-18 D nuclear chromosome segregation
PCGHELKP_01396 2.9e-14 bglG K CAT RNA binding domain
PCGHELKP_01397 9.6e-08 arbG1 K antiterminator
PCGHELKP_01398 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
PCGHELKP_01400 4.2e-35
PCGHELKP_01401 0.0 pepN 3.4.11.2 E aminopeptidase
PCGHELKP_01402 1.2e-44 2.7.13.3 T protein histidine kinase activity
PCGHELKP_01403 3e-35 agrA KT Response regulator of the LytR AlgR family
PCGHELKP_01404 6.3e-20 M domain protein
PCGHELKP_01405 6.3e-54 1.14.12.17 C Oxidoreductase NAD-binding domain
PCGHELKP_01410 0.0 O Belongs to the peptidase S8 family
PCGHELKP_01411 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PCGHELKP_01413 4.2e-45 yjaB_1 K Acetyltransferase (GNAT) domain
PCGHELKP_01414 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PCGHELKP_01415 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PCGHELKP_01416 5.4e-13
PCGHELKP_01417 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
PCGHELKP_01418 2.5e-91 yunF F Protein of unknown function DUF72
PCGHELKP_01419 2.9e-156 nrnB S DHHA1 domain
PCGHELKP_01420 1.8e-42 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PCGHELKP_01421 7.6e-60
PCGHELKP_01422 2.9e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
PCGHELKP_01423 2e-22 S Cytochrome B5
PCGHELKP_01424 8.1e-20 sigH K DNA-templated transcription, initiation
PCGHELKP_01425 6.9e-70 recX 2.4.1.337 GT4 S Regulatory protein RecX
PCGHELKP_01426 2.4e-32 tetR K transcriptional regulator
PCGHELKP_01427 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
PCGHELKP_01428 5e-255 XK27_06780 V ABC transporter permease
PCGHELKP_01429 5.2e-25 D nuclear chromosome segregation
PCGHELKP_01431 5.7e-08
PCGHELKP_01432 2.4e-106 L Belongs to the 'phage' integrase family
PCGHELKP_01433 1.9e-137 tetA EGP Major facilitator Superfamily
PCGHELKP_01435 3.4e-70 rny D Peptidase family M23
PCGHELKP_01436 7.5e-44 L hmm pf00665
PCGHELKP_01437 1.5e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PCGHELKP_01438 3.2e-85 dps P Ferritin-like domain
PCGHELKP_01439 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PCGHELKP_01440 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCGHELKP_01441 1.1e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PCGHELKP_01442 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCGHELKP_01443 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PCGHELKP_01444 8e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PCGHELKP_01445 2.3e-41 yabR J RNA binding
PCGHELKP_01446 1e-21 divIC D Septum formation initiator
PCGHELKP_01447 3.1e-30 yabO J S4 domain protein
PCGHELKP_01448 2.1e-139 yabM S Polysaccharide biosynthesis protein
PCGHELKP_01449 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PCGHELKP_01450 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PCGHELKP_01451 8.1e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PCGHELKP_01452 5.5e-86 S (CBS) domain
PCGHELKP_01453 3.1e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PCGHELKP_01454 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PCGHELKP_01455 7.2e-53 perR P Belongs to the Fur family
PCGHELKP_01456 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
PCGHELKP_01457 2.7e-98 sbcC L Putative exonuclease SbcCD, C subunit
PCGHELKP_01458 5.7e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PCGHELKP_01459 5.5e-45 M LysM domain protein
PCGHELKP_01460 5.6e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PCGHELKP_01461 8.2e-86 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PCGHELKP_01462 3e-34 ygfC K Bacterial regulatory proteins, tetR family
PCGHELKP_01463 4.5e-101 hrtB V ABC transporter permease
PCGHELKP_01464 2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PCGHELKP_01465 1e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PCGHELKP_01466 0.0 helD 3.6.4.12 L DNA helicase
PCGHELKP_01467 8.9e-246 yjbQ P TrkA C-terminal domain protein
PCGHELKP_01468 6.1e-31
PCGHELKP_01469 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
PCGHELKP_01470 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PCGHELKP_01471 9.4e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PCGHELKP_01472 2.2e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PCGHELKP_01473 5.2e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PCGHELKP_01474 2.3e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PCGHELKP_01475 4.8e-53 rplQ J Ribosomal protein L17
