ORF_ID e_value Gene_name EC_number CAZy COGs Description
HHBJICOG_00001 3.4e-107
HHBJICOG_00002 0.0 ydgH S MMPL family
HHBJICOG_00003 1.5e-98 yobS K Bacterial regulatory proteins, tetR family
HHBJICOG_00004 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
HHBJICOG_00005 1.8e-154 corA P CorA-like Mg2+ transporter protein
HHBJICOG_00006 2.5e-239 G Bacterial extracellular solute-binding protein
HHBJICOG_00007 2.4e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HHBJICOG_00008 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HHBJICOG_00009 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
HHBJICOG_00010 9.3e-203 malK P ATPases associated with a variety of cellular activities
HHBJICOG_00011 4e-19 pipD E Dipeptidase
HHBJICOG_00012 7e-236 pipD E Dipeptidase
HHBJICOG_00013 1.9e-158 endA F DNA RNA non-specific endonuclease
HHBJICOG_00014 1e-181 dnaQ 2.7.7.7 L EXOIII
HHBJICOG_00015 5.8e-157 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHBJICOG_00016 3e-116 yviA S Protein of unknown function (DUF421)
HHBJICOG_00017 1.1e-56 S Protein of unknown function (DUF3290)
HHBJICOG_00018 2.2e-89
HHBJICOG_00019 1.1e-08 isdH M Iron Transport-associated domain
HHBJICOG_00020 6.3e-123 M Iron Transport-associated domain
HHBJICOG_00021 8.7e-159 isdE P Periplasmic binding protein
HHBJICOG_00022 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHBJICOG_00023 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
HHBJICOG_00024 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHBJICOG_00025 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HHBJICOG_00026 1.3e-38 S RelB antitoxin
HHBJICOG_00027 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HHBJICOG_00028 0.0 S membrane
HHBJICOG_00029 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HHBJICOG_00030 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHBJICOG_00031 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHBJICOG_00032 4e-119 gluP 3.4.21.105 S Rhomboid family
HHBJICOG_00033 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HHBJICOG_00034 1.5e-65 yqhL P Rhodanese-like protein
HHBJICOG_00035 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHBJICOG_00036 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
HHBJICOG_00037 2e-263 glnA 6.3.1.2 E glutamine synthetase
HHBJICOG_00038 6.7e-170
HHBJICOG_00039 6e-148
HHBJICOG_00040 1.9e-21
HHBJICOG_00043 2.7e-34
HHBJICOG_00044 1.2e-128 S interspecies interaction between organisms
HHBJICOG_00046 9.1e-10 K peptidyl-tyrosine sulfation
HHBJICOG_00047 7.1e-263 E ABC transporter, substratebinding protein
HHBJICOG_00048 3.7e-66 K Helix-turn-helix domain, rpiR family
HHBJICOG_00049 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HHBJICOG_00050 8.4e-90 nanK GK ROK family
HHBJICOG_00051 3.1e-56 G Xylose isomerase domain protein TIM barrel
HHBJICOG_00052 2.1e-120 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HHBJICOG_00053 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHBJICOG_00054 1.3e-67 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HHBJICOG_00055 5.7e-24 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HHBJICOG_00056 7.7e-110 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HHBJICOG_00057 2.8e-125 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHBJICOG_00058 1.4e-107 yisY 1.11.1.10 S Alpha/beta hydrolase family
HHBJICOG_00059 3.5e-108 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HHBJICOG_00060 1.1e-75 2.7.1.191 G PTS system sorbose subfamily IIB component
HHBJICOG_00061 1e-48 2.7.1.191 G PTS system fructose IIA component
HHBJICOG_00062 3e-269 G PTS system mannose/fructose/sorbose family IID component
HHBJICOG_00063 2.3e-109 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HHBJICOG_00064 1.1e-114 K helix_turn _helix lactose operon repressor
HHBJICOG_00067 1.2e-128 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHBJICOG_00068 9.6e-130 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHBJICOG_00070 2.5e-137 cycA E Amino acid permease
HHBJICOG_00071 1.3e-27 L Initiator Replication protein
HHBJICOG_00072 2e-65 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
HHBJICOG_00077 9.7e-31 dnaG L DNA primase activity
HHBJICOG_00080 4.8e-86
HHBJICOG_00081 1.3e-223 U Psort location Cytoplasmic, score
HHBJICOG_00082 2.2e-87
HHBJICOG_00088 1e-43 L Probable transposase
HHBJICOG_00089 1.9e-101 L Probable transposase
HHBJICOG_00090 1.3e-227 potE E amino acid
HHBJICOG_00091 0.0 1.3.5.4 C FAD binding domain
HHBJICOG_00092 8.8e-58 S Peptidase propeptide and YPEB domain
HHBJICOG_00093 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHBJICOG_00094 7.4e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HHBJICOG_00095 7.9e-97 E GDSL-like Lipase/Acylhydrolase
HHBJICOG_00096 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
HHBJICOG_00097 1.6e-143 aatB ET ABC transporter substrate-binding protein
HHBJICOG_00098 1e-105 glnQ 3.6.3.21 E ABC transporter
HHBJICOG_00099 1.5e-107 glnP P ABC transporter permease
HHBJICOG_00100 0.0 helD 3.6.4.12 L DNA helicase
HHBJICOG_00101 2.3e-116 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HHBJICOG_00102 1.4e-126 pgm3 G Phosphoglycerate mutase family
HHBJICOG_00103 1.2e-241 S response to antibiotic
HHBJICOG_00104 3.2e-124
HHBJICOG_00105 0.0 3.6.3.8 P P-type ATPase
HHBJICOG_00106 4.3e-65 2.7.1.191 G PTS system fructose IIA component
HHBJICOG_00107 4.4e-43
HHBJICOG_00108 5.9e-09
HHBJICOG_00109 1.3e-30
HHBJICOG_00110 8e-69 T Toxin-antitoxin system, toxin component, MazF family
HHBJICOG_00111 2.2e-102 L Integrase
HHBJICOG_00112 8.2e-154 L Transposase
HHBJICOG_00113 4e-56 L Transposase
HHBJICOG_00114 6.5e-104 L PFAM Integrase catalytic
HHBJICOG_00115 1.6e-117 clcA P chloride
HHBJICOG_00116 1.6e-60 clcA P chloride
HHBJICOG_00117 4.7e-26 K FCD
HHBJICOG_00118 3.4e-15 K FCD
HHBJICOG_00119 1.5e-102 GM NmrA-like family
HHBJICOG_00120 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHBJICOG_00121 3.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHBJICOG_00122 2.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHBJICOG_00123 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHBJICOG_00124 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HHBJICOG_00125 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHBJICOG_00126 2.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHBJICOG_00127 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HHBJICOG_00128 3.5e-248 lctP C L-lactate permease
HHBJICOG_00129 4e-148 glcU U sugar transport
HHBJICOG_00130 3.5e-45
HHBJICOG_00131 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HHBJICOG_00132 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HHBJICOG_00133 1.1e-36 S Alpha beta hydrolase
HHBJICOG_00134 2.3e-65 S Alpha beta hydrolase
HHBJICOG_00135 1.9e-37
HHBJICOG_00136 4.9e-38
HHBJICOG_00137 4e-113 S haloacid dehalogenase-like hydrolase
HHBJICOG_00138 2e-291 V ABC-type multidrug transport system, ATPase and permease components
HHBJICOG_00139 4.1e-276 V ABC-type multidrug transport system, ATPase and permease components
HHBJICOG_00140 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HHBJICOG_00141 2.9e-178 I Carboxylesterase family
HHBJICOG_00143 1.7e-205 M Glycosyl hydrolases family 25
HHBJICOG_00144 1.3e-157 cinI S Serine hydrolase (FSH1)
HHBJICOG_00145 2.7e-300 S Predicted membrane protein (DUF2207)
HHBJICOG_00146 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HHBJICOG_00149 3.1e-87 gtcA S Teichoic acid glycosylation protein
HHBJICOG_00150 4.1e-80 fld C Flavodoxin
HHBJICOG_00151 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
HHBJICOG_00152 8e-163 yihY S Belongs to the UPF0761 family
HHBJICOG_00153 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHBJICOG_00154 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HHBJICOG_00155 5.9e-214 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HHBJICOG_00156 1.2e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HHBJICOG_00157 1e-44
HHBJICOG_00158 2.9e-27 D Alpha beta
HHBJICOG_00159 2.2e-119 D Alpha beta
HHBJICOG_00160 1.2e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHBJICOG_00161 3e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
HHBJICOG_00162 7.8e-85
HHBJICOG_00163 1.6e-74
HHBJICOG_00164 1.2e-141 hlyX S Transporter associated domain
HHBJICOG_00165 2.1e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHBJICOG_00166 8.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
HHBJICOG_00167 0.0 clpE O Belongs to the ClpA ClpB family
HHBJICOG_00168 8.5e-41 ptsH G phosphocarrier protein HPR
HHBJICOG_00169 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHBJICOG_00170 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHBJICOG_00171 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HHBJICOG_00172 3.3e-122 coiA 3.6.4.12 S Competence protein
HHBJICOG_00173 4e-13 coiA 3.6.4.12 S Competence protein
HHBJICOG_00174 4.6e-114 yjbH Q Thioredoxin
HHBJICOG_00175 5.2e-110 yjbK S CYTH
HHBJICOG_00176 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HHBJICOG_00177 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHBJICOG_00178 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHBJICOG_00179 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HHBJICOG_00180 4.2e-92 S SNARE associated Golgi protein
HHBJICOG_00181 8e-38
HHBJICOG_00182 3.7e-111 K WHG domain
HHBJICOG_00183 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HHBJICOG_00184 1e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
HHBJICOG_00185 6e-151 3.1.3.48 T Tyrosine phosphatase family
HHBJICOG_00186 2.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHBJICOG_00188 3e-53 cvpA S Colicin V production protein
HHBJICOG_00189 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HHBJICOG_00190 5e-148 noc K Belongs to the ParB family
HHBJICOG_00191 3.4e-138 soj D Sporulation initiation inhibitor
HHBJICOG_00192 1.5e-153 spo0J K Belongs to the ParB family
HHBJICOG_00193 2.8e-44 yyzM S Bacterial protein of unknown function (DUF951)
HHBJICOG_00194 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHBJICOG_00195 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
HHBJICOG_00196 1.2e-145 V ABC transporter, ATP-binding protein
HHBJICOG_00197 4.2e-144 V ABC transporter, ATP-binding protein
HHBJICOG_00198 0.0 V ABC transporter
HHBJICOG_00199 9.6e-121 K response regulator
HHBJICOG_00200 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HHBJICOG_00201 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHBJICOG_00202 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HHBJICOG_00203 1.4e-53 S Enterocin A Immunity
HHBJICOG_00204 2.5e-33
HHBJICOG_00205 9.5e-26
HHBJICOG_00206 1e-24
HHBJICOG_00207 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HHBJICOG_00208 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HHBJICOG_00209 2.1e-255 S Archaea bacterial proteins of unknown function
HHBJICOG_00210 1.2e-16
HHBJICOG_00211 4.4e-138 2.7.13.3 T GHKL domain
HHBJICOG_00212 1.2e-127 K LytTr DNA-binding domain
HHBJICOG_00213 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HHBJICOG_00214 1.4e-107 M Transport protein ComB
HHBJICOG_00215 2.2e-129 blpT
HHBJICOG_00219 3e-21
HHBJICOG_00220 3.7e-83
HHBJICOG_00221 8.2e-31 yozG K Transcriptional regulator
HHBJICOG_00222 2e-23
HHBJICOG_00223 1.7e-67
HHBJICOG_00224 1.1e-164 natA S ABC transporter, ATP-binding protein
HHBJICOG_00225 1.8e-218 natB CP ABC-2 family transporter protein
HHBJICOG_00226 1.8e-136 fruR K DeoR C terminal sensor domain
HHBJICOG_00227 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HHBJICOG_00228 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HHBJICOG_00229 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HHBJICOG_00230 1.4e-148 psaA P Belongs to the bacterial solute-binding protein 9 family
HHBJICOG_00231 1.6e-117 fhuC P ABC transporter
HHBJICOG_00232 5e-129 znuB U ABC 3 transport family
HHBJICOG_00233 2.5e-148 S Protein of unknown function (DUF805)
HHBJICOG_00234 3.4e-135 glnQ E ABC transporter, ATP-binding protein
HHBJICOG_00235 1.3e-290 glnP P ABC transporter permease
HHBJICOG_00236 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HHBJICOG_00237 5.8e-64 yeaO S Protein of unknown function, DUF488
HHBJICOG_00238 1.3e-124 terC P Integral membrane protein TerC family
HHBJICOG_00239 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HHBJICOG_00240 9.5e-112 L Resolvase, N-terminal
HHBJICOG_00241 2e-204 L Putative transposase DNA-binding domain
HHBJICOG_00242 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHBJICOG_00243 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHBJICOG_00244 1.7e-29 secG U Preprotein translocase
HHBJICOG_00245 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHBJICOG_00246 8.3e-177 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHBJICOG_00247 9.9e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
HHBJICOG_00248 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HHBJICOG_00255 2.2e-113 S SLAP domain
HHBJICOG_00256 2.6e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHBJICOG_00257 5.7e-46 S An automated process has identified a potential problem with this gene model
HHBJICOG_00258 1.5e-136 S Protein of unknown function (DUF3100)
HHBJICOG_00259 1.4e-245 3.5.1.47 S Peptidase dimerisation domain
HHBJICOG_00260 3.7e-148 Q Imidazolonepropionase and related amidohydrolases
HHBJICOG_00261 3.4e-73 Q Imidazolonepropionase and related amidohydrolases
HHBJICOG_00262 0.0 oppA E ABC transporter
HHBJICOG_00263 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
HHBJICOG_00264 0.0 mco Q Multicopper oxidase
HHBJICOG_00265 1.9e-25
HHBJICOG_00266 3.8e-136 metQ1 P Belongs to the nlpA lipoprotein family
HHBJICOG_00267 3.7e-168 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HHBJICOG_00268 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHBJICOG_00269 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHBJICOG_00270 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHBJICOG_00271 6.2e-157 cjaA ET ABC transporter substrate-binding protein
HHBJICOG_00272 3.3e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHBJICOG_00273 5.3e-116 P ABC transporter permease
HHBJICOG_00274 2.7e-107 papP P ABC transporter, permease protein
HHBJICOG_00276 4.5e-58 yodB K Transcriptional regulator, HxlR family
HHBJICOG_00277 7.7e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHBJICOG_00278 2.4e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HHBJICOG_00279 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHBJICOG_00280 1.3e-82 S Aminoacyl-tRNA editing domain
HHBJICOG_00281 6.1e-224 S SLAP domain
HHBJICOG_00282 9.2e-100 S CAAX protease self-immunity
HHBJICOG_00283 1e-12
HHBJICOG_00284 1.3e-277 arlS 2.7.13.3 T Histidine kinase
HHBJICOG_00285 1.2e-126 K response regulator
HHBJICOG_00286 1.1e-183 scrR K helix_turn _helix lactose operon repressor
HHBJICOG_00287 3.7e-295 scrB 3.2.1.26 GH32 G invertase
HHBJICOG_00288 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HHBJICOG_00289 2.3e-181 M CHAP domain
HHBJICOG_00290 1.3e-74
HHBJICOG_00291 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHBJICOG_00292 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHBJICOG_00293 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHBJICOG_00294 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHBJICOG_00295 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHBJICOG_00296 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHBJICOG_00297 9.6e-41 yajC U Preprotein translocase
HHBJICOG_00298 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHBJICOG_00299 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHBJICOG_00300 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HHBJICOG_00301 4.7e-228 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHBJICOG_00302 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHBJICOG_00303 2e-42 yrzL S Belongs to the UPF0297 family
