ORF_ID e_value Gene_name EC_number CAZy COGs Description
HILGINDI_00001 8.8e-184 yaaC S YaaC-like Protein
HILGINDI_00002 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HILGINDI_00003 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HILGINDI_00004 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HILGINDI_00005 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HILGINDI_00006 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HILGINDI_00007 4.9e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HILGINDI_00008 1.3e-09
HILGINDI_00009 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HILGINDI_00010 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HILGINDI_00011 1.7e-211 yaaH M Glycoside Hydrolase Family
HILGINDI_00012 2.6e-100 yaaI Q COG1335 Amidases related to nicotinamidase
HILGINDI_00013 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HILGINDI_00014 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HILGINDI_00015 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HILGINDI_00016 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HILGINDI_00017 3.6e-32 yaaL S Protein of unknown function (DUF2508)
HILGINDI_00018 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
HILGINDI_00019 2.2e-30 csfB S Inhibitor of sigma-G Gin
HILGINDI_00020 1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HILGINDI_00021 1.3e-188 yaaN P Belongs to the TelA family
HILGINDI_00022 3.1e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HILGINDI_00023 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HILGINDI_00024 7.5e-55 yaaQ S protein conserved in bacteria
HILGINDI_00025 1.2e-71 yaaR S protein conserved in bacteria
HILGINDI_00026 1.3e-182 holB 2.7.7.7 L DNA polymerase III
HILGINDI_00027 8.8e-145 yaaT S stage 0 sporulation protein
HILGINDI_00028 7.7e-37 yabA L Involved in initiation control of chromosome replication
HILGINDI_00029 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HILGINDI_00030 3.1e-47 yazA L endonuclease containing a URI domain
HILGINDI_00031 5.8e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HILGINDI_00032 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HILGINDI_00033 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HILGINDI_00034 6.9e-144 tatD L hydrolase, TatD
HILGINDI_00035 1.8e-232 rpfB GH23 T protein conserved in bacteria
HILGINDI_00036 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HILGINDI_00037 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HILGINDI_00038 8.4e-146 yabG S peptidase
HILGINDI_00039 7.8e-39 veg S protein conserved in bacteria
HILGINDI_00040 2.9e-27 sspF S DNA topological change
HILGINDI_00041 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HILGINDI_00042 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HILGINDI_00043 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HILGINDI_00044 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HILGINDI_00045 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HILGINDI_00046 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HILGINDI_00047 1e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HILGINDI_00048 6.1e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HILGINDI_00049 3.7e-40 yabK S Peptide ABC transporter permease
HILGINDI_00050 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HILGINDI_00051 6.2e-91 spoVT K stage V sporulation protein
HILGINDI_00052 4.1e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HILGINDI_00053 1.9e-275 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HILGINDI_00054 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HILGINDI_00055 1.9e-49 yabP S Sporulation protein YabP
HILGINDI_00056 1.7e-103 yabQ S spore cortex biosynthesis protein
HILGINDI_00057 4.1e-57 divIC D Septum formation initiator
HILGINDI_00058 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HILGINDI_00061 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HILGINDI_00062 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
HILGINDI_00063 2.1e-185 KLT serine threonine protein kinase
HILGINDI_00064 3.8e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HILGINDI_00065 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HILGINDI_00066 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HILGINDI_00067 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HILGINDI_00068 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HILGINDI_00069 2.8e-157 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HILGINDI_00070 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HILGINDI_00071 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HILGINDI_00072 1.8e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HILGINDI_00073 8.5e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HILGINDI_00074 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HILGINDI_00075 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HILGINDI_00076 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HILGINDI_00077 3.8e-28 yazB K transcriptional
HILGINDI_00078 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HILGINDI_00079 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HILGINDI_00080 7.5e-77 ctsR K Belongs to the CtsR family
HILGINDI_00081 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HILGINDI_00082 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HILGINDI_00083 0.0 clpC O Belongs to the ClpA ClpB family
HILGINDI_00084 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HILGINDI_00085 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HILGINDI_00086 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HILGINDI_00087 1.9e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HILGINDI_00088 2.6e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HILGINDI_00089 4e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HILGINDI_00090 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
HILGINDI_00091 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HILGINDI_00092 2.3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HILGINDI_00093 1.8e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HILGINDI_00094 4.2e-89 yacP S RNA-binding protein containing a PIN domain
HILGINDI_00095 8.9e-116 sigH K Belongs to the sigma-70 factor family
HILGINDI_00096 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HILGINDI_00097 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HILGINDI_00098 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HILGINDI_00099 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HILGINDI_00100 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HILGINDI_00101 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HILGINDI_00102 6.3e-108 rsmC 2.1.1.172 J Methyltransferase
HILGINDI_00103 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILGINDI_00104 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILGINDI_00105 2.1e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HILGINDI_00106 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HILGINDI_00107 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HILGINDI_00108 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HILGINDI_00109 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HILGINDI_00110 3.4e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HILGINDI_00111 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HILGINDI_00112 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HILGINDI_00113 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HILGINDI_00114 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HILGINDI_00115 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HILGINDI_00116 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HILGINDI_00117 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HILGINDI_00118 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HILGINDI_00119 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HILGINDI_00120 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HILGINDI_00121 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HILGINDI_00122 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HILGINDI_00123 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HILGINDI_00124 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HILGINDI_00125 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HILGINDI_00126 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HILGINDI_00127 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HILGINDI_00128 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HILGINDI_00129 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HILGINDI_00130 1.9e-23 rpmD J Ribosomal protein L30
HILGINDI_00131 1.1e-72 rplO J binds to the 23S rRNA
HILGINDI_00132 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HILGINDI_00133 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HILGINDI_00134 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
HILGINDI_00135 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HILGINDI_00136 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HILGINDI_00137 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HILGINDI_00138 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HILGINDI_00139 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILGINDI_00140 4.7e-58 rplQ J Ribosomal protein L17
HILGINDI_00141 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILGINDI_00142 3.6e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILGINDI_00143 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILGINDI_00144 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HILGINDI_00145 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HILGINDI_00146 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HILGINDI_00147 2.4e-144 ybaJ Q Methyltransferase domain
HILGINDI_00148 4.2e-83 yizA S Damage-inducible protein DinB
HILGINDI_00149 1.7e-78 ybaK S Protein of unknown function (DUF2521)
HILGINDI_00150 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HILGINDI_00151 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HILGINDI_00152 7.6e-76 gerD
HILGINDI_00153 1.7e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HILGINDI_00154 8.4e-134 pdaB 3.5.1.104 G Polysaccharide deacetylase
HILGINDI_00155 1.6e-219 glcP G Major Facilitator Superfamily
HILGINDI_00156 1.6e-246 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HILGINDI_00157 2e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HILGINDI_00158 2e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HILGINDI_00159 2.7e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HILGINDI_00160 7e-173 ybaS 1.1.1.58 S Na -dependent transporter
HILGINDI_00161 5.1e-115 ybbA S Putative esterase
HILGINDI_00162 1.8e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_00163 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_00164 2e-172 feuA P Iron-uptake system-binding protein
HILGINDI_00165 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HILGINDI_00166 1.2e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HILGINDI_00167 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HILGINDI_00168 3.1e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HILGINDI_00169 4.4e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILGINDI_00170 4.4e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HILGINDI_00171 9.1e-86 ybbJ J acetyltransferase
HILGINDI_00172 3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HILGINDI_00178 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HILGINDI_00179 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HILGINDI_00180 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HILGINDI_00181 1.6e-226 ybbR S protein conserved in bacteria
HILGINDI_00182 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HILGINDI_00183 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HILGINDI_00184 2.6e-155 V ATPases associated with a variety of cellular activities
HILGINDI_00185 5.4e-105 S ABC-2 family transporter protein
HILGINDI_00187 1.5e-18 6.3.2.14 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_00188 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_00189 8e-188 T PhoQ Sensor
HILGINDI_00190 7.4e-138 V ABC transporter, ATP-binding protein
HILGINDI_00191 0.0 V ABC transporter (permease)
HILGINDI_00192 8.9e-12 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HILGINDI_00193 1.2e-162 dkgB S Aldo/keto reductase family
HILGINDI_00194 1e-93 yxaC M effector of murein hydrolase
HILGINDI_00195 6.9e-52 S LrgA family
HILGINDI_00196 1.8e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
HILGINDI_00197 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HILGINDI_00198 2.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HILGINDI_00199 1.4e-201 T COG4585 Signal transduction histidine kinase
HILGINDI_00200 2.5e-110 KT LuxR family transcriptional regulator
HILGINDI_00201 1.1e-167 V COG1131 ABC-type multidrug transport system, ATPase component
HILGINDI_00202 1e-207 V COG0842 ABC-type multidrug transport system, permease component
HILGINDI_00203 1.9e-198 V ABC-2 family transporter protein
HILGINDI_00204 2.2e-24
HILGINDI_00205 4.5e-77 S Domain of unknown function (DUF4879)
HILGINDI_00206 4.9e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HILGINDI_00207 1e-109 yqeB
HILGINDI_00208 4.6e-39 ybyB
HILGINDI_00209 2.5e-292 ybeC E amino acid
HILGINDI_00210 1.5e-55
HILGINDI_00211 3.4e-15 S Protein of unknown function (DUF2651)
HILGINDI_00212 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HILGINDI_00213 2.3e-259 glpT G -transporter
HILGINDI_00214 1.3e-16 S Protein of unknown function (DUF2651)
HILGINDI_00215 1.9e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HILGINDI_00217 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HILGINDI_00218 3.5e-31
HILGINDI_00219 1.2e-82 K Helix-turn-helix XRE-family like proteins
HILGINDI_00220 4.3e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HILGINDI_00221 1.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HILGINDI_00222 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HILGINDI_00223 1.9e-86 ybfM S SNARE associated Golgi protein
HILGINDI_00224 2.5e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HILGINDI_00225 4.7e-42 ybfN
HILGINDI_00226 2.3e-192 yceA S Belongs to the UPF0176 family
HILGINDI_00227 4.2e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HILGINDI_00228 2.1e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HILGINDI_00229 1.4e-257 mmuP E amino acid
HILGINDI_00230 1.2e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HILGINDI_00231 2.7e-258 agcS E Sodium alanine symporter
HILGINDI_00232 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
HILGINDI_00233 5.9e-212 phoQ 2.7.13.3 T Histidine kinase
HILGINDI_00234 5.7e-172 glnL T Regulator
HILGINDI_00235 1.2e-36 ycbJ S Macrolide 2'-phosphotransferase
HILGINDI_00236 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HILGINDI_00237 2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HILGINDI_00238 1.5e-112 ydfN C nitroreductase
HILGINDI_00239 3.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HILGINDI_00240 1.5e-62 mhqP S DoxX
HILGINDI_00241 3.7e-57 traF CO Thioredoxin
HILGINDI_00242 5.6e-62 ycbP S Protein of unknown function (DUF2512)
HILGINDI_00243 5.3e-77 sleB 3.5.1.28 M Cell wall
HILGINDI_00244 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HILGINDI_00245 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HILGINDI_00246 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HILGINDI_00247 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HILGINDI_00248 7.6e-208 ycbU E Selenocysteine lyase
HILGINDI_00249 1.1e-230 lmrB EGP the major facilitator superfamily
HILGINDI_00250 2.7e-100 yxaF K Transcriptional regulator
HILGINDI_00251 4.4e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HILGINDI_00252 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HILGINDI_00253 1.4e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
HILGINDI_00254 4.3e-172 yccK C Aldo keto reductase
HILGINDI_00255 6.2e-177 ycdA S Domain of unknown function (DUF5105)
HILGINDI_00256 1e-262 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HILGINDI_00257 3.9e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HILGINDI_00258 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
HILGINDI_00259 9.3e-190 S response regulator aspartate phosphatase
HILGINDI_00260 7.3e-141 IQ Enoyl-(Acyl carrier protein) reductase
HILGINDI_00261 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HILGINDI_00262 3.9e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
HILGINDI_00263 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HILGINDI_00264 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HILGINDI_00265 1.2e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILGINDI_00266 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HILGINDI_00267 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
HILGINDI_00268 1.3e-107 yceE T proteins involved in stress response, homologs of TerZ and
HILGINDI_00269 9.7e-138 terC P Protein of unknown function (DUF475)
HILGINDI_00270 0.0 yceG S Putative component of 'biosynthetic module'
HILGINDI_00271 2.3e-193 yceH P Belongs to the TelA family
HILGINDI_00272 2.1e-216 naiP P Uncharacterised MFS-type transporter YbfB
HILGINDI_00273 3.9e-229 proV 3.6.3.32 E glycine betaine
HILGINDI_00274 1.6e-138 opuAB P glycine betaine
HILGINDI_00275 3.1e-164 opuAC E glycine betaine
HILGINDI_00276 2.3e-212 amhX S amidohydrolase
HILGINDI_00277 1.1e-230 ycgA S Membrane
HILGINDI_00278 6.3e-82 ycgB
HILGINDI_00279 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HILGINDI_00280 4.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HILGINDI_00283 2.3e-42
HILGINDI_00286 6.5e-62 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
HILGINDI_00288 5.3e-28 cobT 1.13.11.79, 2.4.2.21 C coenzyme F420-1:gamma-L-glutamate ligase activity
HILGINDI_00289 1.9e-16 C Nitroreductase
HILGINDI_00291 5.2e-48 V COG1131 ABC-type multidrug transport system, ATPase component
HILGINDI_00292 1.8e-19 V ABC-2 type transporter
HILGINDI_00293 6.2e-261 mdr EGP Major facilitator Superfamily
HILGINDI_00294 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HILGINDI_00295 4.7e-114 ycgF E Lysine exporter protein LysE YggA
HILGINDI_00296 1.7e-150 yqcI S YqcI/YcgG family
HILGINDI_00297 3.7e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HILGINDI_00298 7.6e-114 ycgI S Domain of unknown function (DUF1989)
HILGINDI_00299 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HILGINDI_00301 4.5e-138 4.2.1.118 G Xylose isomerase-like TIM barrel
HILGINDI_00302 2.7e-233 G COG0477 Permeases of the major facilitator superfamily
HILGINDI_00303 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HILGINDI_00304 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HILGINDI_00305 8.1e-148 ycgL S Predicted nucleotidyltransferase
HILGINDI_00306 2.3e-170 ycgM E Proline dehydrogenase
HILGINDI_00307 3.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HILGINDI_00308 6.4e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HILGINDI_00309 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HILGINDI_00310 3.2e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HILGINDI_00311 7.3e-280 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HILGINDI_00312 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
HILGINDI_00313 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HILGINDI_00314 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HILGINDI_00315 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HILGINDI_00316 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
HILGINDI_00317 4.9e-229 yciC S GTPases (G3E family)
HILGINDI_00318 2.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HILGINDI_00319 2.8e-73 yckC S membrane
HILGINDI_00320 8.4e-51 S Protein of unknown function (DUF2680)
HILGINDI_00321 1.6e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HILGINDI_00322 1e-66 nin S Competence protein J (ComJ)
HILGINDI_00323 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
HILGINDI_00324 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HILGINDI_00325 1.1e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HILGINDI_00326 6.3e-63 hxlR K transcriptional
HILGINDI_00327 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_00328 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_00329 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HILGINDI_00330 1.5e-140 srfAD Q thioesterase
HILGINDI_00331 1.6e-249 bamJ E Aminotransferase class I and II
HILGINDI_00332 1.6e-131 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HILGINDI_00333 6.3e-111 yczE S membrane
HILGINDI_00334 1.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HILGINDI_00335 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
HILGINDI_00336 4.7e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HILGINDI_00337 2.8e-157 bsdA K LysR substrate binding domain
HILGINDI_00338 2.1e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HILGINDI_00339 2.4e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HILGINDI_00340 2e-38 bsdD 4.1.1.61 S response to toxic substance
HILGINDI_00341 1.2e-77 yclD
HILGINDI_00342 4.1e-270 dtpT E amino acid peptide transporter
HILGINDI_00343 1.5e-282 yclG M Pectate lyase superfamily protein
HILGINDI_00345 9.2e-295 gerKA EG Spore germination protein
HILGINDI_00346 3.2e-236 gerKC S spore germination
HILGINDI_00347 1.9e-195 gerKB F Spore germination protein
HILGINDI_00348 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILGINDI_00349 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILGINDI_00350 2.7e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
HILGINDI_00351 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
HILGINDI_00352 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HILGINDI_00353 9.8e-219 yxeP 3.5.1.47 E hydrolase activity
HILGINDI_00354 2.9e-254 yxeQ S MmgE/PrpD family
HILGINDI_00355 3.3e-121 yclH P ABC transporter
HILGINDI_00356 1.4e-235 yclI V ABC transporter (permease) YclI
HILGINDI_00357 4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_00358 3.4e-261 T PhoQ Sensor
HILGINDI_00359 4e-79 S aspartate phosphatase
HILGINDI_00361 3.2e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HILGINDI_00362 3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_00363 1e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_00364 6.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HILGINDI_00365 3.2e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HILGINDI_00366 1.7e-249 ycnB EGP Major facilitator Superfamily
HILGINDI_00367 1.2e-152 ycnC K Transcriptional regulator
HILGINDI_00368 2.3e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
HILGINDI_00369 1e-44 ycnE S Monooxygenase
HILGINDI_00370 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HILGINDI_00371 1.2e-263 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILGINDI_00372 1.6e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HILGINDI_00373 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HILGINDI_00374 6.1e-149 glcU U Glucose uptake
HILGINDI_00375 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_00376 1.3e-97 ycnI S protein conserved in bacteria
HILGINDI_00377 9.4e-300 ycnJ P protein, homolog of Cu resistance protein CopC
HILGINDI_00378 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HILGINDI_00379 6e-55
HILGINDI_00380 1.6e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HILGINDI_00381 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HILGINDI_00382 5.4e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HILGINDI_00383 1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HILGINDI_00385 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HILGINDI_00386 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
HILGINDI_00387 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HILGINDI_00388 2.7e-151 ycsI S Belongs to the D-glutamate cyclase family
HILGINDI_00389 6e-137 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HILGINDI_00390 7.1e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HILGINDI_00391 1.2e-130 kipR K Transcriptional regulator
HILGINDI_00392 2.7e-117 ycsK E anatomical structure formation involved in morphogenesis
HILGINDI_00394 5.1e-56 yczJ S biosynthesis
HILGINDI_00395 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HILGINDI_00396 2.6e-174 ydhF S Oxidoreductase
HILGINDI_00397 0.0 mtlR K transcriptional regulator, MtlR
HILGINDI_00398 5.9e-288 ydaB IQ acyl-CoA ligase
HILGINDI_00399 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_00400 2.3e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HILGINDI_00401 1.9e-96 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HILGINDI_00402 1.4e-77 ydaG 1.4.3.5 S general stress protein
HILGINDI_00403 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HILGINDI_00404 1.3e-47 ydzA EGP Major facilitator Superfamily
HILGINDI_00405 4.3e-74 lrpC K Transcriptional regulator
HILGINDI_00406 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HILGINDI_00407 4.2e-203 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HILGINDI_00408 1.8e-148 ydaK T Diguanylate cyclase, GGDEF domain
HILGINDI_00409 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HILGINDI_00410 7.2e-231 ydaM M Glycosyl transferase family group 2
HILGINDI_00411 0.0 ydaN S Bacterial cellulose synthase subunit
HILGINDI_00412 0.0 ydaO E amino acid
HILGINDI_00413 1.2e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HILGINDI_00414 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HILGINDI_00415 4.7e-11
HILGINDI_00417 3.9e-72
HILGINDI_00418 3.5e-100
HILGINDI_00419 2.1e-39
HILGINDI_00420 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
HILGINDI_00422 6.5e-34 ydaT
HILGINDI_00423 1.1e-71 yvaD S Family of unknown function (DUF5360)
HILGINDI_00424 2.1e-53 yvaE P Small Multidrug Resistance protein
HILGINDI_00425 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HILGINDI_00427 9.6e-64 ydbB G Cupin domain
HILGINDI_00428 6.3e-63 ydbC S Domain of unknown function (DUF4937
HILGINDI_00429 2.5e-155 ydbD P Catalase
HILGINDI_00430 2.2e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HILGINDI_00431 1.2e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HILGINDI_00432 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HILGINDI_00433 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HILGINDI_00434 3.2e-160 ydbI S AI-2E family transporter
HILGINDI_00435 5e-173 ydbJ V ABC transporter, ATP-binding protein
HILGINDI_00436 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HILGINDI_00437 6.1e-52 ydbL
HILGINDI_00438 2.4e-206 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HILGINDI_00439 1.5e-10 S Fur-regulated basic protein B
HILGINDI_00440 5.8e-09 S Fur-regulated basic protein A
HILGINDI_00441 2.4e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HILGINDI_00442 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HILGINDI_00443 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HILGINDI_00444 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HILGINDI_00445 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HILGINDI_00446 1.3e-60 ydbS S Bacterial PH domain
HILGINDI_00447 8.2e-263 ydbT S Membrane
HILGINDI_00448 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HILGINDI_00449 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HILGINDI_00450 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HILGINDI_00451 4e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HILGINDI_00452 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HILGINDI_00453 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HILGINDI_00454 1.5e-144 rsbR T Positive regulator of sigma-B
HILGINDI_00455 1.8e-57 rsbS T antagonist
HILGINDI_00456 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HILGINDI_00457 4.6e-188 rsbU 3.1.3.3 KT phosphatase
HILGINDI_00458 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HILGINDI_00459 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HILGINDI_00460 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILGINDI_00461 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HILGINDI_00462 0.0 yhgF K COG2183 Transcriptional accessory protein
HILGINDI_00463 1.7e-14
HILGINDI_00464 1.9e-58 ydcK S Belongs to the SprT family
HILGINDI_00473 2.1e-43
HILGINDI_00474 3.7e-19 S LXG domain of WXG superfamily
