ORF_ID e_value Gene_name EC_number CAZy COGs Description
HFGJIHDG_00001 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFGJIHDG_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFGJIHDG_00003 2.4e-33 yaaA S S4 domain
HFGJIHDG_00004 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFGJIHDG_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
HFGJIHDG_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFGJIHDG_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFGJIHDG_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
HFGJIHDG_00013 3.3e-183 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HFGJIHDG_00014 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HFGJIHDG_00015 2.9e-93 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HFGJIHDG_00016 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HFGJIHDG_00017 7.3e-110 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFGJIHDG_00018 9.5e-62 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFGJIHDG_00019 4.1e-11 ydiF S ABC transporter
HFGJIHDG_00020 6.9e-49 ydiF S ABC transporter
HFGJIHDG_00021 4.7e-62 ydiF S ABC transporter
HFGJIHDG_00022 2.7e-135 ydiF S ABC transporter
HFGJIHDG_00023 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HFGJIHDG_00024 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFGJIHDG_00025 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HFGJIHDG_00026 9.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HFGJIHDG_00027 1.7e-27 ydiK S Domain of unknown function (DUF4305)
HFGJIHDG_00028 4.3e-127 ydiL S CAAX protease self-immunity
HFGJIHDG_00029 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFGJIHDG_00030 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFGJIHDG_00031 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
HFGJIHDG_00034 2.6e-62
HFGJIHDG_00035 0.0 K NB-ARC domain
HFGJIHDG_00036 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
HFGJIHDG_00037 1.1e-248 gutA G MFS/sugar transport protein
HFGJIHDG_00038 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HFGJIHDG_00039 1.2e-30 yjdJ S Domain of unknown function (DUF4306)
HFGJIHDG_00040 1.3e-112 pspA KT Phage shock protein A
HFGJIHDG_00041 1.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFGJIHDG_00042 1.1e-117 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HFGJIHDG_00043 5.3e-144 ydjI S virion core protein (lumpy skin disease virus)
HFGJIHDG_00044 0.0 yrhL I Acyltransferase family
HFGJIHDG_00045 1.4e-145 rsiV S Protein of unknown function (DUF3298)
HFGJIHDG_00046 1.2e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HFGJIHDG_00047 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HFGJIHDG_00048 1.2e-61 ydjM M Lytic transglycolase
HFGJIHDG_00049 2e-133 ydjN U Involved in the tonB-independent uptake of proteins
HFGJIHDG_00051 7.2e-35 ydjO S Cold-inducible protein YdjO
HFGJIHDG_00052 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HFGJIHDG_00053 4.8e-244 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HFGJIHDG_00054 1.5e-175 yeaC S COG0714 MoxR-like ATPases
HFGJIHDG_00055 3.3e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HFGJIHDG_00056 0.0 yebA E COG1305 Transglutaminase-like enzymes
HFGJIHDG_00057 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HFGJIHDG_00058 1.1e-92 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HFGJIHDG_00059 2.1e-247 S Domain of unknown function (DUF4179)
HFGJIHDG_00060 8.1e-209 pbuG S permease
HFGJIHDG_00061 1.5e-125 yebC M Membrane
HFGJIHDG_00063 7.5e-92 yebE S UPF0316 protein
HFGJIHDG_00064 5.5e-29 yebG S NETI protein
HFGJIHDG_00065 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFGJIHDG_00066 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFGJIHDG_00067 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFGJIHDG_00068 7e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HFGJIHDG_00069 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFGJIHDG_00070 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFGJIHDG_00071 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFGJIHDG_00072 4.4e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFGJIHDG_00073 1.1e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HFGJIHDG_00074 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFGJIHDG_00075 5.6e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HFGJIHDG_00076 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
HFGJIHDG_00077 2.6e-25 S Protein of unknown function (DUF2892)
HFGJIHDG_00078 0.0 yerA 3.5.4.2 F adenine deaminase
HFGJIHDG_00079 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
HFGJIHDG_00080 2.4e-50 yerC S protein conserved in bacteria
HFGJIHDG_00081 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HFGJIHDG_00082 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HFGJIHDG_00083 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HFGJIHDG_00084 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFGJIHDG_00085 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
HFGJIHDG_00086 6.8e-192 yerI S homoserine kinase type II (protein kinase fold)
HFGJIHDG_00087 1.3e-120 sapB S MgtC SapB transporter
HFGJIHDG_00088 1.4e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFGJIHDG_00089 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFGJIHDG_00090 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFGJIHDG_00091 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFGJIHDG_00092 1.3e-151 yerO K Transcriptional regulator
HFGJIHDG_00093 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HFGJIHDG_00094 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HFGJIHDG_00095 3.9e-246 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFGJIHDG_00096 4.5e-21
HFGJIHDG_00097 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HFGJIHDG_00098 2.2e-138 cylB V ABC-2 type transporter
HFGJIHDG_00099 2.7e-85 S Protein of unknown function, DUF600
HFGJIHDG_00100 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
HFGJIHDG_00101 1.2e-19
HFGJIHDG_00102 9.4e-127 yeeN K transcriptional regulatory protein
HFGJIHDG_00104 4.5e-107 aadK G Streptomycin adenylyltransferase
HFGJIHDG_00105 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
HFGJIHDG_00106 1.3e-44 cotJB S CotJB protein
HFGJIHDG_00107 8.9e-104 cotJC P Spore Coat
HFGJIHDG_00108 5e-93 yesJ K Acetyltransferase (GNAT) family
HFGJIHDG_00110 2.1e-120 yetF S membrane
HFGJIHDG_00111 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HFGJIHDG_00112 3.4e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFGJIHDG_00113 2.4e-153 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFGJIHDG_00114 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
HFGJIHDG_00115 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
HFGJIHDG_00116 2.6e-104 yetJ S Belongs to the BI1 family
HFGJIHDG_00117 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_00118 7.9e-205 yetM CH FAD binding domain
HFGJIHDG_00119 7.5e-197 yetN S Protein of unknown function (DUF3900)
HFGJIHDG_00120 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HFGJIHDG_00121 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HFGJIHDG_00122 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HFGJIHDG_00123 7.1e-172 yfnG 4.2.1.45 M dehydratase
HFGJIHDG_00124 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
HFGJIHDG_00125 1.4e-220 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HFGJIHDG_00126 1.5e-185 yfnD M Nucleotide-diphospho-sugar transferase
HFGJIHDG_00127 6.8e-218 fsr P COG0477 Permeases of the major facilitator superfamily
HFGJIHDG_00128 3e-246 yfnA E amino acid
HFGJIHDG_00129 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFGJIHDG_00130 7.5e-107 yfmS NT chemotaxis protein
HFGJIHDG_00131 5.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
HFGJIHDG_00132 1.2e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HFGJIHDG_00133 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFGJIHDG_00134 1.8e-69 yfmP K transcriptional
HFGJIHDG_00135 7.5e-206 yfmO EGP Major facilitator Superfamily
HFGJIHDG_00136 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFGJIHDG_00137 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HFGJIHDG_00138 2.1e-41 yfmK 2.3.1.128 K acetyltransferase
HFGJIHDG_00139 1.4e-187 yfmJ S N-terminal domain of oxidoreductase
HFGJIHDG_00140 2.7e-24 S Protein of unknown function (DUF3212)
HFGJIHDG_00141 1.3e-57 yflT S Heat induced stress protein YflT
HFGJIHDG_00142 1.7e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HFGJIHDG_00143 6e-234 yflS P Sodium:sulfate symporter transmembrane region
HFGJIHDG_00144 5.2e-27 Q PFAM Collagen triple helix
HFGJIHDG_00146 3.3e-23 M1-820 Q Collagen triple helix repeat (20 copies)
HFGJIHDG_00147 6.8e-24 M1-820 Q Collagen triple helix repeat (20 copies)
HFGJIHDG_00148 0.0 ywpD T PhoQ Sensor
HFGJIHDG_00149 1.3e-151 M1-574 T Transcriptional regulatory protein, C terminal
HFGJIHDG_00150 0.0 M1-568 M cell wall anchor domain
HFGJIHDG_00151 3.5e-80 srtA 3.4.22.70 M Sortase family
HFGJIHDG_00152 6.2e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HFGJIHDG_00153 2.6e-118 citT T response regulator
HFGJIHDG_00154 1.7e-176 yflP S Tripartite tricarboxylate transporter family receptor
HFGJIHDG_00155 3.6e-225 citM C Citrate transporter
HFGJIHDG_00156 4.8e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HFGJIHDG_00157 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HFGJIHDG_00158 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HFGJIHDG_00159 1.3e-122 yflK S protein conserved in bacteria
HFGJIHDG_00160 1.5e-14 yflJ S Protein of unknown function (DUF2639)
HFGJIHDG_00161 7e-19 yflI
HFGJIHDG_00162 3.1e-50 yflH S Protein of unknown function (DUF3243)
HFGJIHDG_00163 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
HFGJIHDG_00164 2.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HFGJIHDG_00165 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
HFGJIHDG_00166 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HFGJIHDG_00167 2.5e-62 yhdN S Domain of unknown function (DUF1992)
HFGJIHDG_00168 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
HFGJIHDG_00169 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
HFGJIHDG_00170 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
HFGJIHDG_00171 1.1e-185 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFGJIHDG_00172 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HFGJIHDG_00173 2e-129 treR K transcriptional
HFGJIHDG_00174 1.2e-123 yfkO C nitroreductase
HFGJIHDG_00175 1e-123 yibF S YibE/F-like protein
HFGJIHDG_00176 5.5e-198 yibE S YibE/F-like protein
HFGJIHDG_00177 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HFGJIHDG_00178 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HFGJIHDG_00179 6.4e-185 K helix_turn _helix lactose operon repressor
HFGJIHDG_00180 4.3e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFGJIHDG_00181 3.4e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HFGJIHDG_00182 3.6e-192 ydiM EGP Major facilitator Superfamily
HFGJIHDG_00183 2.7e-29 yfkK S Belongs to the UPF0435 family
HFGJIHDG_00184 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFGJIHDG_00185 1.7e-51 yfkI S gas vesicle protein
HFGJIHDG_00186 7.6e-144 yihY S Belongs to the UPF0761 family
HFGJIHDG_00187 2.5e-07
HFGJIHDG_00188 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HFGJIHDG_00189 5.5e-184 cax P COG0387 Ca2 H antiporter
HFGJIHDG_00190 1e-142 yfkD S YfkD-like protein
HFGJIHDG_00191 1e-145 yfkC M Mechanosensitive ion channel
HFGJIHDG_00192 7.3e-219 yfkA S YfkB-like domain
HFGJIHDG_00193 4.9e-27 yfjT
HFGJIHDG_00194 9e-155 pdaA G deacetylase
HFGJIHDG_00195 6.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HFGJIHDG_00196 3.3e-30
HFGJIHDG_00197 8.5e-184 corA P Mediates influx of magnesium ions
HFGJIHDG_00198 2.8e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HFGJIHDG_00199 8.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFGJIHDG_00200 1.5e-43 S YfzA-like protein
HFGJIHDG_00201 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFGJIHDG_00202 3.7e-87 yfjM S Psort location Cytoplasmic, score
HFGJIHDG_00203 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFGJIHDG_00204 8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFGJIHDG_00205 7.1e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFGJIHDG_00206 2.3e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFGJIHDG_00207 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HFGJIHDG_00208 4.2e-15 sspH S Belongs to the SspH family
HFGJIHDG_00209 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HFGJIHDG_00210 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
HFGJIHDG_00211 8.3e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFGJIHDG_00212 7.4e-151 yfiB3 V ABC transporter
HFGJIHDG_00213 3.6e-143 yfiB3 V ABC transporter
HFGJIHDG_00214 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HFGJIHDG_00215 2e-62 mhqP S DoxX
HFGJIHDG_00216 1.1e-158 yfiE 1.13.11.2 S glyoxalase
HFGJIHDG_00217 1.1e-164 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HFGJIHDG_00218 1.9e-95 padR K transcriptional
HFGJIHDG_00219 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
HFGJIHDG_00220 1.9e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HFGJIHDG_00221 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
HFGJIHDG_00222 4.5e-45 yrdF K ribonuclease inhibitor
HFGJIHDG_00223 2.9e-96 yfiT S Belongs to the metal hydrolase YfiT family
HFGJIHDG_00224 1.1e-289 yfiU EGP Major facilitator Superfamily
HFGJIHDG_00225 6.2e-82 yfiV K transcriptional
HFGJIHDG_00226 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFGJIHDG_00227 7.2e-161 yfhB 5.3.3.17 S PhzF family
HFGJIHDG_00228 1.7e-105 yfhC C nitroreductase
HFGJIHDG_00229 2.1e-25 yfhD S YfhD-like protein
HFGJIHDG_00231 2.2e-165 yfhF S nucleoside-diphosphate sugar epimerase
HFGJIHDG_00232 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
HFGJIHDG_00233 2.5e-52 yfhH S Protein of unknown function (DUF1811)
HFGJIHDG_00234 1.1e-204 yfhI EGP Major facilitator Superfamily
HFGJIHDG_00236 5.3e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HFGJIHDG_00237 2.2e-44 yfhJ S WVELL protein
HFGJIHDG_00238 2.2e-93 batE T Bacterial SH3 domain homologues
HFGJIHDG_00239 4.8e-33 yfhL S SdpI/YhfL protein family
HFGJIHDG_00240 3.1e-169 yfhM S Alpha/beta hydrolase family
HFGJIHDG_00241 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HFGJIHDG_00242 0.0 yfhO S Bacterial membrane protein YfhO
HFGJIHDG_00243 1e-184 yfhP S membrane-bound metal-dependent
HFGJIHDG_00244 4.8e-207 mutY L A G-specific
HFGJIHDG_00245 3.1e-36 yfhS
HFGJIHDG_00246 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_00248 1.5e-37 ygaB S YgaB-like protein
HFGJIHDG_00249 2.2e-104 ygaC J Belongs to the UPF0374 family
HFGJIHDG_00250 9.1e-301 ygaD V ABC transporter
HFGJIHDG_00251 2.7e-178 ygaE S Membrane
HFGJIHDG_00252 2.3e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HFGJIHDG_00253 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
HFGJIHDG_00254 1.8e-80 perR P Belongs to the Fur family
HFGJIHDG_00255 1.5e-56 ygzB S UPF0295 protein
HFGJIHDG_00256 1.1e-164 ygxA S Nucleotidyltransferase-like
HFGJIHDG_00257 3.4e-39 S COG NOG14552 non supervised orthologous group
HFGJIHDG_00262 1.6e-08
HFGJIHDG_00269 1.3e-09
HFGJIHDG_00270 7.8e-08
HFGJIHDG_00279 2.6e-77 tspO T membrane
HFGJIHDG_00280 2.4e-130 dksA T COG1734 DnaK suppressor protein
HFGJIHDG_00281 5.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
HFGJIHDG_00282 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HFGJIHDG_00283 3.9e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HFGJIHDG_00284 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HFGJIHDG_00285 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HFGJIHDG_00286 1.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HFGJIHDG_00287 2e-23 S Domain of Unknown Function (DUF1540)
HFGJIHDG_00288 1.6e-183 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HFGJIHDG_00289 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
HFGJIHDG_00290 7.9e-41 rpmE2 J Ribosomal protein L31
HFGJIHDG_00291 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HFGJIHDG_00292 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HFGJIHDG_00293 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFGJIHDG_00294 5.7e-74 ytkA S YtkA-like
HFGJIHDG_00296 7.8e-76 dps P Belongs to the Dps family
HFGJIHDG_00297 5e-61 ytkC S Bacteriophage holin family
HFGJIHDG_00298 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HFGJIHDG_00299 6.9e-126 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HFGJIHDG_00300 3.2e-144 ytlC P ABC transporter
HFGJIHDG_00301 2.6e-183 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HFGJIHDG_00302 1.5e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HFGJIHDG_00303 1.6e-38 ytmB S Protein of unknown function (DUF2584)
HFGJIHDG_00304 4.5e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HFGJIHDG_00305 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFGJIHDG_00306 0.0 asnB 6.3.5.4 E Asparagine synthase
HFGJIHDG_00307 1.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HFGJIHDG_00308 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HFGJIHDG_00309 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
HFGJIHDG_00310 7.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HFGJIHDG_00311 1.5e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HFGJIHDG_00313 7.4e-106 ytqB J Putative rRNA methylase
HFGJIHDG_00314 1.1e-189 yhcC S Fe-S oxidoreductase
HFGJIHDG_00315 1.3e-39 ytzC S Protein of unknown function (DUF2524)
HFGJIHDG_00317 3.9e-66 ytrA K GntR family transcriptional regulator
HFGJIHDG_00318 1.9e-161 ytrB P abc transporter atp-binding protein
HFGJIHDG_00319 1.3e-163 S ABC-2 family transporter protein
HFGJIHDG_00320 3.5e-172 P ABC-2 family transporter protein
HFGJIHDG_00321 1.4e-152
HFGJIHDG_00322 2.2e-125 ytrE V ABC transporter, ATP-binding protein
HFGJIHDG_00323 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HFGJIHDG_00324 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_00325 8.7e-179 T PhoQ Sensor
HFGJIHDG_00326 4.9e-134 bceA V ABC transporter, ATP-binding protein
HFGJIHDG_00327 0.0 bceB V ABC transporter (permease)
HFGJIHDG_00328 1.4e-122 ywaF S Integral membrane protein
HFGJIHDG_00329 2.3e-207 yttB EGP Major facilitator Superfamily
HFGJIHDG_00330 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HFGJIHDG_00331 1.2e-52 ytvB S Protein of unknown function (DUF4257)
HFGJIHDG_00332 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFGJIHDG_00333 5.6e-52 ytwF P Sulfurtransferase
HFGJIHDG_00334 1.7e-84 M Acetyltransferase (GNAT) domain
HFGJIHDG_00335 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HFGJIHDG_00336 1.8e-142 amyC P ABC transporter (permease)
HFGJIHDG_00337 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
HFGJIHDG_00338 4.9e-243 msmE G Bacterial extracellular solute-binding protein
HFGJIHDG_00339 4.8e-185 msmR K Transcriptional regulator
HFGJIHDG_00340 9e-26 yteV S Sporulation protein Cse60
HFGJIHDG_00341 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HFGJIHDG_00342 5.7e-236 ytfP S HI0933-like protein
HFGJIHDG_00343 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFGJIHDG_00344 2.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFGJIHDG_00345 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HFGJIHDG_00346 3.7e-128 ythP V ABC transporter
HFGJIHDG_00347 4.6e-216 ythQ U Bacterial ABC transporter protein EcsB
HFGJIHDG_00348 1.3e-227 pbuO S permease
HFGJIHDG_00349 3.1e-267 pepV 3.5.1.18 E Dipeptidase
HFGJIHDG_00350 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFGJIHDG_00351 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HFGJIHDG_00352 1.3e-165 ytlQ
HFGJIHDG_00353 1.5e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HFGJIHDG_00354 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
HFGJIHDG_00355 3.5e-45 ytzH S YtzH-like protein
HFGJIHDG_00356 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFGJIHDG_00357 6.2e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HFGJIHDG_00358 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HFGJIHDG_00359 1.7e-51 ytzB S small secreted protein
HFGJIHDG_00360 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HFGJIHDG_00361 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HFGJIHDG_00362 7.9e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HFGJIHDG_00363 3.7e-148 ytpQ S Belongs to the UPF0354 family
HFGJIHDG_00364 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFGJIHDG_00365 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HFGJIHDG_00366 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HFGJIHDG_00367 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFGJIHDG_00368 1.7e-16 ytxH S COG4980 Gas vesicle protein
HFGJIHDG_00369 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
HFGJIHDG_00370 1.2e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HFGJIHDG_00371 6.4e-182 ccpA K catabolite control protein A
HFGJIHDG_00372 6.6e-145 motA N flagellar motor
HFGJIHDG_00373 4.8e-120 motS N Flagellar motor protein
HFGJIHDG_00374 9e-228 acuC BQ histone deacetylase
HFGJIHDG_00375 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HFGJIHDG_00376 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HFGJIHDG_00377 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HFGJIHDG_00378 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFGJIHDG_00379 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
HFGJIHDG_00380 2e-124 azlC E AzlC protein
HFGJIHDG_00381 2.8e-148 K Transcriptional regulator
HFGJIHDG_00382 8.1e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFGJIHDG_00383 1.5e-135 E GDSL-like Lipase/Acylhydrolase family
HFGJIHDG_00385 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HFGJIHDG_00386 2.5e-09
HFGJIHDG_00387 9.2e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFGJIHDG_00388 1.7e-99 yokH G SMI1 / KNR4 family
HFGJIHDG_00389 5.5e-253 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HFGJIHDG_00390 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFGJIHDG_00391 2.3e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HFGJIHDG_00392 1.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
HFGJIHDG_00393 3.8e-108 yttP K Transcriptional regulator
HFGJIHDG_00394 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HFGJIHDG_00395 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFGJIHDG_00396 2.2e-238 braB E Component of the transport system for branched-chain amino acids
HFGJIHDG_00397 6.6e-207 iscS2 2.8.1.7 E Cysteine desulfurase
HFGJIHDG_00398 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFGJIHDG_00399 3.9e-31 sspB S spore protein
HFGJIHDG_00400 4.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HFGJIHDG_00401 0.0 ytcJ S amidohydrolase
HFGJIHDG_00402 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFGJIHDG_00403 6.4e-182 sppA OU signal peptide peptidase SppA
HFGJIHDG_00404 4.5e-88 yteJ S RDD family
HFGJIHDG_00405 1e-93 ytfI S Protein of unknown function (DUF2953)
HFGJIHDG_00406 1.6e-60 ytfJ S Sporulation protein YtfJ
HFGJIHDG_00407 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HFGJIHDG_00408 2e-180 ytxK 2.1.1.72 L DNA methylase
HFGJIHDG_00409 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFGJIHDG_00410 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HFGJIHDG_00411 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFGJIHDG_00412 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
HFGJIHDG_00414 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_00415 1.3e-128 ytkL S Belongs to the UPF0173 family
HFGJIHDG_00416 1.6e-236 ytoI K transcriptional regulator containing CBS domains
HFGJIHDG_00417 1.5e-46 ytpI S YtpI-like protein
HFGJIHDG_00418 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HFGJIHDG_00419 5.8e-23
HFGJIHDG_00420 4.3e-86 ytrI
HFGJIHDG_00421 3.2e-56 ytrH S Sporulation protein YtrH
HFGJIHDG_00422 0.0 dnaE 2.7.7.7 L DNA polymerase
HFGJIHDG_00423 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
HFGJIHDG_00424 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFGJIHDG_00425 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HFGJIHDG_00426 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFGJIHDG_00427 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HFGJIHDG_00428 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HFGJIHDG_00429 6.9e-193 ytvI S sporulation integral membrane protein YtvI
HFGJIHDG_00430 1.1e-72 yeaL S membrane
HFGJIHDG_00431 2.1e-46 yjdF S Protein of unknown function (DUF2992)
HFGJIHDG_00432 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HFGJIHDG_00433 2.7e-241 icd 1.1.1.42 C isocitrate
HFGJIHDG_00434 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HFGJIHDG_00435 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_00436 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HFGJIHDG_00437 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFGJIHDG_00438 9.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFGJIHDG_00439 6.2e-106 ytaF P Probably functions as a manganese efflux pump
HFGJIHDG_00440 2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFGJIHDG_00441 1.7e-159 ytbE S reductase
HFGJIHDG_00442 4.5e-206 ytbD EGP Major facilitator Superfamily
HFGJIHDG_00443 2e-67 ytcD K Transcriptional regulator
HFGJIHDG_00444 2.2e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFGJIHDG_00445 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HFGJIHDG_00446 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFGJIHDG_00447 3.1e-251 dnaB L Membrane attachment protein
HFGJIHDG_00448 9.5e-172 dnaI L Primosomal protein DnaI
HFGJIHDG_00449 2.1e-106 ytxB S SNARE associated Golgi protein
HFGJIHDG_00450 6.7e-153 ytxC S YtxC-like family
HFGJIHDG_00451 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFGJIHDG_00452 8.7e-150 ysaA S HAD-hyrolase-like
HFGJIHDG_00453 0.0 lytS 2.7.13.3 T Histidine kinase
HFGJIHDG_00454 2.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HFGJIHDG_00455 2.9e-38 lrgA S effector of murein hydrolase LrgA
HFGJIHDG_00456 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HFGJIHDG_00457 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFGJIHDG_00458 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HFGJIHDG_00459 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFGJIHDG_00460 2.6e-42 ysdA S Membrane
HFGJIHDG_00461 1.9e-65 ysdB S Sigma-w pathway protein YsdB
HFGJIHDG_00462 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
HFGJIHDG_00463 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HFGJIHDG_00464 4.4e-296 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HFGJIHDG_00465 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HFGJIHDG_00466 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HFGJIHDG_00467 7.8e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HFGJIHDG_00468 4.4e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HFGJIHDG_00469 2.9e-251 araN G carbohydrate transport
HFGJIHDG_00470 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
HFGJIHDG_00471 1.2e-144 araQ G transport system permease
HFGJIHDG_00472 8.6e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HFGJIHDG_00473 0.0 cstA T Carbon starvation protein
HFGJIHDG_00474 8.9e-256 glcF C Glycolate oxidase
HFGJIHDG_00475 1.6e-258 glcD 1.1.3.15 C FAD binding domain
HFGJIHDG_00476 2.7e-202 ysfB KT regulator
HFGJIHDG_00477 2e-32 sspI S Belongs to the SspI family
HFGJIHDG_00478 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFGJIHDG_00479 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFGJIHDG_00480 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFGJIHDG_00481 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFGJIHDG_00482 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HFGJIHDG_00483 3.6e-83 cvpA S membrane protein, required for colicin V production
HFGJIHDG_00484 0.0 polX L COG1796 DNA polymerase IV (family X)
HFGJIHDG_00485 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFGJIHDG_00486 4.7e-67 yshE S membrane