HHBJICOG_00304 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHBJICOG_00305 1.1e-50 yrzB S Belongs to the UPF0473 family
HHBJICOG_00306 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHBJICOG_00307 3.5e-54 trxA O Belongs to the thioredoxin family
HHBJICOG_00308 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHBJICOG_00309 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHBJICOG_00310 0.0 typA T GTP-binding protein TypA
HHBJICOG_00311 2.7e-211 ftsW D Belongs to the SEDS family
HHBJICOG_00312 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HHBJICOG_00313 1.3e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HHBJICOG_00314 1.1e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHBJICOG_00315 6.9e-187 ylbL T Belongs to the peptidase S16 family
HHBJICOG_00316 3.1e-79 comEA L Competence protein ComEA
HHBJICOG_00317 0.0 comEC S Competence protein ComEC
HHBJICOG_00318 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
HHBJICOG_00319 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
HHBJICOG_00320 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHBJICOG_00321 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHBJICOG_00322 1.3e-148
HHBJICOG_00323 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHBJICOG_00324 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHBJICOG_00325 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHBJICOG_00326 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
HHBJICOG_00327 7.8e-39 yjeM E Amino Acid
HHBJICOG_00328 3.4e-175 yjeM E Amino Acid
HHBJICOG_00329 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHBJICOG_00330 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HHBJICOG_00331 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHBJICOG_00332 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHBJICOG_00333 5.2e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHBJICOG_00334 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHBJICOG_00335 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHBJICOG_00336 2.3e-215 aspC 2.6.1.1 E Aminotransferase
HHBJICOG_00337 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHBJICOG_00338 4.7e-194 pbpX1 V Beta-lactamase
HHBJICOG_00339 4.6e-299 I Protein of unknown function (DUF2974)
HHBJICOG_00340 1.8e-38 C FMN_bind
HHBJICOG_00341 3.9e-82
HHBJICOG_00342 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HHBJICOG_00343 6.4e-90 alkD L DNA alkylation repair enzyme
HHBJICOG_00344 6.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHBJICOG_00345 1.1e-127 K UTRA domain
HHBJICOG_00346 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HHBJICOG_00347 4.3e-59 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HHBJICOG_00348 3.2e-11
HHBJICOG_00349 3.7e-109 L Probable transposase
HHBJICOG_00350 1.1e-84 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHBJICOG_00351 2.5e-175 prmA J Ribosomal protein L11 methyltransferase
HHBJICOG_00352 4.2e-36
HHBJICOG_00353 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHBJICOG_00354 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHBJICOG_00355 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HHBJICOG_00356 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HHBJICOG_00357 9.8e-222 patA 2.6.1.1 E Aminotransferase
HHBJICOG_00359 1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHBJICOG_00360 4.8e-34 S reductase
HHBJICOG_00361 4.4e-39 S reductase
HHBJICOG_00362 2.7e-32 S reductase
HHBJICOG_00363 8.4e-148 yxeH S hydrolase
HHBJICOG_00364 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHBJICOG_00365 1.1e-243 yfnA E Amino Acid
HHBJICOG_00366 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
HHBJICOG_00367 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHBJICOG_00368 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHBJICOG_00369 7.7e-293 I Acyltransferase
HHBJICOG_00370 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHBJICOG_00371 1.9e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHBJICOG_00372 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
HHBJICOG_00373 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HHBJICOG_00374 1.8e-130 sip L Belongs to the 'phage' integrase family
HHBJICOG_00377 8.5e-24 S Hypothetical protein (DUF2513)
HHBJICOG_00378 7.4e-20 S Pfam:Peptidase_M78
HHBJICOG_00379 7.1e-19 ps115 K sequence-specific DNA binding
HHBJICOG_00382 1.4e-16
HHBJICOG_00383 3.6e-73 ps308 K AntA/AntB antirepressor
HHBJICOG_00384 9.5e-14
HHBJICOG_00390 5e-30 S HNH endonuclease
HHBJICOG_00391 6.1e-70 S AAA domain
HHBJICOG_00393 2.6e-154 res L Helicase C-terminal domain protein
HHBJICOG_00395 7.9e-41 S Protein of unknown function (DUF669)
HHBJICOG_00396 6.9e-272 S Phage plasmid primase, P4
HHBJICOG_00408 3.3e-37 S VRR_NUC
HHBJICOG_00410 7.7e-18
HHBJICOG_00411 2.5e-48 S HNH endonuclease
HHBJICOG_00412 4.2e-56 S Phage terminase, small subunit
HHBJICOG_00414 1.7e-212 S Phage Terminase
HHBJICOG_00416 2.2e-133 S Phage portal protein
HHBJICOG_00417 1.9e-87 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HHBJICOG_00418 1.6e-52 S peptidase activity
HHBJICOG_00419 5.5e-19 S Phage gp6-like head-tail connector protein
HHBJICOG_00421 2.8e-12 S Bacteriophage HK97-gp10, putative tail-component
HHBJICOG_00423 1.2e-12 S Pfam:Phage_TTP_1
HHBJICOG_00426 8.2e-129 M Phage tail tape measure protein TP901
HHBJICOG_00427 1.7e-33 S phage tail
HHBJICOG_00428 6e-136 S Phage minor structural protein
HHBJICOG_00437 4.5e-30 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HHBJICOG_00438 2.1e-85 S N-acetylmuramoyl-L-alanine amidase activity
HHBJICOG_00440 1.8e-10
HHBJICOG_00441 1.8e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HHBJICOG_00442 1.5e-22 S Protein of unknown function (DUF2929)
HHBJICOG_00443 0.0 dnaE 2.7.7.7 L DNA polymerase
HHBJICOG_00444 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHBJICOG_00445 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HHBJICOG_00446 1e-167 cvfB S S1 domain
HHBJICOG_00447 2.9e-165 xerD D recombinase XerD
HHBJICOG_00448 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHBJICOG_00449 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHBJICOG_00450 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHBJICOG_00451 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHBJICOG_00452 5.6e-36
HHBJICOG_00453 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHBJICOG_00454 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
HHBJICOG_00455 2.8e-135
HHBJICOG_00456 1.1e-257 glnPH2 P ABC transporter permease
HHBJICOG_00457 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHBJICOG_00458 6.4e-224 S Cysteine-rich secretory protein family
HHBJICOG_00459 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HHBJICOG_00460 1.4e-112
HHBJICOG_00461 2.2e-202 yibE S overlaps another CDS with the same product name
HHBJICOG_00462 4.9e-129 yibF S overlaps another CDS with the same product name
HHBJICOG_00463 2.7e-146 I alpha/beta hydrolase fold
HHBJICOG_00464 8.9e-133 L Phage integrase family
HHBJICOG_00465 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HHBJICOG_00466 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHBJICOG_00467 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHBJICOG_00468 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHBJICOG_00469 4.6e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHBJICOG_00470 4.1e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHBJICOG_00471 1.4e-60 rplQ J Ribosomal protein L17
HHBJICOG_00472 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHBJICOG_00473 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHBJICOG_00474 3.6e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHBJICOG_00475 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HHBJICOG_00476 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHBJICOG_00477 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHBJICOG_00478 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHBJICOG_00479 2.6e-71 rplO J Binds to the 23S rRNA
HHBJICOG_00480 2.3e-24 rpmD J Ribosomal protein L30
HHBJICOG_00481 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHBJICOG_00482 1.1e-54 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHBJICOG_00483 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHBJICOG_00484 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHBJICOG_00485 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHBJICOG_00486 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHBJICOG_00487 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHBJICOG_00488 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHBJICOG_00489 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHBJICOG_00490 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HHBJICOG_00491 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHBJICOG_00492 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHBJICOG_00493 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHBJICOG_00494 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHBJICOG_00495 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHBJICOG_00496 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHBJICOG_00497 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
HHBJICOG_00498 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHBJICOG_00499 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HHBJICOG_00500 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHBJICOG_00501 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHBJICOG_00502 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHBJICOG_00503 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HHBJICOG_00504 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHBJICOG_00505 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHBJICOG_00506 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHBJICOG_00507 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
HHBJICOG_00509 4.4e-192 L COG2963 Transposase and inactivated derivatives
HHBJICOG_00510 7e-83 S Phage portal protein
HHBJICOG_00511 1.4e-74 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HHBJICOG_00512 3.5e-50 S peptidase activity
HHBJICOG_00513 7.3e-17 S Phage gp6-like head-tail connector protein
HHBJICOG_00515 4.1e-23 S Bacteriophage HK97-gp10, putative tail-component
HHBJICOG_00516 8.1e-13 S Protein of unknown function (DUF806)
HHBJICOG_00517 1e-25 S Phage tail tube protein
HHBJICOG_00520 7e-158 M Phage tail tape measure protein TP901
HHBJICOG_00521 1.1e-37 S phage tail
HHBJICOG_00522 2.3e-49 S Phage minor structural protein
HHBJICOG_00523 9e-113 S Phage minor structural protein
HHBJICOG_00526 6.4e-55 E GDSL-like Lipase/Acylhydrolase
HHBJICOG_00530 2.2e-69 lysA2 M Glycosyl hydrolases family 25
HHBJICOG_00531 1e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHBJICOG_00532 2e-117 S Peptidase family M23
HHBJICOG_00533 6.2e-12
HHBJICOG_00534 1.2e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HHBJICOG_00535 2.3e-30
HHBJICOG_00537 2.9e-69 S Iron-sulphur cluster biosynthesis
HHBJICOG_00538 1.9e-112 yncA 2.3.1.79 S Maltose acetyltransferase
HHBJICOG_00539 6.2e-59 psiE S Phosphate-starvation-inducible E
HHBJICOG_00541 1.2e-42 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HHBJICOG_00542 2.9e-85 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HHBJICOG_00543 4.3e-228 amtB P ammonium transporter
HHBJICOG_00544 1.4e-60
HHBJICOG_00545 0.0 lhr L DEAD DEAH box helicase
HHBJICOG_00546 3.5e-244 P P-loop Domain of unknown function (DUF2791)
HHBJICOG_00547 0.0 S TerB-C domain
HHBJICOG_00548 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HHBJICOG_00549 6.7e-298 V ABC transporter transmembrane region
HHBJICOG_00550 2.3e-156 K Helix-turn-helix XRE-family like proteins
HHBJICOG_00551 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HHBJICOG_00552 2.1e-32
HHBJICOG_00553 1.4e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
HHBJICOG_00554 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
HHBJICOG_00555 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HHBJICOG_00556 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHBJICOG_00557 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HHBJICOG_00558 0.0 mtlR K Mga helix-turn-helix domain
HHBJICOG_00559 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHBJICOG_00560 6.8e-184 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHBJICOG_00561 8e-282 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHBJICOG_00562 1.7e-241 cycA E Amino acid permease
HHBJICOG_00563 1.3e-85 maa S transferase hexapeptide repeat
HHBJICOG_00564 3.3e-158 K Transcriptional regulator
HHBJICOG_00565 1.1e-62 manO S Domain of unknown function (DUF956)
HHBJICOG_00566 1e-173 manN G system, mannose fructose sorbose family IID component
HHBJICOG_00567 1.7e-129 manY G PTS system
HHBJICOG_00568 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HHBJICOG_00569 6.1e-151
HHBJICOG_00570 9.8e-239 steT E amino acid
HHBJICOG_00571 8.6e-243 steT E amino acid
HHBJICOG_00572 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HHBJICOG_00573 1.9e-147 glnH ET ABC transporter
HHBJICOG_00574 1.4e-80 K Transcriptional regulator, MarR family
HHBJICOG_00575 1.5e-308 XK27_09600 V ABC transporter, ATP-binding protein
HHBJICOG_00576 0.0 V ABC transporter transmembrane region
HHBJICOG_00577 8.4e-102 S ABC-type cobalt transport system, permease component
HHBJICOG_00578 4.7e-85 G MFS/sugar transport protein
HHBJICOG_00579 2.3e-151 G MFS/sugar transport protein
HHBJICOG_00580 4.7e-114 udk 2.7.1.48 F Zeta toxin
HHBJICOG_00581 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHBJICOG_00582 3.4e-149 glnH ET ABC transporter substrate-binding protein
HHBJICOG_00583 9.7e-91 gluC P ABC transporter permease
HHBJICOG_00584 6.8e-108 glnP P ABC transporter permease
HHBJICOG_00585 1.1e-164 S Protein of unknown function (DUF2974)
HHBJICOG_00586 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HHBJICOG_00587 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHBJICOG_00588 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHBJICOG_00589 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHBJICOG_00590 1.5e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHBJICOG_00591 1.8e-62 yabR J S1 RNA binding domain
HHBJICOG_00592 6.8e-60 divIC D Septum formation initiator
HHBJICOG_00593 1.6e-33 yabO J S4 domain protein
HHBJICOG_00594 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHBJICOG_00595 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHBJICOG_00596 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHBJICOG_00597 3.4e-129 S (CBS) domain
HHBJICOG_00598 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHBJICOG_00599 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHBJICOG_00600 4.8e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHBJICOG_00601 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHBJICOG_00602 2.5e-39 rpmE2 J Ribosomal protein L31
HHBJICOG_00603 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HHBJICOG_00604 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HHBJICOG_00605 9.5e-297 ybeC E amino acid
HHBJICOG_00606 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHBJICOG_00607 2.1e-42
HHBJICOG_00608 1.4e-51
HHBJICOG_00609 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
HHBJICOG_00610 1.3e-141 yfeO P Voltage gated chloride channel
HHBJICOG_00611 3.7e-174 L Bifunctional protein
HHBJICOG_00612 0.0 XK27_08315 M Sulfatase