PCGHELKP_01476 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCGHELKP_01477 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PCGHELKP_01478 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PCGHELKP_01479 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PCGHELKP_01480 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PCGHELKP_01481 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PCGHELKP_01482 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PCGHELKP_01483 1e-67 rplO J Binds to the 23S rRNA
PCGHELKP_01484 2.1e-22 rpmD J Ribosomal protein L30
PCGHELKP_01485 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PCGHELKP_01486 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PCGHELKP_01487 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PCGHELKP_01488 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PCGHELKP_01489 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PCGHELKP_01490 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PCGHELKP_01491 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PCGHELKP_01492 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PCGHELKP_01493 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PCGHELKP_01494 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
PCGHELKP_01495 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PCGHELKP_01496 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PCGHELKP_01497 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PCGHELKP_01498 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PCGHELKP_01499 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PCGHELKP_01500 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PCGHELKP_01501 1e-100 rplD J Forms part of the polypeptide exit tunnel
PCGHELKP_01502 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PCGHELKP_01503 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PCGHELKP_01504 6.2e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PCGHELKP_01505 6.5e-79 K rpiR family
PCGHELKP_01506 1.4e-52 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PCGHELKP_01507 8.5e-147 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
PCGHELKP_01508 6.5e-21 K Acetyltransferase (GNAT) domain
PCGHELKP_01509 6.4e-182 steT E amino acid
PCGHELKP_01510 2.9e-82 glnP P ABC transporter permease
PCGHELKP_01511 1.2e-85 gluC P ABC transporter permease
PCGHELKP_01512 1.9e-99 glnH ET ABC transporter
PCGHELKP_01513 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PCGHELKP_01514 1.4e-14
PCGHELKP_01515 5e-98
PCGHELKP_01517 3.2e-53 zur P Belongs to the Fur family
PCGHELKP_01518 3.7e-212 yfnA E Amino Acid
PCGHELKP_01519 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PCGHELKP_01520 0.0 L Helicase C-terminal domain protein
PCGHELKP_01521 2e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
PCGHELKP_01522 2.1e-180 yhdP S Transporter associated domain
PCGHELKP_01523 1.4e-25
PCGHELKP_01524 2.4e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PCGHELKP_01525 9.6e-132 bacI V MacB-like periplasmic core domain
PCGHELKP_01526 9.6e-97 V ABC transporter
PCGHELKP_01527 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCGHELKP_01528 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
PCGHELKP_01529 3.6e-140 V MatE
PCGHELKP_01530 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PCGHELKP_01531 5e-87 S Alpha beta hydrolase
PCGHELKP_01532 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PCGHELKP_01533 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PCGHELKP_01534 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
PCGHELKP_01535 3.2e-101 IQ Enoyl-(Acyl carrier protein) reductase
PCGHELKP_01536 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
PCGHELKP_01537 9.6e-54 queT S QueT transporter
PCGHELKP_01539 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
PCGHELKP_01540 1.1e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCGHELKP_01541 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCGHELKP_01542 5.5e-34 trxA O Belongs to the thioredoxin family
PCGHELKP_01543 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
PCGHELKP_01544 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PCGHELKP_01545 1.3e-49 S Threonine/Serine exporter, ThrE
PCGHELKP_01546 4.3e-82 thrE S Putative threonine/serine exporter
PCGHELKP_01547 3.1e-27 cspC K Cold shock protein
PCGHELKP_01548 3.1e-89 sirR K Helix-turn-helix diphteria tox regulatory element
PCGHELKP_01549 2.4e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PCGHELKP_01550 1.2e-22
PCGHELKP_01551 1.2e-58 3.6.1.27 I phosphatase
PCGHELKP_01552 3.1e-25
