ORF_ID e_value Gene_name EC_number CAZy COGs Description
HNKEEIEE_00001 1.6e-282 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HNKEEIEE_00002 1e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HNKEEIEE_00003 9.8e-55 yaaQ S protein conserved in bacteria
HNKEEIEE_00004 1.5e-71 yaaR S protein conserved in bacteria
HNKEEIEE_00005 2.8e-185 holB 2.7.7.7 L DNA polymerase III
HNKEEIEE_00006 1.7e-148 yaaT S stage 0 sporulation protein
HNKEEIEE_00007 3.3e-61 yabA L Involved in initiation control of chromosome replication
HNKEEIEE_00008 2.7e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
HNKEEIEE_00009 7.1e-49 yazA L endonuclease containing a URI domain
HNKEEIEE_00010 2.2e-162 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNKEEIEE_00011 4.8e-55 abrB K COG2002 Regulators of stationary sporulation gene expression
HNKEEIEE_00012 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNKEEIEE_00013 8e-148 tatD L hydrolase, TatD
HNKEEIEE_00014 1.1e-104 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNKEEIEE_00015 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HNKEEIEE_00016 5.8e-163 yabG S peptidase
HNKEEIEE_00017 2.4e-37 veg S protein conserved in bacteria
HNKEEIEE_00018 1.9e-26 sspF S DNA topological change
HNKEEIEE_00019 7.3e-158 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HNKEEIEE_00020 1.3e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HNKEEIEE_00021 1.2e-61 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HNKEEIEE_00022 5.1e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HNKEEIEE_00023 2.3e-243 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HNKEEIEE_00024 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNKEEIEE_00025 2e-112 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HNKEEIEE_00026 2.1e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HNKEEIEE_00027 5.7e-38 yabK S Peptide ABC transporter permease
HNKEEIEE_00028 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNKEEIEE_00029 2.1e-91 spoVT K stage V sporulation protein
HNKEEIEE_00030 2.4e-276 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNKEEIEE_00031 4e-190 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HNKEEIEE_00032 6.9e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HNKEEIEE_00033 3e-50 yabP S Sporulation protein YabP
HNKEEIEE_00034 8e-106 yabQ S spore cortex biosynthesis protein
HNKEEIEE_00035 1.9e-60 divIC D Septum formation initiator
HNKEEIEE_00036 4.8e-54 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HNKEEIEE_00038 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HNKEEIEE_00039 8.7e-120 yabS S protein containing a von Willebrand factor type A (vWA) domain
HNKEEIEE_00040 2.8e-166 KLT serine threonine protein kinase
HNKEEIEE_00041 4e-278 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HNKEEIEE_00042 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HNKEEIEE_00043 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNKEEIEE_00044 1.7e-159 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HNKEEIEE_00045 3e-159 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HNKEEIEE_00046 3.4e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HNKEEIEE_00047 4.4e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HNKEEIEE_00048 3.2e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HNKEEIEE_00049 1.1e-97 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HNKEEIEE_00052 5.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HNKEEIEE_00053 2.3e-72 K sequence-specific DNA binding
HNKEEIEE_00054 1.3e-116 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
HNKEEIEE_00055 1.6e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNKEEIEE_00056 3.2e-222 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HNKEEIEE_00057 3.1e-153 K RpiR family transcriptional regulator
HNKEEIEE_00058 1.1e-143 ypuA S Secreted protein
HNKEEIEE_00059 4.7e-107
HNKEEIEE_00060 3.1e-69 S response to pH
HNKEEIEE_00061 1.2e-106 che
HNKEEIEE_00062 5.2e-292 K helix_turn_helix, Lux Regulon
HNKEEIEE_00063 4.6e-89 S Protein of unknown function (DUF1073)
HNKEEIEE_00064 2.9e-61 S Phage Mu protein F like protein
HNKEEIEE_00065 1.9e-130 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HNKEEIEE_00066 2.7e-252 ugpB G Glycerol-3-phosphate ABC transporter substrate-binding protein
HNKEEIEE_00067 2.3e-137 ugpE P Glycerol-3-phosphate ABC transporter permease
HNKEEIEE_00068 1.1e-164 ugpA G ABC transporter (permease)
HNKEEIEE_00069 2.5e-203 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
HNKEEIEE_00070 3.3e-98 K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HNKEEIEE_00071 5.3e-121 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HNKEEIEE_00072 2.1e-246
HNKEEIEE_00073 3.7e-154 T STAS domain
HNKEEIEE_00074 1.8e-243 braB E Component of the transport system for branched-chain amino acids
HNKEEIEE_00075 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HNKEEIEE_00076 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HNKEEIEE_00077 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
HNKEEIEE_00078 4.7e-196 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HNKEEIEE_00079 3.4e-283 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HNKEEIEE_00080 3.4e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HNKEEIEE_00081 8e-271 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HNKEEIEE_00082 7.8e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HNKEEIEE_00083 3.7e-188 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNKEEIEE_00084 2.7e-221 2.6.1.9 S HAD-hyrolase-like
HNKEEIEE_00085 1.5e-178 S Phosphotransferase system, EIIC
HNKEEIEE_00086 1.5e-302 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNKEEIEE_00087 1.4e-220 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HNKEEIEE_00088 3.8e-184 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNKEEIEE_00089 8.3e-250 mcpA NT chemotaxis protein
HNKEEIEE_00091 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HNKEEIEE_00092 1.3e-48 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
HNKEEIEE_00093 4.6e-263 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HNKEEIEE_00094 7.4e-109 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HNKEEIEE_00095 1.4e-184 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HNKEEIEE_00096 1.7e-257 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
HNKEEIEE_00097 2.8e-224 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HNKEEIEE_00099 2.1e-140 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HNKEEIEE_00100 5e-24 yfhD S YfhD-like protein
HNKEEIEE_00102 9.6e-144 recX 2.4.1.337 GT4 S Modulates RecA activity
HNKEEIEE_00103 2.8e-51 yfhH S Protein of unknown function (DUF1811)
HNKEEIEE_00104 4.9e-20 sspK S reproduction
HNKEEIEE_00105 1.6e-182 yfhP S membrane-bound metal-dependent
HNKEEIEE_00106 8.2e-199 mutY L A G-specific
HNKEEIEE_00107 5.6e-288 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HNKEEIEE_00108 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HNKEEIEE_00109 3.8e-165 gltC K Transcriptional regulator
HNKEEIEE_00110 7.7e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNKEEIEE_00111 1.7e-08 sspE S Small, acid-soluble spore protein, gamma-type
HNKEEIEE_00112 1.3e-35 ygaB S YgaB-like protein
HNKEEIEE_00113 8.2e-104 ygaC J Belongs to the UPF0374 family
HNKEEIEE_00114 0.0 ygaD V ABC transporter
HNKEEIEE_00115 3.3e-208 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HNKEEIEE_00116 1.4e-151 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HNKEEIEE_00117 1.6e-250 sacX 2.7.1.201, 2.7.1.211 G phosphotransferase system
HNKEEIEE_00118 4.7e-149 K transcriptional
HNKEEIEE_00119 5.4e-187 ygaE S Membrane
HNKEEIEE_00120 1.1e-38 yqhV S Protein of unknown function (DUF2619)
HNKEEIEE_00121 3.9e-63
HNKEEIEE_00122 1.6e-225 yitG EGP Major facilitator Superfamily
HNKEEIEE_00123 5.1e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNKEEIEE_00124 3.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HNKEEIEE_00125 4e-139 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HNKEEIEE_00126 2.7e-164 ssuA P ABC transporter substrate-binding protein
HNKEEIEE_00127 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HNKEEIEE_00128 3.4e-65 P Ion transport
HNKEEIEE_00130 3.4e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
HNKEEIEE_00131 9.8e-82 perR P Belongs to the Fur family
HNKEEIEE_00133 2e-88 iprA K Transcriptional regulator
HNKEEIEE_00134 4.5e-163 alsR K Transcriptional regulator
HNKEEIEE_00135 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HNKEEIEE_00136 1e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HNKEEIEE_00137 7.8e-58 ygzB S UPF0295 protein
HNKEEIEE_00138 2.3e-164 ygxA S Nucleotidyltransferase-like
HNKEEIEE_00139 1.5e-43 ylaN S Belongs to the UPF0358 family
HNKEEIEE_00140 1.8e-218 ftsW D Belongs to the SEDS family
HNKEEIEE_00141 5e-176 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HNKEEIEE_00142 5.1e-162 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HNKEEIEE_00143 4.4e-197 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HNKEEIEE_00144 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNKEEIEE_00145 2.1e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HNKEEIEE_00146 1.2e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HNKEEIEE_00147 1.3e-168 ctaG S cytochrome c oxidase
HNKEEIEE_00148 9.6e-64 ylbA S YugN-like family
HNKEEIEE_00149 3e-167 ylbC S protein with SCP PR1 domains
HNKEEIEE_00150 1e-84 yiiD Q protein, possibly involved in aromatic compounds catabolism
HNKEEIEE_00151 4.4e-70 ylbD S Putative coat protein
HNKEEIEE_00152 7.9e-38 ylbE S YlbE-like protein
HNKEEIEE_00153 1.1e-65
HNKEEIEE_00154 2.8e-73 ylbF S Belongs to the UPF0342 family
HNKEEIEE_00155 4.1e-45 ylbG S UPF0298 protein
HNKEEIEE_00156 7.7e-67 S Methylthioribose kinase
HNKEEIEE_00157 2.8e-108 rsmD 2.1.1.171 L Methyltransferase
HNKEEIEE_00158 1.7e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HNKEEIEE_00159 1.7e-221 ylbJ S Sporulation integral membrane protein YlbJ
HNKEEIEE_00160 5.3e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
HNKEEIEE_00161 1e-193 ylbL T Belongs to the peptidase S16 family
HNKEEIEE_00162 5.2e-226 ylbM S Belongs to the UPF0348 family
HNKEEIEE_00163 1.2e-93 yceD S metal-binding, possibly nucleic acid-binding protein
HNKEEIEE_00164 1.1e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HNKEEIEE_00165 1.5e-81 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HNKEEIEE_00166 2.3e-92 ylbP K n-acetyltransferase
HNKEEIEE_00167 1.1e-158 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNKEEIEE_00168 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HNKEEIEE_00170 2e-79 mraZ K Belongs to the MraZ family
HNKEEIEE_00171 7e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HNKEEIEE_00172 1.7e-39 ftsL D Essential cell division protein
HNKEEIEE_00173 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HNKEEIEE_00174 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HNKEEIEE_00175 4.8e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNKEEIEE_00176 1.7e-78 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HNKEEIEE_00177 6.4e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNKEEIEE_00178 5.1e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNKEEIEE_00179 1.2e-189 spoVE D Belongs to the SEDS family
HNKEEIEE_00180 7.7e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNKEEIEE_00181 4e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HNKEEIEE_00182 1.6e-217 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HNKEEIEE_00183 3.6e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNKEEIEE_00184 7.3e-164 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HNKEEIEE_00185 3.5e-113 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNKEEIEE_00186 6.8e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNKEEIEE_00189 1.2e-199 M1-161 T HD domain
HNKEEIEE_00190 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNKEEIEE_00191 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNKEEIEE_00192 6.2e-10 yaaB S Domain of unknown function (DUF370)
HNKEEIEE_00193 3.5e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HNKEEIEE_00194 2.4e-33 yaaA S S4 domain
HNKEEIEE_00195 7e-209 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HNKEEIEE_00196 9e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HNKEEIEE_00197 4.2e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HNKEEIEE_00198 3.2e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNKEEIEE_00199 3.4e-109 jag S single-stranded nucleic acid binding R3H
HNKEEIEE_00200 6.2e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HNKEEIEE_00201 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HNKEEIEE_00202 9.7e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HNKEEIEE_00203 5.9e-152 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HNKEEIEE_00204 6.9e-136 soj D COG1192 ATPases involved in chromosome partitioning
HNKEEIEE_00205 1.1e-150 spo0J K Belongs to the ParB family
HNKEEIEE_00206 2.7e-118 ydfK S Protein of unknown function (DUF554)
HNKEEIEE_00207 1.5e-112 yyaC S Sporulation protein YyaC
HNKEEIEE_00208 2.5e-156 ykuT M Mechanosensitive ion channel
HNKEEIEE_00209 1.1e-32 yyzM S protein conserved in bacteria
HNKEEIEE_00210 1e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HNKEEIEE_00211 3.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HNKEEIEE_00212 4.7e-117 ribE 2.5.1.9 H Riboflavin synthase
HNKEEIEE_00213 2.1e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HNKEEIEE_00214 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HNKEEIEE_00215 1.5e-43 ylmC S sporulation protein
HNKEEIEE_00216 5.3e-74 yocH CBM50 M 3D domain
HNKEEIEE_00217 3e-161 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HNKEEIEE_00218 2e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HNKEEIEE_00219 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HNKEEIEE_00220 1.4e-38 yggT S membrane
HNKEEIEE_00221 9.8e-146 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HNKEEIEE_00222 3.3e-65 divIVA D Cell division initiation protein
HNKEEIEE_00223 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNKEEIEE_00225 1.3e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HNKEEIEE_00226 4.6e-179 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HNKEEIEE_00227 8.7e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNKEEIEE_00228 1.6e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HNKEEIEE_00229 5.4e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HNKEEIEE_00230 3.4e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HNKEEIEE_00231 0.0 carB 6.3.5.5 F Belongs to the CarB family
HNKEEIEE_00232 1.2e-140 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HNKEEIEE_00233 4e-181 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HNKEEIEE_00234 1.1e-122 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HNKEEIEE_00235 9.9e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HNKEEIEE_00236 2.7e-171 S Nuclease-related domain
HNKEEIEE_00237 7.2e-211 L Transposase IS4 family protein
HNKEEIEE_00238 7.1e-39 3.2.2.21 K sequence-specific DNA binding
HNKEEIEE_00239 2.7e-193 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HNKEEIEE_00240 3.8e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HNKEEIEE_00242 5e-35 S double-stranded DNA endodeoxyribonuclease activity
HNKEEIEE_00243 1.8e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNKEEIEE_00244 1.7e-246 EGP Major facilitator Superfamily
HNKEEIEE_00245 1.4e-222 lmrB EGP the major facilitator superfamily
HNKEEIEE_00246 5.1e-96 yxaF_1 K Transcriptional regulator
HNKEEIEE_00247 1e-111 atsK 1.14.11.17 Q Taurine catabolism dioxygenase TauD, TfdA family
HNKEEIEE_00248 1.3e-194 S AI-2E family transporter
HNKEEIEE_00249 3.3e-50 S FAD binding domain
HNKEEIEE_00250 4e-167 yihP G MFS/sugar transport protein
HNKEEIEE_00251 1.9e-23 L Transposase DDE domain
HNKEEIEE_00252 3.6e-48 ykvR S Protein of unknown function (DUF3219)
HNKEEIEE_00253 3.7e-174 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNKEEIEE_00255 1.1e-152 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNKEEIEE_00256 3.8e-68 2.1.1.163, 2.1.1.201 Q Methyltransferase type 11
HNKEEIEE_00257 6.5e-90 O Methyltransferase
HNKEEIEE_00258 6.6e-27
HNKEEIEE_00259 2.8e-51 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNKEEIEE_00260 2.4e-36 XK27_07760 S COG4980 Gas vesicle protein
HNKEEIEE_00261 4.3e-192 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HNKEEIEE_00262 1.7e-182 ccpA K catabolite control protein A
HNKEEIEE_00263 2e-232 acuC BQ histone deacetylase
HNKEEIEE_00264 1.1e-118 acuB S Acetoin utilization protein AcuB
HNKEEIEE_00265 1.2e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HNKEEIEE_00266 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HNKEEIEE_00267 9.4e-133 modA P Molybdenum ABC transporter
HNKEEIEE_00268 1e-120 P COG4149 ABC-type molybdate transport system, permease component
HNKEEIEE_00269 9.5e-132 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
HNKEEIEE_00270 3.8e-204 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HNKEEIEE_00271 1.4e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HNKEEIEE_00272 6.6e-122 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HNKEEIEE_00273 1.8e-234 moeA 2.10.1.1 H molybdopterin
HNKEEIEE_00274 1.3e-87 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HNKEEIEE_00275 1.2e-79 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HNKEEIEE_00276 1.1e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HNKEEIEE_00277 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HNKEEIEE_00278 1.8e-192 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HNKEEIEE_00279 2e-89 yrhD S Protein of unknown function (DUF1641)
HNKEEIEE_00280 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HNKEEIEE_00281 3.3e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HNKEEIEE_00282 1.1e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HNKEEIEE_00283 7e-256 prdR KT Transcriptional regulator
HNKEEIEE_00284 7.8e-296 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HNKEEIEE_00285 2.4e-181 putA E Proline dehydrogenase
HNKEEIEE_00286 2e-126
HNKEEIEE_00287 1.3e-145
HNKEEIEE_00288 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HNKEEIEE_00289 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HNKEEIEE_00290 1.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
HNKEEIEE_00291 7.8e-117 yttP K Transcriptional regulator
HNKEEIEE_00292 5.9e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HNKEEIEE_00293 5.6e-214 iscS2 2.8.1.7 E Cysteine desulfurase
HNKEEIEE_00294 1.9e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNKEEIEE_00295 1.4e-27 sspB S spore protein
HNKEEIEE_00296 2.2e-311 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HNKEEIEE_00297 3.1e-184 sppA OU signal peptide peptidase SppA
HNKEEIEE_00298 4.1e-87 yteJ S RDD family
HNKEEIEE_00299 6.1e-120 ytfI S Protein of unknown function (DUF2953)
HNKEEIEE_00300 5.8e-69 ytfJ S Sporulation protein YtfJ
HNKEEIEE_00301 9.9e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HNKEEIEE_00302 2.2e-174 ytxK 2.1.1.72 L DNA methylase
HNKEEIEE_00303 9.2e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNKEEIEE_00304 3.1e-150 S EcsC protein family
HNKEEIEE_00305 3.1e-78 uspA T Belongs to the universal stress protein A family
HNKEEIEE_00306 2.3e-196 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HNKEEIEE_00307 2.1e-178 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HNKEEIEE_00308 1.1e-129 ytkL S Belongs to the UPF0173 family
HNKEEIEE_00309 1e-240 ytoI K transcriptional regulator containing CBS domains
HNKEEIEE_00310 5.4e-39 ytpI S YtpI-like protein
HNKEEIEE_00311 7.6e-177 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HNKEEIEE_00312 4.2e-89 ytrI
HNKEEIEE_00313 1.6e-41 ytrH S Sporulation protein YtrH
HNKEEIEE_00314 0.0 dnaE 2.7.7.7 L DNA polymerase
HNKEEIEE_00315 9.8e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HNKEEIEE_00316 6.2e-165 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HNKEEIEE_00317 1.1e-178 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HNKEEIEE_00318 3.2e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HNKEEIEE_00319 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HNKEEIEE_00320 5e-159 ytvI S sporulation integral membrane protein YtvI
HNKEEIEE_00321 1e-73 yeaL S Membrane
HNKEEIEE_00322 2.6e-58 S YqcI/YcgG family
HNKEEIEE_00323 5.6e-98 L Integrase
HNKEEIEE_00324 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HNKEEIEE_00325 4.2e-62 K transcriptional
HNKEEIEE_00326 4.1e-164 mleR K LysR substrate binding domain
HNKEEIEE_00327 3.6e-90 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
HNKEEIEE_00328 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HNKEEIEE_00329 6.8e-206 U protein localization to endoplasmic reticulum
HNKEEIEE_00333 6.8e-34 ydhM 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HNKEEIEE_00334 1.5e-207 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNKEEIEE_00335 4.4e-36 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
HNKEEIEE_00336 1.9e-240 ydhP 3.2.1.21, 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HNKEEIEE_00337 1.7e-91 ydhQ K UTRA
HNKEEIEE_00338 1.7e-159 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HNKEEIEE_00339 8.6e-10 S PD-(D/E)XK nuclease family transposase
HNKEEIEE_00340 1.4e-128 IQ Enoyl-(Acyl carrier protein) reductase
HNKEEIEE_00341 9.8e-166 yhaQ S ABC transporter, ATP-binding protein
HNKEEIEE_00342 2.6e-209 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HNKEEIEE_00343 5.6e-258 pepC 3.4.22.40 E Papain family cysteine protease
HNKEEIEE_00344 0.0 pepF2 E COG1164 Oligoendopeptidase F