HILGINDI_00475 2.1e-44 yobL L nucleic acid phosphodiester bond hydrolysis
HILGINDI_00476 6.1e-31 M nucleic acid phosphodiester bond hydrolysis
HILGINDI_00477 1.9e-113 M1-798 KP helix_turn_helix, Arsenical Resistance Operon Repressor
HILGINDI_00478 1.3e-43 P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HILGINDI_00479 2.6e-204 ydeG EGP Major facilitator superfamily
HILGINDI_00480 3.4e-24 yyaL O Highly conserved protein containing a thioredoxin domain
HILGINDI_00481 4.8e-71 K Transcriptional regulator
HILGINDI_00482 1.2e-64 E LysE type translocator
HILGINDI_00483 1.6e-57 alaS2 6.1.1.7 S Threonyl and Alanyl tRNA synthetase second additional domain
HILGINDI_00484 3.1e-95 ywrO S Flavodoxin-like fold
HILGINDI_00485 5.5e-232 proP EGP Transporter
HILGINDI_00486 2.9e-48 ohrR K Transcriptional regulator
HILGINDI_00487 3.8e-48 S Domain of unknown function with cystatin-like fold (DUF4467)
HILGINDI_00488 3e-72 maoC I N-terminal half of MaoC dehydratase
HILGINDI_00489 3.2e-64 yyaQ S YjbR
HILGINDI_00490 1.7e-70 ywnA K Transcriptional regulator
HILGINDI_00491 3.8e-111 ywnB S NAD(P)H-binding
HILGINDI_00493 5.5e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HILGINDI_00494 1.4e-30 cspL K Cold shock
HILGINDI_00495 1e-78 carD K Transcription factor
HILGINDI_00496 3.9e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HILGINDI_00497 8e-89 S Protein of unknown function (DUF2812)
HILGINDI_00498 2.2e-51 K Transcriptional regulator PadR-like family
HILGINDI_00499 2.7e-152 K Transcriptional regulator
HILGINDI_00500 6e-255 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HILGINDI_00501 1.1e-181 S Patatin-like phospholipase
HILGINDI_00502 3.8e-84 S DinB superfamily
HILGINDI_00503 2.2e-63 G Cupin domain
HILGINDI_00505 6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
HILGINDI_00506 3.4e-79 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILGINDI_00507 1.7e-168 czcD P COG1230 Co Zn Cd efflux system component
HILGINDI_00508 1.6e-199 trkA P Oxidoreductase
HILGINDI_00510 1.5e-100 yrkC G Cupin domain
HILGINDI_00511 8.9e-29 ykkA S Protein of unknown function (DUF664)
HILGINDI_00512 3.5e-45 ykkA S Protein of unknown function (DUF664)
HILGINDI_00513 2.3e-150 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
HILGINDI_00515 6e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HILGINDI_00516 1.6e-56 ydeH
HILGINDI_00517 3.7e-84 F nucleoside 2-deoxyribosyltransferase
HILGINDI_00518 4.8e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HILGINDI_00519 1.2e-148 Q ubiE/COQ5 methyltransferase family
HILGINDI_00520 5.8e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HILGINDI_00521 5.2e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HILGINDI_00522 7.8e-169 S Sodium Bile acid symporter family
HILGINDI_00523 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
HILGINDI_00524 8e-67 yraB K helix_turn_helix, mercury resistance
HILGINDI_00525 2.1e-222 mleN_2 C antiporter
HILGINDI_00526 9.2e-264 K helix_turn_helix gluconate operon transcriptional repressor
HILGINDI_00527 1.9e-112 paiB K Transcriptional regulator
HILGINDI_00529 3.7e-108 ksgA1 I Ribosomal RNA adenine dimethylase
HILGINDI_00530 5.4e-124 T Transcriptional regulator
HILGINDI_00531 9.9e-189 T PhoQ Sensor
HILGINDI_00532 2e-104 S SNARE associated Golgi protein
HILGINDI_00533 4.2e-180 ydeR EGP Major facilitator Superfamily
HILGINDI_00534 1.3e-102 ydeS K Transcriptional regulator
HILGINDI_00535 7.4e-158 ydeK EG -transporter
HILGINDI_00536 3.2e-264 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILGINDI_00537 6.2e-48 yraD M Spore coat protein
HILGINDI_00538 4.9e-25 yraE
HILGINDI_00539 4.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HILGINDI_00540 8.4e-63 yraF M Spore coat protein
HILGINDI_00541 2.6e-36 yraG
HILGINDI_00542 2.3e-109 ybjJ G Major Facilitator Superfamily
HILGINDI_00543 1.7e-76 2.7.1.2 GK Transcriptional regulator
HILGINDI_00544 2.4e-71 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HILGINDI_00545 4.4e-220 ydfH 2.7.13.3 T Histidine kinase
HILGINDI_00546 3.7e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILGINDI_00547 0.0 ydfJ S drug exporters of the RND superfamily
HILGINDI_00548 3e-133 puuD S Peptidase C26
HILGINDI_00549 1.9e-219 mmr U Major Facilitator Superfamily
HILGINDI_00550 8.7e-73 yffB K Transcriptional regulator
HILGINDI_00551 3.6e-299 expZ S ABC transporter
HILGINDI_00552 7.9e-99 ynaD J Acetyltransferase (GNAT) domain
HILGINDI_00553 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
HILGINDI_00554 3.9e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HILGINDI_00555 5.1e-210 tcaB EGP Major facilitator Superfamily
HILGINDI_00556 6.8e-226 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HILGINDI_00557 1.5e-155 K Helix-turn-helix XRE-family like proteins
HILGINDI_00558 1.3e-123 ydhB S membrane transporter protein
HILGINDI_00559 6.5e-81 bltD 2.3.1.57 K FR47-like protein
HILGINDI_00560 4.1e-150 bltR K helix_turn_helix, mercury resistance
HILGINDI_00561 3.6e-149 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HILGINDI_00562 5.1e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HILGINDI_00563 2.2e-145 ycgJ_1 Q ubiE/COQ5 methyltransferase family
HILGINDI_00564 2.3e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HILGINDI_00565 6.9e-119 ydhC K FCD
HILGINDI_00566 4.9e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HILGINDI_00569 2e-263 pbpE V Beta-lactamase
HILGINDI_00571 7.2e-98 ydhK M Protein of unknown function (DUF1541)
HILGINDI_00572 5.8e-195 pbuE EGP Major facilitator Superfamily
HILGINDI_00573 1.3e-133 ydhQ K UTRA
HILGINDI_00574 5.3e-119 K FCD
HILGINDI_00575 7.4e-217 yeaN P COG2807 Cyanate permease
HILGINDI_00576 2.6e-49 sugE P Small Multidrug Resistance protein
HILGINDI_00577 2.3e-51 ykkC P Small Multidrug Resistance protein
HILGINDI_00578 5.3e-104 yvdT K Transcriptional regulator
HILGINDI_00579 1.2e-296 yveA E amino acid
HILGINDI_00580 3.2e-166 ydhU P Catalase
HILGINDI_00581 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HILGINDI_00582 1.4e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
HILGINDI_00583 7e-251 iolT EGP Major facilitator Superfamily
HILGINDI_00586 7.8e-08
HILGINDI_00588 8.7e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HILGINDI_00589 7e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HILGINDI_00590 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HILGINDI_00591 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HILGINDI_00592 2.3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HILGINDI_00593 0.0 ydiF S ABC transporter
HILGINDI_00594 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HILGINDI_00595 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HILGINDI_00596 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HILGINDI_00597 2.7e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HILGINDI_00598 1.7e-27 ydiK S Domain of unknown function (DUF4305)
HILGINDI_00599 2.5e-127 ydiL S CAAX protease self-immunity
HILGINDI_00600 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HILGINDI_00601 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HILGINDI_00602 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
HILGINDI_00605 9.5e-65
HILGINDI_00606 0.0 K NB-ARC domain
HILGINDI_00607 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
HILGINDI_00608 1.1e-248 gutA G MFS/sugar transport protein
HILGINDI_00609 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HILGINDI_00610 2.3e-29 yjdJ S Domain of unknown function (DUF4306)
HILGINDI_00611 4.3e-113 pspA KT Phage shock protein A
HILGINDI_00612 1.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HILGINDI_00613 3.7e-121 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HILGINDI_00614 1.1e-154 ydjI S virion core protein (lumpy skin disease virus)
HILGINDI_00615 0.0 yrhL I Acyltransferase family
HILGINDI_00616 1.2e-147 rsiV S Protein of unknown function (DUF3298)
HILGINDI_00617 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HILGINDI_00618 1.8e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HILGINDI_00619 4.2e-62 ydjM M Lytic transglycolase
HILGINDI_00620 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
HILGINDI_00622 7.2e-35 ydjO S Cold-inducible protein YdjO
HILGINDI_00623 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HILGINDI_00624 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HILGINDI_00625 7.1e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HILGINDI_00626 4.6e-177 yeaC S COG0714 MoxR-like ATPases
HILGINDI_00627 1.4e-215 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HILGINDI_00628 0.0 yebA E COG1305 Transglutaminase-like enzymes
HILGINDI_00629 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HILGINDI_00630 3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HILGINDI_00631 9.3e-259 S Domain of unknown function (DUF4179)
HILGINDI_00632 6.2e-209 pbuG S permease
HILGINDI_00633 1.9e-125 yebC M Membrane
HILGINDI_00635 2e-92 yebE S UPF0316 protein
HILGINDI_00636 5.5e-29 yebG S NETI protein
HILGINDI_00637 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HILGINDI_00638 1.4e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HILGINDI_00639 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HILGINDI_00640 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HILGINDI_00641 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILGINDI_00642 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILGINDI_00643 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILGINDI_00644 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HILGINDI_00645 4.6e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HILGINDI_00646 7e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HILGINDI_00647 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HILGINDI_00648 1.8e-234 purD 6.3.4.13 F Belongs to the GARS family
HILGINDI_00649 2e-25 S Protein of unknown function (DUF2892)
HILGINDI_00650 0.0 yerA 3.5.4.2 F adenine deaminase
HILGINDI_00651 1.4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
HILGINDI_00652 2.4e-50 yerC S protein conserved in bacteria
HILGINDI_00653 6.7e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HILGINDI_00654 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HILGINDI_00655 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HILGINDI_00656 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HILGINDI_00657 2.3e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
HILGINDI_00658 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
HILGINDI_00659 4.3e-121 sapB S MgtC SapB transporter
HILGINDI_00660 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HILGINDI_00661 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HILGINDI_00662 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HILGINDI_00663 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HILGINDI_00664 9.6e-155 yerO K Transcriptional regulator
HILGINDI_00665 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HILGINDI_00666 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HILGINDI_00667 7.6e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HILGINDI_00668 7.5e-85
HILGINDI_00669 6.3e-103 H Prokaryotic E2 family B
HILGINDI_00670 2.7e-27 S Prokaryotic homologs of the JAB domain
HILGINDI_00671 4.4e-78 V HNH nucleases
HILGINDI_00672 1.9e-159 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HILGINDI_00673 9.3e-137 cylB V ABC-2 type transporter
HILGINDI_00674 1.1e-62 S Protein of unknown function, DUF600
HILGINDI_00675 1.2e-50 S Protein of unknown function, DUF600
HILGINDI_00676 4.5e-53 S Protein of unknown function, DUF600
HILGINDI_00677 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
HILGINDI_00678 1.3e-16
HILGINDI_00679 9.4e-127 yeeN K transcriptional regulatory protein
HILGINDI_00681 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
HILGINDI_00682 3.3e-45 cotJB S CotJB protein
HILGINDI_00683 8.9e-104 cotJC P Spore Coat
HILGINDI_00684 6.4e-96 yesJ K Acetyltransferase (GNAT) family
HILGINDI_00686 1.8e-119 yetF S membrane
HILGINDI_00687 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HILGINDI_00688 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILGINDI_00689 2.6e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HILGINDI_00690 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
HILGINDI_00691 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
HILGINDI_00692 1.1e-105 yetJ S Belongs to the BI1 family
HILGINDI_00693 2.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HILGINDI_00694 3.5e-205 yetM CH FAD binding domain
HILGINDI_00695 7.5e-197 yetN S Protein of unknown function (DUF3900)
HILGINDI_00696 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HILGINDI_00698 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HILGINDI_00699 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HILGINDI_00700 2.4e-172 yfnG 4.2.1.45 M dehydratase
HILGINDI_00701 2.3e-178 yfnF M Nucleotide-diphospho-sugar transferase
HILGINDI_00702 8.6e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HILGINDI_00703 4e-186 yfnD M Nucleotide-diphospho-sugar transferase
HILGINDI_00704 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
HILGINDI_00705 6.6e-246 yfnA E amino acid
HILGINDI_00706 7.7e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HILGINDI_00707 9.8e-115 yfmS NT chemotaxis protein
HILGINDI_00708 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
HILGINDI_00709 1.6e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HILGINDI_00710 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HILGINDI_00711 3.1e-69 yfmP K transcriptional
HILGINDI_00712 2.1e-208 yfmO EGP Major facilitator Superfamily
HILGINDI_00713 4.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HILGINDI_00714 4.2e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HILGINDI_00715 3.9e-18 yfmK 2.3.1.128 K acetyltransferase
HILGINDI_00716 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
HILGINDI_00717 1.2e-24 S Protein of unknown function (DUF3212)
HILGINDI_00718 1.3e-57 yflT S Heat induced stress protein YflT
HILGINDI_00719 6.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HILGINDI_00720 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
HILGINDI_00721 1.5e-26 Q PFAM Collagen triple helix
HILGINDI_00723 2.7e-14 Q calcium- and calmodulin-responsive adenylate cyclase activity
HILGINDI_00726 3.3e-23 M1-820 Q Collagen triple helix repeat (20 copies)
HILGINDI_00727 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
HILGINDI_00728 2.1e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HILGINDI_00729 1.2e-118 citT T response regulator
HILGINDI_00730 3.5e-177 yflP S Tripartite tricarboxylate transporter family receptor
HILGINDI_00731 7.2e-226 citM C Citrate transporter
HILGINDI_00732 2.5e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HILGINDI_00733 1.1e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HILGINDI_00734 2.2e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HILGINDI_00735 4.4e-123 yflK S protein conserved in bacteria
HILGINDI_00736 1.5e-14 yflJ S Protein of unknown function (DUF2639)
HILGINDI_00737 7e-19 yflI
HILGINDI_00738 2e-49 yflH S Protein of unknown function (DUF3243)
HILGINDI_00739 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
HILGINDI_00740 8.7e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HILGINDI_00741 6.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HILGINDI_00742 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HILGINDI_00743 7.8e-64 yhdN S Domain of unknown function (DUF1992)
HILGINDI_00744 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
HILGINDI_00745 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
HILGINDI_00746 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
HILGINDI_00747 1.6e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILGINDI_00748 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HILGINDI_00749 9e-130 treR K transcriptional
HILGINDI_00750 1.2e-123 yfkO C nitroreductase
HILGINDI_00751 4.2e-125 yibF S YibE/F-like protein
HILGINDI_00752 4.1e-201 yibE S YibE/F-like protein
HILGINDI_00754 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HILGINDI_00755 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HILGINDI_00756 1.5e-186 K helix_turn _helix lactose operon repressor
HILGINDI_00757 9.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HILGINDI_00758 1.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HILGINDI_00759 3.6e-192 ydiM EGP Major facilitator Superfamily
HILGINDI_00760 2.7e-29 yfkK S Belongs to the UPF0435 family
HILGINDI_00761 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HILGINDI_00762 3.5e-52 yfkI S gas vesicle protein
HILGINDI_00763 1.5e-144 yihY S Belongs to the UPF0761 family
HILGINDI_00764 2.5e-07
HILGINDI_00765 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HILGINDI_00766 1.3e-185 cax P COG0387 Ca2 H antiporter
HILGINDI_00767 2.5e-144 yfkD S YfkD-like protein
HILGINDI_00768 3.3e-147 yfkC M Mechanosensitive ion channel
HILGINDI_00769 6e-221 yfkA S YfkB-like domain
HILGINDI_00770 4.9e-27 yfjT
HILGINDI_00771 9e-155 pdaA G deacetylase
HILGINDI_00772 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HILGINDI_00773 1.5e-33
HILGINDI_00774 1.7e-184 corA P Mediates influx of magnesium ions
HILGINDI_00775 2.6e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HILGINDI_00776 6.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HILGINDI_00777 7.8e-51 S YfzA-like protein
HILGINDI_00778 3.7e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HILGINDI_00779 1.4e-89 yfjM S Psort location Cytoplasmic, score
HILGINDI_00780 2.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HILGINDI_00781 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HILGINDI_00782 1.8e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HILGINDI_00783 6e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HILGINDI_00784 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HILGINDI_00785 7.2e-15 sspH S Belongs to the SspH family
HILGINDI_00786 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HILGINDI_00787 1.1e-138 glvR F Helix-turn-helix domain, rpiR family
HILGINDI_00788 8.3e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILGINDI_00789 0.0 yfiB3 V ABC transporter
HILGINDI_00790 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HILGINDI_00791 7e-63 mhqP S DoxX
HILGINDI_00792 5.9e-160 yfiE 1.13.11.2 S glyoxalase
HILGINDI_00793 8.5e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HILGINDI_00794 1.7e-96 padR K transcriptional
HILGINDI_00795 1.9e-112 1.6.5.2 S NADPH-dependent FMN reductase
HILGINDI_00796 5.3e-182 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HILGINDI_00797 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
HILGINDI_00798 1.3e-44 yrdF K ribonuclease inhibitor
HILGINDI_00799 1.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
HILGINDI_00800 3e-290 yfiU EGP Major facilitator Superfamily
HILGINDI_00801 2.8e-82 yfiV K transcriptional
HILGINDI_00802 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HILGINDI_00804 4.1e-144 yfhB 5.3.3.17 S PhzF family
HILGINDI_00805 3.3e-106 yfhC C nitroreductase
HILGINDI_00806 2.1e-25 yfhD S YfhD-like protein
HILGINDI_00808 1.8e-167 yfhF S nucleoside-diphosphate sugar epimerase
HILGINDI_00809 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HILGINDI_00810 8.8e-53 yfhH S Protein of unknown function (DUF1811)
HILGINDI_00811 2.6e-206 yfhI EGP Major facilitator Superfamily
HILGINDI_00813 4.8e-168 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HILGINDI_00814 2.2e-44 yfhJ S WVELL protein
HILGINDI_00815 1.6e-94 batE T Bacterial SH3 domain homologues
HILGINDI_00816 3.3e-34 yfhL S SdpI/YhfL protein family
HILGINDI_00817 4.8e-170 yfhM S Alpha/beta hydrolase family
HILGINDI_00818 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HILGINDI_00819 0.0 yfhO S Bacterial membrane protein YfhO
HILGINDI_00820 1e-184 yfhP S membrane-bound metal-dependent
HILGINDI_00821 2.7e-210 mutY L A G-specific
HILGINDI_00822 8.2e-37 yfhS
HILGINDI_00823 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_00825 1.5e-37 ygaB S YgaB-like protein
HILGINDI_00826 1.1e-103 ygaC J Belongs to the UPF0374 family
HILGINDI_00827 2.5e-306 ygaD V ABC transporter
HILGINDI_00828 3.2e-179 ygaE S Membrane
HILGINDI_00829 2.3e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HILGINDI_00830 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
HILGINDI_00831 1.8e-80 perR P Belongs to the Fur family
HILGINDI_00832 1.5e-56 ygzB S UPF0295 protein
HILGINDI_00833 3.7e-165 ygxA S Nucleotidyltransferase-like
HILGINDI_00838 7.8e-08
HILGINDI_00846 1.6e-08
HILGINDI_00850 6.1e-288 C Na+/H+ antiporter family
HILGINDI_00851 9.5e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HILGINDI_00852 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HILGINDI_00853 7.5e-267 ygaK C Berberine and berberine like
HILGINDI_00855 7e-229 oppA5 E PFAM extracellular solute-binding protein family 5
HILGINDI_00856 1.6e-137 appB P Binding-protein-dependent transport system inner membrane component
HILGINDI_00857 9.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILGINDI_00858 1.3e-134 oppD3 P Belongs to the ABC transporter superfamily
HILGINDI_00859 6.2e-134 oppF3 E Belongs to the ABC transporter superfamily
HILGINDI_00860 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HILGINDI_00861 1.7e-184 S Amidohydrolase
HILGINDI_00862 4.2e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HILGINDI_00863 1.1e-181 ssuA M Sulfonate ABC transporter
HILGINDI_00864 4e-145 ssuC P ABC transporter (permease)
HILGINDI_00865 8.5e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HILGINDI_00866 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HILGINDI_00867 6.6e-81 ygaO
HILGINDI_00868 1.4e-22 K Transcriptional regulator
HILGINDI_00870 5.1e-113 yhzB S B3/4 domain
HILGINDI_00871 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HILGINDI_00872 1.1e-175 yhbB S Putative amidase domain
HILGINDI_00873 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HILGINDI_00874 1e-108 yhbD K Protein of unknown function (DUF4004)
HILGINDI_00875 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HILGINDI_00876 1.3e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HILGINDI_00878 0.0 prkA T Ser protein kinase
HILGINDI_00879 2.7e-216 yhbH S Belongs to the UPF0229 family
HILGINDI_00880 4.6e-74 yhbI K DNA-binding transcription factor activity
HILGINDI_00881 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
HILGINDI_00882 8.4e-285 yhcA EGP Major facilitator Superfamily
HILGINDI_00883 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
HILGINDI_00884 3.8e-55 yhcC
HILGINDI_00885 3.3e-53
HILGINDI_00886 2.5e-62 yhcF K Transcriptional regulator
HILGINDI_00887 3e-125 yhcG V ABC transporter, ATP-binding protein
HILGINDI_00888 4.1e-167 yhcH V ABC transporter, ATP-binding protein
HILGINDI_00889 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HILGINDI_00890 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
HILGINDI_00891 3.7e-117 metQ M Belongs to the nlpA lipoprotein family
HILGINDI_00892 1e-193 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HILGINDI_00893 1.1e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HILGINDI_00894 4.2e-54 yhcM
HILGINDI_00895 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HILGINDI_00896 8.6e-162 yhcP
HILGINDI_00897 5.8e-115 yhcQ M Spore coat protein
HILGINDI_00898 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
HILGINDI_00899 3.1e-107 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HILGINDI_00900 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HILGINDI_00901 8.4e-69 yhcU S Family of unknown function (DUF5365)
HILGINDI_00902 2.6e-68 yhcV S COG0517 FOG CBS domain
HILGINDI_00903 1.4e-124 yhcW 5.4.2.6 S hydrolase
HILGINDI_00904 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HILGINDI_00905 3.8e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HILGINDI_00906 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HILGINDI_00907 3.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HILGINDI_00908 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HILGINDI_00909 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HILGINDI_00910 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HILGINDI_00911 9.4e-206 yhcY 2.7.13.3 T Histidine kinase
HILGINDI_00912 5.9e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILGINDI_00913 8.8e-90 azr 1.7.1.6 S NADPH-dependent FMN reductase
HILGINDI_00914 2.5e-39 yhdB S YhdB-like protein
HILGINDI_00915 4e-53 yhdC S Protein of unknown function (DUF3889)
HILGINDI_00916 1.7e-212 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HILGINDI_00917 5.6e-74 nsrR K Transcriptional regulator
HILGINDI_00918 3.8e-255 ygxB M Conserved TM helix
HILGINDI_00919 1.2e-271 ycgB S Stage V sporulation protein R
HILGINDI_00920 9.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HILGINDI_00921 4.8e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HILGINDI_00922 9e-164 citR K Transcriptional regulator
HILGINDI_00923 4.9e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
HILGINDI_00924 5.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_00925 5.3e-251 yhdG E amino acid
HILGINDI_00926 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HILGINDI_00927 8.1e-45 yhdK S Sigma-M inhibitor protein
HILGINDI_00928 8.6e-201 yhdL S Sigma factor regulator N-terminal
HILGINDI_00929 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HILGINDI_00930 1.3e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HILGINDI_00931 8.1e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HILGINDI_00932 4.3e-71 cueR K transcriptional
HILGINDI_00933 2.5e-225 yhdR 2.6.1.1 E Aminotransferase
HILGINDI_00934 5.6e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HILGINDI_00935 3.5e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HILGINDI_00936 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HILGINDI_00937 6.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HILGINDI_00938 3.8e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HILGINDI_00940 1.6e-205 yhdY M Mechanosensitive ion channel
HILGINDI_00941 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HILGINDI_00942 1e-156 yheN G deacetylase
HILGINDI_00943 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HILGINDI_00944 4.6e-88 pksA K Transcriptional regulator
HILGINDI_00945 1.2e-94 ymcC S Membrane
HILGINDI_00946 2.1e-85 T universal stress protein
HILGINDI_00948 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HILGINDI_00949 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HILGINDI_00950 2.1e-111 yheG GM NAD(P)H-binding
HILGINDI_00952 5.8e-29 sspB S spore protein
HILGINDI_00953 1.7e-36 yheE S Family of unknown function (DUF5342)
HILGINDI_00954 2.5e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HILGINDI_00955 4.8e-215 yheC HJ YheC/D like ATP-grasp
HILGINDI_00956 4.2e-206 yheB S Belongs to the UPF0754 family
HILGINDI_00957 9.8e-53 yheA S Belongs to the UPF0342 family
HILGINDI_00958 1.4e-204 yhaZ L DNA alkylation repair enzyme
HILGINDI_00959 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
HILGINDI_00960 9.3e-294 hemZ H coproporphyrinogen III oxidase
HILGINDI_00961 2.4e-250 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HILGINDI_00962 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HILGINDI_00963 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HILGINDI_00965 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
HILGINDI_00966 2.8e-14 S YhzD-like protein
HILGINDI_00967 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HILGINDI_00968 6.1e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HILGINDI_00969 2.6e-238 yhaO L DNA repair exonuclease
HILGINDI_00970 0.0 yhaN L AAA domain
HILGINDI_00971 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HILGINDI_00972 1.6e-32 yhaL S Sporulation protein YhaL
HILGINDI_00973 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HILGINDI_00974 1.9e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HILGINDI_00975 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HILGINDI_00976 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HILGINDI_00977 1.2e-189
HILGINDI_00978 1.4e-184 ykvI S membrane
HILGINDI_00979 0.0 clpE O Belongs to the ClpA ClpB family
HILGINDI_00980 1.1e-136 motA N flagellar motor