HFGJIHDG_00487 1.6e-115 ywbB S Protein of unknown function (DUF2711)
HFGJIHDG_00488 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HFGJIHDG_00489 2.7e-103 fadR K Transcriptional regulator
HFGJIHDG_00490 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HFGJIHDG_00491 1.7e-137 etfB C Electron transfer flavoprotein
HFGJIHDG_00492 1.6e-177 etfA C Electron transfer flavoprotein
HFGJIHDG_00493 4.3e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HFGJIHDG_00494 2.5e-52 trxA O Belongs to the thioredoxin family
HFGJIHDG_00495 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFGJIHDG_00496 1.6e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HFGJIHDG_00497 2e-79 yslB S Protein of unknown function (DUF2507)
HFGJIHDG_00498 4.8e-108 sdhC C succinate dehydrogenase
HFGJIHDG_00499 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HFGJIHDG_00500 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HFGJIHDG_00501 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HFGJIHDG_00502 2e-30 gerE K Transcriptional regulator
HFGJIHDG_00503 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_00504 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFGJIHDG_00505 5.8e-197 gerM S COG5401 Spore germination protein
HFGJIHDG_00506 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HFGJIHDG_00507 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFGJIHDG_00508 5.9e-91 ysnB S Phosphoesterase
HFGJIHDG_00513 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HFGJIHDG_00514 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
HFGJIHDG_00515 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HFGJIHDG_00516 7.9e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HFGJIHDG_00517 2.4e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HFGJIHDG_00518 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFGJIHDG_00519 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFGJIHDG_00520 1.6e-188 ysoA H Tetratricopeptide repeat
HFGJIHDG_00521 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFGJIHDG_00522 8.5e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFGJIHDG_00523 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HFGJIHDG_00524 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HFGJIHDG_00525 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HFGJIHDG_00526 3.8e-87 ysxD
HFGJIHDG_00527 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HFGJIHDG_00528 1e-145 hemX O cytochrome C
HFGJIHDG_00529 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HFGJIHDG_00530 1.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HFGJIHDG_00531 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
HFGJIHDG_00532 2e-244 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HFGJIHDG_00533 1.6e-218 spoVID M stage VI sporulation protein D
HFGJIHDG_00534 3.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HFGJIHDG_00535 2.1e-25
HFGJIHDG_00536 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFGJIHDG_00537 4.8e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFGJIHDG_00538 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HFGJIHDG_00539 2.8e-137 spoIIB S Sporulation related domain
HFGJIHDG_00540 2.1e-97 maf D septum formation protein Maf
HFGJIHDG_00541 1.8e-127 radC E Belongs to the UPF0758 family
HFGJIHDG_00542 4e-184 mreB D Rod shape-determining protein MreB
HFGJIHDG_00543 3.6e-157 mreC M Involved in formation and maintenance of cell shape
HFGJIHDG_00544 5.4e-84 mreD M shape-determining protein
HFGJIHDG_00545 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HFGJIHDG_00546 2.3e-142 minD D Belongs to the ParA family
HFGJIHDG_00547 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HFGJIHDG_00548 4.6e-160 spoIVFB S Stage IV sporulation protein
HFGJIHDG_00549 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HFGJIHDG_00550 7e-56 ysxB J ribosomal protein
HFGJIHDG_00551 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HFGJIHDG_00552 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HFGJIHDG_00553 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFGJIHDG_00554 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HFGJIHDG_00555 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
HFGJIHDG_00556 1.3e-93 niaR S small molecule binding protein (contains 3H domain)
HFGJIHDG_00557 2.1e-221 nifS 2.8.1.7 E Cysteine desulfurase
HFGJIHDG_00558 5.7e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HFGJIHDG_00559 7.6e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HFGJIHDG_00560 2.2e-212 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HFGJIHDG_00561 2.1e-115 safA M spore coat assembly protein SafA
HFGJIHDG_00562 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFGJIHDG_00564 3.7e-93 bofC S BofC C-terminal domain
HFGJIHDG_00565 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFGJIHDG_00566 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFGJIHDG_00567 2.8e-20 yrzS S Protein of unknown function (DUF2905)
HFGJIHDG_00568 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HFGJIHDG_00569 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFGJIHDG_00570 2.5e-37 yajC U Preprotein translocase subunit YajC
HFGJIHDG_00571 2.4e-60 yrzE S Protein of unknown function (DUF3792)
HFGJIHDG_00572 9.5e-110 yrbG S membrane
HFGJIHDG_00573 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFGJIHDG_00574 8.5e-50 yrzD S Post-transcriptional regulator
HFGJIHDG_00575 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HFGJIHDG_00576 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HFGJIHDG_00577 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
HFGJIHDG_00578 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HFGJIHDG_00579 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFGJIHDG_00580 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFGJIHDG_00581 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFGJIHDG_00582 8.5e-274 lytH 3.5.1.28 M COG3103 SH3 domain protein
HFGJIHDG_00585 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HFGJIHDG_00586 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HFGJIHDG_00587 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HFGJIHDG_00588 2.4e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HFGJIHDG_00589 7.8e-64 cymR K Transcriptional regulator
HFGJIHDG_00590 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
HFGJIHDG_00591 2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFGJIHDG_00592 1.7e-18 S COG0457 FOG TPR repeat
HFGJIHDG_00593 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFGJIHDG_00594 3.4e-82 yrrD S protein conserved in bacteria
HFGJIHDG_00595 2.9e-30 yrzR
HFGJIHDG_00596 2.1e-08 S Protein of unknown function (DUF3918)
HFGJIHDG_00597 1.4e-105 glnP P ABC transporter
HFGJIHDG_00598 6.1e-109 gluC P ABC transporter
HFGJIHDG_00599 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
HFGJIHDG_00600 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HFGJIHDG_00601 4.3e-160 yrrI S AI-2E family transporter
HFGJIHDG_00602 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFGJIHDG_00603 8.5e-41 yrzL S Belongs to the UPF0297 family
HFGJIHDG_00604 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFGJIHDG_00605 7.1e-46 yrzB S Belongs to the UPF0473 family
HFGJIHDG_00606 4.1e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFGJIHDG_00607 2.3e-116 yrrM 2.1.1.104 S O-methyltransferase
HFGJIHDG_00608 2.9e-173 yegQ O Peptidase U32
HFGJIHDG_00609 6.1e-246 yegQ O COG0826 Collagenase and related proteases
HFGJIHDG_00610 3.4e-112 udk 2.7.1.48 F Cytidine monophosphokinase
HFGJIHDG_00611 2.7e-67 L Arm DNA-binding domain
HFGJIHDG_00612 5.5e-44
HFGJIHDG_00614 2.5e-25 K Helix-turn-helix XRE-family like proteins
HFGJIHDG_00617 5.7e-70 L dnaD_dom DnaD domain protein
HFGJIHDG_00618 4.8e-42 dnaC L IstB-like ATP binding protein
HFGJIHDG_00620 3.7e-07
HFGJIHDG_00621 5.8e-28
HFGJIHDG_00624 6.1e-15 yqaO S Phage-like element PBSX protein XtrA
HFGJIHDG_00627 1.2e-27
HFGJIHDG_00629 1.2e-167 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HFGJIHDG_00630 2e-125 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HFGJIHDG_00633 2.4e-43 S dUTPase
HFGJIHDG_00636 1.5e-47
HFGJIHDG_00637 3e-42 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HFGJIHDG_00638 9.6e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
HFGJIHDG_00639 8.8e-77 L Phage integrase family
HFGJIHDG_00642 5.9e-25
HFGJIHDG_00644 5.2e-79 L phage terminase small subunit
HFGJIHDG_00645 2.2e-299 S Terminase
HFGJIHDG_00646 1.2e-169 S Phage portal protein
HFGJIHDG_00647 6.6e-84 S peptidase activity
HFGJIHDG_00648 1.2e-153 gp36 S capsid protein
HFGJIHDG_00649 3.1e-23
HFGJIHDG_00650 1.1e-39 S Phage gp6-like head-tail connector protein
HFGJIHDG_00651 5e-40 S Phage head-tail joining protein
HFGJIHDG_00652 1.3e-48 S Bacteriophage HK97-gp10, putative tail-component
HFGJIHDG_00654 1.2e-77 S Phage tail tube protein
HFGJIHDG_00656 0.0 D phage tail tape measure protein
HFGJIHDG_00657 4.5e-104 S Phage tail protein
HFGJIHDG_00658 8.2e-230 NU Prophage endopeptidase tail
HFGJIHDG_00659 0.0 M Pectate lyase superfamily protein
HFGJIHDG_00660 3.5e-148 S Domain of unknown function (DUF2479)
HFGJIHDG_00663 6e-65 S Pfam:Phage_holin_4_1
HFGJIHDG_00664 1e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HFGJIHDG_00665 4.5e-07
HFGJIHDG_00668 1.1e-07
HFGJIHDG_00669 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFGJIHDG_00670 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HFGJIHDG_00671 8.1e-70 yrrS S Protein of unknown function (DUF1510)
HFGJIHDG_00672 1.6e-26 yrzA S Protein of unknown function (DUF2536)
HFGJIHDG_00673 2.1e-117 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HFGJIHDG_00674 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFGJIHDG_00675 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HFGJIHDG_00676 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HFGJIHDG_00677 5.1e-34 yrhC S YrhC-like protein
HFGJIHDG_00678 4.5e-80 yrhD S Protein of unknown function (DUF1641)
HFGJIHDG_00679 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HFGJIHDG_00680 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
HFGJIHDG_00681 8e-143 focA P Formate nitrite
HFGJIHDG_00683 7.1e-79 yrhH Q methyltransferase
HFGJIHDG_00684 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HFGJIHDG_00685 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HFGJIHDG_00686 5.5e-212 ynfM EGP Major facilitator Superfamily
HFGJIHDG_00687 4.1e-164 yybE K Transcriptional regulator
HFGJIHDG_00688 1.1e-78 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFGJIHDG_00689 2.1e-179 romA S Beta-lactamase superfamily domain
HFGJIHDG_00690 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HFGJIHDG_00691 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HFGJIHDG_00692 1.7e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
HFGJIHDG_00693 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
HFGJIHDG_00694 1.6e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HFGJIHDG_00695 4.2e-144 S hydrolase
HFGJIHDG_00697 1.5e-91 yrdA S DinB family
HFGJIHDG_00698 4.3e-81 yyaR K Acetyltransferase (GNAT) domain
HFGJIHDG_00699 1.4e-219 tetL EGP Major facilitator Superfamily
HFGJIHDG_00701 4.9e-96 adk 2.7.4.3 F adenylate kinase activity
HFGJIHDG_00702 1e-146 ydeE K AraC family transcriptional regulator
HFGJIHDG_00703 3.6e-91 K Transcriptional regulator PadR-like family
HFGJIHDG_00704 6e-157 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HFGJIHDG_00705 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFGJIHDG_00706 1.1e-199 EGP Major facilitator Superfamily
HFGJIHDG_00707 8e-106 yqeD S SNARE associated Golgi protein
HFGJIHDG_00708 2.9e-139 3.5.1.104 G Polysaccharide deacetylase
HFGJIHDG_00709 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
HFGJIHDG_00711 7.6e-94 yqeG S hydrolase of the HAD superfamily
HFGJIHDG_00712 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HFGJIHDG_00713 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFGJIHDG_00714 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HFGJIHDG_00715 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFGJIHDG_00716 1.6e-100 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HFGJIHDG_00717 2.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFGJIHDG_00718 1.1e-138 yqeM Q Methyltransferase
HFGJIHDG_00719 6.5e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFGJIHDG_00720 9.6e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HFGJIHDG_00721 8e-105 comEB 3.5.4.12 F ComE operon protein 2
HFGJIHDG_00722 0.0 comEC S Competence protein ComEC
HFGJIHDG_00723 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
HFGJIHDG_00724 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
HFGJIHDG_00725 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HFGJIHDG_00726 7.8e-219 spoIIP M stage II sporulation protein P
HFGJIHDG_00727 2.5e-53 yqxA S Protein of unknown function (DUF3679)
HFGJIHDG_00728 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFGJIHDG_00729 2.2e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HFGJIHDG_00730 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFGJIHDG_00731 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFGJIHDG_00732 0.0 dnaK O Heat shock 70 kDa protein
HFGJIHDG_00733 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFGJIHDG_00734 6.6e-173 prmA J Methylates ribosomal protein L11
HFGJIHDG_00735 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFGJIHDG_00736 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HFGJIHDG_00737 4.8e-155 yqeW P COG1283 Na phosphate symporter
HFGJIHDG_00738 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HFGJIHDG_00739 8e-68 yqeY S Yqey-like protein
HFGJIHDG_00740 3.1e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HFGJIHDG_00741 3.8e-118 yqfA S UPF0365 protein
HFGJIHDG_00742 1.9e-42 yqfB
HFGJIHDG_00743 9.3e-46 yqfC S sporulation protein YqfC
HFGJIHDG_00744 1.7e-213 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HFGJIHDG_00745 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
HFGJIHDG_00746 0.0 yqfF S membrane-associated HD superfamily hydrolase
HFGJIHDG_00747 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFGJIHDG_00748 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HFGJIHDG_00749 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HFGJIHDG_00750 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFGJIHDG_00751 1.8e-16 S YqzL-like protein
HFGJIHDG_00752 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
HFGJIHDG_00753 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HFGJIHDG_00754 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HFGJIHDG_00755 4.5e-112 ccpN K CBS domain
HFGJIHDG_00756 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFGJIHDG_00757 1.3e-87 yaiI S Belongs to the UPF0178 family
HFGJIHDG_00758 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFGJIHDG_00759 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFGJIHDG_00760 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
HFGJIHDG_00761 2.9e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HFGJIHDG_00762 1.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFGJIHDG_00763 6.5e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HFGJIHDG_00764 3.7e-43 yqfQ S YqfQ-like protein
HFGJIHDG_00765 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFGJIHDG_00766 2.8e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HFGJIHDG_00767 4.6e-36 yqfT S Protein of unknown function (DUF2624)
HFGJIHDG_00768 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HFGJIHDG_00769 2.9e-72 zur P Belongs to the Fur family
HFGJIHDG_00770 3.2e-109 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HFGJIHDG_00771 2.3e-52 yqfX S membrane
HFGJIHDG_00772 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HFGJIHDG_00773 3.1e-47 yqfZ M LysM domain
HFGJIHDG_00774 1.8e-128 yqgB S Protein of unknown function (DUF1189)
HFGJIHDG_00775 2.2e-71 yqgC S protein conserved in bacteria
HFGJIHDG_00776 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HFGJIHDG_00777 3.4e-228 yqgE EGP Major facilitator superfamily
HFGJIHDG_00778 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HFGJIHDG_00779 8.4e-157 pstS P Phosphate
HFGJIHDG_00780 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
HFGJIHDG_00781 2.9e-154 pstA P Phosphate transport system permease
HFGJIHDG_00782 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFGJIHDG_00783 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFGJIHDG_00784 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFGJIHDG_00785 1.2e-50 yqzD
HFGJIHDG_00786 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFGJIHDG_00787 4.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFGJIHDG_00788 4e-07 yqgO
HFGJIHDG_00789 5.7e-212 nhaC C Na H antiporter
HFGJIHDG_00790 2.2e-179 glcK 2.7.1.2 G Glucokinase
HFGJIHDG_00791 1.2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HFGJIHDG_00792 4.3e-197 yqgU
HFGJIHDG_00793 6.9e-50 yqgV S Thiamine-binding protein
HFGJIHDG_00794 5.4e-20 yqgW S Protein of unknown function (DUF2759)
HFGJIHDG_00795 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HFGJIHDG_00796 3.1e-37 yqgY S Protein of unknown function (DUF2626)
HFGJIHDG_00797 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
HFGJIHDG_00799 6.5e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFGJIHDG_00800 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HFGJIHDG_00801 4.5e-185 corA P Mg2 transporter protein
HFGJIHDG_00802 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HFGJIHDG_00803 7.8e-183 comGB NU COG1459 Type II secretory pathway, component PulF
HFGJIHDG_00804 8.9e-50 comGC U Required for transformation and DNA binding
HFGJIHDG_00805 8.4e-70 gspH NU Tfp pilus assembly protein FimT
HFGJIHDG_00806 2.6e-20 comGE
HFGJIHDG_00807 1.3e-64 comGF U Putative Competence protein ComGF
HFGJIHDG_00808 6.1e-61 S ComG operon protein 7
HFGJIHDG_00809 2.3e-26 yqzE S YqzE-like protein
HFGJIHDG_00810 1.1e-53 yqzG S Protein of unknown function (DUF3889)
HFGJIHDG_00811 1.2e-120 yqxM
HFGJIHDG_00812 3.5e-71 sipW 3.4.21.89 U Signal peptidase
HFGJIHDG_00813 4.7e-140 tasA S Cell division protein FtsN
HFGJIHDG_00814 7.8e-55 sinR K transcriptional
HFGJIHDG_00815 5.2e-23 sinI S Anti-repressor SinI
HFGJIHDG_00816 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HFGJIHDG_00817 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HFGJIHDG_00818 3.9e-209 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HFGJIHDG_00819 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HFGJIHDG_00820 1.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HFGJIHDG_00821 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
HFGJIHDG_00822 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HFGJIHDG_00823 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HFGJIHDG_00824 2e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
HFGJIHDG_00825 5.8e-62 yqhP
HFGJIHDG_00826 8e-174 yqhQ S Protein of unknown function (DUF1385)
HFGJIHDG_00827 7e-87 yqhR S Conserved membrane protein YqhR
HFGJIHDG_00828 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HFGJIHDG_00829 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFGJIHDG_00830 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HFGJIHDG_00831 2.1e-171 spoIIIAA S stage III sporulation protein AA
HFGJIHDG_00832 1.6e-83 spoIIIAB S Stage III sporulation protein
HFGJIHDG_00833 7.6e-29 spoIIIAC S stage III sporulation protein AC
HFGJIHDG_00834 2.5e-41 spoIIIAD S Stage III sporulation protein AD
HFGJIHDG_00835 6.3e-200 spoIIIAE S stage III sporulation protein AE
HFGJIHDG_00836 2.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HFGJIHDG_00837 1.1e-116 spoIIIAG S stage III sporulation protein AG
HFGJIHDG_00838 2.5e-62 spoIIIAH S SpoIIIAH-like protein
HFGJIHDG_00839 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFGJIHDG_00840 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HFGJIHDG_00841 8.1e-67 yqhY S protein conserved in bacteria
HFGJIHDG_00842 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFGJIHDG_00843 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFGJIHDG_00844 1.8e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFGJIHDG_00845 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFGJIHDG_00846 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFGJIHDG_00847 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFGJIHDG_00848 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HFGJIHDG_00849 3.9e-78 argR K Regulates arginine biosynthesis genes
HFGJIHDG_00850 7.9e-305 recN L May be involved in recombinational repair of damaged DNA
HFGJIHDG_00851 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
HFGJIHDG_00852 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HFGJIHDG_00853 2.6e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFGJIHDG_00856 4.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HFGJIHDG_00858 1.2e-112 K Protein of unknown function (DUF1232)
HFGJIHDG_00859 7.7e-101 ytaF P Probably functions as a manganese efflux pump
HFGJIHDG_00860 2.1e-16
HFGJIHDG_00861 8.8e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HFGJIHDG_00862 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HFGJIHDG_00863 1.6e-211 mmgA 2.3.1.9 I Belongs to the thiolase family
HFGJIHDG_00864 1.1e-153 hbdA 1.1.1.157 I Dehydrogenase
HFGJIHDG_00865 5.3e-201 mmgC I acyl-CoA dehydrogenase
HFGJIHDG_00866 1.6e-202 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HFGJIHDG_00867 9.2e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HFGJIHDG_00868 4.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HFGJIHDG_00869 3.2e-34 yqzF S Protein of unknown function (DUF2627)
HFGJIHDG_00870 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HFGJIHDG_00871 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HFGJIHDG_00872 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HFGJIHDG_00873 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
HFGJIHDG_00874 2.9e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFGJIHDG_00875 2.1e-161 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFGJIHDG_00876 3e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFGJIHDG_00877 2.6e-188 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFGJIHDG_00878 2e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HFGJIHDG_00879 1e-75 yqiW S Belongs to the UPF0403 family
HFGJIHDG_00880 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
HFGJIHDG_00881 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
HFGJIHDG_00882 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HFGJIHDG_00883 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
HFGJIHDG_00884 3.1e-95 yqjB S protein conserved in bacteria
HFGJIHDG_00886 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HFGJIHDG_00887 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HFGJIHDG_00888 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HFGJIHDG_00889 1.7e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFGJIHDG_00890 2.4e-25 yqzJ
HFGJIHDG_00891 6.2e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFGJIHDG_00892 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFGJIHDG_00893 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFGJIHDG_00894 6.1e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFGJIHDG_00895 6.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HFGJIHDG_00896 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HFGJIHDG_00897 5.5e-50 S GlpM protein
HFGJIHDG_00898 1.1e-161 K LysR substrate binding domain
HFGJIHDG_00899 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
HFGJIHDG_00900 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HFGJIHDG_00903 1.7e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HFGJIHDG_00904 1.1e-127 IQ reductase
HFGJIHDG_00905 0.0 pksJ Q Polyketide synthase of type I
HFGJIHDG_00906 0.0 1.1.1.320 Q Polyketide synthase of type I
HFGJIHDG_00907 0.0 Q Polyketide synthase of type I
HFGJIHDG_00908 0.0 pksJ Q Polyketide synthase of type I
HFGJIHDG_00909 0.0 pfaA Q Polyketide synthase of type I
HFGJIHDG_00910 0.0 Q Polyketide synthase of type I
HFGJIHDG_00911 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HFGJIHDG_00912 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
HFGJIHDG_00913 1.7e-238 pksG 2.3.3.10 I synthase
HFGJIHDG_00914 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HFGJIHDG_00915 6.9e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFGJIHDG_00916 8e-174 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HFGJIHDG_00917 3.6e-140 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFGJIHDG_00918 1.6e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HFGJIHDG_00919 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HFGJIHDG_00920 5.6e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFGJIHDG_00922 1.3e-185 yueF S transporter activity
HFGJIHDG_00924 1.4e-56 S YolD-like protein
HFGJIHDG_00925 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFGJIHDG_00926 8.7e-89 yqjY K acetyltransferase
HFGJIHDG_00927 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HFGJIHDG_00928 1.2e-172 yqkA K GrpB protein
HFGJIHDG_00929 7.7e-61 yqkB S Belongs to the HesB IscA family
HFGJIHDG_00930 3.2e-39 yqkC S Protein of unknown function (DUF2552)
HFGJIHDG_00931 9e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HFGJIHDG_00933 2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HFGJIHDG_00935 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HFGJIHDG_00936 4e-220 yqxK 3.6.4.12 L DNA helicase
HFGJIHDG_00937 3e-57 ansR K Transcriptional regulator
HFGJIHDG_00938 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
HFGJIHDG_00939 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HFGJIHDG_00940 1.6e-239 mleN C Na H antiporter
HFGJIHDG_00941 3.8e-243 mleA 1.1.1.38 C malic enzyme
HFGJIHDG_00942 5.7e-22
HFGJIHDG_00943 1.5e-33 yqkK
HFGJIHDG_00945 1.2e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HFGJIHDG_00946 1.9e-80 fur P Belongs to the Fur family
HFGJIHDG_00947 3.7e-37 S Protein of unknown function (DUF4227)
HFGJIHDG_00948 2.8e-165 xerD L recombinase XerD
HFGJIHDG_00949 4.8e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFGJIHDG_00950 2.4e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HFGJIHDG_00951 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HFGJIHDG_00952 6.6e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HFGJIHDG_00953 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HFGJIHDG_00954 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFGJIHDG_00955 4.8e-111 spoVAA S Stage V sporulation protein AA
HFGJIHDG_00956 5.1e-60 spoVAB S Stage V sporulation protein AB
HFGJIHDG_00957 6e-79 spoVAC S stage V sporulation protein AC
HFGJIHDG_00958 1.2e-188 spoVAD I Stage V sporulation protein AD
HFGJIHDG_00959 5e-57 spoVAEB S stage V sporulation protein
HFGJIHDG_00960 5.2e-110 spoVAEA S stage V sporulation protein
HFGJIHDG_00961 3.2e-270 spoVAF EG Stage V sporulation protein AF
HFGJIHDG_00962 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFGJIHDG_00963 1.9e-153 ypuA S Secreted protein
HFGJIHDG_00964 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFGJIHDG_00965 9.1e-81 ccdC1 O Protein of unknown function (DUF1453)
HFGJIHDG_00966 6.5e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HFGJIHDG_00967 6.4e-49 ypuD
HFGJIHDG_00968 1.2e-208 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFGJIHDG_00969 2.2e-111 ribE 2.5.1.9 H Riboflavin synthase
HFGJIHDG_00970 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HFGJIHDG_00971 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HFGJIHDG_00972 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFGJIHDG_00973 1.7e-93 ypuF S Domain of unknown function (DUF309)
HFGJIHDG_00975 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFGJIHDG_00976 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFGJIHDG_00977 3.8e-93 ypuI S Protein of unknown function (DUF3907)