HHBJICOG_00613 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHBJICOG_00614 5.2e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHBJICOG_00615 1.4e-98 G Aldose 1-epimerase
HHBJICOG_00616 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHBJICOG_00617 2.1e-116
HHBJICOG_00618 2.1e-130
HHBJICOG_00619 1.7e-160 S Oxidoreductase family, NAD-binding Rossmann fold
HHBJICOG_00620 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHBJICOG_00621 1.9e-113 yjbQ P TrkA C-terminal domain protein
HHBJICOG_00622 8.8e-177 yjbQ P TrkA C-terminal domain protein
HHBJICOG_00623 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HHBJICOG_00624 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHBJICOG_00628 8.5e-133 cobB K SIR2 family
HHBJICOG_00629 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
HHBJICOG_00630 2.4e-45 yitW S Iron-sulfur cluster assembly protein
HHBJICOG_00631 2e-266 sufB O assembly protein SufB
HHBJICOG_00632 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
HHBJICOG_00633 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHBJICOG_00634 3.5e-174 sufD O FeS assembly protein SufD
HHBJICOG_00635 2.8e-140 sufC O FeS assembly ATPase SufC
HHBJICOG_00636 5e-125 C 2Fe-2S iron-sulfur cluster binding domain
HHBJICOG_00637 2e-155 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
HHBJICOG_00638 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
HHBJICOG_00639 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HHBJICOG_00640 6.5e-169 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HHBJICOG_00641 2.8e-48 S Peptidase propeptide and YPEB domain
HHBJICOG_00642 6e-46 L An automated process has identified a potential problem with this gene model
HHBJICOG_00643 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HHBJICOG_00644 1.3e-113 tdk 2.7.1.21 F thymidine kinase
HHBJICOG_00645 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHBJICOG_00646 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHBJICOG_00647 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHBJICOG_00648 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHBJICOG_00649 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HHBJICOG_00650 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHBJICOG_00651 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHBJICOG_00652 6.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHBJICOG_00653 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHBJICOG_00654 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHBJICOG_00655 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHBJICOG_00656 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HHBJICOG_00657 2e-30 ywzB S Protein of unknown function (DUF1146)
HHBJICOG_00658 1.2e-177 mbl D Cell shape determining protein MreB Mrl
HHBJICOG_00659 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HHBJICOG_00660 3.3e-33 S Protein of unknown function (DUF2969)
HHBJICOG_00661 4.7e-216 rodA D Belongs to the SEDS family
HHBJICOG_00662 1.8e-78 usp6 T universal stress protein
HHBJICOG_00663 8.4e-39
HHBJICOG_00664 2.2e-238 rarA L recombination factor protein RarA
HHBJICOG_00665 1.3e-84 yueI S Protein of unknown function (DUF1694)
HHBJICOG_00666 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHBJICOG_00667 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHBJICOG_00668 5.1e-215 iscS2 2.8.1.7 E Aminotransferase class V
HHBJICOG_00669 8.8e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHBJICOG_00670 8.1e-123 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHBJICOG_00671 3.2e-77
HHBJICOG_00672 2.7e-285
HHBJICOG_00673 2.8e-08 S Fic/DOC family
HHBJICOG_00674 4.5e-49 S Fic/DOC family
HHBJICOG_00675 3.2e-278 yjeM E Amino Acid
HHBJICOG_00676 4.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHBJICOG_00677 5.4e-242 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HHBJICOG_00678 9.7e-136 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HHBJICOG_00679 1.2e-94 L Transposase
HHBJICOG_00680 5.3e-163 L Transposase
HHBJICOG_00681 3.3e-52 S Iron-sulfur cluster assembly protein
HHBJICOG_00682 8.5e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HHBJICOG_00683 3.4e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HHBJICOG_00684 1.5e-43
HHBJICOG_00685 2.7e-285 lsa S ABC transporter
HHBJICOG_00686 1.2e-10
HHBJICOG_00687 1.5e-63 K LytTr DNA-binding domain
HHBJICOG_00688 1.2e-49 S Protein of unknown function (DUF3021)
HHBJICOG_00689 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HHBJICOG_00690 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HHBJICOG_00691 6e-132 S membrane transporter protein
HHBJICOG_00692 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
HHBJICOG_00693 7.3e-161 czcD P cation diffusion facilitator family transporter
HHBJICOG_00694 1.4e-23
HHBJICOG_00695 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHBJICOG_00696 5.4e-183 S AAA domain
HHBJICOG_00697 6.3e-30
HHBJICOG_00698 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
HHBJICOG_00699 2.7e-51
HHBJICOG_00700 1.8e-230 steT_1 E amino acid
HHBJICOG_00701 2.2e-139 puuD S peptidase C26
HHBJICOG_00703 2.4e-172 V HNH endonuclease
HHBJICOG_00704 6.4e-135 S PFAM Archaeal ATPase
HHBJICOG_00705 9.2e-248 yifK E Amino acid permease
HHBJICOG_00706 9.7e-234 cycA E Amino acid permease
HHBJICOG_00707 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHBJICOG_00708 0.0 clpE O AAA domain (Cdc48 subfamily)
HHBJICOG_00709 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HHBJICOG_00710 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHBJICOG_00711 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
HHBJICOG_00712 0.0 XK27_06780 V ABC transporter permease
HHBJICOG_00713 1.9e-36
HHBJICOG_00714 7.9e-291 ytgP S Polysaccharide biosynthesis protein
HHBJICOG_00715 2.7e-137 lysA2 M Glycosyl hydrolases family 25
HHBJICOG_00716 2.3e-133 S Protein of unknown function (DUF975)
HHBJICOG_00717 2.9e-176 pbpX2 V Beta-lactamase
HHBJICOG_00718 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHBJICOG_00719 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHBJICOG_00720 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
HHBJICOG_00721 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHBJICOG_00722 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
HHBJICOG_00723 4.1e-44
HHBJICOG_00724 1e-207 ywhK S Membrane
HHBJICOG_00725 1.5e-80 ykuL S (CBS) domain
HHBJICOG_00726 0.0 cadA P P-type ATPase
HHBJICOG_00727 2.8e-205 napA P Sodium/hydrogen exchanger family
HHBJICOG_00728 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HHBJICOG_00729 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HHBJICOG_00730 4.1e-276 V ABC transporter transmembrane region
HHBJICOG_00731 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
HHBJICOG_00732 5.4e-51
HHBJICOG_00733 4.2e-154 EGP Major facilitator Superfamily
HHBJICOG_00734 1.6e-109 ropB K Transcriptional regulator
HHBJICOG_00735 9.1e-121 S CAAX protease self-immunity
HHBJICOG_00736 3.7e-191 S DUF218 domain
HHBJICOG_00737 0.0 macB_3 V ABC transporter, ATP-binding protein
HHBJICOG_00738 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HHBJICOG_00739 2.8e-100 S ECF transporter, substrate-specific component
HHBJICOG_00740 2.3e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
HHBJICOG_00741 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
HHBJICOG_00742 1.5e-283 xylG 3.6.3.17 S ABC transporter
HHBJICOG_00743 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
HHBJICOG_00744 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
HHBJICOG_00745 1.1e-68 yeaE S Aldo/keto reductase family
HHBJICOG_00746 1.8e-77 yeaE S Aldo/keto reductase family
HHBJICOG_00747 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHBJICOG_00748 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HHBJICOG_00749 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HHBJICOG_00750 2.7e-71
HHBJICOG_00751 7e-139 cof S haloacid dehalogenase-like hydrolase
HHBJICOG_00752 2.2e-230 pbuG S permease
HHBJICOG_00753 2.1e-76 S ABC-2 family transporter protein
HHBJICOG_00754 4.7e-60 S ABC-2 family transporter protein
HHBJICOG_00755 1.7e-93 V ABC transporter, ATP-binding protein
HHBJICOG_00756 2.7e-16 S Phage portal protein
HHBJICOG_00758 1.8e-217 S Phage Terminase
HHBJICOG_00761 9.3e-56 L Phage terminase, small subunit
HHBJICOG_00762 7.8e-62 L HNH nucleases
HHBJICOG_00763 1.1e-08
HHBJICOG_00769 1e-83 ps308 K AntA/AntB antirepressor
HHBJICOG_00774 1.1e-24 S HNH endonuclease
HHBJICOG_00775 1.3e-09
HHBJICOG_00778 1.1e-20 L Psort location Cytoplasmic, score
HHBJICOG_00786 2.3e-10 K Helix-turn-helix XRE-family like proteins
HHBJICOG_00787 6.2e-74 3.4.21.88 K Peptidase S24-like
HHBJICOG_00788 2.5e-30 S Hypothetical protein (DUF2513)
HHBJICOG_00791 1.6e-180 V Abi-like protein
HHBJICOG_00792 3.1e-122 L Belongs to the 'phage' integrase family
HHBJICOG_00793 2.3e-08 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHBJICOG_00795 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHBJICOG_00796 2.5e-118
HHBJICOG_00797 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHBJICOG_00798 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HHBJICOG_00799 1.3e-279 thrC 4.2.3.1 E Threonine synthase
HHBJICOG_00800 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HHBJICOG_00801 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HHBJICOG_00802 0.0 L PLD-like domain
HHBJICOG_00803 4.8e-42 S SnoaL-like domain
HHBJICOG_00804 5.4e-53 hipB K sequence-specific DNA binding
HHBJICOG_00805 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HHBJICOG_00806 3.4e-27
HHBJICOG_00807 1.6e-310 oppA E ABC transporter, substratebinding protein
HHBJICOG_00808 5e-301 oppA E ABC transporter, substratebinding protein
HHBJICOG_00809 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHBJICOG_00810 4.6e-257 pepC 3.4.22.40 E aminopeptidase
HHBJICOG_00812 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHBJICOG_00813 8.4e-265 S Fibronectin type III domain
HHBJICOG_00814 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHBJICOG_00815 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HHBJICOG_00816 1.5e-102 srtA 3.4.22.70 M sortase family
HHBJICOG_00817 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HHBJICOG_00818 5.9e-24
HHBJICOG_00819 6.7e-172 M Glycosyl hydrolases family 25
HHBJICOG_00820 5e-29
HHBJICOG_00821 7.9e-19
HHBJICOG_00823 1.1e-07
HHBJICOG_00824 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
HHBJICOG_00825 4.2e-38
HHBJICOG_00829 1.9e-36
HHBJICOG_00830 2.9e-09
HHBJICOG_00831 8.5e-125 Z012_12235 S Baseplate J-like protein
HHBJICOG_00832 4.3e-33
HHBJICOG_00833 1.2e-48
HHBJICOG_00834 1.1e-104
HHBJICOG_00835 2.1e-46
HHBJICOG_00836 6.7e-54 M LysM domain
HHBJICOG_00837 0.0 3.4.14.13 M Phage tail tape measure protein TP901
HHBJICOG_00839 6.9e-27
HHBJICOG_00840 4e-56
HHBJICOG_00841 5.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
HHBJICOG_00842 1.2e-55
HHBJICOG_00843 1.5e-44
HHBJICOG_00844 6.8e-76
HHBJICOG_00845 3.2e-31 S Protein of unknown function (DUF4054)
HHBJICOG_00846 7.1e-143 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HHBJICOG_00847 8.2e-60
HHBJICOG_00848 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
HHBJICOG_00849 1.1e-07 S Lysin motif
HHBJICOG_00850 2e-98 S Phage Mu protein F like protein
HHBJICOG_00851 6.3e-143 S Protein of unknown function (DUF1073)
HHBJICOG_00852 9.8e-232 S Terminase-like family
HHBJICOG_00853 2.7e-25 L Terminase small subunit
HHBJICOG_00854 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
HHBJICOG_00855 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
HHBJICOG_00862 2.1e-14
HHBJICOG_00863 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
HHBJICOG_00869 1.4e-51 dnaC L IstB-like ATP binding protein
HHBJICOG_00870 6.8e-33 S Conserved phage C-terminus (Phg_2220_C)
HHBJICOG_00871 6.9e-59 S Protein of unknown function (DUF1071)
HHBJICOG_00876 3.6e-09
HHBJICOG_00881 8e-97 S AntA/AntB antirepressor
HHBJICOG_00882 2.9e-12
HHBJICOG_00887 2.1e-76 S Phage antirepressor protein KilAC domain
HHBJICOG_00888 1.8e-10
HHBJICOG_00889 1.1e-12
HHBJICOG_00890 3.5e-15 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
HHBJICOG_00891 1.6e-10 E Zn peptidase
HHBJICOG_00892 6e-14
HHBJICOG_00896 1.6e-20 S YjcQ protein
HHBJICOG_00897 4.2e-180 sip L Belongs to the 'phage' integrase family
HHBJICOG_00898 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHBJICOG_00899 5.8e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHBJICOG_00900 0.0 dnaK O Heat shock 70 kDa protein
HHBJICOG_00901 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHBJICOG_00902 1.5e-61 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHBJICOG_00903 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HHBJICOG_00904 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHBJICOG_00905 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHBJICOG_00906 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHBJICOG_00907 3.2e-47 rplGA J ribosomal protein
HHBJICOG_00908 8.8e-47 ylxR K Protein of unknown function (DUF448)
HHBJICOG_00909 1.4e-196 nusA K Participates in both transcription termination and antitermination
HHBJICOG_00910 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HHBJICOG_00911 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHBJICOG_00912 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHBJICOG_00913 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HHBJICOG_00914 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
HHBJICOG_00915 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHBJICOG_00916 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHBJICOG_00917 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HHBJICOG_00918 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHBJICOG_00919 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HHBJICOG_00920 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
HHBJICOG_00921 3.2e-115 plsC 2.3.1.51 I Acyltransferase
HHBJICOG_00922 4e-220 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HHBJICOG_00923 0.0 pepO 3.4.24.71 O Peptidase family M13
HHBJICOG_00924 0.0 mdlB V ABC transporter
HHBJICOG_00925 0.0 mdlA V ABC transporter
HHBJICOG_00926 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
HHBJICOG_00927 3e-38 ynzC S UPF0291 protein
HHBJICOG_00928 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHBJICOG_00929 1.4e-20 E GDSL-like Lipase/Acylhydrolase family
HHBJICOG_00930 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HHBJICOG_00931 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HHBJICOG_00932 2.6e-214 yubA S AI-2E family transporter
HHBJICOG_00933 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHBJICOG_00934 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
HHBJICOG_00935 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HHBJICOG_00936 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HHBJICOG_00937 1.9e-236 S Peptidase M16
HHBJICOG_00938 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HHBJICOG_00939 2.1e-95 ymfM S Helix-turn-helix domain
HHBJICOG_00940 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHBJICOG_00941 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHBJICOG_00942 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
HHBJICOG_00943 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
HHBJICOG_00944 5.1e-119 yvyE 3.4.13.9 S YigZ family
HHBJICOG_00945 4.7e-246 comFA L Helicase C-terminal domain protein
HHBJICOG_00946 9.4e-132 comFC S Competence protein
HHBJICOG_00947 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHBJICOG_00948 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHBJICOG_00949 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHBJICOG_00950 5.1e-17
