ORF_ID e_value Gene_name EC_number CAZy COGs Description
NKPELAJD_00001 3.6e-115 D Phage-related minor tail protein
NKPELAJD_00002 5.6e-38 S Bacteriophage Gp15 protein
NKPELAJD_00003 1.5e-14
NKPELAJD_00004 3.2e-09 chiB 3.2.1.14 GH18 G Carbohydrate binding domain
NKPELAJD_00005 1.8e-07 malS 3.2.1.1 GH13 G Carbohydrate binding domain
NKPELAJD_00006 5.4e-43 N Belongs to the glycosyl hydrolase family 6
NKPELAJD_00007 1.2e-22 S Minor capsid protein from bacteriophage
NKPELAJD_00008 2.7e-31 S Minor capsid protein
NKPELAJD_00009 1.4e-16 S Minor capsid protein
NKPELAJD_00010 3.3e-28
NKPELAJD_00011 7.4e-13
NKPELAJD_00013 2.8e-120
NKPELAJD_00014 2.6e-35
NKPELAJD_00016 2.9e-90 S Phage minor capsid protein 2
NKPELAJD_00017 6.7e-164 S portal protein
NKPELAJD_00018 1.3e-203 S Phage terminase, large subunit, PBSX family
NKPELAJD_00019 3.9e-31 xtmA L Terminase small subunit
NKPELAJD_00021 3.9e-34 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NKPELAJD_00023 2.6e-29 sigF K sigma factor activity
NKPELAJD_00026 1.8e-24
NKPELAJD_00028 1.2e-17
NKPELAJD_00034 3.8e-07
NKPELAJD_00037 4.9e-57 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NKPELAJD_00038 4.7e-38 S Recombination protein U
NKPELAJD_00042 3e-79 S ERF superfamily
NKPELAJD_00043 1.6e-50 S Bacteriophage Mu Gam like protein
NKPELAJD_00045 8.8e-10
NKPELAJD_00047 1.6e-35 K Helix-turn-helix
NKPELAJD_00049 2.2e-105 D Cellulose biosynthesis protein BcsQ
NKPELAJD_00051 5.8e-22
NKPELAJD_00052 3.2e-15
NKPELAJD_00053 6.3e-74 S Pfam:DUF867
NKPELAJD_00054 8.9e-49 S Protein of unknown function (DUF3800)
NKPELAJD_00055 2.3e-90 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
NKPELAJD_00056 6.2e-54 S Bacteriophage holin family
NKPELAJD_00058 9.6e-161 sidC L Phage minor structural protein
NKPELAJD_00059 4.4e-183 yaaC S YaaC-like Protein
NKPELAJD_00060 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NKPELAJD_00061 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NKPELAJD_00062 1.3e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NKPELAJD_00063 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NKPELAJD_00064 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NKPELAJD_00065 6.8e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NKPELAJD_00066 1.3e-09
NKPELAJD_00067 4.1e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NKPELAJD_00068 4.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NKPELAJD_00069 3.8e-211 yaaH M Glycoside Hydrolase Family
NKPELAJD_00070 2.2e-99 yaaI Q COG1335 Amidases related to nicotinamidase
NKPELAJD_00071 7.8e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NKPELAJD_00072 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKPELAJD_00073 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NKPELAJD_00074 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NKPELAJD_00075 3.6e-32 yaaL S Protein of unknown function (DUF2508)
NKPELAJD_00076 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
NKPELAJD_00079 1.6e-08
NKPELAJD_00082 2.2e-54 L COG2963 Transposase and inactivated derivatives
NKPELAJD_00083 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
NKPELAJD_00084 1.3e-07
NKPELAJD_00087 2e-08
NKPELAJD_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
NKPELAJD_00095 7.8e-08
NKPELAJD_00096 3.9e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NKPELAJD_00097 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NKPELAJD_00098 7.1e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NKPELAJD_00099 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NKPELAJD_00100 3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NKPELAJD_00101 0.0 ydiF S ABC transporter
NKPELAJD_00102 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NKPELAJD_00103 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NKPELAJD_00104 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NKPELAJD_00105 3.9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKPELAJD_00106 1.7e-27 ydiK S Domain of unknown function (DUF4305)
NKPELAJD_00107 2.5e-127 ydiL S CAAX protease self-immunity
NKPELAJD_00108 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NKPELAJD_00109 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NKPELAJD_00110 9.1e-14
NKPELAJD_00111 7.2e-167 2.1.1.72 L DNA methylase
NKPELAJD_00112 1.2e-145 3.1.21.5 KL Type III restriction enzyme res subunit
NKPELAJD_00113 7.6e-151 ydjC S Abhydrolase domain containing 18
NKPELAJD_00114 0.0 K NB-ARC domain
NKPELAJD_00115 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
NKPELAJD_00116 1.3e-249 gutA G MFS/sugar transport protein
NKPELAJD_00117 2.6e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NKPELAJD_00118 2.3e-29 yjdJ S Domain of unknown function (DUF4306)
NKPELAJD_00119 3.3e-113 pspA KT Phage shock protein A
NKPELAJD_00120 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKPELAJD_00121 2.6e-119 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NKPELAJD_00122 3.1e-144 ydjI S virion core protein (lumpy skin disease virus)
NKPELAJD_00123 0.0 yrhL I Acyltransferase family
NKPELAJD_00124 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
NKPELAJD_00125 2.2e-54 L COG2963 Transposase and inactivated derivatives
NKPELAJD_00126 1.2e-147 rsiV S Protein of unknown function (DUF3298)
NKPELAJD_00127 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NKPELAJD_00128 1.3e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NKPELAJD_00129 4.2e-62 ydjM M Lytic transglycolase
NKPELAJD_00130 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
NKPELAJD_00132 7.2e-35 ydjO S Cold-inducible protein YdjO
NKPELAJD_00133 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NKPELAJD_00134 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NKPELAJD_00135 1.7e-151 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKPELAJD_00136 4.6e-177 yeaC S COG0714 MoxR-like ATPases
NKPELAJD_00137 4.4e-214 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NKPELAJD_00138 0.0 yebA E COG1305 Transglutaminase-like enzymes
NKPELAJD_00139 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NKPELAJD_00140 1e-187 2.7.7.49 L DNA polymerase
NKPELAJD_00141 3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NKPELAJD_00142 1.6e-247 S Domain of unknown function (DUF4179)
NKPELAJD_00143 1.8e-208 pbuG S permease
NKPELAJD_00144 1.5e-125 yebC M Membrane
NKPELAJD_00146 3.4e-92 yebE S UPF0316 protein
NKPELAJD_00147 6.1e-28 yebG S NETI protein
NKPELAJD_00148 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NKPELAJD_00149 2.3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NKPELAJD_00150 3.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NKPELAJD_00151 8.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NKPELAJD_00152 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKPELAJD_00153 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKPELAJD_00154 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKPELAJD_00155 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NKPELAJD_00156 6.6e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NKPELAJD_00157 2.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NKPELAJD_00158 4.6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NKPELAJD_00159 2.4e-234 purD 6.3.4.13 F Belongs to the GARS family
NKPELAJD_00160 1.2e-25 S Protein of unknown function (DUF2892)
NKPELAJD_00161 0.0 yerA 3.5.4.2 F adenine deaminase
NKPELAJD_00162 4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
NKPELAJD_00163 2.4e-50 yerC S protein conserved in bacteria
NKPELAJD_00164 2.3e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NKPELAJD_00165 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NKPELAJD_00166 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NKPELAJD_00167 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NKPELAJD_00168 1.4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
NKPELAJD_00169 1.1e-194 yerI S homoserine kinase type II (protein kinase fold)
NKPELAJD_00170 4.3e-121 sapB S MgtC SapB transporter
NKPELAJD_00171 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKPELAJD_00172 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKPELAJD_00173 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NKPELAJD_00174 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKPELAJD_00175 7.6e-152 yerO K Transcriptional regulator
NKPELAJD_00176 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NKPELAJD_00177 6.2e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NKPELAJD_00178 4.1e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKPELAJD_00179 2e-14 L Recombinase zinc beta ribbon domain
NKPELAJD_00180 0.0 K SIR2-like domain
NKPELAJD_00181 1.5e-41 S Immunity protein 22
NKPELAJD_00182 8.2e-76 S Protein of unknown function, DUF600
NKPELAJD_00183 4e-57 S Protein of unknown function, DUF600
NKPELAJD_00184 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
NKPELAJD_00185 9.4e-127 yeeN K transcriptional regulatory protein
NKPELAJD_00186 2.4e-108 aadK G Streptomycin adenylyltransferase
NKPELAJD_00187 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
NKPELAJD_00188 3.3e-45 cotJB S CotJB protein
NKPELAJD_00189 8.9e-104 cotJC P Spore Coat
NKPELAJD_00190 7.5e-97 yesJ K Acetyltransferase (GNAT) family
NKPELAJD_00192 1.1e-121 yetF S membrane
NKPELAJD_00193 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NKPELAJD_00194 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKPELAJD_00195 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKPELAJD_00196 7.6e-138 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
NKPELAJD_00197 1.1e-110 cysT O COG0555 ABC-type sulfate transport system, permease component
NKPELAJD_00198 1e-103 cysW P COG4208 ABC-type sulfate transport system, permease component
NKPELAJD_00199 4.5e-133 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NKPELAJD_00200 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
NKPELAJD_00201 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
NKPELAJD_00202 8.2e-106 yetJ S Belongs to the BI1 family
NKPELAJD_00204 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_00205 6.9e-209 yetM CH FAD binding domain
NKPELAJD_00206 8.3e-196 yetN S Protein of unknown function (DUF3900)
NKPELAJD_00207 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NKPELAJD_00209 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NKPELAJD_00210 2.7e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
NKPELAJD_00211 2.1e-171 yfnG 4.2.1.45 M dehydratase
NKPELAJD_00212 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
NKPELAJD_00213 1.9e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NKPELAJD_00214 1.6e-187 yfnD M Nucleotide-diphospho-sugar transferase
NKPELAJD_00215 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
NKPELAJD_00216 7.8e-247 yfnA E amino acid
NKPELAJD_00217 5.9e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKPELAJD_00218 9.8e-115 yfmS NT chemotaxis protein
NKPELAJD_00219 9.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
NKPELAJD_00220 3.2e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKPELAJD_00221 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKPELAJD_00222 1.8e-69 yfmP K transcriptional
NKPELAJD_00223 2.1e-208 yfmO EGP Major facilitator Superfamily
NKPELAJD_00224 4.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKPELAJD_00225 1.1e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NKPELAJD_00226 3.7e-65 yfmK 2.3.1.128 K acetyltransferase
NKPELAJD_00227 3.2e-189 yfmJ S N-terminal domain of oxidoreductase
NKPELAJD_00228 2.9e-24 S Protein of unknown function (DUF3212)
NKPELAJD_00229 1.3e-57 yflT S Heat induced stress protein YflT
NKPELAJD_00230 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NKPELAJD_00231 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
NKPELAJD_00232 8.3e-35 Q PFAM Collagen triple helix
NKPELAJD_00233 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
NKPELAJD_00234 1.1e-273 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NKPELAJD_00235 1.8e-119 citT T response regulator
NKPELAJD_00236 9.2e-178 yflP S Tripartite tricarboxylate transporter family receptor
NKPELAJD_00237 3.8e-227 citM C Citrate transporter
NKPELAJD_00238 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NKPELAJD_00239 2.7e-218 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NKPELAJD_00240 1.7e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NKPELAJD_00241 4.4e-123 yflK S protein conserved in bacteria
NKPELAJD_00242 1.5e-14 yflJ S Protein of unknown function (DUF2639)
NKPELAJD_00243 7e-19 yflI
NKPELAJD_00244 3.1e-50 yflH S Protein of unknown function (DUF3243)
NKPELAJD_00245 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
NKPELAJD_00246 2.5e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NKPELAJD_00247 3.1e-72 yfmQ S Uncharacterised protein from bacillus cereus group
NKPELAJD_00248 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NKPELAJD_00249 7.8e-64 yhdN S Domain of unknown function (DUF1992)
NKPELAJD_00250 5.4e-77 cotP O Belongs to the small heat shock protein (HSP20) family
NKPELAJD_00251 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
NKPELAJD_00252 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
NKPELAJD_00253 1.2e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKPELAJD_00254 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NKPELAJD_00255 2.6e-129 treR K transcriptional
NKPELAJD_00256 1.2e-123 yfkO C nitroreductase
NKPELAJD_00257 4.2e-125 yibF S YibE/F-like protein
NKPELAJD_00258 4.1e-201 yibE S YibE/F-like protein
NKPELAJD_00259 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NKPELAJD_00260 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
NKPELAJD_00261 6.4e-185 K helix_turn _helix lactose operon repressor
NKPELAJD_00262 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NKPELAJD_00263 9.9e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NKPELAJD_00264 8.2e-189 ydiM EGP Major facilitator Superfamily
NKPELAJD_00265 2.7e-29 yfkK S Belongs to the UPF0435 family
NKPELAJD_00266 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKPELAJD_00267 2e-52 yfkI S gas vesicle protein
NKPELAJD_00268 6.8e-145 yihY S Belongs to the UPF0761 family
NKPELAJD_00270 3.8e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NKPELAJD_00271 1.3e-185 cax P COG0387 Ca2 H antiporter
NKPELAJD_00272 2.5e-144 yfkD S YfkD-like protein
NKPELAJD_00273 1.2e-146 yfkC M Mechanosensitive ion channel
NKPELAJD_00274 3e-220 yfkA S YfkB-like domain
NKPELAJD_00275 4.9e-27 yfjT
NKPELAJD_00276 4.5e-154 pdaA G deacetylase
NKPELAJD_00277 1.5e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NKPELAJD_00278 3.9e-31
NKPELAJD_00279 3.8e-184 corA P Mediates influx of magnesium ions
NKPELAJD_00280 2e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NKPELAJD_00281 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKPELAJD_00282 1.7e-50 S YfzA-like protein
NKPELAJD_00283 4.6e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKPELAJD_00284 1.4e-92 yfjM S Psort location Cytoplasmic, score
NKPELAJD_00285 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKPELAJD_00286 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKPELAJD_00287 2.6e-214 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKPELAJD_00288 5.4e-256 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKPELAJD_00289 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NKPELAJD_00290 4.2e-15 sspH S Belongs to the SspH family
NKPELAJD_00291 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NKPELAJD_00292 1.2e-132 glvR F Helix-turn-helix domain, rpiR family
NKPELAJD_00293 2.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKPELAJD_00294 0.0 yfiB3 V ABC transporter
NKPELAJD_00295 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NKPELAJD_00296 7e-63 mhqP S DoxX
NKPELAJD_00297 2.6e-160 yfiE 1.13.11.2 S glyoxalase
NKPELAJD_00298 3.8e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NKPELAJD_00299 1.7e-96 padR K transcriptional
NKPELAJD_00300 4.6e-111 1.6.5.2 S NADPH-dependent FMN reductase
NKPELAJD_00301 1.7e-183 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NKPELAJD_00302 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
NKPELAJD_00303 1.5e-45 yrdF K ribonuclease inhibitor
NKPELAJD_00304 1.4e-98 yfiT S Belongs to the metal hydrolase YfiT family
NKPELAJD_00305 2.3e-290 yfiU EGP Major facilitator Superfamily
NKPELAJD_00306 5.6e-83 yfiV K transcriptional
NKPELAJD_00307 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NKPELAJD_00308 5.1e-167 yfhB 5.3.3.17 S PhzF family
NKPELAJD_00309 7.4e-106 yfhC C nitroreductase
NKPELAJD_00310 8e-25 yfhD S YfhD-like protein
NKPELAJD_00312 2.6e-166 yfhF S nucleoside-diphosphate sugar epimerase
NKPELAJD_00313 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NKPELAJD_00314 8.8e-53 yfhH S Protein of unknown function (DUF1811)
NKPELAJD_00315 2.6e-206 yfhI EGP Major facilitator Superfamily
NKPELAJD_00317 4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NKPELAJD_00318 2.2e-44 yfhJ S WVELL protein
NKPELAJD_00319 1.6e-94 batE T Bacterial SH3 domain homologues
NKPELAJD_00320 2.6e-34 yfhL S SdpI/YhfL protein family
NKPELAJD_00321 6.3e-170 yfhM S Alpha/beta hydrolase family
NKPELAJD_00322 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKPELAJD_00323 0.0 yfhO S Bacterial membrane protein YfhO
NKPELAJD_00324 1e-184 yfhP S membrane-bound metal-dependent
NKPELAJD_00325 1.8e-209 mutY L A G-specific
NKPELAJD_00326 8.2e-37 yfhS
NKPELAJD_00327 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_00329 1.5e-37 ygaB S YgaB-like protein
NKPELAJD_00330 2.2e-104 ygaC J Belongs to the UPF0374 family
NKPELAJD_00331 4.2e-306 ygaD V ABC transporter
NKPELAJD_00332 3.2e-179 ygaE S Membrane
NKPELAJD_00333 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NKPELAJD_00334 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
NKPELAJD_00335 1.8e-80 perR P Belongs to the Fur family
NKPELAJD_00336 1.5e-56 ygzB S UPF0295 protein
NKPELAJD_00337 3.7e-165 ygxA S Nucleotidyltransferase-like
NKPELAJD_00338 7.1e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
NKPELAJD_00339 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NKPELAJD_00340 1.7e-75 gerD
NKPELAJD_00341 1.5e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NKPELAJD_00342 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKPELAJD_00343 1.7e-78 ybaK S Protein of unknown function (DUF2521)
NKPELAJD_00344 5.9e-85 yizA S Damage-inducible protein DinB
NKPELAJD_00345 3.1e-144 ybaJ Q Methyltransferase domain
NKPELAJD_00346 3.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NKPELAJD_00347 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NKPELAJD_00348 1.8e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NKPELAJD_00349 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKPELAJD_00350 2.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKPELAJD_00351 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKPELAJD_00352 4.7e-58 rplQ J Ribosomal protein L17
NKPELAJD_00353 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKPELAJD_00354 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NKPELAJD_00355 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NKPELAJD_00356 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NKPELAJD_00357 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NKPELAJD_00358 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
NKPELAJD_00359 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NKPELAJD_00360 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NKPELAJD_00361 4.1e-72 rplO J binds to the 23S rRNA
NKPELAJD_00362 1.9e-23 rpmD J Ribosomal protein L30
NKPELAJD_00363 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NKPELAJD_00364 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NKPELAJD_00365 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NKPELAJD_00366 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NKPELAJD_00367 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKPELAJD_00368 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NKPELAJD_00369 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NKPELAJD_00370 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NKPELAJD_00371 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NKPELAJD_00372 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NKPELAJD_00373 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NKPELAJD_00374 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NKPELAJD_00375 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NKPELAJD_00376 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NKPELAJD_00377 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NKPELAJD_00378 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NKPELAJD_00379 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
NKPELAJD_00380 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NKPELAJD_00381 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NKPELAJD_00382 1.5e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NKPELAJD_00383 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NKPELAJD_00384 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NKPELAJD_00385 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NKPELAJD_00386 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NKPELAJD_00387 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NKPELAJD_00388 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKPELAJD_00389 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKPELAJD_00390 9.7e-109 rsmC 2.1.1.172 J Methyltransferase
NKPELAJD_00391 3.6e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NKPELAJD_00392 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NKPELAJD_00393 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NKPELAJD_00394 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NKPELAJD_00395 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NKPELAJD_00396 8.9e-116 sigH K Belongs to the sigma-70 factor family
NKPELAJD_00397 2.8e-88 yacP S RNA-binding protein containing a PIN domain
NKPELAJD_00398 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKPELAJD_00399 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NKPELAJD_00400 3.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NKPELAJD_00401 1e-116 cysE 2.3.1.30 E Serine acetyltransferase
NKPELAJD_00402 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NKPELAJD_00403 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NKPELAJD_00404 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NKPELAJD_00405 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NKPELAJD_00406 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NKPELAJD_00407 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NKPELAJD_00408 0.0 clpC O Belongs to the ClpA ClpB family
NKPELAJD_00409 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NKPELAJD_00410 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NKPELAJD_00411 7.5e-77 ctsR K Belongs to the CtsR family
NKPELAJD_00412 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKPELAJD_00413 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKPELAJD_00414 8.1e-38 yaaB S Domain of unknown function (DUF370)
NKPELAJD_00415 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NKPELAJD_00416 2.4e-33 yaaA S S4 domain
NKPELAJD_00417 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NKPELAJD_00418 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NKPELAJD_00419 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NKPELAJD_00420 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NKPELAJD_00421 5.5e-110 jag S single-stranded nucleic acid binding R3H
NKPELAJD_00422 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NKPELAJD_00423 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NKPELAJD_00424 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NKPELAJD_00425 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NKPELAJD_00426 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
NKPELAJD_00427 7.9e-149 spo0J K Belongs to the ParB family
NKPELAJD_00428 6.2e-111 yyaC S Sporulation protein YyaC
NKPELAJD_00429 9e-84 4.2.1.103 K FR47-like protein
NKPELAJD_00430 2.4e-176 yyaD S Membrane
NKPELAJD_00431 2.3e-33 yyzM S protein conserved in bacteria
NKPELAJD_00432 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKPELAJD_00433 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NKPELAJD_00434 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NKPELAJD_00435 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NKPELAJD_00436 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NKPELAJD_00437 3.9e-107 adaA 3.2.2.21 K Transcriptional regulator
NKPELAJD_00438 1.8e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NKPELAJD_00439 1.6e-145 xth 3.1.11.2 L exodeoxyribonuclease III
NKPELAJD_00440 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NKPELAJD_00441 5.8e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKPELAJD_00442 5.2e-248 ydjK G Sugar (and other) transporter
NKPELAJD_00443 1.2e-163 yyaK S CAAX protease self-immunity
NKPELAJD_00444 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NKPELAJD_00445 4.6e-100 yvdD 3.2.2.10 S Belongs to the LOG family
NKPELAJD_00446 1.1e-30 yvdC S MazG nucleotide pyrophosphohydrolase domain
NKPELAJD_00447 1.7e-163 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NKPELAJD_00448 1.6e-77 S Protein of unknown function with HXXEE motif
NKPELAJD_00449 4.3e-31 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NKPELAJD_00450 1.8e-130 ydfC EG EamA-like transporter family
NKPELAJD_00451 1.8e-249 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKPELAJD_00452 9.9e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NKPELAJD_00453 4.5e-166 K Transcriptional regulator
NKPELAJD_00454 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
NKPELAJD_00455 5.7e-163 eaeH M Domain of Unknown Function (DUF1259)
NKPELAJD_00456 3.5e-76 yjcF S Acetyltransferase (GNAT) domain
NKPELAJD_00457 2.5e-77 yybA 2.3.1.57 K transcriptional
NKPELAJD_00458 9.3e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NKPELAJD_00459 9.2e-69 ydgJ K Winged helix DNA-binding domain
NKPELAJD_00460 5.6e-115 drgA C nitroreductase
NKPELAJD_00461 1.3e-55 ypaA S Protein of unknown function (DUF1304)
NKPELAJD_00462 1.6e-100 E LysE type translocator
NKPELAJD_00463 8.4e-162 yfiE K LysR substrate binding domain
NKPELAJD_00464 8.9e-162 G Major Facilitator Superfamily
NKPELAJD_00465 2.7e-75 dinB S PFAM DinB family protein
NKPELAJD_00466 1.8e-116 K FCD domain
NKPELAJD_00467 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
NKPELAJD_00468 7.7e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NKPELAJD_00469 4.4e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NKPELAJD_00470 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NKPELAJD_00471 8.2e-66 ydeP3 K Transcriptional regulator
NKPELAJD_00472 1.1e-83 cotF M Spore coat protein
NKPELAJD_00474 1.6e-158 yybS S membrane
NKPELAJD_00475 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NKPELAJD_00476 1.4e-72 rplI J binds to the 23S rRNA
NKPELAJD_00477 3.8e-122 KLT COG0515 Serine threonine protein kinase
NKPELAJD_00478 1.7e-122 S GlcNAc-PI de-N-acetylase
NKPELAJD_00479 1.9e-242 M Glycosyltransferase Family 4
NKPELAJD_00480 7.7e-235 S Carbamoyl-phosphate synthase L chain, ATP binding domain
NKPELAJD_00481 5.1e-206 S Ecdysteroid kinase
NKPELAJD_00482 4.6e-241 M Glycosyltransferase Family 4
NKPELAJD_00483 3.5e-17 yycC K YycC-like protein
NKPELAJD_00485 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NKPELAJD_00486 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NKPELAJD_00487 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKPELAJD_00488 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NKPELAJD_00492 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_00493 0.0 vicK 2.7.13.3 T Histidine kinase
NKPELAJD_00494 1e-259 yycH S protein conserved in bacteria
NKPELAJD_00495 6.4e-151 yycI S protein conserved in bacteria
NKPELAJD_00496 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NKPELAJD_00497 1.3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKPELAJD_00498 4.7e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_00499 1.1e-251 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NKPELAJD_00500 4.9e-190 2.7.7.73, 2.7.7.80 H ThiF family
NKPELAJD_00501 1e-259
NKPELAJD_00502 3.4e-198 S Major Facilitator Superfamily