PCGHELKP_01553 2.1e-66 I alpha/beta hydrolase fold
PCGHELKP_01554 1.3e-38 azlD S branched-chain amino acid
PCGHELKP_01555 1.1e-104 azlC E AzlC protein
PCGHELKP_01556 2e-17
PCGHELKP_01557 2.2e-119 xth 3.1.11.2 L exodeoxyribonuclease III
PCGHELKP_01558 5.8e-100 V domain protein
PCGHELKP_01559 7.2e-18
PCGHELKP_01562 1e-54 tlpA2 L Transposase IS200 like
PCGHELKP_01563 3.8e-92 L Transposase, IS605 OrfB family
PCGHELKP_01564 1.7e-158 L transposase, IS605 OrfB family
PCGHELKP_01569 2.1e-07
PCGHELKP_01571 3.9e-40 tlpA2 L Transposase IS200 like
PCGHELKP_01572 7.9e-21 L Helix-turn-helix domain
PCGHELKP_01573 1.5e-34 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PCGHELKP_01574 3.7e-84 2.7.7.12 C Domain of unknown function (DUF4931)
PCGHELKP_01575 2.6e-91 T Calcineurin-like phosphoesterase superfamily domain
PCGHELKP_01576 4.2e-49 lytE M LysM domain protein
PCGHELKP_01577 5e-19 glpE P Rhodanese Homology Domain
PCGHELKP_01578 3.1e-27 xlyB 3.5.1.28 CBM50 M LysM domain
PCGHELKP_01579 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
PCGHELKP_01580 2.1e-194 cydA 1.10.3.14 C ubiquinol oxidase
PCGHELKP_01581 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PCGHELKP_01582 7.8e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PCGHELKP_01583 1.8e-219 cydD CO ABC transporter transmembrane region
PCGHELKP_01584 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PCGHELKP_01585 4.4e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PCGHELKP_01586 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
PCGHELKP_01587 6.2e-145 pbuO_1 S Permease family
PCGHELKP_01588 7.3e-44 2.7.7.65 T GGDEF domain
PCGHELKP_01589 3.3e-128 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
PCGHELKP_01590 7.1e-182
PCGHELKP_01591 5.8e-206 S Protein conserved in bacteria
PCGHELKP_01592 1.2e-201 ydaM M Glycosyl transferase family group 2
PCGHELKP_01593 0.0 ydaN S Bacterial cellulose synthase subunit
PCGHELKP_01594 2.4e-113 2.7.7.65 T diguanylate cyclase activity
PCGHELKP_01595 5.9e-39 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
PCGHELKP_01596 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
PCGHELKP_01597 1.2e-308 L Helicase C-terminal domain protein
PCGHELKP_01598 3.6e-60 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
PCGHELKP_01599 0.0 rafA 3.2.1.22 G alpha-galactosidase
PCGHELKP_01600 1.5e-53 S Membrane
PCGHELKP_01601 9.1e-65 K helix_turn_helix, arabinose operon control protein
PCGHELKP_01602 9.5e-44
PCGHELKP_01603 4.5e-205 pipD E Dipeptidase
PCGHELKP_01604 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PCGHELKP_01605 7e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PCGHELKP_01606 5.6e-60 speG J Acetyltransferase (GNAT) domain
PCGHELKP_01607 2.3e-113 yitU 3.1.3.104 S hydrolase
PCGHELKP_01608 1.2e-82 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PCGHELKP_01609 8.1e-81
PCGHELKP_01610 7.7e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PCGHELKP_01611 1.8e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PCGHELKP_01612 1.2e-47 cps4C M Chain length determinant protein
PCGHELKP_01613 7.2e-65 cpsD D AAA domain
PCGHELKP_01614 6.9e-219 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
PCGHELKP_01615 2.4e-167 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
PCGHELKP_01616 2.3e-76 epsL M Bacterial sugar transferase
PCGHELKP_01617 6.5e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
PCGHELKP_01618 6.2e-122 2.4.1.52 GT4 M Glycosyl transferases group 1
PCGHELKP_01619 1e-82 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
PCGHELKP_01620 4.4e-75 M Glycosyltransferase Family 4
PCGHELKP_01621 4.3e-41 GT2 S Glycosyltransferase
PCGHELKP_01622 2.7e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
PCGHELKP_01623 1.1e-06 S EpsG family
PCGHELKP_01624 2.7e-25 S Psort location Cytoplasmic, score
PCGHELKP_01625 2.9e-16
PCGHELKP_01626 1.5e-115 S Glycosyltransferase WbsX
PCGHELKP_01627 6.8e-116 S Glycosyltransferase WbsX
PCGHELKP_01628 3.4e-102 cps2I S Psort location CytoplasmicMembrane, score
PCGHELKP_01629 1.1e-144 lspL 5.1.3.6 GM RmlD substrate binding domain
PCGHELKP_01630 2.4e-178 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PCGHELKP_01631 1.1e-71 M Glycosyl transferases group 1
PCGHELKP_01632 2.6e-70 M Glycosyl transferases group 1
PCGHELKP_01633 5.8e-10
PCGHELKP_01634 1.2e-83 qorB 1.6.5.2 GM NmrA-like family
PCGHELKP_01635 6.6e-41 K Transcriptional regulator
PCGHELKP_01636 2.7e-30 S CHY zinc finger
PCGHELKP_01637 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
