ORF_ID e_value Gene_name EC_number CAZy COGs Description
NFHJGHIM_00001 3.9e-73 comF S competence protein
NFHJGHIM_00002 1.1e-107 dprA LU DNA recombination-mediator protein A
NFHJGHIM_00003 2.3e-173 int L Phage integrase, N-terminal SAM-like domain
NFHJGHIM_00004 9.2e-119 K Bacterial regulatory proteins, tetR family
NFHJGHIM_00005 2.5e-215 G Transmembrane secretion effector
NFHJGHIM_00006 2.6e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NFHJGHIM_00007 1.5e-39
NFHJGHIM_00008 3.3e-55
NFHJGHIM_00009 2.6e-43 3.6.1.13 L NUDIX domain
NFHJGHIM_00010 2.9e-226 glf 5.4.99.9 M UDP-galactopyranose mutase
NFHJGHIM_00011 0.0 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
NFHJGHIM_00012 1.9e-170 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
NFHJGHIM_00013 2.8e-106 rgpC U Transport permease protein
NFHJGHIM_00014 7.7e-129 glfT1 1.1.1.133 S Glycosyltransferase, group 2 family protein
NFHJGHIM_00015 1.3e-182 M Glycosyl transferases group 1
NFHJGHIM_00016 1.3e-61 S Polysaccharide pyruvyl transferase
NFHJGHIM_00017 1.1e-13 L Transposase
NFHJGHIM_00018 2e-79 S Acyltransferase family
NFHJGHIM_00019 5.7e-185 S Psort location CytoplasmicMembrane, score
NFHJGHIM_00020 2.2e-168 rfbJ M Glycosyl transferase family 2
NFHJGHIM_00021 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
NFHJGHIM_00022 1.4e-30 I transferase activity, transferring acyl groups other than amino-acyl groups
NFHJGHIM_00023 2.1e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NFHJGHIM_00024 1.3e-75 T protein histidine kinase activity
NFHJGHIM_00025 2.3e-90 K LytTr DNA-binding domain
NFHJGHIM_00026 1e-47 S Protein of unknown function (DUF3073)
NFHJGHIM_00027 1.2e-202 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NFHJGHIM_00028 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NFHJGHIM_00029 1.4e-177 S Amidohydrolase family
NFHJGHIM_00030 0.0 yjjP S Threonine/Serine exporter, ThrE
NFHJGHIM_00031 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NFHJGHIM_00032 0.0 KLT Protein tyrosine kinase
NFHJGHIM_00033 8.4e-151 O Thioredoxin
NFHJGHIM_00035 1.2e-211 S G5
NFHJGHIM_00036 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NFHJGHIM_00037 7.9e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NFHJGHIM_00038 2e-112 S LytR cell envelope-related transcriptional attenuator
NFHJGHIM_00039 1e-278 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
NFHJGHIM_00040 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
NFHJGHIM_00041 0.0 M Conserved repeat domain
NFHJGHIM_00042 0.0 murJ KLT MviN-like protein
NFHJGHIM_00043 9e-204 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NFHJGHIM_00044 2.6e-242 parB K Belongs to the ParB family
NFHJGHIM_00045 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
NFHJGHIM_00046 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NFHJGHIM_00047 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
NFHJGHIM_00048 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
NFHJGHIM_00049 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NFHJGHIM_00050 4.1e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NFHJGHIM_00051 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NFHJGHIM_00052 1.4e-240 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NFHJGHIM_00053 3.2e-93 S Protein of unknown function (DUF721)
NFHJGHIM_00054 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NFHJGHIM_00055 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NFHJGHIM_00056 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
NFHJGHIM_00057 2.6e-15 abfA1 3.2.1.55 GH51 G arabinose metabolic process
NFHJGHIM_00059 7.9e-187 G Glycosyl hydrolases family 43
NFHJGHIM_00060 5.5e-188 K Periplasmic binding protein domain
NFHJGHIM_00061 6.1e-229 I Serine aminopeptidase, S33
NFHJGHIM_00062 6.7e-09 K helix_turn _helix lactose operon repressor
NFHJGHIM_00064 1.9e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NFHJGHIM_00065 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NFHJGHIM_00066 2.5e-124 gntR K FCD
NFHJGHIM_00067 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NFHJGHIM_00068 0.0 3.2.1.55 GH51 G arabinose metabolic process
NFHJGHIM_00071 0.0 G Glycosyl hydrolase family 20, domain 2
NFHJGHIM_00072 4.3e-189 K helix_turn _helix lactose operon repressor
NFHJGHIM_00073 3.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NFHJGHIM_00074 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
NFHJGHIM_00075 1.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
NFHJGHIM_00076 8.2e-134 S Protein of unknown function DUF45
NFHJGHIM_00077 1.9e-83 dps P Belongs to the Dps family
NFHJGHIM_00078 2.9e-188 yddG EG EamA-like transporter family
NFHJGHIM_00079 1e-240 ytfL P Transporter associated domain
NFHJGHIM_00080 4.9e-57 K Cro/C1-type HTH DNA-binding domain
NFHJGHIM_00081 2e-12 E IrrE N-terminal-like domain
NFHJGHIM_00082 3.9e-50 E IrrE N-terminal-like domain
NFHJGHIM_00083 6.8e-65
NFHJGHIM_00084 1.9e-61
NFHJGHIM_00086 6.7e-127 S Domain of unknown function (DUF4417)
NFHJGHIM_00087 1.9e-42 S Bacterial mobilisation protein (MobC)
NFHJGHIM_00088 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NFHJGHIM_00090 1.1e-172 htpX O Belongs to the peptidase M48B family
NFHJGHIM_00091 2.5e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
NFHJGHIM_00092 0.0 cadA P E1-E2 ATPase
NFHJGHIM_00093 7.2e-243 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
NFHJGHIM_00094 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NFHJGHIM_00096 2.2e-87 yjcF Q Acetyltransferase (GNAT) domain
NFHJGHIM_00097 3.1e-158 I Serine aminopeptidase, S33
NFHJGHIM_00098 2.1e-52 ybjQ S Putative heavy-metal-binding
NFHJGHIM_00099 1.8e-34
NFHJGHIM_00100 2.6e-91 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NFHJGHIM_00101 0.0 KL Domain of unknown function (DUF3427)
NFHJGHIM_00103 1e-195 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NFHJGHIM_00105 1.2e-87
NFHJGHIM_00106 4.8e-166 yicL EG EamA-like transporter family
NFHJGHIM_00107 3.9e-206 pldB 3.1.1.5 I Serine aminopeptidase, S33
NFHJGHIM_00108 1.8e-296 pip S YhgE Pip domain protein
NFHJGHIM_00109 0.0 pip S YhgE Pip domain protein
NFHJGHIM_00110 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
NFHJGHIM_00111 1e-130 fhaA T Protein of unknown function (DUF2662)
NFHJGHIM_00112 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
NFHJGHIM_00113 9.7e-260 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
NFHJGHIM_00114 2.8e-266 rodA D Belongs to the SEDS family
NFHJGHIM_00115 3.7e-263 pbpA M penicillin-binding protein
NFHJGHIM_00116 2e-183 T Protein tyrosine kinase
NFHJGHIM_00117 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
NFHJGHIM_00118 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
NFHJGHIM_00119 1.7e-232 srtA 3.4.22.70 M Sortase family
NFHJGHIM_00120 3.5e-143 S Bacterial protein of unknown function (DUF881)
NFHJGHIM_00121 2.6e-71 crgA D Involved in cell division
NFHJGHIM_00122 5.2e-256 L ribosomal rna small subunit methyltransferase
NFHJGHIM_00123 6.7e-120 L HTH-like domain
NFHJGHIM_00124 6.4e-145 gluP 3.4.21.105 S Rhomboid family
NFHJGHIM_00125 3.4e-35
NFHJGHIM_00126 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NFHJGHIM_00127 2e-73 I Sterol carrier protein
NFHJGHIM_00128 6.9e-37 V ATPases associated with a variety of cellular activities
NFHJGHIM_00129 1.1e-43 L Transposase
NFHJGHIM_00130 2.5e-52 L IstB-like ATP binding protein
NFHJGHIM_00131 1.8e-43 tnp7109-21 L Integrase core domain
NFHJGHIM_00132 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
NFHJGHIM_00133 4.5e-12
NFHJGHIM_00134 5e-13 S Putative phage holin Dp-1
NFHJGHIM_00135 2.1e-48 M Glycosyl hydrolases family 25
NFHJGHIM_00136 2.3e-29 M Glycosyl hydrolases family 25
NFHJGHIM_00138 1.7e-17 S Protein of unknown function (DUF2806)
NFHJGHIM_00140 3.5e-57 L Transposase and inactivated derivatives IS30 family
NFHJGHIM_00141 3e-113 K WHG domain
NFHJGHIM_00142 1.4e-90 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
NFHJGHIM_00143 1.4e-13
NFHJGHIM_00144 5.6e-272
NFHJGHIM_00145 7.6e-299 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
NFHJGHIM_00147 6.5e-229 3.1.21.3 V Type I restriction modification DNA specificity domain
NFHJGHIM_00148 2e-180 V Abi-like protein
NFHJGHIM_00149 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NFHJGHIM_00150 1.4e-59 S Bacterial mobilisation protein (MobC)
NFHJGHIM_00151 0.0 ltrBE1 U Relaxase/Mobilisation nuclease domain
NFHJGHIM_00152 4.7e-105
NFHJGHIM_00153 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
NFHJGHIM_00154 3.2e-155 S Domain of unknown function (DUF4357)
NFHJGHIM_00155 2.1e-88 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
NFHJGHIM_00156 1e-178 L Phage integrase family
NFHJGHIM_00157 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NFHJGHIM_00158 1.4e-84 argR K Regulates arginine biosynthesis genes
NFHJGHIM_00159 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NFHJGHIM_00160 2.5e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
NFHJGHIM_00161 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NFHJGHIM_00162 3e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NFHJGHIM_00163 7.2e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NFHJGHIM_00164 5.1e-87
NFHJGHIM_00165 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
NFHJGHIM_00166 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NFHJGHIM_00167 1.3e-159 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NFHJGHIM_00168 6.9e-136 ybbL V ATPases associated with a variety of cellular activities
NFHJGHIM_00169 4.2e-136 ybbM V Uncharacterised protein family (UPF0014)
NFHJGHIM_00170 4.3e-46 IQ oxidoreductase activity
NFHJGHIM_00172 1e-104 K AraC-like ligand binding domain
NFHJGHIM_00173 2.4e-237 rutG F Permease family
NFHJGHIM_00174 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
NFHJGHIM_00175 5.7e-55 estB S Phospholipase/Carboxylesterase
NFHJGHIM_00176 2.7e-186 MA20_14895 S Conserved hypothetical protein 698
NFHJGHIM_00177 2.3e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
NFHJGHIM_00178 2.9e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
NFHJGHIM_00179 3.2e-289 2.4.1.166 GT2 M Glycosyltransferase like family 2
NFHJGHIM_00181 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
NFHJGHIM_00182 1.2e-125 ypfH S Phospholipase/Carboxylesterase
NFHJGHIM_00183 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NFHJGHIM_00184 2.1e-23
NFHJGHIM_00185 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NFHJGHIM_00186 1.1e-65 S Zincin-like metallopeptidase
NFHJGHIM_00187 6.6e-86 S Helix-turn-helix
NFHJGHIM_00188 2.5e-199 S Short C-terminal domain
NFHJGHIM_00189 2.7e-22
NFHJGHIM_00190 4.1e-149
NFHJGHIM_00191 4.5e-79 K Psort location Cytoplasmic, score
NFHJGHIM_00192 5.9e-257 KLT Protein tyrosine kinase
NFHJGHIM_00193 2.1e-66 S Cupin 2, conserved barrel domain protein
NFHJGHIM_00194 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
NFHJGHIM_00195 5.6e-59 yccF S Inner membrane component domain
NFHJGHIM_00196 8.6e-120 E Psort location Cytoplasmic, score 8.87
NFHJGHIM_00197 9.5e-239 yhjX EGP Major facilitator Superfamily
NFHJGHIM_00198 1.3e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NFHJGHIM_00199 1.1e-95 K helix_turn _helix lactose operon repressor
NFHJGHIM_00200 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NFHJGHIM_00201 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
NFHJGHIM_00202 0.0 trxB1 1.8.1.9 C Thioredoxin domain
NFHJGHIM_00206 2.8e-156 S PAC2 family
NFHJGHIM_00207 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NFHJGHIM_00208 7.1e-160 G Fructosamine kinase
NFHJGHIM_00209 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NFHJGHIM_00210 3.9e-213 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NFHJGHIM_00211 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
NFHJGHIM_00212 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NFHJGHIM_00213 1.2e-143 yoaK S Protein of unknown function (DUF1275)
NFHJGHIM_00214 4.4e-253 brnQ U Component of the transport system for branched-chain amino acids
NFHJGHIM_00216 3.1e-243 mepA_6 V MatE
NFHJGHIM_00217 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
NFHJGHIM_00218 3.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NFHJGHIM_00219 8e-33 secG U Preprotein translocase SecG subunit
NFHJGHIM_00220 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NFHJGHIM_00221 7.6e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
NFHJGHIM_00222 3.1e-173 whiA K May be required for sporulation
NFHJGHIM_00223 1.3e-176 rapZ S Displays ATPase and GTPase activities
NFHJGHIM_00224 7.5e-180 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
NFHJGHIM_00225 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NFHJGHIM_00226 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NFHJGHIM_00227 1.4e-76
NFHJGHIM_00228 9.3e-28 V MacB-like periplasmic core domain
NFHJGHIM_00229 8.2e-117 K Transcriptional regulatory protein, C terminal
NFHJGHIM_00230 1.1e-240 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NFHJGHIM_00231 2.2e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NFHJGHIM_00232 8.9e-303 ybiT S ABC transporter
NFHJGHIM_00233 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NFHJGHIM_00234 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NFHJGHIM_00235 4.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
NFHJGHIM_00236 6.4e-218 GK ROK family
NFHJGHIM_00237 1.5e-177 2.7.1.2 GK ROK family