HHBJICOG_00951 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHBJICOG_00952 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHBJICOG_00953 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HHBJICOG_00954 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHBJICOG_00955 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HHBJICOG_00956 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHBJICOG_00957 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHBJICOG_00958 4.1e-90 S Short repeat of unknown function (DUF308)
HHBJICOG_00959 6.2e-165 rapZ S Displays ATPase and GTPase activities
HHBJICOG_00960 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HHBJICOG_00961 2.1e-171 whiA K May be required for sporulation
HHBJICOG_00962 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHBJICOG_00964 8.7e-19 spaC2 V Lanthionine synthetase C-like protein
HHBJICOG_00965 3.4e-99
HHBJICOG_00966 1.4e-133
HHBJICOG_00967 3.1e-100 V ATPases associated with a variety of cellular activities
HHBJICOG_00968 1.3e-146 ykuT M mechanosensitive ion channel
HHBJICOG_00969 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHBJICOG_00970 1.3e-36
HHBJICOG_00971 3.8e-273 pipD E Dipeptidase
HHBJICOG_00972 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HHBJICOG_00973 9.5e-176 hrtB V ABC transporter permease
HHBJICOG_00974 1.4e-90 ygfC K Bacterial regulatory proteins, tetR family
HHBJICOG_00975 3.5e-111 G phosphoglycerate mutase
HHBJICOG_00976 5.3e-84 S Protein of unknown function (DUF805)
HHBJICOG_00977 5.6e-68 O OsmC-like protein
HHBJICOG_00978 6.7e-207 EGP Major facilitator Superfamily
HHBJICOG_00979 2.5e-215 sptS 2.7.13.3 T Histidine kinase
HHBJICOG_00980 1.3e-65 K response regulator
HHBJICOG_00981 6e-27 K response regulator
HHBJICOG_00982 7.5e-109 2.7.6.5 T Region found in RelA / SpoT proteins
HHBJICOG_00983 6.2e-271 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HHBJICOG_00984 0.0 rafA 3.2.1.22 G alpha-galactosidase
HHBJICOG_00985 2.8e-210 msmX P Belongs to the ABC transporter superfamily
HHBJICOG_00986 2e-152 msmG P Binding-protein-dependent transport system inner membrane component
HHBJICOG_00987 4.8e-157 msmF P Binding-protein-dependent transport system inner membrane component
HHBJICOG_00988 2.3e-237 msmE G Bacterial extracellular solute-binding protein
HHBJICOG_00989 1.6e-158 scrR K Periplasmic binding protein domain
HHBJICOG_00990 5.5e-36
HHBJICOG_00991 2.2e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HHBJICOG_00992 2.9e-97 L An automated process has identified a potential problem with this gene model
HHBJICOG_00993 3.3e-127 L PFAM transposase IS116 IS110 IS902
HHBJICOG_00994 6.1e-111 crt 4.2.1.17 I Enoyl-CoA hydratase/isomerase
HHBJICOG_00995 9.3e-151 fabK 1.3.1.9 S Nitronate monooxygenase
HHBJICOG_00996 1.6e-82 2.8.3.1 I Coenzyme A transferase
HHBJICOG_00997 1.1e-149 2.8.3.1 I Coenzyme A transferase
HHBJICOG_00998 3.7e-144 gltC_1 3.1.3.48 K LysR substrate binding domain
HHBJICOG_00999 1.5e-54 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHBJICOG_01000 3.2e-75 S ECF transporter, substrate-specific component
HHBJICOG_01002 9.3e-74 coaA 2.7.1.33 F Pantothenic acid kinase
HHBJICOG_01003 1.4e-31 O OsmC-like protein
HHBJICOG_01005 1.5e-36 oppA E ABC transporter substrate-binding protein
HHBJICOG_01006 1.5e-180 S Domain of unknown function (DUF389)
HHBJICOG_01007 1.8e-79
HHBJICOG_01008 5.1e-69 L Transposase IS200 like
HHBJICOG_01010 3.5e-32
HHBJICOG_01014 2.9e-47 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HHBJICOG_01016 6.1e-18 M LysM domain
HHBJICOG_01021 1.4e-127 S Peptidase family M23
HHBJICOG_01022 4.8e-81 mutT 3.6.1.55 F NUDIX domain
HHBJICOG_01023 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HHBJICOG_01024 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHBJICOG_01025 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHBJICOG_01026 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
HHBJICOG_01027 2.8e-123 skfE V ATPases associated with a variety of cellular activities
HHBJICOG_01028 4.5e-141
HHBJICOG_01029 5.1e-137
HHBJICOG_01030 6.7e-145
HHBJICOG_01031 1.4e-26
HHBJICOG_01032 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHBJICOG_01033 7.5e-143
HHBJICOG_01034 9.7e-169
HHBJICOG_01035 7e-264 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HHBJICOG_01036 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HHBJICOG_01037 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHBJICOG_01038 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HHBJICOG_01039 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HHBJICOG_01040 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HHBJICOG_01041 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HHBJICOG_01042 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HHBJICOG_01043 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HHBJICOG_01044 9.2e-89 ypmB S Protein conserved in bacteria
HHBJICOG_01045 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HHBJICOG_01046 1.3e-114 dnaD L DnaD domain protein
HHBJICOG_01047 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHBJICOG_01048 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HHBJICOG_01049 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHBJICOG_01050 1e-107 ypsA S Belongs to the UPF0398 family
HHBJICOG_01051 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHBJICOG_01052 1.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HHBJICOG_01053 1e-242 cpdA S Calcineurin-like phosphoesterase
HHBJICOG_01054 3.4e-79
HHBJICOG_01055 1.1e-68 sagB C Nitroreductase family
HHBJICOG_01056 5.1e-56
HHBJICOG_01057 1.8e-131 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
HHBJICOG_01059 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HHBJICOG_01062 1.6e-48 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHBJICOG_01063 6.3e-07 M Domain of unknown function (DUF5011)
HHBJICOG_01065 6.6e-186 S regulation of response to stimulus
HHBJICOG_01067 5.7e-258 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HHBJICOG_01069 3.2e-62 D VirC1 protein
HHBJICOG_01070 6.9e-34 M CHAP domain
HHBJICOG_01075 1e-21
HHBJICOG_01079 1.3e-29 sip M LysM domain protein
HHBJICOG_01083 1.4e-18 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHBJICOG_01087 1.1e-66
HHBJICOG_01088 2.6e-35 yaaA S S4 domain protein YaaA
HHBJICOG_01089 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHBJICOG_01090 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHBJICOG_01091 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHBJICOG_01092 1.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HHBJICOG_01093 7.2e-76 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHBJICOG_01094 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHBJICOG_01095 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HHBJICOG_01096 5.7e-69 rplI J Binds to the 23S rRNA
HHBJICOG_01097 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HHBJICOG_01098 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HHBJICOG_01099 5.2e-170 degV S DegV family
HHBJICOG_01100 2.5e-135 V ABC transporter transmembrane region
HHBJICOG_01101 6.7e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HHBJICOG_01103 1.4e-16
HHBJICOG_01104 1.6e-227 I Protein of unknown function (DUF2974)
HHBJICOG_01105 9.2e-119 yhiD S MgtC family
HHBJICOG_01107 3.9e-131 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01108 7.4e-74
HHBJICOG_01109 3.3e-87
HHBJICOG_01110 3.3e-141 D Ftsk spoiiie family protein
HHBJICOG_01111 5.1e-145 S Replication initiation factor
HHBJICOG_01112 3.9e-55
HHBJICOG_01113 2.3e-26
HHBJICOG_01114 9.5e-220 L Belongs to the 'phage' integrase family
HHBJICOG_01116 2.5e-62 yfiL V ABC transporter
HHBJICOG_01117 2.9e-46 V Transport permease protein
HHBJICOG_01119 3e-112 L PFAM transposase IS116 IS110 IS902
HHBJICOG_01121 1.7e-28 mloB K Putative ATP-dependent DNA helicase recG C-terminal
HHBJICOG_01122 3.5e-248 lctP C L-lactate permease
HHBJICOG_01123 1.7e-143 L Transposase DDE domain
HHBJICOG_01124 2.3e-20
HHBJICOG_01126 2.9e-55 yxeH S hydrolase
HHBJICOG_01127 8.7e-80 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HHBJICOG_01128 5.9e-55 K DeoR C terminal sensor domain
HHBJICOG_01129 1.4e-51 pts36A 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HHBJICOG_01130 7.9e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HHBJICOG_01131 1.8e-195 pts36C G iic component
HHBJICOG_01133 1.5e-109 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
HHBJICOG_01134 2.7e-08 S RelB antitoxin
HHBJICOG_01139 1.7e-201 L Transposase DDE domain
HHBJICOG_01140 1.5e-95 S UPF0397 protein
HHBJICOG_01141 0.0 ykoD P ABC transporter, ATP-binding protein
HHBJICOG_01142 1.2e-144 cbiQ P cobalt transport
HHBJICOG_01143 1.8e-22
HHBJICOG_01144 7.9e-71 yeaL S Protein of unknown function (DUF441)
HHBJICOG_01145 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HHBJICOG_01146 3.8e-165 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HHBJICOG_01147 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
HHBJICOG_01148 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HHBJICOG_01149 1.1e-152 ydjP I Alpha/beta hydrolase family
HHBJICOG_01150 4.7e-274 P Sodium:sulfate symporter transmembrane region
HHBJICOG_01151 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
HHBJICOG_01152 4.1e-253 pepC 3.4.22.40 E Peptidase C1-like family
HHBJICOG_01153 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHBJICOG_01154 1.9e-261 frdC 1.3.5.4 C FAD binding domain
HHBJICOG_01155 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHBJICOG_01156 2e-73 metI P ABC transporter permease
HHBJICOG_01157 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHBJICOG_01158 1e-159 metQ2 P Belongs to the nlpA lipoprotein family
HHBJICOG_01159 5.8e-177 F DNA/RNA non-specific endonuclease
HHBJICOG_01160 0.0 aha1 P E1-E2 ATPase
HHBJICOG_01161 1.2e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHBJICOG_01162 3.1e-178 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHBJICOG_01163 2.4e-251 yifK E Amino acid permease
HHBJICOG_01164 7.6e-242 V ABC-type multidrug transport system, ATPase and permease components
HHBJICOG_01165 2.6e-286 P ABC transporter
HHBJICOG_01166 1.5e-36
HHBJICOG_01168 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HHBJICOG_01169 6.5e-87 K GNAT family
HHBJICOG_01170 7.8e-202 XK27_00915 C Luciferase-like monooxygenase
HHBJICOG_01171 2.3e-121 V Abi-like protein
HHBJICOG_01173 4e-137 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01174 2.3e-18
HHBJICOG_01175 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHBJICOG_01176 3.9e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHBJICOG_01177 7e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
HHBJICOG_01178 3.1e-178 yvdE K helix_turn _helix lactose operon repressor
HHBJICOG_01179 9.1e-204 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHBJICOG_01180 4.2e-56 S PAS domain
HHBJICOG_01181 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HHBJICOG_01182 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HHBJICOG_01183 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HHBJICOG_01184 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HHBJICOG_01185 3e-209 msmX P Belongs to the ABC transporter superfamily
HHBJICOG_01186 2.3e-213 malE G Bacterial extracellular solute-binding protein
HHBJICOG_01187 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
HHBJICOG_01188 3.3e-147 malG P ABC transporter permease
HHBJICOG_01189 1.5e-59 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01192 1.6e-28
HHBJICOG_01193 6.7e-09
HHBJICOG_01195 6.7e-88 ymdB S Macro domain protein
HHBJICOG_01196 4.3e-212 mdtG EGP Major facilitator Superfamily
HHBJICOG_01197 7.4e-175
HHBJICOG_01198 2.8e-47 lysM M LysM domain
HHBJICOG_01199 0.0 pepN 3.4.11.2 E aminopeptidase
HHBJICOG_01200 2.3e-82 yveB 2.7.4.29 I PAP2 superfamily
HHBJICOG_01201 3.2e-26 xerC L Phage integrase, N-terminal SAM-like domain
HHBJICOG_01202 3.2e-145 pstS P Phosphate
HHBJICOG_01203 1.3e-154 pstC P probably responsible for the translocation of the substrate across the membrane
HHBJICOG_01204 4.6e-152 pstA P Phosphate transport system permease protein PstA
HHBJICOG_01205 1.5e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHBJICOG_01206 1.2e-104 phoU P Plays a role in the regulation of phosphate uptake
HHBJICOG_01207 8.9e-119 T Transcriptional regulatory protein, C terminal
HHBJICOG_01208 2.5e-276 phoR 2.7.13.3 T Histidine kinase
HHBJICOG_01209 1.4e-192 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHBJICOG_01210 7.9e-73 nrdI F NrdI Flavodoxin like
HHBJICOG_01211 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHBJICOG_01212 3.7e-260 L Transposase
HHBJICOG_01213 4.2e-60
HHBJICOG_01221 3.5e-77 traI 5.99.1.2 L DNA topoisomerase
HHBJICOG_01222 3.7e-22 L Probable transposase
HHBJICOG_01228 1.7e-31 M NlpC/P60 family
HHBJICOG_01229 2.9e-09
HHBJICOG_01233 1.9e-256 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHBJICOG_01234 1.7e-118 U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHBJICOG_01237 1.1e-08 S CAAX amino terminal protease
HHBJICOG_01238 6.1e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHBJICOG_01239 5.4e-214 2.1.1.14 E methionine synthase, vitamin-B12 independent
HHBJICOG_01240 1.2e-11
HHBJICOG_01241 2e-25 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01245 8.4e-25 G Peptidase_C39 like family
HHBJICOG_01246 2.8e-162 M NlpC/P60 family
HHBJICOG_01247 6.5e-91 G Peptidase_C39 like family
HHBJICOG_01248 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HHBJICOG_01249 9.6e-78 P Cobalt transport protein
HHBJICOG_01250 1.4e-248 cbiO1 S ABC transporter, ATP-binding protein
HHBJICOG_01251 7.9e-174 K helix_turn_helix, arabinose operon control protein
HHBJICOG_01252 1.7e-157 htpX O Belongs to the peptidase M48B family
HHBJICOG_01253 9.7e-95 lemA S LemA family
HHBJICOG_01254 5.8e-192 ybiR P Citrate transporter
HHBJICOG_01255 2.9e-69 S Iron-sulphur cluster biosynthesis
HHBJICOG_01256 1.4e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HHBJICOG_01257 1.2e-17
HHBJICOG_01258 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
HHBJICOG_01259 1.5e-139 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HHBJICOG_01260 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHBJICOG_01261 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHBJICOG_01262 3.3e-11 GT2,GT4 M family 8
HHBJICOG_01263 1.1e-130 M Glycosyl hydrolases family 25
HHBJICOG_01264 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
HHBJICOG_01265 1.8e-248 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHBJICOG_01267 5.9e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HHBJICOG_01268 6.4e-243 cydA 1.10.3.14 C ubiquinol oxidase
HHBJICOG_01269 1.2e-172 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HHBJICOG_01270 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HHBJICOG_01271 4.1e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HHBJICOG_01272 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHBJICOG_01273 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHBJICOG_01274 3.6e-160 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HHBJICOG_01275 1.2e-230 ndh 1.6.99.3 C NADH dehydrogenase
HHBJICOG_01276 1.6e-43 1.3.5.4 C FAD binding domain
HHBJICOG_01277 1.6e-85 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHBJICOG_01278 2.6e-169 K LysR substrate binding domain
HHBJICOG_01279 6.4e-122 3.6.1.27 I Acid phosphatase homologues
HHBJICOG_01280 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHBJICOG_01281 6.8e-298 ytgP S Polysaccharide biosynthesis protein
HHBJICOG_01282 4.3e-47 pspC KT PspC domain