PCGHELKP_01639 3.4e-41 S Protein of unknown function (DUF1211)
PCGHELKP_01640 1.8e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
PCGHELKP_01642 3.3e-41 wecD M Acetyltransferase (GNAT) family
PCGHELKP_01643 1.4e-77 cps2D 5.1.3.2 M RmlD substrate binding domain
PCGHELKP_01644 1.5e-66 H Methyltransferase domain
PCGHELKP_01646 3.7e-16 K DNA-templated transcription, initiation
PCGHELKP_01648 2.2e-08 S Protein of unknown function (DUF2922)
PCGHELKP_01650 1e-59 S RRXRR protein
PCGHELKP_01653 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
PCGHELKP_01654 1e-27 ysxB J Cysteine protease Prp
PCGHELKP_01655 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PCGHELKP_01656 3.7e-12
PCGHELKP_01658 1.4e-71
PCGHELKP_01659 1.8e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PCGHELKP_01660 6.6e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PCGHELKP_01661 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PCGHELKP_01662 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PCGHELKP_01663 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PCGHELKP_01664 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PCGHELKP_01665 2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PCGHELKP_01666 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PCGHELKP_01667 3.4e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PCGHELKP_01668 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PCGHELKP_01669 4.1e-51 yeaL S Protein of unknown function (DUF441)
PCGHELKP_01670 1.8e-124 cvfB S S1 domain
PCGHELKP_01671 1.2e-112 xerD D recombinase XerD
PCGHELKP_01672 1.9e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PCGHELKP_01673 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PCGHELKP_01674 3.7e-188 nhaC C Na H antiporter NhaC
PCGHELKP_01675 4.3e-63 ypsA S Belongs to the UPF0398 family
PCGHELKP_01676 5.5e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
PCGHELKP_01677 9e-30 yqkB S Belongs to the HesB IscA family
PCGHELKP_01678 6e-66 yxkH G Polysaccharide deacetylase
PCGHELKP_01679 1.8e-07
PCGHELKP_01680 3.8e-53 K LysR substrate binding domain
PCGHELKP_01681 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
PCGHELKP_01682 1.1e-199 nupG F Nucleoside
PCGHELKP_01683 5.3e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PCGHELKP_01684 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PCGHELKP_01685 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PCGHELKP_01686 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PCGHELKP_01687 6.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PCGHELKP_01688 9e-20 yaaA S S4 domain protein YaaA
PCGHELKP_01689 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PCGHELKP_01690 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCGHELKP_01691 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCGHELKP_01692 6.2e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
PCGHELKP_01693 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PCGHELKP_01694 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PCGHELKP_01695 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PCGHELKP_01696 5.6e-117 S Glycosyl transferase family 2
PCGHELKP_01697 7.4e-64 D peptidase
PCGHELKP_01698 0.0 asnB 6.3.5.4 E Asparagine synthase
PCGHELKP_01699 3.7e-37 yiiE S Protein of unknown function (DUF1211)
PCGHELKP_01700 3.3e-12 yiiE S Protein of unknown function (DUF1211)
PCGHELKP_01701 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PCGHELKP_01702 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PCGHELKP_01703 3.6e-17 yneR
PCGHELKP_01704 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PCGHELKP_01705 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
PCGHELKP_01706 1.3e-98 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PCGHELKP_01707 1.1e-151 mdtG EGP Major facilitator Superfamily
PCGHELKP_01708 3.8e-14 yobS K transcriptional regulator
PCGHELKP_01709 2.8e-109 glcU U sugar transport
PCGHELKP_01710 4.4e-170 yjjP S Putative threonine/serine exporter
PCGHELKP_01711 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
PCGHELKP_01712 2.2e-96 yicL EG EamA-like transporter family
PCGHELKP_01713 1.8e-222 pepF E Oligopeptidase F
PCGHELKP_01714 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PCGHELKP_01715 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PCGHELKP_01716 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
PCGHELKP_01717 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PCGHELKP_01718 4e-23 relB L RelB antitoxin