HILGINDI_00981 2.7e-127 motB N Flagellar motor protein
HILGINDI_00982 1.5e-77 ykvE K transcriptional
HILGINDI_00983 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HILGINDI_00984 3.4e-10 S Spo0E like sporulation regulatory protein
HILGINDI_00985 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HILGINDI_00986 6.1e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HILGINDI_00987 3.7e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HILGINDI_00988 2.3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HILGINDI_00989 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
HILGINDI_00990 2.9e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HILGINDI_00991 3.5e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HILGINDI_00992 4.4e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HILGINDI_00994 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HILGINDI_00995 0.0 kinE 2.7.13.3 T Histidine kinase
HILGINDI_00996 9.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HILGINDI_00997 3e-23 ykzE
HILGINDI_00998 2.9e-114 ydfR S Protein of unknown function (DUF421)
HILGINDI_00999 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
HILGINDI_01000 4.1e-156 htpX O Belongs to the peptidase M48B family
HILGINDI_01001 2.5e-124 ykrK S Domain of unknown function (DUF1836)
HILGINDI_01002 2.5e-26 sspD S small acid-soluble spore protein
HILGINDI_01003 8.1e-120 rsgI S Anti-sigma factor N-terminus
HILGINDI_01004 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILGINDI_01005 9.2e-136 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HILGINDI_01006 2e-100 ykoX S membrane-associated protein
HILGINDI_01007 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HILGINDI_01008 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HILGINDI_01009 3.7e-99 ykoP G polysaccharide deacetylase
HILGINDI_01010 1.1e-80 ykoM K transcriptional
HILGINDI_01011 3.1e-26 ykoL
HILGINDI_01012 1.9e-16
HILGINDI_01013 5.4e-53 tnrA K transcriptional
HILGINDI_01014 2.2e-238 mgtE P Acts as a magnesium transporter
HILGINDI_01016 3e-245 ydhD M Glycosyl hydrolase
HILGINDI_01017 3.4e-98 ykoE S ABC-type cobalt transport system, permease component
HILGINDI_01018 1.7e-304 P ABC transporter, ATP-binding protein
HILGINDI_01019 3.5e-132 ykoC P Cobalt transport protein
HILGINDI_01020 5.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HILGINDI_01021 1e-176 isp O Belongs to the peptidase S8 family
HILGINDI_01022 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HILGINDI_01023 1.6e-120 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HILGINDI_01024 3.6e-216 hcaT 1.5.1.2 EGP Major facilitator Superfamily
HILGINDI_01025 1.8e-129 M PFAM Collagen triple helix repeat (20 copies)
HILGINDI_01026 3.1e-217 M Glycosyl transferase family 2
HILGINDI_01028 8.9e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HILGINDI_01029 4.2e-71 ohrB O Organic hydroperoxide resistance protein
HILGINDI_01030 2.2e-85 ohrR K COG1846 Transcriptional regulators
HILGINDI_01031 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HILGINDI_01032 6.2e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HILGINDI_01033 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HILGINDI_01034 2.3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HILGINDI_01035 3.4e-49 ykkD P Multidrug resistance protein
HILGINDI_01036 9.4e-53 ykkC P Multidrug resistance protein
HILGINDI_01037 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HILGINDI_01038 4.1e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HILGINDI_01039 1e-159 ykgA E Amidinotransferase
HILGINDI_01040 1.1e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HILGINDI_01041 4.3e-183 ykfD E Belongs to the ABC transporter superfamily
HILGINDI_01042 1.6e-171 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HILGINDI_01043 1e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HILGINDI_01044 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HILGINDI_01045 0.0 dppE E ABC transporter substrate-binding protein
HILGINDI_01046 1.3e-190 dppD P Belongs to the ABC transporter superfamily
HILGINDI_01047 8.5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILGINDI_01048 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILGINDI_01049 6.5e-156 dppA E D-aminopeptidase
HILGINDI_01051 3.9e-287 yubD P Major Facilitator Superfamily
HILGINDI_01052 1.5e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HILGINDI_01054 3.4e-180 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HILGINDI_01055 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HILGINDI_01056 1.4e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HILGINDI_01057 3.8e-243 steT E amino acid
HILGINDI_01058 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HILGINDI_01059 2e-175 pit P phosphate transporter
HILGINDI_01060 2.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HILGINDI_01061 8.7e-23 spoIISB S Stage II sporulation protein SB
HILGINDI_01062 3.9e-167 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HILGINDI_01063 1.3e-38 xhlB S SPP1 phage holin
HILGINDI_01064 8.7e-38 xhlA S Haemolysin XhlA
HILGINDI_01065 2.5e-138 xepA
HILGINDI_01066 1.7e-30 xkdX
HILGINDI_01068 1.4e-90
HILGINDI_01069 4.2e-27
HILGINDI_01070 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HILGINDI_01071 2.5e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HILGINDI_01072 2.1e-57 xkdS S Protein of unknown function (DUF2634)
HILGINDI_01073 7.2e-32 xkdR S Protein of unknown function (DUF2577)
HILGINDI_01074 8e-161 xkdQ 3.2.1.96 G NLP P60 protein
HILGINDI_01075 3.9e-111 xkdP S Lysin motif
HILGINDI_01076 3.7e-188 xkdO L Transglycosylase SLT domain
HILGINDI_01077 3.4e-19
HILGINDI_01078 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
HILGINDI_01079 2e-74 xkdM S Phage tail tube protein
HILGINDI_01080 1e-225 xkdK S Phage tail sheath C-terminal domain
HILGINDI_01081 8.2e-15
HILGINDI_01082 4.9e-57 xkdJ
HILGINDI_01083 3.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
HILGINDI_01084 4.2e-43 yqbH S Domain of unknown function (DUF3599)
HILGINDI_01085 1.7e-45 yqbG S Protein of unknown function (DUF3199)
HILGINDI_01086 1e-157 xkdG S Phage capsid family
HILGINDI_01087 5.7e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
HILGINDI_01088 7.9e-242 yqbA S portal protein
HILGINDI_01089 7.9e-209 xtmB S phage terminase, large subunit
HILGINDI_01090 6.8e-110 xtmA L phage terminase small subunit
HILGINDI_01091 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HILGINDI_01092 2e-10 yqaO S Phage-like element PBSX protein XtrA
HILGINDI_01095 1e-153 xkdC L Bacterial dnaA protein
HILGINDI_01097 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
HILGINDI_01098 2.5e-109 xkdA E IrrE N-terminal-like domain
HILGINDI_01099 7.9e-08 xkdA E IrrE N-terminal-like domain
HILGINDI_01100 3.6e-111 yjqB S phage-related replication protein
HILGINDI_01101 4.7e-61 yjqA S Bacterial PH domain
HILGINDI_01102 5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HILGINDI_01104 4.9e-215 S response regulator aspartate phosphatase
HILGINDI_01105 2.1e-79 yjoA S DinB family
HILGINDI_01106 3.9e-131 MA20_18170 S membrane transporter protein
HILGINDI_01107 2.2e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HILGINDI_01108 1.6e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HILGINDI_01109 3.4e-183 exuR K transcriptional
HILGINDI_01110 1.1e-253 yjmB G symporter YjmB
HILGINDI_01111 4.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
HILGINDI_01112 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HILGINDI_01113 7e-66 yjlC S Protein of unknown function (DUF1641)
HILGINDI_01114 1.5e-91 yjlB S Cupin domain
HILGINDI_01115 1e-176 yjlA EG Putative multidrug resistance efflux transporter
HILGINDI_01116 4.5e-132 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
HILGINDI_01117 7e-123 ybbM S transport system, permease component
HILGINDI_01118 9.5e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HILGINDI_01119 6.8e-29
HILGINDI_01120 3e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HILGINDI_01121 9.4e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HILGINDI_01122 4.3e-92 yjgD S Protein of unknown function (DUF1641)
HILGINDI_01123 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HILGINDI_01124 2.4e-101 yjgB S Domain of unknown function (DUF4309)
HILGINDI_01125 5.9e-70 T PhoQ Sensor
HILGINDI_01126 7.5e-22 yjfB S Putative motility protein
HILGINDI_01128 4e-105 yhiD S MgtC SapB transporter
HILGINDI_01130 1.5e-145 N Kelch motif
HILGINDI_01131 5.8e-126 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HILGINDI_01132 5.7e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
HILGINDI_01133 4e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HILGINDI_01134 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
HILGINDI_01135 2.4e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HILGINDI_01136 2.2e-218 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HILGINDI_01137 1.4e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HILGINDI_01138 3.1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HILGINDI_01139 7.8e-221 ganA 3.2.1.89 G arabinogalactan
HILGINDI_01140 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
HILGINDI_01141 1.4e-251 yfjF EGP Belongs to the major facilitator superfamily
HILGINDI_01142 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
HILGINDI_01143 1.5e-166 bla 3.5.2.6 V beta-lactamase
HILGINDI_01145 3.5e-59 E Glyoxalase-like domain
HILGINDI_01147 0.0 yobL S Bacterial EndoU nuclease
HILGINDI_01148 2.4e-56
HILGINDI_01150 1.4e-16
HILGINDI_01151 9.3e-30
HILGINDI_01152 1.4e-82 rlfA S Protein of unknown function (DUF3800)
HILGINDI_01154 3.4e-07
HILGINDI_01155 7.7e-124 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HILGINDI_01156 2.6e-60 S Pfam:Phage_holin_4_1
HILGINDI_01160 1.6e-202 sidC L Phage minor structural protein
HILGINDI_01161 1.7e-46
HILGINDI_01162 1.6e-127
HILGINDI_01164 2.5e-25 S Phage tail assembly chaperone protein, TAC
HILGINDI_01165 8.2e-32 N domain, Protein
HILGINDI_01166 2.3e-29 S Protein of unknown function (DUF3168)
HILGINDI_01167 3.6e-38 S Bacteriophage HK97-gp10, putative tail-component
HILGINDI_01168 2.3e-27 S Phage head-tail joining protein
HILGINDI_01169 1.6e-27 S Phage gp6-like head-tail connector protein
HILGINDI_01172 1.3e-144 S Phage capsid family
HILGINDI_01173 1.9e-56 S Domain of unknown function (DUF4355)
HILGINDI_01174 4.8e-91 S Phage Mu protein F like protein
HILGINDI_01175 3.1e-198 S Phage portal protein, SPP1 Gp6-like
HILGINDI_01176 1.2e-185 ps334 S Terminase-like family
HILGINDI_01177 2.3e-83 yqaS L DNA packaging
HILGINDI_01180 1.2e-16 K Transcriptional regulator
HILGINDI_01182 3.9e-12 K Transcriptional regulator
HILGINDI_01184 3.9e-66 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HILGINDI_01187 1.1e-45
HILGINDI_01189 2.7e-14 S YopX protein
HILGINDI_01190 6.2e-51 S dUTPase
HILGINDI_01192 3.6e-167 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HILGINDI_01195 5e-17 yqaO S Phage-like element PBSX protein XtrA
HILGINDI_01197 4.2e-58 rusA L Endodeoxyribonuclease RusA
HILGINDI_01199 7.9e-121 xkdC L IstB-like ATP binding protein
HILGINDI_01200 1.4e-74 3.1.3.16 L DnaD domain protein
HILGINDI_01202 9.9e-69 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HILGINDI_01203 6.2e-99
HILGINDI_01207 4.2e-85
HILGINDI_01208 3.7e-46 S Phage regulatory protein Rha (Phage_pRha)
HILGINDI_01209 3.4e-15 S Helix-turn-helix domain
HILGINDI_01210 1.5e-17 K Helix-turn-helix domain
HILGINDI_01211 3.7e-18 xre K Helix-turn-helix XRE-family like proteins
HILGINDI_01212 1.3e-25 S Short C-terminal domain
HILGINDI_01213 4.4e-49 xkdA E IrrE N-terminal-like domain
HILGINDI_01214 1.1e-175 L Belongs to the 'phage' integrase family
HILGINDI_01216 2.6e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HILGINDI_01217 5.4e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HILGINDI_01218 6.1e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
HILGINDI_01219 7.8e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HILGINDI_01220 1.9e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILGINDI_01221 2.7e-35 K SpoVT / AbrB like domain
HILGINDI_01222 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HILGINDI_01223 5.2e-125 S ABC-2 type transporter
HILGINDI_01224 6.8e-136 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HILGINDI_01225 5.1e-35
HILGINDI_01226 0.0 yjcD 3.6.4.12 L DNA helicase
HILGINDI_01227 3.8e-38 spoVIF S Stage VI sporulation protein F
HILGINDI_01231 5.6e-56 yjcA S Protein of unknown function (DUF1360)
HILGINDI_01232 1.1e-54 cotV S Spore Coat Protein X and V domain
HILGINDI_01233 2.3e-21 cotW
HILGINDI_01234 3.9e-71 cotX S Spore Coat Protein X and V domain
HILGINDI_01235 8.1e-90 cotY S Spore coat protein Z
HILGINDI_01236 2.6e-79 cotZ S Spore coat protein
HILGINDI_01237 3e-89 yjbX S Spore coat protein
HILGINDI_01238 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HILGINDI_01239 2.9e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HILGINDI_01240 3.5e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HILGINDI_01241 2.9e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HILGINDI_01242 1.4e-30 thiS H Thiamine biosynthesis
HILGINDI_01243 2.5e-211 thiO 1.4.3.19 E Glycine oxidase
HILGINDI_01244 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HILGINDI_01245 5.8e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HILGINDI_01246 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HILGINDI_01247 1.2e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HILGINDI_01248 4.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HILGINDI_01249 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HILGINDI_01250 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
HILGINDI_01251 1.6e-61 yjbL S Belongs to the UPF0738 family
HILGINDI_01252 1.4e-96 yjbK S protein conserved in bacteria
HILGINDI_01253 1.1e-116 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HILGINDI_01254 4.8e-72 yjbI S Bacterial-like globin
HILGINDI_01255 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HILGINDI_01256 5.8e-19
HILGINDI_01257 0.0 pepF E oligoendopeptidase F
HILGINDI_01258 8.1e-221 yjbF S Competence protein
HILGINDI_01259 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HILGINDI_01260 3.6e-109 yjbE P Integral membrane protein TerC family
HILGINDI_01261 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HILGINDI_01262 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILGINDI_01263 8e-232 S Putative glycosyl hydrolase domain
HILGINDI_01264 2.5e-172 oppF E Belongs to the ABC transporter superfamily
HILGINDI_01265 2.7e-202 oppD P Belongs to the ABC transporter superfamily
HILGINDI_01266 5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILGINDI_01267 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILGINDI_01268 0.0 oppA E ABC transporter substrate-binding protein
HILGINDI_01269 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HILGINDI_01270 5.5e-146 yjbA S Belongs to the UPF0736 family
HILGINDI_01271 2.7e-140 EGP Transmembrane secretion effector
HILGINDI_01272 1.7e-86 2.1.1.265 H Tellurite resistance protein TehB
HILGINDI_01273 6.1e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILGINDI_01274 5.3e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILGINDI_01275 3.1e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HILGINDI_01276 5e-187 appF E Belongs to the ABC transporter superfamily
HILGINDI_01277 2.2e-182 appD P Belongs to the ABC transporter superfamily
HILGINDI_01278 2.3e-147 yjaZ O Zn-dependent protease
HILGINDI_01279 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HILGINDI_01280 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HILGINDI_01281 5.9e-32 yjzB
HILGINDI_01282 4.3e-26 comZ S ComZ
HILGINDI_01283 7.2e-166 med S Transcriptional activator protein med
HILGINDI_01284 1.5e-106 yjaV
HILGINDI_01285 4.4e-140 yjaU I carboxylic ester hydrolase activity
HILGINDI_01286 1.5e-23 yjzD S Protein of unknown function (DUF2929)
HILGINDI_01287 1.2e-27 yjzC S YjzC-like protein
HILGINDI_01288 2.1e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HILGINDI_01289 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HILGINDI_01290 1.2e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HILGINDI_01291 8.9e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HILGINDI_01292 2.6e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HILGINDI_01293 6.1e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HILGINDI_01294 6.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HILGINDI_01295 1.2e-89 norB G Major Facilitator Superfamily
HILGINDI_01296 3.9e-273 yitY C D-arabinono-1,4-lactone oxidase
HILGINDI_01297 4.1e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HILGINDI_01298 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HILGINDI_01299 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HILGINDI_01300 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HILGINDI_01301 3.5e-07
HILGINDI_01302 4.4e-26 S Protein of unknown function (DUF3813)
HILGINDI_01303 2.9e-81 ipi S Intracellular proteinase inhibitor
HILGINDI_01304 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HILGINDI_01305 4.9e-159 yitS S protein conserved in bacteria
HILGINDI_01307 3.9e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HILGINDI_01308 1.5e-233 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HILGINDI_01309 4.1e-173 yufN S ABC transporter substrate-binding protein PnrA-like
HILGINDI_01310 5.3e-161 cvfB S protein conserved in bacteria
HILGINDI_01311 6.6e-55 yajQ S Belongs to the UPF0234 family
HILGINDI_01312 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HILGINDI_01313 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
HILGINDI_01314 9.5e-59 mcbG S Pentapeptide repeats (9 copies)
HILGINDI_01315 5.7e-192 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILGINDI_01316 1.2e-74 argO S Lysine exporter protein LysE YggA
HILGINDI_01317 3.7e-90 yisT S DinB family
HILGINDI_01318 5.9e-160 yisR K Transcriptional regulator
HILGINDI_01319 1.9e-245 yisQ V Mate efflux family protein
HILGINDI_01320 7.4e-135 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HILGINDI_01321 0.0 asnO 6.3.5.4 E Asparagine synthase
HILGINDI_01322 3.1e-98 yisN S Protein of unknown function (DUF2777)
HILGINDI_01323 1.1e-59 yisL S UPF0344 protein
HILGINDI_01324 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HILGINDI_01325 5e-07 yisI S Spo0E like sporulation regulatory protein
HILGINDI_01326 8.4e-34 gerPA S Spore germination protein
HILGINDI_01327 6.2e-35 gerPB S cell differentiation
HILGINDI_01328 9.1e-62 gerPC S Spore germination protein
HILGINDI_01329 3.1e-23 gerPD S Spore germination protein
HILGINDI_01330 1.2e-62 gerPE S Spore germination protein GerPE
HILGINDI_01331 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
HILGINDI_01332 2.9e-50 yisB V COG1403 Restriction endonuclease
HILGINDI_01333 0.0 sbcC L COG0419 ATPase involved in DNA repair
HILGINDI_01334 7.4e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HILGINDI_01335 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HILGINDI_01336 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HILGINDI_01338 8.9e-44 ydfS S Protein of unknown function (DUF421)
HILGINDI_01339 9.7e-94 yhjR S Rubrerythrin
HILGINDI_01340 7.6e-109 K QacR-like protein, C-terminal region
HILGINDI_01341 1.6e-208 blt EGP Major facilitator Superfamily
HILGINDI_01342 2.8e-181 abrB S membrane
HILGINDI_01343 9.7e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HILGINDI_01344 8.6e-276 yhjG CH FAD binding domain
HILGINDI_01346 1.6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HILGINDI_01347 1.8e-110 yhjE S SNARE associated Golgi protein
HILGINDI_01348 3.2e-59 yhjD
HILGINDI_01349 1.4e-27 yhjC S Protein of unknown function (DUF3311)
HILGINDI_01350 5e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HILGINDI_01351 3.3e-47 S Belongs to the UPF0145 family
HILGINDI_01352 1.6e-42 yhjA S Excalibur calcium-binding domain
HILGINDI_01353 4.2e-127 yrpD S Domain of unknown function, YrpD
HILGINDI_01354 7e-92 mepB S MepB protein
HILGINDI_01355 8.2e-66 frataxin S Domain of unknown function (DU1801)
HILGINDI_01356 3.3e-67 frataxin S Domain of unknown function (DU1801)
HILGINDI_01357 1.9e-109 comK K Competence transcription factor
HILGINDI_01358 1.3e-32 yhzC S IDEAL
HILGINDI_01359 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_01360 9.7e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HILGINDI_01361 9.1e-197 hemAT NT chemotaxis protein
HILGINDI_01362 9.3e-90 bioY S BioY family
HILGINDI_01363 4.3e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HILGINDI_01364 5.5e-203 vraB 2.3.1.9 I Belongs to the thiolase family
HILGINDI_01365 2.6e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HILGINDI_01366 1.2e-155 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HILGINDI_01367 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HILGINDI_01368 1.7e-237 yhfN 3.4.24.84 O Peptidase M48
HILGINDI_01369 1.9e-65 yhfM
HILGINDI_01370 3.4e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HILGINDI_01371 3.1e-113 yhfK GM NmrA-like family
HILGINDI_01372 2.3e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
HILGINDI_01373 9.9e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HILGINDI_01374 7.9e-11 yhfH S YhfH-like protein
HILGINDI_01375 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HILGINDI_01376 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HILGINDI_01378 7.4e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HILGINDI_01379 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
HILGINDI_01380 3.5e-100 yhgD K Transcriptional regulator
HILGINDI_01381 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HILGINDI_01382 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HILGINDI_01383 8.6e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HILGINDI_01384 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HILGINDI_01385 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HILGINDI_01386 1.1e-243 yhfA C membrane
HILGINDI_01387 2.5e-225 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HILGINDI_01388 2.8e-123 ecsC S EcsC protein family
HILGINDI_01389 9.5e-220 ecsB U ABC transporter
HILGINDI_01390 1.1e-135 ecsA V transporter (ATP-binding protein)
HILGINDI_01391 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HILGINDI_01392 1.2e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HILGINDI_01393 6.4e-77 trpP S Tryptophan transporter TrpP
HILGINDI_01394 2e-17
HILGINDI_01395 2.4e-38 yhaH S YtxH-like protein
HILGINDI_01396 8.6e-113 hpr K Negative regulator of protease production and sporulation
HILGINDI_01397 9.9e-55 yhaI S Protein of unknown function (DUF1878)
HILGINDI_01398 9.1e-95 yhaK S Putative zincin peptidase
HILGINDI_01399 1.7e-122 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HILGINDI_01400 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_01401 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
HILGINDI_01402 4.1e-65 yngL S Protein of unknown function (DUF1360)
HILGINDI_01403 3.8e-303 yngK T Glycosyl hydrolase-like 10
HILGINDI_01404 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HILGINDI_01405 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HILGINDI_01406 1.9e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HILGINDI_01407 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HILGINDI_01408 2.5e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HILGINDI_01409 3.4e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HILGINDI_01410 2.4e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HILGINDI_01411 3.2e-104 yngC S SNARE associated Golgi protein
HILGINDI_01412 4.2e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HILGINDI_01413 1.1e-71 yngA S membrane
HILGINDI_01414 4.8e-145 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HILGINDI_01415 3.5e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HILGINDI_01416 1.2e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HILGINDI_01417 3e-130 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HILGINDI_01418 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HILGINDI_01419 1.5e-225 bioI 1.14.14.46 C Cytochrome P450
HILGINDI_01420 3.6e-255 yxjC EG COG2610 H gluconate symporter and related permeases
HILGINDI_01421 4.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HILGINDI_01422 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HILGINDI_01423 6.9e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HILGINDI_01424 5.3e-223 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILGINDI_01425 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_01426 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_01427 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_01428 1.1e-289 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HILGINDI_01429 5.1e-253 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
HILGINDI_01430 2.6e-129 T Transcriptional regulatory protein, C terminal
HILGINDI_01431 1.8e-235 T PhoQ Sensor
HILGINDI_01432 2.4e-50 S Domain of unknown function (DUF4870)
HILGINDI_01433 1.6e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HILGINDI_01434 6.7e-212 S Platelet-activating factor acetylhydrolase, isoform II
HILGINDI_01435 3.8e-12
HILGINDI_01437 2.8e-63 V ABC transporter
HILGINDI_01438 3.9e-83 S Protein of unknown function (DUF1430)
HILGINDI_01439 4.1e-303 yndJ S YndJ-like protein
HILGINDI_01440 3.1e-78 yndH S Domain of unknown function (DUF4166)
HILGINDI_01441 1.8e-158 yndG S DoxX-like family
HILGINDI_01442 1.1e-223 exuT G Sugar (and other) transporter
HILGINDI_01443 1.9e-181 kdgR_1 K transcriptional
HILGINDI_01444 2e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HILGINDI_01445 1e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HILGINDI_01446 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HILGINDI_01447 5.3e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HILGINDI_01448 1e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HILGINDI_01449 3.2e-251 agcS E Sodium alanine symporter
HILGINDI_01450 5.1e-41 ynfC
HILGINDI_01451 4.6e-13
HILGINDI_01452 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HILGINDI_01453 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HILGINDI_01454 1.5e-68 yccU S CoA-binding protein
HILGINDI_01455 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HILGINDI_01456 1.3e-50 yneR S Belongs to the HesB IscA family
HILGINDI_01457 7.5e-54 yneQ
HILGINDI_01458 8.3e-75 yneP S Thioesterase-like superfamily
HILGINDI_01459 2.7e-33 tlp S Belongs to the Tlp family
HILGINDI_01461 3.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HILGINDI_01462 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HILGINDI_01463 7.5e-15 sspO S Belongs to the SspO family
HILGINDI_01464 2.3e-19 sspP S Belongs to the SspP family
HILGINDI_01465 2.9e-63 hspX O Spore coat protein
HILGINDI_01466 8.5e-75 yneK S Protein of unknown function (DUF2621)
HILGINDI_01467 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HILGINDI_01468 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HILGINDI_01469 1.7e-125 ccdA O cytochrome c biogenesis protein
HILGINDI_01470 2.1e-23 ynzD S Spo0E like sporulation regulatory protein
HILGINDI_01471 2.3e-28 yneF S UPF0154 protein
HILGINDI_01472 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
HILGINDI_01473 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HILGINDI_01474 9.8e-33 ynzC S UPF0291 protein
HILGINDI_01475 3.5e-112 yneB L resolvase
HILGINDI_01476 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HILGINDI_01477 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HILGINDI_01478 4.6e-12 yoaW
HILGINDI_01479 2.4e-72 yndM S Protein of unknown function (DUF2512)
HILGINDI_01480 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HILGINDI_01481 1.6e-07
HILGINDI_01482 1.1e-144 yndL S Replication protein
HILGINDI_01483 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HILGINDI_01484 0.0 yobO M Pectate lyase superfamily protein
HILGINDI_01486 2.3e-93 yvgO
HILGINDI_01488 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
HILGINDI_01489 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILGINDI_01490 3.6e-119 ynaE S Domain of unknown function (DUF3885)
HILGINDI_01492 4.8e-37
HILGINDI_01493 3.3e-100 J Acetyltransferase (GNAT) domain
HILGINDI_01494 7.4e-43 yoaP 3.1.3.18 K YoaP-like