NFHJGHIM_00238 1.2e-287 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
NFHJGHIM_00239 4.4e-307 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
NFHJGHIM_00240 2.2e-256 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
NFHJGHIM_00241 2.2e-165
NFHJGHIM_00242 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
NFHJGHIM_00243 8.3e-164 L Helix-turn-helix domain
NFHJGHIM_00244 1.1e-10
NFHJGHIM_00245 2e-94
NFHJGHIM_00246 5.2e-132 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
NFHJGHIM_00249 1.2e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NFHJGHIM_00250 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
NFHJGHIM_00251 8.5e-273 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NFHJGHIM_00252 3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NFHJGHIM_00253 1.9e-203 S Endonuclease/Exonuclease/phosphatase family
NFHJGHIM_00255 5.3e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NFHJGHIM_00256 5e-254 cdr OP Sulfurtransferase TusA
NFHJGHIM_00257 2.6e-149 moeB 2.7.7.80 H ThiF family
NFHJGHIM_00258 1.6e-132 tmp1 S Domain of unknown function (DUF4391)
NFHJGHIM_00259 4e-37 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
NFHJGHIM_00260 3.7e-229 aspB E Aminotransferase class-V
NFHJGHIM_00261 2.2e-125 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NFHJGHIM_00262 1.4e-270 S zinc finger
NFHJGHIM_00263 2.6e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NFHJGHIM_00264 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NFHJGHIM_00265 3.1e-250 O Subtilase family
NFHJGHIM_00266 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
NFHJGHIM_00267 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NFHJGHIM_00268 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NFHJGHIM_00269 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NFHJGHIM_00270 1.8e-56 L Transposase
NFHJGHIM_00271 6.4e-24 relB L RelB antitoxin
NFHJGHIM_00272 2.3e-18 appF P Belongs to the ABC transporter superfamily
NFHJGHIM_00273 4.9e-249 G Major Facilitator Superfamily
NFHJGHIM_00274 8.6e-159 K -acetyltransferase
NFHJGHIM_00275 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
NFHJGHIM_00276 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
NFHJGHIM_00277 9.8e-269 KLT Protein tyrosine kinase
NFHJGHIM_00278 0.0 S Fibronectin type 3 domain
NFHJGHIM_00279 5.7e-231 S ATPase family associated with various cellular activities (AAA)
NFHJGHIM_00280 1.8e-232 S Protein of unknown function DUF58
NFHJGHIM_00281 0.0 E Transglutaminase-like superfamily
NFHJGHIM_00282 1.3e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
NFHJGHIM_00283 1.1e-67 B Belongs to the OprB family
NFHJGHIM_00284 3.8e-96 T Forkhead associated domain
NFHJGHIM_00285 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFHJGHIM_00286 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFHJGHIM_00287 9.6e-102
NFHJGHIM_00288 2.1e-182 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
NFHJGHIM_00289 3.5e-34 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G xyloglucan:xyloglucosyl transferase activity
NFHJGHIM_00290 5.9e-52 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
NFHJGHIM_00291 1.5e-07 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
NFHJGHIM_00292 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NFHJGHIM_00293 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
NFHJGHIM_00294 8e-102 L Helix-turn-helix domain
NFHJGHIM_00295 0.0 S LPXTG-motif cell wall anchor domain protein
NFHJGHIM_00296 3.5e-222 M LPXTG-motif cell wall anchor domain protein
NFHJGHIM_00297 2.8e-180 3.4.22.70 M Sortase family
NFHJGHIM_00298 3.7e-154
NFHJGHIM_00299 1e-270 KLT Domain of unknown function (DUF4032)
NFHJGHIM_00300 4.9e-174 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NFHJGHIM_00302 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
NFHJGHIM_00303 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
NFHJGHIM_00304 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
NFHJGHIM_00305 0.0 yjcE P Sodium/hydrogen exchanger family
NFHJGHIM_00306 1.2e-145 ypfH S Phospholipase/Carboxylesterase
NFHJGHIM_00307 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NFHJGHIM_00308 2.2e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
NFHJGHIM_00309 3e-144 cobB2 K Sir2 family
NFHJGHIM_00312 2e-19
NFHJGHIM_00314 0.0 traA 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NFHJGHIM_00318 3.1e-71 K Transcriptional regulator
NFHJGHIM_00322 4e-220 U TraM recognition site of TraD and TraG
NFHJGHIM_00323 4.8e-171 U Type IV secretory pathway, VirB4
NFHJGHIM_00325 0.0 sprF 4.6.1.1 M Cell surface antigen C-terminus
NFHJGHIM_00326 3.3e-12
NFHJGHIM_00328 5.6e-118
NFHJGHIM_00329 2.1e-43
NFHJGHIM_00332 3.3e-142 mltE2 M Bacteriophage peptidoglycan hydrolase
NFHJGHIM_00333 9.6e-123 L Phage integrase family
NFHJGHIM_00334 9.2e-120 pdtaR T Response regulator receiver domain protein
NFHJGHIM_00335 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NFHJGHIM_00336 1.4e-170 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
NFHJGHIM_00337 1.1e-119 3.6.1.13 L NUDIX domain
NFHJGHIM_00338 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NFHJGHIM_00339 1.4e-219 ykiI
NFHJGHIM_00341 4.2e-135 L Phage integrase family
NFHJGHIM_00342 2.9e-108 3.4.13.21 E Peptidase family S51
NFHJGHIM_00343 2.7e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NFHJGHIM_00344 1.3e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NFHJGHIM_00345 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NFHJGHIM_00346 6.8e-71 XK27_07020 S Domain of unknown function (DUF1846)
NFHJGHIM_00347 2.2e-80
NFHJGHIM_00348 4.2e-09 S Domain of unknown function (DUF4339)
NFHJGHIM_00349 8.7e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NFHJGHIM_00350 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NFHJGHIM_00351 4.4e-189 pit P Phosphate transporter family
NFHJGHIM_00352 1.1e-115 MA20_27875 P Protein of unknown function DUF47
NFHJGHIM_00353 6.9e-119 K helix_turn_helix, Lux Regulon
NFHJGHIM_00354 1.9e-115 T Histidine kinase
NFHJGHIM_00355 6e-93 T Histidine kinase
NFHJGHIM_00356 3.4e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NFHJGHIM_00357 4.1e-181 V ATPases associated with a variety of cellular activities
NFHJGHIM_00358 8.1e-227 V ABC-2 family transporter protein
NFHJGHIM_00359 5.8e-253 V ABC-2 family transporter protein
NFHJGHIM_00360 5.9e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NFHJGHIM_00361 5.7e-180 L Transposase and inactivated derivatives IS30 family
NFHJGHIM_00363 3.9e-78
NFHJGHIM_00364 1.3e-63 D MobA/MobL family
NFHJGHIM_00365 8.1e-46 L Transposase
NFHJGHIM_00366 5.8e-169 tnp7109-21 L Integrase core domain
NFHJGHIM_00367 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
NFHJGHIM_00368 2.4e-40
NFHJGHIM_00369 5.6e-112 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
NFHJGHIM_00371 5.6e-37 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NFHJGHIM_00373 4.1e-240 pbuX F Permease family
NFHJGHIM_00374 1.9e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NFHJGHIM_00375 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
NFHJGHIM_00376 0.0 pcrA 3.6.4.12 L DNA helicase
NFHJGHIM_00377 8.2e-64 S Domain of unknown function (DUF4418)
NFHJGHIM_00378 3.2e-212 V FtsX-like permease family
NFHJGHIM_00379 1.9e-128 lolD V ABC transporter
NFHJGHIM_00380 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NFHJGHIM_00381 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
NFHJGHIM_00382 5.1e-42 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
NFHJGHIM_00383 1.1e-90 K MarR family
NFHJGHIM_00384 0.0 V ABC transporter, ATP-binding protein
NFHJGHIM_00385 0.0 V ABC transporter transmembrane region
NFHJGHIM_00386 1.2e-167 S Patatin-like phospholipase
NFHJGHIM_00387 1.5e-152 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NFHJGHIM_00388 1.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NFHJGHIM_00389 2e-115 S Vitamin K epoxide reductase
NFHJGHIM_00390 5.6e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
NFHJGHIM_00391 6.1e-32 S Protein of unknown function (DUF3107)
NFHJGHIM_00392 1.2e-245 mphA S Aminoglycoside phosphotransferase
NFHJGHIM_00393 6.2e-282 uvrD2 3.6.4.12 L DNA helicase
NFHJGHIM_00394 1.2e-288 S Zincin-like metallopeptidase
NFHJGHIM_00395 7.6e-152 lon T Belongs to the peptidase S16 family
NFHJGHIM_00396 5.7e-47 S Protein of unknown function (DUF3052)
NFHJGHIM_00397 5.2e-195 K helix_turn _helix lactose operon repressor
NFHJGHIM_00398 4e-60 S Thiamine-binding protein
NFHJGHIM_00399 2.7e-163 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NFHJGHIM_00400 6.9e-231 O AAA domain (Cdc48 subfamily)
NFHJGHIM_00401 1.3e-84
NFHJGHIM_00402 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NFHJGHIM_00403 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NFHJGHIM_00404 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
NFHJGHIM_00405 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
NFHJGHIM_00406 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NFHJGHIM_00407 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NFHJGHIM_00408 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NFHJGHIM_00409 2.1e-42 yggT S YGGT family
NFHJGHIM_00410 9.7e-90 3.1.21.3 V DivIVA protein
NFHJGHIM_00411 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NFHJGHIM_00412 3.4e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NFHJGHIM_00414 7.8e-63
NFHJGHIM_00415 2.6e-138 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NFHJGHIM_00416 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NFHJGHIM_00417 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
NFHJGHIM_00418 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
NFHJGHIM_00419 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
NFHJGHIM_00420 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NFHJGHIM_00421 9.6e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
NFHJGHIM_00422 1.5e-45
NFHJGHIM_00423 3.6e-23
NFHJGHIM_00424 4.7e-14
NFHJGHIM_00425 1.4e-12 L PFAM Integrase catalytic
NFHJGHIM_00427 9.7e-201 2.7.11.1 NU Tfp pilus assembly protein FimV
NFHJGHIM_00428 5.2e-223 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NFHJGHIM_00429 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NFHJGHIM_00430 5e-293 I acetylesterase activity
NFHJGHIM_00431 7e-144 recO L Involved in DNA repair and RecF pathway recombination
NFHJGHIM_00432 1.8e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NFHJGHIM_00433 4.3e-191 ywqG S Domain of unknown function (DUF1963)
NFHJGHIM_00434 6e-46 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
NFHJGHIM_00435 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
NFHJGHIM_00436 2.2e-105 S zinc-ribbon domain
NFHJGHIM_00437 1.6e-46 yhbY J CRS1_YhbY
NFHJGHIM_00438 0.0 4.2.1.53 S MCRA family
NFHJGHIM_00440 3.4e-202 K WYL domain
NFHJGHIM_00441 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
NFHJGHIM_00442 1.3e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
NFHJGHIM_00443 4.9e-75 yneG S Domain of unknown function (DUF4186)
NFHJGHIM_00445 5.6e-183 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NFHJGHIM_00446 7.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NFHJGHIM_00447 7.9e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NFHJGHIM_00448 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
NFHJGHIM_00449 5e-112
NFHJGHIM_00450 1.1e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NFHJGHIM_00451 4.1e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
NFHJGHIM_00452 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
NFHJGHIM_00453 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
NFHJGHIM_00454 2.7e-252 S Domain of unknown function (DUF5067)
NFHJGHIM_00455 2.1e-61 EGP Major facilitator Superfamily
NFHJGHIM_00456 2.2e-177 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NFHJGHIM_00457 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
NFHJGHIM_00458 7e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
NFHJGHIM_00459 1.4e-170
NFHJGHIM_00460 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NFHJGHIM_00461 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
NFHJGHIM_00462 6e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NFHJGHIM_00463 6.3e-128 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NFHJGHIM_00464 6.1e-45 M Lysin motif
NFHJGHIM_00465 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NFHJGHIM_00466 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NFHJGHIM_00467 0.0 L DNA helicase
NFHJGHIM_00468 1.3e-90 mraZ K Belongs to the MraZ family
NFHJGHIM_00469 1.6e-205 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NFHJGHIM_00470 2.3e-23 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NFHJGHIM_00471 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
NFHJGHIM_00472 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NFHJGHIM_00473 7.6e-283 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NFHJGHIM_00474 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NFHJGHIM_00475 3.5e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NFHJGHIM_00476 1.2e-223 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
NFHJGHIM_00477 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NFHJGHIM_00478 6.8e-295 murC 6.3.2.8 M Belongs to the MurCDEF family
NFHJGHIM_00479 1.8e-157 ftsQ 6.3.2.4 D Cell division protein FtsQ
NFHJGHIM_00480 4.9e-37