PCGHELKP_01720 8.3e-172 S Putative peptidoglycan binding domain
PCGHELKP_01721 1.2e-31 K Transcriptional regulator, MarR family
PCGHELKP_01722 2e-215 XK27_09600 V ABC transporter, ATP-binding protein
PCGHELKP_01723 1.1e-229 V ABC transporter transmembrane region
PCGHELKP_01725 4.3e-96 S Domain of unknown function DUF87
PCGHELKP_01727 4.7e-106 yxeH S hydrolase
PCGHELKP_01728 1.8e-120 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PCGHELKP_01729 9e-114 K response regulator
PCGHELKP_01730 1.1e-272 vicK 2.7.13.3 T Histidine kinase
PCGHELKP_01731 2.7e-103 yycH S YycH protein
PCGHELKP_01732 3.6e-79 yycI S YycH protein
PCGHELKP_01733 5.1e-16 yyaQ S YjbR
PCGHELKP_01734 1.3e-116 vicX 3.1.26.11 S domain protein
PCGHELKP_01735 3.7e-145 htrA 3.4.21.107 O serine protease
PCGHELKP_01736 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PCGHELKP_01737 7.2e-208 G glycerol-3-phosphate transporter
PCGHELKP_01738 8.3e-138 S interspecies interaction between organisms
PCGHELKP_01739 7.1e-66 secY2 U SecY translocase
PCGHELKP_01740 1.7e-77 asp1 S Accessory Sec system protein Asp1
PCGHELKP_01743 5.5e-149 mepA V MATE efflux family protein
PCGHELKP_01744 6e-152 lsa S ABC transporter
PCGHELKP_01745 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PCGHELKP_01746 1e-109 puuD S peptidase C26
PCGHELKP_01747 2.9e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PCGHELKP_01748 1.1e-25
PCGHELKP_01749 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
PCGHELKP_01750 1.1e-59 uspA T Universal stress protein family
PCGHELKP_01752 1.1e-209 glnP P ABC transporter
PCGHELKP_01753 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PCGHELKP_01754 1.6e-114 ntpJ P Potassium uptake protein
PCGHELKP_01755 2.8e-58 ktrA P TrkA-N domain
PCGHELKP_01756 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PCGHELKP_01757 4.4e-37 M Glycosyltransferase group 2 family protein
PCGHELKP_01758 1.4e-19
PCGHELKP_01759 1.4e-94 S Predicted membrane protein (DUF2207)
PCGHELKP_01760 2.1e-54 bioY S BioY family
PCGHELKP_01761 1.3e-183 lmrB EGP Major facilitator Superfamily
PCGHELKP_01762 3.7e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PCGHELKP_01763 7.6e-74 glcR K DeoR C terminal sensor domain
PCGHELKP_01764 7.7e-61 yceE S haloacid dehalogenase-like hydrolase
PCGHELKP_01765 1.7e-31 S CAAX protease self-immunity
PCGHELKP_01766 5.3e-34 S Domain of unknown function (DUF4811)
PCGHELKP_01767 2.1e-197 lmrB EGP Major facilitator Superfamily
PCGHELKP_01768 7.1e-32 merR K MerR HTH family regulatory protein
PCGHELKP_01769 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PCGHELKP_01770 1.7e-69 S Protein of unknown function (DUF554)
PCGHELKP_01771 1.4e-120 G Bacterial extracellular solute-binding protein
PCGHELKP_01772 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
PCGHELKP_01773 2.3e-99 baeS T Histidine kinase
PCGHELKP_01774 2.4e-80 rbsB G sugar-binding domain protein
PCGHELKP_01775 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PCGHELKP_01776 6.4e-116 manY G PTS system sorbose-specific iic component
PCGHELKP_01777 8e-147 manN G system, mannose fructose sorbose family IID component
PCGHELKP_01778 1.8e-52 manO S Domain of unknown function (DUF956)
PCGHELKP_01779 3.6e-71 L PFAM transposase IS200-family protein
PCGHELKP_01780 4.3e-16 S Protein of unknown function (DUF805)
PCGHELKP_01782 2.3e-84 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PCGHELKP_01783 9.2e-71 mltD CBM50 M NlpC P60 family protein
PCGHELKP_01784 5.2e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PCGHELKP_01785 8.4e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCGHELKP_01786 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
PCGHELKP_01787 5.6e-46 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PCGHELKP_01788 8.1e-38 K transcriptional regulator PadR family
PCGHELKP_01789 7.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
PCGHELKP_01790 1.5e-15 S Putative adhesin
PCGHELKP_01791 7.5e-10 pspC KT PspC domain
PCGHELKP_01792 3.9e-13 S Enterocin A Immunity
PCGHELKP_01793 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PCGHELKP_01794 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
PCGHELKP_01795 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PCGHELKP_01796 6.3e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PCGHELKP_01797 1.5e-120 potB P ABC transporter permease
PCGHELKP_01798 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
PCGHELKP_01799 1.3e-159 potD P ABC transporter
