ORF_ID e_value Gene_name EC_number CAZy COGs Description
IEDFMFCO_00001 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEDFMFCO_00002 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
IEDFMFCO_00003 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEDFMFCO_00004 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEDFMFCO_00005 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IEDFMFCO_00006 7.4e-64 yodB K Transcriptional regulator, HxlR family
IEDFMFCO_00007 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IEDFMFCO_00008 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEDFMFCO_00009 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IEDFMFCO_00010 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEDFMFCO_00011 3.9e-99 S SdpI/YhfL protein family
IEDFMFCO_00012 4.5e-227 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IEDFMFCO_00013 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IEDFMFCO_00014 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IEDFMFCO_00015 5.2e-306 arlS 2.7.13.3 T Histidine kinase
IEDFMFCO_00016 4.3e-121 K response regulator
IEDFMFCO_00017 4.2e-245 rarA L recombination factor protein RarA
IEDFMFCO_00018 7.3e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IEDFMFCO_00019 1e-168 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEDFMFCO_00020 2.2e-89 S Peptidase propeptide and YPEB domain
IEDFMFCO_00021 1.6e-97 yceD S Uncharacterized ACR, COG1399
IEDFMFCO_00022 4.9e-218 ylbM S Belongs to the UPF0348 family
IEDFMFCO_00023 5.8e-140 yqeM Q Methyltransferase
IEDFMFCO_00024 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IEDFMFCO_00025 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IEDFMFCO_00026 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IEDFMFCO_00027 1.1e-50 yhbY J RNA-binding protein
IEDFMFCO_00028 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
IEDFMFCO_00029 1.4e-98 yqeG S HAD phosphatase, family IIIA
IEDFMFCO_00030 2.9e-79
IEDFMFCO_00031 1e-248 pgaC GT2 M Glycosyl transferase
IEDFMFCO_00032 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IEDFMFCO_00033 1e-62 hxlR K Transcriptional regulator, HxlR family
IEDFMFCO_00034 7.2e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IEDFMFCO_00035 1e-237 yrvN L AAA C-terminal domain
IEDFMFCO_00036 9.9e-57
IEDFMFCO_00037 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IEDFMFCO_00038 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IEDFMFCO_00039 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IEDFMFCO_00040 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IEDFMFCO_00041 3.3e-172 dnaI L Primosomal protein DnaI
IEDFMFCO_00042 2.5e-248 dnaB L replication initiation and membrane attachment
IEDFMFCO_00043 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IEDFMFCO_00044 7.8e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEDFMFCO_00045 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IEDFMFCO_00046 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEDFMFCO_00047 4.5e-121 ybhL S Belongs to the BI1 family
IEDFMFCO_00048 2.3e-111 hipB K Helix-turn-helix
IEDFMFCO_00049 5.5e-45 yitW S Iron-sulfur cluster assembly protein
IEDFMFCO_00050 1.4e-272 sufB O assembly protein SufB
IEDFMFCO_00051 2.7e-82 nifU C SUF system FeS assembly protein, NifU family
IEDFMFCO_00052 8.9e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEDFMFCO_00053 2.9e-243 sufD O FeS assembly protein SufD
IEDFMFCO_00054 4.2e-144 sufC O FeS assembly ATPase SufC
IEDFMFCO_00055 1.3e-34 feoA P FeoA domain
IEDFMFCO_00056 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IEDFMFCO_00057 7.9e-21 S Virus attachment protein p12 family
IEDFMFCO_00058 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IEDFMFCO_00059 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IEDFMFCO_00060 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEDFMFCO_00061 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
IEDFMFCO_00062 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IEDFMFCO_00063 7.1e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
IEDFMFCO_00064 4.8e-224 ecsB U ABC transporter
IEDFMFCO_00065 1.6e-134 ecsA V ABC transporter, ATP-binding protein
IEDFMFCO_00066 9.9e-82 hit FG histidine triad
IEDFMFCO_00067 3.5e-39
IEDFMFCO_00068 2.4e-127 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IEDFMFCO_00069 3.5e-78 S WxL domain surface cell wall-binding
IEDFMFCO_00070 3.4e-102 S WxL domain surface cell wall-binding
IEDFMFCO_00071 1.4e-192 S Fn3-like domain
IEDFMFCO_00072 7.9e-61
IEDFMFCO_00073 0.0
IEDFMFCO_00074 9.4e-242 npr 1.11.1.1 C NADH oxidase
IEDFMFCO_00075 3.3e-112 K Bacterial regulatory proteins, tetR family
IEDFMFCO_00076 5.1e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IEDFMFCO_00077 9.4e-106
IEDFMFCO_00078 9.3e-106 GBS0088 S Nucleotidyltransferase
IEDFMFCO_00079 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IEDFMFCO_00080 1.5e-222 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IEDFMFCO_00081 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IEDFMFCO_00082 1.1e-171 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEDFMFCO_00083 0.0 S membrane
IEDFMFCO_00084 3.9e-69 S NUDIX domain
IEDFMFCO_00085 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IEDFMFCO_00086 1.8e-184 ykoT GT2 M Glycosyl transferase family 2
IEDFMFCO_00087 1.3e-79 dedA S SNARE-like domain protein
IEDFMFCO_00088 2.6e-132 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IEDFMFCO_00089 2.2e-61 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatase
IEDFMFCO_00090 4.8e-104 K Transcriptional regulatory protein, C terminal
IEDFMFCO_00091 1.9e-160 T PhoQ Sensor
IEDFMFCO_00092 6e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
IEDFMFCO_00093 4.2e-98
IEDFMFCO_00094 0.0 1.3.5.4 C FAD binding domain
IEDFMFCO_00095 6.2e-111 1.3.5.4 S NADPH-dependent FMN reductase
IEDFMFCO_00096 1.2e-177 K LysR substrate binding domain
IEDFMFCO_00097 5.2e-181 3.4.21.102 M Peptidase family S41
IEDFMFCO_00098 8.7e-215
IEDFMFCO_00099 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
IEDFMFCO_00100 0.0 L AAA domain
IEDFMFCO_00101 5.7e-233 yhaO L Ser Thr phosphatase family protein
IEDFMFCO_00102 1e-54 yheA S Belongs to the UPF0342 family
IEDFMFCO_00103 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IEDFMFCO_00104 2.9e-12
IEDFMFCO_00105 4.4e-77 argR K Regulates arginine biosynthesis genes
IEDFMFCO_00106 3.2e-214 arcT 2.6.1.1 E Aminotransferase
IEDFMFCO_00107 1.4e-102 argO S LysE type translocator
IEDFMFCO_00108 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
IEDFMFCO_00109 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFMFCO_00110 2e-114 M ErfK YbiS YcfS YnhG
IEDFMFCO_00111 1.1e-204 EGP Major facilitator Superfamily
IEDFMFCO_00112 4.4e-288 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_00113 1.6e-244 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_00114 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IEDFMFCO_00115 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IEDFMFCO_00116 8.5e-60 S Domain of unknown function (DUF3284)
IEDFMFCO_00117 0.0 K PRD domain
IEDFMFCO_00118 7.6e-107
IEDFMFCO_00119 0.0 yhcA V MacB-like periplasmic core domain
IEDFMFCO_00120 1.4e-81
IEDFMFCO_00121 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IEDFMFCO_00122 7.7e-79 elaA S Acetyltransferase (GNAT) domain
IEDFMFCO_00125 1.9e-31
IEDFMFCO_00126 2.1e-244 dinF V MatE
IEDFMFCO_00127 0.0 yfbS P Sodium:sulfate symporter transmembrane region
IEDFMFCO_00128 1.1e-303 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
IEDFMFCO_00129 5.5e-175 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
IEDFMFCO_00130 2.5e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
IEDFMFCO_00131 1.3e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
IEDFMFCO_00132 1e-218 S Protein conserved in bacteria
IEDFMFCO_00133 6e-73 S Protein conserved in bacteria
IEDFMFCO_00134 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IEDFMFCO_00135 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IEDFMFCO_00136 3.6e-58 S Protein of unknown function (DUF1516)
IEDFMFCO_00137 1.9e-89 gtcA S Teichoic acid glycosylation protein
IEDFMFCO_00138 2.1e-180
IEDFMFCO_00139 3.5e-10
IEDFMFCO_00140 5.9e-52
IEDFMFCO_00143 3.3e-37 S Haemolysin XhlA
IEDFMFCO_00144 3.7e-177 3.5.1.28 M Glycosyl hydrolases family 25
IEDFMFCO_00145 4.5e-53
IEDFMFCO_00148 2.4e-160
IEDFMFCO_00149 2.3e-294 S Phage minor structural protein
IEDFMFCO_00150 1.3e-225 S Phage tail protein
IEDFMFCO_00151 0.0 S peptidoglycan catabolic process
IEDFMFCO_00154 1e-71 S Phage tail tube protein
IEDFMFCO_00155 5.9e-27
IEDFMFCO_00156 9.1e-40
IEDFMFCO_00157 1.4e-25 S Phage head-tail joining protein
IEDFMFCO_00158 3.6e-52 S Phage gp6-like head-tail connector protein
IEDFMFCO_00159 2.6e-209 S Phage capsid family
IEDFMFCO_00160 8.4e-126 S Clp protease
IEDFMFCO_00161 6.2e-224 S Phage portal protein
IEDFMFCO_00162 1.1e-24 S Protein of unknown function (DUF1056)
IEDFMFCO_00163 0.0 S Phage Terminase
IEDFMFCO_00164 4.7e-79 L Phage terminase, small subunit
IEDFMFCO_00165 5.2e-29 S HNH endonuclease
IEDFMFCO_00166 6.4e-69 L HNH nucleases
IEDFMFCO_00167 8.6e-13
IEDFMFCO_00169 4.3e-64 S Transcriptional regulator, RinA family
IEDFMFCO_00170 1.4e-17
IEDFMFCO_00172 8.2e-26 S YopX protein
IEDFMFCO_00173 4.1e-17
IEDFMFCO_00174 7.8e-46
IEDFMFCO_00176 2.4e-144 pi346 L IstB-like ATP binding protein
IEDFMFCO_00177 3.6e-71 L DnaD domain protein
IEDFMFCO_00178 4.6e-131 S Putative HNHc nuclease
IEDFMFCO_00183 8.9e-56 S Domain of unknown function (DUF771)
IEDFMFCO_00184 1.3e-06
IEDFMFCO_00186 1.3e-62 S ORF6C domain
IEDFMFCO_00188 8e-25 ps115 K Helix-turn-helix XRE-family like proteins
IEDFMFCO_00189 1.5e-36 S Pfam:Peptidase_M78
IEDFMFCO_00196 2.6e-211 L Belongs to the 'phage' integrase family
IEDFMFCO_00198 0.0 uvrA2 L ABC transporter
IEDFMFCO_00199 2.5e-46
IEDFMFCO_00200 1.9e-89
IEDFMFCO_00201 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
IEDFMFCO_00202 1e-67 S CAAX protease self-immunity
IEDFMFCO_00203 1.2e-36 S CAAX protease self-immunity
IEDFMFCO_00204 2.5e-59
IEDFMFCO_00205 4.5e-55
IEDFMFCO_00206 1.6e-137 pltR K LytTr DNA-binding domain
IEDFMFCO_00207 2.2e-224 pltK 2.7.13.3 T GHKL domain
IEDFMFCO_00208 1.7e-108
IEDFMFCO_00209 7.6e-149 S Sucrose-6F-phosphate phosphohydrolase
IEDFMFCO_00210 1.2e-158 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IEDFMFCO_00211 3.5e-117 GM NAD(P)H-binding
IEDFMFCO_00212 6.6e-60 K helix_turn_helix, mercury resistance
IEDFMFCO_00213 9.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IEDFMFCO_00214 4e-176 K LytTr DNA-binding domain
IEDFMFCO_00215 2.3e-156 V ABC transporter
IEDFMFCO_00216 2.5e-127 V Transport permease protein
IEDFMFCO_00218 1.8e-179 XK27_06930 V domain protein
IEDFMFCO_00219 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IEDFMFCO_00220 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
IEDFMFCO_00221 9.9e-126 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IEDFMFCO_00222 5.9e-140 ugpB G Bacterial extracellular solute-binding protein
IEDFMFCO_00223 2.3e-108 ugpB G Bacterial extracellular solute-binding protein
IEDFMFCO_00224 1.1e-150 ugpE G ABC transporter permease
IEDFMFCO_00225 6.8e-173 ugpA U Binding-protein-dependent transport system inner membrane component
IEDFMFCO_00226 1.8e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
IEDFMFCO_00227 4.1e-84 uspA T Belongs to the universal stress protein A family
IEDFMFCO_00228 1.5e-272 pepV 3.5.1.18 E dipeptidase PepV
IEDFMFCO_00229 6.4e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IEDFMFCO_00230 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IEDFMFCO_00231 3e-301 ytgP S Polysaccharide biosynthesis protein
IEDFMFCO_00232 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEDFMFCO_00233 6.7e-124 3.6.1.27 I Acid phosphatase homologues
IEDFMFCO_00234 1e-93 ytqB 2.1.1.176 J Putative rRNA methylase
IEDFMFCO_00235 7.2e-29
IEDFMFCO_00236 2.4e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IEDFMFCO_00237 1.8e-268 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
IEDFMFCO_00238 0.0 S Pfam Methyltransferase
IEDFMFCO_00240 3.6e-139 N Cell shape-determining protein MreB
IEDFMFCO_00241 1.4e-278 bmr3 EGP Major facilitator Superfamily
IEDFMFCO_00242 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IEDFMFCO_00243 3.1e-122
IEDFMFCO_00244 1.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
IEDFMFCO_00245 1.9e-167 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IEDFMFCO_00246 6.6e-254 mmuP E amino acid
IEDFMFCO_00247 4.4e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IEDFMFCO_00248 1.3e-230 mntH P H( )-stimulated, divalent metal cation uptake system
IEDFMFCO_00250 2.9e-156 T Calcineurin-like phosphoesterase superfamily domain
IEDFMFCO_00251 2e-94 K Acetyltransferase (GNAT) domain
IEDFMFCO_00252 1.4e-95
IEDFMFCO_00253 2e-181 P secondary active sulfate transmembrane transporter activity
IEDFMFCO_00254 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
IEDFMFCO_00260 5.1e-08
IEDFMFCO_00265 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IEDFMFCO_00266 1.2e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IEDFMFCO_00267 2e-146
IEDFMFCO_00268 1e-138 htpX O Belongs to the peptidase M48B family
IEDFMFCO_00269 1.7e-91 lemA S LemA family
IEDFMFCO_00270 9.2e-127 srtA 3.4.22.70 M sortase family
IEDFMFCO_00271 9.4e-214 J translation release factor activity
IEDFMFCO_00272 7.8e-41 rpmE2 J Ribosomal protein L31
IEDFMFCO_00273 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IEDFMFCO_00274 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEDFMFCO_00275 2.5e-26
IEDFMFCO_00276 6.4e-131 S YheO-like PAS domain
IEDFMFCO_00277 2.2e-157 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IEDFMFCO_00278 3.7e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IEDFMFCO_00279 6.8e-229 tdcC E amino acid
IEDFMFCO_00280 1.7e-243 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IEDFMFCO_00281 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IEDFMFCO_00282 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IEDFMFCO_00283 3.8e-78 ywiB S Domain of unknown function (DUF1934)
IEDFMFCO_00284 3.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IEDFMFCO_00285 9e-264 ywfO S HD domain protein
IEDFMFCO_00286 3.7e-148 yxeH S hydrolase
IEDFMFCO_00287 2.2e-126
IEDFMFCO_00288 1.2e-183 S DUF218 domain
IEDFMFCO_00289 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEDFMFCO_00290 1.8e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
IEDFMFCO_00291 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IEDFMFCO_00292 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IEDFMFCO_00293 2.1e-31
IEDFMFCO_00294 6.4e-43 ankB S ankyrin repeats
IEDFMFCO_00295 9.2e-131 znuB U ABC 3 transport family
IEDFMFCO_00296 9.8e-129 fhuC 3.6.3.35 P ABC transporter
IEDFMFCO_00297 1.3e-181 S Prolyl oligopeptidase family
IEDFMFCO_00298 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IEDFMFCO_00299 3.2e-37 veg S Biofilm formation stimulator VEG
IEDFMFCO_00300 3.9e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IEDFMFCO_00301 2.6e-95 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IEDFMFCO_00302 1.5e-146 tatD L hydrolase, TatD family
IEDFMFCO_00303 9.2e-212 bcr1 EGP Major facilitator Superfamily
IEDFMFCO_00304 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEDFMFCO_00305 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
IEDFMFCO_00306 2e-160 yunF F Protein of unknown function DUF72
IEDFMFCO_00307 8.6e-133 cobB K SIR2 family
IEDFMFCO_00308 3.1e-178
IEDFMFCO_00309 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IEDFMFCO_00310 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IEDFMFCO_00311 3.5e-151 S Psort location Cytoplasmic, score
IEDFMFCO_00312 1.1e-206
IEDFMFCO_00313 8.1e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEDFMFCO_00314 1.6e-132 K Helix-turn-helix domain, rpiR family
IEDFMFCO_00315 1e-162 GK ROK family
IEDFMFCO_00316 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_00317 1.5e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_00318 2.6e-76 S Domain of unknown function (DUF3284)
IEDFMFCO_00319 3.9e-24
IEDFMFCO_00320 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_00321 9e-130 K UbiC transcription regulator-associated domain protein
IEDFMFCO_00322 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEDFMFCO_00323 1.2e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IEDFMFCO_00324 0.0 helD 3.6.4.12 L DNA helicase
IEDFMFCO_00325 2.6e-29
IEDFMFCO_00326 1e-114 S CAAX protease self-immunity
IEDFMFCO_00327 4.7e-112 V CAAX protease self-immunity
IEDFMFCO_00328 1.6e-120 ypbD S CAAX protease self-immunity
IEDFMFCO_00329 5.5e-95 S CAAX protease self-immunity
IEDFMFCO_00330 1.4e-243 mesE M Transport protein ComB
IEDFMFCO_00331 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IEDFMFCO_00332 5.9e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IEDFMFCO_00333 1.2e-103
IEDFMFCO_00334 5.1e-259 ica2 GT2 M Glycosyl transferase family group 2
IEDFMFCO_00335 1.4e-292
IEDFMFCO_00336 6.3e-205 ftsW D Belongs to the SEDS family
IEDFMFCO_00337 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IEDFMFCO_00338 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IEDFMFCO_00339 5.3e-101 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IEDFMFCO_00340 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IEDFMFCO_00341 9.6e-197 ylbL T Belongs to the peptidase S16 family
IEDFMFCO_00342 4.7e-126 comEA L Competence protein ComEA
IEDFMFCO_00343 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
IEDFMFCO_00344 0.0 comEC S Competence protein ComEC
IEDFMFCO_00345 4.8e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
IEDFMFCO_00346 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
IEDFMFCO_00347 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IEDFMFCO_00348 1.3e-192 mdtG EGP Major Facilitator Superfamily
IEDFMFCO_00349 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEDFMFCO_00350 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEDFMFCO_00351 9.1e-159 S Tetratricopeptide repeat
IEDFMFCO_00352 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEDFMFCO_00353 4.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IEDFMFCO_00354 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IEDFMFCO_00355 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IEDFMFCO_00356 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IEDFMFCO_00357 9.9e-73 S Iron-sulphur cluster biosynthesis
IEDFMFCO_00358 4.3e-22
IEDFMFCO_00359 9.2e-270 glnPH2 P ABC transporter permease
IEDFMFCO_00360 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IEDFMFCO_00361 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IEDFMFCO_00362 2.9e-126 epsB M biosynthesis protein
IEDFMFCO_00363 7.3e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IEDFMFCO_00364 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
IEDFMFCO_00365 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
IEDFMFCO_00366 7.9e-128 tuaA M Bacterial sugar transferase
IEDFMFCO_00367 1.2e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
IEDFMFCO_00368 2.9e-190 cps4G M Glycosyltransferase Family 4
IEDFMFCO_00369 1.6e-233
IEDFMFCO_00370 1.7e-176 cps4I M Glycosyltransferase like family 2
IEDFMFCO_00371 1.4e-262 cps4J S Polysaccharide biosynthesis protein
IEDFMFCO_00372 1e-251 cpdA S Calcineurin-like phosphoesterase
IEDFMFCO_00373 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
IEDFMFCO_00374 1.8e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IEDFMFCO_00375 1.5e-135 fruR K DeoR C terminal sensor domain
IEDFMFCO_00376 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IEDFMFCO_00377 3.2e-46
IEDFMFCO_00378 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IEDFMFCO_00379 1.5e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFMFCO_00380 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
IEDFMFCO_00381 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IEDFMFCO_00382 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IEDFMFCO_00383 2.9e-102 K Helix-turn-helix domain
IEDFMFCO_00384 7.2e-212 EGP Major facilitator Superfamily
IEDFMFCO_00385 8.5e-57 ybjQ S Belongs to the UPF0145 family
IEDFMFCO_00386 5.8e-143 Q Methyltransferase
IEDFMFCO_00387 1.6e-31
IEDFMFCO_00389 1.5e-36 2.7.7.1, 3.6.1.55 F Hydrolase, nudix family
IEDFMFCO_00391 4.5e-230 rodA D Cell cycle protein
IEDFMFCO_00392 4.1e-42 opuAB P Binding-protein-dependent transport system inner membrane component
IEDFMFCO_00393 4.5e-42 opuAB P Binding-protein-dependent transport system inner membrane component
IEDFMFCO_00394 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
IEDFMFCO_00395 2.4e-243 P Sodium:sulfate symporter transmembrane region
IEDFMFCO_00396 6.4e-165 K LysR substrate binding domain
IEDFMFCO_00397 4.4e-79
IEDFMFCO_00398 4.9e-22
IEDFMFCO_00399 7.6e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEDFMFCO_00400 5.8e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IEDFMFCO_00401 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IEDFMFCO_00402 2e-80
IEDFMFCO_00403 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IEDFMFCO_00404 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IEDFMFCO_00405 3.1e-127 yliE T EAL domain
IEDFMFCO_00406 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