HNKEEIEE_00345 1.6e-33 ykuS S Belongs to the UPF0180 family
HNKEEIEE_00346 1e-20
HNKEEIEE_00347 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
HNKEEIEE_00348 2.8e-91 ywrA P COG2059 Chromate transport protein ChrA
HNKEEIEE_00349 6.3e-100 chrA P COG2059 Chromate transport protein ChrA
HNKEEIEE_00350 3.6e-82 ywrC K Transcriptional regulator
HNKEEIEE_00351 1.9e-37 L Belongs to the 'phage' integrase family
HNKEEIEE_00353 1.6e-144 pocR K Sensory domain found in PocR
HNKEEIEE_00354 4.4e-225 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNKEEIEE_00355 8.5e-212 yxjG 2.1.1.14 E Methionine synthase
HNKEEIEE_00356 7e-113 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HNKEEIEE_00357 1.3e-260 proP EGP Transporter
HNKEEIEE_00358 5.5e-98 K Glycerol-3-phosphate responsive antiterminator
HNKEEIEE_00359 5.6e-116 sapB S MgtC SapB transporter
HNKEEIEE_00360 1e-156 araL 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HNKEEIEE_00361 1.3e-150 G myo-inosose-2 dehydratase activity
HNKEEIEE_00362 6.1e-252 EGP Sugar (and other) transporter
HNKEEIEE_00363 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
HNKEEIEE_00364 1.1e-158 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HNKEEIEE_00365 2e-128 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HNKEEIEE_00366 9.1e-107 yocH CBM50 M COG1388 FOG LysM repeat
HNKEEIEE_00367 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNKEEIEE_00368 5.9e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HNKEEIEE_00369 1.9e-175 corA P Mg2 transporter protein
HNKEEIEE_00370 3.3e-69 S CHY zinc finger
HNKEEIEE_00371 1.3e-212 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HNKEEIEE_00372 8.1e-111 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HNKEEIEE_00373 2.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HNKEEIEE_00374 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HNKEEIEE_00375 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HNKEEIEE_00376 1.1e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HNKEEIEE_00377 6.6e-139 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HNKEEIEE_00378 1e-119 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HNKEEIEE_00379 5.9e-41 yedF O Belongs to the sulfur carrier protein TusA family
HNKEEIEE_00380 4.9e-240 yedE S Sulphur transport
HNKEEIEE_00381 3.9e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
HNKEEIEE_00382 5.4e-23 S Short C-terminal domain
HNKEEIEE_00383 6.6e-105 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HNKEEIEE_00384 1.2e-116 S TPM domain
HNKEEIEE_00385 7.2e-77 lemA S LemA family
HNKEEIEE_00387 4.3e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNKEEIEE_00388 1.2e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNKEEIEE_00389 9.1e-119 S VIT family
HNKEEIEE_00390 3.9e-154 czcD P COG1230 Co Zn Cd efflux system component
HNKEEIEE_00391 2.7e-14 sda S Sporulation inhibitor A
HNKEEIEE_00392 3e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNKEEIEE_00393 2.1e-126 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNKEEIEE_00394 4.8e-293 ahpF O Alkyl hydroperoxide reductase
HNKEEIEE_00395 1.4e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HNKEEIEE_00397 1.7e-10 S YrhC-like protein
HNKEEIEE_00398 1.1e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HNKEEIEE_00399 3.4e-29 yrzA S Protein of unknown function (DUF2536)
HNKEEIEE_00400 7.4e-56 yrrS S Protein of unknown function (DUF1510)
HNKEEIEE_00401 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNKEEIEE_00402 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HNKEEIEE_00403 4.6e-117 yrrM 2.1.1.104 S O-methyltransferase
HNKEEIEE_00404 8.8e-201 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNKEEIEE_00405 1.5e-41 yrzB S Belongs to the UPF0473 family
HNKEEIEE_00406 6.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HNKEEIEE_00407 5.8e-45 yrzL S Belongs to the UPF0297 family
HNKEEIEE_00408 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HNKEEIEE_00409 1.7e-175 yrrI S AI-2E family transporter
HNKEEIEE_00411 1.8e-29 yrzR
HNKEEIEE_00412 1.6e-73 yndM S Protein of unknown function (DUF2512)
HNKEEIEE_00413 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HNKEEIEE_00414 1.3e-125 S COG0457 FOG TPR repeat
HNKEEIEE_00415 9.8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HNKEEIEE_00416 6.9e-209 iscS 2.8.1.7 E Cysteine desulfurase
HNKEEIEE_00417 3.2e-72 cymR K Transcriptional regulator
HNKEEIEE_00418 4.5e-230 L PFAM Transposase, IS116 IS110 IS902
HNKEEIEE_00419 8.8e-136 IQ Short-chain dehydrogenase reductase sdr
HNKEEIEE_00420 2.8e-238 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HNKEEIEE_00421 1.2e-135 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HNKEEIEE_00422 2.2e-163 ybaS 1.1.1.58 S Na -dependent transporter
HNKEEIEE_00424 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HNKEEIEE_00425 5.9e-249 hisS 6.1.1.21 J histidyl-tRNA synthetase
HNKEEIEE_00427 2.2e-34 C acyl-CoA transferases carnitine dehydratase
HNKEEIEE_00428 6.5e-182 yfmJ S N-terminal domain of oxidoreductase
HNKEEIEE_00429 3.7e-56 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
HNKEEIEE_00430 2.1e-244 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HNKEEIEE_00431 4.8e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HNKEEIEE_00432 2.1e-80 K Acetyltransferase (GNAT) domain
HNKEEIEE_00433 7.2e-98 O HI0933-like protein
HNKEEIEE_00434 2.3e-44 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HNKEEIEE_00435 6.5e-173 oppD P Belongs to the ABC transporter superfamily
HNKEEIEE_00436 7e-175 oppF P Belongs to the ABC transporter superfamily
HNKEEIEE_00437 3.4e-172 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNKEEIEE_00438 2.2e-133 oppC EP binding-protein-dependent transport systems inner membrane component
HNKEEIEE_00439 1.3e-265 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
HNKEEIEE_00440 2.1e-66 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
HNKEEIEE_00441 2.9e-147 yjbA S Belongs to the UPF0736 family
HNKEEIEE_00442 1e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HNKEEIEE_00443 1.3e-49 S Domain of unknown function (DUF3899)
HNKEEIEE_00444 0.0 dppE_1 E ABC transporter substrate-binding protein
HNKEEIEE_00445 5.8e-153 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNKEEIEE_00446 1.4e-184 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNKEEIEE_00447 1.1e-197 oppD P Belongs to the ABC transporter superfamily
HNKEEIEE_00448 3e-173 oppF E Belongs to the ABC transporter superfamily
HNKEEIEE_00449 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HNKEEIEE_00450 2.7e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HNKEEIEE_00451 2.7e-227 yjbF S Competence protein
HNKEEIEE_00452 1.2e-233 pepF E oligoendopeptidase F
HNKEEIEE_00453 2.1e-91 pepF E oligoendopeptidase F
HNKEEIEE_00455 9.1e-161 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HNKEEIEE_00456 5.2e-74 yjbI S COG2346 Truncated hemoglobins
HNKEEIEE_00457 2.4e-99 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HNKEEIEE_00458 1.5e-101 yjbK S protein conserved in bacteria
HNKEEIEE_00459 6.9e-68 yjbL S Belongs to the UPF0738 family
HNKEEIEE_00460 1.2e-120 yjbM 2.7.6.5 S GTP pyrophosphokinase
HNKEEIEE_00461 4.9e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNKEEIEE_00462 4.4e-163 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HNKEEIEE_00463 5.8e-137 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HNKEEIEE_00464 8.6e-142 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HNKEEIEE_00467 3.5e-84 cotY S Spore coat protein
HNKEEIEE_00468 3.8e-60 S Protein of unknown function (DUF1360)
HNKEEIEE_00470 1.1e-80 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HNKEEIEE_00471 1.5e-83 spoVAC S stage V sporulation protein AC
HNKEEIEE_00472 1.2e-95 spoVAD I Stage V sporulation protein AD
HNKEEIEE_00473 1.1e-56 spoVAE S stage V sporulation protein
HNKEEIEE_00475 3.8e-38 spoVIF S Stage VI sporulation protein F
HNKEEIEE_00477 6.1e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNKEEIEE_00478 5.7e-94 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HNKEEIEE_00479 2.8e-134 yjcH P COG2382 Enterochelin esterase and related enzymes
HNKEEIEE_00482 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNKEEIEE_00483 2e-304 2.7.1.12, 2.7.1.17 G xylulose kinase
HNKEEIEE_00484 1.2e-247 yicJ G MFS/sugar transport protein
HNKEEIEE_00485 1.9e-38
HNKEEIEE_00486 3.5e-135 E IrrE N-terminal-like domain
HNKEEIEE_00487 3.2e-59 croE S Helix-turn-helix
HNKEEIEE_00488 0.0 M Peptidase M30
HNKEEIEE_00489 3.9e-284 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HNKEEIEE_00490 4.1e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HNKEEIEE_00491 4e-198 xylP G COGs COG2211 Na melibiose symporter and related transporter
HNKEEIEE_00492 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
HNKEEIEE_00493 5.4e-116 xylR GK Transcriptional regulator
HNKEEIEE_00495 1e-40
HNKEEIEE_00496 4.6e-38 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
HNKEEIEE_00497 1.8e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HNKEEIEE_00498 8e-194 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNKEEIEE_00499 6.4e-73 yjlC S Protein of unknown function (DUF1641)
HNKEEIEE_00500 7.4e-222 yjlD 1.6.99.3 C NADH dehydrogenase
HNKEEIEE_00501 2.2e-229 nrnB S phosphohydrolase (DHH superfamily)
HNKEEIEE_00502 2.4e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HNKEEIEE_00503 8.8e-130 yvpB NU protein conserved in bacteria
HNKEEIEE_00504 2.4e-50 tnrA K transcriptional
HNKEEIEE_00505 4.2e-109 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNKEEIEE_00506 1.9e-23 S Virus attachment protein p12 family
HNKEEIEE_00507 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HNKEEIEE_00508 2.4e-36 feoA P COG1918 Fe2 transport system protein A
HNKEEIEE_00509 2.2e-204 dapL 2.6.1.83 E Aminotransferase
HNKEEIEE_00510 1.6e-263 argH 4.3.2.1 E argininosuccinate lyase
HNKEEIEE_00511 6.2e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HNKEEIEE_00512 8.2e-179 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HNKEEIEE_00513 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HNKEEIEE_00514 1.5e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HNKEEIEE_00515 1.5e-225 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HNKEEIEE_00516 1.5e-141 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HNKEEIEE_00517 1.7e-232 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HNKEEIEE_00518 3e-198 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HNKEEIEE_00520 6.5e-81
HNKEEIEE_00521 2.9e-37 P catalase activity
HNKEEIEE_00522 1.7e-81
HNKEEIEE_00523 2.3e-30 cspD K Cold shock
HNKEEIEE_00525 9e-175 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HNKEEIEE_00526 9.9e-280 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HNKEEIEE_00527 3.3e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HNKEEIEE_00528 2.1e-76 yneK S Protein of unknown function (DUF2621)
HNKEEIEE_00529 4.6e-77 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HNKEEIEE_00530 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HNKEEIEE_00531 1e-128 ccdA O cytochrome c biogenesis protein
HNKEEIEE_00532 6.8e-28 yneF S UPF0154 protein
HNKEEIEE_00533 5.3e-72 yneE S Sporulation inhibitor of replication protein sirA
HNKEEIEE_00534 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HNKEEIEE_00535 3.4e-33 ynzC S UPF0291 protein
HNKEEIEE_00536 5.2e-116 yneB L resolvase
HNKEEIEE_00537 3.6e-52 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HNKEEIEE_00538 3.4e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HNKEEIEE_00539 2.9e-262 glnA 6.3.1.2 E glutamine synthetase
HNKEEIEE_00540 6.1e-64 glnR K transcriptional
HNKEEIEE_00541 0.0 S Dynamin family
HNKEEIEE_00542 3.6e-31
HNKEEIEE_00543 3.2e-142 f42a O prohibitin homologues
HNKEEIEE_00544 1.2e-233 pbuX F xanthine
HNKEEIEE_00545 1.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HNKEEIEE_00546 6.1e-301 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HNKEEIEE_00547 4.5e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HNKEEIEE_00548 9e-47 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HNKEEIEE_00549 4e-101 ypsA S Belongs to the UPF0398 family
HNKEEIEE_00550 5.4e-45 cotD S Inner spore coat protein D
HNKEEIEE_00552 8.1e-254 yprB L RNase_H superfamily
HNKEEIEE_00553 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HNKEEIEE_00554 7.2e-77 hspX O Belongs to the small heat shock protein (HSP20) family
HNKEEIEE_00556 1.8e-60 yppG S YppG-like protein
HNKEEIEE_00557 1.1e-62 yppE S Bacterial domain of unknown function (DUF1798)
HNKEEIEE_00560 5e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HNKEEIEE_00561 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNKEEIEE_00562 5.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNKEEIEE_00563 5.1e-130 dnaD L DNA replication protein DnaD
HNKEEIEE_00564 1.3e-251 asnS 6.1.1.22 J asparaginyl-tRNA
HNKEEIEE_00565 4e-215 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HNKEEIEE_00566 1.5e-74 ypmB S protein conserved in bacteria
HNKEEIEE_00567 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HNKEEIEE_00568 7.9e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HNKEEIEE_00569 2.5e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HNKEEIEE_00570 1.9e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HNKEEIEE_00571 1.4e-173 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HNKEEIEE_00572 4.9e-229 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HNKEEIEE_00573 6.3e-221 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HNKEEIEE_00574 5.6e-132 bshB1 S proteins, LmbE homologs
HNKEEIEE_00575 5.7e-149 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HNKEEIEE_00576 9.9e-58 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HNKEEIEE_00577 9.1e-161 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HNKEEIEE_00578 6.8e-81 queT S QueT transporter
HNKEEIEE_00579 2.4e-103 yugP S Zn-dependent protease
HNKEEIEE_00580 3.5e-143 ypjB S sporulation protein
HNKEEIEE_00581 1.1e-107 ypjA S membrane
HNKEEIEE_00582 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HNKEEIEE_00583 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
HNKEEIEE_00584 1e-98 qcrA C Menaquinol-cytochrome c reductase
HNKEEIEE_00585 1.1e-80 ypiF S Protein of unknown function (DUF2487)
HNKEEIEE_00586 3.5e-97 ypiB S Belongs to the UPF0302 family
HNKEEIEE_00587 5e-240 S COG0457 FOG TPR repeat
HNKEEIEE_00588 1.2e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HNKEEIEE_00589 5.2e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HNKEEIEE_00590 2.3e-209 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HNKEEIEE_00591 3.8e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HNKEEIEE_00592 1.4e-206 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HNKEEIEE_00593 5.3e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HNKEEIEE_00594 3.8e-145 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HNKEEIEE_00595 4.2e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HNKEEIEE_00596 8.6e-176 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HNKEEIEE_00597 6.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HNKEEIEE_00598 4.6e-146 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HNKEEIEE_00599 8.7e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HNKEEIEE_00600 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HNKEEIEE_00601 8.3e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HNKEEIEE_00602 7.6e-137 yphF
HNKEEIEE_00603 3.2e-08 yphE S Protein of unknown function (DUF2768)
HNKEEIEE_00604 1.6e-191 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HNKEEIEE_00605 5.5e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HNKEEIEE_00606 2.4e-19 yphA
HNKEEIEE_00607 7.3e-14 S YpzI-like protein
HNKEEIEE_00608 9.4e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HNKEEIEE_00609 1.1e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HNKEEIEE_00610 1e-116 ypfA M Flagellar protein YcgR
HNKEEIEE_00611 4.8e-257 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HNKEEIEE_00612 5.7e-149 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HNKEEIEE_00613 3.4e-126 prsW S Involved in the degradation of specific anti-sigma factors
HNKEEIEE_00614 3.7e-190 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HNKEEIEE_00615 4.4e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HNKEEIEE_00616 7e-98 mecB NOT Negative regulator of genetic competence (MecA)
HNKEEIEE_00617 3.4e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HNKEEIEE_00618 2.6e-30 cotJA S Spore coat associated protein JA (CotJA)
HNKEEIEE_00619 1.2e-44 cotJB S CotJB protein
HNKEEIEE_00620 2e-103 cotJC P Spore Coat
HNKEEIEE_00621 1.2e-79 ypbF S Protein of unknown function (DUF2663)
HNKEEIEE_00623 1.1e-101 ypbD S metal-dependent membrane protease
HNKEEIEE_00624 4.1e-278 recQ 3.6.4.12 L DNA helicase
HNKEEIEE_00625 4e-206 ypbB 5.1.3.1 S protein conserved in bacteria
HNKEEIEE_00626 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HNKEEIEE_00627 2.4e-93 lysP E amino acid
HNKEEIEE_00628 2.9e-128 lysP E amino acid
HNKEEIEE_00629 9.8e-115 K Transcriptional regulator
HNKEEIEE_00630 7e-207 ybhR V COG0842 ABC-type multidrug transport system, permease component
HNKEEIEE_00632 4.5e-129 V COG1131 ABC-type multidrug transport system, ATPase component
HNKEEIEE_00633 6.1e-70 S Hemerythrin HHE cation binding domain
HNKEEIEE_00634 5.1e-50
HNKEEIEE_00635 4.6e-42
HNKEEIEE_00636 3.2e-163 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HNKEEIEE_00637 2.6e-107 L Archaeal putative transposase ISC1217
HNKEEIEE_00639 8e-55 yjjL G Major facilitator superfamily
HNKEEIEE_00640 3.9e-120 yjjL G Major facilitator superfamily
HNKEEIEE_00641 2.6e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HNKEEIEE_00642 0.0 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HNKEEIEE_00643 5.6e-70 E Glyoxalase
HNKEEIEE_00646 6.2e-21 XK27_04860 K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNKEEIEE_00647 4.1e-198 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HNKEEIEE_00650 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HNKEEIEE_00651 6.1e-150 rbsC G Belongs to the binding-protein-dependent transport system permease family
HNKEEIEE_00652 6.9e-281 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HNKEEIEE_00653 1.4e-68 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HNKEEIEE_00654 1.1e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNKEEIEE_00655 2e-244 rbsR K transcriptional
HNKEEIEE_00656 6.4e-10 S transposase or invertase
HNKEEIEE_00658 4.7e-36 ywnB S NAD(P)H-binding
HNKEEIEE_00659 4.4e-86 folT 2.7.13.3 T ECF transporter, substrate-specific component
HNKEEIEE_00660 1.5e-35 yeeD O Belongs to the sulfur carrier protein TusA family
HNKEEIEE_00661 6.5e-193 yeeE S Sulphur transport
HNKEEIEE_00662 1.5e-205 ysdC G COG1363 Cellulase M and related proteins
HNKEEIEE_00663 1.5e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HNKEEIEE_00664 6.8e-93 S UPF0397 protein
HNKEEIEE_00665 0.0 ykoD P ABC transporter, ATP-binding protein
HNKEEIEE_00666 1.9e-150 cbiQ P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
HNKEEIEE_00667 7.1e-144 focA P Formate nitrite
HNKEEIEE_00668 9e-90 S NYN domain
HNKEEIEE_00669 2.6e-208 nifS 2.8.1.7 E Cysteine desulfurase
HNKEEIEE_00670 1e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HNKEEIEE_00671 3.2e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HNKEEIEE_00672 4.4e-208 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HNKEEIEE_00673 3.9e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HNKEEIEE_00674 4.6e-21
HNKEEIEE_00675 4.1e-149 S transposase or invertase
HNKEEIEE_00676 1.4e-121 comM O Mg chelatase subunit ChlI
HNKEEIEE_00677 5.1e-135 comM O Mg chelatase subunit ChlI
HNKEEIEE_00678 2.9e-53 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HNKEEIEE_00679 2.9e-136 yflN_1 S Metallo-beta-lactamase superfamily
HNKEEIEE_00680 1.4e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HNKEEIEE_00681 2.6e-111 yjlB S Cupin domain
HNKEEIEE_00682 3.2e-46
HNKEEIEE_00683 1e-27 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HNKEEIEE_00684 8.2e-117
HNKEEIEE_00685 2.3e-147 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
HNKEEIEE_00686 2e-21 M Spore coat protein
HNKEEIEE_00687 7.7e-140 I alpha/beta hydrolase fold
HNKEEIEE_00688 2.4e-158 S Aldo/keto reductase family
HNKEEIEE_00690 2.5e-98 1.5.1.38 S FMN reductase
HNKEEIEE_00691 3.3e-32 K sequence-specific DNA binding
HNKEEIEE_00692 5.9e-249 yhaO L Calcineurin-like phosphoesterase superfamily domain
HNKEEIEE_00693 0.0 L AAA domain
HNKEEIEE_00694 2.1e-157 mmgB 1.1.1.157 I Dehydrogenase
HNKEEIEE_00695 2.7e-247 yeeO V Mate efflux family protein
HNKEEIEE_00696 1.3e-09 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HNKEEIEE_00697 5.7e-112 yhbD K Protein of unknown function (DUF4004)
HNKEEIEE_00698 5e-226 yhdR 2.6.1.1 E Aminotransferase
HNKEEIEE_00699 6.9e-102 proA_2 H Methyltransferase
HNKEEIEE_00700 0.0 rafA 3.2.1.22 G Alpha-galactosidase
HNKEEIEE_00701 1.4e-211 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
HNKEEIEE_00702 5e-173 K Transcriptional regulator
HNKEEIEE_00703 1.2e-58 yrkC G Cupin domain
HNKEEIEE_00704 1.4e-270 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HNKEEIEE_00706 2.3e-281 yobO M Pectate lyase superfamily protein
HNKEEIEE_00707 6.3e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HNKEEIEE_00708 2.9e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HNKEEIEE_00709 1.3e-126 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HNKEEIEE_00711 2.6e-112 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HNKEEIEE_00712 1.2e-97 ywhH S Aminoacyl-tRNA editing domain