HFGJIHDG_00978 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HFGJIHDG_00979 2e-103 spmA S Spore maturation protein
HFGJIHDG_00980 1.3e-88 spmB S Spore maturation protein
HFGJIHDG_00981 1.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFGJIHDG_00982 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HFGJIHDG_00983 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HFGJIHDG_00984 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HFGJIHDG_00985 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_00986 0.0 resE 2.7.13.3 T Histidine kinase
HFGJIHDG_00987 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HFGJIHDG_00988 1.7e-191 rsiX
HFGJIHDG_00989 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFGJIHDG_00990 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFGJIHDG_00991 3.6e-41 fer C Ferredoxin
HFGJIHDG_00992 1.5e-194 ypbB 5.1.3.1 S protein conserved in bacteria
HFGJIHDG_00993 3e-270 recQ 3.6.4.12 L DNA helicase
HFGJIHDG_00994 4e-99 ypbD S metal-dependent membrane protease
HFGJIHDG_00995 1.2e-74 ypbE M Lysin motif
HFGJIHDG_00996 5.7e-85 ypbF S Protein of unknown function (DUF2663)
HFGJIHDG_00997 7.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HFGJIHDG_00998 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HFGJIHDG_00999 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HFGJIHDG_01000 5e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HFGJIHDG_01001 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
HFGJIHDG_01002 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HFGJIHDG_01003 1.5e-250 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HFGJIHDG_01004 1.8e-60 ypfA M Flagellar protein YcgR
HFGJIHDG_01005 1.4e-12 S Family of unknown function (DUF5359)
HFGJIHDG_01006 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HFGJIHDG_01007 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HFGJIHDG_01008 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFGJIHDG_01009 4.7e-08 S YpzI-like protein
HFGJIHDG_01010 2.1e-103 yphA
HFGJIHDG_01011 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HFGJIHDG_01012 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HFGJIHDG_01013 3.3e-16 yphE S Protein of unknown function (DUF2768)
HFGJIHDG_01014 3.1e-133 yphF
HFGJIHDG_01015 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HFGJIHDG_01016 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFGJIHDG_01017 2.1e-100 folE 3.5.4.16 H GTP cyclohydrolase
HFGJIHDG_01018 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HFGJIHDG_01019 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HFGJIHDG_01020 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFGJIHDG_01021 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFGJIHDG_01022 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HFGJIHDG_01023 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HFGJIHDG_01024 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HFGJIHDG_01025 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HFGJIHDG_01026 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HFGJIHDG_01027 1.2e-288 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFGJIHDG_01028 1.5e-154 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFGJIHDG_01029 1.2e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HFGJIHDG_01030 7.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HFGJIHDG_01031 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFGJIHDG_01032 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFGJIHDG_01033 1.9e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFGJIHDG_01034 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HFGJIHDG_01035 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFGJIHDG_01036 5.9e-233 S COG0457 FOG TPR repeat
HFGJIHDG_01037 2.1e-99 ypiB S Belongs to the UPF0302 family
HFGJIHDG_01038 2.7e-76 ypiF S Protein of unknown function (DUF2487)
HFGJIHDG_01039 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HFGJIHDG_01040 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HFGJIHDG_01041 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HFGJIHDG_01042 2.9e-105 ypjA S membrane
HFGJIHDG_01043 9.5e-141 ypjB S sporulation protein
HFGJIHDG_01044 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
HFGJIHDG_01045 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HFGJIHDG_01046 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HFGJIHDG_01047 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFGJIHDG_01048 1.2e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HFGJIHDG_01049 4.3e-132 bshB1 S proteins, LmbE homologs
HFGJIHDG_01050 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HFGJIHDG_01051 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFGJIHDG_01052 6.2e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFGJIHDG_01053 6.6e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HFGJIHDG_01054 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HFGJIHDG_01055 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HFGJIHDG_01056 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HFGJIHDG_01057 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HFGJIHDG_01058 1.5e-80 ypmB S protein conserved in bacteria
HFGJIHDG_01059 1.8e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HFGJIHDG_01060 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HFGJIHDG_01061 3e-130 dnaD L DNA replication protein DnaD
HFGJIHDG_01062 7.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFGJIHDG_01063 2.5e-91 ypoC
HFGJIHDG_01064 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HFGJIHDG_01065 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFGJIHDG_01066 2.6e-188 yppC S Protein of unknown function (DUF2515)
HFGJIHDG_01069 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
HFGJIHDG_01071 2.1e-49 yppG S YppG-like protein
HFGJIHDG_01072 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
HFGJIHDG_01073 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HFGJIHDG_01074 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HFGJIHDG_01075 1.6e-219 yprB L RNase_H superfamily
HFGJIHDG_01077 9.9e-33 cotD S Inner spore coat protein D
HFGJIHDG_01078 4.1e-98 ypsA S Belongs to the UPF0398 family
HFGJIHDG_01079 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFGJIHDG_01080 2.6e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HFGJIHDG_01081 6.5e-78 yqgA
HFGJIHDG_01082 6.6e-22 S YpzG-like protein
HFGJIHDG_01084 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HFGJIHDG_01085 4.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HFGJIHDG_01086 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFGJIHDG_01087 2.2e-235 pbuX F xanthine
HFGJIHDG_01089 1.9e-98 yrdC 3.5.1.19 Q Isochorismatase family
HFGJIHDG_01090 1.2e-56 ydfR S Protein of unknown function (DUF421)
HFGJIHDG_01091 3.9e-22 ydfR S Protein of unknown function (DUF421)
HFGJIHDG_01093 6e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HFGJIHDG_01094 4.5e-106 J Acetyltransferase (GNAT) domain
HFGJIHDG_01095 6.1e-202 bcsA Q Naringenin-chalcone synthase
HFGJIHDG_01096 1.1e-89 ypbQ S protein conserved in bacteria
HFGJIHDG_01097 0.0 ypbR S Dynamin family
HFGJIHDG_01098 2.2e-38 ypbS S Protein of unknown function (DUF2533)
HFGJIHDG_01100 1e-162 polA 2.7.7.7 L 5'3' exonuclease
HFGJIHDG_01102 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
HFGJIHDG_01103 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HFGJIHDG_01104 2e-123 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HFGJIHDG_01105 1.5e-28 ypeQ S Zinc-finger
HFGJIHDG_01106 6.1e-36 S Protein of unknown function (DUF2564)
HFGJIHDG_01107 1.3e-11 degR
HFGJIHDG_01108 1e-30 cspD K Cold-shock protein
HFGJIHDG_01109 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HFGJIHDG_01110 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFGJIHDG_01111 2.4e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HFGJIHDG_01112 3.1e-99 ypgQ S phosphohydrolase
HFGJIHDG_01113 1.7e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
HFGJIHDG_01114 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HFGJIHDG_01115 1.1e-74 yphP S Belongs to the UPF0403 family
HFGJIHDG_01116 3.3e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HFGJIHDG_01117 8.5e-113 ypjP S YpjP-like protein
HFGJIHDG_01118 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFGJIHDG_01119 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFGJIHDG_01120 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HFGJIHDG_01121 1.6e-109 hlyIII S protein, Hemolysin III
HFGJIHDG_01122 8.3e-174 pspF K Transcriptional regulator
HFGJIHDG_01123 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HFGJIHDG_01124 3.2e-37 ypmP S Protein of unknown function (DUF2535)
HFGJIHDG_01125 7.4e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HFGJIHDG_01126 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
HFGJIHDG_01127 6.1e-97 ypmS S protein conserved in bacteria
HFGJIHDG_01128 1.4e-66 ypoP K transcriptional
HFGJIHDG_01129 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFGJIHDG_01130 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HFGJIHDG_01131 4.2e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
HFGJIHDG_01132 2.6e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HFGJIHDG_01133 1.4e-178 cgeB S Spore maturation protein
HFGJIHDG_01134 1.6e-52 cgeA
HFGJIHDG_01135 1.2e-40 cgeC
HFGJIHDG_01136 2e-241 cgeD M maturation of the outermost layer of the spore
HFGJIHDG_01137 1.4e-144 yiiD K acetyltransferase
HFGJIHDG_01139 1.5e-20 yosT L Bacterial transcription activator, effector binding domain
HFGJIHDG_01140 3.5e-244 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFGJIHDG_01141 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFGJIHDG_01142 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HFGJIHDG_01143 9e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
HFGJIHDG_01144 9.8e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HFGJIHDG_01145 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
HFGJIHDG_01146 9.2e-46 yokU S YokU-like protein, putative antitoxin
HFGJIHDG_01147 9.1e-36 yozE S Belongs to the UPF0346 family
HFGJIHDG_01148 2.6e-24 E lactoylglutathione lyase activity
HFGJIHDG_01149 1.7e-125 yodN
HFGJIHDG_01151 6.2e-24 yozD S YozD-like protein
HFGJIHDG_01152 1.4e-102 yodM 3.6.1.27 I Acid phosphatase homologues
HFGJIHDG_01153 3.3e-55 yodL S YodL-like
HFGJIHDG_01155 1.3e-125 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HFGJIHDG_01156 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HFGJIHDG_01157 6.5e-22 yodI
HFGJIHDG_01158 7e-127 yodH Q Methyltransferase
HFGJIHDG_01159 7.9e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HFGJIHDG_01160 9.8e-132 yydK K Transcriptional regulator
HFGJIHDG_01161 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFGJIHDG_01162 1e-276 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
HFGJIHDG_01163 1.1e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFGJIHDG_01164 1.4e-19 S Protein of unknown function (DUF3311)
HFGJIHDG_01165 2.2e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HFGJIHDG_01166 5.7e-109 mhqD S Carboxylesterase
HFGJIHDG_01167 2.9e-105 yodC C nitroreductase
HFGJIHDG_01168 3e-56 yodB K transcriptional
HFGJIHDG_01169 2.3e-68 yoaQ S Evidence 4 Homologs of previously reported genes of
HFGJIHDG_01170 5.9e-67 yodA S tautomerase
HFGJIHDG_01172 7.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
HFGJIHDG_01173 3.3e-161 rarD S -transporter
HFGJIHDG_01174 4.9e-23
HFGJIHDG_01175 3.7e-60 yojF S Protein of unknown function (DUF1806)
HFGJIHDG_01176 5.6e-126 yojG S deacetylase
HFGJIHDG_01177 2.5e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFGJIHDG_01178 6.1e-236 norM V Multidrug efflux pump
HFGJIHDG_01180 8.2e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFGJIHDG_01181 5.8e-222 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HFGJIHDG_01182 5.2e-226 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HFGJIHDG_01183 1.9e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HFGJIHDG_01184 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
HFGJIHDG_01185 0.0 yojO P Von Willebrand factor
HFGJIHDG_01186 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HFGJIHDG_01187 2.1e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HFGJIHDG_01188 8.5e-139 S Metallo-beta-lactamase superfamily
HFGJIHDG_01189 2.5e-159 yocS S -transporter
HFGJIHDG_01190 1.9e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HFGJIHDG_01191 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
HFGJIHDG_01192 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HFGJIHDG_01193 9.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HFGJIHDG_01194 3.6e-31 yozC
HFGJIHDG_01196 2.4e-56 yozO S Bacterial PH domain
HFGJIHDG_01197 8.5e-37 yocN
HFGJIHDG_01198 3.8e-44 yozN
HFGJIHDG_01199 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
HFGJIHDG_01200 7.5e-09
HFGJIHDG_01201 1e-09 yocL
HFGJIHDG_01202 8.6e-55 dksA T general stress protein
HFGJIHDG_01204 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFGJIHDG_01205 0.0 recQ 3.6.4.12 L DNA helicase
HFGJIHDG_01206 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
HFGJIHDG_01208 1.6e-185 yocD 3.4.17.13 V peptidase S66
HFGJIHDG_01209 1.6e-93 yocC
HFGJIHDG_01210 5.2e-139 yocB J Protein required for attachment to host cells
HFGJIHDG_01211 3.6e-91 yozB S membrane
HFGJIHDG_01212 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HFGJIHDG_01213 8.4e-54 czrA K transcriptional
HFGJIHDG_01214 7.1e-92 yobW
HFGJIHDG_01215 7.2e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HFGJIHDG_01216 1.2e-92 yobS K Transcriptional regulator
HFGJIHDG_01217 4.3e-132 yobQ K helix_turn_helix, arabinose operon control protein
HFGJIHDG_01218 1.2e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HFGJIHDG_01219 6.4e-60 ykvN K Transcriptional regulator
HFGJIHDG_01220 1.1e-130 IQ Enoyl-(Acyl carrier protein) reductase
HFGJIHDG_01221 7.4e-43
HFGJIHDG_01222 1.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_01224 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFGJIHDG_01225 4.8e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFGJIHDG_01226 3.8e-268 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
HFGJIHDG_01227 2.4e-202 yoaB EGP Major facilitator Superfamily
HFGJIHDG_01228 1.9e-133 yoxB
HFGJIHDG_01229 1.4e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFGJIHDG_01230 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFGJIHDG_01231 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HFGJIHDG_01232 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFGJIHDG_01233 9e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFGJIHDG_01234 4.5e-150 gltC K Transcriptional regulator
HFGJIHDG_01235 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HFGJIHDG_01236 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HFGJIHDG_01238 1.1e-181 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HFGJIHDG_01239 4.1e-153 gltR1 K Transcriptional regulator
HFGJIHDG_01241 1.8e-50 ybzH K Helix-turn-helix domain
HFGJIHDG_01242 3.4e-198 ybcL EGP Major facilitator Superfamily
HFGJIHDG_01243 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HFGJIHDG_01244 1.8e-34 yoeD G Helix-turn-helix domain
HFGJIHDG_01245 3.5e-97 L Integrase
HFGJIHDG_01247 2.9e-96 yoeB S IseA DL-endopeptidase inhibitor
HFGJIHDG_01248 3.3e-245 yoeA V MATE efflux family protein
HFGJIHDG_01249 7.8e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
HFGJIHDG_01250 5.6e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HFGJIHDG_01251 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_01252 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_01253 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_01254 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_01255 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
HFGJIHDG_01256 1.6e-64 yngL S Protein of unknown function (DUF1360)
HFGJIHDG_01257 7.3e-302 yngK T Glycosyl hydrolase-like 10
HFGJIHDG_01258 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HFGJIHDG_01259 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HFGJIHDG_01260 7.9e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HFGJIHDG_01261 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HFGJIHDG_01262 3.6e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HFGJIHDG_01263 7.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HFGJIHDG_01264 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HFGJIHDG_01265 3.2e-104 yngC S SNARE associated Golgi protein
HFGJIHDG_01266 2.6e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HFGJIHDG_01267 9.6e-68 yngA S membrane
HFGJIHDG_01268 1.5e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HFGJIHDG_01269 3.6e-257 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HFGJIHDG_01270 3.1e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HFGJIHDG_01271 4.1e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HFGJIHDG_01272 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HFGJIHDG_01273 1.2e-216 bioI 1.14.14.46 C Cytochrome P450
HFGJIHDG_01274 1.2e-250 yxjC EG COG2610 H gluconate symporter and related permeases
HFGJIHDG_01275 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFGJIHDG_01276 5.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HFGJIHDG_01277 2.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HFGJIHDG_01278 7.3e-217 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HFGJIHDG_01279 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_01280 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_01281 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_01282 1.4e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HFGJIHDG_01283 2.8e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
HFGJIHDG_01284 8.4e-128 T Transcriptional regulatory protein, C terminal
HFGJIHDG_01285 2.3e-230 T PhoQ Sensor
HFGJIHDG_01286 1.5e-49 S Domain of unknown function (DUF4870)
HFGJIHDG_01287 5.4e-286 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HFGJIHDG_01288 5.7e-25 S Platelet-activating factor acetylhydrolase, isoform II
HFGJIHDG_01289 1.8e-61 S Platelet-activating factor acetylhydrolase, isoform II
HFGJIHDG_01290 7.4e-297 yndJ S YndJ-like protein
HFGJIHDG_01291 1.6e-79 yndH S Domain of unknown function (DUF4166)
HFGJIHDG_01292 5.4e-155 yndG S DoxX-like family
HFGJIHDG_01293 9.2e-218 exuT G Sugar (and other) transporter
HFGJIHDG_01294 1.7e-179 kdgR_1 K transcriptional
HFGJIHDG_01295 1.1e-145 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HFGJIHDG_01296 4.7e-131 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HFGJIHDG_01297 1e-56 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HFGJIHDG_01298 1.5e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HFGJIHDG_01299 1.4e-119 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HFGJIHDG_01300 2.6e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HFGJIHDG_01301 1.2e-245 agcS E Sodium alanine symporter
HFGJIHDG_01302 5.1e-41 ynfC
HFGJIHDG_01303 6e-13
HFGJIHDG_01304 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFGJIHDG_01305 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFGJIHDG_01306 3.3e-68 yccU S CoA-binding protein
HFGJIHDG_01307 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFGJIHDG_01308 1.1e-49 yneR S Belongs to the HesB IscA family
HFGJIHDG_01309 1.4e-52 yneQ
HFGJIHDG_01310 8.3e-75 yneP S Thioesterase-like superfamily
HFGJIHDG_01311 7.1e-18 tlp S Belongs to the Tlp family
HFGJIHDG_01313 8.2e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HFGJIHDG_01314 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HFGJIHDG_01315 7.5e-15 sspO S Belongs to the SspO family
HFGJIHDG_01316 2.3e-19 sspP S Belongs to the SspP family
HFGJIHDG_01317 1.1e-62 hspX O Spore coat protein
HFGJIHDG_01318 2.5e-74 yneK S Protein of unknown function (DUF2621)
HFGJIHDG_01319 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HFGJIHDG_01320 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HFGJIHDG_01321 1.7e-125 ccdA O cytochrome c biogenesis protein
HFGJIHDG_01322 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
HFGJIHDG_01323 2.3e-28 yneF S UPF0154 protein
HFGJIHDG_01324 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
HFGJIHDG_01325 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFGJIHDG_01326 9.8e-33 ynzC S UPF0291 protein
HFGJIHDG_01327 5e-111 yneB L resolvase
HFGJIHDG_01328 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HFGJIHDG_01329 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFGJIHDG_01330 2.1e-12 yoaW
HFGJIHDG_01331 1.2e-71 yndM S Protein of unknown function (DUF2512)
HFGJIHDG_01332 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HFGJIHDG_01333 9.1e-08
HFGJIHDG_01334 2.9e-140 yndL S Replication protein
HFGJIHDG_01335 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HFGJIHDG_01336 0.0 yobO M Pectate lyase superfamily protein
HFGJIHDG_01338 1.9e-92 yvgO
HFGJIHDG_01339 3.4e-65 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFGJIHDG_01341 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
HFGJIHDG_01342 3.9e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFGJIHDG_01343 5.6e-115 ynaE S Domain of unknown function (DUF3885)
HFGJIHDG_01344 1.6e-99 J Acetyltransferase (GNAT) domain
HFGJIHDG_01345 2.4e-144 yoaP 3.1.3.18 K YoaP-like
HFGJIHDG_01347 1e-09
HFGJIHDG_01348 3.7e-185 adhP 1.1.1.1 C alcohol dehydrogenase
HFGJIHDG_01349 4.5e-67 S DinB family
HFGJIHDG_01350 8.9e-122 K WYL domain
HFGJIHDG_01351 7e-17
HFGJIHDG_01356 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HFGJIHDG_01357 7.1e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
HFGJIHDG_01359 1e-259 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HFGJIHDG_01360 3.2e-209 xylR GK ROK family
HFGJIHDG_01361 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HFGJIHDG_01362 4.9e-249 xynT G MFS/sugar transport protein
HFGJIHDG_01363 3.3e-208 mrjp G Major royal jelly protein
HFGJIHDG_01364 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
HFGJIHDG_01365 4.3e-68 glnR K transcriptional
HFGJIHDG_01366 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HFGJIHDG_01367 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFGJIHDG_01368 1.3e-176 spoVK O stage V sporulation protein K
HFGJIHDG_01369 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HFGJIHDG_01370 7.6e-109 ymaB S MutT family
HFGJIHDG_01371 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFGJIHDG_01372 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFGJIHDG_01373 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HFGJIHDG_01374 1.8e-20 ymzA
HFGJIHDG_01375 3e-41
HFGJIHDG_01376 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HFGJIHDG_01377 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFGJIHDG_01378 3.6e-43 ymaF S YmaF family
HFGJIHDG_01380 2.6e-47 ebrA P Small Multidrug Resistance protein
HFGJIHDG_01381 2.6e-53 ebrB P Small Multidrug Resistance protein
HFGJIHDG_01382 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
HFGJIHDG_01383 8.7e-125 ymaC S Replication protein
HFGJIHDG_01385 7.5e-255 aprX O Belongs to the peptidase S8 family
HFGJIHDG_01386 4.1e-62 ymzB
HFGJIHDG_01387 3.6e-118 yoaK S Membrane
HFGJIHDG_01388 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
HFGJIHDG_01389 1.7e-229 cypA C Cytochrome P450
HFGJIHDG_01390 0.0 pks13 HQ Beta-ketoacyl synthase
HFGJIHDG_01391 0.0 dhbF IQ polyketide synthase
HFGJIHDG_01392 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HFGJIHDG_01393 0.0 Q Polyketide synthase of type I
HFGJIHDG_01394 0.0 rhiB IQ polyketide synthase
HFGJIHDG_01395 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HFGJIHDG_01396 5.9e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HFGJIHDG_01397 5.3e-242 pksG 2.3.3.10 I synthase
HFGJIHDG_01398 5.5e-34 acpK IQ Phosphopantetheine attachment site
HFGJIHDG_01399 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HFGJIHDG_01400 1.1e-183 pksD Q Acyl transferase domain
HFGJIHDG_01401 2.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HFGJIHDG_01402 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HFGJIHDG_01404 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFGJIHDG_01405 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFGJIHDG_01406 1.7e-88 cotE S Spore coat protein
HFGJIHDG_01407 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HFGJIHDG_01408 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HFGJIHDG_01409 1.3e-213 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HFGJIHDG_01410 4.5e-194 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HFGJIHDG_01411 1.2e-36 spoVS S Stage V sporulation protein S
HFGJIHDG_01412 4.9e-153 ymdB S protein conserved in bacteria
HFGJIHDG_01413 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
HFGJIHDG_01414 1.9e-193 pbpX V Beta-lactamase
HFGJIHDG_01415 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFGJIHDG_01416 2.7e-230 cinA 3.5.1.42 S Belongs to the CinA family
HFGJIHDG_01417 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFGJIHDG_01418 7.1e-124 ymfM S protein conserved in bacteria
HFGJIHDG_01419 1e-142 ymfK S Protein of unknown function (DUF3388)
HFGJIHDG_01420 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
HFGJIHDG_01421 1.2e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HFGJIHDG_01422 3.5e-241 ymfH S zinc protease
HFGJIHDG_01423 1.3e-235 ymfF S Peptidase M16
HFGJIHDG_01424 0.0 ydgH S drug exporters of the RND superfamily
HFGJIHDG_01425 4.3e-77 K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_01426 3e-227 ymfD EGP Major facilitator Superfamily
HFGJIHDG_01427 1.2e-132 ymfC K Transcriptional regulator
HFGJIHDG_01428 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HFGJIHDG_01429 6.3e-31 S YlzJ-like protein
HFGJIHDG_01430 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HFGJIHDG_01431 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFGJIHDG_01432 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFGJIHDG_01433 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HFGJIHDG_01434 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFGJIHDG_01435 6.4e-105 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HFGJIHDG_01436 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HFGJIHDG_01437 2.6e-42 ymxH S YlmC YmxH family
HFGJIHDG_01438 1.2e-233 pepR S Belongs to the peptidase M16 family
HFGJIHDG_01439 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HFGJIHDG_01440 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HFGJIHDG_01441 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFGJIHDG_01442 4.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HFGJIHDG_01443 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFGJIHDG_01444 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFGJIHDG_01445 3.9e-44 ylxP S protein conserved in bacteria
HFGJIHDG_01446 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFGJIHDG_01447 1.8e-47 ylxQ J ribosomal protein
HFGJIHDG_01448 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
HFGJIHDG_01449 5.4e-206 nusA K Participates in both transcription termination and antitermination
HFGJIHDG_01450 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
HFGJIHDG_01451 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFGJIHDG_01452 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFGJIHDG_01453 1.5e-233 rasP M zinc metalloprotease
HFGJIHDG_01454 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HFGJIHDG_01455 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HFGJIHDG_01456 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFGJIHDG_01457 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFGJIHDG_01458 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HFGJIHDG_01459 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFGJIHDG_01460 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HFGJIHDG_01461 8e-50 ylxL
HFGJIHDG_01462 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFGJIHDG_01463 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HFGJIHDG_01464 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HFGJIHDG_01465 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