HHBJICOG_01284 1.6e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHBJICOG_01285 6.9e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHBJICOG_01286 7.9e-99 M ErfK YbiS YcfS YnhG
HHBJICOG_01287 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HHBJICOG_01288 6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HHBJICOG_01289 4.9e-34
HHBJICOG_01290 4.5e-68 S Domain of unknown function (DUF1934)
HHBJICOG_01291 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHBJICOG_01292 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHBJICOG_01293 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHBJICOG_01294 2.1e-80 K acetyltransferase
HHBJICOG_01295 1.3e-47 adk 2.7.4.3 F AAA domain
HHBJICOG_01296 2.2e-284 pipD E Dipeptidase
HHBJICOG_01297 2.5e-152 msmR K AraC-like ligand binding domain
HHBJICOG_01298 1.4e-226 pbuX F xanthine permease
HHBJICOG_01299 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHBJICOG_01300 2.4e-43 K Helix-turn-helix
HHBJICOG_01301 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HHBJICOG_01303 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHBJICOG_01304 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
HHBJICOG_01305 4.5e-185 3.2.1.18 GH33 M Rib/alpha-like repeat
HHBJICOG_01307 1.4e-34
HHBJICOG_01308 3.6e-63
HHBJICOG_01311 4.9e-118
HHBJICOG_01312 3.8e-104 pncA Q Isochorismatase family
HHBJICOG_01314 2e-35
HHBJICOG_01315 0.0 snf 2.7.11.1 KL domain protein
HHBJICOG_01316 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHBJICOG_01317 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHBJICOG_01318 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHBJICOG_01319 5.6e-183 K Transcriptional regulator
HHBJICOG_01320 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HHBJICOG_01321 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHBJICOG_01322 4e-57 K Helix-turn-helix domain
HHBJICOG_01323 2.7e-123 yoaK S Protein of unknown function (DUF1275)
HHBJICOG_01324 1.3e-125 S Uncharacterised protein family (UPF0236)
HHBJICOG_01325 6.1e-227 L COG3547 Transposase and inactivated derivatives
HHBJICOG_01326 0.0 V FtsX-like permease family
HHBJICOG_01327 4.1e-133 cysA V ABC transporter, ATP-binding protein
HHBJICOG_01328 3.4e-23
HHBJICOG_01330 2.5e-288 pipD E Dipeptidase
HHBJICOG_01331 7e-162 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHBJICOG_01332 0.0 smc D Required for chromosome condensation and partitioning
HHBJICOG_01333 5.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHBJICOG_01334 3e-307 oppA E ABC transporter substrate-binding protein
HHBJICOG_01335 2.4e-15 oppA E ABC transporter substrate-binding protein
HHBJICOG_01336 1.8e-116 oppA E ABC transporter substrate-binding protein
HHBJICOG_01337 7.4e-120 oppA E ABC transporter substrate-binding protein
HHBJICOG_01338 1.7e-128 oppC P Binding-protein-dependent transport system inner membrane component
HHBJICOG_01339 5.7e-172 oppB P ABC transporter permease
HHBJICOG_01340 1.9e-170 oppF P Belongs to the ABC transporter superfamily
HHBJICOG_01341 9.6e-194 oppD P Belongs to the ABC transporter superfamily
HHBJICOG_01342 9.8e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHBJICOG_01343 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHBJICOG_01344 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHBJICOG_01345 2e-305 yloV S DAK2 domain fusion protein YloV
HHBJICOG_01346 4e-57 asp S Asp23 family, cell envelope-related function
HHBJICOG_01347 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HHBJICOG_01348 1.1e-30
HHBJICOG_01349 2.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HHBJICOG_01350 1.7e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HHBJICOG_01351 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHBJICOG_01352 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HHBJICOG_01353 1.3e-139 stp 3.1.3.16 T phosphatase
HHBJICOG_01354 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHBJICOG_01355 1.6e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHBJICOG_01356 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHBJICOG_01357 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHBJICOG_01358 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HHBJICOG_01359 1.1e-77 6.3.3.2 S ASCH
HHBJICOG_01360 8.8e-293 recN L May be involved in recombinational repair of damaged DNA
HHBJICOG_01361 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HHBJICOG_01362 2.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHBJICOG_01363 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHBJICOG_01364 3.8e-185 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHBJICOG_01365 2.2e-143 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHBJICOG_01366 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHBJICOG_01367 1.7e-70 yqhY S Asp23 family, cell envelope-related function
HHBJICOG_01368 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHBJICOG_01369 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HHBJICOG_01370 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HHBJICOG_01371 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HHBJICOG_01372 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHBJICOG_01373 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
HHBJICOG_01374 7.4e-150 fhaB M Rib/alpha-like repeat
HHBJICOG_01375 6.8e-61 fhaB M Rib/alpha-like repeat
HHBJICOG_01376 7.7e-22
HHBJICOG_01377 9.3e-64 L PFAM IS66 Orf2 family protein
HHBJICOG_01378 8.7e-34 S Transposase C of IS166 homeodomain
HHBJICOG_01379 1.9e-245 L Transposase IS66 family
HHBJICOG_01381 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHBJICOG_01382 2.4e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHBJICOG_01383 3.7e-185
HHBJICOG_01384 6.1e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HHBJICOG_01385 1.5e-234 mepA V MATE efflux family protein
HHBJICOG_01386 8.4e-171 S SLAP domain
HHBJICOG_01387 7.4e-74 L Putative transposase DNA-binding domain
HHBJICOG_01388 1.7e-84 L Putative transposase DNA-binding domain
HHBJICOG_01389 1.4e-83 L Resolvase, N-terminal
HHBJICOG_01390 1.2e-157 M Peptidase family M1 domain
HHBJICOG_01391 2.7e-193 S Bacteriocin helveticin-J
HHBJICOG_01392 1.6e-18
HHBJICOG_01393 2.4e-50 L RelB antitoxin
HHBJICOG_01394 9.1e-140 qmcA O prohibitin homologues
HHBJICOG_01395 1.9e-199 purD 6.3.4.13 F Belongs to the GARS family
HHBJICOG_01396 1.3e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHBJICOG_01397 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHBJICOG_01398 5.7e-106 2.4.1.58 GT8 M family 8
HHBJICOG_01399 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HHBJICOG_01400 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHBJICOG_01401 2.4e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHBJICOG_01402 1.1e-34 S Protein of unknown function (DUF2508)
HHBJICOG_01403 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHBJICOG_01404 2.2e-51 yaaQ S Cyclic-di-AMP receptor
HHBJICOG_01405 3.7e-154 holB 2.7.7.7 L DNA polymerase III
HHBJICOG_01406 1.8e-59 yabA L Involved in initiation control of chromosome replication
HHBJICOG_01407 1.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHBJICOG_01408 8.4e-131 fat 3.1.2.21 I Acyl-ACP thioesterase
HHBJICOG_01409 2.2e-85 S ECF transporter, substrate-specific component
HHBJICOG_01410 8.2e-134 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HHBJICOG_01411 4.8e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HHBJICOG_01412 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHBJICOG_01413 1.3e-51 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHBJICOG_01414 3.2e-170 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHBJICOG_01415 5.3e-285 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HHBJICOG_01416 0.0 uup S ABC transporter, ATP-binding protein
HHBJICOG_01417 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHBJICOG_01418 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHBJICOG_01419 2.9e-221 ecsB U ABC transporter
HHBJICOG_01420 1.7e-134 ecsA V ABC transporter, ATP-binding protein
HHBJICOG_01421 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HHBJICOG_01422 3.9e-25
HHBJICOG_01423 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHBJICOG_01424 1.5e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HHBJICOG_01425 3.1e-265
HHBJICOG_01426 2.4e-51 S Domain of unknown function DUF1829
HHBJICOG_01427 2.9e-23
HHBJICOG_01428 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHBJICOG_01429 0.0 L AAA domain
HHBJICOG_01430 1.5e-230 yhaO L Ser Thr phosphatase family protein
HHBJICOG_01431 7.2e-56 yheA S Belongs to the UPF0342 family
HHBJICOG_01432 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHBJICOG_01433 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHBJICOG_01434 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HHBJICOG_01435 8.9e-10 G Phosphoglycerate mutase family
HHBJICOG_01436 2.9e-78 G Phosphoglycerate mutase family
HHBJICOG_01437 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HHBJICOG_01438 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HHBJICOG_01439 1.8e-193 I transferase activity, transferring acyl groups other than amino-acyl groups
HHBJICOG_01440 5.6e-179 S PFAM Archaeal ATPase
HHBJICOG_01441 6.8e-186 G Transmembrane secretion effector
HHBJICOG_01442 6.1e-136 V ABC transporter transmembrane region
HHBJICOG_01444 5.1e-33 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01445 1.4e-33 S Phage derived protein Gp49-like (DUF891)
HHBJICOG_01448 2.6e-146 S Putative ABC-transporter type IV
HHBJICOG_01449 1.7e-07 S LPXTG cell wall anchor motif
HHBJICOG_01450 1.6e-96 ybaT E Amino acid permease
HHBJICOG_01452 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01453 1.4e-22 S CAAX protease self-immunity
HHBJICOG_01454 1.5e-25 S CAAX protease self-immunity
HHBJICOG_01455 1.4e-83 K FR47-like protein
HHBJICOG_01456 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HHBJICOG_01457 5.1e-245 ynbB 4.4.1.1 P aluminum resistance
HHBJICOG_01458 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HHBJICOG_01459 3.2e-283 E Amino acid permease
HHBJICOG_01460 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HHBJICOG_01461 1.2e-271 pepV 3.5.1.18 E dipeptidase PepV
HHBJICOG_01462 1.4e-115 mmuP E amino acid
HHBJICOG_01463 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HHBJICOG_01464 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHBJICOG_01465 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHBJICOG_01466 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
HHBJICOG_01467 8e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HHBJICOG_01468 2.6e-115 dedA S SNARE-like domain protein
HHBJICOG_01469 3.7e-100 S Protein of unknown function (DUF1461)
HHBJICOG_01470 6.9e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHBJICOG_01471 1.7e-105 yutD S Protein of unknown function (DUF1027)
HHBJICOG_01472 9.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHBJICOG_01473 4.3e-55
HHBJICOG_01474 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHBJICOG_01475 3.2e-181 ccpA K catabolite control protein A
HHBJICOG_01476 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HHBJICOG_01479 4.2e-53 K LytTr DNA-binding domain
HHBJICOG_01480 7.7e-39 S Protein of unknown function (DUF3021)
HHBJICOG_01481 1.7e-168 V ABC transporter
HHBJICOG_01482 3.9e-23 S domain protein
HHBJICOG_01483 1.1e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HHBJICOG_01489 1.8e-110 U TraM recognition site of TraD and TraG
HHBJICOG_01491 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HHBJICOG_01492 2e-37 scrR K Periplasmic binding protein domain
HHBJICOG_01493 2.8e-33 scrR K Periplasmic binding protein domain
HHBJICOG_01494 3.2e-165 lacR K Transcriptional regulator
HHBJICOG_01495 0.0 lacS G Transporter
HHBJICOG_01496 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HHBJICOG_01497 2.1e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHBJICOG_01498 2.8e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HHBJICOG_01499 4.1e-172 L COG3385 FOG Transposase and inactivated derivatives
HHBJICOG_01500 0.0 G Belongs to the glycosyl hydrolase 31 family
HHBJICOG_01501 3e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHBJICOG_01502 5.4e-13
HHBJICOG_01503 5.2e-08
HHBJICOG_01504 3.6e-90 ntd 2.4.2.6 F Nucleoside
HHBJICOG_01505 1.7e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHBJICOG_01506 9.8e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HHBJICOG_01507 8.8e-84 uspA T universal stress protein
HHBJICOG_01509 1.2e-161 phnD P Phosphonate ABC transporter
HHBJICOG_01510 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HHBJICOG_01511 2.9e-121 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HHBJICOG_01512 8.4e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HHBJICOG_01513 5.9e-174 S Aldo keto reductase
HHBJICOG_01514 2.2e-311 ybiT S ABC transporter, ATP-binding protein
HHBJICOG_01515 1.7e-209 pepA E M42 glutamyl aminopeptidase
HHBJICOG_01516 1.9e-43
HHBJICOG_01517 6.9e-136
HHBJICOG_01518 1.1e-217 mdtG EGP Major facilitator Superfamily
HHBJICOG_01519 9.2e-262 emrY EGP Major facilitator Superfamily
HHBJICOG_01520 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHBJICOG_01521 2.9e-238 pyrP F Permease
HHBJICOG_01522 2.9e-287 K Putative DNA-binding domain
HHBJICOG_01523 2e-29
HHBJICOG_01524 7.8e-157 S reductase
HHBJICOG_01525 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
HHBJICOG_01526 1.2e-210 S Bacterial protein of unknown function (DUF871)
HHBJICOG_01528 2.3e-43 ybhL S Belongs to the BI1 family
HHBJICOG_01529 1.3e-74 M LysM domain
HHBJICOG_01530 4.5e-43
HHBJICOG_01534 3.4e-223 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHBJICOG_01535 8.1e-187 dltB M MBOAT, membrane-bound O-acyltransferase family
HHBJICOG_01536 1.8e-236 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHBJICOG_01538 8.5e-24 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHBJICOG_01539 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHBJICOG_01540 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHBJICOG_01541 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHBJICOG_01542 2.3e-198 oppD P Belongs to the ABC transporter superfamily
HHBJICOG_01543 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HHBJICOG_01544 5.2e-256 pepC 3.4.22.40 E aminopeptidase
HHBJICOG_01545 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
HHBJICOG_01546 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHBJICOG_01547 7.9e-112
HHBJICOG_01549 1.2e-111 E Belongs to the SOS response-associated peptidase family
HHBJICOG_01550 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHBJICOG_01551 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
HHBJICOG_01552 2e-103 S TPM domain
HHBJICOG_01553 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HHBJICOG_01554 1e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HHBJICOG_01555 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHBJICOG_01556 1e-147 tatD L hydrolase, TatD family
HHBJICOG_01557 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHBJICOG_01558 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHBJICOG_01559 4.5e-39 veg S Biofilm formation stimulator VEG
HHBJICOG_01560 1.1e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HHBJICOG_01561 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHBJICOG_01562 4.7e-19 M MucBP domain
HHBJICOG_01567 5.9e-17 D nuclear chromosome segregation
HHBJICOG_01568 3.7e-53 M Psort location Cellwall, score
HHBJICOG_01569 1.7e-102 ypuA S Protein of unknown function (DUF1002)
HHBJICOG_01570 4.7e-69 3.4.22.70 M sortase family
HHBJICOG_01577 9.9e-87
HHBJICOG_01578 7e-12 ispH 1.17.7.4 J negative regulation of cytoplasmic translation
HHBJICOG_01579 2.4e-21