NFHJGHIM_00482 1.2e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NFHJGHIM_00483 4.4e-236 G Major Facilitator Superfamily
NFHJGHIM_00484 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
NFHJGHIM_00485 1.5e-222 GK ROK family
NFHJGHIM_00486 3.8e-131 cutC P Participates in the control of copper homeostasis
NFHJGHIM_00487 1e-215 GK ROK family
NFHJGHIM_00488 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NFHJGHIM_00489 7.4e-244 nagA 3.5.1.25 G Amidohydrolase family
NFHJGHIM_00490 3.3e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
NFHJGHIM_00491 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
NFHJGHIM_00492 5.1e-191 dppC EP Binding-protein-dependent transport system inner membrane component
NFHJGHIM_00493 0.0 P Belongs to the ABC transporter superfamily
NFHJGHIM_00494 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
NFHJGHIM_00495 9.6e-97 3.6.1.55 F NUDIX domain
NFHJGHIM_00497 9.5e-284 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
NFHJGHIM_00498 0.0 smc D Required for chromosome condensation and partitioning
NFHJGHIM_00499 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
NFHJGHIM_00500 4e-242 yxbA 6.3.1.12 S ATP-grasp
NFHJGHIM_00501 2.4e-228 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
NFHJGHIM_00502 5.2e-192 V Acetyltransferase (GNAT) domain
NFHJGHIM_00503 1.3e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NFHJGHIM_00504 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
NFHJGHIM_00505 2e-64
NFHJGHIM_00506 4.5e-193 galM 5.1.3.3 G Aldose 1-epimerase
NFHJGHIM_00507 5.5e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NFHJGHIM_00508 6.3e-101 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NFHJGHIM_00509 3.6e-199 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NFHJGHIM_00510 8.3e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
NFHJGHIM_00511 7.1e-68 S Spermine/spermidine synthase domain
NFHJGHIM_00512 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NFHJGHIM_00513 2.1e-25 rpmI J Ribosomal protein L35
NFHJGHIM_00514 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NFHJGHIM_00515 7.6e-180 xerD D recombinase XerD
NFHJGHIM_00516 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
NFHJGHIM_00517 1.4e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NFHJGHIM_00518 2.5e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NFHJGHIM_00519 1.6e-148 nrtR 3.6.1.55 F NUDIX hydrolase
NFHJGHIM_00520 7.5e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NFHJGHIM_00521 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NFHJGHIM_00522 9.1e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
NFHJGHIM_00523 6.8e-237 iscS1 2.8.1.7 E Aminotransferase class-V
NFHJGHIM_00524 0.0 typA T Elongation factor G C-terminus
NFHJGHIM_00525 1.7e-80
NFHJGHIM_00526 2.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
NFHJGHIM_00527 4.9e-193 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
NFHJGHIM_00528 7.3e-42
NFHJGHIM_00529 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NFHJGHIM_00530 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
NFHJGHIM_00531 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
NFHJGHIM_00532 0.0 oppD P Belongs to the ABC transporter superfamily
NFHJGHIM_00533 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
NFHJGHIM_00534 6.8e-262 pepC 3.4.22.40 E Peptidase C1-like family
NFHJGHIM_00535 1.4e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
NFHJGHIM_00536 2.1e-138 S Protein of unknown function (DUF3710)
NFHJGHIM_00537 8.3e-129 S Protein of unknown function (DUF3159)
NFHJGHIM_00538 2.2e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NFHJGHIM_00539 5.8e-109
NFHJGHIM_00540 0.0 ctpE P E1-E2 ATPase
NFHJGHIM_00541 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NFHJGHIM_00543 3e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NFHJGHIM_00544 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
NFHJGHIM_00545 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NFHJGHIM_00546 4.2e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NFHJGHIM_00547 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NFHJGHIM_00548 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NFHJGHIM_00549 1.3e-182 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NFHJGHIM_00550 4.7e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
NFHJGHIM_00551 0.0 arc O AAA ATPase forming ring-shaped complexes
NFHJGHIM_00552 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
NFHJGHIM_00553 1.2e-157 hisN 3.1.3.25 G Inositol monophosphatase family
NFHJGHIM_00554 1.6e-10 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NFHJGHIM_00555 9e-278 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NFHJGHIM_00556 8.1e-42 hup L Belongs to the bacterial histone-like protein family
NFHJGHIM_00557 0.0 S Lysylphosphatidylglycerol synthase TM region
NFHJGHIM_00558 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
NFHJGHIM_00559 1.4e-289 S PGAP1-like protein
NFHJGHIM_00561 3.6e-74
NFHJGHIM_00562 1.1e-147 S von Willebrand factor (vWF) type A domain
NFHJGHIM_00563 2.3e-190 S von Willebrand factor (vWF) type A domain
NFHJGHIM_00564 6.4e-94
NFHJGHIM_00565 7.2e-178 S Protein of unknown function DUF58
NFHJGHIM_00566 1e-196 moxR S ATPase family associated with various cellular activities (AAA)
NFHJGHIM_00567 5.2e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NFHJGHIM_00568 4.9e-70 S LytR cell envelope-related transcriptional attenuator
NFHJGHIM_00569 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
NFHJGHIM_00570 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NFHJGHIM_00571 1.7e-10 S Proteins of 100 residues with WXG
NFHJGHIM_00572 6.2e-173
NFHJGHIM_00573 1.4e-133 KT Response regulator receiver domain protein
NFHJGHIM_00574 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NFHJGHIM_00575 1e-66 cspB K 'Cold-shock' DNA-binding domain
NFHJGHIM_00576 1.1e-192 S Protein of unknown function (DUF3027)
NFHJGHIM_00577 4.7e-185 uspA T Belongs to the universal stress protein A family
NFHJGHIM_00578 0.0 clpC O ATPase family associated with various cellular activities (AAA)
NFHJGHIM_00582 6.6e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
NFHJGHIM_00583 2.7e-263 hisS 6.1.1.21 J Histidyl-tRNA synthetase
NFHJGHIM_00584 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NFHJGHIM_00585 1e-82 K helix_turn_helix, Lux Regulon
NFHJGHIM_00586 8.2e-93 S Aminoacyl-tRNA editing domain
NFHJGHIM_00587 3.6e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
NFHJGHIM_00588 9.5e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
NFHJGHIM_00589 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
NFHJGHIM_00590 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
NFHJGHIM_00591 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
NFHJGHIM_00592 0.0 L DEAD DEAH box helicase
NFHJGHIM_00593 8.5e-257 rarA L Recombination factor protein RarA
NFHJGHIM_00595 4.4e-256 EGP Major facilitator Superfamily
NFHJGHIM_00596 0.0 ecfA GP ABC transporter, ATP-binding protein
NFHJGHIM_00597 9.6e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NFHJGHIM_00599 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
NFHJGHIM_00600 7.8e-213 E Aminotransferase class I and II
NFHJGHIM_00601 3.4e-138 bioM P ATPases associated with a variety of cellular activities
NFHJGHIM_00602 1.1e-71 2.8.2.22 S Arylsulfotransferase Ig-like domain
NFHJGHIM_00603 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NFHJGHIM_00604 0.0 S Tetratricopeptide repeat
NFHJGHIM_00605 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NFHJGHIM_00606 5.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NFHJGHIM_00607 8.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NFHJGHIM_00608 1.5e-86 int L Phage integrase, N-terminal SAM-like domain
NFHJGHIM_00609 4.8e-115 L DNA restriction-modification system
NFHJGHIM_00610 7.8e-33 3.1.21.4 L Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
NFHJGHIM_00611 5.2e-79 S GIY-YIG catalytic domain
NFHJGHIM_00615 5.5e-33 traSA D DNA segregation ATPase FtsK SpoIIIE
NFHJGHIM_00617 4.7e-10
NFHJGHIM_00618 6.9e-286 glnA 6.3.1.2 E glutamine synthetase
NFHJGHIM_00619 2.3e-142 S Domain of unknown function (DUF4191)
NFHJGHIM_00620 9.9e-280 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NFHJGHIM_00621 2.7e-103 S Protein of unknown function (DUF3043)
NFHJGHIM_00622 1.2e-258 argE E Peptidase dimerisation domain
NFHJGHIM_00623 1.3e-191 V N-Acetylmuramoyl-L-alanine amidase
NFHJGHIM_00624 2.6e-149 ytrE V ATPases associated with a variety of cellular activities
NFHJGHIM_00625 2.7e-194
NFHJGHIM_00626 8.1e-230 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
NFHJGHIM_00627 0.0 S Uncharacterised protein family (UPF0182)
NFHJGHIM_00628 1.8e-206 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NFHJGHIM_00629 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NFHJGHIM_00630 8.6e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
NFHJGHIM_00632 1.2e-129 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NFHJGHIM_00633 1.9e-197 GM GDP-mannose 4,6 dehydratase
NFHJGHIM_00634 1.4e-150 GM ABC-2 type transporter
NFHJGHIM_00635 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
NFHJGHIM_00636 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
NFHJGHIM_00637 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NFHJGHIM_00638 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NFHJGHIM_00639 6.1e-301 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
NFHJGHIM_00640 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
NFHJGHIM_00641 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NFHJGHIM_00642 2.5e-101 divIC D Septum formation initiator
NFHJGHIM_00643 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
NFHJGHIM_00644 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
NFHJGHIM_00646 4.7e-97
NFHJGHIM_00647 1.4e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
NFHJGHIM_00648 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
NFHJGHIM_00649 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NFHJGHIM_00651 1.6e-108
NFHJGHIM_00652 5.7e-142 yplQ S Haemolysin-III related
NFHJGHIM_00653 9.5e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NFHJGHIM_00654 4.1e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NFHJGHIM_00655 0.0 D FtsK/SpoIIIE family
NFHJGHIM_00656 2.4e-270 K Cell envelope-related transcriptional attenuator domain
NFHJGHIM_00657 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NFHJGHIM_00658 0.0 S Glycosyl transferase, family 2
NFHJGHIM_00659 2.2e-266
NFHJGHIM_00660 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
NFHJGHIM_00661 5e-156 cof 5.2.1.8 T Eukaryotic phosphomannomutase
NFHJGHIM_00662 7.8e-129 ctsW S Phosphoribosyl transferase domain
NFHJGHIM_00663 1.4e-71 rulA 3.4.21.88 KT Peptidase S24-like
NFHJGHIM_00664 1.9e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NFHJGHIM_00665 1.9e-127 T Response regulator receiver domain protein
NFHJGHIM_00666 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NFHJGHIM_00667 5.1e-102 carD K CarD-like/TRCF domain
NFHJGHIM_00668 1.9e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NFHJGHIM_00669 4.3e-139 znuB U ABC 3 transport family
NFHJGHIM_00670 2.8e-165 znuC P ATPases associated with a variety of cellular activities
NFHJGHIM_00671 2.5e-173 P Zinc-uptake complex component A periplasmic
NFHJGHIM_00672 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NFHJGHIM_00673 3.3e-243 rpsA J Ribosomal protein S1
NFHJGHIM_00674 4.5e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NFHJGHIM_00675 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NFHJGHIM_00676 1.7e-179 terC P Integral membrane protein, TerC family
NFHJGHIM_00677 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
NFHJGHIM_00678 1.8e-110 aspA 3.6.1.13 L NUDIX domain
NFHJGHIM_00682 1e-08 ycf55 KT response regulator
NFHJGHIM_00683 4.6e-37 ydhQ 2.7.11.1 MU cell adhesion
NFHJGHIM_00690 7.7e-10
NFHJGHIM_00692 2.5e-36 higB S RelE-like toxin of type II toxin-antitoxin system HigB
NFHJGHIM_00693 1.1e-31 higA K Helix-turn-helix
NFHJGHIM_00694 3e-158 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
NFHJGHIM_00695 1.5e-233 patB 4.4.1.8 E Aminotransferase, class I II
NFHJGHIM_00698 5.9e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NFHJGHIM_00699 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NFHJGHIM_00700 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NFHJGHIM_00701 5.1e-254 clcA_2 P Voltage gated chloride channel
NFHJGHIM_00702 2.4e-235 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NFHJGHIM_00703 3.5e-249 rnd 3.1.13.5 J 3'-5' exonuclease
NFHJGHIM_00704 1.3e-113 S Protein of unknown function (DUF3000)
NFHJGHIM_00705 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NFHJGHIM_00706 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NFHJGHIM_00707 6.4e-40
NFHJGHIM_00708 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NFHJGHIM_00709 7e-225 S Peptidase dimerisation domain
NFHJGHIM_00710 1.3e-91 P ABC-type metal ion transport system permease component
NFHJGHIM_00711 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
NFHJGHIM_00712 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NFHJGHIM_00713 1.1e-49 relB L RelB antitoxin
NFHJGHIM_00714 1.1e-39 T Toxic component of a toxin-antitoxin (TA) module
NFHJGHIM_00715 1.3e-207 E Belongs to the peptidase S1B family
NFHJGHIM_00716 1.4e-12
NFHJGHIM_00717 2.7e-28