HFGJIHDG_01466 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HFGJIHDG_01467 2.1e-191 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HFGJIHDG_01468 1.6e-155 flhG D Belongs to the ParA family
HFGJIHDG_01469 8.2e-191 flhF N Flagellar biosynthesis regulator FlhF
HFGJIHDG_01470 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HFGJIHDG_01471 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HFGJIHDG_01472 5.2e-131 fliR N Flagellar biosynthetic protein FliR
HFGJIHDG_01473 2e-37 fliQ N Role in flagellar biosynthesis
HFGJIHDG_01474 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
HFGJIHDG_01475 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
HFGJIHDG_01476 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HFGJIHDG_01477 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HFGJIHDG_01478 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HFGJIHDG_01479 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
HFGJIHDG_01480 5.7e-138 flgG N Flagellar basal body rod
HFGJIHDG_01481 4.1e-72 flgD N Flagellar basal body rod modification protein
HFGJIHDG_01482 1e-203 fliK N Flagellar hook-length control protein
HFGJIHDG_01483 1.3e-47 ylxF S MgtE intracellular N domain
HFGJIHDG_01484 2e-71 fliJ N Flagellar biosynthesis chaperone
HFGJIHDG_01485 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HFGJIHDG_01486 2e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HFGJIHDG_01487 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HFGJIHDG_01488 1.4e-263 fliF N The M ring may be actively involved in energy transduction
HFGJIHDG_01489 2.5e-31 fliE N Flagellar hook-basal body
HFGJIHDG_01490 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
HFGJIHDG_01491 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HFGJIHDG_01492 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HFGJIHDG_01493 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFGJIHDG_01494 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFGJIHDG_01495 7.2e-172 xerC L tyrosine recombinase XerC
HFGJIHDG_01496 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFGJIHDG_01497 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFGJIHDG_01498 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HFGJIHDG_01499 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HFGJIHDG_01500 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HFGJIHDG_01501 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HFGJIHDG_01502 7.8e-305 ylqG
HFGJIHDG_01503 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFGJIHDG_01504 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFGJIHDG_01505 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFGJIHDG_01506 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HFGJIHDG_01507 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFGJIHDG_01508 1.3e-61 ylqD S YlqD protein
HFGJIHDG_01509 1.7e-35 ylqC S Belongs to the UPF0109 family
HFGJIHDG_01510 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HFGJIHDG_01511 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFGJIHDG_01512 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFGJIHDG_01513 2.6e-138 S Phosphotransferase enzyme family
HFGJIHDG_01514 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFGJIHDG_01515 0.0 smc D Required for chromosome condensation and partitioning
HFGJIHDG_01516 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFGJIHDG_01517 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFGJIHDG_01518 4.6e-129 IQ reductase
HFGJIHDG_01519 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HFGJIHDG_01520 1.4e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFGJIHDG_01521 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HFGJIHDG_01522 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFGJIHDG_01523 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HFGJIHDG_01524 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HFGJIHDG_01525 3.2e-303 yloV S kinase related to dihydroxyacetone kinase
HFGJIHDG_01526 5.5e-59 asp S protein conserved in bacteria
HFGJIHDG_01527 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HFGJIHDG_01528 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
HFGJIHDG_01529 5.2e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HFGJIHDG_01530 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFGJIHDG_01531 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HFGJIHDG_01532 2.3e-139 stp 3.1.3.16 T phosphatase
HFGJIHDG_01533 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HFGJIHDG_01534 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFGJIHDG_01535 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFGJIHDG_01536 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFGJIHDG_01537 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFGJIHDG_01538 7.4e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFGJIHDG_01539 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFGJIHDG_01540 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HFGJIHDG_01541 1.5e-40 ylzA S Belongs to the UPF0296 family
HFGJIHDG_01542 8.5e-154 yloC S stress-induced protein
HFGJIHDG_01543 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HFGJIHDG_01544 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HFGJIHDG_01545 9.3e-78 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HFGJIHDG_01546 5.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HFGJIHDG_01547 4.5e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HFGJIHDG_01548 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HFGJIHDG_01549 7.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HFGJIHDG_01550 1.1e-176 cysP P phosphate transporter
HFGJIHDG_01551 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HFGJIHDG_01553 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFGJIHDG_01554 6.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFGJIHDG_01555 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFGJIHDG_01556 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HFGJIHDG_01557 0.0 carB 6.3.5.5 F Belongs to the CarB family
HFGJIHDG_01558 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HFGJIHDG_01559 4.7e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFGJIHDG_01560 2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HFGJIHDG_01561 3e-232 pyrP F Xanthine uracil
HFGJIHDG_01562 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFGJIHDG_01563 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFGJIHDG_01564 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFGJIHDG_01565 1.2e-61 dksA T COG1734 DnaK suppressor protein
HFGJIHDG_01566 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFGJIHDG_01567 8.9e-68 divIVA D Cell division initiation protein
HFGJIHDG_01568 1.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HFGJIHDG_01569 5.2e-41 yggT S membrane
HFGJIHDG_01570 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFGJIHDG_01571 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFGJIHDG_01572 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HFGJIHDG_01573 2.2e-38 ylmC S sporulation protein
HFGJIHDG_01574 4.7e-254 argE 3.5.1.16 E Acetylornithine deacetylase
HFGJIHDG_01575 5.5e-144 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HFGJIHDG_01576 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFGJIHDG_01577 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFGJIHDG_01578 1e-157 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HFGJIHDG_01579 0.0 bpr O COG1404 Subtilisin-like serine proteases
HFGJIHDG_01580 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFGJIHDG_01581 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFGJIHDG_01582 4.5e-130 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFGJIHDG_01583 3.7e-168 murB 1.3.1.98 M cell wall formation
HFGJIHDG_01584 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFGJIHDG_01585 2.2e-185 spoVE D Belongs to the SEDS family
HFGJIHDG_01586 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFGJIHDG_01587 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFGJIHDG_01588 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFGJIHDG_01589 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HFGJIHDG_01590 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HFGJIHDG_01591 2.9e-52 ftsL D Essential cell division protein
HFGJIHDG_01592 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFGJIHDG_01593 1.2e-77 mraZ K Belongs to the MraZ family
HFGJIHDG_01594 4.8e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HFGJIHDG_01595 1e-162 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFGJIHDG_01596 1.2e-88 ylbP K n-acetyltransferase
HFGJIHDG_01597 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HFGJIHDG_01598 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HFGJIHDG_01599 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
HFGJIHDG_01600 4.3e-228 ylbM S Belongs to the UPF0348 family
HFGJIHDG_01601 1.6e-188 ylbL T Belongs to the peptidase S16 family
HFGJIHDG_01602 4.4e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HFGJIHDG_01603 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
HFGJIHDG_01604 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFGJIHDG_01605 6e-97 rsmD 2.1.1.171 L Methyltransferase
HFGJIHDG_01607 5.5e-43 ylbG S UPF0298 protein
HFGJIHDG_01608 1.2e-71 ylbF S Belongs to the UPF0342 family
HFGJIHDG_01609 8.8e-37 ylbE S YlbE-like protein
HFGJIHDG_01610 7.9e-54 ylbD S Putative coat protein
HFGJIHDG_01611 4.6e-199 ylbC S protein with SCP PR1 domains
HFGJIHDG_01612 2.2e-73 ylbB T COG0517 FOG CBS domain
HFGJIHDG_01613 3.2e-59 ylbA S YugN-like family
HFGJIHDG_01614 2e-163 ctaG S cytochrome c oxidase
HFGJIHDG_01615 1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HFGJIHDG_01616 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HFGJIHDG_01617 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HFGJIHDG_01618 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HFGJIHDG_01619 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HFGJIHDG_01620 5.9e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HFGJIHDG_01621 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HFGJIHDG_01622 1.9e-212 ftsW D Belongs to the SEDS family
HFGJIHDG_01623 8.7e-44 ylaN S Belongs to the UPF0358 family
HFGJIHDG_01624 1.3e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
HFGJIHDG_01625 8.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HFGJIHDG_01626 3e-243 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HFGJIHDG_01627 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFGJIHDG_01628 1.4e-33 ylaI S protein conserved in bacteria
HFGJIHDG_01629 6.6e-48 ylaH S YlaH-like protein
HFGJIHDG_01630 0.0 typA T GTP-binding protein TypA
HFGJIHDG_01631 6.7e-24 S Family of unknown function (DUF5325)
HFGJIHDG_01632 1.3e-36 ylaE
HFGJIHDG_01633 2.2e-13 sigC S Putative zinc-finger
HFGJIHDG_01634 5.3e-292 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HFGJIHDG_01635 4e-83 ykzC S Acetyltransferase (GNAT) family
HFGJIHDG_01636 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HFGJIHDG_01637 6.3e-24 ykzI
HFGJIHDG_01638 1.8e-118 yktB S Belongs to the UPF0637 family
HFGJIHDG_01639 3.5e-42 yktA S Belongs to the UPF0223 family
HFGJIHDG_01640 3.2e-275 speA 4.1.1.19 E Arginine
HFGJIHDG_01641 1e-134 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HFGJIHDG_01642 1.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HFGJIHDG_01643 5.4e-251 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFGJIHDG_01644 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFGJIHDG_01645 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFGJIHDG_01646 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFGJIHDG_01647 3.3e-208 V Beta-lactamase
HFGJIHDG_01648 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HFGJIHDG_01649 0.0 Q Polyketide synthase of type I
HFGJIHDG_01650 0.0 Q Polyketide synthase of type I
HFGJIHDG_01651 0.0 Q Polyketide synthase of type I
HFGJIHDG_01652 0.0 Q Polyketide synthase of type I
HFGJIHDG_01653 0.0 Q polyketide synthase
HFGJIHDG_01654 0.0 Q Polyketide synthase of type I
HFGJIHDG_01655 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HFGJIHDG_01656 4.2e-102 recN L Putative cell-wall binding lipoprotein
HFGJIHDG_01658 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFGJIHDG_01659 7.4e-146 ykrA S hydrolases of the HAD superfamily
HFGJIHDG_01660 8.2e-31 ykzG S Belongs to the UPF0356 family
HFGJIHDG_01661 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFGJIHDG_01662 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HFGJIHDG_01663 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HFGJIHDG_01664 1e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HFGJIHDG_01665 1.3e-243 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HFGJIHDG_01666 2.1e-45 abrB K of stationary sporulation gene expression
HFGJIHDG_01667 6.9e-184 mreB D Rod-share determining protein MreBH
HFGJIHDG_01668 5.5e-12 S Uncharacterized protein YkpC
HFGJIHDG_01669 1.6e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HFGJIHDG_01670 3.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFGJIHDG_01671 4.2e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFGJIHDG_01672 1.7e-36 ykoA
HFGJIHDG_01673 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HFGJIHDG_01674 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HFGJIHDG_01675 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HFGJIHDG_01676 1.7e-131 fruR K Transcriptional regulator
HFGJIHDG_01677 3e-210 yknZ V ABC transporter (permease)
HFGJIHDG_01678 2e-121 macB V ABC transporter, ATP-binding protein
HFGJIHDG_01679 1.7e-167 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFGJIHDG_01680 3.4e-105 yknW S Yip1 domain
HFGJIHDG_01681 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HFGJIHDG_01682 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HFGJIHDG_01683 4.2e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HFGJIHDG_01684 1.4e-242 moeA 2.10.1.1 H molybdopterin
HFGJIHDG_01685 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HFGJIHDG_01686 1.8e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HFGJIHDG_01687 1.8e-160 yknT
HFGJIHDG_01688 4.5e-98 rok K Repressor of ComK
HFGJIHDG_01689 2.2e-76 ykuV CO thiol-disulfide
HFGJIHDG_01690 3.7e-140 ykuT M Mechanosensitive ion channel
HFGJIHDG_01691 4.8e-38 ykuS S Belongs to the UPF0180 family
HFGJIHDG_01692 9.9e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFGJIHDG_01693 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFGJIHDG_01694 6e-79 fld C Flavodoxin
HFGJIHDG_01695 2.2e-165 ykuO
HFGJIHDG_01696 1.3e-89 fld C Flavodoxin
HFGJIHDG_01697 1.3e-167 ccpC K Transcriptional regulator
HFGJIHDG_01698 1e-75 ykuL S CBS domain
HFGJIHDG_01699 2.1e-25 ykzF S Antirepressor AbbA
HFGJIHDG_01700 1.4e-92 ykuK S Ribonuclease H-like
HFGJIHDG_01701 3.9e-37 ykuJ S protein conserved in bacteria
HFGJIHDG_01702 3.3e-233 ykuI T Diguanylate phosphodiesterase
HFGJIHDG_01704 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_01705 3.1e-153 ykuE S Metallophosphoesterase
HFGJIHDG_01706 4.1e-89 ykuD S protein conserved in bacteria
HFGJIHDG_01707 2.5e-239 ykuC EGP Major facilitator Superfamily
HFGJIHDG_01708 1.4e-83 ykyB S YkyB-like protein
HFGJIHDG_01709 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
HFGJIHDG_01710 2.3e-09
HFGJIHDG_01711 3.9e-215 patA 2.6.1.1 E Aminotransferase
HFGJIHDG_01712 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
HFGJIHDG_01713 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HFGJIHDG_01714 8.3e-113 ykwD J protein with SCP PR1 domains
HFGJIHDG_01715 2.8e-64
HFGJIHDG_01716 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HFGJIHDG_01717 6.5e-263 mcpC NT chemotaxis protein
HFGJIHDG_01718 2.4e-192 splB 4.1.99.14 L Spore photoproduct lyase
HFGJIHDG_01719 6.1e-38 splA S Transcriptional regulator
HFGJIHDG_01720 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFGJIHDG_01721 2.1e-39 ptsH G phosphocarrier protein HPr
HFGJIHDG_01722 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFGJIHDG_01723 5.1e-156 glcT K antiterminator
HFGJIHDG_01724 3.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
HFGJIHDG_01726 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HFGJIHDG_01727 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HFGJIHDG_01728 1.7e-87 stoA CO thiol-disulfide
HFGJIHDG_01729 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFGJIHDG_01730 9.1e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
HFGJIHDG_01731 3.9e-27
HFGJIHDG_01732 7.8e-25 ykvS S protein conserved in bacteria
HFGJIHDG_01733 2.9e-44 ykvR S Protein of unknown function (DUF3219)
HFGJIHDG_01734 3.8e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HFGJIHDG_01735 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HFGJIHDG_01736 3.8e-78 queD 4.1.2.50, 4.2.3.12 H synthase
HFGJIHDG_01737 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HFGJIHDG_01738 2.9e-183
HFGJIHDG_01739 5.1e-182 ykvI S membrane
HFGJIHDG_01740 0.0 clpE O Belongs to the ClpA ClpB family
HFGJIHDG_01741 3.3e-136 motA N flagellar motor
HFGJIHDG_01742 2.7e-127 motB N Flagellar motor protein
HFGJIHDG_01743 5.5e-77 ykvE K transcriptional
HFGJIHDG_01744 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HFGJIHDG_01745 3.4e-10 S Spo0E like sporulation regulatory protein
HFGJIHDG_01746 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HFGJIHDG_01747 4.4e-112 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HFGJIHDG_01748 4.2e-129 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HFGJIHDG_01749 1.3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HFGJIHDG_01750 2e-227 mtnE 2.6.1.83 E Aminotransferase
HFGJIHDG_01751 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HFGJIHDG_01752 2.1e-224 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HFGJIHDG_01753 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HFGJIHDG_01755 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFGJIHDG_01756 0.0 kinE 2.7.13.3 T Histidine kinase
HFGJIHDG_01757 8e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HFGJIHDG_01758 8.7e-23 ykzE
HFGJIHDG_01759 7.2e-113 ydfR S Protein of unknown function (DUF421)
HFGJIHDG_01760 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
HFGJIHDG_01761 4.5e-155 htpX O Belongs to the peptidase M48B family
HFGJIHDG_01762 8.6e-125 ykrK S Domain of unknown function (DUF1836)
HFGJIHDG_01763 2.5e-26 sspD S small acid-soluble spore protein
HFGJIHDG_01764 1.5e-118 rsgI S Anti-sigma factor N-terminus
HFGJIHDG_01765 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFGJIHDG_01766 3.3e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HFGJIHDG_01767 3.8e-99 ykoX S membrane-associated protein
HFGJIHDG_01768 7.9e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HFGJIHDG_01769 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HFGJIHDG_01770 3.7e-99 ykoP G polysaccharide deacetylase
HFGJIHDG_01771 1.1e-80 ykoM K transcriptional
HFGJIHDG_01772 1.2e-25 ykoL
HFGJIHDG_01773 1.9e-16
HFGJIHDG_01774 5.4e-53 tnrA K transcriptional
HFGJIHDG_01775 3.2e-237 mgtE P Acts as a magnesium transporter
HFGJIHDG_01777 7.4e-244 ydhD M Glycosyl hydrolase
HFGJIHDG_01778 3.8e-97 ykoE S ABC-type cobalt transport system, permease component
HFGJIHDG_01779 5.3e-303 P ABC transporter, ATP-binding protein
HFGJIHDG_01780 2.1e-132 ykoC P Cobalt transport protein
HFGJIHDG_01781 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFGJIHDG_01782 5e-176 isp O Belongs to the peptidase S8 family
HFGJIHDG_01783 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFGJIHDG_01784 8.9e-122 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HFGJIHDG_01785 3e-215 hcaT 1.5.1.2 EGP Major facilitator Superfamily
HFGJIHDG_01786 8.2e-120 M PFAM Collagen triple helix repeat (20 copies)
HFGJIHDG_01787 1.1e-214 M Glycosyl transferase family 2
HFGJIHDG_01789 4.1e-48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFGJIHDG_01790 4.2e-71 ohrB O Organic hydroperoxide resistance protein
HFGJIHDG_01791 1.8e-72 ohrR K COG1846 Transcriptional regulators
HFGJIHDG_01792 4.1e-69 ohrA O Organic hydroperoxide resistance protein
HFGJIHDG_01793 2.2e-224 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFGJIHDG_01794 6.6e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFGJIHDG_01795 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HFGJIHDG_01796 1e-48 ykkD P Multidrug resistance protein
HFGJIHDG_01797 1.4e-51 ykkC P Multidrug resistance protein
HFGJIHDG_01798 1.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFGJIHDG_01799 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HFGJIHDG_01800 1.5e-158 ykgA E Amidinotransferase
HFGJIHDG_01801 1.3e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
HFGJIHDG_01802 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
HFGJIHDG_01803 1.1e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HFGJIHDG_01804 3.1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HFGJIHDG_01805 7.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HFGJIHDG_01806 0.0 dppE E ABC transporter substrate-binding protein
HFGJIHDG_01807 5.9e-191 dppD P Belongs to the ABC transporter superfamily
HFGJIHDG_01808 2.5e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFGJIHDG_01809 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFGJIHDG_01810 1.9e-155 dppA E D-aminopeptidase
HFGJIHDG_01811 3.7e-277 yubD P Major Facilitator Superfamily
HFGJIHDG_01812 5.6e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFGJIHDG_01814 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HFGJIHDG_01815 4.2e-300 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFGJIHDG_01816 8.2e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HFGJIHDG_01817 1.1e-242 steT E amino acid
HFGJIHDG_01818 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HFGJIHDG_01819 5.8e-175 pit P phosphate transporter
HFGJIHDG_01820 5.9e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HFGJIHDG_01821 8.7e-23 spoIISB S Stage II sporulation protein SB
HFGJIHDG_01822 5.4e-169 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HFGJIHDG_01823 1.3e-38 xhlB S SPP1 phage holin
HFGJIHDG_01824 8.7e-38 xhlA S Haemolysin XhlA
HFGJIHDG_01825 5.3e-136 xepA
HFGJIHDG_01826 1.6e-28 xkdX
HFGJIHDG_01828 1.7e-91
HFGJIHDG_01829 3.6e-26
HFGJIHDG_01830 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HFGJIHDG_01831 1.5e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HFGJIHDG_01832 4.2e-58 xkdS S Protein of unknown function (DUF2634)
HFGJIHDG_01833 2.5e-32 xkdR S Protein of unknown function (DUF2577)
HFGJIHDG_01834 4.6e-161 xkdQ 3.2.1.96 G NLP P60 protein
HFGJIHDG_01835 6.6e-111 xkdP S Lysin motif
HFGJIHDG_01836 3.4e-199 xkdO L Transglycosylase SLT domain
HFGJIHDG_01837 3.4e-19
HFGJIHDG_01838 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
HFGJIHDG_01839 2e-74 xkdM S Phage tail tube protein
HFGJIHDG_01840 3.5e-226 xkdK S Phage tail sheath C-terminal domain
HFGJIHDG_01841 8.2e-15
HFGJIHDG_01842 3.2e-56 xkdJ
HFGJIHDG_01843 5.3e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
HFGJIHDG_01844 5.5e-43 yqbH S Domain of unknown function (DUF3599)
HFGJIHDG_01845 4.3e-46 yqbG S Protein of unknown function (DUF3199)
HFGJIHDG_01846 1e-157 xkdG S Phage capsid family
HFGJIHDG_01847 1.3e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
HFGJIHDG_01848 3e-241 yqbA S portal protein
HFGJIHDG_01849 1.4e-210 xtmB S phage terminase, large subunit
HFGJIHDG_01850 3e-110 xtmA L phage terminase small subunit
HFGJIHDG_01851 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HFGJIHDG_01852 2e-10 yqaO S Phage-like element PBSX protein XtrA
HFGJIHDG_01855 5.2e-150 xkdC L Bacterial dnaA protein
HFGJIHDG_01857 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
HFGJIHDG_01858 2.9e-110 xkdA E IrrE N-terminal-like domain
HFGJIHDG_01860 6.7e-110 yjqB S phage-related replication protein
HFGJIHDG_01861 8e-61 yjqA S Bacterial PH domain
HFGJIHDG_01862 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HFGJIHDG_01864 1.9e-214 S response regulator aspartate phosphatase
HFGJIHDG_01865 3.1e-78 yjoA S DinB family
HFGJIHDG_01866 1.9e-130 MA20_18170 S membrane transporter protein
HFGJIHDG_01867 3.4e-204 salB V Domain of unknown function (DUF4135)
HFGJIHDG_01870 3.7e-219 lanT 3.6.3.27 V Peptidase C39 family
HFGJIHDG_01871 4.8e-300 lcnDR2 V Lanthionine synthetase C-like protein
HFGJIHDG_01873 5.4e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFGJIHDG_01874 3.7e-46 narQ 2.7.13.3 T Histidine kinase
HFGJIHDG_01876 2.7e-65 S ABC-2 family transporter protein
HFGJIHDG_01877 3.8e-104 V ABC transporter, ATP-binding protein
HFGJIHDG_01878 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HFGJIHDG_01879 4e-87 T Transcriptional regulatory protein, C terminal
HFGJIHDG_01880 1.3e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HFGJIHDG_01881 1.9e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HFGJIHDG_01882 7e-181 exuR K transcriptional
HFGJIHDG_01883 3.3e-253 yjmB G symporter YjmB
HFGJIHDG_01884 4e-275 uxaC 5.3.1.12 G glucuronate isomerase
HFGJIHDG_01885 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HFGJIHDG_01886 7e-66 yjlC S Protein of unknown function (DUF1641)
HFGJIHDG_01887 5.7e-91 yjlB S Cupin domain
HFGJIHDG_01888 4.4e-175 yjlA EG Putative multidrug resistance efflux transporter
HFGJIHDG_01889 1.6e-129 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
HFGJIHDG_01890 2.1e-124 ybbM S transport system, permease component
HFGJIHDG_01891 4.7e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HFGJIHDG_01892 6.8e-29
HFGJIHDG_01893 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HFGJIHDG_01894 4.8e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HFGJIHDG_01895 4.3e-92 yjgD S Protein of unknown function (DUF1641)
HFGJIHDG_01896 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HFGJIHDG_01897 5.9e-100 yjgB S Domain of unknown function (DUF4309)
HFGJIHDG_01898 2.6e-65 T PhoQ Sensor
HFGJIHDG_01899 7.5e-22 yjfB S Putative motility protein
HFGJIHDG_01901 8.1e-106 yhiD S MgtC SapB transporter
HFGJIHDG_01902 2.9e-51 K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_01903 2e-34
HFGJIHDG_01904 2.1e-123 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HFGJIHDG_01905 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
HFGJIHDG_01906 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HFGJIHDG_01907 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
HFGJIHDG_01908 2.9e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFGJIHDG_01909 4.3e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFGJIHDG_01910 1.8e-184 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFGJIHDG_01911 9.9e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HFGJIHDG_01912 3.8e-220 ganA 3.2.1.89 G arabinogalactan
HFGJIHDG_01913 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_01914 3.5e-250 yfjF EGP Belongs to the major facilitator superfamily
HFGJIHDG_01915 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
HFGJIHDG_01916 1.3e-160 bla 3.5.2.6 V beta-lactamase
HFGJIHDG_01917 8.5e-58 E Glyoxalase-like domain
HFGJIHDG_01920 4.9e-305 yobL S Bacterial EndoU nuclease
HFGJIHDG_01921 2.6e-21
HFGJIHDG_01925 2.4e-62
HFGJIHDG_01927 5.7e-119 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HFGJIHDG_01928 9e-61 S Pfam:Phage_holin_4_1
HFGJIHDG_01933 4.2e-225 S peptidoglycan catabolic process
HFGJIHDG_01934 7.3e-45
HFGJIHDG_01935 2e-124
HFGJIHDG_01937 1.9e-25 S Phage tail assembly chaperone protein, TAC
HFGJIHDG_01938 4.3e-33 S Phage tail tube protein
HFGJIHDG_01939 7.7e-30 S Protein of unknown function (DUF3168)
HFGJIHDG_01940 3.6e-38 S Bacteriophage HK97-gp10, putative tail-component
HFGJIHDG_01941 3.6e-28 S Phage head-tail joining protein
HFGJIHDG_01942 6e-27 S Phage gp6-like head-tail connector protein
HFGJIHDG_01945 2e-145 S Phage capsid family
HFGJIHDG_01946 4e-59 S Domain of unknown function (DUF4355)
