ORF_ID e_value Gene_name EC_number CAZy COGs Description
APOBLMKD_00005 7.8e-08
APOBLMKD_00013 1.6e-08
APOBLMKD_00017 9e-21 C Na+/H+ antiporter family
APOBLMKD_00018 2.4e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
APOBLMKD_00019 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
APOBLMKD_00020 9e-264 ygaK C Berberine and berberine like
APOBLMKD_00022 2e-231 oppA5 E PFAM extracellular solute-binding protein family 5
APOBLMKD_00023 5.4e-138 appB P Binding-protein-dependent transport system inner membrane component
APOBLMKD_00024 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOBLMKD_00025 1.5e-135 oppD3 P Belongs to the ABC transporter superfamily
APOBLMKD_00026 4e-133 oppF3 E Belongs to the ABC transporter superfamily
APOBLMKD_00027 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
APOBLMKD_00028 7.3e-180 S Amidohydrolase
APOBLMKD_00029 1.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
APOBLMKD_00030 4.4e-167 ssuA M Sulfonate ABC transporter
APOBLMKD_00031 7e-142 ssuC P ABC transporter (permease)
APOBLMKD_00032 2.5e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
APOBLMKD_00033 1.6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APOBLMKD_00034 8.6e-81 ygaO
APOBLMKD_00035 4.8e-23 K Transcriptional regulator
APOBLMKD_00037 9.4e-107 yhzB S B3/4 domain
APOBLMKD_00038 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APOBLMKD_00039 1.4e-173 yhbB S Putative amidase domain
APOBLMKD_00040 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APOBLMKD_00041 3e-108 yhbD K Protein of unknown function (DUF4004)
APOBLMKD_00042 8.9e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
APOBLMKD_00043 1e-61 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
APOBLMKD_00045 0.0 prkA T Ser protein kinase
APOBLMKD_00046 3.9e-215 yhbH S Belongs to the UPF0229 family
APOBLMKD_00047 4.6e-74 yhbI K DNA-binding transcription factor activity
APOBLMKD_00048 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
APOBLMKD_00049 8.4e-285 yhcA EGP Major facilitator Superfamily
APOBLMKD_00050 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
APOBLMKD_00051 3.8e-55 yhcC
APOBLMKD_00052 1.3e-52
APOBLMKD_00053 2.8e-61 yhcF K Transcriptional regulator
APOBLMKD_00054 1.3e-123 yhcG V ABC transporter, ATP-binding protein
APOBLMKD_00055 1.2e-166 yhcH V ABC transporter, ATP-binding protein
APOBLMKD_00056 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APOBLMKD_00057 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
APOBLMKD_00058 1.7e-143 metQ M Belongs to the nlpA lipoprotein family
APOBLMKD_00059 6.7e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
APOBLMKD_00060 1.1e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOBLMKD_00061 6.5e-54 yhcM
APOBLMKD_00062 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APOBLMKD_00063 3.2e-159 yhcP
APOBLMKD_00064 8.4e-114 yhcQ M Spore coat protein
APOBLMKD_00065 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
APOBLMKD_00066 7.1e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
APOBLMKD_00067 1.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APOBLMKD_00068 1.3e-69 yhcU S Family of unknown function (DUF5365)
APOBLMKD_00069 3.8e-67 yhcV S COG0517 FOG CBS domain
APOBLMKD_00070 1.9e-124 yhcW 5.4.2.6 S hydrolase
APOBLMKD_00071 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APOBLMKD_00072 9.3e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOBLMKD_00073 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
APOBLMKD_00074 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
APOBLMKD_00075 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APOBLMKD_00076 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
APOBLMKD_00077 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
APOBLMKD_00078 8.5e-70 yhcY 2.7.13.3 T Histidine kinase
APOBLMKD_00079 1.6e-36 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOBLMKD_00080 4.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
APOBLMKD_00081 2.5e-39 yhdB S YhdB-like protein
APOBLMKD_00082 1.1e-53 yhdC S Protein of unknown function (DUF3889)
APOBLMKD_00083 5.4e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APOBLMKD_00084 1.6e-73 nsrR K Transcriptional regulator
APOBLMKD_00085 1.5e-254 ygxB M Conserved TM helix
APOBLMKD_00086 1.8e-270 ycgB S Stage V sporulation protein R
APOBLMKD_00087 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
APOBLMKD_00088 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APOBLMKD_00089 1.3e-162 citR K Transcriptional regulator
APOBLMKD_00090 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
APOBLMKD_00091 3.9e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_00092 1.2e-250 yhdG E amino acid
APOBLMKD_00093 2.9e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APOBLMKD_00094 8.1e-45 yhdK S Sigma-M inhibitor protein
APOBLMKD_00095 1.3e-201 yhdL S Sigma factor regulator N-terminal
APOBLMKD_00096 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
APOBLMKD_00097 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APOBLMKD_00098 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
APOBLMKD_00099 2.8e-70 cueR K transcriptional
APOBLMKD_00100 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
APOBLMKD_00101 4.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APOBLMKD_00102 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
APOBLMKD_00103 7.2e-51 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APOBLMKD_00104 3.3e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APOBLMKD_00105 3.6e-126 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APOBLMKD_00107 3.5e-205 yhdY M Mechanosensitive ion channel
APOBLMKD_00108 1.1e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
APOBLMKD_00109 1.1e-155 yheN G deacetylase
APOBLMKD_00110 7.7e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
APOBLMKD_00111 3e-87 pksA K Transcriptional regulator
APOBLMKD_00112 1.8e-93 ymcC S Membrane
APOBLMKD_00113 6.2e-85 T universal stress protein
APOBLMKD_00115 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
APOBLMKD_00116 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