HNKEEIEE_00713 4.5e-205 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HNKEEIEE_00714 0.0 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HNKEEIEE_00715 1e-20 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HNKEEIEE_00716 2.5e-84 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HNKEEIEE_00717 1.7e-57 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HNKEEIEE_00719 2.6e-169 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HNKEEIEE_00720 1.3e-178 S Nuclease-related domain
HNKEEIEE_00721 6.7e-92
HNKEEIEE_00722 2.3e-173 czcD P COG1230 Co Zn Cd efflux system component
HNKEEIEE_00723 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HNKEEIEE_00724 1.6e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
HNKEEIEE_00725 6.9e-181 mvaD 4.1.1.33 I GHMP kinases N terminal domain
HNKEEIEE_00726 1e-201 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
HNKEEIEE_00727 1.2e-112 yhfK GM NmrA-like family
HNKEEIEE_00728 3.3e-30 K PTS system fructose IIA component
HNKEEIEE_00729 1e-231 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HNKEEIEE_00730 1.1e-110 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNKEEIEE_00731 2.3e-38 gcvR T Belongs to the UPF0237 family
HNKEEIEE_00732 1.4e-248 XK27_08635 S UPF0210 protein
HNKEEIEE_00733 2.8e-94 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
HNKEEIEE_00734 1.2e-83 cotF M Spore coat protein
HNKEEIEE_00735 1.1e-175 iolS C Aldo keto reductase
HNKEEIEE_00736 3.8e-99 ydjA C Nitroreductase family
HNKEEIEE_00737 3.2e-253 E COG1113 Gamma-aminobutyrate permease and related permeases
HNKEEIEE_00739 2e-16
HNKEEIEE_00740 3.4e-272 dtpT E amino acid peptide transporter
HNKEEIEE_00741 1.9e-278 lysP E amino acid
HNKEEIEE_00743 4.3e-98 puuR K Cupin domain
HNKEEIEE_00744 2.5e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HNKEEIEE_00745 1.1e-139 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
HNKEEIEE_00746 5.4e-139 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
HNKEEIEE_00747 9.8e-205 potD E COG0687 Spermidine putrescine-binding periplasmic protein
HNKEEIEE_00748 2.5e-245 H HemY protein
HNKEEIEE_00749 8.2e-252 E amino acid
HNKEEIEE_00750 1.8e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HNKEEIEE_00751 3e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HNKEEIEE_00752 2.5e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HNKEEIEE_00753 6.9e-251 E Amino acid permease
HNKEEIEE_00754 2.7e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HNKEEIEE_00755 2.6e-233 amt P Ammonium transporter
HNKEEIEE_00756 1.9e-128 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HNKEEIEE_00757 3e-159 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HNKEEIEE_00758 4.6e-123 citT T response regulator
HNKEEIEE_00759 4.2e-226 citH C Citrate transporter
HNKEEIEE_00760 1.4e-181 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HNKEEIEE_00761 0.0 helD 3.6.4.12 L DNA helicase
HNKEEIEE_00763 6.5e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HNKEEIEE_00764 5.5e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HNKEEIEE_00765 1.2e-288 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HNKEEIEE_00766 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HNKEEIEE_00767 1.4e-210 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNKEEIEE_00768 1.9e-121 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HNKEEIEE_00770 5.3e-43
HNKEEIEE_00771 5.9e-279 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HNKEEIEE_00772 1.7e-193 T HD domain
HNKEEIEE_00774 2.2e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HNKEEIEE_00775 6.4e-96 S Belongs to the UPF0312 family
HNKEEIEE_00776 7.5e-14 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
HNKEEIEE_00777 8e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HNKEEIEE_00778 2.2e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HNKEEIEE_00779 4.5e-97 yvbF K Belongs to the GbsR family
HNKEEIEE_00780 1.6e-97 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
HNKEEIEE_00781 9.4e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HNKEEIEE_00782 7.8e-41 fer C Ferredoxin
HNKEEIEE_00783 6.2e-97 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HNKEEIEE_00784 1.7e-136 M COG0739 Membrane proteins related to metalloendopeptidases
HNKEEIEE_00785 0.0 resE 2.7.13.3 T Histidine kinase
HNKEEIEE_00786 3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNKEEIEE_00787 1.4e-172 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HNKEEIEE_00788 7.6e-26 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HNKEEIEE_00789 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HNKEEIEE_00790 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HNKEEIEE_00791 2.9e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HNKEEIEE_00792 1.9e-87 spmB S Spore maturation protein
HNKEEIEE_00793 5.2e-96 spmA S Spore maturation protein
HNKEEIEE_00794 3.6e-202 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HNKEEIEE_00795 1.2e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HNKEEIEE_00796 8.5e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HNKEEIEE_00798 2.2e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNKEEIEE_00799 4.7e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HNKEEIEE_00800 4.9e-271 spoVAF EG Stage V sporulation protein AF
HNKEEIEE_00801 8e-105 spoVAEA S Stage V sporulation protein AE
HNKEEIEE_00802 1.9e-66 spoVAB S Stage V sporulation protein AB
HNKEEIEE_00803 6.5e-108 spoVAA S Stage V sporulation protein AA
HNKEEIEE_00804 1.4e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNKEEIEE_00805 2e-74 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HNKEEIEE_00806 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HNKEEIEE_00807 5.6e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HNKEEIEE_00809 3.6e-168 xerD L recombinase XerD
HNKEEIEE_00810 1.7e-34 S Protein of unknown function (DUF4227)
HNKEEIEE_00811 1.6e-85 fur P Belongs to the Fur family
HNKEEIEE_00812 2.9e-103 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HNKEEIEE_00813 2.1e-224 yqxK 3.6.4.12 L DNA helicase
HNKEEIEE_00814 2.9e-96 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HNKEEIEE_00816 1.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HNKEEIEE_00817 1.6e-09 S Protein of unknown function (DUF3886)
HNKEEIEE_00818 5.6e-110 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HNKEEIEE_00819 1.4e-212 yaaN P Belongs to the TelA family
HNKEEIEE_00820 1.2e-174 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HNKEEIEE_00821 1.9e-240 yaaH_2 M Glycoside Hydrolase Family
HNKEEIEE_00823 2.7e-55 S YolD-like protein
HNKEEIEE_00824 1.3e-240 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNKEEIEE_00825 2.6e-146 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HNKEEIEE_00826 2.6e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNKEEIEE_00827 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HNKEEIEE_00828 6.4e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HNKEEIEE_00829 1e-226 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNKEEIEE_00830 1.2e-77 cheW NT COG0835 Chemotaxis signal transduction protein
HNKEEIEE_00831 3.3e-203 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HNKEEIEE_00832 1.8e-92 yqjB S protein conserved in bacteria
HNKEEIEE_00833 9.3e-77 yqiW S Belongs to the UPF0403 family
HNKEEIEE_00834 7.1e-164 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HNKEEIEE_00835 1e-216 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HNKEEIEE_00836 3.9e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HNKEEIEE_00837 5.9e-188 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HNKEEIEE_00838 3e-262 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HNKEEIEE_00839 1.5e-208 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HNKEEIEE_00840 2e-283 bkdR 2.7.13.3 KT Transcriptional regulator
HNKEEIEE_00841 1.7e-35 yqzF S Protein of unknown function (DUF2627)
HNKEEIEE_00842 6.5e-131 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HNKEEIEE_00843 2e-138 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HNKEEIEE_00844 1.6e-233 rseP 3.4.21.116 M Stage IV sporulation protein B
HNKEEIEE_00845 3.3e-295 recN L May be involved in recombinational repair of damaged DNA
HNKEEIEE_00846 9.2e-80 argR K Regulates arginine biosynthesis genes
HNKEEIEE_00847 2.2e-108 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HNKEEIEE_00848 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HNKEEIEE_00849 3.1e-169 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HNKEEIEE_00850 2.9e-105 thiT S Proton-coupled thiamine transporter YuaJ
HNKEEIEE_00851 1.1e-129 yoqW S Belongs to the SOS response-associated peptidase family
HNKEEIEE_00852 3.5e-193 yceA S Belongs to the UPF0176 family
HNKEEIEE_00853 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNKEEIEE_00854 3.2e-161 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HNKEEIEE_00856 8.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNKEEIEE_00857 3.8e-83 rok S Repressor of ComK
HNKEEIEE_00858 5.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HNKEEIEE_00859 1.6e-201 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HNKEEIEE_00860 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HNKEEIEE_00861 1.5e-74 yozR S COG0071 Molecular chaperone (small heat shock protein)
HNKEEIEE_00862 2.4e-251 arlS 2.7.13.3 T Histidine kinase
HNKEEIEE_00863 1.3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNKEEIEE_00864 3e-221 ymfD EGP Major facilitator Superfamily
HNKEEIEE_00865 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HNKEEIEE_00866 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HNKEEIEE_00868 1.5e-112 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HNKEEIEE_00869 1.6e-133 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HNKEEIEE_00870 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HNKEEIEE_00871 1e-187 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HNKEEIEE_00873 2e-247 norM V Multidrug efflux pump
HNKEEIEE_00874 2.9e-99 ykwD J protein with SCP PR1 domains
HNKEEIEE_00875 3.9e-67 ypoP K transcriptional
HNKEEIEE_00876 2.8e-274 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HNKEEIEE_00877 4.1e-147 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HNKEEIEE_00878 7.5e-25 yozD S YozD-like protein
HNKEEIEE_00879 2.3e-116 yodN
HNKEEIEE_00880 3e-36 yozE S Belongs to the UPF0346 family
HNKEEIEE_00881 3.2e-192 NT CHASE3 domain
HNKEEIEE_00883 1.6e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HNKEEIEE_00884 1.6e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNKEEIEE_00885 4.2e-277 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
HNKEEIEE_00886 5.1e-96 ypmS S protein conserved in bacteria
HNKEEIEE_00887 3.9e-142 ypmR E COG2755 Lysophospholipase L1 and related esterases
HNKEEIEE_00888 2.2e-111 hlyIII S protein, Hemolysin III
HNKEEIEE_00889 1.8e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNKEEIEE_00890 9.7e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HNKEEIEE_00891 2.5e-106 ypjP S YpjP-like protein
HNKEEIEE_00892 2.3e-75 yphP S Belongs to the UPF0403 family
HNKEEIEE_00893 1.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
HNKEEIEE_00894 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HNKEEIEE_00895 3.3e-86
HNKEEIEE_00896 3.8e-70 K Helix-turn-helix domain
HNKEEIEE_00897 7.5e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HNKEEIEE_00898 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNKEEIEE_00899 3.5e-228 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNKEEIEE_00900 4.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNKEEIEE_00901 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HNKEEIEE_00902 3.3e-68 yqhY S protein conserved in bacteria
HNKEEIEE_00903 6.2e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HNKEEIEE_00904 4.4e-80 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HNKEEIEE_00905 1.1e-23 spoIIIAH S SpoIIIAH-like protein
HNKEEIEE_00906 5.5e-79 spoIIIAH S SpoIIIAH-like protein
HNKEEIEE_00907 1.1e-110 spoIIIAG S stage III sporulation protein AG
HNKEEIEE_00908 2.4e-105 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HNKEEIEE_00909 1.3e-173 spoIIIAE S stage III sporulation protein AE
HNKEEIEE_00910 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HNKEEIEE_00911 1.4e-27 spoIIIAC S stage III sporulation protein AC
HNKEEIEE_00912 3.7e-85 spoIIIAB S Stage III sporulation protein
HNKEEIEE_00913 2.3e-170 spoIIIAA S stage III sporulation protein AA
HNKEEIEE_00914 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNKEEIEE_00915 6.4e-156 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HNKEEIEE_00916 9.6e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HNKEEIEE_00917 3.1e-86 yqhR S Conserved membrane protein YqhR
HNKEEIEE_00918 1.5e-164 yqhQ S Protein of unknown function (DUF1385)
HNKEEIEE_00919 6.7e-12 yqhP
HNKEEIEE_00920 1.9e-166 yqhO S esterase of the alpha-beta hydrolase superfamily
HNKEEIEE_00921 1.4e-95 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Belongs to the thiolase family
HNKEEIEE_00922 2.2e-17 ycgT 1.18.1.2, 1.19.1.1 C reductase
HNKEEIEE_00923 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HNKEEIEE_00924 6.8e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HNKEEIEE_00925 4.5e-67 yqhL P COG0607 Rhodanese-related sulfurtransferase
HNKEEIEE_00926 3.7e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HNKEEIEE_00927 5.3e-256 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HNKEEIEE_00928 2.9e-215 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HNKEEIEE_00929 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HNKEEIEE_00930 1.4e-152 yqhG S Bacterial protein YqhG of unknown function
HNKEEIEE_00931 1.1e-09 yqzE S YqzE-like protein
HNKEEIEE_00932 3.8e-99 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HNKEEIEE_00933 9e-57 S ComG operon protein 7
HNKEEIEE_00934 4.9e-79 comGF U COG4940 Competence protein ComGF
HNKEEIEE_00936 7.9e-76 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
HNKEEIEE_00937 5.3e-50 comGC U Required for transformation and DNA binding
HNKEEIEE_00938 3.9e-176 comGB NU COG1459 Type II secretory pathway, component PulF
HNKEEIEE_00939 1.3e-75 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNKEEIEE_00940 7.9e-30 csoR_2 S Metal-sensitive transcriptional repressor
HNKEEIEE_00941 4.3e-68 lrpC K Transcriptional regulator
HNKEEIEE_00942 8.6e-72 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNKEEIEE_00943 2.7e-224 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HNKEEIEE_00944 1.3e-27 yhjC S Protein of unknown function (DUF3311)
HNKEEIEE_00945 7.2e-267 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNKEEIEE_00948 3.1e-33 S Protein of unknown function (DUF2933)
HNKEEIEE_00950 8.5e-249 T PhoQ Sensor
HNKEEIEE_00951 1.5e-126 KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNKEEIEE_00952 4.9e-91 ydhK M Protein of unknown function (DUF1541)
HNKEEIEE_00953 2.7e-100 VY92_08700 S Enoyl-(Acyl carrier protein) reductase
HNKEEIEE_00954 7e-12 recN L Putative cell-wall binding lipoprotein
HNKEEIEE_00955 6.2e-171 nodB1 G deacetylase
HNKEEIEE_00958 3.3e-242 P Voltage gated chloride channel
HNKEEIEE_00959 1.5e-49 P Rhodanese domain protein
HNKEEIEE_00960 1.9e-37 yhjE S protein conserved in bacteria
HNKEEIEE_00961 3.1e-147 yokF 3.1.31.1 L RNA catabolic process
HNKEEIEE_00962 2.5e-73 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HNKEEIEE_00963 3.7e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HNKEEIEE_00964 1.2e-129 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HNKEEIEE_00965 2.3e-254 araP EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HNKEEIEE_00966 8.6e-306 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HNKEEIEE_00967 7.3e-214 araR K transcriptional
HNKEEIEE_00968 1.1e-260 NT chemotaxis protein
HNKEEIEE_00969 3.1e-127 plsB 2.3.1.15 I Acyl-transferase
HNKEEIEE_00970 7.9e-202 2.4.1.83 GT2 M Glycosyl transferase family 2
HNKEEIEE_00971 1.6e-132 IQ Enoyl-(Acyl carrier protein) reductase
HNKEEIEE_00972 1.3e-71 yuiD S protein conserved in bacteria
HNKEEIEE_00973 1.3e-218 solA 1.5.3.1 E FAD dependent oxidoreductase
HNKEEIEE_00974 5.8e-219 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
HNKEEIEE_00975 8.8e-281 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HNKEEIEE_00976 1.4e-170 4.3.1.12 E ornithine cyclodeaminase
HNKEEIEE_00979 1.1e-181 yugO P COG1226 Kef-type K transport systems
HNKEEIEE_00980 1.3e-259 pgi 5.3.1.9 G Belongs to the GPI family
HNKEEIEE_00981 6.7e-34 yuzA S Domain of unknown function (DUF378)
HNKEEIEE_00982 4.9e-84 K Bacterial transcription activator, effector binding domain
HNKEEIEE_00983 1.2e-64 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HNKEEIEE_00984 4.8e-45 ykvR S Protein of unknown function (DUF3219)
HNKEEIEE_00985 3e-184 S transport system, ATPase component
HNKEEIEE_00986 8.6e-81 S ABC-2 family transporter protein
HNKEEIEE_00987 5.1e-123 L Archaeal putative transposase ISC1217
HNKEEIEE_00988 1.3e-181 yaaC S YaaC-like Protein
HNKEEIEE_00989 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HNKEEIEE_00990 6.5e-251 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HNKEEIEE_00991 1.6e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HNKEEIEE_00992 1.1e-101 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HNKEEIEE_00993 2.9e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HNKEEIEE_00994 6.5e-09
HNKEEIEE_00995 3.3e-126 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HNKEEIEE_00996 3.8e-119 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HNKEEIEE_00997 1.1e-247 yaaH M Glycoside Hydrolase Family
HNKEEIEE_00998 2.1e-88 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HNKEEIEE_00999 1.4e-306 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNKEEIEE_01000 5e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNKEEIEE_01001 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HNKEEIEE_01002 3.4e-08 yaaL S Protein of unknown function (DUF2508)
HNKEEIEE_01003 4.8e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HNKEEIEE_01004 5.4e-75 ctsR K Belongs to the CtsR family
HNKEEIEE_01005 1.3e-99 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HNKEEIEE_01006 1.4e-190 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HNKEEIEE_01007 0.0 clpC O Belongs to the ClpA ClpB family
HNKEEIEE_01008 1.1e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNKEEIEE_01009 6.9e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HNKEEIEE_01010 7.5e-118 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HNKEEIEE_01011 2.1e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HNKEEIEE_01012 1.9e-283 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNKEEIEE_01013 7.7e-115 cysE 2.3.1.30 E Serine acetyltransferase
HNKEEIEE_01014 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HNKEEIEE_01015 3e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HNKEEIEE_01016 8.2e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNKEEIEE_01017 8.7e-90 yacP S RNA-binding protein containing a PIN domain
HNKEEIEE_01018 1.2e-109 sigH K Belongs to the sigma-70 factor family
HNKEEIEE_01019 6.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HNKEEIEE_01020 5.4e-95 nusG K Participates in transcription elongation, termination and antitermination
HNKEEIEE_01021 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HNKEEIEE_01022 1.3e-125 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HNKEEIEE_01023 1e-08 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HNKEEIEE_01024 2.7e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HNKEEIEE_01025 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HNKEEIEE_01026 4.2e-112 rsmC 2.1.1.172 J Methyltransferase
HNKEEIEE_01027 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNKEEIEE_01028 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNKEEIEE_01029 1.2e-36 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
HNKEEIEE_01030 3.3e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HNKEEIEE_01031 2.1e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HNKEEIEE_01032 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HNKEEIEE_01033 4e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNKEEIEE_01034 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HNKEEIEE_01035 2.6e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HNKEEIEE_01036 1.1e-107 rplD J Forms part of the polypeptide exit tunnel
HNKEEIEE_01037 1.8e-41 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HNKEEIEE_01038 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HNKEEIEE_01039 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HNKEEIEE_01040 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HNKEEIEE_01041 1.4e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HNKEEIEE_01042 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HNKEEIEE_01043 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HNKEEIEE_01044 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HNKEEIEE_01045 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HNKEEIEE_01046 9.6e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNKEEIEE_01047 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNKEEIEE_01048 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNKEEIEE_01049 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNKEEIEE_01050 1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HNKEEIEE_01051 4.7e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HNKEEIEE_01052 6.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNKEEIEE_01053 4.1e-23 rpmD J Ribosomal protein L30
HNKEEIEE_01054 1.2e-71 rplO J binds to the 23S rRNA