HFGJIHDG_01947 4.3e-92 S Phage Mu protein F like protein
HFGJIHDG_01948 7.8e-202 S Phage portal protein, SPP1 Gp6-like
HFGJIHDG_01949 2.5e-180 ps334 S Terminase-like family
HFGJIHDG_01950 4.5e-79 yqaS L DNA packaging
HFGJIHDG_01952 8.5e-66 O Papain family cysteine protease
HFGJIHDG_01953 7.9e-13 K Transcriptional regulator
HFGJIHDG_01955 5.4e-68 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HFGJIHDG_01958 1.2e-125 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HFGJIHDG_01961 5e-17 yqaO S Phage-like element PBSX protein XtrA
HFGJIHDG_01963 5.9e-60 rusA L Endodeoxyribonuclease RusA
HFGJIHDG_01965 5.5e-122 xkdC L IstB-like ATP binding protein
HFGJIHDG_01966 1.4e-74 3.1.3.16 L DnaD domain protein
HFGJIHDG_01968 1.3e-68 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HFGJIHDG_01969 4.3e-100
HFGJIHDG_01974 3.2e-85
HFGJIHDG_01975 6.3e-46 S Phage regulatory protein Rha (Phage_pRha)
HFGJIHDG_01976 3.4e-15 S Helix-turn-helix domain
HFGJIHDG_01977 4.2e-17 K Helix-turn-helix domain
HFGJIHDG_01978 3.7e-18 xre K Helix-turn-helix XRE-family like proteins
HFGJIHDG_01979 5.7e-26 S Short C-terminal domain
HFGJIHDG_01980 1.3e-48 xkdA E IrrE N-terminal-like domain
HFGJIHDG_01981 8.4e-176 L Belongs to the 'phage' integrase family
HFGJIHDG_01983 2.2e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HFGJIHDG_01984 4.3e-211 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HFGJIHDG_01985 3e-125 yjcH P COG2382 Enterochelin esterase and related enzymes
HFGJIHDG_01986 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HFGJIHDG_01987 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFGJIHDG_01988 2.7e-35 K SpoVT / AbrB like domain
HFGJIHDG_01989 6.4e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HFGJIHDG_01990 5.7e-124 S ABC-2 type transporter
HFGJIHDG_01991 2.2e-139 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HFGJIHDG_01992 1.3e-35
HFGJIHDG_01993 0.0 yjcD 3.6.4.12 L DNA helicase
HFGJIHDG_01994 3.8e-38 spoVIF S Stage VI sporulation protein F
HFGJIHDG_01998 5.6e-56 yjcA S Protein of unknown function (DUF1360)
HFGJIHDG_01999 1.4e-52 cotV S Spore Coat Protein X and V domain
HFGJIHDG_02000 6.8e-21 cotW
HFGJIHDG_02001 5.1e-71 cotX S Spore Coat Protein X and V domain
HFGJIHDG_02002 4.6e-93 cotY S Spore coat protein Z
HFGJIHDG_02003 6.7e-83 cotZ S Spore coat protein
HFGJIHDG_02004 2.1e-84 yjbX S Spore coat protein
HFGJIHDG_02005 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HFGJIHDG_02006 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFGJIHDG_02007 2.1e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HFGJIHDG_02008 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HFGJIHDG_02009 6.7e-30 thiS H Thiamine biosynthesis
HFGJIHDG_02010 8e-210 thiO 1.4.3.19 E Glycine oxidase
HFGJIHDG_02011 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HFGJIHDG_02012 6.4e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFGJIHDG_02013 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFGJIHDG_02014 2.6e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HFGJIHDG_02015 3.7e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFGJIHDG_02016 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFGJIHDG_02017 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
HFGJIHDG_02018 3.9e-60 yjbL S Belongs to the UPF0738 family
HFGJIHDG_02019 4e-96 yjbK S protein conserved in bacteria
HFGJIHDG_02020 1.2e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HFGJIHDG_02021 4.8e-72 yjbI S Bacterial-like globin
HFGJIHDG_02022 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HFGJIHDG_02023 5.8e-19
HFGJIHDG_02024 0.0 pepF E oligoendopeptidase F
HFGJIHDG_02025 1.4e-217 yjbF S Competence protein
HFGJIHDG_02026 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HFGJIHDG_02027 4.7e-109 yjbE P Integral membrane protein TerC family
HFGJIHDG_02028 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFGJIHDG_02029 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFGJIHDG_02030 9.8e-230 S Putative glycosyl hydrolase domain
HFGJIHDG_02031 2.3e-170 oppF E Belongs to the ABC transporter superfamily
HFGJIHDG_02032 2.7e-202 oppD P Belongs to the ABC transporter superfamily
HFGJIHDG_02033 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFGJIHDG_02034 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFGJIHDG_02035 0.0 oppA E ABC transporter substrate-binding protein
HFGJIHDG_02036 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HFGJIHDG_02037 1.2e-145 yjbA S Belongs to the UPF0736 family
HFGJIHDG_02038 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFGJIHDG_02039 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFGJIHDG_02040 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HFGJIHDG_02041 5.9e-188 appF E Belongs to the ABC transporter superfamily
HFGJIHDG_02042 1.7e-182 appD P Belongs to the ABC transporter superfamily
HFGJIHDG_02043 5.6e-149 yjaZ O Zn-dependent protease
HFGJIHDG_02044 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFGJIHDG_02045 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFGJIHDG_02046 1e-31 yjzB
HFGJIHDG_02047 1.1e-26 comZ S ComZ
HFGJIHDG_02048 2.7e-165 med S Transcriptional activator protein med
HFGJIHDG_02049 8.8e-104 yjaV
HFGJIHDG_02050 4.6e-137 yjaU I carboxylic ester hydrolase activity
HFGJIHDG_02051 3.3e-23 yjzD S Protein of unknown function (DUF2929)
HFGJIHDG_02052 1.2e-27 yjzC S YjzC-like protein
HFGJIHDG_02053 7.8e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFGJIHDG_02054 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HFGJIHDG_02055 1.3e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HFGJIHDG_02056 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HFGJIHDG_02057 1.6e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HFGJIHDG_02058 6.1e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFGJIHDG_02059 5.6e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HFGJIHDG_02060 1.2e-89 norB G Major Facilitator Superfamily
HFGJIHDG_02061 1.5e-272 yitY C D-arabinono-1,4-lactone oxidase
HFGJIHDG_02062 4.6e-73 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HFGJIHDG_02063 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HFGJIHDG_02064 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HFGJIHDG_02065 4.3e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HFGJIHDG_02066 3.5e-07
HFGJIHDG_02067 4.4e-26 S Protein of unknown function (DUF3813)
HFGJIHDG_02068 5.5e-80 ipi S Intracellular proteinase inhibitor
HFGJIHDG_02069 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HFGJIHDG_02070 4.6e-157 yitS S protein conserved in bacteria
HFGJIHDG_02072 1.7e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HFGJIHDG_02073 2.2e-171 yufN S ABC transporter substrate-binding protein PnrA-like
HFGJIHDG_02074 7.6e-160 cvfB S protein conserved in bacteria
HFGJIHDG_02075 6.6e-55 yajQ S Belongs to the UPF0234 family
HFGJIHDG_02076 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HFGJIHDG_02077 2.4e-80 yjcF S Acetyltransferase (GNAT) domain
HFGJIHDG_02078 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
HFGJIHDG_02079 9.8e-83 yisT S DinB family
HFGJIHDG_02080 7.6e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HFGJIHDG_02081 4.1e-144 purR K helix_turn _helix lactose operon repressor
HFGJIHDG_02082 2.3e-159 yisR K Transcriptional regulator
HFGJIHDG_02083 1.5e-245 yisQ V Mate efflux family protein
HFGJIHDG_02084 2.2e-131 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HFGJIHDG_02085 0.0 asnO 6.3.5.4 E Asparagine synthase
HFGJIHDG_02086 7.6e-97 yisN S Protein of unknown function (DUF2777)
HFGJIHDG_02087 3.2e-59 yisL S UPF0344 protein
HFGJIHDG_02088 5.1e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HFGJIHDG_02089 4.8e-07 yisI S Spo0E like sporulation regulatory protein
HFGJIHDG_02090 8.4e-34 gerPA S Spore germination protein
HFGJIHDG_02091 1.8e-34 gerPB S cell differentiation
HFGJIHDG_02092 1.4e-62 gerPC S Spore germination protein
HFGJIHDG_02093 3.1e-23 gerPD S Spore germination protein
HFGJIHDG_02094 1.1e-63 gerPE S Spore germination protein GerPE
HFGJIHDG_02095 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
HFGJIHDG_02096 5e-50 yisB V COG1403 Restriction endonuclease
HFGJIHDG_02097 0.0 sbcC L COG0419 ATPase involved in DNA repair
HFGJIHDG_02098 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFGJIHDG_02099 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HFGJIHDG_02100 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HFGJIHDG_02101 2.5e-119 ydfS S Protein of unknown function (DUF421)
HFGJIHDG_02102 6.3e-93 yhjR S Rubrerythrin
HFGJIHDG_02103 1.1e-107 K QacR-like protein, C-terminal region
HFGJIHDG_02104 3e-202 blt EGP Major facilitator Superfamily
HFGJIHDG_02105 1.8e-188 abrB S membrane
HFGJIHDG_02106 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_02107 1.6e-269 yhjG CH FAD binding domain
HFGJIHDG_02109 6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HFGJIHDG_02110 2.6e-109 yhjE S SNARE associated Golgi protein
HFGJIHDG_02111 1.7e-60 yhjD
HFGJIHDG_02112 3.1e-27 yhjC S Protein of unknown function (DUF3311)
HFGJIHDG_02113 3.8e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFGJIHDG_02114 3.3e-47 S Belongs to the UPF0145 family
HFGJIHDG_02115 1.6e-42 yhjA S Excalibur calcium-binding domain
HFGJIHDG_02116 8.7e-125 yrpD S Domain of unknown function, YrpD
HFGJIHDG_02117 3.5e-61 frataxin S Domain of unknown function (DU1801)
HFGJIHDG_02118 4.7e-66 frataxin S Domain of unknown function (DU1801)
HFGJIHDG_02119 1.9e-109 comK K Competence transcription factor
HFGJIHDG_02120 5.4e-31 yhzC S IDEAL
HFGJIHDG_02121 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_02122 1.3e-295 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HFGJIHDG_02123 1.5e-196 hemAT NT chemotaxis protein
HFGJIHDG_02124 3.5e-89 bioY S BioY family
HFGJIHDG_02125 3.6e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HFGJIHDG_02126 6.7e-201 vraB 2.3.1.9 I Belongs to the thiolase family
HFGJIHDG_02127 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HFGJIHDG_02128 1.6e-149 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HFGJIHDG_02129 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HFGJIHDG_02130 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
HFGJIHDG_02131 1.3e-64 yhfM
HFGJIHDG_02132 2.7e-296 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HFGJIHDG_02133 7.9e-109 yhfK GM NmrA-like family
HFGJIHDG_02134 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
HFGJIHDG_02135 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HFGJIHDG_02136 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFGJIHDG_02137 1.7e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HFGJIHDG_02139 3.7e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFGJIHDG_02140 7.2e-245 yhgE S YhgE Pip N-terminal domain protein
HFGJIHDG_02141 3.2e-101 yhgD K Transcriptional regulator
HFGJIHDG_02143 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HFGJIHDG_02144 9.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HFGJIHDG_02145 3.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HFGJIHDG_02146 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HFGJIHDG_02147 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HFGJIHDG_02148 6.2e-244 yhfA C membrane
HFGJIHDG_02149 7.5e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HFGJIHDG_02150 4e-122 ecsC S EcsC protein family
HFGJIHDG_02151 1.5e-220 ecsB U ABC transporter
HFGJIHDG_02152 1.1e-135 ecsA V transporter (ATP-binding protein)
HFGJIHDG_02153 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HFGJIHDG_02154 2.3e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFGJIHDG_02155 1.4e-76 trpP S Tryptophan transporter TrpP
HFGJIHDG_02156 2e-17
HFGJIHDG_02157 6.2e-39 yhaH S YtxH-like protein
HFGJIHDG_02158 8.6e-113 hpr K Negative regulator of protease production and sporulation
HFGJIHDG_02159 1.7e-54 yhaI S Protein of unknown function (DUF1878)
HFGJIHDG_02160 7e-95 yhaK S Putative zincin peptidase
HFGJIHDG_02161 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFGJIHDG_02162 1.8e-31 yhaL S Sporulation protein YhaL
HFGJIHDG_02163 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HFGJIHDG_02164 0.0 yhaN L AAA domain
HFGJIHDG_02165 7.2e-236 yhaO L DNA repair exonuclease
HFGJIHDG_02166 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HFGJIHDG_02167 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
HFGJIHDG_02168 2.8e-14 S YhzD-like protein
HFGJIHDG_02169 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
HFGJIHDG_02171 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HFGJIHDG_02172 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HFGJIHDG_02173 4.6e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HFGJIHDG_02174 3.3e-291 hemZ H coproporphyrinogen III oxidase
HFGJIHDG_02175 2.8e-157 yhaX S haloacid dehalogenase-like hydrolase
HFGJIHDG_02176 3.5e-200 yhaZ L DNA alkylation repair enzyme
HFGJIHDG_02177 4.4e-53 yheA S Belongs to the UPF0342 family
HFGJIHDG_02178 1e-204 yheB S Belongs to the UPF0754 family
HFGJIHDG_02179 3.4e-213 yheC HJ YheC/D like ATP-grasp
HFGJIHDG_02180 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HFGJIHDG_02181 1.7e-36 yheE S Family of unknown function (DUF5342)
HFGJIHDG_02182 1.3e-28 sspB S spore protein
HFGJIHDG_02184 1.6e-111 yheG GM NAD(P)H-binding
HFGJIHDG_02185 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HFGJIHDG_02186 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HFGJIHDG_02188 6.2e-85 T universal stress protein
HFGJIHDG_02189 1.8e-93 ymcC S Membrane
HFGJIHDG_02190 3e-87 pksA K Transcriptional regulator
HFGJIHDG_02191 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HFGJIHDG_02192 1.1e-155 yheN G deacetylase
HFGJIHDG_02193 2.9e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HFGJIHDG_02194 3.5e-205 yhdY M Mechanosensitive ion channel
HFGJIHDG_02196 7.2e-127 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HFGJIHDG_02197 1.9e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFGJIHDG_02198 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFGJIHDG_02199 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HFGJIHDG_02200 1.6e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFGJIHDG_02201 3.6e-224 yhdR 2.6.1.1 E Aminotransferase
HFGJIHDG_02202 2.8e-70 cueR K transcriptional
HFGJIHDG_02203 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HFGJIHDG_02204 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HFGJIHDG_02205 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HFGJIHDG_02206 1.3e-201 yhdL S Sigma factor regulator N-terminal
HFGJIHDG_02207 8.1e-45 yhdK S Sigma-M inhibitor protein
HFGJIHDG_02208 2.9e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HFGJIHDG_02209 1.2e-250 yhdG E amino acid
HFGJIHDG_02210 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_02211 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HFGJIHDG_02212 1.3e-162 citR K Transcriptional regulator
HFGJIHDG_02213 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HFGJIHDG_02214 7.5e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HFGJIHDG_02215 3e-270 ycgB S Stage V sporulation protein R
HFGJIHDG_02216 3.1e-244 ygxB M Conserved TM helix
HFGJIHDG_02217 1.6e-73 nsrR K Transcriptional regulator
HFGJIHDG_02218 5.4e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HFGJIHDG_02219 1.1e-53 yhdC S Protein of unknown function (DUF3889)
HFGJIHDG_02220 2.5e-39 yhdB S YhdB-like protein
HFGJIHDG_02221 4.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
HFGJIHDG_02222 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFGJIHDG_02223 1.3e-202 yhcY 2.7.13.3 T Histidine kinase
HFGJIHDG_02224 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HFGJIHDG_02225 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HFGJIHDG_02226 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFGJIHDG_02227 3.2e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HFGJIHDG_02228 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HFGJIHDG_02229 7.8e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFGJIHDG_02230 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HFGJIHDG_02231 4.9e-125 yhcW 5.4.2.6 S hydrolase
HFGJIHDG_02232 9.9e-68 yhcV S COG0517 FOG CBS domain
HFGJIHDG_02233 1.3e-69 yhcU S Family of unknown function (DUF5365)
HFGJIHDG_02234 2.6e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFGJIHDG_02235 3.8e-75 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HFGJIHDG_02236 1.5e-14 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HFGJIHDG_02237 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
HFGJIHDG_02238 8.4e-114 yhcQ M Spore coat protein
HFGJIHDG_02239 2.2e-160 yhcP
HFGJIHDG_02240 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFGJIHDG_02241 1.9e-51 yhcM
HFGJIHDG_02242 9.7e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFGJIHDG_02243 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HFGJIHDG_02244 1.8e-142 metQ M Belongs to the nlpA lipoprotein family
HFGJIHDG_02245 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
HFGJIHDG_02246 8.2e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFGJIHDG_02247 1.3e-165 yhcH V ABC transporter, ATP-binding protein
HFGJIHDG_02248 2.8e-123 yhcG V ABC transporter, ATP-binding protein
HFGJIHDG_02249 3.6e-61 yhcF K Transcriptional regulator
HFGJIHDG_02250 4.8e-52
HFGJIHDG_02251 3.8e-55 yhcC
HFGJIHDG_02252 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
HFGJIHDG_02253 8.4e-285 yhcA EGP Major facilitator Superfamily
HFGJIHDG_02254 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
HFGJIHDG_02255 5e-73 yhbI K DNA-binding transcription factor activity
HFGJIHDG_02256 3.9e-215 yhbH S Belongs to the UPF0229 family
HFGJIHDG_02257 0.0 prkA T Ser protein kinase
HFGJIHDG_02259 5.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HFGJIHDG_02260 5.2e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HFGJIHDG_02261 2.8e-106 yhbD K Protein of unknown function (DUF4004)
HFGJIHDG_02262 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFGJIHDG_02263 1.4e-173 yhbB S Putative amidase domain
HFGJIHDG_02264 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HFGJIHDG_02265 7.2e-107 yhzB S B3/4 domain
HFGJIHDG_02267 4.8e-23 K Transcriptional regulator
HFGJIHDG_02268 3.3e-80 ygaO
HFGJIHDG_02269 2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFGJIHDG_02270 1.4e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HFGJIHDG_02271 7.5e-144 ssuC P ABC transporter (permease)
HFGJIHDG_02272 1.7e-179 ssuA M Sulfonate ABC transporter
HFGJIHDG_02273 6.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HFGJIHDG_02274 2.5e-180 S Amidohydrolase
HFGJIHDG_02275 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HFGJIHDG_02276 2.4e-133 oppF3 E Belongs to the ABC transporter superfamily
HFGJIHDG_02277 3.7e-134 oppD3 P Belongs to the ABC transporter superfamily
HFGJIHDG_02278 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFGJIHDG_02279 3.7e-147 appB P Binding-protein-dependent transport system inner membrane component
HFGJIHDG_02280 3.7e-230 oppA5 E PFAM extracellular solute-binding protein family 5
HFGJIHDG_02282 2.6e-264 ygaK C Berberine and berberine like
HFGJIHDG_02283 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HFGJIHDG_02284 1.4e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HFGJIHDG_02285 6.8e-40 C Na+/H+ antiporter family
HFGJIHDG_02289 1.6e-08
HFGJIHDG_02297 7.8e-08
HFGJIHDG_02302 1.5e-08
HFGJIHDG_02303 3.4e-39 S COG NOG14552 non supervised orthologous group
HFGJIHDG_02306 1.7e-249 iolT EGP Major facilitator Superfamily
HFGJIHDG_02307 7.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
HFGJIHDG_02308 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HFGJIHDG_02309 1.9e-163 ydhU P Catalase
HFGJIHDG_02310 9.3e-297 yveA E amino acid
HFGJIHDG_02311 2.9e-102 yvdT K Transcriptional regulator
HFGJIHDG_02312 8.6e-51 ykkC P Small Multidrug Resistance protein
HFGJIHDG_02313 7.7e-49 sugE P Small Multidrug Resistance protein
HFGJIHDG_02314 8.2e-216 yeaN P COG2807 Cyanate permease
HFGJIHDG_02315 9.9e-118 K FCD
HFGJIHDG_02316 1.5e-132 ydhQ K UTRA
HFGJIHDG_02317 2e-195 pbuE EGP Major facilitator Superfamily
HFGJIHDG_02318 5.5e-98 ydhK M Protein of unknown function (DUF1541)
HFGJIHDG_02320 8.4e-57 pbpE V Beta-lactamase
HFGJIHDG_02321 5.7e-194 pbpE V Beta-lactamase
HFGJIHDG_02324 5e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HFGJIHDG_02325 2.6e-118 ydhC K FCD
HFGJIHDG_02326 6.8e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HFGJIHDG_02327 9.7e-105 S Alpha/beta hydrolase family
HFGJIHDG_02328 8.1e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HFGJIHDG_02329 1.1e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HFGJIHDG_02330 2.2e-148 bltR K helix_turn_helix, mercury resistance
HFGJIHDG_02331 2.2e-81 bltD 2.3.1.57 K FR47-like protein
HFGJIHDG_02332 9.4e-122 ydhB S membrane transporter protein
HFGJIHDG_02333 5e-156 K Helix-turn-helix XRE-family like proteins
HFGJIHDG_02334 1.1e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFGJIHDG_02335 3.9e-210 tcaB EGP Major facilitator Superfamily
HFGJIHDG_02336 1.1e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HFGJIHDG_02337 1.2e-149 S Uncharacterized protein conserved in bacteria (DUF2179)
HFGJIHDG_02338 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
HFGJIHDG_02339 1.8e-298 expZ S ABC transporter
HFGJIHDG_02340 1.8e-133 puuD S Peptidase C26
HFGJIHDG_02341 0.0 ydfJ S drug exporters of the RND superfamily
HFGJIHDG_02342 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFGJIHDG_02343 6.2e-214 ydfH 2.7.13.3 T Histidine kinase
HFGJIHDG_02344 1.4e-34 yraG
HFGJIHDG_02345 8.4e-63 yraF M Spore coat protein
HFGJIHDG_02346 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HFGJIHDG_02347 5.4e-24 yraE
HFGJIHDG_02348 1.4e-47 yraD M Spore coat protein
HFGJIHDG_02349 1.6e-100 ydeS K Transcriptional regulator
HFGJIHDG_02350 2.6e-174 ydeR EGP Major facilitator Superfamily
HFGJIHDG_02352 3e-113 paiB K Transcriptional regulator
HFGJIHDG_02353 4.9e-257 K helix_turn_helix gluconate operon transcriptional repressor
HFGJIHDG_02354 2.3e-224 mleN_2 C antiporter
HFGJIHDG_02355 1.8e-66 yraB K helix_turn_helix, mercury resistance
HFGJIHDG_02356 4.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
HFGJIHDG_02357 4e-165 S Sodium Bile acid symporter family
HFGJIHDG_02358 4.5e-51 ydeH
HFGJIHDG_02359 3.4e-194 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HFGJIHDG_02361 7.4e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
HFGJIHDG_02362 1.8e-14 ykkA S Protein of unknown function (DUF664)
HFGJIHDG_02365 4e-195 trkA P Oxidoreductase
HFGJIHDG_02366 1.1e-167 czcD P COG1230 Co Zn Cd efflux system component
HFGJIHDG_02367 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFGJIHDG_02368 6.6e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
HFGJIHDG_02371 5.5e-28 3.6.1.55 F Belongs to the Nudix hydrolase family
HFGJIHDG_02372 3.3e-191 ydeG EGP Major facilitator superfamily
HFGJIHDG_02373 4.9e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFGJIHDG_02374 1.2e-174 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HFGJIHDG_02375 7.6e-126 rhaS5 K helix_turn_helix, arabinose operon control protein
HFGJIHDG_02376 5.3e-164 E Peptidase dimerisation domain
HFGJIHDG_02377 3.6e-24 sdaC E Serine transporter
HFGJIHDG_02378 1.3e-81 sdaC E Serine transporter
HFGJIHDG_02379 1.7e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
HFGJIHDG_02380 2.7e-67 K COG1802 Transcriptional regulators
HFGJIHDG_02381 2.5e-116 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HFGJIHDG_02382 2.1e-82 S DinB superfamily
HFGJIHDG_02383 2.6e-180 S Patatin-like phospholipase
HFGJIHDG_02384 4.1e-50 K Transcriptional regulator PadR-like family
HFGJIHDG_02385 4.1e-101 S Protein of unknown function (DUF2812)
HFGJIHDG_02386 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HFGJIHDG_02387 1.1e-117 yrkJ S membrane transporter protein
HFGJIHDG_02388 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
HFGJIHDG_02389 3.4e-200 yrkH P Rhodanese Homology Domain
HFGJIHDG_02390 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HFGJIHDG_02391 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
HFGJIHDG_02392 9.2e-40 yrkD S protein conserved in bacteria
HFGJIHDG_02393 1.4e-30 cspL K Cold shock
HFGJIHDG_02394 4.2e-110 ywnB S NAD(P)H-binding
HFGJIHDG_02395 3.1e-72 ywnA K Transcriptional regulator
HFGJIHDG_02396 3.5e-63 yyaQ S YjbR
HFGJIHDG_02397 1e-72 maoC I N-terminal half of MaoC dehydratase
HFGJIHDG_02398 5.4e-86 S Domain of unknown function with cystatin-like fold (DUF4467)
HFGJIHDG_02399 1.4e-48 ohrR K Transcriptional regulator
HFGJIHDG_02401 4.8e-46 ohrB O OsmC-like protein
HFGJIHDG_02402 3.8e-136 I esterase
HFGJIHDG_02403 9.8e-229 proP EGP Transporter
HFGJIHDG_02404 2.3e-150 S Serine aminopeptidase, S33
HFGJIHDG_02405 1.7e-201 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HFGJIHDG_02406 2.9e-49 S SMI1-KNR4 cell-wall
HFGJIHDG_02408 2.3e-79 S FRG
HFGJIHDG_02410 1.6e-25 S response regulator aspartate phosphatase
HFGJIHDG_02411 3.7e-31 S response regulator aspartate phosphatase
HFGJIHDG_02413 6.5e-55 ydcQ D Ftsk spoiiie family protein
HFGJIHDG_02421 4.3e-58 ydcK S Belongs to the SprT family
HFGJIHDG_02422 1.7e-14
HFGJIHDG_02423 0.0 yhgF K COG2183 Transcriptional accessory protein
HFGJIHDG_02424 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HFGJIHDG_02425 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFGJIHDG_02426 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HFGJIHDG_02427 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HFGJIHDG_02428 1.7e-187 rsbU 3.1.3.3 KT phosphatase
HFGJIHDG_02429 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HFGJIHDG_02430 1.8e-57 rsbS T antagonist
HFGJIHDG_02431 6.1e-146 rsbR T Positive regulator of sigma-B
HFGJIHDG_02432 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HFGJIHDG_02433 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HFGJIHDG_02434 2.2e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFGJIHDG_02435 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HFGJIHDG_02436 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFGJIHDG_02437 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HFGJIHDG_02438 4.5e-261 ydbT S Membrane
HFGJIHDG_02439 5.1e-60 ydbS S Bacterial PH domain
HFGJIHDG_02440 5.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFGJIHDG_02441 1.2e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFGJIHDG_02442 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HFGJIHDG_02443 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HFGJIHDG_02444 3.1e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFGJIHDG_02445 5.8e-09 S Fur-regulated basic protein A
HFGJIHDG_02446 1.5e-10 S Fur-regulated basic protein B
HFGJIHDG_02447 3e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HFGJIHDG_02448 4.6e-52 ydbL
HFGJIHDG_02449 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFGJIHDG_02450 6.1e-171 ydbJ V ABC transporter, ATP-binding protein
HFGJIHDG_02451 4e-158 ydbI S AI-2E family transporter
HFGJIHDG_02452 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFGJIHDG_02453 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HFGJIHDG_02454 1.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HFGJIHDG_02455 1.9e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HFGJIHDG_02456 1.2e-154 ydbD P Catalase
HFGJIHDG_02457 8.5e-60 ydbC S Domain of unknown function (DUF4937
HFGJIHDG_02458 3.4e-58 ydbB G Cupin domain
HFGJIHDG_02460 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HFGJIHDG_02461 7.8e-53 yvaE P Small Multidrug Resistance protein
HFGJIHDG_02462 1.2e-70 yvaD S Family of unknown function (DUF5360)
HFGJIHDG_02463 6.5e-34 ydaT
HFGJIHDG_02466 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
HFGJIHDG_02467 1.8e-38
HFGJIHDG_02468 8.5e-97
HFGJIHDG_02469 4.2e-74
HFGJIHDG_02471 4.2e-12
HFGJIHDG_02472 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HFGJIHDG_02473 2.2e-73 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HFGJIHDG_02474 0.0 ydaO E amino acid