IEDFMFCO_00407 2.2e-88 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IEDFMFCO_00408 5.6e-39 S Cytochrome B5
IEDFMFCO_00409 1.6e-237
IEDFMFCO_00410 1.3e-128 treR K UTRA
IEDFMFCO_00411 2.4e-158 I alpha/beta hydrolase fold
IEDFMFCO_00412 4.3e-255 npp S type I phosphodiesterase nucleotide pyrophosphatase
IEDFMFCO_00413 9.9e-233 yxiO S Vacuole effluxer Atg22 like
IEDFMFCO_00414 2.4e-172 ropB K Helix-turn-helix XRE-family like proteins
IEDFMFCO_00415 2.4e-207 EGP Major facilitator Superfamily
IEDFMFCO_00416 0.0 uvrA3 L excinuclease ABC
IEDFMFCO_00417 0.0 S Predicted membrane protein (DUF2207)
IEDFMFCO_00418 1.1e-147 3.1.3.102, 3.1.3.104 S hydrolase
IEDFMFCO_00419 2.7e-307 ybiT S ABC transporter, ATP-binding protein
IEDFMFCO_00420 1.7e-221 S CAAX protease self-immunity
IEDFMFCO_00421 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
IEDFMFCO_00422 2.1e-102 speG J Acetyltransferase (GNAT) domain
IEDFMFCO_00423 8.8e-141 endA F DNA RNA non-specific endonuclease
IEDFMFCO_00424 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
IEDFMFCO_00425 1.1e-95 K Transcriptional regulator (TetR family)
IEDFMFCO_00426 1e-175 yhgE V domain protein
IEDFMFCO_00427 6.4e-08
IEDFMFCO_00429 7.4e-245 EGP Major facilitator Superfamily
IEDFMFCO_00430 0.0 mdlA V ABC transporter
IEDFMFCO_00431 0.0 mdlB V ABC transporter
IEDFMFCO_00433 6.3e-193 C Aldo/keto reductase family
IEDFMFCO_00434 9.7e-102 M Protein of unknown function (DUF3737)
IEDFMFCO_00435 5.7e-222 patB 4.4.1.8 E Aminotransferase, class I
IEDFMFCO_00436 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IEDFMFCO_00437 1.5e-81
IEDFMFCO_00438 1.9e-124 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IEDFMFCO_00439 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IEDFMFCO_00440 6.1e-76 T Belongs to the universal stress protein A family
IEDFMFCO_00441 5.7e-83 GM NAD(P)H-binding
IEDFMFCO_00442 1.3e-142 EGP Major Facilitator Superfamily
IEDFMFCO_00443 1.5e-142 akr5f 1.1.1.346 S reductase
IEDFMFCO_00444 1.3e-130 C Aldo keto reductase
IEDFMFCO_00445 2.5e-114 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFMFCO_00446 4.4e-10 adhR K helix_turn_helix, mercury resistance
IEDFMFCO_00447 3e-25 fldA C Flavodoxin
IEDFMFCO_00449 2e-78 K Transcriptional regulator
IEDFMFCO_00450 6.4e-109 akr5f 1.1.1.346 S reductase
IEDFMFCO_00451 2.5e-86 GM NAD(P)H-binding
IEDFMFCO_00452 1.4e-84 glcU U sugar transport
IEDFMFCO_00453 3e-126 IQ reductase
IEDFMFCO_00454 4.2e-76 darA C Flavodoxin
IEDFMFCO_00455 3.3e-82 yiiE S Protein of unknown function (DUF1211)
IEDFMFCO_00456 3.1e-48 aRA11 1.1.1.346 S reductase
IEDFMFCO_00457 6.8e-76 aRA11 1.1.1.346 S reductase
IEDFMFCO_00458 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
IEDFMFCO_00459 2.3e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IEDFMFCO_00460 1.2e-103 GM NAD(P)H-binding
IEDFMFCO_00461 2.8e-157 K LysR substrate binding domain
IEDFMFCO_00462 8.4e-60 S Domain of unknown function (DUF4440)
IEDFMFCO_00463 5.8e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
IEDFMFCO_00464 8.2e-48
IEDFMFCO_00465 7e-37
IEDFMFCO_00466 7.3e-86 yvbK 3.1.3.25 K GNAT family
IEDFMFCO_00467 2.4e-83
IEDFMFCO_00468 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IEDFMFCO_00469 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IEDFMFCO_00470 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEDFMFCO_00472 3.7e-120 macB V ABC transporter, ATP-binding protein
IEDFMFCO_00473 0.0 ylbB V ABC transporter permease
IEDFMFCO_00474 2.3e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IEDFMFCO_00475 4.4e-79 K transcriptional regulator, MerR family
IEDFMFCO_00476 3.2e-76 yphH S Cupin domain
IEDFMFCO_00477 6.6e-56 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
IEDFMFCO_00478 1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFMFCO_00479 1.2e-211 natB CP ABC-2 family transporter protein
IEDFMFCO_00480 3.6e-168 natA S ABC transporter, ATP-binding protein
IEDFMFCO_00481 8.2e-96 wecD K Acetyltransferase (GNAT) family
IEDFMFCO_00482 5.6e-115 ylbE GM NAD(P)H-binding
IEDFMFCO_00483 9.5e-161 mleR K LysR family
IEDFMFCO_00484 1.7e-126 S membrane transporter protein
IEDFMFCO_00485 3e-18
IEDFMFCO_00486 4e-104 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEDFMFCO_00487 1.4e-217 patA 2.6.1.1 E Aminotransferase
IEDFMFCO_00488 5.5e-261 gabR K Bacterial regulatory proteins, gntR family
IEDFMFCO_00489 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IEDFMFCO_00490 8.5e-57 S SdpI/YhfL protein family
IEDFMFCO_00491 5.1e-173 C Zinc-binding dehydrogenase
IEDFMFCO_00492 1.2e-61 K helix_turn_helix, mercury resistance
IEDFMFCO_00493 1.1e-212 yttB EGP Major facilitator Superfamily
IEDFMFCO_00494 2.6e-270 yjcE P Sodium proton antiporter
IEDFMFCO_00495 4.9e-87 nrdI F Belongs to the NrdI family
IEDFMFCO_00496 1.8e-240 yhdP S Transporter associated domain
IEDFMFCO_00497 4.4e-58
IEDFMFCO_00498 7e-74 hspX O Belongs to the small heat shock protein (HSP20) family
IEDFMFCO_00499 4.5e-61
IEDFMFCO_00500 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
IEDFMFCO_00501 5.5e-138 rrp8 K LytTr DNA-binding domain
IEDFMFCO_00502 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IEDFMFCO_00503 2e-138
IEDFMFCO_00504 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEDFMFCO_00505 2.4e-130 gntR2 K Transcriptional regulator
IEDFMFCO_00506 4e-161 S Putative esterase
IEDFMFCO_00507 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IEDFMFCO_00508 1e-223 lsgC M Glycosyl transferases group 1
IEDFMFCO_00509 1e-19 S Protein of unknown function (DUF2929)
IEDFMFCO_00510 1.7e-48 K Cro/C1-type HTH DNA-binding domain
IEDFMFCO_00511 1.9e-156 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IEDFMFCO_00512 1.6e-79 uspA T universal stress protein
IEDFMFCO_00513 2e-129 K UTRA domain
IEDFMFCO_00514 1.2e-85 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
IEDFMFCO_00515 4.7e-143 agaC G PTS system sorbose-specific iic component
IEDFMFCO_00516 3.2e-147 G PTS system mannose/fructose/sorbose family IID component
IEDFMFCO_00517 3e-72 G PTS system fructose IIA component
IEDFMFCO_00518 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
IEDFMFCO_00519 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
IEDFMFCO_00520 4e-60
IEDFMFCO_00521 1.7e-73
IEDFMFCO_00522 5e-82 yybC S Protein of unknown function (DUF2798)
IEDFMFCO_00523 6.3e-45
IEDFMFCO_00524 5.2e-47
IEDFMFCO_00525 4.2e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IEDFMFCO_00526 6.6e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
IEDFMFCO_00527 8.4e-145 yjfP S Dienelactone hydrolase family
IEDFMFCO_00528 5.4e-68
IEDFMFCO_00529 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IEDFMFCO_00530 2.6e-48
IEDFMFCO_00531 1.3e-57
IEDFMFCO_00532 3e-164
IEDFMFCO_00533 1.3e-72 K Transcriptional regulator
IEDFMFCO_00534 0.0 pepF2 E Oligopeptidase F
IEDFMFCO_00535 7e-175 D Alpha beta
IEDFMFCO_00536 1.2e-45 S Enterocin A Immunity
IEDFMFCO_00537 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
IEDFMFCO_00538 5.1e-125 skfE V ABC transporter
IEDFMFCO_00539 2.7e-132
IEDFMFCO_00540 3.7e-107 pncA Q Isochorismatase family
IEDFMFCO_00541 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IEDFMFCO_00542 0.0 yjcE P Sodium proton antiporter
IEDFMFCO_00543 5.9e-199 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
IEDFMFCO_00544 1.9e-175 S Oxidoreductase family, NAD-binding Rossmann fold
IEDFMFCO_00545 1e-156 K Helix-turn-helix domain, rpiR family
IEDFMFCO_00546 6.4e-176 ccpB 5.1.1.1 K lacI family
IEDFMFCO_00547 4.2e-141 S Sucrose-6F-phosphate phosphohydrolase
IEDFMFCO_00548 1.5e-124 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
IEDFMFCO_00549 1.8e-178 K sugar-binding domain protein
IEDFMFCO_00550 0.0 ybiW 2.3.1.54 C Pyruvate formate lyase-like
IEDFMFCO_00551 3.7e-134 yciT K DeoR C terminal sensor domain
IEDFMFCO_00552 3.7e-156 pflC 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IEDFMFCO_00553 3.1e-89 bglK_1 GK ROK family
IEDFMFCO_00554 5.9e-73 bglK_1 GK ROK family
IEDFMFCO_00555 9e-153 glcU U sugar transport
IEDFMFCO_00556 3.4e-150 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEDFMFCO_00557 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
IEDFMFCO_00558 2.5e-98 drgA C Nitroreductase family
IEDFMFCO_00559 3.6e-168 S Polyphosphate kinase 2 (PPK2)
IEDFMFCO_00560 2.3e-181 3.6.4.13 S domain, Protein
IEDFMFCO_00561 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
IEDFMFCO_00562 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IEDFMFCO_00563 0.0 glpQ 3.1.4.46 C phosphodiesterase
IEDFMFCO_00564 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IEDFMFCO_00565 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
IEDFMFCO_00566 7.2e-289 M domain protein
IEDFMFCO_00567 0.0 ydgH S MMPL family
IEDFMFCO_00568 3.2e-112 S Protein of unknown function (DUF1211)
IEDFMFCO_00569 3.7e-34
IEDFMFCO_00570 2e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IEDFMFCO_00571 8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IEDFMFCO_00572 3.5e-13 rmeB K transcriptional regulator, MerR family
IEDFMFCO_00573 3.4e-50 S Domain of unknown function (DU1801)
IEDFMFCO_00574 1.7e-165 corA P CorA-like Mg2+ transporter protein
IEDFMFCO_00575 4.6e-216 ysaA V RDD family
IEDFMFCO_00576 3.2e-163 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
IEDFMFCO_00577 1.3e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IEDFMFCO_00578 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IEDFMFCO_00579 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IEDFMFCO_00580 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IEDFMFCO_00581 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IEDFMFCO_00582 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IEDFMFCO_00583 6.4e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IEDFMFCO_00584 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IEDFMFCO_00585 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IEDFMFCO_00586 3.3e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IEDFMFCO_00587 1.2e-84 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IEDFMFCO_00588 4.8e-137 terC P membrane
IEDFMFCO_00589 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IEDFMFCO_00590 2.1e-277 C Electron transfer flavoprotein FAD-binding domain
IEDFMFCO_00591 1.6e-117 K Transcriptional regulator
IEDFMFCO_00592 7.2e-300 M Exporter of polyketide antibiotics
IEDFMFCO_00593 2.3e-170 yjjC V ABC transporter
IEDFMFCO_00594 5.5e-144 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IEDFMFCO_00595 9.1e-89
IEDFMFCO_00596 7.6e-149
IEDFMFCO_00597 4.6e-143
IEDFMFCO_00598 8.3e-54 K Transcriptional regulator PadR-like family
IEDFMFCO_00599 1.6e-129 K UbiC transcription regulator-associated domain protein
IEDFMFCO_00600 2.5e-98 S UPF0397 protein
IEDFMFCO_00601 0.0 ykoD P ABC transporter, ATP-binding protein
IEDFMFCO_00602 1.9e-150 cbiQ P cobalt transport
IEDFMFCO_00603 1.2e-208 C Oxidoreductase
IEDFMFCO_00604 7.5e-259
IEDFMFCO_00605 2.1e-50
IEDFMFCO_00606 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
IEDFMFCO_00607 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
IEDFMFCO_00608 1.2e-165 1.1.1.65 C Aldo keto reductase
IEDFMFCO_00609 7.6e-160 S reductase
IEDFMFCO_00611 8.1e-216 yeaN P Transporter, major facilitator family protein
IEDFMFCO_00612 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
IEDFMFCO_00613 4.7e-227 mdtG EGP Major facilitator Superfamily
IEDFMFCO_00614 1.1e-74 K LytTr DNA-binding domain
IEDFMFCO_00615 8.7e-30 S Protein of unknown function (DUF3021)
IEDFMFCO_00616 1.7e-72 hsp1 O Belongs to the small heat shock protein (HSP20) family
IEDFMFCO_00617 1.2e-74 papX3 K Transcriptional regulator
IEDFMFCO_00618 7.2e-112 S NADPH-dependent FMN reductase
IEDFMFCO_00619 1.6e-28 KT PspC domain
IEDFMFCO_00620 6e-140 2.4.2.3 F Phosphorylase superfamily
IEDFMFCO_00621 0.0 pacL1 P P-type ATPase
IEDFMFCO_00622 1.1e-149 ydjP I Alpha/beta hydrolase family
IEDFMFCO_00623 2.4e-122
IEDFMFCO_00624 2.6e-250 yifK E Amino acid permease
IEDFMFCO_00625 3.4e-85 F NUDIX domain
IEDFMFCO_00626 7.3e-305 L HIRAN domain
IEDFMFCO_00627 1.6e-137 S peptidase C26
IEDFMFCO_00628 1.3e-208 cytX U Belongs to the purine-cytosine permease (2.A.39) family
IEDFMFCO_00629 5.6e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IEDFMFCO_00630 3.2e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IEDFMFCO_00631 2e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IEDFMFCO_00632 1e-176 1.6.5.5 C Zinc-binding dehydrogenase
IEDFMFCO_00633 2.8e-151 larE S NAD synthase
IEDFMFCO_00634 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IEDFMFCO_00635 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
IEDFMFCO_00636 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IEDFMFCO_00637 2.4e-125 larB S AIR carboxylase
IEDFMFCO_00638 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
IEDFMFCO_00639 4.2e-121 K Crp-like helix-turn-helix domain
IEDFMFCO_00640 4.8e-182 nikMN P PDGLE domain
IEDFMFCO_00641 3.1e-150 P Cobalt transport protein
IEDFMFCO_00642 2.1e-129 cbiO P ABC transporter
IEDFMFCO_00643 4.8e-40
IEDFMFCO_00644 1.8e-144 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
IEDFMFCO_00646 1.6e-140
IEDFMFCO_00647 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
IEDFMFCO_00648 6e-76
IEDFMFCO_00649 1.6e-140 S Belongs to the UPF0246 family
IEDFMFCO_00650 1.8e-169 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IEDFMFCO_00651 4.4e-35 yyaN K MerR HTH family regulatory protein
IEDFMFCO_00652 1.3e-120 azlC E branched-chain amino acid
IEDFMFCO_00653 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
IEDFMFCO_00654 0.0 asnB 6.3.5.4 E Asparagine synthase
IEDFMFCO_00655 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
IEDFMFCO_00656 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEDFMFCO_00657 1.5e-253 xylP2 G symporter
IEDFMFCO_00658 1.3e-190 nlhH_1 I alpha/beta hydrolase fold
IEDFMFCO_00659 5.6e-49
IEDFMFCO_00660 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IEDFMFCO_00661 2.6e-103 3.2.2.20 K FR47-like protein
IEDFMFCO_00662 1.3e-126 yibF S overlaps another CDS with the same product name
IEDFMFCO_00663 1.9e-220 yibE S overlaps another CDS with the same product name
IEDFMFCO_00664 2.3e-179
IEDFMFCO_00665 1.3e-137 S NADPH-dependent FMN reductase
IEDFMFCO_00666 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
IEDFMFCO_00667 2.9e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IEDFMFCO_00668 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IEDFMFCO_00669 4.1e-32 L leucine-zipper of insertion element IS481
IEDFMFCO_00670 8.5e-41
IEDFMFCO_00671 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IEDFMFCO_00672 3.3e-277 pipD E Dipeptidase
IEDFMFCO_00673 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
IEDFMFCO_00674 1.1e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IEDFMFCO_00675 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEDFMFCO_00676 2.3e-81 rmaD K Transcriptional regulator
IEDFMFCO_00678 0.0 1.3.5.4 C FMN_bind
IEDFMFCO_00679 6.1e-171 K Transcriptional regulator
IEDFMFCO_00680 1.1e-95 K Helix-turn-helix domain
IEDFMFCO_00681 4.5e-140 K sequence-specific DNA binding
IEDFMFCO_00682 1e-87 S AAA domain
IEDFMFCO_00684 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
IEDFMFCO_00685 1e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
IEDFMFCO_00686 3.4e-51 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
IEDFMFCO_00687 1.1e-169 L Belongs to the 'phage' integrase family
IEDFMFCO_00688 4.6e-70 3.1.21.3 V Type I restriction modification DNA specificity domain
IEDFMFCO_00689 8.2e-179 hsdM 2.1.1.72 V type I restriction-modification system
IEDFMFCO_00690 2.2e-108 hsdM 2.1.1.72 V type I restriction-modification system
IEDFMFCO_00691 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IEDFMFCO_00692 0.0 pepN 3.4.11.2 E aminopeptidase
IEDFMFCO_00693 4.1e-101 G Glycogen debranching enzyme
IEDFMFCO_00694 5.3e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IEDFMFCO_00695 2.7e-156 yjdB S Domain of unknown function (DUF4767)
IEDFMFCO_00696 2.6e-149 Q Fumarylacetoacetate (FAA) hydrolase family
IEDFMFCO_00697 5.3e-72 asp2 S Asp23 family, cell envelope-related function
IEDFMFCO_00698 8.7e-72 asp S Asp23 family, cell envelope-related function
IEDFMFCO_00699 7.2e-23
IEDFMFCO_00700 2.6e-84
IEDFMFCO_00701 7.1e-37 S Transglycosylase associated protein
IEDFMFCO_00702 0.0 XK27_09800 I Acyltransferase family
IEDFMFCO_00703 5.7e-38 S MORN repeat
IEDFMFCO_00704 1.9e-48
IEDFMFCO_00705 8.7e-153 S Domain of unknown function (DUF4767)
IEDFMFCO_00706 3.4e-66
IEDFMFCO_00707 2.1e-174 corA P CorA-like Mg2+ transporter protein
IEDFMFCO_00708 1.9e-62 S Protein of unknown function (DUF3397)
IEDFMFCO_00709 1.9e-77 mraZ K Belongs to the MraZ family
IEDFMFCO_00710 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IEDFMFCO_00711 7.5e-54 ftsL D Cell division protein FtsL
IEDFMFCO_00712 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IEDFMFCO_00713 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IEDFMFCO_00714 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IEDFMFCO_00715 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IEDFMFCO_00716 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IEDFMFCO_00717 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IEDFMFCO_00718 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEDFMFCO_00719 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IEDFMFCO_00720 1.2e-36 yggT S YGGT family
IEDFMFCO_00721 3.4e-146 ylmH S S4 domain protein
IEDFMFCO_00722 1.2e-86 divIVA D DivIVA domain protein
IEDFMFCO_00723 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEDFMFCO_00724 8.8e-79 cylA V abc transporter atp-binding protein
IEDFMFCO_00725 2.3e-79 cylB U ABC-2 type transporter
IEDFMFCO_00726 2.9e-36 K LytTr DNA-binding domain
IEDFMFCO_00727 9e-18 S Protein of unknown function (DUF3021)
IEDFMFCO_00728 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IEDFMFCO_00729 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IEDFMFCO_00730 4.6e-28
IEDFMFCO_00731 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEDFMFCO_00732 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
IEDFMFCO_00733 4.9e-57 XK27_04120 S Putative amino acid metabolism
IEDFMFCO_00734 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IEDFMFCO_00735 1.3e-241 ktrB P Potassium uptake protein
IEDFMFCO_00736 2.6e-115 ktrA P domain protein
IEDFMFCO_00737 2.3e-120 N WxL domain surface cell wall-binding
IEDFMFCO_00738 1.7e-193 S Bacterial protein of unknown function (DUF916)
IEDFMFCO_00739 1.4e-267 N domain, Protein
IEDFMFCO_00740 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IEDFMFCO_00741 3.6e-120 S Repeat protein
IEDFMFCO_00742 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IEDFMFCO_00743 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEDFMFCO_00744 4.1e-108 mltD CBM50 M NlpC P60 family protein
IEDFMFCO_00745 1.7e-28
IEDFMFCO_00746 5.7e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IEDFMFCO_00747 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEDFMFCO_00748 3.1e-33 ykzG S Belongs to the UPF0356 family
IEDFMFCO_00749 1.6e-85
IEDFMFCO_00750 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEDFMFCO_00751 8.9e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IEDFMFCO_00752 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IEDFMFCO_00753 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IEDFMFCO_00754 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
IEDFMFCO_00755 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
IEDFMFCO_00756 3.3e-46 yktA S Belongs to the UPF0223 family
IEDFMFCO_00757 6.3e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IEDFMFCO_00758 0.0 typA T GTP-binding protein TypA
IEDFMFCO_00759 1.1e-197
IEDFMFCO_00761 4.6e-163 K Transcriptional regulator
IEDFMFCO_00762 5.7e-163 akr5f 1.1.1.346 S reductase
IEDFMFCO_00763 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
IEDFMFCO_00764 3.9e-78 K Winged helix DNA-binding domain
IEDFMFCO_00765 2.2e-268 ycaM E amino acid
IEDFMFCO_00766 3.5e-127 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
IEDFMFCO_00767 2.7e-32
IEDFMFCO_00768 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
IEDFMFCO_00769 1.1e-58 M Bacterial Ig-like domain (group 3)
IEDFMFCO_00770 0.0 M Bacterial Ig-like domain (group 3)
IEDFMFCO_00771 1.1e-77 fld C Flavodoxin
IEDFMFCO_00772 4.5e-233
IEDFMFCO_00773 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IEDFMFCO_00774 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IEDFMFCO_00775 1.2e-150 EG EamA-like transporter family
IEDFMFCO_00776 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEDFMFCO_00777 9.8e-152 S hydrolase
IEDFMFCO_00778 1.8e-81
IEDFMFCO_00779 5.5e-121 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IEDFMFCO_00780 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
IEDFMFCO_00781 2e-129 gntR K UTRA
IEDFMFCO_00782 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IEDFMFCO_00783 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
IEDFMFCO_00784 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_00785 5.2e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_00786 1.1e-245 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IEDFMFCO_00787 1.4e-133 V AAA domain, putative AbiEii toxin, Type IV TA system
