ORF_ID e_value Gene_name EC_number CAZy COGs Description
PGKGLPEO_00001 0.0 S FAD binding domain
PGKGLPEO_00002 2.5e-158 S hydrolases of the HAD superfamily
PGKGLPEO_00003 2.6e-195 S AI-2E family transporter
PGKGLPEO_00004 2.5e-103 yyaR K Acetyltransferase (GNAT) domain
PGKGLPEO_00005 8.4e-99 yxaF_1 K Transcriptional regulator
PGKGLPEO_00006 2.7e-269 lmrB EGP the major facilitator superfamily
PGKGLPEO_00007 1.9e-245 EGP Major facilitator Superfamily
PGKGLPEO_00008 1.6e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PGKGLPEO_00009 1.1e-74 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
PGKGLPEO_00010 3.2e-32 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C hydroxyacid-oxoacid transhydrogenase activity
PGKGLPEO_00011 2.3e-161 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PGKGLPEO_00012 8.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
PGKGLPEO_00013 1.7e-284 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PGKGLPEO_00014 4.5e-168 araC1 K AraC-like ligand binding domain
PGKGLPEO_00015 4e-209 L Transposase IS4 family protein
PGKGLPEO_00016 1.7e-122 S Nuclease-related domain
PGKGLPEO_00017 1e-54 L COG2963 Transposase and inactivated derivatives
PGKGLPEO_00018 2.1e-148 L COG2801 Transposase and inactivated derivatives
PGKGLPEO_00019 1e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PGKGLPEO_00020 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
PGKGLPEO_00021 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PGKGLPEO_00022 9.5e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PGKGLPEO_00024 5.4e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PGKGLPEO_00025 1.3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PGKGLPEO_00026 4.2e-112 rsmC 2.1.1.172 J Methyltransferase
PGKGLPEO_00027 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGKGLPEO_00028 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGKGLPEO_00029 2.6e-36 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
PGKGLPEO_00030 8.6e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PGKGLPEO_00031 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PGKGLPEO_00032 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PGKGLPEO_00033 1.4e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PGKGLPEO_00034 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PGKGLPEO_00035 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PGKGLPEO_00036 1.7e-108 rplD J Forms part of the polypeptide exit tunnel
PGKGLPEO_00037 1.7e-42 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PGKGLPEO_00038 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PGKGLPEO_00039 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PGKGLPEO_00040 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PGKGLPEO_00041 2.3e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PGKGLPEO_00042 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PGKGLPEO_00043 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
PGKGLPEO_00044 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PGKGLPEO_00045 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PGKGLPEO_00046 1.7e-57 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PGKGLPEO_00047 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PGKGLPEO_00048 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGKGLPEO_00049 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PGKGLPEO_00050 6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PGKGLPEO_00051 6.1e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PGKGLPEO_00052 4.7e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PGKGLPEO_00053 7e-23 rpmD J Ribosomal protein L30
PGKGLPEO_00054 1.2e-71 rplO J binds to the 23S rRNA
PGKGLPEO_00055 1.4e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PGKGLPEO_00056 1.1e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PGKGLPEO_00057 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PGKGLPEO_00058 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PGKGLPEO_00059 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PGKGLPEO_00060 5.8e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGKGLPEO_00061 2.8e-59 rplQ J Ribosomal protein L17
PGKGLPEO_00063 1.8e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGKGLPEO_00064 7.8e-160 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGKGLPEO_00065 6e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGKGLPEO_00066 7.9e-129 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PGKGLPEO_00067 9.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PGKGLPEO_00068 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PGKGLPEO_00069 5.3e-178 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PGKGLPEO_00070 4.4e-208 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PGKGLPEO_00071 0.0 S type I phosphodiesterase nucleotide pyrophosphatase
PGKGLPEO_00073 4.4e-227 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
PGKGLPEO_00074 7.2e-112 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
PGKGLPEO_00075 1.9e-275 lysP E amino acid
PGKGLPEO_00076 8.8e-83 ybaK S Protein of unknown function (DUF2521)
PGKGLPEO_00077 6.2e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PGKGLPEO_00078 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PGKGLPEO_00079 4.8e-70 gerD S Spore gernimation protein
PGKGLPEO_00080 3.9e-108 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
PGKGLPEO_00081 8.7e-217 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
PGKGLPEO_00082 5.5e-138 pdaB 3.5.1.104 G xylanase chitin deacetylase
PGKGLPEO_00083 2.6e-30
PGKGLPEO_00084 1.3e-262 cydA 1.10.3.14 C oxidase, subunit
PGKGLPEO_00085 8.4e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
PGKGLPEO_00086 0.0 cydD V ATP-binding
PGKGLPEO_00087 0.0 cydD V ATP-binding protein
PGKGLPEO_00088 2.6e-161 EGP Major facilitator Superfamily
PGKGLPEO_00089 1.1e-28 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGKGLPEO_00090 3.2e-189 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGKGLPEO_00091 1.1e-70 cas4 3.1.12.1 L Domain of unknown function DUF83
PGKGLPEO_00092 0.0 cas3 L CRISPR-associated helicase, Cas3
PGKGLPEO_00093 6.1e-145 cas5h S CRISPR-associated protein Cas5
PGKGLPEO_00094 4.1e-178 L CRISPR-associated protein Cas7
PGKGLPEO_00095 0.0 csh
PGKGLPEO_00096 1.4e-127 cas6 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
PGKGLPEO_00097 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PGKGLPEO_00098 3.6e-108 C Nitroreductase family
PGKGLPEO_00099 1.2e-88 1.8.5.2 S DoxX
PGKGLPEO_00100 3.4e-197 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PGKGLPEO_00101 9.1e-116 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PGKGLPEO_00102 6e-35 yoeD G Helix-turn-helix domain
PGKGLPEO_00103 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
PGKGLPEO_00104 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PGKGLPEO_00105 3.2e-133 fruR K Transcriptional regulator
PGKGLPEO_00106 6.5e-204 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PGKGLPEO_00107 6.6e-93 D Hemerythrin HHE cation binding
PGKGLPEO_00108 2.5e-152 yidA S hydrolases of the HAD superfamily
PGKGLPEO_00109 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
PGKGLPEO_00110 3e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system
PGKGLPEO_00111 4.1e-273 iolT EGP Major facilitator Superfamily
PGKGLPEO_00112 6.3e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PGKGLPEO_00114 6.2e-73 ywnF S Family of unknown function (DUF5392)
PGKGLPEO_00115 5.8e-135 ywaC 2.7.6.5 S protein conserved in bacteria
PGKGLPEO_00116 4.1e-248 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PGKGLPEO_00117 1.3e-58 dhaM 2.7.1.121 S PTS system fructose IIA component
PGKGLPEO_00118 1.6e-100 dhaL 2.7.1.121 S Dak2
PGKGLPEO_00119 3.7e-182 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
PGKGLPEO_00120 5.5e-24
PGKGLPEO_00121 6e-149 focA P Formate/nitrite transporter
PGKGLPEO_00122 4.5e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PGKGLPEO_00123 1.9e-116 tcyB P COG0765 ABC-type amino acid transport system, permease component
PGKGLPEO_00124 1.1e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PGKGLPEO_00125 2.9e-167 pip 3.4.11.5, 3.5.1.101 S Releases the N-terminal proline from various substrates
PGKGLPEO_00126 1.7e-84 S Rubrerythrin
PGKGLPEO_00127 6.6e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
PGKGLPEO_00128 1.3e-103 yvbG U UPF0056 membrane protein
PGKGLPEO_00129 4.6e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PGKGLPEO_00130 1.9e-166 yhbB S Putative amidase domain
PGKGLPEO_00131 2.6e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PGKGLPEO_00132 0.0 prkA T Ser protein kinase
PGKGLPEO_00133 9.6e-222 yhbH S Belongs to the UPF0229 family
PGKGLPEO_00135 1.1e-103 2.3.1.128 J Acetyltransferase (GNAT) domain
PGKGLPEO_00136 3.9e-179 pit P phosphate transporter
PGKGLPEO_00137 3.3e-112 ykaA P Protein of unknown function DUF47
PGKGLPEO_00138 4.9e-90 yhcU S Family of unknown function (DUF5365)
PGKGLPEO_00139 2.9e-87 bdbA CO Thioredoxin
PGKGLPEO_00140 3.1e-77 bdbC O Required for disulfide bond formation in some proteins
PGKGLPEO_00141 3.7e-136 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
PGKGLPEO_00142 2.7e-185 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
PGKGLPEO_00143 5.1e-278 ycgB S Stage V sporulation protein R
PGKGLPEO_00145 8.8e-46 yhdB S YhdB-like protein
PGKGLPEO_00146 1.3e-184 corA P Mediates influx of magnesium ions
PGKGLPEO_00147 6.2e-131 S Peptidase C26
PGKGLPEO_00148 7.5e-161 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGKGLPEO_00149 1.4e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGKGLPEO_00150 1.3e-190 dppD P Belongs to the ABC transporter superfamily
PGKGLPEO_00151 0.0 dppE E ABC transporter substrate-binding protein
PGKGLPEO_00152 8.1e-176 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PGKGLPEO_00153 2.6e-191 ykfD E Belongs to the ABC transporter superfamily
PGKGLPEO_00155 4.3e-86 uspF T Universal stress protein
PGKGLPEO_00156 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PGKGLPEO_00157 5.3e-43
PGKGLPEO_00158 1.4e-30 S Protein of unknown function (DUF3006)
PGKGLPEO_00159 8.6e-251 L Metallo-beta-lactamase superfamily
PGKGLPEO_00160 3.5e-07 S Protein of unknown function (DUF1648)
PGKGLPEO_00161 7.6e-52 S Protein of unknown function (DUF1648)
PGKGLPEO_00162 6.3e-14 yjbR S YjbR
PGKGLPEO_00163 6.3e-33 yjbR S YjbR
PGKGLPEO_00164 2.4e-181 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PGKGLPEO_00165 3.1e-292 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
PGKGLPEO_00166 1.3e-204 S Protein of unknown function (DUF917)
PGKGLPEO_00167 1.6e-212 codB F cytosine purines uracil thiamine allantoin
PGKGLPEO_00168 5.4e-289 apc3 3.5.2.9 EQ Hydantoinase oxoprolinase
PGKGLPEO_00169 2e-200 S Protein of unknown function (DUF917)
PGKGLPEO_00170 6.9e-311 K COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PGKGLPEO_00171 3e-84 4.1.2.17, 4.1.2.19 G Class II Aldolase and Adducin N-terminal domain
PGKGLPEO_00172 1.4e-72 2.7.1.11, 2.7.1.56 F pfkB family carbohydrate kinase
PGKGLPEO_00174 2.2e-196 G PTS system sugar-specific permease component
PGKGLPEO_00175 4.1e-30 sgcB 2.7.1.200 G to PTS system galactitol-specific enzyme IIB component
PGKGLPEO_00176 1.2e-35 2.7.1.197, 2.7.1.200, 2.7.1.202 G PTS galactitol transporter subunit IIA
PGKGLPEO_00177 5.8e-158 2.7.1.194, 2.7.1.202 G antiterminator
PGKGLPEO_00178 0.0 gtfC 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PGKGLPEO_00179 1.9e-146 S PD-(D/E)XK nuclease family transposase
PGKGLPEO_00180 5.1e-125 yodH Q Methyltransferase
PGKGLPEO_00181 5.2e-147 yjaZ O Zn-dependent protease
PGKGLPEO_00182 1.9e-29 yodI
PGKGLPEO_00184 4.3e-42 S COG NOG14552 non supervised orthologous group
PGKGLPEO_00185 1.7e-178 tnp4 L Transposase, Mutator family
PGKGLPEO_00186 3.9e-36 csfB S Inhibitor of sigma-G Gin
PGKGLPEO_00187 1.8e-289 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
PGKGLPEO_00188 2e-120 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PGKGLPEO_00189 9.8e-55 yaaQ S protein conserved in bacteria
PGKGLPEO_00190 1.8e-72 yaaR S protein conserved in bacteria
PGKGLPEO_00191 4.3e-186 holB 2.7.7.7 L DNA polymerase III
PGKGLPEO_00192 1.7e-148 yaaT S stage 0 sporulation protein
PGKGLPEO_00193 4.5e-67 yabA L Involved in initiation control of chromosome replication
PGKGLPEO_00194 3.8e-139 yabB 2.1.1.223 S Conserved hypothetical protein 95
PGKGLPEO_00195 1e-47 yazA L endonuclease containing a URI domain
PGKGLPEO_00196 2.7e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PGKGLPEO_00197 1.2e-56 abrB K COG2002 Regulators of stationary sporulation gene expression
PGKGLPEO_00198 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGKGLPEO_00199 1.6e-154 tatD L hydrolase, TatD
PGKGLPEO_00200 8.5e-105 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PGKGLPEO_00201 2.3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PGKGLPEO_00202 8.7e-167 yabG S peptidase
PGKGLPEO_00203 2.4e-37 veg S protein conserved in bacteria
PGKGLPEO_00204 2.2e-34 sspF S DNA topological change
PGKGLPEO_00205 9.2e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PGKGLPEO_00206 6.4e-154 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PGKGLPEO_00207 2.7e-61 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
PGKGLPEO_00208 3.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PGKGLPEO_00210 3.8e-52 S Psort location CytoplasmicMembrane, score
PGKGLPEO_00211 2.7e-73 S Psort location CytoplasmicMembrane, score
PGKGLPEO_00212 2.1e-39 V Abc transporter
PGKGLPEO_00213 1.5e-82
PGKGLPEO_00214 3.5e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PGKGLPEO_00215 3.6e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGKGLPEO_00216 2.4e-110 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PGKGLPEO_00217 9.3e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PGKGLPEO_00218 1.7e-37 yabK S Peptide ABC transporter permease
PGKGLPEO_00219 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PGKGLPEO_00220 1.8e-90 spoVT K stage V sporulation protein
PGKGLPEO_00221 3.8e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGKGLPEO_00222 5.8e-197 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PGKGLPEO_00223 1.1e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PGKGLPEO_00224 4.7e-51 yabP S Sporulation protein YabP
PGKGLPEO_00225 2.4e-110 yabQ S spore cortex biosynthesis protein
PGKGLPEO_00226 1.9e-60 divIC D Septum formation initiator
PGKGLPEO_00227 2.8e-54 yabR J RNA binding protein (contains ribosomal protein S1 domain)
PGKGLPEO_00229 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
PGKGLPEO_00230 2.8e-118 yabS S protein containing a von Willebrand factor type A (vWA) domain
PGKGLPEO_00231 1.5e-159 KLT serine threonine protein kinase
PGKGLPEO_00232 1.2e-277 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PGKGLPEO_00233 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PGKGLPEO_00234 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PGKGLPEO_00235 2.9e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PGKGLPEO_00236 3e-159 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PGKGLPEO_00237 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PGKGLPEO_00238 1.3e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PGKGLPEO_00239 4.2e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PGKGLPEO_00240 1.6e-96 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PGKGLPEO_00241 5.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PGKGLPEO_00242 2.5e-80 K helix_turn_helix multiple antibiotic resistance protein
PGKGLPEO_00243 0.0 yfiB V ABC transporter
PGKGLPEO_00244 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
PGKGLPEO_00245 1e-72
PGKGLPEO_00247 3.9e-245 ybbC 3.2.1.52 S protein conserved in bacteria
PGKGLPEO_00248 0.0 ampC V Belongs to the UPF0214 family
PGKGLPEO_00249 0.0 nagA 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
PGKGLPEO_00250 1.4e-162 ydcZ S Putative inner membrane exporter, YdcZ
PGKGLPEO_00252 7.1e-146 G Major Facilitator Superfamily
PGKGLPEO_00253 1.7e-75 1.14.11.21, 1.14.11.39, 1.14.11.40 C Taurine catabolism dioxygenase TauD, TfdA family
PGKGLPEO_00254 3.5e-74 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGKGLPEO_00255 1.3e-28 cspL K Cold shock
PGKGLPEO_00256 1.5e-217 2.3.1.179 IQ Beta-ketoacyl synthase, C-terminal domain
PGKGLPEO_00257 1.6e-233 2.7.13.3 T His Kinase A (phosphoacceptor) domain
PGKGLPEO_00258 3.5e-09 2.7.13.3 T His Kinase A (phosphoacceptor) domain
PGKGLPEO_00259 1.7e-51
PGKGLPEO_00260 3e-257 G PTS system sugar-specific permease component
PGKGLPEO_00261 4.9e-182 rbsR K transcriptional
PGKGLPEO_00262 6.7e-130 5.1.3.1 G Ribulose-phosphate 3 epimerase family
PGKGLPEO_00263 4.7e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGKGLPEO_00264 0.0 ycnJ P protein, homolog of Cu resistance protein CopC
PGKGLPEO_00265 3.7e-108 ycnI S Domain of unkown function (DUF1775)
PGKGLPEO_00266 5.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PGKGLPEO_00268 9.2e-124 V ATPases associated with a variety of cellular activities
PGKGLPEO_00269 0.0 S FtsX-like permease family
PGKGLPEO_00270 0.0 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PGKGLPEO_00271 1.5e-26 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PGKGLPEO_00272 1.3e-111 kstR2_2 K Transcriptional regulator
PGKGLPEO_00273 3.2e-214 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
PGKGLPEO_00274 3.7e-210 mmgC I acyl-CoA dehydrogenase
PGKGLPEO_00275 4.2e-217 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
PGKGLPEO_00276 0.0 fadF C COG0247 Fe-S oxidoreductase
PGKGLPEO_00277 4.4e-222 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PGKGLPEO_00278 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PGKGLPEO_00279 5.7e-74 ywiB S Domain of unknown function (DUF1934)
PGKGLPEO_00280 4.1e-169 speB 3.5.3.11 E Belongs to the arginase family
PGKGLPEO_00281 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PGKGLPEO_00282 5.4e-92 ywhD S YwhD family
PGKGLPEO_00283 7.3e-118 ywhC S Peptidase M50
PGKGLPEO_00284 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
PGKGLPEO_00285 3.3e-89 ywgA 2.1.1.72, 3.1.21.3
PGKGLPEO_00286 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
PGKGLPEO_00287 6.3e-99 rsfA S Transcriptional regulator
PGKGLPEO_00288 1.5e-59 asp S protein conserved in bacteria
PGKGLPEO_00289 1.5e-305 yloV S kinase related to dihydroxyacetone kinase
PGKGLPEO_00290 7.3e-118 sdaAB 4.3.1.17 E L-serine dehydratase
PGKGLPEO_00291 7.7e-155 sdaAA 4.3.1.17 E L-serine dehydratase
PGKGLPEO_00292 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PGKGLPEO_00293 7.4e-98 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PGKGLPEO_00294 7.8e-208 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PGKGLPEO_00295 4.3e-164 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PGKGLPEO_00296 1.4e-128 IQ reductase
PGKGLPEO_00297 3.7e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGKGLPEO_00298 4.5e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PGKGLPEO_00299 0.0 smc D Required for chromosome condensation and partitioning
PGKGLPEO_00300 5.6e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PGKGLPEO_00301 2.6e-52 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PGKGLPEO_00302 5.1e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PGKGLPEO_00303 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PGKGLPEO_00304 4.7e-35 ylqC S Belongs to the UPF0109 family
PGKGLPEO_00305 8.3e-61 ylqD S YlqD protein
PGKGLPEO_00306 1.7e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PGKGLPEO_00307 8.9e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PGKGLPEO_00308 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PGKGLPEO_00309 1.6e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PGKGLPEO_00310 2.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PGKGLPEO_00311 8.7e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGKGLPEO_00312 2.4e-231 CP_1081 D nuclear chromosome segregation
PGKGLPEO_00313 3.6e-45 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
PGKGLPEO_00314 2.1e-213 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PGKGLPEO_00315 2.8e-168 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PGKGLPEO_00316 6.2e-165 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
PGKGLPEO_00317 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGKGLPEO_00320 5.1e-170 xerC L tyrosine recombinase XerC
PGKGLPEO_00321 2.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PGKGLPEO_00322 2.3e-225 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PGKGLPEO_00323 8.6e-134 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PGKGLPEO_00324 4.4e-62 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PGKGLPEO_00325 4e-75 flgC N Belongs to the flagella basal body rod proteins family
PGKGLPEO_00326 9.9e-41 fliE N Flagellar hook-basal body complex protein FliE
PGKGLPEO_00327 9e-247 fliF N The M ring may be actively involved in energy transduction
PGKGLPEO_00328 2.7e-164 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PGKGLPEO_00329 1.9e-125 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
PGKGLPEO_00330 2e-247 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PGKGLPEO_00331 8.1e-73 fliJ N Flagellar biosynthesis chaperone
PGKGLPEO_00332 9.9e-48 ylxF S MgtE intracellular N domain
PGKGLPEO_00333 1.4e-133 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PGKGLPEO_00334 3.1e-90 yebE S UPF0316 protein
PGKGLPEO_00335 2.9e-31 yebG S NETI protein
PGKGLPEO_00336 3.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PGKGLPEO_00337 5.4e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PGKGLPEO_00338 4.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PGKGLPEO_00339 3.9e-125 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PGKGLPEO_00340 7.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGKGLPEO_00341 3.8e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGKGLPEO_00342 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGKGLPEO_00343 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PGKGLPEO_00344 4.3e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PGKGLPEO_00345 6.4e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PGKGLPEO_00346 2.8e-285 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PGKGLPEO_00347 8.4e-224 purD 6.3.4.13 F Belongs to the GARS family
PGKGLPEO_00348 4.2e-36 S Protein of unknown function (DUF2892)
PGKGLPEO_00349 0.0 yerA 3.5.4.2 F adenine deaminase
PGKGLPEO_00350 3.8e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
PGKGLPEO_00351 1.1e-53 yerC S protein conserved in bacteria
PGKGLPEO_00352 4.7e-131 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PGKGLPEO_00353 9.1e-127 pcrA 3.6.4.12 L AAA domain
PGKGLPEO_00354 5.8e-302 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PGKGLPEO_00355 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PGKGLPEO_00356 1.3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
PGKGLPEO_00357 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
PGKGLPEO_00358 1.8e-245 aceA 4.1.3.1 C Isocitrate lyase
PGKGLPEO_00359 1.5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGKGLPEO_00360 4.2e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PGKGLPEO_00361 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGKGLPEO_00363 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PGKGLPEO_00364 7.7e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PGKGLPEO_00365 2.1e-148
PGKGLPEO_00366 1.7e-235 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PGKGLPEO_00367 4.3e-80 cueR K transcriptional
PGKGLPEO_00368 6.4e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PGKGLPEO_00370 1.2e-299 ywqB S Zinc finger, swim domain protein
PGKGLPEO_00371 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PGKGLPEO_00373 1.6e-70 ywpF S YwpF-like protein
PGKGLPEO_00375 1.3e-63 ssbB L Single-stranded DNA-binding protein