HILGINDI_01495 8.9e-89 yoaP 3.1.3.18 K YoaP-like
HILGINDI_01497 9.7e-186 adhP 1.1.1.1 C alcohol dehydrogenase
HILGINDI_01498 5.4e-55 dinB S DinB family
HILGINDI_01499 5.4e-17
HILGINDI_01502 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HILGINDI_01503 7.9e-285 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
HILGINDI_01504 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HILGINDI_01505 3.5e-216 xylR GK ROK family
HILGINDI_01506 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HILGINDI_01507 2.8e-252 xynT G MFS/sugar transport protein
HILGINDI_01509 4.4e-74
HILGINDI_01511 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
HILGINDI_01512 4.3e-68 glnR K transcriptional
HILGINDI_01513 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HILGINDI_01514 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HILGINDI_01515 1.3e-176 spoVK O stage V sporulation protein K
HILGINDI_01516 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HILGINDI_01517 9e-110 ymaB S MutT family
HILGINDI_01518 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HILGINDI_01519 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HILGINDI_01520 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HILGINDI_01521 1.8e-20 ymzA
HILGINDI_01522 2.1e-42
HILGINDI_01523 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HILGINDI_01524 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HILGINDI_01525 1.4e-47 ymaF S YmaF family
HILGINDI_01527 3.1e-48 ebrA P Small Multidrug Resistance protein
HILGINDI_01528 5.2e-54 ebrB P Small Multidrug Resistance protein
HILGINDI_01529 6e-79 ymaD O redox protein, regulator of disulfide bond formation
HILGINDI_01530 4.1e-127 ymaC S Replication protein
HILGINDI_01532 7.5e-255 aprX O Belongs to the peptidase S8 family
HILGINDI_01533 1.4e-62 ymzB
HILGINDI_01534 1e-117 yoaK S Membrane
HILGINDI_01535 2.7e-55 nucB M Deoxyribonuclease NucA/NucB
HILGINDI_01536 9e-231 cypA C Cytochrome P450
HILGINDI_01537 0.0 pks13 HQ Beta-ketoacyl synthase
HILGINDI_01538 0.0 dhbF IQ polyketide synthase
HILGINDI_01539 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HILGINDI_01540 0.0 Q Polyketide synthase of type I
HILGINDI_01541 0.0 rhiB IQ polyketide synthase
HILGINDI_01542 1.1e-138 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HILGINDI_01543 2e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HILGINDI_01544 8.2e-243 pksG 2.3.3.10 I synthase
HILGINDI_01545 1.3e-35 acpK IQ Phosphopantetheine attachment site
HILGINDI_01546 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILGINDI_01547 2.5e-183 pksD Q Acyl transferase domain
HILGINDI_01548 2.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILGINDI_01549 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HILGINDI_01551 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HILGINDI_01552 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HILGINDI_01553 1.7e-88 cotE S Spore coat protein
HILGINDI_01554 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HILGINDI_01555 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HILGINDI_01556 6.1e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HILGINDI_01557 3.5e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HILGINDI_01558 1.2e-36 spoVS S Stage V sporulation protein S
HILGINDI_01559 4.9e-153 ymdB S protein conserved in bacteria
HILGINDI_01560 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
HILGINDI_01561 2.1e-192 pbpX V Beta-lactamase
HILGINDI_01562 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HILGINDI_01563 3.8e-232 cinA 3.5.1.42 S Belongs to the CinA family
HILGINDI_01564 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HILGINDI_01565 1.7e-125 ymfM S protein conserved in bacteria
HILGINDI_01566 3.5e-143 ymfK S Protein of unknown function (DUF3388)
HILGINDI_01567 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
HILGINDI_01568 3.9e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HILGINDI_01569 6.4e-243 ymfH S zinc protease
HILGINDI_01570 1.2e-238 ymfF S Peptidase M16
HILGINDI_01571 0.0 ydgH S drug exporters of the RND superfamily
HILGINDI_01572 4e-75 K helix_turn_helix multiple antibiotic resistance protein
HILGINDI_01573 2.4e-229 ymfD EGP Major facilitator Superfamily
HILGINDI_01574 1.8e-133 ymfC K Transcriptional regulator
HILGINDI_01575 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HILGINDI_01576 6.3e-31 S YlzJ-like protein
HILGINDI_01577 2.9e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HILGINDI_01578 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HILGINDI_01579 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HILGINDI_01580 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HILGINDI_01581 2.6e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HILGINDI_01582 1.7e-105 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HILGINDI_01583 1.2e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HILGINDI_01584 2.6e-42 ymxH S YlmC YmxH family
HILGINDI_01585 3.6e-235 pepR S Belongs to the peptidase M16 family
HILGINDI_01586 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HILGINDI_01587 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HILGINDI_01588 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HILGINDI_01589 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HILGINDI_01590 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HILGINDI_01591 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HILGINDI_01592 3.9e-44 ylxP S protein conserved in bacteria
HILGINDI_01593 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HILGINDI_01594 1.8e-47 ylxQ J ribosomal protein
HILGINDI_01595 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
HILGINDI_01596 5.4e-206 nusA K Participates in both transcription termination and antitermination
HILGINDI_01597 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HILGINDI_01598 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HILGINDI_01599 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HILGINDI_01600 1.5e-233 rasP M zinc metalloprotease
HILGINDI_01601 7.3e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HILGINDI_01602 9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
HILGINDI_01603 2.9e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HILGINDI_01604 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HILGINDI_01605 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HILGINDI_01606 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HILGINDI_01607 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HILGINDI_01608 1.5e-53 ylxL
HILGINDI_01609 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILGINDI_01610 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HILGINDI_01611 1.6e-109 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HILGINDI_01612 2.5e-80 cheW NT COG0835 Chemotaxis signal transduction protein
HILGINDI_01613 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HILGINDI_01614 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HILGINDI_01615 5.9e-155 flhG D Belongs to the ParA family
HILGINDI_01616 6.7e-193 flhF N Flagellar biosynthesis regulator FlhF
HILGINDI_01617 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HILGINDI_01618 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HILGINDI_01619 5.2e-131 fliR N Flagellar biosynthetic protein FliR
HILGINDI_01620 2e-37 fliQ N Role in flagellar biosynthesis
HILGINDI_01621 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
HILGINDI_01622 1.9e-110 fliZ N Flagellar biosynthesis protein, FliO
HILGINDI_01623 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HILGINDI_01624 1e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HILGINDI_01625 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HILGINDI_01626 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
HILGINDI_01627 4e-139 flgG N Flagellar basal body rod
HILGINDI_01628 4.2e-64 flgD N Flagellar basal body rod modification protein
HILGINDI_01629 7.2e-205 fliK N Flagellar hook-length control protein
HILGINDI_01630 4.4e-48 ylxF S MgtE intracellular N domain
HILGINDI_01631 4.5e-71 fliJ N Flagellar biosynthesis chaperone
HILGINDI_01632 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HILGINDI_01633 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HILGINDI_01634 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HILGINDI_01635 1.4e-263 fliF N The M ring may be actively involved in energy transduction
HILGINDI_01636 2.5e-31 fliE N Flagellar hook-basal body
HILGINDI_01637 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
HILGINDI_01638 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HILGINDI_01639 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HILGINDI_01640 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HILGINDI_01641 2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HILGINDI_01642 7.2e-172 xerC L tyrosine recombinase XerC
HILGINDI_01643 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HILGINDI_01644 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HILGINDI_01645 1.1e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HILGINDI_01646 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HILGINDI_01647 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HILGINDI_01648 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HILGINDI_01649 1.1e-306 ylqG
HILGINDI_01650 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HILGINDI_01651 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HILGINDI_01652 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HILGINDI_01653 5.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HILGINDI_01654 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HILGINDI_01655 1.3e-61 ylqD S YlqD protein
HILGINDI_01656 1.7e-35 ylqC S Belongs to the UPF0109 family
HILGINDI_01657 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HILGINDI_01658 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HILGINDI_01659 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HILGINDI_01660 6.7e-139 S Phosphotransferase enzyme family
HILGINDI_01661 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HILGINDI_01662 0.0 smc D Required for chromosome condensation and partitioning
HILGINDI_01663 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HILGINDI_01664 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HILGINDI_01665 4.6e-129 IQ reductase
HILGINDI_01666 7.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILGINDI_01667 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HILGINDI_01668 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HILGINDI_01669 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HILGINDI_01670 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HILGINDI_01671 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HILGINDI_01672 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
HILGINDI_01673 5.5e-59 asp S protein conserved in bacteria
HILGINDI_01674 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HILGINDI_01675 3.8e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
HILGINDI_01676 2.3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HILGINDI_01677 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HILGINDI_01678 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HILGINDI_01679 1.9e-138 stp 3.1.3.16 T phosphatase
HILGINDI_01680 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HILGINDI_01681 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HILGINDI_01682 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HILGINDI_01683 1.7e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HILGINDI_01684 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HILGINDI_01685 2.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HILGINDI_01686 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HILGINDI_01687 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HILGINDI_01688 1.5e-40 ylzA S Belongs to the UPF0296 family
HILGINDI_01689 1e-154 yloC S stress-induced protein
HILGINDI_01690 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HILGINDI_01691 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HILGINDI_01692 2.2e-79 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HILGINDI_01693 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HILGINDI_01694 1.4e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HILGINDI_01695 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HILGINDI_01696 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HILGINDI_01697 1.7e-177 cysP P phosphate transporter
HILGINDI_01698 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HILGINDI_01699 4.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HILGINDI_01700 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HILGINDI_01701 1.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HILGINDI_01702 7.7e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HILGINDI_01703 0.0 carB 6.3.5.5 F Belongs to the CarB family
HILGINDI_01704 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HILGINDI_01705 9.5e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HILGINDI_01706 6.9e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HILGINDI_01707 8e-233 pyrP F Xanthine uracil
HILGINDI_01708 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HILGINDI_01709 1.8e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HILGINDI_01710 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HILGINDI_01711 3.4e-64 dksA T COG1734 DnaK suppressor protein
HILGINDI_01712 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HILGINDI_01713 8.9e-68 divIVA D Cell division initiation protein
HILGINDI_01714 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HILGINDI_01715 5.2e-41 yggT S membrane
HILGINDI_01716 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HILGINDI_01717 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HILGINDI_01718 3.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HILGINDI_01719 2.2e-38 ylmC S sporulation protein
HILGINDI_01720 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
HILGINDI_01721 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HILGINDI_01722 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILGINDI_01723 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILGINDI_01724 9.8e-161 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HILGINDI_01725 0.0 bpr O COG1404 Subtilisin-like serine proteases
HILGINDI_01726 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HILGINDI_01727 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HILGINDI_01728 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HILGINDI_01729 3.7e-168 murB 1.3.1.98 M cell wall formation
HILGINDI_01730 4.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HILGINDI_01731 4.8e-185 spoVE D Belongs to the SEDS family
HILGINDI_01732 7.7e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HILGINDI_01733 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HILGINDI_01734 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HILGINDI_01735 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HILGINDI_01736 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HILGINDI_01737 2.9e-52 ftsL D Essential cell division protein
HILGINDI_01738 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HILGINDI_01739 8.9e-78 mraZ K Belongs to the MraZ family
HILGINDI_01740 2.3e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HILGINDI_01741 1.1e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HILGINDI_01742 1.2e-88 ylbP K n-acetyltransferase
HILGINDI_01743 4.5e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HILGINDI_01744 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HILGINDI_01745 7.8e-91 yceD S metal-binding, possibly nucleic acid-binding protein
HILGINDI_01746 5.4e-231 ylbM S Belongs to the UPF0348 family
HILGINDI_01747 2.1e-188 ylbL T Belongs to the peptidase S16 family
HILGINDI_01748 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HILGINDI_01749 9.8e-217 ylbJ S Sporulation integral membrane protein YlbJ
HILGINDI_01750 3.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HILGINDI_01751 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
HILGINDI_01753 7.2e-43 ylbG S UPF0298 protein
HILGINDI_01754 1.2e-71 ylbF S Belongs to the UPF0342 family
HILGINDI_01755 8.8e-37 ylbE S YlbE-like protein
HILGINDI_01756 6.5e-56 ylbD S Putative coat protein
HILGINDI_01757 2.1e-199 ylbC S protein with SCP PR1 domains
HILGINDI_01758 2.2e-73 ylbB T COG0517 FOG CBS domain
HILGINDI_01759 8.5e-60 ylbA S YugN-like family
HILGINDI_01760 9.7e-166 ctaG S cytochrome c oxidase
HILGINDI_01761 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HILGINDI_01762 3.1e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HILGINDI_01763 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HILGINDI_01764 1.5e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HILGINDI_01765 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HILGINDI_01766 2.9e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HILGINDI_01767 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HILGINDI_01768 7.7e-214 ftsW D Belongs to the SEDS family
HILGINDI_01769 8.7e-44 ylaN S Belongs to the UPF0358 family
HILGINDI_01770 5.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
HILGINDI_01771 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HILGINDI_01772 3.7e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HILGINDI_01773 5.1e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HILGINDI_01774 1e-33 ylaI S protein conserved in bacteria
HILGINDI_01775 1.7e-48 ylaH S YlaH-like protein
HILGINDI_01776 0.0 typA T GTP-binding protein TypA
HILGINDI_01777 6.7e-24 S Family of unknown function (DUF5325)
HILGINDI_01778 4.4e-40 ylaE
HILGINDI_01779 2.8e-13 sigC S Putative zinc-finger
HILGINDI_01780 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HILGINDI_01781 5.2e-83 ykzC S Acetyltransferase (GNAT) family
HILGINDI_01782 4.2e-152 suhB 3.1.3.25 G Inositol monophosphatase
HILGINDI_01783 9.7e-25 ykzI
HILGINDI_01784 4.9e-119 yktB S Belongs to the UPF0637 family
HILGINDI_01785 1.6e-42 yktA S Belongs to the UPF0223 family
HILGINDI_01786 4.1e-278 speA 4.1.1.19 E Arginine
HILGINDI_01787 2.7e-138 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HILGINDI_01788 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HILGINDI_01789 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HILGINDI_01790 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HILGINDI_01791 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HILGINDI_01792 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HILGINDI_01793 7.9e-210 V Beta-lactamase
HILGINDI_01794 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HILGINDI_01795 0.0 Q Polyketide synthase of type I
HILGINDI_01796 0.0 Q Polyketide synthase of type I
HILGINDI_01797 0.0 Q Polyketide synthase of type I
HILGINDI_01798 0.0 Q Polyketide synthase of type I
HILGINDI_01799 0.0 Q polyketide synthase
HILGINDI_01800 0.0 Q Polyketide synthase of type I
HILGINDI_01801 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILGINDI_01802 6.5e-103 recN L Putative cell-wall binding lipoprotein
HILGINDI_01804 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HILGINDI_01805 3.9e-147 ykrA S hydrolases of the HAD superfamily
HILGINDI_01806 8.2e-31 ykzG S Belongs to the UPF0356 family
HILGINDI_01807 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HILGINDI_01808 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HILGINDI_01809 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HILGINDI_01810 2e-149 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HILGINDI_01811 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HILGINDI_01812 2.1e-45 abrB K of stationary sporulation gene expression
HILGINDI_01813 6.9e-184 mreB D Rod-share determining protein MreBH
HILGINDI_01814 7.2e-12 S Uncharacterized protein YkpC
HILGINDI_01815 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HILGINDI_01816 5.3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HILGINDI_01817 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HILGINDI_01818 9.8e-37 ykoA
HILGINDI_01819 4.3e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HILGINDI_01820 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HILGINDI_01821 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HILGINDI_01822 4.1e-133 fruR K Transcriptional regulator
HILGINDI_01823 2.4e-212 yknZ V ABC transporter (permease)
HILGINDI_01824 6.1e-123 macB V ABC transporter, ATP-binding protein
HILGINDI_01825 2.6e-171 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HILGINDI_01826 1.3e-104 yknW S Yip1 domain
HILGINDI_01827 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HILGINDI_01828 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HILGINDI_01829 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HILGINDI_01830 3.2e-242 moeA 2.10.1.1 H molybdopterin
HILGINDI_01831 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HILGINDI_01832 5.7e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HILGINDI_01833 4.3e-162 yknT
HILGINDI_01834 1.5e-98 rok K Repressor of ComK
HILGINDI_01835 5.5e-80 ykuV CO thiol-disulfide
HILGINDI_01836 4.9e-140 ykuT M Mechanosensitive ion channel
HILGINDI_01837 4.8e-38 ykuS S Belongs to the UPF0180 family
HILGINDI_01838 5.3e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HILGINDI_01839 1.7e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HILGINDI_01840 1e-78 fld C Flavodoxin
HILGINDI_01841 1.9e-169 ykuO
HILGINDI_01842 1.3e-89 fld C Flavodoxin
HILGINDI_01843 2.3e-167 ccpC K Transcriptional regulator
HILGINDI_01844 2.3e-75 ykuL S CBS domain
HILGINDI_01845 2.5e-26 ykzF S Antirepressor AbbA
HILGINDI_01846 1.7e-93 ykuK S Ribonuclease H-like
HILGINDI_01847 3.9e-37 ykuJ S protein conserved in bacteria
HILGINDI_01848 1.5e-233 ykuI T Diguanylate phosphodiesterase
HILGINDI_01849 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_01850 6.1e-157 ykuE S Metallophosphoesterase
HILGINDI_01851 1.3e-87 ykuD S protein conserved in bacteria
HILGINDI_01852 1.7e-240 ykuC EGP Major facilitator Superfamily
HILGINDI_01853 1.4e-83 ykyB S YkyB-like protein
HILGINDI_01854 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
HILGINDI_01855 2.3e-09
HILGINDI_01856 3.9e-215 patA 2.6.1.1 E Aminotransferase
HILGINDI_01857 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
HILGINDI_01858 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HILGINDI_01859 2.4e-112 ykwD J protein with SCP PR1 domains
HILGINDI_01860 4.3e-49
HILGINDI_01861 2.8e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HILGINDI_01862 1.9e-262 mcpC NT chemotaxis protein
HILGINDI_01863 7.2e-189 splB 4.1.99.14 L Spore photoproduct lyase
HILGINDI_01864 6.1e-38 splA S Transcriptional regulator
HILGINDI_01865 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HILGINDI_01866 2.1e-39 ptsH G phosphocarrier protein HPr
HILGINDI_01867 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILGINDI_01868 5.1e-156 glcT K antiterminator
HILGINDI_01869 3.9e-176 ykvZ 5.1.1.1 K Transcriptional regulator
HILGINDI_01871 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HILGINDI_01872 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HILGINDI_01873 2.7e-88 stoA CO thiol-disulfide
HILGINDI_01874 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HILGINDI_01875 6.3e-111 ykvT 3.5.1.28 M Cell Wall Hydrolase
HILGINDI_01876 2.3e-27
HILGINDI_01877 7.8e-25 ykvS S protein conserved in bacteria
HILGINDI_01878 3.5e-45 ykvR S Protein of unknown function (DUF3219)
HILGINDI_01880 6.9e-162 G Glycosyl hydrolases family 18
HILGINDI_01881 3e-34 3.5.1.104 M LysM domain
HILGINDI_01882 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
HILGINDI_01883 1.4e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HILGINDI_01884 1.1e-86 IQ Enoyl-(Acyl carrier protein) reductase
HILGINDI_01885 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_01886 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_01887 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_01888 4.7e-221 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HILGINDI_01889 2.3e-165 cgeB S Spore maturation protein
HILGINDI_01890 1.2e-52 cgeA
HILGINDI_01891 2.5e-41 cgeC
HILGINDI_01892 1.6e-246 cgeD M maturation of the outermost layer of the spore
HILGINDI_01893 8.3e-145 yiiD K acetyltransferase
HILGINDI_01895 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
HILGINDI_01896 1.4e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HILGINDI_01897 1.1e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HILGINDI_01898 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HILGINDI_01899 1.5e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
HILGINDI_01900 2.8e-157 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HILGINDI_01901 3.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
HILGINDI_01902 1.4e-46 yokU S YokU-like protein, putative antitoxin
HILGINDI_01903 4.1e-36 yozE S Belongs to the UPF0346 family
HILGINDI_01904 1.7e-125 yodN
HILGINDI_01906 6.2e-24 yozD S YozD-like protein
HILGINDI_01907 8e-103 yodM 3.6.1.27 I Acid phosphatase homologues
HILGINDI_01908 8.6e-56 yodL S YodL-like
HILGINDI_01910 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HILGINDI_01911 5.1e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HILGINDI_01912 1.2e-33 yodI
HILGINDI_01913 2.8e-128 yodH Q Methyltransferase
HILGINDI_01914 1.2e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HILGINDI_01915 4.4e-132 yydK K Transcriptional regulator
HILGINDI_01916 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HILGINDI_01917 9.4e-283 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
HILGINDI_01918 3.5e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HILGINDI_01919 1.4e-19 S Protein of unknown function (DUF3311)
HILGINDI_01920 3.8e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HILGINDI_01921 7.9e-111 mhqD S Carboxylesterase
HILGINDI_01922 4.5e-106 yodC C nitroreductase
HILGINDI_01923 1.4e-56 yodB K transcriptional
HILGINDI_01924 5.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
HILGINDI_01925 1.6e-67 yodA S tautomerase
HILGINDI_01927 1.1e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
HILGINDI_01928 7.8e-163 rarD S -transporter
HILGINDI_01929 4.9e-23
HILGINDI_01930 3.7e-60 yojF S Protein of unknown function (DUF1806)
HILGINDI_01931 2.5e-126 yojG S deacetylase
HILGINDI_01932 1.6e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HILGINDI_01933 9.7e-242 norM V Multidrug efflux pump
HILGINDI_01935 9.1e-110 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HILGINDI_01936 7.4e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HILGINDI_01937 9.5e-228 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HILGINDI_01938 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HILGINDI_01939 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
HILGINDI_01940 0.0 yojO P Von Willebrand factor
HILGINDI_01941 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HILGINDI_01942 2.7e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HILGINDI_01943 1.3e-142 S Metallo-beta-lactamase superfamily
HILGINDI_01944 2.7e-161 yocS S -transporter
HILGINDI_01945 1.9e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HILGINDI_01946 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
HILGINDI_01947 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HILGINDI_01948 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HILGINDI_01949 1.6e-31 yozC
HILGINDI_01951 2.4e-56 yozO S Bacterial PH domain
HILGINDI_01952 8.5e-37 yocN
HILGINDI_01953 3.8e-44 yozN
HILGINDI_01954 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
HILGINDI_01955 1.7e-08
HILGINDI_01956 7.8e-10 yocL
HILGINDI_01957 2.5e-54 dksA T general stress protein
HILGINDI_01959 2.8e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HILGINDI_01960 0.0 recQ 3.6.4.12 L DNA helicase
HILGINDI_01961 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
HILGINDI_01963 9.9e-188 yocD 3.4.17.13 V peptidase S66
HILGINDI_01964 1.9e-94 yocC
HILGINDI_01965 1.1e-139 yocB J Protein required for attachment to host cells
HILGINDI_01966 6.9e-90 yozB S membrane
HILGINDI_01967 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HILGINDI_01968 3.4e-55 czrA K transcriptional
HILGINDI_01969 4.2e-92 yobW