IEDFMFCO_00788 3.2e-154 V ABC transporter
IEDFMFCO_00789 1.3e-117 K Transcriptional regulator
IEDFMFCO_00790 2.3e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IEDFMFCO_00791 2.1e-88 niaR S 3H domain
IEDFMFCO_00792 5.2e-224 EGP Major facilitator Superfamily
IEDFMFCO_00793 1.8e-231 S Sterol carrier protein domain
IEDFMFCO_00794 5.5e-211 S Bacterial protein of unknown function (DUF871)
IEDFMFCO_00795 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
IEDFMFCO_00796 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
IEDFMFCO_00797 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
IEDFMFCO_00798 1.7e-102 3.6.1.13 L Belongs to the Nudix hydrolase family
IEDFMFCO_00799 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IEDFMFCO_00800 1.5e-11 mcbG S Pentapeptide repeats (8 copies)
IEDFMFCO_00801 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
IEDFMFCO_00802 3.6e-282 thrC 4.2.3.1 E Threonine synthase
IEDFMFCO_00803 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IEDFMFCO_00804 1.5e-52
IEDFMFCO_00805 5.4e-118
IEDFMFCO_00806 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
IEDFMFCO_00807 3.3e-233 malY 4.4.1.8 E Aminotransferase, class I
IEDFMFCO_00809 9.4e-50
IEDFMFCO_00810 1.1e-88
IEDFMFCO_00811 4.2e-71 gtcA S Teichoic acid glycosylation protein
IEDFMFCO_00812 1.2e-35
IEDFMFCO_00813 1.9e-80 uspA T universal stress protein
IEDFMFCO_00814 5.8e-149
IEDFMFCO_00815 6.9e-164 V ABC transporter, ATP-binding protein
IEDFMFCO_00816 7.9e-61 gntR1 K Transcriptional regulator, GntR family
IEDFMFCO_00817 8e-42
IEDFMFCO_00818 0.0 V FtsX-like permease family
IEDFMFCO_00819 1.7e-139 cysA V ABC transporter, ATP-binding protein
IEDFMFCO_00820 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
IEDFMFCO_00821 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
IEDFMFCO_00822 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
IEDFMFCO_00823 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
IEDFMFCO_00824 4.9e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
IEDFMFCO_00825 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
IEDFMFCO_00826 1.5e-223 XK27_09615 1.3.5.4 S reductase
IEDFMFCO_00827 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IEDFMFCO_00828 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IEDFMFCO_00829 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IEDFMFCO_00830 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEDFMFCO_00831 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEDFMFCO_00832 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEDFMFCO_00833 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IEDFMFCO_00834 7.7e-191 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IEDFMFCO_00835 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IEDFMFCO_00836 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IEDFMFCO_00837 4.2e-215 purD 6.3.4.13 F Belongs to the GARS family
IEDFMFCO_00838 3.9e-127 2.1.1.14 E Methionine synthase
IEDFMFCO_00839 7.8e-252 pgaC GT2 M Glycosyl transferase
IEDFMFCO_00840 4.4e-94
IEDFMFCO_00841 6.5e-156 T EAL domain
IEDFMFCO_00842 5.6e-161 GM NmrA-like family
IEDFMFCO_00843 2.4e-221 pbuG S Permease family
IEDFMFCO_00844 2.7e-236 pbuX F xanthine permease
IEDFMFCO_00845 1e-298 pucR QT Purine catabolism regulatory protein-like family
IEDFMFCO_00846 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IEDFMFCO_00847 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IEDFMFCO_00848 4.4e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IEDFMFCO_00849 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IEDFMFCO_00850 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IEDFMFCO_00851 9.7e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IEDFMFCO_00852 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IEDFMFCO_00853 1.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IEDFMFCO_00854 2.9e-171 ydcZ S Putative inner membrane exporter, YdcZ
IEDFMFCO_00855 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IEDFMFCO_00856 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IEDFMFCO_00857 1.3e-72
IEDFMFCO_00858 0.0 S Bacterial membrane protein YfhO
IEDFMFCO_00859 2.7e-91
IEDFMFCO_00860 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IEDFMFCO_00861 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IEDFMFCO_00862 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IEDFMFCO_00863 2.2e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IEDFMFCO_00864 2.8e-29 yajC U Preprotein translocase
IEDFMFCO_00865 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEDFMFCO_00866 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IEDFMFCO_00867 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IEDFMFCO_00868 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IEDFMFCO_00869 2.4e-43 yrzL S Belongs to the UPF0297 family
IEDFMFCO_00870 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IEDFMFCO_00871 1.6e-48 yrzB S Belongs to the UPF0473 family
IEDFMFCO_00872 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IEDFMFCO_00873 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IEDFMFCO_00874 3.3e-52 trxA O Belongs to the thioredoxin family
IEDFMFCO_00875 7.6e-126 yslB S Protein of unknown function (DUF2507)
IEDFMFCO_00876 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IEDFMFCO_00877 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IEDFMFCO_00878 1.2e-94 S Phosphoesterase
IEDFMFCO_00879 6.5e-87 ykuL S (CBS) domain
IEDFMFCO_00880 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IEDFMFCO_00881 1.1e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IEDFMFCO_00882 2.6e-158 ykuT M mechanosensitive ion channel
IEDFMFCO_00883 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IEDFMFCO_00884 2.8e-56
IEDFMFCO_00885 1.1e-80 K helix_turn_helix, mercury resistance
IEDFMFCO_00886 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IEDFMFCO_00887 1.9e-181 ccpA K catabolite control protein A
IEDFMFCO_00888 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IEDFMFCO_00889 1.6e-49 S DsrE/DsrF-like family
IEDFMFCO_00890 8.3e-131 yebC K Transcriptional regulatory protein
IEDFMFCO_00891 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEDFMFCO_00892 2.8e-174 comGA NU Type II IV secretion system protein
IEDFMFCO_00893 1.6e-188 comGB NU type II secretion system
IEDFMFCO_00894 5.5e-43 comGC U competence protein ComGC
IEDFMFCO_00895 3.2e-83 gspG NU general secretion pathway protein
IEDFMFCO_00896 6.6e-20
IEDFMFCO_00897 6.6e-37 S Prokaryotic N-terminal methylation motif
IEDFMFCO_00899 3.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
IEDFMFCO_00900 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEDFMFCO_00901 5.6e-253 cycA E Amino acid permease
IEDFMFCO_00902 4.4e-117 S Calcineurin-like phosphoesterase
IEDFMFCO_00903 8.7e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IEDFMFCO_00904 1.3e-79 yutD S Protein of unknown function (DUF1027)
IEDFMFCO_00905 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IEDFMFCO_00906 3.9e-116 S Protein of unknown function (DUF1461)
IEDFMFCO_00907 3e-119 dedA S SNARE-like domain protein
IEDFMFCO_00908 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IEDFMFCO_00909 1.6e-75 yugI 5.3.1.9 J general stress protein
IEDFMFCO_00910 3.5e-64
IEDFMFCO_00911 2e-106 3.2.2.20 K acetyltransferase
IEDFMFCO_00912 7.8e-296 S ABC transporter, ATP-binding protein
IEDFMFCO_00913 7.8e-219 2.7.7.65 T diguanylate cyclase
IEDFMFCO_00914 5.1e-34
IEDFMFCO_00915 2e-35
IEDFMFCO_00916 6.6e-81 K AsnC family
IEDFMFCO_00917 2.8e-173 ykfC 3.4.14.13 M NlpC/P60 family
IEDFMFCO_00918 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
IEDFMFCO_00920 3.8e-23
IEDFMFCO_00921 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
IEDFMFCO_00922 9.8e-214 yceI EGP Major facilitator Superfamily
IEDFMFCO_00923 8.6e-48
IEDFMFCO_00924 1.9e-90 S ECF-type riboflavin transporter, S component
IEDFMFCO_00925 4.1e-37 sip L Belongs to the 'phage' integrase family
IEDFMFCO_00926 3.1e-55 sip L Phage integrase, N-terminal SAM-like domain
IEDFMFCO_00929 5.1e-61 S Phage regulatory protein Rha (Phage_pRha)
IEDFMFCO_00930 1.3e-20
IEDFMFCO_00933 4.4e-127 S Virulence-associated protein E
IEDFMFCO_00934 6.8e-17
IEDFMFCO_00935 3.7e-09
IEDFMFCO_00940 1.5e-169 EG EamA-like transporter family
IEDFMFCO_00941 2.3e-38 gcvR T Belongs to the UPF0237 family
IEDFMFCO_00942 3e-243 XK27_08635 S UPF0210 protein
IEDFMFCO_00943 1.6e-134 K response regulator
IEDFMFCO_00944 2.9e-287 yclK 2.7.13.3 T Histidine kinase
IEDFMFCO_00945 2.7e-216 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
IEDFMFCO_00946 9.7e-155 glcU U sugar transport
IEDFMFCO_00947 1.1e-258 pgi 5.3.1.9 G Belongs to the GPI family
IEDFMFCO_00948 6.8e-24
IEDFMFCO_00949 0.0 macB3 V ABC transporter, ATP-binding protein
IEDFMFCO_00950 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IEDFMFCO_00951 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
IEDFMFCO_00952 1.6e-16
IEDFMFCO_00953 1.9e-18
IEDFMFCO_00954 5.2e-15
IEDFMFCO_00955 7.2e-17
IEDFMFCO_00956 2.7e-16
IEDFMFCO_00957 3.4e-310 M MucBP domain
IEDFMFCO_00958 0.0 bztC D nuclear chromosome segregation
IEDFMFCO_00959 7.3e-83 K MarR family
IEDFMFCO_00960 1.4e-43
IEDFMFCO_00961 2e-38
IEDFMFCO_00963 8.9e-30
IEDFMFCO_00965 5.6e-219 int L Belongs to the 'phage' integrase family
IEDFMFCO_00966 4.3e-40 S Domain of unknown function DUF1829
IEDFMFCO_00971 1.3e-11 M LysM domain
IEDFMFCO_00972 6.1e-13
IEDFMFCO_00975 8.5e-11 S DNA/RNA non-specific endonuclease
IEDFMFCO_00976 3.6e-09 S Pfam:Peptidase_M78
IEDFMFCO_00977 7.5e-22 S protein disulfide oxidoreductase activity
IEDFMFCO_00980 1.7e-37 K sequence-specific DNA binding
IEDFMFCO_00981 5.8e-26 K Cro/C1-type HTH DNA-binding domain
IEDFMFCO_00984 8.5e-53
IEDFMFCO_00985 3.1e-84
IEDFMFCO_00986 1.9e-14 S Domain of unknown function (DUF1508)
IEDFMFCO_00987 6.3e-69
IEDFMFCO_00988 2.1e-155 recT L RecT family
IEDFMFCO_00989 3.9e-137 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IEDFMFCO_00990 1.8e-146 3.1.3.16 L DnaD domain protein
IEDFMFCO_00991 7e-49
IEDFMFCO_00992 2.7e-94
IEDFMFCO_00993 6.2e-64
IEDFMFCO_00994 8.4e-66 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IEDFMFCO_00996 1.7e-81 arpU S Phage transcriptional regulator, ArpU family
IEDFMFCO_00999 2.1e-18 S KTSC domain
IEDFMFCO_01001 9.9e-13
IEDFMFCO_01002 6.4e-64 ps333 L Terminase small subunit
IEDFMFCO_01003 3.7e-240 ps334 S Terminase-like family
IEDFMFCO_01004 1.3e-266 S Phage portal protein, SPP1 Gp6-like
IEDFMFCO_01005 5.5e-37 J Cysteine protease Prp
IEDFMFCO_01006 4.7e-302 S Phage Mu protein F like protein
IEDFMFCO_01007 2.4e-30
IEDFMFCO_01009 2.7e-14 S Domain of unknown function (DUF4355)
IEDFMFCO_01010 2.6e-50
IEDFMFCO_01011 2e-175 S Phage major capsid protein E
IEDFMFCO_01013 4.6e-52
IEDFMFCO_01014 1.5e-50
IEDFMFCO_01015 1.3e-88
IEDFMFCO_01016 1.9e-54
IEDFMFCO_01017 6.9e-78 S Phage tail tube protein, TTP
IEDFMFCO_01018 6.3e-64
IEDFMFCO_01019 8e-23
IEDFMFCO_01020 0.0 D NLP P60 protein
IEDFMFCO_01021 5.9e-61
IEDFMFCO_01022 0.0 sidC GT2,GT4 LM DNA recombination
IEDFMFCO_01023 1.3e-206 sidC GT2,GT4 LM DNA recombination
IEDFMFCO_01024 1.6e-71 S Protein of unknown function (DUF1617)
IEDFMFCO_01026 2.7e-184 M hydrolase, family 25
IEDFMFCO_01027 4.4e-46
IEDFMFCO_01028 8.5e-34 hol S Bacteriophage holin
IEDFMFCO_01029 1.4e-79
IEDFMFCO_01032 3.8e-135 yxkH G Polysaccharide deacetylase
IEDFMFCO_01033 3.3e-65 S Protein of unknown function (DUF1093)
IEDFMFCO_01034 0.0 ycfI V ABC transporter, ATP-binding protein
IEDFMFCO_01035 0.0 yfiC V ABC transporter
IEDFMFCO_01036 5.3e-125
IEDFMFCO_01037 1.9e-58
IEDFMFCO_01038 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IEDFMFCO_01039 5.2e-29
IEDFMFCO_01040 1.4e-192 ampC V Beta-lactamase
IEDFMFCO_01041 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
IEDFMFCO_01042 2.2e-136 cobQ S glutamine amidotransferase
IEDFMFCO_01043 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IEDFMFCO_01044 9.3e-109 tdk 2.7.1.21 F thymidine kinase
IEDFMFCO_01045 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IEDFMFCO_01046 1e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IEDFMFCO_01047 6.9e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IEDFMFCO_01048 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IEDFMFCO_01049 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IEDFMFCO_01050 7e-40
IEDFMFCO_01052 8.6e-249 EGP Major facilitator Superfamily
IEDFMFCO_01053 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
IEDFMFCO_01054 4.7e-83 cvpA S Colicin V production protein
IEDFMFCO_01055 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IEDFMFCO_01056 6.3e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IEDFMFCO_01057 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IEDFMFCO_01058 4.8e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IEDFMFCO_01059 1.7e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IEDFMFCO_01060 1.2e-213 folP 2.5.1.15 H dihydropteroate synthase
IEDFMFCO_01061 6.5e-96 tag 3.2.2.20 L glycosylase
IEDFMFCO_01063 2.1e-21
IEDFMFCO_01065 1.4e-99 K Helix-turn-helix XRE-family like proteins
IEDFMFCO_01066 2.7e-160 czcD P cation diffusion facilitator family transporter
IEDFMFCO_01067 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
IEDFMFCO_01068 3e-116 hly S protein, hemolysin III
IEDFMFCO_01069 1.1e-44 qacH U Small Multidrug Resistance protein
IEDFMFCO_01070 4.4e-59 qacC P Small Multidrug Resistance protein
IEDFMFCO_01071 4e-217 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IEDFMFCO_01072 3.1e-179 K AI-2E family transporter
IEDFMFCO_01073 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEDFMFCO_01074 0.0 kup P Transport of potassium into the cell
IEDFMFCO_01076 1.5e-256 yhdG E C-terminus of AA_permease
IEDFMFCO_01077 6.2e-82
IEDFMFCO_01079 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEDFMFCO_01080 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
IEDFMFCO_01081 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IEDFMFCO_01082 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEDFMFCO_01083 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEDFMFCO_01084 4.9e-54 S Enterocin A Immunity
IEDFMFCO_01085 8.1e-257 gor 1.8.1.7 C Glutathione reductase
IEDFMFCO_01086 7.1e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IEDFMFCO_01087 1.7e-184 D Alpha beta
IEDFMFCO_01088 7.4e-166 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
IEDFMFCO_01089 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
IEDFMFCO_01090 3.5e-118 yugP S Putative neutral zinc metallopeptidase
IEDFMFCO_01091 4.1e-25
IEDFMFCO_01092 2.5e-145 DegV S EDD domain protein, DegV family
IEDFMFCO_01093 7.3e-127 lrgB M LrgB-like family
IEDFMFCO_01094 5.1e-64 lrgA S LrgA family
IEDFMFCO_01095 3.8e-104 J Acetyltransferase (GNAT) domain
IEDFMFCO_01096 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
IEDFMFCO_01097 5.4e-36 S Phospholipase_D-nuclease N-terminal
IEDFMFCO_01098 7.1e-59 S Enterocin A Immunity
IEDFMFCO_01099 9.8e-88 perR P Belongs to the Fur family
IEDFMFCO_01100 4.2e-104
IEDFMFCO_01101 7.9e-238 S module of peptide synthetase
IEDFMFCO_01102 2e-100 S NADPH-dependent FMN reductase
IEDFMFCO_01103 1.4e-08
IEDFMFCO_01104 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
IEDFMFCO_01105 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
IEDFMFCO_01106 2.6e-155 1.6.5.2 GM NmrA-like family
IEDFMFCO_01107 2e-77 merR K MerR family regulatory protein
IEDFMFCO_01108 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEDFMFCO_01109 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IEDFMFCO_01110 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IEDFMFCO_01111 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
IEDFMFCO_01112 2e-307 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
IEDFMFCO_01113 1.1e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IEDFMFCO_01114 9.4e-147 cof S haloacid dehalogenase-like hydrolase
IEDFMFCO_01115 6.5e-151 qorB 1.6.5.2 GM NmrA-like family
IEDFMFCO_01116 1.2e-76
IEDFMFCO_01117 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEDFMFCO_01118 9.4e-118 ybbL S ABC transporter, ATP-binding protein
IEDFMFCO_01119 2e-127 ybbM S Uncharacterised protein family (UPF0014)
IEDFMFCO_01120 1.3e-204 S DUF218 domain
IEDFMFCO_01121 3.2e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IEDFMFCO_01122 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IEDFMFCO_01123 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
IEDFMFCO_01124 5e-128 S Putative adhesin
IEDFMFCO_01125 5.1e-84 XK27_06920 S Protein of unknown function (DUF1700)
IEDFMFCO_01126 6.8e-53 K Transcriptional regulator
IEDFMFCO_01127 2.9e-78 KT response to antibiotic
IEDFMFCO_01128 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IEDFMFCO_01129 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IEDFMFCO_01130 8.1e-123 tcyB E ABC transporter
IEDFMFCO_01131 1.8e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IEDFMFCO_01132 2.7e-235 EK Aminotransferase, class I
IEDFMFCO_01133 2.1e-168 K LysR substrate binding domain
IEDFMFCO_01134 4.3e-147 S Alpha/beta hydrolase of unknown function (DUF915)
IEDFMFCO_01135 0.0 S Bacterial membrane protein YfhO
IEDFMFCO_01136 4.1e-226 nupG F Nucleoside
IEDFMFCO_01137 2.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IEDFMFCO_01138 2.7e-149 noc K Belongs to the ParB family
IEDFMFCO_01139 1.8e-136 soj D Sporulation initiation inhibitor
IEDFMFCO_01140 1.2e-155 spo0J K Belongs to the ParB family
IEDFMFCO_01141 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
IEDFMFCO_01142 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IEDFMFCO_01143 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
IEDFMFCO_01144 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IEDFMFCO_01145 2.9e-160 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IEDFMFCO_01146 5.5e-124 yoaK S Protein of unknown function (DUF1275)
IEDFMFCO_01147 3.2e-124 K response regulator
IEDFMFCO_01148 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
IEDFMFCO_01149 2.4e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IEDFMFCO_01150 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IEDFMFCO_01151 5.1e-131 azlC E branched-chain amino acid
IEDFMFCO_01152 2.3e-54 azlD S branched-chain amino acid
IEDFMFCO_01153 1.6e-110 S membrane transporter protein
IEDFMFCO_01154 4.8e-55
IEDFMFCO_01155 3.9e-75 S Psort location Cytoplasmic, score
IEDFMFCO_01156 6e-97 S Domain of unknown function (DUF4352)
IEDFMFCO_01157 6.8e-25 S Protein of unknown function (DUF4064)
IEDFMFCO_01158 2e-202 KLT Protein tyrosine kinase
IEDFMFCO_01159 3.6e-163
IEDFMFCO_01160 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IEDFMFCO_01161 7.8e-82
IEDFMFCO_01162 8.3e-210 xylR GK ROK family
IEDFMFCO_01163 1.9e-171 K AI-2E family transporter
IEDFMFCO_01164 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEDFMFCO_01165 8.8e-40
IEDFMFCO_01167 6.8e-33 L transposase activity
IEDFMFCO_01169 2.4e-104 K Bacterial regulatory proteins, tetR family
IEDFMFCO_01170 9.2e-65 S Domain of unknown function (DUF4440)
IEDFMFCO_01171 7.2e-259 qacA EGP Fungal trichothecene efflux pump (TRI12)
IEDFMFCO_01172 3.2e-77 3.5.4.1 GM SnoaL-like domain
IEDFMFCO_01173 3.7e-108 GM NAD(P)H-binding
IEDFMFCO_01174 5.9e-112 akr5f 1.1.1.346 S reductase
IEDFMFCO_01175 1.1e-100 M ErfK YbiS YcfS YnhG
IEDFMFCO_01176 2.5e-36 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IEDFMFCO_01177 3.8e-204 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IEDFMFCO_01178 2.3e-51 K Helix-turn-helix domain
IEDFMFCO_01179 1.3e-64 V ABC transporter
IEDFMFCO_01180 1.9e-66
IEDFMFCO_01181 8.3e-41 K HxlR-like helix-turn-helix
IEDFMFCO_01182 4e-107 ydeA S intracellular protease amidase
IEDFMFCO_01183 1.9e-43 S Protein of unknown function (DUF3781)
IEDFMFCO_01184 5.6e-207 S Membrane
IEDFMFCO_01185 7.6e-64 S Protein of unknown function (DUF1093)
IEDFMFCO_01186 1.3e-23 rmeD K helix_turn_helix, mercury resistance
IEDFMFCO_01187 1e-29 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
IEDFMFCO_01188 1.5e-11
IEDFMFCO_01189 4.1e-65
IEDFMFCO_01190 1.6e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_01191 4.4e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_01192 2.2e-115 K UTRA
IEDFMFCO_01193 1.7e-84 dps P Belongs to the Dps family
IEDFMFCO_01194 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
IEDFMFCO_01195 8.6e-284 1.3.5.4 C FAD binding domain
IEDFMFCO_01196 8.7e-162 K LysR substrate binding domain
IEDFMFCO_01197 1.5e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
IEDFMFCO_01198 3.5e-291 yjcE P Sodium proton antiporter
IEDFMFCO_01199 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEDFMFCO_01200 2e-115 K Bacterial regulatory proteins, tetR family
IEDFMFCO_01201 1.7e-179 NU Mycoplasma protein of unknown function, DUF285
IEDFMFCO_01202 8.7e-83 S WxL domain surface cell wall-binding
IEDFMFCO_01203 6.8e-174 S Bacterial protein of unknown function (DUF916)
IEDFMFCO_01204 2e-39 pelX UW LPXTG-motif cell wall anchor domain protein
IEDFMFCO_01205 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
IEDFMFCO_01206 1.6e-64 K helix_turn_helix, mercury resistance
IEDFMFCO_01207 7.5e-152 IQ Enoyl-(Acyl carrier protein) reductase