NKPELAJD_00503 5.7e-305 S ABC transporter
NKPELAJD_00504 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
NKPELAJD_00505 3.4e-261 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NKPELAJD_00506 2.2e-42 sdpR K transcriptional
NKPELAJD_00507 4.2e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NKPELAJD_00508 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NKPELAJD_00509 2.6e-258 rocE E amino acid
NKPELAJD_00510 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NKPELAJD_00511 7.6e-200 S Histidine kinase
NKPELAJD_00513 3.7e-87 yycN 2.3.1.128 K Acetyltransferase
NKPELAJD_00514 2.1e-185 C oxidoreductases (related to aryl-alcohol dehydrogenases)
NKPELAJD_00515 2.4e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NKPELAJD_00516 2.9e-218 yycP
NKPELAJD_00518 7.9e-08 S YyzF-like protein
NKPELAJD_00519 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NKPELAJD_00520 9.7e-115
NKPELAJD_00521 5.5e-247 L Uncharacterized conserved protein (DUF2075)
NKPELAJD_00522 6.1e-180 S Fusaric acid resistance protein-like
NKPELAJD_00523 7.2e-189 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NKPELAJD_00524 3.7e-95 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NKPELAJD_00525 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NKPELAJD_00526 1.6e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NKPELAJD_00527 1.1e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NKPELAJD_00528 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NKPELAJD_00529 1.4e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
NKPELAJD_00530 2.7e-230 XK27_00240 S Fic/DOC family
NKPELAJD_00531 2.3e-287 ahpF O Alkyl hydroperoxide reductase
NKPELAJD_00532 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NKPELAJD_00533 2.4e-127 E Ring-cleavage extradiol dioxygenase
NKPELAJD_00534 7.6e-74 yxaI S membrane protein domain
NKPELAJD_00535 2e-203 EGP Major facilitator Superfamily
NKPELAJD_00536 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
NKPELAJD_00537 1.7e-59 S Family of unknown function (DUF5391)
NKPELAJD_00538 1.2e-140 S PQQ-like domain
NKPELAJD_00539 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NKPELAJD_00540 2.1e-216 yxbF K Bacterial regulatory proteins, tetR family
NKPELAJD_00541 2.6e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NKPELAJD_00542 1.7e-199 desK 2.7.13.3 T Histidine kinase
NKPELAJD_00543 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKPELAJD_00544 3.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
NKPELAJD_00546 0.0 htpG O Molecular chaperone. Has ATPase activity
NKPELAJD_00547 6.7e-246 csbC EGP Major facilitator Superfamily
NKPELAJD_00548 4.9e-176 iolS C Aldo keto reductase
NKPELAJD_00549 6.8e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
NKPELAJD_00550 5.1e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKPELAJD_00551 2.2e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NKPELAJD_00552 4.4e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NKPELAJD_00553 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NKPELAJD_00554 3.6e-176 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NKPELAJD_00555 3.9e-232 iolF EGP Major facilitator Superfamily
NKPELAJD_00556 5.6e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NKPELAJD_00557 1.1e-166 iolH G Xylose isomerase-like TIM barrel
NKPELAJD_00558 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NKPELAJD_00559 1.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NKPELAJD_00560 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_00561 1.6e-174 T PhoQ Sensor
NKPELAJD_00562 5.5e-141 yxdL V ABC transporter, ATP-binding protein
NKPELAJD_00563 0.0 yxdM V ABC transporter (permease)
NKPELAJD_00564 1.3e-57 yxeA S Protein of unknown function (DUF1093)
NKPELAJD_00565 3.9e-176 fhuD P Periplasmic binding protein
NKPELAJD_00566 6e-35
NKPELAJD_00567 8.4e-23 yxeD
NKPELAJD_00568 6.4e-13 yxeE
NKPELAJD_00571 4e-150 yidA S hydrolases of the HAD superfamily
NKPELAJD_00572 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NKPELAJD_00573 1.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NKPELAJD_00574 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKPELAJD_00575 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NKPELAJD_00576 2.9e-252 lysP E amino acid
NKPELAJD_00577 4.5e-177 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NKPELAJD_00578 8.8e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NKPELAJD_00579 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NKPELAJD_00580 1.5e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
NKPELAJD_00581 3.8e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NKPELAJD_00582 2.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NKPELAJD_00583 2.8e-64 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NKPELAJD_00584 0.0 L HKD family nuclease
NKPELAJD_00585 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKPELAJD_00586 2.7e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NKPELAJD_00587 6.3e-73 yxiE T Belongs to the universal stress protein A family
NKPELAJD_00588 1.2e-147 yxxF EG EamA-like transporter family
NKPELAJD_00589 1.3e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
NKPELAJD_00590 1e-18 wapA M COG3209 Rhs family protein
NKPELAJD_00591 0.0 wapA M COG3209 Rhs family protein
NKPELAJD_00592 5.9e-32
NKPELAJD_00593 4e-36 yxiG
NKPELAJD_00596 3.4e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NKPELAJD_00597 2.9e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
NKPELAJD_00598 7.7e-149 licT K transcriptional antiterminator
NKPELAJD_00599 1.5e-143 exoK GH16 M licheninase activity
NKPELAJD_00600 2.8e-222 citH C Citrate transporter
NKPELAJD_00601 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NKPELAJD_00602 1.4e-50 yxiS
NKPELAJD_00603 7.8e-75 T Domain of unknown function (DUF4163)
NKPELAJD_00604 3.8e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKPELAJD_00605 2.2e-162 rlmA 2.1.1.187 Q Methyltransferase domain
NKPELAJD_00606 2.3e-198 yxjG 2.1.1.14 E Methionine synthase
NKPELAJD_00607 1.2e-69 yxjI S LURP-one-related
NKPELAJD_00610 4.7e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NKPELAJD_00611 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NKPELAJD_00612 3.8e-87 yxkC S Domain of unknown function (DUF4352)
NKPELAJD_00614 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKPELAJD_00615 6.1e-168 lrp QT PucR C-terminal helix-turn-helix domain
NKPELAJD_00616 2.6e-205 msmK P Belongs to the ABC transporter superfamily
NKPELAJD_00617 7.1e-158 yxkH G Polysaccharide deacetylase
NKPELAJD_00618 1.5e-215 cimH C COG3493 Na citrate symporter
NKPELAJD_00619 1.2e-32 cydA 1.10.3.14 C oxidase, subunit
NKPELAJD_00620 5.7e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NKPELAJD_00621 2.4e-311 cydD V ATP-binding
NKPELAJD_00622 1.3e-291 cydD V ATP-binding protein
NKPELAJD_00623 2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NKPELAJD_00624 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NKPELAJD_00625 1.9e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NKPELAJD_00626 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NKPELAJD_00627 4.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NKPELAJD_00628 3.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NKPELAJD_00629 1.9e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NKPELAJD_00630 1.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NKPELAJD_00631 3.2e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKPELAJD_00632 9.1e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NKPELAJD_00633 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NKPELAJD_00634 2.2e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NKPELAJD_00635 4.5e-58 arsR K transcriptional
NKPELAJD_00636 4e-167 cbrA3 P Periplasmic binding protein
NKPELAJD_00637 1.3e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_00638 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_00639 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NKPELAJD_00640 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NKPELAJD_00641 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NKPELAJD_00642 5.3e-248 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKPELAJD_00643 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NKPELAJD_00644 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NKPELAJD_00645 1.3e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NKPELAJD_00646 1.8e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NKPELAJD_00647 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_00648 3.7e-229 dltB M membrane protein involved in D-alanine export
NKPELAJD_00649 5.5e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_00650 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
NKPELAJD_00651 1.7e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NKPELAJD_00652 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
NKPELAJD_00653 2.6e-163 gspA M General stress
NKPELAJD_00654 3.3e-266 epr 3.4.21.62 O Belongs to the peptidase S8 family
NKPELAJD_00655 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKPELAJD_00656 9e-68 ywbC 4.4.1.5 E glyoxalase
NKPELAJD_00657 8.8e-223 ywbD 2.1.1.191 J Methyltransferase
NKPELAJD_00658 3.3e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
NKPELAJD_00659 4.9e-142 mta K transcriptional
NKPELAJD_00660 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
NKPELAJD_00661 2.2e-54 L COG2963 Transposase and inactivated derivatives
NKPELAJD_00662 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NKPELAJD_00664 2.2e-100
NKPELAJD_00667 1e-95 V ATPases associated with a variety of cellular activities
NKPELAJD_00668 4.1e-108 ywbG M effector of murein hydrolase
NKPELAJD_00669 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NKPELAJD_00670 8.2e-152 ywbI K Transcriptional regulator
NKPELAJD_00671 4.3e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NKPELAJD_00672 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NKPELAJD_00673 1.1e-242 ywbN P Dyp-type peroxidase family protein
NKPELAJD_00674 1.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NKPELAJD_00675 6.3e-133 S Streptomycin biosynthesis protein StrF
NKPELAJD_00676 4.3e-129 H Methionine biosynthesis protein MetW
NKPELAJD_00678 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
NKPELAJD_00679 3.5e-62 gtcA S GtrA-like protein
NKPELAJD_00680 8.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NKPELAJD_00681 3.5e-296 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NKPELAJD_00682 8.4e-27 ywzA S membrane
NKPELAJD_00683 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NKPELAJD_00684 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NKPELAJD_00685 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NKPELAJD_00686 5.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NKPELAJD_00687 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
NKPELAJD_00688 1.5e-78 ysnE K acetyltransferase
NKPELAJD_00689 2.9e-213 rodA D Belongs to the SEDS family
NKPELAJD_00690 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NKPELAJD_00691 8.9e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKPELAJD_00692 0.0 vpr O Belongs to the peptidase S8 family
NKPELAJD_00694 8.3e-151 sacT K transcriptional antiterminator
NKPELAJD_00695 6.2e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKPELAJD_00696 9.5e-288 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
NKPELAJD_00697 9.7e-20 ywdA
NKPELAJD_00698 1.3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NKPELAJD_00699 6.3e-57 pex K Transcriptional regulator PadR-like family
NKPELAJD_00700 7.6e-88 ywdD
NKPELAJD_00702 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
NKPELAJD_00703 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NKPELAJD_00704 4.7e-41 ywdI S Family of unknown function (DUF5327)
NKPELAJD_00705 3.7e-230 ywdJ F Xanthine uracil
NKPELAJD_00706 1.6e-45 ywdK S small membrane protein
NKPELAJD_00707 1.7e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NKPELAJD_00708 3.4e-143 spsA M Spore Coat
NKPELAJD_00709 1.7e-276 spsB M Capsule polysaccharide biosynthesis protein
NKPELAJD_00710 3.3e-222 spsC E Belongs to the DegT DnrJ EryC1 family
NKPELAJD_00711 1e-159 spsD 2.3.1.210 K Spore Coat
NKPELAJD_00712 2.9e-215 spsE 2.5.1.56 M acid synthase
NKPELAJD_00713 1.1e-133 spsF M Spore Coat
NKPELAJD_00714 9.9e-183 spsG M Spore Coat
NKPELAJD_00715 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NKPELAJD_00716 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NKPELAJD_00717 8.1e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NKPELAJD_00718 5.5e-88 spsL 5.1.3.13 M Spore Coat
NKPELAJD_00719 3.2e-59
NKPELAJD_00720 9.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NKPELAJD_00721 3.9e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NKPELAJD_00722 0.0 rocB E arginine degradation protein
NKPELAJD_00723 1.4e-259 lysP E amino acid
NKPELAJD_00724 1.1e-196 tcaB EGP Major facilitator Superfamily
NKPELAJD_00725 4.1e-223 ywfA EGP Major facilitator Superfamily
NKPELAJD_00726 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NKPELAJD_00727 3.4e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NKPELAJD_00728 1.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_00729 2.2e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NKPELAJD_00730 4.7e-208 bacE EGP Major facilitator Superfamily
NKPELAJD_00731 1.9e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
NKPELAJD_00732 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
NKPELAJD_00733 1.1e-146 ywfI C May function as heme-dependent peroxidase
NKPELAJD_00734 1.1e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NKPELAJD_00735 1.1e-157 MA20_14895 S Conserved hypothetical protein 698
NKPELAJD_00736 3e-162 cysL K Transcriptional regulator
NKPELAJD_00737 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NKPELAJD_00739 1.4e-186
NKPELAJD_00742 4.5e-169 yhcI S ABC transporter (permease)
NKPELAJD_00743 1.6e-166 V ABC transporter, ATP-binding protein
NKPELAJD_00744 1.5e-92 S membrane
NKPELAJD_00745 4.1e-50 padR K PadR family transcriptional regulator
NKPELAJD_00746 6.6e-110 rsfA_1
NKPELAJD_00747 6.9e-36 ywzC S Belongs to the UPF0741 family
NKPELAJD_00748 7.9e-257 ywfO S COG1078 HD superfamily phosphohydrolases
NKPELAJD_00749 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
NKPELAJD_00750 1.3e-246 yhdG_1 E C-terminus of AA_permease
NKPELAJD_00751 5.2e-69 ywhA K Transcriptional regulator
NKPELAJD_00752 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NKPELAJD_00753 1.2e-117 ywhC S Peptidase family M50
NKPELAJD_00754 1.4e-95 ywhD S YwhD family
NKPELAJD_00755 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NKPELAJD_00756 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NKPELAJD_00757 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
NKPELAJD_00760 3.1e-76 CP Membrane
NKPELAJD_00762 1.3e-27 S Domain of unknown function (DUF4177)
NKPELAJD_00763 5e-33
NKPELAJD_00765 1.4e-76 S aspartate phosphatase
NKPELAJD_00766 1.5e-221 ywhK CO amine dehydrogenase activity
NKPELAJD_00767 1.1e-229 ywhL CO amine dehydrogenase activity
NKPELAJD_00769 1.2e-73 ywiB S protein conserved in bacteria
NKPELAJD_00770 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NKPELAJD_00771 5.8e-214 narK P COG2223 Nitrate nitrite transporter
NKPELAJD_00772 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NKPELAJD_00773 1.7e-139 ywiC S YwiC-like protein
NKPELAJD_00774 4.5e-85 arfM T cyclic nucleotide binding
NKPELAJD_00775 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKPELAJD_00776 1.8e-294 narH 1.7.5.1 C Nitrate reductase, beta
NKPELAJD_00777 1.8e-96 narJ 1.7.5.1 C nitrate reductase
NKPELAJD_00778 4.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
NKPELAJD_00779 1.4e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKPELAJD_00780 9.6e-302 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKPELAJD_00781 0.0 ywjA V ABC transporter
NKPELAJD_00782 4.2e-43 ywjC
NKPELAJD_00783 1.2e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NKPELAJD_00784 3.5e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NKPELAJD_00785 0.0 fadF C COG0247 Fe-S oxidoreductase
NKPELAJD_00786 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NKPELAJD_00787 1.7e-93 ywjG S Domain of unknown function (DUF2529)
NKPELAJD_00788 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
NKPELAJD_00789 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NKPELAJD_00790 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NKPELAJD_00791 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKPELAJD_00792 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NKPELAJD_00793 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NKPELAJD_00794 1.1e-32 rpmE J Binds the 23S rRNA
NKPELAJD_00795 1.4e-104 tdk 2.7.1.21 F thymidine kinase
NKPELAJD_00796 0.0 sfcA 1.1.1.38 C malic enzyme
NKPELAJD_00797 3.6e-158 ywkB S Membrane transport protein
NKPELAJD_00798 1.1e-93 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NKPELAJD_00799 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKPELAJD_00800 3.3e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NKPELAJD_00801 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NKPELAJD_00803 4e-60 ywlA S Uncharacterised protein family (UPF0715)
NKPELAJD_00804 1.5e-118 spoIIR S stage II sporulation protein R
NKPELAJD_00805 1e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NKPELAJD_00806 1e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NKPELAJD_00807 9e-85 mntP P Probably functions as a manganese efflux pump
NKPELAJD_00808 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKPELAJD_00809 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NKPELAJD_00810 5.9e-97 ywlG S Belongs to the UPF0340 family
NKPELAJD_00811 3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NKPELAJD_00812 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NKPELAJD_00813 2.1e-61 atpI S ATP synthase
NKPELAJD_00814 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
NKPELAJD_00815 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKPELAJD_00816 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NKPELAJD_00817 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKPELAJD_00818 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NKPELAJD_00819 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NKPELAJD_00820 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NKPELAJD_00821 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NKPELAJD_00822 1.2e-90 ywmA
NKPELAJD_00823 4.8e-32 ywzB S membrane
NKPELAJD_00824 4.8e-134 ywmB S TATA-box binding
NKPELAJD_00825 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKPELAJD_00826 4.3e-189 spoIID D Stage II sporulation protein D
NKPELAJD_00827 2.7e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NKPELAJD_00828 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NKPELAJD_00830 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NKPELAJD_00831 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NKPELAJD_00832 2.8e-93 S response regulator aspartate phosphatase
NKPELAJD_00833 2.1e-82 ywmF S Peptidase M50
NKPELAJD_00834 6.5e-11 csbD K CsbD-like
NKPELAJD_00835 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NKPELAJD_00836 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NKPELAJD_00837 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NKPELAJD_00838 6.1e-67 ywnA K Transcriptional regulator
NKPELAJD_00839 4.5e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NKPELAJD_00840 1.7e-53 ywnC S Family of unknown function (DUF5362)
NKPELAJD_00841 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKPELAJD_00842 1.6e-68 ywnF S Family of unknown function (DUF5392)
NKPELAJD_00843 1.2e-10 ywnC S Family of unknown function (DUF5362)
NKPELAJD_00844 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NKPELAJD_00845 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NKPELAJD_00846 5.1e-72 ywnJ S VanZ like family
NKPELAJD_00847 4.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NKPELAJD_00848 2.4e-209 ftsW D Belongs to the SEDS family
NKPELAJD_00849 2e-58 nrgB K Belongs to the P(II) protein family
NKPELAJD_00850 2.5e-228 amt P Ammonium transporter
NKPELAJD_00851 2.4e-101 phzA Q Isochorismatase family
NKPELAJD_00852 2e-242 ywoD EGP Major facilitator superfamily
NKPELAJD_00853 5e-276 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NKPELAJD_00854 2.4e-212 ywoG EGP Major facilitator Superfamily
NKPELAJD_00855 8.5e-72 ywoH K transcriptional
NKPELAJD_00856 1.8e-44 spoIIID K Stage III sporulation protein D
NKPELAJD_00857 2.7e-180 mbl D Rod shape-determining protein
NKPELAJD_00858 4.7e-127 flhO N flagellar basal body
NKPELAJD_00859 3.3e-144 flhP N flagellar basal body
NKPELAJD_00860 2.9e-201 S aspartate phosphatase
NKPELAJD_00861 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NKPELAJD_00862 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NKPELAJD_00863 3.9e-69 ywpF S YwpF-like protein
NKPELAJD_00864 4e-62 ywpG
NKPELAJD_00865 3.7e-57 ssbB L Single-stranded DNA-binding protein
NKPELAJD_00866 3.7e-137 glcR K DeoR C terminal sensor domain
NKPELAJD_00867 1.1e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NKPELAJD_00868 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NKPELAJD_00869 9.3e-308 ywqB S SWIM zinc finger
NKPELAJD_00870 1.3e-14
NKPELAJD_00871 5.2e-112 ywqC M biosynthesis protein
NKPELAJD_00872 1.5e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NKPELAJD_00873 8.4e-142 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NKPELAJD_00874 1.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKPELAJD_00875 1.4e-152 ywqG S Domain of unknown function (DUF1963)
NKPELAJD_00877 1.1e-21 S Domain of unknown function (DUF5082)
NKPELAJD_00878 4.3e-37 ywqI S Family of unknown function (DUF5344)
NKPELAJD_00879 2.1e-258 ywqJ S Pre-toxin TG
NKPELAJD_00880 1.1e-24
NKPELAJD_00881 1.5e-97 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NKPELAJD_00882 8.4e-88 ywrA P COG2059 Chromate transport protein ChrA
NKPELAJD_00883 4.6e-103 ywrB P Chromate transporter
NKPELAJD_00884 1.1e-83 ywrC K Transcriptional regulator
NKPELAJD_00885 3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NKPELAJD_00887 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NKPELAJD_00888 1e-212 cotH M Spore Coat
NKPELAJD_00889 1.9e-129 cotB
NKPELAJD_00890 4.4e-126 ywrJ
NKPELAJD_00891 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NKPELAJD_00893 9e-167 alsR K LysR substrate binding domain
NKPELAJD_00894 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NKPELAJD_00895 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NKPELAJD_00896 4.8e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
NKPELAJD_00897 5.2e-90 batE T Sh3 type 3 domain protein
NKPELAJD_00898 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NKPELAJD_00899 3.2e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NKPELAJD_00900 6.4e-279 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NKPELAJD_00901 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NKPELAJD_00902 1.1e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NKPELAJD_00903 1.1e-178 rbsR K transcriptional
NKPELAJD_00904 2e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
NKPELAJD_00905 2.8e-191 gerKB E Spore germination protein
NKPELAJD_00906 7.7e-184 gerKA EG Spore germination protein
NKPELAJD_00907 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NKPELAJD_00908 2.3e-70 pgsC S biosynthesis protein
NKPELAJD_00909 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NKPELAJD_00910 1.3e-20 ywtC
NKPELAJD_00911 6.3e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NKPELAJD_00912 4.5e-36 yttA 2.7.13.3 S Pfam Transposase IS66
NKPELAJD_00913 6.5e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NKPELAJD_00914 3.7e-249 ywtG EGP Major facilitator Superfamily
NKPELAJD_00915 1.2e-266 GT2,GT4 J Glycosyl transferase family 2
NKPELAJD_00916 3.2e-214 gerAC S Spore germination protein
NKPELAJD_00917 6.4e-199 gerBB E Spore germination protein
NKPELAJD_00918 1.3e-265 gerBA EG Spore germination protein
NKPELAJD_00919 4.8e-187 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NKPELAJD_00920 5.9e-235 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NKPELAJD_00921 4.2e-217 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NKPELAJD_00922 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NKPELAJD_00923 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NKPELAJD_00924 3.3e-294 M Glycosyltransferase like family 2
NKPELAJD_00925 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NKPELAJD_00926 1.7e-151 tagG GM Transport permease protein
NKPELAJD_00927 2.6e-283 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NKPELAJD_00928 1.2e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NKPELAJD_00929 9.7e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NKPELAJD_00930 1.8e-143 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NKPELAJD_00931 5.9e-49
NKPELAJD_00932 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NKPELAJD_00933 9.3e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKPELAJD_00934 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NKPELAJD_00935 1e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKPELAJD_00936 7.3e-225 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NKPELAJD_00937 6.6e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKPELAJD_00938 2.9e-257 tuaE M Teichuronic acid biosynthesis protein
NKPELAJD_00939 1.6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
NKPELAJD_00940 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
NKPELAJD_00941 5.2e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NKPELAJD_00942 1.6e-118 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NKPELAJD_00943 7.3e-39 yvhJ K Transcriptional regulator
NKPELAJD_00944 2.2e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NKPELAJD_00945 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NKPELAJD_00946 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKPELAJD_00947 3.5e-157 degV S protein conserved in bacteria
NKPELAJD_00948 2.1e-260 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NKPELAJD_00949 1.5e-43 comFB S Late competence development protein ComFB
NKPELAJD_00950 9.1e-78 comFC S Phosphoribosyl transferase domain
NKPELAJD_00951 1.4e-74 yvyF S flagellar protein
NKPELAJD_00952 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
NKPELAJD_00953 8.9e-81 flgN NOU FlgN protein
NKPELAJD_00954 2.8e-274 flgK N flagellar hook-associated protein
NKPELAJD_00955 2.3e-162 flgL N Belongs to the bacterial flagellin family
NKPELAJD_00956 4.4e-79 yviE
NKPELAJD_00957 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NKPELAJD_00958 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NKPELAJD_00959 2e-103 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NKPELAJD_00960 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NKPELAJD_00961 3e-66 fliS N flagellar protein FliS
NKPELAJD_00962 9.1e-11 fliT S bacterial-type flagellum organization
NKPELAJD_00963 6.8e-68
NKPELAJD_00964 4.8e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NKPELAJD_00965 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NKPELAJD_00966 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NKPELAJD_00967 1.6e-149 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NKPELAJD_00968 2.4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
NKPELAJD_00969 1e-122 ftsE D cell division ATP-binding protein FtsE
NKPELAJD_00970 9.2e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NKPELAJD_00971 6.3e-228 ywoF P Right handed beta helix region
NKPELAJD_00972 2.1e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NKPELAJD_00973 1.5e-55 swrA S Swarming motility protein
NKPELAJD_00974 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKPELAJD_00975 3e-227 yvkA EGP Major facilitator Superfamily
NKPELAJD_00976 2.4e-110 yvkB K Transcriptional regulator
NKPELAJD_00977 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NKPELAJD_00978 7.6e-33 csbA S protein conserved in bacteria
NKPELAJD_00979 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NKPELAJD_00980 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NKPELAJD_00981 2.5e-37 yvkN
NKPELAJD_00982 6.1e-49 yvlA
NKPELAJD_00983 3.2e-166 yvlB S Putative adhesin