APOBLMKD_00117 1.6e-111 yheG GM NAD(P)H-binding
APOBLMKD_00119 1.3e-28 sspB S spore protein
APOBLMKD_00120 1.7e-36 yheE S Family of unknown function (DUF5342)
APOBLMKD_00121 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
APOBLMKD_00122 3.4e-213 yheC HJ YheC/D like ATP-grasp
APOBLMKD_00123 3.6e-205 yheB S Belongs to the UPF0754 family
APOBLMKD_00124 4.4e-53 yheA S Belongs to the UPF0342 family
APOBLMKD_00125 1.3e-199 yhaZ L DNA alkylation repair enzyme
APOBLMKD_00126 1.8e-156 yhaX S haloacid dehalogenase-like hydrolase
APOBLMKD_00127 7.9e-293 hemZ H coproporphyrinogen III oxidase
APOBLMKD_00128 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
APOBLMKD_00129 1.8e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
APOBLMKD_00130 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
APOBLMKD_00132 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
APOBLMKD_00133 2.8e-14 S YhzD-like protein
APOBLMKD_00134 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
APOBLMKD_00135 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
APOBLMKD_00136 2.1e-235 yhaO L DNA repair exonuclease
APOBLMKD_00137 0.0 yhaN L AAA domain
APOBLMKD_00138 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
APOBLMKD_00139 1.8e-31 yhaL S Sporulation protein YhaL
APOBLMKD_00140 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APOBLMKD_00141 7e-95 yhaK S Putative zincin peptidase
APOBLMKD_00142 9.9e-55 yhaI S Protein of unknown function (DUF1878)
APOBLMKD_00143 8.6e-113 hpr K Negative regulator of protease production and sporulation
APOBLMKD_00144 6.2e-39 yhaH S YtxH-like protein
APOBLMKD_00145 2e-17
APOBLMKD_00146 1.4e-76 trpP S Tryptophan transporter TrpP
APOBLMKD_00147 2.3e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APOBLMKD_00148 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
APOBLMKD_00149 1.1e-135 ecsA V transporter (ATP-binding protein)
APOBLMKD_00150 4.2e-220 ecsB U ABC transporter
APOBLMKD_00151 4e-122 ecsC S EcsC protein family
APOBLMKD_00152 2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
APOBLMKD_00153 6.2e-244 yhfA C membrane
APOBLMKD_00154 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
APOBLMKD_00155 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APOBLMKD_00156 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
APOBLMKD_00157 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
APOBLMKD_00158 2.7e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
APOBLMKD_00159 3.2e-101 yhgD K Transcriptional regulator
APOBLMKD_00160 2.5e-245 yhgE S YhgE Pip N-terminal domain protein
APOBLMKD_00161 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APOBLMKD_00163 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
APOBLMKD_00164 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOBLMKD_00165 4.9e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
APOBLMKD_00166 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
APOBLMKD_00167 5.5e-110 yhfK GM NmrA-like family
APOBLMKD_00168 2.4e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
APOBLMKD_00169 1.1e-63 yhfM
APOBLMKD_00170 1.1e-234 yhfN 3.4.24.84 O Peptidase M48
APOBLMKD_00171 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
APOBLMKD_00172 3.1e-148 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
APOBLMKD_00173 2.6e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
APOBLMKD_00174 2.2e-196 vraB 2.3.1.9 I Belongs to the thiolase family
APOBLMKD_00175 2.5e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
APOBLMKD_00176 1.8e-88 bioY S BioY family
APOBLMKD_00177 3.1e-197 hemAT NT chemotaxis protein
APOBLMKD_00178 1.7e-295 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
APOBLMKD_00179 1.2e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_00180 5.4e-31 yhzC S IDEAL
APOBLMKD_00181 1.9e-109 comK K Competence transcription factor
APOBLMKD_00182 6.8e-65 frataxin S Domain of unknown function (DU1801)
APOBLMKD_00183 4.9e-63 frataxin S Domain of unknown function (DU1801)
APOBLMKD_00184 8.7e-125 yrpD S Domain of unknown function, YrpD
APOBLMKD_00185 1.6e-42 yhjA S Excalibur calcium-binding domain
APOBLMKD_00186 3.3e-47 S Belongs to the UPF0145 family
APOBLMKD_00187 1.5e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOBLMKD_00188 3.1e-27 yhjC S Protein of unknown function (DUF3311)
APOBLMKD_00189 1.7e-60 yhjD
APOBLMKD_00190 2.6e-109 yhjE S SNARE associated Golgi protein
APOBLMKD_00191 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
APOBLMKD_00193 4.1e-270 yhjG CH FAD binding domain
APOBLMKD_00194 2.9e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_00195 1.5e-187 abrB S membrane
APOBLMKD_00196 3e-202 blt EGP Major facilitator Superfamily
APOBLMKD_00197 1.9e-107 K QacR-like protein, C-terminal region
APOBLMKD_00198 1.6e-88 yhjR S Rubrerythrin
APOBLMKD_00199 2.5e-119 ydfS S Protein of unknown function (DUF421)
APOBLMKD_00200 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
APOBLMKD_00201 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
APOBLMKD_00202 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APOBLMKD_00203 0.0 sbcC L COG0419 ATPase involved in DNA repair
APOBLMKD_00204 1.3e-50 yisB V COG1403 Restriction endonuclease
APOBLMKD_00205 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
APOBLMKD_00206 1.1e-63 gerPE S Spore germination protein GerPE
APOBLMKD_00207 3.1e-23 gerPD S Spore germination protein
APOBLMKD_00208 1.4e-62 gerPC S Spore germination protein
APOBLMKD_00209 1.8e-34 gerPB S cell differentiation
APOBLMKD_00210 8.4e-34 gerPA S Spore germination protein
APOBLMKD_00211 4.8e-07 yisI S Spo0E like sporulation regulatory protein
APOBLMKD_00212 7.8e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
APOBLMKD_00213 3.2e-59 yisL S UPF0344 protein
APOBLMKD_00214 3.4e-97 yisN S Protein of unknown function (DUF2777)
APOBLMKD_00215 0.0 asnO 6.3.5.4 E Asparagine synthase
APOBLMKD_00216 3.8e-131 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
APOBLMKD_00217 1.9e-245 yisQ V Mate efflux family protein
APOBLMKD_00218 1.2e-157 yisR K Transcriptional regulator
APOBLMKD_00219 7.8e-143 purR K helix_turn _helix lactose operon repressor