PGKGLPEO_00377 3.5e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PGKGLPEO_00378 5.2e-145 flhP N flagellar basal body
PGKGLPEO_00379 1.4e-144 flhO N flagellar basal body
PGKGLPEO_00380 1.7e-179 mbl D Rod shape-determining protein
PGKGLPEO_00381 1.3e-41 spoIIID K Stage III sporulation protein D
PGKGLPEO_00382 2.9e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
PGKGLPEO_00383 3.4e-183 spoIID D Stage II sporulation protein D
PGKGLPEO_00384 8.8e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGKGLPEO_00385 5.7e-135 ywmB S TATA-box binding
PGKGLPEO_00386 1.4e-34 ywzB S membrane
PGKGLPEO_00387 6.3e-59 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PGKGLPEO_00388 2.7e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PGKGLPEO_00389 5e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PGKGLPEO_00390 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PGKGLPEO_00391 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGKGLPEO_00392 1e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PGKGLPEO_00393 1.3e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGKGLPEO_00394 8.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
PGKGLPEO_00395 4.1e-57 atpI S ATP synthase I chain
PGKGLPEO_00396 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PGKGLPEO_00397 1.1e-239 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PGKGLPEO_00398 7.2e-98 ywlG S Belongs to the UPF0340 family
PGKGLPEO_00399 1.4e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
PGKGLPEO_00400 8.8e-176 mcpA NT Chemotaxis
PGKGLPEO_00401 2.4e-80 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGKGLPEO_00402 3.7e-91 mntP P Probably functions as a manganese efflux pump
PGKGLPEO_00403 6.3e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PGKGLPEO_00404 7.4e-122 spoIIR S stage II sporulation protein R
PGKGLPEO_00405 1.3e-162 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PGKGLPEO_00406 6.6e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PGKGLPEO_00407 5.3e-07
PGKGLPEO_00408 1.7e-110 tdk 2.7.1.21 F thymidine kinase
PGKGLPEO_00409 2.2e-33 rpmE J Ribosomal protein L31
PGKGLPEO_00410 7.8e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PGKGLPEO_00411 7.8e-177 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
PGKGLPEO_00412 5.6e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGKGLPEO_00413 4.4e-115 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PGKGLPEO_00414 3.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
PGKGLPEO_00415 6e-61 spo0F T response regulator
PGKGLPEO_00416 2.5e-206
PGKGLPEO_00417 8.9e-145
PGKGLPEO_00418 4.6e-123 yhcG V ABC transporter, ATP-binding protein
PGKGLPEO_00419 1e-66 K helix_turn_helix gluconate operon transcriptional repressor
PGKGLPEO_00420 5.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PGKGLPEO_00422 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PGKGLPEO_00423 0.0 metH 2.1.1.13 E Methionine synthase
PGKGLPEO_00424 3.4e-12 csbD S Belongs to the UPF0337 (CsbD) family
PGKGLPEO_00425 1.1e-83 K ComK protein
PGKGLPEO_00426 1.5e-101 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
PGKGLPEO_00427 2.2e-148 E lipolytic protein G-D-S-L family
PGKGLPEO_00428 6.3e-118 ywqC M biosynthesis protein
PGKGLPEO_00429 1.2e-107 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
PGKGLPEO_00430 2.3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
PGKGLPEO_00431 2e-155 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PGKGLPEO_00432 5.1e-93 cpsE M Bacterial sugar transferase
PGKGLPEO_00433 7.5e-82 wzx M Polysaccharide biosynthesis protein
PGKGLPEO_00434 8.7e-47 M Glycosyl transferases group 1
PGKGLPEO_00435 3.2e-36 GT4 M Glycosyltransferase Family 4
PGKGLPEO_00436 5.1e-12
PGKGLPEO_00437 4e-97 2.4.1.21 GT4,GT5 G Glycosyl transferase 4-like
PGKGLPEO_00438 6.5e-177 manC 2.7.7.13, 5.3.1.8 G mannose-1-phosphate guanylyltransferase
PGKGLPEO_00440 7.6e-234 L Mu transposase, C-terminal
PGKGLPEO_00441 2e-130 U COG3267 Type II secretory pathway, component ExeA
PGKGLPEO_00442 7.7e-129 U AAA domain
PGKGLPEO_00443 9.8e-09 S Domain of unknown function (DUF5348)
PGKGLPEO_00444 2.4e-114 K Transcriptional regulator
PGKGLPEO_00445 3.3e-222 garD 4.2.1.42, 4.2.1.7 G D-galactarate dehydratase altronate hydrolase
PGKGLPEO_00446 3.3e-93 KT regulator
PGKGLPEO_00447 1.7e-101 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGKGLPEO_00448 7e-136 gntT EG COG2610 H gluconate symporter and related permeases
PGKGLPEO_00449 6.1e-144 garR 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PGKGLPEO_00450 1.3e-233 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PGKGLPEO_00451 2.6e-155 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PGKGLPEO_00452 7.5e-197 xylP G COGs COG2211 Na melibiose symporter and related transporter
PGKGLPEO_00453 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
PGKGLPEO_00454 5.4e-116 xylR GK Transcriptional regulator
PGKGLPEO_00455 3.4e-146 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
PGKGLPEO_00456 4.3e-109 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
PGKGLPEO_00457 3.1e-109 P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
PGKGLPEO_00458 8.1e-137 K Propionate catabolism activator
PGKGLPEO_00459 2.1e-144 fba 4.1.2.13 G Fructose-bisphosphate aldolase class-II
PGKGLPEO_00460 1e-124 4.1.2.13 G Fructose-bisphosphate aldolase class-II
PGKGLPEO_00461 4.9e-127 P PTS fructose transporter subunit IIC
PGKGLPEO_00462 2.7e-41 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
PGKGLPEO_00463 1.2e-56 frvA 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PGKGLPEO_00464 1.5e-161 K DeoR-like helix-turn-helix domain
PGKGLPEO_00465 3.2e-16 atzF 3.5.1.4, 3.5.1.54 J Amidase
PGKGLPEO_00466 5e-19 atzF 3.5.1.4, 3.5.1.54 J Amidase
PGKGLPEO_00467 8.7e-70 atzF 3.5.1.4, 3.5.1.54 J Amidase
PGKGLPEO_00468 9.1e-42 agaD G PTS system mannose/fructose/sorbose family IID component
PGKGLPEO_00470 1.3e-12 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PGKGLPEO_00471 1.1e-54
PGKGLPEO_00472 6.6e-76 yoaS S Protein of unknown function (DUF2975)
PGKGLPEO_00473 1.2e-29 yozG K Transcriptional regulator
PGKGLPEO_00474 3.3e-155 yoaT S Protein of unknown function (DUF817)
PGKGLPEO_00475 1.9e-194 NT chemotaxis protein
PGKGLPEO_00477 5.5e-86
PGKGLPEO_00478 2e-252 S Protein of unknown function N-terminus (DUF3323)
PGKGLPEO_00479 0.0 D Putative exonuclease SbcCD, C subunit
PGKGLPEO_00480 1.6e-229 S Protein of unknown function (DUF2398)
PGKGLPEO_00481 3.4e-264 S Protein of unknown function (DUF2397)
PGKGLPEO_00482 1.6e-281 yhgE S YhgE Pip N-terminal domain protein
PGKGLPEO_00483 7.4e-106 yhgD K Transcriptional regulator
PGKGLPEO_00484 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
PGKGLPEO_00486 1.8e-195 ansA 3.5.1.1 EJ L-asparaginase
PGKGLPEO_00487 7.2e-217 xylR GK ROK family
PGKGLPEO_00488 2.2e-204 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PGKGLPEO_00489 9e-153 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
PGKGLPEO_00490 1.2e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
PGKGLPEO_00491 1.1e-203 nifS 2.8.1.7 E Cysteine desulfurase
PGKGLPEO_00492 3.2e-95 S NYN domain
PGKGLPEO_00493 3.5e-143 focA P Formate nitrite
PGKGLPEO_00494 4.9e-264 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PGKGLPEO_00495 7.6e-144 cbiQ P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
PGKGLPEO_00496 0.0 ykoD P ABC transporter, ATP-binding protein
PGKGLPEO_00497 1.3e-91 S UPF0397 protein
PGKGLPEO_00498 3.3e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
PGKGLPEO_00499 7e-120 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PGKGLPEO_00500 5.8e-253 EG COG2610 H gluconate symporter and related permeases
PGKGLPEO_00501 2.4e-278 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGKGLPEO_00502 7.8e-219 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
PGKGLPEO_00503 0.0 KT Transcriptional regulator
PGKGLPEO_00504 0.0 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
PGKGLPEO_00505 1.5e-15 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
PGKGLPEO_00506 1.2e-279 Otg1 S Predicted membrane protein (DUF2339)
PGKGLPEO_00507 4e-228 1.3.8.7 I Acyl-CoA dehydrogenase, N-terminal domain
PGKGLPEO_00508 2.1e-277 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PGKGLPEO_00509 3.2e-194 S Metallo-beta-lactamase superfamily
PGKGLPEO_00510 8.2e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PGKGLPEO_00511 2.3e-134 phnE 3.6.1.63 P ABC transporter
PGKGLPEO_00512 6.1e-143 phnE 3.6.1.63 P ABC transporter
PGKGLPEO_00513 7.9e-174 phnD P Phosphonate ABC transporter
PGKGLPEO_00514 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PGKGLPEO_00515 2.1e-207 ysdC G COG1363 Cellulase M and related proteins
PGKGLPEO_00517 6.8e-44
PGKGLPEO_00518 6.2e-52 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PGKGLPEO_00519 2e-103
PGKGLPEO_00520 5.6e-30 P Heavy-metal-associated domain
PGKGLPEO_00521 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
PGKGLPEO_00522 1.5e-138 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PGKGLPEO_00523 3.8e-204 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PGKGLPEO_00524 1.7e-81 fld C Flavodoxin
PGKGLPEO_00526 2.7e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
PGKGLPEO_00527 2.2e-125 gntR K transcriptional
PGKGLPEO_00528 1.1e-308 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
PGKGLPEO_00529 2.4e-229 EG COG2610 H gluconate symporter and related permeases
PGKGLPEO_00530 2.2e-131 treR K transcriptional
PGKGLPEO_00531 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PGKGLPEO_00532 1e-265 treP 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PGKGLPEO_00533 2.8e-82 2.7.1.199 G COG2190 Phosphotransferase system IIA components
PGKGLPEO_00534 4.1e-273 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
PGKGLPEO_00535 5.5e-175 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PGKGLPEO_00537 1.4e-155 Q N-acetyltransferase
PGKGLPEO_00538 4.2e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PGKGLPEO_00539 1e-268 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGKGLPEO_00540 2.2e-265 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGKGLPEO_00541 3.5e-17 yxjI S LURP-one-related
PGKGLPEO_00542 4.1e-38 yxjI S LURP-one-related
PGKGLPEO_00543 1.2e-191
PGKGLPEO_00544 5.7e-94 S S4 RNA-binding domain
PGKGLPEO_00545 1e-53 3.5.1.19 Q Isochorismatase family
PGKGLPEO_00547 3.6e-199 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PGKGLPEO_00548 9.4e-183 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PGKGLPEO_00549 9.8e-269 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PGKGLPEO_00550 6.4e-102 yhgD K Transcriptional regulator
PGKGLPEO_00551 4.4e-222 yhgE S YhgE Pip N-terminal domain protein
PGKGLPEO_00552 8.3e-179 arbF1 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
PGKGLPEO_00553 2.3e-142 ydjF K DeoR C terminal sensor domain
PGKGLPEO_00554 5.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
PGKGLPEO_00555 5.6e-242 iolF EGP Major facilitator Superfamily
PGKGLPEO_00556 8.1e-166 EG EamA-like transporter family
PGKGLPEO_00557 3.7e-271 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGKGLPEO_00558 1.1e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PGKGLPEO_00559 3.6e-64 ytkA S YtkA-like
PGKGLPEO_00560 3e-21 yhfH S YhfH-like protein
PGKGLPEO_00561 3.2e-186 lplJ 6.3.1.20 H Lipoate-protein ligase
PGKGLPEO_00562 3.2e-297 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
PGKGLPEO_00563 2e-121 azlC E AzlC protein
PGKGLPEO_00564 3.9e-42 azlD S branched-chain amino acid
PGKGLPEO_00565 1.9e-220 yhfN 3.4.24.84 O Peptidase M48
PGKGLPEO_00566 3.4e-09 S IDEAL
PGKGLPEO_00567 2.6e-97 comK K Competence transcription factor
PGKGLPEO_00568 1.7e-145 S Mitochondrial biogenesis AIM24
PGKGLPEO_00570 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
PGKGLPEO_00571 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PGKGLPEO_00572 4.2e-30 gerPF S Spore germination protein gerPA/gerPF
PGKGLPEO_00573 3.4e-71 gerPE S Spore germination protein GerPE
PGKGLPEO_00574 2e-25 gerPD S Spore germination protein
PGKGLPEO_00575 1.2e-98 gerPC S Spore germination protein
PGKGLPEO_00576 1.6e-32 gerPA S Spore germination protein
PGKGLPEO_00577 4.3e-222 P Protein of unknown function (DUF418)
PGKGLPEO_00578 2.4e-164 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PGKGLPEO_00579 5.1e-60 yisL S UPF0344 protein
PGKGLPEO_00580 9.3e-106 yisN S Protein of unknown function (DUF2777)
PGKGLPEO_00581 3.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_00582 1.9e-158 yitS S protein conserved in bacteria
PGKGLPEO_00583 5.7e-26 S Protein of unknown function (DUF3813)
PGKGLPEO_00584 2.5e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PGKGLPEO_00585 9.5e-52 yitW S metal-sulfur cluster biosynthetic enzyme
PGKGLPEO_00586 6.2e-27 yjzC S YjzC-like protein
PGKGLPEO_00587 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PGKGLPEO_00589 8.4e-142 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
PGKGLPEO_00591 1.9e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGKGLPEO_00592 7.3e-236 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PGKGLPEO_00593 2.4e-152 yjaZ O Zn-dependent protease
PGKGLPEO_00594 6.8e-195 oppD P Belongs to the ABC transporter superfamily
PGKGLPEO_00595 7.5e-177 oppF P Belongs to the ABC transporter superfamily
PGKGLPEO_00596 4e-173 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGKGLPEO_00597 5.9e-134 oppC EP binding-protein-dependent transport systems inner membrane component
PGKGLPEO_00598 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
PGKGLPEO_00599 1.1e-101 yieF S NAD(P)H-dependent FMN reductase
PGKGLPEO_00600 2.6e-122 mcpB3 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PGKGLPEO_00601 1.2e-180 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PGKGLPEO_00602 5e-95 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGKGLPEO_00603 7.4e-269 M O-Antigen ligase
PGKGLPEO_00604 1.9e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PGKGLPEO_00606 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PGKGLPEO_00607 3.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PGKGLPEO_00608 4.5e-112 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PGKGLPEO_00609 1.7e-219 G Transmembrane secretion effector
PGKGLPEO_00610 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGKGLPEO_00611 4e-153 ytxC S YtxC-like family
PGKGLPEO_00612 9e-178 dnaI L Primosomal protein DnaI
PGKGLPEO_00613 2.8e-260 dnaB L Membrane attachment protein
PGKGLPEO_00614 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PGKGLPEO_00615 4.9e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PGKGLPEO_00616 7.9e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGKGLPEO_00617 1.6e-109 ytaF P Probably functions as a manganese efflux pump
PGKGLPEO_00618 2.3e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PGKGLPEO_00619 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGKGLPEO_00620 6.8e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
PGKGLPEO_00621 4e-245 icd 1.1.1.42 C isocitrate
PGKGLPEO_00622 3.4e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
PGKGLPEO_00623 1e-73 yeaL S Membrane
PGKGLPEO_00624 8.5e-159 ytvI S sporulation integral membrane protein YtvI
PGKGLPEO_00625 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PGKGLPEO_00626 3e-176 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PGKGLPEO_00627 4.2e-178 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PGKGLPEO_00628 2e-163 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PGKGLPEO_00629 1.5e-228 ytsJ 1.1.1.38 C Malate dehydrogenase
PGKGLPEO_00630 0.0 dnaE 2.7.7.7 L DNA polymerase
PGKGLPEO_00631 1.6e-41 ytrH S Sporulation protein YtrH
PGKGLPEO_00632 4.2e-89 ytrI
PGKGLPEO_00633 1.4e-178 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
PGKGLPEO_00634 1.9e-44 ytpI S YtpI-like protein
PGKGLPEO_00635 8e-241 ytoI K transcriptional regulator containing CBS domains
PGKGLPEO_00636 1.5e-129 ytkL S Belongs to the UPF0173 family
PGKGLPEO_00637 5.5e-179 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PGKGLPEO_00638 1.7e-196 ald 1.4.1.1 E Belongs to the AlaDH PNT family
PGKGLPEO_00639 3.1e-78 uspA T Belongs to the universal stress protein A family
PGKGLPEO_00640 3.6e-154 S EcsC protein family
PGKGLPEO_00641 2e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PGKGLPEO_00642 1.8e-184 ytxK 2.1.1.72 L DNA methylase
PGKGLPEO_00643 5.8e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PGKGLPEO_00644 5.8e-69 ytfJ S Sporulation protein YtfJ
PGKGLPEO_00645 4.8e-117 ytfI S Protein of unknown function (DUF2953)
PGKGLPEO_00646 3.3e-89 yteJ S RDD family
PGKGLPEO_00647 1.4e-184 sppA OU signal peptide peptidase SppA
PGKGLPEO_00648 8.2e-309 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PGKGLPEO_00649 1.4e-27 sspB S spore protein
PGKGLPEO_00650 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGKGLPEO_00651 6.8e-212 iscS2 2.8.1.7 E Cysteine desulfurase
PGKGLPEO_00652 1.7e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PGKGLPEO_00653 4.6e-117 yttP K Transcriptional regulator
PGKGLPEO_00654 5.4e-86 ytsP 1.8.4.14 T GAF domain-containing protein
PGKGLPEO_00655 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
PGKGLPEO_00656 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PGKGLPEO_00657 1.1e-181 putA E Proline dehydrogenase
PGKGLPEO_00658 2.4e-297 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PGKGLPEO_00659 7.3e-253 prdR KT Transcriptional regulator
PGKGLPEO_00660 1.1e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PGKGLPEO_00661 3.3e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PGKGLPEO_00662 7.3e-208 crtQ M Glycosyl transferase family 21
PGKGLPEO_00663 8.9e-110 plsY 2.3.1.15 I Belongs to the PlsY family
PGKGLPEO_00664 4e-195 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGKGLPEO_00665 1.6e-87 fld C Flavodoxin
PGKGLPEO_00666 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGKGLPEO_00668 0.0
PGKGLPEO_00669 2.3e-130 dnaD L DNA replication protein DnaD
PGKGLPEO_00670 2.6e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PGKGLPEO_00671 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PGKGLPEO_00672 1.9e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PGKGLPEO_00676 7e-62 yppE S Bacterial domain of unknown function (DUF1798)
PGKGLPEO_00677 2.9e-71 yppG S YppG-like protein
PGKGLPEO_00678 4.2e-77 hspX O Belongs to the small heat shock protein (HSP20) family
PGKGLPEO_00679 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PGKGLPEO_00680 5.1e-256 yprB L RNase_H superfamily
PGKGLPEO_00681 8.3e-46 cotD S Inner spore coat protein D
PGKGLPEO_00682 1.4e-101 ypsA S Belongs to the UPF0398 family
PGKGLPEO_00683 9e-47 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PGKGLPEO_00684 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PGKGLPEO_00685 1.8e-300 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PGKGLPEO_00686 2.5e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PGKGLPEO_00687 1.2e-233 pbuX F xanthine
PGKGLPEO_00688 1.3e-131 f42a O prohibitin homologues
PGKGLPEO_00689 2.6e-34
PGKGLPEO_00690 0.0 S Dynamin family
PGKGLPEO_00691 2.8e-64 glnR K transcriptional
PGKGLPEO_00692 4.4e-263 glnA 6.3.1.2 E glutamine synthetase
PGKGLPEO_00693 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PGKGLPEO_00694 4.1e-56 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PGKGLPEO_00695 8.9e-116 yneB L resolvase
PGKGLPEO_00696 3e-18 ynzC S UPF0291 protein
PGKGLPEO_00697 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGKGLPEO_00698 4.2e-77 yneE S Sporulation inhibitor of replication protein sirA
PGKGLPEO_00699 6.8e-28 yneF S UPF0154 protein
PGKGLPEO_00700 1.5e-177 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGKGLPEO_00701 6.7e-127 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PGKGLPEO_00702 2.3e-11 S NADPH-dependent FMN reductase
PGKGLPEO_00703 1.8e-56 K Transcriptional regulator
PGKGLPEO_00704 6.1e-123 M1-1017 S Protein of unknown function (DUF1129)
PGKGLPEO_00705 6.3e-57 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PGKGLPEO_00706 1.4e-41
PGKGLPEO_00707 8.2e-133 S Domain of unknown function (DUF4405)
PGKGLPEO_00708 1.3e-232 L COG3547 Transposase and inactivated derivatives
PGKGLPEO_00709 7.9e-260 L Transposase
PGKGLPEO_00710 5.2e-59
PGKGLPEO_00711 2.9e-31 sspI S Belongs to the SspI family
PGKGLPEO_00712 4.7e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGKGLPEO_00713 2.8e-180 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PGKGLPEO_00714 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGKGLPEO_00715 1.4e-86 V Mate efflux family protein
PGKGLPEO_00716 2.2e-46 KT Transcriptional
PGKGLPEO_00717 6e-166 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGKGLPEO_00718 7.3e-46 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PGKGLPEO_00719 4.9e-88 cvpA S membrane protein, required for colicin V production
PGKGLPEO_00720 0.0 polX L COG1796 DNA polymerase IV (family X)
PGKGLPEO_00721 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PGKGLPEO_00722 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGKGLPEO_00723 1.6e-103 fadR K Transcriptional regulator
PGKGLPEO_00724 1.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PGKGLPEO_00725 2.4e-128 etfB C Electron transfer flavoprotein
PGKGLPEO_00726 1.1e-173 etfA C Electron transfer flavoprotein
PGKGLPEO_00727 6.7e-53 trxA O Belongs to the thioredoxin family
PGKGLPEO_00728 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PGKGLPEO_00729 5.6e-220 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PGKGLPEO_00730 1.7e-81 yslB S Protein of unknown function (DUF2507)
PGKGLPEO_00731 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PGKGLPEO_00732 1.3e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PGKGLPEO_00733 6.7e-89 ysmA S thioesterase
PGKGLPEO_00734 2.3e-31 gerE K Transcriptional regulator
PGKGLPEO_00736 2.5e-195 S Predicted membrane protein (DUF2157)
PGKGLPEO_00737 1.4e-92 S GDYXXLXY protein
PGKGLPEO_00738 2.7e-79 ysmB 2.4.2.28 K transcriptional
PGKGLPEO_00739 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PGKGLPEO_00740 1.3e-31 yraG S Spore Coat Protein
PGKGLPEO_00741 1.6e-61 yraF M Spore coat protein
PGKGLPEO_00742 6.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PGKGLPEO_00743 2.6e-46 M Spore coat protein
PGKGLPEO_00744 4.3e-13
PGKGLPEO_00745 7.8e-191 gerM S COG5401 Spore germination protein
PGKGLPEO_00746 1.6e-106 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PGKGLPEO_00747 2.8e-93 ysnB S Phosphoesterase
PGKGLPEO_00749 3.4e-46
PGKGLPEO_00750 1.4e-72 S Protein of unknown function (DUF2512)
PGKGLPEO_00751 9.8e-183 S chaperone-mediated protein folding
PGKGLPEO_00752 4.3e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PGKGLPEO_00753 1.7e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PGKGLPEO_00754 2.2e-309 lonB 3.4.21.53 LO Belongs to the peptidase S16 family
PGKGLPEO_00755 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PGKGLPEO_00756 4.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
PGKGLPEO_00757 4.5e-88 ysxD
PGKGLPEO_00758 1.2e-241 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PGKGLPEO_00759 7.7e-149 hemX O cytochrome C
PGKGLPEO_00760 2.1e-166 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PGKGLPEO_00761 2.3e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PGKGLPEO_00762 7.1e-186 hemB 4.2.1.24 H Belongs to the ALAD family
PGKGLPEO_00763 3.5e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PGKGLPEO_00764 2.3e-193 spoVID M stage VI sporulation protein D
PGKGLPEO_00765 1.6e-227 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PGKGLPEO_00766 9.5e-26
PGKGLPEO_00767 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PGKGLPEO_00768 8.3e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PGKGLPEO_00771 7.3e-100
PGKGLPEO_00772 1.2e-140 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PGKGLPEO_00773 3.7e-166 spoIIB