HHBJICOG_01582 7.7e-50
HHBJICOG_01584 1.1e-139
HHBJICOG_01585 1.8e-31
HHBJICOG_01588 8.1e-37
HHBJICOG_01589 7.8e-56 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HHBJICOG_01590 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HHBJICOG_01591 0.0 copA 3.6.3.54 P P-type ATPase
HHBJICOG_01592 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HHBJICOG_01593 1.2e-105
HHBJICOG_01594 7e-248 EGP Sugar (and other) transporter
HHBJICOG_01595 1.2e-18
HHBJICOG_01596 2.8e-210
HHBJICOG_01597 3.5e-136 S SLAP domain
HHBJICOG_01598 1.3e-117 S SLAP domain
HHBJICOG_01599 1.1e-106 S Bacteriocin helveticin-J
HHBJICOG_01600 5.7e-44
HHBJICOG_01601 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01602 3.6e-33 E Zn peptidase
HHBJICOG_01603 2.1e-28 S Peptidase propeptide and YPEB domain
HHBJICOG_01604 2.4e-60 ypaA S Protein of unknown function (DUF1304)
HHBJICOG_01605 2.3e-309 oppA3 E ABC transporter, substratebinding protein
HHBJICOG_01606 3.5e-32 ykzG S Belongs to the UPF0356 family
HHBJICOG_01607 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHBJICOG_01608 1.2e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HHBJICOG_01609 1.6e-294 L Nuclease-related domain
HHBJICOG_01610 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHBJICOG_01611 8.3e-106 S Repeat protein
HHBJICOG_01612 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HHBJICOG_01613 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHBJICOG_01614 5.4e-56 XK27_04120 S Putative amino acid metabolism
HHBJICOG_01615 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
HHBJICOG_01616 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHBJICOG_01617 6.7e-37
HHBJICOG_01618 1.4e-101 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HHBJICOG_01619 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
HHBJICOG_01620 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHBJICOG_01621 2.8e-74 gpsB D DivIVA domain protein
HHBJICOG_01622 8.2e-148 ylmH S S4 domain protein
HHBJICOG_01623 1.7e-45 yggT S YGGT family
HHBJICOG_01624 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHBJICOG_01625 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHBJICOG_01626 6.7e-243 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHBJICOG_01627 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHBJICOG_01628 5.7e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHBJICOG_01629 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHBJICOG_01630 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHBJICOG_01631 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HHBJICOG_01632 1.8e-54 ftsL D Cell division protein FtsL
HHBJICOG_01633 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHBJICOG_01634 6.3e-78 mraZ K Belongs to the MraZ family
HHBJICOG_01635 6.4e-54 S Protein of unknown function (DUF3397)
HHBJICOG_01637 2.7e-94 mreD
HHBJICOG_01638 5.7e-147 mreC M Involved in formation and maintenance of cell shape
HHBJICOG_01639 2.4e-176 mreB D cell shape determining protein MreB
HHBJICOG_01640 2.3e-108 radC L DNA repair protein
HHBJICOG_01641 5.7e-126 S Haloacid dehalogenase-like hydrolase
HHBJICOG_01642 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHBJICOG_01643 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHBJICOG_01644 2.8e-35
HHBJICOG_01645 3.3e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
HHBJICOG_01646 0.0 3.6.3.8 P P-type ATPase
HHBJICOG_01648 2.9e-44
HHBJICOG_01649 1.5e-94 S Protein of unknown function (DUF3990)
HHBJICOG_01650 6.2e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HHBJICOG_01651 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
HHBJICOG_01652 4.7e-43 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHBJICOG_01653 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHBJICOG_01654 2.5e-155
HHBJICOG_01655 7.3e-46
HHBJICOG_01656 3.6e-39 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01657 1.3e-105 S Protein of unknown function (DUF3232)
HHBJICOG_01658 6e-61 L Transposase
HHBJICOG_01659 5.1e-69
HHBJICOG_01660 5e-200
HHBJICOG_01661 1.2e-94
HHBJICOG_01662 4.3e-152 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01663 4.1e-98 S SLAP domain
HHBJICOG_01664 1.8e-136 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01665 1.2e-79
HHBJICOG_01666 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HHBJICOG_01667 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHBJICOG_01668 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHBJICOG_01669 2.9e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHBJICOG_01670 6.7e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHBJICOG_01671 6.6e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHBJICOG_01672 4.2e-95 sigH K Belongs to the sigma-70 factor family
HHBJICOG_01673 1.7e-34
HHBJICOG_01674 1.9e-286 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HHBJICOG_01675 2.1e-70 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHBJICOG_01676 1.6e-246 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHBJICOG_01677 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHBJICOG_01678 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
HHBJICOG_01679 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHBJICOG_01680 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHBJICOG_01681 2.8e-157 pstS P Phosphate
HHBJICOG_01682 4.3e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HHBJICOG_01683 1e-154 pstA P Phosphate transport system permease protein PstA
HHBJICOG_01684 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHBJICOG_01685 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHBJICOG_01686 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
HHBJICOG_01687 9.7e-65 yagE E amino acid
HHBJICOG_01688 8.4e-128 yagE E Amino acid permease
HHBJICOG_01689 9.5e-86 3.4.21.96 S SLAP domain
HHBJICOG_01690 3.9e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHBJICOG_01691 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHBJICOG_01692 1.2e-107 hlyIII S protein, hemolysin III
HHBJICOG_01693 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
HHBJICOG_01694 7.1e-36 yozE S Belongs to the UPF0346 family
HHBJICOG_01695 1.1e-66 yjcE P NhaP-type Na H and K H
HHBJICOG_01696 1.5e-40 yjcE P Sodium proton antiporter
HHBJICOG_01697 1.9e-94 yjcE P Sodium proton antiporter
HHBJICOG_01698 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHBJICOG_01699 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHBJICOG_01700 5.8e-152 dprA LU DNA protecting protein DprA
HHBJICOG_01701 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHBJICOG_01702 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHBJICOG_01703 6.5e-141 xerC D Phage integrase, N-terminal SAM-like domain
HHBJICOG_01704 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HHBJICOG_01705 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HHBJICOG_01706 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
HHBJICOG_01707 1.1e-86 C Aldo keto reductase
HHBJICOG_01708 7.1e-63 M LysM domain protein
HHBJICOG_01709 1.4e-92 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT domain protein
HHBJICOG_01710 1.2e-280 ybgG 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HHBJICOG_01711 1.4e-150 mngA 2.7.1.195, 2.7.1.202 U system, fructose-specific IIC component
HHBJICOG_01712 5.3e-37 mngA 2.7.1.195, 2.7.1.202 G Psort location Cytoplasmic, score 9.98
HHBJICOG_01713 2e-42 fryA 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHBJICOG_01714 9e-161 V ABC transporter transmembrane region
HHBJICOG_01715 7e-68 V ABC transporter transmembrane region
HHBJICOG_01716 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
HHBJICOG_01717 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HHBJICOG_01718 2.5e-72 S Peptidase propeptide and YPEB domain
HHBJICOG_01719 5.8e-76 S Peptidase propeptide and YPEB domain
HHBJICOG_01720 5.2e-187 T GHKL domain
HHBJICOG_01721 3.1e-130 T Transcriptional regulatory protein, C terminal
HHBJICOG_01722 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HHBJICOG_01723 2.9e-277 V ABC transporter transmembrane region
HHBJICOG_01724 5.8e-100 L Helix-turn-helix domain
HHBJICOG_01725 3.8e-160 L hmm pf00665
HHBJICOG_01726 1.1e-75 V ABC transporter transmembrane region
HHBJICOG_01727 6.5e-64 L RelB antitoxin
HHBJICOG_01728 2.1e-131 cobQ S glutamine amidotransferase
HHBJICOG_01729 1.8e-81 M NlpC/P60 family
HHBJICOG_01732 2.6e-155
HHBJICOG_01733 7.8e-38
HHBJICOG_01734 2e-32
HHBJICOG_01735 6.2e-163 EG EamA-like transporter family
HHBJICOG_01736 5e-165 EG EamA-like transporter family
HHBJICOG_01737 1.2e-139 yicL EG EamA-like transporter family
HHBJICOG_01738 4.3e-107
HHBJICOG_01739 1.1e-110
HHBJICOG_01740 5.8e-186 XK27_05540 S DUF218 domain
HHBJICOG_01741 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
HHBJICOG_01742 7.2e-86
HHBJICOG_01743 3.9e-57
HHBJICOG_01744 4.7e-25 S Protein conserved in bacteria
HHBJICOG_01745 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
HHBJICOG_01746 3.5e-107 S Protein of unknown function (DUF1211)
HHBJICOG_01747 2.4e-273 lsa S ABC transporter
HHBJICOG_01748 2.8e-24 S Alpha beta hydrolase
HHBJICOG_01749 1.9e-237 brnQ U Component of the transport system for branched-chain amino acids
HHBJICOG_01750 2.5e-72 fcbD 2.7.8.12 GT2 M Glycosyltransferase like family 2
HHBJICOG_01751 2.4e-52 Z012_10770 M Domain of unknown function (DUF1919)
HHBJICOG_01752 2e-104 GT4 M Glycosyl transferases group 1
HHBJICOG_01753 1.3e-74 pssE S Glycosyltransferase family 28 C-terminal domain
HHBJICOG_01754 5e-49 cpsF M Oligosaccharide biosynthesis protein Alg14 like
HHBJICOG_01755 9.4e-158 M Glycosyltransferase
HHBJICOG_01756 9.1e-121 rfbP M Bacterial sugar transferase
HHBJICOG_01757 3.7e-145 ywqE 3.1.3.48 GM PHP domain protein
HHBJICOG_01758 5.8e-122 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HHBJICOG_01759 3.6e-144 epsB M biosynthesis protein
HHBJICOG_01760 1.7e-177 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHBJICOG_01761 2e-75 S cog cog0433
HHBJICOG_01762 1.9e-110 F DNA/RNA non-specific endonuclease
HHBJICOG_01763 2.7e-34 S YSIRK type signal peptide
HHBJICOG_01765 5.5e-53
HHBJICOG_01766 2.3e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HHBJICOG_01767 1.4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHBJICOG_01768 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHBJICOG_01769 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHBJICOG_01770 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HHBJICOG_01771 0.0 FbpA K Fibronectin-binding protein
HHBJICOG_01772 1.1e-66
HHBJICOG_01773 1.3e-159 degV S EDD domain protein, DegV family
HHBJICOG_01774 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHBJICOG_01775 5.4e-203 xerS L Belongs to the 'phage' integrase family
HHBJICOG_01776 4.1e-67
HHBJICOG_01777 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
HHBJICOG_01778 1.5e-211 M Glycosyl hydrolases family 25
HHBJICOG_01779 2e-39 S Transglycosylase associated protein
HHBJICOG_01780 5.8e-73 S domain protein
HHBJICOG_01782 4.9e-251 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HHBJICOG_01783 3e-145 potD2 P ABC transporter
HHBJICOG_01784 1.6e-135 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHBJICOG_01785 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component
HHBJICOG_01788 2.5e-15
HHBJICOG_01789 2.4e-85 endA F DNA RNA non-specific endonuclease
HHBJICOG_01790 1.3e-20 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHBJICOG_01791 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HHBJICOG_01792 8.9e-101 treR K UTRA
HHBJICOG_01793 7.3e-283 treB G phosphotransferase system
HHBJICOG_01794 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHBJICOG_01795 1.2e-190 yrvN L AAA C-terminal domain
HHBJICOG_01796 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHBJICOG_01797 9e-83 K Acetyltransferase (GNAT) domain
HHBJICOG_01798 1.3e-229 S Putative peptidoglycan binding domain
HHBJICOG_01799 7.5e-95 S ECF-type riboflavin transporter, S component
HHBJICOG_01800 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HHBJICOG_01801 9.3e-204 pbpX1 V Beta-lactamase
HHBJICOG_01802 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
HHBJICOG_01803 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHBJICOG_01804 7.4e-120 3.6.1.55 F NUDIX domain
HHBJICOG_01805 1.2e-117 L COG2826 Transposase and inactivated derivatives, IS30 family
HHBJICOG_01806 4.5e-189 ydaM M Glycosyl transferase
HHBJICOG_01807 5.6e-36 G Glycosyl hydrolases family 8
HHBJICOG_01808 3.1e-131 G Glycosyl hydrolases family 8
HHBJICOG_01809 1.1e-118 yfbR S HD containing hydrolase-like enzyme
HHBJICOG_01810 7.6e-160 L HNH nucleases
HHBJICOG_01811 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHBJICOG_01812 2.7e-18 M Lysin motif
HHBJICOG_01813 5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HHBJICOG_01814 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
HHBJICOG_01815 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HHBJICOG_01816 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHBJICOG_01817 8.7e-229 S Tetratricopeptide repeat protein
HHBJICOG_01818 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHBJICOG_01819 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HHBJICOG_01820 1.8e-122 gntR1 K UTRA
HHBJICOG_01821 2.5e-179
HHBJICOG_01822 1.9e-300 oppA2 E ABC transporter, substratebinding protein
HHBJICOG_01825 1.1e-240 npr 1.11.1.1 C NADH oxidase
HHBJICOG_01826 7.7e-12
HHBJICOG_01827 3.7e-22 3.6.4.12 S transposase or invertase
HHBJICOG_01828 6.7e-228 slpX S SLAP domain
HHBJICOG_01829 4.4e-144 K SIS domain
HHBJICOG_01830 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HHBJICOG_01831 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HHBJICOG_01832 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HHBJICOG_01834 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HHBJICOG_01836 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHBJICOG_01837 2.5e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HHBJICOG_01838 2.6e-89 G Histidine phosphatase superfamily (branch 1)
HHBJICOG_01839 1.2e-105 G Phosphoglycerate mutase family
HHBJICOG_01840 1.1e-158 D nuclear chromosome segregation
HHBJICOG_01841 5.8e-78 M LysM domain protein
HHBJICOG_01842 2.4e-93
HHBJICOG_01843 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HHBJICOG_01844 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
HHBJICOG_01845 1.5e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
HHBJICOG_01846 2.2e-101 K Helix-turn-helix domain, rpiR family
HHBJICOG_01847 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
HHBJICOG_01848 1.2e-225 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHBJICOG_01850 1.8e-104 3.2.2.20 K acetyltransferase
HHBJICOG_01851 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHBJICOG_01852 3e-24
HHBJICOG_01853 4.7e-13 rhaR K helix_turn_helix, arabinose operon control protein
HHBJICOG_01854 2.9e-72 S Bacterial transferase hexapeptide (six repeats)
HHBJICOG_01856 2.2e-59 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01857 1.7e-34 K Helix-turn-helix XRE-family like proteins
HHBJICOG_01860 8.8e-29
HHBJICOG_01861 3.8e-84 dps P Belongs to the Dps family
HHBJICOG_01862 1.8e-55 S pyridoxamine 5-phosphate
HHBJICOG_01863 2e-129 yobV1 K WYL domain
HHBJICOG_01864 1.9e-86 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HHBJICOG_01865 1.6e-78 dps P Belongs to the Dps family
HHBJICOG_01866 1.2e-30 copZ C Heavy-metal-associated domain
HHBJICOG_01867 1e-284 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HHBJICOG_01868 1.9e-30 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HHBJICOG_01869 6.3e-26 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HHBJICOG_01870 1.6e-172 MA20_14895 S Conserved hypothetical protein 698