NFHJGHIM_00718 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NFHJGHIM_00719 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NFHJGHIM_00720 1.4e-47 S Domain of unknown function (DUF4193)
NFHJGHIM_00721 1.1e-187 S Protein of unknown function (DUF3071)
NFHJGHIM_00722 1.3e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
NFHJGHIM_00723 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
NFHJGHIM_00724 0.0 lhr L DEAD DEAH box helicase
NFHJGHIM_00725 1.2e-36 K Transcriptional regulator
NFHJGHIM_00726 4.4e-277 aspA 4.3.1.1 E Fumarase C C-terminus
NFHJGHIM_00727 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
NFHJGHIM_00728 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NFHJGHIM_00729 5e-122
NFHJGHIM_00730 1.5e-200 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
NFHJGHIM_00731 0.0 pknL 2.7.11.1 KLT PASTA
NFHJGHIM_00732 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
NFHJGHIM_00733 1.5e-109
NFHJGHIM_00734 5.4e-192 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NFHJGHIM_00735 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NFHJGHIM_00736 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NFHJGHIM_00738 1e-07
NFHJGHIM_00739 2.9e-87 recX S Modulates RecA activity
NFHJGHIM_00740 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NFHJGHIM_00741 8.2e-40 S Protein of unknown function (DUF3046)
NFHJGHIM_00742 1.6e-80 K Helix-turn-helix XRE-family like proteins
NFHJGHIM_00743 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
NFHJGHIM_00744 3.2e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NFHJGHIM_00745 0.0 ftsK D FtsK SpoIIIE family protein
NFHJGHIM_00746 1.2e-137 fic D Fic/DOC family
NFHJGHIM_00747 4e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NFHJGHIM_00748 1.3e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NFHJGHIM_00749 7.1e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
NFHJGHIM_00750 2.9e-171 ydeD EG EamA-like transporter family
NFHJGHIM_00751 6.6e-132 ybhL S Belongs to the BI1 family
NFHJGHIM_00752 2.8e-95 S Domain of unknown function (DUF5067)
NFHJGHIM_00753 8.4e-268 T Histidine kinase
NFHJGHIM_00754 1.1e-116 K helix_turn_helix, Lux Regulon
NFHJGHIM_00755 0.0 S Protein of unknown function DUF262
NFHJGHIM_00756 4.4e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NFHJGHIM_00757 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NFHJGHIM_00758 6.9e-239 carA 6.3.5.5 F Belongs to the CarA family
NFHJGHIM_00759 6.1e-88 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NFHJGHIM_00760 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NFHJGHIM_00762 9.5e-190 EGP Transmembrane secretion effector
NFHJGHIM_00763 6e-146 S Esterase-like activity of phytase
NFHJGHIM_00764 4.9e-174 S Esterase-like activity of phytase
NFHJGHIM_00765 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NFHJGHIM_00766 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NFHJGHIM_00767 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NFHJGHIM_00768 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NFHJGHIM_00770 5.9e-199 ltaE 4.1.2.48 E Beta-eliminating lyase
NFHJGHIM_00771 1e-226 M Glycosyl transferase 4-like domain
NFHJGHIM_00772 0.0 M Parallel beta-helix repeats
NFHJGHIM_00773 8.3e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NFHJGHIM_00774 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NFHJGHIM_00775 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
NFHJGHIM_00776 1.3e-109
NFHJGHIM_00777 9e-97 S Protein of unknown function (DUF4230)
NFHJGHIM_00778 4.3e-152 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
NFHJGHIM_00779 8.9e-33 K DNA-binding transcription factor activity
NFHJGHIM_00780 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFHJGHIM_00781 2e-32
NFHJGHIM_00782 2.3e-303 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
NFHJGHIM_00783 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NFHJGHIM_00784 6.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NFHJGHIM_00785 5e-240 purD 6.3.4.13 F Belongs to the GARS family
NFHJGHIM_00786 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
NFHJGHIM_00787 6e-247 S Putative esterase
NFHJGHIM_00788 0.0 lysX S Uncharacterised conserved protein (DUF2156)
NFHJGHIM_00789 5.6e-161 P Zinc-uptake complex component A periplasmic
NFHJGHIM_00790 4.8e-137 S cobalamin synthesis protein
NFHJGHIM_00791 8.8e-47 rpmB J Ribosomal L28 family
NFHJGHIM_00792 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NFHJGHIM_00793 6.3e-41 rpmE2 J Ribosomal protein L31
NFHJGHIM_00794 8.2e-15 rpmJ J Ribosomal protein L36
NFHJGHIM_00795 2.3e-23 J Ribosomal L32p protein family
NFHJGHIM_00796 2.6e-200 ycgR S Predicted permease
NFHJGHIM_00797 7.7e-154 S TIGRFAM TIGR03943 family protein
NFHJGHIM_00798 1.1e-43
NFHJGHIM_00799 4.3e-73 zur P Belongs to the Fur family
NFHJGHIM_00800 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NFHJGHIM_00801 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NFHJGHIM_00802 4.5e-180 adh3 C Zinc-binding dehydrogenase
NFHJGHIM_00803 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NFHJGHIM_00805 1.4e-44 S Memo-like protein
NFHJGHIM_00806 5.8e-230 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NFHJGHIM_00807 1e-159 K Helix-turn-helix domain, rpiR family
NFHJGHIM_00808 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NFHJGHIM_00809 2.9e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
NFHJGHIM_00810 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NFHJGHIM_00811 4.4e-269 yhdG E aromatic amino acid transport protein AroP K03293
NFHJGHIM_00812 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NFHJGHIM_00813 2.1e-31 J Acetyltransferase (GNAT) domain
NFHJGHIM_00814 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NFHJGHIM_00815 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NFHJGHIM_00816 1.6e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NFHJGHIM_00817 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
NFHJGHIM_00818 4.4e-109
NFHJGHIM_00819 1.7e-34 L Psort location Cytoplasmic, score 8.87
NFHJGHIM_00820 9.9e-125 3.5.1.28 M NLP P60 protein
NFHJGHIM_00821 1.9e-66 S SPP1 phage holin
NFHJGHIM_00822 1.3e-69
NFHJGHIM_00823 2.3e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
NFHJGHIM_00824 1.1e-45
NFHJGHIM_00825 2.6e-30 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
NFHJGHIM_00826 4.6e-188 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NFHJGHIM_00827 2.5e-150 sapF E ATPases associated with a variety of cellular activities
NFHJGHIM_00828 5.7e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
NFHJGHIM_00829 4.6e-161 EP Binding-protein-dependent transport system inner membrane component
NFHJGHIM_00830 7.2e-170 P Binding-protein-dependent transport system inner membrane component
NFHJGHIM_00831 1.8e-309 E ABC transporter, substrate-binding protein, family 5
NFHJGHIM_00832 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NFHJGHIM_00833 2.6e-277 G Bacterial extracellular solute-binding protein
NFHJGHIM_00834 1.1e-63 G carbohydrate transport
NFHJGHIM_00835 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NFHJGHIM_00836 5.8e-126 G ABC transporter permease
NFHJGHIM_00837 3.8e-190 K Periplasmic binding protein domain
NFHJGHIM_00838 7.7e-21 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NFHJGHIM_00839 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
NFHJGHIM_00841 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NFHJGHIM_00842 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NFHJGHIM_00843 1.3e-37 yeaE S Aldo/keto reductase family
NFHJGHIM_00844 2.8e-271 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
NFHJGHIM_00845 3.6e-123 XK27_08050 O prohibitin homologues
NFHJGHIM_00846 1.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
NFHJGHIM_00847 1.3e-232 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NFHJGHIM_00848 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
NFHJGHIM_00849 3.1e-218 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NFHJGHIM_00850 0.0 macB_2 V ATPases associated with a variety of cellular activities
NFHJGHIM_00851 0.0 ctpE P E1-E2 ATPase
NFHJGHIM_00852 9.8e-55 racA K MerR, DNA binding
NFHJGHIM_00853 8.4e-198 yghZ C Aldo/keto reductase family
NFHJGHIM_00854 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
NFHJGHIM_00855 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
NFHJGHIM_00856 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
NFHJGHIM_00857 1.5e-126 S Short repeat of unknown function (DUF308)
NFHJGHIM_00858 0.0 pepO 3.4.24.71 O Peptidase family M13
NFHJGHIM_00859 7.9e-120 L Single-strand binding protein family
NFHJGHIM_00860 9e-145
NFHJGHIM_00861 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NFHJGHIM_00863 6.1e-271 recD2 3.6.4.12 L PIF1-like helicase
NFHJGHIM_00864 1.1e-158 supH S Sucrose-6F-phosphate phosphohydrolase
NFHJGHIM_00865 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NFHJGHIM_00866 2.7e-26 KT Transcriptional regulatory protein, C terminal
NFHJGHIM_00867 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
NFHJGHIM_00868 4.1e-289 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NFHJGHIM_00869 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
NFHJGHIM_00870 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
NFHJGHIM_00871 9.2e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
NFHJGHIM_00872 2e-188 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NFHJGHIM_00873 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NFHJGHIM_00874 3.9e-36 rpmE J Binds the 23S rRNA
NFHJGHIM_00876 4.7e-196 K helix_turn_helix, arabinose operon control protein
NFHJGHIM_00877 2.6e-163 glcU G Sugar transport protein
NFHJGHIM_00878 1.2e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
NFHJGHIM_00879 3.5e-257 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
NFHJGHIM_00880 2.1e-107
NFHJGHIM_00881 1.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
NFHJGHIM_00882 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
NFHJGHIM_00883 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
NFHJGHIM_00884 4.2e-164 EG EamA-like transporter family
NFHJGHIM_00887 1.7e-69 V FtsX-like permease family
NFHJGHIM_00888 1.3e-146 S Sulfite exporter TauE/SafE
NFHJGHIM_00889 1.4e-214 MA20_36090 S Psort location Cytoplasmic, score 8.87
NFHJGHIM_00890 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
NFHJGHIM_00891 6e-35 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
NFHJGHIM_00892 5.9e-77 EGP Major facilitator superfamily
NFHJGHIM_00893 3.7e-179 glkA 2.7.1.2 G ROK family
NFHJGHIM_00894 7.8e-299 S ATPases associated with a variety of cellular activities
NFHJGHIM_00895 1.2e-55 EGP Major facilitator Superfamily
NFHJGHIM_00896 1.1e-158 I alpha/beta hydrolase fold
NFHJGHIM_00897 1.1e-110 S Pyridoxamine 5'-phosphate oxidase
NFHJGHIM_00898 1.3e-55 S DUF218 domain
NFHJGHIM_00899 6.3e-17 S Protein of unknown function (DUF979)
NFHJGHIM_00900 1.7e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NFHJGHIM_00902 5.7e-126
NFHJGHIM_00903 4.7e-48 M domain, Protein
NFHJGHIM_00904 9.6e-15 M domain, Protein
NFHJGHIM_00905 2.8e-37 S Protein of unknown function (DUF3791)
NFHJGHIM_00906 1.4e-89 S Protein of unknown function (DUF3990)
NFHJGHIM_00907 2e-07
NFHJGHIM_00908 5.6e-67 fic D Fic/DOC family
NFHJGHIM_00909 3.8e-25 fic D Fic/DOC family
NFHJGHIM_00911 1.2e-97 S Domain of unknown function (DUF4825)
NFHJGHIM_00912 2.5e-43 K response regulator
NFHJGHIM_00913 2.1e-45 T response regulator
NFHJGHIM_00914 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
NFHJGHIM_00915 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
NFHJGHIM_00916 7.1e-172 tesB I Thioesterase-like superfamily
NFHJGHIM_00917 1.3e-77 S Protein of unknown function (DUF3180)
NFHJGHIM_00918 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NFHJGHIM_00919 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NFHJGHIM_00920 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
NFHJGHIM_00921 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NFHJGHIM_00922 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NFHJGHIM_00923 1.9e-211 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NFHJGHIM_00924 1e-260 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
NFHJGHIM_00925 1.1e-308
NFHJGHIM_00926 3.7e-168 natA V ATPases associated with a variety of cellular activities
NFHJGHIM_00927 3.7e-232 epsG M Glycosyl transferase family 21
NFHJGHIM_00928 4.6e-275 S AI-2E family transporter
NFHJGHIM_00929 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
NFHJGHIM_00930 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
NFHJGHIM_00933 2.6e-68 S Domain of unknown function (DUF4190)
NFHJGHIM_00934 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NFHJGHIM_00935 4e-175 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NFHJGHIM_00937 1.6e-17 S Transcription factor WhiB
NFHJGHIM_00938 2.3e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
NFHJGHIM_00939 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NFHJGHIM_00940 1.1e-89 nagA 3.5.1.25 G Amidohydrolase family
NFHJGHIM_00941 8.9e-184 lacR K Transcriptional regulator, LacI family
NFHJGHIM_00942 4e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NFHJGHIM_00943 3.9e-119 K Transcriptional regulatory protein, C terminal
NFHJGHIM_00944 4.8e-101
NFHJGHIM_00945 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