PGKGLPEO_00775 1.3e-122 radC E Belongs to the UPF0758 family
PGKGLPEO_00776 5.3e-184 mreB D Rod shape-determining protein MreB
PGKGLPEO_00777 2.9e-138 mreC M Involved in formation and maintenance of cell shape
PGKGLPEO_00778 9e-87 mreD M shape-determining protein
PGKGLPEO_00779 4.1e-119 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PGKGLPEO_00780 3.3e-144 minD D Belongs to the ParA family
PGKGLPEO_00781 1.5e-135 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
PGKGLPEO_00782 9.8e-163 spoIVFB S Stage IV sporulation protein
PGKGLPEO_00783 2.9e-279 rng J ribonuclease, Rne Rng family
PGKGLPEO_00784 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
PGKGLPEO_00785 3.5e-52 ysxB J ribosomal protein
PGKGLPEO_00786 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PGKGLPEO_00787 3e-98 spo0B T Sporulation initiation phospho-transferase B, C-terminal
PGKGLPEO_00788 9.9e-244 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PGKGLPEO_00789 1.2e-74 pheB 5.4.99.5 S Belongs to the UPF0735 family
PGKGLPEO_00790 1.1e-158 pheA 4.2.1.51 E Prephenate dehydratase
PGKGLPEO_00791 3.9e-96 niaR S small molecule binding protein (contains 3H domain)
PGKGLPEO_00792 1.8e-133 safA M spore coat assembly protein SafA
PGKGLPEO_00793 8.9e-189 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
PGKGLPEO_00794 5e-128 yebC K transcriptional regulatory protein
PGKGLPEO_00795 7.2e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PGKGLPEO_00796 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PGKGLPEO_00797 3.2e-27 yrzS S Protein of unknown function (DUF2905)
PGKGLPEO_00798 3.7e-193 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PGKGLPEO_00799 5.3e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PGKGLPEO_00800 8.7e-51 yajC U Preprotein translocase subunit YajC
PGKGLPEO_00801 1.4e-63 yrzE S Protein of unknown function (DUF3792)
PGKGLPEO_00802 9.5e-110 yrbG S membrane
PGKGLPEO_00803 4.5e-275 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGKGLPEO_00804 1.2e-54 yrzD S Post-transcriptional regulator
PGKGLPEO_00805 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PGKGLPEO_00806 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PGKGLPEO_00807 9e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PGKGLPEO_00808 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PGKGLPEO_00809 1.6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PGKGLPEO_00810 2e-71 K helix_turn_helix multiple antibiotic resistance protein
PGKGLPEO_00811 1.2e-107 emrA V Barrel-sandwich domain of CusB or HlyD membrane-fusion
PGKGLPEO_00812 0.0 yhcA5 EGP Major facilitator Superfamily
PGKGLPEO_00813 2.2e-263 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
PGKGLPEO_00815 2e-249 hisS 6.1.1.21 J histidyl-tRNA synthetase
PGKGLPEO_00816 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PGKGLPEO_00818 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
PGKGLPEO_00819 5.3e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PGKGLPEO_00820 4.4e-236 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PGKGLPEO_00821 8.8e-136 IQ Short-chain dehydrogenase reductase sdr
PGKGLPEO_00822 1.5e-26
PGKGLPEO_00823 6.6e-72 cymR K Transcriptional regulator
PGKGLPEO_00824 9.8e-211 iscS 2.8.1.7 E Cysteine desulfurase
PGKGLPEO_00825 6.4e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PGKGLPEO_00826 7.7e-123 S COG0457 FOG TPR repeat
PGKGLPEO_00827 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PGKGLPEO_00828 1.2e-191 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
PGKGLPEO_00829 1.3e-152 bkdB 1.8.1.4, 2.3.1.12, 2.3.1.168 C 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
PGKGLPEO_00830 4.5e-159 pdhB 1.2.4.1 C Transketolase, C-terminal domain
PGKGLPEO_00831 9.5e-168 bkdA1 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PGKGLPEO_00832 9.2e-177 pdh 1.4.1.20, 1.4.1.9 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
PGKGLPEO_00833 2.5e-30 K helix_turn_helix ASNC type
PGKGLPEO_00834 4.2e-68 yndM S Protein of unknown function (DUF2512)
PGKGLPEO_00835 1.8e-29 yrzR
PGKGLPEO_00837 1.1e-174 yrrI S AI-2E family transporter
PGKGLPEO_00838 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGKGLPEO_00839 5.8e-45 yrzL S Belongs to the UPF0297 family
PGKGLPEO_00840 8.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PGKGLPEO_00841 1.5e-41 yrzB S Belongs to the UPF0473 family
PGKGLPEO_00842 1.1e-203 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PGKGLPEO_00843 2.8e-114 yrrM 2.1.1.104 S O-methyltransferase
PGKGLPEO_00844 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PGKGLPEO_00845 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PGKGLPEO_00846 5.5e-59 yrrS S Protein of unknown function (DUF1510)
PGKGLPEO_00847 1.2e-29 yrzA S Protein of unknown function (DUF2536)
PGKGLPEO_00848 1.2e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PGKGLPEO_00849 1.7e-10 S YrhC-like protein
PGKGLPEO_00851 3.8e-107 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
PGKGLPEO_00852 1.2e-291 ahpF O Alkyl hydroperoxide reductase
PGKGLPEO_00853 2.1e-126 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGKGLPEO_00854 5.1e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGKGLPEO_00855 4.2e-15 sda S Sporulation inhibitor A
PGKGLPEO_00856 1.2e-150 czcD P COG1230 Co Zn Cd efflux system component
PGKGLPEO_00857 9.1e-119 S VIT family
PGKGLPEO_00858 1.5e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGKGLPEO_00859 4.3e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGKGLPEO_00860 5.1e-75 lemA S LemA family
PGKGLPEO_00861 2.9e-105 S TPM domain
PGKGLPEO_00862 3.1e-107 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PGKGLPEO_00863 5.4e-23 S Short C-terminal domain
PGKGLPEO_00864 3.9e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
PGKGLPEO_00865 4.2e-236 mco 1.16.3.3 Q multicopper oxidases
PGKGLPEO_00866 2.5e-18 S Short C-terminal domain
PGKGLPEO_00867 0.0 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PGKGLPEO_00868 8.2e-55 P Rhodanese Homology Domain
PGKGLPEO_00869 5.3e-39 O Glutaredoxin
PGKGLPEO_00870 7.8e-67 perX S DsrE/DsrF-like family
PGKGLPEO_00871 1.8e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
PGKGLPEO_00872 1.9e-280 mco 1.16.3.3 Q multicopper oxidases
PGKGLPEO_00873 6.7e-193 ysfB KT regulator
PGKGLPEO_00874 3.9e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
PGKGLPEO_00875 3.9e-259 glcF C Glycolate oxidase
PGKGLPEO_00876 1.3e-93 yqeG S hydrolase of the HAD superfamily
PGKGLPEO_00877 7e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PGKGLPEO_00878 9.2e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PGKGLPEO_00879 8.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
PGKGLPEO_00880 1.9e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PGKGLPEO_00881 1.8e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PGKGLPEO_00882 2.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PGKGLPEO_00883 8.5e-147 cmoA S Methyltransferase domain
PGKGLPEO_00884 2.6e-149 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGKGLPEO_00885 4e-85 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PGKGLPEO_00886 6.5e-113 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
PGKGLPEO_00887 0.0 comEC S Competence protein ComEC
PGKGLPEO_00888 3.1e-07 S YqzM-like protein
PGKGLPEO_00889 1.4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
PGKGLPEO_00890 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
PGKGLPEO_00891 1.7e-199 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PGKGLPEO_00892 1.6e-224 spoIIP M stage II sporulation protein P
PGKGLPEO_00893 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PGKGLPEO_00894 1.4e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
PGKGLPEO_00895 3.2e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PGKGLPEO_00896 1.3e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PGKGLPEO_00897 2.5e-309 dnaK O Heat shock 70 kDa protein
PGKGLPEO_00898 3.2e-206 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PGKGLPEO_00899 8.1e-171 prmA J Methylates ribosomal protein L11
PGKGLPEO_00900 1.4e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PGKGLPEO_00901 2.7e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
PGKGLPEO_00902 6.1e-155 yqeW P COG1283 Na phosphate symporter
PGKGLPEO_00903 2.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PGKGLPEO_00904 9.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PGKGLPEO_00905 5.4e-72 yqeY S Yqey-like protein
PGKGLPEO_00906 3.2e-46 yqfC S sporulation protein YqfC
PGKGLPEO_00907 6.6e-226 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
PGKGLPEO_00908 5.2e-173 phoH T Phosphate starvation-inducible protein PhoH
PGKGLPEO_00909 0.0 yqfF S membrane-associated HD superfamily hydrolase
PGKGLPEO_00910 2.7e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PGKGLPEO_00911 3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PGKGLPEO_00912 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PGKGLPEO_00913 3e-08 S YqzL-like protein
PGKGLPEO_00914 1.1e-144 recO L Involved in DNA repair and RecF pathway recombination
PGKGLPEO_00915 4.5e-112 ccpN K CBS domain
PGKGLPEO_00916 1.8e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PGKGLPEO_00917 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PGKGLPEO_00918 2e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PGKGLPEO_00919 3.4e-89
PGKGLPEO_00920 5.8e-64 cccA C Cytochrome C oxidase, cbb3-type, subunit III
PGKGLPEO_00921 3.9e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
PGKGLPEO_00922 2.5e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PGKGLPEO_00923 5.8e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PGKGLPEO_00926 3.9e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PGKGLPEO_00927 6.6e-170 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PGKGLPEO_00928 4.9e-124 usp CBM50 M protein conserved in bacteria
PGKGLPEO_00929 1.3e-19 yqfT S Protein of unknown function (DUF2624)
PGKGLPEO_00930 2.9e-142 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PGKGLPEO_00931 1.8e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PGKGLPEO_00932 3.8e-75 zur P Belongs to the Fur family
PGKGLPEO_00933 4.9e-113 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
PGKGLPEO_00934 7.3e-203 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PGKGLPEO_00935 9.9e-55 fimV NU Tfp pilus assembly protein FimV
PGKGLPEO_00936 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
PGKGLPEO_00937 7.3e-193 bktB 2.3.1.9 I Belongs to the thiolase family
PGKGLPEO_00938 1.1e-252 ydiF 2.8.3.1 I Coenzyme A transferase
PGKGLPEO_00939 6.4e-126 G Uncharacterised MFS-type transporter YbfB
PGKGLPEO_00940 1.3e-103 G transmembrane transporter activity
PGKGLPEO_00941 2e-95 y2-aiiA 3.1.1.81 GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGKGLPEO_00942 2.4e-191 2.8.3.1 I Belongs to the 3-oxoacid CoA-transferase family
PGKGLPEO_00943 1.5e-106 IQ Enoyl-(Acyl carrier protein) reductase
PGKGLPEO_00944 5.7e-101 K transcriptional
PGKGLPEO_00945 3.2e-107 E Lysine exporter protein LysE YggA
PGKGLPEO_00946 2.7e-123 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
PGKGLPEO_00947 2.9e-176 yvdE K Transcriptional regulator
PGKGLPEO_00948 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
PGKGLPEO_00949 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
PGKGLPEO_00950 7.7e-241 mdxE G COG2182 Maltose-binding periplasmic proteins domains
PGKGLPEO_00951 1.8e-240 malC P COG1175 ABC-type sugar transport systems, permease components
PGKGLPEO_00952 8.7e-156 malD P transport
PGKGLPEO_00953 7.3e-147 malA S Protein of unknown function (DUF1189)
PGKGLPEO_00954 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
PGKGLPEO_00955 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
PGKGLPEO_00957 1.3e-190 adhP 1.1.1.1 C alcohol dehydrogenase
PGKGLPEO_00958 4.2e-40 S Nucleotidyltransferase domain
PGKGLPEO_00959 9e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
PGKGLPEO_00960 2.2e-113 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
PGKGLPEO_00961 9e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
PGKGLPEO_00962 5.7e-129 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
PGKGLPEO_00963 4.5e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PGKGLPEO_00964 8.9e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PGKGLPEO_00965 0.0 ydiF S ABC transporter
PGKGLPEO_00966 1.6e-08 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PGKGLPEO_00967 2.7e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PGKGLPEO_00968 5.1e-131 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PGKGLPEO_00969 1.3e-27 S Domain of unknown function (DUF4305)
PGKGLPEO_00970 8.1e-126 ydiL S CAAX protease self-immunity
PGKGLPEO_00971 9.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PGKGLPEO_00972 5.9e-100
PGKGLPEO_00973 2e-106
PGKGLPEO_00974 1.1e-116 yeeN K transcriptional regulatory protein
PGKGLPEO_00975 2e-191 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
PGKGLPEO_00976 1.4e-242 MA20_26760 1.3.8.7 I COG1960 Acyl-CoA dehydrogenases
PGKGLPEO_00977 2.2e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_00978 2.5e-297 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGKGLPEO_00979 6.7e-96 K Transcriptional regulator
PGKGLPEO_00981 5.6e-68 S Thioesterase-like superfamily
PGKGLPEO_00982 3.9e-198 S Phosphotransferase enzyme family
PGKGLPEO_00983 8.8e-270 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGKGLPEO_00984 8.4e-100 glnH ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGKGLPEO_00985 9.9e-83 yecS_2 E COG0765 ABC-type amino acid transport system, permease component
PGKGLPEO_00986 9.5e-111 artM_2 3.6.3.21 E ABC transporter
PGKGLPEO_00987 6.8e-230 yobO M Pectate lyase superfamily protein
PGKGLPEO_00988 3.7e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
PGKGLPEO_00989 9.2e-141 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PGKGLPEO_00990 2.2e-126 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
PGKGLPEO_00991 8.2e-103 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
PGKGLPEO_00992 2e-94 ywhH S Aminoacyl-tRNA editing domain
PGKGLPEO_00993 1.7e-204 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PGKGLPEO_00994 2.2e-309 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGKGLPEO_00995 1.6e-188 2.7.7.65 T Diguanylate cyclase, GGDEF domain
PGKGLPEO_00997 1.3e-165 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PGKGLPEO_00998 1.5e-158 S Nuclease-related domain
PGKGLPEO_00999 8.4e-45
PGKGLPEO_01000 4.5e-26
PGKGLPEO_01001 6.7e-165 czcD P COG1230 Co Zn Cd efflux system component
PGKGLPEO_01002 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PGKGLPEO_01003 4.9e-114 M Glycosyltransferase like family 2
PGKGLPEO_01004 8.8e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
PGKGLPEO_01005 9.1e-173 mvaD 4.1.1.33 I GHMP kinases N terminal domain
PGKGLPEO_01006 2.9e-188 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
PGKGLPEO_01007 2.9e-111 yhfK GM NmrA-like family
PGKGLPEO_01008 6.4e-22
PGKGLPEO_01009 3.1e-93
PGKGLPEO_01011 8.7e-148 emrB P Major facilitator superfamily
PGKGLPEO_01012 8.8e-63 EGP Major facilitator Superfamily
PGKGLPEO_01013 1.4e-27 K Helix-turn-helix domain
PGKGLPEO_01014 4.7e-31
PGKGLPEO_01015 2.7e-31 S Domain of unknown function (DUF4177)
PGKGLPEO_01016 9.9e-307 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PGKGLPEO_01017 1.4e-153 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PGKGLPEO_01018 1.6e-282 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGKGLPEO_01019 8.9e-109 pncA Q COG1335 Amidases related to nicotinamidase
PGKGLPEO_01020 4.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PGKGLPEO_01021 0.0 ykoS
PGKGLPEO_01022 1.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PGKGLPEO_01023 2e-67 yngA S GtrA-like protein
PGKGLPEO_01024 6.6e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PGKGLPEO_01025 6.2e-74 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PGKGLPEO_01026 1.8e-181 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGKGLPEO_01027 8.5e-145 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PGKGLPEO_01028 8.6e-142 yycI S protein conserved in bacteria
PGKGLPEO_01029 1.7e-248 yycH S protein conserved in bacteria
PGKGLPEO_01030 0.0 vicK 2.7.13.3 T Histidine kinase
PGKGLPEO_01031 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGKGLPEO_01034 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PGKGLPEO_01035 3.7e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PGKGLPEO_01036 1.2e-71 rplI J binds to the 23S rRNA
PGKGLPEO_01037 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PGKGLPEO_01038 1.1e-146 yybS S membrane
PGKGLPEO_01039 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PGKGLPEO_01040 1.5e-86 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PGKGLPEO_01041 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PGKGLPEO_01042 7.4e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PGKGLPEO_01043 1.8e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PGKGLPEO_01044 2.6e-115 ribE 2.5.1.9 H Riboflavin synthase
PGKGLPEO_01045 2e-208 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PGKGLPEO_01046 5.9e-205 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PGKGLPEO_01047 4.2e-32 yyzM S protein conserved in bacteria
PGKGLPEO_01048 9.7e-161 ykuT M Mechanosensitive ion channel
PGKGLPEO_01049 3.3e-112 yyaC S Sporulation protein YyaC
PGKGLPEO_01050 6.2e-118 ydfK S Protein of unknown function (DUF554)
PGKGLPEO_01051 1.2e-149 spo0J K Belongs to the ParB family
PGKGLPEO_01052 6.9e-136 soj D COG1192 ATPases involved in chromosome partitioning
PGKGLPEO_01053 5.9e-152 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PGKGLPEO_01054 1.8e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PGKGLPEO_01055 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PGKGLPEO_01056 5.8e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PGKGLPEO_01057 8.2e-111 jag S single-stranded nucleic acid binding R3H
PGKGLPEO_01058 1.4e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGKGLPEO_01059 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PGKGLPEO_01060 2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGKGLPEO_01061 4.5e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PGKGLPEO_01062 2.4e-33 yaaA S S4 domain
PGKGLPEO_01063 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PGKGLPEO_01064 7.3e-11 yaaB S Domain of unknown function (DUF370)
PGKGLPEO_01065 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGKGLPEO_01066 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGKGLPEO_01067 6.8e-198 M1-161 T HD domain
PGKGLPEO_01068 1.1e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PGKGLPEO_01069 1.5e-121 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PGKGLPEO_01070 4e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
PGKGLPEO_01071 3.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PGKGLPEO_01073 0.0 clpC O Belongs to the ClpA ClpB family
PGKGLPEO_01074 7.8e-194 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PGKGLPEO_01075 6.1e-102 mcsA 2.7.14.1 S protein with conserved CXXC pairs
PGKGLPEO_01076 5.4e-75 ctsR K Belongs to the CtsR family
PGKGLPEO_01078 5.3e-44 S Protein of unknown function (DUF3969)
PGKGLPEO_01079 2.8e-246 L Transposase
PGKGLPEO_01080 1.3e-13
PGKGLPEO_01081 1.5e-75 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PGKGLPEO_01083 2.2e-117 ywbG M effector of murein hydrolase
PGKGLPEO_01084 3.7e-58 ywbH S LrgA family
PGKGLPEO_01085 2.3e-181 ywbI K Transcriptional regulator
PGKGLPEO_01086 0.0 asnO 6.3.5.4 E Asparagine synthase
PGKGLPEO_01087 1.4e-12 2.3.1.128 K Acetyltransferase (GNAT) domain
PGKGLPEO_01088 2.4e-53 2.3.1.128 K Acetyltransferase (GNAT) domain
PGKGLPEO_01089 3.9e-09 sidE D nuclear chromosome segregation
PGKGLPEO_01090 5.7e-36 ykuS S Belongs to the UPF0180 family
PGKGLPEO_01091 2.1e-25
PGKGLPEO_01092 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
PGKGLPEO_01093 6.7e-93 ywrA P COG2059 Chromate transport protein ChrA
PGKGLPEO_01094 1.8e-102 chrA P COG2059 Chromate transport protein ChrA
PGKGLPEO_01095 1.5e-83 ywrC K Transcriptional regulator
PGKGLPEO_01096 1.9e-10 EGP Uncharacterised MFS-type transporter YbfB
PGKGLPEO_01097 5.7e-79 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PGKGLPEO_01098 1.6e-227 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
PGKGLPEO_01099 4.1e-23 EGP Major facilitator Superfamily
PGKGLPEO_01100 2.5e-122 EGP Major facilitator Superfamily
PGKGLPEO_01102 3.8e-162 pocR K Sensory domain found in PocR
PGKGLPEO_01103 7.2e-228 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PGKGLPEO_01104 3.2e-211 yxjG 2.1.1.14 E Methionine synthase
PGKGLPEO_01105 1.1e-172 ydhF S Oxidoreductase
PGKGLPEO_01106 2.4e-24
PGKGLPEO_01107 4.1e-178 K cell envelope-related transcriptional attenuator
PGKGLPEO_01108 0.0 3.2.1.78 GH26 O cellulase activity
PGKGLPEO_01109 5.4e-09 3.2.1.78 GH26 O cellulase activity
PGKGLPEO_01110 0.0 ybeC E amino acid
PGKGLPEO_01111 6.5e-136 tnp L PFAM Transposase, Mutator
PGKGLPEO_01112 2.5e-272 L RNA-directed DNA polymerase (reverse transcriptase)
PGKGLPEO_01113 4.4e-146 hel M 5'-nucleotidase, lipoprotein e(P4)
PGKGLPEO_01116 1.8e-212 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
PGKGLPEO_01117 2.7e-34 K ArsR family transcriptional regulator
PGKGLPEO_01118 6.5e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PGKGLPEO_01119 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PGKGLPEO_01120 4.4e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PGKGLPEO_01121 1.9e-200 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
PGKGLPEO_01122 1.4e-181 K Transcriptional regulator
PGKGLPEO_01123 5.1e-32 S Cold-inducible protein YdjO
PGKGLPEO_01124 1.5e-14
PGKGLPEO_01126 8e-165 cvfB S protein conserved in bacteria
PGKGLPEO_01127 4e-71 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGKGLPEO_01128 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
PGKGLPEO_01129 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PGKGLPEO_01130 3.5e-07 yusP P Major facilitator superfamily
PGKGLPEO_01131 1.2e-274 yusP P Major facilitator superfamily
PGKGLPEO_01132 3.7e-210 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PGKGLPEO_01133 7.5e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PGKGLPEO_01134 1.5e-124 gntR1 K transcriptional
PGKGLPEO_01135 1.8e-181 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PGKGLPEO_01136 8.8e-228 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PGKGLPEO_01137 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
PGKGLPEO_01139 2.7e-167 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PGKGLPEO_01140 1.4e-113 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
PGKGLPEO_01141 1.5e-203 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PGKGLPEO_01142 2.4e-124 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGKGLPEO_01143 2.4e-259 yfnA E amino acid
PGKGLPEO_01144 1.2e-154 degV S protein conserved in bacteria
PGKGLPEO_01145 1.7e-257 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PGKGLPEO_01146 4.9e-128 comFC S Phosphoribosyl transferase domain
PGKGLPEO_01147 1.3e-69 yvyF S flagellar protein
PGKGLPEO_01148 3e-38 flgM KNU Negative regulator of flagellin synthesis
PGKGLPEO_01149 8.7e-73 flgN NOU FlgN protein
PGKGLPEO_01150 8.2e-288 flgK N flagellar hook-associated protein
PGKGLPEO_01151 6.3e-157 flgL N Belongs to the bacterial flagellin family
PGKGLPEO_01152 1.7e-79 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PGKGLPEO_01153 1.6e-33 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PGKGLPEO_01154 1.5e-21 S Nucleotidyltransferase domain
PGKGLPEO_01155 3.7e-99 secA U SEC-C motif
PGKGLPEO_01156 1.2e-62 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PGKGLPEO_01157 3.9e-09 S double-stranded DNA endodeoxyribonuclease activity
PGKGLPEO_01158 1.3e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PGKGLPEO_01160 2.9e-126 EGP Sugar (and other) transporter