APOBLMKD_00220 2.2e-153 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
APOBLMKD_00221 3.4e-83 yisT S DinB family
APOBLMKD_00222 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
APOBLMKD_00223 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
APOBLMKD_00224 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
APOBLMKD_00225 6.6e-55 yajQ S Belongs to the UPF0234 family
APOBLMKD_00226 7.6e-160 cvfB S protein conserved in bacteria
APOBLMKD_00227 1.1e-170 yufN S ABC transporter substrate-binding protein PnrA-like
APOBLMKD_00228 7.4e-110 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
APOBLMKD_00230 1.3e-156 yitS S protein conserved in bacteria
APOBLMKD_00231 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
APOBLMKD_00232 1.2e-79 ipi S Intracellular proteinase inhibitor
APOBLMKD_00233 4.4e-26 S Protein of unknown function (DUF3813)
APOBLMKD_00234 3.5e-07
APOBLMKD_00235 1.1e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
APOBLMKD_00236 9e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
APOBLMKD_00237 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
APOBLMKD_00238 5.4e-74 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
APOBLMKD_00239 1.2e-269 yitY C D-arabinono-1,4-lactone oxidase
APOBLMKD_00240 1.2e-89 norB G Major Facilitator Superfamily
APOBLMKD_00241 4.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
APOBLMKD_00242 1.1e-223 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
APOBLMKD_00243 7.8e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
APOBLMKD_00244 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
APOBLMKD_00245 1.5e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APOBLMKD_00246 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
APOBLMKD_00247 1.3e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APOBLMKD_00248 1.2e-27 yjzC S YjzC-like protein
APOBLMKD_00249 2.8e-22 yjzD S Protein of unknown function (DUF2929)
APOBLMKD_00250 3.2e-138 yjaU I carboxylic ester hydrolase activity
APOBLMKD_00251 2e-103 yjaV
APOBLMKD_00252 2.7e-165 med S Transcriptional activator protein med
APOBLMKD_00253 1.1e-26 comZ S ComZ
APOBLMKD_00254 1e-31 yjzB
APOBLMKD_00255 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APOBLMKD_00256 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APOBLMKD_00257 5.6e-149 yjaZ O Zn-dependent protease
APOBLMKD_00258 4.8e-182 appD P Belongs to the ABC transporter superfamily
APOBLMKD_00259 5.9e-188 appF E Belongs to the ABC transporter superfamily
APOBLMKD_00260 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
APOBLMKD_00261 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOBLMKD_00262 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOBLMKD_00263 1.2e-145 yjbA S Belongs to the UPF0736 family
APOBLMKD_00264 3.4e-39 S COG NOG14552 non supervised orthologous group
APOBLMKD_00265 1.6e-219 glcP G Major Facilitator Superfamily
APOBLMKD_00266 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOBLMKD_00267 2.5e-175 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
APOBLMKD_00268 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
APOBLMKD_00269 1.3e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
APOBLMKD_00270 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
APOBLMKD_00271 7.1e-109 ybbA S Putative esterase
APOBLMKD_00272 6.1e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_00273 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_00274 2e-172 feuA P Iron-uptake system-binding protein
APOBLMKD_00275 3.9e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
APOBLMKD_00276 1.8e-234 ybbC 3.2.1.52 S protein conserved in bacteria
APOBLMKD_00277 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
APOBLMKD_00278 6.8e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
APOBLMKD_00279 2.7e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOBLMKD_00280 3.4e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APOBLMKD_00281 7.7e-85 ybbJ J acetyltransferase
APOBLMKD_00282 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
APOBLMKD_00285 6e-70 ohrB O Organic hydroperoxide resistance protein
APOBLMKD_00286 1.8e-72 ohrR K COG1846 Transcriptional regulators
APOBLMKD_00287 1.2e-68 ohrA O Organic hydroperoxide resistance protein
APOBLMKD_00288 3.8e-224 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APOBLMKD_00289 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APOBLMKD_00290 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
APOBLMKD_00291 2.9e-48 ykkD P Multidrug resistance protein
APOBLMKD_00292 1.4e-51 ykkC P Multidrug resistance protein
APOBLMKD_00293 1.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APOBLMKD_00294 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
APOBLMKD_00295 5.5e-158 ykgA E Amidinotransferase
APOBLMKD_00296 1.5e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
APOBLMKD_00297 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
APOBLMKD_00298 8.6e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APOBLMKD_00299 5.9e-197 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APOBLMKD_00300 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
APOBLMKD_00301 0.0 dppE E ABC transporter substrate-binding protein
APOBLMKD_00302 2.9e-190 dppD P Belongs to the ABC transporter superfamily
APOBLMKD_00303 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOBLMKD_00304 5.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOBLMKD_00305 2.7e-154 dppA E D-aminopeptidase
APOBLMKD_00306 2.8e-277 yubD P Major Facilitator Superfamily
APOBLMKD_00307 4e-203 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APOBLMKD_00309 7.1e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APOBLMKD_00310 2e-305 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APOBLMKD_00311 8.2e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
APOBLMKD_00312 1.1e-242 steT E amino acid
APOBLMKD_00313 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
APOBLMKD_00314 5.8e-175 pit P phosphate transporter
APOBLMKD_00315 5.9e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