IEDFMFCO_01208 1.3e-68 maa S transferase hexapeptide repeat
IEDFMFCO_01209 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFMFCO_01210 4.1e-164 GM NmrA-like family
IEDFMFCO_01211 5.4e-92 K Bacterial regulatory proteins, tetR family
IEDFMFCO_01212 7.8e-172 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFMFCO_01213 2.1e-177 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFMFCO_01214 1.1e-144 fhuC 3.6.3.34 HP ABC transporter
IEDFMFCO_01215 1.2e-169 fhuD P Periplasmic binding protein
IEDFMFCO_01216 4.3e-109 K Bacterial regulatory proteins, tetR family
IEDFMFCO_01217 6e-253 yfjF U Sugar (and other) transporter
IEDFMFCO_01220 1.5e-180 S Aldo keto reductase
IEDFMFCO_01221 4.1e-101 S Protein of unknown function (DUF1211)
IEDFMFCO_01222 1.2e-191 1.1.1.219 GM Male sterility protein
IEDFMFCO_01223 3.2e-98 K Bacterial regulatory proteins, tetR family
IEDFMFCO_01224 9.8e-132 ydfG S KR domain
IEDFMFCO_01225 3.7e-63 hxlR K HxlR-like helix-turn-helix
IEDFMFCO_01226 1e-47 S Domain of unknown function (DUF1905)
IEDFMFCO_01227 0.0 M Glycosyl hydrolases family 25
IEDFMFCO_01228 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IEDFMFCO_01229 1.1e-167 GM NmrA-like family
IEDFMFCO_01230 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
IEDFMFCO_01232 3e-205 2.7.13.3 T GHKL domain
IEDFMFCO_01233 5.7e-135 K LytTr DNA-binding domain
IEDFMFCO_01234 0.0 asnB 6.3.5.4 E Asparagine synthase
IEDFMFCO_01235 1.6e-93 M ErfK YbiS YcfS YnhG
IEDFMFCO_01236 4.9e-213 ytbD EGP Major facilitator Superfamily
IEDFMFCO_01237 2e-61 K Transcriptional regulator, HxlR family
IEDFMFCO_01238 3e-116 S Haloacid dehalogenase-like hydrolase
IEDFMFCO_01239 2.3e-116
IEDFMFCO_01240 6.7e-213 NU Mycoplasma protein of unknown function, DUF285
IEDFMFCO_01241 1.1e-62
IEDFMFCO_01242 7.5e-101 S WxL domain surface cell wall-binding
IEDFMFCO_01243 1.4e-187 S Cell surface protein
IEDFMFCO_01244 2.5e-115 S GyrI-like small molecule binding domain
IEDFMFCO_01245 1.9e-68 S Iron-sulphur cluster biosynthesis
IEDFMFCO_01246 3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
IEDFMFCO_01247 1.7e-101 S WxL domain surface cell wall-binding
IEDFMFCO_01248 9.2e-187 S Cell surface protein
IEDFMFCO_01249 3.4e-51
IEDFMFCO_01250 4.2e-262
IEDFMFCO_01251 3.5e-228 hpk9 2.7.13.3 T GHKL domain
IEDFMFCO_01252 2.9e-38 S TfoX C-terminal domain
IEDFMFCO_01253 6e-140 K Helix-turn-helix domain
IEDFMFCO_01254 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IEDFMFCO_01255 2.6e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IEDFMFCO_01256 6.4e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IEDFMFCO_01257 0.0 ctpA 3.6.3.54 P P-type ATPase
IEDFMFCO_01258 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
IEDFMFCO_01259 2.3e-195 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IEDFMFCO_01260 3.9e-66 lysM M LysM domain
IEDFMFCO_01261 2.8e-266 yjeM E Amino Acid
IEDFMFCO_01262 1.5e-144 K Helix-turn-helix XRE-family like proteins
IEDFMFCO_01263 1.4e-69
IEDFMFCO_01265 5e-162 IQ KR domain
IEDFMFCO_01266 1.3e-229 amd 3.5.1.47 E Peptidase family M20/M25/M40
IEDFMFCO_01267 9.1e-177 O protein import
IEDFMFCO_01268 4.8e-311 XK27_09600 V ABC transporter, ATP-binding protein
IEDFMFCO_01269 0.0 V ABC transporter
IEDFMFCO_01270 8.6e-218 ykiI
IEDFMFCO_01271 3.6e-117 GM NAD(P)H-binding
IEDFMFCO_01272 2.5e-138 IQ reductase
IEDFMFCO_01273 2.4e-59 I sulfurtransferase activity
IEDFMFCO_01274 2.3e-77 yphH S Cupin domain
IEDFMFCO_01275 2.6e-91 S Phosphatidylethanolamine-binding protein
IEDFMFCO_01276 3e-116 GM NAD(P)H-binding
IEDFMFCO_01277 1.3e-175 C C4-dicarboxylate transmembrane transporter activity
IEDFMFCO_01278 1.4e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFMFCO_01279 6e-73
IEDFMFCO_01280 2.6e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
IEDFMFCO_01281 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IEDFMFCO_01282 1.2e-73 S Psort location Cytoplasmic, score
IEDFMFCO_01283 3.3e-219 T diguanylate cyclase
IEDFMFCO_01284 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
IEDFMFCO_01285 4.2e-92
IEDFMFCO_01286 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
IEDFMFCO_01287 1.8e-54 nudA S ASCH
IEDFMFCO_01288 4.7e-108 S SdpI/YhfL protein family
IEDFMFCO_01289 2.3e-95 M Lysin motif
IEDFMFCO_01290 2.3e-65 M LysM domain
IEDFMFCO_01291 2.7e-76 K helix_turn_helix, mercury resistance
IEDFMFCO_01292 1.8e-184 1.1.1.219 GM Male sterility protein
IEDFMFCO_01293 3.1e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_01294 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_01295 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IEDFMFCO_01296 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IEDFMFCO_01297 2e-149 dicA K Helix-turn-helix domain
IEDFMFCO_01298 3.6e-54
IEDFMFCO_01299 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
IEDFMFCO_01300 7.4e-64
IEDFMFCO_01301 0.0 P Concanavalin A-like lectin/glucanases superfamily
IEDFMFCO_01302 0.0 yhcA V ABC transporter, ATP-binding protein
IEDFMFCO_01303 1.9e-113
IEDFMFCO_01304 4.1e-59
IEDFMFCO_01305 1.8e-279 lldP C L-lactate permease
IEDFMFCO_01306 3.3e-226
IEDFMFCO_01307 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IEDFMFCO_01308 1e-190 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IEDFMFCO_01309 9.5e-195 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IEDFMFCO_01310 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IEDFMFCO_01311 2.1e-91 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IEDFMFCO_01312 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
IEDFMFCO_01313 1.2e-239 gshR1 1.8.1.7 C Glutathione reductase
IEDFMFCO_01314 2.1e-51
IEDFMFCO_01315 1.8e-245 M Glycosyl transferase family group 2
IEDFMFCO_01316 7.5e-275 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IEDFMFCO_01317 1.4e-156 xerD L Phage integrase, N-terminal SAM-like domain
IEDFMFCO_01318 4.2e-32 S YozE SAM-like fold
IEDFMFCO_01319 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IEDFMFCO_01320 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IEDFMFCO_01321 6.4e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
IEDFMFCO_01322 1.3e-176 K Transcriptional regulator
IEDFMFCO_01323 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEDFMFCO_01324 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEDFMFCO_01325 5.7e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IEDFMFCO_01326 2.2e-170 lacX 5.1.3.3 G Aldose 1-epimerase
IEDFMFCO_01327 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IEDFMFCO_01328 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IEDFMFCO_01329 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
IEDFMFCO_01330 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IEDFMFCO_01331 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEDFMFCO_01332 8e-157 dprA LU DNA protecting protein DprA
IEDFMFCO_01333 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEDFMFCO_01334 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IEDFMFCO_01335 1.4e-228 XK27_05470 E Methionine synthase
IEDFMFCO_01336 8.9e-170 cpsY K Transcriptional regulator, LysR family
IEDFMFCO_01337 6.5e-125 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IEDFMFCO_01338 7.4e-197 XK27_00915 C Luciferase-like monooxygenase
IEDFMFCO_01339 3.3e-251 emrY EGP Major facilitator Superfamily
IEDFMFCO_01340 1e-232 pyrP F Permease
IEDFMFCO_01341 5.5e-103 atpB C it plays a direct role in the translocation of protons across the membrane
IEDFMFCO_01342 1.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEDFMFCO_01343 1.6e-40 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IEDFMFCO_01344 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEDFMFCO_01345 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IEDFMFCO_01346 3.9e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IEDFMFCO_01347 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IEDFMFCO_01348 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IEDFMFCO_01349 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEDFMFCO_01350 2.1e-102 J Acetyltransferase (GNAT) domain
IEDFMFCO_01351 2.7e-180 mbl D Cell shape determining protein MreB Mrl
IEDFMFCO_01352 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IEDFMFCO_01353 3.3e-33 S Protein of unknown function (DUF2969)
IEDFMFCO_01354 9.3e-220 rodA D Belongs to the SEDS family
IEDFMFCO_01355 3.6e-48 gcsH2 E glycine cleavage
IEDFMFCO_01356 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEDFMFCO_01357 1.4e-111 metI U ABC transporter permease
IEDFMFCO_01358 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
IEDFMFCO_01359 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
IEDFMFCO_01360 3.5e-177 S Protein of unknown function (DUF2785)
IEDFMFCO_01361 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IEDFMFCO_01362 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IEDFMFCO_01363 5.1e-295 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IEDFMFCO_01364 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IEDFMFCO_01365 1e-199 bla2 3.5.2.6 V Beta-lactamase enzyme family
IEDFMFCO_01366 6.2e-82 usp6 T universal stress protein
IEDFMFCO_01367 1.5e-38
IEDFMFCO_01368 1.8e-237 rarA L recombination factor protein RarA
IEDFMFCO_01369 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IEDFMFCO_01370 5.9e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IEDFMFCO_01371 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
IEDFMFCO_01372 3.6e-103 G PTS system sorbose-specific iic component
IEDFMFCO_01373 2.7e-104 G PTS system mannose fructose sorbose family IID component
IEDFMFCO_01374 3.5e-41 2.7.1.191 G PTS system fructose IIA component
IEDFMFCO_01375 5.1e-232 malL 3.2.1.10 GH13 G COG0366 Glycosidases
IEDFMFCO_01376 8.6e-44 czrA K Helix-turn-helix domain
IEDFMFCO_01377 3.1e-110 S Protein of unknown function (DUF1648)
IEDFMFCO_01378 3.3e-80 yueI S Protein of unknown function (DUF1694)
IEDFMFCO_01379 2.6e-112 yktB S Belongs to the UPF0637 family
IEDFMFCO_01380 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IEDFMFCO_01381 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
IEDFMFCO_01382 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IEDFMFCO_01383 1.7e-218 iscS2 2.8.1.7 E Aminotransferase class V
IEDFMFCO_01384 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEDFMFCO_01385 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IEDFMFCO_01386 3.7e-205 yacL S domain protein
IEDFMFCO_01387 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEDFMFCO_01388 2e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEDFMFCO_01389 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IEDFMFCO_01390 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEDFMFCO_01391 5.3e-98 yacP S YacP-like NYN domain
IEDFMFCO_01392 2.4e-101 sigH K Sigma-70 region 2
IEDFMFCO_01393 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IEDFMFCO_01394 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IEDFMFCO_01395 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
IEDFMFCO_01396 1.1e-158 S Alpha/beta hydrolase of unknown function (DUF915)
IEDFMFCO_01397 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IEDFMFCO_01398 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IEDFMFCO_01399 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IEDFMFCO_01400 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IEDFMFCO_01401 2.7e-177 F DNA/RNA non-specific endonuclease
IEDFMFCO_01402 1.5e-38 L nuclease
IEDFMFCO_01403 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IEDFMFCO_01404 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
IEDFMFCO_01405 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEDFMFCO_01406 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEDFMFCO_01407 6.5e-37 nrdH O Glutaredoxin
IEDFMFCO_01408 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
IEDFMFCO_01409 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IEDFMFCO_01410 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEDFMFCO_01411 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IEDFMFCO_01412 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IEDFMFCO_01413 2.2e-38 yaaL S Protein of unknown function (DUF2508)
IEDFMFCO_01414 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IEDFMFCO_01415 2.4e-53 yaaQ S Cyclic-di-AMP receptor
IEDFMFCO_01416 9.7e-186 holB 2.7.7.7 L DNA polymerase III
IEDFMFCO_01417 1e-57 yabA L Involved in initiation control of chromosome replication
IEDFMFCO_01418 5.4e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IEDFMFCO_01419 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
IEDFMFCO_01420 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IEDFMFCO_01421 6.1e-210 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
IEDFMFCO_01422 6.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
IEDFMFCO_01423 7.7e-144 phnE1 3.6.1.63 U ABC transporter permease
IEDFMFCO_01424 2.3e-137 phnE 3.6.1.63 U Phosphonate ABC transporter permease
IEDFMFCO_01425 9.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IEDFMFCO_01426 1.9e-189 phnD P Phosphonate ABC transporter
IEDFMFCO_01427 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IEDFMFCO_01428 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IEDFMFCO_01429 3.8e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IEDFMFCO_01430 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IEDFMFCO_01431 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IEDFMFCO_01432 3.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEDFMFCO_01433 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IEDFMFCO_01434 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEDFMFCO_01435 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IEDFMFCO_01436 1.1e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IEDFMFCO_01437 3.1e-74 yabR J RNA binding
IEDFMFCO_01438 1.1e-63 divIC D Septum formation initiator
IEDFMFCO_01440 2.2e-42 yabO J S4 domain protein
IEDFMFCO_01441 2.1e-288 yabM S Polysaccharide biosynthesis protein
IEDFMFCO_01442 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEDFMFCO_01443 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IEDFMFCO_01444 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IEDFMFCO_01445 1.4e-264 S Putative peptidoglycan binding domain
IEDFMFCO_01446 2.1e-114 S (CBS) domain
IEDFMFCO_01447 2.1e-123 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
IEDFMFCO_01448 3.1e-170 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
IEDFMFCO_01449 1.2e-83 S QueT transporter
IEDFMFCO_01450 3.6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IEDFMFCO_01451 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
IEDFMFCO_01452 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IEDFMFCO_01453 2.6e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IEDFMFCO_01454 7.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IEDFMFCO_01455 1.7e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IEDFMFCO_01456 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IEDFMFCO_01457 5e-134 P ATPases associated with a variety of cellular activities
IEDFMFCO_01458 9.8e-130 ssuC2 U Binding-protein-dependent transport system inner membrane component
IEDFMFCO_01459 2.9e-193 P ABC transporter, substratebinding protein
IEDFMFCO_01460 0.0 kup P Transport of potassium into the cell
IEDFMFCO_01461 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
IEDFMFCO_01462 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEDFMFCO_01463 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IEDFMFCO_01464 9.6e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IEDFMFCO_01465 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IEDFMFCO_01466 1.7e-165 fabK 1.3.1.9 S Nitronate monooxygenase
IEDFMFCO_01467 0.0 helD 3.6.4.12 L DNA helicase
IEDFMFCO_01468 1.8e-108 dedA S SNARE associated Golgi protein
IEDFMFCO_01469 8.7e-300 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_01470 0.0 2.7.1.193, 2.7.1.211 G phosphotransferase system
IEDFMFCO_01471 1.9e-158 bglG3 K CAT RNA binding domain
IEDFMFCO_01472 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
IEDFMFCO_01473 0.0 yjbQ P TrkA C-terminal domain protein
IEDFMFCO_01474 4.7e-125 pgm3 G Phosphoglycerate mutase family
IEDFMFCO_01475 3e-127 pgm3 G Phosphoglycerate mutase family
IEDFMFCO_01476 1.2e-26
IEDFMFCO_01477 1.3e-48 sugE U Multidrug resistance protein
IEDFMFCO_01478 9.9e-79 3.6.1.55 F NUDIX domain
IEDFMFCO_01479 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEDFMFCO_01480 7.1e-98 K Bacterial regulatory proteins, tetR family
IEDFMFCO_01481 3.8e-85 S membrane transporter protein
IEDFMFCO_01482 2.4e-209 EGP Major facilitator Superfamily
IEDFMFCO_01483 2e-71 K MarR family
IEDFMFCO_01484 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
IEDFMFCO_01485 4.8e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
IEDFMFCO_01486 2.1e-244 steT E amino acid
IEDFMFCO_01487 8.4e-142 G YdjC-like protein
IEDFMFCO_01488 1.8e-257 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
IEDFMFCO_01489 4.7e-154 K CAT RNA binding domain
IEDFMFCO_01490 1e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IEDFMFCO_01491 4e-108 glnP P ABC transporter permease
IEDFMFCO_01492 1.6e-109 gluC P ABC transporter permease
IEDFMFCO_01493 7.8e-149 glnH ET ABC transporter substrate-binding protein
IEDFMFCO_01494 7.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IEDFMFCO_01496 2e-39
IEDFMFCO_01497 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEDFMFCO_01498 3e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IEDFMFCO_01499 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IEDFMFCO_01500 4.9e-148
IEDFMFCO_01501 7.1e-12 3.2.1.14 GH18
IEDFMFCO_01502 1.3e-81 zur P Belongs to the Fur family
IEDFMFCO_01503 3.1e-104 gmk2 2.7.4.8 F Guanylate kinase
IEDFMFCO_01504 1.8e-19
IEDFMFCO_01505 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IEDFMFCO_01506 1.9e-147 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IEDFMFCO_01507 2.5e-88
IEDFMFCO_01508 8.2e-252 yfnA E Amino Acid
IEDFMFCO_01509 5.8e-46
IEDFMFCO_01510 5e-69 O OsmC-like protein
IEDFMFCO_01511 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IEDFMFCO_01512 0.0 oatA I Acyltransferase
IEDFMFCO_01513 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IEDFMFCO_01514 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IEDFMFCO_01515 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IEDFMFCO_01516 7.8e-91 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IEDFMFCO_01517 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IEDFMFCO_01518 1.2e-225 pbuG S permease
IEDFMFCO_01519 1.5e-19
IEDFMFCO_01520 1.3e-82 K Transcriptional regulator
IEDFMFCO_01521 5e-153 licD M LicD family
IEDFMFCO_01522 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IEDFMFCO_01523 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IEDFMFCO_01524 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IEDFMFCO_01525 1.4e-28 EGP Major facilitator Superfamily
IEDFMFCO_01526 3.1e-174 EGP Major facilitator Superfamily
IEDFMFCO_01527 1.1e-89 V VanZ like family
IEDFMFCO_01528 1.5e-33
IEDFMFCO_01529 1.9e-71 spxA 1.20.4.1 P ArsC family
IEDFMFCO_01531 8.6e-142
IEDFMFCO_01532 2.8e-298 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IEDFMFCO_01533 2.3e-96 liaI S membrane
IEDFMFCO_01534 4e-75 XK27_02470 K LytTr DNA-binding domain
IEDFMFCO_01535 1.5e-54 yneR S Belongs to the HesB IscA family
IEDFMFCO_01536 0.0 S membrane
IEDFMFCO_01537 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IEDFMFCO_01538 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IEDFMFCO_01539 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IEDFMFCO_01540 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
IEDFMFCO_01541 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
IEDFMFCO_01542 5.7e-180 glk 2.7.1.2 G Glucokinase
IEDFMFCO_01543 1.4e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
IEDFMFCO_01544 1.7e-67 yqhL P Rhodanese-like protein
IEDFMFCO_01545 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
IEDFMFCO_01546 1.1e-138 glpQ 3.1.4.46 C phosphodiesterase
IEDFMFCO_01547 1.2e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IEDFMFCO_01548 4.6e-64 glnR K Transcriptional regulator
IEDFMFCO_01549 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
IEDFMFCO_01550 5.5e-161
IEDFMFCO_01551 4e-181
IEDFMFCO_01552 6.2e-99 dut S Protein conserved in bacteria
IEDFMFCO_01553 1.8e-56
IEDFMFCO_01554 1.7e-30
IEDFMFCO_01557 5.4e-19
IEDFMFCO_01558 1.8e-89 K Transcriptional regulator
IEDFMFCO_01559 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IEDFMFCO_01560 3.2e-53 ysxB J Cysteine protease Prp
IEDFMFCO_01561 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IEDFMFCO_01562 1.6e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IEDFMFCO_01563 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEDFMFCO_01564 3.5e-74 yqhY S Asp23 family, cell envelope-related function
IEDFMFCO_01565 5.8e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IEDFMFCO_01566 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IEDFMFCO_01567 1.6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEDFMFCO_01568 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEDFMFCO_01569 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IEDFMFCO_01570 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IEDFMFCO_01571 7.4e-77 argR K Regulates arginine biosynthesis genes