PCGHELKP_01800 3.5e-132 ABC-SBP S ABC transporter
PCGHELKP_01801 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PCGHELKP_01802 5.2e-107 XK27_08845 S ABC transporter, ATP-binding protein
PCGHELKP_01803 4.4e-67 M ErfK YbiS YcfS YnhG
PCGHELKP_01804 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PCGHELKP_01805 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PCGHELKP_01806 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PCGHELKP_01807 1.2e-102 pgm3 G phosphoglycerate mutase
PCGHELKP_01808 3.6e-56 S CAAX protease self-immunity
PCGHELKP_01809 4.8e-47 C Flavodoxin
PCGHELKP_01810 1.1e-55 yphH S Cupin domain
PCGHELKP_01811 1.4e-45 yphJ 4.1.1.44 S decarboxylase
PCGHELKP_01812 3.5e-144 E methionine synthase, vitamin-B12 independent
PCGHELKP_01813 1.8e-108 metQ1 P Belongs to the nlpA lipoprotein family
PCGHELKP_01814 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCGHELKP_01815 1.3e-69 metI P ABC transporter permease
PCGHELKP_01816 6.7e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PCGHELKP_01817 3e-84 drgA C nitroreductase
PCGHELKP_01818 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PCGHELKP_01819 2.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PCGHELKP_01820 1.3e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PCGHELKP_01821 1.7e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
PCGHELKP_01823 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCGHELKP_01824 2.4e-31 metI U ABC transporter permease
PCGHELKP_01825 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
PCGHELKP_01826 3.2e-58 S Protein of unknown function (DUF4256)
PCGHELKP_01829 4.3e-104 pfoS S Phosphotransferase system, EIIC
PCGHELKP_01830 4.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PCGHELKP_01831 3.4e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PCGHELKP_01832 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PCGHELKP_01833 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
PCGHELKP_01834 1.6e-156 amtB P ammonium transporter
PCGHELKP_01835 1.8e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PCGHELKP_01836 6.6e-46 argR K Regulates arginine biosynthesis genes
PCGHELKP_01837 3.6e-133 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
PCGHELKP_01838 2.9e-90 S Alpha/beta hydrolase of unknown function (DUF915)
PCGHELKP_01839 2.7e-22 veg S Biofilm formation stimulator VEG
PCGHELKP_01840 3.7e-133 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PCGHELKP_01841 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PCGHELKP_01842 1e-102 tatD L hydrolase, TatD family
PCGHELKP_01843 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCGHELKP_01844 5.1e-128
PCGHELKP_01845 2.3e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PCGHELKP_01846 1.9e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
PCGHELKP_01847 1.8e-31 K Transcriptional regulator
PCGHELKP_01848 2.7e-104 ybhR V ABC transporter
PCGHELKP_01849 4.2e-82 ybhF_2 V abc transporter atp-binding protein
PCGHELKP_01850 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PCGHELKP_01851 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PCGHELKP_01852 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PCGHELKP_01853 8.8e-272 helD 3.6.4.12 L DNA helicase
PCGHELKP_01855 1.3e-114 htpX O Belongs to the peptidase M48B family
PCGHELKP_01856 8.7e-72 lemA S LemA family
PCGHELKP_01857 1.4e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
PCGHELKP_01858 1.1e-45 yjcF K protein acetylation
PCGHELKP_01860 7.4e-253 yfiC V ABC transporter
PCGHELKP_01861 8.9e-224 lmrA V ABC transporter, ATP-binding protein
PCGHELKP_01862 5.8e-35 K Bacterial regulatory proteins, tetR family
PCGHELKP_01863 5.6e-246 yhcA V ABC transporter, ATP-binding protein
PCGHELKP_01864 7e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PCGHELKP_01865 8.6e-146 G Transporter, major facilitator family protein
PCGHELKP_01866 1.7e-90 lacX 5.1.3.3 G Aldose 1-epimerase
PCGHELKP_01867 1.7e-141 hpk31 2.7.13.3 T Histidine kinase
PCGHELKP_01868 2.5e-113 K response regulator
PCGHELKP_01869 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
PCGHELKP_01870 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PCGHELKP_01871 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PCGHELKP_01872 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PCGHELKP_01873 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PCGHELKP_01874 4.3e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PCGHELKP_01875 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCGHELKP_01876 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PCGHELKP_01877 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PCGHELKP_01878 1.6e-55 ctsR K Belongs to the CtsR family