APOBLMKD_00316 8.7e-23 spoIISB S Stage II sporulation protein SB
APOBLMKD_00317 1.4e-169 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOBLMKD_00318 1.3e-38 xhlB S SPP1 phage holin
APOBLMKD_00319 9.6e-37 xhlA S Haemolysin XhlA
APOBLMKD_00320 8.1e-137 xepA
APOBLMKD_00321 1.6e-28 xkdX
APOBLMKD_00323 6.4e-91
APOBLMKD_00324 1.2e-26
APOBLMKD_00325 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
APOBLMKD_00326 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
APOBLMKD_00327 4.2e-58 xkdS S Protein of unknown function (DUF2634)
APOBLMKD_00328 7.2e-32 xkdR S Protein of unknown function (DUF2577)
APOBLMKD_00329 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
APOBLMKD_00330 6.6e-111 xkdP S Lysin motif
APOBLMKD_00331 1e-203 xkdO L Transglycosylase SLT domain
APOBLMKD_00332 3.4e-19
APOBLMKD_00333 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
APOBLMKD_00334 2e-74 xkdM S Phage tail tube protein
APOBLMKD_00335 1.6e-226 xkdK S Phage tail sheath C-terminal domain
APOBLMKD_00336 8.2e-15
APOBLMKD_00337 3.2e-56 xkdJ
APOBLMKD_00338 4.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
APOBLMKD_00339 5.5e-43 yqbH S Domain of unknown function (DUF3599)
APOBLMKD_00340 3.3e-46 yqbG S Protein of unknown function (DUF3199)
APOBLMKD_00341 4.6e-158 xkdG S Phage capsid family
APOBLMKD_00342 9.8e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
APOBLMKD_00343 5.1e-241 yqbA S portal protein
APOBLMKD_00344 3.6e-209 xtmB S phage terminase, large subunit
APOBLMKD_00345 8.9e-110 xtmA L phage terminase small subunit
APOBLMKD_00346 3.1e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
APOBLMKD_00347 2e-10 yqaO S Phage-like element PBSX protein XtrA
APOBLMKD_00350 8.8e-150 xkdC L Bacterial dnaA protein
APOBLMKD_00352 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
APOBLMKD_00353 2.9e-110 xkdA E IrrE N-terminal-like domain
APOBLMKD_00355 3.9e-110 yjqB S phage-related replication protein
APOBLMKD_00356 2.3e-60 yjqA S Bacterial PH domain
APOBLMKD_00357 6.5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
APOBLMKD_00359 4.9e-215 S response regulator aspartate phosphatase
APOBLMKD_00360 3.1e-78 yjoA S DinB family
APOBLMKD_00361 1.5e-130 MA20_18170 S membrane transporter protein
APOBLMKD_00362 3.4e-204 salB V Domain of unknown function (DUF4135)
APOBLMKD_00365 2.3e-221 lanT 3.6.3.27 V Peptidase C39 family
APOBLMKD_00366 8.2e-300 lcnDR2 V Lanthionine synthetase C-like protein
APOBLMKD_00368 5.4e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOBLMKD_00369 2.2e-46 narQ 2.7.13.3 T Histidine kinase
APOBLMKD_00371 1.4e-64 S ABC-2 family transporter protein
APOBLMKD_00372 8.5e-104 V ABC transporter, ATP-binding protein
APOBLMKD_00373 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
APOBLMKD_00374 4e-87 T Transcriptional regulatory protein, C terminal
APOBLMKD_00375 5.4e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
APOBLMKD_00376 1.3e-276 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
APOBLMKD_00377 7e-181 exuR K transcriptional
APOBLMKD_00378 9.6e-253 yjmB G symporter YjmB
APOBLMKD_00379 4.8e-276 uxaC 5.3.1.12 G glucuronate isomerase
APOBLMKD_00380 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
APOBLMKD_00381 7e-66 yjlC S Protein of unknown function (DUF1641)
APOBLMKD_00382 1.8e-89 yjlB S Cupin domain
APOBLMKD_00383 4.4e-175 yjlA EG Putative multidrug resistance efflux transporter
APOBLMKD_00384 1e-128 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
APOBLMKD_00385 2.1e-124 ybbM S transport system, permease component
APOBLMKD_00386 5.6e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APOBLMKD_00387 6.8e-29
APOBLMKD_00388 1e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APOBLMKD_00389 4.4e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
APOBLMKD_00390 1.6e-91 yjgD S Protein of unknown function (DUF1641)
APOBLMKD_00391 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
APOBLMKD_00392 1.3e-99 yjgB S Domain of unknown function (DUF4309)
APOBLMKD_00393 2.3e-66 T PhoQ Sensor
APOBLMKD_00394 3.7e-21 yjfB S Putative motility protein
APOBLMKD_00395 8.1e-106 yhiD S MgtC SapB transporter
APOBLMKD_00396 1.3e-51 K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_00397 2e-34
APOBLMKD_00398 1.9e-121 5.4.2.6 S Haloacid dehalogenase-like hydrolase
APOBLMKD_00399 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
APOBLMKD_00400 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
APOBLMKD_00401 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
APOBLMKD_00402 3.7e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APOBLMKD_00403 6.3e-213 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APOBLMKD_00404 2.1e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
APOBLMKD_00405 1.9e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
APOBLMKD_00406 5e-220 ganA 3.2.1.89 G arabinogalactan
APOBLMKD_00407 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_00408 1.7e-249 yfjF EGP Belongs to the major facilitator superfamily
APOBLMKD_00409 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
APOBLMKD_00410 1.5e-161 bla 3.5.2.6 V beta-lactamase
APOBLMKD_00411 1.5e-57 E Glyoxalase-like domain
APOBLMKD_00413 1.9e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
APOBLMKD_00414 7.1e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
APOBLMKD_00415 6.7e-246 yoeA V MATE efflux family protein
APOBLMKD_00416 2.9e-96 yoeB S IseA DL-endopeptidase inhibitor
APOBLMKD_00418 3.5e-97 L Integrase
APOBLMKD_00419 1.8e-34 yoeD G Helix-turn-helix domain
APOBLMKD_00420 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
APOBLMKD_00421 5.2e-199 ybcL EGP Major facilitator Superfamily
APOBLMKD_00422 3.9e-50 ybzH K Helix-turn-helix domain
APOBLMKD_00423 1.5e-14 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APOBLMKD_00424 1.2e-152 gltR1 K Transcriptional regulator
APOBLMKD_00425 4.8e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
APOBLMKD_00426 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
APOBLMKD_00427 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
APOBLMKD_00428 4.5e-150 gltC K Transcriptional regulator