NKPELAJD_00984 9.6e-26 pspB KT PspC domain
NKPELAJD_00985 3.9e-41 yvlD S Membrane
NKPELAJD_00986 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NKPELAJD_00987 1.8e-104 yxaF K Transcriptional regulator
NKPELAJD_00988 1.1e-133 yvoA K transcriptional
NKPELAJD_00989 2.8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NKPELAJD_00990 2.9e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NKPELAJD_00991 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NKPELAJD_00992 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NKPELAJD_00993 2.4e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NKPELAJD_00994 1.3e-77 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NKPELAJD_00995 1.2e-137 yvpB NU protein conserved in bacteria
NKPELAJD_00996 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NKPELAJD_00997 1.3e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NKPELAJD_00998 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NKPELAJD_00999 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NKPELAJD_01000 1.5e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NKPELAJD_01001 7.6e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NKPELAJD_01002 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NKPELAJD_01003 5.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NKPELAJD_01004 0.0 msbA2 3.6.3.44 V ABC transporter
NKPELAJD_01005 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_01006 3.2e-192 sasA T Histidine kinase
NKPELAJD_01007 5e-276 S COG0457 FOG TPR repeat
NKPELAJD_01008 5e-124 usp CBM50 M protein conserved in bacteria
NKPELAJD_01009 1.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NKPELAJD_01010 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NKPELAJD_01011 1.1e-166 rapZ S Displays ATPase and GTPase activities
NKPELAJD_01012 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NKPELAJD_01013 3.1e-170 whiA K May be required for sporulation
NKPELAJD_01014 4.7e-36 crh G Phosphocarrier protein Chr
NKPELAJD_01015 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NKPELAJD_01016 1.6e-79 M Ribonuclease
NKPELAJD_01017 8.6e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKPELAJD_01018 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NKPELAJD_01019 3.9e-274 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NKPELAJD_01020 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NKPELAJD_01021 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NKPELAJD_01022 6.8e-251 EGP Sugar (and other) transporter
NKPELAJD_01023 7.1e-214 yraM S PrpF protein
NKPELAJD_01024 6.7e-164 yraN K Transcriptional regulator
NKPELAJD_01025 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NKPELAJD_01026 1.3e-184 scrR K transcriptional
NKPELAJD_01027 2.8e-219 rafB P LacY proton/sugar symporter
NKPELAJD_01028 4.4e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
NKPELAJD_01030 3.1e-34
NKPELAJD_01031 2.6e-211 I Pfam Lipase (class 3)
NKPELAJD_01032 9.8e-20 S Protein of unknown function (DUF1433)
NKPELAJD_01033 4.8e-13 S Protein of unknown function (DUF1433)
NKPELAJD_01034 3.5e-24 S Protein of unknown function (DUF1433)
NKPELAJD_01035 5.4e-13 S Protein of unknown function (DUF1433)
NKPELAJD_01036 5.5e-94 padC Q Phenolic acid decarboxylase
NKPELAJD_01037 1.9e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKPELAJD_01038 8.3e-111 yyaS S Membrane
NKPELAJD_01039 6.8e-98 ywjB H RibD C-terminal domain
NKPELAJD_01041 1.4e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NKPELAJD_01042 5.1e-78 slr K transcriptional
NKPELAJD_01043 1.9e-119 ywqC M biosynthesis protein
NKPELAJD_01044 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NKPELAJD_01045 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NKPELAJD_01046 7.4e-219 epsD GT4 M Glycosyl transferase 4-like
NKPELAJD_01047 5.2e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKPELAJD_01048 5e-215 epsF GT4 M Glycosyl transferases group 1
NKPELAJD_01049 1e-204 epsG S EpsG family
NKPELAJD_01050 1.1e-192 epsH GT2 S Glycosyltransferase like family 2
NKPELAJD_01051 1.9e-203 epsI GM pyruvyl transferase
NKPELAJD_01052 3.4e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NKPELAJD_01053 1.4e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKPELAJD_01054 3.4e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NKPELAJD_01055 1.2e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NKPELAJD_01056 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NKPELAJD_01057 1.4e-189 yvfF GM Exopolysaccharide biosynthesis protein
NKPELAJD_01058 2.7e-32 yvfG S YvfG protein
NKPELAJD_01059 2.6e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NKPELAJD_01060 4.2e-303 yvfH C L-lactate permease
NKPELAJD_01061 7.8e-121 yvfI K COG2186 Transcriptional regulators
NKPELAJD_01062 6.8e-223 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKPELAJD_01063 3.5e-134 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NKPELAJD_01064 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NKPELAJD_01065 1.8e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NKPELAJD_01066 2.3e-31
NKPELAJD_01067 3.7e-148 yobL S Bacterial EndoU nuclease
NKPELAJD_01070 8.2e-17 S leucine-zipper of insertion element IS481
NKPELAJD_01071 3.6e-225 gntP EG COG2610 H gluconate symporter and related permeases
NKPELAJD_01072 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
NKPELAJD_01073 8.5e-151 ybbH_1 K RpiR family transcriptional regulator
NKPELAJD_01074 3.9e-167 3.1.3.104 S hydrolases of the HAD superfamily
NKPELAJD_01075 6.9e-116 yyaS S Membrane
NKPELAJD_01076 1.4e-181 purR7 5.1.1.1 K Transcriptional regulator
NKPELAJD_01077 2.9e-259
NKPELAJD_01078 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NKPELAJD_01079 7.7e-158 yvbV EG EamA-like transporter family
NKPELAJD_01080 1.4e-156 yvbU K Transcriptional regulator
NKPELAJD_01082 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKPELAJD_01083 2.2e-204 araR K transcriptional
NKPELAJD_01084 7.4e-253 araE EGP Major facilitator Superfamily
NKPELAJD_01086 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NKPELAJD_01087 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NKPELAJD_01088 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NKPELAJD_01089 1.5e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NKPELAJD_01090 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NKPELAJD_01091 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NKPELAJD_01092 2.1e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NKPELAJD_01093 1.2e-255 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKPELAJD_01094 4.8e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NKPELAJD_01095 2.8e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
NKPELAJD_01096 1.8e-234 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NKPELAJD_01097 2.6e-150 M Protein involved in cellulose biosynthesis
NKPELAJD_01098 2.5e-143 C WbqC-like protein family
NKPELAJD_01099 4.4e-126 S GlcNAc-PI de-N-acetylase
NKPELAJD_01100 9.4e-180
NKPELAJD_01101 8.6e-213 EGP Major facilitator Superfamily
NKPELAJD_01102 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
NKPELAJD_01103 0.0 tcaA S response to antibiotic
NKPELAJD_01104 4.5e-121 exoY M Membrane
NKPELAJD_01105 5.2e-105 yvbG U UPF0056 membrane protein
NKPELAJD_01106 1.9e-98 yvbF K Belongs to the GbsR family
NKPELAJD_01107 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NKPELAJD_01108 5.9e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NKPELAJD_01109 3.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NKPELAJD_01110 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NKPELAJD_01111 4.3e-76 yvbF K Belongs to the GbsR family
NKPELAJD_01112 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NKPELAJD_01113 1.6e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NKPELAJD_01114 8.5e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NKPELAJD_01115 1.2e-126 mutF V ABC transporter, ATP-binding protein
NKPELAJD_01116 1.1e-122 spaE S ABC-2 family transporter protein
NKPELAJD_01117 3.3e-138 mutG S ABC-2 family transporter protein
NKPELAJD_01118 2.6e-123 K Transcriptional regulatory protein, C terminal
NKPELAJD_01119 1.2e-258 T His Kinase A (phosphoacceptor) domain
NKPELAJD_01120 8.8e-53 yodB K transcriptional
NKPELAJD_01121 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
NKPELAJD_01122 1e-69 K transcriptional
NKPELAJD_01123 6e-35 yvzC K Transcriptional
NKPELAJD_01124 4.8e-24 secG U Preprotein translocase subunit SecG
NKPELAJD_01125 3.7e-142 est 3.1.1.1 S Carboxylesterase
NKPELAJD_01126 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NKPELAJD_01127 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NKPELAJD_01129 4e-50 yrdF K ribonuclease inhibitor
NKPELAJD_01130 7.7e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKPELAJD_01131 4.7e-160 ytlI K LysR substrate binding domain
NKPELAJD_01132 6.6e-101 ytmI K Acetyltransferase (GNAT) domain
NKPELAJD_01133 3.5e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
NKPELAJD_01134 1.9e-147 tcyK M Bacterial periplasmic substrate-binding proteins
NKPELAJD_01135 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
NKPELAJD_01136 2.9e-120 tcyM U Binding-protein-dependent transport system inner membrane component
NKPELAJD_01137 9.5e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NKPELAJD_01138 6.4e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKPELAJD_01139 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
NKPELAJD_01140 5.7e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKPELAJD_01142 2.1e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKPELAJD_01143 4e-195 yvaA 1.1.1.371 S Oxidoreductase
NKPELAJD_01144 6.3e-48 csoR S transcriptional
NKPELAJD_01145 2.6e-29 copZ P Heavy-metal-associated domain
NKPELAJD_01146 0.0 copA 3.6.3.54 P P-type ATPase
NKPELAJD_01147 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NKPELAJD_01148 1.2e-102 bdbD O Thioredoxin
NKPELAJD_01149 2e-73 bdbC O Required for disulfide bond formation in some proteins
NKPELAJD_01150 1.5e-141 S Metallo-peptidase family M12
NKPELAJD_01151 3.1e-99 yvgT S membrane
NKPELAJD_01152 0.0 helD 3.6.4.12 L DNA helicase
NKPELAJD_01153 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NKPELAJD_01154 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NKPELAJD_01155 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NKPELAJD_01156 4.6e-85 yvgO
NKPELAJD_01157 5e-156 yvgN S reductase
NKPELAJD_01158 3e-199 yfiN V COG0842 ABC-type multidrug transport system, permease component
NKPELAJD_01159 6.1e-194 yfiM V ABC-2 type transporter
NKPELAJD_01160 5.6e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
NKPELAJD_01161 6.6e-180 T Histidine kinase
NKPELAJD_01162 2e-112 yfiK K Regulator
NKPELAJD_01163 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
NKPELAJD_01164 1.2e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NKPELAJD_01165 5.9e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NKPELAJD_01166 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NKPELAJD_01167 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NKPELAJD_01168 3.6e-14 S Small spore protein J (Spore_SspJ)
NKPELAJD_01169 1.8e-235 yvsH E Arginine ornithine antiporter
NKPELAJD_01170 4e-178 fhuD P ABC transporter
NKPELAJD_01171 2.1e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_01172 1.2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_01173 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
NKPELAJD_01174 1.1e-66 yvrL S Regulatory protein YrvL
NKPELAJD_01175 1.2e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
NKPELAJD_01176 1.6e-15 S YvrJ protein family
NKPELAJD_01177 2.2e-102 yvrI K RNA polymerase
NKPELAJD_01178 7.3e-36
NKPELAJD_01179 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_01180 0.0 T PhoQ Sensor
NKPELAJD_01181 3.8e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
NKPELAJD_01182 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKPELAJD_01183 9.3e-167 yvrC P ABC transporter substrate-binding protein
NKPELAJD_01184 3.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_01185 1.1e-223 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NKPELAJD_01186 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
NKPELAJD_01187 7.5e-228 yvqJ EGP Major facilitator Superfamily
NKPELAJD_01188 3.3e-46 liaI S membrane
NKPELAJD_01189 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NKPELAJD_01190 2.3e-127 liaG S Putative adhesin
NKPELAJD_01191 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NKPELAJD_01192 2.3e-193 vraS 2.7.13.3 T Histidine kinase
NKPELAJD_01193 3.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKPELAJD_01194 9.6e-203 gerAC S Spore germination B3/ GerAC like, C-terminal
NKPELAJD_01195 2e-184 gerAB E Spore germination protein
NKPELAJD_01196 4.9e-260 gerAA EG Spore germination protein
NKPELAJD_01197 6.6e-24 S Protein of unknown function (DUF3970)
NKPELAJD_01198 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NKPELAJD_01199 2.7e-158 yuxN K Transcriptional regulator
NKPELAJD_01200 3.4e-24
NKPELAJD_01201 3.9e-251 cssS 2.7.13.3 T PhoQ Sensor
NKPELAJD_01202 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_01203 8.3e-241 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKPELAJD_01204 1.6e-79 dps P Belongs to the Dps family
NKPELAJD_01205 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKPELAJD_01206 0.0 pepF2 E COG1164 Oligoendopeptidase F
NKPELAJD_01207 1.9e-45 S YusW-like protein
NKPELAJD_01208 1.4e-150 yusV 3.6.3.34 HP ABC transporter
NKPELAJD_01209 3.3e-39 yusU S Protein of unknown function (DUF2573)
NKPELAJD_01210 1.4e-187 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NKPELAJD_01211 5.9e-140 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
NKPELAJD_01212 4.8e-157 ywbI2 K Transcriptional regulator
NKPELAJD_01213 8.1e-288 yusP P Major facilitator superfamily
NKPELAJD_01214 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
NKPELAJD_01215 1.1e-53 yusN M Coat F domain
NKPELAJD_01216 3.9e-43
NKPELAJD_01217 1.8e-210 yusP P Major facilitator superfamily
NKPELAJD_01218 1.7e-165 fadM E Proline dehydrogenase
NKPELAJD_01219 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NKPELAJD_01220 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NKPELAJD_01221 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NKPELAJD_01222 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NKPELAJD_01223 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NKPELAJD_01224 3.7e-40 yusG S Protein of unknown function (DUF2553)
NKPELAJD_01225 3.7e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NKPELAJD_01226 1.6e-54 yusE CO Thioredoxin
NKPELAJD_01227 5e-57 yusD S SCP-2 sterol transfer family
NKPELAJD_01228 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NKPELAJD_01229 4.4e-94 metI P COG2011 ABC-type metal ion transport system, permease component
NKPELAJD_01230 1.5e-144 metQ P Belongs to the NlpA lipoprotein family
NKPELAJD_01231 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NKPELAJD_01232 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NKPELAJD_01233 1.2e-244 sufD O assembly protein SufD
NKPELAJD_01234 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NKPELAJD_01235 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NKPELAJD_01236 3e-270 sufB O FeS cluster assembly
NKPELAJD_01237 1.7e-81 yncE S Protein of unknown function (DUF2691)
NKPELAJD_01238 1.4e-122 Q ubiE/COQ5 methyltransferase family
NKPELAJD_01239 2.5e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NKPELAJD_01240 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NKPELAJD_01242 2.7e-22 S Sporulation delaying protein SdpA
NKPELAJD_01243 2.6e-76
NKPELAJD_01244 3e-14
NKPELAJD_01245 8.6e-165 K helix_turn_helix, mercury resistance
NKPELAJD_01246 7.9e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NKPELAJD_01247 4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NKPELAJD_01248 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
NKPELAJD_01249 6.9e-164 yurM P COG0395 ABC-type sugar transport system, permease component
NKPELAJD_01250 1e-159 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NKPELAJD_01251 1e-133 yurK K UTRA
NKPELAJD_01252 4.1e-206 msmX P Belongs to the ABC transporter superfamily
NKPELAJD_01253 4.1e-169 bsn L Ribonuclease
NKPELAJD_01254 1.3e-237 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NKPELAJD_01255 1.1e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NKPELAJD_01256 1.2e-211 blt EGP Major facilitator Superfamily
NKPELAJD_01257 9.8e-70
NKPELAJD_01259 2.2e-54 L COG2963 Transposase and inactivated derivatives
NKPELAJD_01260 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
NKPELAJD_01261 1e-88 S Aspartate phosphatase response regulator
NKPELAJD_01264 3.1e-303 pucR QT COG2508 Regulator of polyketide synthase expression
NKPELAJD_01265 9.1e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NKPELAJD_01266 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
NKPELAJD_01267 2.6e-168 yunF S Protein of unknown function DUF72
NKPELAJD_01268 1.8e-145 yunE S membrane transporter protein
NKPELAJD_01269 1.8e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NKPELAJD_01270 8.7e-131 yunB S Sporulation protein YunB (Spo_YunB)
NKPELAJD_01271 6.4e-195 lytH M Peptidase, M23
NKPELAJD_01272 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NKPELAJD_01273 1.7e-47 yutD S protein conserved in bacteria
NKPELAJD_01274 8.6e-75 yutE S Protein of unknown function DUF86
NKPELAJD_01275 7.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NKPELAJD_01276 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NKPELAJD_01277 3.2e-197 yutH S Spore coat protein
NKPELAJD_01278 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
NKPELAJD_01279 4.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NKPELAJD_01280 7.5e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NKPELAJD_01281 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NKPELAJD_01282 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NKPELAJD_01283 3.3e-55 yuzD S protein conserved in bacteria
NKPELAJD_01284 1.9e-208 yutJ 1.6.99.3 C NADH dehydrogenase
NKPELAJD_01285 2.4e-39 yuzB S Belongs to the UPF0349 family
NKPELAJD_01286 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKPELAJD_01287 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NKPELAJD_01288 1.1e-62 erpA S Belongs to the HesB IscA family
NKPELAJD_01289 2.5e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NKPELAJD_01290 6.7e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
NKPELAJD_01292 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
NKPELAJD_01294 7.3e-124 V ABC transporter
NKPELAJD_01295 3.1e-71 CP Membrane
NKPELAJD_01296 4.8e-29
NKPELAJD_01297 2.1e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NKPELAJD_01299 1.1e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
NKPELAJD_01300 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
NKPELAJD_01301 9.9e-28 yuiB S Putative membrane protein
NKPELAJD_01302 4.2e-118 yuiC S protein conserved in bacteria
NKPELAJD_01303 1.2e-77 yuiD S protein conserved in bacteria
NKPELAJD_01304 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NKPELAJD_01305 1.2e-207 yuiF S antiporter
NKPELAJD_01306 1.1e-101 bioY S Biotin biosynthesis protein
NKPELAJD_01307 1.2e-119 yuiH S Oxidoreductase molybdopterin binding domain
NKPELAJD_01308 3.6e-165 besA S Putative esterase
NKPELAJD_01309 1.9e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKPELAJD_01310 5.6e-225 entC 5.4.4.2 HQ Isochorismate synthase
NKPELAJD_01311 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NKPELAJD_01312 7e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NKPELAJD_01313 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_01314 1.3e-34 mbtH S MbtH-like protein
NKPELAJD_01315 2.8e-133 yukJ S Uncharacterized conserved protein (DUF2278)
NKPELAJD_01316 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NKPELAJD_01317 1.5e-228 yukF QT Transcriptional regulator
NKPELAJD_01318 3.3e-46 esxA S Belongs to the WXG100 family
NKPELAJD_01319 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
NKPELAJD_01320 2.8e-206 essB S WXG100 protein secretion system (Wss), protein YukC
NKPELAJD_01321 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NKPELAJD_01322 1.9e-230 esaA S type VII secretion protein EsaA
NKPELAJD_01323 6.9e-78 yueC S Family of unknown function (DUF5383)
NKPELAJD_01324 7.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_01325 3.7e-96 yueE S phosphohydrolase
NKPELAJD_01326 1.6e-22 S Protein of unknown function (DUF2642)
NKPELAJD_01327 1.9e-187 yueF S transporter activity
NKPELAJD_01328 6.4e-34 yueG S Spore germination protein gerPA/gerPF
NKPELAJD_01329 2.8e-38 yueH S YueH-like protein
NKPELAJD_01330 7.2e-68 yueI S Protein of unknown function (DUF1694)
NKPELAJD_01331 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
NKPELAJD_01332 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NKPELAJD_01333 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NKPELAJD_01334 8.9e-51 yuzC
NKPELAJD_01336 1.5e-97 comQ H Belongs to the FPP GGPP synthase family
NKPELAJD_01338 4.7e-273 comP 2.7.13.3 T Histidine kinase
NKPELAJD_01339 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKPELAJD_01340 6.7e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NKPELAJD_01341 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NKPELAJD_01342 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKPELAJD_01343 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKPELAJD_01344 3.2e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKPELAJD_01345 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKPELAJD_01346 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKPELAJD_01347 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NKPELAJD_01348 1.8e-12
NKPELAJD_01349 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
NKPELAJD_01350 1.1e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NKPELAJD_01351 6.1e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NKPELAJD_01352 4.1e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NKPELAJD_01353 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
NKPELAJD_01354 2.2e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NKPELAJD_01355 9.3e-74 yufK S Family of unknown function (DUF5366)
NKPELAJD_01356 2.2e-72 yuxK S protein conserved in bacteria
NKPELAJD_01357 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NKPELAJD_01358 1.7e-179 yuxJ EGP Major facilitator Superfamily
NKPELAJD_01359 4.5e-118 kapD L the KinA pathway to sporulation
NKPELAJD_01360 5.9e-67 kapB G Kinase associated protein B
NKPELAJD_01361 3.6e-230 T PhoQ Sensor
NKPELAJD_01362 9.3e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NKPELAJD_01363 1.4e-40 yugE S Domain of unknown function (DUF1871)
NKPELAJD_01364 1.1e-155 yugF I Hydrolase
NKPELAJD_01365 2e-83 alaR K Transcriptional regulator
NKPELAJD_01366 7.2e-209 yugH 2.6.1.1 E Aminotransferase
NKPELAJD_01367 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NKPELAJD_01368 1.8e-34 yuzA S Domain of unknown function (DUF378)
NKPELAJD_01369 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NKPELAJD_01370 2.1e-229 yugK C Dehydrogenase
NKPELAJD_01371 7.1e-118 ycaC Q Isochorismatase family
NKPELAJD_01372 6.1e-97 S NADPH-dependent FMN reductase
NKPELAJD_01374 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
NKPELAJD_01376 2.8e-72 yugN S YugN-like family
NKPELAJD_01377 7e-181 yugO P COG1226 Kef-type K transport systems
NKPELAJD_01378 1.1e-26 mstX S Membrane-integrating protein Mistic
NKPELAJD_01379 4.5e-18
NKPELAJD_01380 8.3e-117 yugP S Zn-dependent protease
NKPELAJD_01381 8.7e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NKPELAJD_01382 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NKPELAJD_01383 9.7e-76 yugU S Uncharacterised protein family UPF0047
NKPELAJD_01384 5e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NKPELAJD_01385 4.8e-41
NKPELAJD_01386 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NKPELAJD_01387 9.9e-219 mcpA NT chemotaxis protein
NKPELAJD_01388 6.6e-239 mcpA NT chemotaxis protein
NKPELAJD_01389 3.2e-225 mcpA NT chemotaxis protein
NKPELAJD_01390 5.3e-236 mcpA NT chemotaxis protein
NKPELAJD_01391 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NKPELAJD_01392 2.1e-185 ygjR S Oxidoreductase
NKPELAJD_01393 9e-196 yubA S transporter activity
NKPELAJD_01394 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NKPELAJD_01396 1.8e-53 yjcN
NKPELAJD_01397 1.9e-123 G Cupin
NKPELAJD_01398 4.5e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NKPELAJD_01399 5.6e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NKPELAJD_01400 7.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
NKPELAJD_01401 2.1e-94 yuaB
NKPELAJD_01402 2.7e-97 yuaC K Belongs to the GbsR family
NKPELAJD_01403 7.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NKPELAJD_01404 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
NKPELAJD_01405 2.5e-109 yuaD S MOSC domain
NKPELAJD_01406 1.8e-81 yuaE S DinB superfamily
NKPELAJD_01407 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NKPELAJD_01408 4e-175 yuaG 3.4.21.72 S protein conserved in bacteria
NKPELAJD_01409 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
NKPELAJD_01412 7.3e-64 yokH G SMI1 / KNR4 family
NKPELAJD_01413 3.7e-257 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NKPELAJD_01414 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NKPELAJD_01415 4.7e-281 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NKPELAJD_01416 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
NKPELAJD_01417 5e-108 yttP K Transcriptional regulator
NKPELAJD_01418 4.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NKPELAJD_01419 1.2e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NKPELAJD_01420 6.9e-240 braB E Component of the transport system for branched-chain amino acids
NKPELAJD_01421 3.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
NKPELAJD_01422 7.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKPELAJD_01423 3.9e-31 sspB S spore protein
NKPELAJD_01424 8.5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NKPELAJD_01425 0.0 ytcJ S amidohydrolase
NKPELAJD_01426 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKPELAJD_01427 7.1e-181 sppA OU signal peptide peptidase SppA
NKPELAJD_01428 4.5e-88 yteJ S RDD family
NKPELAJD_01429 3.8e-109 ytfI S Protein of unknown function (DUF2953)
NKPELAJD_01430 1.5e-63 ytfJ S Sporulation protein YtfJ
NKPELAJD_01431 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NKPELAJD_01432 2.8e-182 ytxK 2.1.1.72 L DNA methylase
NKPELAJD_01433 7.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NKPELAJD_01434 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NKPELAJD_01435 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NKPELAJD_01436 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
NKPELAJD_01438 4.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_01439 2.5e-129 ytkL S Belongs to the UPF0173 family
NKPELAJD_01440 4.1e-237 ytoI K transcriptional regulator containing CBS domains
NKPELAJD_01441 1.5e-46 ytpI S YtpI-like protein
NKPELAJD_01442 4.6e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NKPELAJD_01443 4.4e-23
NKPELAJD_01444 5.1e-87 ytrI
NKPELAJD_01445 3.2e-56 ytrH S Sporulation protein YtrH
NKPELAJD_01446 0.0 dnaE 2.7.7.7 L DNA polymerase
NKPELAJD_01447 1.7e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
NKPELAJD_01448 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NKPELAJD_01449 1.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NKPELAJD_01450 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NKPELAJD_01451 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NKPELAJD_01452 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NKPELAJD_01453 3.6e-194 ytvI S sporulation integral membrane protein YtvI
NKPELAJD_01454 1.5e-72 yeaL S membrane
NKPELAJD_01455 8.6e-48
NKPELAJD_01456 6.2e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NKPELAJD_01457 3.1e-242 icd 1.1.1.42 C isocitrate
NKPELAJD_01458 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NKPELAJD_01459 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_01460 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NKPELAJD_01461 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NKPELAJD_01462 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NKPELAJD_01463 2.1e-106 ytaF P Probably functions as a manganese efflux pump