HNKEEIEE_01055 3.4e-228 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HNKEEIEE_01056 9.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HNKEEIEE_01057 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HNKEEIEE_01058 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HNKEEIEE_01059 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HNKEEIEE_01060 1.7e-168 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNKEEIEE_01061 2.6e-62 rplQ J Ribosomal protein L17
HNKEEIEE_01062 3.7e-157 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNKEEIEE_01063 2.2e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNKEEIEE_01064 1e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNKEEIEE_01065 1.4e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HNKEEIEE_01066 3.8e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HNKEEIEE_01067 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HNKEEIEE_01068 3.3e-09 S Protein conserved in bacteria
HNKEEIEE_01070 3.7e-226 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HNKEEIEE_01071 3.5e-114 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HNKEEIEE_01072 4.7e-274 lysP E amino acid
HNKEEIEE_01073 8.8e-83 ybaK S Protein of unknown function (DUF2521)
HNKEEIEE_01074 2.4e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HNKEEIEE_01075 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HNKEEIEE_01076 4.1e-61 gerD S Spore gernimation protein
HNKEEIEE_01077 2.1e-101 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HNKEEIEE_01078 2.3e-195 L RNA-directed DNA polymerase (reverse transcriptase)
HNKEEIEE_01079 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HNKEEIEE_01080 3e-72 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HNKEEIEE_01081 1.2e-31 cspD K Cold-shock protein
HNKEEIEE_01083 3.6e-27 ypeQ S Zinc-finger
HNKEEIEE_01084 4.6e-171 polA 2.7.7.7 L 5'3' exonuclease
HNKEEIEE_01085 2.1e-246 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HNKEEIEE_01086 1.6e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNKEEIEE_01087 8.4e-176 spoVK O stage V sporulation protein K
HNKEEIEE_01088 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HNKEEIEE_01089 3e-190 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HNKEEIEE_01092 1.9e-22 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
HNKEEIEE_01093 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HNKEEIEE_01094 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HNKEEIEE_01095 6.2e-99 cotE S Outer spore coat protein E (CotE)
HNKEEIEE_01096 7.7e-59 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HNKEEIEE_01097 2.6e-299 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HNKEEIEE_01098 1.2e-192 E Amino acid permease
HNKEEIEE_01099 3.5e-249 yegQ O COG0826 Collagenase and related proteases
HNKEEIEE_01100 1.9e-169 yegQ O Peptidase U32
HNKEEIEE_01101 3.3e-37 spoVS S Stage V sporulation protein S
HNKEEIEE_01102 1.9e-152 ymdB S protein conserved in bacteria
HNKEEIEE_01103 5.6e-217 rny S Endoribonuclease that initiates mRNA decay
HNKEEIEE_01104 6.4e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HNKEEIEE_01105 1e-226 cinA 3.5.1.42 S Belongs to the CinA family
HNKEEIEE_01106 1.3e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNKEEIEE_01107 2.8e-139 ymfM S protein conserved in bacteria
HNKEEIEE_01108 1e-142 ymfK S Protein of unknown function (DUF3388)
HNKEEIEE_01109 6.4e-41 ymfJ S Protein of unknown function (DUF3243)
HNKEEIEE_01110 2.7e-138 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HNKEEIEE_01111 1.8e-245 ymfH S zinc protease
HNKEEIEE_01112 2.1e-238 ymfF S Peptidase M16
HNKEEIEE_01113 1.8e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
HNKEEIEE_01114 2.6e-186 yufP S Belongs to the binding-protein-dependent transport system permease family
HNKEEIEE_01115 1.8e-284 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HNKEEIEE_01116 9.1e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HNKEEIEE_01117 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HNKEEIEE_01118 4.3e-35 S YlzJ-like protein
HNKEEIEE_01119 1.1e-130 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HNKEEIEE_01120 0.0 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNKEEIEE_01121 3.9e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNKEEIEE_01122 1.1e-228 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HNKEEIEE_01123 1.7e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNKEEIEE_01124 2.6e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HNKEEIEE_01125 1.5e-186 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HNKEEIEE_01126 8.1e-38 ymxH S YlmC YmxH family
HNKEEIEE_01127 1.7e-232 pepR S Belongs to the peptidase M16 family
HNKEEIEE_01128 2.3e-209 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HNKEEIEE_01129 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HNKEEIEE_01130 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HNKEEIEE_01131 1.2e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HNKEEIEE_01132 2.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HNKEEIEE_01133 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HNKEEIEE_01134 8.6e-44 ylxP S protein conserved in bacteria
HNKEEIEE_01135 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HNKEEIEE_01136 2.9e-48 ylxQ J ribosomal protein
HNKEEIEE_01137 8.2e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
HNKEEIEE_01138 2.8e-224 nusA K Participates in both transcription termination and antitermination
HNKEEIEE_01139 7.1e-83 rimP S Required for maturation of 30S ribosomal subunits
HNKEEIEE_01140 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNKEEIEE_01141 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HNKEEIEE_01142 3.3e-236 rasP M zinc metalloprotease
HNKEEIEE_01143 1.7e-194 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HNKEEIEE_01144 5.9e-146 cdsA 2.7.7.41 S Belongs to the CDS family
HNKEEIEE_01145 7.4e-149 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNKEEIEE_01146 6.9e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HNKEEIEE_01147 1.1e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HNKEEIEE_01148 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HNKEEIEE_01149 3.1e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
HNKEEIEE_01150 1.4e-69 ylxL
HNKEEIEE_01151 1.1e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNKEEIEE_01152 3.4e-83 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HNKEEIEE_01153 1.1e-113 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HNKEEIEE_01154 8.2e-70 cheW NT COG0835 Chemotaxis signal transduction protein
HNKEEIEE_01155 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HNKEEIEE_01156 5.8e-115 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HNKEEIEE_01157 1.2e-144 flhG D Belongs to the ParA family
HNKEEIEE_01158 2.8e-197 flhF N Flagellar biosynthesis regulator FlhF
HNKEEIEE_01159 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNKEEIEE_01160 1.6e-186 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNKEEIEE_01161 3.3e-133 fliR N Flagellar biosynthetic protein FliR
HNKEEIEE_01162 1.5e-37 fliQ N Role in flagellar biosynthesis
HNKEEIEE_01163 2.6e-107 fliP N Plays a role in the flagellum-specific transport system
HNKEEIEE_01164 8.4e-117 fliZ N Flagellar biosynthesis protein, FliO
HNKEEIEE_01165 5.5e-59 cheB 3.1.1.61, 3.5.1.44 T response regulator
HNKEEIEE_01166 1.3e-175 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNKEEIEE_01167 3.4e-183 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HNKEEIEE_01168 7.9e-65 fliL N Controls the rotational direction of flagella during chemotaxis
HNKEEIEE_01169 3.9e-131 flgG N Flagellar basal body rod
HNKEEIEE_01170 1.9e-72 flg N Putative flagellar
HNKEEIEE_01171 9.6e-107 flgD N Flagellar basal body rod modification protein
HNKEEIEE_01172 6.2e-285 fliK N Flagellar hook-length control
HNKEEIEE_01173 1e-36 ylxF S MgtE intracellular N domain
HNKEEIEE_01174 2.2e-70 fliJ N Flagellar biosynthesis chaperone
HNKEEIEE_01175 4e-248 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HNKEEIEE_01176 3e-131 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HNKEEIEE_01177 2.7e-164 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HNKEEIEE_01178 4.6e-243 fliF N The M ring may be actively involved in energy transduction
HNKEEIEE_01179 8.4e-40 fliE N Flagellar hook-basal body complex protein FliE
HNKEEIEE_01180 1.5e-74 flgC N Belongs to the flagella basal body rod proteins family
HNKEEIEE_01181 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HNKEEIEE_01182 3e-134 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HNKEEIEE_01183 1.1e-144 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HNKEEIEE_01184 1.1e-33 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HNKEEIEE_01185 4.3e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HNKEEIEE_01186 4.3e-169 xerC L tyrosine recombinase XerC
HNKEEIEE_01189 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNKEEIEE_01190 2e-163 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HNKEEIEE_01191 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HNKEEIEE_01192 4.8e-213 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HNKEEIEE_01193 3.6e-45 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HNKEEIEE_01194 6e-230 CP_1081 D nuclear chromosome segregation
HNKEEIEE_01195 7.9e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNKEEIEE_01196 4.7e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNKEEIEE_01197 3.6e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HNKEEIEE_01198 2.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HNKEEIEE_01199 1.7e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HNKEEIEE_01200 1.2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HNKEEIEE_01201 1.1e-60 ylqD S YlqD protein
HNKEEIEE_01202 5.5e-36 ylqC S Belongs to the UPF0109 family
HNKEEIEE_01203 1.7e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HNKEEIEE_01204 1.1e-242 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNKEEIEE_01205 2.9e-51 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HNKEEIEE_01206 4.6e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HNKEEIEE_01207 2.8e-114 smc D Required for chromosome condensation and partitioning
HNKEEIEE_01208 0.0 smc D Required for chromosome condensation and partitioning
HNKEEIEE_01209 2.4e-133 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HNKEEIEE_01210 1.3e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNKEEIEE_01211 2.1e-129 IQ reductase
HNKEEIEE_01212 3.5e-158 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HNKEEIEE_01213 8.9e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HNKEEIEE_01214 5.1e-98 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HNKEEIEE_01215 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNKEEIEE_01216 3.5e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HNKEEIEE_01217 6.6e-119 sdaAB 4.3.1.17 E L-serine dehydratase
HNKEEIEE_01218 3e-301 yloV S kinase related to dihydroxyacetone kinase
HNKEEIEE_01219 6.5e-60 asp S protein conserved in bacteria
HNKEEIEE_01220 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HNKEEIEE_01221 2.8e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
HNKEEIEE_01222 4.1e-113 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HNKEEIEE_01223 1.2e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HNKEEIEE_01224 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HNKEEIEE_01225 1.2e-135 stp 3.1.3.16 T phosphatase
HNKEEIEE_01226 2.2e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNKEEIEE_01227 3.7e-179 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HNKEEIEE_01228 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNKEEIEE_01229 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNKEEIEE_01230 1.1e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNKEEIEE_01231 3.4e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HNKEEIEE_01232 3.7e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HNKEEIEE_01233 7.7e-46 ylzA S Belongs to the UPF0296 family
HNKEEIEE_01234 7.1e-153 yicC S stress-induced protein
HNKEEIEE_01235 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HNKEEIEE_01236 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HNKEEIEE_01237 5.6e-167 yocS S -transporter
HNKEEIEE_01238 7e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HNKEEIEE_01239 7.4e-91 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HNKEEIEE_01240 1.9e-132 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HNKEEIEE_01241 9.5e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HNKEEIEE_01242 1.3e-137 ycsF S Belongs to the UPF0271 (lamB) family
HNKEEIEE_01243 7.6e-118 S Protein of unknown function (DUF969)
HNKEEIEE_01244 4.2e-167 S Protein of unknown function (DUF979)
HNKEEIEE_01245 6.1e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HNKEEIEE_01246 2.8e-225 pbuO_1 S permease
HNKEEIEE_01247 2.9e-213 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNKEEIEE_01248 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HNKEEIEE_01249 2.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HNKEEIEE_01250 1e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HNKEEIEE_01251 8.4e-235 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HNKEEIEE_01252 8.5e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HNKEEIEE_01253 4e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HNKEEIEE_01254 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HNKEEIEE_01256 1.4e-83 S SMI1-KNR4 cell-wall
HNKEEIEE_01257 2.5e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HNKEEIEE_01258 7.1e-162 P ABC transporter substrate-binding protein
HNKEEIEE_01259 2e-55 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HNKEEIEE_01260 6.2e-143 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HNKEEIEE_01261 7.6e-135 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HNKEEIEE_01262 2.5e-138 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HNKEEIEE_01263 5.8e-97 ssuE 1.5.1.38 S FMN reductase
HNKEEIEE_01264 7e-23 S Uncharacterized small protein (DUF2292)
HNKEEIEE_01265 9.2e-305 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HNKEEIEE_01266 1.3e-54 XK27_04815 S Membrane transport protein
HNKEEIEE_01267 9.4e-81 XK27_04815 S Membrane transport protein
HNKEEIEE_01269 1.5e-30 S Domain of unknown function (DUF202)
HNKEEIEE_01270 1.8e-103 P Integral membrane protein TerC family
HNKEEIEE_01272 9.5e-99 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HNKEEIEE_01273 2.5e-80 K helix_turn_helix multiple antibiotic resistance protein
HNKEEIEE_01274 0.0 yfiB V ABC transporter
HNKEEIEE_01275 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HNKEEIEE_01276 5.4e-141 tesE Q COG3971 2-keto-4-pentenoate hydratase
HNKEEIEE_01277 7.8e-76 nsrR K Transcriptional regulator
HNKEEIEE_01278 4.5e-230 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HNKEEIEE_01279 1.6e-124 S membrane transporter protein
HNKEEIEE_01280 4e-75 dps P Ferritin-like domain
HNKEEIEE_01281 3.7e-182 mocA S Oxidoreductase
HNKEEIEE_01282 2.1e-207 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HNKEEIEE_01283 4.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HNKEEIEE_01284 5.8e-85
HNKEEIEE_01285 9.5e-144 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HNKEEIEE_01286 2.8e-28 sspD S small acid-soluble spore protein
HNKEEIEE_01287 4.3e-19 S Stage 0 Sporulation Regulatory protein
HNKEEIEE_01289 3.4e-288 kinE 2.7.13.3 T Histidine kinase
HNKEEIEE_01290 5.2e-78 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNKEEIEE_01291 4.3e-71 XK27_09985 S Protein of unknown function (DUF1232)
HNKEEIEE_01293 0.0 clpE O Belongs to the ClpA ClpB family
HNKEEIEE_01294 4.3e-181 ykvI S membrane
HNKEEIEE_01295 7.3e-104 S Abortive infection protein
HNKEEIEE_01296 4.2e-26 ykvS S protein conserved in bacteria
HNKEEIEE_01297 8.2e-17
HNKEEIEE_01298 3.2e-40 ptsH G phosphocarrier protein HPr
HNKEEIEE_01299 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNKEEIEE_01300 6.2e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNKEEIEE_01301 4e-156 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HNKEEIEE_01302 1.9e-217 patA 2.6.1.1 E Aminotransferase
HNKEEIEE_01303 6.4e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
HNKEEIEE_01304 1.1e-86 ykyB S YkyB-like protein
HNKEEIEE_01305 0.0 ydgH S drug exporters of the RND superfamily
HNKEEIEE_01306 9.7e-17 T Diguanylate cyclase
HNKEEIEE_01307 1e-31
HNKEEIEE_01308 1.7e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNKEEIEE_01309 7.9e-171 3.5.1.4 C Acetamidase
HNKEEIEE_01310 5.8e-39 ykuJ S protein conserved in bacteria
HNKEEIEE_01311 6.5e-78 ykuL S CBS domain
HNKEEIEE_01312 7e-158 ccpC K Transcriptional regulator
HNKEEIEE_01313 2.3e-69 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HNKEEIEE_01314 3.6e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HNKEEIEE_01315 1.8e-18 S YhfH-like protein
HNKEEIEE_01316 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNKEEIEE_01317 6.8e-30 ykzG S Belongs to the UPF0356 family
HNKEEIEE_01318 1.6e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HNKEEIEE_01319 4.5e-180 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HNKEEIEE_01320 3.7e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HNKEEIEE_01321 5.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HNKEEIEE_01322 4.1e-34
HNKEEIEE_01324 4.2e-275 speA 4.1.1.19 E Arginine
HNKEEIEE_01325 2.3e-47 yktA S Belongs to the UPF0223 family
HNKEEIEE_01326 4e-118 yktB S Belongs to the UPF0637 family
HNKEEIEE_01327 4e-24
HNKEEIEE_01328 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
HNKEEIEE_01329 6e-25 S Family of unknown function (DUF5325)
HNKEEIEE_01330 0.0 typA T GTP-binding protein TypA
HNKEEIEE_01331 2.7e-52 ylaH S YlaH-like protein
HNKEEIEE_01332 1.6e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HNKEEIEE_01333 9.1e-89 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HNKEEIEE_01335 4.3e-169 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HNKEEIEE_01337 3.2e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HNKEEIEE_01338 6.4e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HNKEEIEE_01339 5.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNKEEIEE_01340 1.8e-221 ybbR S protein conserved in bacteria
HNKEEIEE_01341 5.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNKEEIEE_01342 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HNKEEIEE_01344 1.2e-38 M1-431 S Protein of unknown function (DUF1706)
HNKEEIEE_01345 3.6e-145 3.1.2.21 I Acyl-ACP thioesterase
HNKEEIEE_01347 1.5e-217 EGP Major facilitator Superfamily
HNKEEIEE_01348 7.5e-203 EGP Major facilitator Superfamily
HNKEEIEE_01349 3e-151 K Bacterial regulatory helix-turn-helix protein, lysR family
HNKEEIEE_01350 2.4e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HNKEEIEE_01351 3.1e-248 NT Chemoreceptor zinc-binding domain
HNKEEIEE_01352 3.9e-127 S Putative adhesin
HNKEEIEE_01353 4.3e-95 S Protein of unknown function (DUF1700)
HNKEEIEE_01354 4.8e-54 K PadR family transcriptional regulator
HNKEEIEE_01355 2.8e-180 NT chemotaxis protein
HNKEEIEE_01356 1.2e-26 S Protein of unknown function (DUF3006)
HNKEEIEE_01357 1.2e-239 L Metallo-beta-lactamase superfamily
HNKEEIEE_01358 1.6e-64 S Protein of unknown function (DUF1648)
HNKEEIEE_01359 6.6e-65 yjbR S YjbR
HNKEEIEE_01360 9.4e-178 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HNKEEIEE_01361 6e-67 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HNKEEIEE_01362 1.6e-140 S HIRAN domain
HNKEEIEE_01363 1.8e-161 S HipA-like C-terminal domain
HNKEEIEE_01364 1.7e-162 yjfC O Predicted Zn-dependent protease (DUF2268)
HNKEEIEE_01365 4.7e-30 S Domain of unknown function (DUF1413)
HNKEEIEE_01366 2.9e-151
HNKEEIEE_01367 2.4e-167
HNKEEIEE_01368 3.5e-100
HNKEEIEE_01369 9.7e-91 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
HNKEEIEE_01370 3.3e-207 L COG3547 Transposase and inactivated derivatives
HNKEEIEE_01371 0.0 L Domain of unknown function (DUF4277)
HNKEEIEE_01372 1.5e-132 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HNKEEIEE_01373 9.1e-90 yebE S UPF0316 protein
HNKEEIEE_01374 2e-29 yebG S NETI protein
HNKEEIEE_01375 3.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HNKEEIEE_01376 9.3e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HNKEEIEE_01377 4.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNKEEIEE_01378 4.6e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HNKEEIEE_01379 7.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNKEEIEE_01380 3.8e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNKEEIEE_01381 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNKEEIEE_01382 4.2e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HNKEEIEE_01383 1.6e-191 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HNKEEIEE_01384 1.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HNKEEIEE_01385 1.5e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HNKEEIEE_01386 2.4e-234 purD 6.3.4.13 F Belongs to the GARS family
HNKEEIEE_01387 3.2e-36 S Protein of unknown function (DUF2892)
HNKEEIEE_01388 0.0 yerA 3.5.4.2 F adenine deaminase
HNKEEIEE_01389 8.4e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
HNKEEIEE_01390 3.7e-54 yerC S protein conserved in bacteria
HNKEEIEE_01391 5.7e-129 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HNKEEIEE_01392 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HNKEEIEE_01393 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HNKEEIEE_01394 1e-215 camS S COG4851 Protein involved in sex pheromone biosynthesis
HNKEEIEE_01395 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
HNKEEIEE_01396 1.4e-245 aceA 4.1.3.1 C Isocitrate lyase