PGKGLPEO_01162 6.7e-169 E COG1113 Gamma-aminobutyrate permease and related permeases
PGKGLPEO_01164 0.0 ycbZ 3.4.21.53 O AAA domain
PGKGLPEO_01166 2.9e-105 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PGKGLPEO_01168 5.1e-60 flaG N flagellar protein FlaG
PGKGLPEO_01169 3.4e-225 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PGKGLPEO_01170 8.6e-69 fliS N flagellar protein FliS
PGKGLPEO_01171 1.1e-56 fliT S bacterial-type flagellum organization
PGKGLPEO_01172 4.2e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PGKGLPEO_01173 4.3e-306 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PGKGLPEO_01174 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PGKGLPEO_01175 3.2e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PGKGLPEO_01176 6.1e-157 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
PGKGLPEO_01177 2.9e-51 cccB C COG2010 Cytochrome c, mono- and diheme variants
PGKGLPEO_01179 6.3e-137 ftsE D cell division ATP-binding protein FtsE
PGKGLPEO_01180 1.4e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PGKGLPEO_01181 2.6e-93 D peptidase
PGKGLPEO_01182 3.9e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGKGLPEO_01183 4.3e-247 metY 2.5.1.49 E O-acetylhomoserine
PGKGLPEO_01184 9.1e-181 1.1.1.3 E homoserine dehydrogenase
PGKGLPEO_01185 7.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
PGKGLPEO_01186 4.4e-222 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGKGLPEO_01187 1.2e-166 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGKGLPEO_01188 1e-160 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGKGLPEO_01189 5.6e-138 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
PGKGLPEO_01190 2e-177 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
PGKGLPEO_01191 2.1e-41 fdxA C 4Fe-4S binding domain
PGKGLPEO_01192 4.5e-46 S Family of unknown function (DUF5316)
PGKGLPEO_01193 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGKGLPEO_01194 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
PGKGLPEO_01195 5.3e-259 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PGKGLPEO_01196 3.9e-159 pstS P Phosphate
PGKGLPEO_01197 1.9e-159 pstC P probably responsible for the translocation of the substrate across the membrane
PGKGLPEO_01198 8.2e-157 pstA P Phosphate transport system permease
PGKGLPEO_01199 8e-154 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGKGLPEO_01200 8.9e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGKGLPEO_01201 6.7e-173 M Glycosyltransferase like family 2
PGKGLPEO_01202 0.0
PGKGLPEO_01203 5e-57 P EamA-like transporter family
PGKGLPEO_01204 1.5e-50 S EamA-like transporter family
PGKGLPEO_01205 1.4e-118 yfbR S HD containing hydrolase-like enzyme
PGKGLPEO_01206 2.4e-34 csbA S protein conserved in bacteria
PGKGLPEO_01207 1.4e-10 S Uncharacterized conserved protein (DUF2164)
PGKGLPEO_01208 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PGKGLPEO_01209 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PGKGLPEO_01210 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
PGKGLPEO_01211 6.1e-232 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PGKGLPEO_01212 1e-231 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PGKGLPEO_01213 4.5e-146 tagG GM Transport permease protein
PGKGLPEO_01214 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PGKGLPEO_01215 1.1e-169 yvlB S Putative adhesin
PGKGLPEO_01216 1.4e-32 yvlD S Membrane
PGKGLPEO_01217 2.7e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PGKGLPEO_01218 4.6e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PGKGLPEO_01219 2.9e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PGKGLPEO_01220 1.5e-73 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
PGKGLPEO_01221 3e-268 S COG0457 FOG TPR repeat
PGKGLPEO_01222 1.2e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PGKGLPEO_01223 3e-86 yvcI 3.6.1.55 F Nudix hydrolase
PGKGLPEO_01224 1.2e-168 rapZ S Displays ATPase and GTPase activities
PGKGLPEO_01225 1e-179 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PGKGLPEO_01226 4e-173 whiA K May be required for sporulation
PGKGLPEO_01227 4.3e-40 crh G Phosphocarrier protein Chr
PGKGLPEO_01228 2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PGKGLPEO_01230 1.4e-171 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
PGKGLPEO_01231 7.6e-134 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PGKGLPEO_01232 8.8e-59 ytzH S YtzH-like protein
PGKGLPEO_01233 6.2e-156 ytmP 2.7.1.89 M Phosphotransferase
PGKGLPEO_01234 7.5e-148 ytlQ
PGKGLPEO_01235 6.6e-107 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PGKGLPEO_01237 1.5e-158 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PGKGLPEO_01238 3.5e-274 pepV 3.5.1.18 E Dipeptidase
PGKGLPEO_01239 1.2e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
PGKGLPEO_01240 7e-287 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGKGLPEO_01241 4.1e-26 yteV S Sporulation protein Cse60
PGKGLPEO_01242 1.7e-10
PGKGLPEO_01244 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGKGLPEO_01245 1.5e-185 yttB EGP Major facilitator Superfamily
PGKGLPEO_01246 1.6e-42 ytzC S Protein of unknown function (DUF2524)
PGKGLPEO_01247 5.2e-104 ytqB J Putative rRNA methylase
PGKGLPEO_01249 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
PGKGLPEO_01250 2e-154 ytpA 3.1.1.5 I Alpha beta hydrolase
PGKGLPEO_01251 2.5e-73 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PGKGLPEO_01252 0.0 asnB 6.3.5.4 E Asparagine synthase
PGKGLPEO_01253 5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PGKGLPEO_01254 4.4e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PGKGLPEO_01255 4.8e-69 3.6.1.13, 3.6.1.55 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
PGKGLPEO_01256 1.9e-208 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PGKGLPEO_01257 1.5e-100 ywqN S NAD(P)H-dependent
PGKGLPEO_01258 1.4e-56 gntK 2.7.1.12, 2.7.1.17 G FGGY family of carbohydrate kinases, N-terminal domain
PGKGLPEO_01259 3.3e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PGKGLPEO_01260 8.8e-139 ytlC P ABC transporter
PGKGLPEO_01261 4.7e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PGKGLPEO_01262 6.5e-81 ytkD 3.6.1.55 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PGKGLPEO_01263 7.4e-39
PGKGLPEO_01264 5.6e-77 dps P Belongs to the Dps family
PGKGLPEO_01265 1.3e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PGKGLPEO_01267 3.8e-162 adcA P Belongs to the bacterial solute-binding protein 9 family
PGKGLPEO_01268 1.6e-23 S Domain of Unknown Function (DUF1540)
PGKGLPEO_01269 4.7e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PGKGLPEO_01270 1.9e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PGKGLPEO_01271 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PGKGLPEO_01272 1.5e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PGKGLPEO_01273 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PGKGLPEO_01274 1.8e-259 menF 5.4.4.2 HQ Isochorismate synthase
PGKGLPEO_01275 1.7e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
PGKGLPEO_01276 5.8e-85 S SMI1-KNR4 cell-wall
PGKGLPEO_01278 1e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PGKGLPEO_01279 2.3e-168 P ABC transporter substrate-binding protein
PGKGLPEO_01280 1.4e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
PGKGLPEO_01281 8.4e-134 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PGKGLPEO_01282 5.1e-139 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
PGKGLPEO_01283 1.4e-95 ssuE 1.5.1.38 S FMN reductase
PGKGLPEO_01284 6.4e-24 S Uncharacterized small protein (DUF2292)
PGKGLPEO_01285 1.8e-305 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PGKGLPEO_01286 3.9e-146 XK27_04815 S Membrane transport protein
PGKGLPEO_01288 1.5e-30 S Domain of unknown function (DUF202)
PGKGLPEO_01289 1.8e-103 P Integral membrane protein TerC family
PGKGLPEO_01290 2.4e-102 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PGKGLPEO_01291 9.4e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
PGKGLPEO_01292 1.2e-52 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
PGKGLPEO_01293 2.5e-78
PGKGLPEO_01294 2.2e-249 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGKGLPEO_01295 1.8e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PGKGLPEO_01296 0.0 2.7.1.202 K transcriptional regulator, MtlR
PGKGLPEO_01297 1.5e-155 kdsA 2.5.1.55 M Belongs to the KdsA family
PGKGLPEO_01298 1.8e-176 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
PGKGLPEO_01299 4.6e-163 V ATPases associated with a variety of cellular activities
PGKGLPEO_01300 2.2e-08
PGKGLPEO_01301 2.6e-230 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PGKGLPEO_01302 1.9e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PGKGLPEO_01303 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
PGKGLPEO_01304 9.4e-147 G Binding-protein-dependent transport system inner membrane component
PGKGLPEO_01305 1.1e-217 sugA G Binding-protein-dependent transport system inner membrane component
PGKGLPEO_01306 8.7e-229 G Bacterial extracellular solute-binding protein
PGKGLPEO_01307 4.1e-133 K helix_turn_helix, arabinose operon control protein
PGKGLPEO_01308 1e-136 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PGKGLPEO_01309 9.2e-52 S Iron-sulphur cluster biosynthesis
PGKGLPEO_01310 1.4e-176 yhfP 1.1.1.1 C Quinone oxidoreductase
PGKGLPEO_01311 1.3e-162 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PGKGLPEO_01312 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PGKGLPEO_01313 1.1e-73 3.4.21.121 O Belongs to the peptidase S8 family
PGKGLPEO_01314 1e-84
PGKGLPEO_01315 2.7e-146 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PGKGLPEO_01317 8.5e-131 IQ Short-chain dehydrogenase reductase sdr
PGKGLPEO_01318 3e-28 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PGKGLPEO_01319 5.2e-110 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PGKGLPEO_01320 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PGKGLPEO_01321 4.6e-158 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PGKGLPEO_01322 4.4e-123 yhcW 5.4.2.6 S hydrolase
PGKGLPEO_01323 1e-165 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PGKGLPEO_01324 1.1e-130 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PGKGLPEO_01325 2e-129 macB V ABC transporter, ATP-binding protein
PGKGLPEO_01326 9.5e-153 V COG0577 ABC-type antimicrobial peptide transport system, permease component
PGKGLPEO_01327 2.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGKGLPEO_01328 3.8e-232 T PhoQ Sensor
PGKGLPEO_01329 1.3e-21
PGKGLPEO_01330 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PGKGLPEO_01332 4.2e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PGKGLPEO_01333 2e-73 yabE S 3D domain
PGKGLPEO_01334 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PGKGLPEO_01335 6.1e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
PGKGLPEO_01336 5.9e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PGKGLPEO_01337 8.8e-167 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PGKGLPEO_01338 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PGKGLPEO_01339 3.5e-140 stp 3.1.3.16 T phosphatase
PGKGLPEO_01340 3.8e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PGKGLPEO_01341 5.3e-178 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGKGLPEO_01342 1.3e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PGKGLPEO_01343 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PGKGLPEO_01344 4.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGKGLPEO_01345 3.4e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PGKGLPEO_01346 1.3e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PGKGLPEO_01347 7.7e-46 ylzA S Belongs to the UPF0296 family
PGKGLPEO_01348 4.5e-155 yicC S stress-induced protein
PGKGLPEO_01349 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
PGKGLPEO_01350 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PGKGLPEO_01351 4.5e-164 yocS S -transporter
PGKGLPEO_01352 8.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PGKGLPEO_01353 3.1e-89 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
PGKGLPEO_01354 1.8e-79 L DDE superfamily endonuclease
PGKGLPEO_01355 2.4e-264 yihP G MFS/sugar transport protein
PGKGLPEO_01357 2.4e-113 sigH K Belongs to the sigma-70 factor family
PGKGLPEO_01358 8.7e-90 yacP S RNA-binding protein containing a PIN domain
PGKGLPEO_01359 1.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGKGLPEO_01360 4.4e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PGKGLPEO_01361 9.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGKGLPEO_01362 1.1e-108 cysE 2.3.1.30 E Serine acetyltransferase
PGKGLPEO_01363 7.2e-283 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGKGLPEO_01364 7.6e-09
PGKGLPEO_01365 3.6e-129 V CAAX protease self-immunity
PGKGLPEO_01366 1.3e-132 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PGKGLPEO_01367 1.1e-74 yycN 2.3.1.128, 2.3.1.57 K FR47-like protein
PGKGLPEO_01368 1.6e-233 lmrP E Transmembrane secretion effector
PGKGLPEO_01369 1.4e-74 E lactoylglutathione lyase activity
PGKGLPEO_01370 0.0 yjcD 3.6.4.12 L DNA helicase
PGKGLPEO_01371 1.4e-226 ywdJ F Xanthine uracil
PGKGLPEO_01372 6.1e-166 ytnM S membrane transporter protein
PGKGLPEO_01373 2.9e-238 E COG1113 Gamma-aminobutyrate permease and related permeases
PGKGLPEO_01374 8.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
PGKGLPEO_01375 4.6e-175 pfoS S Phosphotransferase system, EIIC
PGKGLPEO_01376 8.5e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PGKGLPEO_01377 1e-96 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
PGKGLPEO_01378 2.2e-96 yvbF K Belongs to the GbsR family
PGKGLPEO_01379 1.8e-209 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PGKGLPEO_01380 3.4e-115 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PGKGLPEO_01381 3.3e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PGKGLPEO_01382 1.2e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PGKGLPEO_01384 0.0 bga2 3.2.1.23 G beta-galactosidase
PGKGLPEO_01386 1.3e-174 K Transcriptional regulator
PGKGLPEO_01387 5.1e-210 EGP Major facilitator Superfamily
PGKGLPEO_01388 5.5e-74 K transcriptional
PGKGLPEO_01389 6.1e-131 ubiE Q Methyltransferase type 11
PGKGLPEO_01390 3.6e-210 M Glycosyl hydrolases family 25
PGKGLPEO_01391 1.2e-166 yfhF S nucleoside-diphosphate sugar epimerase
PGKGLPEO_01392 1.8e-158 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PGKGLPEO_01393 1.1e-84 thiW S Thiamine-precursor transporter protein (ThiW)
PGKGLPEO_01394 1.8e-13 yjhE S Phage tail protein
PGKGLPEO_01395 7.2e-192 yraQ S Predicted permease
PGKGLPEO_01396 6.5e-136 T Calcineurin-like phosphoesterase superfamily domain
PGKGLPEO_01397 3.1e-195 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
PGKGLPEO_01398 4.2e-200 selU S tRNA 2-selenouridine synthase
PGKGLPEO_01400 9.4e-261 dld 1.1.1.303, 1.1.1.4, 1.1.2.4 C Glycolate oxidase subunit
PGKGLPEO_01401 5.2e-156 IQ Enoyl-(Acyl carrier protein) reductase
PGKGLPEO_01402 7e-80 I N-terminal half of MaoC dehydratase
PGKGLPEO_01403 2.7e-70 I MaoC like domain
PGKGLPEO_01404 2.7e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PGKGLPEO_01405 2.4e-37 S Protein of unknown function (DUF1450)
PGKGLPEO_01406 6.5e-90 S Protein of unknown function (DUF1189)
PGKGLPEO_01407 6.9e-167 murB 1.3.1.98 M cell wall formation
PGKGLPEO_01408 3.1e-56
PGKGLPEO_01409 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
PGKGLPEO_01410 1.5e-169 yhcI S ABC-2 family transporter protein
PGKGLPEO_01411 8.6e-81 V VanZ like family
PGKGLPEO_01412 9.5e-77 dps P Ferritin-like domain
PGKGLPEO_01413 1.5e-228 mntH P H( )-stimulated, divalent metal cation uptake system
PGKGLPEO_01414 1.1e-118 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PGKGLPEO_01415 7.9e-96 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
PGKGLPEO_01416 3.9e-87 Q protein disulfide oxidoreductase activity
PGKGLPEO_01417 3e-22 S YpzG-like protein
PGKGLPEO_01419 6.3e-198 G Glycosyl hydrolases family 15
PGKGLPEO_01420 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PGKGLPEO_01421 7.1e-209 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PGKGLPEO_01422 3.1e-193 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
PGKGLPEO_01423 5.9e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
PGKGLPEO_01424 2.3e-156 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PGKGLPEO_01425 2e-148 xth 3.1.11.2 L exodeoxyribonuclease III
PGKGLPEO_01426 2.2e-78 sleB 3.5.1.28 M Cell wall
PGKGLPEO_01427 3.6e-216 fsr P COG0477 Permeases of the major facilitator superfamily
PGKGLPEO_01428 9.4e-130 IQ Enoyl-(Acyl carrier protein) reductase
PGKGLPEO_01429 2.3e-141 S Protein of unknown function (DUF2961)
PGKGLPEO_01430 1.1e-158 S Protein of unknown function
PGKGLPEO_01431 8.5e-142 IQ Enoyl-(Acyl carrier protein) reductase
PGKGLPEO_01432 5.2e-15 S Protein of unknown function (DUF2750)
PGKGLPEO_01433 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PGKGLPEO_01434 1.7e-78 ypmB S protein conserved in bacteria
PGKGLPEO_01435 1.7e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PGKGLPEO_01436 2.8e-254 asnS 6.1.1.22 J asparaginyl-tRNA
PGKGLPEO_01437 6.3e-243 L PFAM Transposase, IS4-like
PGKGLPEO_01438 0.0 htpG O Molecular chaperone. Has ATPase activity
PGKGLPEO_01439 1.8e-42 S Protein of unknown function, DUF600
PGKGLPEO_01440 2.7e-131 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PGKGLPEO_01441 6.1e-255 araP EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PGKGLPEO_01442 5.7e-104 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
PGKGLPEO_01443 1.4e-93 S Psort location CytoplasmicMembrane, score
PGKGLPEO_01444 1.1e-56 I Domain of unknown function (DUF4430)
PGKGLPEO_01445 4.6e-107 M FFAT motif binding
PGKGLPEO_01446 8.4e-46 S Protein of unknown function (DUF1048)
PGKGLPEO_01447 2.2e-52 S Protein of unknown function (DUF1048)
PGKGLPEO_01448 1.6e-39 S Protein of unknown function (DUF1048)
PGKGLPEO_01449 4.2e-59 K PadR family transcriptional regulator
PGKGLPEO_01450 4.4e-239 kgtP EGP -transporter
PGKGLPEO_01451 1.3e-292 mqo 1.1.5.4 S malate quinone oxidoreductase
PGKGLPEO_01452 3.4e-115 papP E amino acid ABC transporter
PGKGLPEO_01453 2.6e-102 E amino acid ABC transporter
PGKGLPEO_01454 5.8e-132 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
PGKGLPEO_01455 5.4e-142 cjaA ET Belongs to the bacterial solute-binding protein 3 family
PGKGLPEO_01456 3.5e-216 5.1.1.12 E Alanine racemase, N-terminal domain
PGKGLPEO_01457 1.6e-207 S Domain of unknown function (DUF1611_N) Rossmann-like domain
PGKGLPEO_01458 3.6e-226 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
PGKGLPEO_01459 2.6e-238 LYS1 1.5.1.7 E Saccharopine dehydrogenase
PGKGLPEO_01460 9.4e-106 glnQ2 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PGKGLPEO_01461 9.5e-35 artQ_1 E Binding-protein-dependent transport system inner membrane component
PGKGLPEO_01462 2.5e-41 artQ_1 E amino acid transport system, permease
PGKGLPEO_01463 6.9e-107 fliY ET Belongs to the bacterial solute-binding protein 3 family
PGKGLPEO_01464 4.4e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PGKGLPEO_01465 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
PGKGLPEO_01466 1.9e-135 gntR2 K UTRA
PGKGLPEO_01467 1.3e-41 T diguanylate cyclase activity
PGKGLPEO_01468 1.1e-302 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PGKGLPEO_01469 0.0 S MMPL domain protein
PGKGLPEO_01470 2.9e-98 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PGKGLPEO_01471 3.2e-113 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PGKGLPEO_01472 3.5e-300 msbA2 3.6.3.44 V ABC transporter
PGKGLPEO_01473 2.1e-126 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PGKGLPEO_01474 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PGKGLPEO_01475 2.1e-225 uraA F Xanthine uracil
PGKGLPEO_01476 2e-14 S Leucine-rich repeat (LRR) protein
PGKGLPEO_01477 2.9e-271 EGP Major facilitator Superfamily
PGKGLPEO_01480 3.7e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PGKGLPEO_01481 8.4e-153 M Glycosyl transferase family 8
PGKGLPEO_01482 3.1e-240 yisQ V Mate efflux family protein
PGKGLPEO_01483 1.8e-220 pilM NU Pilus assembly protein
PGKGLPEO_01484 4e-96
PGKGLPEO_01485 6.2e-140 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PGKGLPEO_01486 3.3e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PGKGLPEO_01487 2.9e-98 metI P COG2011 ABC-type metal ion transport system, permease component
PGKGLPEO_01488 2.1e-154 metQ M Belongs to the nlpA lipoprotein family
PGKGLPEO_01489 8.7e-240 cstA T Carbon starvation protein
PGKGLPEO_01490 5e-93 cstA T Carbon starvation protein
PGKGLPEO_01491 2.1e-207 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PGKGLPEO_01492 1.9e-130 thrE S Putative threonine/serine exporter
PGKGLPEO_01493 1.5e-74 S Threonine/Serine exporter, ThrE
PGKGLPEO_01494 2.8e-196 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PGKGLPEO_01495 1.6e-151 fhuC 3.6.3.34 HP ABC transporter
PGKGLPEO_01496 3.7e-171 fhuD P Periplasmic binding protein
PGKGLPEO_01497 3.7e-180 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGKGLPEO_01498 1.5e-181 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGKGLPEO_01499 2e-138 yfcA S membrane transporter protein
PGKGLPEO_01500 6.6e-54 ykkC P Multidrug resistance protein
PGKGLPEO_01501 1e-48 sugE P Multidrug resistance protein
PGKGLPEO_01502 3.1e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PGKGLPEO_01503 2.4e-58 Q Thioesterase superfamily
PGKGLPEO_01504 2.6e-43 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
PGKGLPEO_01505 4.4e-104 yetJ S Belongs to the BI1 family
PGKGLPEO_01506 4.6e-181 yxjG 2.1.1.14 E Methionine synthase
PGKGLPEO_01507 1.6e-219 yhjX P Major facilitator superfamily
PGKGLPEO_01508 1.5e-135 ypdB T LytTr DNA-binding domain
PGKGLPEO_01509 4.7e-311 ypdA 2.7.13.3 T Signal transduction histidine kinase
PGKGLPEO_01510 2e-94 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
PGKGLPEO_01511 3.9e-238 yhfA C membrane
PGKGLPEO_01512 2.8e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PGKGLPEO_01513 2.9e-221 ecsB U ABC transporter
PGKGLPEO_01514 1.9e-138 ecsA V transporter (ATP-binding protein)
PGKGLPEO_01515 1.4e-74 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PGKGLPEO_01516 1.1e-84 trpP S Tryptophan transporter TrpP
PGKGLPEO_01517 1.6e-18 yhaH S YtxH-like protein
PGKGLPEO_01518 6.7e-104 hpr K Negative regulator of protease production and sporulation
PGKGLPEO_01519 3.7e-54 yhaI S Protein of unknown function (DUF1878)
PGKGLPEO_01522 4.9e-154 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PGKGLPEO_01523 3e-27 yhaL S Sporulation protein YhaL
PGKGLPEO_01524 3.7e-179 yhaM L Shows a 3'-5' exoribonuclease activity
PGKGLPEO_01525 0.0 L AAA domain
PGKGLPEO_01526 2.8e-240 yhaO L DNA repair exonuclease
PGKGLPEO_01527 1e-164 ycgQ S membrane
PGKGLPEO_01528 1.6e-158 ycgR S permeases
PGKGLPEO_01529 1.8e-123 P Integral membrane protein TerC family
PGKGLPEO_01530 2.9e-27 S YhzD-like protein
PGKGLPEO_01531 5.2e-139 yhaR 5.3.3.18 I enoyl-CoA hydratase
PGKGLPEO_01532 3.2e-161 yhaX S hydrolases of the HAD superfamily
PGKGLPEO_01533 5.1e-54 yheA S Belongs to the UPF0342 family
PGKGLPEO_01534 5.9e-208 yheB S Belongs to the UPF0754 family
PGKGLPEO_01535 1.9e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
PGKGLPEO_01536 1.3e-212 yheC HJ YheC/D like ATP-grasp
PGKGLPEO_01537 5e-270 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
PGKGLPEO_01538 3.6e-224 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
PGKGLPEO_01539 6.1e-160 lrp QT PucR C-terminal helix-turn-helix domain
PGKGLPEO_01540 6.9e-206 msmK P Belongs to the ABC transporter superfamily
PGKGLPEO_01541 3.4e-29 sspB S spore protein
PGKGLPEO_01542 6e-263 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PGKGLPEO_01543 3.7e-137 K helix_turn_helix isocitrate lyase regulation
PGKGLPEO_01544 1.6e-120 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
PGKGLPEO_01545 9.2e-189 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