IEDFMFCO_01572 6.3e-307 recN L May be involved in recombinational repair of damaged DNA
IEDFMFCO_01573 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
IEDFMFCO_01574 1.2e-104 opuCB E ABC transporter permease
IEDFMFCO_01575 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IEDFMFCO_01576 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
IEDFMFCO_01577 1.7e-54
IEDFMFCO_01579 1.4e-50
IEDFMFCO_01580 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IEDFMFCO_01581 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IEDFMFCO_01582 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEDFMFCO_01583 2.6e-39 ylqC S Belongs to the UPF0109 family
IEDFMFCO_01584 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IEDFMFCO_01585 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEDFMFCO_01586 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IEDFMFCO_01587 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IEDFMFCO_01588 0.0 smc D Required for chromosome condensation and partitioning
IEDFMFCO_01589 8.2e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IEDFMFCO_01590 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEDFMFCO_01591 6.7e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IEDFMFCO_01592 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IEDFMFCO_01593 0.0 yloV S DAK2 domain fusion protein YloV
IEDFMFCO_01594 1.8e-57 asp S Asp23 family, cell envelope-related function
IEDFMFCO_01595 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IEDFMFCO_01596 5.8e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
IEDFMFCO_01597 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IEDFMFCO_01598 1.6e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IEDFMFCO_01599 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IEDFMFCO_01600 1.7e-134 stp 3.1.3.16 T phosphatase
IEDFMFCO_01601 1.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IEDFMFCO_01602 4.2e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IEDFMFCO_01603 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEDFMFCO_01604 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEDFMFCO_01605 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IEDFMFCO_01606 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IEDFMFCO_01607 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IEDFMFCO_01608 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IEDFMFCO_01609 1.6e-46 ylxQ J ribosomal protein
IEDFMFCO_01610 9.5e-49 ylxR K Protein of unknown function (DUF448)
IEDFMFCO_01611 3.3e-217 nusA K Participates in both transcription termination and antitermination
IEDFMFCO_01612 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
IEDFMFCO_01613 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEDFMFCO_01614 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IEDFMFCO_01615 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IEDFMFCO_01616 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
IEDFMFCO_01617 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEDFMFCO_01618 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IEDFMFCO_01619 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IEDFMFCO_01620 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IEDFMFCO_01621 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
IEDFMFCO_01622 4.7e-134 S Haloacid dehalogenase-like hydrolase
IEDFMFCO_01623 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEDFMFCO_01624 2e-49 yazA L GIY-YIG catalytic domain protein
IEDFMFCO_01625 1.4e-136 yabB 2.1.1.223 L Methyltransferase small domain
IEDFMFCO_01626 6.4e-119 plsC 2.3.1.51 I Acyltransferase
IEDFMFCO_01627 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
IEDFMFCO_01628 2.9e-36 ynzC S UPF0291 protein
IEDFMFCO_01629 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEDFMFCO_01630 3.7e-87
IEDFMFCO_01631 3.9e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IEDFMFCO_01632 1.1e-76
IEDFMFCO_01633 1.3e-66
IEDFMFCO_01634 3.4e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
IEDFMFCO_01635 2.1e-100 L Helix-turn-helix domain
IEDFMFCO_01636 5.2e-59 lytR5 K Cell envelope-related transcriptional attenuator domain
IEDFMFCO_01637 3.2e-138 lytR5 K Cell envelope-related transcriptional attenuator domain
IEDFMFCO_01638 7.9e-143 P ATPases associated with a variety of cellular activities
IEDFMFCO_01639 7.6e-205 opuAB P Binding-protein-dependent transport system inner membrane component
IEDFMFCO_01640 1.2e-95 cadD P Cadmium resistance transporter
IEDFMFCO_01641 2e-49 K Transcriptional regulator, ArsR family
IEDFMFCO_01642 1.9e-116 S SNARE associated Golgi protein
IEDFMFCO_01643 4e-46
IEDFMFCO_01644 6.8e-72 T Belongs to the universal stress protein A family
IEDFMFCO_01645 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
IEDFMFCO_01646 7.9e-122 K Helix-turn-helix XRE-family like proteins
IEDFMFCO_01647 2.8e-82 gtrA S GtrA-like protein
IEDFMFCO_01648 1.7e-113 zmp3 O Zinc-dependent metalloprotease
IEDFMFCO_01649 7e-33
IEDFMFCO_01651 5.4e-212 livJ E Receptor family ligand binding region
IEDFMFCO_01652 6.5e-154 livH U Branched-chain amino acid transport system / permease component
IEDFMFCO_01653 4.5e-140 livM E Branched-chain amino acid transport system / permease component
IEDFMFCO_01654 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
IEDFMFCO_01655 9.5e-124 livF E ABC transporter
IEDFMFCO_01656 2.4e-97 acuB S Domain in cystathionine beta-synthase and other proteins.
IEDFMFCO_01657 1e-91 S WxL domain surface cell wall-binding
IEDFMFCO_01658 8.1e-188 S Cell surface protein
IEDFMFCO_01659 8.6e-63
IEDFMFCO_01660 2.3e-260
IEDFMFCO_01661 3.5e-169 XK27_00670 S ABC transporter
IEDFMFCO_01662 8.1e-153 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
IEDFMFCO_01663 8.1e-109 cmpC S ATPases associated with a variety of cellular activities
IEDFMFCO_01664 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
IEDFMFCO_01665 5e-119 drgA C Nitroreductase family
IEDFMFCO_01666 2.9e-96 rmaB K Transcriptional regulator, MarR family
IEDFMFCO_01667 0.0 lmrA 3.6.3.44 V ABC transporter
IEDFMFCO_01668 1.2e-160 ypbG 2.7.1.2 GK ROK family
IEDFMFCO_01669 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
IEDFMFCO_01670 2.1e-111 K Transcriptional regulator C-terminal region
IEDFMFCO_01671 1.1e-177 4.1.1.52 S Amidohydrolase
IEDFMFCO_01672 4.4e-129 E lipolytic protein G-D-S-L family
IEDFMFCO_01673 1.1e-159 yicL EG EamA-like transporter family
IEDFMFCO_01674 8.7e-174 sdrF M Collagen binding domain
IEDFMFCO_01675 5.6e-52 sdrF M Collagen binding domain
IEDFMFCO_01676 9.7e-269 I acetylesterase activity
IEDFMFCO_01677 5.2e-177 S Phosphotransferase system, EIIC
IEDFMFCO_01678 8.2e-134 aroD S Alpha/beta hydrolase family
IEDFMFCO_01679 3.2e-37
IEDFMFCO_01681 9.1e-133 S zinc-ribbon domain
IEDFMFCO_01682 7.4e-264 S response to antibiotic
IEDFMFCO_01683 9.3e-245 cycA E Amino acid permease
IEDFMFCO_01684 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
IEDFMFCO_01685 5.2e-129 yejC S Protein of unknown function (DUF1003)
IEDFMFCO_01686 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
IEDFMFCO_01687 4.6e-12
IEDFMFCO_01688 2.5e-209 pmrB EGP Major facilitator Superfamily
IEDFMFCO_01689 1.4e-147 2.7.7.12 C Domain of unknown function (DUF4931)
IEDFMFCO_01690 1.6e-48
IEDFMFCO_01691 4.3e-10
IEDFMFCO_01692 3.4e-132 S Protein of unknown function (DUF975)
IEDFMFCO_01693 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IEDFMFCO_01694 7e-161 degV S EDD domain protein, DegV family
IEDFMFCO_01695 1.9e-66 K Transcriptional regulator
IEDFMFCO_01696 0.0 FbpA K Fibronectin-binding protein
IEDFMFCO_01697 3.5e-132 S ABC-2 family transporter protein
IEDFMFCO_01698 1.3e-162 V ABC transporter, ATP-binding protein
IEDFMFCO_01699 9.7e-91 3.6.1.55 F NUDIX domain
IEDFMFCO_01700 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
IEDFMFCO_01701 1.2e-69 S LuxR family transcriptional regulator
IEDFMFCO_01702 1.7e-130 cat 2.3.1.28 V Chloramphenicol acetyltransferase
IEDFMFCO_01705 3.1e-71 frataxin S Domain of unknown function (DU1801)
IEDFMFCO_01706 6.4e-113 pgm5 G Phosphoglycerate mutase family
IEDFMFCO_01707 8.8e-288 S Bacterial membrane protein, YfhO
IEDFMFCO_01708 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IEDFMFCO_01709 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
IEDFMFCO_01710 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IEDFMFCO_01711 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IEDFMFCO_01712 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IEDFMFCO_01713 9.2e-295 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IEDFMFCO_01714 3.3e-62 esbA S Family of unknown function (DUF5322)
IEDFMFCO_01715 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
IEDFMFCO_01716 1.1e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
IEDFMFCO_01717 4.5e-146 S hydrolase activity, acting on ester bonds
IEDFMFCO_01718 3.5e-194
IEDFMFCO_01719 6.6e-122 3.6.3.35 P ATPases associated with a variety of cellular activities
IEDFMFCO_01720 1.9e-122
IEDFMFCO_01721 1.6e-182 mccF 3.4.17.13 V LD-carboxypeptidase
IEDFMFCO_01722 1.5e-239 M hydrolase, family 25
IEDFMFCO_01723 1.4e-78 K Acetyltransferase (GNAT) domain
IEDFMFCO_01724 2.5e-208 mccF V LD-carboxypeptidase
IEDFMFCO_01725 2.4e-200 M Glycosyltransferase, group 2 family protein
IEDFMFCO_01726 4.4e-73 S SnoaL-like domain
IEDFMFCO_01727 8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IEDFMFCO_01729 4e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IEDFMFCO_01731 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IEDFMFCO_01732 8.3e-110 ypsA S Belongs to the UPF0398 family
IEDFMFCO_01733 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IEDFMFCO_01734 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IEDFMFCO_01735 8.2e-179 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
IEDFMFCO_01736 6.4e-182 ftpB P Bacterial extracellular solute-binding protein
IEDFMFCO_01737 3.5e-302 ftpA P Binding-protein-dependent transport system inner membrane component
IEDFMFCO_01738 4.4e-83 uspA T Universal stress protein family
IEDFMFCO_01739 8e-157 metQ_4 P Belongs to the nlpA lipoprotein family
IEDFMFCO_01740 2e-99 metI P ABC transporter permease
IEDFMFCO_01741 4.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEDFMFCO_01743 1.3e-128 dnaD L Replication initiation and membrane attachment
IEDFMFCO_01744 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IEDFMFCO_01745 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IEDFMFCO_01746 2.1e-72 ypmB S protein conserved in bacteria
IEDFMFCO_01747 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IEDFMFCO_01748 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IEDFMFCO_01749 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IEDFMFCO_01750 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IEDFMFCO_01751 6.2e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IEDFMFCO_01752 2.1e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IEDFMFCO_01753 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IEDFMFCO_01754 2.5e-250 malT G Major Facilitator
IEDFMFCO_01755 1.9e-89 S Domain of unknown function (DUF4767)
IEDFMFCO_01756 5.5e-269 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IEDFMFCO_01757 1.2e-149 yitU 3.1.3.104 S hydrolase
IEDFMFCO_01758 2.6e-264 yfnA E Amino Acid
IEDFMFCO_01759 8.7e-259 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEDFMFCO_01760 1.3e-42
IEDFMFCO_01761 3.9e-50
IEDFMFCO_01762 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
IEDFMFCO_01763 1e-170 2.5.1.74 H UbiA prenyltransferase family
IEDFMFCO_01764 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IEDFMFCO_01765 5.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IEDFMFCO_01766 8.6e-281 pipD E Dipeptidase
IEDFMFCO_01767 9.4e-40
IEDFMFCO_01768 4.8e-29 S CsbD-like
IEDFMFCO_01769 6.5e-41 S transglycosylase associated protein
IEDFMFCO_01770 3.1e-14
IEDFMFCO_01771 1.3e-35
IEDFMFCO_01772 1.8e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
IEDFMFCO_01773 8e-66 S Protein of unknown function (DUF805)
IEDFMFCO_01774 1.4e-75 uspA T Belongs to the universal stress protein A family
IEDFMFCO_01775 4.3e-67 tspO T TspO/MBR family
IEDFMFCO_01776 7.9e-41
IEDFMFCO_01777 5.8e-48 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
IEDFMFCO_01778 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
IEDFMFCO_01779 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IEDFMFCO_01780 1.6e-28
IEDFMFCO_01781 1.1e-53
IEDFMFCO_01783 4e-09
IEDFMFCO_01786 1.2e-25 L Phage integrase, N-terminal SAM-like domain
IEDFMFCO_01787 1.9e-26 L Pfam:Integrase_AP2
IEDFMFCO_01788 4.4e-139 f42a O Band 7 protein
IEDFMFCO_01789 1.2e-302 norB EGP Major Facilitator
IEDFMFCO_01790 6.8e-93 K transcriptional regulator
IEDFMFCO_01791 1.7e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IEDFMFCO_01792 4.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
IEDFMFCO_01793 2.7e-160 K LysR substrate binding domain
IEDFMFCO_01794 1.3e-123 S Protein of unknown function (DUF554)
IEDFMFCO_01795 2.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IEDFMFCO_01796 1.3e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IEDFMFCO_01797 8.8e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IEDFMFCO_01798 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IEDFMFCO_01799 2.1e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IEDFMFCO_01800 1.2e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IEDFMFCO_01801 5.9e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IEDFMFCO_01802 3.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IEDFMFCO_01803 1.2e-126 IQ reductase
IEDFMFCO_01804 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IEDFMFCO_01805 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEDFMFCO_01806 7.7e-180 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEDFMFCO_01807 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IEDFMFCO_01808 3.8e-179 yneE K Transcriptional regulator
IEDFMFCO_01809 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFMFCO_01810 2.7e-58 S Protein of unknown function (DUF1648)
IEDFMFCO_01811 5.1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IEDFMFCO_01812 2.9e-215 3.5.1.47 E Peptidase family M20/M25/M40
IEDFMFCO_01813 4.4e-217 E glutamate:sodium symporter activity
IEDFMFCO_01814 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
IEDFMFCO_01815 2.6e-177 1.6.5.5 C Zinc-binding dehydrogenase
IEDFMFCO_01816 1.5e-97 entB 3.5.1.19 Q Isochorismatase family
IEDFMFCO_01817 8.7e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IEDFMFCO_01818 3.9e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IEDFMFCO_01819 2.2e-108 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IEDFMFCO_01820 2.4e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IEDFMFCO_01821 7.2e-165 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IEDFMFCO_01822 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
IEDFMFCO_01823 2.9e-268 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
IEDFMFCO_01825 8.1e-272 XK27_00765
IEDFMFCO_01826 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
IEDFMFCO_01827 1.4e-86
IEDFMFCO_01828 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
IEDFMFCO_01829 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
IEDFMFCO_01830 2e-180 D Alpha beta
IEDFMFCO_01831 5.9e-214 mdtG EGP Major facilitator Superfamily
IEDFMFCO_01832 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
IEDFMFCO_01833 9.4e-65 ycgX S Protein of unknown function (DUF1398)
IEDFMFCO_01834 1.1e-49
IEDFMFCO_01835 3.4e-25
IEDFMFCO_01836 7.4e-248 lmrB EGP Major facilitator Superfamily
IEDFMFCO_01837 3.5e-73 S COG NOG18757 non supervised orthologous group
IEDFMFCO_01838 7.4e-40
IEDFMFCO_01839 9.4e-74 copR K Copper transport repressor CopY TcrY
IEDFMFCO_01840 0.0 copB 3.6.3.4 P P-type ATPase
IEDFMFCO_01841 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IEDFMFCO_01842 6.8e-111 S VIT family
IEDFMFCO_01843 1.8e-119 S membrane
IEDFMFCO_01844 1.6e-158 EG EamA-like transporter family
IEDFMFCO_01845 1.3e-81 elaA S GNAT family
IEDFMFCO_01846 1.1e-115 GM NmrA-like family
IEDFMFCO_01847 2.1e-14
IEDFMFCO_01848 2e-55
IEDFMFCO_01849 3.4e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
IEDFMFCO_01850 3.1e-84
IEDFMFCO_01851 1.9e-62
IEDFMFCO_01852 4.1e-214 mutY L A G-specific adenine glycosylase
IEDFMFCO_01853 4e-53
IEDFMFCO_01854 1.7e-66 yeaO S Protein of unknown function, DUF488
IEDFMFCO_01855 2e-70 spx4 1.20.4.1 P ArsC family
IEDFMFCO_01856 1.6e-65 K Winged helix DNA-binding domain
IEDFMFCO_01857 4.8e-162 azoB GM NmrA-like family
IEDFMFCO_01858 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IEDFMFCO_01859 5.2e-167 S Alpha/beta hydrolase of unknown function (DUF915)
IEDFMFCO_01860 2.4e-251 cycA E Amino acid permease
IEDFMFCO_01861 1.2e-255 nhaC C Na H antiporter NhaC
IEDFMFCO_01862 6.1e-27 3.2.2.10 S Belongs to the LOG family
IEDFMFCO_01863 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IEDFMFCO_01864 9.8e-255 gor 1.8.1.7 C Glutathione reductase
IEDFMFCO_01865 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
IEDFMFCO_01866 6.7e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
IEDFMFCO_01867 2.8e-212 gntP EG Gluconate
IEDFMFCO_01868 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IEDFMFCO_01869 9.3e-188 yueF S AI-2E family transporter
IEDFMFCO_01870 1.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IEDFMFCO_01871 4.2e-145 pbpX V Beta-lactamase
IEDFMFCO_01872 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
IEDFMFCO_01873 7.8e-48 K sequence-specific DNA binding
IEDFMFCO_01874 1.5e-133 cwlO M NlpC/P60 family
IEDFMFCO_01875 4.1e-106 ygaC J Belongs to the UPF0374 family
IEDFMFCO_01876 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
IEDFMFCO_01877 1.1e-124
IEDFMFCO_01878 9.8e-100 K DNA-templated transcription, initiation
IEDFMFCO_01879 6.2e-25
IEDFMFCO_01880 7e-30
IEDFMFCO_01881 7.3e-33 S Protein of unknown function (DUF2922)
IEDFMFCO_01882 3.8e-53
IEDFMFCO_01883 3.2e-121 rfbP M Bacterial sugar transferase
IEDFMFCO_01884 1.1e-259 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
IEDFMFCO_01885 9.6e-74 K helix_turn_helix multiple antibiotic resistance protein
IEDFMFCO_01886 0.0 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IEDFMFCO_01887 4.7e-137 K helix_turn_helix, arabinose operon control protein
IEDFMFCO_01888 4e-147 cps1D M Domain of unknown function (DUF4422)
IEDFMFCO_01889 1.3e-170 cps3I G Acyltransferase family
IEDFMFCO_01890 1.3e-207 cps3H
IEDFMFCO_01891 2.7e-163 cps3F
IEDFMFCO_01892 4.8e-111 cps3E
IEDFMFCO_01893 6.5e-204 cps3D
IEDFMFCO_01894 4.2e-222 glf 5.4.99.9 M UDP-galactopyranose mutase
IEDFMFCO_01895 3.7e-176 cps3B S Glycosyltransferase like family 2
IEDFMFCO_01896 3.9e-170 cps3A S Glycosyltransferase like family 2
IEDFMFCO_01897 7.2e-28 S Barstar (barnase inhibitor)
IEDFMFCO_01898 5.5e-55 S Immunity protein 63
IEDFMFCO_01900 2.2e-120
IEDFMFCO_01901 1.5e-15
IEDFMFCO_01902 5e-151 L Transposase and inactivated derivatives, IS30 family
IEDFMFCO_01903 1e-10
IEDFMFCO_01904 4.4e-112
IEDFMFCO_01905 1.2e-134
IEDFMFCO_01906 1.1e-30
IEDFMFCO_01907 1.4e-35
IEDFMFCO_01908 2.1e-120
IEDFMFCO_01910 2.4e-43
IEDFMFCO_01911 1.5e-57 M self proteolysis
IEDFMFCO_01912 1.1e-22 M self proteolysis
IEDFMFCO_01913 1.9e-19 M domain protein
IEDFMFCO_01914 2.2e-102 M domain protein
IEDFMFCO_01915 1.3e-20 relB L bacterial-type proximal promoter sequence-specific DNA binding
IEDFMFCO_01916 3.2e-83 cps2J S Polysaccharide biosynthesis protein
IEDFMFCO_01917 9.9e-48 epsI GM Exopolysaccharide biosynthesis protein
IEDFMFCO_01918 5.8e-132 cps4I M Glycosyltransferase like family 2
IEDFMFCO_01919 9e-173
IEDFMFCO_01920 8.7e-126 cps4G M Glycosyltransferase Family 4
IEDFMFCO_01921 1.3e-132 cps4F 2.4.1.306 GT4 M Glycosyl transferases group 1
IEDFMFCO_01922 2.4e-124 tuaA M Bacterial sugar transferase
IEDFMFCO_01923 3.8e-176 cps2D 5.1.3.2 M RmlD substrate binding domain
IEDFMFCO_01924 2e-143 ywqE 3.1.3.48 GM PHP domain protein
IEDFMFCO_01925 7.3e-127 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IEDFMFCO_01926 7.4e-130 epsB M biosynthesis protein
IEDFMFCO_01927 3.3e-101 L Integrase
IEDFMFCO_01928 1.9e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IEDFMFCO_01929 6.7e-101 M Parallel beta-helix repeats
IEDFMFCO_01930 2.4e-63 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IEDFMFCO_01931 2.6e-173 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
IEDFMFCO_01932 7.9e-59 1.1.1.133 S Glycosyltransferase like family 2
IEDFMFCO_01933 5.6e-54 tagB 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IEDFMFCO_01934 1.2e-93 waaB GT4 M Glycosyl transferases group 1
IEDFMFCO_01935 3.5e-79 cps1D M Domain of unknown function (DUF4422)
IEDFMFCO_01936 1.4e-24
IEDFMFCO_01937 3e-10 pbpX2 V Beta-lactamase
IEDFMFCO_01938 1.5e-08 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IEDFMFCO_01939 3.4e-19 wcoI 2.7.10.1, 2.7.10.2 M biosynthesis protein
IEDFMFCO_01940 7.6e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
IEDFMFCO_01941 6.3e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IEDFMFCO_01942 3.3e-156 yihY S Belongs to the UPF0761 family