NKPELAJD_01464 2.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NKPELAJD_01465 1.5e-160 ytbE S reductase
NKPELAJD_01466 1.4e-204 ytbD EGP Major facilitator Superfamily
NKPELAJD_01467 2e-67 ytcD K Transcriptional regulator
NKPELAJD_01468 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NKPELAJD_01469 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NKPELAJD_01470 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NKPELAJD_01471 4.2e-256 dnaB L Membrane attachment protein
NKPELAJD_01472 4.3e-172 dnaI L Primosomal protein DnaI
NKPELAJD_01473 2.7e-109 ytxB S SNARE associated Golgi protein
NKPELAJD_01474 6.7e-153 ytxC S YtxC-like family
NKPELAJD_01475 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKPELAJD_01476 7.9e-151 ysaA S HAD-hyrolase-like
NKPELAJD_01477 0.0 lytS 2.7.13.3 T Histidine kinase
NKPELAJD_01478 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
NKPELAJD_01479 3.1e-40 lrgA S effector of murein hydrolase LrgA
NKPELAJD_01480 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NKPELAJD_01481 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NKPELAJD_01482 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NKPELAJD_01483 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NKPELAJD_01484 7e-43 ysdA S Membrane
NKPELAJD_01485 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NKPELAJD_01486 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
NKPELAJD_01487 5.2e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NKPELAJD_01488 8.1e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NKPELAJD_01489 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NKPELAJD_01490 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NKPELAJD_01491 4.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NKPELAJD_01492 1.5e-225 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NKPELAJD_01493 5.2e-253 araN G carbohydrate transport
NKPELAJD_01494 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
NKPELAJD_01495 1.2e-144 araQ G transport system permease
NKPELAJD_01496 3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NKPELAJD_01497 0.0 cstA T Carbon starvation protein
NKPELAJD_01498 9.8e-255 glcF C Glycolate oxidase
NKPELAJD_01499 9.1e-259 glcD 1.1.3.15 C FAD binding domain
NKPELAJD_01500 4.9e-204 ysfB KT regulator
NKPELAJD_01501 2e-32 sspI S Belongs to the SspI family
NKPELAJD_01502 7e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKPELAJD_01503 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NKPELAJD_01504 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NKPELAJD_01505 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKPELAJD_01506 7.7e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NKPELAJD_01507 3.6e-83 cvpA S membrane protein, required for colicin V production
NKPELAJD_01508 0.0 polX L COG1796 DNA polymerase IV (family X)
NKPELAJD_01509 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NKPELAJD_01510 4.7e-67 yshE S membrane
NKPELAJD_01511 8.2e-125 ywbB S Protein of unknown function (DUF2711)
NKPELAJD_01512 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NKPELAJD_01513 9.2e-104 fadR K Transcriptional regulator
NKPELAJD_01514 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NKPELAJD_01515 2e-138 etfB C Electron transfer flavoprotein
NKPELAJD_01516 9.3e-178 etfA C Electron transfer flavoprotein
NKPELAJD_01517 1.1e-244 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NKPELAJD_01518 2.5e-52 trxA O Belongs to the thioredoxin family
NKPELAJD_01519 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NKPELAJD_01520 4.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NKPELAJD_01521 7.7e-79 yslB S Protein of unknown function (DUF2507)
NKPELAJD_01522 4.8e-108 sdhC C succinate dehydrogenase
NKPELAJD_01523 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NKPELAJD_01524 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NKPELAJD_01525 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NKPELAJD_01526 2e-30 gerE K Transcriptional regulator
NKPELAJD_01527 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_01528 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NKPELAJD_01529 2.4e-198 gerM S COG5401 Spore germination protein
NKPELAJD_01530 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NKPELAJD_01531 2.5e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NKPELAJD_01532 1.5e-91 ysnB S Phosphoesterase
NKPELAJD_01537 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NKPELAJD_01538 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
NKPELAJD_01539 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NKPELAJD_01540 3.5e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NKPELAJD_01541 8.2e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NKPELAJD_01542 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKPELAJD_01543 1.8e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKPELAJD_01544 5.4e-189 ysoA H Tetratricopeptide repeat
NKPELAJD_01545 1.7e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NKPELAJD_01546 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NKPELAJD_01547 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NKPELAJD_01548 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NKPELAJD_01549 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
NKPELAJD_01550 3.8e-87 ysxD
NKPELAJD_01551 2.4e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NKPELAJD_01552 3.6e-146 hemX O cytochrome C
NKPELAJD_01553 9.2e-74 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NKPELAJD_01554 1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NKPELAJD_01555 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
NKPELAJD_01556 3.6e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NKPELAJD_01557 7.7e-124 spoVID M stage VI sporulation protein D
NKPELAJD_01558 1.2e-196 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NKPELAJD_01559 2.1e-25
NKPELAJD_01560 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NKPELAJD_01561 3.9e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NKPELAJD_01562 2.3e-131 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NKPELAJD_01563 6.3e-137 spoIIB S Sporulation related domain
NKPELAJD_01564 1.2e-100 maf D septum formation protein Maf
NKPELAJD_01565 1.8e-127 radC E Belongs to the UPF0758 family
NKPELAJD_01566 4e-184 mreB D Rod shape-determining protein MreB
NKPELAJD_01567 1.2e-157 mreC M Involved in formation and maintenance of cell shape
NKPELAJD_01568 1.4e-84 mreD M shape-determining protein
NKPELAJD_01569 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NKPELAJD_01570 2.3e-142 minD D Belongs to the ParA family
NKPELAJD_01571 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NKPELAJD_01572 1.2e-160 spoIVFB S Stage IV sporulation protein
NKPELAJD_01573 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
NKPELAJD_01574 3.2e-56 ysxB J ribosomal protein
NKPELAJD_01575 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NKPELAJD_01576 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NKPELAJD_01577 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NKPELAJD_01578 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NKPELAJD_01579 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
NKPELAJD_01580 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
NKPELAJD_01581 1.7e-223 nifS 2.8.1.7 E Cysteine desulfurase
NKPELAJD_01582 4.5e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NKPELAJD_01583 7.4e-155 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NKPELAJD_01584 8.2e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NKPELAJD_01585 1e-146 safA M spore coat assembly protein SafA
NKPELAJD_01586 2.7e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKPELAJD_01588 4.8e-93 bofC S BofC C-terminal domain
NKPELAJD_01589 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NKPELAJD_01590 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NKPELAJD_01591 1.6e-20 yrzS S Protein of unknown function (DUF2905)
NKPELAJD_01592 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NKPELAJD_01593 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NKPELAJD_01594 2.5e-37 yajC U Preprotein translocase subunit YajC
NKPELAJD_01595 3.1e-60 yrzE S Protein of unknown function (DUF3792)
NKPELAJD_01596 3.6e-109 yrbG S membrane
NKPELAJD_01597 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKPELAJD_01598 1.3e-50 yrzD S Post-transcriptional regulator
NKPELAJD_01599 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NKPELAJD_01600 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NKPELAJD_01601 1.7e-46 yrvD S Lipopolysaccharide assembly protein A domain
NKPELAJD_01602 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NKPELAJD_01603 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NKPELAJD_01604 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NKPELAJD_01605 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NKPELAJD_01606 3.8e-274 lytH 3.5.1.28 M COG3103 SH3 domain protein
NKPELAJD_01609 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NKPELAJD_01610 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NKPELAJD_01611 9.6e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NKPELAJD_01612 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NKPELAJD_01613 7.8e-64 cymR K Transcriptional regulator
NKPELAJD_01614 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
NKPELAJD_01615 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NKPELAJD_01616 1.7e-18 S COG0457 FOG TPR repeat
NKPELAJD_01617 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NKPELAJD_01618 1.8e-83 yrrD S protein conserved in bacteria
NKPELAJD_01619 2.9e-30 yrzR
NKPELAJD_01620 2.1e-08 S Protein of unknown function (DUF3918)
NKPELAJD_01621 4.4e-107 glnP P ABC transporter
NKPELAJD_01622 1.2e-109 gluC P ABC transporter
NKPELAJD_01623 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
NKPELAJD_01624 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NKPELAJD_01625 5.2e-166 yrrI S AI-2E family transporter
NKPELAJD_01626 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NKPELAJD_01627 8.5e-41 yrzL S Belongs to the UPF0297 family
NKPELAJD_01628 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NKPELAJD_01629 7.1e-46 yrzB S Belongs to the UPF0473 family
NKPELAJD_01630 9.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NKPELAJD_01631 2.1e-117 yrrM 2.1.1.104 S O-methyltransferase
NKPELAJD_01632 1.7e-173 yegQ O Peptidase U32
NKPELAJD_01633 1.6e-246 yegQ O COG0826 Collagenase and related proteases
NKPELAJD_01634 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
NKPELAJD_01635 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NKPELAJD_01636 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NKPELAJD_01637 3.4e-68 yrrS S Protein of unknown function (DUF1510)
NKPELAJD_01638 4.1e-27 yrzA S Protein of unknown function (DUF2536)
NKPELAJD_01639 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NKPELAJD_01640 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NKPELAJD_01641 4.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NKPELAJD_01642 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NKPELAJD_01643 1.8e-34 yrhC S YrhC-like protein
NKPELAJD_01644 1e-79 yrhD S Protein of unknown function (DUF1641)
NKPELAJD_01645 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
NKPELAJD_01646 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
NKPELAJD_01647 8e-143 focA P Formate nitrite
NKPELAJD_01649 3.9e-93 yrhH Q methyltransferase
NKPELAJD_01650 9.1e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NKPELAJD_01651 9.9e-266 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NKPELAJD_01652 2.5e-212 ynfM EGP Major facilitator Superfamily
NKPELAJD_01653 1.1e-164 yybE K Transcriptional regulator
NKPELAJD_01654 1.1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NKPELAJD_01655 3.1e-183 romA S Beta-lactamase superfamily domain
NKPELAJD_01656 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NKPELAJD_01657 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NKPELAJD_01658 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NKPELAJD_01659 1.5e-127 glvR K Helix-turn-helix domain, rpiR family
NKPELAJD_01660 1.2e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
NKPELAJD_01661 9.1e-147 S hydrolase
NKPELAJD_01663 1.1e-92 yrdA S DinB family
NKPELAJD_01664 1.3e-80 yyaR K Acetyltransferase (GNAT) domain
NKPELAJD_01665 5.3e-219 tetL EGP Major facilitator Superfamily
NKPELAJD_01666 1.5e-97 adk 2.7.4.3 F adenylate kinase activity
NKPELAJD_01667 3.9e-21 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
NKPELAJD_01668 3.1e-148 ydeE K AraC family transcriptional regulator
NKPELAJD_01669 4.4e-89 K Transcriptional regulator PadR-like family
NKPELAJD_01670 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
NKPELAJD_01671 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKPELAJD_01672 3.2e-215 EGP Major facilitator Superfamily
NKPELAJD_01673 7.4e-31 2.3.1.57 K Acetyltransferase (GNAT) domain
NKPELAJD_01674 4e-141 3.5.1.104 G Polysaccharide deacetylase
NKPELAJD_01675 7.7e-140 yqeF E GDSL-like Lipase/Acylhydrolase
NKPELAJD_01677 2.6e-94 yqeG S hydrolase of the HAD superfamily
NKPELAJD_01678 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NKPELAJD_01679 6e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NKPELAJD_01680 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NKPELAJD_01681 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NKPELAJD_01682 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NKPELAJD_01683 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NKPELAJD_01684 2.2e-139 yqeM Q Methyltransferase
NKPELAJD_01685 5e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKPELAJD_01686 3.6e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NKPELAJD_01687 8e-105 comEB 3.5.4.12 F ComE operon protein 2
NKPELAJD_01688 0.0 comEC S Competence protein ComEC
NKPELAJD_01689 1.1e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
NKPELAJD_01690 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
NKPELAJD_01691 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NKPELAJD_01692 1.4e-220 spoIIP M stage II sporulation protein P
NKPELAJD_01693 3.8e-54 yqxA S Protein of unknown function (DUF3679)
NKPELAJD_01694 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NKPELAJD_01695 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NKPELAJD_01696 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NKPELAJD_01697 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NKPELAJD_01698 0.0 dnaK O Heat shock 70 kDa protein
NKPELAJD_01699 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NKPELAJD_01700 1.6e-174 prmA J Methylates ribosomal protein L11
NKPELAJD_01701 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NKPELAJD_01702 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NKPELAJD_01703 1.3e-157 yqeW P COG1283 Na phosphate symporter
NKPELAJD_01704 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NKPELAJD_01705 1.2e-68 yqeY S Yqey-like protein
NKPELAJD_01706 2e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NKPELAJD_01707 1.6e-121 yqfA S UPF0365 protein
NKPELAJD_01708 3.4e-55 yqfB
NKPELAJD_01709 9.3e-46 yqfC S sporulation protein YqfC
NKPELAJD_01710 4.2e-217 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NKPELAJD_01711 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
NKPELAJD_01712 0.0 yqfF S membrane-associated HD superfamily hydrolase
NKPELAJD_01713 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NKPELAJD_01714 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NKPELAJD_01715 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NKPELAJD_01716 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NKPELAJD_01717 1.8e-16 S YqzL-like protein
NKPELAJD_01718 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
NKPELAJD_01719 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NKPELAJD_01720 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NKPELAJD_01721 4.5e-112 ccpN K CBS domain
NKPELAJD_01722 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NKPELAJD_01723 6.1e-88 yaiI S Belongs to the UPF0178 family
NKPELAJD_01724 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NKPELAJD_01725 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NKPELAJD_01726 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
NKPELAJD_01727 2.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
NKPELAJD_01728 3.6e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NKPELAJD_01729 4.9e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NKPELAJD_01730 6.2e-51 yqfQ S YqfQ-like protein
NKPELAJD_01731 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NKPELAJD_01732 6.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NKPELAJD_01733 9.3e-37 yqfT S Protein of unknown function (DUF2624)
NKPELAJD_01734 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NKPELAJD_01735 2.9e-72 zur P Belongs to the Fur family
NKPELAJD_01736 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NKPELAJD_01737 2.3e-52 yqfX S membrane
NKPELAJD_01738 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NKPELAJD_01739 3.7e-48 yqfZ M LysM domain
NKPELAJD_01740 8.7e-131 yqgB S Protein of unknown function (DUF1189)
NKPELAJD_01741 6e-77 yqgC S protein conserved in bacteria
NKPELAJD_01742 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NKPELAJD_01743 4.5e-228 yqgE EGP Major facilitator superfamily
NKPELAJD_01744 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NKPELAJD_01745 1.9e-156 pstS P Phosphate
NKPELAJD_01746 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NKPELAJD_01747 1.8e-156 pstA P Phosphate transport system permease
NKPELAJD_01748 3.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NKPELAJD_01749 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NKPELAJD_01750 1.4e-72 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NKPELAJD_01751 1.2e-50 yqzD
NKPELAJD_01752 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NKPELAJD_01753 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NKPELAJD_01754 4e-07 yqgO
NKPELAJD_01755 4.1e-232 nhaC C Na H antiporter
NKPELAJD_01756 1e-28 yqgQ S Protein conserved in bacteria
NKPELAJD_01757 2.2e-179 glcK 2.7.1.2 G Glucokinase
NKPELAJD_01758 1.9e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NKPELAJD_01759 1.6e-199 yqgU
NKPELAJD_01760 6.9e-50 yqgV S Thiamine-binding protein
NKPELAJD_01761 5.4e-20 yqgW S Protein of unknown function (DUF2759)
NKPELAJD_01762 1.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NKPELAJD_01763 3.1e-37 yqgY S Protein of unknown function (DUF2626)
NKPELAJD_01764 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
NKPELAJD_01766 1.6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKPELAJD_01767 6.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NKPELAJD_01768 9e-186 corA P Mg2 transporter protein
NKPELAJD_01769 7.8e-202 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NKPELAJD_01770 4.1e-184 comGB NU COG1459 Type II secretory pathway, component PulF
NKPELAJD_01771 8.9e-50 comGC U Required for transformation and DNA binding
NKPELAJD_01772 6.2e-73 gspH NU Tfp pilus assembly protein FimT
NKPELAJD_01773 7.6e-20 comGE
NKPELAJD_01774 3e-66 comGF U Putative Competence protein ComGF
NKPELAJD_01775 1.2e-61 S ComG operon protein 7
NKPELAJD_01776 2.3e-26 yqzE S YqzE-like protein
NKPELAJD_01777 8.3e-54 yqzG S Protein of unknown function (DUF3889)
NKPELAJD_01778 3.8e-122 yqxM
NKPELAJD_01779 1.3e-70 sipW 3.4.21.89 U Signal peptidase
NKPELAJD_01780 3.3e-141 tasA S Cell division protein FtsN
NKPELAJD_01781 7.8e-55 sinR K transcriptional
NKPELAJD_01782 3.4e-22 sinI S Anti-repressor SinI
NKPELAJD_01783 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
NKPELAJD_01784 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NKPELAJD_01785 2.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NKPELAJD_01786 1.9e-250 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NKPELAJD_01787 1.5e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NKPELAJD_01788 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
NKPELAJD_01789 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NKPELAJD_01790 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NKPELAJD_01791 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
NKPELAJD_01792 3.4e-62 yqhP
NKPELAJD_01793 1e-173 yqhQ S Protein of unknown function (DUF1385)
NKPELAJD_01794 3.7e-88 yqhR S Conserved membrane protein YqhR
NKPELAJD_01795 1.1e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NKPELAJD_01796 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NKPELAJD_01797 1.8e-36 yqhV S Protein of unknown function (DUF2619)
NKPELAJD_01798 4.2e-172 spoIIIAA S stage III sporulation protein AA
NKPELAJD_01799 1.7e-85 spoIIIAB S Stage III sporulation protein
NKPELAJD_01800 7.6e-29 spoIIIAC S stage III sporulation protein AC
NKPELAJD_01801 2.5e-41 spoIIIAD S Stage III sporulation protein AD
NKPELAJD_01802 1.4e-199 spoIIIAE S stage III sporulation protein AE
NKPELAJD_01803 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NKPELAJD_01804 3.4e-118 spoIIIAG S stage III sporulation protein AG
NKPELAJD_01805 2.5e-62 spoIIIAH S SpoIIIAH-like protein
NKPELAJD_01806 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NKPELAJD_01807 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NKPELAJD_01808 8.1e-67 yqhY S protein conserved in bacteria
NKPELAJD_01809 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NKPELAJD_01810 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NKPELAJD_01811 5.1e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NKPELAJD_01812 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NKPELAJD_01813 2.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NKPELAJD_01814 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NKPELAJD_01815 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NKPELAJD_01816 3.9e-78 argR K Regulates arginine biosynthesis genes
NKPELAJD_01817 2.7e-305 recN L May be involved in recombinational repair of damaged DNA
NKPELAJD_01818 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
NKPELAJD_01819 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NKPELAJD_01820 1.4e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKPELAJD_01823 3.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NKPELAJD_01825 1.8e-113 K Protein of unknown function (DUF1232)
NKPELAJD_01826 1.5e-101 ytaF P Probably functions as a manganese efflux pump
NKPELAJD_01827 2.5e-17
NKPELAJD_01828 1.2e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NKPELAJD_01829 3.3e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NKPELAJD_01830 1.7e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
NKPELAJD_01831 4.8e-154 hbdA 1.1.1.157 I Dehydrogenase
NKPELAJD_01832 1.6e-205 mmgC I acyl-CoA dehydrogenase
NKPELAJD_01833 9.9e-21 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NKPELAJD_01834 1.4e-161 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NKPELAJD_01835 2e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NKPELAJD_01836 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NKPELAJD_01837 3.2e-34 yqzF S Protein of unknown function (DUF2627)
NKPELAJD_01838 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NKPELAJD_01839 2.8e-152 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NKPELAJD_01840 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NKPELAJD_01841 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
NKPELAJD_01842 1.8e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKPELAJD_01843 7.5e-167 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKPELAJD_01844 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKPELAJD_01845 1.8e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKPELAJD_01846 1.6e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NKPELAJD_01847 1e-75 yqiW S Belongs to the UPF0403 family
NKPELAJD_01848 9e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NKPELAJD_01849 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
NKPELAJD_01850 2.2e-126 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NKPELAJD_01851 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
NKPELAJD_01852 5.4e-95 yqjB S protein conserved in bacteria
NKPELAJD_01854 1.1e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NKPELAJD_01855 4.8e-290 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NKPELAJD_01856 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NKPELAJD_01857 4.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NKPELAJD_01858 2.4e-25 yqzJ
NKPELAJD_01859 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKPELAJD_01860 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NKPELAJD_01861 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NKPELAJD_01862 3.3e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NKPELAJD_01863 1.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NKPELAJD_01864 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NKPELAJD_01865 2.5e-50 S GlpM protein
NKPELAJD_01866 5.8e-163 K LysR substrate binding domain
NKPELAJD_01867 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
NKPELAJD_01868 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKPELAJD_01871 4.1e-248 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NKPELAJD_01872 5.5e-130 IQ reductase
NKPELAJD_01873 0.0 pksJ Q Polyketide synthase of type I
NKPELAJD_01874 0.0 pksJ Q Polyketide synthase of type I
NKPELAJD_01875 0.0 1.1.1.320 Q Polyketide synthase of type I
NKPELAJD_01876 0.0 Q Polyketide synthase of type I
NKPELAJD_01877 0.0 pksJ Q Polyketide synthase of type I
NKPELAJD_01878 0.0 pfaA Q Polyketide synthase of type I
NKPELAJD_01879 0.0 Q Polyketide synthase of type I
NKPELAJD_01880 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NKPELAJD_01881 1.7e-218 eryK 1.14.13.154 C Cytochrome P450
NKPELAJD_01882 6.4e-240 pksG 2.3.3.10 I synthase
NKPELAJD_01883 7.5e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NKPELAJD_01884 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKPELAJD_01885 7.2e-175 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NKPELAJD_01886 4.2e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NKPELAJD_01887 1.8e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NKPELAJD_01888 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NKPELAJD_01889 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKPELAJD_01891 2.5e-176 yueF S transporter activity
NKPELAJD_01893 7.6e-58 S YolD-like protein
NKPELAJD_01894 9.4e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKPELAJD_01895 6.6e-89 yqjY K acetyltransferase
NKPELAJD_01896 1.6e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NKPELAJD_01897 7.7e-177 yqkA K GrpB protein
NKPELAJD_01898 2.9e-60 yqkB S Belongs to the HesB IscA family
NKPELAJD_01899 3.2e-39 yqkC S Protein of unknown function (DUF2552)
NKPELAJD_01900 6.2e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NKPELAJD_01902 3.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NKPELAJD_01904 8.7e-72 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NKPELAJD_01905 2.4e-220 yqxK 3.6.4.12 L DNA helicase
NKPELAJD_01906 3e-57 ansR K Transcriptional regulator
NKPELAJD_01907 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
NKPELAJD_01908 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NKPELAJD_01909 1.1e-237 mleN C Na H antiporter
NKPELAJD_01910 7.7e-244 mleA 1.1.1.38 C malic enzyme
NKPELAJD_01911 5.7e-22
NKPELAJD_01912 1.7e-34 yqkK
NKPELAJD_01914 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NKPELAJD_01915 1.9e-80 fur P Belongs to the Fur family
NKPELAJD_01916 9.2e-36 S Protein of unknown function (DUF4227)
NKPELAJD_01917 1.8e-164 xerD L recombinase XerD
NKPELAJD_01918 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NKPELAJD_01919 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NKPELAJD_01920 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NKPELAJD_01921 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NKPELAJD_01922 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NKPELAJD_01923 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKPELAJD_01924 3.7e-111 spoVAA S Stage V sporulation protein AA
NKPELAJD_01925 3e-60 spoVAB S Stage V sporulation protein AB