HFGJIHDG_02475 0.0 ydaN S Bacterial cellulose synthase subunit
HFGJIHDG_02476 7.2e-231 ydaM M Glycosyl transferase family group 2
HFGJIHDG_02477 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HFGJIHDG_02478 4.3e-147 ydaK T Diguanylate cyclase, GGDEF domain
HFGJIHDG_02479 1.6e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HFGJIHDG_02480 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFGJIHDG_02481 4.3e-74 lrpC K Transcriptional regulator
HFGJIHDG_02482 1.3e-47 ydzA EGP Major facilitator Superfamily
HFGJIHDG_02483 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HFGJIHDG_02484 1.2e-76 ydaG 1.4.3.5 S general stress protein
HFGJIHDG_02485 3.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFGJIHDG_02486 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HFGJIHDG_02487 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_02488 5.5e-286 ydaB IQ acyl-CoA ligase
HFGJIHDG_02489 0.0 mtlR K transcriptional regulator, MtlR
HFGJIHDG_02490 3.7e-173 ydhF S Oxidoreductase
HFGJIHDG_02491 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HFGJIHDG_02492 5.1e-56 yczJ S biosynthesis
HFGJIHDG_02494 1e-116 ycsK E anatomical structure formation involved in morphogenesis
HFGJIHDG_02495 3.7e-129 kipR K Transcriptional regulator
HFGJIHDG_02496 1.2e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HFGJIHDG_02497 5.6e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HFGJIHDG_02498 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
HFGJIHDG_02499 5.7e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HFGJIHDG_02500 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
HFGJIHDG_02501 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HFGJIHDG_02503 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HFGJIHDG_02504 7.1e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HFGJIHDG_02505 5.2e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HFGJIHDG_02506 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HFGJIHDG_02507 1.6e-55
HFGJIHDG_02508 9.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HFGJIHDG_02509 2e-297 ycnJ P protein, homolog of Cu resistance protein CopC
HFGJIHDG_02510 2.3e-97 ycnI S protein conserved in bacteria
HFGJIHDG_02511 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_02512 3.6e-149 glcU U Glucose uptake
HFGJIHDG_02513 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFGJIHDG_02514 1.9e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFGJIHDG_02515 4.4e-261 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFGJIHDG_02516 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HFGJIHDG_02517 1e-44 ycnE S Monooxygenase
HFGJIHDG_02518 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
HFGJIHDG_02519 3e-151 ycnC K Transcriptional regulator
HFGJIHDG_02520 2.1e-247 ycnB EGP Major facilitator Superfamily
HFGJIHDG_02521 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HFGJIHDG_02522 4e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HFGJIHDG_02523 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_02524 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_02525 1.6e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
HFGJIHDG_02527 1.6e-80 S aspartate phosphatase
HFGJIHDG_02528 4.1e-259 T PhoQ Sensor
HFGJIHDG_02529 7.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_02530 1.4e-227 yclI V ABC transporter (permease) YclI
HFGJIHDG_02531 1.6e-120 yclH P ABC transporter
HFGJIHDG_02532 1.9e-250 yxeQ S MmgE/PrpD family
HFGJIHDG_02533 7.8e-216 yxeP 3.5.1.47 E hydrolase activity
HFGJIHDG_02534 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HFGJIHDG_02535 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
HFGJIHDG_02536 2.1e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
HFGJIHDG_02537 1.1e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFGJIHDG_02538 1.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFGJIHDG_02539 1.1e-195 gerKB F Spore germination protein
HFGJIHDG_02540 5.2e-234 gerKC S spore germination
HFGJIHDG_02541 7.8e-294 gerKA EG Spore germination protein
HFGJIHDG_02543 9.2e-277 yclG M Pectate lyase superfamily protein
HFGJIHDG_02544 1.2e-269 dtpT E amino acid peptide transporter
HFGJIHDG_02545 1.3e-76 yclD
HFGJIHDG_02546 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
HFGJIHDG_02547 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HFGJIHDG_02548 9.4e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HFGJIHDG_02549 3.9e-159 bsdA K LysR substrate binding domain
HFGJIHDG_02550 1.2e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HFGJIHDG_02551 6.3e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
HFGJIHDG_02552 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HFGJIHDG_02553 1.7e-108 yczE S membrane
HFGJIHDG_02554 1.9e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HFGJIHDG_02555 6.1e-249 bamJ E Aminotransferase class I and II
HFGJIHDG_02556 3.4e-140 srfAD Q thioesterase
HFGJIHDG_02557 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HFGJIHDG_02558 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_02559 2.9e-208 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_02560 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_02561 4.5e-61 hxlR K transcriptional
HFGJIHDG_02562 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HFGJIHDG_02563 1.6e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HFGJIHDG_02564 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
HFGJIHDG_02565 5.7e-65 nin S Competence protein J (ComJ)
HFGJIHDG_02566 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFGJIHDG_02567 1.3e-48 S Protein of unknown function (DUF2680)
HFGJIHDG_02568 1.1e-72 yckC S membrane
HFGJIHDG_02569 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HFGJIHDG_02570 7.8e-227 yciC S GTPases (G3E family)
HFGJIHDG_02571 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFGJIHDG_02572 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
HFGJIHDG_02573 7.1e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HFGJIHDG_02574 2.4e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HFGJIHDG_02575 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HFGJIHDG_02576 1.2e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFGJIHDG_02577 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HFGJIHDG_02578 8.7e-170 ycgM E Proline dehydrogenase
HFGJIHDG_02579 8.9e-147 ycgL S Predicted nucleotidyltransferase
HFGJIHDG_02580 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HFGJIHDG_02581 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HFGJIHDG_02582 9.1e-221 G COG0477 Permeases of the major facilitator superfamily
HFGJIHDG_02583 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
HFGJIHDG_02584 6.2e-108 tmrB S AAA domain
HFGJIHDG_02586 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFGJIHDG_02587 1.3e-113 ycgI S Domain of unknown function (DUF1989)
HFGJIHDG_02588 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HFGJIHDG_02589 2.2e-150 yqcI S YqcI/YcgG family
HFGJIHDG_02590 4.7e-114 ycgF E Lysine exporter protein LysE YggA
HFGJIHDG_02591 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_02592 8.1e-261 mdr EGP Major facilitator Superfamily
HFGJIHDG_02593 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFGJIHDG_02594 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HFGJIHDG_02595 1.5e-80 ycgB
HFGJIHDG_02596 5.5e-227 ycgA S Membrane
HFGJIHDG_02597 2.4e-209 amhX S amidohydrolase
HFGJIHDG_02598 1.5e-163 opuAC E glycine betaine
HFGJIHDG_02599 1.6e-138 opuAB P glycine betaine
HFGJIHDG_02600 3.9e-229 proV 3.6.3.32 E glycine betaine
HFGJIHDG_02601 2.6e-214 naiP P Uncharacterised MFS-type transporter YbfB
HFGJIHDG_02602 2.3e-193 yceH P Belongs to the TelA family
HFGJIHDG_02603 0.0 yceG S Putative component of 'biosynthetic module'
HFGJIHDG_02604 9.7e-138 terC P Protein of unknown function (DUF475)
HFGJIHDG_02605 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
HFGJIHDG_02606 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
HFGJIHDG_02607 2.8e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HFGJIHDG_02608 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFGJIHDG_02609 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HFGJIHDG_02610 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HFGJIHDG_02611 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
HFGJIHDG_02612 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HFGJIHDG_02613 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HFGJIHDG_02614 1e-188 S response regulator aspartate phosphatase
HFGJIHDG_02615 6.4e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
HFGJIHDG_02616 3.3e-266 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HFGJIHDG_02617 1.4e-256 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HFGJIHDG_02618 1.5e-175 ycdA S Domain of unknown function (DUF5105)
HFGJIHDG_02619 6.8e-170 yccK C Aldo keto reductase
HFGJIHDG_02620 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
HFGJIHDG_02621 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HFGJIHDG_02622 1.8e-139 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HFGJIHDG_02623 5.2e-45 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HFGJIHDG_02624 6.5e-99 yxaF K Transcriptional regulator
HFGJIHDG_02625 1e-241 lmrB EGP the major facilitator superfamily
HFGJIHDG_02626 7.9e-205 ycbU E Selenocysteine lyase
HFGJIHDG_02627 3.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFGJIHDG_02628 9.2e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HFGJIHDG_02629 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HFGJIHDG_02630 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HFGJIHDG_02631 5.3e-77 sleB 3.5.1.28 M Cell wall
HFGJIHDG_02632 5.6e-62 ycbP S Protein of unknown function (DUF2512)
HFGJIHDG_02633 3.5e-55 traF CO Thioredoxin
HFGJIHDG_02634 1.5e-62 mhqP S DoxX
HFGJIHDG_02635 1.3e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HFGJIHDG_02636 1.7e-108 ydfN C nitroreductase
HFGJIHDG_02637 2.3e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFGJIHDG_02638 1.8e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HFGJIHDG_02639 3.3e-124 ycbJ S Macrolide 2'-phosphotransferase
HFGJIHDG_02640 9.1e-170 glnL T Regulator
HFGJIHDG_02641 5.7e-207 phoQ 2.7.13.3 T Histidine kinase
HFGJIHDG_02642 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
HFGJIHDG_02643 2.7e-258 agcS E Sodium alanine symporter
HFGJIHDG_02644 1.6e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HFGJIHDG_02645 1.5e-256 mmuP E amino acid
HFGJIHDG_02646 2.1e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HFGJIHDG_02647 1.6e-214 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFGJIHDG_02648 2.5e-191 yceA S Belongs to the UPF0176 family
HFGJIHDG_02649 6.1e-42 ybfN
HFGJIHDG_02650 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HFGJIHDG_02651 1.9e-86 ybfM S SNARE associated Golgi protein
HFGJIHDG_02652 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFGJIHDG_02653 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFGJIHDG_02654 2.3e-193 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HFGJIHDG_02655 1.2e-82 K Helix-turn-helix XRE-family like proteins
HFGJIHDG_02656 9.2e-32
HFGJIHDG_02657 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HFGJIHDG_02659 3.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HFGJIHDG_02660 1e-16 S Protein of unknown function (DUF2651)
HFGJIHDG_02661 1.7e-259 glpT G -transporter
HFGJIHDG_02662 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HFGJIHDG_02663 2.3e-16 S Protein of unknown function (DUF2651)
HFGJIHDG_02664 6.5e-56
HFGJIHDG_02665 5.5e-292 ybeC E amino acid
HFGJIHDG_02666 9.2e-40 ybyB
HFGJIHDG_02667 8e-107 yqeB
HFGJIHDG_02668 7.5e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
HFGJIHDG_02669 2.5e-75 S Domain of unknown function (DUF4879)
HFGJIHDG_02670 9.2e-23
HFGJIHDG_02671 2.9e-194 V ABC-2 family transporter protein
HFGJIHDG_02672 1.7e-202 V COG0842 ABC-type multidrug transport system, permease component
HFGJIHDG_02673 2.5e-164 V COG1131 ABC-type multidrug transport system, ATPase component
HFGJIHDG_02674 4.6e-109 KT LuxR family transcriptional regulator
HFGJIHDG_02675 4.7e-197 T COG4585 Signal transduction histidine kinase
HFGJIHDG_02676 6.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFGJIHDG_02677 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HFGJIHDG_02678 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
HFGJIHDG_02679 5.8e-51 S LrgA family
HFGJIHDG_02680 2.9e-93 yxaC M effector of murein hydrolase
HFGJIHDG_02681 9.6e-163 dkgB S Aldo/keto reductase family
HFGJIHDG_02682 2.8e-18 dkgB S Aldo/keto reductase family
HFGJIHDG_02683 1.4e-107 2.1.1.113 L Belongs to the N(4) N(6)-methyltransferase family
HFGJIHDG_02684 2.4e-12
HFGJIHDG_02686 5.3e-42 D AAA domain
HFGJIHDG_02687 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFGJIHDG_02688 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFGJIHDG_02689 1.3e-223 ybbR S protein conserved in bacteria
HFGJIHDG_02690 3.9e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFGJIHDG_02691 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HFGJIHDG_02692 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HFGJIHDG_02698 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HFGJIHDG_02699 7.7e-85 ybbJ J acetyltransferase
HFGJIHDG_02700 9.2e-159 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFGJIHDG_02701 2.7e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFGJIHDG_02702 5.8e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HFGJIHDG_02703 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HFGJIHDG_02704 3.3e-236 ybbC 3.2.1.52 S protein conserved in bacteria
HFGJIHDG_02705 3e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HFGJIHDG_02706 2e-172 feuA P Iron-uptake system-binding protein
HFGJIHDG_02707 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_02708 6.1e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_02709 6e-108 ybbA S Putative esterase
HFGJIHDG_02710 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
HFGJIHDG_02711 6.7e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HFGJIHDG_02712 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HFGJIHDG_02713 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HFGJIHDG_02714 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFGJIHDG_02715 4.2e-220 glcP G Major Facilitator Superfamily
HFGJIHDG_02716 3.4e-39 S COG NOG14552 non supervised orthologous group
HFGJIHDG_02717 2.1e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
HFGJIHDG_02718 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HFGJIHDG_02719 1.7e-75 gerD
HFGJIHDG_02720 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HFGJIHDG_02721 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HFGJIHDG_02722 9.4e-77 ybaK S Protein of unknown function (DUF2521)
HFGJIHDG_02723 1.2e-82 yizA S Damage-inducible protein DinB
HFGJIHDG_02724 3.1e-144 ybaJ Q Methyltransferase domain
HFGJIHDG_02725 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HFGJIHDG_02726 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFGJIHDG_02727 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFGJIHDG_02728 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFGJIHDG_02729 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFGJIHDG_02730 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFGJIHDG_02731 4.7e-58 rplQ J Ribosomal protein L17
HFGJIHDG_02732 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFGJIHDG_02733 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFGJIHDG_02734 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFGJIHDG_02735 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HFGJIHDG_02736 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFGJIHDG_02737 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
HFGJIHDG_02738 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFGJIHDG_02739 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFGJIHDG_02740 4.1e-72 rplO J binds to the 23S rRNA
HFGJIHDG_02741 1.9e-23 rpmD J Ribosomal protein L30
HFGJIHDG_02742 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFGJIHDG_02743 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFGJIHDG_02744 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFGJIHDG_02745 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFGJIHDG_02746 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFGJIHDG_02747 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFGJIHDG_02748 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFGJIHDG_02749 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFGJIHDG_02750 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFGJIHDG_02751 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HFGJIHDG_02752 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFGJIHDG_02753 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFGJIHDG_02754 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFGJIHDG_02755 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFGJIHDG_02756 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFGJIHDG_02757 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFGJIHDG_02758 3e-105 rplD J Forms part of the polypeptide exit tunnel
HFGJIHDG_02759 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFGJIHDG_02760 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HFGJIHDG_02761 1.8e-181 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HFGJIHDG_02762 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFGJIHDG_02763 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFGJIHDG_02764 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFGJIHDG_02765 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFGJIHDG_02766 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HFGJIHDG_02767 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFGJIHDG_02768 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFGJIHDG_02769 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
HFGJIHDG_02770 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFGJIHDG_02771 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFGJIHDG_02772 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFGJIHDG_02773 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFGJIHDG_02774 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HFGJIHDG_02775 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFGJIHDG_02776 8.9e-116 sigH K Belongs to the sigma-70 factor family
HFGJIHDG_02777 4.2e-89 yacP S RNA-binding protein containing a PIN domain
HFGJIHDG_02778 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFGJIHDG_02779 4e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFGJIHDG_02780 1.8e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFGJIHDG_02781 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
HFGJIHDG_02782 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFGJIHDG_02783 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HFGJIHDG_02784 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HFGJIHDG_02785 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HFGJIHDG_02786 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HFGJIHDG_02787 1.1e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFGJIHDG_02788 0.0 clpC O Belongs to the ClpA ClpB family
HFGJIHDG_02789 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HFGJIHDG_02790 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HFGJIHDG_02791 7.5e-77 ctsR K Belongs to the CtsR family
HFGJIHDG_02792 3.4e-39 S COG NOG14552 non supervised orthologous group
HFGJIHDG_02797 2e-08
HFGJIHDG_02800 1.3e-07
HFGJIHDG_02802 3.4e-39 S COG NOG14552 non supervised orthologous group
HFGJIHDG_02803 3.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HFGJIHDG_02804 7.8e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFGJIHDG_02805 4.5e-29 yazB K transcriptional
HFGJIHDG_02806 1.1e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HFGJIHDG_02807 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFGJIHDG_02808 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HFGJIHDG_02809 1.9e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HFGJIHDG_02810 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HFGJIHDG_02811 8.9e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFGJIHDG_02812 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFGJIHDG_02813 3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HFGJIHDG_02814 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFGJIHDG_02815 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HFGJIHDG_02816 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFGJIHDG_02817 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFGJIHDG_02818 3e-270 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFGJIHDG_02819 1.4e-184 KLT serine threonine protein kinase
HFGJIHDG_02820 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
HFGJIHDG_02821 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HFGJIHDG_02824 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HFGJIHDG_02825 4.1e-57 divIC D Septum formation initiator
HFGJIHDG_02826 2.9e-103 yabQ S spore cortex biosynthesis protein
HFGJIHDG_02827 1.9e-49 yabP S Sporulation protein YabP
HFGJIHDG_02828 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HFGJIHDG_02829 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HFGJIHDG_02830 5.9e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFGJIHDG_02831 6.2e-91 spoVT K stage V sporulation protein
HFGJIHDG_02832 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFGJIHDG_02833 3.7e-40 yabK S Peptide ABC transporter permease
HFGJIHDG_02834 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFGJIHDG_02835 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HFGJIHDG_02836 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFGJIHDG_02837 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFGJIHDG_02838 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HFGJIHDG_02839 1.5e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HFGJIHDG_02840 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HFGJIHDG_02841 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFGJIHDG_02842 2.9e-27 sspF S DNA topological change
HFGJIHDG_02843 7.8e-39 veg S protein conserved in bacteria
HFGJIHDG_02844 8.4e-146 yabG S peptidase
HFGJIHDG_02845 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFGJIHDG_02846 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFGJIHDG_02847 2.7e-231 rpfB GH23 T protein conserved in bacteria
HFGJIHDG_02848 4.5e-143 tatD L hydrolase, TatD
HFGJIHDG_02849 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFGJIHDG_02850 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HFGJIHDG_02851 1.4e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFGJIHDG_02852 5.2e-47 yazA L endonuclease containing a URI domain
HFGJIHDG_02853 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HFGJIHDG_02854 7.7e-37 yabA L Involved in initiation control of chromosome replication
HFGJIHDG_02855 8.8e-145 yaaT S stage 0 sporulation protein
HFGJIHDG_02856 3.7e-182 holB 2.7.7.7 L DNA polymerase III
HFGJIHDG_02857 1.2e-71 yaaR S protein conserved in bacteria
HFGJIHDG_02858 7.5e-55 yaaQ S protein conserved in bacteria
HFGJIHDG_02859 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFGJIHDG_02860 6.4e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HFGJIHDG_02861 3.5e-189 yaaN P Belongs to the TelA family
HFGJIHDG_02862 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HFGJIHDG_02863 3.8e-30 csfB S Inhibitor of sigma-G Gin
HFGJIHDG_02866 3.4e-39 S COG NOG14552 non supervised orthologous group
HFGJIHDG_02867 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
HFGJIHDG_02868 3.6e-32 yaaL S Protein of unknown function (DUF2508)
HFGJIHDG_02869 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFGJIHDG_02870 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFGJIHDG_02871 1.1e-127 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFGJIHDG_02872 8.7e-157 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFGJIHDG_02873 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFGJIHDG_02874 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
HFGJIHDG_02875 1.7e-211 yaaH M Glycoside Hydrolase Family
HFGJIHDG_02876 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HFGJIHDG_02877 1.6e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HFGJIHDG_02878 1.3e-09
HFGJIHDG_02879 1.3e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HFGJIHDG_02880 3.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFGJIHDG_02881 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HFGJIHDG_02882 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HFGJIHDG_02883 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HFGJIHDG_02884 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HFGJIHDG_02885 6.3e-182 yaaC S YaaC-like Protein
HFGJIHDG_02886 3.4e-39 S COG NOG14552 non supervised orthologous group
HFGJIHDG_02887 1.1e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
HFGJIHDG_02888 3.2e-177 yuaG 3.4.21.72 S protein conserved in bacteria
HFGJIHDG_02889 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HFGJIHDG_02890 6.9e-73 yuaE S DinB superfamily
HFGJIHDG_02891 7.1e-109 yuaD S MOSC domain
HFGJIHDG_02892 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
HFGJIHDG_02893 3.2e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HFGJIHDG_02894 8.6e-96 yuaC K Belongs to the GbsR family
HFGJIHDG_02895 7.9e-94 yuaB
HFGJIHDG_02896 3.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
HFGJIHDG_02897 1.5e-144 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFGJIHDG_02898 2.5e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFGJIHDG_02899 1.4e-118 G Cupin
HFGJIHDG_02900 1.3e-51 yjcN
HFGJIHDG_02903 1.7e-130 S Aspartate phosphatase response regulator
HFGJIHDG_02904 1.5e-13
HFGJIHDG_02905 5e-17
HFGJIHDG_02907 6.8e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFGJIHDG_02908 6.5e-194 yubA S transporter activity
HFGJIHDG_02909 6.1e-185 ygjR S Oxidoreductase
HFGJIHDG_02910 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HFGJIHDG_02911 2e-53 mcpA NT chemotaxis protein
HFGJIHDG_02912 3.5e-179 mcpA NT chemotaxis protein
HFGJIHDG_02913 6e-224 mcpA NT chemotaxis protein
HFGJIHDG_02914 1.5e-235 mcpA NT chemotaxis protein
HFGJIHDG_02915 8.1e-221 mcpA NT chemotaxis protein
HFGJIHDG_02916 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HFGJIHDG_02917 1.4e-40
HFGJIHDG_02918 8e-188 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HFGJIHDG_02919 1e-72 yugU S Uncharacterised protein family UPF0047
HFGJIHDG_02920 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HFGJIHDG_02921 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HFGJIHDG_02922 3.2e-116 yugP S Zn-dependent protease
HFGJIHDG_02923 3.4e-18
HFGJIHDG_02924 2.5e-26 mstX S Membrane-integrating protein Mistic
HFGJIHDG_02925 5.3e-181 yugO P COG1226 Kef-type K transport systems
HFGJIHDG_02926 7e-71 yugN S YugN-like family
HFGJIHDG_02928 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
HFGJIHDG_02929 5.5e-118 ycaC Q Isochorismatase family
HFGJIHDG_02930 1.8e-228 yugK C Dehydrogenase
HFGJIHDG_02931 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HFGJIHDG_02932 1.8e-34 yuzA S Domain of unknown function (DUF378)
HFGJIHDG_02933 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HFGJIHDG_02934 1.6e-208 yugH 2.6.1.1 E Aminotransferase
HFGJIHDG_02935 2e-83 alaR K Transcriptional regulator
HFGJIHDG_02936 5.5e-155 yugF I Hydrolase
HFGJIHDG_02937 1.4e-40 yugE S Domain of unknown function (DUF1871)
HFGJIHDG_02938 3.3e-222 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HFGJIHDG_02939 3.1e-229 T PhoQ Sensor
HFGJIHDG_02940 7.7e-67 kapB G Kinase associated protein B
HFGJIHDG_02941 3.1e-118 kapD L the KinA pathway to sporulation
HFGJIHDG_02942 1.5e-185 yuxJ EGP Major facilitator Superfamily