PGKGLPEO_01546 4.9e-268 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
PGKGLPEO_01547 1.1e-281 uxaA 4.2.1.7, 4.4.1.24 G Altronate
PGKGLPEO_01548 9.1e-275 uxaC 5.3.1.12 G glucuronate isomerase
PGKGLPEO_01549 1.1e-256 yjmB G MFS/sugar transport protein
PGKGLPEO_01550 6.1e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_01551 3.6e-162 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PGKGLPEO_01553 3e-215 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
PGKGLPEO_01554 0.0 pflB 2.3.1.54 C formate acetyltransferase
PGKGLPEO_01555 9.6e-143 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PGKGLPEO_01556 4.9e-99 1.5.1.38 S FMN reductase
PGKGLPEO_01557 1.2e-89
PGKGLPEO_01558 2.5e-170 bcrB S ABC transporter (permease)
PGKGLPEO_01559 1.1e-169 bcrA V ABC transporter, ATP-binding protein
PGKGLPEO_01560 6.8e-142 ypmR1 E G-D-S-L family
PGKGLPEO_01561 6.2e-32
PGKGLPEO_01563 5.8e-170 S High confidence in function and specificity
PGKGLPEO_01564 9.8e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGKGLPEO_01565 2.2e-249 ykoH3 T Histidine kinase
PGKGLPEO_01566 6e-109
PGKGLPEO_01567 1.7e-07
PGKGLPEO_01568 6.3e-30 ybxH S Family of unknown function (DUF5370)
PGKGLPEO_01569 1.9e-189 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PGKGLPEO_01570 8.7e-139 fecE 3.6.3.34 HP ABC transporter
PGKGLPEO_01571 1.2e-170 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGKGLPEO_01574 7.3e-169 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
PGKGLPEO_01576 1.9e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
PGKGLPEO_01577 1.4e-115 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PGKGLPEO_01578 1.2e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PGKGLPEO_01579 7.9e-222 ybbR S protein conserved in bacteria
PGKGLPEO_01580 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PGKGLPEO_01581 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PGKGLPEO_01583 2.5e-97 M1-431 S Protein of unknown function (DUF1706)
PGKGLPEO_01584 1.4e-144 3.1.2.21 I Acyl-ACP thioesterase
PGKGLPEO_01585 9.7e-86
PGKGLPEO_01586 3.8e-80 S cellulose binding
PGKGLPEO_01587 6.5e-213 G Major facilitator Superfamily
PGKGLPEO_01588 2.1e-126 EGP Major facilitator Superfamily
PGKGLPEO_01589 2.4e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PGKGLPEO_01590 1.5e-258 NT Chemoreceptor zinc-binding domain
PGKGLPEO_01591 8.3e-114 S Putative adhesin
PGKGLPEO_01592 3.9e-96 S Protein of unknown function (DUF1700)
PGKGLPEO_01593 1.3e-54 K PadR family transcriptional regulator
PGKGLPEO_01594 2e-183 NT chemotaxis protein
PGKGLPEO_01595 1.5e-248 EGP Major facilitator superfamily
PGKGLPEO_01596 1e-91 Q Isochorismatase family
PGKGLPEO_01597 2.6e-95 K Transcriptional regulator
PGKGLPEO_01598 3.1e-53
PGKGLPEO_01599 3.3e-125
PGKGLPEO_01600 1.1e-41 ltaA 4.1.2.48 E L-allo-threonine aldolase activity
PGKGLPEO_01601 1.4e-212 EGP Major Facilitator Superfamily
PGKGLPEO_01602 3.9e-170 F ATP-grasp domain
PGKGLPEO_01604 3.2e-211 K helix_turn_helix, Arsenical Resistance Operon Repressor
PGKGLPEO_01605 1.7e-51 ykvR S Protein of unknown function (DUF3219)
PGKGLPEO_01606 2.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGKGLPEO_01608 1.2e-217 yjbB G Major Facilitator Superfamily
PGKGLPEO_01610 3.4e-97 rimJ 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PGKGLPEO_01612 1e-87 2.3.1.128 J Acetyltransferase (GNAT) domain
PGKGLPEO_01613 1.3e-72 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
PGKGLPEO_01615 1.5e-190 yuxJ EGP Major facilitator Superfamily
PGKGLPEO_01616 9.4e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
PGKGLPEO_01617 5.3e-62 yuzC
PGKGLPEO_01619 5.3e-185 E Spore germination protein
PGKGLPEO_01620 4.3e-225 gerKC S spore germination
PGKGLPEO_01621 1.1e-279 gerKA EG Spore germination protein
PGKGLPEO_01623 1.9e-294 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PGKGLPEO_01624 6.4e-108 yuiC S protein conserved in bacteria
PGKGLPEO_01625 9.5e-47 yuiB S Putative membrane protein
PGKGLPEO_01626 2e-230 yumB 1.6.99.3 C NADH dehydrogenase
PGKGLPEO_01627 6.1e-185 yumC 1.18.1.2, 1.19.1.1 C reductase
PGKGLPEO_01628 3.1e-56 S response to antibiotic
PGKGLPEO_01629 5.3e-78 tcaA S response to antibiotic
PGKGLPEO_01630 9.6e-46 ycdA S Domain of unknown function (DUF4352)
PGKGLPEO_01631 8.1e-15 ycdA S Domain of unknown function (DUF4352)
PGKGLPEO_01632 2.2e-63 erpA S Belongs to the HesB IscA family
PGKGLPEO_01633 5.6e-61 yuzD S protein conserved in bacteria
PGKGLPEO_01634 5.1e-37 nifU O COG0694 Thioredoxin-like proteins and domains
PGKGLPEO_01635 1.8e-200 yutH S Spore coat protein
PGKGLPEO_01636 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
PGKGLPEO_01637 1.3e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PGKGLPEO_01638 1.9e-74 yutE S Protein of unknown function DUF86
PGKGLPEO_01639 3.4e-48 yutD S protein conserved in bacteria
PGKGLPEO_01640 2.5e-172 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PGKGLPEO_01641 3.2e-194 lytH M Peptidase, M23
PGKGLPEO_01642 1.3e-120 yunB S Sporulation protein YunB (Spo_YunB)
PGKGLPEO_01643 4e-47 yunC S Domain of unknown function (DUF1805)
PGKGLPEO_01644 3.3e-285 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PGKGLPEO_01645 2.9e-273 sufB O FeS cluster assembly
PGKGLPEO_01646 6.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
PGKGLPEO_01647 7e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGKGLPEO_01648 1.4e-242 sufD O assembly protein SufD
PGKGLPEO_01649 2.7e-143 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PGKGLPEO_01651 3.6e-51 traF CO Thioredoxin
PGKGLPEO_01652 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PGKGLPEO_01653 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
PGKGLPEO_01654 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
PGKGLPEO_01655 2.3e-215 fadA 2.3.1.16 I Belongs to the thiolase family
PGKGLPEO_01656 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
PGKGLPEO_01657 2.6e-14 S YuzL-like protein
PGKGLPEO_01658 7.4e-42
PGKGLPEO_01659 1.6e-55 yusN M Coat F domain
PGKGLPEO_01660 8.1e-205 rodA D Belongs to the SEDS family
PGKGLPEO_01661 1.9e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PGKGLPEO_01662 1.4e-283 cls2 I PLD-like domain
PGKGLPEO_01664 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PGKGLPEO_01665 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
PGKGLPEO_01666 7.3e-217 L PFAM Transposase, IS4-like
PGKGLPEO_01667 5.1e-89 E COG1177 ABC-type spermidine putrescine transport system, permease component II
PGKGLPEO_01668 4.8e-91 MA20_04255 P ABC-type spermidine putrescine transport system, permease component I
PGKGLPEO_01669 1.1e-120 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PGKGLPEO_01670 5.1e-137 MA20_04265 P Bacterial extracellular solute-binding protein
PGKGLPEO_01671 4.5e-197 hcnC 1.4.99.5 E FAD dependent oxidoreductase
PGKGLPEO_01672 7.9e-46 thcD 1.14.13.111, 1.18.1.3, 1.7.1.15 S BFD-like [2Fe-2S] binding domain
PGKGLPEO_01673 4.4e-82 C HI0933-like protein
PGKGLPEO_01674 9e-45 1.2.5.3, 1.3.99.16 C 2 iron, 2 sulfur cluster binding
PGKGLPEO_01675 6.9e-53 K UTRA domain
PGKGLPEO_01677 2.4e-83 2.3.1.57 K Acetyltransferase (GNAT) domain
PGKGLPEO_01678 2.2e-10
PGKGLPEO_01679 6.3e-224 S Psort location CytoplasmicMembrane, score
PGKGLPEO_01680 5.9e-120 yfiR K Transcriptional regulator
PGKGLPEO_01681 5.7e-144 yfiS EGP Major facilitator Superfamily
PGKGLPEO_01682 4.3e-55 yfiS EGP Major facilitator Superfamily
PGKGLPEO_01683 1e-134 thiX 2.7.1.50 P binding-protein-dependent transport systems inner membrane component
PGKGLPEO_01684 1.4e-184 nrtA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PGKGLPEO_01685 6e-75 S Glyoxalase bleomycin resistance protein dioxygenase
PGKGLPEO_01686 3.2e-144 yitD 4.4.1.19 S synthase
PGKGLPEO_01687 3.7e-128 comB 3.1.3.71 H Belongs to the ComB family
PGKGLPEO_01688 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PGKGLPEO_01689 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PGKGLPEO_01690 2.6e-160 aldY 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PGKGLPEO_01691 9.3e-104
PGKGLPEO_01692 1.1e-133 mta K transcriptional
PGKGLPEO_01693 4.5e-271 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
PGKGLPEO_01694 3e-176 yjlA EG Putative multidrug resistance efflux transporter
PGKGLPEO_01695 1.7e-187 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PGKGLPEO_01696 1.1e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PGKGLPEO_01697 1.8e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGKGLPEO_01698 2.1e-260 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PGKGLPEO_01699 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
PGKGLPEO_01700 6.5e-185 kefA M Mechanosensitive ion channel
PGKGLPEO_01701 1.5e-188 S COG0491 Zn-dependent hydrolases, including glyoxylases
PGKGLPEO_01702 9.1e-56 I SCP-2 sterol transfer family
PGKGLPEO_01704 2e-166 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
PGKGLPEO_01705 4e-104 S Appr-1'-p processing enzyme
PGKGLPEO_01706 4.4e-25 sspH S small acid-soluble spore protein
PGKGLPEO_01707 2.7e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PGKGLPEO_01708 2.3e-207 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
PGKGLPEO_01709 1.9e-283 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGKGLPEO_01710 1.9e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PGKGLPEO_01711 3.5e-193 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PGKGLPEO_01712 2.7e-145 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PGKGLPEO_01713 5.6e-156 pucR QT COG2508 Regulator of polyketide synthase expression
PGKGLPEO_01714 2.7e-151 pbuX F Permease family
PGKGLPEO_01715 2.9e-35 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 S OHCU decarboxylase
PGKGLPEO_01716 1e-204 P FAD-NAD(P)-binding
PGKGLPEO_01717 5e-36 uraH 3.5.2.17 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
PGKGLPEO_01718 7.6e-146 S Sucrose-6F-phosphate phosphohydrolase
PGKGLPEO_01719 8.4e-105 yozB S membrane
PGKGLPEO_01720 9e-60
PGKGLPEO_01721 1.9e-75 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PGKGLPEO_01722 7.7e-180 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
PGKGLPEO_01723 1.4e-117 kch P Ion channel
PGKGLPEO_01724 4.9e-10
PGKGLPEO_01726 1.4e-33 L COG3547 Transposase and inactivated derivatives
PGKGLPEO_01727 3.2e-37 T AMP binding
PGKGLPEO_01728 8e-54 MA20_14895 S Conserved hypothetical protein 698
PGKGLPEO_01729 6.9e-214 L Transposase
PGKGLPEO_01730 2.3e-112 araN G ABC transporter substrate-binding protein
PGKGLPEO_01731 2e-115 lacF G Binding-protein-dependent transport system inner membrane component
PGKGLPEO_01732 8.4e-103 araQ U Binding-protein-dependent transport system inner membrane component
PGKGLPEO_01733 7.3e-281 lacA 3.2.1.23 G beta-galactosidase
PGKGLPEO_01734 2e-83 K AraC-like ligand binding domain
PGKGLPEO_01735 5e-12 mrr V Mrr N-terminal domain
PGKGLPEO_01736 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PGKGLPEO_01737 8.1e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
PGKGLPEO_01738 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
PGKGLPEO_01739 1.5e-26
PGKGLPEO_01740 4.1e-113 E LysE type translocator
PGKGLPEO_01741 1.4e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PGKGLPEO_01742 2.9e-79 2.7.1.199 G COG2190 Phosphotransferase system IIA components
PGKGLPEO_01743 1.9e-155 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PGKGLPEO_01744 8.1e-276 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGKGLPEO_01745 2.9e-51 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGKGLPEO_01746 0.0 rafA 3.2.1.22 G Alpha-galactosidase
PGKGLPEO_01747 3.9e-105 proA_2 H Methyltransferase
PGKGLPEO_01748 1e-223 yhdR 2.6.1.1 E Aminotransferase
PGKGLPEO_01749 1.6e-111 yhbD K Protein of unknown function (DUF4004)
PGKGLPEO_01750 1.8e-53 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
PGKGLPEO_01751 4.5e-65 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
PGKGLPEO_01752 4.3e-245 yeeO V Mate efflux family protein
PGKGLPEO_01753 2.4e-156 mmgB 1.1.1.157 I Dehydrogenase
PGKGLPEO_01754 0.0 L AAA domain
PGKGLPEO_01755 3.8e-248 yhaO L Calcineurin-like phosphoesterase superfamily domain
PGKGLPEO_01756 3.6e-97 1.5.1.38 S FMN reductase
PGKGLPEO_01757 2.1e-154 S Aldo/keto reductase family
PGKGLPEO_01758 2.1e-137 I alpha/beta hydrolase fold
PGKGLPEO_01759 1.8e-113 M Spore coat protein
PGKGLPEO_01760 3.6e-182 tas 1.1.1.65 C Aldo/keto reductase family
PGKGLPEO_01761 9.9e-305 ubiE2 Q Methyltransferase domain
PGKGLPEO_01762 1.7e-70 ubiE2 Q Methyltransferase domain
PGKGLPEO_01763 1e-147 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
PGKGLPEO_01765 1.4e-147 ykrA S hydrolases of the HAD superfamily
PGKGLPEO_01766 5.1e-93 hxlB 4.1.2.43, 5.3.1.27 M arabinose-5-phosphate isomerase activity
PGKGLPEO_01767 1.4e-181 ykvZ 5.1.1.1 K Transcriptional regulator
PGKGLPEO_01768 5e-193 gutA G MFS/sugar transport protein
PGKGLPEO_01769 1.1e-200 gutB 1.1.1.14 E Dehydrogenase
PGKGLPEO_01770 1.3e-284 K NB-ARC domain
PGKGLPEO_01772 1.4e-228 yfkA S YfkB-like domain
PGKGLPEO_01773 3.3e-69
PGKGLPEO_01774 5.4e-27
PGKGLPEO_01775 2.1e-70 yxiE T Belongs to the universal stress protein A family
PGKGLPEO_01776 4.4e-29 K Helix-turn-helix XRE-family like proteins
PGKGLPEO_01778 9.2e-233 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
PGKGLPEO_01779 1.4e-26
PGKGLPEO_01780 5.4e-156 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PGKGLPEO_01781 1.4e-116 sapB S MgtC SapB transporter
PGKGLPEO_01782 9.9e-129 ccdA O cytochrome c biogenesis protein
PGKGLPEO_01783 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
PGKGLPEO_01784 4.6e-77 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
PGKGLPEO_01785 2.1e-76 yneK S Protein of unknown function (DUF2621)
PGKGLPEO_01786 3.9e-107 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PGKGLPEO_01787 8.6e-284 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
PGKGLPEO_01788 1.2e-174 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
PGKGLPEO_01790 2.3e-30 cspD K Cold shock
PGKGLPEO_01791 5e-78
PGKGLPEO_01792 3e-153 yjqC P Catalase
PGKGLPEO_01793 1.3e-76
PGKGLPEO_01795 8.1e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PGKGLPEO_01796 3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PGKGLPEO_01797 2.1e-140 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PGKGLPEO_01798 6.4e-221 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PGKGLPEO_01799 2.5e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PGKGLPEO_01800 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
PGKGLPEO_01801 3.1e-178 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PGKGLPEO_01802 4.8e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PGKGLPEO_01803 9.2e-264 argH 4.3.2.1 E argininosuccinate lyase
PGKGLPEO_01804 5.9e-227 dapL 2.6.1.83 E Aminotransferase
PGKGLPEO_01805 1.3e-47 feoA P COG1918 Fe2 transport system protein A
PGKGLPEO_01806 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PGKGLPEO_01807 1.1e-23 S Virus attachment protein p12 family
PGKGLPEO_01808 1.4e-109 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PGKGLPEO_01809 1.1e-50 tnrA K transcriptional
PGKGLPEO_01810 2.6e-128 yvpB NU protein conserved in bacteria
PGKGLPEO_01811 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGKGLPEO_01812 2e-230 nrnB S phosphohydrolase (DHH superfamily)
PGKGLPEO_01813 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
PGKGLPEO_01814 6.4e-73 yjlC S Protein of unknown function (DUF1641)
PGKGLPEO_01815 7.9e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PGKGLPEO_01816 1.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PGKGLPEO_01817 6e-222 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGKGLPEO_01818 0.0 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PGKGLPEO_01819 2.5e-155 glcT K antiterminator
PGKGLPEO_01820 4.7e-233 pbuG S permease
PGKGLPEO_01822 0.0 ywjA V ABC transporter
PGKGLPEO_01823 6.1e-211 ynfM EGP Major facilitator Superfamily
PGKGLPEO_01824 1.8e-116 yfiK K Regulator
PGKGLPEO_01825 5.4e-198 T Histidine kinase
PGKGLPEO_01826 1.2e-169 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
PGKGLPEO_01827 3.8e-199 yfiM V ABC-2 type transporter
PGKGLPEO_01828 3.7e-202 yfiN V COG0842 ABC-type multidrug transport system, permease component
PGKGLPEO_01830 1.5e-51 S PFAM Uncharacterised protein family UPF0236
PGKGLPEO_01832 6.4e-255 ybhI P Sodium:sulfate symporter transmembrane region
PGKGLPEO_01833 3.9e-88 endA 3.1.21.1 L Endonuclease I
PGKGLPEO_01834 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
PGKGLPEO_01836 1.5e-131
PGKGLPEO_01837 9.2e-127 yhcG V ABC transporter, ATP-binding protein
PGKGLPEO_01838 1.6e-58 yhcF K Transcriptional regulator
PGKGLPEO_01839 4.6e-97 padR K transcriptional
PGKGLPEO_01840 5.1e-95 padC Q Phenolic acid decarboxylase
PGKGLPEO_01841 7.4e-115 ywnB S NAD(P)H-binding
PGKGLPEO_01842 1.4e-72 ywnA K Transcriptional regulator
PGKGLPEO_01843 0.0 pepF2 E COG1164 Oligoendopeptidase F
PGKGLPEO_01844 4.3e-08 L Transposase domain (DUF772)
PGKGLPEO_01847 1.3e-196 L DDE superfamily endonuclease
PGKGLPEO_01848 2.8e-34 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PGKGLPEO_01849 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
PGKGLPEO_01850 2.1e-263 melB G MFS/sugar transport protein
PGKGLPEO_01851 4.7e-182 K helix_turn_helix, arabinose operon control protein
PGKGLPEO_01853 1.2e-216 araR K transcriptional
PGKGLPEO_01854 1.5e-197 chvE G ABC transporter
PGKGLPEO_01855 6.8e-284 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PGKGLPEO_01856 3.5e-181 gguB G Belongs to the binding-protein-dependent transport system permease family
PGKGLPEO_01857 1e-223 mvaS 2.3.3.10 I synthase
PGKGLPEO_01858 2.7e-182 yaaC S YaaC-like Protein
PGKGLPEO_01859 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PGKGLPEO_01860 8.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PGKGLPEO_01861 1.6e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PGKGLPEO_01862 4.4e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PGKGLPEO_01863 2.9e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PGKGLPEO_01864 2.9e-09
PGKGLPEO_01865 3.7e-125 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
PGKGLPEO_01866 5.4e-118 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
PGKGLPEO_01867 2.6e-252 yaaH M Glycoside Hydrolase Family
PGKGLPEO_01868 1e-87 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PGKGLPEO_01869 7e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGKGLPEO_01870 1.3e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PGKGLPEO_01871 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PGKGLPEO_01872 6.9e-09 S Protein of unknown function (DUF2508)
PGKGLPEO_01873 5.7e-37 bofA S Sigma-K factor-processing regulatory protein BofA
PGKGLPEO_01874 2.7e-171 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_01875 6.6e-242 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PGKGLPEO_01876 6.5e-193 yeeE S Sulphur transport
PGKGLPEO_01877 6.9e-36 yeeD O Belongs to the sulfur carrier protein TusA family
PGKGLPEO_01882 3e-09
PGKGLPEO_01883 3.4e-252 zraR KT Transcriptional regulator
PGKGLPEO_01884 7.8e-296 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGKGLPEO_01885 0.0 6.2.1.1 I AMP-dependent synthetase
PGKGLPEO_01886 3e-212 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
PGKGLPEO_01887 9.7e-250 yngH 6.3.4.14, 6.3.4.6, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
PGKGLPEO_01888 7.7e-13 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
PGKGLPEO_01889 4.3e-161 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
PGKGLPEO_01890 4.3e-133 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PGKGLPEO_01891 6.7e-292 yngE I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PGKGLPEO_01892 2.5e-77 K Acetyltransferase (GNAT) domain
PGKGLPEO_01895 7.2e-98 O HI0933-like protein
PGKGLPEO_01897 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGKGLPEO_01898 3.8e-162 ygxA S Nucleotidyltransferase-like
PGKGLPEO_01899 5e-57 ygzB S UPF0295 protein
PGKGLPEO_01900 1.3e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
PGKGLPEO_01901 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PGKGLPEO_01902 3.1e-164 alsR K LysR substrate binding domain
PGKGLPEO_01903 9.8e-82 perR P Belongs to the Fur family
PGKGLPEO_01904 5.2e-101 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
PGKGLPEO_01905 1.5e-65 P Ion transport
PGKGLPEO_01906 7.3e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PGKGLPEO_01907 9.2e-189 ssuA P ABC transporter substrate-binding protein
PGKGLPEO_01908 2.8e-140 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PGKGLPEO_01909 1.1e-144 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PGKGLPEO_01910 2.2e-111 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGKGLPEO_01911 8e-230 yitG EGP Major facilitator Superfamily
PGKGLPEO_01912 2.1e-29
PGKGLPEO_01913 1.5e-13
PGKGLPEO_01914 1.1e-38 yqhV S Protein of unknown function (DUF2619)
PGKGLPEO_01915 1.9e-187 ygaE S Membrane
PGKGLPEO_01916 2.4e-153 K transcriptional
PGKGLPEO_01917 1.4e-249 sacX 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PGKGLPEO_01918 7.2e-153 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PGKGLPEO_01919 2.9e-204 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
PGKGLPEO_01920 0.0 ygaD V ABC transporter
PGKGLPEO_01921 1.3e-104 ygaC J Belongs to the UPF0374 family
PGKGLPEO_01922 2.7e-36 ygaB S YgaB-like protein
PGKGLPEO_01923 3.3e-09 sspE S Small, acid-soluble spore protein, gamma-type
PGKGLPEO_01924 5.9e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_01925 2.2e-165 gltC K Transcriptional regulator
PGKGLPEO_01926 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
PGKGLPEO_01927 1.5e-288 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PGKGLPEO_01928 4.3e-52 S YfzA-like protein
PGKGLPEO_01929 3.2e-99 S ABC-2 family transporter protein
PGKGLPEO_01930 1.5e-158 V ABC transporter
PGKGLPEO_01931 3.1e-22 sspK S reproduction
PGKGLPEO_01932 1.7e-187 yfhP S membrane-bound metal-dependent
PGKGLPEO_01933 3.7e-215 mutY L A G-specific
PGKGLPEO_01934 9.8e-52 yfhH S Protein of unknown function (DUF1811)
PGKGLPEO_01935 8.1e-143 recX 2.4.1.337 GT4 S Modulates RecA activity
PGKGLPEO_01937 8.5e-24 yfhD S YfhD-like protein
PGKGLPEO_01938 7.6e-146 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PGKGLPEO_01939 3.2e-83 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PGKGLPEO_01940 6e-258 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
PGKGLPEO_01941 1.2e-183 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PGKGLPEO_01942 3.3e-109 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
PGKGLPEO_01943 1.6e-263 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PGKGLPEO_01944 6.8e-207 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
PGKGLPEO_01945 2.1e-120 V ATPases associated with a variety of cellular activities
PGKGLPEO_01946 2.2e-188 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PGKGLPEO_01948 1.1e-07
PGKGLPEO_01949 5.9e-86 S Stage II sporulation protein M
PGKGLPEO_01950 2e-126 V ABC transporter
PGKGLPEO_01952 1.4e-43 S Bacteriocin class IId cyclical uberolysin-like
PGKGLPEO_01954 0.0 XK27_10205
PGKGLPEO_01956 3.4e-61
PGKGLPEO_01957 7e-127 V AAA domain, putative AbiEii toxin, Type IV TA system
PGKGLPEO_01959 1.6e-112 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGKGLPEO_01960 0.0 comP 2.7.13.3 T Histidine kinase
PGKGLPEO_01961 4.3e-52 ywdH 1.2.1.3, 1.2.1.71 C Belongs to the aldehyde dehydrogenase family
PGKGLPEO_01962 3.4e-49 ywdH 1.2.1.3, 1.2.1.71 C Belongs to the aldehyde dehydrogenase family
PGKGLPEO_01963 1.3e-204 acrA1_1 Q Male sterility protein
PGKGLPEO_01964 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PGKGLPEO_01966 8.6e-239 mcpA NT chemotaxis protein
PGKGLPEO_01967 8e-182 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGKGLPEO_01968 1.1e-222 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PGKGLPEO_01969 1.1e-300 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGKGLPEO_01970 5.9e-183 S Phosphotransferase system, EIIC