NKPELAJD_01926 2.1e-79 spoVAC S stage V sporulation protein AC
NKPELAJD_01927 3.5e-70 spoVAD I Stage V sporulation protein AD
NKPELAJD_01928 3.8e-57 spoVAEB S stage V sporulation protein
NKPELAJD_01929 1.8e-110 spoVAEA S stage V sporulation protein
NKPELAJD_01930 1.4e-270 spoVAF EG Stage V sporulation protein AF
NKPELAJD_01931 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NKPELAJD_01932 6e-155 ypuA S Secreted protein
NKPELAJD_01933 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NKPELAJD_01934 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
NKPELAJD_01935 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NKPELAJD_01936 1.7e-49 ypuD
NKPELAJD_01937 2.8e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NKPELAJD_01938 2.9e-111 ribE 2.5.1.9 H Riboflavin synthase
NKPELAJD_01939 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NKPELAJD_01940 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NKPELAJD_01941 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKPELAJD_01942 6.4e-93 ypuF S Domain of unknown function (DUF309)
NKPELAJD_01944 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NKPELAJD_01945 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NKPELAJD_01946 1.3e-93 ypuI S Protein of unknown function (DUF3907)
NKPELAJD_01947 6.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NKPELAJD_01948 2e-103 spmA S Spore maturation protein
NKPELAJD_01949 2.9e-88 spmB S Spore maturation protein
NKPELAJD_01950 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NKPELAJD_01951 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NKPELAJD_01952 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NKPELAJD_01953 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NKPELAJD_01954 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_01955 0.0 resE 2.7.13.3 T Histidine kinase
NKPELAJD_01956 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NKPELAJD_01957 1.2e-197 rsiX
NKPELAJD_01958 1.3e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKPELAJD_01959 1.4e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NKPELAJD_01960 3.6e-41 fer C Ferredoxin
NKPELAJD_01961 2.7e-199 ypbB 5.1.3.1 S protein conserved in bacteria
NKPELAJD_01962 4.2e-272 recQ 3.6.4.12 L DNA helicase
NKPELAJD_01963 2.9e-99 ypbD S metal-dependent membrane protease
NKPELAJD_01964 3.3e-77 ypbE M Lysin motif
NKPELAJD_01965 1.7e-84 ypbF S Protein of unknown function (DUF2663)
NKPELAJD_01966 5.3e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NKPELAJD_01967 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NKPELAJD_01968 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NKPELAJD_01969 1.2e-105 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NKPELAJD_01970 8.9e-59 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NKPELAJD_01971 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
NKPELAJD_01972 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NKPELAJD_01973 8.7e-251 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NKPELAJD_01974 1.6e-61 ypfA M Flagellar protein YcgR
NKPELAJD_01975 1.4e-12 S Family of unknown function (DUF5359)
NKPELAJD_01976 3.3e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NKPELAJD_01977 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
NKPELAJD_01978 5.9e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NKPELAJD_01979 4.7e-08 S YpzI-like protein
NKPELAJD_01980 1.4e-104 yphA
NKPELAJD_01981 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NKPELAJD_01982 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NKPELAJD_01983 3.3e-16 yphE S Protein of unknown function (DUF2768)
NKPELAJD_01984 3.6e-134 yphF
NKPELAJD_01985 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NKPELAJD_01986 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NKPELAJD_01987 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
NKPELAJD_01988 6.6e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NKPELAJD_01989 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NKPELAJD_01990 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NKPELAJD_01991 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NKPELAJD_01992 1.2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NKPELAJD_01993 1.2e-139 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NKPELAJD_01994 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NKPELAJD_01995 7.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NKPELAJD_01996 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NKPELAJD_01997 4.7e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NKPELAJD_01998 1.6e-135 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NKPELAJD_01999 7.3e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NKPELAJD_02000 4.7e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NKPELAJD_02001 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NKPELAJD_02002 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NKPELAJD_02003 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NKPELAJD_02004 6.6e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NKPELAJD_02005 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NKPELAJD_02006 1.7e-232 S COG0457 FOG TPR repeat
NKPELAJD_02007 2.1e-99 ypiB S Belongs to the UPF0302 family
NKPELAJD_02008 3.2e-77 ypiF S Protein of unknown function (DUF2487)
NKPELAJD_02009 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NKPELAJD_02010 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NKPELAJD_02011 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NKPELAJD_02012 1.2e-103 ypjA S membrane
NKPELAJD_02013 5.1e-142 ypjB S sporulation protein
NKPELAJD_02014 1.2e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
NKPELAJD_02015 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NKPELAJD_02016 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NKPELAJD_02017 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NKPELAJD_02018 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NKPELAJD_02019 6.2e-131 bshB1 S proteins, LmbE homologs
NKPELAJD_02020 2.2e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NKPELAJD_02021 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NKPELAJD_02022 1.1e-135 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NKPELAJD_02023 3.8e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NKPELAJD_02024 1e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NKPELAJD_02025 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NKPELAJD_02026 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NKPELAJD_02027 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NKPELAJD_02028 4e-81 ypmB S protein conserved in bacteria
NKPELAJD_02029 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NKPELAJD_02030 2.9e-251 asnS 6.1.1.22 J asparaginyl-tRNA
NKPELAJD_02031 3e-130 dnaD L DNA replication protein DnaD
NKPELAJD_02032 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NKPELAJD_02033 8.2e-90 ypoC
NKPELAJD_02034 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NKPELAJD_02035 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NKPELAJD_02036 7.5e-188 yppC S Protein of unknown function (DUF2515)
NKPELAJD_02039 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
NKPELAJD_02041 6.4e-38 yppG S YppG-like protein
NKPELAJD_02042 6.5e-72 hspX O Belongs to the small heat shock protein (HSP20) family
NKPELAJD_02043 7.9e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NKPELAJD_02044 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NKPELAJD_02045 1.1e-236 yprB L RNase_H superfamily
NKPELAJD_02047 9.9e-33 cotD S Inner spore coat protein D
NKPELAJD_02048 4.8e-99 ypsA S Belongs to the UPF0398 family
NKPELAJD_02049 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NKPELAJD_02050 4.2e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NKPELAJD_02051 6.6e-22 S YpzG-like protein
NKPELAJD_02053 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NKPELAJD_02054 5.4e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NKPELAJD_02055 1.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NKPELAJD_02056 1.3e-235 pbuX F xanthine
NKPELAJD_02058 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
NKPELAJD_02059 3.9e-61 ydfR S Protein of unknown function (DUF421)
NKPELAJD_02061 5.8e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NKPELAJD_02062 1.5e-109 J Acetyltransferase (GNAT) domain
NKPELAJD_02063 2.5e-203 bcsA Q Naringenin-chalcone synthase
NKPELAJD_02064 2.5e-89 ypbQ S protein conserved in bacteria
NKPELAJD_02065 0.0 ypbR S Dynamin family
NKPELAJD_02066 3.5e-39 ypbS S Protein of unknown function (DUF2533)
NKPELAJD_02068 4.1e-164 polA 2.7.7.7 L 5'3' exonuclease
NKPELAJD_02070 1.6e-67 rnhA 3.1.26.4 L Ribonuclease
NKPELAJD_02071 8.9e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NKPELAJD_02072 1.5e-123 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NKPELAJD_02073 1.5e-28 ypeQ S Zinc-finger
NKPELAJD_02074 1.2e-36 S Protein of unknown function (DUF2564)
NKPELAJD_02075 1.3e-11 degR
NKPELAJD_02076 1e-30 cspD K Cold-shock protein
NKPELAJD_02077 3.2e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NKPELAJD_02078 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NKPELAJD_02079 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NKPELAJD_02080 5.9e-98 ypgQ S phosphohydrolase
NKPELAJD_02081 2.3e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
NKPELAJD_02082 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NKPELAJD_02083 1e-75 yphP S Belongs to the UPF0403 family
NKPELAJD_02084 1.3e-129 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NKPELAJD_02085 2.7e-114 ypjP S YpjP-like protein
NKPELAJD_02086 1.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKPELAJD_02087 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NKPELAJD_02088 1.8e-113 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NKPELAJD_02089 9.3e-110 hlyIII S protein, Hemolysin III
NKPELAJD_02090 5e-179 pspF K Transcriptional regulator
NKPELAJD_02091 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NKPELAJD_02092 2.6e-39 ypmP S Protein of unknown function (DUF2535)
NKPELAJD_02093 3e-107 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NKPELAJD_02094 8.9e-136 ypmR E GDSL-like Lipase/Acylhydrolase
NKPELAJD_02095 5.5e-98 ypmS S protein conserved in bacteria
NKPELAJD_02096 1.4e-66 ypoP K transcriptional
NKPELAJD_02097 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKPELAJD_02098 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NKPELAJD_02099 1.1e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
NKPELAJD_02100 1e-220 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NKPELAJD_02101 1.2e-180 cgeB S Spore maturation protein
NKPELAJD_02102 1.6e-52 cgeA
NKPELAJD_02103 1.1e-41 cgeC
NKPELAJD_02104 3.2e-247 cgeD M maturation of the outermost layer of the spore
NKPELAJD_02105 3.2e-144 yiiD K acetyltransferase
NKPELAJD_02107 1.8e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKPELAJD_02108 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NKPELAJD_02109 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NKPELAJD_02110 1.5e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
NKPELAJD_02111 4.3e-158 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NKPELAJD_02112 7.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
NKPELAJD_02113 2e-45 yokU S YokU-like protein, putative antitoxin
NKPELAJD_02114 4.1e-36 yozE S Belongs to the UPF0346 family
NKPELAJD_02115 4.9e-125 yodN
NKPELAJD_02117 6.2e-24 yozD S YozD-like protein
NKPELAJD_02118 1.1e-102 yodM 3.6.1.27 I Acid phosphatase homologues
NKPELAJD_02119 3.3e-55 yodL S YodL-like
NKPELAJD_02121 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NKPELAJD_02122 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NKPELAJD_02123 1.1e-34 yodI
NKPELAJD_02124 2.8e-128 yodH Q Methyltransferase
NKPELAJD_02125 1e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NKPELAJD_02126 5.2e-133 yydK K Transcriptional regulator
NKPELAJD_02127 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NKPELAJD_02128 1.2e-282 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
NKPELAJD_02129 4.6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKPELAJD_02130 3.5e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
NKPELAJD_02131 1.3e-110 mhqD S Carboxylesterase
NKPELAJD_02132 4.5e-106 yodC C nitroreductase
NKPELAJD_02133 4e-56 yodB K transcriptional
NKPELAJD_02134 5.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
NKPELAJD_02135 3.5e-67 yodA S tautomerase
NKPELAJD_02137 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
NKPELAJD_02138 2.3e-162 rarD S -transporter
NKPELAJD_02139 4.9e-23
NKPELAJD_02140 3.7e-60 yojF S Protein of unknown function (DUF1806)
NKPELAJD_02141 4.3e-126 yojG S deacetylase
NKPELAJD_02142 2.9e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKPELAJD_02143 4.8e-241 norM V Multidrug efflux pump
NKPELAJD_02145 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NKPELAJD_02146 3e-226 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NKPELAJD_02147 9.5e-228 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NKPELAJD_02148 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NKPELAJD_02149 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
NKPELAJD_02150 0.0 yojO P Von Willebrand factor
NKPELAJD_02151 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NKPELAJD_02152 1.9e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NKPELAJD_02153 4.4e-143 S Metallo-beta-lactamase superfamily
NKPELAJD_02154 2.5e-159 yocS S -transporter
NKPELAJD_02155 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NKPELAJD_02156 2.9e-159 sodA 1.15.1.1 P Superoxide dismutase
NKPELAJD_02157 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NKPELAJD_02158 9.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NKPELAJD_02159 1.6e-31 yozC
NKPELAJD_02161 2.4e-56 yozO S Bacterial PH domain
NKPELAJD_02162 8.5e-37 yocN
NKPELAJD_02163 3.8e-44 yozN
NKPELAJD_02164 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
NKPELAJD_02165 9.8e-09 yocN
NKPELAJD_02166 5.9e-10 yocL
NKPELAJD_02167 9.5e-54 dksA T general stress protein
NKPELAJD_02169 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKPELAJD_02170 0.0 recQ 3.6.4.12 L DNA helicase
NKPELAJD_02171 1.6e-42 yocH CBM50 M COG1388 FOG LysM repeat
NKPELAJD_02173 1.1e-186 yocD 3.4.17.13 V peptidase S66
NKPELAJD_02174 1.9e-94 yocC
NKPELAJD_02175 5.6e-141 yocB J Protein required for attachment to host cells
NKPELAJD_02176 2.8e-91 yozB S membrane
NKPELAJD_02177 6e-120 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NKPELAJD_02178 3.4e-55 czrA K transcriptional
NKPELAJD_02179 3.2e-92 yobW
NKPELAJD_02180 1.9e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NKPELAJD_02181 1.3e-94 yobS K Transcriptional regulator
NKPELAJD_02182 3.5e-134 yobQ K helix_turn_helix, arabinose operon control protein
NKPELAJD_02183 5.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NKPELAJD_02184 2.6e-298 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NKPELAJD_02185 3.6e-55 S SMI1-KNR4 cell-wall
NKPELAJD_02186 3.9e-44
NKPELAJD_02187 1e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_02189 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKPELAJD_02190 4.3e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKPELAJD_02191 5.9e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
NKPELAJD_02192 1.9e-204 yoaB EGP Major facilitator Superfamily
NKPELAJD_02193 9.3e-141 yoxB
NKPELAJD_02194 2.2e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NKPELAJD_02195 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NKPELAJD_02196 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NKPELAJD_02197 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKPELAJD_02198 1.3e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKPELAJD_02199 8.7e-146 gltC K Transcriptional regulator
NKPELAJD_02200 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NKPELAJD_02201 1.9e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NKPELAJD_02202 1.1e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NKPELAJD_02203 2.8e-157 gltR1 K Transcriptional regulator
NKPELAJD_02204 6.3e-271 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKPELAJD_02205 6.7e-50 ybzH K Helix-turn-helix domain
NKPELAJD_02206 1.2e-200 ybcL EGP Major facilitator Superfamily
NKPELAJD_02207 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NKPELAJD_02208 1.8e-34 yoeD G Helix-turn-helix domain
NKPELAJD_02209 2.2e-96 L Integrase
NKPELAJD_02211 6.5e-119 L Phage integrase family
NKPELAJD_02212 4.3e-70
NKPELAJD_02214 7.8e-22 K Helix-turn-helix XRE-family like proteins
NKPELAJD_02216 3.7e-38 S Domain of unknown function (DUF771)
NKPELAJD_02218 4e-42 dnaC L IstB-like ATP binding protein
NKPELAJD_02221 7.6e-28
NKPELAJD_02224 4.7e-15 yqaO S Phage-like element PBSX protein XtrA
NKPELAJD_02227 8e-106 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
NKPELAJD_02229 3.4e-47
NKPELAJD_02231 1.1e-55 D nuclear chromosome segregation
NKPELAJD_02233 5.7e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
NKPELAJD_02234 1e-72 L Phage integrase family
NKPELAJD_02236 2.2e-47
NKPELAJD_02237 1.4e-68 S HNH endonuclease
NKPELAJD_02238 2.2e-22
NKPELAJD_02239 3.9e-87 S Phage terminase, small subunit
NKPELAJD_02240 3.7e-230 S Phage Terminase
NKPELAJD_02241 1e-10
NKPELAJD_02242 7.1e-239 S Phage portal protein
NKPELAJD_02243 1.2e-109 S peptidase activity
NKPELAJD_02244 4.2e-180 S capsid protein
NKPELAJD_02246 1.5e-24 S Phage gp6-like head-tail connector protein
NKPELAJD_02247 3.6e-15 S Phage head-tail joining protein
NKPELAJD_02248 4.6e-48 S Bacteriophage HK97-gp10, putative tail-component
NKPELAJD_02249 8.7e-31
NKPELAJD_02250 3.4e-61
NKPELAJD_02251 4.6e-23
NKPELAJD_02252 5.7e-11
NKPELAJD_02253 0.0 S peptidoglycan catabolic process
NKPELAJD_02254 7.1e-110 S Phage tail protein
NKPELAJD_02255 1.6e-225 NU Prophage endopeptidase tail
NKPELAJD_02256 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
NKPELAJD_02257 3.4e-69 S Domain of unknown function (DUF2479)
NKPELAJD_02260 6.9e-61 S Pfam:Phage_holin_4_1
NKPELAJD_02261 6.7e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKPELAJD_02263 2.6e-26 S SMI1 / KNR4 family
NKPELAJD_02264 4.4e-205 yobL S Bacterial EndoU nuclease
NKPELAJD_02265 5e-96 yoeB S IseA DL-endopeptidase inhibitor
NKPELAJD_02266 1e-246 yoeA V MATE efflux family protein
NKPELAJD_02267 2.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
NKPELAJD_02268 2.5e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NKPELAJD_02269 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_02270 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_02271 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_02272 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_02273 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
NKPELAJD_02274 4.1e-65 yngL S Protein of unknown function (DUF1360)
NKPELAJD_02275 2e-304 yngK T Glycosyl hydrolase-like 10
NKPELAJD_02276 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NKPELAJD_02277 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NKPELAJD_02278 1.2e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NKPELAJD_02279 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NKPELAJD_02280 2.5e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NKPELAJD_02281 5.8e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NKPELAJD_02282 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NKPELAJD_02283 4.1e-104 yngC S SNARE associated Golgi protein
NKPELAJD_02284 4.3e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NKPELAJD_02285 3.7e-72 yngA S membrane
NKPELAJD_02286 3e-147 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NKPELAJD_02287 1.7e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NKPELAJD_02288 1.2e-208 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NKPELAJD_02289 1.3e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NKPELAJD_02290 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NKPELAJD_02291 9.5e-225 bioI 1.14.14.46 C Cytochrome P450
NKPELAJD_02292 1.9e-256 yxjC EG COG2610 H gluconate symporter and related permeases
NKPELAJD_02293 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NKPELAJD_02294 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NKPELAJD_02295 1.8e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NKPELAJD_02296 5.3e-223 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKPELAJD_02297 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_02298 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_02299 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_02300 1.1e-289 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NKPELAJD_02301 5.1e-253 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
NKPELAJD_02302 7.6e-129 T Transcriptional regulatory protein, C terminal
NKPELAJD_02303 1.9e-232 T PhoQ Sensor
NKPELAJD_02304 2.8e-51 S Domain of unknown function (DUF4870)
NKPELAJD_02305 1.2e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NKPELAJD_02306 2.6e-216 S Platelet-activating factor acetylhydrolase, isoform II
NKPELAJD_02307 3.2e-11
NKPELAJD_02308 8.3e-63 V ABC transporter
NKPELAJD_02309 1.9e-82
NKPELAJD_02310 2e-302 yndJ S YndJ-like protein
NKPELAJD_02311 1.1e-78 yndH S Domain of unknown function (DUF4166)
NKPELAJD_02312 5.8e-157 yndG S DoxX-like family
NKPELAJD_02313 1.5e-223 exuT G Sugar (and other) transporter
NKPELAJD_02314 1.7e-182 kdgR_1 K transcriptional
NKPELAJD_02315 6e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKPELAJD_02316 1.9e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NKPELAJD_02317 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NKPELAJD_02318 6.9e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NKPELAJD_02319 1e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NKPELAJD_02320 1.6e-250 agcS E Sodium alanine symporter
NKPELAJD_02321 5.1e-41 ynfC
NKPELAJD_02322 6e-13
NKPELAJD_02323 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NKPELAJD_02324 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NKPELAJD_02325 1.5e-68 yccU S CoA-binding protein
NKPELAJD_02326 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NKPELAJD_02327 4.9e-50 yneR S Belongs to the HesB IscA family
NKPELAJD_02328 4.4e-54 yneQ
NKPELAJD_02329 8.3e-75 yneP S Thioesterase-like superfamily
NKPELAJD_02330 2.7e-33 tlp S Belongs to the Tlp family
NKPELAJD_02332 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NKPELAJD_02333 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NKPELAJD_02334 7.5e-15 sspO S Belongs to the SspO family
NKPELAJD_02335 2.3e-19 sspP S Belongs to the SspP family
NKPELAJD_02336 2.9e-63 hspX O Spore coat protein
NKPELAJD_02337 8.5e-75 yneK S Protein of unknown function (DUF2621)
NKPELAJD_02338 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NKPELAJD_02339 1.4e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NKPELAJD_02340 1.7e-125 ccdA O cytochrome c biogenesis protein
NKPELAJD_02341 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
NKPELAJD_02342 2.3e-28 yneF S UPF0154 protein
NKPELAJD_02343 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
NKPELAJD_02344 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NKPELAJD_02345 9.8e-33 ynzC S UPF0291 protein
NKPELAJD_02346 2.2e-111 yneB L resolvase
NKPELAJD_02347 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NKPELAJD_02348 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NKPELAJD_02349 7.1e-13 yoaW
NKPELAJD_02350 2.4e-72 yndM S Protein of unknown function (DUF2512)
NKPELAJD_02351 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
NKPELAJD_02352 1.6e-07
NKPELAJD_02353 8.7e-145 yndL S Replication protein
NKPELAJD_02354 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NKPELAJD_02355 0.0 yobO M Pectate lyase superfamily protein
NKPELAJD_02356 3.5e-94 yvgO
NKPELAJD_02357 2.5e-63 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NKPELAJD_02359 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
NKPELAJD_02360 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKPELAJD_02361 3.1e-118 ynaE S Domain of unknown function (DUF3885)
NKPELAJD_02364 1.9e-58
NKPELAJD_02365 9.8e-88 J Acetyltransferase (GNAT) domain
NKPELAJD_02366 3.1e-144 yoaP 3.1.3.18 K YoaP-like
NKPELAJD_02368 1.8e-43
NKPELAJD_02370 4.2e-16
NKPELAJD_02371 8.6e-11 ccmM S Bacterial transferase hexapeptide (six repeats)
NKPELAJD_02372 1.9e-186 adhP 1.1.1.1 C alcohol dehydrogenase
NKPELAJD_02373 5.4e-17
NKPELAJD_02376 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NKPELAJD_02377 2.7e-285 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
NKPELAJD_02378 3.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NKPELAJD_02379 2.1e-216 xylR GK ROK family
NKPELAJD_02380 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NKPELAJD_02381 9.6e-253 xynT G MFS/sugar transport protein
NKPELAJD_02382 1.2e-213 mrjp G Major royal jelly protein
NKPELAJD_02383 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
NKPELAJD_02384 4.3e-68 glnR K transcriptional
NKPELAJD_02385 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NKPELAJD_02386 2.7e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NKPELAJD_02387 5.1e-176 spoVK O stage V sporulation protein K
NKPELAJD_02388 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKPELAJD_02389 9e-110 ymaB S MutT family
NKPELAJD_02390 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKPELAJD_02391 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKPELAJD_02392 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NKPELAJD_02393 1.8e-20 ymzA
NKPELAJD_02394 8.5e-44
NKPELAJD_02395 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NKPELAJD_02396 9.6e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NKPELAJD_02397 4.1e-47 ymaF S YmaF family
NKPELAJD_02398 3.1e-48 ebrA P Small Multidrug Resistance protein
NKPELAJD_02399 5.2e-54 ebrB P Small Multidrug Resistance protein
NKPELAJD_02400 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
NKPELAJD_02401 4.1e-127 ymaC S Replication protein
NKPELAJD_02403 1.8e-256 aprX O Belongs to the peptidase S8 family
NKPELAJD_02404 1.4e-62 ymzB
NKPELAJD_02405 3.6e-118 yoaK S Membrane
NKPELAJD_02406 6.4e-78 nucB M Deoxyribonuclease NucA/NucB
NKPELAJD_02407 2.4e-231 cypA C Cytochrome P450
NKPELAJD_02408 0.0 pks13 HQ Beta-ketoacyl synthase
NKPELAJD_02409 0.0 dhbF IQ polyketide synthase
NKPELAJD_02410 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
NKPELAJD_02411 0.0 Q Polyketide synthase of type I
NKPELAJD_02412 0.0 rhiB IQ polyketide synthase
NKPELAJD_02413 1.9e-138 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NKPELAJD_02414 3.1e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
NKPELAJD_02415 8.2e-243 pksG 2.3.3.10 I synthase
NKPELAJD_02416 1.9e-34 acpK IQ Phosphopantetheine attachment site
NKPELAJD_02417 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKPELAJD_02418 1.1e-183 pksD Q Acyl transferase domain
NKPELAJD_02419 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKPELAJD_02420 2.2e-128 pksB 3.1.2.6 S Polyketide biosynthesis
NKPELAJD_02422 6.9e-31
NKPELAJD_02423 1.3e-68 L Belongs to the 'phage' integrase family
NKPELAJD_02424 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NKPELAJD_02425 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NKPELAJD_02426 1.7e-88 cotE S Spore coat protein
NKPELAJD_02427 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NKPELAJD_02428 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NKPELAJD_02429 6.7e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NKPELAJD_02430 1.5e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NKPELAJD_02431 1.2e-36 spoVS S Stage V sporulation protein S
NKPELAJD_02432 4.9e-153 ymdB S protein conserved in bacteria
NKPELAJD_02433 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
NKPELAJD_02434 5e-194 pbpX V Beta-lactamase
NKPELAJD_02435 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NKPELAJD_02436 1.7e-232 cinA 3.5.1.42 S Belongs to the CinA family
NKPELAJD_02437 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKPELAJD_02438 1.7e-125 ymfM S protein conserved in bacteria
NKPELAJD_02439 3.5e-143 ymfK S Protein of unknown function (DUF3388)
NKPELAJD_02440 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
NKPELAJD_02441 8.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NKPELAJD_02442 7.5e-244 ymfH S zinc protease
NKPELAJD_02443 1.2e-238 ymfF S Peptidase M16