HFGJIHDG_02943 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HFGJIHDG_02944 2.2e-72 yuxK S protein conserved in bacteria
HFGJIHDG_02945 9.3e-74 yufK S Family of unknown function (DUF5366)
HFGJIHDG_02946 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HFGJIHDG_02947 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
HFGJIHDG_02948 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HFGJIHDG_02949 2.8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HFGJIHDG_02950 8.4e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HFGJIHDG_02951 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HFGJIHDG_02952 2.3e-12
HFGJIHDG_02953 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HFGJIHDG_02954 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFGJIHDG_02955 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFGJIHDG_02956 1.7e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFGJIHDG_02957 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFGJIHDG_02958 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFGJIHDG_02959 1.1e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HFGJIHDG_02960 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
HFGJIHDG_02961 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFGJIHDG_02962 6e-276 comP 2.7.13.3 T Histidine kinase
HFGJIHDG_02964 8.9e-98 comQ H Belongs to the FPP GGPP synthase family
HFGJIHDG_02967 1.2e-50 yuzC
HFGJIHDG_02968 8.5e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HFGJIHDG_02969 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFGJIHDG_02970 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
HFGJIHDG_02971 7.2e-68 yueI S Protein of unknown function (DUF1694)
HFGJIHDG_02972 2.8e-38 yueH S YueH-like protein
HFGJIHDG_02973 6.4e-34 yueG S Spore germination protein gerPA/gerPF
HFGJIHDG_02974 3.6e-186 yueF S transporter activity
HFGJIHDG_02975 1.6e-22 S Protein of unknown function (DUF2642)
HFGJIHDG_02976 8.3e-96 yueE S phosphohydrolase
HFGJIHDG_02977 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_02978 8.5e-76 yueC S Family of unknown function (DUF5383)
HFGJIHDG_02979 0.0 esaA S type VII secretion protein EsaA
HFGJIHDG_02980 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HFGJIHDG_02981 1.4e-202 essB S WXG100 protein secretion system (Wss), protein YukC
HFGJIHDG_02982 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
HFGJIHDG_02983 3.3e-46 esxA S Belongs to the WXG100 family
HFGJIHDG_02984 4.2e-228 yukF QT Transcriptional regulator
HFGJIHDG_02985 3.9e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HFGJIHDG_02986 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HFGJIHDG_02987 1.1e-33 mbtH S MbtH-like protein
HFGJIHDG_02988 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_02989 3.6e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HFGJIHDG_02990 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HFGJIHDG_02991 8.6e-218 entC 5.4.4.2 HQ Isochorismate synthase
HFGJIHDG_02992 2.4e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HFGJIHDG_02993 4.4e-163 besA S Putative esterase
HFGJIHDG_02994 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
HFGJIHDG_02995 1.5e-101 bioY S Biotin biosynthesis protein
HFGJIHDG_02996 1.2e-207 yuiF S antiporter
HFGJIHDG_02997 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HFGJIHDG_02998 1.6e-77 yuiD S protein conserved in bacteria
HFGJIHDG_02999 1.3e-116 yuiC S protein conserved in bacteria
HFGJIHDG_03000 9.9e-28 yuiB S Putative membrane protein
HFGJIHDG_03001 9.4e-236 yumB 1.6.99.3 C NADH dehydrogenase
HFGJIHDG_03002 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HFGJIHDG_03004 1.1e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFGJIHDG_03005 4.8e-29
HFGJIHDG_03006 1e-69 CP Membrane
HFGJIHDG_03007 1.5e-121 V ABC transporter
HFGJIHDG_03009 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
HFGJIHDG_03011 2.3e-26 K helix_turn_helix, mercury resistance
HFGJIHDG_03012 1.6e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HFGJIHDG_03013 1.1e-62 erpA S Belongs to the HesB IscA family
HFGJIHDG_03014 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFGJIHDG_03015 3.2e-212 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFGJIHDG_03016 9.2e-39 yuzB S Belongs to the UPF0349 family
HFGJIHDG_03017 2.7e-207 yutJ 1.6.99.3 C NADH dehydrogenase
HFGJIHDG_03018 1.1e-53 yuzD S protein conserved in bacteria
HFGJIHDG_03019 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HFGJIHDG_03020 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HFGJIHDG_03021 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFGJIHDG_03022 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HFGJIHDG_03023 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
HFGJIHDG_03024 3e-195 yutH S Spore coat protein
HFGJIHDG_03025 3.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HFGJIHDG_03026 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFGJIHDG_03027 6.8e-72 yutE S Protein of unknown function DUF86
HFGJIHDG_03028 1.7e-47 yutD S protein conserved in bacteria
HFGJIHDG_03029 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HFGJIHDG_03030 1.5e-191 lytH M Peptidase, M23
HFGJIHDG_03031 2.5e-130 yunB S Sporulation protein YunB (Spo_YunB)
HFGJIHDG_03032 3.5e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HFGJIHDG_03033 1.1e-144 yunE S membrane transporter protein
HFGJIHDG_03034 1.5e-168 yunF S Protein of unknown function DUF72
HFGJIHDG_03035 2.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
HFGJIHDG_03036 1.5e-261 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HFGJIHDG_03037 1.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
HFGJIHDG_03038 1.6e-73
HFGJIHDG_03039 4.1e-212 blt EGP Major facilitator Superfamily
HFGJIHDG_03040 5.6e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HFGJIHDG_03041 5.2e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HFGJIHDG_03042 1.6e-165 bsn L Ribonuclease
HFGJIHDG_03043 2.7e-205 msmX P Belongs to the ABC transporter superfamily
HFGJIHDG_03044 3.6e-134 yurK K UTRA
HFGJIHDG_03045 1.5e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HFGJIHDG_03046 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
HFGJIHDG_03047 9.8e-158 yurN G Binding-protein-dependent transport system inner membrane component
HFGJIHDG_03048 1.4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HFGJIHDG_03049 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HFGJIHDG_03050 5e-165 K helix_turn_helix, mercury resistance
HFGJIHDG_03052 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HFGJIHDG_03053 3.1e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HFGJIHDG_03054 2.2e-24 yncE S Protein of unknown function (DUF2691)
HFGJIHDG_03055 1e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HFGJIHDG_03056 8.7e-270 sufB O FeS cluster assembly
HFGJIHDG_03057 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HFGJIHDG_03058 1.4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFGJIHDG_03059 1.2e-244 sufD O assembly protein SufD
HFGJIHDG_03060 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HFGJIHDG_03061 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFGJIHDG_03062 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
HFGJIHDG_03063 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HFGJIHDG_03064 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFGJIHDG_03065 1.5e-56 yusD S SCP-2 sterol transfer family
HFGJIHDG_03066 1.6e-54 yusE CO Thioredoxin
HFGJIHDG_03067 1.4e-62 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HFGJIHDG_03068 3.7e-40 yusG S Protein of unknown function (DUF2553)
HFGJIHDG_03069 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HFGJIHDG_03070 6.2e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HFGJIHDG_03071 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HFGJIHDG_03072 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
HFGJIHDG_03073 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HFGJIHDG_03074 3.2e-164 fadM E Proline dehydrogenase
HFGJIHDG_03075 5.7e-42
HFGJIHDG_03076 1.1e-53 yusN M Coat F domain
HFGJIHDG_03077 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
HFGJIHDG_03078 4e-287 yusP P Major facilitator superfamily
HFGJIHDG_03079 1e-154 ywbI2 K Transcriptional regulator
HFGJIHDG_03080 4.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HFGJIHDG_03081 2.4e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFGJIHDG_03082 3.3e-39 yusU S Protein of unknown function (DUF2573)
HFGJIHDG_03083 3.1e-150 yusV 3.6.3.34 HP ABC transporter
HFGJIHDG_03084 7.2e-45 S YusW-like protein
HFGJIHDG_03085 0.0 pepF2 E COG1164 Oligoendopeptidase F
HFGJIHDG_03086 1.1e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HFGJIHDG_03087 4.7e-79 dps P Belongs to the Dps family
HFGJIHDG_03088 1.9e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFGJIHDG_03089 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_03090 2.2e-249 cssS 2.7.13.3 T PhoQ Sensor
HFGJIHDG_03091 3.4e-24
HFGJIHDG_03092 2.2e-157 yuxN K Transcriptional regulator
HFGJIHDG_03093 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFGJIHDG_03094 6.6e-24 S Protein of unknown function (DUF3970)
HFGJIHDG_03095 6e-258 gerAA EG Spore germination protein
HFGJIHDG_03096 3.6e-186 gerAB E Spore germination protein
HFGJIHDG_03097 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
HFGJIHDG_03098 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFGJIHDG_03099 2.3e-193 vraS 2.7.13.3 T Histidine kinase
HFGJIHDG_03100 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HFGJIHDG_03101 7.4e-126 liaG S Putative adhesin
HFGJIHDG_03102 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HFGJIHDG_03103 5.3e-44 liaI S membrane
HFGJIHDG_03104 1.8e-226 yvqJ EGP Major facilitator Superfamily
HFGJIHDG_03105 3.1e-101 yvqK 2.5.1.17 S Adenosyltransferase
HFGJIHDG_03106 7.2e-220 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HFGJIHDG_03107 1.7e-177 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_03108 2.7e-166 yvrC P ABC transporter substrate-binding protein
HFGJIHDG_03109 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HFGJIHDG_03110 4.2e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
HFGJIHDG_03111 0.0 T PhoQ Sensor
HFGJIHDG_03112 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_03113 7.3e-36
HFGJIHDG_03114 3.8e-102 yvrI K RNA polymerase
HFGJIHDG_03115 1.6e-15 S YvrJ protein family
HFGJIHDG_03116 3.9e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
HFGJIHDG_03117 2.7e-65 yvrL S Regulatory protein YrvL
HFGJIHDG_03118 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
HFGJIHDG_03119 7.6e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_03120 3.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_03121 4e-178 fhuD P ABC transporter
HFGJIHDG_03122 3.1e-127 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HFGJIHDG_03123 7e-235 yvsH E Arginine ornithine antiporter
HFGJIHDG_03124 5.2e-13 S Small spore protein J (Spore_SspJ)
HFGJIHDG_03125 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HFGJIHDG_03126 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HFGJIHDG_03127 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HFGJIHDG_03128 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HFGJIHDG_03129 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
HFGJIHDG_03130 8.6e-114 yfiK K Regulator
HFGJIHDG_03131 6.2e-178 T Histidine kinase
HFGJIHDG_03132 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HFGJIHDG_03133 1.3e-191 yfiM V ABC-2 type transporter
HFGJIHDG_03134 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
HFGJIHDG_03135 1.1e-155 yvgN S reductase
HFGJIHDG_03136 2.7e-85 yvgO
HFGJIHDG_03137 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HFGJIHDG_03138 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HFGJIHDG_03139 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HFGJIHDG_03140 0.0 helD 3.6.4.12 L DNA helicase
HFGJIHDG_03141 2.9e-97 yvgT S membrane
HFGJIHDG_03142 3.7e-140 S Metallo-peptidase family M12
HFGJIHDG_03143 6e-73 bdbC O Required for disulfide bond formation in some proteins
HFGJIHDG_03144 7.5e-102 bdbD O Thioredoxin
HFGJIHDG_03145 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HFGJIHDG_03146 0.0 copA 3.6.3.54 P P-type ATPase
HFGJIHDG_03147 2.6e-29 copZ P Heavy-metal-associated domain
HFGJIHDG_03148 3.7e-48 csoR S transcriptional
HFGJIHDG_03149 4.1e-192 yvaA 1.1.1.371 S Oxidoreductase
HFGJIHDG_03150 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFGJIHDG_03151 8.4e-159 K Helix-turn-helix XRE-family like proteins
HFGJIHDG_03152 2.8e-216 ynfM EGP Major Facilitator Superfamily
HFGJIHDG_03153 9.1e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
HFGJIHDG_03154 1.1e-141 S Amidohydrolase
HFGJIHDG_03155 3.2e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFGJIHDG_03156 2.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
HFGJIHDG_03157 9.3e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFGJIHDG_03158 1e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HFGJIHDG_03159 1.1e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HFGJIHDG_03160 1.7e-120 tcyL P Binding-protein-dependent transport system inner membrane component
HFGJIHDG_03161 5.4e-147 tcyK M Bacterial periplasmic substrate-binding proteins
HFGJIHDG_03162 3.9e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
HFGJIHDG_03163 3e-101 ytmI K Acetyltransferase (GNAT) domain
HFGJIHDG_03164 7.2e-161 ytlI K LysR substrate binding domain
HFGJIHDG_03165 4.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HFGJIHDG_03166 1.1e-47 yrdF K ribonuclease inhibitor
HFGJIHDG_03167 7.9e-56
HFGJIHDG_03169 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HFGJIHDG_03170 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFGJIHDG_03171 1.6e-142 est 3.1.1.1 S Carboxylesterase
HFGJIHDG_03172 4.8e-24 secG U Preprotein translocase subunit SecG
HFGJIHDG_03173 6e-35 yvzC K Transcriptional
HFGJIHDG_03174 1e-69 K transcriptional
HFGJIHDG_03175 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
HFGJIHDG_03176 8.8e-53 yodB K transcriptional
HFGJIHDG_03177 1.8e-259 T His Kinase A (phosphoacceptor) domain
HFGJIHDG_03178 1.4e-121 K Transcriptional regulatory protein, C terminal
HFGJIHDG_03179 5.9e-135 mutG S ABC-2 family transporter protein
HFGJIHDG_03180 4.9e-123 spaE S ABC-2 family transporter protein
HFGJIHDG_03181 1.2e-126 mutF V ABC transporter, ATP-binding protein
HFGJIHDG_03182 5.2e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HFGJIHDG_03183 3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFGJIHDG_03184 1.2e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HFGJIHDG_03185 2.9e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HFGJIHDG_03186 4.3e-76 yvbF K Belongs to the GbsR family
HFGJIHDG_03187 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HFGJIHDG_03188 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFGJIHDG_03189 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HFGJIHDG_03190 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HFGJIHDG_03191 3.5e-97 yvbF K Belongs to the GbsR family
HFGJIHDG_03192 9.8e-104 yvbG U UPF0056 membrane protein
HFGJIHDG_03193 6.4e-120 exoY M Membrane
HFGJIHDG_03194 0.0 tcaA S response to antibiotic
HFGJIHDG_03195 1.5e-80 yvbK 3.1.3.25 K acetyltransferase
HFGJIHDG_03196 6.2e-211 EGP Major facilitator Superfamily
HFGJIHDG_03197 3.3e-177
HFGJIHDG_03198 4.1e-124 S GlcNAc-PI de-N-acetylase
HFGJIHDG_03199 2.1e-142 C WbqC-like protein family
HFGJIHDG_03200 1e-146 M Protein involved in cellulose biosynthesis
HFGJIHDG_03201 6.9e-226 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HFGJIHDG_03202 4e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
HFGJIHDG_03203 2.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HFGJIHDG_03204 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFGJIHDG_03205 3.2e-234 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HFGJIHDG_03206 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFGJIHDG_03207 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HFGJIHDG_03208 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFGJIHDG_03209 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HFGJIHDG_03210 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFGJIHDG_03211 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HFGJIHDG_03213 7.4e-253 araE EGP Major facilitator Superfamily
HFGJIHDG_03214 1.4e-203 araR K transcriptional
HFGJIHDG_03215 8.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFGJIHDG_03217 2.4e-156 yvbU K Transcriptional regulator
HFGJIHDG_03218 7.7e-158 yvbV EG EamA-like transporter family
HFGJIHDG_03219 3.2e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HFGJIHDG_03220 4.2e-258
HFGJIHDG_03221 2.1e-182 purR7 5.1.1.1 K Transcriptional regulator
HFGJIHDG_03222 3.4e-115 yyaS S Membrane
HFGJIHDG_03223 7e-164 3.1.3.104 S hydrolases of the HAD superfamily
HFGJIHDG_03224 1.9e-150 ybbH_1 K RpiR family transcriptional regulator
HFGJIHDG_03225 1.2e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
HFGJIHDG_03226 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
HFGJIHDG_03227 2.2e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HFGJIHDG_03228 2.8e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HFGJIHDG_03229 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HFGJIHDG_03230 1.3e-218 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFGJIHDG_03231 1.5e-119 yvfI K COG2186 Transcriptional regulators
HFGJIHDG_03232 2.5e-303 yvfH C L-lactate permease
HFGJIHDG_03233 1.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HFGJIHDG_03234 2.7e-32 yvfG S YvfG protein
HFGJIHDG_03235 1.9e-183 yvfF GM Exopolysaccharide biosynthesis protein
HFGJIHDG_03236 4.1e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HFGJIHDG_03237 4.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HFGJIHDG_03238 6.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HFGJIHDG_03239 1.6e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFGJIHDG_03240 7.5e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HFGJIHDG_03241 1.1e-203 epsI GM pyruvyl transferase
HFGJIHDG_03242 1.9e-192 epsH GT2 S Glycosyltransferase like family 2
HFGJIHDG_03243 7.7e-205 epsG S EpsG family
HFGJIHDG_03244 7.9e-213 epsF GT4 M Glycosyl transferases group 1
HFGJIHDG_03245 2.6e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HFGJIHDG_03246 7.4e-219 epsD GT4 M Glycosyl transferase 4-like
HFGJIHDG_03247 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HFGJIHDG_03248 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HFGJIHDG_03249 1.6e-118 ywqC M biosynthesis protein
HFGJIHDG_03250 1.9e-77 slr K transcriptional
HFGJIHDG_03251 3.8e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HFGJIHDG_03253 3.7e-96 ywjB H RibD C-terminal domain
HFGJIHDG_03254 3.4e-112 yyaS S Membrane
HFGJIHDG_03255 3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFGJIHDG_03256 1.6e-93 padC Q Phenolic acid decarboxylase
HFGJIHDG_03257 1.5e-38 S Protein of unknown function (DUF1433)
HFGJIHDG_03258 2.3e-15 S Protein of unknown function (DUF1433)
HFGJIHDG_03259 2.2e-17 S Protein of unknown function (DUF1433)
HFGJIHDG_03260 9.8e-18 S Protein of unknown function (DUF1433)
HFGJIHDG_03261 7.3e-264 I Pfam Lipase (class 3)
HFGJIHDG_03262 2.6e-33
HFGJIHDG_03264 1.6e-290 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HFGJIHDG_03265 2.3e-218 rafB P LacY proton/sugar symporter
HFGJIHDG_03266 9.6e-183 scrR K transcriptional
HFGJIHDG_03267 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFGJIHDG_03268 3.7e-162 yraN K Transcriptional regulator
HFGJIHDG_03269 6.9e-209 yraM S PrpF protein
HFGJIHDG_03270 2.1e-247 EGP Sugar (and other) transporter
HFGJIHDG_03271 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HFGJIHDG_03272 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HFGJIHDG_03273 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HFGJIHDG_03274 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HFGJIHDG_03275 1.5e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFGJIHDG_03276 4.8e-79 M Ribonuclease
HFGJIHDG_03277 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HFGJIHDG_03278 4.7e-36 crh G Phosphocarrier protein Chr
HFGJIHDG_03279 3.1e-170 whiA K May be required for sporulation
HFGJIHDG_03280 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HFGJIHDG_03281 1.1e-166 rapZ S Displays ATPase and GTPase activities
HFGJIHDG_03282 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HFGJIHDG_03283 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFGJIHDG_03284 1.3e-124 usp CBM50 M protein conserved in bacteria
HFGJIHDG_03285 2.5e-275 S COG0457 FOG TPR repeat
HFGJIHDG_03286 4e-190 sasA T Histidine kinase
HFGJIHDG_03287 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_03288 1.1e-54
HFGJIHDG_03289 0.0 msbA2 3.6.3.44 V ABC transporter
HFGJIHDG_03290 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HFGJIHDG_03291 4.9e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFGJIHDG_03292 6e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HFGJIHDG_03293 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFGJIHDG_03294 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HFGJIHDG_03295 1.4e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFGJIHDG_03296 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HFGJIHDG_03297 1.1e-206 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HFGJIHDG_03298 3.5e-137 yvpB NU protein conserved in bacteria
HFGJIHDG_03299 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HFGJIHDG_03300 1.4e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HFGJIHDG_03301 5.8e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFGJIHDG_03302 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFGJIHDG_03303 1e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFGJIHDG_03304 3.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFGJIHDG_03305 2.3e-133 yvoA K transcriptional
HFGJIHDG_03306 4.4e-103 yxaF K Transcriptional regulator
HFGJIHDG_03307 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HFGJIHDG_03308 1.5e-40 yvlD S Membrane
HFGJIHDG_03309 9.6e-26 pspB KT PspC domain
HFGJIHDG_03310 1.2e-165 yvlB S Putative adhesin
HFGJIHDG_03311 6.1e-49 yvlA
HFGJIHDG_03312 2.2e-32 yvkN
HFGJIHDG_03313 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFGJIHDG_03314 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFGJIHDG_03315 7.6e-33 csbA S protein conserved in bacteria
HFGJIHDG_03316 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HFGJIHDG_03317 1.7e-108 yvkB K Transcriptional regulator
HFGJIHDG_03318 5.6e-226 yvkA EGP Major facilitator Superfamily
HFGJIHDG_03319 2.2e-08 L Transposase, Mutator family
HFGJIHDG_03320 2.3e-52 L For insertion sequence element IS256 in transposon Tn4001
HFGJIHDG_03321 2.6e-14 bacT Q Thioesterase domain
HFGJIHDG_03323 4e-174 S Psort location CytoplasmicMembrane, score
HFGJIHDG_03324 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFGJIHDG_03325 1.5e-55 swrA S Swarming motility protein
HFGJIHDG_03326 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HFGJIHDG_03327 8.6e-225 ywoF P Right handed beta helix region
HFGJIHDG_03328 1.2e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HFGJIHDG_03329 2.3e-122 ftsE D cell division ATP-binding protein FtsE
HFGJIHDG_03330 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
HFGJIHDG_03331 3e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HFGJIHDG_03332 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFGJIHDG_03333 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFGJIHDG_03334 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFGJIHDG_03335 6.8e-68
HFGJIHDG_03336 4.5e-10 fliT S bacterial-type flagellum organization
HFGJIHDG_03337 3e-66 fliS N flagellar protein FliS
HFGJIHDG_03338 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HFGJIHDG_03339 7.1e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HFGJIHDG_03340 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HFGJIHDG_03341 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HFGJIHDG_03342 1.2e-79 yviE
HFGJIHDG_03343 2.3e-162 flgL N Belongs to the bacterial flagellin family
HFGJIHDG_03344 1.8e-273 flgK N flagellar hook-associated protein
HFGJIHDG_03345 8.9e-81 flgN NOU FlgN protein
HFGJIHDG_03346 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
HFGJIHDG_03347 4.1e-74 yvyF S flagellar protein
HFGJIHDG_03348 4.6e-68 comFC S Phosphoribosyl transferase domain
HFGJIHDG_03349 1.7e-42 comFB S Late competence development protein ComFB
HFGJIHDG_03350 7.1e-256 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HFGJIHDG_03351 1.4e-158 degV S protein conserved in bacteria
HFGJIHDG_03352 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFGJIHDG_03353 1.4e-180 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HFGJIHDG_03354 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HFGJIHDG_03355 2.3e-165 yvhJ K Transcriptional regulator
HFGJIHDG_03356 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HFGJIHDG_03357 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HFGJIHDG_03358 3.4e-143 tuaG GT2 M Glycosyltransferase like family 2
HFGJIHDG_03359 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HFGJIHDG_03360 5.2e-254 tuaE M Teichuronic acid biosynthesis protein
HFGJIHDG_03361 3.4e-247 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFGJIHDG_03362 2.6e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HFGJIHDG_03363 6.1e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFGJIHDG_03364 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HFGJIHDG_03365 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HFGJIHDG_03366 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HFGJIHDG_03367 2.3e-48
HFGJIHDG_03368 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HFGJIHDG_03369 4.5e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFGJIHDG_03370 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HFGJIHDG_03371 1.1e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HFGJIHDG_03372 1.7e-151 tagG GM Transport permease protein
HFGJIHDG_03373 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HFGJIHDG_03374 7.8e-280 M Glycosyltransferase like family 2
HFGJIHDG_03375 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HFGJIHDG_03376 1.4e-141 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HFGJIHDG_03377 5.5e-217 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HFGJIHDG_03378 2.3e-239 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFGJIHDG_03379 7.7e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HFGJIHDG_03380 2.8e-263 gerBA EG Spore germination protein
HFGJIHDG_03381 7.8e-197 gerBB E Spore germination protein
HFGJIHDG_03382 1.1e-209 gerAC S Spore germination protein
HFGJIHDG_03383 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
HFGJIHDG_03384 4.9e-249 ywtG EGP Major facilitator Superfamily
HFGJIHDG_03385 7.2e-178 ywtF K Transcriptional regulator
HFGJIHDG_03386 1.8e-156 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HFGJIHDG_03387 5.5e-34 yttA 2.7.13.3 S Pfam Transposase IS66
HFGJIHDG_03388 6.6e-237 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HFGJIHDG_03389 1.3e-20 ywtC
HFGJIHDG_03390 2.8e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HFGJIHDG_03391 2.3e-70 pgsC S biosynthesis protein
HFGJIHDG_03392 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HFGJIHDG_03393 4.5e-184 gerKA EG Spore germination protein
HFGJIHDG_03394 3.1e-190 gerKB E Spore germination protein
HFGJIHDG_03395 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
HFGJIHDG_03396 3.2e-178 rbsR K transcriptional
HFGJIHDG_03397 3.1e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFGJIHDG_03398 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFGJIHDG_03399 2.4e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HFGJIHDG_03400 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HFGJIHDG_03401 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HFGJIHDG_03402 3.4e-89 batE T Sh3 type 3 domain protein