NFHJGHIM_00946 7.4e-109 ytrE V ABC transporter
NFHJGHIM_00947 1.2e-170
NFHJGHIM_00948 2.5e-12 S Psort location CytoplasmicMembrane, score 9.99
NFHJGHIM_00949 3.1e-219 vex3 V ABC transporter permease
NFHJGHIM_00950 1.6e-211 vex1 V Efflux ABC transporter, permease protein
NFHJGHIM_00951 9.9e-112 vex2 V ABC transporter, ATP-binding protein
NFHJGHIM_00952 1.4e-37 azlD E Branched-chain amino acid transport protein (AzlD)
NFHJGHIM_00953 4.8e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
NFHJGHIM_00954 1.8e-95 ptpA 3.1.3.48 T low molecular weight
NFHJGHIM_00955 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
NFHJGHIM_00956 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NFHJGHIM_00957 3.2e-71 attW O OsmC-like protein
NFHJGHIM_00958 1.6e-191 T Universal stress protein family
NFHJGHIM_00959 6e-106 M NlpC/P60 family
NFHJGHIM_00960 7.2e-181 usp 3.5.1.28 CBM50 S CHAP domain
NFHJGHIM_00961 2.5e-214 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NFHJGHIM_00962 2.6e-39
NFHJGHIM_00963 1.9e-215 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NFHJGHIM_00964 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
NFHJGHIM_00965 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NFHJGHIM_00966 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NFHJGHIM_00967 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NFHJGHIM_00969 1.6e-216 araJ EGP Major facilitator Superfamily
NFHJGHIM_00970 0.0 S Domain of unknown function (DUF4037)
NFHJGHIM_00971 1.6e-111 S Protein of unknown function (DUF4125)
NFHJGHIM_00972 1.8e-133
NFHJGHIM_00973 1.9e-290 pspC KT PspC domain
NFHJGHIM_00974 3.7e-271 tcsS3 KT PspC domain
NFHJGHIM_00975 9.2e-126 degU K helix_turn_helix, Lux Regulon
NFHJGHIM_00976 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NFHJGHIM_00978 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NFHJGHIM_00979 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
NFHJGHIM_00980 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NFHJGHIM_00981 1.5e-94
NFHJGHIM_00983 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
NFHJGHIM_00985 2.3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NFHJGHIM_00986 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
NFHJGHIM_00987 6.7e-212 I Diacylglycerol kinase catalytic domain
NFHJGHIM_00988 1.3e-151 arbG K CAT RNA binding domain
NFHJGHIM_00989 0.0 crr G pts system, glucose-specific IIABC component
NFHJGHIM_00990 6.8e-43 M Spy0128-like isopeptide containing domain
NFHJGHIM_00991 1.4e-39 M Spy0128-like isopeptide containing domain
NFHJGHIM_00993 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NFHJGHIM_00994 1.9e-259 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NFHJGHIM_00995 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
NFHJGHIM_00996 1.2e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NFHJGHIM_00997 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NFHJGHIM_00999 1e-105
NFHJGHIM_01000 3.9e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NFHJGHIM_01001 2.1e-230 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
NFHJGHIM_01002 6.9e-237 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NFHJGHIM_01003 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NFHJGHIM_01004 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NFHJGHIM_01005 5.2e-187 nusA K Participates in both transcription termination and antitermination
NFHJGHIM_01006 7.6e-164
NFHJGHIM_01007 2.5e-88 L Transposase and inactivated derivatives
NFHJGHIM_01009 1.3e-153 E Transglutaminase/protease-like homologues
NFHJGHIM_01010 0.0 gcs2 S A circularly permuted ATPgrasp
NFHJGHIM_01011 6.4e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NFHJGHIM_01012 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
NFHJGHIM_01013 2.8e-64 rplQ J Ribosomal protein L17
NFHJGHIM_01014 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NFHJGHIM_01015 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NFHJGHIM_01016 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NFHJGHIM_01017 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NFHJGHIM_01018 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NFHJGHIM_01019 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NFHJGHIM_01020 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NFHJGHIM_01021 2.7e-63 rplO J binds to the 23S rRNA
NFHJGHIM_01022 1e-24 rpmD J Ribosomal protein L30p/L7e
NFHJGHIM_01023 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NFHJGHIM_01024 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NFHJGHIM_01025 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NFHJGHIM_01026 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NFHJGHIM_01027 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NFHJGHIM_01028 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NFHJGHIM_01029 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NFHJGHIM_01030 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NFHJGHIM_01031 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NFHJGHIM_01032 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
NFHJGHIM_01033 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NFHJGHIM_01034 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NFHJGHIM_01035 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NFHJGHIM_01036 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NFHJGHIM_01037 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NFHJGHIM_01038 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NFHJGHIM_01039 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
NFHJGHIM_01040 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NFHJGHIM_01041 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
NFHJGHIM_01042 4.9e-96 ywiC S YwiC-like protein
NFHJGHIM_01043 1.8e-27 ywiC S YwiC-like protein
NFHJGHIM_01044 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NFHJGHIM_01045 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NFHJGHIM_01046 2.4e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NFHJGHIM_01047 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NFHJGHIM_01048 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
NFHJGHIM_01049 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NFHJGHIM_01050 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
NFHJGHIM_01051 3e-120
NFHJGHIM_01052 6.2e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
NFHJGHIM_01053 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
NFHJGHIM_01055 4.5e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NFHJGHIM_01056 2.3e-223 dapC E Aminotransferase class I and II
NFHJGHIM_01057 9e-61 fdxA C 4Fe-4S binding domain
NFHJGHIM_01058 1.5e-214 murB 1.3.1.98 M Cell wall formation
NFHJGHIM_01059 1.9e-25 rpmG J Ribosomal protein L33
NFHJGHIM_01063 2.2e-55 KLT Associated with various cellular activities
NFHJGHIM_01064 3.6e-129 bla1 3.5.2.6 V Beta-lactamase enzyme family
NFHJGHIM_01065 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NFHJGHIM_01066 5e-145
NFHJGHIM_01067 2e-148 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
NFHJGHIM_01068 1e-119 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
NFHJGHIM_01069 3.2e-38 fmdB S Putative regulatory protein
NFHJGHIM_01070 1.6e-109 flgA NO SAF
NFHJGHIM_01071 9.6e-42
NFHJGHIM_01072 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
NFHJGHIM_01073 3.7e-243 T Forkhead associated domain
NFHJGHIM_01075 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NFHJGHIM_01076 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NFHJGHIM_01077 5.6e-186 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
NFHJGHIM_01078 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
NFHJGHIM_01080 8.8e-222 pbuO S Permease family
NFHJGHIM_01081 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NFHJGHIM_01082 3.2e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NFHJGHIM_01083 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NFHJGHIM_01084 6.2e-180 pstA P Phosphate transport system permease
NFHJGHIM_01085 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
NFHJGHIM_01086 3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
NFHJGHIM_01087 1.3e-128 KT Transcriptional regulatory protein, C terminal
NFHJGHIM_01088 8.5e-246 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NFHJGHIM_01089 1.2e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NFHJGHIM_01090 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NFHJGHIM_01091 9.1e-107 K helix_turn_helix, Arsenical Resistance Operon Repressor
NFHJGHIM_01092 4e-243 EGP Major facilitator Superfamily
NFHJGHIM_01093 3.3e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NFHJGHIM_01094 1.5e-170 L Excalibur calcium-binding domain
NFHJGHIM_01095 3.2e-269 pepC 3.4.22.40 E Peptidase C1-like family
NFHJGHIM_01096 9.3e-44 D nuclear chromosome segregation
NFHJGHIM_01097 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NFHJGHIM_01098 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NFHJGHIM_01099 1.8e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
NFHJGHIM_01100 0.0 yegQ O Peptidase family U32 C-terminal domain
NFHJGHIM_01101 1e-53 L Transposase and inactivated derivatives IS30 family
NFHJGHIM_01102 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
NFHJGHIM_01103 2.2e-41 nrdH O Glutaredoxin
NFHJGHIM_01104 1.5e-98 nrdI F Probably involved in ribonucleotide reductase function
NFHJGHIM_01105 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFHJGHIM_01106 1.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NFHJGHIM_01107 5e-73 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NFHJGHIM_01108 0.0 S Predicted membrane protein (DUF2207)
NFHJGHIM_01109 1.4e-93 lemA S LemA family
NFHJGHIM_01110 2.3e-41 K purine nucleotide biosynthetic process
NFHJGHIM_01111 2.6e-151 xylR K purine nucleotide biosynthetic process
NFHJGHIM_01112 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NFHJGHIM_01113 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NFHJGHIM_01114 6.4e-117
NFHJGHIM_01115 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
NFHJGHIM_01117 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
NFHJGHIM_01118 1.1e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NFHJGHIM_01119 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
NFHJGHIM_01120 7.2e-308 pccB I Carboxyl transferase domain
NFHJGHIM_01121 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NFHJGHIM_01122 4.2e-93 bioY S BioY family
NFHJGHIM_01123 2.2e-151 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
NFHJGHIM_01124 0.0
NFHJGHIM_01125 5.9e-146 QT PucR C-terminal helix-turn-helix domain
NFHJGHIM_01126 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NFHJGHIM_01127 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NFHJGHIM_01128 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NFHJGHIM_01129 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NFHJGHIM_01130 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NFHJGHIM_01131 7e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NFHJGHIM_01132 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NFHJGHIM_01133 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NFHJGHIM_01135 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
NFHJGHIM_01136 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NFHJGHIM_01138 2.4e-91 L Phage integrase family
NFHJGHIM_01140 1.2e-38
NFHJGHIM_01141 2.4e-12 S Putative phage holin Dp-1
NFHJGHIM_01142 3.4e-174 K Psort location Cytoplasmic, score
NFHJGHIM_01143 7.8e-08
NFHJGHIM_01147 6.6e-180 S Prophage endopeptidase tail
NFHJGHIM_01148 1.1e-69 S phage tail
NFHJGHIM_01149 8.8e-83 NT phage tail tape measure protein
NFHJGHIM_01150 6.4e-29
NFHJGHIM_01151 1.3e-27
NFHJGHIM_01152 1.1e-59 eae N domain, Protein
NFHJGHIM_01153 1.3e-20
NFHJGHIM_01155 1e-30
NFHJGHIM_01156 3e-46 S Phage protein Gp19/Gp15/Gp42
NFHJGHIM_01158 2.3e-146 V Phage capsid family
NFHJGHIM_01159 3.1e-42
NFHJGHIM_01161 1.1e-87
NFHJGHIM_01162 2.1e-213 S Phage portal protein, SPP1 Gp6-like
NFHJGHIM_01163 5.1e-241 S Terminase
NFHJGHIM_01164 2.8e-08
NFHJGHIM_01165 9.2e-38 L HNH endonuclease
NFHJGHIM_01168 5.8e-19
NFHJGHIM_01171 2.8e-08 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NFHJGHIM_01174 2e-07
NFHJGHIM_01180 2.2e-63 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NFHJGHIM_01181 6.8e-34 V HNH endonuclease
NFHJGHIM_01182 2e-11
NFHJGHIM_01183 7e-08
NFHJGHIM_01184 2.8e-46 ssb1 L Single-stranded DNA-binding protein
NFHJGHIM_01189 7.1e-39 O prohibitin homologues
NFHJGHIM_01191 6.5e-14
NFHJGHIM_01195 9.2e-36
NFHJGHIM_01196 0.0 K RNA polymerase II activating transcription factor binding
NFHJGHIM_01197 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NFHJGHIM_01198 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NFHJGHIM_01200 1.3e-102 mntP P Probably functions as a manganese efflux pump
NFHJGHIM_01201 3.2e-125
NFHJGHIM_01202 2e-135 KT Transcriptional regulatory protein, C terminal
NFHJGHIM_01203 3e-127 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NFHJGHIM_01204 1.1e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
NFHJGHIM_01205 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NFHJGHIM_01206 0.0 S domain protein
NFHJGHIM_01207 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
NFHJGHIM_01208 2e-83 lrp_3 K helix_turn_helix ASNC type
NFHJGHIM_01209 7.2e-236 E Aminotransferase class I and II