HNKEEIEE_01397 4.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNKEEIEE_01398 2.1e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HNKEEIEE_01399 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNKEEIEE_01402 4.8e-150 Q N-acetyltransferase
HNKEEIEE_01403 9.3e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HNKEEIEE_01404 1.1e-267 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNKEEIEE_01405 1.7e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNKEEIEE_01406 2e-10
HNKEEIEE_01407 1.2e-146 ubiE Q Methyltransferase type 11
HNKEEIEE_01408 3.6e-210 M Glycosyl hydrolases family 25
HNKEEIEE_01409 2.8e-168 yfhF S nucleoside-diphosphate sugar epimerase
HNKEEIEE_01410 1.8e-158 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HNKEEIEE_01411 1.1e-84 thiW S Thiamine-precursor transporter protein (ThiW)
HNKEEIEE_01412 5.1e-40 yjhE S Phage tail protein
HNKEEIEE_01413 1.7e-145 hel M 5'-nucleotidase, lipoprotein e(P4)
HNKEEIEE_01416 5.5e-214 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HNKEEIEE_01417 2.5e-35 K ArsR family transcriptional regulator
HNKEEIEE_01418 7.2e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNKEEIEE_01419 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HNKEEIEE_01420 4.7e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HNKEEIEE_01421 1.9e-200 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
HNKEEIEE_01422 6.3e-182 K Transcriptional regulator
HNKEEIEE_01424 5.1e-32 S Cold-inducible protein YdjO
HNKEEIEE_01425 1.5e-14
HNKEEIEE_01427 1.8e-164 cvfB S protein conserved in bacteria
HNKEEIEE_01428 2e-70 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNKEEIEE_01429 1.8e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HNKEEIEE_01430 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HNKEEIEE_01431 2.8e-274 yusP P Major facilitator superfamily
HNKEEIEE_01432 5e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HNKEEIEE_01433 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HNKEEIEE_01434 4.3e-124 gntR1 K transcriptional
HNKEEIEE_01435 3.7e-171 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HNKEEIEE_01436 2.6e-216 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HNKEEIEE_01437 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HNKEEIEE_01438 3.2e-168 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HNKEEIEE_01439 1.1e-115 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HNKEEIEE_01440 1.3e-207 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HNKEEIEE_01441 4.9e-125 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNKEEIEE_01442 2.4e-259 yfnA E amino acid
HNKEEIEE_01443 1.2e-154 degV S protein conserved in bacteria
HNKEEIEE_01444 1.4e-259 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HNKEEIEE_01445 1.2e-131 comFC S Phosphoribosyl transferase domain
HNKEEIEE_01446 1.7e-69 yvyF S flagellar protein
HNKEEIEE_01447 6.7e-38 flgM KNU Negative regulator of flagellin synthesis
HNKEEIEE_01448 2.6e-77 flgN NOU FlgN protein
HNKEEIEE_01449 8.4e-234 flgK N flagellar hook-associated protein
HNKEEIEE_01450 5.2e-159 flgL N Belongs to the bacterial flagellin family
HNKEEIEE_01451 7e-80 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HNKEEIEE_01452 1.7e-35 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HNKEEIEE_01453 3.7e-154 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNKEEIEE_01455 0.0 ycbZ 3.4.21.53 O AAA domain
HNKEEIEE_01457 3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HNKEEIEE_01459 3e-60 flaG N flagellar protein FlaG
HNKEEIEE_01460 1.6e-235 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HNKEEIEE_01461 1.6e-67 fliS N flagellar protein FliS
HNKEEIEE_01462 1.3e-54 fliT S bacterial-type flagellum organization
HNKEEIEE_01463 1.6e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HNKEEIEE_01464 5e-307 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HNKEEIEE_01465 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNKEEIEE_01466 3.2e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HNKEEIEE_01467 4.2e-158 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HNKEEIEE_01468 5.5e-50 cccB C COG2010 Cytochrome c, mono- and diheme variants
HNKEEIEE_01471 7.1e-124 ftsE D cell division ATP-binding protein FtsE
HNKEEIEE_01472 1.4e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HNKEEIEE_01473 6.5e-97 D peptidase
HNKEEIEE_01474 2.4e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNKEEIEE_01475 2.1e-249 metY 2.5.1.49 E O-acetylhomoserine
HNKEEIEE_01476 3.3e-183 1.1.1.3 E homoserine dehydrogenase
HNKEEIEE_01477 1.2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HNKEEIEE_01478 3.1e-223 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNKEEIEE_01479 9.4e-167 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNKEEIEE_01480 8.8e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNKEEIEE_01481 5.6e-138 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HNKEEIEE_01482 1.7e-176 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HNKEEIEE_01483 2.8e-134
HNKEEIEE_01484 8.4e-32 S Family of unknown function (DUF5316)
HNKEEIEE_01485 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HNKEEIEE_01486 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNKEEIEE_01487 4.4e-67 S Family of unknown function (DUF5316)
HNKEEIEE_01490 1.6e-08
HNKEEIEE_01491 4e-08
HNKEEIEE_01494 8.6e-41 S Domain of unknown function (DUF4352)
HNKEEIEE_01496 2e-61 S Streptococcus thermophilus bacteriophage Gp111 protein
HNKEEIEE_01497 4.1e-84
HNKEEIEE_01498 6.8e-07
HNKEEIEE_01500 1.6e-72 ampD 3.5.1.104, 3.5.1.28 M family 25
HNKEEIEE_01501 3e-21 S SPP1 phage holin
HNKEEIEE_01502 2.4e-40
HNKEEIEE_01505 6.5e-11 S Domain of unknown function (DUF2479)
HNKEEIEE_01507 9.5e-110 S Phage minor structural protein
HNKEEIEE_01508 2.1e-225 S Phage tail protein
HNKEEIEE_01509 0.0 M phage tail tape measure protein
HNKEEIEE_01510 2.5e-44 S Psort location Cytoplasmic, score 8.87
HNKEEIEE_01511 8.5e-102 S Phage tail tube protein
HNKEEIEE_01513 5.8e-08
HNKEEIEE_01514 3.2e-45 S Phage head-tail joining protein
HNKEEIEE_01515 1.8e-50 L Phage gp6-like head-tail connector protein
HNKEEIEE_01516 3.3e-228 S Phage capsid family
HNKEEIEE_01517 1.9e-87 clpP 3.4.21.92 OU ATP-dependent Clp protease proteolytic subunit
HNKEEIEE_01518 2.2e-83 S portal protein
HNKEEIEE_01519 4.2e-301 S Terminase
HNKEEIEE_01520 1.4e-59 L phage terminase small subunit
HNKEEIEE_01521 4.1e-56 V HNH nucleases
HNKEEIEE_01523 2.1e-77 wecC 1.1.1.336 M UDP-N-acetyl-D-mannosamine dehydrogenase activity
HNKEEIEE_01525 1.2e-43 S protein conserved in bacteria
HNKEEIEE_01530 1.2e-14 S YopX protein
HNKEEIEE_01533 1.3e-16
HNKEEIEE_01538 7.6e-41 S Protein of unknown function (DUF1064)
HNKEEIEE_01540 1.1e-45 ssb L Single-strand binding protein family
HNKEEIEE_01541 3e-33 S endonuclease activity
HNKEEIEE_01542 2.3e-27
HNKEEIEE_01543 1.1e-159 dnaB 3.6.4.12 L DnaB-like helicase N terminal domain
HNKEEIEE_01544 4.9e-30 L DnaD domain protein
HNKEEIEE_01545 8.1e-25
HNKEEIEE_01546 8.5e-67 S Bacteriophage Mu Gam like protein
HNKEEIEE_01547 1.2e-21
HNKEEIEE_01553 6.5e-113 kilA K BRO family, N-terminal domain protein
HNKEEIEE_01554 2.6e-20 cro K Helix-turn-helix XRE-family like proteins
HNKEEIEE_01555 3.2e-78 3.4.21.88 K Peptidase S24-like
HNKEEIEE_01556 1.4e-129 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
HNKEEIEE_01557 8.4e-190 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNKEEIEE_01558 3.4e-200 adhC 1.1.1.1 C Zinc-binding dehydrogenase
HNKEEIEE_01564 8.7e-08
HNKEEIEE_01571 1e-276 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
HNKEEIEE_01572 4.7e-308 yhcA5 EGP Major facilitator Superfamily
HNKEEIEE_01573 1.4e-108 emrA V COG1566 Multidrug resistance efflux pump
HNKEEIEE_01574 9.3e-69 K helix_turn_helix multiple antibiotic resistance protein
HNKEEIEE_01575 8.7e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HNKEEIEE_01576 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNKEEIEE_01577 5.3e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNKEEIEE_01578 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HNKEEIEE_01579 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HNKEEIEE_01580 3.6e-60 yrzD S Post-transcriptional regulator
HNKEEIEE_01581 3.9e-271 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNKEEIEE_01582 5.4e-105 yrbG S membrane
HNKEEIEE_01583 7.6e-62 yrzE S Protein of unknown function (DUF3792)
HNKEEIEE_01584 7.9e-44 yajC U Preprotein translocase subunit YajC
HNKEEIEE_01585 6.2e-218 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HNKEEIEE_01586 2.2e-193 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HNKEEIEE_01587 5.4e-27 yrzS S Protein of unknown function (DUF2905)
HNKEEIEE_01588 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HNKEEIEE_01589 1.7e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HNKEEIEE_01590 4.5e-129 yebC K transcriptional regulatory protein
HNKEEIEE_01591 4.6e-83 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
HNKEEIEE_01592 8.4e-67 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
HNKEEIEE_01593 3.8e-144 safA M spore coat assembly protein SafA
HNKEEIEE_01594 3.5e-97 niaR S small molecule binding protein (contains 3H domain)
HNKEEIEE_01595 2.4e-158 pheA 4.2.1.51 E Prephenate dehydratase
HNKEEIEE_01596 9e-75 pheB 5.4.99.5 S Belongs to the UPF0735 family
HNKEEIEE_01597 4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HNKEEIEE_01598 2.3e-98 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HNKEEIEE_01599 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HNKEEIEE_01600 1.3e-51 ysxB J ribosomal protein
HNKEEIEE_01601 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HNKEEIEE_01602 8.1e-266 rng J ribonuclease, Rne Rng family
HNKEEIEE_01603 3.3e-158 spoIVFB S Stage IV sporulation protein
HNKEEIEE_01604 2.4e-133 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HNKEEIEE_01605 1.5e-144 minD D Belongs to the ParA family
HNKEEIEE_01606 1.4e-119 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HNKEEIEE_01607 9e-87 mreD M shape-determining protein
HNKEEIEE_01608 6.2e-141 mreC M Involved in formation and maintenance of cell shape
HNKEEIEE_01609 4.8e-185 mreB D Rod shape-determining protein MreB
HNKEEIEE_01610 1.3e-122 radC E Belongs to the UPF0758 family
HNKEEIEE_01612 1.5e-162 spoIIB
HNKEEIEE_01613 3.8e-142 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HNKEEIEE_01614 5.4e-103
HNKEEIEE_01615 1.3e-90 pilN NU PFAM Fimbrial assembly family protein
HNKEEIEE_01616 4.1e-181 NU COG4972 Tfp pilus assembly protein, ATPase PilM
HNKEEIEE_01617 1.4e-24 NU Prokaryotic N-terminal methylation motif
HNKEEIEE_01619 1.8e-202 pilC NU type II secretion system
HNKEEIEE_01620 9e-195 pilT NU twitching motility protein
HNKEEIEE_01621 6.2e-291 pilB NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNKEEIEE_01622 8.4e-196 V G5
HNKEEIEE_01623 1e-120 S PRC-barrel domain
HNKEEIEE_01624 4.6e-134
HNKEEIEE_01625 2.1e-201 NU Pilus assembly protein PilX
HNKEEIEE_01626 1.8e-76
HNKEEIEE_01628 1.1e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HNKEEIEE_01629 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HNKEEIEE_01630 9.5e-26
HNKEEIEE_01631 1.1e-192 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNKEEIEE_01632 4.9e-214 spoVID M stage VI sporulation protein D
HNKEEIEE_01633 3.5e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HNKEEIEE_01634 7.1e-186 hemB 4.2.1.24 H Belongs to the ALAD family
HNKEEIEE_01635 7.6e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HNKEEIEE_01636 2.4e-167 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HNKEEIEE_01637 2.5e-147 hemX O cytochrome C
HNKEEIEE_01638 1.6e-241 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HNKEEIEE_01639 4.5e-88 ysxD
HNKEEIEE_01640 4.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HNKEEIEE_01641 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HNKEEIEE_01642 6.5e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HNKEEIEE_01643 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HNKEEIEE_01644 8.4e-211 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HNKEEIEE_01645 6.8e-184 trxA2 O COG0457 FOG TPR repeat
HNKEEIEE_01646 2.4e-72 S Protein of unknown function (DUF2512)
HNKEEIEE_01647 7.5e-46
HNKEEIEE_01649 3.7e-93 ysnB S Phosphoesterase
HNKEEIEE_01650 6.6e-105 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNKEEIEE_01651 2.3e-190 gerM S COG5401 Spore germination protein
HNKEEIEE_01653 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HNKEEIEE_01654 3.9e-78 ysmB 2.4.2.28 K transcriptional
HNKEEIEE_01655 1.9e-84 S GDYXXLXY protein
HNKEEIEE_01656 2e-189 S Predicted membrane protein (DUF2157)
HNKEEIEE_01658 2.3e-31 gerE K Transcriptional regulator
HNKEEIEE_01659 2.3e-89 ysmA S thioesterase
HNKEEIEE_01660 2.9e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HNKEEIEE_01661 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HNKEEIEE_01662 2.5e-104 sdhC C succinate dehydrogenase
HNKEEIEE_01663 2.3e-78 yslB S Protein of unknown function (DUF2507)
HNKEEIEE_01664 2e-222 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HNKEEIEE_01665 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HNKEEIEE_01666 5.1e-53 trxA O Belongs to the thioredoxin family
HNKEEIEE_01667 7.4e-175 etfA C Electron transfer flavoprotein
HNKEEIEE_01668 4.8e-129 etfB C Electron transfer flavoprotein
HNKEEIEE_01669 4.4e-138 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HNKEEIEE_01670 6e-103 fadR K Transcriptional regulator
HNKEEIEE_01671 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HNKEEIEE_01672 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNKEEIEE_01673 0.0 polX L COG1796 DNA polymerase IV (family X)
HNKEEIEE_01674 6.4e-88 cvpA S membrane protein, required for colicin V production
HNKEEIEE_01675 7.3e-46 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HNKEEIEE_01676 1.8e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNKEEIEE_01677 1.6e-171 S Nuclease-related domain
HNKEEIEE_01678 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNKEEIEE_01679 9.6e-181 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNKEEIEE_01680 8.9e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNKEEIEE_01681 2.2e-31 sspI S Belongs to the SspI family
HNKEEIEE_01682 2.3e-116
HNKEEIEE_01683 1.2e-29 sidE D nuclear chromosome segregation
HNKEEIEE_01684 2.6e-121 M1-1017 S Protein of unknown function (DUF1129)
HNKEEIEE_01685 1.8e-56 K Transcriptional regulator
HNKEEIEE_01686 2.3e-11 S NADPH-dependent FMN reductase
HNKEEIEE_01687 1.3e-127 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HNKEEIEE_01688 1.5e-177 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNKEEIEE_01689 1.1e-101 yieF S NAD(P)H-dependent FMN reductase
HNKEEIEE_01690 8.1e-37 ypdE 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNKEEIEE_01691 4.6e-50 ypdE 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HNKEEIEE_01692 3.3e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HNKEEIEE_01697 1.6e-08
HNKEEIEE_01705 2.3e-92 ydcK S Belongs to the SprT family
HNKEEIEE_01706 0.0 yhgF K COG2183 Transcriptional accessory protein
HNKEEIEE_01707 5.2e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HNKEEIEE_01708 3.7e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNKEEIEE_01709 1.5e-80 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HNKEEIEE_01710 4e-54 rsbV T Belongs to the anti-sigma-factor antagonist family
HNKEEIEE_01711 6.9e-195 rsbU 3.1.3.3 KT phosphatase
HNKEEIEE_01712 2e-70 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HNKEEIEE_01713 8.1e-55 rsbS T antagonist
HNKEEIEE_01714 8.8e-153 rsbR T Positive regulator of sigma-B
HNKEEIEE_01715 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HNKEEIEE_01716 0.0 metH 2.1.1.13 E Methionine synthase
HNKEEIEE_01718 1.2e-09 csbD S Belongs to the UPF0337 (CsbD) family
HNKEEIEE_01720 1.5e-88 K ComK protein
HNKEEIEE_01721 2.4e-96 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
HNKEEIEE_01722 3.1e-150 E lipolytic protein G-D-S-L family
HNKEEIEE_01723 1.1e-122 ywqC M biosynthesis protein
HNKEEIEE_01724 6.8e-112 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HNKEEIEE_01725 7.9e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HNKEEIEE_01726 7.5e-150 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HNKEEIEE_01727 2.4e-79 rfbP 2.7.8.6 M Bacterial sugar transferase
HNKEEIEE_01728 4.4e-92 rfbN GT2 S Glycosyltransferase like family 2
HNKEEIEE_01729 1.5e-112 S Glycosyltransferase WbsX
HNKEEIEE_01730 8.8e-55 cps2I M Glycosyl transferases group 1
HNKEEIEE_01731 3.2e-63 S Glycosyltransferase like family 2
HNKEEIEE_01732 2.4e-142 S polysaccharide biosynthetic process
HNKEEIEE_01733 1.9e-42
HNKEEIEE_01734 6.9e-156 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HNKEEIEE_01735 4.1e-85 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HNKEEIEE_01736 1.3e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HNKEEIEE_01737 2.2e-201 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HNKEEIEE_01738 2e-255 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNKEEIEE_01739 1.4e-87 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNKEEIEE_01740 8e-17 3.2.1.96 M cysteine-type peptidase activity
HNKEEIEE_01741 2.4e-228 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HNKEEIEE_01743 1.9e-29 yodI
HNKEEIEE_01744 3.9e-150 yjaZ O Zn-dependent protease
HNKEEIEE_01745 3.5e-80 yodH Q Methyltransferase
HNKEEIEE_01746 1.1e-124 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNKEEIEE_01747 4e-130 K Helix-turn-helix domain
HNKEEIEE_01748 5.7e-36 yqgY S Protein of unknown function (DUF2626)
HNKEEIEE_01749 5e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HNKEEIEE_01750 1.4e-20 yqgW S Protein of unknown function (DUF2759)
HNKEEIEE_01751 3.5e-169 glcK 2.7.1.2 G Glucokinase
HNKEEIEE_01752 3.3e-30 yqgQ S protein conserved in bacteria
HNKEEIEE_01753 1.8e-201 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HNKEEIEE_01755 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HNKEEIEE_01756 1.1e-187 yraQ S Predicted permease
HNKEEIEE_01758 1.4e-133 T Calcineurin-like phosphoesterase superfamily domain
HNKEEIEE_01759 1.1e-192 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
HNKEEIEE_01760 7.8e-199 selU S tRNA 2-selenouridine synthase
HNKEEIEE_01762 7.7e-129 IQ Enoyl-(Acyl carrier protein) reductase
HNKEEIEE_01763 1.9e-80 I N-terminal half of MaoC dehydratase
HNKEEIEE_01764 1.1e-71 I MaoC like domain
HNKEEIEE_01765 3.6e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HNKEEIEE_01766 1.4e-37 S Protein of unknown function (DUF1450)
HNKEEIEE_01767 1.8e-79 S Protein of unknown function (DUF1189)
HNKEEIEE_01768 1.8e-167 murB 1.3.1.98 M cell wall formation
HNKEEIEE_01769 6.3e-57
HNKEEIEE_01770 2.8e-171 ydbJ V ABC transporter, ATP-binding protein
HNKEEIEE_01771 1.6e-171 yhcI S ABC-2 family transporter protein
HNKEEIEE_01772 1.7e-81 V VanZ like family
HNKEEIEE_01773 1.6e-76 dps P Ferritin-like domain
HNKEEIEE_01774 7.6e-228 mntH P H( )-stimulated, divalent metal cation uptake system
HNKEEIEE_01775 3.7e-119 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HNKEEIEE_01776 2.1e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HNKEEIEE_01777 1.9e-81 Q protein disulfide oxidoreductase activity
HNKEEIEE_01778 7.3e-21 S YpzG-like protein
HNKEEIEE_01779 1.2e-193 G Glycosyl hydrolases family 15
HNKEEIEE_01780 3.3e-30 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HNKEEIEE_01781 5.7e-307 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HNKEEIEE_01782 1.2e-208 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HNKEEIEE_01783 1.4e-185 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HNKEEIEE_01784 1.8e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HNKEEIEE_01785 1.5e-155 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HNKEEIEE_01786 7.8e-148 xth 3.1.11.2 L exodeoxyribonuclease III
HNKEEIEE_01787 2.4e-77 sleB 3.5.1.28 M Cell wall
HNKEEIEE_01788 1.4e-215 fsr P COG0477 Permeases of the major facilitator superfamily
HNKEEIEE_01789 1.3e-131 IQ Enoyl-(Acyl carrier protein) reductase
HNKEEIEE_01790 5.9e-180 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
HNKEEIEE_01791 5.6e-75 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNKEEIEE_01792 9e-60
HNKEEIEE_01793 8.4e-105 yozB S membrane
HNKEEIEE_01794 6.1e-143 S Sucrose-6F-phosphate phosphohydrolase
HNKEEIEE_01795 7.3e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HNKEEIEE_01796 2.5e-291 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HNKEEIEE_01797 5.4e-209 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
HNKEEIEE_01798 9.2e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HNKEEIEE_01799 4.4e-25 sspH S small acid-soluble spore protein
HNKEEIEE_01800 4e-104 S Appr-1'-p processing enzyme
HNKEEIEE_01801 9.1e-56 I SCP-2 sterol transfer family
HNKEEIEE_01802 3.9e-192 S COG0491 Zn-dependent hydrolases, including glyoxylases
HNKEEIEE_01803 2.1e-183 kefA M Mechanosensitive ion channel
HNKEEIEE_01804 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HNKEEIEE_01805 8.6e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HNKEEIEE_01806 6.9e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HNKEEIEE_01807 2.9e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HNKEEIEE_01808 3.1e-189 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HNKEEIEE_01809 3.8e-179 yjlA EG Putative multidrug resistance efflux transporter
HNKEEIEE_01810 1.6e-271 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
HNKEEIEE_01811 1e-120 mta K transcriptional
HNKEEIEE_01812 4.8e-108
HNKEEIEE_01813 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HNKEEIEE_01814 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNKEEIEE_01815 7.2e-132 comB 3.1.3.71 H Belongs to the ComB family