APOBLMKD_00429 6.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APOBLMKD_00430 6.3e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APOBLMKD_00431 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
APOBLMKD_00432 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
APOBLMKD_00433 8.3e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APOBLMKD_00434 1.9e-133 yoxB
APOBLMKD_00435 7.4e-204 yoaB EGP Major facilitator Superfamily
APOBLMKD_00436 1.1e-267 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
APOBLMKD_00437 9.6e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOBLMKD_00438 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOBLMKD_00441 1.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_00442 2.5e-43
APOBLMKD_00443 2.9e-131 IQ Enoyl-(Acyl carrier protein) reductase
APOBLMKD_00444 8.5e-60 ykvN K Transcriptional regulator
APOBLMKD_00445 1.1e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
APOBLMKD_00446 1.6e-131 yobQ K helix_turn_helix, arabinose operon control protein
APOBLMKD_00447 4.5e-92 yobS K Transcriptional regulator
APOBLMKD_00448 3.6e-134 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
APOBLMKD_00449 7.1e-92 yobW
APOBLMKD_00450 8.4e-54 czrA K transcriptional
APOBLMKD_00451 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APOBLMKD_00452 3.6e-91 yozB S membrane
APOBLMKD_00453 8.9e-139 yocB J Protein required for attachment to host cells
APOBLMKD_00454 1.6e-93 yocC
APOBLMKD_00455 2.4e-186 yocD 3.4.17.13 V peptidase S66
APOBLMKD_00457 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
APOBLMKD_00458 0.0 recQ 3.6.4.12 L DNA helicase
APOBLMKD_00459 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APOBLMKD_00461 2.3e-55 dksA T general stress protein
APOBLMKD_00462 1.7e-09 yocL
APOBLMKD_00463 7.5e-09
APOBLMKD_00464 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
APOBLMKD_00465 3.8e-44 yozN
APOBLMKD_00466 8.5e-37 yocN
APOBLMKD_00467 2.4e-56 yozO S Bacterial PH domain
APOBLMKD_00469 3.6e-31 yozC
APOBLMKD_00470 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
APOBLMKD_00471 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
APOBLMKD_00472 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
APOBLMKD_00473 7.4e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APOBLMKD_00474 2.5e-159 yocS S -transporter
APOBLMKD_00475 1.1e-138 S Metallo-beta-lactamase superfamily
APOBLMKD_00476 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
APOBLMKD_00477 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
APOBLMKD_00478 0.0 yojO P Von Willebrand factor
APOBLMKD_00479 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
APOBLMKD_00480 2.9e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
APOBLMKD_00481 9.5e-228 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APOBLMKD_00482 5.8e-222 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
APOBLMKD_00483 1.7e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APOBLMKD_00485 6.1e-236 norM V Multidrug efflux pump
APOBLMKD_00486 2.2e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APOBLMKD_00487 5.6e-126 yojG S deacetylase
APOBLMKD_00488 3.7e-60 yojF S Protein of unknown function (DUF1806)
APOBLMKD_00489 4.9e-23
APOBLMKD_00490 1.1e-161 rarD S -transporter
APOBLMKD_00491 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
APOBLMKD_00493 2.3e-66 yodA S tautomerase
APOBLMKD_00494 3.9e-68 yoaQ S Evidence 4 Homologs of previously reported genes of
APOBLMKD_00495 3e-56 yodB K transcriptional
APOBLMKD_00496 4.5e-106 yodC C nitroreductase
APOBLMKD_00497 5.7e-109 mhqD S Carboxylesterase
APOBLMKD_00498 5e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
APOBLMKD_00499 1.4e-19 S Protein of unknown function (DUF3311)
APOBLMKD_00500 3e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOBLMKD_00501 1e-276 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
APOBLMKD_00502 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APOBLMKD_00503 2.6e-132 yydK K Transcriptional regulator
APOBLMKD_00504 7.9e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
APOBLMKD_00505 2.8e-128 yodH Q Methyltransferase
APOBLMKD_00506 1.9e-21 yodI
APOBLMKD_00507 2.3e-121 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
APOBLMKD_00508 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
APOBLMKD_00510 3.3e-55 yodL S YodL-like
APOBLMKD_00511 2.3e-102 yodM 3.6.1.27 I Acid phosphatase homologues
APOBLMKD_00512 6.2e-24 yozD S YozD-like protein
APOBLMKD_00514 1.7e-125 yodN
APOBLMKD_00515 2.6e-24 E lactoylglutathione lyase activity
APOBLMKD_00516 9.1e-36 yozE S Belongs to the UPF0346 family
APOBLMKD_00517 9.2e-46 yokU S YokU-like protein, putative antitoxin
APOBLMKD_00518 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
APOBLMKD_00519 8.6e-159 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
APOBLMKD_00520 8.1e-254 yodQ 3.5.1.16 E Acetylornithine deacetylase
APOBLMKD_00521 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APOBLMKD_00522 2.2e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APOBLMKD_00523 8.3e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOBLMKD_00524 1.4e-64 yosT L Bacterial transcription activator, effector binding domain
APOBLMKD_00526 1.4e-144 yiiD K acetyltransferase
APOBLMKD_00527 1.3e-240 cgeD M maturation of the outermost layer of the spore
APOBLMKD_00528 1.2e-40 cgeC
APOBLMKD_00529 1.6e-52 cgeA
APOBLMKD_00530 1.2e-164 cgeB S Spore maturation protein
APOBLMKD_00531 3.7e-218 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
APOBLMKD_00532 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
APOBLMKD_00538 1.7e-77
APOBLMKD_00539 2.5e-22 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
APOBLMKD_00540 2.6e-08
APOBLMKD_00543 5.3e-75 yoqH M LysM domain
APOBLMKD_00544 1.9e-206 S aspartate phosphatase
APOBLMKD_00547 7.2e-157 3.4.24.40 S amine dehydrogenase activity
APOBLMKD_00549 2.6e-08 S Domain of unknown function (DUF4879)
APOBLMKD_00550 7e-24
APOBLMKD_00551 6.6e-30 S Acetyltransferase (GNAT) domain
APOBLMKD_00552 4.9e-89 yokK S SMI1 / KNR4 family
APOBLMKD_00553 7.5e-53 S SMI1-KNR4 cell-wall