IEDFMFCO_01943 6.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IEDFMFCO_01944 5.3e-220 pbpX1 V Beta-lactamase
IEDFMFCO_01945 7.6e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IEDFMFCO_01946 5e-107
IEDFMFCO_01947 1.3e-73
IEDFMFCO_01949 6.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
IEDFMFCO_01950 1e-243 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_01951 2.3e-75 T Universal stress protein family
IEDFMFCO_01953 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
IEDFMFCO_01954 5.4e-189 mocA S Oxidoreductase
IEDFMFCO_01955 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
IEDFMFCO_01956 1.1e-62 S Domain of unknown function (DUF4828)
IEDFMFCO_01957 1.2e-143 lys M Glycosyl hydrolases family 25
IEDFMFCO_01958 1.9e-150 gntR K rpiR family
IEDFMFCO_01959 2.3e-167 S Alpha/beta hydrolase of unknown function (DUF915)
IEDFMFCO_01960 3.8e-235 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_01961 0.0 yfgQ P E1-E2 ATPase
IEDFMFCO_01962 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
IEDFMFCO_01963 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEDFMFCO_01964 1e-190 yegS 2.7.1.107 G Lipid kinase
IEDFMFCO_01965 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEDFMFCO_01966 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IEDFMFCO_01967 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEDFMFCO_01968 2.6e-198 camS S sex pheromone
IEDFMFCO_01969 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IEDFMFCO_01970 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IEDFMFCO_01971 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IEDFMFCO_01972 1e-93 S UPF0316 protein
IEDFMFCO_01973 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IEDFMFCO_01974 1.3e-111 acmA 3.2.1.17 NU mannosyl-glycoprotein
IEDFMFCO_01976 8.7e-184 S Oxidoreductase family, NAD-binding Rossmann fold
IEDFMFCO_01977 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IEDFMFCO_01978 2.3e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IEDFMFCO_01979 1.5e-156 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
IEDFMFCO_01980 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IEDFMFCO_01981 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IEDFMFCO_01982 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IEDFMFCO_01983 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
IEDFMFCO_01984 0.0 S Alpha beta
IEDFMFCO_01985 2.2e-24
IEDFMFCO_01986 3e-99 S ECF transporter, substrate-specific component
IEDFMFCO_01987 5.8e-253 yfnA E Amino Acid
IEDFMFCO_01988 1.4e-165 mleP S Sodium Bile acid symporter family
IEDFMFCO_01989 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IEDFMFCO_01990 1.8e-167 mleR K LysR family
IEDFMFCO_01991 4.5e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
IEDFMFCO_01992 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
IEDFMFCO_01993 1.1e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IEDFMFCO_01994 3.8e-152 ywkB S Membrane transport protein
IEDFMFCO_01995 6.7e-164 yvgN C Aldo keto reductase
IEDFMFCO_01996 9.2e-133 thrE S Putative threonine/serine exporter
IEDFMFCO_01997 2e-77 S Threonine/Serine exporter, ThrE
IEDFMFCO_01998 2.3e-43 S Protein of unknown function (DUF1093)
IEDFMFCO_01999 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IEDFMFCO_02000 2.7e-91 ymdB S Macro domain protein
IEDFMFCO_02001 4.4e-95 K transcriptional regulator
IEDFMFCO_02002 5.5e-50 yvlA
IEDFMFCO_02003 1e-160 ypuA S Protein of unknown function (DUF1002)
IEDFMFCO_02004 0.0
IEDFMFCO_02005 2.2e-185 S Bacterial protein of unknown function (DUF916)
IEDFMFCO_02006 1.7e-129 S WxL domain surface cell wall-binding
IEDFMFCO_02007 1.5e-135 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
IEDFMFCO_02008 1.2e-88 K Winged helix DNA-binding domain
IEDFMFCO_02009 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
IEDFMFCO_02010 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IEDFMFCO_02011 1.8e-27
IEDFMFCO_02012 4.8e-284 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
IEDFMFCO_02013 1.5e-75 mltD CBM50 M PFAM NLP P60 protein
IEDFMFCO_02014 2.5e-53
IEDFMFCO_02015 4.2e-62
IEDFMFCO_02017 8.6e-13
IEDFMFCO_02018 2.8e-65 XK27_09885 V VanZ like family
IEDFMFCO_02020 1.3e-11 K Cro/C1-type HTH DNA-binding domain
IEDFMFCO_02021 9.5e-109
IEDFMFCO_02022 1.3e-53 S Uncharacterized protein conserved in bacteria (DUF2316)
IEDFMFCO_02023 1.4e-160 4.1.1.46 S Amidohydrolase
IEDFMFCO_02024 9e-104 K transcriptional regulator
IEDFMFCO_02025 4.2e-183 yfeX P Peroxidase
IEDFMFCO_02026 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IEDFMFCO_02027 2.6e-129 ydcF S Gram-negative-bacterium-type cell wall biogenesis
IEDFMFCO_02028 2.3e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IEDFMFCO_02030 3e-252 dtpT U amino acid peptide transporter
IEDFMFCO_02031 2e-151 yjjH S Calcineurin-like phosphoesterase
IEDFMFCO_02035 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
IEDFMFCO_02036 3.2e-53 S Cupin domain
IEDFMFCO_02037 1.1e-166 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IEDFMFCO_02038 7.5e-192 ybiR P Citrate transporter
IEDFMFCO_02039 2.4e-150 pnuC H nicotinamide mononucleotide transporter
IEDFMFCO_02040 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEDFMFCO_02041 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IEDFMFCO_02042 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
IEDFMFCO_02043 1.3e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IEDFMFCO_02044 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IEDFMFCO_02045 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IEDFMFCO_02046 0.0 pacL 3.6.3.8 P P-type ATPase
IEDFMFCO_02047 8.9e-72
IEDFMFCO_02048 0.0 yhgF K Tex-like protein N-terminal domain protein
IEDFMFCO_02049 6.3e-81 ydcK S Belongs to the SprT family
IEDFMFCO_02050 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IEDFMFCO_02051 1.4e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IEDFMFCO_02053 4.9e-09 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
IEDFMFCO_02054 4.2e-20
IEDFMFCO_02055 0.0 ybfG M peptidoglycan-binding domain-containing protein
IEDFMFCO_02058 2.4e-160 G Peptidase_C39 like family
IEDFMFCO_02059 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IEDFMFCO_02060 3.4e-133 manY G PTS system
IEDFMFCO_02061 3.6e-171 manN G system, mannose fructose sorbose family IID component
IEDFMFCO_02062 4.7e-64 S Domain of unknown function (DUF956)
IEDFMFCO_02063 0.0 levR K Sigma-54 interaction domain
IEDFMFCO_02064 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
IEDFMFCO_02065 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
IEDFMFCO_02066 4.6e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEDFMFCO_02067 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
IEDFMFCO_02068 7.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
IEDFMFCO_02069 9.8e-141 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IEDFMFCO_02070 5.3e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
IEDFMFCO_02071 4.9e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IEDFMFCO_02072 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IEDFMFCO_02073 1.7e-177 EG EamA-like transporter family
IEDFMFCO_02074 2.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEDFMFCO_02075 1.1e-112 zmp2 O Zinc-dependent metalloprotease
IEDFMFCO_02076 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
IEDFMFCO_02077 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IEDFMFCO_02078 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
IEDFMFCO_02079 2.1e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IEDFMFCO_02080 6.7e-23
IEDFMFCO_02081 2.4e-22 plnF
IEDFMFCO_02082 2.2e-129 S CAAX protease self-immunity
IEDFMFCO_02083 3.7e-134 plnD K LytTr DNA-binding domain
IEDFMFCO_02084 1.1e-118 plnC K LytTr DNA-binding domain
IEDFMFCO_02085 1e-235 plnB 2.7.13.3 T GHKL domain
IEDFMFCO_02086 4.3e-18 plnA
IEDFMFCO_02087 8.4e-27
IEDFMFCO_02088 1.6e-116 plnP S CAAX protease self-immunity
IEDFMFCO_02089 9.8e-222 M Glycosyl transferase family 2
IEDFMFCO_02091 2.8e-28
IEDFMFCO_02092 3.5e-24 plnJ
IEDFMFCO_02093 5.2e-23 plnK
IEDFMFCO_02094 1.7e-117
IEDFMFCO_02095 2.9e-17 plnR
IEDFMFCO_02096 7.2e-32
IEDFMFCO_02098 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IEDFMFCO_02099 3.2e-256 brnQ U Component of the transport system for branched-chain amino acids
IEDFMFCO_02100 1.4e-150 S hydrolase
IEDFMFCO_02101 3.3e-166 K Transcriptional regulator
IEDFMFCO_02102 2e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
IEDFMFCO_02103 2e-195 uhpT EGP Major facilitator Superfamily
IEDFMFCO_02104 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IEDFMFCO_02105 2.4e-38
IEDFMFCO_02106 5.6e-68 S Immunity protein 63
IEDFMFCO_02107 1.2e-64
IEDFMFCO_02108 1.7e-39
IEDFMFCO_02109 6.5e-33
IEDFMFCO_02110 1.4e-175
IEDFMFCO_02111 2.3e-240 xylP1 G MFS/sugar transport protein
IEDFMFCO_02112 3e-122 qmcA O prohibitin homologues
IEDFMFCO_02113 1.5e-29
IEDFMFCO_02114 5e-281 pipD E Dipeptidase
IEDFMFCO_02115 3e-40
IEDFMFCO_02116 6.8e-96 bioY S BioY family
IEDFMFCO_02117 2.7e-177 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IEDFMFCO_02118 1.9e-60 S CHY zinc finger
IEDFMFCO_02119 6.3e-224 mtnE 2.6.1.83 E Aminotransferase
IEDFMFCO_02120 2.2e-218
IEDFMFCO_02121 3.5e-154 tagG U Transport permease protein
IEDFMFCO_02122 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IEDFMFCO_02123 3.8e-44
IEDFMFCO_02124 3.9e-93 K Transcriptional regulator PadR-like family
IEDFMFCO_02125 2.1e-258 P Major Facilitator Superfamily
IEDFMFCO_02126 2.5e-242 amtB P ammonium transporter
IEDFMFCO_02127 7.5e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IEDFMFCO_02128 3.7e-44
IEDFMFCO_02129 6.3e-102 zmp1 O Zinc-dependent metalloprotease
IEDFMFCO_02130 2.3e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IEDFMFCO_02131 3.1e-310 mco Q Multicopper oxidase
IEDFMFCO_02132 3.2e-54 ypaA S Protein of unknown function (DUF1304)
IEDFMFCO_02133 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
IEDFMFCO_02134 1.1e-231 flhF N Uncharacterized conserved protein (DUF2075)
IEDFMFCO_02135 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
IEDFMFCO_02136 9.3e-80
IEDFMFCO_02137 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IEDFMFCO_02138 7.7e-174 rihC 3.2.2.1 F Nucleoside
IEDFMFCO_02139 3e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFMFCO_02140 3e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IEDFMFCO_02141 9.9e-180 proV E ABC transporter, ATP-binding protein
IEDFMFCO_02142 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
IEDFMFCO_02143 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IEDFMFCO_02144 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
IEDFMFCO_02145 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IEDFMFCO_02146 0.0 M domain protein
IEDFMFCO_02147 4.9e-23 M dTDP-4-dehydrorhamnose reductase activity
IEDFMFCO_02148 2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IEDFMFCO_02149 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IEDFMFCO_02150 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IEDFMFCO_02151 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IEDFMFCO_02152 1.3e-116 radC L DNA repair protein
IEDFMFCO_02153 2.8e-161 mreB D cell shape determining protein MreB
IEDFMFCO_02154 2.6e-144 mreC M Involved in formation and maintenance of cell shape
IEDFMFCO_02155 1.2e-88 mreD M rod shape-determining protein MreD
IEDFMFCO_02156 1.4e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IEDFMFCO_02157 1.2e-146 minD D Belongs to the ParA family
IEDFMFCO_02158 4.6e-109 glnP P ABC transporter permease
IEDFMFCO_02159 2.8e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IEDFMFCO_02160 1.5e-155 aatB ET ABC transporter substrate-binding protein
IEDFMFCO_02161 1e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
IEDFMFCO_02162 6.5e-232 ymfF S Peptidase M16 inactive domain protein
IEDFMFCO_02163 2.9e-251 ymfH S Peptidase M16
IEDFMFCO_02164 5.7e-110 ymfM S Helix-turn-helix domain
IEDFMFCO_02165 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEDFMFCO_02166 9.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
IEDFMFCO_02167 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IEDFMFCO_02168 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
IEDFMFCO_02169 2.7e-154 ymdB S YmdB-like protein
IEDFMFCO_02170 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IEDFMFCO_02171 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IEDFMFCO_02172 1.8e-278
IEDFMFCO_02173 6.5e-198 M MucBP domain
IEDFMFCO_02174 7.1e-161 lysR5 K LysR substrate binding domain
IEDFMFCO_02175 5.5e-126 yxaA S membrane transporter protein
IEDFMFCO_02176 3.2e-57 ywjH S Protein of unknown function (DUF1634)
IEDFMFCO_02177 1.3e-309 oppA E ABC transporter, substratebinding protein
IEDFMFCO_02178 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEDFMFCO_02179 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEDFMFCO_02180 9.2e-203 oppD P Belongs to the ABC transporter superfamily
IEDFMFCO_02181 1.8e-181 oppF P Belongs to the ABC transporter superfamily
IEDFMFCO_02182 1e-63 K Winged helix DNA-binding domain
IEDFMFCO_02183 1.6e-102 L Integrase
IEDFMFCO_02184 0.0 clpE O Belongs to the ClpA ClpB family
IEDFMFCO_02185 6.5e-30
IEDFMFCO_02186 2.7e-39 ptsH G phosphocarrier protein HPR
IEDFMFCO_02187 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEDFMFCO_02188 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IEDFMFCO_02189 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
IEDFMFCO_02190 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IEDFMFCO_02191 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IEDFMFCO_02192 1.8e-228 patA 2.6.1.1 E Aminotransferase
IEDFMFCO_02193 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
IEDFMFCO_02194 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IEDFMFCO_02195 3.4e-258 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
IEDFMFCO_02196 1.2e-155 mleP3 S Membrane transport protein
IEDFMFCO_02197 7.5e-110 S Membrane
IEDFMFCO_02198 9.1e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IEDFMFCO_02199 1.1e-98 1.5.1.3 H RibD C-terminal domain
IEDFMFCO_02200 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IEDFMFCO_02201 1.4e-90 2.7.7.65 T phosphorelay sensor kinase activity
IEDFMFCO_02202 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IEDFMFCO_02203 2.9e-172 hrtB V ABC transporter permease
IEDFMFCO_02204 6.6e-95 S Protein of unknown function (DUF1440)
IEDFMFCO_02205 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEDFMFCO_02206 6.4e-148 KT helix_turn_helix, mercury resistance
IEDFMFCO_02207 1.6e-115 S Protein of unknown function (DUF554)
IEDFMFCO_02208 1.8e-92 ogt 2.1.1.63 L Methyltransferase
IEDFMFCO_02209 7e-54 lytE M LysM domain
IEDFMFCO_02211 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
IEDFMFCO_02212 1.2e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IEDFMFCO_02213 3.7e-151 rlrG K Transcriptional regulator
IEDFMFCO_02214 1.2e-172 S Conserved hypothetical protein 698
IEDFMFCO_02215 4e-99 rimL J Acetyltransferase (GNAT) domain
IEDFMFCO_02216 2e-75 S Domain of unknown function (DUF4811)
IEDFMFCO_02217 1.1e-270 lmrB EGP Major facilitator Superfamily
IEDFMFCO_02218 1.8e-124 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IEDFMFCO_02219 4.9e-189 ynfM EGP Major facilitator Superfamily
IEDFMFCO_02220 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
IEDFMFCO_02222 1.1e-92 K Bacterial regulatory proteins, tetR family
IEDFMFCO_02223 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IEDFMFCO_02224 5e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IEDFMFCO_02225 1.9e-101 dhaL 2.7.1.121 S Dak2
IEDFMFCO_02226 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
IEDFMFCO_02227 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IEDFMFCO_02228 1e-190 malR K Transcriptional regulator, LacI family
IEDFMFCO_02229 2e-180 yvdE K helix_turn _helix lactose operon repressor
IEDFMFCO_02230 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IEDFMFCO_02231 2.1e-230 mdxE G Bacterial extracellular solute-binding protein
IEDFMFCO_02232 4.9e-227 malC P Binding-protein-dependent transport system inner membrane component
IEDFMFCO_02233 1.4e-161 malD P ABC transporter permease
IEDFMFCO_02234 1.8e-150 malA S maltodextrose utilization protein MalA
IEDFMFCO_02235 4.5e-260 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
IEDFMFCO_02236 4e-209 msmK P Belongs to the ABC transporter superfamily
IEDFMFCO_02237 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IEDFMFCO_02238 0.0 3.2.1.96 G Glycosyl hydrolase family 85
IEDFMFCO_02239 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
IEDFMFCO_02240 1.8e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IEDFMFCO_02241 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
IEDFMFCO_02242 1.4e-305 scrB 3.2.1.26 GH32 G invertase
IEDFMFCO_02243 9.1e-173 scrR K Transcriptional regulator, LacI family
IEDFMFCO_02244 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IEDFMFCO_02245 1.3e-165 3.5.1.10 C nadph quinone reductase
IEDFMFCO_02246 1.1e-217 nhaC C Na H antiporter NhaC
IEDFMFCO_02247 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IEDFMFCO_02248 7.7e-166 mleR K LysR substrate binding domain
IEDFMFCO_02249 0.0 3.6.4.13 M domain protein
IEDFMFCO_02251 2.1e-157 hipB K Helix-turn-helix
IEDFMFCO_02252 0.0 oppA E ABC transporter, substratebinding protein
IEDFMFCO_02253 8.6e-309 oppA E ABC transporter, substratebinding protein
IEDFMFCO_02254 2.7e-49 yiaC K Acetyltransferase (GNAT) domain
IEDFMFCO_02255 8.8e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEDFMFCO_02256 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IEDFMFCO_02257 6.7e-113 pgm1 G phosphoglycerate mutase
IEDFMFCO_02258 2.9e-179 yghZ C Aldo keto reductase family protein
IEDFMFCO_02259 4.9e-34
IEDFMFCO_02260 4.8e-60 S Domain of unknown function (DU1801)
IEDFMFCO_02261 3.8e-162 FbpA K Domain of unknown function (DUF814)
IEDFMFCO_02262 1e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEDFMFCO_02264 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEDFMFCO_02265 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEDFMFCO_02266 9.5e-262 S ATPases associated with a variety of cellular activities
IEDFMFCO_02267 5.2e-116 P cobalt transport
IEDFMFCO_02268 1.4e-259 P ABC transporter
IEDFMFCO_02269 3.1e-101 S ABC transporter permease
IEDFMFCO_02270 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IEDFMFCO_02271 1.4e-158 dkgB S reductase
IEDFMFCO_02272 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEDFMFCO_02273 1e-69
IEDFMFCO_02274 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IEDFMFCO_02276 3.9e-278 pipD E Dipeptidase
IEDFMFCO_02277 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
IEDFMFCO_02278 0.0 mtlR K Mga helix-turn-helix domain
IEDFMFCO_02279 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_02280 4.3e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
IEDFMFCO_02281 2.1e-73
IEDFMFCO_02282 1.4e-56 trxA1 O Belongs to the thioredoxin family
IEDFMFCO_02283 1.1e-50
IEDFMFCO_02284 6.6e-96
IEDFMFCO_02285 2e-62
IEDFMFCO_02286 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
IEDFMFCO_02287 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
IEDFMFCO_02288 5.4e-98 yieF S NADPH-dependent FMN reductase
IEDFMFCO_02289 3.6e-123 K helix_turn_helix gluconate operon transcriptional repressor
IEDFMFCO_02290 5.1e-229 pts3C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_02291 4.7e-39
IEDFMFCO_02292 8.5e-212 S Bacterial protein of unknown function (DUF871)
IEDFMFCO_02293 2.3e-212 dho 3.5.2.3 S Amidohydrolase family
IEDFMFCO_02294 2.3e-201 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
IEDFMFCO_02295 4.6e-129 4.1.2.14 S KDGP aldolase
IEDFMFCO_02296 2.2e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
IEDFMFCO_02297 5.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IEDFMFCO_02298 9.8e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IEDFMFCO_02299 4.5e-166 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IEDFMFCO_02300 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
IEDFMFCO_02301 4.3e-141 pnuC H nicotinamide mononucleotide transporter
IEDFMFCO_02302 7.3e-43 S Protein of unknown function (DUF2089)
IEDFMFCO_02303 1.7e-42
IEDFMFCO_02304 3.5e-129 treR K UTRA
IEDFMFCO_02305 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IEDFMFCO_02306 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
IEDFMFCO_02307 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
IEDFMFCO_02308 1.4e-144
IEDFMFCO_02309 6.3e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IEDFMFCO_02310 4.6e-70
IEDFMFCO_02311 1.8e-72 K Transcriptional regulator
IEDFMFCO_02312 4.3e-121 K Bacterial regulatory proteins, tetR family
IEDFMFCO_02313 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
IEDFMFCO_02314 1.5e-115
IEDFMFCO_02315 1.7e-40
IEDFMFCO_02316 1e-40
IEDFMFCO_02317 9.7e-253 ydiC1 EGP Major facilitator Superfamily
IEDFMFCO_02318 3.3e-65 K helix_turn_helix, mercury resistance
IEDFMFCO_02319 2.2e-249 T PhoQ Sensor
IEDFMFCO_02320 4.4e-129 K Transcriptional regulatory protein, C terminal
IEDFMFCO_02321 9.2e-49
IEDFMFCO_02322 2.7e-129 yidA K Helix-turn-helix domain, rpiR family
IEDFMFCO_02323 3e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_02324 9.9e-57
IEDFMFCO_02325 2.1e-41