HNKEEIEE_01816 6.3e-139 yitD 4.4.1.19 S synthase
HNKEEIEE_01817 2.3e-74 S Glyoxalase bleomycin resistance protein dioxygenase
HNKEEIEE_01818 1.6e-177 nrtA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HNKEEIEE_01819 4.8e-137 thiX 2.7.1.50 P binding-protein-dependent transport systems inner membrane component
HNKEEIEE_01824 1.7e-07
HNKEEIEE_01825 1.5e-07
HNKEEIEE_01827 5.4e-75 P nitrite transmembrane transporter activity
HNKEEIEE_01829 4.1e-13
HNKEEIEE_01830 3.7e-128 fecE 3.6.3.34 HP ABC transporter
HNKEEIEE_01831 8.3e-93 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HNKEEIEE_01832 2.9e-251 L PFAM transposase IS4 family protein
HNKEEIEE_01833 6.3e-60 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HNKEEIEE_01834 1e-10 ybxH S Family of unknown function (DUF5370)
HNKEEIEE_01835 1.5e-08
HNKEEIEE_01836 4.6e-171 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNKEEIEE_01837 5.3e-63 argO S LysE type translocator
HNKEEIEE_01838 3.4e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNKEEIEE_01839 1.2e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HNKEEIEE_01840 1.5e-83 S AAA domain
HNKEEIEE_01841 9.4e-86 S Bacterial PH domain
HNKEEIEE_01842 9.4e-275 ydbT S Bacterial PH domain
HNKEEIEE_01843 3.3e-75 yqgC S protein conserved in bacteria
HNKEEIEE_01844 1.3e-236 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNKEEIEE_01845 9.5e-43
HNKEEIEE_01846 1.1e-70 yoaS S Protein of unknown function (DUF2975)
HNKEEIEE_01847 5.1e-28 yozG K Transcriptional regulator
HNKEEIEE_01848 2.4e-145 yoaT S Protein of unknown function (DUF817)
HNKEEIEE_01849 1.7e-158 NT chemotaxis protein
HNKEEIEE_01850 1.3e-260 S Protein of unknown function (DUF2397)
HNKEEIEE_01852 3e-231 S Protein of unknown function (DUF2398)
HNKEEIEE_01853 0.0 D Putative exonuclease SbcCD, C subunit
HNKEEIEE_01854 1.7e-251 S Protein of unknown function N-terminus (DUF3323)
HNKEEIEE_01855 3.5e-220 yhgE S YhgE Pip N-terminal domain protein
HNKEEIEE_01856 6.3e-105 yhgD K Transcriptional regulator
HNKEEIEE_01857 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HNKEEIEE_01858 1.6e-193 ansA 3.5.1.1 EJ L-asparaginase
HNKEEIEE_01859 1.5e-308 ypdA 2.7.13.3 T Signal transduction histidine kinase
HNKEEIEE_01860 2.1e-137 ypdB KT LytTr DNA-binding domain
HNKEEIEE_01861 3.1e-218 yhjX P Major facilitator superfamily
HNKEEIEE_01862 1.4e-217 yxjG 2.1.1.14 E Methionine synthase
HNKEEIEE_01863 4.4e-104 yetJ S Belongs to the BI1 family
HNKEEIEE_01864 2.6e-43 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HNKEEIEE_01865 4.4e-75 V CAAX protease self-immunity
HNKEEIEE_01866 8.8e-63 EGP Major facilitator Superfamily
HNKEEIEE_01867 1.4e-27 K Helix-turn-helix domain
HNKEEIEE_01868 4.7e-31
HNKEEIEE_01869 2.7e-31 S Domain of unknown function (DUF4177)
HNKEEIEE_01870 5.3e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HNKEEIEE_01872 2e-152 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HNKEEIEE_01873 1.6e-282 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNKEEIEE_01874 1.6e-105 pncA Q COG1335 Amidases related to nicotinamidase
HNKEEIEE_01875 6.1e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HNKEEIEE_01876 0.0 ykoS
HNKEEIEE_01877 6.6e-187 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HNKEEIEE_01878 4.1e-68 yngA S GtrA-like protein
HNKEEIEE_01879 9.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HNKEEIEE_01880 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HNKEEIEE_01881 6.4e-123 ydiL S CAAX protease self-immunity
HNKEEIEE_01882 4.7e-28 S Domain of unknown function (DUF4305)
HNKEEIEE_01883 5.1e-131 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNKEEIEE_01884 4.6e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HNKEEIEE_01885 1.1e-09 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HNKEEIEE_01886 0.0 ydiF S ABC transporter
HNKEEIEE_01887 8.1e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNKEEIEE_01888 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HNKEEIEE_01889 1.7e-128 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HNKEEIEE_01890 4e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HNKEEIEE_01892 8.4e-57 S protein conserved in bacteria
HNKEEIEE_01893 2.4e-30 P Copper resistance protein CopZ
HNKEEIEE_01894 0.0 copA 3.6.3.54 P P-type ATPase
HNKEEIEE_01895 1.2e-59 EGP Major facilitator Superfamily
HNKEEIEE_01896 2.4e-166 S Protein of unknown function (DUF1646)
HNKEEIEE_01897 9.3e-116 sapB S MgtC SapB transporter
HNKEEIEE_01898 2.2e-149 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HNKEEIEE_01899 1.4e-26
HNKEEIEE_01900 9.2e-233 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
HNKEEIEE_01902 4.4e-29 K Helix-turn-helix XRE-family like proteins
HNKEEIEE_01903 8.3e-55 yqzD
HNKEEIEE_01904 0.0 mrdA 3.4.16.4 M penicillin-binding protein
HNKEEIEE_01905 9.4e-220 yqgE EGP Major facilitator superfamily
HNKEEIEE_01906 3.7e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HNKEEIEE_01907 3.4e-55 fimV NU Tfp pilus assembly protein FimV
HNKEEIEE_01908 1.8e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HNKEEIEE_01909 2.7e-111 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HNKEEIEE_01910 2.2e-75 zur P Belongs to the Fur family
HNKEEIEE_01911 1.6e-141 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HNKEEIEE_01912 1.3e-142 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HNKEEIEE_01913 1e-19 yqfT S Protein of unknown function (DUF2624)
HNKEEIEE_01914 1.3e-132 cwlO CBM50 M protein conserved in bacteria
HNKEEIEE_01915 3.9e-170 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HNKEEIEE_01916 4.7e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HNKEEIEE_01918 9.8e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HNKEEIEE_01919 2e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HNKEEIEE_01920 9e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HNKEEIEE_01921 1.5e-64 cccA C Cytochrome C oxidase, cbb3-type, subunit III
HNKEEIEE_01922 4.6e-86
HNKEEIEE_01923 2.8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HNKEEIEE_01924 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HNKEEIEE_01925 1.6e-146 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HNKEEIEE_01926 3.4e-112 ccpN K CBS domain
HNKEEIEE_01927 1.6e-145 recO L Involved in DNA repair and RecF pathway recombination
HNKEEIEE_01928 6.7e-08 S YqzL-like protein
HNKEEIEE_01929 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNKEEIEE_01930 7.9e-67 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HNKEEIEE_01931 4.2e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HNKEEIEE_01932 0.0 yqfF S membrane-associated HD superfamily hydrolase
HNKEEIEE_01933 6.1e-174 phoH T Phosphate starvation-inducible protein PhoH
HNKEEIEE_01934 1.2e-224 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HNKEEIEE_01935 3.2e-46 yqfC S sporulation protein YqfC
HNKEEIEE_01936 6.6e-70 yqeY S Yqey-like protein
HNKEEIEE_01937 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HNKEEIEE_01938 2.6e-48 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HNKEEIEE_01939 1.5e-156 yqeW P COG1283 Na phosphate symporter
HNKEEIEE_01940 4.2e-261 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HNKEEIEE_01941 2.7e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HNKEEIEE_01942 5.1e-173 prmA J Methylates ribosomal protein L11
HNKEEIEE_01943 3.8e-207 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HNKEEIEE_01944 5.6e-309 dnaK O Heat shock 70 kDa protein
HNKEEIEE_01945 3.8e-90 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HNKEEIEE_01946 8.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HNKEEIEE_01947 3e-220 hemN H Involved in the biosynthesis of porphyrin-containing compound
HNKEEIEE_01948 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HNKEEIEE_01949 3.8e-221 spoIIP M stage II sporulation protein P
HNKEEIEE_01950 1.2e-202 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HNKEEIEE_01951 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HNKEEIEE_01952 1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
HNKEEIEE_01953 1.1e-07 S YqzM-like protein
HNKEEIEE_01954 0.0 comEC S Competence protein ComEC
HNKEEIEE_01955 6.5e-113 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
HNKEEIEE_01956 1.2e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HNKEEIEE_01957 2.9e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNKEEIEE_01958 2.5e-146 cmoA S Methyltransferase domain
HNKEEIEE_01959 1.1e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HNKEEIEE_01960 3.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HNKEEIEE_01961 5e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HNKEEIEE_01962 3.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HNKEEIEE_01963 4.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HNKEEIEE_01964 1.7e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HNKEEIEE_01965 2.6e-94 yqeG S hydrolase of the HAD superfamily
HNKEEIEE_01966 9.6e-258 glcF C Glycolate oxidase
HNKEEIEE_01967 1.1e-251 glcD 1.1.3.15 C Glycolate oxidase subunit
HNKEEIEE_01968 1.5e-192 ysfB KT regulator
HNKEEIEE_01969 1.9e-280 mco 1.16.3.3 Q multicopper oxidases
HNKEEIEE_01970 1.8e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
HNKEEIEE_01971 7.8e-67 perX S DsrE/DsrF-like family
HNKEEIEE_01972 2.4e-39 O Glutaredoxin
HNKEEIEE_01973 8.2e-55 P Rhodanese Homology Domain
HNKEEIEE_01974 0.0 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HNKEEIEE_01975 2.2e-31 csfB S Inhibitor of sigma-G Gin
HNKEEIEE_01976 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HNKEEIEE_01977 4.6e-132 fruR K Transcriptional regulator
HNKEEIEE_01978 5.9e-205 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HNKEEIEE_01979 3.2e-95 D Hemerythrin HHE cation binding
HNKEEIEE_01980 8.2e-32
HNKEEIEE_01981 2.5e-152 yidA S hydrolases of the HAD superfamily
HNKEEIEE_01982 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
HNKEEIEE_01983 7.8e-85 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HNKEEIEE_01984 5.1e-255 iolT EGP Major facilitator Superfamily
HNKEEIEE_01985 4.8e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HNKEEIEE_01987 3.1e-72 ywnF S Family of unknown function (DUF5392)
HNKEEIEE_01988 1.7e-134 ywaC 2.7.6.5 S protein conserved in bacteria
HNKEEIEE_01989 5.9e-255 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNKEEIEE_01990 2.3e-192 yhdN C Aldo keto reductase
HNKEEIEE_01991 2e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
HNKEEIEE_01992 5.6e-101 dhaL 2.7.1.121 S Dak2
HNKEEIEE_01993 2.2e-182 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
HNKEEIEE_01994 4.6e-175 pfoS S Phosphotransferase system, EIIC
HNKEEIEE_01995 8.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HNKEEIEE_01996 8.9e-240 E COG1113 Gamma-aminobutyrate permease and related permeases
HNKEEIEE_01997 3.3e-167 ytnM S membrane transporter protein
HNKEEIEE_01998 4.5e-228 ywdJ F Xanthine uracil
HNKEEIEE_01999 0.0 yjcD 3.6.4.12 L DNA helicase
HNKEEIEE_02000 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNKEEIEE_02001 7.4e-109 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
HNKEEIEE_02002 5.7e-10 S transposase or invertase
HNKEEIEE_02003 5e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HNKEEIEE_02004 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HNKEEIEE_02005 3.4e-143 est 3.1.1.1 S Carboxylesterase
HNKEEIEE_02006 2.5e-28 secG U Preprotein translocase subunit SecG
HNKEEIEE_02007 5.4e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNKEEIEE_02009 3.8e-303 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HNKEEIEE_02010 1.1e-122 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HNKEEIEE_02011 8.3e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HNKEEIEE_02012 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HNKEEIEE_02013 1.5e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HNKEEIEE_02014 7e-41 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HNKEEIEE_02015 1.9e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HNKEEIEE_02017 1.3e-07 S Heavy-metal-associated domain
HNKEEIEE_02018 2.2e-85 S Protein of unknown function (DUF1641)
HNKEEIEE_02020 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HNKEEIEE_02021 1.7e-31
HNKEEIEE_02023 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNKEEIEE_02024 1.4e-84 uspF T Universal stress protein
HNKEEIEE_02026 1.8e-192 ykfD E Belongs to the ABC transporter superfamily
HNKEEIEE_02027 1e-178 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HNKEEIEE_02028 0.0 dppE E ABC transporter substrate-binding protein
HNKEEIEE_02029 9.3e-189 dppD P Belongs to the ABC transporter superfamily
HNKEEIEE_02030 1.5e-167 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNKEEIEE_02031 9.8e-161 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNKEEIEE_02032 1.3e-128 S Peptidase C26
HNKEEIEE_02033 2.2e-184 corA P Mediates influx of magnesium ions
HNKEEIEE_02034 1.8e-46 yhdB S YhdB-like protein
HNKEEIEE_02035 4.9e-162 3.5.1.4 J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases
HNKEEIEE_02036 5.3e-275 ycgB S Stage V sporulation protein R
HNKEEIEE_02037 1.4e-184 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HNKEEIEE_02038 5.9e-134 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
HNKEEIEE_02039 1.2e-73 bdbC O Required for disulfide bond formation in some proteins
HNKEEIEE_02040 5.8e-88 bdbA CO Thioredoxin
HNKEEIEE_02041 3.5e-67 yhcU S Family of unknown function (DUF5365)
HNKEEIEE_02042 1.2e-10 yhcU S Family of unknown function (DUF5365)
HNKEEIEE_02043 5.6e-112 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HNKEEIEE_02044 2.5e-178 pit P phosphate transporter
HNKEEIEE_02045 2.5e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
HNKEEIEE_02047 9.6e-222 yhbH S Belongs to the UPF0229 family
HNKEEIEE_02048 0.0 prkA T Ser protein kinase
HNKEEIEE_02049 2e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HNKEEIEE_02050 2.5e-161 yhbB S Putative amidase domain
HNKEEIEE_02051 1.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HNKEEIEE_02052 8.2e-103 yvbG U UPF0056 membrane protein
HNKEEIEE_02055 1.6e-08
HNKEEIEE_02056 5.1e-08
HNKEEIEE_02062 3e-09
HNKEEIEE_02071 7.2e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HNKEEIEE_02072 1.8e-256 menF 5.4.4.2 HQ Isochorismate synthase
HNKEEIEE_02073 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HNKEEIEE_02074 7.7e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HNKEEIEE_02075 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HNKEEIEE_02076 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HNKEEIEE_02077 4.7e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HNKEEIEE_02078 2.1e-23 S Domain of Unknown Function (DUF1540)
HNKEEIEE_02079 2.7e-160 adcA P Belongs to the bacterial solute-binding protein 9 family
HNKEEIEE_02081 1.3e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HNKEEIEE_02082 2.5e-77 dps P Belongs to the Dps family
HNKEEIEE_02083 7.4e-39
HNKEEIEE_02084 2e-85 ytkD 3.6.1.55 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HNKEEIEE_02085 4.3e-128 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HNKEEIEE_02086 6.3e-137 ytlC P ABC transporter
HNKEEIEE_02087 8.7e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HNKEEIEE_02088 1.4e-292 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HNKEEIEE_02089 2.3e-101 ywqN S NAD(P)H-dependent
HNKEEIEE_02090 1.4e-208 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HNKEEIEE_02091 1.4e-68 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
HNKEEIEE_02092 0.0 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HNKEEIEE_02093 3.2e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HNKEEIEE_02094 0.0 asnB 6.3.5.4 E Asparagine synthase
HNKEEIEE_02095 5.6e-73 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HNKEEIEE_02096 4.5e-154 ytpA 3.1.1.5 I Alpha beta hydrolase
HNKEEIEE_02097 5.7e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HNKEEIEE_02098 4.1e-101 ytqB J Putative rRNA methylase
HNKEEIEE_02100 9.4e-43 ytzC S Protein of unknown function (DUF2524)
HNKEEIEE_02101 4.6e-187 yttB EGP Major facilitator Superfamily
HNKEEIEE_02102 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HNKEEIEE_02104 2.3e-10
HNKEEIEE_02105 6.4e-27 yteV S Sporulation protein Cse60
HNKEEIEE_02106 1.2e-286 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNKEEIEE_02107 2.7e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HNKEEIEE_02108 2.9e-273 pepV 3.5.1.18 E Dipeptidase
HNKEEIEE_02109 7.8e-160 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HNKEEIEE_02111 2.8e-105 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HNKEEIEE_02112 7.6e-145 ytlQ
HNKEEIEE_02113 2e-154 ytmP 2.7.1.89 M Phosphotransferase
HNKEEIEE_02114 1e-54 ytzH S YtzH-like protein
HNKEEIEE_02115 2.3e-130 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HNKEEIEE_02116 1.8e-169 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HNKEEIEE_02117 3.3e-52 ytzB S small secreted protein
HNKEEIEE_02118 6.9e-210 T PhoQ Sensor
HNKEEIEE_02119 6.8e-23 cheR 2.1.1.80 NT chemotaxis
HNKEEIEE_02120 1.2e-195 rsbU 3.1.3.3 T response regulator
HNKEEIEE_02122 1.1e-42 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HNKEEIEE_02123 1.8e-147 ytpQ S Belongs to the UPF0354 family
HNKEEIEE_02124 2.6e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNKEEIEE_02125 1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HNKEEIEE_02126 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HNKEEIEE_02127 3e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HNKEEIEE_02128 5.2e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
HNKEEIEE_02129 1.5e-244 icd 1.1.1.42 C isocitrate
HNKEEIEE_02130 4.4e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HNKEEIEE_02131 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNKEEIEE_02132 1.7e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HNKEEIEE_02133 5.6e-107 ytaF P Probably functions as a manganese efflux pump
HNKEEIEE_02134 3.6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNKEEIEE_02135 1.9e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HNKEEIEE_02136 8.2e-90 2.3.1.178 J Benzoate transporter
HNKEEIEE_02137 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNKEEIEE_02138 1.9e-261 dnaB L Membrane attachment protein
HNKEEIEE_02139 8.4e-176 dnaI L Primosomal protein DnaI
HNKEEIEE_02140 1.7e-151 ytxC S YtxC-like family
HNKEEIEE_02141 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNKEEIEE_02142 2.1e-214 G Transmembrane secretion effector
HNKEEIEE_02143 3.9e-108 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HNKEEIEE_02144 4.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HNKEEIEE_02145 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HNKEEIEE_02146 0.0 cydD V ATP-binding protein
HNKEEIEE_02147 0.0 cydD V ATP-binding
HNKEEIEE_02148 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HNKEEIEE_02149 1.6e-260 cydA 1.10.3.14 C oxidase, subunit
HNKEEIEE_02150 1.2e-30
HNKEEIEE_02151 2.7e-137 pdaB 3.5.1.104 G xylanase chitin deacetylase
HNKEEIEE_02152 4.9e-76
HNKEEIEE_02153 6.2e-151 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HNKEEIEE_02154 5.7e-61 yojF S Protein of unknown function (DUF1806)
HNKEEIEE_02155 1.6e-128 bshB2 S deacetylase
HNKEEIEE_02156 4.4e-163 ycsE S hydrolases of the HAD superfamily
HNKEEIEE_02157 0.0 recQ 3.6.4.12 L DNA helicase
HNKEEIEE_02158 5e-232 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
HNKEEIEE_02159 6.9e-153 ybbH_2 K Transcriptional regulator
HNKEEIEE_02160 1.8e-161 S Alpha/beta hydrolase of unknown function (DUF915)
HNKEEIEE_02161 5.9e-14
HNKEEIEE_02162 5.5e-231 T His Kinase A (phosphoacceptor) domain
HNKEEIEE_02163 4.4e-126 T Two component transcriptional regulator, winged helix family
HNKEEIEE_02164 1.4e-77
HNKEEIEE_02165 1.6e-114 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNKEEIEE_02167 2.2e-117 ywbG M effector of murein hydrolase
HNKEEIEE_02168 2.9e-58 ywbH S LrgA family
HNKEEIEE_02169 1.6e-179 ywbI K Transcriptional regulator
HNKEEIEE_02170 0.0 asnO 6.3.5.4 E Asparagine synthase
HNKEEIEE_02171 3.7e-129 S Protein of unknown function (DUF1646)
HNKEEIEE_02172 3.5e-71 S Threonine/Serine exporter, ThrE
HNKEEIEE_02173 3.3e-130 thrE S Putative threonine/serine exporter
HNKEEIEE_02174 1.5e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HNKEEIEE_02175 0.0 cstA T Carbon starvation protein
HNKEEIEE_02176 1e-125 lytT T COG3279 Response regulator of the LytR AlgR family
HNKEEIEE_02177 0.0 lytS 2.7.13.3 T Histidine kinase
HNKEEIEE_02178 2.1e-154 metQ M Belongs to the nlpA lipoprotein family
HNKEEIEE_02179 4.8e-101 metI P COG2011 ABC-type metal ion transport system, permease component
HNKEEIEE_02180 3.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNKEEIEE_02181 8.3e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HNKEEIEE_02182 2.4e-101
HNKEEIEE_02183 6.3e-221 pilM NU Pilus assembly protein
HNKEEIEE_02184 3.1e-240 yisQ V Mate efflux family protein
HNKEEIEE_02185 4.5e-154 M Glycosyl transferase family 8
HNKEEIEE_02186 3.7e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HNKEEIEE_02187 8.4e-271 EGP Major facilitator Superfamily
HNKEEIEE_02188 2e-14 S Leucine-rich repeat (LRR) protein
HNKEEIEE_02189 1.3e-224 uraA F Xanthine uracil
HNKEEIEE_02190 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HNKEEIEE_02191 4.3e-124 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HNKEEIEE_02192 6.3e-278 msbA2 3.6.3.44 V ABC transporter
HNKEEIEE_02193 2.3e-111 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HNKEEIEE_02194 6.4e-98 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HNKEEIEE_02195 0.0 S MMPL domain protein