HILGINDI_01970 1.9e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HILGINDI_01971 8.3e-94 yobS K Transcriptional regulator
HILGINDI_01972 5.6e-132 yobQ K helix_turn_helix, arabinose operon control protein
HILGINDI_01973 1.9e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HILGINDI_01974 7.4e-298 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HILGINDI_01975 8.2e-84 S SMI1-KNR4 cell-wall
HILGINDI_01976 4.6e-43
HILGINDI_01977 1e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
HILGINDI_01979 1.8e-25 yoaF
HILGINDI_01980 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HILGINDI_01981 1.9e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HILGINDI_01982 6.5e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
HILGINDI_01983 3.2e-183 yoaB EGP Major facilitator Superfamily
HILGINDI_01984 1.1e-138 yoxB
HILGINDI_01985 5.7e-41 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HILGINDI_01986 8.9e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HILGINDI_01987 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HILGINDI_01988 8.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HILGINDI_01989 1.1e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HILGINDI_01990 3.9e-146 gltC K Transcriptional regulator
HILGINDI_01991 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HILGINDI_01992 2.9e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HILGINDI_01993 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HILGINDI_01994 5.2e-156 gltR1 K Transcriptional regulator
HILGINDI_01995 2.8e-271 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HILGINDI_01996 1.8e-50 ybzH K Helix-turn-helix domain
HILGINDI_01997 3.6e-200 ybcL EGP Major facilitator Superfamily
HILGINDI_01998 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HILGINDI_01999 1.8e-34 yoeD G Helix-turn-helix domain
HILGINDI_02000 3.5e-97 L Integrase
HILGINDI_02002 2e-97 yoeB S IseA DL-endopeptidase inhibitor
HILGINDI_02003 1.8e-246 yoeA V MATE efflux family protein
HILGINDI_02004 2.6e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
HILGINDI_02005 1.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HILGINDI_02006 3.6e-41 fer C Ferredoxin
HILGINDI_02007 3.9e-198 ypbB 5.1.3.1 S protein conserved in bacteria
HILGINDI_02008 1.1e-272 recQ 3.6.4.12 L DNA helicase
HILGINDI_02009 1.3e-99 ypbD S metal-dependent membrane protease
HILGINDI_02010 4e-75 ypbE M Lysin motif
HILGINDI_02011 5.7e-85 ypbF S Protein of unknown function (DUF2663)
HILGINDI_02012 4.8e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
HILGINDI_02013 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HILGINDI_02014 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HILGINDI_02015 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HILGINDI_02016 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
HILGINDI_02017 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HILGINDI_02018 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HILGINDI_02019 1.6e-61 ypfA M Flagellar protein YcgR
HILGINDI_02020 1.4e-12 S Family of unknown function (DUF5359)
HILGINDI_02021 2.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HILGINDI_02022 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HILGINDI_02023 6.5e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HILGINDI_02024 4.7e-08 S YpzI-like protein
HILGINDI_02025 1.1e-104 yphA
HILGINDI_02026 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HILGINDI_02027 1.5e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HILGINDI_02028 3.3e-16 yphE S Protein of unknown function (DUF2768)
HILGINDI_02029 4.8e-134 yphF
HILGINDI_02030 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HILGINDI_02031 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HILGINDI_02032 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
HILGINDI_02033 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HILGINDI_02034 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HILGINDI_02035 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HILGINDI_02036 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HILGINDI_02037 5.4e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HILGINDI_02038 2.9e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HILGINDI_02039 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HILGINDI_02040 7.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HILGINDI_02041 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HILGINDI_02042 2.4e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HILGINDI_02043 5.3e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HILGINDI_02044 4.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HILGINDI_02045 1.1e-118 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HILGINDI_02046 1.7e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HILGINDI_02047 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HILGINDI_02048 9.3e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HILGINDI_02049 3.5e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HILGINDI_02050 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HILGINDI_02051 2.7e-233 S COG0457 FOG TPR repeat
HILGINDI_02052 2.1e-99 ypiB S Belongs to the UPF0302 family
HILGINDI_02053 2.9e-78 ypiF S Protein of unknown function (DUF2487)
HILGINDI_02054 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HILGINDI_02055 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HILGINDI_02056 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HILGINDI_02057 9.2e-104 ypjA S membrane
HILGINDI_02058 5.1e-142 ypjB S sporulation protein
HILGINDI_02059 1.5e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
HILGINDI_02060 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HILGINDI_02061 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HILGINDI_02062 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HILGINDI_02063 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HILGINDI_02064 5.6e-132 bshB1 S proteins, LmbE homologs
HILGINDI_02065 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HILGINDI_02066 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HILGINDI_02067 5.3e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HILGINDI_02068 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HILGINDI_02069 3.2e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HILGINDI_02070 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HILGINDI_02071 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HILGINDI_02072 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HILGINDI_02073 4e-81 ypmB S protein conserved in bacteria
HILGINDI_02074 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HILGINDI_02075 2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HILGINDI_02076 8.8e-130 dnaD L DNA replication protein DnaD
HILGINDI_02077 1.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HILGINDI_02078 8.2e-90 ypoC
HILGINDI_02079 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HILGINDI_02080 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HILGINDI_02081 2.6e-188 yppC S Protein of unknown function (DUF2515)
HILGINDI_02084 7.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
HILGINDI_02086 1.9e-50 yppG S YppG-like protein
HILGINDI_02087 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HILGINDI_02088 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HILGINDI_02089 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HILGINDI_02090 5e-237 yprB L RNase_H superfamily
HILGINDI_02092 9.9e-33 cotD S Inner spore coat protein D
HILGINDI_02093 1.7e-99 ypsA S Belongs to the UPF0398 family
HILGINDI_02094 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HILGINDI_02095 7.2e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HILGINDI_02096 3.8e-78 yqgA
HILGINDI_02097 6.6e-22 S YpzG-like protein
HILGINDI_02099 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HILGINDI_02100 5.1e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HILGINDI_02101 7.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HILGINDI_02102 1.9e-234 pbuX F xanthine
HILGINDI_02104 7e-101 yrdC 3.5.1.19 Q Isochorismatase family
HILGINDI_02105 9.2e-93 ydfR S Protein of unknown function (DUF421)
HILGINDI_02107 7.5e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HILGINDI_02108 8.8e-110 J Acetyltransferase (GNAT) domain
HILGINDI_02109 4.3e-206 bcsA Q Naringenin-chalcone synthase
HILGINDI_02110 5.5e-89 ypbQ S protein conserved in bacteria
HILGINDI_02111 0.0 ypbR S Dynamin family
HILGINDI_02112 3.5e-39 ypbS S Protein of unknown function (DUF2533)
HILGINDI_02114 4.1e-164 polA 2.7.7.7 L 5'3' exonuclease
HILGINDI_02116 3.9e-66 rnhA 3.1.26.4 L Ribonuclease
HILGINDI_02117 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HILGINDI_02118 2.4e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HILGINDI_02119 7.4e-28 ypeQ S Zinc-finger
HILGINDI_02120 1.2e-36 S Protein of unknown function (DUF2564)
HILGINDI_02121 3.3e-12 degR
HILGINDI_02122 1e-30 cspD K Cold-shock protein
HILGINDI_02123 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HILGINDI_02124 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HILGINDI_02125 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HILGINDI_02126 2.7e-98 ypgQ S phosphohydrolase
HILGINDI_02127 1.2e-157 ypgR C COG0694 Thioredoxin-like proteins and domains
HILGINDI_02128 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HILGINDI_02129 1e-75 yphP S Belongs to the UPF0403 family
HILGINDI_02130 8.2e-129 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HILGINDI_02131 2.7e-114 ypjP S YpjP-like protein
HILGINDI_02132 2.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HILGINDI_02133 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HILGINDI_02134 1.4e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HILGINDI_02135 9.3e-110 hlyIII S protein, Hemolysin III
HILGINDI_02136 2.9e-179 pspF K Transcriptional regulator
HILGINDI_02137 1.4e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HILGINDI_02138 2.6e-39 ypmP S Protein of unknown function (DUF2535)
HILGINDI_02139 2.3e-113 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HILGINDI_02140 2e-135 ypmR E GDSL-like Lipase/Acylhydrolase
HILGINDI_02141 5.5e-98 ypmS S protein conserved in bacteria
HILGINDI_02142 1.4e-66 ypoP K transcriptional
HILGINDI_02143 9.2e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HILGINDI_02144 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HILGINDI_02145 2.3e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
HILGINDI_02146 9.3e-303 yokA L Recombinase
HILGINDI_02149 1.4e-26 yokF 3.1.31.1 L RNA catabolic process
HILGINDI_02150 1.5e-84 G SMI1-KNR4 cell-wall
HILGINDI_02151 2.9e-251 UW nuclease activity
HILGINDI_02152 1.4e-89 yokJ S SMI1 / KNR4 family (SUKH-1)
HILGINDI_02153 1.3e-84 yokK S SMI1 / KNR4 family
HILGINDI_02154 1.2e-26 S Acetyltransferase (GNAT) domain
HILGINDI_02156 5.3e-193 S aspartate phosphatase
HILGINDI_02157 5.6e-77 yoqH M LysM domain
HILGINDI_02166 1.6e-08
HILGINDI_02173 1.3e-09
HILGINDI_02174 7.8e-08
HILGINDI_02183 9e-78 tspO T membrane
HILGINDI_02184 2e-132 dksA T COG1734 DnaK suppressor protein
HILGINDI_02185 6.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
HILGINDI_02186 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HILGINDI_02187 6.5e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HILGINDI_02188 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HILGINDI_02189 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HILGINDI_02190 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HILGINDI_02191 2.3e-24 S Domain of Unknown Function (DUF1540)
HILGINDI_02192 2.6e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HILGINDI_02193 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
HILGINDI_02194 1.6e-41 rpmE2 J Ribosomal protein L31
HILGINDI_02195 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HILGINDI_02196 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HILGINDI_02197 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HILGINDI_02198 2.7e-76 ytkA S YtkA-like
HILGINDI_02200 1.6e-76 dps P Belongs to the Dps family
HILGINDI_02201 1.7e-61 ytkC S Bacteriophage holin family
HILGINDI_02202 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HILGINDI_02203 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HILGINDI_02204 3.2e-144 ytlC P ABC transporter
HILGINDI_02205 8.1e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HILGINDI_02206 3.9e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HILGINDI_02207 1.6e-38 ytmB S Protein of unknown function (DUF2584)
HILGINDI_02208 1.7e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HILGINDI_02209 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HILGINDI_02210 0.0 asnB 6.3.5.4 E Asparagine synthase
HILGINDI_02211 4.3e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HILGINDI_02212 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HILGINDI_02213 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
HILGINDI_02214 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HILGINDI_02215 6.2e-143 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HILGINDI_02217 8.7e-107 ytqB J Putative rRNA methylase
HILGINDI_02218 2.1e-190 yhcC S Fe-S oxidoreductase
HILGINDI_02219 1.5e-284 norB EGP COG0477 Permeases of the major facilitator superfamily
HILGINDI_02220 3.4e-192 K helix_turn_helix, Arsenical Resistance Operon Repressor
HILGINDI_02221 7.4e-40 ytzC S Protein of unknown function (DUF2524)
HILGINDI_02223 3.9e-66 ytrA K GntR family transcriptional regulator
HILGINDI_02224 3.8e-162 ytrB P abc transporter atp-binding protein
HILGINDI_02225 2.3e-168 S ABC-2 family transporter protein
HILGINDI_02226 2.7e-172 P ABC-2 family transporter protein
HILGINDI_02227 6.1e-161
HILGINDI_02228 1.3e-125 ytrE V ABC transporter, ATP-binding protein
HILGINDI_02229 1.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HILGINDI_02230 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_02231 3.9e-168 T PhoQ Sensor
HILGINDI_02232 5.8e-135 bceA V ABC transporter, ATP-binding protein
HILGINDI_02233 0.0 bceB V ABC transporter (permease)
HILGINDI_02234 5.9e-129 ywaF S Integral membrane protein
HILGINDI_02235 7.3e-209 yttB EGP Major facilitator Superfamily
HILGINDI_02236 2.4e-139 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HILGINDI_02237 1.2e-52 ytvB S Protein of unknown function (DUF4257)
HILGINDI_02238 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HILGINDI_02239 2.1e-51 ytwF P Sulfurtransferase
HILGINDI_02240 4.6e-85 M Acetyltransferase (GNAT) domain
HILGINDI_02241 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HILGINDI_02242 1.8e-142 amyC P ABC transporter (permease)
HILGINDI_02243 4.8e-168 amyD G Binding-protein-dependent transport system inner membrane component
HILGINDI_02244 1.6e-246 msmE G Bacterial extracellular solute-binding protein
HILGINDI_02245 4.4e-186 msmR K Transcriptional regulator
HILGINDI_02246 9e-26 yteV S Sporulation protein Cse60
HILGINDI_02247 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HILGINDI_02248 1.3e-235 ytfP S HI0933-like protein
HILGINDI_02249 7.7e-294 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HILGINDI_02250 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HILGINDI_02251 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HILGINDI_02252 1.7e-128 ythP V ABC transporter
HILGINDI_02253 6.4e-218 ythQ U Bacterial ABC transporter protein EcsB
HILGINDI_02254 3.4e-228 pbuO S permease
HILGINDI_02255 1e-270 pepV 3.5.1.18 E Dipeptidase
HILGINDI_02256 3.9e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HILGINDI_02257 6.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HILGINDI_02258 7.5e-169 ytlQ
HILGINDI_02259 1.2e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HILGINDI_02260 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
HILGINDI_02261 3.5e-45 ytzH S YtzH-like protein
HILGINDI_02262 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HILGINDI_02263 1.6e-165 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HILGINDI_02264 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HILGINDI_02265 1.7e-51 ytzB S small secreted protein
HILGINDI_02266 2.2e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HILGINDI_02267 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HILGINDI_02268 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HILGINDI_02269 3.7e-148 ytpQ S Belongs to the UPF0354 family
HILGINDI_02270 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HILGINDI_02271 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HILGINDI_02272 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HILGINDI_02273 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HILGINDI_02274 1.7e-16 ytxH S COG4980 Gas vesicle protein
HILGINDI_02275 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
HILGINDI_02276 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HILGINDI_02277 2.9e-182 ccpA K catabolite control protein A
HILGINDI_02278 5.1e-145 motA N flagellar motor
HILGINDI_02279 3.7e-120 motS N Flagellar motor protein
HILGINDI_02280 2.1e-229 acuC BQ histone deacetylase
HILGINDI_02281 2.5e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
HILGINDI_02282 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HILGINDI_02283 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HILGINDI_02284 9.4e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HILGINDI_02285 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
HILGINDI_02286 2.6e-124 azlC E AzlC protein
HILGINDI_02287 4.4e-149 K Transcriptional regulator
HILGINDI_02288 1.9e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HILGINDI_02289 5.9e-140 E GDSL-like Lipase/Acylhydrolase family
HILGINDI_02291 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
HILGINDI_02292 7.3e-09
HILGINDI_02293 1.7e-221 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HILGINDI_02295 1.9e-40 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HILGINDI_02296 7.5e-18 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HILGINDI_02297 6.2e-46 S HicB_like antitoxin of bacterial toxin-antitoxin system
HILGINDI_02300 1.1e-64 D nuclear chromosome segregation
HILGINDI_02301 1.5e-100 yokH G SMI1 / KNR4 family
HILGINDI_02302 4.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HILGINDI_02303 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HILGINDI_02304 2.7e-284 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HILGINDI_02305 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
HILGINDI_02306 1.7e-108 yttP K Transcriptional regulator
HILGINDI_02307 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HILGINDI_02308 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HILGINDI_02309 4e-240 braB E Component of the transport system for branched-chain amino acids
HILGINDI_02310 1.2e-208 iscS2 2.8.1.7 E Cysteine desulfurase
HILGINDI_02311 7.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HILGINDI_02312 3.9e-31 sspB S spore protein
HILGINDI_02313 6.5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HILGINDI_02314 0.0 ytcJ S amidohydrolase
HILGINDI_02315 1.7e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HILGINDI_02316 4.2e-181 sppA OU signal peptide peptidase SppA
HILGINDI_02317 1.7e-87 yteJ S RDD family
HILGINDI_02318 3.8e-109 ytfI S Protein of unknown function (DUF2953)
HILGINDI_02319 1.6e-60 ytfJ S Sporulation protein YtfJ
HILGINDI_02320 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HILGINDI_02321 1.4e-184 ytxK 2.1.1.72 L DNA methylase
HILGINDI_02322 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HILGINDI_02323 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HILGINDI_02324 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HILGINDI_02325 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
HILGINDI_02327 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_02328 2.5e-129 ytkL S Belongs to the UPF0173 family
HILGINDI_02329 3.7e-238 ytoI K transcriptional regulator containing CBS domains
HILGINDI_02330 2.4e-47 ytpI S YtpI-like protein
HILGINDI_02331 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HILGINDI_02332 4.4e-23
HILGINDI_02333 2.5e-86 ytrI
HILGINDI_02334 3.2e-56 ytrH S Sporulation protein YtrH
HILGINDI_02335 0.0 dnaE 2.7.7.7 L DNA polymerase
HILGINDI_02336 1.3e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
HILGINDI_02337 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HILGINDI_02338 3.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HILGINDI_02339 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HILGINDI_02340 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HILGINDI_02341 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HILGINDI_02342 1.1e-193 ytvI S sporulation integral membrane protein YtvI
HILGINDI_02343 4.3e-72 yeaL S membrane
HILGINDI_02344 3.2e-47 yjdF S Protein of unknown function (DUF2992)
HILGINDI_02345 5.5e-53
HILGINDI_02346 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HILGINDI_02347 3.1e-242 icd 1.1.1.42 C isocitrate
HILGINDI_02348 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HILGINDI_02349 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_02350 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HILGINDI_02351 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HILGINDI_02352 1.6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HILGINDI_02353 9.5e-107 ytaF P Probably functions as a manganese efflux pump
HILGINDI_02354 4e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HILGINDI_02355 1.5e-160 ytbE S reductase
HILGINDI_02356 2.2e-205 ytbD EGP Major facilitator Superfamily
HILGINDI_02357 2e-67 ytcD K Transcriptional regulator
HILGINDI_02358 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HILGINDI_02359 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HILGINDI_02360 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HILGINDI_02361 4.5e-258 dnaB L Membrane attachment protein
HILGINDI_02362 4.3e-172 dnaI L Primosomal protein DnaI
HILGINDI_02363 2.7e-109 ytxB S SNARE associated Golgi protein
HILGINDI_02364 2.3e-153 ytxC S YtxC-like family
HILGINDI_02365 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HILGINDI_02366 2.1e-151 ysaA S HAD-hyrolase-like
HILGINDI_02367 0.0 lytS 2.7.13.3 T Histidine kinase
HILGINDI_02368 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HILGINDI_02369 3.1e-40 lrgA S effector of murein hydrolase LrgA
HILGINDI_02370 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HILGINDI_02371 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HILGINDI_02372 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HILGINDI_02373 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HILGINDI_02374 2e-42 ysdA S Membrane
HILGINDI_02375 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HILGINDI_02376 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
HILGINDI_02377 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HILGINDI_02378 2.8e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HILGINDI_02379 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HILGINDI_02380 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HILGINDI_02381 4.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HILGINDI_02382 1.9e-225 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HILGINDI_02383 1.8e-253 araN G carbohydrate transport
HILGINDI_02384 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
HILGINDI_02385 4.4e-144 araQ G transport system permease
HILGINDI_02386 1.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HILGINDI_02387 0.0 cstA T Carbon starvation protein
HILGINDI_02388 3.4e-255 glcF C Glycolate oxidase
HILGINDI_02389 1.4e-259 glcD 1.1.3.15 C FAD binding domain
HILGINDI_02390 2.6e-205 ysfB KT regulator
HILGINDI_02391 2e-32 sspI S Belongs to the SspI family
HILGINDI_02392 1.4e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HILGINDI_02393 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HILGINDI_02394 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HILGINDI_02395 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HILGINDI_02396 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HILGINDI_02397 1.6e-83 cvpA S membrane protein, required for colicin V production
HILGINDI_02398 0.0 polX L COG1796 DNA polymerase IV (family X)
HILGINDI_02399 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HILGINDI_02400 4.7e-67 yshE S membrane
HILGINDI_02401 2.7e-123 ywbB S Protein of unknown function (DUF2711)
HILGINDI_02402 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HILGINDI_02403 9.2e-104 fadR K Transcriptional regulator
HILGINDI_02404 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HILGINDI_02405 3.3e-138 etfB C Electron transfer flavoprotein
HILGINDI_02406 1.9e-178 etfA C Electron transfer flavoprotein
HILGINDI_02407 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HILGINDI_02408 2.5e-52 trxA O Belongs to the thioredoxin family
HILGINDI_02409 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HILGINDI_02410 7e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HILGINDI_02411 5.9e-79 yslB S Protein of unknown function (DUF2507)
HILGINDI_02412 4.8e-108 sdhC C succinate dehydrogenase
HILGINDI_02413 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HILGINDI_02414 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HILGINDI_02415 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HILGINDI_02416 2e-30 gerE K Transcriptional regulator
HILGINDI_02417 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HILGINDI_02418 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HILGINDI_02419 2.4e-198 gerM S COG5401 Spore germination protein
HILGINDI_02420 1.5e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HILGINDI_02421 2.1e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HILGINDI_02422 2.6e-91 ysnB S Phosphoesterase
HILGINDI_02425 6.3e-56 L Phage integrase family
HILGINDI_02427 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HILGINDI_02428 4.4e-245 hsdM 2.1.1.72 L type I restriction-modification system
HILGINDI_02429 9.2e-83 hsdS 3.1.21.3 L COG0732 Restriction endonuclease S subunits
HILGINDI_02430 8.4e-12 pinR3 L Resolvase, N terminal domain
HILGINDI_02431 6.2e-43 pinR3 L Resolvase, N terminal domain
HILGINDI_02432 5e-27
HILGINDI_02435 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HILGINDI_02436 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
HILGINDI_02437 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HILGINDI_02438 2.1e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HILGINDI_02439 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HILGINDI_02440 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HILGINDI_02441 5.8e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HILGINDI_02442 4.6e-188 ysoA H Tetratricopeptide repeat
HILGINDI_02443 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HILGINDI_02444 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HILGINDI_02445 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HILGINDI_02446 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HILGINDI_02447 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HILGINDI_02448 2.9e-87 ysxD
HILGINDI_02449 7e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HILGINDI_02450 3.6e-146 hemX O cytochrome C
HILGINDI_02451 2.1e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HILGINDI_02452 8.6e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HILGINDI_02453 2.3e-184 hemB 4.2.1.24 H Belongs to the ALAD family
HILGINDI_02454 2.3e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HILGINDI_02455 1.1e-224 spoVID M stage VI sporulation protein D
HILGINDI_02456 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HILGINDI_02457 2.1e-25
HILGINDI_02458 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HILGINDI_02459 6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HILGINDI_02460 1.3e-131 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HILGINDI_02461 8.7e-139 spoIIB S Sporulation related domain
HILGINDI_02462 1.2e-100 maf D septum formation protein Maf
HILGINDI_02463 1.8e-127 radC E Belongs to the UPF0758 family
HILGINDI_02464 4e-184 mreB D Rod shape-determining protein MreB
HILGINDI_02465 1.2e-157 mreC M Involved in formation and maintenance of cell shape
HILGINDI_02466 1.4e-84 mreD M shape-determining protein
HILGINDI_02467 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HILGINDI_02468 8e-143 minD D Belongs to the ParA family