APOBLMKD_00554 4.1e-288 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APOBLMKD_00555 2.4e-26 yokH G SMI1 / KNR4 family
APOBLMKD_00556 1.7e-47 yokH G SMI1 / KNR4 family
APOBLMKD_00558 2.7e-302 yokA L Recombinase
APOBLMKD_00559 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
APOBLMKD_00560 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
APOBLMKD_00561 2.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APOBLMKD_00562 1.4e-66 ypoP K transcriptional
APOBLMKD_00563 6.1e-97 ypmS S protein conserved in bacteria
APOBLMKD_00564 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
APOBLMKD_00565 3.7e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
APOBLMKD_00566 4.1e-37 ypmP S Protein of unknown function (DUF2535)
APOBLMKD_00567 1.1e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
APOBLMKD_00568 8.3e-174 pspF K Transcriptional regulator
APOBLMKD_00569 1.6e-109 hlyIII S protein, Hemolysin III
APOBLMKD_00570 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APOBLMKD_00571 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APOBLMKD_00572 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APOBLMKD_00573 8.5e-113 ypjP S YpjP-like protein
APOBLMKD_00574 1.1e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
APOBLMKD_00575 1e-75 yphP S Belongs to the UPF0403 family
APOBLMKD_00576 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
APOBLMKD_00577 2.2e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
APOBLMKD_00578 3.1e-99 ypgQ S phosphohydrolase
APOBLMKD_00579 7.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
APOBLMKD_00580 2.5e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
APOBLMKD_00581 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
APOBLMKD_00582 1e-30 cspD K Cold-shock protein
APOBLMKD_00583 1.3e-11 degR
APOBLMKD_00584 6.1e-36 S Protein of unknown function (DUF2564)
APOBLMKD_00585 1.5e-28 ypeQ S Zinc-finger
APOBLMKD_00586 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
APOBLMKD_00587 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
APOBLMKD_00588 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
APOBLMKD_00590 1.7e-162 polA 2.7.7.7 L 5'3' exonuclease
APOBLMKD_00592 2.2e-38 ypbS S Protein of unknown function (DUF2533)
APOBLMKD_00593 0.0 ypbR S Dynamin family
APOBLMKD_00594 1.1e-89 ypbQ S protein conserved in bacteria
APOBLMKD_00595 6.1e-202 bcsA Q Naringenin-chalcone synthase
APOBLMKD_00596 1.3e-105 J Acetyltransferase (GNAT) domain
APOBLMKD_00597 6e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
APOBLMKD_00599 6.2e-20 ydfR S Protein of unknown function (DUF421)
APOBLMKD_00600 3.2e-57 ydfR S Protein of unknown function (DUF421)
APOBLMKD_00601 1.9e-98 yrdC 3.5.1.19 Q Isochorismatase family
APOBLMKD_00603 6.5e-235 pbuX F xanthine
APOBLMKD_00604 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APOBLMKD_00605 4.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
APOBLMKD_00606 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
APOBLMKD_00608 6.6e-22 S YpzG-like protein
APOBLMKD_00609 2.7e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
APOBLMKD_00610 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APOBLMKD_00611 1.1e-98 ypsA S Belongs to the UPF0398 family
APOBLMKD_00612 9.9e-33 cotD S Inner spore coat protein D
APOBLMKD_00614 1.6e-219 yprB L RNase_H superfamily
APOBLMKD_00615 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
APOBLMKD_00616 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
APOBLMKD_00617 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
APOBLMKD_00618 2.1e-49 yppG S YppG-like protein
APOBLMKD_00620 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
APOBLMKD_00623 5.7e-188 yppC S Protein of unknown function (DUF2515)
APOBLMKD_00624 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APOBLMKD_00625 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APOBLMKD_00626 2.5e-91 ypoC
APOBLMKD_00627 2.7e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APOBLMKD_00628 3e-130 dnaD L DNA replication protein DnaD
APOBLMKD_00629 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
APOBLMKD_00630 6.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
APOBLMKD_00631 1.5e-80 ypmB S protein conserved in bacteria
APOBLMKD_00632 6.7e-23 ypmA S Protein of unknown function (DUF4264)
APOBLMKD_00633 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
APOBLMKD_00634 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
APOBLMKD_00635 1.5e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
APOBLMKD_00636 6.6e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
APOBLMKD_00637 2.4e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APOBLMKD_00638 2.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APOBLMKD_00639 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
APOBLMKD_00640 1.3e-131 bshB1 S proteins, LmbE homologs
APOBLMKD_00641 1.2e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
APOBLMKD_00642 2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APOBLMKD_00643 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
APOBLMKD_00644 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
APOBLMKD_00645 2.9e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
APOBLMKD_00646 3.6e-140 ypjB S sporulation protein
APOBLMKD_00647 3.2e-104 ypjA S membrane
APOBLMKD_00648 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
APOBLMKD_00649 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
APOBLMKD_00650 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
APOBLMKD_00651 3.2e-77 ypiF S Protein of unknown function (DUF2487)
APOBLMKD_00652 2.1e-99 ypiB S Belongs to the UPF0302 family
APOBLMKD_00653 9.1e-234 S COG0457 FOG TPR repeat
APOBLMKD_00654 2.3e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APOBLMKD_00655 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
APOBLMKD_00656 6.4e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APOBLMKD_00657 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
APOBLMKD_00658 1.6e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APOBLMKD_00659 7.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