NKPELAJD_02444 0.0 ydgH S drug exporters of the RND superfamily
NKPELAJD_02445 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_02446 2.4e-229 ymfD EGP Major facilitator Superfamily
NKPELAJD_02447 1.8e-133 ymfC K Transcriptional regulator
NKPELAJD_02448 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NKPELAJD_02449 6.3e-31 S YlzJ-like protein
NKPELAJD_02450 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NKPELAJD_02451 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NKPELAJD_02452 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NKPELAJD_02453 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NKPELAJD_02454 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NKPELAJD_02455 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NKPELAJD_02456 1.2e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NKPELAJD_02457 2.6e-42 ymxH S YlmC YmxH family
NKPELAJD_02458 3.6e-235 pepR S Belongs to the peptidase M16 family
NKPELAJD_02459 1.8e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NKPELAJD_02460 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NKPELAJD_02461 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NKPELAJD_02462 1e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NKPELAJD_02463 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NKPELAJD_02464 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NKPELAJD_02465 3.9e-44 ylxP S protein conserved in bacteria
NKPELAJD_02466 1.9e-300 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NKPELAJD_02467 1.8e-47 ylxQ J ribosomal protein
NKPELAJD_02468 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
NKPELAJD_02469 5.4e-206 nusA K Participates in both transcription termination and antitermination
NKPELAJD_02470 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
NKPELAJD_02471 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKPELAJD_02472 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NKPELAJD_02473 1.5e-233 rasP M zinc metalloprotease
NKPELAJD_02474 1.9e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NKPELAJD_02475 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
NKPELAJD_02476 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NKPELAJD_02477 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NKPELAJD_02478 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NKPELAJD_02479 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NKPELAJD_02480 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NKPELAJD_02481 2.7e-50 ylxL
NKPELAJD_02482 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKPELAJD_02483 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NKPELAJD_02484 5.4e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NKPELAJD_02485 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
NKPELAJD_02486 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NKPELAJD_02487 2.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NKPELAJD_02488 1.6e-155 flhG D Belongs to the ParA family
NKPELAJD_02489 3e-193 flhF N Flagellar biosynthesis regulator FlhF
NKPELAJD_02490 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NKPELAJD_02491 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NKPELAJD_02492 3.4e-130 fliR N Flagellar biosynthetic protein FliR
NKPELAJD_02493 2e-37 fliQ N Role in flagellar biosynthesis
NKPELAJD_02494 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NKPELAJD_02495 1.9e-110 fliZ N Flagellar biosynthesis protein, FliO
NKPELAJD_02496 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NKPELAJD_02497 9.6e-187 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NKPELAJD_02498 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NKPELAJD_02499 9.2e-58 fliL N Controls the rotational direction of flagella during chemotaxis
NKPELAJD_02500 4e-139 flgG N Flagellar basal body rod
NKPELAJD_02501 1.4e-72 flgD N Flagellar basal body rod modification protein
NKPELAJD_02502 1.2e-204 fliK N Flagellar hook-length control protein
NKPELAJD_02503 4.4e-48 ylxF S MgtE intracellular N domain
NKPELAJD_02504 4.5e-71 fliJ N Flagellar biosynthesis chaperone
NKPELAJD_02505 5.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NKPELAJD_02506 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NKPELAJD_02507 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NKPELAJD_02508 1.4e-263 fliF N The M ring may be actively involved in energy transduction
NKPELAJD_02509 2.5e-31 fliE N Flagellar hook-basal body
NKPELAJD_02510 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
NKPELAJD_02511 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NKPELAJD_02512 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NKPELAJD_02513 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NKPELAJD_02514 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NKPELAJD_02515 7.2e-172 xerC L tyrosine recombinase XerC
NKPELAJD_02516 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NKPELAJD_02517 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKPELAJD_02518 1.9e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NKPELAJD_02519 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NKPELAJD_02520 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NKPELAJD_02521 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NKPELAJD_02522 1.8e-306 ylqG
NKPELAJD_02523 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKPELAJD_02524 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NKPELAJD_02525 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NKPELAJD_02526 8.3e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NKPELAJD_02527 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NKPELAJD_02528 1.3e-61 ylqD S YlqD protein
NKPELAJD_02529 1.7e-35 ylqC S Belongs to the UPF0109 family
NKPELAJD_02530 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NKPELAJD_02531 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NKPELAJD_02532 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NKPELAJD_02533 1.5e-67 S Phosphotransferase enzyme family
NKPELAJD_02534 1.9e-17 S Phosphotransferase enzyme family
NKPELAJD_02535 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NKPELAJD_02536 0.0 smc D Required for chromosome condensation and partitioning
NKPELAJD_02537 2.6e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NKPELAJD_02538 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKPELAJD_02539 1.8e-128 IQ reductase
NKPELAJD_02540 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKPELAJD_02541 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NKPELAJD_02542 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NKPELAJD_02543 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NKPELAJD_02544 3.9e-154 sdaAA 4.3.1.17 E L-serine dehydratase
NKPELAJD_02545 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
NKPELAJD_02546 4.5e-305 yloV S kinase related to dihydroxyacetone kinase
NKPELAJD_02547 5.5e-59 asp S protein conserved in bacteria
NKPELAJD_02548 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NKPELAJD_02549 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
NKPELAJD_02550 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NKPELAJD_02551 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NKPELAJD_02552 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NKPELAJD_02553 1.7e-139 stp 3.1.3.16 T phosphatase
NKPELAJD_02554 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NKPELAJD_02555 4.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NKPELAJD_02556 3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NKPELAJD_02557 2.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NKPELAJD_02558 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKPELAJD_02559 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NKPELAJD_02560 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NKPELAJD_02561 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NKPELAJD_02562 1.5e-40 ylzA S Belongs to the UPF0296 family
NKPELAJD_02563 1.3e-154 yloC S stress-induced protein
NKPELAJD_02564 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NKPELAJD_02565 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NKPELAJD_02566 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
NKPELAJD_02567 2.2e-54 L COG2963 Transposase and inactivated derivatives
NKPELAJD_02568 5.9e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NKPELAJD_02569 5.8e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NKPELAJD_02570 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NKPELAJD_02571 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NKPELAJD_02572 2.9e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NKPELAJD_02573 3.9e-177 cysP P phosphate transporter
NKPELAJD_02574 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NKPELAJD_02576 3.8e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NKPELAJD_02577 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NKPELAJD_02578 1.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NKPELAJD_02579 1.3e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NKPELAJD_02580 0.0 carB 6.3.5.5 F Belongs to the CarB family
NKPELAJD_02581 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NKPELAJD_02582 2.7e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NKPELAJD_02583 9e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NKPELAJD_02584 8e-233 pyrP F Xanthine uracil
NKPELAJD_02585 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NKPELAJD_02586 3.9e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NKPELAJD_02587 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NKPELAJD_02588 3.4e-64 dksA T COG1734 DnaK suppressor protein
NKPELAJD_02589 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NKPELAJD_02590 8.9e-68 divIVA D Cell division initiation protein
NKPELAJD_02591 2.1e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NKPELAJD_02592 5.2e-41 yggT S membrane
NKPELAJD_02593 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NKPELAJD_02594 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NKPELAJD_02595 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NKPELAJD_02596 2.2e-38 ylmC S sporulation protein
NKPELAJD_02597 3.2e-255 argE 3.5.1.16 E Acetylornithine deacetylase
NKPELAJD_02598 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NKPELAJD_02599 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKPELAJD_02600 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKPELAJD_02601 1.9e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NKPELAJD_02602 0.0 bpr O COG1404 Subtilisin-like serine proteases
NKPELAJD_02603 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NKPELAJD_02604 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NKPELAJD_02605 8.7e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NKPELAJD_02606 5.6e-169 murB 1.3.1.98 M cell wall formation
NKPELAJD_02607 7.9e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NKPELAJD_02608 2.2e-185 spoVE D Belongs to the SEDS family
NKPELAJD_02609 1.2e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NKPELAJD_02610 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NKPELAJD_02611 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NKPELAJD_02612 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NKPELAJD_02613 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NKPELAJD_02614 2.9e-52 ftsL D Essential cell division protein
NKPELAJD_02615 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NKPELAJD_02616 8.9e-78 mraZ K Belongs to the MraZ family
NKPELAJD_02617 2.3e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NKPELAJD_02618 3.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NKPELAJD_02619 1.2e-88 ylbP K n-acetyltransferase
NKPELAJD_02620 4.5e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NKPELAJD_02621 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NKPELAJD_02622 7.8e-91 yceD S metal-binding, possibly nucleic acid-binding protein
NKPELAJD_02623 2.3e-229 ylbM S Belongs to the UPF0348 family
NKPELAJD_02624 2.1e-188 ylbL T Belongs to the peptidase S16 family
NKPELAJD_02625 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NKPELAJD_02626 4.4e-217 ylbJ S Sporulation integral membrane protein YlbJ
NKPELAJD_02627 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NKPELAJD_02628 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
NKPELAJD_02630 5.5e-43 ylbG S UPF0298 protein
NKPELAJD_02631 1.2e-71 ylbF S Belongs to the UPF0342 family
NKPELAJD_02632 3.3e-36 ylbE S YlbE-like protein
NKPELAJD_02633 6.5e-56 ylbD S Putative coat protein
NKPELAJD_02634 4.6e-199 ylbC S protein with SCP PR1 domains
NKPELAJD_02635 8.2e-73 ylbB T COG0517 FOG CBS domain
NKPELAJD_02636 8.5e-60 ylbA S YugN-like family
NKPELAJD_02637 1.1e-164 ctaG S cytochrome c oxidase
NKPELAJD_02638 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NKPELAJD_02639 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NKPELAJD_02640 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NKPELAJD_02641 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NKPELAJD_02642 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NKPELAJD_02643 3.8e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NKPELAJD_02644 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NKPELAJD_02645 3.2e-212 ftsW D Belongs to the SEDS family
NKPELAJD_02646 8.7e-44 ylaN S Belongs to the UPF0358 family
NKPELAJD_02647 7e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
NKPELAJD_02648 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NKPELAJD_02649 2.2e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NKPELAJD_02650 3.3e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKPELAJD_02651 1e-33 ylaI S protein conserved in bacteria
NKPELAJD_02652 1.3e-48 ylaH S YlaH-like protein
NKPELAJD_02653 0.0 typA T GTP-binding protein TypA
NKPELAJD_02654 6.7e-24 S Family of unknown function (DUF5325)
NKPELAJD_02655 6.3e-39 ylaE
NKPELAJD_02656 1.7e-13 sigC S Putative zinc-finger
NKPELAJD_02657 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NKPELAJD_02658 5.2e-83 ykzC S Acetyltransferase (GNAT) family
NKPELAJD_02659 2.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
NKPELAJD_02660 6.3e-24 ykzI
NKPELAJD_02661 4.9e-119 yktB S Belongs to the UPF0637 family
NKPELAJD_02662 1.6e-42 yktA S Belongs to the UPF0223 family
NKPELAJD_02663 1.3e-276 speA 4.1.1.19 E Arginine
NKPELAJD_02664 3.7e-140 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
NKPELAJD_02665 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NKPELAJD_02666 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKPELAJD_02667 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKPELAJD_02668 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKPELAJD_02669 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKPELAJD_02670 8.4e-212 V Beta-lactamase
NKPELAJD_02671 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
NKPELAJD_02672 0.0 Q Polyketide synthase of type I
NKPELAJD_02673 0.0 Q Polyketide synthase of type I
NKPELAJD_02674 0.0 Q Polyketide synthase of type I
NKPELAJD_02675 0.0 Q Polyketide synthase of type I
NKPELAJD_02676 0.0 Q polyketide synthase
NKPELAJD_02677 0.0 Q Polyketide synthase of type I
NKPELAJD_02678 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKPELAJD_02679 5.9e-104 recN L Putative cell-wall binding lipoprotein
NKPELAJD_02680 5.8e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NKPELAJD_02681 3.9e-147 ykrA S hydrolases of the HAD superfamily
NKPELAJD_02682 8.2e-31 ykzG S Belongs to the UPF0356 family
NKPELAJD_02683 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NKPELAJD_02684 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NKPELAJD_02685 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
NKPELAJD_02686 9.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NKPELAJD_02687 3.1e-245 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NKPELAJD_02688 2.1e-45 abrB K of stationary sporulation gene expression
NKPELAJD_02689 6.9e-184 mreB D Rod-share determining protein MreBH
NKPELAJD_02690 5.5e-12 S Uncharacterized protein YkpC
NKPELAJD_02691 5e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NKPELAJD_02692 1.3e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NKPELAJD_02693 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKPELAJD_02694 1.5e-37 ykoA
NKPELAJD_02695 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NKPELAJD_02696 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NKPELAJD_02697 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NKPELAJD_02698 1.1e-133 fruR K Transcriptional regulator
NKPELAJD_02699 2.7e-211 yknZ V ABC transporter (permease)
NKPELAJD_02700 6.1e-123 macB V ABC transporter, ATP-binding protein
NKPELAJD_02701 8.9e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKPELAJD_02702 1.4e-103 yknW S Yip1 domain
NKPELAJD_02703 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NKPELAJD_02704 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NKPELAJD_02705 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NKPELAJD_02706 1.3e-243 moeA 2.10.1.1 H molybdopterin
NKPELAJD_02707 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NKPELAJD_02708 4.1e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NKPELAJD_02709 1.1e-162 yknT
NKPELAJD_02710 4.5e-98 rok K Repressor of ComK
NKPELAJD_02711 1.1e-80 ykuV CO thiol-disulfide
NKPELAJD_02712 5.8e-141 ykuT M Mechanosensitive ion channel
NKPELAJD_02713 4.8e-38 ykuS S Belongs to the UPF0180 family
NKPELAJD_02714 3.8e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NKPELAJD_02715 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NKPELAJD_02716 2.5e-80 fld C Flavodoxin
NKPELAJD_02717 2.9e-170 ykuO
NKPELAJD_02718 3e-89 fld C Flavodoxin
NKPELAJD_02719 6e-168 ccpC K Transcriptional regulator
NKPELAJD_02720 1e-75 ykuL S CBS domain
NKPELAJD_02721 2.5e-26 ykzF S Antirepressor AbbA
NKPELAJD_02722 1.4e-92 ykuK S Ribonuclease H-like
NKPELAJD_02723 3.9e-37 ykuJ S protein conserved in bacteria
NKPELAJD_02724 1.5e-233 ykuI T Diguanylate phosphodiesterase
NKPELAJD_02726 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_02727 8.9e-156 ykuE S Metallophosphoesterase
NKPELAJD_02728 1.2e-88 ykuD S protein conserved in bacteria
NKPELAJD_02729 3e-240 ykuC EGP Major facilitator Superfamily
NKPELAJD_02730 1.4e-83 ykyB S YkyB-like protein
NKPELAJD_02731 1.8e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
NKPELAJD_02732 2.3e-09
NKPELAJD_02733 3.9e-215 patA 2.6.1.1 E Aminotransferase
NKPELAJD_02734 2.2e-289 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
NKPELAJD_02735 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NKPELAJD_02736 9.8e-114 ykwD J protein with SCP PR1 domains
NKPELAJD_02737 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NKPELAJD_02738 1.2e-264 mcpC NT chemotaxis protein
NKPELAJD_02739 9.5e-189 splB 4.1.99.14 L Spore photoproduct lyase
NKPELAJD_02740 6.1e-38 splA S Transcriptional regulator
NKPELAJD_02741 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NKPELAJD_02742 2.1e-39 ptsH G phosphocarrier protein HPr
NKPELAJD_02743 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKPELAJD_02744 5.1e-156 glcT K antiterminator
NKPELAJD_02745 7.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
NKPELAJD_02747 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NKPELAJD_02748 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NKPELAJD_02749 2.9e-87 stoA CO thiol-disulfide
NKPELAJD_02750 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKPELAJD_02751 2.4e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
NKPELAJD_02752 2.3e-27
NKPELAJD_02753 7.8e-25 ykvS S protein conserved in bacteria
NKPELAJD_02754 1.3e-44 ykvR S Protein of unknown function (DUF3219)
NKPELAJD_02755 3.4e-161 G Glycosyl hydrolases family 18
NKPELAJD_02756 1.3e-34 3.5.1.104 M LysM domain
NKPELAJD_02757 7.8e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
NKPELAJD_02758 1.1e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NKPELAJD_02759 7e-133 IQ Enoyl-(Acyl carrier protein) reductase
NKPELAJD_02760 5.1e-60 ykvN K Transcriptional regulator
NKPELAJD_02761 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NKPELAJD_02762 1.1e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NKPELAJD_02763 1.3e-78 queD 4.1.2.50, 4.2.3.12 H synthase
NKPELAJD_02764 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NKPELAJD_02765 1.5e-187
NKPELAJD_02766 9.2e-184 ykvI S membrane
NKPELAJD_02767 0.0 clpE O Belongs to the ClpA ClpB family
NKPELAJD_02768 1.1e-136 motA N flagellar motor
NKPELAJD_02769 2.5e-125 motB N Flagellar motor protein
NKPELAJD_02770 1.5e-77 ykvE K transcriptional
NKPELAJD_02771 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NKPELAJD_02772 3.4e-10 S Spo0E like sporulation regulatory protein
NKPELAJD_02773 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NKPELAJD_02774 2.2e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NKPELAJD_02775 4.4e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NKPELAJD_02776 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NKPELAJD_02777 8.3e-229 mtnE 2.6.1.83 E Aminotransferase
NKPELAJD_02778 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NKPELAJD_02779 2.5e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NKPELAJD_02780 5.3e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NKPELAJD_02782 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NKPELAJD_02783 0.0 kinE 2.7.13.3 T Histidine kinase
NKPELAJD_02784 2e-191 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NKPELAJD_02785 2.5e-22 ykzE
NKPELAJD_02786 7.2e-113 ydfR S Protein of unknown function (DUF421)
NKPELAJD_02787 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
NKPELAJD_02788 4.1e-156 htpX O Belongs to the peptidase M48B family
NKPELAJD_02789 7.8e-126 ykrK S Domain of unknown function (DUF1836)
NKPELAJD_02790 2.5e-26 sspD S small acid-soluble spore protein
NKPELAJD_02791 3.1e-119 rsgI S Anti-sigma factor N-terminus
NKPELAJD_02792 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKPELAJD_02793 1.2e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NKPELAJD_02794 4.1e-101 ykoX S membrane-associated protein
NKPELAJD_02795 9.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NKPELAJD_02796 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NKPELAJD_02797 2.2e-99 ykoP G polysaccharide deacetylase
NKPELAJD_02798 5e-81 ykoM K transcriptional
NKPELAJD_02799 3.1e-26 ykoL
NKPELAJD_02800 1.9e-16
NKPELAJD_02801 5.4e-53 tnrA K transcriptional
NKPELAJD_02802 2.2e-238 mgtE P Acts as a magnesium transporter
NKPELAJD_02804 3.9e-245 ydhD M Glycosyl hydrolase
NKPELAJD_02805 1.7e-97 ykoE S ABC-type cobalt transport system, permease component
NKPELAJD_02806 4.8e-304 P ABC transporter, ATP-binding protein
NKPELAJD_02807 2.1e-132 ykoC P Cobalt transport protein
NKPELAJD_02808 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKPELAJD_02809 8.6e-176 isp O Belongs to the peptidase S8 family
NKPELAJD_02810 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NKPELAJD_02811 4e-119 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NKPELAJD_02812 9.4e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
NKPELAJD_02813 1.1e-214 M Glycosyl transferase family 2
NKPELAJD_02815 4.2e-71 ohrB O Organic hydroperoxide resistance protein
NKPELAJD_02816 2.2e-85 ohrR K COG1846 Transcriptional regulators
NKPELAJD_02817 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NKPELAJD_02818 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NKPELAJD_02819 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKPELAJD_02820 1.5e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NKPELAJD_02821 3.4e-49 ykkD P Multidrug resistance protein
NKPELAJD_02822 9.4e-53 ykkC P Multidrug resistance protein
NKPELAJD_02823 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NKPELAJD_02824 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NKPELAJD_02825 3.2e-158 ykgA E Amidinotransferase
NKPELAJD_02826 2.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
NKPELAJD_02827 1.2e-182 ykfD E Belongs to the ABC transporter superfamily
NKPELAJD_02828 3.2e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NKPELAJD_02829 2.5e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NKPELAJD_02830 6.4e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NKPELAJD_02831 0.0 dppE E ABC transporter substrate-binding protein
NKPELAJD_02832 1.3e-190 dppD P Belongs to the ABC transporter superfamily
NKPELAJD_02833 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKPELAJD_02834 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKPELAJD_02835 6.5e-156 dppA E D-aminopeptidase
NKPELAJD_02837 3.1e-240 yubD P Major Facilitator Superfamily
NKPELAJD_02838 7.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKPELAJD_02840 1.4e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKPELAJD_02841 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NKPELAJD_02842 5e-184 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NKPELAJD_02843 5.2e-243 steT E amino acid
NKPELAJD_02844 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NKPELAJD_02845 7.5e-175 pit P phosphate transporter
NKPELAJD_02846 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NKPELAJD_02847 8.7e-23 spoIISB S Stage II sporulation protein SB
NKPELAJD_02848 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKPELAJD_02849 1.3e-38 xhlB S SPP1 phage holin
NKPELAJD_02850 8.7e-38 xhlA S Haemolysin XhlA
NKPELAJD_02851 9.6e-138 xepA
NKPELAJD_02852 1.9e-29 xkdX
NKPELAJD_02854 3.4e-92
NKPELAJD_02855 1.2e-26
NKPELAJD_02856 5.5e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NKPELAJD_02857 1.6e-90 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NKPELAJD_02858 7.2e-58 xkdS S Protein of unknown function (DUF2634)
NKPELAJD_02859 7.2e-32 xkdR S Protein of unknown function (DUF2577)
NKPELAJD_02860 1.4e-160 xkdQ 3.2.1.96 G NLP P60 protein
NKPELAJD_02861 8.7e-111 xkdP S Lysin motif
NKPELAJD_02862 4e-182 xkdO L Transglycosylase SLT domain
NKPELAJD_02863 3.4e-19
NKPELAJD_02864 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
NKPELAJD_02865 2e-74 xkdM S Phage tail tube protein
NKPELAJD_02866 2.2e-225 xkdK S Phage tail sheath C-terminal domain
NKPELAJD_02867 3.1e-14
NKPELAJD_02868 2.2e-57 xkdJ
NKPELAJD_02869 1.4e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
NKPELAJD_02870 5.5e-43 yqbH S Domain of unknown function (DUF3599)
NKPELAJD_02871 2.8e-45 yqbG S Protein of unknown function (DUF3199)
NKPELAJD_02872 1.7e-157 xkdG S Phage capsid family
NKPELAJD_02873 5.7e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
NKPELAJD_02874 4.6e-242 yqbA S portal protein
NKPELAJD_02875 2.7e-209 xtmB S phage terminase, large subunit
NKPELAJD_02876 1.2e-109 xtmA L phage terminase small subunit
NKPELAJD_02877 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NKPELAJD_02878 2e-10 yqaO S Phage-like element PBSX protein XtrA
NKPELAJD_02881 6.5e-153 xkdC L Bacterial dnaA protein
NKPELAJD_02883 1.2e-55 xre K Helix-turn-helix XRE-family like proteins
NKPELAJD_02884 1.3e-110 xkdA E IrrE N-terminal-like domain
NKPELAJD_02886 2.1e-111 yjqB S phage-related replication protein
NKPELAJD_02887 4.7e-61 yjqA S Bacterial PH domain
NKPELAJD_02888 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NKPELAJD_02890 4.9e-215 S response regulator aspartate phosphatase
NKPELAJD_02891 6.2e-79 yjoA S DinB family
NKPELAJD_02892 1.5e-130 MA20_18170 S membrane transporter protein
NKPELAJD_02893 3.8e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NKPELAJD_02894 1.5e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NKPELAJD_02895 3.4e-183 exuR K transcriptional
NKPELAJD_02896 6.6e-254 yjmB G symporter YjmB
NKPELAJD_02897 9.6e-277 uxaC 5.3.1.12 G glucuronate isomerase
NKPELAJD_02898 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NKPELAJD_02899 9.1e-66 yjlC S Protein of unknown function (DUF1641)
NKPELAJD_02900 1.8e-92 yjlB S Cupin domain
NKPELAJD_02901 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
NKPELAJD_02902 1.7e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
NKPELAJD_02903 3e-123 ybbM S transport system, permease component
NKPELAJD_02904 2.8e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NKPELAJD_02905 6.8e-29
NKPELAJD_02906 3.4e-222 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NKPELAJD_02907 7.2e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NKPELAJD_02908 4.3e-92 yjgD S Protein of unknown function (DUF1641)