HNKEEIEE_02196 2.9e-300 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HNKEEIEE_02197 7.5e-45 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HNKEEIEE_02198 6.3e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HNKEEIEE_02199 8.9e-239 LYS1 1.5.1.7 E Saccharopine dehydrogenase
HNKEEIEE_02200 4.8e-226 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HNKEEIEE_02201 8.1e-207 S Domain of unknown function (DUF1611_N) Rossmann-like domain
HNKEEIEE_02202 5.6e-214 5.1.1.12 E Alanine racemase, N-terminal domain
HNKEEIEE_02203 4e-137 cjaA ET Belongs to the bacterial solute-binding protein 3 family
HNKEEIEE_02204 1.6e-129 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
HNKEEIEE_02205 2e-102 E amino acid ABC transporter
HNKEEIEE_02206 5.8e-115 papP E amino acid ABC transporter
HNKEEIEE_02207 1.6e-293 mqo 1.1.5.4 S malate quinone oxidoreductase
HNKEEIEE_02208 2.1e-244 kgtP EGP -transporter
HNKEEIEE_02209 5e-21 mcrB L Restriction endonuclease
HNKEEIEE_02210 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HNKEEIEE_02211 5.2e-101 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HNKEEIEE_02212 5.3e-297 hsdM 2.1.1.72 V Type I restriction-modification system
HNKEEIEE_02213 9.1e-107
HNKEEIEE_02214 1.9e-75 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HNKEEIEE_02215 3.4e-225 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNKEEIEE_02216 1.1e-147 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HNKEEIEE_02217 3.9e-142 yycI S protein conserved in bacteria
HNKEEIEE_02218 3.5e-241 yycH S protein conserved in bacteria
HNKEEIEE_02219 0.0 vicK 2.7.13.3 T Histidine kinase
HNKEEIEE_02220 1.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNKEEIEE_02224 1.9e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HNKEEIEE_02225 2.2e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HNKEEIEE_02226 4.5e-71 rplI J binds to the 23S rRNA
HNKEEIEE_02227 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HNKEEIEE_02228 4.6e-158 yybS S membrane
HNKEEIEE_02229 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HNKEEIEE_02230 2.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HNKEEIEE_02231 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HNKEEIEE_02232 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HNKEEIEE_02233 1.4e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HNKEEIEE_02234 0.0 ydaO E amino acid
HNKEEIEE_02235 3.3e-89 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HNKEEIEE_02237 1.2e-137 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HNKEEIEE_02238 3.8e-93 yvbK 3.1.3.25 K acetyltransferase
HNKEEIEE_02239 2.2e-29 VPA1573 J acetyltransferase
HNKEEIEE_02240 7.7e-73 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
HNKEEIEE_02241 4.1e-144 ykrA S hydrolases of the HAD superfamily
HNKEEIEE_02242 2.6e-84 hxlB 4.1.2.43, 5.3.1.27 M arabinose-5-phosphate isomerase activity
HNKEEIEE_02243 6.4e-176 ykvZ 5.1.1.1 K Transcriptional regulator
HNKEEIEE_02244 1.3e-70 gutA G MFS/sugar transport protein
HNKEEIEE_02245 3e-228 yfkA S YfkB-like domain
HNKEEIEE_02246 3.4e-81
HNKEEIEE_02247 3.1e-27
HNKEEIEE_02248 9.6e-71 yxiE T Belongs to the universal stress protein A family
HNKEEIEE_02249 6.9e-224 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HNKEEIEE_02250 1.6e-146 aacC 2.3.1.81 V aminoglycoside
HNKEEIEE_02251 1.7e-190 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HNKEEIEE_02252 7.9e-100 bioY S Biotin biosynthesis protein
HNKEEIEE_02253 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HNKEEIEE_02254 3.6e-76 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HNKEEIEE_02255 2.3e-79
HNKEEIEE_02256 7.9e-197 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HNKEEIEE_02257 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HNKEEIEE_02258 1.6e-171 corA P Mg2 transporter protein CorA family protein
HNKEEIEE_02261 2.5e-235 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNKEEIEE_02262 9.6e-48 yhdT S Sodium pantothenate symporter
HNKEEIEE_02263 5.7e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HNKEEIEE_02264 6.4e-287 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HNKEEIEE_02265 1.1e-18 S Protein of unknown function (DUF4064)
HNKEEIEE_02266 1.5e-141 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HNKEEIEE_02267 9.3e-242 hom 1.1.1.3 E homoserine dehydrogenase
HNKEEIEE_02268 6.3e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HNKEEIEE_02269 5.3e-159 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HNKEEIEE_02270 8e-137 P ABC transporter, ATP-binding protein
HNKEEIEE_02271 9.8e-183 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HNKEEIEE_02272 2.1e-140 ssuC_1 P binding-protein-dependent transport systems inner membrane component
HNKEEIEE_02273 4.5e-120 M1-594 S Thiamine-binding protein
HNKEEIEE_02275 7.5e-100 nylA 3.5.1.4 J Belongs to the amidase family
HNKEEIEE_02276 6.1e-158 nylA 3.5.1.4 J Belongs to the amidase family
HNKEEIEE_02277 2.7e-85 S Heat induced stress protein YflT
HNKEEIEE_02278 6.6e-165 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HNKEEIEE_02279 8.2e-279 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HNKEEIEE_02280 7.8e-213 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HNKEEIEE_02281 1.2e-64 manO S Domain of unknown function (DUF956)
HNKEEIEE_02282 1.9e-169 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HNKEEIEE_02283 1.5e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HNKEEIEE_02284 1.1e-178 manL 2.7.1.191 G PTS system mannose fructose sorbose family
HNKEEIEE_02285 1.1e-84 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
HNKEEIEE_02286 0.0 levR K PTS system fructose IIA component
HNKEEIEE_02287 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HNKEEIEE_02288 1.5e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
HNKEEIEE_02289 2.9e-48 yqgV S Thiamine-binding protein
HNKEEIEE_02290 0.0 pip S YhgE Pip N-terminal domain protein
HNKEEIEE_02291 2.4e-98 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
HNKEEIEE_02292 4.8e-75 yabE S 3D domain
HNKEEIEE_02293 4.9e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HNKEEIEE_02295 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HNKEEIEE_02296 4.3e-20
HNKEEIEE_02297 7.1e-186 malR K Transcriptional regulator
HNKEEIEE_02298 2.8e-260 G Major facilitator Superfamily
HNKEEIEE_02299 0.0 mapA 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HNKEEIEE_02300 1.3e-125 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HNKEEIEE_02301 4.2e-68 L Integrase core domain
HNKEEIEE_02302 1.4e-74 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNKEEIEE_02303 1.2e-166 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HNKEEIEE_02304 4.9e-122 yhcW 5.4.2.6 S hydrolase
HNKEEIEE_02305 4.6e-158 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HNKEEIEE_02306 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNKEEIEE_02307 6.3e-108 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HNKEEIEE_02308 5.5e-30 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HNKEEIEE_02309 4.3e-116 IQ Short-chain dehydrogenase reductase sdr
HNKEEIEE_02310 5.4e-147 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HNKEEIEE_02311 2.5e-86
HNKEEIEE_02312 1.1e-73 3.4.21.121 O Belongs to the peptidase S8 family
HNKEEIEE_02313 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HNKEEIEE_02314 4.6e-160 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNKEEIEE_02315 1.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
HNKEEIEE_02316 7e-52 S Iron-sulphur cluster biosynthesis
HNKEEIEE_02317 1.8e-138 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HNKEEIEE_02318 1.4e-133 K helix_turn_helix, arabinose operon control protein
HNKEEIEE_02319 8.7e-229 G Bacterial extracellular solute-binding protein
HNKEEIEE_02320 1e-221 sugA G Binding-protein-dependent transport system inner membrane component
HNKEEIEE_02321 1.1e-147 G Binding-protein-dependent transport system inner membrane component
HNKEEIEE_02322 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
HNKEEIEE_02323 1.6e-216 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HNKEEIEE_02324 7e-228 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HNKEEIEE_02325 4.3e-175 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
HNKEEIEE_02326 2.3e-156 kdsA 2.5.1.55 M Belongs to the KdsA family
HNKEEIEE_02327 0.0 2.7.1.202 K transcriptional regulator, MtlR
HNKEEIEE_02328 9.8e-293 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNKEEIEE_02329 2.2e-249 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNKEEIEE_02330 2.5e-78
HNKEEIEE_02331 6.9e-53 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
HNKEEIEE_02332 3.1e-52 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HNKEEIEE_02333 6.6e-69 S Protein of unknown function (DUF2512)
HNKEEIEE_02334 0.0 O Belongs to the peptidase S8 family
HNKEEIEE_02335 2.6e-11 S Protein of unknown function (DUF1659)
HNKEEIEE_02336 9.8e-11 S Protein of unknown function (DUF2922)
HNKEEIEE_02337 2.2e-16 S YvrJ protein family
HNKEEIEE_02338 1.3e-205 EGP Major facilitator Superfamily
HNKEEIEE_02339 7.4e-169 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HNKEEIEE_02341 7e-62
HNKEEIEE_02342 2.7e-232 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HNKEEIEE_02343 1.8e-122 yvfI K COG2186 Transcriptional regulators
HNKEEIEE_02344 2.1e-299 yvfH C L-lactate permease
HNKEEIEE_02345 3e-12 S double-stranded DNA endodeoxyribonuclease activity
HNKEEIEE_02346 1.8e-150 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HNKEEIEE_02347 8.2e-82 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HNKEEIEE_02348 1.8e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HNKEEIEE_02349 9.7e-115 E LysE type translocator
HNKEEIEE_02350 4e-27
HNKEEIEE_02351 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
HNKEEIEE_02352 2.5e-97 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HNKEEIEE_02353 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HNKEEIEE_02354 3.9e-170 mrr V Mrr N-terminal domain
HNKEEIEE_02355 8.4e-53 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HNKEEIEE_02356 7e-198 L HKD family nuclease
HNKEEIEE_02357 1.9e-161 pstS P Phosphate
HNKEEIEE_02358 8.5e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HNKEEIEE_02359 2.8e-157 pstA P Phosphate transport system permease
HNKEEIEE_02360 9.5e-155 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNKEEIEE_02361 8.9e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNKEEIEE_02362 2.7e-174 M Glycosyltransferase like family 2
HNKEEIEE_02363 0.0
HNKEEIEE_02364 5e-57 P EamA-like transporter family
HNKEEIEE_02365 1.5e-50 S EamA-like transporter family
HNKEEIEE_02366 1.4e-118 yfbR S HD containing hydrolase-like enzyme
HNKEEIEE_02367 5.4e-34 csbA S protein conserved in bacteria
HNKEEIEE_02368 2.1e-09 S Uncharacterized conserved protein (DUF2164)
HNKEEIEE_02369 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HNKEEIEE_02370 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HNKEEIEE_02371 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HNKEEIEE_02372 6.1e-232 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNKEEIEE_02373 3.6e-232 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNKEEIEE_02374 4.5e-146 tagG GM Transport permease protein
HNKEEIEE_02375 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HNKEEIEE_02376 2.5e-174 yvlB S Putative adhesin
HNKEEIEE_02377 1.4e-32 yvlD S Membrane
HNKEEIEE_02378 3.3e-172 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HNKEEIEE_02379 9.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNKEEIEE_02380 1.7e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HNKEEIEE_02381 1.6e-72 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HNKEEIEE_02382 3.5e-256 S COG0457 FOG TPR repeat
HNKEEIEE_02383 3.1e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HNKEEIEE_02384 5.1e-86 yvcI 3.6.1.55 F Nudix hydrolase
HNKEEIEE_02385 1e-167 rapZ S Displays ATPase and GTPase activities
HNKEEIEE_02386 2.1e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HNKEEIEE_02387 4e-173 whiA K May be required for sporulation
HNKEEIEE_02388 4.3e-40 crh G Phosphocarrier protein Chr
HNKEEIEE_02389 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HNKEEIEE_02391 6.5e-19 S transposase or invertase
HNKEEIEE_02392 8.4e-265 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HNKEEIEE_02393 3.4e-29 sspB S spore protein
HNKEEIEE_02394 6.9e-206 msmK P Belongs to the ABC transporter superfamily
HNKEEIEE_02395 1e-170 lrp QT PucR C-terminal helix-turn-helix domain
HNKEEIEE_02396 3.3e-230 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
HNKEEIEE_02397 1.7e-270 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HNKEEIEE_02399 1e-212 yheC HJ YheC/D like ATP-grasp
HNKEEIEE_02400 4e-264 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HNKEEIEE_02401 5.3e-209 yheB S Belongs to the UPF0754 family
HNKEEIEE_02402 6.1e-55 yheA S Belongs to the UPF0342 family
HNKEEIEE_02403 2.7e-160 yhaX S hydrolases of the HAD superfamily
HNKEEIEE_02404 2.1e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
HNKEEIEE_02405 1.7e-27 S YhzD-like protein
HNKEEIEE_02406 9.6e-122 P Integral membrane protein TerC family
HNKEEIEE_02407 4.7e-149 ycgR S permeases
HNKEEIEE_02408 6.1e-69 ycgQ S membrane
HNKEEIEE_02409 1e-248 yhaO L DNA repair exonuclease
HNKEEIEE_02410 0.0 L AAA domain
HNKEEIEE_02411 1.1e-178 yhaM L Shows a 3'-5' exoribonuclease activity
HNKEEIEE_02412 3e-27 yhaL S Sporulation protein YhaL
HNKEEIEE_02413 2.3e-151 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HNKEEIEE_02416 3.7e-54 yhaI S Protein of unknown function (DUF1878)
HNKEEIEE_02417 4.4e-103 hpr K Negative regulator of protease production and sporulation
HNKEEIEE_02418 1.6e-18 yhaH S YtxH-like protein
HNKEEIEE_02419 6.5e-85 trpP S Tryptophan transporter TrpP
HNKEEIEE_02420 6.3e-75 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HNKEEIEE_02421 1.6e-137 ecsA V transporter (ATP-binding protein)
HNKEEIEE_02422 1.6e-219 ecsB U ABC transporter
HNKEEIEE_02423 6.3e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HNKEEIEE_02424 2.7e-239 yhfA C membrane
HNKEEIEE_02426 1.4e-95 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
HNKEEIEE_02427 5.5e-200 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HNKEEIEE_02428 4.2e-183 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HNKEEIEE_02429 2.1e-271 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HNKEEIEE_02430 8.3e-102 yhgD K Transcriptional regulator
HNKEEIEE_02431 1.5e-169 yhgE S YhgE Pip N-terminal domain protein
HNKEEIEE_02432 1.1e-69 EGP Major facilitator Superfamily
HNKEEIEE_02433 8.1e-166 EG EamA-like transporter family
HNKEEIEE_02434 2.8e-64 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HNKEEIEE_02435 6.7e-104 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HNKEEIEE_02436 1.9e-65 ytkA S YtkA-like
HNKEEIEE_02437 8e-22 yhfH S YhfH-like protein
HNKEEIEE_02438 8.5e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
HNKEEIEE_02439 2.4e-297 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
HNKEEIEE_02440 6.9e-122 azlC E AzlC protein
HNKEEIEE_02441 5.7e-41 azlD S branched-chain amino acid
HNKEEIEE_02442 4.5e-209 yhfN 3.4.24.84 O Peptidase M48
HNKEEIEE_02443 1.7e-08 S IDEAL
HNKEEIEE_02444 1.7e-96 comK K Competence transcription factor
HNKEEIEE_02445 6.4e-145 S Mitochondrial biogenesis AIM24
HNKEEIEE_02446 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HNKEEIEE_02447 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HNKEEIEE_02448 4.2e-30 gerPF S Spore germination protein gerPA/gerPF
HNKEEIEE_02449 9e-72 gerPE S Spore germination protein GerPE
HNKEEIEE_02450 2e-25 gerPD S Spore germination protein
HNKEEIEE_02451 8e-98 gerPC S Spore germination protein
HNKEEIEE_02452 8.7e-31 gerPA S Spore germination protein
HNKEEIEE_02453 9.6e-222 P Protein of unknown function (DUF418)
HNKEEIEE_02454 3.4e-163 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HNKEEIEE_02455 4.3e-59 yisL S UPF0344 protein
HNKEEIEE_02456 2.1e-105 yisN S Protein of unknown function (DUF2777)
HNKEEIEE_02457 3.8e-159 yitS S protein conserved in bacteria
HNKEEIEE_02458 2.2e-25 S Protein of unknown function (DUF3813)
HNKEEIEE_02459 1.3e-156 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HNKEEIEE_02460 9.5e-52 yitW S metal-sulfur cluster biosynthetic enzyme
HNKEEIEE_02461 5.2e-26 yjzC S YjzC-like protein
HNKEEIEE_02462 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HNKEEIEE_02463 2.4e-149 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
HNKEEIEE_02465 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNKEEIEE_02466 7.3e-236 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HNKEEIEE_02467 3.9e-150 yjaZ O Zn-dependent protease
HNKEEIEE_02468 1.3e-63 L Transposase IS4 family protein
HNKEEIEE_02469 5.3e-217 2.7.1.2 GK ROK family
HNKEEIEE_02470 2.2e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HNKEEIEE_02471 2.3e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNKEEIEE_02472 3.3e-180 3.1.1.5 I Alpha beta hydrolase
HNKEEIEE_02475 1.1e-236 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HNKEEIEE_02476 4.1e-131 ypmR1 E G-D-S-L family
HNKEEIEE_02477 1.3e-168 bcrA V ABC transporter, ATP-binding protein
HNKEEIEE_02478 1.3e-174 bcrB S ABC transporter (permease)
HNKEEIEE_02479 6.4e-88
HNKEEIEE_02480 5.1e-96 1.5.1.38 S FMN reductase
HNKEEIEE_02482 3e-144 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HNKEEIEE_02483 0.0 pflB 2.3.1.54 C formate acetyltransferase
HNKEEIEE_02485 7.6e-07 S Protein of unknown function (DUF2705)
HNKEEIEE_02486 1.2e-149 focA P Formate/nitrite transporter
HNKEEIEE_02487 2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HNKEEIEE_02488 1.4e-116 tcyB P COG0765 ABC-type amino acid transport system, permease component
HNKEEIEE_02489 5e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HNKEEIEE_02490 3.7e-84 S Rubrerythrin
HNKEEIEE_02491 1.6e-166 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HNKEEIEE_02492 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HNKEEIEE_02494 2.4e-275 cls2 I PLD-like domain
HNKEEIEE_02495 1.4e-68 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HNKEEIEE_02496 1.4e-215 rodA D Belongs to the SEDS family
HNKEEIEE_02497 7.1e-56 yusN M Coat F domain
HNKEEIEE_02498 2.4e-40
HNKEEIEE_02499 2.6e-14 S YuzL-like protein
HNKEEIEE_02500 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HNKEEIEE_02501 1e-215 fadA 2.3.1.16 I Belongs to the thiolase family
HNKEEIEE_02502 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HNKEEIEE_02503 1.3e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HNKEEIEE_02504 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HNKEEIEE_02505 8e-51 traF CO Thioredoxin
HNKEEIEE_02507 1.7e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HNKEEIEE_02508 6.7e-240 sufD O assembly protein SufD
HNKEEIEE_02509 9.1e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNKEEIEE_02510 6.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HNKEEIEE_02511 2.9e-273 sufB O FeS cluster assembly
HNKEEIEE_02512 1e-278 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HNKEEIEE_02513 6.9e-47 yunC S Domain of unknown function (DUF1805)
HNKEEIEE_02514 2.9e-128 yunB S Sporulation protein YunB (Spo_YunB)
HNKEEIEE_02515 2.8e-198 lytH M Peptidase, M23
HNKEEIEE_02516 1.1e-172 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HNKEEIEE_02517 3.4e-48 yutD S protein conserved in bacteria
HNKEEIEE_02518 1.9e-74 yutE S Protein of unknown function DUF86
HNKEEIEE_02519 1.8e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HNKEEIEE_02520 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HNKEEIEE_02521 1.4e-200 yutH S Spore coat protein
HNKEEIEE_02522 8.6e-37 nifU O COG0694 Thioredoxin-like proteins and domains
HNKEEIEE_02523 1.5e-58 yuzD S protein conserved in bacteria
HNKEEIEE_02524 2.2e-63 erpA S Belongs to the HesB IscA family
HNKEEIEE_02525 3.3e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
HNKEEIEE_02526 2.4e-231 yumB 1.6.99.3 C NADH dehydrogenase
HNKEEIEE_02527 2.1e-46 yuiB S Putative membrane protein
HNKEEIEE_02528 6.4e-108 yuiC S protein conserved in bacteria
HNKEEIEE_02529 2.1e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HNKEEIEE_02531 3.8e-296 gerKA EG Spore germination protein
HNKEEIEE_02532 7.9e-227 gerKC S spore germination
HNKEEIEE_02533 2.4e-193 E Spore germination protein
HNKEEIEE_02535 4.7e-58 yuzC
HNKEEIEE_02536 9.4e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HNKEEIEE_02537 3e-194 yuxJ EGP Major facilitator Superfamily
HNKEEIEE_02538 0.0 res 3.1.21.5 V Type III restriction enzyme, res subunit
HNKEEIEE_02539 9.6e-195 mod 2.1.1.72 L DNA methylase
HNKEEIEE_02540 8.6e-24 S Domain of unknown function (DUF4391)
HNKEEIEE_02541 3.3e-109 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNKEEIEE_02543 7.1e-239 S protein conserved in bacteria
HNKEEIEE_02544 2.4e-158 dkgB S Aldo/keto reductase family
HNKEEIEE_02545 1.2e-165 S reductase
HNKEEIEE_02546 9.5e-197 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HNKEEIEE_02547 5.9e-29 K Helix-turn-helix XRE-family like proteins
HNKEEIEE_02548 6.6e-152 msrR K COG1316 Transcriptional regulator
HNKEEIEE_02549 5.3e-99 yngC S membrane-associated protein
HNKEEIEE_02550 1.7e-232 S SNARE associated Golgi protein
HNKEEIEE_02551 2.4e-53 yodB K transcriptional
HNKEEIEE_02552 2.2e-196 S Protein of unknown function (DUF1648)
HNKEEIEE_02553 2.6e-70 K helix_turn_helix gluconate operon transcriptional repressor
HNKEEIEE_02554 2.5e-116 glnP P ABC transporter
HNKEEIEE_02555 6.1e-109 gluC P ABC transporter
HNKEEIEE_02556 1.2e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