APOBLMKD_00660 5.6e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
APOBLMKD_00661 8.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APOBLMKD_00662 2.5e-286 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APOBLMKD_00663 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
APOBLMKD_00664 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
APOBLMKD_00665 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APOBLMKD_00666 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
APOBLMKD_00667 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
APOBLMKD_00668 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APOBLMKD_00669 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APOBLMKD_00670 1.4e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
APOBLMKD_00671 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
APOBLMKD_00672 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
APOBLMKD_00673 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APOBLMKD_00674 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
APOBLMKD_00675 1.1e-133 yphF
APOBLMKD_00676 3.3e-16 yphE S Protein of unknown function (DUF2768)
APOBLMKD_00677 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
APOBLMKD_00678 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
APOBLMKD_00679 7.2e-104 yphA
APOBLMKD_00680 4.7e-08 S YpzI-like protein
APOBLMKD_00681 6.5e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APOBLMKD_00682 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
APOBLMKD_00683 1e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
APOBLMKD_00684 1.4e-12 S Family of unknown function (DUF5359)
APOBLMKD_00685 1.4e-60 ypfA M Flagellar protein YcgR
APOBLMKD_00686 4.6e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
APOBLMKD_00687 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
APOBLMKD_00688 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
APOBLMKD_00689 8.5e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
APOBLMKD_00690 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
APOBLMKD_00691 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APOBLMKD_00692 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
APOBLMKD_00693 5.7e-85 ypbF S Protein of unknown function (DUF2663)
APOBLMKD_00694 1.2e-79 ypbE M Lysin motif
APOBLMKD_00695 5.2e-99 ypbD S metal-dependent membrane protease
APOBLMKD_00696 3e-270 recQ 3.6.4.12 L DNA helicase
APOBLMKD_00697 1.1e-192 ypbB 5.1.3.1 S protein conserved in bacteria
APOBLMKD_00698 3.6e-41 fer C Ferredoxin
APOBLMKD_00699 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APOBLMKD_00700 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOBLMKD_00701 6.3e-191 rsiX
APOBLMKD_00702 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
APOBLMKD_00703 0.0 resE 2.7.13.3 T Histidine kinase
APOBLMKD_00704 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_00705 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
APOBLMKD_00706 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
APOBLMKD_00707 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
APOBLMKD_00708 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APOBLMKD_00709 1.3e-88 spmB S Spore maturation protein
APOBLMKD_00710 2.3e-102 spmA S Spore maturation protein
APOBLMKD_00711 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
APOBLMKD_00712 3.8e-93 ypuI S Protein of unknown function (DUF3907)
APOBLMKD_00713 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APOBLMKD_00714 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APOBLMKD_00716 2.9e-93 ypuF S Domain of unknown function (DUF309)
APOBLMKD_00717 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOBLMKD_00718 1.2e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APOBLMKD_00719 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APOBLMKD_00720 1.1e-110 ribE 2.5.1.9 H Riboflavin synthase
APOBLMKD_00721 3.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APOBLMKD_00722 6.4e-49 ypuD
APOBLMKD_00723 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
APOBLMKD_00724 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
APOBLMKD_00725 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APOBLMKD_00726 1.9e-153 ypuA S Secreted protein
APOBLMKD_00727 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APOBLMKD_00728 9.2e-270 spoVAF EG Stage V sporulation protein AF
APOBLMKD_00729 9.7e-109 spoVAEA S stage V sporulation protein
APOBLMKD_00730 5e-57 spoVAEB S stage V sporulation protein
APOBLMKD_00731 1.2e-188 spoVAD I Stage V sporulation protein AD
APOBLMKD_00732 6e-79 spoVAC S stage V sporulation protein AC
APOBLMKD_00733 5.1e-60 spoVAB S Stage V sporulation protein AB
APOBLMKD_00734 4.8e-111 spoVAA S Stage V sporulation protein AA
APOBLMKD_00735 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOBLMKD_00736 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
APOBLMKD_00737 6.6e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
APOBLMKD_00738 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
APOBLMKD_00739 2.7e-146 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
APOBLMKD_00740 9.7e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
APOBLMKD_00741 2.8e-165 xerD L recombinase XerD
APOBLMKD_00742 3.7e-37 S Protein of unknown function (DUF4227)
APOBLMKD_00743 1.9e-80 fur P Belongs to the Fur family
APOBLMKD_00744 7.2e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
APOBLMKD_00746 8.6e-34 yqkK
APOBLMKD_00747 5.7e-22
APOBLMKD_00748 3.8e-243 mleA 1.1.1.38 C malic enzyme
APOBLMKD_00749 1.6e-239 mleN C Na H antiporter
APOBLMKD_00750 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
APOBLMKD_00751 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
APOBLMKD_00752 1e-57 ansR K Transcriptional regulator
APOBLMKD_00753 7.6e-219 yqxK 3.6.4.12 L DNA helicase
APOBLMKD_00754 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
APOBLMKD_00756 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
APOBLMKD_00758 9e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
APOBLMKD_00759 3.2e-39 yqkC S Protein of unknown function (DUF2552)