HHBJICOG_01872 4.2e-178 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHBJICOG_01873 4.6e-100 3.6.1.27 I Acid phosphatase homologues
HHBJICOG_01874 2.2e-151 yitS S Uncharacterised protein, DegV family COG1307
HHBJICOG_01875 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHBJICOG_01876 7.5e-91 S Domain of unknown function (DUF4767)
HHBJICOG_01877 8e-38 C nitroreductase
HHBJICOG_01878 4.4e-36 C nitroreductase
HHBJICOG_01879 9.2e-137 ypbG 2.7.1.2 GK ROK family
HHBJICOG_01880 5.8e-274 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHBJICOG_01881 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHBJICOG_01882 4.2e-119 gmuR K UTRA
HHBJICOG_01883 5.4e-302 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHBJICOG_01884 3.2e-71 S Domain of unknown function (DUF3284)
HHBJICOG_01885 1.1e-248 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHBJICOG_01886 1.6e-61
HHBJICOG_01888 5.5e-30
HHBJICOG_01889 4.3e-40 S Protein of unknown function (DUF2922)
HHBJICOG_01890 4.1e-259 yfnA E amino acid
HHBJICOG_01891 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHBJICOG_01892 1.7e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHBJICOG_01893 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HHBJICOG_01894 1.7e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHBJICOG_01895 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HHBJICOG_01896 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHBJICOG_01897 6.7e-212 S SLAP domain
HHBJICOG_01898 2.1e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
HHBJICOG_01899 1.3e-114 E GDSL-like Lipase/Acylhydrolase family
HHBJICOG_01900 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHBJICOG_01901 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHBJICOG_01902 0.0 S SH3-like domain
HHBJICOG_01903 4.9e-111 ybbL S ABC transporter, ATP-binding protein
HHBJICOG_01904 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
HHBJICOG_01905 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHBJICOG_01906 6.6e-44
HHBJICOG_01907 1.6e-171 2.7.1.2 GK ROK family
HHBJICOG_01908 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHBJICOG_01909 2e-295 S SLAP domain
HHBJICOG_01910 5.3e-80
HHBJICOG_01911 1.2e-190 S Putative peptidoglycan binding domain
HHBJICOG_01912 4e-16
HHBJICOG_01913 7.9e-92 liaI S membrane
HHBJICOG_01914 1.7e-70 XK27_02470 K LytTr DNA-binding domain
HHBJICOG_01916 7.7e-10 C Flavodoxin
HHBJICOG_01917 3.2e-79 S X-Pro dipeptidyl-peptidase (S15 family)
HHBJICOG_01918 3.3e-45 K Tetracycline repressor, C-terminal all-alpha domain
HHBJICOG_01920 6.6e-90 K LysR substrate binding domain
HHBJICOG_01921 8.9e-34 S Domain of unknown function (DUF4440)
HHBJICOG_01922 1.3e-68 GM NAD(P)H-binding
HHBJICOG_01923 7e-135 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HHBJICOG_01924 1.2e-49 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHBJICOG_01925 5.3e-139 L hmm pf00665
HHBJICOG_01926 1.4e-98 L Helix-turn-helix domain
HHBJICOG_01927 2.2e-102
HHBJICOG_01930 5.7e-166 psaA P Belongs to the bacterial solute-binding protein 9 family
HHBJICOG_01933 8.7e-218 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHBJICOG_01934 2.4e-246 qacA EGP Major facilitator Superfamily
HHBJICOG_01935 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHBJICOG_01936 3.1e-151 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHBJICOG_01937 1.4e-183 yfeW 3.4.16.4 V Beta-lactamase
HHBJICOG_01938 3.1e-187 S Bacterial protein of unknown function (DUF871)
HHBJICOG_01939 4.5e-144 ybbH_2 K rpiR family
HHBJICOG_01940 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
HHBJICOG_01941 5.1e-181 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HHBJICOG_01942 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHBJICOG_01943 8.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHBJICOG_01944 4e-40 S CRISPR-associated protein (Cas_Csn2)
HHBJICOG_01945 6.5e-45
HHBJICOG_01947 8.2e-77 L Integrase
HHBJICOG_01951 6.2e-39 L Protein of unknown function (DUF3991)
HHBJICOG_01952 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HHBJICOG_01953 7e-146 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HHBJICOG_01954 4.5e-188 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHBJICOG_01955 6.4e-162 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HHBJICOG_01956 2e-106 K Transcriptional regulator, AbiEi antitoxin
HHBJICOG_01957 4.7e-188 K Periplasmic binding protein-like domain
HHBJICOG_01958 1.1e-78 2.7.13.3 T GHKL domain
HHBJICOG_01959 2.9e-79 K LytTr DNA-binding domain
HHBJICOG_01960 1.2e-304 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HHBJICOG_01961 3.9e-58
HHBJICOG_01962 2.5e-119 K helix_turn_helix, mercury resistance
HHBJICOG_01963 2.6e-86 pbuG S permease
HHBJICOG_01964 1.8e-128 pbuG S permease
HHBJICOG_01965 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
HHBJICOG_01966 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HHBJICOG_01967 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HHBJICOG_01968 1.3e-94 K Transcriptional regulator
HHBJICOG_01969 6.1e-61 K Transcriptional regulator
HHBJICOG_01970 2e-225 S cog cog1373
HHBJICOG_01971 9.7e-146 S haloacid dehalogenase-like hydrolase
HHBJICOG_01972 2.5e-226 pbuG S permease
HHBJICOG_01973 9.3e-86
HHBJICOG_01974 1.2e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHBJICOG_01975 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
HHBJICOG_01976 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHBJICOG_01977 4.4e-140 ypuA S Protein of unknown function (DUF1002)
HHBJICOG_01978 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
HHBJICOG_01979 7.3e-126 S Alpha/beta hydrolase family
HHBJICOG_01981 3.9e-33 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HHBJICOG_01982 3.2e-30 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HHBJICOG_01983 2.3e-35 UW LPXTG-motif cell wall anchor domain protein
HHBJICOG_01987 9.5e-259 emrY EGP Major facilitator Superfamily
HHBJICOG_01988 2.3e-90 yxdD K Bacterial regulatory proteins, tetR family
HHBJICOG_01989 1.2e-177 4.2.1.53 S Myosin-crossreactive antigen
HHBJICOG_01990 5e-164 4.2.1.53 S Myosin-crossreactive antigen
HHBJICOG_01991 2.2e-22
HHBJICOG_01992 3.3e-140 repB EP Plasmid replication protein
HHBJICOG_01993 2e-79 S helix_turn_helix, Deoxyribose operon repressor
HHBJICOG_01994 1e-48 S Metal binding domain of Ada
HHBJICOG_01995 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HHBJICOG_01996 1.2e-136 lysR5 K LysR substrate binding domain
HHBJICOG_01997 8.8e-234 arcA 3.5.3.6 E Arginine
HHBJICOG_01998 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHBJICOG_01999 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
HHBJICOG_02000 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HHBJICOG_02001 2.3e-215 S Sterol carrier protein domain
HHBJICOG_02002 1e-20
HHBJICOG_02003 4.9e-108 K LysR substrate binding domain
HHBJICOG_02004 9e-98
HHBJICOG_02005 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HHBJICOG_02006 1.4e-94
HHBJICOG_02007 5.4e-171 lmrB EGP Major facilitator Superfamily
HHBJICOG_02008 9.5e-34 rmaI K Transcriptional regulator
HHBJICOG_02009 1.6e-85
HHBJICOG_02013 3.9e-287 clcA P chloride
HHBJICOG_02014 3.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHBJICOG_02015 1.6e-31
HHBJICOG_02016 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HHBJICOG_02017 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHBJICOG_02018 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHBJICOG_02019 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHBJICOG_02020 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHBJICOG_02021 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HHBJICOG_02022 8e-150 S Metal-independent alpha-mannosidase (GH125)
HHBJICOG_02023 1.5e-06 2.7.11.1 UW LPXTG-motif cell wall anchor domain protein
HHBJICOG_02024 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
HHBJICOG_02026 1.6e-166 L Putative transposase DNA-binding domain
HHBJICOG_02027 5.4e-60 L Resolvase, N-terminal
HHBJICOG_02029 6.7e-66 xerS L Belongs to the 'phage' integrase family
HHBJICOG_02030 6.9e-249 dtpT U amino acid peptide transporter
HHBJICOG_02031 4.3e-75
HHBJICOG_02032 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHBJICOG_02033 1.3e-168 dnaI L Primosomal protein DnaI
HHBJICOG_02034 8.6e-251 dnaB L Replication initiation and membrane attachment
HHBJICOG_02035 3.9e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHBJICOG_02036 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHBJICOG_02037 9.4e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHBJICOG_02038 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHBJICOG_02039 3.8e-30
HHBJICOG_02040 5.7e-18
HHBJICOG_02041 1.5e-239 G Bacterial extracellular solute-binding protein
HHBJICOG_02042 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HHBJICOG_02043 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
HHBJICOG_02045 0.0 S SLAP domain
HHBJICOG_02046 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HHBJICOG_02047 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
HHBJICOG_02048 3.4e-42 S RloB-like protein
HHBJICOG_02049 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
HHBJICOG_02050 1.7e-98 3.1.21.3 V Type I restriction modification DNA specificity domain
HHBJICOG_02051 1.2e-63 S SIR2-like domain
HHBJICOG_02052 3.2e-10 S Domain of unknown function DUF87
HHBJICOG_02053 4e-36 S Cytochrome B5
HHBJICOG_02054 1.7e-167 arbZ I Phosphate acyltransferases
HHBJICOG_02055 8.7e-181 arbY M Glycosyl transferase family 8
HHBJICOG_02056 1.5e-143 arbY M Glycosyl transferase family 8
HHBJICOG_02057 1.4e-101 3.6.1.27 I Acid phosphatase homologues
HHBJICOG_02058 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HHBJICOG_02059 0.0 uvrA3 L excinuclease ABC, A subunit
HHBJICOG_02060 9.9e-82 C Flavodoxin
HHBJICOG_02061 0.0 1.3.5.4 C FAD binding domain
HHBJICOG_02062 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHBJICOG_02063 1.7e-249 yhdP S Transporter associated domain
HHBJICOG_02064 3.9e-119 C nitroreductase
HHBJICOG_02065 2.1e-39
HHBJICOG_02066 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HHBJICOG_02067 1.6e-80
HHBJICOG_02068 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
HHBJICOG_02069 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HHBJICOG_02070 5.4e-147 S hydrolase
HHBJICOG_02071 2e-160 rssA S Phospholipase, patatin family
HHBJICOG_02072 3.9e-107 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HHBJICOG_02073 3.1e-136 glcR K DeoR C terminal sensor domain
HHBJICOG_02074 2.5e-59 S Enterocin A Immunity
HHBJICOG_02075 1e-153 S hydrolase
HHBJICOG_02076 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
HHBJICOG_02077 9.1e-175 rihB 3.2.2.1 F Nucleoside
HHBJICOG_02078 0.0 kup P Transport of potassium into the cell
HHBJICOG_02079 3.4e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHBJICOG_02080 5.4e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHBJICOG_02081 1.3e-161 2.7.7.12 C Domain of unknown function (DUF4931)
HHBJICOG_02082 8.6e-221 G Bacterial extracellular solute-binding protein
HHBJICOG_02083 2e-210 S Uncharacterized protein conserved in bacteria (DUF2325)
HHBJICOG_02084 4e-98 rihB 3.2.2.1 F Nucleoside
HHBJICOG_02085 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHBJICOG_02086 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HHBJICOG_02087 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHBJICOG_02088 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HHBJICOG_02089 8.6e-199 tnpB L Putative transposase DNA-binding domain
HHBJICOG_02090 4.2e-84 yqeG S HAD phosphatase, family IIIA
HHBJICOG_02091 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
HHBJICOG_02092 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHBJICOG_02093 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HHBJICOG_02094 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHBJICOG_02095 4.6e-216 ylbM S Belongs to the UPF0348 family
HHBJICOG_02096 4.7e-97 yceD S Uncharacterized ACR, COG1399
HHBJICOG_02097 4e-08
HHBJICOG_02098 6.6e-56
HHBJICOG_02099 2.7e-57
HHBJICOG_02100 1.6e-11
HHBJICOG_02101 1.5e-124 S PAS domain
HHBJICOG_02102 1.4e-110 yjbF S SNARE associated Golgi protein
HHBJICOG_02103 1.7e-99 J Acetyltransferase (GNAT) domain
HHBJICOG_02104 1.8e-237 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHBJICOG_02105 1.1e-19 UW LPXTG-motif cell wall anchor domain protein
HHBJICOG_02106 9.6e-45 UW LPXTG-motif cell wall anchor domain protein
HHBJICOG_02107 9.3e-196 UW LPXTG-motif cell wall anchor domain protein
HHBJICOG_02108 7.1e-136 UW LPXTG-motif cell wall anchor domain protein
HHBJICOG_02109 1.4e-37 S Putative adhesin
HHBJICOG_02110 1.9e-144 V ABC transporter transmembrane region
HHBJICOG_02113 3.9e-195 ampC V Beta-lactamase
HHBJICOG_02114 2.4e-216 EGP Major facilitator Superfamily
HHBJICOG_02115 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HHBJICOG_02116 3.8e-105 vanZ V VanZ like family
HHBJICOG_02117 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHBJICOG_02118 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
HHBJICOG_02119 4.4e-129 K Transcriptional regulatory protein, C terminal
HHBJICOG_02120 7.7e-67 S SdpI/YhfL protein family
HHBJICOG_02121 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHBJICOG_02122 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
HHBJICOG_02123 1.3e-88 M Protein of unknown function (DUF3737)
HHBJICOG_02124 7.6e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HHBJICOG_02125 1e-12
HHBJICOG_02126 1.1e-71 yslB S Protein of unknown function (DUF2507)
HHBJICOG_02127 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HHBJICOG_02128 6.2e-111 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHBJICOG_02129 4.4e-40 ropB K Helix-turn-helix domain
HHBJICOG_02132 4.8e-131 K response regulator
HHBJICOG_02133 2.2e-305 vicK 2.7.13.3 T Histidine kinase
HHBJICOG_02134 2.1e-257 yycH S YycH protein
HHBJICOG_02135 3.4e-149 yycI S YycH protein
HHBJICOG_02136 4.1e-147 vicX 3.1.26.11 S domain protein
HHBJICOG_02137 1.6e-161 htrA 3.4.21.107 O serine protease
HHBJICOG_02138 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHBJICOG_02139 1.4e-150 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HHBJICOG_02140 9e-144 2.4.2.3 F Phosphorylase superfamily
HHBJICOG_02141 1.9e-138 2.4.2.3 F Phosphorylase superfamily
HHBJICOG_02142 3e-90 S PFAM Archaeal ATPase
HHBJICOG_02143 5.1e-91 S PFAM Archaeal ATPase
HHBJICOG_02144 7.7e-26
HHBJICOG_02145 4.3e-76 menA 2.5.1.74 H UbiA prenyltransferase family
HHBJICOG_02146 1e-95
HHBJICOG_02147 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
HHBJICOG_02148 1.2e-94
HHBJICOG_02149 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HHBJICOG_02150 8.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHBJICOG_02151 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HHBJICOG_02152 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HHBJICOG_02153 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
HHBJICOG_02154 2e-163 murB 1.3.1.98 M Cell wall formation
HHBJICOG_02155 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHBJICOG_02156 1.3e-129 potB P ABC transporter permease
HHBJICOG_02157 4.8e-127 potC P ABC transporter permease
HHBJICOG_02158 7.3e-208 potD P ABC transporter
HHBJICOG_02159 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHBJICOG_02160 2e-172 ybbR S YbbR-like protein
HHBJICOG_02161 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHBJICOG_02162 1.4e-147 S hydrolase
HHBJICOG_02163 1.8e-75 K Penicillinase repressor
HHBJICOG_02164 1.4e-117
HHBJICOG_02165 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHBJICOG_02166 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HHBJICOG_02167 8.3e-143 licT K CAT RNA binding domain