IEDFMFCO_02326 1.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IEDFMFCO_02327 1.1e-256 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
IEDFMFCO_02328 1.3e-47
IEDFMFCO_02329 2.7e-123 2.7.6.5 S RelA SpoT domain protein
IEDFMFCO_02330 3.1e-104 K transcriptional regulator
IEDFMFCO_02331 0.0 ydgH S MMPL family
IEDFMFCO_02332 1e-107 tag 3.2.2.20 L glycosylase
IEDFMFCO_02333 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IEDFMFCO_02334 1e-188 yclI V MacB-like periplasmic core domain
IEDFMFCO_02335 7.1e-121 yclH V ABC transporter
IEDFMFCO_02336 2.5e-114 V CAAX protease self-immunity
IEDFMFCO_02337 4.5e-121 S CAAX protease self-immunity
IEDFMFCO_02338 8.5e-52 M Lysin motif
IEDFMFCO_02339 1.2e-29 lytE M LysM domain protein
IEDFMFCO_02340 9.7e-67 gcvH E Glycine cleavage H-protein
IEDFMFCO_02341 7.4e-177 sepS16B
IEDFMFCO_02342 1.3e-131
IEDFMFCO_02343 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
IEDFMFCO_02344 6.8e-57
IEDFMFCO_02345 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEDFMFCO_02346 1.4e-77 elaA S GNAT family
IEDFMFCO_02347 1.7e-75 K Transcriptional regulator
IEDFMFCO_02348 7.8e-227 ndh 1.6.99.3 C NADH dehydrogenase
IEDFMFCO_02349 2.6e-37
IEDFMFCO_02350 2.5e-08 S Motility quorum-sensing regulator, toxin of MqsA
IEDFMFCO_02351 2.2e-30
IEDFMFCO_02352 7.1e-21 U Preprotein translocase subunit SecB
IEDFMFCO_02353 4e-206 potD P ABC transporter
IEDFMFCO_02354 3.4e-141 potC P ABC transporter permease
IEDFMFCO_02355 2.7e-149 potB P ABC transporter permease
IEDFMFCO_02356 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IEDFMFCO_02357 3.8e-96 puuR K Cupin domain
IEDFMFCO_02358 1.1e-83 6.3.3.2 S ASCH
IEDFMFCO_02359 1e-84 K GNAT family
IEDFMFCO_02360 2.6e-89 K acetyltransferase
IEDFMFCO_02361 8.1e-22
IEDFMFCO_02362 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
IEDFMFCO_02363 2e-163 ytrB V ABC transporter
IEDFMFCO_02364 3.2e-189
IEDFMFCO_02365 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
IEDFMFCO_02366 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IEDFMFCO_02367 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IEDFMFCO_02368 1.1e-138 yhfI S Metallo-beta-lactamase superfamily
IEDFMFCO_02369 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IEDFMFCO_02370 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IEDFMFCO_02371 8.1e-207 coiA 3.6.4.12 S Competence protein
IEDFMFCO_02372 0.0 pepF E oligoendopeptidase F
IEDFMFCO_02373 3.6e-114 yjbH Q Thioredoxin
IEDFMFCO_02374 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
IEDFMFCO_02375 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEDFMFCO_02376 8.9e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IEDFMFCO_02377 5.1e-116 cutC P Participates in the control of copper homeostasis
IEDFMFCO_02378 7.4e-194 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IEDFMFCO_02379 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IEDFMFCO_02380 8.1e-205 XK27_05220 S AI-2E family transporter
IEDFMFCO_02381 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEDFMFCO_02382 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
IEDFMFCO_02383 9.8e-210 brnQ U Component of the transport system for branched-chain amino acids
IEDFMFCO_02384 7e-113 ywnB S NAD(P)H-binding
IEDFMFCO_02385 4.5e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IEDFMFCO_02386 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IEDFMFCO_02387 1.9e-65 D nuclear chromosome segregation
IEDFMFCO_02388 2.9e-48 K Cro/C1-type HTH DNA-binding domain
IEDFMFCO_02389 1.3e-162 S Cysteine-rich secretory protein family
IEDFMFCO_02390 5.5e-234 EGP Major facilitator Superfamily
IEDFMFCO_02391 1.4e-56 hxlR K HxlR-like helix-turn-helix
IEDFMFCO_02392 1.1e-116 XK27_07075 V CAAX protease self-immunity
IEDFMFCO_02393 0.0 L AAA domain
IEDFMFCO_02394 1.7e-63 K Helix-turn-helix XRE-family like proteins
IEDFMFCO_02395 6.2e-50
IEDFMFCO_02396 2.1e-100 K Transcriptional regulator, AbiEi antitoxin
IEDFMFCO_02397 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
IEDFMFCO_02398 0.0 cadA P P-type ATPase
IEDFMFCO_02400 1.3e-122 yyaQ S YjbR
IEDFMFCO_02401 4.8e-221 S Uncharacterized protein conserved in bacteria (DUF2325)
IEDFMFCO_02402 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IEDFMFCO_02403 1.3e-199 frlB M SIS domain
IEDFMFCO_02404 6.2e-96 V VanZ like family
IEDFMFCO_02405 5e-195 blaA6 V Beta-lactamase
IEDFMFCO_02406 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
IEDFMFCO_02407 2.5e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IEDFMFCO_02408 5.1e-53 yitW S Pfam:DUF59
IEDFMFCO_02409 7.7e-174 S Aldo keto reductase
IEDFMFCO_02410 2.9e-30 FG HIT domain
IEDFMFCO_02411 1.5e-55 FG HIT domain
IEDFMFCO_02412 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
IEDFMFCO_02413 1.4e-77
IEDFMFCO_02414 1.4e-121 E GDSL-like Lipase/Acylhydrolase family
IEDFMFCO_02415 4.8e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IEDFMFCO_02416 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
IEDFMFCO_02417 1.5e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
IEDFMFCO_02418 5e-162 degV S Uncharacterised protein, DegV family COG1307
IEDFMFCO_02419 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEDFMFCO_02420 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
IEDFMFCO_02421 2.7e-39
IEDFMFCO_02422 0.0 pepO 3.4.24.71 O Peptidase family M13
IEDFMFCO_02423 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IEDFMFCO_02424 1.6e-32 copZ P Heavy-metal-associated domain
IEDFMFCO_02425 1.2e-94 dps P Belongs to the Dps family
IEDFMFCO_02426 1.6e-18
IEDFMFCO_02427 2.1e-39 yrkD S Metal-sensitive transcriptional repressor
IEDFMFCO_02428 9.5e-55 txlA O Thioredoxin-like domain
IEDFMFCO_02429 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IEDFMFCO_02430 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
IEDFMFCO_02431 1.1e-92 yueI S Protein of unknown function (DUF1694)
IEDFMFCO_02432 5.9e-143 yvpB S Peptidase_C39 like family
IEDFMFCO_02433 1.8e-160 M Glycosyl hydrolases family 25
IEDFMFCO_02434 1e-111
IEDFMFCO_02435 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IEDFMFCO_02436 1.8e-84 hmpT S Pfam:DUF3816
IEDFMFCO_02437 3.1e-19 K helix_turn_helix multiple antibiotic resistance protein
IEDFMFCO_02438 4e-150
IEDFMFCO_02439 1.5e-34 S Cell surface protein
IEDFMFCO_02442 2.1e-08 L Helix-turn-helix domain
IEDFMFCO_02443 1.8e-12 L Helix-turn-helix domain
IEDFMFCO_02445 1.7e-138 S MobA/MobL family
IEDFMFCO_02447 6.2e-143 sinIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
IEDFMFCO_02448 1.1e-35 L SinI restriction endonuclease
IEDFMFCO_02449 1.1e-28
IEDFMFCO_02450 6.9e-08
IEDFMFCO_02452 1.9e-16
IEDFMFCO_02454 4e-28
IEDFMFCO_02455 1.4e-50 K Helix-turn-helix XRE-family like proteins
IEDFMFCO_02456 7.1e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
IEDFMFCO_02457 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IEDFMFCO_02458 3e-99 L Integrase
IEDFMFCO_02459 3.1e-62
IEDFMFCO_02460 1.3e-31
IEDFMFCO_02461 5.7e-307 uup S ABC transporter, ATP-binding protein
IEDFMFCO_02462 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IEDFMFCO_02463 4.6e-109 ydiL S CAAX protease self-immunity
IEDFMFCO_02464 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IEDFMFCO_02465 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IEDFMFCO_02466 0.0 ydaO E amino acid
IEDFMFCO_02467 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
IEDFMFCO_02468 4.3e-145 pstS P Phosphate
IEDFMFCO_02469 5.7e-115 yvyE 3.4.13.9 S YigZ family
IEDFMFCO_02470 1.5e-258 comFA L Helicase C-terminal domain protein
IEDFMFCO_02471 7.5e-126 comFC S Competence protein
IEDFMFCO_02472 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IEDFMFCO_02473 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IEDFMFCO_02474 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IEDFMFCO_02475 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
IEDFMFCO_02476 1.5e-132 K response regulator
IEDFMFCO_02477 9.2e-251 phoR 2.7.13.3 T Histidine kinase
IEDFMFCO_02478 3e-151 pstS P Phosphate
IEDFMFCO_02479 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
IEDFMFCO_02480 1.5e-155 pstA P Phosphate transport system permease protein PstA
IEDFMFCO_02481 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEDFMFCO_02482 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEDFMFCO_02483 2.4e-116 phoU P Plays a role in the regulation of phosphate uptake
IEDFMFCO_02484 5.8e-49 pspC KT positive regulation of macromolecule biosynthetic process
IEDFMFCO_02485 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IEDFMFCO_02486 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IEDFMFCO_02487 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IEDFMFCO_02488 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IEDFMFCO_02489 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IEDFMFCO_02490 1.9e-124 yliE T Putative diguanylate phosphodiesterase
IEDFMFCO_02491 6.7e-270 nox C NADH oxidase
IEDFMFCO_02492 4.3e-163 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
IEDFMFCO_02493 4.6e-78
IEDFMFCO_02494 4.9e-155
IEDFMFCO_02495 3.8e-205 S Protein conserved in bacteria
IEDFMFCO_02496 6.8e-218 ydaM M Glycosyl transferase family group 2
IEDFMFCO_02497 0.0 ydaN S Bacterial cellulose synthase subunit
IEDFMFCO_02498 1e-132 2.7.7.65 T diguanylate cyclase activity
IEDFMFCO_02499 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IEDFMFCO_02500 2e-109 yviA S Protein of unknown function (DUF421)
IEDFMFCO_02501 1.1e-61 S Protein of unknown function (DUF3290)
IEDFMFCO_02502 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IEDFMFCO_02503 3.3e-132 yliE T Putative diguanylate phosphodiesterase
IEDFMFCO_02504 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IEDFMFCO_02505 1.1e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IEDFMFCO_02506 1.3e-210 norA EGP Major facilitator Superfamily
IEDFMFCO_02507 1.2e-117 yfbR S HD containing hydrolase-like enzyme
IEDFMFCO_02508 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IEDFMFCO_02509 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IEDFMFCO_02510 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IEDFMFCO_02511 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IEDFMFCO_02512 1.1e-264 argH 4.3.2.1 E argininosuccinate lyase
IEDFMFCO_02513 9.3e-87 S Short repeat of unknown function (DUF308)
IEDFMFCO_02514 1.1e-161 rapZ S Displays ATPase and GTPase activities
IEDFMFCO_02515 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IEDFMFCO_02516 3.7e-168 whiA K May be required for sporulation
IEDFMFCO_02517 4e-306 oppA E ABC transporter, substratebinding protein
IEDFMFCO_02518 1e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEDFMFCO_02519 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IEDFMFCO_02521 4.2e-245 rpoN K Sigma-54 factor, core binding domain
IEDFMFCO_02522 7.3e-189 cggR K Putative sugar-binding domain
IEDFMFCO_02523 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEDFMFCO_02524 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IEDFMFCO_02525 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IEDFMFCO_02526 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEDFMFCO_02527 4.1e-132
IEDFMFCO_02528 1.5e-294 clcA P chloride
IEDFMFCO_02529 1.2e-30 secG U Preprotein translocase
IEDFMFCO_02530 1.3e-139 est 3.1.1.1 S Serine aminopeptidase, S33
IEDFMFCO_02531 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IEDFMFCO_02532 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IEDFMFCO_02533 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
IEDFMFCO_02534 1.5e-256 glnP P ABC transporter
IEDFMFCO_02535 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IEDFMFCO_02536 4.6e-105 yxjI
IEDFMFCO_02537 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
IEDFMFCO_02538 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IEDFMFCO_02539 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IEDFMFCO_02540 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IEDFMFCO_02541 1.8e-87 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
IEDFMFCO_02542 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
IEDFMFCO_02543 1.4e-152 xth 3.1.11.2 L exodeoxyribonuclease III
IEDFMFCO_02544 1.9e-156 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IEDFMFCO_02545 6.2e-168 murB 1.3.1.98 M Cell wall formation
IEDFMFCO_02546 0.0 yjcE P Sodium proton antiporter
IEDFMFCO_02547 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
IEDFMFCO_02548 2.5e-121 S Protein of unknown function (DUF1361)
IEDFMFCO_02549 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEDFMFCO_02550 1.6e-129 ybbR S YbbR-like protein
IEDFMFCO_02551 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEDFMFCO_02552 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IEDFMFCO_02553 4.5e-123 yliE T EAL domain
IEDFMFCO_02554 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
IEDFMFCO_02555 3.1e-104 K Bacterial regulatory proteins, tetR family
IEDFMFCO_02556 1.6e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IEDFMFCO_02557 4e-19 3.4.21.88 K Transcriptional
IEDFMFCO_02559 2.4e-08 E Zn peptidase
IEDFMFCO_02560 8.1e-24 S Short C-terminal domain
IEDFMFCO_02562 4.3e-79 S KilA-N domain
IEDFMFCO_02564 3.8e-93 L Belongs to the 'phage' integrase family
IEDFMFCO_02565 4e-154 G Transmembrane secretion effector
IEDFMFCO_02566 3e-131 1.5.1.39 C nitroreductase
IEDFMFCO_02567 3e-72
IEDFMFCO_02568 3.3e-52
IEDFMFCO_02569 1.5e-42 S COG NOG38524 non supervised orthologous group
IEDFMFCO_02570 1.5e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEDFMFCO_02571 5.5e-08
IEDFMFCO_02574 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IEDFMFCO_02575 3.4e-35 yozE S Belongs to the UPF0346 family
IEDFMFCO_02576 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IEDFMFCO_02577 5.1e-149 ypmR E GDSL-like Lipase/Acylhydrolase
IEDFMFCO_02578 1.5e-147 DegV S EDD domain protein, DegV family
IEDFMFCO_02579 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEDFMFCO_02580 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IEDFMFCO_02581 0.0 yfmR S ABC transporter, ATP-binding protein
IEDFMFCO_02582 9.6e-85
IEDFMFCO_02583 1.1e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IEDFMFCO_02584 1.6e-143 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IEDFMFCO_02585 9.7e-149 3.1.3.102, 3.1.3.104 S hydrolase
IEDFMFCO_02586 4.7e-206 S Tetratricopeptide repeat protein
IEDFMFCO_02587 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IEDFMFCO_02588 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IEDFMFCO_02589 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
IEDFMFCO_02590 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IEDFMFCO_02591 2e-19 M Lysin motif
IEDFMFCO_02592 6.2e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IEDFMFCO_02593 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
IEDFMFCO_02594 3.2e-90 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IEDFMFCO_02595 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IEDFMFCO_02596 1.8e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IEDFMFCO_02597 8.2e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IEDFMFCO_02598 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEDFMFCO_02599 1.1e-164 xerD D recombinase XerD
IEDFMFCO_02600 2.9e-170 cvfB S S1 domain
IEDFMFCO_02601 1.5e-74 yeaL S Protein of unknown function (DUF441)
IEDFMFCO_02602 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IEDFMFCO_02603 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IEDFMFCO_02604 0.0 dnaE 2.7.7.7 L DNA polymerase
IEDFMFCO_02605 7.3e-29 S Protein of unknown function (DUF2929)
IEDFMFCO_02606 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IEDFMFCO_02607 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IEDFMFCO_02608 1.1e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEDFMFCO_02609 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
IEDFMFCO_02610 6.9e-223 M O-Antigen ligase
IEDFMFCO_02611 5.4e-120 drrB U ABC-2 type transporter
IEDFMFCO_02612 3.2e-167 drrA V ABC transporter
IEDFMFCO_02613 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
IEDFMFCO_02614 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IEDFMFCO_02615 7.8e-61 P Rhodanese Homology Domain
IEDFMFCO_02616 2.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
IEDFMFCO_02617 1.7e-207
IEDFMFCO_02618 1.2e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
IEDFMFCO_02619 1.1e-181 C Zinc-binding dehydrogenase
IEDFMFCO_02620 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
IEDFMFCO_02621 6.8e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEDFMFCO_02622 6.5e-241 EGP Major facilitator Superfamily
IEDFMFCO_02623 4.3e-77 K Transcriptional regulator
IEDFMFCO_02624 1.4e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IEDFMFCO_02625 2.8e-310 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IEDFMFCO_02626 8e-137 K DeoR C terminal sensor domain
IEDFMFCO_02627 3.1e-107 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
IEDFMFCO_02628 9.1e-71 yneH 1.20.4.1 P ArsC family
IEDFMFCO_02629 1.4e-68 S Protein of unknown function (DUF1722)
IEDFMFCO_02630 2.3e-113 GM epimerase
IEDFMFCO_02631 0.0 CP_1020 S Zinc finger, swim domain protein
IEDFMFCO_02632 1.4e-119 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
IEDFMFCO_02633 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IEDFMFCO_02634 3.8e-128 K Helix-turn-helix domain, rpiR family
IEDFMFCO_02635 3.4e-160 S Alpha beta hydrolase
IEDFMFCO_02636 9e-113 GM NmrA-like family
IEDFMFCO_02637 2.7e-76 S Uncharacterized protein conserved in bacteria (DUF2255)
IEDFMFCO_02638 8e-160 K Transcriptional regulator
IEDFMFCO_02639 1.8e-170 C nadph quinone reductase
IEDFMFCO_02640 4.7e-17 S Alpha beta hydrolase
IEDFMFCO_02641 1e-262 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IEDFMFCO_02642 3.6e-103 desR K helix_turn_helix, Lux Regulon
IEDFMFCO_02643 4.2e-203 desK 2.7.13.3 T Histidine kinase
IEDFMFCO_02644 1.3e-134 yvfS V ABC-2 type transporter
IEDFMFCO_02645 2.6e-158 yvfR V ABC transporter
IEDFMFCO_02647 6e-82 K Acetyltransferase (GNAT) domain
IEDFMFCO_02648 2.1e-73 K MarR family
IEDFMFCO_02649 3.8e-114 S Psort location CytoplasmicMembrane, score
IEDFMFCO_02650 2.6e-135 V ABC transporter, ATP-binding protein
IEDFMFCO_02651 2.3e-128 S ABC-2 family transporter protein
IEDFMFCO_02652 3.6e-199
IEDFMFCO_02653 9.2e-203
IEDFMFCO_02654 4.8e-165 ytrB V ABC transporter, ATP-binding protein
IEDFMFCO_02655 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
IEDFMFCO_02656 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IEDFMFCO_02657 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IEDFMFCO_02658 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IEDFMFCO_02659 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IEDFMFCO_02660 3.4e-146 recO L Involved in DNA repair and RecF pathway recombination
IEDFMFCO_02661 5.6e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEDFMFCO_02662 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IEDFMFCO_02663 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IEDFMFCO_02664 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
IEDFMFCO_02665 2.6e-71 yqeY S YqeY-like protein
IEDFMFCO_02666 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IEDFMFCO_02667 3.6e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IEDFMFCO_02668 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
IEDFMFCO_02669 4.5e-171 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IEDFMFCO_02670 2e-224 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IEDFMFCO_02671 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEDFMFCO_02672 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IEDFMFCO_02673 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IEDFMFCO_02674 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
IEDFMFCO_02675 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IEDFMFCO_02676 1.2e-165 yniA G Fructosamine kinase
IEDFMFCO_02677 2.2e-116 3.1.3.18 J HAD-hyrolase-like
IEDFMFCO_02678 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IEDFMFCO_02679 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEDFMFCO_02680 9.6e-58
IEDFMFCO_02681 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IEDFMFCO_02682 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
IEDFMFCO_02683 3.6e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IEDFMFCO_02684 1.4e-49
IEDFMFCO_02685 1.4e-49
IEDFMFCO_02686 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEDFMFCO_02687 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IEDFMFCO_02688 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFMFCO_02689 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
IEDFMFCO_02690 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFMFCO_02691 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
IEDFMFCO_02692 2.8e-197 pbpX2 V Beta-lactamase
IEDFMFCO_02693 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IEDFMFCO_02694 0.0 dnaK O Heat shock 70 kDa protein
IEDFMFCO_02695 5.6e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IEDFMFCO_02696 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IEDFMFCO_02697 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