NKPELAJD_02909 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
NKPELAJD_02910 5e-99 yjgB S Domain of unknown function (DUF4309)
NKPELAJD_02911 6.3e-47 T PhoQ Sensor
NKPELAJD_02912 7.5e-22 yjfB S Putative motility protein
NKPELAJD_02913 8.1e-106 yhiD S MgtC SapB transporter
NKPELAJD_02914 2.2e-51 K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_02915 3.5e-34
NKPELAJD_02916 4.9e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NKPELAJD_02917 5.7e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
NKPELAJD_02918 7.6e-282 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
NKPELAJD_02919 2.2e-48 lacF 2.7.1.207 G phosphotransferase system
NKPELAJD_02920 0.0 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKPELAJD_02921 4.9e-218 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NKPELAJD_02922 6.3e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NKPELAJD_02923 6.2e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NKPELAJD_02924 3.5e-221 ganA 3.2.1.89 G arabinogalactan
NKPELAJD_02925 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_02926 1.3e-249 yfjF EGP Belongs to the major facilitator superfamily
NKPELAJD_02927 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
NKPELAJD_02928 2.9e-165 bla 3.5.2.6 V beta-lactamase
NKPELAJD_02929 5.9e-59 E Glyoxalase-like domain
NKPELAJD_02932 3.5e-258 yobL S Bacterial EndoU nuclease
NKPELAJD_02933 1.5e-22
NKPELAJD_02934 1.2e-83
NKPELAJD_02935 8.7e-31
NKPELAJD_02936 2.1e-31 L Belongs to the 'phage' integrase family
NKPELAJD_02937 2.5e-64
NKPELAJD_02941 5.8e-93 M nucleic acid phosphodiester bond hydrolysis
NKPELAJD_02942 1.3e-30 S SMI1-KNR4 cell-wall
NKPELAJD_02943 8.1e-26
NKPELAJD_02945 1.3e-103 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NKPELAJD_02946 7.1e-58 S Pfam:Phage_holin_4_1
NKPELAJD_02951 1.1e-225 S peptidoglycan catabolic process
NKPELAJD_02952 1e-46
NKPELAJD_02953 2.7e-38 S Phage-related minor tail protein
NKPELAJD_02954 1e-19
NKPELAJD_02955 3.3e-25 S Phage tail assembly chaperone protein, TAC
NKPELAJD_02956 7.4e-33 S Phage tail tube protein
NKPELAJD_02957 7.7e-30 S Protein of unknown function (DUF3168)
NKPELAJD_02958 4.7e-38 S Bacteriophage HK97-gp10, putative tail-component
NKPELAJD_02959 1.6e-28 S Phage head-tail joining protein
NKPELAJD_02960 2.7e-27 S Phage gp6-like head-tail connector protein
NKPELAJD_02963 2.9e-54 gpG
NKPELAJD_02964 2.1e-43 S Phage minor structural protein GP20
NKPELAJD_02965 2.8e-91 S Phage Mu protein F like protein
NKPELAJD_02966 3.5e-120 S Phage portal protein, SPP1 Gp6-like
NKPELAJD_02967 4.9e-171 S Pfam:Terminase_3C
NKPELAJD_02968 1.4e-75 yqaS L DNA packaging
NKPELAJD_02970 5e-41 S Protein of unknown function (DUF2971)
NKPELAJD_02971 6e-13 K Transcriptional regulator
NKPELAJD_02972 1.7e-66 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NKPELAJD_02977 5e-17 yqaO S Phage-like element PBSX protein XtrA
NKPELAJD_02979 3.8e-59 rusA L Endodeoxyribonuclease RusA
NKPELAJD_02981 5.5e-122 xkdC L IstB-like ATP binding protein
NKPELAJD_02982 1.2e-73 3.1.3.16 L DnaD domain protein
NKPELAJD_02984 3.8e-68 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NKPELAJD_02985 1.2e-99
NKPELAJD_02989 3.2e-85
NKPELAJD_02990 3.4e-15 S Helix-turn-helix domain
NKPELAJD_02991 1.2e-19 K Helix-turn-helix XRE-family like proteins
NKPELAJD_02992 1.2e-45 xre K Helix-turn-helix XRE-family like proteins
NKPELAJD_02993 1.6e-07 S Short C-terminal domain
NKPELAJD_02994 1.3e-48 xkdA E IrrE N-terminal-like domain
NKPELAJD_02995 4.5e-177 L Belongs to the 'phage' integrase family
NKPELAJD_02997 2.6e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NKPELAJD_02998 1.3e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NKPELAJD_02999 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
NKPELAJD_03000 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NKPELAJD_03001 5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKPELAJD_03003 9.4e-36 K SpoVT / AbrB like domain
NKPELAJD_03004 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
NKPELAJD_03005 1.5e-124 S ABC-2 type transporter
NKPELAJD_03006 5.3e-141 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
NKPELAJD_03007 4.6e-36
NKPELAJD_03008 0.0 yjcD 3.6.4.12 L DNA helicase
NKPELAJD_03009 3.8e-38 spoVIF S Stage VI sporulation protein F
NKPELAJD_03012 2.5e-56 yjcA S Protein of unknown function (DUF1360)
NKPELAJD_03013 4.2e-57 cotV S Spore Coat Protein X and V domain
NKPELAJD_03014 1.1e-23 cotW
NKPELAJD_03015 4.4e-75 cotX S Spore Coat Protein X and V domain
NKPELAJD_03016 1.6e-90 cotY S Spore coat protein Z
NKPELAJD_03017 6.9e-80 cotZ S Spore coat protein
NKPELAJD_03018 6.6e-89 yjbX S Spore coat protein
NKPELAJD_03019 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NKPELAJD_03020 7.1e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NKPELAJD_03021 1.8e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NKPELAJD_03022 3.8e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NKPELAJD_03023 1.4e-30 thiS H Thiamine biosynthesis
NKPELAJD_03024 5.9e-213 thiO 1.4.3.19 E Glycine oxidase
NKPELAJD_03025 3.5e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NKPELAJD_03026 2.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NKPELAJD_03027 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NKPELAJD_03028 4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NKPELAJD_03029 1.2e-163 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NKPELAJD_03030 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKPELAJD_03031 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
NKPELAJD_03032 6e-61 yjbL S Belongs to the UPF0738 family
NKPELAJD_03033 1.2e-100 yjbK S protein conserved in bacteria
NKPELAJD_03034 3.8e-117 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NKPELAJD_03035 5.3e-71 yjbI S Bacterial-like globin
NKPELAJD_03036 8.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NKPELAJD_03037 5.8e-19
NKPELAJD_03038 0.0 pepF E oligoendopeptidase F
NKPELAJD_03039 1.1e-220 yjbF S Competence protein
NKPELAJD_03040 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NKPELAJD_03041 1.6e-109 yjbE P Integral membrane protein TerC family
NKPELAJD_03042 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NKPELAJD_03043 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKPELAJD_03044 1.2e-227 S Putative glycosyl hydrolase domain
NKPELAJD_03045 2.5e-172 oppF E Belongs to the ABC transporter superfamily
NKPELAJD_03046 2.7e-202 oppD P Belongs to the ABC transporter superfamily
NKPELAJD_03047 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKPELAJD_03048 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKPELAJD_03049 0.0 oppA E ABC transporter substrate-binding protein
NKPELAJD_03050 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NKPELAJD_03051 4.6e-140 EGP Transmembrane secretion effector
NKPELAJD_03052 3.8e-86 2.1.1.265 H Tellurite resistance protein TehB
NKPELAJD_03053 6.1e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKPELAJD_03054 7e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKPELAJD_03055 3.1e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NKPELAJD_03056 5.9e-188 appF E Belongs to the ABC transporter superfamily
NKPELAJD_03057 3.3e-183 appD P Belongs to the ABC transporter superfamily
NKPELAJD_03058 3.6e-148 yjaZ O Zn-dependent protease
NKPELAJD_03059 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKPELAJD_03060 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NKPELAJD_03061 5.9e-32 yjzB
NKPELAJD_03062 1.9e-26 comZ S ComZ
NKPELAJD_03063 1.9e-166 med S Transcriptional activator protein med
NKPELAJD_03064 1.5e-106 yjaV
NKPELAJD_03065 4.6e-137 yjaU I carboxylic ester hydrolase activity
NKPELAJD_03066 3.3e-23 yjzD S Protein of unknown function (DUF2929)
NKPELAJD_03067 1.2e-27 yjzC S YjzC-like protein
NKPELAJD_03068 4.6e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NKPELAJD_03069 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NKPELAJD_03070 8.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NKPELAJD_03071 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NKPELAJD_03072 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
NKPELAJD_03073 7.9e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NKPELAJD_03074 4.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NKPELAJD_03075 5.1e-85 norB G Major Facilitator Superfamily
NKPELAJD_03076 2.1e-271 yitY C D-arabinono-1,4-lactone oxidase
NKPELAJD_03077 5.9e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NKPELAJD_03078 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NKPELAJD_03079 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NKPELAJD_03080 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NKPELAJD_03081 3.5e-07
NKPELAJD_03082 4.4e-26 S Protein of unknown function (DUF3813)
NKPELAJD_03083 2.9e-81 ipi S Intracellular proteinase inhibitor
NKPELAJD_03084 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NKPELAJD_03085 1.9e-158 yitS S protein conserved in bacteria
NKPELAJD_03087 5.8e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NKPELAJD_03088 2.7e-230 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NKPELAJD_03089 3.7e-174 yufN S ABC transporter substrate-binding protein PnrA-like
NKPELAJD_03090 9e-161 cvfB S protein conserved in bacteria
NKPELAJD_03091 6.6e-55 yajQ S Belongs to the UPF0234 family
NKPELAJD_03092 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NKPELAJD_03093 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
NKPELAJD_03094 1.1e-70 mcbG S Pentapeptide repeats (9 copies)
NKPELAJD_03095 3.7e-90 yisT S DinB family
NKPELAJD_03096 5e-159 yisR K Transcriptional regulator
NKPELAJD_03097 3.3e-245 yisQ V Mate efflux family protein
NKPELAJD_03098 5.3e-133 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NKPELAJD_03099 0.0 asnO 6.3.5.4 E Asparagine synthase
NKPELAJD_03100 3.8e-96 yisN S Protein of unknown function (DUF2777)
NKPELAJD_03101 1.1e-59 yisL S UPF0344 protein
NKPELAJD_03102 7.8e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NKPELAJD_03103 5e-07 yisI S Spo0E like sporulation regulatory protein
NKPELAJD_03104 8.4e-34 gerPA S Spore germination protein
NKPELAJD_03105 6.2e-35 gerPB S cell differentiation
NKPELAJD_03106 1.4e-62 gerPC S Spore germination protein
NKPELAJD_03107 3.1e-23 gerPD S Spore germination protein
NKPELAJD_03108 8.1e-64 gerPE S Spore germination protein GerPE
NKPELAJD_03109 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
NKPELAJD_03110 5e-50 yisB V COG1403 Restriction endonuclease
NKPELAJD_03111 0.0 sbcC L COG0419 ATPase involved in DNA repair
NKPELAJD_03112 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NKPELAJD_03113 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NKPELAJD_03114 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NKPELAJD_03115 6.7e-125 ydfS S Protein of unknown function (DUF421)
NKPELAJD_03116 9.7e-94 yhjR S Rubrerythrin
NKPELAJD_03117 4.5e-109 K QacR-like protein, C-terminal region
NKPELAJD_03118 5.6e-209 blt EGP Major facilitator Superfamily
NKPELAJD_03119 4e-188 abrB S membrane
NKPELAJD_03120 1.7e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_03121 4.7e-274 yhjG CH FAD binding domain
NKPELAJD_03122 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NKPELAJD_03123 1.4e-110 yhjE S SNARE associated Golgi protein
NKPELAJD_03124 1.1e-59 yhjD
NKPELAJD_03125 1.4e-27 yhjC S Protein of unknown function (DUF3311)
NKPELAJD_03126 8.6e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKPELAJD_03127 3.3e-47 S Belongs to the UPF0145 family
NKPELAJD_03128 1.6e-42 yhjA S Excalibur calcium-binding domain
NKPELAJD_03129 1.2e-126 yrpD S Domain of unknown function, YrpD
NKPELAJD_03130 8.2e-93 mepB S MepB protein
NKPELAJD_03131 2.6e-64 frataxin S Domain of unknown function (DU1801)
NKPELAJD_03132 5.2e-65 frataxin S Domain of unknown function (DU1801)
NKPELAJD_03133 1.9e-109 comK K Competence transcription factor
NKPELAJD_03134 1.4e-31 yhzC S IDEAL
NKPELAJD_03135 8.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_03136 1.1e-297 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NKPELAJD_03137 9.1e-197 hemAT NT chemotaxis protein
NKPELAJD_03138 1e-88 bioY S BioY family
NKPELAJD_03139 7.3e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NKPELAJD_03140 5.5e-203 vraB 2.3.1.9 I Belongs to the thiolase family
NKPELAJD_03141 1.7e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NKPELAJD_03142 3.8e-154 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NKPELAJD_03143 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NKPELAJD_03144 5.1e-237 yhfN 3.4.24.84 O Peptidase M48
NKPELAJD_03145 1.3e-64 yhfM
NKPELAJD_03146 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NKPELAJD_03147 1.3e-111 yhfK GM NmrA-like family
NKPELAJD_03148 3.5e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
NKPELAJD_03149 9.9e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NKPELAJD_03150 7.9e-11 yhfH S YhfH-like protein
NKPELAJD_03151 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKPELAJD_03152 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NKPELAJD_03153 7.4e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NKPELAJD_03154 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
NKPELAJD_03155 3.2e-101 yhgD K Transcriptional regulator
NKPELAJD_03156 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NKPELAJD_03157 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NKPELAJD_03158 6.2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NKPELAJD_03159 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NKPELAJD_03160 1.9e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NKPELAJD_03161 2.6e-242 yhfA C membrane
NKPELAJD_03162 2.1e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NKPELAJD_03163 7.3e-124 ecsC S EcsC protein family
NKPELAJD_03164 8.5e-221 ecsB U ABC transporter
NKPELAJD_03165 1.1e-135 ecsA V transporter (ATP-binding protein)
NKPELAJD_03166 5.2e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NKPELAJD_03167 1.2e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NKPELAJD_03168 2.9e-77 trpP S Tryptophan transporter TrpP
NKPELAJD_03169 2e-17
NKPELAJD_03170 6.2e-39 yhaH S YtxH-like protein
NKPELAJD_03171 8.6e-113 hpr K Negative regulator of protease production and sporulation
NKPELAJD_03172 9.9e-55 yhaI S Protein of unknown function (DUF1878)
NKPELAJD_03173 7e-95 yhaK S Putative zincin peptidase
NKPELAJD_03174 3.3e-123 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NKPELAJD_03175 1.1e-31 yhaL S Sporulation protein YhaL
NKPELAJD_03176 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NKPELAJD_03177 0.0 yhaN L AAA domain
NKPELAJD_03178 7.7e-230 yhaO L DNA repair exonuclease
NKPELAJD_03179 1.5e-201 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NKPELAJD_03180 2.8e-14 S YhzD-like protein
NKPELAJD_03181 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
NKPELAJD_03183 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NKPELAJD_03184 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NKPELAJD_03185 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
NKPELAJD_03186 9.3e-294 hemZ H coproporphyrinogen III oxidase
NKPELAJD_03187 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
NKPELAJD_03188 1.3e-202 yhaZ L DNA alkylation repair enzyme
NKPELAJD_03189 4.4e-53 yheA S Belongs to the UPF0342 family
NKPELAJD_03190 7.2e-206 yheB S Belongs to the UPF0754 family
NKPELAJD_03191 4.8e-215 yheC HJ YheC/D like ATP-grasp
NKPELAJD_03192 7.2e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NKPELAJD_03193 1.7e-36 yheE S Family of unknown function (DUF5342)
NKPELAJD_03194 2.9e-28 sspB S spore protein
NKPELAJD_03196 7.4e-112 yheG GM NAD(P)H-binding
NKPELAJD_03197 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NKPELAJD_03198 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NKPELAJD_03200 2.1e-85 T universal stress protein
NKPELAJD_03201 1.2e-94 ymcC S Membrane
NKPELAJD_03202 4.6e-88 pksA K Transcriptional regulator
NKPELAJD_03203 4.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NKPELAJD_03204 1e-156 yheN G deacetylase
NKPELAJD_03205 6.5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NKPELAJD_03206 3.5e-205 yhdY M Mechanosensitive ion channel
NKPELAJD_03208 2e-129 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NKPELAJD_03209 2e-62 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NKPELAJD_03210 2.5e-51 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NKPELAJD_03211 1.1e-256 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NKPELAJD_03212 2.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKPELAJD_03213 7.7e-227 yhdR 2.6.1.1 E Aminotransferase
NKPELAJD_03214 4.3e-71 cueR K transcriptional
NKPELAJD_03215 2.8e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NKPELAJD_03216 1.3e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NKPELAJD_03217 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NKPELAJD_03218 6.6e-201 yhdL S Sigma factor regulator N-terminal
NKPELAJD_03219 8.1e-45 yhdK S Sigma-M inhibitor protein
NKPELAJD_03220 2e-143 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NKPELAJD_03221 9.1e-251 yhdG E amino acid
NKPELAJD_03222 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_03223 4.9e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
NKPELAJD_03224 5.8e-163 citR K Transcriptional regulator
NKPELAJD_03225 4.8e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NKPELAJD_03226 8.9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NKPELAJD_03227 1.2e-271 ycgB S Stage V sporulation protein R
NKPELAJD_03228 4.5e-256 ygxB M Conserved TM helix
NKPELAJD_03229 1.9e-74 nsrR K Transcriptional regulator
NKPELAJD_03230 2.6e-216 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NKPELAJD_03231 4e-53 yhdC S Protein of unknown function (DUF3889)
NKPELAJD_03232 2.5e-39 yhdB S YhdB-like protein
NKPELAJD_03233 8.8e-90 azr 1.7.1.6 S NADPH-dependent FMN reductase
NKPELAJD_03234 1e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKPELAJD_03235 1.7e-207 yhcY 2.7.13.3 T Histidine kinase
NKPELAJD_03236 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NKPELAJD_03237 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NKPELAJD_03238 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NKPELAJD_03239 4.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NKPELAJD_03240 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NKPELAJD_03241 1.9e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKPELAJD_03242 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NKPELAJD_03243 5.5e-124 yhcW 5.4.2.6 S hydrolase
NKPELAJD_03244 7.6e-68 yhcV S COG0517 FOG CBS domain
NKPELAJD_03245 2.9e-69 yhcU S Family of unknown function (DUF5365)
NKPELAJD_03246 2.8e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NKPELAJD_03247 4.8e-108 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NKPELAJD_03248 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
NKPELAJD_03249 5.8e-115 yhcQ M Spore coat protein
NKPELAJD_03250 3.3e-161 yhcP
NKPELAJD_03251 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKPELAJD_03252 3.5e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKPELAJD_03253 6.6e-193 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NKPELAJD_03254 4.2e-147 metQ M Belongs to the nlpA lipoprotein family
NKPELAJD_03255 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
NKPELAJD_03256 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NKPELAJD_03257 4.1e-167 yhcH V ABC transporter, ATP-binding protein
NKPELAJD_03258 1e-125 yhcG V ABC transporter, ATP-binding protein
NKPELAJD_03259 2.5e-62 yhcF K Transcriptional regulator
NKPELAJD_03260 9.6e-53
NKPELAJD_03261 3.8e-55 yhcC
NKPELAJD_03262 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
NKPELAJD_03263 8.4e-285 yhcA EGP Major facilitator Superfamily
NKPELAJD_03264 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
NKPELAJD_03265 4.6e-74 yhbI K DNA-binding transcription factor activity
NKPELAJD_03266 2.7e-216 yhbH S Belongs to the UPF0229 family
NKPELAJD_03267 0.0 prkA T Ser protein kinase
NKPELAJD_03269 1.3e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NKPELAJD_03270 2.8e-62 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NKPELAJD_03271 1e-108 yhbD K Protein of unknown function (DUF4004)
NKPELAJD_03272 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NKPELAJD_03273 5.5e-175 yhbB S Putative amidase domain
NKPELAJD_03274 1.9e-225 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NKPELAJD_03275 1.9e-112 yhzB S B3/4 domain
NKPELAJD_03277 3.3e-80 ygaO
NKPELAJD_03278 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKPELAJD_03279 3.8e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NKPELAJD_03280 3e-145 ssuC P ABC transporter (permease)
NKPELAJD_03281 9.1e-181 ssuA M Sulfonate ABC transporter
NKPELAJD_03282 4.2e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NKPELAJD_03283 2.2e-184 S Amidohydrolase
NKPELAJD_03284 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NKPELAJD_03285 7.6e-132 oppF3 E Belongs to the ABC transporter superfamily
NKPELAJD_03286 3.7e-134 oppD3 P Belongs to the ABC transporter superfamily
NKPELAJD_03287 2.4e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKPELAJD_03288 5.4e-138 appB P Binding-protein-dependent transport system inner membrane component
NKPELAJD_03289 5.4e-229 oppA5 E PFAM extracellular solute-binding protein family 5
NKPELAJD_03291 1.6e-265 ygaK C Berberine and berberine like
NKPELAJD_03292 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NKPELAJD_03293 3e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NKPELAJD_03294 1.6e-283 C Na+/H+ antiporter family
NKPELAJD_03298 1.6e-08
NKPELAJD_03301 2e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NKPELAJD_03302 7.3e-09
NKPELAJD_03303 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
NKPELAJD_03305 1.3e-139 E GDSL-like Lipase/Acylhydrolase family
NKPELAJD_03306 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKPELAJD_03307 4.4e-149 K Transcriptional regulator
NKPELAJD_03308 5.2e-125 azlC E AzlC protein
NKPELAJD_03309 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
NKPELAJD_03310 7.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NKPELAJD_03311 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NKPELAJD_03312 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NKPELAJD_03313 7.1e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
NKPELAJD_03314 2.3e-231 acuC BQ histone deacetylase
NKPELAJD_03315 2e-118 motS N Flagellar motor protein
NKPELAJD_03316 5.1e-145 motA N flagellar motor
NKPELAJD_03317 1.4e-181 ccpA K catabolite control protein A
NKPELAJD_03318 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NKPELAJD_03319 2.9e-43 ytxJ O Protein of unknown function (DUF2847)
NKPELAJD_03320 1.7e-16 ytxH S COG4980 Gas vesicle protein
NKPELAJD_03321 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NKPELAJD_03322 2.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NKPELAJD_03323 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NKPELAJD_03324 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NKPELAJD_03325 1.4e-147 ytpQ S Belongs to the UPF0354 family
NKPELAJD_03326 2.7e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NKPELAJD_03327 1.1e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NKPELAJD_03328 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NKPELAJD_03329 1.7e-51 ytzB S small secreted protein
NKPELAJD_03330 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NKPELAJD_03331 1.5e-163 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NKPELAJD_03332 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NKPELAJD_03333 3.5e-45 ytzH S YtzH-like protein
NKPELAJD_03334 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
NKPELAJD_03335 1.4e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NKPELAJD_03336 2.1e-166 ytlQ
NKPELAJD_03337 9.8e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NKPELAJD_03338 5.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NKPELAJD_03339 5.1e-270 pepV 3.5.1.18 E Dipeptidase
NKPELAJD_03340 4.1e-229 pbuO S permease
NKPELAJD_03341 1.1e-217 ythQ U Bacterial ABC transporter protein EcsB
NKPELAJD_03342 4.9e-128 ythP V ABC transporter
NKPELAJD_03343 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NKPELAJD_03344 6.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NKPELAJD_03345 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKPELAJD_03346 7.4e-236 ytfP S HI0933-like protein
NKPELAJD_03347 4.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NKPELAJD_03348 9e-26 yteV S Sporulation protein Cse60
NKPELAJD_03349 5.7e-186 msmR K Transcriptional regulator
NKPELAJD_03350 7.5e-244 msmE G Bacterial extracellular solute-binding protein
NKPELAJD_03351 2.6e-166 amyD G Binding-protein-dependent transport system inner membrane component
NKPELAJD_03352 1.4e-142 amyC P ABC transporter (permease)
NKPELAJD_03353 4.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NKPELAJD_03354 6e-85 M Acetyltransferase (GNAT) domain
NKPELAJD_03355 5.6e-52 ytwF P Sulfurtransferase
NKPELAJD_03356 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NKPELAJD_03357 1.2e-52 ytvB S Protein of unknown function (DUF4257)
NKPELAJD_03358 6.6e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NKPELAJD_03359 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
NKPELAJD_03360 1.1e-40 L transposase activity
NKPELAJD_03361 7.3e-209 yttB EGP Major facilitator Superfamily
NKPELAJD_03362 4.1e-130 ywaF S Integral membrane protein
NKPELAJD_03363 0.0 bceB V ABC transporter (permease)
NKPELAJD_03364 9.8e-135 bceA V ABC transporter, ATP-binding protein
NKPELAJD_03365 9.2e-170 T PhoQ Sensor
NKPELAJD_03366 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_03367 1.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NKPELAJD_03368 1.3e-125 ytrE V ABC transporter, ATP-binding protein
NKPELAJD_03369 4.4e-159
NKPELAJD_03370 2.9e-171 P ABC-2 family transporter protein
NKPELAJD_03371 4e-168 S ABC-2 family transporter protein
NKPELAJD_03372 4.2e-161 ytrB P abc transporter atp-binding protein
NKPELAJD_03373 3.9e-66 ytrA K GntR family transcriptional regulator
NKPELAJD_03375 6.2e-39 ytzC S Protein of unknown function (DUF2524)
NKPELAJD_03376 1e-188 K helix_turn_helix, Arsenical Resistance Operon Repressor
NKPELAJD_03377 4.3e-284 norB EGP COG0477 Permeases of the major facilitator superfamily
NKPELAJD_03378 1.8e-189 yhcC S Fe-S oxidoreductase
NKPELAJD_03379 1.9e-106 ytqB J Putative rRNA methylase
NKPELAJD_03381 8.6e-145 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
NKPELAJD_03382 9.9e-213 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NKPELAJD_03383 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
NKPELAJD_03384 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NKPELAJD_03385 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NKPELAJD_03386 0.0 asnB 6.3.5.4 E Asparagine synthase
NKPELAJD_03387 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NKPELAJD_03388 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NKPELAJD_03389 1.6e-38 ytmB S Protein of unknown function (DUF2584)
NKPELAJD_03390 6.1e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NKPELAJD_03391 3.3e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NKPELAJD_03392 3.2e-144 ytlC P ABC transporter
NKPELAJD_03393 5.8e-125 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NKPELAJD_03394 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NKPELAJD_03395 1.7e-61 ytkC S Bacteriophage holin family
NKPELAJD_03396 1.6e-76 dps P Belongs to the Dps family
NKPELAJD_03398 1.8e-75 ytkA S YtkA-like
NKPELAJD_03399 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NKPELAJD_03400 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NKPELAJD_03401 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NKPELAJD_03402 3e-40 rpmE2 J Ribosomal protein L31
NKPELAJD_03403 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
NKPELAJD_03404 5.9e-183 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NKPELAJD_03405 2.3e-24 S Domain of Unknown Function (DUF1540)