HILGINDI_02469 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HILGINDI_02470 1.2e-160 spoIVFB S Stage IV sporulation protein
HILGINDI_02471 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HILGINDI_02472 3.2e-56 ysxB J ribosomal protein
HILGINDI_02473 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HILGINDI_02474 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HILGINDI_02475 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HILGINDI_02476 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HILGINDI_02477 3.5e-160 pheA 4.2.1.51 E Prephenate dehydratase
HILGINDI_02478 3.2e-95 niaR S small molecule binding protein (contains 3H domain)
HILGINDI_02479 2.7e-224 nifS 2.8.1.7 E Cysteine desulfurase
HILGINDI_02480 1.2e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HILGINDI_02481 2.8e-154 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HILGINDI_02482 2.4e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HILGINDI_02483 8.8e-146 safA M spore coat assembly protein SafA
HILGINDI_02484 3e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HILGINDI_02486 1.2e-91 bofC S BofC C-terminal domain
HILGINDI_02487 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HILGINDI_02488 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HILGINDI_02489 1.6e-20 yrzS S Protein of unknown function (DUF2905)
HILGINDI_02490 1.8e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HILGINDI_02491 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HILGINDI_02492 5.6e-37 yajC U Preprotein translocase subunit YajC
HILGINDI_02493 2.4e-60 yrzE S Protein of unknown function (DUF3792)
HILGINDI_02494 9.5e-110 yrbG S membrane
HILGINDI_02495 2.1e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HILGINDI_02496 1.3e-50 yrzD S Post-transcriptional regulator
HILGINDI_02497 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HILGINDI_02498 9.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HILGINDI_02499 1.1e-45 yrvD S Lipopolysaccharide assembly protein A domain
HILGINDI_02500 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HILGINDI_02501 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HILGINDI_02502 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HILGINDI_02503 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HILGINDI_02504 2.6e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
HILGINDI_02507 2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HILGINDI_02508 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HILGINDI_02509 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HILGINDI_02510 2.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HILGINDI_02511 7.8e-64 cymR K Transcriptional regulator
HILGINDI_02512 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
HILGINDI_02513 7e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HILGINDI_02514 1.7e-18 S COG0457 FOG TPR repeat
HILGINDI_02515 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HILGINDI_02516 2.6e-82 yrrD S protein conserved in bacteria
HILGINDI_02517 2.9e-30 yrzR
HILGINDI_02518 2.1e-08 S Protein of unknown function (DUF3918)
HILGINDI_02519 2.2e-106 glnP P ABC transporter
HILGINDI_02520 1.2e-109 gluC P ABC transporter
HILGINDI_02521 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
HILGINDI_02522 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HILGINDI_02523 6.4e-164 yrrI S AI-2E family transporter
HILGINDI_02524 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HILGINDI_02525 8.5e-41 yrzL S Belongs to the UPF0297 family
HILGINDI_02526 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HILGINDI_02527 7.1e-46 yrzB S Belongs to the UPF0473 family
HILGINDI_02528 5.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HILGINDI_02529 2.1e-117 yrrM 2.1.1.104 S O-methyltransferase
HILGINDI_02530 1.7e-173 yegQ O Peptidase U32
HILGINDI_02531 1.6e-246 yegQ O COG0826 Collagenase and related proteases
HILGINDI_02532 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HILGINDI_02533 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HILGINDI_02534 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HILGINDI_02535 3.1e-69 yrrS S Protein of unknown function (DUF1510)
HILGINDI_02536 4.1e-27 yrzA S Protein of unknown function (DUF2536)
HILGINDI_02537 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HILGINDI_02538 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HILGINDI_02539 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HILGINDI_02540 5.2e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HILGINDI_02541 4.6e-35 yrhC S YrhC-like protein
HILGINDI_02542 7e-81 yrhD S Protein of unknown function (DUF1641)
HILGINDI_02543 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HILGINDI_02544 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HILGINDI_02545 8e-143 focA P Formate nitrite
HILGINDI_02547 1.1e-92 yrhH Q methyltransferase
HILGINDI_02548 1.7e-99 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HILGINDI_02549 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HILGINDI_02550 2.7e-211 ynfM EGP Major facilitator Superfamily
HILGINDI_02551 1.1e-164 yybE K Transcriptional regulator
HILGINDI_02552 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HILGINDI_02553 1.1e-183 romA S Beta-lactamase superfamily domain
HILGINDI_02554 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HILGINDI_02555 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HILGINDI_02556 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HILGINDI_02557 4.5e-129 glvR K Helix-turn-helix domain, rpiR family
HILGINDI_02558 1e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HILGINDI_02559 2.7e-146 S hydrolase
HILGINDI_02561 8.9e-92 yrdA S DinB family
HILGINDI_02562 1.8e-79 yyaR K Acetyltransferase (GNAT) domain
HILGINDI_02563 4.8e-32 tetL EGP Major facilitator Superfamily
HILGINDI_02564 7.7e-32 yyaR K acetyltransferase
HILGINDI_02565 1.1e-98 adk 2.7.4.3 F adenylate kinase activity
HILGINDI_02566 2.4e-148 ydeE K AraC family transcriptional regulator
HILGINDI_02567 4.2e-92 K Transcriptional regulator PadR-like family
HILGINDI_02568 1.9e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HILGINDI_02569 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILGINDI_02570 6.5e-216 EGP Major facilitator Superfamily
HILGINDI_02571 8.4e-26 2.3.1.57 K Acetyltransferase (GNAT) domain
HILGINDI_02572 4.2e-107 yqeD S SNARE associated Golgi protein
HILGINDI_02573 4e-141 3.5.1.104 G Polysaccharide deacetylase
HILGINDI_02574 1.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
HILGINDI_02576 2e-94 yqeG S hydrolase of the HAD superfamily
HILGINDI_02577 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HILGINDI_02578 2.1e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HILGINDI_02579 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HILGINDI_02580 1.1e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HILGINDI_02581 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HILGINDI_02582 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HILGINDI_02583 8.4e-139 yqeM Q Methyltransferase
HILGINDI_02584 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HILGINDI_02585 2.8e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HILGINDI_02586 8e-105 comEB 3.5.4.12 F ComE operon protein 2
HILGINDI_02587 0.0 comEC S Competence protein ComEC
HILGINDI_02588 1.9e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
HILGINDI_02589 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
HILGINDI_02590 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HILGINDI_02591 4.1e-220 spoIIP M stage II sporulation protein P
HILGINDI_02592 7.9e-52 yqxA S Protein of unknown function (DUF3679)
HILGINDI_02593 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HILGINDI_02594 1.4e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HILGINDI_02595 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HILGINDI_02596 7.9e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HILGINDI_02597 0.0 dnaK O Heat shock 70 kDa protein
HILGINDI_02598 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HILGINDI_02599 4.6e-174 prmA J Methylates ribosomal protein L11
HILGINDI_02600 4.4e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HILGINDI_02601 1e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HILGINDI_02602 1.6e-158 yqeW P COG1283 Na phosphate symporter
HILGINDI_02603 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HILGINDI_02604 1.2e-68 yqeY S Yqey-like protein
HILGINDI_02605 2.8e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HILGINDI_02606 1.6e-121 yqfA S UPF0365 protein
HILGINDI_02607 3.4e-55 yqfB
HILGINDI_02608 9.3e-46 yqfC S sporulation protein YqfC
HILGINDI_02609 4.4e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HILGINDI_02610 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
HILGINDI_02611 0.0 yqfF S membrane-associated HD superfamily hydrolase
HILGINDI_02612 2.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HILGINDI_02613 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HILGINDI_02614 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HILGINDI_02615 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HILGINDI_02616 1.8e-16 S YqzL-like protein
HILGINDI_02617 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
HILGINDI_02618 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HILGINDI_02619 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HILGINDI_02620 4.5e-112 ccpN K CBS domain
HILGINDI_02621 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HILGINDI_02622 6.1e-88 yaiI S Belongs to the UPF0178 family
HILGINDI_02623 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HILGINDI_02624 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HILGINDI_02625 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
HILGINDI_02626 8.4e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HILGINDI_02627 4.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HILGINDI_02628 2.5e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HILGINDI_02629 3.7e-46 yqfQ S YqfQ-like protein
HILGINDI_02630 3e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HILGINDI_02631 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HILGINDI_02632 7.9e-36 yqfT S Protein of unknown function (DUF2624)
HILGINDI_02633 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HILGINDI_02634 2.9e-72 zur P Belongs to the Fur family
HILGINDI_02635 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HILGINDI_02636 2.3e-52 yqfX S membrane
HILGINDI_02637 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HILGINDI_02638 8.2e-48 yqfZ M LysM domain
HILGINDI_02639 8.7e-131 yqgB S Protein of unknown function (DUF1189)
HILGINDI_02640 6e-77 yqgC S protein conserved in bacteria
HILGINDI_02641 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HILGINDI_02642 2e-228 yqgE EGP Major facilitator superfamily
HILGINDI_02643 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HILGINDI_02644 1.7e-157 pstS P Phosphate
HILGINDI_02645 5.2e-154 pstC P probably responsible for the translocation of the substrate across the membrane
HILGINDI_02646 2.4e-156 pstA P Phosphate transport system permease
HILGINDI_02647 8.6e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HILGINDI_02648 1.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HILGINDI_02649 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HILGINDI_02650 1.2e-50 yqzD
HILGINDI_02651 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HILGINDI_02652 4.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HILGINDI_02653 4e-07 yqgO
HILGINDI_02654 1.8e-213 nhaC C Na H antiporter
HILGINDI_02655 2.2e-28 yqgQ S Protein conserved in bacteria
HILGINDI_02656 2.2e-179 glcK 2.7.1.2 G Glucokinase
HILGINDI_02657 5.1e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HILGINDI_02658 1e-198 yqgU
HILGINDI_02659 6.9e-50 yqgV S Thiamine-binding protein
HILGINDI_02660 5.4e-20 yqgW S Protein of unknown function (DUF2759)
HILGINDI_02661 8.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HILGINDI_02662 1.5e-36 yqgY S Protein of unknown function (DUF2626)
HILGINDI_02663 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
HILGINDI_02665 5.9e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HILGINDI_02666 7.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HILGINDI_02667 4.1e-186 corA P Mg2 transporter protein
HILGINDI_02668 6.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HILGINDI_02669 1.2e-183 comGB NU COG1459 Type II secretory pathway, component PulF
HILGINDI_02670 8.9e-50 comGC U Required for transformation and DNA binding
HILGINDI_02671 1.8e-72 gspH NU Tfp pilus assembly protein FimT
HILGINDI_02672 2.6e-20 comGE
HILGINDI_02673 3e-66 comGF U Putative Competence protein ComGF
HILGINDI_02674 2.9e-63 S ComG operon protein 7
HILGINDI_02675 2.3e-26 yqzE S YqzE-like protein
HILGINDI_02676 1.3e-54 yqzG S Protein of unknown function (DUF3889)
HILGINDI_02677 1.6e-120 yqxM
HILGINDI_02678 1e-70 sipW 3.4.21.89 U Signal peptidase
HILGINDI_02679 3.3e-141 tasA S Cell division protein FtsN
HILGINDI_02680 7.8e-55 sinR K transcriptional
HILGINDI_02681 5.2e-23 sinI S Anti-repressor SinI
HILGINDI_02682 8.4e-153 yqhG S Bacterial protein YqhG of unknown function
HILGINDI_02683 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HILGINDI_02684 2.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HILGINDI_02685 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HILGINDI_02686 1.5e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HILGINDI_02687 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
HILGINDI_02688 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HILGINDI_02689 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HILGINDI_02690 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
HILGINDI_02691 1.7e-61 yqhP
HILGINDI_02692 8e-174 yqhQ S Protein of unknown function (DUF1385)
HILGINDI_02693 3.7e-88 yqhR S Conserved membrane protein YqhR
HILGINDI_02694 1.1e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HILGINDI_02695 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HILGINDI_02696 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HILGINDI_02697 4.2e-172 spoIIIAA S stage III sporulation protein AA
HILGINDI_02698 1.7e-85 spoIIIAB S Stage III sporulation protein
HILGINDI_02699 7.6e-29 spoIIIAC S stage III sporulation protein AC
HILGINDI_02700 2.5e-41 spoIIIAD S Stage III sporulation protein AD
HILGINDI_02701 1.1e-199 spoIIIAE S stage III sporulation protein AE
HILGINDI_02702 2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HILGINDI_02703 7.7e-118 spoIIIAG S stage III sporulation protein AG
HILGINDI_02704 2.5e-62 spoIIIAH S SpoIIIAH-like protein
HILGINDI_02705 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HILGINDI_02706 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HILGINDI_02707 8.1e-67 yqhY S protein conserved in bacteria
HILGINDI_02708 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HILGINDI_02709 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HILGINDI_02710 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HILGINDI_02711 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HILGINDI_02712 2.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HILGINDI_02713 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HILGINDI_02714 9.6e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HILGINDI_02715 3.9e-78 argR K Regulates arginine biosynthesis genes
HILGINDI_02716 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
HILGINDI_02717 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
HILGINDI_02718 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HILGINDI_02719 5.2e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HILGINDI_02722 3.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HILGINDI_02724 4.4e-112 K Protein of unknown function (DUF1232)
HILGINDI_02725 2.6e-101 ytaF P Probably functions as a manganese efflux pump
HILGINDI_02726 2.5e-17
HILGINDI_02727 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HILGINDI_02728 3.3e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HILGINDI_02729 6.3e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
HILGINDI_02730 7.4e-155 hbdA 1.1.1.157 I Dehydrogenase
HILGINDI_02731 1.2e-205 mmgC I acyl-CoA dehydrogenase
HILGINDI_02732 4.1e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HILGINDI_02733 7.5e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HILGINDI_02734 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HILGINDI_02735 3.2e-34 yqzF S Protein of unknown function (DUF2627)
HILGINDI_02736 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HILGINDI_02737 6.1e-152 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HILGINDI_02738 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HILGINDI_02739 3.7e-207 buk 2.7.2.7 C Belongs to the acetokinase family
HILGINDI_02740 2.7e-266 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HILGINDI_02741 3e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HILGINDI_02742 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HILGINDI_02743 2.4e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HILGINDI_02744 7.7e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HILGINDI_02745 1e-75 yqiW S Belongs to the UPF0403 family
HILGINDI_02746 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
HILGINDI_02747 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
HILGINDI_02748 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HILGINDI_02749 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
HILGINDI_02750 1.4e-95 yqjB S protein conserved in bacteria
HILGINDI_02752 5.5e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HILGINDI_02753 1.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HILGINDI_02754 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HILGINDI_02755 3.5e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HILGINDI_02756 2.4e-25 yqzJ
HILGINDI_02757 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HILGINDI_02758 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HILGINDI_02759 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HILGINDI_02760 1.9e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HILGINDI_02761 1e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HILGINDI_02762 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HILGINDI_02763 8.4e-51 S GlpM protein
HILGINDI_02764 2.6e-163 K LysR substrate binding domain
HILGINDI_02765 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
HILGINDI_02766 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILGINDI_02769 5.9e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HILGINDI_02770 3.5e-129 IQ reductase
HILGINDI_02771 0.0 pksJ Q Polyketide synthase of type I
HILGINDI_02772 0.0 1.1.1.320 Q Polyketide synthase of type I
HILGINDI_02773 0.0 Q Polyketide synthase of type I
HILGINDI_02774 0.0 pksJ Q Polyketide synthase of type I
HILGINDI_02775 0.0 pfaA Q Polyketide synthase of type I
HILGINDI_02776 0.0 Q Polyketide synthase of type I
HILGINDI_02777 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HILGINDI_02778 5.8e-219 eryK 1.14.13.154 C Cytochrome P450
HILGINDI_02779 2.9e-240 pksG 2.3.3.10 I synthase
HILGINDI_02780 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HILGINDI_02781 2.1e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HILGINDI_02782 2.9e-176 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HILGINDI_02783 1.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HILGINDI_02784 1e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HILGINDI_02785 5.9e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HILGINDI_02786 2.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILGINDI_02788 2.1e-186 yueF S transporter activity
HILGINDI_02790 1.2e-58 S YolD-like protein
HILGINDI_02791 7.2e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HILGINDI_02792 3.9e-89 yqjY K acetyltransferase
HILGINDI_02793 3.6e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HILGINDI_02794 4.1e-178 yqkA K GrpB protein
HILGINDI_02795 1.1e-59 yqkB S Belongs to the HesB IscA family
HILGINDI_02796 7.2e-39 yqkC S Protein of unknown function (DUF2552)
HILGINDI_02797 3.3e-177 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HILGINDI_02799 3.3e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HILGINDI_02801 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HILGINDI_02802 2.8e-221 yqxK 3.6.4.12 L DNA helicase
HILGINDI_02803 7.8e-58 ansR K Transcriptional regulator
HILGINDI_02804 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
HILGINDI_02805 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HILGINDI_02806 2.7e-239 mleN C Na H antiporter
HILGINDI_02807 2.2e-243 mleA 1.1.1.38 C malic enzyme
HILGINDI_02808 5.7e-22
HILGINDI_02809 1.4e-27 yqkK
HILGINDI_02810 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HILGINDI_02811 1.9e-80 fur P Belongs to the Fur family
HILGINDI_02812 6.4e-37 S Protein of unknown function (DUF4227)
HILGINDI_02813 1.7e-165 xerD L recombinase XerD
HILGINDI_02814 4e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HILGINDI_02815 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HILGINDI_02816 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HILGINDI_02817 1.7e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HILGINDI_02818 3.9e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HILGINDI_02819 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILGINDI_02820 3.7e-111 spoVAA S Stage V sporulation protein AA
HILGINDI_02821 3.9e-60 spoVAB S Stage V sporulation protein AB
HILGINDI_02822 2.1e-79 spoVAC S stage V sporulation protein AC
HILGINDI_02823 5e-190 spoVAD I Stage V sporulation protein AD
HILGINDI_02824 3.8e-57 spoVAEB S stage V sporulation protein
HILGINDI_02825 8.8e-110 spoVAEA S stage V sporulation protein
HILGINDI_02826 1.4e-270 spoVAF EG Stage V sporulation protein AF
HILGINDI_02827 3.3e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HILGINDI_02828 9.2e-156 ypuA S Secreted protein
HILGINDI_02829 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HILGINDI_02830 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
HILGINDI_02831 4.5e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HILGINDI_02832 1.7e-49 ypuD
HILGINDI_02833 4.7e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HILGINDI_02834 1e-111 ribE 2.5.1.9 H Riboflavin synthase
HILGINDI_02835 5.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HILGINDI_02836 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HILGINDI_02837 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILGINDI_02838 6.4e-93 ypuF S Domain of unknown function (DUF309)
HILGINDI_02840 1.1e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HILGINDI_02841 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HILGINDI_02842 1.3e-93 ypuI S Protein of unknown function (DUF3907)
HILGINDI_02843 5e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HILGINDI_02844 2e-103 spmA S Spore maturation protein
HILGINDI_02845 1.3e-88 spmB S Spore maturation protein
HILGINDI_02846 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HILGINDI_02847 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HILGINDI_02848 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HILGINDI_02849 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HILGINDI_02850 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_02851 0.0 resE 2.7.13.3 T Histidine kinase
HILGINDI_02852 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HILGINDI_02853 3.7e-199 rsiX
HILGINDI_02854 2.8e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HILGINDI_02855 1.4e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HILGINDI_02856 1.1e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
HILGINDI_02857 2.5e-177 yuaG 3.4.21.72 S protein conserved in bacteria
HILGINDI_02858 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HILGINDI_02859 1.9e-83 yuaE S DinB superfamily
HILGINDI_02860 2.5e-109 yuaD S MOSC domain
HILGINDI_02861 1.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
HILGINDI_02862 1.2e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HILGINDI_02863 1e-96 yuaC K Belongs to the GbsR family
HILGINDI_02864 2.1e-94 yuaB
HILGINDI_02865 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
HILGINDI_02866 2.5e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HILGINDI_02867 2.9e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HILGINDI_02868 6.6e-124 G Cupin
HILGINDI_02869 3.1e-53 yjcN
HILGINDI_02872 2.6e-131 S Aspartate phosphatase response regulator
HILGINDI_02873 3.6e-15
HILGINDI_02874 2.3e-39
HILGINDI_02876 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HILGINDI_02877 9e-196 yubA S transporter activity
HILGINDI_02878 1.4e-184 ygjR S Oxidoreductase
HILGINDI_02879 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HILGINDI_02880 1.6e-237 mcpA NT chemotaxis protein
HILGINDI_02881 3.5e-224 mcpA NT chemotaxis protein
HILGINDI_02882 2.3e-239 mcpA NT chemotaxis protein
HILGINDI_02883 4.5e-219 mcpA NT chemotaxis protein
HILGINDI_02884 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HILGINDI_02885 4.8e-41
HILGINDI_02886 3.3e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HILGINDI_02887 3.1e-77 yugU S Uncharacterised protein family UPF0047
HILGINDI_02888 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HILGINDI_02889 3.9e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HILGINDI_02890 8.3e-117 yugP S Zn-dependent protease
HILGINDI_02891 4.5e-18
HILGINDI_02892 6.7e-27 mstX S Membrane-integrating protein Mistic
HILGINDI_02893 1.1e-181 yugO P COG1226 Kef-type K transport systems
HILGINDI_02894 1.3e-72 yugN S YugN-like family
HILGINDI_02896 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
HILGINDI_02897 6.1e-97 S NADPH-dependent FMN reductase
HILGINDI_02898 2.7e-117 ycaC Q Isochorismatase family
HILGINDI_02899 1.1e-228 yugK C Dehydrogenase
HILGINDI_02900 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HILGINDI_02901 1.8e-34 yuzA S Domain of unknown function (DUF378)
HILGINDI_02902 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HILGINDI_02903 5e-210 yugH 2.6.1.1 E Aminotransferase
HILGINDI_02904 9.9e-83 alaR K Transcriptional regulator
HILGINDI_02905 1.1e-155 yugF I Hydrolase
HILGINDI_02906 1.4e-40 yugE S Domain of unknown function (DUF1871)
HILGINDI_02907 1.6e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HILGINDI_02908 1.2e-230 T PhoQ Sensor
HILGINDI_02909 6.9e-68 kapB G Kinase associated protein B
HILGINDI_02910 4.5e-118 kapD L the KinA pathway to sporulation
HILGINDI_02911 1.5e-185 yuxJ EGP Major facilitator Superfamily
HILGINDI_02912 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HILGINDI_02913 2.2e-72 yuxK S protein conserved in bacteria
HILGINDI_02914 9.3e-74 yufK S Family of unknown function (DUF5366)
HILGINDI_02915 1.5e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HILGINDI_02916 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
HILGINDI_02917 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HILGINDI_02918 2.9e-287 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HILGINDI_02919 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HILGINDI_02920 3.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HILGINDI_02921 3.1e-12
HILGINDI_02922 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HILGINDI_02923 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILGINDI_02924 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILGINDI_02925 1.9e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILGINDI_02926 9.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILGINDI_02927 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILGINDI_02928 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HILGINDI_02929 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HILGINDI_02930 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILGINDI_02931 1e-254 comP 2.7.13.3 T Histidine kinase
HILGINDI_02933 2e-62 comQ H Polyprenyl synthetase
HILGINDI_02935 2.3e-51 yuzC
HILGINDI_02936 7e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HILGINDI_02937 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HILGINDI_02938 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
HILGINDI_02939 7.2e-68 yueI S Protein of unknown function (DUF1694)
HILGINDI_02940 2.8e-38 yueH S YueH-like protein