HHBJICOG_02168 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHBJICOG_02169 9.1e-302 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHBJICOG_02170 6.9e-178 D Alpha beta
HHBJICOG_02171 2.8e-304 E Amino acid permease
HHBJICOG_02173 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHBJICOG_02174 5.1e-108 ylbE GM NAD(P)H-binding
HHBJICOG_02175 2.9e-93 S VanZ like family
HHBJICOG_02176 8.9e-133 yebC K Transcriptional regulatory protein
HHBJICOG_02177 2e-155 comGA NU Type II IV secretion system protein
HHBJICOG_02178 1.7e-171 comGB NU type II secretion system
HHBJICOG_02179 3.1e-43 comGC U competence protein ComGC
HHBJICOG_02180 7.4e-71
HHBJICOG_02181 8.6e-41
HHBJICOG_02182 9.4e-76 comGF U Putative Competence protein ComGF
HHBJICOG_02183 1.6e-21
HHBJICOG_02184 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
HHBJICOG_02185 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHBJICOG_02187 1.8e-153 L Belongs to the 'phage' integrase family
HHBJICOG_02188 5e-08 S Pfam:DUF955
HHBJICOG_02189 1.2e-23 K Helix-turn-helix domain
HHBJICOG_02190 9e-22 XK27_07105 K Helix-turn-helix XRE-family like proteins
HHBJICOG_02191 2.6e-31 K Helix-turn-helix domain
HHBJICOG_02193 4.1e-09 S Arc-like DNA binding domain
HHBJICOG_02195 5.7e-21 K Conserved phage C-terminus (Phg_2220_C)
HHBJICOG_02196 1e-25 S Domain of unknown function (DUF771)
HHBJICOG_02203 2.6e-11 ssb L Single-strand binding protein family
HHBJICOG_02209 7e-24 srtA 3.4.22.70 M sortase family
HHBJICOG_02211 1.3e-39 M domain protein
HHBJICOG_02212 6.8e-15 S SLAP domain
HHBJICOG_02213 1.3e-30 M domain protein
HHBJICOG_02217 2.4e-141 U TraM recognition site of TraD and TraG
HHBJICOG_02218 2.3e-32 I mechanosensitive ion channel activity
HHBJICOG_02220 8.4e-15
HHBJICOG_02221 8.1e-160 trsE S COG0433 Predicted ATPase
HHBJICOG_02222 1.2e-32 M Peptidase family M23
HHBJICOG_02225 2.4e-18 CO COG0526, thiol-disulfide isomerase and thioredoxins
HHBJICOG_02231 3.4e-52 S COG0790 FOG TPR repeat, SEL1 subfamily
HHBJICOG_02232 1.7e-39 L Protein of unknown function (DUF3991)
HHBJICOG_02233 4.6e-111 S Fic/DOC family
HHBJICOG_02234 2.5e-47 L Psort location Cytoplasmic, score
HHBJICOG_02235 2.6e-24 relB L Addiction module antitoxin, RelB DinJ family
HHBJICOG_02236 8.1e-17 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HHBJICOG_02237 8.6e-82 yxaM EGP Major facilitator Superfamily
HHBJICOG_02238 5.2e-69 yxaM EGP Major facilitator Superfamily
HHBJICOG_02239 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
HHBJICOG_02240 1e-79 S AAA domain
HHBJICOG_02241 3.3e-61 3.6.1.55 F NUDIX domain
HHBJICOG_02242 2.2e-67 S cog cog1373
HHBJICOG_02243 6.2e-93 F Nucleoside 2-deoxyribosyltransferase
HHBJICOG_02244 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
HHBJICOG_02245 8.9e-276 V ABC-type multidrug transport system, ATPase and permease components
HHBJICOG_02246 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHBJICOG_02247 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HHBJICOG_02248 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHBJICOG_02249 3.3e-189 cggR K Putative sugar-binding domain
HHBJICOG_02251 2.8e-290
HHBJICOG_02252 4.6e-274 ycaM E amino acid
HHBJICOG_02253 3.1e-139 S Cysteine-rich secretory protein family
HHBJICOG_02254 4.2e-77 K MerR HTH family regulatory protein
HHBJICOG_02255 7e-262 lmrB EGP Major facilitator Superfamily
HHBJICOG_02256 3.1e-48 S Domain of unknown function (DUF4811)
HHBJICOG_02257 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
HHBJICOG_02258 0.0 L Plasmid pRiA4b ORF-3-like protein
HHBJICOG_02259 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
HHBJICOG_02260 9e-121
HHBJICOG_02261 2.2e-142 S Belongs to the UPF0246 family
HHBJICOG_02262 4.1e-141 aroD S Alpha/beta hydrolase family
HHBJICOG_02265 1.3e-149 oppA E ABC transporter substrate-binding protein
HHBJICOG_02266 2.2e-54 oppA E ABC transporter substrate-binding protein
HHBJICOG_02267 2.9e-66 S Domain of unknown function DUF1828
HHBJICOG_02268 5.5e-09
HHBJICOG_02269 3.8e-51
HHBJICOG_02270 2.6e-177 citR K Putative sugar-binding domain
HHBJICOG_02271 1.9e-250 yjjP S Putative threonine/serine exporter
HHBJICOG_02273 1.4e-39
HHBJICOG_02274 2.3e-25 M domain protein
HHBJICOG_02275 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
HHBJICOG_02276 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HHBJICOG_02279 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHBJICOG_02280 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHBJICOG_02281 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHBJICOG_02282 7.3e-21 hicA S HicA toxin of bacterial toxin-antitoxin,
HHBJICOG_02283 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
HHBJICOG_02284 1.5e-155 arbx M Glycosyl transferase family 8
HHBJICOG_02285 3.4e-164 msmX P Belongs to the ABC transporter superfamily
HHBJICOG_02286 5e-226 L Transposase
HHBJICOG_02287 1.8e-125 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHBJICOG_02288 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHBJICOG_02289 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
HHBJICOG_02290 2.9e-48 5.3.1.27 M SIS domain
HHBJICOG_02291 9.4e-64 kdsD 5.3.1.13 M SIS domain
HHBJICOG_02292 1.4e-76 S Uncharacterised protein family UPF0047
HHBJICOG_02293 7.6e-35 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HHBJICOG_02294 7.9e-201 G PTS system sugar-specific permease component
HHBJICOG_02295 1.5e-40 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHBJICOG_02296 9.9e-67 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HHBJICOG_02297 8.5e-151 S Membrane protein involved in the export of O-antigen and teichoic acid
HHBJICOG_02298 6.2e-36 epsJ_2 M Glycosyltransferase like family 2
HHBJICOG_02299 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HHBJICOG_02300 5.1e-226 N Uncharacterized conserved protein (DUF2075)
HHBJICOG_02301 4.8e-205 pbpX1 V Beta-lactamase
HHBJICOG_02302 0.0 L Helicase C-terminal domain protein
HHBJICOG_02303 1.3e-273 E amino acid
HHBJICOG_02304 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HHBJICOG_02307 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHBJICOG_02308 7.6e-134 EGP Major facilitator Superfamily
HHBJICOG_02309 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
HHBJICOG_02310 0.0 tetP J elongation factor G
HHBJICOG_02311 1.2e-160 yvgN C Aldo keto reductase
HHBJICOG_02312 2e-155 P CorA-like Mg2+ transporter protein
HHBJICOG_02313 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HHBJICOG_02314 1.7e-174 ABC-SBP S ABC transporter
HHBJICOG_02315 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HHBJICOG_02316 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
HHBJICOG_02317 5.2e-248 G Major Facilitator
HHBJICOG_02318 4.1e-18
HHBJICOG_02319 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HHBJICOG_02320 6.4e-177 K AI-2E family transporter
HHBJICOG_02321 2.7e-109 oppA E ABC transporter substrate-binding protein
HHBJICOG_02322 1.2e-210 oppA E ABC transporter substrate-binding protein
HHBJICOG_02323 5.2e-117 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HHBJICOG_02324 7.2e-29 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S regulation of response to stimulus
HHBJICOG_02325 1.6e-102 ltrA S Bacterial low temperature requirement A protein (LtrA)
HHBJICOG_02326 3.4e-121 infB M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HHBJICOG_02328 2.3e-101 L An automated process has identified a potential problem with this gene model
HHBJICOG_02329 4.6e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HHBJICOG_02330 4e-60 L Resolvase, N terminal domain
HHBJICOG_02331 4.8e-47
HHBJICOG_02332 5e-47 2.4.1.33 V HlyD family secretion protein
HHBJICOG_02336 3e-134 S CAAX amino terminal protease
HHBJICOG_02337 7.4e-40 S Enterocin A Immunity
HHBJICOG_02338 0.0 pepF E oligoendopeptidase F
HHBJICOG_02339 2.2e-208 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHBJICOG_02340 6.5e-125 S Protein of unknown function (DUF554)
HHBJICOG_02341 8.2e-61
HHBJICOG_02342 5.6e-19
HHBJICOG_02343 1.2e-97 rimL J Acetyltransferase (GNAT) domain
HHBJICOG_02344 8.3e-58
HHBJICOG_02345 8.9e-292 S ABC transporter
HHBJICOG_02346 2.4e-136 thrE S Putative threonine/serine exporter
HHBJICOG_02347 1.1e-83 S Threonine/Serine exporter, ThrE
HHBJICOG_02348 9.1e-112 yvpB S Peptidase_C39 like family
HHBJICOG_02349 2.5e-68
HHBJICOG_02350 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHBJICOG_02351 5.5e-77 nrdI F NrdI Flavodoxin like
HHBJICOG_02352 2.3e-223 tnpB L Putative transposase DNA-binding domain
HHBJICOG_02353 3.3e-112
HHBJICOG_02354 6.5e-279 S O-antigen ligase like membrane protein
HHBJICOG_02355 3.9e-42
HHBJICOG_02356 7.7e-89 gmk2 2.7.4.8 F Guanylate kinase homologues.
HHBJICOG_02357 2e-89 M NlpC/P60 family
HHBJICOG_02358 1.4e-136 M NlpC P60 family protein
HHBJICOG_02359 2.6e-118 M NlpC/P60 family
HHBJICOG_02360 3.5e-41
HHBJICOG_02361 3.5e-175 S Cysteine-rich secretory protein family
HHBJICOG_02362 1.5e-215 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHBJICOG_02364 1.7e-29 S Predicted membrane protein (DUF2335)
HHBJICOG_02366 4.1e-66 L PFAM transposase, IS4 family protein
HHBJICOG_02367 4.9e-35
HHBJICOG_02368 2.9e-73 yniG EGP Major facilitator Superfamily
HHBJICOG_02369 9.2e-237 L transposase, IS605 OrfB family
HHBJICOG_02370 4.7e-92 yniG EGP Major facilitator Superfamily
HHBJICOG_02371 7.1e-124 S SLAP domain
HHBJICOG_02373 5.3e-41
HHBJICOG_02374 1.2e-77 K DNA-templated transcription, initiation
HHBJICOG_02375 1.1e-25
HHBJICOG_02376 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHBJICOG_02377 4.7e-72 S SLAP domain
HHBJICOG_02378 5e-72 L Transposase
HHBJICOG_02379 4.3e-136 S Alpha/beta hydrolase family
HHBJICOG_02380 3.8e-139 pnuC H nicotinamide mononucleotide transporter
HHBJICOG_02381 7.3e-184 S cog cog1373
HHBJICOG_02382 1.6e-105 tag 3.2.2.20 L glycosylase
HHBJICOG_02383 3.9e-84
HHBJICOG_02384 1.6e-271 S Calcineurin-like phosphoesterase
HHBJICOG_02385 0.0 asnB 6.3.5.4 E Asparagine synthase
HHBJICOG_02386 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HHBJICOG_02387 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HHBJICOG_02388 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHBJICOG_02389 2.1e-103 S Iron-sulfur cluster assembly protein
HHBJICOG_02390 9.8e-230 XK27_04775 S PAS domain
HHBJICOG_02391 2.3e-210 yttB EGP Major facilitator Superfamily
HHBJICOG_02392 0.0 pepO 3.4.24.71 O Peptidase family M13
HHBJICOG_02393 0.0 kup P Transport of potassium into the cell
HHBJICOG_02394 6.3e-65
HHBJICOG_02395 2.1e-45 S PFAM Archaeal ATPase
HHBJICOG_02397 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HHBJICOG_02398 5.9e-45
HHBJICOG_02399 1.1e-33 S Domain of unknown function (DUF4417)
HHBJICOG_02400 1.3e-19
HHBJICOG_02401 2.5e-20
HHBJICOG_02402 1.1e-14 K Helix-turn-helix XRE-family like proteins
HHBJICOG_02403 3.1e-26 E Zn peptidase
HHBJICOG_02405 2.9e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HHBJICOG_02407 8.3e-24 S CAAX protease self-immunity
HHBJICOG_02409 4.1e-34
HHBJICOG_02410 3.9e-66 doc S Fic/DOC family
HHBJICOG_02412 2.5e-241 V N-6 DNA Methylase
HHBJICOG_02413 1.2e-85 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HHBJICOG_02414 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HHBJICOG_02415 1.7e-39 relB L RelB antitoxin
HHBJICOG_02417 2.2e-97 D VirC1 protein
HHBJICOG_02418 5e-15 S Domain of Unknown Function with PDB structure (DUF3850)
HHBJICOG_02420 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
HHBJICOG_02421 5.8e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHBJICOG_02422 1.7e-198 pbpX V Beta-lactamase
HHBJICOG_02423 1.3e-230 nhaC C Na H antiporter NhaC
HHBJICOG_02424 4.5e-50
HHBJICOG_02425 1.2e-105 ybhL S Belongs to the BI1 family
HHBJICOG_02426 1.5e-65 K transcriptional regulator
HHBJICOG_02427 6.7e-18
HHBJICOG_02428 2.7e-171 yegS 2.7.1.107 G Lipid kinase
HHBJICOG_02429 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHBJICOG_02430 1.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHBJICOG_02431 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHBJICOG_02432 1.7e-202 camS S sex pheromone
HHBJICOG_02433 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHBJICOG_02434 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HHBJICOG_02435 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HHBJICOG_02437 4.8e-84 ydcK S Belongs to the SprT family
HHBJICOG_02438 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HHBJICOG_02439 3e-257 epsU S Polysaccharide biosynthesis protein
HHBJICOG_02440 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHBJICOG_02441 0.0 pacL 3.6.3.8 P P-type ATPase
HHBJICOG_02442 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHBJICOG_02443 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHBJICOG_02444 2.9e-204 csaB M Glycosyl transferases group 1
HHBJICOG_02445 1.2e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HHBJICOG_02446 1.1e-66 L Transposase and inactivated derivatives, IS30 family
HHBJICOG_02447 0.0 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HHBJICOG_02448 6.2e-36 licR 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
HHBJICOG_02449 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
HHBJICOG_02450 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HHBJICOG_02451 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HHBJICOG_02452 3.5e-71 yqeY S YqeY-like protein
HHBJICOG_02453 2.5e-175 phoH T phosphate starvation-inducible protein PhoH
HHBJICOG_02454 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHBJICOG_02455 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHBJICOG_02456 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
HHBJICOG_02457 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HHBJICOG_02458 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HHBJICOG_02459 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHBJICOG_02460 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHBJICOG_02461 5.6e-128 2.7.1.202 GKT Mga helix-turn-helix domain
HHBJICOG_02462 5.9e-13 K Acetyltransferase (GNAT) domain
HHBJICOG_02463 1.9e-12 L Transposase
HHBJICOG_02464 1.4e-16 L Transposase
HHBJICOG_02465 7.8e-160 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HHBJICOG_02466 8.1e-38 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HHBJICOG_02467 5.2e-68 L haloacid dehalogenase-like hydrolase
HHBJICOG_02468 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HHBJICOG_02469 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HHBJICOG_02470 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HHBJICOG_02471 1.8e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HHBJICOG_02472 1.3e-231 ulaA S PTS system sugar-specific permease component
HHBJICOG_02473 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHBJICOG_02474 8.1e-175 ulaG S Beta-lactamase superfamily domain
HHBJICOG_02476 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHBJICOG_02477 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HHBJICOG_02478 2.2e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HHBJICOG_02479 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HHBJICOG_02480 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HHBJICOG_02481 2.4e-10 L Psort location Cytoplasmic, score
HHBJICOG_02482 1.7e-82 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HHBJICOG_02483 1.1e-67 L Transposase and inactivated derivatives, IS30 family
HHBJICOG_02484 3.5e-205 G Glycosyl hydrolases family 8
HHBJICOG_02485 1.3e-246 ydaM M Glycosyl transferase
HHBJICOG_02487 1.7e-151

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)