NFHJGHIM_01210 5.1e-306 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NFHJGHIM_01211 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
NFHJGHIM_01213 3.3e-52 S Protein of unknown function (DUF2469)
NFHJGHIM_01214 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
NFHJGHIM_01215 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NFHJGHIM_01216 6.4e-290 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NFHJGHIM_01217 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NFHJGHIM_01218 1e-60 V ABC transporter
NFHJGHIM_01219 9.6e-59 V ABC transporter
NFHJGHIM_01220 2.8e-157 spoU 2.1.1.185 J RNA methyltransferase TrmH family
NFHJGHIM_01221 1e-128 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NFHJGHIM_01222 2.9e-214 rmuC S RmuC family
NFHJGHIM_01223 9.6e-43 csoR S Metal-sensitive transcriptional repressor
NFHJGHIM_01224 0.0 pacS 3.6.3.54 P E1-E2 ATPase
NFHJGHIM_01225 0.0 ubiB S ABC1 family
NFHJGHIM_01226 3.5e-19 S granule-associated protein
NFHJGHIM_01227 1.7e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NFHJGHIM_01228 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
NFHJGHIM_01229 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NFHJGHIM_01230 2.4e-251 dinF V MatE
NFHJGHIM_01231 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
NFHJGHIM_01232 1e-54 glnB K Nitrogen regulatory protein P-II
NFHJGHIM_01233 1.5e-220 amt U Ammonium Transporter Family
NFHJGHIM_01234 6.2e-203 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NFHJGHIM_01235 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
NFHJGHIM_01236 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
NFHJGHIM_01237 0.0 S Glycosyl hydrolases related to GH101 family, GH129
NFHJGHIM_01238 8.4e-306 pepD E Peptidase family C69
NFHJGHIM_01240 2.9e-19 XK26_04485 P Cobalt transport protein
NFHJGHIM_01241 1.1e-68 XK26_04485 P Cobalt transport protein
NFHJGHIM_01242 2e-82
NFHJGHIM_01243 0.0 V ABC transporter transmembrane region
NFHJGHIM_01244 1.8e-301 V ABC transporter, ATP-binding protein
NFHJGHIM_01245 2.7e-82 K Winged helix DNA-binding domain
NFHJGHIM_01246 5.8e-305 M LPXTG cell wall anchor motif
NFHJGHIM_01247 0.0 M chlorophyll binding
NFHJGHIM_01248 2.2e-88 L Transposase and inactivated derivatives IS30 family
NFHJGHIM_01249 2e-180 3.4.22.70 M Sortase family
NFHJGHIM_01251 2.6e-160 S Sucrose-6F-phosphate phosphohydrolase
NFHJGHIM_01252 6.6e-240 S Putative ABC-transporter type IV
NFHJGHIM_01253 7e-81
NFHJGHIM_01254 6.2e-35 Q phosphatase activity
NFHJGHIM_01255 4e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
NFHJGHIM_01256 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
NFHJGHIM_01257 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NFHJGHIM_01258 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NFHJGHIM_01259 2.7e-67 S haloacid dehalogenase-like hydrolase
NFHJGHIM_01261 1.4e-130 yydK K UTRA
NFHJGHIM_01262 1.3e-70 S FMN_bind
NFHJGHIM_01263 5.7e-149 macB V ABC transporter, ATP-binding protein
NFHJGHIM_01264 1.4e-202 Z012_06715 V FtsX-like permease family
NFHJGHIM_01265 1.1e-221 macB_2 V ABC transporter permease
NFHJGHIM_01266 1.4e-234 S Predicted membrane protein (DUF2318)
NFHJGHIM_01267 5.4e-108 tpd P Fe2+ transport protein
NFHJGHIM_01268 3.3e-306 efeU_1 P Iron permease FTR1 family
NFHJGHIM_01269 6.9e-23 G MFS/sugar transport protein
NFHJGHIM_01270 4.2e-200 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NFHJGHIM_01271 9.2e-57 S Fic/DOC family
NFHJGHIM_01272 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NFHJGHIM_01273 5e-38 ptsH G PTS HPr component phosphorylation site
NFHJGHIM_01274 4.4e-200 K helix_turn _helix lactose operon repressor
NFHJGHIM_01275 6.3e-213 holB 2.7.7.7 L DNA polymerase III
NFHJGHIM_01276 1.1e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NFHJGHIM_01277 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NFHJGHIM_01278 2.3e-188 3.6.1.27 I PAP2 superfamily
NFHJGHIM_01279 0.0 vpr M PA domain
NFHJGHIM_01280 8e-123 yplQ S Haemolysin-III related
NFHJGHIM_01281 5.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
NFHJGHIM_01282 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
NFHJGHIM_01283 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NFHJGHIM_01284 1.8e-278 S Calcineurin-like phosphoesterase
NFHJGHIM_01285 1.3e-281 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
NFHJGHIM_01286 1.7e-116
NFHJGHIM_01287 1.7e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NFHJGHIM_01289 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
NFHJGHIM_01290 5.3e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NFHJGHIM_01291 1.9e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NFHJGHIM_01292 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
NFHJGHIM_01293 2.2e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
NFHJGHIM_01294 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
NFHJGHIM_01295 1.1e-54 U TadE-like protein
NFHJGHIM_01296 3.2e-41 S Protein of unknown function (DUF4244)
NFHJGHIM_01297 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
NFHJGHIM_01298 1.8e-14 gspF NU Type II secretion system (T2SS), protein F
NFHJGHIM_01299 5.7e-121 U Type ii secretion system
NFHJGHIM_01300 3.4e-191 cpaF U Type II IV secretion system protein
NFHJGHIM_01301 7.5e-152 cpaE D bacterial-type flagellum organization
NFHJGHIM_01303 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NFHJGHIM_01304 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
NFHJGHIM_01305 8.6e-91
NFHJGHIM_01306 1.7e-45 cbiM P PDGLE domain
NFHJGHIM_01307 2.8e-28 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NFHJGHIM_01308 2.5e-208 S Glycosyltransferase, group 2 family protein
NFHJGHIM_01309 5.2e-262
NFHJGHIM_01311 8.7e-27 thiS 2.8.1.10 H ThiS family
NFHJGHIM_01312 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NFHJGHIM_01313 0.0 S Psort location Cytoplasmic, score 8.87
NFHJGHIM_01314 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
NFHJGHIM_01315 1.1e-246 V ABC transporter permease
NFHJGHIM_01316 2.9e-182 V ABC transporter
NFHJGHIM_01317 1.9e-138 T HD domain
NFHJGHIM_01318 6.8e-164 S Glutamine amidotransferase domain
NFHJGHIM_01320 0.0 kup P Transport of potassium into the cell
NFHJGHIM_01321 5.9e-185 tatD L TatD related DNase
NFHJGHIM_01322 1.2e-197 xylR 5.3.1.12 G MFS/sugar transport protein
NFHJGHIM_01323 1.5e-37 xylR 5.3.1.12 G MFS/sugar transport protein
NFHJGHIM_01325 2.9e-79 K Transcriptional regulator
NFHJGHIM_01326 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NFHJGHIM_01327 1e-129
NFHJGHIM_01328 8.6e-59
NFHJGHIM_01329 2.3e-168 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NFHJGHIM_01330 2.7e-126 dedA S SNARE associated Golgi protein
NFHJGHIM_01332 3.5e-134 S HAD hydrolase, family IA, variant 3
NFHJGHIM_01333 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
NFHJGHIM_01334 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
NFHJGHIM_01335 6.8e-87 hspR K transcriptional regulator, MerR family
NFHJGHIM_01336 1.1e-170 dnaJ1 O DnaJ molecular chaperone homology domain
NFHJGHIM_01337 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NFHJGHIM_01338 0.0 dnaK O Heat shock 70 kDa protein
NFHJGHIM_01339 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
NFHJGHIM_01340 2.9e-190 K Psort location Cytoplasmic, score
NFHJGHIM_01342 1.2e-131 G Phosphoglycerate mutase family
NFHJGHIM_01343 1.6e-69 S Protein of unknown function (DUF4235)
NFHJGHIM_01344 1.1e-28 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
NFHJGHIM_01345 1.5e-247 3.5.1.104 G Polysaccharide deacetylase
NFHJGHIM_01346 3.3e-200 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
NFHJGHIM_01347 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NFHJGHIM_01348 3.7e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NFHJGHIM_01349 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NFHJGHIM_01350 5.6e-197 K helix_turn _helix lactose operon repressor
NFHJGHIM_01351 1.1e-77 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
NFHJGHIM_01352 3.2e-295 scrT G Transporter major facilitator family protein
NFHJGHIM_01353 5e-254 yhjE EGP Sugar (and other) transporter
NFHJGHIM_01354 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NFHJGHIM_01355 8.2e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NFHJGHIM_01356 2.6e-183 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
NFHJGHIM_01357 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NFHJGHIM_01358 1.8e-276 aroP E aromatic amino acid transport protein AroP K03293
NFHJGHIM_01359 2.4e-101 K Transcriptional regulator C-terminal region
NFHJGHIM_01360 2.6e-129 V ABC transporter
NFHJGHIM_01361 0.0 V FtsX-like permease family
NFHJGHIM_01362 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NFHJGHIM_01363 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NFHJGHIM_01364 1.1e-37 E ABC transporter
NFHJGHIM_01365 2.9e-99 bcp 1.11.1.15 O Redoxin
NFHJGHIM_01366 7.4e-151 S Virulence factor BrkB
NFHJGHIM_01367 4.2e-42 XAC3035 O Glutaredoxin
NFHJGHIM_01368 1.2e-105 L Transposase
NFHJGHIM_01369 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NFHJGHIM_01370 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NFHJGHIM_01371 5.5e-55 L HNH endonuclease
NFHJGHIM_01372 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NFHJGHIM_01373 1.2e-132
NFHJGHIM_01374 5e-266 EGP Major Facilitator Superfamily
NFHJGHIM_01375 3.5e-41 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
NFHJGHIM_01376 9.7e-45 L Integrase core domain
NFHJGHIM_01379 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NFHJGHIM_01380 1.6e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
NFHJGHIM_01382 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NFHJGHIM_01383 6.4e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NFHJGHIM_01384 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NFHJGHIM_01385 6.5e-281 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NFHJGHIM_01386 3.4e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
NFHJGHIM_01387 5e-156 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NFHJGHIM_01388 7.4e-180 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NFHJGHIM_01389 1.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NFHJGHIM_01390 1.3e-24 K MerR family regulatory protein
NFHJGHIM_01391 3.1e-195 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NFHJGHIM_01392 2.8e-141
NFHJGHIM_01394 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NFHJGHIM_01395 4.4e-242 vbsD V MatE
NFHJGHIM_01396 7.3e-132 S Enoyl-(Acyl carrier protein) reductase
NFHJGHIM_01397 2.3e-133 magIII L endonuclease III
NFHJGHIM_01398 3.8e-93 laaE K Transcriptional regulator PadR-like family
NFHJGHIM_01399 5.2e-176 S Membrane transport protein
NFHJGHIM_01400 1.1e-67 4.1.1.44 S Cupin domain
NFHJGHIM_01401 5.9e-224 hipA 2.7.11.1 S HipA N-terminal domain
NFHJGHIM_01402 3.7e-41 K Helix-turn-helix
NFHJGHIM_01403 2.2e-47 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
NFHJGHIM_01404 5.4e-19
NFHJGHIM_01405 1.9e-101 K Bacterial regulatory proteins, tetR family
NFHJGHIM_01406 3.3e-86 T Domain of unknown function (DUF4234)
NFHJGHIM_01407 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
NFHJGHIM_01408 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NFHJGHIM_01409 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NFHJGHIM_01410 2.2e-142 4.1.1.44 S Carboxymuconolactone decarboxylase family
NFHJGHIM_01411 1.3e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
NFHJGHIM_01413 2.6e-288 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
NFHJGHIM_01414 0.0 pafB K WYL domain
NFHJGHIM_01415 7e-53
NFHJGHIM_01416 0.0 helY L DEAD DEAH box helicase
NFHJGHIM_01417 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NFHJGHIM_01418 3.6e-142 pgp 3.1.3.18 S HAD-hyrolase-like
NFHJGHIM_01421 8.1e-90 K Putative zinc ribbon domain
NFHJGHIM_01422 9.7e-67 S GyrI-like small molecule binding domain
NFHJGHIM_01423 1.8e-22 L DNA integration
NFHJGHIM_01424 5.5e-15
NFHJGHIM_01425 7.3e-62
NFHJGHIM_01426 2.7e-120 K helix_turn_helix, mercury resistance
NFHJGHIM_01427 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
NFHJGHIM_01428 7.7e-141 S Bacterial protein of unknown function (DUF881)
NFHJGHIM_01429 2.6e-31 sbp S Protein of unknown function (DUF1290)
NFHJGHIM_01430 1.4e-173 S Bacterial protein of unknown function (DUF881)
NFHJGHIM_01431 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NFHJGHIM_01432 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
NFHJGHIM_01433 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
NFHJGHIM_01434 6.9e-100 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
NFHJGHIM_01435 4.5e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NFHJGHIM_01436 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NFHJGHIM_01437 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NFHJGHIM_01438 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
NFHJGHIM_01439 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NFHJGHIM_01440 5.5e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NFHJGHIM_01441 5.7e-30
NFHJGHIM_01442 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NFHJGHIM_01443 1.9e-245
NFHJGHIM_01444 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NFHJGHIM_01445 3.3e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NFHJGHIM_01446 1.6e-100 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NFHJGHIM_01447 8e-41 yajC U Preprotein translocase subunit