IEDFMFCO_02698 1.2e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IEDFMFCO_02699 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IEDFMFCO_02700 2.4e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IEDFMFCO_02701 1.3e-196 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IEDFMFCO_02702 4.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IEDFMFCO_02703 8.5e-93
IEDFMFCO_02704 4.6e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IEDFMFCO_02705 9.7e-264 ydiN 5.4.99.5 G Major Facilitator
IEDFMFCO_02706 8.7e-235 mepA V MATE efflux family protein
IEDFMFCO_02707 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
IEDFMFCO_02708 5.2e-184 1.1.1.1 C nadph quinone reductase
IEDFMFCO_02709 2e-126 hchA S DJ-1/PfpI family
IEDFMFCO_02710 3.6e-93 MA20_25245 K FR47-like protein
IEDFMFCO_02711 2.8e-152 EG EamA-like transporter family
IEDFMFCO_02712 1.4e-62 S Protein of unknown function
IEDFMFCO_02713 1.2e-45 S Protein of unknown function
IEDFMFCO_02714 0.0 tetP J elongation factor G
IEDFMFCO_02715 3.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEDFMFCO_02716 2e-169 yobV1 K WYL domain
IEDFMFCO_02717 4.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
IEDFMFCO_02718 2.9e-81 6.3.3.2 S ASCH
IEDFMFCO_02719 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
IEDFMFCO_02720 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
IEDFMFCO_02721 1e-244 yjjP S Putative threonine/serine exporter
IEDFMFCO_02722 6e-196 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IEDFMFCO_02723 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IEDFMFCO_02724 6.4e-290 QT PucR C-terminal helix-turn-helix domain
IEDFMFCO_02725 1.3e-122 drgA C Nitroreductase family
IEDFMFCO_02726 7.1e-158 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IEDFMFCO_02727 2e-163 ptlF S KR domain
IEDFMFCO_02728 3.2e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEDFMFCO_02729 1.1e-71 C FMN binding
IEDFMFCO_02730 7.3e-65 K LysR family
IEDFMFCO_02731 2.4e-78 K LysR family
IEDFMFCO_02732 2.9e-257 P Sodium:sulfate symporter transmembrane region
IEDFMFCO_02733 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
IEDFMFCO_02734 5.7e-115 S Elongation factor G-binding protein, N-terminal
IEDFMFCO_02735 2.6e-64 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
IEDFMFCO_02736 9.1e-121 pnb C nitroreductase
IEDFMFCO_02737 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
IEDFMFCO_02738 1.1e-259 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
IEDFMFCO_02739 7.6e-95 K Bacterial regulatory proteins, tetR family
IEDFMFCO_02740 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IEDFMFCO_02741 6.8e-173 htrA 3.4.21.107 O serine protease
IEDFMFCO_02742 8.9e-158 vicX 3.1.26.11 S domain protein
IEDFMFCO_02743 2.9e-151 yycI S YycH protein
IEDFMFCO_02744 2e-244 yycH S YycH protein
IEDFMFCO_02745 0.0 vicK 2.7.13.3 T Histidine kinase
IEDFMFCO_02746 6.2e-131 K response regulator
IEDFMFCO_02748 1.7e-37
IEDFMFCO_02749 1.6e-31 cspA K Cold shock protein domain
IEDFMFCO_02750 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
IEDFMFCO_02751 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
IEDFMFCO_02752 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IEDFMFCO_02753 4.5e-143 S haloacid dehalogenase-like hydrolase
IEDFMFCO_02755 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
IEDFMFCO_02756 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IEDFMFCO_02757 8.1e-279 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
IEDFMFCO_02758 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
IEDFMFCO_02759 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IEDFMFCO_02760 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IEDFMFCO_02762 1.9e-276 E ABC transporter, substratebinding protein
IEDFMFCO_02764 5e-229 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IEDFMFCO_02765 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IEDFMFCO_02766 4.4e-225 yttB EGP Major facilitator Superfamily
IEDFMFCO_02767 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IEDFMFCO_02768 1.4e-67 rplI J Binds to the 23S rRNA
IEDFMFCO_02769 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IEDFMFCO_02770 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IEDFMFCO_02771 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IEDFMFCO_02772 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IEDFMFCO_02773 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEDFMFCO_02774 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEDFMFCO_02775 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IEDFMFCO_02776 5e-37 yaaA S S4 domain protein YaaA
IEDFMFCO_02777 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IEDFMFCO_02778 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IEDFMFCO_02779 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IEDFMFCO_02780 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEDFMFCO_02781 1e-309 E ABC transporter, substratebinding protein
IEDFMFCO_02782 9.3e-239 Q Imidazolonepropionase and related amidohydrolases
IEDFMFCO_02783 2.5e-130 jag S R3H domain protein
IEDFMFCO_02784 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IEDFMFCO_02785 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IEDFMFCO_02786 6.9e-93 S Cell surface protein
IEDFMFCO_02787 1.2e-159 S Bacterial protein of unknown function (DUF916)
IEDFMFCO_02789 9.8e-285
IEDFMFCO_02790 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IEDFMFCO_02792 2.8e-254 pepC 3.4.22.40 E aminopeptidase
IEDFMFCO_02793 2.4e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
IEDFMFCO_02794 1e-156 degV S DegV family
IEDFMFCO_02795 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
IEDFMFCO_02796 5.5e-144 tesE Q hydratase
IEDFMFCO_02797 1.9e-103 padC Q Phenolic acid decarboxylase
IEDFMFCO_02798 2.2e-99 padR K Virulence activator alpha C-term
IEDFMFCO_02799 2.7e-79 T Universal stress protein family
IEDFMFCO_02800 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IEDFMFCO_02801 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
IEDFMFCO_02802 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEDFMFCO_02803 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IEDFMFCO_02804 2.7e-160 rbsU U ribose uptake protein RbsU
IEDFMFCO_02805 1.5e-144 IQ NAD dependent epimerase/dehydratase family
IEDFMFCO_02806 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
IEDFMFCO_02807 1.1e-86 gutM K Glucitol operon activator protein (GutM)
IEDFMFCO_02808 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
IEDFMFCO_02809 1e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
IEDFMFCO_02810 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IEDFMFCO_02811 6.8e-156 lrp QT PucR C-terminal helix-turn-helix domain
IEDFMFCO_02812 2.2e-193 rliB K helix_turn_helix gluconate operon transcriptional repressor
IEDFMFCO_02813 0.0 yknV V ABC transporter
IEDFMFCO_02814 0.0 mdlA2 V ABC transporter
IEDFMFCO_02815 6.5e-156 K AraC-like ligand binding domain
IEDFMFCO_02816 0.0 3.2.1.52 GH20 G Glycosyl hydrolase family 20, catalytic domain
IEDFMFCO_02817 5.2e-181 U Binding-protein-dependent transport system inner membrane component
IEDFMFCO_02818 1.5e-161 lplC U Binding-protein-dependent transport system inner membrane component
IEDFMFCO_02819 2.8e-279 G Domain of unknown function (DUF3502)
IEDFMFCO_02820 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
IEDFMFCO_02821 4.1e-107 ypcB S integral membrane protein
IEDFMFCO_02822 0.0 yesM 2.7.13.3 T Histidine kinase
IEDFMFCO_02823 1e-139 K DeoR C terminal sensor domain
IEDFMFCO_02824 5.4e-178 rhaR K helix_turn_helix, arabinose operon control protein
IEDFMFCO_02825 7.8e-244 iolF EGP Major facilitator Superfamily
IEDFMFCO_02826 1.8e-286 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IEDFMFCO_02827 5e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
IEDFMFCO_02828 1.3e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
IEDFMFCO_02829 1.2e-165 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IEDFMFCO_02830 1e-125 S Membrane
IEDFMFCO_02831 1.1e-71 yueI S Protein of unknown function (DUF1694)
IEDFMFCO_02832 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IEDFMFCO_02833 8.7e-72 K Transcriptional regulator
IEDFMFCO_02834 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IEDFMFCO_02835 6.1e-202 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IEDFMFCO_02837 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
IEDFMFCO_02838 5.3e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
IEDFMFCO_02839 1.8e-12
IEDFMFCO_02840 8.7e-160 2.7.13.3 T GHKL domain
IEDFMFCO_02841 2.8e-134 K LytTr DNA-binding domain
IEDFMFCO_02842 1.9e-77 yneH 1.20.4.1 K ArsC family
IEDFMFCO_02843 1.1e-95 katA 1.11.1.6 C Belongs to the catalase family
IEDFMFCO_02844 3.9e-175 katA 1.11.1.6 C Belongs to the catalase family
IEDFMFCO_02845 9e-13 ytgB S Transglycosylase associated protein
IEDFMFCO_02846 3.6e-11
IEDFMFCO_02847 4.5e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
IEDFMFCO_02848 4.2e-70 S Pyrimidine dimer DNA glycosylase
IEDFMFCO_02849 4.9e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
IEDFMFCO_02850 1.1e-121 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IEDFMFCO_02851 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
IEDFMFCO_02852 5.2e-156 nanK GK ROK family
IEDFMFCO_02853 1.9e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
IEDFMFCO_02854 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IEDFMFCO_02855 2.6e-272 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEDFMFCO_02856 5.2e-161 I alpha/beta hydrolase fold
IEDFMFCO_02857 1.3e-164 I alpha/beta hydrolase fold
IEDFMFCO_02858 3.7e-72 yueI S Protein of unknown function (DUF1694)
IEDFMFCO_02859 7.4e-136 K Helix-turn-helix domain, rpiR family
IEDFMFCO_02860 6.8e-206 araR K Transcriptional regulator
IEDFMFCO_02861 5.5e-256 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IEDFMFCO_02862 1.9e-305 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
IEDFMFCO_02863 1e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IEDFMFCO_02864 1.3e-265 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IEDFMFCO_02865 9.6e-103 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IEDFMFCO_02866 8.1e-10 yueI S Protein of unknown function (DUF1694)
IEDFMFCO_02867 1.5e-49 yueI S Protein of unknown function (DUF1694)
IEDFMFCO_02868 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IEDFMFCO_02869 5.2e-123 K DeoR C terminal sensor domain
IEDFMFCO_02870 8.1e-79 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEDFMFCO_02871 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IEDFMFCO_02872 1.1e-231 gatC G PTS system sugar-specific permease component
IEDFMFCO_02873 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
IEDFMFCO_02874 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
IEDFMFCO_02875 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEDFMFCO_02876 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEDFMFCO_02877 6.3e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
IEDFMFCO_02878 6.4e-241 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IEDFMFCO_02879 7e-113 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IEDFMFCO_02880 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IEDFMFCO_02881 1.3e-145 yxeH S hydrolase
IEDFMFCO_02882 2.9e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IEDFMFCO_02884 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IEDFMFCO_02885 1.5e-269 G Major Facilitator
IEDFMFCO_02886 2.1e-174 K Transcriptional regulator, LacI family
IEDFMFCO_02887 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
IEDFMFCO_02888 3.8e-159 licT K CAT RNA binding domain
IEDFMFCO_02889 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
IEDFMFCO_02890 9.4e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_02891 3.4e-293 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_02892 1.3e-154 licT K CAT RNA binding domain
IEDFMFCO_02893 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
IEDFMFCO_02894 1e-292 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFMFCO_02895 1.7e-212 S Bacterial protein of unknown function (DUF871)
IEDFMFCO_02896 1.9e-161 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
IEDFMFCO_02897 3e-165 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IEDFMFCO_02898 2.4e-248 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFMFCO_02899 1.2e-134 K UTRA domain
IEDFMFCO_02900 1.8e-155 estA S Putative esterase
IEDFMFCO_02901 7.6e-64
IEDFMFCO_02902 6.7e-210 ydiN G Major Facilitator Superfamily
IEDFMFCO_02903 3.4e-163 K Transcriptional regulator, LysR family
IEDFMFCO_02904 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IEDFMFCO_02905 1.2e-214 ydiM G Transporter
IEDFMFCO_02906 1.9e-130 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IEDFMFCO_02907 8.2e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IEDFMFCO_02908 0.0 1.3.5.4 C FAD binding domain
IEDFMFCO_02909 2.4e-65 S pyridoxamine 5-phosphate
IEDFMFCO_02910 2.6e-194 C Aldo keto reductase family protein
IEDFMFCO_02911 1.1e-173 galR K Transcriptional regulator
IEDFMFCO_02912 4.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IEDFMFCO_02913 0.0 lacS G Transporter
IEDFMFCO_02914 0.0 rafA 3.2.1.22 G alpha-galactosidase
IEDFMFCO_02915 8.3e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IEDFMFCO_02916 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IEDFMFCO_02917 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IEDFMFCO_02918 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IEDFMFCO_02919 5e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IEDFMFCO_02920 2.6e-07 galR K Transcriptional regulator
IEDFMFCO_02921 3.3e-152 galR K Transcriptional regulator
IEDFMFCO_02922 1.6e-76 K Helix-turn-helix XRE-family like proteins
IEDFMFCO_02923 5.1e-110 fic D Fic/DOC family
IEDFMFCO_02924 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
IEDFMFCO_02925 8.6e-232 EGP Major facilitator Superfamily
IEDFMFCO_02926 5.2e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IEDFMFCO_02927 1.6e-230 mdtH P Sugar (and other) transporter
IEDFMFCO_02928 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IEDFMFCO_02929 1.6e-188 lacR K Transcriptional regulator
IEDFMFCO_02930 0.0 lacA 3.2.1.23 G -beta-galactosidase
IEDFMFCO_02931 0.0 lacS G Transporter
IEDFMFCO_02932 6.9e-251 brnQ U Component of the transport system for branched-chain amino acids
IEDFMFCO_02933 0.0 ubiB S ABC1 family
IEDFMFCO_02934 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
IEDFMFCO_02935 2.4e-220 3.1.3.1 S associated with various cellular activities
IEDFMFCO_02936 2.2e-246 S Putative metallopeptidase domain
IEDFMFCO_02937 1.5e-49
IEDFMFCO_02938 1.2e-103 K Bacterial regulatory proteins, tetR family
IEDFMFCO_02939 1e-44
IEDFMFCO_02940 2.3e-99 S WxL domain surface cell wall-binding
IEDFMFCO_02941 1.5e-118 S WxL domain surface cell wall-binding
IEDFMFCO_02942 6.1e-164 S Cell surface protein
IEDFMFCO_02943 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IEDFMFCO_02944 1.3e-262 nox C NADH oxidase
IEDFMFCO_02945 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IEDFMFCO_02946 2.9e-106
IEDFMFCO_02947 1.4e-117 S Domain of unknown function (DUF4811)
IEDFMFCO_02948 7e-270 lmrB EGP Major facilitator Superfamily
IEDFMFCO_02949 1.7e-84 merR K MerR HTH family regulatory protein
IEDFMFCO_02950 2.6e-58
IEDFMFCO_02951 2e-120 sirR K iron dependent repressor
IEDFMFCO_02952 6e-31 cspC K Cold shock protein
IEDFMFCO_02953 1.5e-130 thrE S Putative threonine/serine exporter
IEDFMFCO_02954 2.2e-76 S Threonine/Serine exporter, ThrE
IEDFMFCO_02955 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IEDFMFCO_02956 2.3e-119 lssY 3.6.1.27 I phosphatase
IEDFMFCO_02957 2e-154 I alpha/beta hydrolase fold
IEDFMFCO_02958 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
IEDFMFCO_02959 4.2e-92 K Transcriptional regulator
IEDFMFCO_02960 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IEDFMFCO_02961 1.5e-264 lysP E amino acid
IEDFMFCO_02962 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IEDFMFCO_02963 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IEDFMFCO_02964 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IEDFMFCO_02972 6.9e-78 ctsR K Belongs to the CtsR family
IEDFMFCO_02973 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IEDFMFCO_02974 7.4e-109 K Bacterial regulatory proteins, tetR family
IEDFMFCO_02975 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEDFMFCO_02976 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEDFMFCO_02977 7.8e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IEDFMFCO_02978 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IEDFMFCO_02979 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IEDFMFCO_02980 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IEDFMFCO_02981 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IEDFMFCO_02982 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IEDFMFCO_02983 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IEDFMFCO_02984 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IEDFMFCO_02985 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IEDFMFCO_02986 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IEDFMFCO_02987 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IEDFMFCO_02988 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IEDFMFCO_02989 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IEDFMFCO_02990 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
IEDFMFCO_02991 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IEDFMFCO_02992 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IEDFMFCO_02993 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IEDFMFCO_02994 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IEDFMFCO_02995 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IEDFMFCO_02996 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IEDFMFCO_02997 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IEDFMFCO_02998 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IEDFMFCO_02999 2.2e-24 rpmD J Ribosomal protein L30
IEDFMFCO_03000 6.3e-70 rplO J Binds to the 23S rRNA
IEDFMFCO_03001 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IEDFMFCO_03002 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IEDFMFCO_03003 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IEDFMFCO_03004 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IEDFMFCO_03005 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IEDFMFCO_03006 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEDFMFCO_03007 2.1e-61 rplQ J Ribosomal protein L17
IEDFMFCO_03008 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IEDFMFCO_03009 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
IEDFMFCO_03010 1.4e-86 ynhH S NusG domain II
IEDFMFCO_03011 0.0 ndh 1.6.99.3 C NADH dehydrogenase
IEDFMFCO_03012 3.9e-141 cad S FMN_bind
IEDFMFCO_03013 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IEDFMFCO_03014 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEDFMFCO_03015 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEDFMFCO_03016 4.7e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEDFMFCO_03017 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IEDFMFCO_03018 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IEDFMFCO_03019 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IEDFMFCO_03020 4e-164 degV S Uncharacterised protein, DegV family COG1307
IEDFMFCO_03021 1.7e-183 ywhK S Membrane
IEDFMFCO_03022 4.2e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IEDFMFCO_03023 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IEDFMFCO_03024 8.3e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IEDFMFCO_03025 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
IEDFMFCO_03026 4.9e-196 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IEDFMFCO_03027 1.5e-220 P Sodium:sulfate symporter transmembrane region
IEDFMFCO_03028 4.1e-53 yitW S Iron-sulfur cluster assembly protein
IEDFMFCO_03029 5.4e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
IEDFMFCO_03030 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
IEDFMFCO_03031 1.7e-198 K Helix-turn-helix domain
IEDFMFCO_03032 2.4e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IEDFMFCO_03033 4.5e-132 mntB 3.6.3.35 P ABC transporter
IEDFMFCO_03034 4.8e-141 mtsB U ABC 3 transport family
IEDFMFCO_03035 2.3e-173 sitA P Belongs to the bacterial solute-binding protein 9 family
IEDFMFCO_03036 3.1e-50
IEDFMFCO_03037 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IEDFMFCO_03038 2.2e-260 citP P Sodium:sulfate symporter transmembrane region
IEDFMFCO_03039 2.9e-179 citR K sugar-binding domain protein
IEDFMFCO_03040 5.1e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IEDFMFCO_03041 4.8e-188 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IEDFMFCO_03042 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
IEDFMFCO_03043 5.5e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IEDFMFCO_03044 4.6e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IEDFMFCO_03046 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IEDFMFCO_03047 2.7e-263 frdC 1.3.5.4 C FAD binding domain
IEDFMFCO_03048 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IEDFMFCO_03049 1.6e-160 mleR K LysR family transcriptional regulator

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)