PGKGLPEO_01971 1e-220 2.6.1.9 S HAD-hyrolase-like
PGKGLPEO_01972 9.3e-192 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PGKGLPEO_01973 1.6e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGKGLPEO_01974 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGKGLPEO_01975 5.9e-205 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PGKGLPEO_01976 6.6e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PGKGLPEO_01977 3.6e-196 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PGKGLPEO_01978 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
PGKGLPEO_01979 0.0 ilvB 2.2.1.6 E Acetolactate synthase
PGKGLPEO_01980 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PGKGLPEO_01981 3.9e-243 braB E Component of the transport system for branched-chain amino acids
PGKGLPEO_01982 3.7e-154 T STAS domain
PGKGLPEO_01983 2.1e-246
PGKGLPEO_01984 8.9e-33 L COG2963 Transposase and inactivated derivatives
PGKGLPEO_01985 3.3e-58 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
PGKGLPEO_01986 1.6e-63 arsD S Arsenical resistance operon trans-acting repressor ArsD
PGKGLPEO_01987 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
PGKGLPEO_01988 1.2e-97 padR K Domain of unknown function (DUF2703)
PGKGLPEO_01989 8e-191 arsB P Arsenic resistance protein
PGKGLPEO_01990 2.4e-71 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
PGKGLPEO_01992 3.5e-185 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGKGLPEO_01993 1.1e-77
PGKGLPEO_01994 2.9e-54 S DsrE/DsrF-like family
PGKGLPEO_01995 7.4e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
PGKGLPEO_01996 4.6e-187 EGP Major facilitator Superfamily
PGKGLPEO_01997 1e-46 K transcriptional
PGKGLPEO_01999 1.1e-78 K FCD
PGKGLPEO_02000 1.1e-124 garR 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PGKGLPEO_02001 1.2e-205 S Putative nucleotide-binding of sugar-metabolising enzyme
PGKGLPEO_02002 6.7e-155 gntT EG COG2610 H gluconate symporter and related permeases
PGKGLPEO_02003 6.6e-10
PGKGLPEO_02004 7.9e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PGKGLPEO_02005 1.6e-160 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PGKGLPEO_02006 1.9e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PGKGLPEO_02007 1.5e-180 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PGKGLPEO_02008 3.2e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PGKGLPEO_02009 8.3e-221 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
PGKGLPEO_02010 3.3e-132 bshB1 S proteins, LmbE homologs
PGKGLPEO_02011 1.5e-149 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PGKGLPEO_02012 4.4e-58 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
PGKGLPEO_02013 6.3e-60 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
PGKGLPEO_02014 3.1e-81 queT S QueT transporter
PGKGLPEO_02015 2.4e-103 yugP S Zn-dependent protease
PGKGLPEO_02016 6e-143 ypjB S sporulation protein
PGKGLPEO_02017 4.3e-109 ypjA S membrane
PGKGLPEO_02018 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
PGKGLPEO_02019 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
PGKGLPEO_02020 1e-98 qcrA C Menaquinol-cytochrome c reductase
PGKGLPEO_02021 2e-85 ypiF S Protein of unknown function (DUF2487)
PGKGLPEO_02022 1.7e-99 ypiB S Belongs to the UPF0302 family
PGKGLPEO_02023 4.2e-239 S COG0457 FOG TPR repeat
PGKGLPEO_02024 2.3e-240 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PGKGLPEO_02025 1.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PGKGLPEO_02026 9.3e-211 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGKGLPEO_02027 2.9e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PGKGLPEO_02028 5.3e-206 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PGKGLPEO_02029 3.4e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PGKGLPEO_02030 3.2e-144 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
PGKGLPEO_02031 1.6e-76 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PGKGLPEO_02032 3.3e-175 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PGKGLPEO_02033 6.4e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PGKGLPEO_02034 7.8e-146 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PGKGLPEO_02035 2.8e-32 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PGKGLPEO_02036 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PGKGLPEO_02037 1.8e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PGKGLPEO_02038 1.2e-137 yphF
PGKGLPEO_02039 9.6e-08 yphE S Protein of unknown function (DUF2768)
PGKGLPEO_02040 4.3e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PGKGLPEO_02041 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PGKGLPEO_02042 7e-19 yphA
PGKGLPEO_02043 7.3e-14 S YpzI-like protein
PGKGLPEO_02044 1e-204 rpsA 1.17.7.4 J Ribosomal protein S1
PGKGLPEO_02045 6.4e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PGKGLPEO_02046 2.5e-118 ypfA M Flagellar protein YcgR
PGKGLPEO_02047 2.9e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
PGKGLPEO_02048 3.9e-150 sleB 3.5.1.28 M Spore cortex-lytic enzyme
PGKGLPEO_02049 2e-126 prsW S Involved in the degradation of specific anti-sigma factors
PGKGLPEO_02050 2.8e-190 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
PGKGLPEO_02051 1.2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PGKGLPEO_02052 2.7e-111 mecB NOT Negative regulator of genetic competence (MecA)
PGKGLPEO_02053 6.3e-145 ypbG S Calcineurin-like phosphoesterase superfamily domain
PGKGLPEO_02054 2.8e-32 cotJA S Spore coat associated protein JA (CotJA)
PGKGLPEO_02055 9.5e-45 cotJB S CotJB protein
PGKGLPEO_02056 2.3e-104 cotJC P Spore Coat
PGKGLPEO_02057 2e-79 ypbF S Protein of unknown function (DUF2663)
PGKGLPEO_02059 2.9e-102 ypbD S metal-dependent membrane protease
PGKGLPEO_02060 4.1e-286 recQ 3.6.4.12 L DNA helicase
PGKGLPEO_02061 8.1e-207 ypbB 5.1.3.1 S protein conserved in bacteria
PGKGLPEO_02062 4.7e-41 fer C Ferredoxin
PGKGLPEO_02063 4.3e-98 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PGKGLPEO_02064 1.4e-135 M COG0739 Membrane proteins related to metalloendopeptidases
PGKGLPEO_02065 0.0 resE 2.7.13.3 T Histidine kinase
PGKGLPEO_02066 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGKGLPEO_02067 2.8e-224 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PGKGLPEO_02068 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
PGKGLPEO_02069 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PGKGLPEO_02070 9.9e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PGKGLPEO_02071 6.4e-88 spmB S Spore maturation protein
PGKGLPEO_02072 5.2e-96 spmA S Spore maturation protein
PGKGLPEO_02073 1.9e-211 dacB 3.4.16.4 M Belongs to the peptidase S11 family
PGKGLPEO_02074 2.6e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PGKGLPEO_02075 9.4e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PGKGLPEO_02077 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGKGLPEO_02078 2.8e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PGKGLPEO_02079 1.9e-267 spoVAF EG Stage V sporulation protein AF
PGKGLPEO_02080 1.9e-106 spoVAEA S Stage V sporulation protein AE
PGKGLPEO_02081 1.3e-67 spoVAB S Stage V sporulation protein AB
PGKGLPEO_02082 2.8e-111 spoVAA S Stage V sporulation protein AA
PGKGLPEO_02083 1.1e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGKGLPEO_02084 1.1e-74 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PGKGLPEO_02085 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
PGKGLPEO_02086 3.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
PGKGLPEO_02087 2.7e-168 xerD L recombinase XerD
PGKGLPEO_02088 1.7e-34 S Protein of unknown function (DUF4227)
PGKGLPEO_02089 1.6e-85 fur P Belongs to the Fur family
PGKGLPEO_02090 1.1e-105 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PGKGLPEO_02091 1.9e-225 yqxK 3.6.4.12 L DNA helicase
PGKGLPEO_02092 1.6e-97 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
PGKGLPEO_02094 3e-162 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
PGKGLPEO_02097 9.4e-110 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PGKGLPEO_02098 4.8e-216 yaaN P Belongs to the TelA family
PGKGLPEO_02099 2.8e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
PGKGLPEO_02100 1.6e-242 yaaH_2 M Glycoside Hydrolase Family
PGKGLPEO_02101 2.7e-55 S YolD-like protein
PGKGLPEO_02102 2e-241 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGKGLPEO_02103 1.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
PGKGLPEO_02104 1.4e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGKGLPEO_02105 2.2e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PGKGLPEO_02106 4.2e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PGKGLPEO_02107 7.2e-228 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGKGLPEO_02108 2.6e-80 cheW NT COG0835 Chemotaxis signal transduction protein
PGKGLPEO_02109 1.7e-204 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
PGKGLPEO_02110 1.7e-95 yqjB S protein conserved in bacteria
PGKGLPEO_02111 9.3e-77 yqiW S Belongs to the UPF0403 family
PGKGLPEO_02112 6.7e-162 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
PGKGLPEO_02113 2.2e-203 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGKGLPEO_02114 8.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PGKGLPEO_02115 5.9e-188 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PGKGLPEO_02116 6.7e-262 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PGKGLPEO_02117 5.2e-209 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
PGKGLPEO_02118 4.8e-293 bkdR 2.7.13.3 KT Transcriptional regulator
PGKGLPEO_02119 4.4e-36 yqzF S Protein of unknown function (DUF2627)
PGKGLPEO_02120 5.1e-136 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PGKGLPEO_02121 8.1e-140 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PGKGLPEO_02122 1.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
PGKGLPEO_02123 1.8e-293 recN L May be involved in recombinational repair of damaged DNA
PGKGLPEO_02124 1.2e-79 argR K Regulates arginine biosynthesis genes
PGKGLPEO_02125 5.7e-144 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
PGKGLPEO_02126 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PGKGLPEO_02127 1.2e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PGKGLPEO_02128 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGKGLPEO_02129 8.4e-238 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGKGLPEO_02130 1.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PGKGLPEO_02131 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PGKGLPEO_02132 1.9e-68 yqhY S protein conserved in bacteria
PGKGLPEO_02133 8.1e-257 accC 6.3.4.14, 6.3.4.6, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PGKGLPEO_02134 5.2e-81 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PGKGLPEO_02135 5.5e-79 spoIIIAH S SpoIIIAH-like protein
PGKGLPEO_02136 2.5e-110 spoIIIAG S stage III sporulation protein AG
PGKGLPEO_02137 1.1e-107 spoIIIAF S stage III sporulation protein AF
PGKGLPEO_02138 2.6e-190 spoIIIAE S stage III sporulation protein AE
PGKGLPEO_02139 1.7e-58 spoIIIAD S Stage III sporulation protein AD
PGKGLPEO_02140 1.4e-27 spoIIIAC S stage III sporulation protein AC
PGKGLPEO_02141 9.8e-86 spoIIIAB S Stage III sporulation protein
PGKGLPEO_02142 2.1e-171 spoIIIAA S stage III sporulation protein AA
PGKGLPEO_02143 1.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PGKGLPEO_02144 4.6e-162 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PGKGLPEO_02145 5.1e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
PGKGLPEO_02146 7e-86 yqhR S Conserved membrane protein YqhR
PGKGLPEO_02147 2e-166 yqhQ S Protein of unknown function (DUF1385)
PGKGLPEO_02148 1.3e-10 yqhP
PGKGLPEO_02149 2e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
PGKGLPEO_02150 2.1e-166 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PGKGLPEO_02151 6.7e-175 paaX K PaaX-like protein
PGKGLPEO_02152 1.5e-217 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Belongs to the thiolase family
PGKGLPEO_02153 5.4e-153 ditN 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
PGKGLPEO_02154 8.5e-287 aldA 1.2.1.3, 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
PGKGLPEO_02155 2.9e-24 paaG 5.3.3.18 I Enoyl-CoA hydratase
PGKGLPEO_02156 3.7e-99 ycgT 1.18.1.2, 1.19.1.1 C reductase
PGKGLPEO_02158 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
PGKGLPEO_02159 1e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PGKGLPEO_02160 7.7e-67 yqhL P COG0607 Rhodanese-related sulfurtransferase
PGKGLPEO_02161 1.6e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PGKGLPEO_02162 1.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PGKGLPEO_02163 1.4e-214 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
PGKGLPEO_02164 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PGKGLPEO_02165 5.3e-155 yqhG S Bacterial protein YqhG of unknown function
PGKGLPEO_02166 6.7e-10 yqzE S YqzE-like protein
PGKGLPEO_02167 2.6e-100 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PGKGLPEO_02168 6e-61 S ComG operon protein 7
PGKGLPEO_02169 1.1e-83 comGF U COG4940 Competence protein ComGF
PGKGLPEO_02171 7.2e-77 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
PGKGLPEO_02172 4e-50 comGC U Required for transformation and DNA binding
PGKGLPEO_02173 4e-173 comGB NU COG1459 Type II secretory pathway, component PulF
PGKGLPEO_02174 2.8e-210 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PGKGLPEO_02175 5.2e-130 K Helix-turn-helix domain
PGKGLPEO_02176 5.7e-36 yqgY S Protein of unknown function (DUF2626)
PGKGLPEO_02177 1e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PGKGLPEO_02178 7.5e-22 yqgW S Protein of unknown function (DUF2759)
PGKGLPEO_02179 8.4e-179 glcK 2.7.1.2 G Glucokinase
PGKGLPEO_02180 4.5e-30 yqgQ S protein conserved in bacteria
PGKGLPEO_02181 1.3e-207 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PGKGLPEO_02183 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PGKGLPEO_02184 1.2e-53 yqzD
PGKGLPEO_02185 0.0 mrdA 3.4.16.4 M penicillin-binding protein
PGKGLPEO_02186 1.5e-217 yqgE EGP Major facilitator superfamily
PGKGLPEO_02187 1e-208 L PFAM Transposase, IS4-like
PGKGLPEO_02189 3.6e-55 S Heat induced stress protein YflT
PGKGLPEO_02190 2.2e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PGKGLPEO_02191 7.2e-37 S Family of unknown function (DUF5327)
PGKGLPEO_02192 1.3e-58 ywdK S small membrane protein
PGKGLPEO_02193 2.2e-81 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PGKGLPEO_02194 1.6e-145 ywfI C May function as heme-dependent peroxidase
PGKGLPEO_02195 1.8e-173 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
PGKGLPEO_02196 1.7e-151 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PGKGLPEO_02197 8e-70 K Transcriptional
PGKGLPEO_02198 1.8e-110 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
PGKGLPEO_02199 5.9e-220 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGKGLPEO_02200 1.6e-216 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PGKGLPEO_02201 9.4e-140 ypuA S Secreted protein
PGKGLPEO_02202 1.2e-96
PGKGLPEO_02203 3.4e-68 S response to pH
PGKGLPEO_02204 3.7e-108 che
PGKGLPEO_02205 4.1e-297 K helix_turn_helix, Lux Regulon
PGKGLPEO_02207 3.5e-249 S Protein of unknown function DUF262
PGKGLPEO_02208 0.0 S Protein of unknown function (DUF1524)
PGKGLPEO_02209 2e-74 EGP Major facilitator Superfamily
PGKGLPEO_02210 5.1e-254 ydjE EGP Major facilitator superfamily
PGKGLPEO_02211 4.8e-157 yxxF EG EamA-like transporter family
PGKGLPEO_02212 3.4e-208 adhC 1.1.1.1 C Zinc-binding dehydrogenase
PGKGLPEO_02214 2.6e-191 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGKGLPEO_02215 2e-29 yetF3 K membrane
PGKGLPEO_02216 9.4e-23 yetF3 K membrane
PGKGLPEO_02219 1.6e-08
PGKGLPEO_02223 4.5e-39 spoVIF S Stage VI sporulation protein F
PGKGLPEO_02225 3.8e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGKGLPEO_02226 1.5e-94 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
PGKGLPEO_02227 1.8e-141 yjcH P COG2382 Enterochelin esterase and related enzymes
PGKGLPEO_02229 8.5e-25 L Transposase, IS4 family protein
PGKGLPEO_02230 1.7e-58 K MarR family
PGKGLPEO_02231 7.9e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PGKGLPEO_02232 1.3e-231 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PGKGLPEO_02233 3.2e-110 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGKGLPEO_02234 1.5e-37 gcvR T Belongs to the UPF0237 family
PGKGLPEO_02235 1.4e-248 XK27_08635 S UPF0210 protein
PGKGLPEO_02236 9.2e-192 ptxS K transcriptional
PGKGLPEO_02238 3.6e-156 S Protein of unknown function (DUF1646)
PGKGLPEO_02239 2e-42 K Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PGKGLPEO_02240 1.2e-266 K PTS system fructose IIA component
PGKGLPEO_02241 3.2e-107 K PFAM sigma-54 factor interaction domain-containing protein
PGKGLPEO_02242 1.7e-70 2.7.1.191 G PTS system fructose IIA component
PGKGLPEO_02243 9.7e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
PGKGLPEO_02244 1e-129 G PTS system sorbose-specific iic component
PGKGLPEO_02245 4.8e-48 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
PGKGLPEO_02246 2e-43 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
PGKGLPEO_02247 1e-163 EG Gluconate proton symporter
PGKGLPEO_02248 6.2e-191 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PGKGLPEO_02249 1.7e-73 KT Sugar diacid utilization regulator
PGKGLPEO_02250 4.3e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
PGKGLPEO_02251 3.5e-194 U protein localization to endoplasmic reticulum
PGKGLPEO_02252 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PGKGLPEO_02253 9.4e-91 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
PGKGLPEO_02254 1.4e-105 S HTH-like domain
PGKGLPEO_02255 1.3e-23 ymbI L Transposase
PGKGLPEO_02256 1.1e-62 K transcriptional
PGKGLPEO_02257 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PGKGLPEO_02258 2.5e-98 L Integrase
PGKGLPEO_02259 3.6e-84 S YqcI/YcgG family
PGKGLPEO_02260 3.3e-68 S Protein of unknown function (DUF2512)
PGKGLPEO_02261 0.0 O Belongs to the peptidase S8 family
PGKGLPEO_02262 5.8e-11 S Protein of unknown function (DUF1659)
PGKGLPEO_02263 9.8e-11 S Protein of unknown function (DUF2922)
PGKGLPEO_02264 6.5e-16 S YvrJ protein family
PGKGLPEO_02265 3.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
PGKGLPEO_02266 1.6e-219 EGP Major facilitator Superfamily
PGKGLPEO_02267 1.3e-168 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PGKGLPEO_02270 7.3e-59
PGKGLPEO_02271 4.1e-228 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGKGLPEO_02272 1.1e-122 yvfI K COG2186 Transcriptional regulators
PGKGLPEO_02273 1.4e-298 yvfH C L-lactate permease
PGKGLPEO_02274 5.1e-21 S Zinc-ribbon containing domain
PGKGLPEO_02275 6.8e-10 S double-stranded DNA endodeoxyribonuclease activity
PGKGLPEO_02276 5.2e-195 M1-600 T Putative diguanylate phosphodiesterase
PGKGLPEO_02277 4.6e-301 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PGKGLPEO_02278 8.4e-35 S LXG domain of WXG superfamily
PGKGLPEO_02279 8.1e-194 S LXG domain of WXG superfamily
PGKGLPEO_02285 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PGKGLPEO_02286 4.7e-53 D SMC domain-containing protein
PGKGLPEO_02287 2e-107
PGKGLPEO_02288 1.5e-160 galM 5.1.3.3 G Aldose 1-epimerase
PGKGLPEO_02289 1.1e-51
PGKGLPEO_02290 8.6e-76
PGKGLPEO_02291 1.2e-116 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_02292 8.9e-193 1.1.1.14 E Dehydrogenase
PGKGLPEO_02293 1e-192 yoaB EGP Major Facilitator Superfamily
PGKGLPEO_02294 2e-159 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PGKGLPEO_02295 2e-83 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
PGKGLPEO_02296 3.3e-114 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Bacterial fructose-1,6-bisphosphatase, glpX-encoded
PGKGLPEO_02297 4.7e-96 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PGKGLPEO_02298 7.2e-59 rpiB 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
PGKGLPEO_02299 1.3e-94 K DeoR C terminal sensor domain
PGKGLPEO_02300 3e-162 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
PGKGLPEO_02301 9.6e-206 narT P COG2223 Nitrate nitrite transporter
PGKGLPEO_02302 8.8e-122 narI 1.7.5.1 C nitrate reductase, gamma subunit
PGKGLPEO_02303 1.8e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
PGKGLPEO_02304 6.6e-308 narH 1.7.5.1 C Nitrate reductase, beta
PGKGLPEO_02305 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PGKGLPEO_02306 5.4e-43
PGKGLPEO_02307 3.5e-51
PGKGLPEO_02308 1.2e-68 S Hemerythrin HHE cation binding domain
PGKGLPEO_02309 6.6e-128 V COG1131 ABC-type multidrug transport system, ATPase component
PGKGLPEO_02311 1.3e-200 ybhR V COG0842 ABC-type multidrug transport system, permease component
PGKGLPEO_02312 1.6e-109 K Transcriptional regulator
PGKGLPEO_02313 6e-277 lysP E amino acid
PGKGLPEO_02314 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
PGKGLPEO_02316 2e-274 hsdM 2.1.1.72 V Type I restriction-modification system
PGKGLPEO_02317 3.8e-257 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PGKGLPEO_02318 6e-244 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PGKGLPEO_02319 2.4e-231 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
PGKGLPEO_02320 4.3e-126 yflK S protein conserved in bacteria
PGKGLPEO_02321 2.5e-08 ykyB S YkyB-like protein
PGKGLPEO_02322 2.8e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PGKGLPEO_02323 4.9e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PGKGLPEO_02324 5.3e-126 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PGKGLPEO_02325 1.7e-134 IQ Enoyl-(Acyl carrier protein) reductase
PGKGLPEO_02326 5.8e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PGKGLPEO_02327 3.5e-244 cytX F Permease for cytosine/purines, uracil, thiamine, allantoin
PGKGLPEO_02328 6.5e-78 3.6.1.55 F Belongs to the Nudix hydrolase family
PGKGLPEO_02329 1.6e-48 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
PGKGLPEO_02330 2.1e-236 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGKGLPEO_02331 2.8e-74 yqgC S protein conserved in bacteria
PGKGLPEO_02332 8.8e-265 ydbT S Bacterial PH domain
PGKGLPEO_02333 2.4e-62 L transposase, IS605 OrfB family
PGKGLPEO_02335 4e-10 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
PGKGLPEO_02336 2.2e-87 VPA1573 J acetyltransferase
PGKGLPEO_02337 7e-81 yvbK 3.1.3.25 K acetyltransferase
PGKGLPEO_02338 5.1e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
PGKGLPEO_02341 3.3e-09
PGKGLPEO_02342 6.3e-159 2.1.1.144, 2.1.1.197 S Methyltransferase domain
PGKGLPEO_02343 1.3e-90 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
PGKGLPEO_02344 5.6e-87 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
PGKGLPEO_02345 7.7e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PGKGLPEO_02346 1.4e-93 5.1.3.34 S oxidoreductase activity
PGKGLPEO_02349 1.7e-196 yrpB 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PGKGLPEO_02353 5.6e-70 E Glyoxalase
PGKGLPEO_02354 0.0 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
PGKGLPEO_02355 2.6e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PGKGLPEO_02356 1e-87 S Bacterial PH domain
PGKGLPEO_02357 1.3e-87 S AAA domain
PGKGLPEO_02358 6.2e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
PGKGLPEO_02359 5.9e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGKGLPEO_02360 4.3e-64 argO S Lysine exporter protein LysE YggA
PGKGLPEO_02361 2.4e-267 L Transposase
PGKGLPEO_02362 3e-299 lmrA 3.6.3.44 V ABC transporter
PGKGLPEO_02363 1.1e-99 K Iron dependent repressor, N-terminal DNA binding domain
PGKGLPEO_02364 9.8e-42
PGKGLPEO_02365 4.3e-261 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGKGLPEO_02366 1.4e-156 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PGKGLPEO_02367 2.4e-147 pdaA G deacetylase
PGKGLPEO_02368 2.6e-26 yfjT
PGKGLPEO_02369 5.9e-146 yfkD S YfkD-like protein
PGKGLPEO_02370 2e-173 cax P COG0387 Ca2 H antiporter
PGKGLPEO_02371 2e-219 yfkF EGP Major facilitator Superfamily
PGKGLPEO_02372 7.3e-147 yihY S Belongs to the UPF0761 family
PGKGLPEO_02373 7.3e-33 yfkK S Belongs to the UPF0435 family