NFHJGHIM_01448 1.9e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NFHJGHIM_01449 7.3e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NFHJGHIM_01451 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NFHJGHIM_01452 1e-131 yebC K transcriptional regulatory protein
NFHJGHIM_01453 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
NFHJGHIM_01454 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NFHJGHIM_01455 1.4e-249 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NFHJGHIM_01458 8.3e-261
NFHJGHIM_01459 3.5e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NFHJGHIM_01460 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
NFHJGHIM_01461 4.4e-118 safC S O-methyltransferase
NFHJGHIM_01462 6.6e-184 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
NFHJGHIM_01463 3e-71 yraN L Belongs to the UPF0102 family
NFHJGHIM_01464 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
NFHJGHIM_01465 2.2e-282 dprA 5.99.1.2 LU DNA recombination-mediator protein A
NFHJGHIM_01466 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
NFHJGHIM_01467 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NFHJGHIM_01468 2.1e-157 S Putative ABC-transporter type IV
NFHJGHIM_01469 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
NFHJGHIM_01470 4e-162 V ABC transporter, ATP-binding protein
NFHJGHIM_01471 0.0 MV MacB-like periplasmic core domain
NFHJGHIM_01472 0.0 phoN I PAP2 superfamily
NFHJGHIM_01473 6.1e-132 K helix_turn_helix, Lux Regulon
NFHJGHIM_01474 0.0 tcsS2 T Histidine kinase
NFHJGHIM_01475 1.9e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
NFHJGHIM_01476 3.2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NFHJGHIM_01477 1.9e-167 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
NFHJGHIM_01478 1.4e-147 P NLPA lipoprotein
NFHJGHIM_01479 7.7e-188 acoA 1.2.4.1 C Dehydrogenase E1 component
NFHJGHIM_01480 2.3e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
NFHJGHIM_01481 3e-204 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NFHJGHIM_01482 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
NFHJGHIM_01483 5.4e-228 mtnE 2.6.1.83 E Aminotransferase class I and II
NFHJGHIM_01484 3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NFHJGHIM_01485 3.1e-194 int L Phage integrase, N-terminal SAM-like domain
NFHJGHIM_01486 1.7e-27 S Protein of unknown function (DUF3800)
NFHJGHIM_01487 9.7e-30
NFHJGHIM_01488 6.8e-08 int L Phage integrase, N-terminal SAM-like domain
NFHJGHIM_01489 2.6e-119 dprA LU DNA recombination-mediator protein A
NFHJGHIM_01490 8.2e-61 S competence protein
NFHJGHIM_01491 3.4e-09
NFHJGHIM_01494 4.6e-16
NFHJGHIM_01495 4.9e-49 L Integrase core domain
NFHJGHIM_01496 1.7e-168 G ABC transporter permease
NFHJGHIM_01497 1.1e-173 G Binding-protein-dependent transport system inner membrane component
NFHJGHIM_01498 4.3e-247 G Bacterial extracellular solute-binding protein
NFHJGHIM_01499 4.2e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NFHJGHIM_01500 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NFHJGHIM_01501 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NFHJGHIM_01502 9.8e-230 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NFHJGHIM_01503 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
NFHJGHIM_01504 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NFHJGHIM_01505 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NFHJGHIM_01506 1e-127 3.2.1.8 S alpha beta
NFHJGHIM_01507 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NFHJGHIM_01508 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
NFHJGHIM_01509 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NFHJGHIM_01510 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
NFHJGHIM_01511 5.7e-91
NFHJGHIM_01512 2.1e-199 guaB 1.1.1.205 F IMP dehydrogenase family protein
NFHJGHIM_01513 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
NFHJGHIM_01514 3.2e-276 G ABC transporter substrate-binding protein
NFHJGHIM_01515 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
NFHJGHIM_01516 6e-131 M Peptidase family M23
NFHJGHIM_01518 9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NFHJGHIM_01519 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
NFHJGHIM_01520 2.7e-160 yeaZ 2.3.1.234 O Glycoprotease family
NFHJGHIM_01521 3.8e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
NFHJGHIM_01522 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
NFHJGHIM_01523 0.0 comE S Competence protein
NFHJGHIM_01524 7.4e-96 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
NFHJGHIM_01525 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NFHJGHIM_01526 1.1e-164 ET Bacterial periplasmic substrate-binding proteins
NFHJGHIM_01527 4.8e-171 corA P CorA-like Mg2+ transporter protein
NFHJGHIM_01528 1.2e-160 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NFHJGHIM_01529 1.5e-299 E Serine carboxypeptidase
NFHJGHIM_01530 0.0 S Psort location Cytoplasmic, score 8.87
NFHJGHIM_01531 5.7e-109 S Domain of unknown function (DUF4194)
NFHJGHIM_01532 7.5e-283 S Psort location Cytoplasmic, score 8.87
NFHJGHIM_01533 1.4e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NFHJGHIM_01534 7.6e-64 yeaO K Protein of unknown function, DUF488
NFHJGHIM_01535 8.6e-121 ydaF_1 J Acetyltransferase (GNAT) domain
NFHJGHIM_01536 8.3e-90 MA20_25245 K FR47-like protein
NFHJGHIM_01537 4.3e-56 K Transcriptional regulator
NFHJGHIM_01538 1.3e-100 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
NFHJGHIM_01539 5.2e-31 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NFHJGHIM_01541 1.3e-184 S Acetyltransferase (GNAT) domain
NFHJGHIM_01542 1.3e-73 qseC 2.7.13.3 T Histidine kinase
NFHJGHIM_01543 1.4e-132 S SOS response associated peptidase (SRAP)
NFHJGHIM_01544 3.2e-124
NFHJGHIM_01545 1.6e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NFHJGHIM_01546 3.4e-164 rpoC M heme binding
NFHJGHIM_01547 5.4e-100 EGP Major facilitator Superfamily
NFHJGHIM_01549 2.2e-149
NFHJGHIM_01550 1.5e-95 ypjC S Putative ABC-transporter type IV
NFHJGHIM_01551 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
NFHJGHIM_01552 2.4e-192 V VanZ like family
NFHJGHIM_01553 4.2e-147 KT RESPONSE REGULATOR receiver
NFHJGHIM_01554 2.7e-70 pdxH S Pfam:Pyridox_oxidase
NFHJGHIM_01555 3.1e-143 yijF S Domain of unknown function (DUF1287)
NFHJGHIM_01556 5e-133 C Putative TM nitroreductase
NFHJGHIM_01557 3e-101
NFHJGHIM_01559 1.2e-254 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
NFHJGHIM_01560 1.7e-78 S Bacterial PH domain
NFHJGHIM_01561 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NFHJGHIM_01562 2.1e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NFHJGHIM_01563 1.6e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NFHJGHIM_01565 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NFHJGHIM_01566 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NFHJGHIM_01567 1.3e-91
NFHJGHIM_01568 5.3e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NFHJGHIM_01569 2.5e-283 thrC 4.2.3.1 E Threonine synthase N terminus
NFHJGHIM_01570 8.1e-123 S ABC-2 family transporter protein
NFHJGHIM_01571 3.7e-126 S ABC-2 family transporter protein
NFHJGHIM_01572 2e-177 V ATPases associated with a variety of cellular activities
NFHJGHIM_01573 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
NFHJGHIM_01574 3.4e-123 S Haloacid dehalogenase-like hydrolase
NFHJGHIM_01575 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
NFHJGHIM_01576 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NFHJGHIM_01577 1.1e-230 trkB P Cation transport protein
NFHJGHIM_01578 6.8e-116 trkA P TrkA-N domain
NFHJGHIM_01579 3.6e-104
NFHJGHIM_01580 1.4e-136 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NFHJGHIM_01582 2.3e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NFHJGHIM_01583 3.7e-159 L Tetratricopeptide repeat
NFHJGHIM_01584 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NFHJGHIM_01585 1.6e-143 S Putative ABC-transporter type IV
NFHJGHIM_01586 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NFHJGHIM_01587 5.2e-281 argH 4.3.2.1 E argininosuccinate lyase
NFHJGHIM_01588 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NFHJGHIM_01589 2.8e-277 K Putative DNA-binding domain
NFHJGHIM_01590 1.3e-142 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
NFHJGHIM_01591 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
NFHJGHIM_01592 8.9e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NFHJGHIM_01593 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NFHJGHIM_01594 2.2e-304 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NFHJGHIM_01595 5.5e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NFHJGHIM_01596 6.4e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
NFHJGHIM_01597 2.3e-240 hom 1.1.1.3 E Homoserine dehydrogenase
NFHJGHIM_01598 3.5e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NFHJGHIM_01599 9.5e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
NFHJGHIM_01600 5.8e-67
NFHJGHIM_01601 2.1e-58
NFHJGHIM_01602 4.9e-165 V ATPases associated with a variety of cellular activities
NFHJGHIM_01603 3.3e-256 V Efflux ABC transporter, permease protein
NFHJGHIM_01604 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
NFHJGHIM_01605 2.4e-239 dapE 3.5.1.18 E Peptidase dimerisation domain
NFHJGHIM_01606 0.0 rne 3.1.26.12 J Ribonuclease E/G family
NFHJGHIM_01607 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
NFHJGHIM_01608 3.1e-40 rpmA J Ribosomal L27 protein
NFHJGHIM_01609 7.5e-216 K Psort location Cytoplasmic, score
NFHJGHIM_01610 3.7e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NFHJGHIM_01611 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NFHJGHIM_01612 2e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
NFHJGHIM_01614 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NFHJGHIM_01615 1.4e-108 nusG K Participates in transcription elongation, termination and antitermination
NFHJGHIM_01616 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
NFHJGHIM_01617 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NFHJGHIM_01618 3.4e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NFHJGHIM_01619 2.8e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NFHJGHIM_01620 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
NFHJGHIM_01621 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NFHJGHIM_01622 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NFHJGHIM_01623 2e-116
NFHJGHIM_01624 3.1e-161 T Pfam Adenylate and Guanylate cyclase catalytic domain
NFHJGHIM_01625 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NFHJGHIM_01626 1.1e-79 ssb1 L Single-stranded DNA-binding protein
NFHJGHIM_01627 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NFHJGHIM_01628 6.6e-70 rplI J Binds to the 23S rRNA
NFHJGHIM_01630 2.4e-35 S Parallel beta-helix repeats
NFHJGHIM_01631 1e-69 E Domain of unknown function (DUF5011)
NFHJGHIM_01633 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NFHJGHIM_01634 1.3e-129 M Protein of unknown function (DUF3152)
NFHJGHIM_01635 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
NFHJGHIM_01636 3.2e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NFHJGHIM_01637 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
NFHJGHIM_01638 0.0 inlJ M domain protein
NFHJGHIM_01639 4.6e-283 M LPXTG cell wall anchor motif
NFHJGHIM_01640 3.7e-213 3.4.22.70 M Sortase family
NFHJGHIM_01641 1.3e-60 S Domain of unknown function (DUF4854)
NFHJGHIM_01642 2.4e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
NFHJGHIM_01643 9.6e-30 2.1.1.72 S Protein conserved in bacteria
NFHJGHIM_01644 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NFHJGHIM_01645 1.6e-132 M Mechanosensitive ion channel
NFHJGHIM_01646 5e-119 K Bacterial regulatory proteins, tetR family
NFHJGHIM_01647 5e-240 MA20_36090 S Psort location Cytoplasmic, score 8.87
NFHJGHIM_01648 4.2e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
NFHJGHIM_01649 1.1e-23 M Belongs to the glycosyl hydrolase 28 family
NFHJGHIM_01651 3e-41 K Transcriptional regulator
NFHJGHIM_01652 3e-60 fadD 6.2.1.3 I AMP-binding enzyme
NFHJGHIM_01653 1.1e-13 fadD 6.2.1.3 I AMP-binding enzyme
NFHJGHIM_01654 2.6e-55 fadD 6.2.1.3 I AMP-binding enzyme
NFHJGHIM_01655 3.5e-07 S Scramblase
NFHJGHIM_01656 1.6e-32
NFHJGHIM_01659 1.6e-07 L DNA integration
NFHJGHIM_01660 1.6e-37 L Phage integrase family
NFHJGHIM_01661 6.7e-35 D FtsK/SpoIIIE family
NFHJGHIM_01663 3.4e-52 S Eco47II restriction endonuclease
NFHJGHIM_01664 8.6e-163 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
NFHJGHIM_01665 4e-22 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
NFHJGHIM_01666 1e-98 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
NFHJGHIM_01667 2.8e-199 K Helix-turn-helix XRE-family like proteins
NFHJGHIM_01668 2.6e-24 K Helix-turn-helix XRE-family like proteins
NFHJGHIM_01669 3.7e-54 relB L RelB antitoxin
NFHJGHIM_01670 1.3e-08 T Toxic component of a toxin-antitoxin (TA) module
NFHJGHIM_01671 1.7e-131 K helix_turn_helix, mercury resistance
NFHJGHIM_01672 6.6e-243 yxiO S Vacuole effluxer Atg22 like
NFHJGHIM_01674 6.5e-201 yegV G pfkB family carbohydrate kinase
NFHJGHIM_01675 1.4e-29 rpmB J Ribosomal L28 family
NFHJGHIM_01676 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
NFHJGHIM_01677 3.2e-207 steT E Amino acid permease
NFHJGHIM_01680 0.0
NFHJGHIM_01681 1.3e-248 U Sodium:dicarboxylate symporter family
NFHJGHIM_01682 8.9e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
NFHJGHIM_01683 4.5e-106 XK27_02070 S Nitroreductase family