PCGHELKP_01880 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PCGHELKP_01881 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PCGHELKP_01882 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PCGHELKP_01883 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PCGHELKP_01884 2.9e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PCGHELKP_01886 1.1e-25 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PCGHELKP_01887 2.4e-121 ytbE S reductase
PCGHELKP_01888 9.3e-43 ytcD K HxlR-like helix-turn-helix
PCGHELKP_01889 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
PCGHELKP_01890 2e-67 ybbL S ABC transporter
PCGHELKP_01891 6.2e-163 oxlT P Major Facilitator Superfamily
PCGHELKP_01892 1.1e-52 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PCGHELKP_01893 9.2e-47 S Short repeat of unknown function (DUF308)
PCGHELKP_01894 1.4e-30 tetR K Transcriptional regulator C-terminal region
PCGHELKP_01895 1.2e-150 yfeX P Peroxidase
PCGHELKP_01896 2.5e-16 S Protein of unknown function (DUF3021)
PCGHELKP_01897 4.5e-39 K LytTr DNA-binding domain
PCGHELKP_01898 1.1e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PCGHELKP_01899 1.7e-209 mmuP E amino acid
PCGHELKP_01900 5.4e-16 psiE S Phosphate-starvation-inducible E
PCGHELKP_01901 3.7e-155 oppF P Belongs to the ABC transporter superfamily
PCGHELKP_01902 1.3e-180 oppD P Belongs to the ABC transporter superfamily
PCGHELKP_01903 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCGHELKP_01904 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCGHELKP_01905 4e-202 oppA E ABC transporter, substratebinding protein
PCGHELKP_01906 1.6e-218 yifK E Amino acid permease
PCGHELKP_01907 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PCGHELKP_01908 1.5e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PCGHELKP_01909 5e-66 pgm3 G phosphoglycerate mutase family
PCGHELKP_01910 1.2e-250 ctpA 3.6.3.54 P P-type ATPase
PCGHELKP_01911 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PCGHELKP_01912 2.6e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PCGHELKP_01913 3.7e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PCGHELKP_01914 1.8e-181 EG GntP family permease
PCGHELKP_01915 5e-116 KT Putative sugar diacid recognition
PCGHELKP_01916 3.1e-22 K transcriptional regulator
PCGHELKP_01917 6.1e-75 hchA S intracellular protease amidase
PCGHELKP_01918 6.2e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PCGHELKP_01919 3.7e-113 lacI3 K helix_turn _helix lactose operon repressor
PCGHELKP_01920 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
PCGHELKP_01921 7.5e-39 2.7.1.191 G PTS system fructose IIA component
PCGHELKP_01922 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
PCGHELKP_01923 4.4e-101 G PTS system sorbose-specific iic component
PCGHELKP_01924 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
PCGHELKP_01925 8.7e-81 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PCGHELKP_01926 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PCGHELKP_01927 2.6e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
PCGHELKP_01928 1.1e-116 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
PCGHELKP_01929 6.9e-198 1.3.5.4 C FMN_bind
PCGHELKP_01930 2.2e-56 3.1.3.48 K Transcriptional regulator
PCGHELKP_01931 2.2e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PCGHELKP_01932 3.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PCGHELKP_01933 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PCGHELKP_01934 1.6e-128 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
PCGHELKP_01935 4.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PCGHELKP_01936 1.6e-81 S Belongs to the UPF0246 family
PCGHELKP_01937 7.9e-12 V CAAX protease self-immunity
PCGHELKP_01938 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
PCGHELKP_01939 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PCGHELKP_01941 7.4e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PCGHELKP_01942 4e-64 C FMN binding
PCGHELKP_01943 1.2e-205 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PCGHELKP_01944 1.7e-54 rplI J Binds to the 23S rRNA
PCGHELKP_01945 4.4e-262 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PCGHELKP_01946 1.4e-06

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)