PGKGLPEO_02374 7.5e-143 map 3.4.11.18 E Methionine aminopeptidase
PGKGLPEO_02375 1.6e-91 yfkM 3.5.1.124 S protease
PGKGLPEO_02376 3.1e-134 motB N Flagellar motor protein
PGKGLPEO_02377 1.2e-135 motA N flagellar motor
PGKGLPEO_02378 2.7e-58 yhdN S Domain of unknown function (DUF1992)
PGKGLPEO_02380 3.7e-60 yeaO S Protein of unknown function, DUF488
PGKGLPEO_02381 1.3e-227 EGP Major facilitator Superfamily
PGKGLPEO_02382 1.6e-145 dksA T COG1734 DnaK suppressor protein
PGKGLPEO_02383 5.8e-86 ykhA 3.1.2.20 I Acyl-CoA hydrolase
PGKGLPEO_02384 2.6e-183 mreB D Rod-share determining protein MreBH
PGKGLPEO_02385 3.8e-170 yuaG S protein conserved in bacteria
PGKGLPEO_02386 1.7e-91 yuaF OU Membrane protein implicated in regulation of membrane protease activity
PGKGLPEO_02387 6.7e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PGKGLPEO_02388 1.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
PGKGLPEO_02389 2.1e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PGKGLPEO_02390 4.2e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
PGKGLPEO_02391 4.8e-102 4.2.1.1 P Reversible hydration of carbon dioxide
PGKGLPEO_02393 3.1e-127 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PGKGLPEO_02394 9.7e-20
PGKGLPEO_02396 3e-279 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PGKGLPEO_02397 1.3e-55 yokK S SMI1-KNR4 cell-wall
PGKGLPEO_02398 9e-181 L Mu transposase, C-terminal
PGKGLPEO_02399 1.3e-63 L Mu transposase, C-terminal
PGKGLPEO_02400 2.8e-105 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
PGKGLPEO_02401 1.3e-142 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
PGKGLPEO_02402 5.2e-245 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
PGKGLPEO_02403 9e-124
PGKGLPEO_02404 6.9e-84 S Putative zinc-finger
PGKGLPEO_02405 5e-93 K Belongs to the sigma-70 factor family. ECF subfamily
PGKGLPEO_02406 2.1e-224 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
PGKGLPEO_02407 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
PGKGLPEO_02408 6.7e-259 NU cell adhesion
PGKGLPEO_02410 6e-180 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PGKGLPEO_02411 4.9e-171 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
PGKGLPEO_02412 6.3e-80 ycbG K FCD
PGKGLPEO_02413 0.0 ydaO E amino acid
PGKGLPEO_02414 1.6e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PGKGLPEO_02415 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PGKGLPEO_02416 1.2e-172 ydbI S AI-2E family transporter
PGKGLPEO_02417 1.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PGKGLPEO_02419 1.3e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
PGKGLPEO_02420 1.6e-109 gluC P ABC transporter
PGKGLPEO_02421 6.6e-117 glnP P ABC transporter
PGKGLPEO_02422 2.2e-69 K helix_turn_helix gluconate operon transcriptional repressor
PGKGLPEO_02423 2.2e-196 S Protein of unknown function (DUF1648)
PGKGLPEO_02424 3.3e-55 yodB K transcriptional
PGKGLPEO_02425 1.2e-233 S SNARE associated Golgi protein
PGKGLPEO_02426 4.2e-96 yngC S membrane-associated protein
PGKGLPEO_02427 9.5e-159 msrR K COG1316 Transcriptional regulator
PGKGLPEO_02428 4.5e-32 xylB 2.7.1.12, 2.7.1.17 G xylulose kinase
PGKGLPEO_02429 1.4e-74 yjbI S COG2346 Truncated hemoglobins
PGKGLPEO_02430 7e-161 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PGKGLPEO_02432 0.0 pepF E oligoendopeptidase F
PGKGLPEO_02433 1.1e-239 yjbF S Competence protein
PGKGLPEO_02434 1.2e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PGKGLPEO_02435 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PGKGLPEO_02436 2e-177 oppF E Belongs to the ABC transporter superfamily
PGKGLPEO_02437 2.3e-198 oppD P Belongs to the ABC transporter superfamily
PGKGLPEO_02438 3.7e-185 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGKGLPEO_02439 1.2e-153 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGKGLPEO_02440 0.0 dppE_1 E ABC transporter substrate-binding protein
PGKGLPEO_02441 1.2e-47 S Domain of unknown function (DUF3899)
PGKGLPEO_02442 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PGKGLPEO_02443 5.9e-148 yjbA S Belongs to the UPF0736 family
PGKGLPEO_02444 6.1e-150 rbsC G Belongs to the binding-protein-dependent transport system permease family
PGKGLPEO_02445 1.1e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PGKGLPEO_02446 1.4e-68 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PGKGLPEO_02447 1.1e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGKGLPEO_02448 8.9e-198 rbsR K transcriptional
PGKGLPEO_02451 5.7e-236 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PGKGLPEO_02453 7.3e-180 3.1.1.5 I Alpha beta hydrolase
PGKGLPEO_02455 3.1e-110 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PGKGLPEO_02456 2.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PGKGLPEO_02457 6.7e-212 2.7.1.2 GK ROK family
PGKGLPEO_02458 6.1e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_02459 1.6e-301 2.7.1.12, 2.7.1.17 G xylulose kinase
PGKGLPEO_02460 2e-239 yicJ G MFS/sugar transport protein
PGKGLPEO_02461 2.7e-196 EGP Major Facilitator Superfamily
PGKGLPEO_02462 1.4e-155 L Archaeal putative transposase ISC1217
PGKGLPEO_02463 1.9e-70 C Flavodoxin
PGKGLPEO_02464 4.1e-102 GM NAD(P)H-binding
PGKGLPEO_02465 5.4e-153 1.1.1.346 S Aldo/keto reductase family
PGKGLPEO_02466 9.5e-63 adhR K helix_turn_helix, mercury resistance
PGKGLPEO_02467 1.2e-62 S protein conserved in bacteria
PGKGLPEO_02468 4.3e-49
PGKGLPEO_02469 4.1e-90 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
PGKGLPEO_02473 2.3e-86 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PGKGLPEO_02474 3.9e-107 yjbK S protein conserved in bacteria
PGKGLPEO_02475 1.2e-56 yjbL S Belongs to the UPF0738 family
PGKGLPEO_02476 3.8e-122 yjbM 2.7.6.5 S GTP pyrophosphokinase
PGKGLPEO_02477 1.7e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PGKGLPEO_02478 4.3e-166 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PGKGLPEO_02479 3.6e-142 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PGKGLPEO_02480 3.3e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PGKGLPEO_02483 2.7e-84 cotY S Spore coat protein
PGKGLPEO_02484 8.4e-60 S Protein of unknown function (DUF1360)
PGKGLPEO_02486 6.6e-81 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PGKGLPEO_02487 1.5e-83 spoVAC S stage V sporulation protein AC
PGKGLPEO_02488 2.2e-190 spoVAD I Stage V sporulation protein AD
PGKGLPEO_02489 8.7e-57 spoVAE S stage V sporulation protein
PGKGLPEO_02491 8.3e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGKGLPEO_02492 6.9e-158 aacC 2.3.1.81 V aminoglycoside
PGKGLPEO_02493 4.1e-175 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_02494 0.0 aidB I Acyl-CoA dehydrogenase, middle domain
PGKGLPEO_02495 9.7e-291 6.2.1.3, 6.2.1.34 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGKGLPEO_02496 4.4e-62 cueR K transcriptional
PGKGLPEO_02497 1.8e-99 bioY S Biotin biosynthesis protein
PGKGLPEO_02499 1.3e-139 map 3.4.11.18 E Methionine aminopeptidase
PGKGLPEO_02500 1.1e-77 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PGKGLPEO_02501 6.4e-85
PGKGLPEO_02502 3.3e-211 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
PGKGLPEO_02503 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PGKGLPEO_02504 1.6e-171 corA P Mg2 transporter protein CorA family protein
PGKGLPEO_02507 1.2e-234 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGKGLPEO_02508 3.1e-46 yhdT S Sodium pantothenate symporter
PGKGLPEO_02509 5.7e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PGKGLPEO_02510 6.2e-290 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PGKGLPEO_02511 1.5e-17 S Protein of unknown function (DUF4064)
PGKGLPEO_02512 9.8e-146 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
PGKGLPEO_02513 8.4e-243 hom 1.1.1.3 E homoserine dehydrogenase
PGKGLPEO_02514 1.4e-195 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PGKGLPEO_02515 2.9e-165 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PGKGLPEO_02516 1.6e-140 P ABC transporter, ATP-binding protein
PGKGLPEO_02517 2.3e-184 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PGKGLPEO_02518 1.3e-140 ssuC_1 P binding-protein-dependent transport systems inner membrane component
PGKGLPEO_02519 4.5e-120 M1-594 S Thiamine-binding protein
PGKGLPEO_02521 8.6e-276 nylA 3.5.1.4 J Belongs to the amidase family
PGKGLPEO_02522 1.8e-81 S Heat induced stress protein YflT
PGKGLPEO_02523 6.6e-165 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PGKGLPEO_02524 2.7e-282 prpD 4.2.1.79 S 2-methylcitrate dehydratase
PGKGLPEO_02525 5.6e-211 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
PGKGLPEO_02526 9.1e-65 manO S Domain of unknown function (DUF956)
PGKGLPEO_02527 1.9e-169 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
PGKGLPEO_02528 3.6e-119 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
PGKGLPEO_02529 2.4e-178 manL 2.7.1.191 G PTS system mannose fructose sorbose family
PGKGLPEO_02530 2.4e-84 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
PGKGLPEO_02531 0.0 levR K PTS system fructose IIA component
PGKGLPEO_02532 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PGKGLPEO_02533 1.7e-201 pgl 3.1.1.31 G 6-phosphogluconolactonase
PGKGLPEO_02534 4.1e-47 yqgV S Thiamine-binding protein
PGKGLPEO_02535 0.0 pip S YhgE Pip N-terminal domain protein
PGKGLPEO_02536 5.4e-98 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
PGKGLPEO_02537 4.2e-162 expZ S ABC transporter
PGKGLPEO_02544 7.1e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
PGKGLPEO_02545 2.4e-56
PGKGLPEO_02546 5.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
PGKGLPEO_02547 2.5e-169 yhaQ S ABC transporter, ATP-binding protein
PGKGLPEO_02548 3.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
PGKGLPEO_02549 2.5e-258 pepC 3.4.22.40 E Papain family cysteine protease
PGKGLPEO_02550 3.2e-99 gph G MFS/sugar transport protein
PGKGLPEO_02551 1e-232 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGKGLPEO_02552 6.9e-206 S Bacterial protein of unknown function (DUF871)
PGKGLPEO_02553 5.6e-50 chbA 2.7.1.196, 2.7.1.205 G PTS cellobiose transporter subunit IIA
PGKGLPEO_02554 8.7e-51 licB 2.7.1.196, 2.7.1.205 G phosphotransferase system
PGKGLPEO_02555 0.0 2.7.1.202 K transcriptional regulator, MtlR
PGKGLPEO_02556 2.4e-215 EGP Major facilitator Superfamily
PGKGLPEO_02557 1.5e-191 yfmJ S N-terminal domain of oxidoreductase
PGKGLPEO_02558 1e-223 C acyl-CoA transferases carnitine dehydratase
PGKGLPEO_02559 2.3e-234 B4168_2380 1.3.99.32 I Acyl-CoA dehydrogenase, N-terminal domain
PGKGLPEO_02560 1.4e-53 S Domain of unknown function (DUF3870)
PGKGLPEO_02562 2.7e-53 S Domain of unknown function (DUF5085)
PGKGLPEO_02563 1.2e-15
PGKGLPEO_02564 5.2e-134 L COG2801 Transposase and inactivated derivatives
PGKGLPEO_02565 2.5e-13 S double-stranded DNA endodeoxyribonuclease activity
PGKGLPEO_02566 3.5e-19 S Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
PGKGLPEO_02567 1.2e-291
PGKGLPEO_02568 2.7e-43 S Stage II sporulation protein M
PGKGLPEO_02569 3.3e-121 V ATPases associated with a variety of cellular activities
PGKGLPEO_02571 3.6e-101 S ABC-2 family transporter protein
PGKGLPEO_02572 8.1e-120 V AAA domain, putative AbiEii toxin, Type IV TA system
PGKGLPEO_02574 1.7e-163
PGKGLPEO_02575 9.6e-152 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PGKGLPEO_02576 3.9e-62 yojF S Protein of unknown function (DUF1806)
PGKGLPEO_02577 1.1e-129 bshB2 S deacetylase
PGKGLPEO_02578 9.1e-175 ycsE S hydrolases of the HAD superfamily
PGKGLPEO_02579 0.0 recQ 3.6.4.12 L DNA helicase
PGKGLPEO_02580 3.4e-228 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
PGKGLPEO_02581 1.8e-153 ybbH_2 K Transcriptional regulator
PGKGLPEO_02582 1.1e-153 S Alpha/beta hydrolase of unknown function (DUF915)
PGKGLPEO_02583 3.1e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGKGLPEO_02584 4.9e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PGKGLPEO_02585 1.6e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PGKGLPEO_02586 4.4e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PGKGLPEO_02587 0.0 carB 6.3.5.5 F Belongs to the CarB family
PGKGLPEO_02588 7.7e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PGKGLPEO_02589 2.7e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PGKGLPEO_02590 3.6e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PGKGLPEO_02591 8.7e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PGKGLPEO_02592 1e-178 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PGKGLPEO_02593 2.2e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PGKGLPEO_02595 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PGKGLPEO_02596 2.5e-65 divIVA D Cell division initiation protein
PGKGLPEO_02597 1.7e-145 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
PGKGLPEO_02598 2.5e-40 yggT S membrane
PGKGLPEO_02599 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PGKGLPEO_02600 7.8e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PGKGLPEO_02601 3.9e-161 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
PGKGLPEO_02602 2.2e-72 yocH CBM50 M 3D domain
PGKGLPEO_02603 1.9e-43 ylmC S sporulation protein
PGKGLPEO_02604 1.5e-138 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGKGLPEO_02605 1.7e-112 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGKGLPEO_02606 5.7e-169 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PGKGLPEO_02607 1.2e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGKGLPEO_02608 2e-220 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PGKGLPEO_02609 2.4e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PGKGLPEO_02610 3.5e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PGKGLPEO_02611 1.6e-189 spoVE D Belongs to the SEDS family
PGKGLPEO_02612 7.4e-258 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PGKGLPEO_02613 8.4e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PGKGLPEO_02614 1.7e-78 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PGKGLPEO_02615 1.8e-278 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGKGLPEO_02616 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
PGKGLPEO_02617 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PGKGLPEO_02618 1.7e-39 ftsL D Essential cell division protein
PGKGLPEO_02619 1.3e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PGKGLPEO_02620 2e-79 mraZ K Belongs to the MraZ family
PGKGLPEO_02621 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PGKGLPEO_02622 3.5e-160 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGKGLPEO_02623 2.3e-92 ylbP K n-acetyltransferase
PGKGLPEO_02624 3.3e-81 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PGKGLPEO_02625 1e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PGKGLPEO_02626 7.7e-97 yceD S metal-binding, possibly nucleic acid-binding protein
PGKGLPEO_02627 1.1e-242 ylbM S Belongs to the UPF0348 family
PGKGLPEO_02628 7.4e-189 ylbL T Belongs to the peptidase S16 family
PGKGLPEO_02629 2.4e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
PGKGLPEO_02630 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
PGKGLPEO_02631 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PGKGLPEO_02632 1.3e-108 rsmD 2.1.1.171 L Methyltransferase
PGKGLPEO_02633 2e-67 S Methylthioribose kinase
PGKGLPEO_02634 5.3e-46 ylbG S UPF0298 protein
PGKGLPEO_02635 1.3e-73 ylbF S Belongs to the UPF0342 family
PGKGLPEO_02636 5.4e-65
PGKGLPEO_02637 1.4e-37 ylbE S YlbE-like protein
PGKGLPEO_02638 1.7e-69 ylbD S Putative coat protein
PGKGLPEO_02639 4.5e-85 yiiD Q protein, possibly involved in aromatic compounds catabolism
PGKGLPEO_02640 3.6e-180 ylbC S protein with SCP PR1 domains
PGKGLPEO_02641 7.4e-64 ylbA S YugN-like family
PGKGLPEO_02642 3e-176 ctaG S cytochrome c oxidase
PGKGLPEO_02643 1.4e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PGKGLPEO_02644 1.2e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PGKGLPEO_02645 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PGKGLPEO_02646 2.6e-205 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PGKGLPEO_02647 4.5e-166 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PGKGLPEO_02648 3.6e-174 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PGKGLPEO_02649 2e-217 ftsW D Belongs to the SEDS family
PGKGLPEO_02650 1.5e-43 ylaN S Belongs to the UPF0358 family
PGKGLPEO_02651 2.6e-88 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PGKGLPEO_02652 5.6e-250 phoH T ATPase related to phosphate starvation-inducible protein PhoH
PGKGLPEO_02653 1.2e-52 ylaH S YlaH-like protein
PGKGLPEO_02654 0.0 typA T GTP-binding protein TypA
PGKGLPEO_02655 6e-25 S Family of unknown function (DUF5325)
PGKGLPEO_02656 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
PGKGLPEO_02657 3.1e-24
PGKGLPEO_02658 1.5e-117 yktB S Belongs to the UPF0637 family
PGKGLPEO_02659 1.1e-46 yktA S Belongs to the UPF0223 family
PGKGLPEO_02660 1.2e-277 speA 4.1.1.19 E Arginine
PGKGLPEO_02662 2e-33
PGKGLPEO_02663 6.3e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PGKGLPEO_02664 4.1e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGKGLPEO_02665 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PGKGLPEO_02666 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PGKGLPEO_02667 1.5e-29 ykzG S Belongs to the UPF0356 family
PGKGLPEO_02668 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGKGLPEO_02669 1.8e-18 S YhfH-like protein
PGKGLPEO_02670 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PGKGLPEO_02671 4.7e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PGKGLPEO_02672 4.1e-158 ccpC K Transcriptional regulator
PGKGLPEO_02673 6.5e-78 ykuL S CBS domain
PGKGLPEO_02674 5.8e-39 ykuJ S protein conserved in bacteria
PGKGLPEO_02675 3.9e-170 3.5.1.4 C Acetamidase
PGKGLPEO_02676 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_02677 2e-32
PGKGLPEO_02678 0.0 T Diguanylate cyclase
PGKGLPEO_02679 0.0 ydgH S drug exporters of the RND superfamily
PGKGLPEO_02680 3.1e-86 ykyB S YkyB-like protein
PGKGLPEO_02681 1e-162 cheV 2.7.13.3 T Chemotaxis protein CheV
PGKGLPEO_02682 6.6e-215 patA 2.6.1.1 E Aminotransferase
PGKGLPEO_02683 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PGKGLPEO_02684 1.4e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_02685 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGKGLPEO_02686 3.2e-40 ptsH G phosphocarrier protein HPr
PGKGLPEO_02687 7e-28
PGKGLPEO_02688 2.5e-26 ykvS S protein conserved in bacteria
PGKGLPEO_02689 2.7e-106 S Abortive infection protein
PGKGLPEO_02690 9.5e-181 ykvI S membrane
PGKGLPEO_02691 0.0 clpE O Belongs to the ClpA ClpB family
PGKGLPEO_02693 3.3e-71 XK27_09985 S Protein of unknown function (DUF1232)
PGKGLPEO_02694 4.4e-85 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PGKGLPEO_02695 6.3e-290 kinE 2.7.13.3 T Histidine kinase
PGKGLPEO_02697 7.3e-19 S Stage 0 Sporulation Regulatory protein
PGKGLPEO_02698 2.1e-28 sspD S small acid-soluble spore protein
PGKGLPEO_02699 4.7e-143 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PGKGLPEO_02700 3.8e-84
PGKGLPEO_02701 3.5e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PGKGLPEO_02702 3.1e-206 pilS 2.7.13.3 T Histidine kinase
PGKGLPEO_02703 6.7e-184 mocA S Oxidoreductase
PGKGLPEO_02704 2.8e-73 dps P Ferritin-like domain
PGKGLPEO_02705 3e-123 S membrane transporter protein
PGKGLPEO_02706 3.7e-216 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PGKGLPEO_02707 1.9e-74 nsrR K Transcriptional regulator
PGKGLPEO_02708 5.6e-138 tesE Q COG3971 2-keto-4-pentenoate hydratase
PGKGLPEO_02709 1.8e-46
PGKGLPEO_02710 4.5e-174 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGKGLPEO_02711 1.3e-97 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PGKGLPEO_02712 8.2e-43 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PGKGLPEO_02713 4.1e-259 proP EGP Transporter
PGKGLPEO_02714 1.1e-145 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PGKGLPEO_02715 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
PGKGLPEO_02716 4.4e-89 yrhD S Protein of unknown function (DUF1641)
PGKGLPEO_02717 2.1e-193 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PGKGLPEO_02718 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PGKGLPEO_02719 3e-34 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PGKGLPEO_02720 3.9e-78 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
PGKGLPEO_02721 3.4e-88 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PGKGLPEO_02722 7.1e-239 moeA 2.10.1.1 H molybdopterin
PGKGLPEO_02723 6.1e-120 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PGKGLPEO_02724 1.7e-82 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PGKGLPEO_02725 5.1e-187 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PGKGLPEO_02726 4.1e-130 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
PGKGLPEO_02727 1.1e-101 P COG4149 ABC-type molybdate transport system, permease component
PGKGLPEO_02728 2e-122 modA P Molybdenum ABC transporter
PGKGLPEO_02729 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PGKGLPEO_02730 5.2e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PGKGLPEO_02731 5.5e-118 acuB S Acetoin utilization protein AcuB
PGKGLPEO_02732 5.4e-233 acuC BQ histone deacetylase
PGKGLPEO_02733 1.3e-182 ccpA K catabolite control protein A
PGKGLPEO_02734 3.8e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PGKGLPEO_02735 4.2e-33 XK27_07760 S COG4980 Gas vesicle protein
PGKGLPEO_02736 2.8e-51 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PGKGLPEO_02737 1.1e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PGKGLPEO_02738 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PGKGLPEO_02739 1.2e-69 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PGKGLPEO_02740 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGKGLPEO_02741 6.9e-147 ytpQ S Belongs to the UPF0354 family
PGKGLPEO_02742 5.5e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PGKGLPEO_02743 5e-34 rsbU 3.1.3.3 T response regulator
PGKGLPEO_02744 6.8e-145 rsbU 3.1.3.3 T response regulator
PGKGLPEO_02745 3.6e-154 cheR 2.1.1.80 NT chemotaxis
PGKGLPEO_02746 0.0 T PhoQ Sensor
PGKGLPEO_02747 1.2e-197 EGP Transmembrane secretion effector
PGKGLPEO_02749 3.8e-33
PGKGLPEO_02750 4.2e-92 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PGKGLPEO_02751 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PGKGLPEO_02752 3.3e-52 ytzB S small secreted protein
PGKGLPEO_02753 7.6e-103 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
PGKGLPEO_02754 8.6e-215 araR K transcriptional
PGKGLPEO_02755 3.4e-214 NT chemotaxis protein
PGKGLPEO_02756 1.4e-124 plsB 2.3.1.15 I Acyl-transferase
PGKGLPEO_02757 1e-201 2.4.1.83 GT2 M Glycosyl transferase family 2
PGKGLPEO_02758 1.9e-136 IQ Enoyl-(Acyl carrier protein) reductase
PGKGLPEO_02759 1.3e-73 yuiD S protein conserved in bacteria
PGKGLPEO_02760 5e-215 solA 1.5.3.1 E FAD dependent oxidoreductase
PGKGLPEO_02761 1.5e-219 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
PGKGLPEO_02762 1.7e-279 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGKGLPEO_02763 7.8e-171 4.3.1.12 E ornithine cyclodeaminase
PGKGLPEO_02766 3.7e-182 yugO P COG1226 Kef-type K transport systems
PGKGLPEO_02767 7.9e-260 pgi 5.3.1.9 G Belongs to the GPI family
PGKGLPEO_02768 6.7e-34 yuzA S Domain of unknown function (DUF378)
PGKGLPEO_02769 1.5e-85 K Bacterial transcription activator, effector binding domain
PGKGLPEO_02772 7.2e-65 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
PGKGLPEO_02773 3.4e-29 K Helix-turn-helix XRE-family like proteins
PGKGLPEO_02774 8e-196 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PGKGLPEO_02775 1.6e-165 S reductase
PGKGLPEO_02776 9.9e-160 dkgB S Aldo/keto reductase family
PGKGLPEO_02778 4.2e-239 S protein conserved in bacteria
PGKGLPEO_02780 2.1e-111 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGKGLPEO_02781 9.9e-67 kapB G Kinase associated protein B
PGKGLPEO_02782 3.4e-143
PGKGLPEO_02783 1e-209 hcnC 1.4.99.5 E FAD dependent oxidoreductase
PGKGLPEO_02784 1.1e-52 thcD 1.14.13.111, 1.18.1.3, 1.7.1.15 S BFD-like [2Fe-2S] binding domain