HNKEEIEE_02557 7.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HNKEEIEE_02558 5e-174 ydbI S AI-2E family transporter
HNKEEIEE_02559 3.5e-222 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HNKEEIEE_02560 0.0 2.7.1.201, 2.7.1.211 G phosphotransferase system
HNKEEIEE_02561 1.5e-155 glcT K antiterminator
HNKEEIEE_02562 1.5e-234 pbuG S permease
HNKEEIEE_02564 2.9e-279 ywjA V ABC transporter
HNKEEIEE_02565 1e-19 ywjA V ABC transporter
HNKEEIEE_02566 9.4e-212 ynfM EGP Major facilitator Superfamily
HNKEEIEE_02568 5.4e-254 ybhI P Sodium:sulfate symporter transmembrane region
HNKEEIEE_02569 3.9e-88 endA 3.1.21.1 L Endonuclease I
HNKEEIEE_02570 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
HNKEEIEE_02571 2.2e-145
HNKEEIEE_02572 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNKEEIEE_02573 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNKEEIEE_02574 1.9e-71 yccU S CoA-binding protein
HNKEEIEE_02575 2.2e-97 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNKEEIEE_02576 1.4e-52 yneR S Belongs to the HesB IscA family
HNKEEIEE_02577 7.1e-52 yneQ
HNKEEIEE_02578 2.2e-75 yneP S thioesterase
HNKEEIEE_02579 4.1e-31 tlp S Belongs to the Tlp family
HNKEEIEE_02580 1.7e-19 sspN S Small acid-soluble spore protein N family
HNKEEIEE_02582 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HNKEEIEE_02583 2.2e-17 sspO S Belongs to the SspO family
HNKEEIEE_02584 7.1e-239 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HNKEEIEE_02585 2e-39
HNKEEIEE_02586 7.3e-18 sspP S Belongs to the SspP family
HNKEEIEE_02587 6.2e-09 S membrane
HNKEEIEE_02588 3.4e-109 M lytic transglycosylase activity
HNKEEIEE_02589 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HNKEEIEE_02590 4e-111 M effector of murein hydrolase
HNKEEIEE_02591 7.6e-62 S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HNKEEIEE_02592 3.2e-43 S Small, acid-soluble spore proteins, alpha/beta type
HNKEEIEE_02593 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HNKEEIEE_02594 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HNKEEIEE_02595 9.7e-52 iscA S Heme biosynthesis protein HemY
HNKEEIEE_02596 2e-234 ywoD EGP Major facilitator superfamily
HNKEEIEE_02598 1.1e-136
HNKEEIEE_02599 2.4e-198 yetN S Protein of unknown function (DUF3900)
HNKEEIEE_02600 5.2e-119 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HNKEEIEE_02601 2.4e-88 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HNKEEIEE_02602 1.4e-15
HNKEEIEE_02603 2.9e-47 yxaB GM Polysaccharide pyruvyl transferase
HNKEEIEE_02604 4.3e-42 S COG NOG14552 non supervised orthologous group
HNKEEIEE_02605 4.2e-47 L Resolvase, N terminal domain
HNKEEIEE_02606 2.3e-81 S Recombinase
HNKEEIEE_02607 9.6e-294 L Recombinase
HNKEEIEE_02608 1.1e-31
HNKEEIEE_02609 5e-133 3.5.1.28 M Sporulation related domain
HNKEEIEE_02610 1.3e-23 ymbI L Transposase
HNKEEIEE_02611 3.9e-96 S HTH-like domain
HNKEEIEE_02613 1.2e-252 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNKEEIEE_02614 8.5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HNKEEIEE_02615 7.3e-149 pdaA G deacetylase
HNKEEIEE_02616 3e-27 yfjT
HNKEEIEE_02617 3.7e-148 yfkD S YfkD-like protein
HNKEEIEE_02618 4e-174 cax P COG0387 Ca2 H antiporter
HNKEEIEE_02619 1.8e-220 yfkF EGP Major facilitator Superfamily
HNKEEIEE_02620 3.9e-148 yihY S Belongs to the UPF0761 family
HNKEEIEE_02621 2.8e-32 yfkK S Belongs to the UPF0435 family
HNKEEIEE_02622 3.6e-110 map 3.4.11.18 E Methionine aminopeptidase
HNKEEIEE_02623 1.6e-91 yfkM 3.5.1.124 S protease
HNKEEIEE_02624 1.9e-139 motB N Flagellar motor protein
HNKEEIEE_02625 6.6e-137 motA N flagellar motor
HNKEEIEE_02626 1.6e-58 yhdN S Domain of unknown function (DUF1992)
HNKEEIEE_02628 2.2e-60 yeaO S Protein of unknown function, DUF488
HNKEEIEE_02629 1e-229 EGP Major facilitator Superfamily
HNKEEIEE_02630 8.7e-147 dksA T COG1734 DnaK suppressor protein
HNKEEIEE_02631 1.3e-85 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HNKEEIEE_02632 3.8e-174 mreB D Rod-share determining protein MreBH
HNKEEIEE_02633 2.6e-171 yuaG S protein conserved in bacteria
HNKEEIEE_02634 3e-88 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HNKEEIEE_02635 1e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HNKEEIEE_02636 1.9e-169 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HNKEEIEE_02637 6.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HNKEEIEE_02638 5.4e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HNKEEIEE_02639 2.8e-102 4.2.1.1 P Reversible hydration of carbon dioxide
HNKEEIEE_02640 2.8e-298 3.1.21.5 V Type III restriction enzyme, res subunit
HNKEEIEE_02641 4.4e-231 2.1.1.72 L DNA methylase
HNKEEIEE_02642 0.0 3.6.4.12 L UvrD/REP helicase N-terminal domain
HNKEEIEE_02643 8.1e-216 EGP Major facilitator Superfamily
HNKEEIEE_02644 1.4e-153 2.7.1.202 K transcriptional regulator, MtlR
HNKEEIEE_02645 2.1e-213 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNKEEIEE_02646 2.7e-255 gph G MFS/sugar transport protein
HNKEEIEE_02647 2.4e-162 K helix_turn_helix, arabinose operon control protein
HNKEEIEE_02648 1.8e-11 ydjE EGP Major facilitator superfamily
HNKEEIEE_02649 1.7e-194 ydjE EGP Major facilitator superfamily
HNKEEIEE_02650 1.4e-74 K transcriptional
HNKEEIEE_02651 3.3e-201 EGP Major facilitator Superfamily
HNKEEIEE_02652 5.9e-180 K Transcriptional regulator
HNKEEIEE_02653 0.0 bga2 3.2.1.23 G beta-galactosidase
HNKEEIEE_02655 4e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HNKEEIEE_02656 3.5e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HNKEEIEE_02657 2.6e-115 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HNKEEIEE_02658 2.6e-211 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HNKEEIEE_02659 7.6e-38 NU cell adhesion
HNKEEIEE_02660 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
HNKEEIEE_02661 4.8e-221 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HNKEEIEE_02662 2.6e-89 K Belongs to the sigma-70 factor family. ECF subfamily
HNKEEIEE_02663 3.4e-83 S Putative zinc-finger
HNKEEIEE_02664 1.5e-123
HNKEEIEE_02665 8.9e-245 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
HNKEEIEE_02666 2.9e-139 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
HNKEEIEE_02667 1.3e-87 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HNKEEIEE_02668 1.6e-301 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HNKEEIEE_02669 7.5e-194 M1-600 T Putative diguanylate phosphodiesterase
HNKEEIEE_02670 8.5e-55 L resolvase
HNKEEIEE_02671 1.1e-36 S Domain of unknown function (DUF1413)
HNKEEIEE_02672 9.7e-31
HNKEEIEE_02673 2.6e-94
HNKEEIEE_02674 5.3e-103 T response regulator, receiver
HNKEEIEE_02675 2.3e-146 V ABC transporter
HNKEEIEE_02676 6.6e-102 S ABC-2 family transporter protein
HNKEEIEE_02677 1.1e-119 T PhoQ Sensor
HNKEEIEE_02678 1.3e-100 K DNA-binding transcription factor activity
HNKEEIEE_02679 3e-288 lmrA 3.6.3.44 V ABC transporter
HNKEEIEE_02680 3.3e-58 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HNKEEIEE_02681 1.6e-63 arsD S Arsenical resistance operon trans-acting repressor ArsD
HNKEEIEE_02682 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
HNKEEIEE_02683 1.2e-97 padR K Domain of unknown function (DUF2703)
HNKEEIEE_02684 8e-191 arsB P Arsenic resistance protein
HNKEEIEE_02685 2.4e-71 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
HNKEEIEE_02686 7.2e-172 ydhF S Oxidoreductase
HNKEEIEE_02687 9.5e-51
HNKEEIEE_02689 1.2e-174 K cell envelope-related transcriptional attenuator
HNKEEIEE_02690 0.0 ybeC E amino acid
HNKEEIEE_02691 4.7e-19 csd2 L CRISPR-associated protein Cas7
HNKEEIEE_02692 6.5e-187 csd1 S CRISPR-associated protein, Csd1 family
HNKEEIEE_02693 1.2e-188 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
HNKEEIEE_02694 4.2e-127 yeeN K transcriptional regulatory protein
HNKEEIEE_02695 5.8e-95
HNKEEIEE_02696 4e-116
HNKEEIEE_02697 5.8e-19
HNKEEIEE_02698 1.4e-195 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HNKEEIEE_02699 1.6e-151 fhuC 3.6.3.34 HP ABC transporter
HNKEEIEE_02700 2.1e-174 fhuD P Periplasmic binding protein
HNKEEIEE_02701 2.4e-179 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNKEEIEE_02702 1.1e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNKEEIEE_02703 4.1e-136 yfcA S membrane transporter protein
HNKEEIEE_02704 1.1e-53 ykkC P Multidrug resistance protein
HNKEEIEE_02705 2.2e-48 sugE P Multidrug resistance protein
HNKEEIEE_02706 1e-92 Q Thioesterase superfamily
HNKEEIEE_02707 1.3e-20 S transposase or invertase
HNKEEIEE_02708 3.3e-208 crtQ M Glycosyl transferase family 21
HNKEEIEE_02709 6.2e-103 plsY 2.3.1.15 I Belongs to the PlsY family
HNKEEIEE_02710 4.9e-193 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNKEEIEE_02711 5.6e-88 fld C Flavodoxin
HNKEEIEE_02712 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNKEEIEE_02715 1.3e-29 P Heavy-metal-associated domain
HNKEEIEE_02716 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HNKEEIEE_02717 1.5e-138 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HNKEEIEE_02718 1.5e-200 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HNKEEIEE_02719 1.7e-81 fld C Flavodoxin
HNKEEIEE_02720 4.9e-173 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HNKEEIEE_02721 1e-125 gntR K transcriptional
HNKEEIEE_02722 1.3e-306 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HNKEEIEE_02723 1.7e-230 EG COG2610 H gluconate symporter and related permeases
HNKEEIEE_02724 7.4e-132 treR K transcriptional
HNKEEIEE_02725 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HNKEEIEE_02726 5.9e-266 treP 2.7.1.201, 2.7.1.211 G phosphotransferase system
HNKEEIEE_02727 2.5e-83 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HNKEEIEE_02728 1.4e-268 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
HNKEEIEE_02729 6.7e-181 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HNKEEIEE_02730 5.1e-176 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNKEEIEE_02731 6.1e-33
HNKEEIEE_02732 2.2e-54 S DsrE/DsrF-like family
HNKEEIEE_02733 6.3e-213 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HNKEEIEE_02734 1.3e-221 mvaS 2.3.3.10 I synthase
HNKEEIEE_02735 6.2e-238 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
HNKEEIEE_02736 3.4e-135 spoIIR S Stage II sporulation protein R (spore_II_R)
HNKEEIEE_02737 1.1e-161 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HNKEEIEE_02738 1.7e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNKEEIEE_02740 1.3e-110 tdk 2.7.1.21 F thymidine kinase
HNKEEIEE_02741 2.2e-33 rpmE J Ribosomal protein L31
HNKEEIEE_02742 2.7e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HNKEEIEE_02743 2.7e-174 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HNKEEIEE_02744 8.1e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNKEEIEE_02745 2.6e-115 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HNKEEIEE_02746 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HNKEEIEE_02747 6e-61 spo0F T response regulator
HNKEEIEE_02748 4.7e-160
HNKEEIEE_02749 4.1e-142
HNKEEIEE_02750 6.5e-125 yhcG V ABC transporter, ATP-binding protein
HNKEEIEE_02751 6.8e-66 K helix_turn_helix gluconate operon transcriptional repressor
HNKEEIEE_02752 8.9e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HNKEEIEE_02753 3.5e-50 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HNKEEIEE_02755 0.0 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HNKEEIEE_02756 2.2e-41 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HNKEEIEE_02757 1.3e-111 kstR2_2 K Transcriptional regulator
HNKEEIEE_02758 3.2e-214 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HNKEEIEE_02759 1.4e-209 mmgC I acyl-CoA dehydrogenase
HNKEEIEE_02760 6.5e-218 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
HNKEEIEE_02761 0.0 fadF C COG0247 Fe-S oxidoreductase
HNKEEIEE_02762 1e-218 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HNKEEIEE_02763 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HNKEEIEE_02764 5e-75 ywiB S Domain of unknown function (DUF1934)
HNKEEIEE_02765 1.2e-168 speB 3.5.3.11 E Belongs to the arginase family
HNKEEIEE_02766 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNKEEIEE_02767 1.7e-93 ywhD S YwhD family
HNKEEIEE_02768 7.8e-120 ywhC S Peptidase M50
HNKEEIEE_02769 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HNKEEIEE_02770 1.5e-89 ywgA 2.1.1.72, 3.1.21.3
HNKEEIEE_02771 6.1e-257 ywfO S COG1078 HD superfamily phosphohydrolases
HNKEEIEE_02772 8.2e-99 rsfA S Transcriptional regulator
HNKEEIEE_02773 6.1e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HNKEEIEE_02774 3.6e-174 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HNKEEIEE_02775 9.5e-146 ywfI C May function as heme-dependent peroxidase
HNKEEIEE_02776 4.9e-81 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HNKEEIEE_02777 5.8e-56 ywdK S small membrane protein
HNKEEIEE_02778 2.7e-36 S Family of unknown function (DUF5327)
HNKEEIEE_02779 1.1e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HNKEEIEE_02780 5.7e-53 S Heat induced stress protein YflT
HNKEEIEE_02781 3.4e-135 IQ Enoyl-(Acyl carrier protein) reductase
HNKEEIEE_02782 2.7e-122 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HNKEEIEE_02783 7e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HNKEEIEE_02784 2e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HNKEEIEE_02785 2.5e-08 ykyB S YkyB-like protein
HNKEEIEE_02786 2.5e-126 yflK S protein conserved in bacteria
HNKEEIEE_02787 8.1e-276 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNKEEIEE_02788 1.1e-50 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNKEEIEE_02789 2.8e-89 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HNKEEIEE_02791 1.9e-20
HNKEEIEE_02792 1.2e-60 S AAA domain
HNKEEIEE_02795 9.3e-264 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HNKEEIEE_02796 1.4e-40 fdxA C 4Fe-4S binding domain
HNKEEIEE_02799 1.1e-134 S LXG domain of WXG superfamily
HNKEEIEE_02800 2.3e-61 S LXG domain of WXG superfamily
HNKEEIEE_02803 5.3e-192 adhP 1.1.1.1 C alcohol dehydrogenase
HNKEEIEE_02804 2.8e-29 S Nucleotidyltransferase domain
HNKEEIEE_02805 7.3e-211 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HNKEEIEE_02806 2.6e-117 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
HNKEEIEE_02807 1.9e-90 S Psort location CytoplasmicMembrane, score
HNKEEIEE_02808 1.2e-55 I Domain of unknown function (DUF4430)
HNKEEIEE_02809 6.5e-180 M FFAT motif binding
HNKEEIEE_02810 0.0 htpG O Molecular chaperone. Has ATPase activity
HNKEEIEE_02811 1.9e-209 hipO3 3.5.1.47 S amidohydrolase
HNKEEIEE_02812 7.9e-132 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HNKEEIEE_02813 5.8e-115 artQ E COG0765 ABC-type amino acid transport system, permease component
HNKEEIEE_02814 5e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HNKEEIEE_02815 2.3e-78 ymaD O redox protein, regulator of disulfide bond formation
HNKEEIEE_02816 1.7e-213 EGP Major facilitator Superfamily
HNKEEIEE_02817 1.9e-258 L PFAM Transposase, IS4-like
HNKEEIEE_02818 6.6e-131 yxaB GM Polysaccharide pyruvyl transferase
HNKEEIEE_02819 1.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNKEEIEE_02820 8.1e-185 bceS 2.7.13.3 T Signal transduction histidine kinase
HNKEEIEE_02821 4e-136 bceA V ABC transporter, ATP-binding protein
HNKEEIEE_02822 0.0 bceB V ABC transporter (permease)
HNKEEIEE_02823 8.1e-48 yxiS
HNKEEIEE_02824 5.3e-44 S Protein of unknown function (DUF1292)
HNKEEIEE_02825 6e-166 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
HNKEEIEE_02826 9.4e-118 folE 3.5.4.16 H GTP cyclohydrolase
HNKEEIEE_02827 2.7e-31 cspB K Cold shock
HNKEEIEE_02829 2.1e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNKEEIEE_02830 4.7e-24 S ATP synthase, subunit b
HNKEEIEE_02831 0.0 ubiB S ABC1 family
HNKEEIEE_02832 4.7e-189 yeaN P COG2807 Cyanate permease
HNKEEIEE_02833 3.6e-48 yxcD S Protein of unknown function (DUF2653)
HNKEEIEE_02834 1.1e-16
HNKEEIEE_02835 3e-136 ykrK S Domain of unknown function (DUF1836)
HNKEEIEE_02836 1.7e-122 P COG0569 K transport systems, NAD-binding component
HNKEEIEE_02837 1.7e-219 ktrB P COG0168 Trk-type K transport systems, membrane components
HNKEEIEE_02838 3.2e-175 rarD S -transporter
HNKEEIEE_02839 2.2e-54 L Recombinase
HNKEEIEE_02840 9.1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HNKEEIEE_02841 1.1e-85 mntP P Probably functions as a manganese efflux pump
HNKEEIEE_02842 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNKEEIEE_02843 2e-175 mcpA NT Chemotaxis
HNKEEIEE_02844 3.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HNKEEIEE_02845 4.4e-95 ywlG S Belongs to the UPF0340 family
HNKEEIEE_02846 5.4e-239 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HNKEEIEE_02847 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HNKEEIEE_02848 8e-53 atpI S ATP synthase I chain
HNKEEIEE_02849 5.8e-121 atpB C it plays a direct role in the translocation of protons across the membrane
HNKEEIEE_02850 2e-24 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNKEEIEE_02851 1.3e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HNKEEIEE_02852 1.3e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNKEEIEE_02853 5.9e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HNKEEIEE_02854 1.4e-148 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HNKEEIEE_02855 7.7e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HNKEEIEE_02856 2.1e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HNKEEIEE_02857 1.8e-34 ywzB S membrane
HNKEEIEE_02858 3.9e-136 ywmB S TATA-box binding
HNKEEIEE_02859 1.3e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNKEEIEE_02860 1.2e-08 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNKEEIEE_02861 2.8e-185 spoIID D Stage II sporulation protein D
HNKEEIEE_02862 1.8e-128 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HNKEEIEE_02863 6.5e-41 spoIIID K Stage III sporulation protein D
HNKEEIEE_02864 7.8e-180 mbl D Rod shape-determining protein
HNKEEIEE_02865 6.4e-145 flhO N flagellar basal body
HNKEEIEE_02866 3.7e-143 flhP N flagellar basal body
HNKEEIEE_02867 8.7e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HNKEEIEE_02869 3.3e-64 ssbB L Single-stranded DNA-binding protein
HNKEEIEE_02870 1.9e-71 ywpF S YwpF-like protein
HNKEEIEE_02873 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HNKEEIEE_02874 2e-307 ywqB S Zinc finger, swim domain protein
HNKEEIEE_02876 1.7e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HNKEEIEE_02877 2.3e-73 cueR K transcriptional
HNKEEIEE_02878 5e-235 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HNKEEIEE_02879 4.2e-149
HNKEEIEE_02880 1.5e-197 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HNKEEIEE_02881 7.3e-261 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HNKEEIEE_02882 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HNKEEIEE_02883 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HNKEEIEE_02884 1.9e-147 malA S Protein of unknown function (DUF1189)
HNKEEIEE_02885 6.7e-156 malD P transport
HNKEEIEE_02886 3.9e-240 malC P COG1175 ABC-type sugar transport systems, permease components
HNKEEIEE_02887 8.6e-224 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HNKEEIEE_02888 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HNKEEIEE_02889 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HNKEEIEE_02890 7.7e-177 yvdE K Transcriptional regulator
HNKEEIEE_02891 3.5e-123 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HNKEEIEE_02892 3.2e-107 E Lysine exporter protein LysE YggA
HNKEEIEE_02893 7e-259 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HNKEEIEE_02894 1.1e-101 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HNKEEIEE_02895 8.5e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HNKEEIEE_02896 3.2e-189 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HNKEEIEE_02897 1.1e-209 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNKEEIEE_02898 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HNKEEIEE_02899 7.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HNKEEIEE_02900 2.3e-105 narT P COG2223 Nitrate nitrite transporter
HNKEEIEE_02901 1.2e-163 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
HNKEEIEE_02902 3e-27
HNKEEIEE_02903 4.2e-52
HNKEEIEE_02905 2.8e-35 galM 5.1.3.3 G Aldose 1-epimerase
HNKEEIEE_02906 7.6e-97 galM 5.1.3.3 G Aldose 1-epimerase
HNKEEIEE_02907 9.7e-83 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HNKEEIEE_02908 1.8e-10 yxjG 2.1.1.14 E Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate
HNKEEIEE_02909 1.4e-133 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
HNKEEIEE_02910 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HNKEEIEE_02911 6e-35 yoeD G Helix-turn-helix domain
HNKEEIEE_02912 2.3e-119 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HNKEEIEE_02913 1.2e-210 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HNKEEIEE_02915 5.3e-89 1.8.5.2 S DoxX
HNKEEIEE_02916 4.7e-108 C Nitroreductase family
HNKEEIEE_02917 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HNKEEIEE_02918 5.8e-143 cas6 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
HNKEEIEE_02919 0.0
HNKEEIEE_02920 8.5e-184 cas7 L CRISPR-associated protein Cas7
HNKEEIEE_02921 2.8e-128 cas5 L TIGRFAM CRISPR-associated protein Cas5
HNKEEIEE_02922 0.0 L Metal dependent phosphohydrolases with conserved 'HD' motif.
HNKEEIEE_02923 5.7e-94 cas4 3.1.12.1 L TIGRFAM CRISPR-associated protein Cas4
HNKEEIEE_02924 1.1e-154 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HNKEEIEE_02925 5.8e-42 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HNKEEIEE_02926 0.0 S Protein of unknown function (DUF1524)
HNKEEIEE_02927 3.5e-249 S Protein of unknown function DUF262
HNKEEIEE_02928 6.3e-18
HNKEEIEE_02930 1.4e-98 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HNKEEIEE_02931 1e-123 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)