HILGINDI_02941 6.4e-34 yueG S Spore germination protein gerPA/gerPF
HILGINDI_02942 2.5e-187 yueF S transporter activity
HILGINDI_02943 1.6e-22 S Protein of unknown function (DUF2642)
HILGINDI_02944 3.7e-96 yueE S phosphohydrolase
HILGINDI_02945 4.6e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_02946 6.9e-78 yueC S Family of unknown function (DUF5383)
HILGINDI_02947 0.0 esaA S type VII secretion protein EsaA
HILGINDI_02948 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HILGINDI_02949 2.8e-206 essB S WXG100 protein secretion system (Wss), protein YukC
HILGINDI_02950 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
HILGINDI_02951 3.3e-46 esxA S Belongs to the WXG100 family
HILGINDI_02952 1.5e-228 yukF QT Transcriptional regulator
HILGINDI_02953 6.7e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HILGINDI_02954 8.3e-133 yukJ S Uncharacterized conserved protein (DUF2278)
HILGINDI_02955 1.3e-34 mbtH S MbtH-like protein
HILGINDI_02956 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_02957 3.5e-174 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HILGINDI_02958 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HILGINDI_02959 3.1e-223 entC 5.4.4.2 HQ Isochorismate synthase
HILGINDI_02960 4.6e-135 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HILGINDI_02961 5.6e-166 besA S Putative esterase
HILGINDI_02962 4.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
HILGINDI_02963 1.5e-101 bioY S Biotin biosynthesis protein
HILGINDI_02964 4e-208 yuiF S antiporter
HILGINDI_02965 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HILGINDI_02966 5.9e-77 yuiD S protein conserved in bacteria
HILGINDI_02967 1.2e-117 yuiC S protein conserved in bacteria
HILGINDI_02968 9.9e-28 yuiB S Putative membrane protein
HILGINDI_02969 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
HILGINDI_02970 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HILGINDI_02972 1.2e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HILGINDI_02973 4.8e-29
HILGINDI_02974 3.7e-72 CP Membrane
HILGINDI_02975 3.3e-124 V ABC transporter
HILGINDI_02977 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
HILGINDI_02979 3.3e-92 rimJ 2.3.1.128 J Alanine acetyltransferase
HILGINDI_02980 9.6e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HILGINDI_02981 1.1e-62 erpA S Belongs to the HesB IscA family
HILGINDI_02982 1.6e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HILGINDI_02983 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HILGINDI_02984 2.4e-39 yuzB S Belongs to the UPF0349 family
HILGINDI_02985 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
HILGINDI_02986 6.7e-56 yuzD S protein conserved in bacteria
HILGINDI_02987 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HILGINDI_02988 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HILGINDI_02989 8.9e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HILGINDI_02990 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HILGINDI_02991 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
HILGINDI_02992 4.2e-197 yutH S Spore coat protein
HILGINDI_02993 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HILGINDI_02994 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HILGINDI_02995 1.9e-74 yutE S Protein of unknown function DUF86
HILGINDI_02996 1.7e-47 yutD S protein conserved in bacteria
HILGINDI_02997 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HILGINDI_02998 5.4e-194 lytH M Peptidase, M23
HILGINDI_02999 9.6e-130 yunB S Sporulation protein YunB (Spo_YunB)
HILGINDI_03000 1.8e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HILGINDI_03001 1.8e-145 yunE S membrane transporter protein
HILGINDI_03002 2.6e-168 yunF S Protein of unknown function DUF72
HILGINDI_03003 5.2e-62 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
HILGINDI_03004 2.6e-263 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HILGINDI_03005 4.7e-304 pucR QT COG2508 Regulator of polyketide synthase expression
HILGINDI_03007 3.8e-213 blt EGP Major facilitator Superfamily
HILGINDI_03008 7.9e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HILGINDI_03009 4.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HILGINDI_03010 4.1e-169 bsn L Ribonuclease
HILGINDI_03011 1.1e-206 msmX P Belongs to the ABC transporter superfamily
HILGINDI_03012 3.6e-134 yurK K UTRA
HILGINDI_03013 2e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HILGINDI_03014 6.9e-164 yurM P COG0395 ABC-type sugar transport system, permease component
HILGINDI_03015 2.2e-157 yurN G Binding-protein-dependent transport system inner membrane component
HILGINDI_03016 8.9e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HILGINDI_03017 5.1e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HILGINDI_03018 1.3e-165 K helix_turn_helix, mercury resistance
HILGINDI_03019 4e-14
HILGINDI_03020 3.4e-76
HILGINDI_03021 2.7e-22 S Sporulation delaying protein SdpA
HILGINDI_03023 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HILGINDI_03024 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HILGINDI_03025 9.5e-34
HILGINDI_03026 2.1e-24
HILGINDI_03027 1.4e-78 yncE S Protein of unknown function (DUF2691)
HILGINDI_03028 1.2e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HILGINDI_03029 3e-270 sufB O FeS cluster assembly
HILGINDI_03030 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HILGINDI_03031 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HILGINDI_03032 1.6e-244 sufD O assembly protein SufD
HILGINDI_03033 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HILGINDI_03034 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HILGINDI_03035 8.7e-145 metQ P Belongs to the NlpA lipoprotein family
HILGINDI_03036 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HILGINDI_03037 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HILGINDI_03038 5e-57 yusD S SCP-2 sterol transfer family
HILGINDI_03039 1.6e-54 yusE CO Thioredoxin
HILGINDI_03040 3.7e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HILGINDI_03041 3.7e-40 yusG S Protein of unknown function (DUF2553)
HILGINDI_03042 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HILGINDI_03043 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HILGINDI_03044 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HILGINDI_03045 1.6e-216 fadA 2.3.1.16 I Belongs to the thiolase family
HILGINDI_03046 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HILGINDI_03047 1.1e-164 fadM E Proline dehydrogenase
HILGINDI_03048 3.9e-43
HILGINDI_03049 1.1e-53 yusN M Coat F domain
HILGINDI_03050 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
HILGINDI_03051 8.1e-288 yusP P Major facilitator superfamily
HILGINDI_03052 2e-158 ywbI2 K Transcriptional regulator
HILGINDI_03053 7.7e-140 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HILGINDI_03054 3.9e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HILGINDI_03055 3.3e-39 yusU S Protein of unknown function (DUF2573)
HILGINDI_03056 1.4e-150 yusV 3.6.3.34 HP ABC transporter
HILGINDI_03057 7.2e-45 S YusW-like protein
HILGINDI_03058 0.0 pepF2 E COG1164 Oligoendopeptidase F
HILGINDI_03059 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HILGINDI_03060 3.6e-79 dps P Belongs to the Dps family
HILGINDI_03061 5.4e-240 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HILGINDI_03062 7.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_03063 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
HILGINDI_03064 3.4e-24
HILGINDI_03065 5e-157 yuxN K Transcriptional regulator
HILGINDI_03066 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HILGINDI_03067 6.6e-24 S Protein of unknown function (DUF3970)
HILGINDI_03068 3.8e-260 gerAA EG Spore germination protein
HILGINDI_03069 1.5e-187 gerAB E Spore germination protein
HILGINDI_03070 6.2e-210 gerAC S Spore germination B3/ GerAC like, C-terminal
HILGINDI_03071 1.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILGINDI_03072 5.1e-193 vraS 2.7.13.3 T Histidine kinase
HILGINDI_03073 2.4e-125 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HILGINDI_03074 1.6e-128 liaG S Putative adhesin
HILGINDI_03075 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HILGINDI_03076 8.1e-45 liaI S membrane
HILGINDI_03077 6.1e-230 yvqJ EGP Major facilitator Superfamily
HILGINDI_03078 2.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
HILGINDI_03079 6.3e-224 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HILGINDI_03080 3.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_03081 1.1e-167 yvrC P ABC transporter substrate-binding protein
HILGINDI_03082 9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HILGINDI_03083 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HILGINDI_03084 0.0 T PhoQ Sensor
HILGINDI_03085 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_03086 1.1e-36
HILGINDI_03087 1.7e-102 yvrI K RNA polymerase
HILGINDI_03088 1.6e-15 S YvrJ protein family
HILGINDI_03089 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
HILGINDI_03090 8.4e-67 yvrL S Regulatory protein YrvL
HILGINDI_03091 5.4e-147 fhuC 3.6.3.34 HP ABC transporter
HILGINDI_03092 4e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_03093 5.6e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_03094 4e-178 fhuD P ABC transporter
HILGINDI_03095 2e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HILGINDI_03096 2.9e-236 yvsH E Arginine ornithine antiporter
HILGINDI_03097 3.6e-14 S Small spore protein J (Spore_SspJ)
HILGINDI_03098 3.9e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HILGINDI_03099 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HILGINDI_03100 2.7e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HILGINDI_03101 1.4e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HILGINDI_03102 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
HILGINDI_03103 1.1e-113 yfiK K Regulator
HILGINDI_03104 1.3e-180 T Histidine kinase
HILGINDI_03105 5.6e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HILGINDI_03106 1.4e-193 yfiM V ABC-2 type transporter
HILGINDI_03107 1.4e-201 yfiN V COG0842 ABC-type multidrug transport system, permease component
HILGINDI_03108 5e-156 yvgN S reductase
HILGINDI_03109 1.1e-86 yvgO
HILGINDI_03110 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HILGINDI_03111 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HILGINDI_03112 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HILGINDI_03113 0.0 helD 3.6.4.12 L DNA helicase
HILGINDI_03114 3.1e-99 yvgT S membrane
HILGINDI_03115 2.6e-141 S Metallo-peptidase family M12
HILGINDI_03116 6e-73 bdbC O Required for disulfide bond formation in some proteins
HILGINDI_03117 8.3e-101 bdbD O Thioredoxin
HILGINDI_03118 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HILGINDI_03119 0.0 copA 3.6.3.54 P P-type ATPase
HILGINDI_03120 2.6e-29 copZ P Heavy-metal-associated domain
HILGINDI_03121 3.7e-48 csoR S transcriptional
HILGINDI_03122 4e-195 yvaA 1.1.1.371 S Oxidoreductase
HILGINDI_03123 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HILGINDI_03124 1.7e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILGINDI_03125 1.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
HILGINDI_03126 2.4e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILGINDI_03127 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HILGINDI_03128 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HILGINDI_03129 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
HILGINDI_03130 9.9e-149 tcyK M Bacterial periplasmic substrate-binding proteins
HILGINDI_03131 4.6e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
HILGINDI_03132 3e-101 ytmI K Acetyltransferase (GNAT) domain
HILGINDI_03133 1.4e-164 ytlI K LysR substrate binding domain
HILGINDI_03134 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HILGINDI_03135 6.3e-48 yrdF K ribonuclease inhibitor
HILGINDI_03137 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HILGINDI_03138 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HILGINDI_03139 7.4e-143 est 3.1.1.1 S Carboxylesterase
HILGINDI_03140 4.8e-24 secG U Preprotein translocase subunit SecG
HILGINDI_03141 6e-35 yvzC K Transcriptional
HILGINDI_03142 7.4e-68 K transcriptional
HILGINDI_03143 4e-72 yvaO K Cro/C1-type HTH DNA-binding domain
HILGINDI_03144 8.8e-53 yodB K transcriptional
HILGINDI_03145 4.1e-259 T His Kinase A (phosphoacceptor) domain
HILGINDI_03146 2e-123 K Transcriptional regulatory protein, C terminal
HILGINDI_03147 7.5e-138 mutG S ABC-2 family transporter protein
HILGINDI_03148 8.4e-123 spaE S ABC-2 family transporter protein
HILGINDI_03149 2.5e-127 mutF V ABC transporter, ATP-binding protein
HILGINDI_03150 2.3e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HILGINDI_03151 1.4e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HILGINDI_03152 7e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HILGINDI_03153 3.7e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HILGINDI_03154 4.3e-76 yvbF K Belongs to the GbsR family
HILGINDI_03155 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HILGINDI_03156 7.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HILGINDI_03157 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HILGINDI_03158 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HILGINDI_03159 1.9e-98 yvbF K Belongs to the GbsR family
HILGINDI_03160 5.2e-105 yvbG U UPF0056 membrane protein
HILGINDI_03161 1.4e-114 exoY M Membrane
HILGINDI_03162 0.0 tcaA S response to antibiotic
HILGINDI_03163 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
HILGINDI_03164 2.5e-212 EGP Major facilitator Superfamily
HILGINDI_03165 1e-178
HILGINDI_03166 9.8e-126 S GlcNAc-PI de-N-acetylase
HILGINDI_03167 2.1e-142 C WbqC-like protein family
HILGINDI_03168 3.4e-150 M Protein involved in cellulose biosynthesis
HILGINDI_03169 5.5e-239 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HILGINDI_03170 1.2e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
HILGINDI_03171 1.1e-217 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HILGINDI_03172 6.2e-257 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HILGINDI_03173 8e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HILGINDI_03174 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HILGINDI_03175 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HILGINDI_03176 1.5e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HILGINDI_03177 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HILGINDI_03178 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HILGINDI_03179 6.8e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HILGINDI_03181 9.6e-253 araE EGP Major facilitator Superfamily
HILGINDI_03182 2.9e-204 araR K transcriptional
HILGINDI_03183 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILGINDI_03184 1.1e-124 yvbU K Transcriptional regulator
HILGINDI_03185 1.5e-156 yvbV EG EamA-like transporter family
HILGINDI_03186 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HILGINDI_03187 5.3e-261
HILGINDI_03188 1.1e-183 purR7 5.1.1.1 K Transcriptional regulator
HILGINDI_03189 7.7e-115 yyaS S Membrane
HILGINDI_03190 6.7e-167 3.1.3.104 S hydrolases of the HAD superfamily
HILGINDI_03191 3.5e-152 ybbH_1 K RpiR family transcriptional regulator
HILGINDI_03192 1.2e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
HILGINDI_03193 8.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
HILGINDI_03196 3.9e-25 M nucleic acid phosphodiester bond hydrolysis
HILGINDI_03197 1.8e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HILGINDI_03198 2.1e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HILGINDI_03199 3.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HILGINDI_03200 1.7e-218 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILGINDI_03201 1.3e-120 yvfI K COG2186 Transcriptional regulators
HILGINDI_03202 8.4e-304 yvfH C L-lactate permease
HILGINDI_03203 2.6e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HILGINDI_03204 2.7e-32 yvfG S YvfG protein
HILGINDI_03205 1.4e-189 yvfF GM Exopolysaccharide biosynthesis protein
HILGINDI_03206 5.3e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HILGINDI_03207 2.7e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HILGINDI_03208 9.8e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HILGINDI_03209 1.4e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HILGINDI_03210 4.4e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HILGINDI_03211 1.7e-204 epsI GM pyruvyl transferase
HILGINDI_03212 2e-194 epsH GT2 S Glycosyltransferase like family 2
HILGINDI_03213 3.5e-205 epsG S EpsG family
HILGINDI_03214 2.1e-213 epsF GT4 M Glycosyl transferases group 1
HILGINDI_03215 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HILGINDI_03216 1.1e-217 epsD GT4 M Glycosyl transferase 4-like
HILGINDI_03217 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HILGINDI_03218 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HILGINDI_03219 8.4e-120 ywqC M biosynthesis protein
HILGINDI_03220 1.9e-77 slr K transcriptional
HILGINDI_03221 1.1e-275 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HILGINDI_03223 8.3e-96 ywjB H RibD C-terminal domain
HILGINDI_03224 2.8e-111 yyaS S Membrane
HILGINDI_03225 8.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILGINDI_03226 1.6e-93 padC Q Phenolic acid decarboxylase
HILGINDI_03227 1.2e-12 MA20_18690 S Protein of unknown function (DUF3237)
HILGINDI_03228 6.3e-13 S Protein of unknown function (DUF1433)
HILGINDI_03229 7.5e-20 S Protein of unknown function (DUF1433)
HILGINDI_03230 7.1e-25 S Protein of unknown function (DUF1433)
HILGINDI_03231 6.6e-241 I Pfam Lipase (class 3)
HILGINDI_03232 3.1e-34
HILGINDI_03234 1.5e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HILGINDI_03235 1.2e-219 rafB P LacY proton/sugar symporter
HILGINDI_03236 1.6e-182 scrR K transcriptional
HILGINDI_03237 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HILGINDI_03238 1.3e-162 yraN K Transcriptional regulator
HILGINDI_03239 2.1e-213 yraM S PrpF protein
HILGINDI_03240 4e-251 EGP Sugar (and other) transporter
HILGINDI_03241 2.1e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HILGINDI_03242 4.4e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HILGINDI_03243 4.7e-280 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HILGINDI_03244 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HILGINDI_03245 7.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HILGINDI_03246 1.6e-79 M Ribonuclease
HILGINDI_03247 1.3e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HILGINDI_03248 4.7e-36 crh G Phosphocarrier protein Chr
HILGINDI_03249 3.1e-170 whiA K May be required for sporulation
HILGINDI_03250 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HILGINDI_03251 1.1e-166 rapZ S Displays ATPase and GTPase activities
HILGINDI_03252 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HILGINDI_03253 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HILGINDI_03254 2.1e-122 usp CBM50 M protein conserved in bacteria
HILGINDI_03255 2.9e-276 S COG0457 FOG TPR repeat
HILGINDI_03256 7.2e-192 sasA T Histidine kinase
HILGINDI_03257 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_03258 1e-57
HILGINDI_03259 0.0 msbA2 3.6.3.44 V ABC transporter
HILGINDI_03260 3.7e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HILGINDI_03261 3.1e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HILGINDI_03262 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HILGINDI_03263 9.6e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HILGINDI_03264 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HILGINDI_03265 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HILGINDI_03266 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HILGINDI_03267 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HILGINDI_03268 1.8e-138 yvpB NU protein conserved in bacteria
HILGINDI_03269 5.4e-84 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HILGINDI_03270 4.8e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HILGINDI_03271 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HILGINDI_03272 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HILGINDI_03273 1.5e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HILGINDI_03274 1.2e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HILGINDI_03275 1.2e-132 yvoA K transcriptional
HILGINDI_03276 6.2e-105 yxaF K Transcriptional regulator
HILGINDI_03277 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HILGINDI_03278 3.9e-41 yvlD S Membrane
HILGINDI_03279 1.3e-25 pspB KT PspC domain
HILGINDI_03280 3.2e-166 yvlB S Putative adhesin
HILGINDI_03281 6.1e-49 yvlA
HILGINDI_03282 3e-38 yvkN
HILGINDI_03283 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HILGINDI_03284 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HILGINDI_03285 7.6e-33 csbA S protein conserved in bacteria
HILGINDI_03286 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HILGINDI_03287 2.4e-110 yvkB K Transcriptional regulator
HILGINDI_03288 3e-227 yvkA EGP Major facilitator Superfamily
HILGINDI_03289 1e-26 bacT Q Thioesterase domain
HILGINDI_03291 5.1e-177 S Psort location CytoplasmicMembrane, score
HILGINDI_03292 2.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HILGINDI_03293 3.4e-55 swrA S Swarming motility protein
HILGINDI_03294 4.6e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HILGINDI_03295 4.1e-227 ywoF P Right handed beta helix region
HILGINDI_03296 2.7e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HILGINDI_03297 1e-122 ftsE D cell division ATP-binding protein FtsE
HILGINDI_03298 6.2e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
HILGINDI_03299 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HILGINDI_03300 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HILGINDI_03301 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HILGINDI_03302 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HILGINDI_03303 6.8e-68
HILGINDI_03304 2.6e-10 fliT S bacterial-type flagellum organization
HILGINDI_03305 3e-66 fliS N flagellar protein FliS
HILGINDI_03306 5.2e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HILGINDI_03307 4.2e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HILGINDI_03308 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HILGINDI_03309 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HILGINDI_03310 1.1e-74 yviE
HILGINDI_03311 6.1e-163 flgL N Belongs to the bacterial flagellin family
HILGINDI_03312 1.8e-273 flgK N flagellar hook-associated protein
HILGINDI_03313 8.9e-81 flgN NOU FlgN protein
HILGINDI_03314 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
HILGINDI_03315 2.4e-74 yvyF S flagellar protein
HILGINDI_03316 1.6e-77 comFC S Phosphoribosyl transferase domain
HILGINDI_03317 1.5e-43 comFB S Late competence development protein ComFB
HILGINDI_03318 6.8e-259 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HILGINDI_03319 5.5e-158 degV S protein conserved in bacteria
HILGINDI_03320 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILGINDI_03321 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HILGINDI_03322 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HILGINDI_03323 3e-173 yvhJ K Transcriptional regulator
HILGINDI_03324 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HILGINDI_03325 8e-240 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HILGINDI_03326 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
HILGINDI_03327 1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
HILGINDI_03328 1.1e-256 tuaE M Teichuronic acid biosynthesis protein
HILGINDI_03329 2.5e-250 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HILGINDI_03330 2.9e-221 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HILGINDI_03331 8.7e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HILGINDI_03332 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HILGINDI_03333 5.4e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HILGINDI_03334 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HILGINDI_03335 5.9e-49
HILGINDI_03336 8.5e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HILGINDI_03337 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HILGINDI_03338 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HILGINDI_03339 8.1e-38 yaaB S Domain of unknown function (DUF370)
HILGINDI_03340 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HILGINDI_03341 6.9e-33 yaaA S S4 domain
HILGINDI_03342 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HILGINDI_03343 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HILGINDI_03344 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HILGINDI_03345 9.5e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HILGINDI_03346 1.4e-110 jag S single-stranded nucleic acid binding R3H
HILGINDI_03347 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HILGINDI_03348 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HILGINDI_03349 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HILGINDI_03350 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HILGINDI_03351 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
HILGINDI_03352 7.9e-149 spo0J K Belongs to the ParB family
HILGINDI_03353 1.5e-109 yyaC S Sporulation protein YyaC
HILGINDI_03354 1.1e-30 4.2.1.103 K FR47-like protein
HILGINDI_03355 3.1e-176 yyaD S Membrane
HILGINDI_03356 2.3e-33 yyzM S protein conserved in bacteria
HILGINDI_03357 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HILGINDI_03358 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HILGINDI_03359 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HILGINDI_03360 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HILGINDI_03361 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HILGINDI_03362 3.9e-107 adaA 3.2.2.21 K Transcriptional regulator
HILGINDI_03363 1.8e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HILGINDI_03364 3.1e-144 xth 3.1.11.2 L exodeoxyribonuclease III
HILGINDI_03365 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HILGINDI_03366 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILGINDI_03367 6.2e-249 ydjK G Sugar (and other) transporter
HILGINDI_03368 4.1e-164 yyaK S CAAX protease self-immunity
HILGINDI_03369 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HILGINDI_03370 6.7e-130 ydfC EG EamA-like transporter family
HILGINDI_03371 1.4e-249 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILGINDI_03372 5.4e-41 qacC U Small Multidrug Resistance protein
HILGINDI_03373 1.7e-96
HILGINDI_03374 5.8e-141 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HILGINDI_03375 1.7e-165 K Transcriptional regulator
HILGINDI_03376 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
HILGINDI_03377 6.8e-164 eaeH M Domain of Unknown Function (DUF1259)
HILGINDI_03378 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
HILGINDI_03379 2.5e-77 yybA 2.3.1.57 K transcriptional
HILGINDI_03380 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HILGINDI_03381 3.5e-68 ydgJ K Winged helix DNA-binding domain
HILGINDI_03382 5.6e-115 drgA C nitroreductase
HILGINDI_03383 1.3e-55 ypaA S Protein of unknown function (DUF1304)
HILGINDI_03384 1.8e-164 gltC K Transcriptional regulator
HILGINDI_03385 2.8e-216 ynfM EGP Major facilitator Superfamily
HILGINDI_03386 1.1e-100 E LysE type translocator
HILGINDI_03387 9.9e-163 yfiE K LysR substrate binding domain
HILGINDI_03388 3.7e-77 H porphobilinogen synthase activity
HILGINDI_03389 1.1e-77 eamA1 EG spore germination
HILGINDI_03390 1.3e-243 trpE 2.6.1.85, 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HILGINDI_03391 1.9e-14 comA K response regulator
HILGINDI_03392 2e-161 G Major Facilitator Superfamily
HILGINDI_03393 5.4e-76 dinB S PFAM DinB family protein
HILGINDI_03394 1.8e-116 K FCD domain
HILGINDI_03395 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HILGINDI_03396 2.2e-273 sacB 2.4.1.10 GH68 M levansucrase activity
HILGINDI_03397 2.8e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HILGINDI_03398 5e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HILGINDI_03399 2.8e-66 ydeP3 K Transcriptional regulator
HILGINDI_03400 6.5e-85 cotF M Spore coat protein
HILGINDI_03402 1.6e-158 yybS S membrane
HILGINDI_03403 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HILGINDI_03404 4.9e-73 rplI J binds to the 23S rRNA
HILGINDI_03405 7.2e-90 KLT COG0515 Serine threonine protein kinase