PGKGLPEO_02785 1.1e-206 C HI0933-like protein
PGKGLPEO_02786 4.6e-57 1.2.5.3, 1.3.99.16 C 2 iron, 2 sulfur cluster binding
PGKGLPEO_02787 3e-13 S transposase or invertase
PGKGLPEO_02788 2.5e-20 S transposase or invertase
PGKGLPEO_02790 1.1e-226 NT chemotaxis protein
PGKGLPEO_02792 1.3e-31
PGKGLPEO_02793 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
PGKGLPEO_02795 7.4e-86 S Protein of unknown function (DUF1641)
PGKGLPEO_02796 1.3e-07 S Heavy-metal-associated domain
PGKGLPEO_02798 2.4e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PGKGLPEO_02799 8.7e-40 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PGKGLPEO_02800 1.2e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PGKGLPEO_02801 9.6e-186 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PGKGLPEO_02802 2.2e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PGKGLPEO_02803 6.9e-120 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PGKGLPEO_02804 5e-303 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
PGKGLPEO_02805 7.9e-241 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PGKGLPEO_02806 2.5e-28 secG U Preprotein translocase subunit SecG
PGKGLPEO_02807 4.8e-142 est 3.1.1.1 S Carboxylesterase
PGKGLPEO_02808 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PGKGLPEO_02809 5e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PGKGLPEO_02811 5.8e-11 S transposase or invertase
PGKGLPEO_02812 3.3e-198 yjjL G Major facilitator superfamily
PGKGLPEO_02813 9.8e-146
PGKGLPEO_02814 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGKGLPEO_02815 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGKGLPEO_02816 1.9e-71 yccU S CoA-binding protein
PGKGLPEO_02817 9.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PGKGLPEO_02818 3.7e-53 yneR S Belongs to the HesB IscA family
PGKGLPEO_02819 1.1e-52 yneQ
PGKGLPEO_02820 2.2e-75 yneP S thioesterase
PGKGLPEO_02821 4.1e-31 tlp S Belongs to the Tlp family
PGKGLPEO_02822 1e-19 sspN S Small acid-soluble spore protein N family
PGKGLPEO_02824 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PGKGLPEO_02825 4.4e-18 sspO S Belongs to the SspO family
PGKGLPEO_02826 7.1e-239 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PGKGLPEO_02827 1e-38
PGKGLPEO_02828 1.9e-18 sspP S Belongs to the SspP family
PGKGLPEO_02829 1.4e-08 S membrane
PGKGLPEO_02830 6.6e-113 M lytic transglycosylase activity
PGKGLPEO_02831 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGKGLPEO_02832 4.4e-110 M effector of murein hydrolase
PGKGLPEO_02833 7.6e-62 S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PGKGLPEO_02834 7.2e-43 S Small, acid-soluble spore proteins, alpha/beta type
PGKGLPEO_02835 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
PGKGLPEO_02836 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
PGKGLPEO_02837 2.1e-49 iscA S Heme biosynthesis protein HemY
PGKGLPEO_02838 1.4e-237 ywoD EGP Major facilitator superfamily
PGKGLPEO_02841 1.8e-142
PGKGLPEO_02842 7.4e-200 yetN S Protein of unknown function (DUF3900)
PGKGLPEO_02843 6.8e-238 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
PGKGLPEO_02844 1.3e-16
PGKGLPEO_02845 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
PGKGLPEO_02846 2.6e-198 ybcL EGP Major facilitator Superfamily
PGKGLPEO_02847 6.3e-69 ybzH K Helix-turn-helix domain
PGKGLPEO_02848 0.0
PGKGLPEO_02849 9.6e-102 S Protein of unknown function (DUF1672)
PGKGLPEO_02850 1.1e-86 S Protein of unknown function (DUF1672)
PGKGLPEO_02852 1.6e-11
PGKGLPEO_02853 1.2e-181 T PhoQ Sensor
PGKGLPEO_02854 5.2e-101 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGKGLPEO_02855 2e-21 S Protein of unknown function (DUF1093)
PGKGLPEO_02856 1.6e-102 S ABC-2 family transporter protein
PGKGLPEO_02857 1.1e-82 S ABC-2 family transporter protein
PGKGLPEO_02858 9.7e-82 bcrA V Bacitracin ABC transporter ATP-binding protein
PGKGLPEO_02859 3.8e-46 bcrA V Bacitracin ABC transporter ATP-binding protein
PGKGLPEO_02860 4.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGKGLPEO_02861 3.2e-181 bceS 2.7.13.3 T Signal transduction histidine kinase
PGKGLPEO_02862 2e-135 bceA V ABC transporter, ATP-binding protein
PGKGLPEO_02863 0.0 bceB V ABC transporter (permease)
PGKGLPEO_02864 5.8e-46 yxiS
PGKGLPEO_02865 6.9e-44 S Protein of unknown function (DUF1292)
PGKGLPEO_02866 5.3e-162 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
PGKGLPEO_02867 9.4e-118 folE 3.5.4.16 H GTP cyclohydrolase
PGKGLPEO_02868 2.7e-31 cspB K Cold shock
PGKGLPEO_02870 2.1e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGKGLPEO_02871 4.7e-24 S ATP synthase, subunit b
PGKGLPEO_02872 0.0 ubiB S ABC1 family
PGKGLPEO_02873 8.6e-218 yeaN P COG2807 Cyanate permease
PGKGLPEO_02874 3.6e-48 yxcD S Protein of unknown function (DUF2653)
PGKGLPEO_02875 1e-17
PGKGLPEO_02876 3e-136 ykrK S Domain of unknown function (DUF1836)
PGKGLPEO_02877 2.9e-122 P COG0569 K transport systems, NAD-binding component
PGKGLPEO_02878 2e-220 ktrB P COG0168 Trk-type K transport systems, membrane components
PGKGLPEO_02879 2.1e-174 rarD S -transporter
PGKGLPEO_02880 1.4e-239 yedE S Sulphur transport
PGKGLPEO_02881 5.9e-41 yedF O Belongs to the sulfur carrier protein TusA family
PGKGLPEO_02882 2.3e-119 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
PGKGLPEO_02883 6.6e-139 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGKGLPEO_02884 1.1e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PGKGLPEO_02885 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PGKGLPEO_02886 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PGKGLPEO_02887 2.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGKGLPEO_02888 8.1e-111 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PGKGLPEO_02889 2.3e-212 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PGKGLPEO_02890 3.3e-69 S CHY zinc finger
PGKGLPEO_02891 7.4e-92
PGKGLPEO_02892 1.2e-99
PGKGLPEO_02895 5.2e-36 S Transcriptional Coactivator p15 (PC4)
PGKGLPEO_02896 6e-219 O Peptidase S53
PGKGLPEO_02897 4e-237 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
PGKGLPEO_02898 4.6e-45
PGKGLPEO_02899 1.3e-110 yjlB S Cupin domain
PGKGLPEO_02900 3.1e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
PGKGLPEO_02901 2e-137 yflN_1 S Metallo-beta-lactamase superfamily
PGKGLPEO_02902 6.1e-298 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
PGKGLPEO_02903 1.4e-303 comM O Mg chelatase subunit ChlI
PGKGLPEO_02904 1.1e-149 S transposase or invertase
PGKGLPEO_02905 4.6e-21
PGKGLPEO_02906 2.7e-202 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PGKGLPEO_02907 2.4e-248 csbC EGP Major facilitator Superfamily
PGKGLPEO_02908 3e-130 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
PGKGLPEO_02909 1.5e-11 S transposase or invertase
PGKGLPEO_02910 2.6e-132 U AAA domain
PGKGLPEO_02912 5.1e-74 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
PGKGLPEO_02913 1.8e-34 sagB C Nitroreductase family
PGKGLPEO_02914 1.6e-09
PGKGLPEO_02916 2.8e-18 O Zn-dependent protease
PGKGLPEO_02917 1.6e-74 EGP Major facilitator Superfamily
PGKGLPEO_02918 1.2e-277 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
PGKGLPEO_02919 1.4e-189 T HD domain
PGKGLPEO_02921 7.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PGKGLPEO_02922 6.4e-96 S Belongs to the UPF0312 family
PGKGLPEO_02923 3.6e-131 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
PGKGLPEO_02924 6.6e-122 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PGKGLPEO_02925 1.8e-213 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGKGLPEO_02926 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PGKGLPEO_02927 1.2e-290 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PGKGLPEO_02928 1.4e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
PGKGLPEO_02929 2.2e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PGKGLPEO_02930 2.5e-30 K Cro/C1-type HTH DNA-binding domain
PGKGLPEO_02933 1.4e-18
PGKGLPEO_02934 1.2e-31
PGKGLPEO_02936 0.0 helD 3.6.4.12 L DNA helicase
PGKGLPEO_02937 2.6e-183 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PGKGLPEO_02938 5e-238 citH C Citrate transporter
PGKGLPEO_02939 1.6e-120 citT T response regulator
PGKGLPEO_02940 5.4e-292 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PGKGLPEO_02941 3.4e-233 amt P Ammonium transporter
PGKGLPEO_02942 6e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
PGKGLPEO_02943 7.4e-253 E Amino acid permease
PGKGLPEO_02944 7.7e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PGKGLPEO_02945 1.5e-272 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PGKGLPEO_02946 2.7e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PGKGLPEO_02947 8.2e-252 E amino acid
PGKGLPEO_02948 1.5e-250 H HemY protein
PGKGLPEO_02949 1.2e-202 potD E COG0687 Spermidine putrescine-binding periplasmic protein
PGKGLPEO_02950 5.4e-139 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
PGKGLPEO_02951 1.1e-139 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
PGKGLPEO_02952 1.2e-210 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PGKGLPEO_02953 7.3e-98 puuR K Cupin domain
PGKGLPEO_02954 6.6e-276 lysP E amino acid
PGKGLPEO_02955 3.3e-275 dtpT E amino acid peptide transporter
PGKGLPEO_02956 1.7e-17
PGKGLPEO_02957 6.5e-254 E COG1113 Gamma-aminobutyrate permease and related permeases
PGKGLPEO_02958 1.2e-97 ydjA C Nitroreductase family
PGKGLPEO_02959 3.5e-174 iolS C Aldo keto reductase
PGKGLPEO_02960 1.2e-83 cotF M Spore coat protein
PGKGLPEO_02961 1.4e-93 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
PGKGLPEO_02962 4.5e-93 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
PGKGLPEO_02963 3.4e-236 G Major Facilitator Superfamily
PGKGLPEO_02964 1.4e-178 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
PGKGLPEO_02965 7.8e-140 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
PGKGLPEO_02966 8.6e-42 L Transposase, IS4 family protein
PGKGLPEO_02967 9e-89 1.4.3.5 S Pyridoxamine 5'phosphate oxidase-like, FMN-binding
PGKGLPEO_02968 7.3e-71 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
PGKGLPEO_02969 3.8e-137 yokF 3.1.31.1 L RNA catabolic process
PGKGLPEO_02970 4.3e-37 yhjE S protein conserved in bacteria
PGKGLPEO_02971 2.7e-48 P Rhodanese domain protein
PGKGLPEO_02972 1.4e-240 P Voltage gated chloride channel
PGKGLPEO_02977 4.1e-175 nodB1 G deacetylase
PGKGLPEO_02978 7.7e-11 recN L Putative cell-wall binding lipoprotein
PGKGLPEO_02980 8.2e-14 yhjQ C COG1145 Ferredoxin
PGKGLPEO_02982 6.1e-266 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGKGLPEO_02983 5.1e-27 yhjC S Protein of unknown function (DUF3311)
PGKGLPEO_02984 3e-223 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PGKGLPEO_02985 2e-73 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGKGLPEO_02986 1.5e-68 lrpC K Transcriptional regulator
PGKGLPEO_02987 8.4e-57 S protein conserved in bacteria
PGKGLPEO_02988 2.4e-30 P Copper resistance protein CopZ
PGKGLPEO_02989 0.0 copA 3.6.3.54 P P-type ATPase
PGKGLPEO_02990 1.7e-55 EGP Major facilitator Superfamily
PGKGLPEO_02991 3.1e-166 S Protein of unknown function (DUF1646)
PGKGLPEO_02992 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PGKGLPEO_02993 2e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PGKGLPEO_02994 1.3e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PGKGLPEO_02995 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
PGKGLPEO_02996 5.2e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PGKGLPEO_02997 6.7e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PGKGLPEO_02998 1.8e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PGKGLPEO_02999 6.4e-213 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGKGLPEO_03000 8.6e-219 pbuO_1 S permease
PGKGLPEO_03001 8.8e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PGKGLPEO_03002 8e-166 S Protein of unknown function (DUF979)
PGKGLPEO_03003 6.5e-117 S Protein of unknown function (DUF969)
PGKGLPEO_03004 2.6e-135 ycsF S Belongs to the UPF0271 (lamB) family
PGKGLPEO_03005 1.2e-180 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
PGKGLPEO_03006 2.4e-135 kipI 3.5.1.54, 6.3.4.6 E Allophanate hydrolase subunit 1
PGKGLPEO_03007 1.2e-214 EGP Major facilitator Superfamily
PGKGLPEO_03008 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
PGKGLPEO_03009 3.7e-131 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PGKGLPEO_03010 7.6e-115 artQ E COG0765 ABC-type amino acid transport system, permease component
PGKGLPEO_03011 2e-135 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGKGLPEO_03012 2.2e-218 hipO3 3.5.1.47 S amidohydrolase
PGKGLPEO_03013 4.3e-113 mdeA 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PGKGLPEO_03014 1.2e-47
PGKGLPEO_03015 1.1e-178 corA P Mg2 transporter protein
PGKGLPEO_03016 5.8e-112 E Lysine exporter protein LysE YggA
PGKGLPEO_03017 1.6e-244 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
PGKGLPEO_03018 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGKGLPEO_03019 9.1e-107 yocH CBM50 M COG1388 FOG LysM repeat
PGKGLPEO_03020 2.5e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
PGKGLPEO_03021 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
PGKGLPEO_03022 6.7e-164 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
PGKGLPEO_03023 1.8e-104 thiT S Proton-coupled thiamine transporter YuaJ
PGKGLPEO_03024 1.6e-128 yoqW S Belongs to the SOS response-associated peptidase family
PGKGLPEO_03025 3.5e-193 yceA S Belongs to the UPF0176 family
PGKGLPEO_03026 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGKGLPEO_03027 1.5e-161 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PGKGLPEO_03029 7.5e-114 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGKGLPEO_03030 5.9e-92 rok S Repressor of ComK
PGKGLPEO_03031 2.9e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
PGKGLPEO_03032 7.3e-202 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PGKGLPEO_03033 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PGKGLPEO_03034 2.4e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
PGKGLPEO_03035 1.2e-255 arlS 2.7.13.3 T Histidine kinase
PGKGLPEO_03036 1.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGKGLPEO_03037 8.8e-229 ymfD EGP Major facilitator Superfamily
PGKGLPEO_03038 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
PGKGLPEO_03039 5.4e-59 4.4.1.5 E lactoylglutathione lyase activity
PGKGLPEO_03040 2.3e-104 K Transcriptional regulator
PGKGLPEO_03041 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PGKGLPEO_03043 1.8e-105 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
PGKGLPEO_03044 4.6e-133 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PGKGLPEO_03045 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
PGKGLPEO_03046 8.3e-190 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PGKGLPEO_03048 2.4e-248 norM V Multidrug efflux pump
PGKGLPEO_03049 1e-99 ykwD J protein with SCP PR1 domains
PGKGLPEO_03050 3.9e-67 ypoP K transcriptional
PGKGLPEO_03051 6.4e-279 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PGKGLPEO_03052 6.9e-147 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PGKGLPEO_03054 1.3e-24 yozD S YozD-like protein
PGKGLPEO_03055 1.5e-115 yodN
PGKGLPEO_03056 1.2e-35 yozE S Belongs to the UPF0346 family
PGKGLPEO_03057 6e-199 NT CHASE3 domain
PGKGLPEO_03058 9e-16 S Protein of unknown function (Tiny_TM_bacill)
PGKGLPEO_03059 7.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PGKGLPEO_03060 1.1e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGKGLPEO_03061 1.8e-275 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
PGKGLPEO_03062 4.6e-97 ypmS S protein conserved in bacteria
PGKGLPEO_03063 4.7e-140 ypmR E COG2755 Lysophospholipase L1 and related esterases
PGKGLPEO_03064 4.2e-110 hlyIII S protein, Hemolysin III
PGKGLPEO_03065 3.9e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PGKGLPEO_03066 3.1e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PGKGLPEO_03067 8.1e-105 ypjP S YpjP-like protein
PGKGLPEO_03068 5.6e-74 yphP S Belongs to the UPF0403 family
PGKGLPEO_03069 8.3e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
PGKGLPEO_03070 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PGKGLPEO_03071 1.9e-118 ypgQ S phosphohydrolase
PGKGLPEO_03072 4.4e-83
PGKGLPEO_03073 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PGKGLPEO_03074 1.2e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PGKGLPEO_03075 1.2e-31 cspD K Cold-shock protein
PGKGLPEO_03076 3.6e-27 ypeQ S Zinc-finger
PGKGLPEO_03078 1.1e-167 polA 2.7.7.7 L 5'3' exonuclease
PGKGLPEO_03079 5.2e-245 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PGKGLPEO_03080 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGKGLPEO_03081 4.2e-175 spoVK O stage V sporulation protein K
PGKGLPEO_03083 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PGKGLPEO_03084 2e-194 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PGKGLPEO_03087 4.1e-22 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
PGKGLPEO_03088 5.5e-40 yhjA S Excalibur calcium-binding domain
PGKGLPEO_03089 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PGKGLPEO_03090 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PGKGLPEO_03091 6.2e-99 cotE S Outer spore coat protein E (CotE)
PGKGLPEO_03092 2.1e-49 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PGKGLPEO_03093 8.9e-300 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PGKGLPEO_03094 1.9e-261 patA 2.6.1.11, 2.6.1.17, 2.6.1.82 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PGKGLPEO_03095 5.8e-288 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
PGKGLPEO_03096 0.0 KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PGKGLPEO_03097 3.3e-250 E Amino acid permease
PGKGLPEO_03098 3.1e-250 yegQ O COG0826 Collagenase and related proteases
PGKGLPEO_03099 6e-171 yegQ O Peptidase U32
PGKGLPEO_03100 3.3e-37 spoVS S Stage V sporulation protein S
PGKGLPEO_03101 6.5e-153 ymdB S protein conserved in bacteria
PGKGLPEO_03102 2.5e-217 rny S Endoribonuclease that initiates mRNA decay
PGKGLPEO_03103 2.1e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PGKGLPEO_03104 2e-225 cinA 3.5.1.42 S Belongs to the CinA family
PGKGLPEO_03105 4.6e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGKGLPEO_03106 2.5e-154 ymfM S protein conserved in bacteria
PGKGLPEO_03107 9.9e-146 ymfK S Protein of unknown function (DUF3388)
PGKGLPEO_03108 6.4e-41 ymfJ S Protein of unknown function (DUF3243)
PGKGLPEO_03109 1.3e-128 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PGKGLPEO_03110 1.2e-244 ymfH S zinc protease
PGKGLPEO_03111 1.8e-237 ymfF S Peptidase M16
PGKGLPEO_03112 4.9e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
PGKGLPEO_03113 2e-186 yufP S Belongs to the binding-protein-dependent transport system permease family
PGKGLPEO_03114 7.8e-288 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PGKGLPEO_03115 1.5e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
PGKGLPEO_03116 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PGKGLPEO_03117 3.3e-35 S YlzJ-like protein
PGKGLPEO_03118 2e-132 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
PGKGLPEO_03119 0.0 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGKGLPEO_03120 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGKGLPEO_03121 3.6e-227 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PGKGLPEO_03122 9.6e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGKGLPEO_03123 7.4e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PGKGLPEO_03124 1.3e-190 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
PGKGLPEO_03125 6.2e-38 ymxH S YlmC YmxH family
PGKGLPEO_03126 5.2e-234 pepR S Belongs to the peptidase M16 family
PGKGLPEO_03127 5.2e-209 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
PGKGLPEO_03128 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PGKGLPEO_03129 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PGKGLPEO_03130 3.8e-184 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PGKGLPEO_03131 5.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PGKGLPEO_03132 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PGKGLPEO_03133 8.6e-44 ylxP S protein conserved in bacteria
PGKGLPEO_03134 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PGKGLPEO_03135 2.9e-48 ylxQ J ribosomal protein
PGKGLPEO_03136 4.8e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
PGKGLPEO_03137 2.8e-224 nusA K Participates in both transcription termination and antitermination
PGKGLPEO_03138 7.1e-83 rimP S Required for maturation of 30S ribosomal subunits
PGKGLPEO_03139 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGKGLPEO_03140 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PGKGLPEO_03141 7.4e-236 rasP M zinc metalloprotease
PGKGLPEO_03142 1.6e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PGKGLPEO_03143 1.8e-142 cdsA 2.7.7.41 S Belongs to the CDS family
PGKGLPEO_03144 1.6e-148 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PGKGLPEO_03145 9e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PGKGLPEO_03146 1.5e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PGKGLPEO_03147 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PGKGLPEO_03148 6.2e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
PGKGLPEO_03149 1.4e-85 ylxL
PGKGLPEO_03150 1.1e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGKGLPEO_03151 3.1e-84 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PGKGLPEO_03152 1.1e-113 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PGKGLPEO_03153 8.2e-70 cheW NT COG0835 Chemotaxis signal transduction protein
PGKGLPEO_03154 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
PGKGLPEO_03155 5.8e-115 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PGKGLPEO_03156 1.2e-144 flhG D Belongs to the ParA family
PGKGLPEO_03157 2.8e-197 flhF N Flagellar biosynthesis regulator FlhF
PGKGLPEO_03158 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PGKGLPEO_03159 1.8e-185 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PGKGLPEO_03160 8.6e-134 fliR N Flagellar biosynthetic protein FliR
PGKGLPEO_03161 1.5e-37 fliQ N Role in flagellar biosynthesis
PGKGLPEO_03162 2.6e-107 fliP N Plays a role in the flagellum-specific transport system
PGKGLPEO_03163 4.6e-115 fliZ N Flagellar biosynthesis protein, FliO
PGKGLPEO_03164 5.5e-59 cheB 3.1.1.61, 3.5.1.44 T response regulator
PGKGLPEO_03165 3.2e-174 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PGKGLPEO_03166 4.9e-182 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PGKGLPEO_03167 1.3e-64 fliL N Controls the rotational direction of flagella during chemotaxis
PGKGLPEO_03168 5e-107 flgG N Flagellar basal body rod
PGKGLPEO_03169 7.9e-71 flg N Putative flagellar
PGKGLPEO_03170 9.6e-107 flgD N Flagellar basal body rod modification protein
PGKGLPEO_03171 1.2e-92 fliK N Flagellar hook-length control
PGKGLPEO_03172 1e-92 ydcK S Belongs to the SprT family
PGKGLPEO_03173 0.0 yhgF K COG2183 Transcriptional accessory protein
PGKGLPEO_03174 8.6e-110 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
PGKGLPEO_03175 1.3e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGKGLPEO_03176 2.3e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PGKGLPEO_03177 3.6e-61 rsbV T Belongs to the anti-sigma-factor antagonist family
PGKGLPEO_03178 6.4e-190 rsbU 3.1.3.3 KT phosphatase
PGKGLPEO_03179 2e-70 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PGKGLPEO_03180 2.1e-55 rsbS T antagonist
PGKGLPEO_03181 3e-153 rsbR T Positive regulator of sigma-B
PGKGLPEO_03182 7.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
PGKGLPEO_03183 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PGKGLPEO_03184 3.7e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGKGLPEO_03185 5.7e-186 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
PGKGLPEO_03186 1.1e-54 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PGKGLPEO_03187 2e-98 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
PGKGLPEO_03188 1.4e-259 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)