NFHJGHIM_01684 3.8e-81 hsp20 O Hsp20/alpha crystallin family
NFHJGHIM_01685 4.1e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NFHJGHIM_01686 2.9e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NFHJGHIM_01687 1.8e-34 CP_0960 S Belongs to the UPF0109 family
NFHJGHIM_01688 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NFHJGHIM_01689 8.5e-295 ydfD EK Alanine-glyoxylate amino-transferase
NFHJGHIM_01690 1.3e-93 argO S LysE type translocator
NFHJGHIM_01691 4.1e-220 S Endonuclease/Exonuclease/phosphatase family
NFHJGHIM_01692 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NFHJGHIM_01693 1.4e-164 P Cation efflux family
NFHJGHIM_01694 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
NFHJGHIM_01695 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
NFHJGHIM_01696 0.0 yjjK S ABC transporter
NFHJGHIM_01697 2e-58 S Protein of unknown function (DUF3039)
NFHJGHIM_01698 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NFHJGHIM_01699 3.6e-107
NFHJGHIM_01700 1e-113 yceD S Uncharacterized ACR, COG1399
NFHJGHIM_01701 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NFHJGHIM_01702 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NFHJGHIM_01703 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
NFHJGHIM_01704 7.6e-92 ilvN 2.2.1.6 E ACT domain
NFHJGHIM_01707 1.3e-246 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NFHJGHIM_01708 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NFHJGHIM_01709 4.8e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NFHJGHIM_01710 6.4e-174 S Auxin Efflux Carrier
NFHJGHIM_01713 0.0 pgi 5.3.1.9 G Belongs to the GPI family
NFHJGHIM_01714 1.5e-190
NFHJGHIM_01716 6.9e-201
NFHJGHIM_01718 5.5e-122 mgtC S MgtC family
NFHJGHIM_01719 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
NFHJGHIM_01720 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
NFHJGHIM_01721 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
NFHJGHIM_01723 3.2e-30 K Putative sugar-binding domain
NFHJGHIM_01724 1.5e-96 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
NFHJGHIM_01725 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NFHJGHIM_01726 1.3e-156 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NFHJGHIM_01727 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NFHJGHIM_01728 6.4e-207 K helix_turn _helix lactose operon repressor
NFHJGHIM_01729 0.0 fadD 6.2.1.3 I AMP-binding enzyme
NFHJGHIM_01730 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NFHJGHIM_01731 3.7e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NFHJGHIM_01734 7.7e-175 G Glycosyl hydrolases family 43
NFHJGHIM_01735 2.5e-103 G Glycosyl hydrolases family 43
NFHJGHIM_01736 1.2e-200 K helix_turn _helix lactose operon repressor
NFHJGHIM_01737 2.4e-11 E Domain of unknown function (DUF5011)
NFHJGHIM_01738 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
NFHJGHIM_01739 2.1e-134 L Protein of unknown function (DUF1524)
NFHJGHIM_01740 8.8e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NFHJGHIM_01741 1.5e-305 EGP Major facilitator Superfamily
NFHJGHIM_01742 1.7e-205
NFHJGHIM_01743 5e-179 S G5
NFHJGHIM_01744 2.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
NFHJGHIM_01745 4.8e-119 F Domain of unknown function (DUF4916)
NFHJGHIM_01746 2.6e-160 mhpC I Alpha/beta hydrolase family
NFHJGHIM_01747 1.1e-206 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
NFHJGHIM_01748 0.0 enhA_2 S L,D-transpeptidase catalytic domain
NFHJGHIM_01749 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NFHJGHIM_01750 2.6e-239 S Uncharacterized conserved protein (DUF2183)
NFHJGHIM_01751 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
NFHJGHIM_01752 2e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NFHJGHIM_01753 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
NFHJGHIM_01754 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
NFHJGHIM_01755 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
NFHJGHIM_01756 6.3e-218 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
NFHJGHIM_01757 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NFHJGHIM_01758 3.1e-139 glpR K DeoR C terminal sensor domain
NFHJGHIM_01759 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
NFHJGHIM_01760 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
NFHJGHIM_01761 8.6e-243 EGP Sugar (and other) transporter
NFHJGHIM_01762 4.2e-43 gcvR T Belongs to the UPF0237 family
NFHJGHIM_01763 9.4e-253 S UPF0210 protein
NFHJGHIM_01764 1.9e-72
NFHJGHIM_01767 5.7e-163 IQ KR domain
NFHJGHIM_01768 1e-63 4.2.1.68 M Enolase C-terminal domain-like
NFHJGHIM_01769 1.6e-17 4.2.1.68 M carboxylic acid catabolic process
NFHJGHIM_01770 1.4e-184 K Bacterial regulatory proteins, lacI family
NFHJGHIM_01772 2.8e-119 cyaA 4.6.1.1 S CYTH
NFHJGHIM_01773 3.8e-163 trxA2 O Tetratricopeptide repeat
NFHJGHIM_01774 7.9e-180
NFHJGHIM_01775 6e-186
NFHJGHIM_01776 9.8e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
NFHJGHIM_01777 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NFHJGHIM_01778 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NFHJGHIM_01779 9.2e-127
NFHJGHIM_01780 2.1e-131 K Bacterial regulatory proteins, tetR family
NFHJGHIM_01781 2.6e-223 G Transmembrane secretion effector
NFHJGHIM_01782 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NFHJGHIM_01783 6.1e-221 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
NFHJGHIM_01784 7.1e-182 S CAAX protease self-immunity
NFHJGHIM_01786 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
NFHJGHIM_01787 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NFHJGHIM_01788 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NFHJGHIM_01789 9.1e-137 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
NFHJGHIM_01790 1.3e-251 S Calcineurin-like phosphoesterase
NFHJGHIM_01793 6.8e-83 S Domain of unknown function (DUF4143)
NFHJGHIM_01794 9.8e-277 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NFHJGHIM_01796 3.1e-124 S HAD hydrolase, family IA, variant 3
NFHJGHIM_01797 5.5e-200 P NMT1/THI5 like
NFHJGHIM_01798 5.8e-138 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
NFHJGHIM_01799 2.7e-142
NFHJGHIM_01800 4e-124 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
NFHJGHIM_01801 6.2e-263 EGP Major facilitator Superfamily
NFHJGHIM_01802 6.8e-98 S GtrA-like protein
NFHJGHIM_01803 1.3e-62 S Macrophage migration inhibitory factor (MIF)
NFHJGHIM_01804 1.9e-286 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
NFHJGHIM_01805 0.0 pepD E Peptidase family C69
NFHJGHIM_01806 4.9e-107 S Phosphatidylethanolamine-binding protein
NFHJGHIM_01807 6.6e-123 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
NFHJGHIM_01809 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
NFHJGHIM_01810 2.2e-16 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
NFHJGHIM_01811 1.4e-22 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
NFHJGHIM_01813 0.0 lmrA2 V ABC transporter transmembrane region
NFHJGHIM_01814 0.0 lmrA1 V ABC transporter, ATP-binding protein
NFHJGHIM_01815 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
NFHJGHIM_01816 2.2e-190 1.1.1.65 C Aldo/keto reductase family
NFHJGHIM_01818 4e-100 M Belongs to the glycosyl hydrolase 30 family
NFHJGHIM_01819 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
NFHJGHIM_01821 4.4e-259 L Phage integrase, N-terminal SAM-like domain
NFHJGHIM_01822 6.5e-136 pgm3 G Phosphoglycerate mutase family
NFHJGHIM_01823 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
NFHJGHIM_01824 1.1e-36
NFHJGHIM_01825 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NFHJGHIM_01826 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NFHJGHIM_01827 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NFHJGHIM_01828 1.3e-47 3.4.23.43 S Type IV leader peptidase family
NFHJGHIM_01829 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NFHJGHIM_01830 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NFHJGHIM_01831 5.9e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NFHJGHIM_01832 7.3e-75
NFHJGHIM_01833 1.7e-120 K helix_turn_helix, Lux Regulon
NFHJGHIM_01834 5.2e-08 3.4.22.70 M Sortase family
NFHJGHIM_01835 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NFHJGHIM_01836 3.6e-290 sufB O FeS assembly protein SufB
NFHJGHIM_01837 2.6e-233 sufD O FeS assembly protein SufD
NFHJGHIM_01838 1.4e-144 sufC O FeS assembly ATPase SufC
NFHJGHIM_01839 3.5e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NFHJGHIM_01840 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
NFHJGHIM_01841 1.2e-108 yitW S Iron-sulfur cluster assembly protein
NFHJGHIM_01842 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NFHJGHIM_01843 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
NFHJGHIM_01845 7.2e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NFHJGHIM_01846 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
NFHJGHIM_01847 1.7e-196 phoH T PhoH-like protein
NFHJGHIM_01848 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NFHJGHIM_01849 1.2e-250 corC S CBS domain
NFHJGHIM_01850 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NFHJGHIM_01851 0.0 fadD 6.2.1.3 I AMP-binding enzyme
NFHJGHIM_01852 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
NFHJGHIM_01853 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
NFHJGHIM_01854 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NFHJGHIM_01855 4.8e-190 S alpha beta
NFHJGHIM_01856 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NFHJGHIM_01857 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
NFHJGHIM_01858 4e-46 S phosphoesterase or phosphohydrolase
NFHJGHIM_01859 2.7e-99 3.1.4.37 T RNA ligase
NFHJGHIM_01860 1.2e-135 S UPF0126 domain
NFHJGHIM_01861 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
NFHJGHIM_01862 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NFHJGHIM_01863 1.1e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
NFHJGHIM_01864 4e-13 S Membrane
NFHJGHIM_01865 3e-287 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
NFHJGHIM_01866 0.0 tetP J Elongation factor G, domain IV
NFHJGHIM_01867 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
NFHJGHIM_01868 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NFHJGHIM_01869 3.6e-82
NFHJGHIM_01870 1.9e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
NFHJGHIM_01871 8.9e-164 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
NFHJGHIM_01872 4.1e-161 ybeM S Carbon-nitrogen hydrolase
NFHJGHIM_01873 3.2e-118 S Sel1-like repeats.
NFHJGHIM_01874 2.6e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NFHJGHIM_01875 1.7e-61 S Short C-terminal domain
NFHJGHIM_01876 1.8e-140 L Transposase
NFHJGHIM_01877 1.6e-28
NFHJGHIM_01878 1.3e-48 V Abi-like protein
NFHJGHIM_01879 1.1e-126 XK26_04895
NFHJGHIM_01881 1e-223 K Helix-turn-helix domain protein
NFHJGHIM_01883 4.3e-152 F nucleoside 2-deoxyribosyltransferase
NFHJGHIM_01884 7.6e-14 CP_0667 3.6.1.13 S phosphatase homologous to the C-terminal domain of histone macroH2A1
NFHJGHIM_01885 0.0 2.1.1.72, 3.1.21.3, 3.1.21.4 L T5orf172
NFHJGHIM_01886 3e-192 2.1.1.72, 3.1.21.4 V Eco57I restriction-modification methylase
NFHJGHIM_01887 8.8e-89 2.1.1.72, 3.1.21.4 V Eco57I restriction-modification methylase
NFHJGHIM_01888 3.7e-105 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NFHJGHIM_01889 0.0 S Protein of unknown function DUF262
NFHJGHIM_01890 1e-30
NFHJGHIM_01891 1.3e-93 rarD 3.4.17.13 E Rard protein
NFHJGHIM_01892 5.3e-23 rarD S Rard protein
NFHJGHIM_01893 7.9e-179 I alpha/beta hydrolase fold
NFHJGHIM_01894 7.4e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NFHJGHIM_01895 2.6e-100 sixA T Phosphoglycerate mutase family
NFHJGHIM_01896 1.9e-241 int L Phage integrase, N-terminal SAM-like domain
NFHJGHIM_01897 7.9e-22
NFHJGHIM_01898 2.4e-34
NFHJGHIM_01899 6.6e-232 S Protein of unknown function DUF262
NFHJGHIM_01900 5e-50
NFHJGHIM_01901 1.4e-104 S Virulence protein RhuM family
NFHJGHIM_01903 8.4e-52
NFHJGHIM_01904 1.5e-133 K BRO family, N-terminal domain
NFHJGHIM_01906 2.2e-37
NFHJGHIM_01908 1.2e-35
NFHJGHIM_01910 9.5e-92 ssb1 L Single-strand binding protein family
NFHJGHIM_01911 2.5e-269 K ParB-like nuclease domain
NFHJGHIM_01912 7.2e-140 K Transcriptional regulator
NFHJGHIM_01913 1.2e-23
NFHJGHIM_01914 1.3e-80 V HNH endonuclease
NFHJGHIM_01915 8.7e-107 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NFHJGHIM_01917 4.6e-46
NFHJGHIM_01919 4.8e-142
NFHJGHIM_01920 6.2e-34 N HicA toxin of bacterial toxin-antitoxin,
NFHJGHIM_01921 1.3e-72 S HicB_like antitoxin of bacterial toxin-antitoxin system
NFHJGHIM_01923 3.2e-32 K Transcriptional regulator
NFHJGHIM_01926 8.1e-66
NFHJGHIM_01927 2e-114 S Bifunctional DNA primase/polymerase, N-terminal
NFHJGHIM_01928 4.8e-69
NFHJGHIM_01929 0.0 S Terminase
NFHJGHIM_01930 6e-279 S Phage portal protein, SPP1 Gp6-like
NFHJGHIM_01931 2.8e-240
NFHJGHIM_01932 1.1e-43
NFHJGHIM_01933 9.6e-95
NFHJGHIM_01934 1.5e-175 S Phage capsid family
NFHJGHIM_01935 1.4e-64
NFHJGHIM_01936 9.8e-91
NFHJGHIM_01937 1.3e-78
NFHJGHIM_01938 6.1e-73
NFHJGHIM_01939 4.9e-72
NFHJGHIM_01940 1.2e-94
NFHJGHIM_01941 2.9e-82
NFHJGHIM_01942 6.3e-53
NFHJGHIM_01943 0.0 S Phage-related minor tail protein
NFHJGHIM_01944 4.7e-148 S phage tail
NFHJGHIM_01945 0.0 S Prophage endopeptidase tail
NFHJGHIM_01946 1e-66
NFHJGHIM_01948 3.2e-109
NFHJGHIM_01950 8.9e-54 MU outer membrane autotransporter barrel domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)