HFGJIHDG_03403 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HFGJIHDG_03404 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HFGJIHDG_03405 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HFGJIHDG_03406 2.6e-166 alsR K LysR substrate binding domain
HFGJIHDG_03408 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HFGJIHDG_03409 4.4e-126 ywrJ
HFGJIHDG_03410 6e-131 cotB
HFGJIHDG_03411 3.2e-211 cotH M Spore Coat
HFGJIHDG_03412 2.2e-09
HFGJIHDG_03413 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFGJIHDG_03415 6.5e-298 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HFGJIHDG_03416 2.5e-83 ywrC K Transcriptional regulator
HFGJIHDG_03417 9.5e-101 ywrB P Chromate transporter
HFGJIHDG_03418 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
HFGJIHDG_03420 1.7e-91 ywqN S NAD(P)H-dependent
HFGJIHDG_03421 9e-156 K Transcriptional regulator
HFGJIHDG_03422 1.6e-131 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HFGJIHDG_03423 1.7e-90
HFGJIHDG_03424 8.4e-16 S SMI1 / KNR4 family
HFGJIHDG_03425 4.3e-66 S SMI1 / KNR4 family (SUKH-1)
HFGJIHDG_03426 1.1e-87 ywqJ S Pre-toxin TG
HFGJIHDG_03427 2.4e-41 S Protein of unknown function (DUF2004)
HFGJIHDG_03428 2.6e-49
HFGJIHDG_03429 2.4e-301 ywqJ S Pre-toxin TG
HFGJIHDG_03430 4.3e-37 ywqI S Family of unknown function (DUF5344)
HFGJIHDG_03431 1.4e-21 S Domain of unknown function (DUF5082)
HFGJIHDG_03432 1.3e-145 ywqG S Domain of unknown function (DUF1963)
HFGJIHDG_03433 1.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFGJIHDG_03434 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HFGJIHDG_03435 1.6e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HFGJIHDG_03436 4.1e-109 ywqC M biosynthesis protein
HFGJIHDG_03437 1.3e-14
HFGJIHDG_03438 1.6e-307 ywqB S SWIM zinc finger
HFGJIHDG_03439 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HFGJIHDG_03440 1.7e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HFGJIHDG_03441 7.5e-138 glcR K DeoR C terminal sensor domain
HFGJIHDG_03442 3.7e-57 ssbB L Single-stranded DNA-binding protein
HFGJIHDG_03443 4e-62 ywpG
HFGJIHDG_03444 2.5e-68 ywpF S YwpF-like protein
HFGJIHDG_03445 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFGJIHDG_03446 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFGJIHDG_03447 5.2e-198 S aspartate phosphatase
HFGJIHDG_03448 7e-142 flhP N flagellar basal body
HFGJIHDG_03449 4.2e-128 flhO N flagellar basal body
HFGJIHDG_03450 2.7e-180 mbl D Rod shape-determining protein
HFGJIHDG_03451 1.8e-44 spoIIID K Stage III sporulation protein D
HFGJIHDG_03452 2.5e-71 ywoH K transcriptional
HFGJIHDG_03453 4.1e-212 ywoG EGP Major facilitator Superfamily
HFGJIHDG_03454 1.1e-275 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HFGJIHDG_03455 1.6e-244 ywoD EGP Major facilitator superfamily
HFGJIHDG_03456 2.8e-102 phzA Q Isochorismatase family
HFGJIHDG_03457 2.5e-228 amt P Ammonium transporter
HFGJIHDG_03458 2e-58 nrgB K Belongs to the P(II) protein family
HFGJIHDG_03459 5.1e-207 ftsW D Belongs to the SEDS family
HFGJIHDG_03460 4.6e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HFGJIHDG_03461 2.1e-70 ywnJ S VanZ like family
HFGJIHDG_03462 1.3e-119 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HFGJIHDG_03463 4.9e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HFGJIHDG_03464 1.2e-10 ywnC S Family of unknown function (DUF5362)
HFGJIHDG_03465 4.2e-69 ywnF S Family of unknown function (DUF5392)
HFGJIHDG_03466 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFGJIHDG_03467 1.2e-51 ywnC S Family of unknown function (DUF5362)
HFGJIHDG_03468 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HFGJIHDG_03470 1.8e-66 ywnA K Transcriptional regulator
HFGJIHDG_03471 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HFGJIHDG_03472 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HFGJIHDG_03473 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HFGJIHDG_03474 1.4e-10 csbD K CsbD-like
HFGJIHDG_03475 2.3e-81 ywmF S Peptidase M50
HFGJIHDG_03476 2.8e-93 S response regulator aspartate phosphatase
HFGJIHDG_03477 1.6e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HFGJIHDG_03478 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HFGJIHDG_03480 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HFGJIHDG_03481 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HFGJIHDG_03482 4e-179 spoIID D Stage II sporulation protein D
HFGJIHDG_03483 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFGJIHDG_03484 2.2e-134 ywmB S TATA-box binding
HFGJIHDG_03485 4.8e-32 ywzB S membrane
HFGJIHDG_03486 8.7e-89 ywmA
HFGJIHDG_03487 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HFGJIHDG_03488 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFGJIHDG_03489 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFGJIHDG_03490 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFGJIHDG_03491 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFGJIHDG_03492 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFGJIHDG_03493 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFGJIHDG_03494 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
HFGJIHDG_03495 2.1e-61 atpI S ATP synthase
HFGJIHDG_03496 2.3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFGJIHDG_03497 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFGJIHDG_03498 1.7e-96 ywlG S Belongs to the UPF0340 family
HFGJIHDG_03499 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HFGJIHDG_03500 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFGJIHDG_03501 1.3e-83 mntP P Probably functions as a manganese efflux pump
HFGJIHDG_03502 1.5e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFGJIHDG_03503 1.1e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HFGJIHDG_03504 8.9e-119 spoIIR S stage II sporulation protein R
HFGJIHDG_03505 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
HFGJIHDG_03507 4.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFGJIHDG_03508 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFGJIHDG_03509 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFGJIHDG_03510 7e-93 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HFGJIHDG_03511 6.8e-157 ywkB S Membrane transport protein
HFGJIHDG_03512 0.0 sfcA 1.1.1.38 C malic enzyme
HFGJIHDG_03513 1.1e-101 tdk 2.7.1.21 F thymidine kinase
HFGJIHDG_03514 1.1e-32 rpmE J Binds the 23S rRNA
HFGJIHDG_03515 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HFGJIHDG_03516 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HFGJIHDG_03517 1.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFGJIHDG_03518 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFGJIHDG_03519 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HFGJIHDG_03520 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
HFGJIHDG_03521 2.4e-92 ywjG S Domain of unknown function (DUF2529)
HFGJIHDG_03522 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFGJIHDG_03523 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFGJIHDG_03524 0.0 fadF C COG0247 Fe-S oxidoreductase
HFGJIHDG_03525 1.1e-217 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HFGJIHDG_03526 1.3e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HFGJIHDG_03527 4.2e-43 ywjC
HFGJIHDG_03528 0.0 ywjA V ABC transporter
HFGJIHDG_03529 7.9e-296 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFGJIHDG_03530 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFGJIHDG_03531 6.1e-120 narI 1.7.5.1 C nitrate reductase, gamma
HFGJIHDG_03532 7.9e-89 narJ 1.7.5.1 C nitrate reductase
HFGJIHDG_03533 1.8e-294 narH 1.7.5.1 C Nitrate reductase, beta
HFGJIHDG_03534 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFGJIHDG_03535 1.6e-55 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFGJIHDG_03536 1.7e-84 arfM T cyclic nucleotide binding
HFGJIHDG_03537 9.1e-138 ywiC S YwiC-like protein
HFGJIHDG_03538 5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
HFGJIHDG_03539 2.7e-211 narK P COG2223 Nitrate nitrite transporter
HFGJIHDG_03540 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HFGJIHDG_03541 2.9e-43 ywiB S protein conserved in bacteria
HFGJIHDG_03542 2.9e-77 S aspartate phosphatase
HFGJIHDG_03544 9.7e-29 ydcG K sequence-specific DNA binding
HFGJIHDG_03545 3.6e-31
HFGJIHDG_03547 9.9e-75 CP Membrane
HFGJIHDG_03550 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
HFGJIHDG_03551 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HFGJIHDG_03552 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HFGJIHDG_03553 8e-81
HFGJIHDG_03554 6.4e-93 ywhD S YwhD family
HFGJIHDG_03555 1.2e-117 ywhC S Peptidase family M50
HFGJIHDG_03556 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HFGJIHDG_03557 4.9e-67 ywhA K Transcriptional regulator
HFGJIHDG_03558 1.9e-245 yhdG_1 E C-terminus of AA_permease
HFGJIHDG_03559 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
HFGJIHDG_03560 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HFGJIHDG_03561 6.9e-36 ywzC S Belongs to the UPF0741 family
HFGJIHDG_03562 6.6e-110 rsfA_1
HFGJIHDG_03563 9.7e-52 padR K PadR family transcriptional regulator
HFGJIHDG_03564 1.1e-93 S membrane
HFGJIHDG_03565 2.1e-40 V ABC transporter, ATP-binding protein
HFGJIHDG_03566 9.5e-158 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HFGJIHDG_03567 3e-162 cysL K Transcriptional regulator
HFGJIHDG_03568 6.2e-158 MA20_14895 S Conserved hypothetical protein 698
HFGJIHDG_03569 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HFGJIHDG_03570 1.1e-146 ywfI C May function as heme-dependent peroxidase
HFGJIHDG_03571 1.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HFGJIHDG_03572 9.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
HFGJIHDG_03573 1e-207 bacE EGP Major facilitator Superfamily
HFGJIHDG_03574 2.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HFGJIHDG_03575 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFGJIHDG_03576 7.6e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HFGJIHDG_03577 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HFGJIHDG_03578 7.8e-222 ywfA EGP Major facilitator Superfamily
HFGJIHDG_03579 4.9e-205 tcaB EGP Major facilitator Superfamily
HFGJIHDG_03580 2.7e-258 lysP E amino acid
HFGJIHDG_03581 0.0 rocB E arginine degradation protein
HFGJIHDG_03582 8.6e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HFGJIHDG_03583 7.3e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HFGJIHDG_03584 1.9e-59
HFGJIHDG_03585 3e-86 spsL 5.1.3.13 M Spore Coat
HFGJIHDG_03586 1.2e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFGJIHDG_03587 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFGJIHDG_03588 1.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFGJIHDG_03589 5.6e-178 spsG M Spore Coat
HFGJIHDG_03590 2.6e-132 spsF M Spore Coat
HFGJIHDG_03591 2.4e-214 spsE 2.5.1.56 M acid synthase
HFGJIHDG_03592 1.2e-155 spsD 2.3.1.210 K Spore Coat
HFGJIHDG_03593 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
HFGJIHDG_03594 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
HFGJIHDG_03595 3.8e-142 spsA M Spore Coat
HFGJIHDG_03596 7.1e-60 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HFGJIHDG_03597 4.2e-46 ywdK S small membrane protein
HFGJIHDG_03598 5.4e-229 ywdJ F Xanthine uracil
HFGJIHDG_03599 4.7e-41 ywdI S Family of unknown function (DUF5327)
HFGJIHDG_03600 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFGJIHDG_03601 1.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
HFGJIHDG_03603 5.8e-88 ywdD
HFGJIHDG_03604 6.3e-57 pex K Transcriptional regulator PadR-like family
HFGJIHDG_03605 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFGJIHDG_03606 7.4e-20 ywdA
HFGJIHDG_03607 3.2e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
HFGJIHDG_03608 9.9e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFGJIHDG_03609 2.8e-151 sacT K transcriptional antiterminator
HFGJIHDG_03611 0.0 vpr O Belongs to the peptidase S8 family
HFGJIHDG_03612 1.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFGJIHDG_03613 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HFGJIHDG_03614 8e-208 rodA D Belongs to the SEDS family
HFGJIHDG_03615 1.7e-76 ysnE K acetyltransferase
HFGJIHDG_03616 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HFGJIHDG_03617 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HFGJIHDG_03618 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HFGJIHDG_03619 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HFGJIHDG_03620 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HFGJIHDG_03621 8.4e-27 ywzA S membrane
HFGJIHDG_03622 3.9e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HFGJIHDG_03623 5.1e-61 gtcA S GtrA-like protein
HFGJIHDG_03624 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
HFGJIHDG_03626 7.3e-129 H Methionine biosynthesis protein MetW
HFGJIHDG_03627 2.2e-130 S Streptomycin biosynthesis protein StrF
HFGJIHDG_03628 1.1e-109 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HFGJIHDG_03629 1.1e-242 ywbN P Dyp-type peroxidase family protein
HFGJIHDG_03630 6.6e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFGJIHDG_03631 3.1e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFGJIHDG_03632 8.2e-152 ywbI K Transcriptional regulator
HFGJIHDG_03633 4.2e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HFGJIHDG_03634 2.2e-109 ywbG M effector of murein hydrolase
HFGJIHDG_03635 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HFGJIHDG_03636 2.5e-138 mta K transcriptional
HFGJIHDG_03637 1e-223 ywbD 2.1.1.191 J Methyltransferase
HFGJIHDG_03638 7.6e-67 ywbC 4.4.1.5 E glyoxalase
HFGJIHDG_03639 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFGJIHDG_03640 1.1e-261 epr 3.4.21.62 O Belongs to the peptidase S8 family
HFGJIHDG_03641 4.1e-161 gspA M General stress
HFGJIHDG_03642 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HFGJIHDG_03643 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HFGJIHDG_03644 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
HFGJIHDG_03645 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_03646 4.8e-229 dltB M membrane protein involved in D-alanine export
HFGJIHDG_03647 1.6e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFGJIHDG_03648 3.1e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFGJIHDG_03649 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HFGJIHDG_03650 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HFGJIHDG_03651 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HFGJIHDG_03652 7.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFGJIHDG_03653 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HFGJIHDG_03654 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HFGJIHDG_03655 7.8e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HFGJIHDG_03656 2.8e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_03657 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFGJIHDG_03658 1.5e-166 cbrA3 P Periplasmic binding protein
HFGJIHDG_03659 1.7e-57 arsR K transcriptional
HFGJIHDG_03660 6.5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HFGJIHDG_03661 1.3e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HFGJIHDG_03662 8.6e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HFGJIHDG_03663 1.6e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFGJIHDG_03664 4e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFGJIHDG_03665 1.8e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HFGJIHDG_03666 1.8e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
HFGJIHDG_03667 2.1e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HFGJIHDG_03668 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HFGJIHDG_03669 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HFGJIHDG_03670 1e-251 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HFGJIHDG_03671 6.5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFGJIHDG_03672 8.5e-291 cydD V ATP-binding protein
HFGJIHDG_03673 2.4e-311 cydD V ATP-binding
HFGJIHDG_03674 1.1e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HFGJIHDG_03675 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
HFGJIHDG_03676 1e-214 cimH C COG3493 Na citrate symporter
HFGJIHDG_03677 9.6e-155 yxkH G Polysaccharide deacetylase
HFGJIHDG_03678 2.6e-205 msmK P Belongs to the ABC transporter superfamily
HFGJIHDG_03679 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HFGJIHDG_03680 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFGJIHDG_03681 3.8e-87 yxkC S Domain of unknown function (DUF4352)
HFGJIHDG_03682 2.4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFGJIHDG_03683 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HFGJIHDG_03686 2e-85 yxjI S LURP-one-related
HFGJIHDG_03687 1.8e-217 yxjG 2.1.1.14 E Methionine synthase
HFGJIHDG_03688 4.5e-155 rlmA 2.1.1.187 Q Methyltransferase domain
HFGJIHDG_03689 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFGJIHDG_03690 1.8e-71 T Domain of unknown function (DUF4163)
HFGJIHDG_03691 4.3e-49 yxiS
HFGJIHDG_03692 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HFGJIHDG_03693 1.4e-221 citH C Citrate transporter
HFGJIHDG_03694 2e-140 exoK GH16 M licheninase activity
HFGJIHDG_03695 1.4e-55 licT K transcriptional antiterminator
HFGJIHDG_03696 4.1e-21 licT K transcriptional antiterminator
HFGJIHDG_03697 3.7e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
HFGJIHDG_03698 3.4e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HFGJIHDG_03701 1.2e-61 S SMI1-KNR4 cell-wall
HFGJIHDG_03702 1.6e-48 yxiI S Protein of unknown function (DUF2716)
HFGJIHDG_03703 4.2e-22
HFGJIHDG_03704 1.1e-14 S YxiJ-like protein
HFGJIHDG_03706 5.2e-78
HFGJIHDG_03707 2.8e-32
HFGJIHDG_03711 8.6e-69 yxiG
HFGJIHDG_03712 1.4e-45 yxxG
HFGJIHDG_03713 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
HFGJIHDG_03714 6.1e-147 yxxF EG EamA-like transporter family
HFGJIHDG_03715 1.8e-72 yxiE T Belongs to the universal stress protein A family
HFGJIHDG_03716 0.0 L HKD family nuclease
HFGJIHDG_03717 5.5e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HFGJIHDG_03718 2e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HFGJIHDG_03719 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HFGJIHDG_03720 1.1e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
HFGJIHDG_03721 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HFGJIHDG_03722 1.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HFGJIHDG_03723 4.7e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HFGJIHDG_03724 4.4e-253 lysP E amino acid
HFGJIHDG_03725 2.5e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HFGJIHDG_03726 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFGJIHDG_03727 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFGJIHDG_03728 9.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HFGJIHDG_03729 2.6e-149 yidA S hydrolases of the HAD superfamily
HFGJIHDG_03733 8.4e-23 yxeD
HFGJIHDG_03734 1.3e-34
HFGJIHDG_03735 4.1e-178 fhuD P Periplasmic binding protein
HFGJIHDG_03736 1.3e-57 yxeA S Protein of unknown function (DUF1093)
HFGJIHDG_03737 0.0 yxdM V ABC transporter (permease)
HFGJIHDG_03738 3.6e-140 yxdL V ABC transporter, ATP-binding protein
HFGJIHDG_03739 3.5e-177 T PhoQ Sensor
HFGJIHDG_03740 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_03741 1.8e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HFGJIHDG_03742 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HFGJIHDG_03743 3.3e-166 iolH G Xylose isomerase-like TIM barrel
HFGJIHDG_03744 5.8e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HFGJIHDG_03745 5.1e-232 iolF EGP Major facilitator Superfamily
HFGJIHDG_03746 2e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HFGJIHDG_03747 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HFGJIHDG_03748 3.8e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HFGJIHDG_03749 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HFGJIHDG_03750 1.8e-278 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFGJIHDG_03751 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
HFGJIHDG_03752 1.2e-174 iolS C Aldo keto reductase
HFGJIHDG_03753 1.9e-245 csbC EGP Major facilitator Superfamily
HFGJIHDG_03754 0.0 htpG O Molecular chaperone. Has ATPase activity
HFGJIHDG_03756 4.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
HFGJIHDG_03757 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFGJIHDG_03758 1.7e-199 desK 2.7.13.3 T Histidine kinase
HFGJIHDG_03759 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HFGJIHDG_03760 1.2e-213 yxbF K Bacterial regulatory proteins, tetR family
HFGJIHDG_03761 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HFGJIHDG_03762 2.8e-142 S PQQ-like domain
HFGJIHDG_03763 1e-64 S Family of unknown function (DUF5391)
HFGJIHDG_03764 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
HFGJIHDG_03765 1.9e-201 EGP Major facilitator Superfamily
HFGJIHDG_03766 7.6e-74 yxaI S membrane protein domain
HFGJIHDG_03767 3.2e-124 E Ring-cleavage extradiol dioxygenase
HFGJIHDG_03768 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HFGJIHDG_03769 2.3e-287 ahpF O Alkyl hydroperoxide reductase
HFGJIHDG_03770 7.9e-244 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HFGJIHDG_03771 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HFGJIHDG_03772 5.9e-82 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HFGJIHDG_03773 4.7e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HFGJIHDG_03774 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HFGJIHDG_03775 7.4e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HFGJIHDG_03776 6.9e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HFGJIHDG_03777 2e-173 S Fusaric acid resistance protein-like
HFGJIHDG_03778 6.8e-139 L AAA domain
HFGJIHDG_03779 3.2e-157 L AAA domain
HFGJIHDG_03780 1.1e-244 L Uncharacterized conserved protein (DUF2075)
HFGJIHDG_03781 6.8e-42 S MazG-like family
HFGJIHDG_03782 1.8e-39 L COG2963 Transposase and inactivated derivatives
HFGJIHDG_03783 9.7e-134 L Molecular Function DNA binding, Biological Process DNA recombination
HFGJIHDG_03784 9.9e-200 3.6.4.12 KL HELICc2
HFGJIHDG_03785 3e-13 tnp L transposase activity
HFGJIHDG_03786 7.5e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFGJIHDG_03787 7.9e-08 S YyzF-like protein
HFGJIHDG_03789 6.2e-213 yycP
HFGJIHDG_03790 4.5e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HFGJIHDG_03791 3.3e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
HFGJIHDG_03792 9e-86 yycN 2.3.1.128 K Acetyltransferase
HFGJIHDG_03794 1.1e-198 S Histidine kinase
HFGJIHDG_03795 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HFGJIHDG_03796 1.1e-256 rocE E amino acid
HFGJIHDG_03797 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HFGJIHDG_03798 4.2e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HFGJIHDG_03799 2.2e-42 sdpR K transcriptional
HFGJIHDG_03800 7.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HFGJIHDG_03801 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
HFGJIHDG_03802 1.8e-303 S ABC transporter
HFGJIHDG_03803 7.7e-195 S Major Facilitator Superfamily
HFGJIHDG_03804 8e-257
HFGJIHDG_03805 3.9e-187 2.7.7.73, 2.7.7.80 H ThiF family
HFGJIHDG_03806 2.5e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HFGJIHDG_03807 2.1e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_03808 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFGJIHDG_03809 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HFGJIHDG_03810 1.1e-150 yycI S protein conserved in bacteria
HFGJIHDG_03811 2.5e-261 yycH S protein conserved in bacteria
HFGJIHDG_03812 0.0 vicK 2.7.13.3 T Histidine kinase
HFGJIHDG_03813 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFGJIHDG_03818 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFGJIHDG_03819 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFGJIHDG_03820 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HFGJIHDG_03821 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HFGJIHDG_03823 4.6e-17 yycC K YycC-like protein
HFGJIHDG_03824 1.4e-234 M Glycosyltransferase Family 4
HFGJIHDG_03825 6.9e-203 S Ecdysteroid kinase
HFGJIHDG_03826 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
HFGJIHDG_03827 5.1e-243 M Glycosyltransferase Family 4
HFGJIHDG_03828 2.7e-120 S GlcNAc-PI de-N-acetylase
HFGJIHDG_03829 8.2e-102 KLT COG0515 Serine threonine protein kinase
HFGJIHDG_03830 4.9e-73 rplI J binds to the 23S rRNA
HFGJIHDG_03831 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HFGJIHDG_03832 2.4e-159 yybS S membrane
HFGJIHDG_03834 6.1e-83 cotF M Spore coat protein
HFGJIHDG_03835 8.2e-66 ydeP3 K Transcriptional regulator
HFGJIHDG_03836 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HFGJIHDG_03837 1.2e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HFGJIHDG_03838 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
HFGJIHDG_03839 1.5e-310 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HFGJIHDG_03840 2.2e-114 K FCD domain
HFGJIHDG_03841 5.2e-71 dinB S PFAM DinB family protein
HFGJIHDG_03842 5.4e-159 G Major Facilitator Superfamily
HFGJIHDG_03843 2.2e-55 ypaA S Protein of unknown function (DUF1304)
HFGJIHDG_03844 1.6e-114 drgA C nitroreductase
HFGJIHDG_03845 4.1e-69 ydgJ K Winged helix DNA-binding domain
HFGJIHDG_03846 1e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HFGJIHDG_03847 1.6e-76 yybA 2.3.1.57 K transcriptional
HFGJIHDG_03848 8.9e-61 lysR K LysR substrate binding domain
HFGJIHDG_03849 2.8e-91
HFGJIHDG_03850 6.4e-162 eaeH M Domain of Unknown Function (DUF1259)
HFGJIHDG_03851 1.7e-64 4.1.1.44 S Carboxymuconolactone decarboxylase family
HFGJIHDG_03852 2.5e-161 K Transcriptional regulator
HFGJIHDG_03853 3.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HFGJIHDG_03854 2.7e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFGJIHDG_03855 3.6e-131 ydfC EG EamA-like transporter family
HFGJIHDG_03856 4.3e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFGJIHDG_03857 3.3e-78 K Transcriptional regulator
HFGJIHDG_03858 7.6e-14 yvaO K Transcriptional
HFGJIHDG_03859 2.1e-40 qacC U Small Multidrug Resistance protein
HFGJIHDG_03860 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HFGJIHDG_03861 9.5e-161 yyaK S CAAX protease self-immunity
HFGJIHDG_03862 4.2e-97 ydjK G Sugar (and other) transporter
HFGJIHDG_03863 8e-120 ydjK G Sugar (and other) transporter
HFGJIHDG_03864 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFGJIHDG_03865 1.2e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HFGJIHDG_03866 7.8e-140 xth 3.1.11.2 L exodeoxyribonuclease III
HFGJIHDG_03867 2.7e-97 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFGJIHDG_03868 4.8e-105 adaA 3.2.2.21 K Transcriptional regulator
HFGJIHDG_03869 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFGJIHDG_03870 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFGJIHDG_03871 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HFGJIHDG_03872 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFGJIHDG_03873 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFGJIHDG_03874 2.3e-33 yyzM S protein conserved in bacteria
HFGJIHDG_03875 2.4e-176 yyaD S Membrane
HFGJIHDG_03876 1.1e-40 4.2.1.103 K FR47-like protein
HFGJIHDG_03877 6.2e-111 yyaC S Sporulation protein YyaC
HFGJIHDG_03878 1.5e-147 spo0J K Belongs to the ParB family
HFGJIHDG_03879 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
HFGJIHDG_03880 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HFGJIHDG_03881 7.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HFGJIHDG_03882 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFGJIHDG_03883 2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFGJIHDG_03884 1.3e-108 jag S single-stranded nucleic acid binding R3H
HFGJIHDG_03885 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFGJIHDG_03886 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFGJIHDG_03888 1.1e-86 S Tetratricopeptide repeat
HFGJIHDG_03889 5.3e-184 L Replication protein
HFGJIHDG_03892 3e-72 sipT 3.4.21.89 U Signal peptidase, peptidase S26
HFGJIHDG_03893 8.7e-156 pre D plasmid recombination enzyme
HFGJIHDG_03894 6.8e-73 K Transcriptional regulator

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)