NKPELAJD_03406 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NKPELAJD_03407 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NKPELAJD_03408 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NKPELAJD_03409 1.7e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NKPELAJD_03410 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NKPELAJD_03411 2.3e-270 menF 5.4.4.2 HQ Isochorismate synthase
NKPELAJD_03412 2e-132 dksA T COG1734 DnaK suppressor protein
NKPELAJD_03413 4.5e-77 tspO T membrane
NKPELAJD_03421 7.8e-08
NKPELAJD_03427 1.3e-09
NKPELAJD_03434 1.6e-08
NKPELAJD_03439 2.2e-30 csfB S Inhibitor of sigma-G Gin
NKPELAJD_03440 8.6e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NKPELAJD_03441 1.2e-189 yaaN P Belongs to the TelA family
NKPELAJD_03442 6.2e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NKPELAJD_03443 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NKPELAJD_03444 7.5e-55 yaaQ S protein conserved in bacteria
NKPELAJD_03445 1.2e-71 yaaR S protein conserved in bacteria
NKPELAJD_03446 1.3e-182 holB 2.7.7.7 L DNA polymerase III
NKPELAJD_03447 8.8e-145 yaaT S stage 0 sporulation protein
NKPELAJD_03448 7.7e-37 yabA L Involved in initiation control of chromosome replication
NKPELAJD_03449 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NKPELAJD_03450 4.7e-48 yazA L endonuclease containing a URI domain
NKPELAJD_03451 5.3e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NKPELAJD_03452 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NKPELAJD_03453 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKPELAJD_03454 2e-143 tatD L hydrolase, TatD
NKPELAJD_03455 1.8e-232 rpfB GH23 T protein conserved in bacteria
NKPELAJD_03456 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NKPELAJD_03457 1.1e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NKPELAJD_03458 8.4e-146 yabG S peptidase
NKPELAJD_03459 7.8e-39 veg S protein conserved in bacteria
NKPELAJD_03460 2.9e-27 sspF S DNA topological change
NKPELAJD_03461 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NKPELAJD_03462 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NKPELAJD_03463 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NKPELAJD_03464 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NKPELAJD_03465 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NKPELAJD_03466 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NKPELAJD_03467 2e-106 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NKPELAJD_03468 9.4e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NKPELAJD_03469 3.7e-40 yabK S Peptide ABC transporter permease
NKPELAJD_03470 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NKPELAJD_03471 6.2e-91 spoVT K stage V sporulation protein
NKPELAJD_03472 2e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKPELAJD_03473 2.3e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NKPELAJD_03474 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NKPELAJD_03475 1.9e-49 yabP S Sporulation protein YabP
NKPELAJD_03476 5.8e-104 yabQ S spore cortex biosynthesis protein
NKPELAJD_03477 4.1e-57 divIC D Septum formation initiator
NKPELAJD_03478 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NKPELAJD_03481 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NKPELAJD_03482 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
NKPELAJD_03483 4.7e-185 KLT serine threonine protein kinase
NKPELAJD_03484 1.1e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NKPELAJD_03485 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NKPELAJD_03486 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NKPELAJD_03487 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NKPELAJD_03488 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NKPELAJD_03489 3.1e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NKPELAJD_03490 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NKPELAJD_03491 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NKPELAJD_03492 1.4e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NKPELAJD_03493 1.2e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NKPELAJD_03494 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NKPELAJD_03495 2.9e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NKPELAJD_03496 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NKPELAJD_03497 4.5e-29 yazB K transcriptional
NKPELAJD_03498 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKPELAJD_03499 9.3e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NKPELAJD_03500 5e-221 glcP G Major Facilitator Superfamily
NKPELAJD_03501 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKPELAJD_03502 1.1e-178 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
NKPELAJD_03503 7.6e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
NKPELAJD_03504 6e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NKPELAJD_03505 1.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
NKPELAJD_03506 5.1e-115 ybbA S Putative esterase
NKPELAJD_03507 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_03508 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_03509 2e-172 feuA P Iron-uptake system-binding protein
NKPELAJD_03510 2.2e-311 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NKPELAJD_03511 1.2e-238 ybbC 3.2.1.52 S protein conserved in bacteria
NKPELAJD_03512 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NKPELAJD_03513 1.5e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NKPELAJD_03514 2.7e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKPELAJD_03515 2.8e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NKPELAJD_03516 1.1e-86 ybbJ J acetyltransferase
NKPELAJD_03517 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NKPELAJD_03523 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NKPELAJD_03524 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NKPELAJD_03525 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NKPELAJD_03526 1.3e-223 ybbR S protein conserved in bacteria
NKPELAJD_03527 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NKPELAJD_03528 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NKPELAJD_03529 3.8e-154 V ATPases associated with a variety of cellular activities
NKPELAJD_03530 8.3e-106 S ABC-2 family transporter protein
NKPELAJD_03531 7e-100 ybdN
NKPELAJD_03532 1.9e-132 ybdO S Domain of unknown function (DUF4885)
NKPELAJD_03533 1.5e-163 dkgB S Aldo/keto reductase family
NKPELAJD_03534 1e-93 yxaC M effector of murein hydrolase
NKPELAJD_03535 6.9e-52 S LrgA family
NKPELAJD_03536 8.8e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_03537 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NKPELAJD_03538 1.1e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NKPELAJD_03539 1.8e-103 T Histidine kinase
NKPELAJD_03540 4.9e-82 KT helix_turn_helix, Lux Regulon
NKPELAJD_03541 3.5e-134 V ABC transporter, ATP-binding protein
NKPELAJD_03542 3.4e-145 V ABC-2 type transporter
NKPELAJD_03543 6e-123 V ABC-2 type transporter
NKPELAJD_03544 4.4e-14
NKPELAJD_03545 9.6e-60 bacT Q Thioesterase domain
NKPELAJD_03546 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
NKPELAJD_03547 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
NKPELAJD_03548 4.6e-121 fabD 2.3.1.39 I PFAM Acyl transferase
NKPELAJD_03549 0.0 Q Beta-ketoacyl synthase
NKPELAJD_03550 0.0 Q Polyketide synthase modules and related proteins
NKPELAJD_03551 1.5e-102 Q Flavin containing amine oxidoreductase
NKPELAJD_03552 0.0 Q TIGRFAM amino acid adenylation domain
NKPELAJD_03553 3.5e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
NKPELAJD_03554 9.1e-78 S Domain of unknown function (DUF4879)
NKPELAJD_03555 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NKPELAJD_03556 1.4e-46 yqeB
NKPELAJD_03557 9.2e-40 ybyB
NKPELAJD_03558 2.5e-292 ybeC E amino acid
NKPELAJD_03559 2.4e-45 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NKPELAJD_03560 1.9e-55
NKPELAJD_03561 3.4e-15 S Protein of unknown function (DUF2651)
NKPELAJD_03562 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NKPELAJD_03563 3e-259 glpT G -transporter
NKPELAJD_03564 1.3e-16 S Protein of unknown function (DUF2651)
NKPELAJD_03565 4.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NKPELAJD_03567 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NKPELAJD_03568 1.3e-30
NKPELAJD_03569 1.2e-82 K Helix-turn-helix XRE-family like proteins
NKPELAJD_03570 1.1e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
NKPELAJD_03571 1.8e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NKPELAJD_03572 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKPELAJD_03573 1.9e-86 ybfM S SNARE associated Golgi protein
NKPELAJD_03574 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NKPELAJD_03575 1.2e-42 ybfN
NKPELAJD_03576 8.6e-192 yceA S Belongs to the UPF0176 family
NKPELAJD_03577 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKPELAJD_03578 1.9e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NKPELAJD_03579 1.8e-257 mmuP E amino acid
NKPELAJD_03580 7.1e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NKPELAJD_03581 2.7e-258 agcS E Sodium alanine symporter
NKPELAJD_03582 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
NKPELAJD_03583 1.5e-212 phoQ 2.7.13.3 T Histidine kinase
NKPELAJD_03584 1.9e-172 glnL T Regulator
NKPELAJD_03585 2.7e-29 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NKPELAJD_03586 9.8e-20 L Transposase
NKPELAJD_03587 1.2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKPELAJD_03588 9.6e-112 ydfN C nitroreductase
NKPELAJD_03589 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NKPELAJD_03590 1.5e-62 mhqP S DoxX
NKPELAJD_03591 1.6e-55 traF CO Thioredoxin
NKPELAJD_03592 5.6e-62 ycbP S Protein of unknown function (DUF2512)
NKPELAJD_03593 5.1e-80 sleB 3.5.1.28 M Cell wall
NKPELAJD_03594 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NKPELAJD_03595 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NKPELAJD_03596 3e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKPELAJD_03597 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NKPELAJD_03598 3.1e-209 ycbU E Selenocysteine lyase
NKPELAJD_03599 6.9e-238 lmrB EGP the major facilitator superfamily
NKPELAJD_03600 1.2e-100 yxaF K Transcriptional regulator
NKPELAJD_03601 1.2e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NKPELAJD_03602 3.4e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NKPELAJD_03603 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
NKPELAJD_03604 6.2e-171 yccK C Aldo keto reductase
NKPELAJD_03605 6.2e-177 ycdA S Domain of unknown function (DUF5105)
NKPELAJD_03606 1.6e-263 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NKPELAJD_03607 2.8e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NKPELAJD_03608 9e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
NKPELAJD_03609 4.6e-189 S response regulator aspartate phosphatase
NKPELAJD_03610 7.3e-141 IQ Enoyl-(Acyl carrier protein) reductase
NKPELAJD_03611 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NKPELAJD_03612 3.5e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
NKPELAJD_03613 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NKPELAJD_03614 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NKPELAJD_03615 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKPELAJD_03616 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NKPELAJD_03617 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
NKPELAJD_03618 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
NKPELAJD_03619 9.7e-138 terC P Protein of unknown function (DUF475)
NKPELAJD_03620 0.0 yceG S Putative component of 'biosynthetic module'
NKPELAJD_03621 8.7e-193 yceH P Belongs to the TelA family
NKPELAJD_03622 1.2e-214 naiP P Uncharacterised MFS-type transporter YbfB
NKPELAJD_03623 3.9e-229 proV 3.6.3.32 E glycine betaine
NKPELAJD_03624 1.6e-138 opuAB P glycine betaine
NKPELAJD_03625 3.1e-164 opuAC E glycine betaine
NKPELAJD_03626 1.7e-212 amhX S amidohydrolase
NKPELAJD_03627 3.1e-230 ycgA S Membrane
NKPELAJD_03628 4.1e-81 ycgB
NKPELAJD_03629 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NKPELAJD_03630 1.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NKPELAJD_03631 8.1e-261 mdr EGP Major facilitator Superfamily
NKPELAJD_03632 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
NKPELAJD_03633 4.7e-114 ycgF E Lysine exporter protein LysE YggA
NKPELAJD_03634 1.9e-149 yqcI S YqcI/YcgG family
NKPELAJD_03635 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NKPELAJD_03636 7.6e-114 ycgI S Domain of unknown function (DUF1989)
NKPELAJD_03637 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NKPELAJD_03639 2.4e-84 tmrB S AAA domain
NKPELAJD_03640 3.1e-16 tmrB S AAA domain
NKPELAJD_03641 5.6e-149 4.2.1.118 G Xylose isomerase-like TIM barrel
NKPELAJD_03642 1.4e-232 G COG0477 Permeases of the major facilitator superfamily
NKPELAJD_03643 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NKPELAJD_03644 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NKPELAJD_03645 1.5e-146 ycgL S Predicted nucleotidyltransferase
NKPELAJD_03646 2.3e-170 ycgM E Proline dehydrogenase
NKPELAJD_03647 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NKPELAJD_03648 9.7e-239 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKPELAJD_03649 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NKPELAJD_03650 1.3e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NKPELAJD_03651 1.7e-281 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NKPELAJD_03652 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
NKPELAJD_03653 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NKPELAJD_03654 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKPELAJD_03655 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NKPELAJD_03656 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
NKPELAJD_03657 7.8e-227 yciC S GTPases (G3E family)
NKPELAJD_03658 3.9e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NKPELAJD_03659 1.2e-73 yckC S membrane
NKPELAJD_03660 2.2e-51 S Protein of unknown function (DUF2680)
NKPELAJD_03661 6.1e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NKPELAJD_03662 1.8e-66 nin S Competence protein J (ComJ)
NKPELAJD_03663 1.2e-76 nucA M Deoxyribonuclease NucA/NucB
NKPELAJD_03664 1.3e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NKPELAJD_03665 2.5e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NKPELAJD_03666 6.3e-63 hxlR K transcriptional
NKPELAJD_03667 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_03668 1.1e-83 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_03669 2.5e-71 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_03670 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKPELAJD_03671 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NKPELAJD_03672 2e-140 srfAD Q thioesterase
NKPELAJD_03673 3.6e-249 bamJ E Aminotransferase class I and II
NKPELAJD_03674 3.8e-64 S YcxB-like protein
NKPELAJD_03675 6e-169 ycxC EG EamA-like transporter family
NKPELAJD_03676 3.1e-245 ycxD K GntR family transcriptional regulator
NKPELAJD_03677 1e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NKPELAJD_03678 4.1e-110 yczE S membrane
NKPELAJD_03679 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NKPELAJD_03680 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
NKPELAJD_03681 1.6e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NKPELAJD_03682 1.1e-158 bsdA K LysR substrate binding domain
NKPELAJD_03683 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NKPELAJD_03684 2.4e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NKPELAJD_03685 2e-38 bsdD 4.1.1.61 S response to toxic substance
NKPELAJD_03686 1.3e-76 yclD
NKPELAJD_03687 1.2e-269 dtpT E amino acid peptide transporter
NKPELAJD_03688 5.2e-280 yclG M Pectate lyase superfamily protein
NKPELAJD_03690 4.1e-295 gerKA EG Spore germination protein
NKPELAJD_03691 5.5e-236 gerKC S spore germination
NKPELAJD_03692 8.7e-196 gerKB F Spore germination protein
NKPELAJD_03693 7.5e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKPELAJD_03694 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKPELAJD_03695 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
NKPELAJD_03696 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
NKPELAJD_03697 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NKPELAJD_03698 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
NKPELAJD_03699 3.2e-253 yxeQ S MmgE/PrpD family
NKPELAJD_03700 5.6e-121 yclH P ABC transporter
NKPELAJD_03701 3.6e-223 yclI V ABC transporter (permease) YclI
NKPELAJD_03702 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKPELAJD_03703 1.1e-262 T PhoQ Sensor
NKPELAJD_03704 1.9e-81 S aspartate phosphatase
NKPELAJD_03706 5.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
NKPELAJD_03707 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_03708 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKPELAJD_03709 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NKPELAJD_03710 2.1e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NKPELAJD_03711 2.3e-249 ycnB EGP Major facilitator Superfamily
NKPELAJD_03712 2.7e-152 ycnC K Transcriptional regulator
NKPELAJD_03713 8.8e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
NKPELAJD_03714 1e-44 ycnE S Monooxygenase
NKPELAJD_03715 1.1e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NKPELAJD_03716 3e-262 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKPELAJD_03717 5.3e-221 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKPELAJD_03718 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKPELAJD_03719 3.6e-149 glcU U Glucose uptake
NKPELAJD_03720 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_03721 1.7e-97 ycnI S protein conserved in bacteria
NKPELAJD_03722 4.7e-299 ycnJ P protein, homolog of Cu resistance protein CopC
NKPELAJD_03723 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NKPELAJD_03724 1.6e-55
NKPELAJD_03725 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NKPELAJD_03726 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NKPELAJD_03727 1.3e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NKPELAJD_03728 1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NKPELAJD_03730 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NKPELAJD_03731 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
NKPELAJD_03732 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NKPELAJD_03733 3.9e-150 ycsI S Belongs to the D-glutamate cyclase family
NKPELAJD_03734 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NKPELAJD_03735 3.2e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NKPELAJD_03736 4e-131 kipR K Transcriptional regulator
NKPELAJD_03737 9.3e-118 ycsK E anatomical structure formation involved in morphogenesis
NKPELAJD_03739 5.1e-56 yczJ S biosynthesis
NKPELAJD_03740 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NKPELAJD_03741 1.5e-174 ydhF S Oxidoreductase
NKPELAJD_03742 0.0 mtlR K transcriptional regulator, MtlR
NKPELAJD_03743 6.5e-287 ydaB IQ acyl-CoA ligase
NKPELAJD_03744 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKPELAJD_03745 4.6e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NKPELAJD_03746 1.2e-114 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NKPELAJD_03747 1.4e-77 ydaG 1.4.3.5 S general stress protein
NKPELAJD_03748 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NKPELAJD_03749 1.3e-47 ydzA EGP Major facilitator Superfamily
NKPELAJD_03750 4.3e-74 lrpC K Transcriptional regulator
NKPELAJD_03751 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKPELAJD_03752 1.1e-200 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NKPELAJD_03753 1.3e-146 ydaK T Diguanylate cyclase, GGDEF domain
NKPELAJD_03754 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NKPELAJD_03755 8.5e-232 ydaM M Glycosyl transferase family group 2
NKPELAJD_03756 0.0 ydaN S Bacterial cellulose synthase subunit
NKPELAJD_03758 0.0 ydaO E amino acid
NKPELAJD_03759 8e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NKPELAJD_03760 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NKPELAJD_03761 7.5e-66 K acetyltransferase
NKPELAJD_03763 9.5e-15
NKPELAJD_03765 1.3e-39 yqbQ 3.2.1.96 G NLP P60 protein
NKPELAJD_03766 5.9e-34 xkdR S Protein of unknown function (DUF2577)
NKPELAJD_03767 2.5e-108 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NKPELAJD_03768 7.5e-16 xkdS S Protein of unknown function (DUF2634)
NKPELAJD_03769 6.2e-21 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NKPELAJD_03771 2.5e-79
NKPELAJD_03772 5.6e-98
NKPELAJD_03773 2.1e-39
NKPELAJD_03774 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
NKPELAJD_03776 1.9e-33 ydaT
NKPELAJD_03777 2.4e-71 yvaD S Family of unknown function (DUF5360)
NKPELAJD_03778 4.1e-54 yvaE P Small Multidrug Resistance protein
NKPELAJD_03779 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NKPELAJD_03780 1.7e-57 ydbB G Cupin domain
NKPELAJD_03781 1.4e-62 ydbC S Domain of unknown function (DUF4937
NKPELAJD_03782 2.5e-155 ydbD P Catalase
NKPELAJD_03783 7.1e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NKPELAJD_03784 2.1e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NKPELAJD_03785 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NKPELAJD_03786 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKPELAJD_03787 3.2e-160 ydbI S AI-2E family transporter
NKPELAJD_03788 5e-173 ydbJ V ABC transporter, ATP-binding protein
NKPELAJD_03789 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NKPELAJD_03790 2.1e-52 ydbL
NKPELAJD_03791 4.5e-205 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NKPELAJD_03792 1.5e-10 S Fur-regulated basic protein B
NKPELAJD_03793 5.8e-09 S Fur-regulated basic protein A
NKPELAJD_03794 1.1e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKPELAJD_03795 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NKPELAJD_03796 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NKPELAJD_03797 6.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NKPELAJD_03798 5.3e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NKPELAJD_03799 2.1e-82 ydbS S Bacterial PH domain
NKPELAJD_03800 7.5e-264 ydbT S Membrane
NKPELAJD_03801 4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NKPELAJD_03802 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NKPELAJD_03803 7.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NKPELAJD_03804 1.8e-215 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKPELAJD_03805 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NKPELAJD_03806 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NKPELAJD_03807 6.1e-146 rsbR T Positive regulator of sigma-B
NKPELAJD_03808 1.8e-57 rsbS T antagonist
NKPELAJD_03809 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NKPELAJD_03810 4.6e-188 rsbU 3.1.3.3 KT phosphatase
NKPELAJD_03811 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NKPELAJD_03812 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NKPELAJD_03813 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKPELAJD_03814 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NKPELAJD_03815 0.0 yhgF K COG2183 Transcriptional accessory protein
NKPELAJD_03816 1.7e-14
NKPELAJD_03817 7.3e-58 ydcK S Belongs to the SprT family
NKPELAJD_03825 1.1e-08
NKPELAJD_03826 3.5e-29 S Doxx family
NKPELAJD_03827 3.3e-78 K Transcriptional regulator
NKPELAJD_03828 1.4e-97 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKPELAJD_03829 2.8e-96 ywrO 1.6.5.2 S Flavodoxin-like fold
NKPELAJD_03830 8.8e-230 proP EGP Transporter
NKPELAJD_03831 1.3e-48 ohrR K Transcriptional regulator
NKPELAJD_03832 3.9e-29 S Domain of unknown function with cystatin-like fold (DUF4467)
NKPELAJD_03833 3.9e-33 S Domain of unknown function with cystatin-like fold (DUF4467)
NKPELAJD_03834 5.1e-72 maoC I N-terminal half of MaoC dehydratase
NKPELAJD_03835 4.5e-63 yyaQ S YjbR
NKPELAJD_03836 3.1e-72 ywnA K Transcriptional regulator
NKPELAJD_03837 5.3e-113 ywnB S NAD(P)H-binding
NKPELAJD_03839 1.1e-88 K Bacterial regulatory proteins, tetR family
NKPELAJD_03840 2.6e-111 C Enoyl-(Acyl carrier protein) reductase
NKPELAJD_03841 2.5e-173 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NKPELAJD_03842 2e-191 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NKPELAJD_03843 1.4e-30 cspL K Cold shock
NKPELAJD_03844 1e-78 carD K Transcription factor
NKPELAJD_03845 5.8e-118 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NKPELAJD_03846 3.7e-102 S Protein of unknown function (DUF2812)
NKPELAJD_03847 1.3e-51 K Transcriptional regulator PadR-like family
NKPELAJD_03848 3.1e-181 S Patatin-like phospholipase
NKPELAJD_03849 1.7e-84 S DinB superfamily
NKPELAJD_03850 4.6e-61 G Cupin domain
NKPELAJD_03852 1.3e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
NKPELAJD_03853 8.9e-46 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKPELAJD_03854 6e-23 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKPELAJD_03855 9.3e-167 czcD P COG1230 Co Zn Cd efflux system component
NKPELAJD_03856 1.3e-201 trkA P Oxidoreductase
NKPELAJD_03858 2.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
NKPELAJD_03860 2.7e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NKPELAJD_03861 3.5e-56 ydeH
NKPELAJD_03862 1.4e-83 F nucleoside 2-deoxyribosyltransferase
NKPELAJD_03863 6.2e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKPELAJD_03864 3e-147 Q ubiE/COQ5 methyltransferase family
NKPELAJD_03865 4.2e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NKPELAJD_03866 3.4e-233 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NKPELAJD_03867 3.6e-28 S Sodium Bile acid symporter family
NKPELAJD_03868 6.9e-90 S Sodium Bile acid symporter family
NKPELAJD_03869 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
NKPELAJD_03870 3.6e-67 yraB K helix_turn_helix, mercury resistance
NKPELAJD_03871 5.6e-223 mleN_2 C antiporter
NKPELAJD_03872 2.7e-263 K helix_turn_helix gluconate operon transcriptional repressor
NKPELAJD_03873 3.5e-114 paiB K Transcriptional regulator
NKPELAJD_03875 3.8e-105 ksgA1 I Ribosomal RNA adenine dimethylase
NKPELAJD_03876 3.5e-123 T Transcriptional regulator
NKPELAJD_03877 6.4e-188 T PhoQ Sensor
NKPELAJD_03878 3.5e-101 S SNARE associated Golgi protein
NKPELAJD_03879 8.1e-176 ydeR EGP Major facilitator Superfamily
NKPELAJD_03880 1.3e-102 ydeS K Transcriptional regulator
NKPELAJD_03881 8.2e-157 ydeK EG -transporter
NKPELAJD_03882 2e-46 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKPELAJD_03883 4.7e-48 yraD M Spore coat protein
NKPELAJD_03884 3.1e-24 yraE
NKPELAJD_03885 7.4e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NKPELAJD_03886 1.4e-62 yraF M Spore coat protein
NKPELAJD_03887 3.8e-35 yraG
NKPELAJD_03888 2.5e-134 puuD S Peptidase C26
NKPELAJD_03889 2.3e-298 expZ S ABC transporter
NKPELAJD_03890 6.5e-101 ynaD J Acetyltransferase (GNAT) domain
NKPELAJD_03891 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
NKPELAJD_03892 3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
NKPELAJD_03893 2.3e-210 tcaB EGP Major facilitator Superfamily
NKPELAJD_03894 3.4e-225 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKPELAJD_03895 5e-156 K Helix-turn-helix XRE-family like proteins
NKPELAJD_03896 1.3e-123 ydhB S membrane transporter protein
NKPELAJD_03897 2.9e-81 bltD 2.3.1.57 K FR47-like protein
NKPELAJD_03898 4.1e-150 bltR K helix_turn_helix, mercury resistance
NKPELAJD_03899 5.3e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NKPELAJD_03900 2.7e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NKPELAJD_03901 4.4e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
NKPELAJD_03902 4e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NKPELAJD_03903 1.6e-120 ydhC K FCD
NKPELAJD_03904 3.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NKPELAJD_03907 4.3e-266 pbpE V Beta-lactamase
NKPELAJD_03909 1.2e-97 ydhK M Protein of unknown function (DUF1541)
NKPELAJD_03910 1.2e-195 pbuE EGP Major facilitator Superfamily
NKPELAJD_03911 5.1e-133 ydhQ K UTRA
NKPELAJD_03912 2.6e-118 K FCD
NKPELAJD_03913 1.7e-216 yeaN P COG2807 Cyanate permease
NKPELAJD_03914 2.6e-49 sugE P Small Multidrug Resistance protein
NKPELAJD_03915 2.3e-51 ykkC P Small Multidrug Resistance protein
NKPELAJD_03916 5.3e-104 yvdT K Transcriptional regulator
NKPELAJD_03917 3.5e-296 yveA E amino acid
NKPELAJD_03918 3.2e-166 ydhU P Catalase
NKPELAJD_03919 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NKPELAJD_03920 1.1e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
NKPELAJD_03921 1.2e-253 iolT EGP Major facilitator Superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)