HILGINDI_03406 2.7e-120 S GlcNAc-PI de-N-acetylase
HILGINDI_03407 1.3e-235 M Glycosyltransferase Family 4
HILGINDI_03408 9.1e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
HILGINDI_03409 1.9e-205 S Ecdysteroid kinase
HILGINDI_03410 2.7e-241 M Glycosyltransferase Family 4
HILGINDI_03411 3.5e-17 yycC K YycC-like protein
HILGINDI_03413 8e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HILGINDI_03414 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HILGINDI_03415 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILGINDI_03416 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HILGINDI_03421 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_03422 0.0 vicK 2.7.13.3 T Histidine kinase
HILGINDI_03423 1.2e-260 yycH S protein conserved in bacteria
HILGINDI_03424 4.4e-152 yycI S protein conserved in bacteria
HILGINDI_03425 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HILGINDI_03426 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HILGINDI_03427 1.6e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_03428 1.7e-252 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HILGINDI_03429 7.6e-191 2.7.7.73, 2.7.7.80 H ThiF family
HILGINDI_03430 1.4e-261
HILGINDI_03431 3.4e-198 S Major Facilitator Superfamily
HILGINDI_03432 8.8e-306 S ABC transporter
HILGINDI_03433 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
HILGINDI_03434 3.4e-261 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HILGINDI_03435 2.2e-42 sdpR K transcriptional
HILGINDI_03436 1.4e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HILGINDI_03437 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HILGINDI_03438 2.6e-258 rocE E amino acid
HILGINDI_03439 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HILGINDI_03440 5.8e-200 S Histidine kinase
HILGINDI_03442 3.7e-87 yycN 2.3.1.128 K Acetyltransferase
HILGINDI_03443 5.1e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
HILGINDI_03444 1.4e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HILGINDI_03445 1.1e-217 yycP
HILGINDI_03447 7.9e-08 S YyzF-like protein
HILGINDI_03448 5.7e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HILGINDI_03449 1.2e-33
HILGINDI_03450 0.0 L AAA domain
HILGINDI_03452 9.4e-18
HILGINDI_03453 1.1e-178 S Fusaric acid resistance protein-like
HILGINDI_03454 4.6e-188 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HILGINDI_03455 2.7e-90 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HILGINDI_03456 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HILGINDI_03457 1e-156 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HILGINDI_03458 1.1e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HILGINDI_03459 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HILGINDI_03460 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HILGINDI_03461 1e-229 XK27_00240 S Fic/DOC family
HILGINDI_03462 2.3e-287 ahpF O Alkyl hydroperoxide reductase
HILGINDI_03463 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HILGINDI_03464 5.6e-92 mrr V Mrr N-terminal domain
HILGINDI_03465 4.6e-22 3.4.24.84 O metalloendopeptidase activity
HILGINDI_03466 6.2e-128 E Ring-cleavage extradiol dioxygenase
HILGINDI_03467 1.5e-74 yxaI S membrane protein domain
HILGINDI_03468 3.4e-203 EGP Major facilitator Superfamily
HILGINDI_03469 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
HILGINDI_03470 3e-64 S Family of unknown function (DUF5391)
HILGINDI_03471 1.8e-141 S PQQ-like domain
HILGINDI_03472 3.4e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HILGINDI_03473 2e-219 yxbF K Bacterial regulatory proteins, tetR family
HILGINDI_03474 2.2e-201 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HILGINDI_03475 1.7e-199 desK 2.7.13.3 T Histidine kinase
HILGINDI_03476 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILGINDI_03477 2.1e-151 IQ Enoyl-(Acyl carrier protein) reductase
HILGINDI_03479 0.0 htpG O Molecular chaperone. Has ATPase activity
HILGINDI_03480 6.7e-246 csbC EGP Major facilitator Superfamily
HILGINDI_03481 4.9e-176 iolS C Aldo keto reductase
HILGINDI_03482 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
HILGINDI_03483 2.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HILGINDI_03484 1.5e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HILGINDI_03485 5.7e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HILGINDI_03486 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HILGINDI_03487 4.2e-177 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HILGINDI_03488 7.1e-234 iolF EGP Major facilitator Superfamily
HILGINDI_03489 9.5e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HILGINDI_03490 1.1e-166 iolH G Xylose isomerase-like TIM barrel
HILGINDI_03491 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HILGINDI_03492 3.5e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HILGINDI_03493 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILGINDI_03494 3.9e-176 T PhoQ Sensor
HILGINDI_03495 3.9e-81 yxdL V ABC transporter, ATP-binding protein
HILGINDI_03496 6e-35 yxdL V ABC transporter, ATP-binding protein
HILGINDI_03497 0.0 yxdM V ABC transporter (permease)
HILGINDI_03498 7.6e-58 yxeA S Protein of unknown function (DUF1093)
HILGINDI_03499 2.4e-178 fhuD P Periplasmic binding protein
HILGINDI_03500 6e-35
HILGINDI_03501 3.2e-22 yxeD
HILGINDI_03502 6.4e-13 yxeE
HILGINDI_03505 4e-150 yidA S hydrolases of the HAD superfamily
HILGINDI_03506 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HILGINDI_03507 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HILGINDI_03508 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HILGINDI_03509 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HILGINDI_03510 8.3e-252 lysP E amino acid
HILGINDI_03511 3.8e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HILGINDI_03512 5.5e-239 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HILGINDI_03513 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HILGINDI_03514 2.5e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
HILGINDI_03515 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HILGINDI_03516 4.8e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HILGINDI_03517 1.8e-71 L NgoFVII restriction endonuclease
HILGINDI_03518 1.6e-99 S GTP binding
HILGINDI_03519 1.1e-182 2.1.1.37 H C-5 cytosine-specific DNA methylase
HILGINDI_03520 2e-44 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HILGINDI_03521 1.8e-13 S Domain of unknown function (DUF5082)
HILGINDI_03522 1.5e-24 yxiC S Family of unknown function (DUF5344)
HILGINDI_03523 1.2e-177 S nuclease activity
HILGINDI_03524 7.8e-25
HILGINDI_03525 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILGINDI_03526 2.7e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HILGINDI_03527 9.8e-74 yxiE T Belongs to the universal stress protein A family
HILGINDI_03528 3.6e-147 yxxF EG EamA-like transporter family
HILGINDI_03529 1.3e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
HILGINDI_03532 1e-64 yxxG
HILGINDI_03533 2.6e-73 yxiG
HILGINDI_03536 3.1e-31
HILGINDI_03537 1e-78
HILGINDI_03538 3.2e-110
HILGINDI_03539 5.1e-15 S YxiJ-like protein
HILGINDI_03540 2.3e-22
HILGINDI_03542 1.1e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HILGINDI_03543 6.4e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
HILGINDI_03544 7e-150 licT K transcriptional antiterminator
HILGINDI_03545 1.5e-143 exoK GH16 M licheninase activity
HILGINDI_03546 6.2e-222 citH C Citrate transporter
HILGINDI_03547 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HILGINDI_03548 1.4e-50 yxiS
HILGINDI_03549 3e-74 T Domain of unknown function (DUF4163)
HILGINDI_03550 3.8e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HILGINDI_03551 7.6e-163 rlmA 2.1.1.187 Q Methyltransferase domain
HILGINDI_03552 1.4e-217 yxjG 2.1.1.14 E Methionine synthase
HILGINDI_03553 1.8e-86 yxjI S LURP-one-related
HILGINDI_03556 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HILGINDI_03557 5.1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HILGINDI_03558 3.8e-87 yxkC S Domain of unknown function (DUF4352)
HILGINDI_03559 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HILGINDI_03560 1.5e-166 lrp QT PucR C-terminal helix-turn-helix domain
HILGINDI_03561 1.5e-203 msmK P Belongs to the ABC transporter superfamily
HILGINDI_03562 1.6e-157 yxkH G Polysaccharide deacetylase
HILGINDI_03563 1e-214 cimH C COG3493 Na citrate symporter
HILGINDI_03564 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
HILGINDI_03565 5.5e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HILGINDI_03566 0.0 cydD V ATP-binding
HILGINDI_03567 1.4e-293 cydD V ATP-binding protein
HILGINDI_03568 3.8e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HILGINDI_03569 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HILGINDI_03570 7.2e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HILGINDI_03571 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HILGINDI_03572 4.6e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HILGINDI_03573 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HILGINDI_03574 3.5e-157 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HILGINDI_03575 5.1e-286 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HILGINDI_03576 3.7e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HILGINDI_03577 9.1e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HILGINDI_03578 5.8e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HILGINDI_03579 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HILGINDI_03580 1.4e-59 arsR K transcriptional
HILGINDI_03581 4e-167 cbrA3 P Periplasmic binding protein
HILGINDI_03582 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_03583 1.6e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILGINDI_03584 6.6e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HILGINDI_03585 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HILGINDI_03586 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HILGINDI_03587 2.2e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HILGINDI_03588 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HILGINDI_03589 4.6e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HILGINDI_03590 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HILGINDI_03591 3.7e-229 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HILGINDI_03592 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_03593 3.7e-229 dltB M membrane protein involved in D-alanine export
HILGINDI_03594 4.2e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILGINDI_03595 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
HILGINDI_03596 8.4e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HILGINDI_03597 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
HILGINDI_03598 1.9e-196 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HILGINDI_03599 1.7e-82 ywaE K Transcriptional regulator
HILGINDI_03600 1.7e-197 aplB S Sodium:solute symporter family
HILGINDI_03601 1.8e-111 1.1.1.1 C Iron-containing alcohol dehydrogenase
HILGINDI_03602 1.4e-87 K Transcriptional regulator
HILGINDI_03603 2.7e-142 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HILGINDI_03604 2.1e-237 hpaE 1.2.1.60 C Belongs to the aldehyde dehydrogenase family
HILGINDI_03605 4.7e-242 hpaB 1.14.14.9 Q 4-hydroxyphenylacetate 3-hydroxylase C terminal
HILGINDI_03606 1.4e-149 hpaD 1.13.11.2 E COG0346 Lactoylglutathione lyase and related lyases
HILGINDI_03607 1.6e-173 gabD C Aldehyde dehydrogenase family
HILGINDI_03608 5e-50 ribF 2.7.1.26, 2.7.7.2 H FAD synthetase
HILGINDI_03609 8.5e-65 hpaG1 4.1.1.68 Q 4-hydroxyphenylacetate degradation bifunctional isomerase decarboxylase
HILGINDI_03610 2.7e-111 hpaG 4.1.1.68 Q 4-hydroxyphenylacetate degradation bifunctional isomerase
HILGINDI_03611 2.5e-41 hpcD 4.1.1.68, 5.3.3.10 E 5-carboxymethyl-2-hydroxymuconate isomerase
HILGINDI_03612 3.5e-101 drgA C nitroreductase
HILGINDI_03613 3.3e-133 E Amino acid permease
HILGINDI_03614 6.2e-212 2.6.1.113 H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HILGINDI_03615 1.6e-210 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HILGINDI_03616 1.5e-130 KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HILGINDI_03617 1.9e-111 ywaF S Integral membrane protein
HILGINDI_03618 3.3e-163 gspA M General stress
HILGINDI_03619 1.9e-266 epr 3.4.21.62 O Belongs to the peptidase S8 family
HILGINDI_03620 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HILGINDI_03621 7.6e-67 ywbC 4.4.1.5 E glyoxalase
HILGINDI_03622 5.5e-225 ywbD 2.1.1.191 J Methyltransferase
HILGINDI_03623 1e-170 yjfC O Predicted Zn-dependent protease (DUF2268)
HILGINDI_03624 1.2e-140 mta K transcriptional
HILGINDI_03625 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HILGINDI_03626 1.5e-110 ywbG M effector of murein hydrolase
HILGINDI_03627 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HILGINDI_03628 8.2e-152 ywbI K Transcriptional regulator
HILGINDI_03629 2.1e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HILGINDI_03630 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HILGINDI_03631 6.1e-189 ywbN P Dyp-type peroxidase family protein
HILGINDI_03632 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HILGINDI_03633 2.6e-134 S Streptomycin biosynthesis protein StrF
HILGINDI_03634 1.9e-129 H Methionine biosynthesis protein MetW
HILGINDI_03636 2.5e-112 ywcC K Bacterial regulatory proteins, tetR family
HILGINDI_03637 3.5e-62 gtcA S GtrA-like protein
HILGINDI_03638 7.7e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HILGINDI_03639 2.6e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HILGINDI_03640 8.4e-27 ywzA S membrane
HILGINDI_03641 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HILGINDI_03642 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HILGINDI_03643 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HILGINDI_03644 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HILGINDI_03645 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HILGINDI_03646 1.4e-79 ysnE K acetyltransferase
HILGINDI_03647 2.8e-208 rodA D Belongs to the SEDS family
HILGINDI_03648 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HILGINDI_03649 4.4e-183 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILGINDI_03650 0.0 vpr O Belongs to the peptidase S8 family
HILGINDI_03652 8.3e-151 sacT K transcriptional antiterminator
HILGINDI_03653 1.5e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILGINDI_03654 5.6e-288 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
HILGINDI_03655 9.7e-20 ywdA
HILGINDI_03656 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HILGINDI_03657 1.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HILGINDI_03658 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HILGINDI_03659 2.3e-40 ywdI S Family of unknown function (DUF5327)
HILGINDI_03660 7.5e-231 ywdJ F Xanthine uracil
HILGINDI_03661 4.2e-46 ywdK S small membrane protein
HILGINDI_03662 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HILGINDI_03663 2.6e-143 spsA M Spore Coat
HILGINDI_03664 5.7e-277 spsB M Capsule polysaccharide biosynthesis protein
HILGINDI_03665 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
HILGINDI_03666 5.5e-158 spsD 2.3.1.210 K Spore Coat
HILGINDI_03667 9.9e-216 spsE 2.5.1.56 M acid synthase
HILGINDI_03668 8.2e-134 spsF M Spore Coat
HILGINDI_03669 4.3e-186 spsG M Spore Coat
HILGINDI_03670 2.7e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HILGINDI_03671 2.7e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HILGINDI_03672 8.1e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HILGINDI_03673 3.5e-87 spsL 5.1.3.13 M Spore Coat
HILGINDI_03674 2.1e-58
HILGINDI_03675 7.3e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HILGINDI_03676 7.8e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HILGINDI_03677 0.0 rocB E arginine degradation protein
HILGINDI_03678 7.5e-261 lysP E amino acid
HILGINDI_03679 9e-207 tcaB EGP Major facilitator Superfamily
HILGINDI_03680 2.4e-223 ywfA EGP Major facilitator Superfamily
HILGINDI_03681 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HILGINDI_03682 4.4e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HILGINDI_03683 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILGINDI_03684 2e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HILGINDI_03685 4.7e-208 bacE EGP Major facilitator Superfamily
HILGINDI_03686 3.5e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HILGINDI_03687 1.4e-139 IQ Enoyl-(Acyl carrier protein) reductase
HILGINDI_03688 1.1e-146 ywfI C May function as heme-dependent peroxidase
HILGINDI_03689 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HILGINDI_03690 4.8e-158 MA20_14895 S Conserved hypothetical protein 698
HILGINDI_03691 5.1e-162 cysL K Transcriptional regulator
HILGINDI_03692 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HILGINDI_03694 8.3e-187
HILGINDI_03697 7.2e-167 yhcI S ABC transporter (permease)
HILGINDI_03698 2.2e-165 V ABC transporter, ATP-binding protein
HILGINDI_03699 8.1e-94 S membrane
HILGINDI_03700 4.8e-51 padR K PadR family transcriptional regulator
HILGINDI_03701 3e-110 rsfA_1
HILGINDI_03702 6.9e-36 ywzC S Belongs to the UPF0741 family
HILGINDI_03703 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HILGINDI_03704 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
HILGINDI_03705 1.3e-246 yhdG_1 E C-terminus of AA_permease
HILGINDI_03706 1.8e-69 ywhA K Transcriptional regulator
HILGINDI_03707 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HILGINDI_03708 1.2e-117 ywhC S Peptidase family M50
HILGINDI_03709 1.4e-95 ywhD S YwhD family
HILGINDI_03710 3.3e-79
HILGINDI_03711 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HILGINDI_03712 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HILGINDI_03713 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
HILGINDI_03716 1.8e-76 CP Membrane
HILGINDI_03718 2.2e-27 S Domain of unknown function (DUF4177)
HILGINDI_03719 6.5e-33
HILGINDI_03720 2.6e-29 ydcG K sequence-specific DNA binding
HILGINDI_03722 3.2e-76 S aspartate phosphatase
HILGINDI_03723 2.4e-200 ywhK CO amine dehydrogenase activity
HILGINDI_03724 1.2e-223 ywhL CO amine dehydrogenase activity
HILGINDI_03726 4.7e-73 ywiB S protein conserved in bacteria
HILGINDI_03727 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HILGINDI_03728 5.8e-214 narK P COG2223 Nitrate nitrite transporter
HILGINDI_03729 1e-128 fnr K helix_turn_helix, cAMP Regulatory protein
HILGINDI_03730 1.7e-139 ywiC S YwiC-like protein
HILGINDI_03731 4.5e-85 arfM T cyclic nucleotide binding
HILGINDI_03732 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HILGINDI_03733 2e-293 narH 1.7.5.1 C Nitrate reductase, beta
HILGINDI_03734 2.1e-97 narJ 1.7.5.1 C nitrate reductase
HILGINDI_03735 4.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HILGINDI_03736 1.5e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HILGINDI_03737 3.7e-301 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HILGINDI_03738 0.0 ywjA V ABC transporter
HILGINDI_03739 4.2e-43 ywjC
HILGINDI_03740 1.5e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HILGINDI_03741 9.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HILGINDI_03742 0.0 fadF C COG0247 Fe-S oxidoreductase
HILGINDI_03743 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HILGINDI_03744 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HILGINDI_03745 1.7e-93 ywjG S Domain of unknown function (DUF2529)
HILGINDI_03746 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
HILGINDI_03747 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HILGINDI_03748 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HILGINDI_03749 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HILGINDI_03750 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HILGINDI_03751 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HILGINDI_03752 1.1e-32 rpmE J Binds the 23S rRNA
HILGINDI_03753 4.1e-104 tdk 2.7.1.21 F thymidine kinase
HILGINDI_03754 0.0 sfcA 1.1.1.38 C malic enzyme
HILGINDI_03755 3.6e-158 ywkB S Membrane transport protein
HILGINDI_03756 1.5e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HILGINDI_03757 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILGINDI_03758 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HILGINDI_03759 5.2e-156 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HILGINDI_03761 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
HILGINDI_03762 2e-118 spoIIR S stage II sporulation protein R
HILGINDI_03763 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HILGINDI_03764 1e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HILGINDI_03765 5.8e-92 mntP P Probably functions as a manganese efflux pump
HILGINDI_03766 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HILGINDI_03767 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HILGINDI_03768 5.9e-97 ywlG S Belongs to the UPF0340 family
HILGINDI_03769 3.5e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HILGINDI_03770 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HILGINDI_03771 2.1e-61 atpI S ATP synthase
HILGINDI_03772 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
HILGINDI_03773 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HILGINDI_03774 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HILGINDI_03775 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HILGINDI_03776 1.8e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HILGINDI_03777 5e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HILGINDI_03778 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HILGINDI_03779 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HILGINDI_03780 1.2e-90 ywmA
HILGINDI_03781 1.3e-32 ywzB S membrane
HILGINDI_03782 1.3e-134 ywmB S TATA-box binding
HILGINDI_03783 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HILGINDI_03784 8e-188 spoIID D Stage II sporulation protein D
HILGINDI_03785 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HILGINDI_03786 3e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HILGINDI_03788 1.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HILGINDI_03789 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HILGINDI_03790 2.8e-93 S response regulator aspartate phosphatase
HILGINDI_03791 8e-82 ywmF S Peptidase M50
HILGINDI_03792 1.4e-10 csbD K CsbD-like
HILGINDI_03793 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HILGINDI_03794 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HILGINDI_03795 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HILGINDI_03796 6.1e-67 ywnA K Transcriptional regulator
HILGINDI_03797 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HILGINDI_03798 1.1e-52 ywnC S Family of unknown function (DUF5362)
HILGINDI_03799 7.1e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HILGINDI_03800 9.3e-69 ywnF S Family of unknown function (DUF5392)
HILGINDI_03801 1.5e-10 ywnC S Family of unknown function (DUF5362)
HILGINDI_03802 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HILGINDI_03803 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HILGINDI_03804 1.1e-71 ywnJ S VanZ like family
HILGINDI_03805 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HILGINDI_03806 2.4e-209 ftsW D Belongs to the SEDS family
HILGINDI_03807 2e-58 nrgB K Belongs to the P(II) protein family
HILGINDI_03808 1.2e-227 amt P Ammonium transporter
HILGINDI_03809 5.7e-103 phzA Q Isochorismatase family
HILGINDI_03810 2e-242 ywoD EGP Major facilitator superfamily
HILGINDI_03811 3.9e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HILGINDI_03812 3.8e-213 ywoG EGP Major facilitator Superfamily
HILGINDI_03813 8.5e-72 ywoH K transcriptional
HILGINDI_03814 1.8e-44 spoIIID K Stage III sporulation protein D
HILGINDI_03815 2.7e-180 mbl D Rod shape-determining protein
HILGINDI_03816 3.2e-128 flhO N flagellar basal body
HILGINDI_03817 1.4e-145 flhP N flagellar basal body
HILGINDI_03818 2.9e-201 S aspartate phosphatase
HILGINDI_03819 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HILGINDI_03820 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HILGINDI_03821 1.1e-68 ywpF S YwpF-like protein
HILGINDI_03822 4e-62 ywpG
HILGINDI_03823 3.7e-57 ssbB L Single-stranded DNA-binding protein
HILGINDI_03824 1.3e-137 glcR K DeoR C terminal sensor domain
HILGINDI_03825 3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HILGINDI_03826 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HILGINDI_03827 2.4e-308 ywqB S SWIM zinc finger
HILGINDI_03828 1.3e-14
HILGINDI_03829 5.2e-112 ywqC M biosynthesis protein
HILGINDI_03830 4.3e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HILGINDI_03831 1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HILGINDI_03832 9.5e-250 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HILGINDI_03833 1.1e-149 ywqG S Domain of unknown function (DUF1963)
HILGINDI_03835 8.5e-22 S Domain of unknown function (DUF5082)
HILGINDI_03836 9.5e-37 ywqI S Family of unknown function (DUF5344)
HILGINDI_03837 0.0 ywqJ S Pre-toxin TG
HILGINDI_03838 2e-49
HILGINDI_03839 5e-64 T DNase/tRNase domain of colicin-like bacteriocin
HILGINDI_03840 3.9e-81 S Protein of unknown function (DUF2004)
HILGINDI_03841 1.4e-88 ywqJ S Pre-toxin TG
HILGINDI_03842 8.7e-25
HILGINDI_03843 4.7e-123 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HILGINDI_03844 3.1e-156 K Transcriptional regulator
HILGINDI_03845 6.7e-93 ywqN S NAD(P)H-dependent
HILGINDI_03847 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
HILGINDI_03848 1.2e-103 ywrB P Chromate transporter
HILGINDI_03849 1.9e-83 ywrC K Transcriptional regulator
HILGINDI_03850 6.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HILGINDI_03851 2.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HILGINDI_03852 2.2e-09
HILGINDI_03853 5e-212 cotH M Spore Coat
HILGINDI_03854 7.3e-129 cotB
HILGINDI_03855 4.4e-126 ywrJ
HILGINDI_03856 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HILGINDI_03858 2e-166 alsR K LysR substrate binding domain
HILGINDI_03859 2.4e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HILGINDI_03860 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HILGINDI_03861 1.1e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HILGINDI_03862 2.2e-88 batE T Sh3 type 3 domain protein
HILGINDI_03863 5.7e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HILGINDI_03864 2.9e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
HILGINDI_03865 9.9e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HILGINDI_03866 8.1e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HILGINDI_03867 1.1e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HILGINDI_03868 1.1e-178 rbsR K transcriptional
HILGINDI_03869 1.4e-204 gerKC S Spore germination B3/ GerAC like, C-terminal
HILGINDI_03870 1.2e-189 gerKB E Spore germination protein
HILGINDI_03871 1e-183 gerKA EG Spore germination protein
HILGINDI_03872 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HILGINDI_03873 2.3e-70 pgsC S biosynthesis protein
HILGINDI_03874 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HILGINDI_03875 1.1e-19 ywtC
HILGINDI_03876 5.7e-241 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HILGINDI_03877 1.9e-34 yttA 2.7.13.3 S Pfam Transposase IS66
HILGINDI_03878 5.5e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HILGINDI_03879 1.9e-178 ywtF K Transcriptional regulator
HILGINDI_03880 1.9e-248 ywtG EGP Major facilitator Superfamily
HILGINDI_03881 8e-268 GT2,GT4 J Glycosyl transferase family 2
HILGINDI_03882 2.3e-212 gerAC S Spore germination protein
HILGINDI_03883 9.5e-195 gerBB E Spore germination protein
HILGINDI_03884 4.6e-266 gerBA EG Spore germination protein
HILGINDI_03885 3.5e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HILGINDI_03886 2.6e-243 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HILGINDI_03887 5.8e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HILGINDI_03888 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HILGINDI_03889 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HILGINDI_03890 8.6e-295 M Glycosyltransferase like family 2
HILGINDI_03891 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HILGINDI_03892 1.7e-151 tagG GM Transport permease protein
HILGINDI_03893 2.6e-283 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HILGINDI_03894 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HILGINDI_03895 9.7e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)