APOBLMKD_00760 7.7e-61 yqkB S Belongs to the HesB IscA family
APOBLMKD_00761 1.2e-172 yqkA K GrpB protein
APOBLMKD_00762 2.8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
APOBLMKD_00763 8.7e-89 yqjY K acetyltransferase
APOBLMKD_00764 1.4e-234 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APOBLMKD_00765 2.1e-55 S YolD-like protein
APOBLMKD_00767 1.3e-185 yueF S transporter activity
APOBLMKD_00769 2.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOBLMKD_00770 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
APOBLMKD_00771 3.7e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
APOBLMKD_00772 1.2e-140 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
APOBLMKD_00773 1.2e-172 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
APOBLMKD_00774 6.9e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APOBLMKD_00775 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
APOBLMKD_00776 1.7e-238 pksG 2.3.3.10 I synthase
APOBLMKD_00777 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
APOBLMKD_00778 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
APOBLMKD_00779 0.0 Q Polyketide synthase of type I
APOBLMKD_00780 0.0 pfaA Q Polyketide synthase of type I
APOBLMKD_00781 0.0 pksJ Q Polyketide synthase of type I
APOBLMKD_00782 7.5e-77 ctsR K Belongs to the CtsR family
APOBLMKD_00783 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
APOBLMKD_00784 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
APOBLMKD_00785 0.0 clpC O Belongs to the ClpA ClpB family
APOBLMKD_00786 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APOBLMKD_00787 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
APOBLMKD_00788 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
APOBLMKD_00789 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
APOBLMKD_00790 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
APOBLMKD_00791 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APOBLMKD_00792 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
APOBLMKD_00793 5.3e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
APOBLMKD_00794 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APOBLMKD_00795 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APOBLMKD_00796 4.2e-89 yacP S RNA-binding protein containing a PIN domain
APOBLMKD_00797 8.9e-116 sigH K Belongs to the sigma-70 factor family
APOBLMKD_00798 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APOBLMKD_00799 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
APOBLMKD_00800 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APOBLMKD_00801 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APOBLMKD_00802 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APOBLMKD_00803 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APOBLMKD_00804 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
APOBLMKD_00805 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOBLMKD_00806 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOBLMKD_00807 2.1e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
APOBLMKD_00808 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APOBLMKD_00809 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APOBLMKD_00810 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APOBLMKD_00811 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APOBLMKD_00812 8e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
APOBLMKD_00813 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
APOBLMKD_00814 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APOBLMKD_00815 3e-105 rplD J Forms part of the polypeptide exit tunnel
APOBLMKD_00816 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APOBLMKD_00817 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APOBLMKD_00818 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APOBLMKD_00819 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APOBLMKD_00820 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APOBLMKD_00821 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APOBLMKD_00822 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
APOBLMKD_00823 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APOBLMKD_00824 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APOBLMKD_00825 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APOBLMKD_00826 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APOBLMKD_00827 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APOBLMKD_00828 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APOBLMKD_00829 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APOBLMKD_00830 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APOBLMKD_00831 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APOBLMKD_00832 1.9e-23 rpmD J Ribosomal protein L30
APOBLMKD_00833 4.1e-72 rplO J binds to the 23S rRNA
APOBLMKD_00834 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APOBLMKD_00835 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APOBLMKD_00836 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
APOBLMKD_00837 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APOBLMKD_00838 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
APOBLMKD_00839 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APOBLMKD_00840 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APOBLMKD_00841 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOBLMKD_00842 4.7e-58 rplQ J Ribosomal protein L17
APOBLMKD_00843 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOBLMKD_00844 3.1e-148 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOBLMKD_00845 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOBLMKD_00846 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APOBLMKD_00847 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APOBLMKD_00848 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
APOBLMKD_00849 6.9e-144 ybaJ Q Methyltransferase domain
APOBLMKD_00850 1.2e-82 yizA S Damage-inducible protein DinB
APOBLMKD_00851 4.2e-77 ybaK S Protein of unknown function (DUF2521)
APOBLMKD_00852 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOBLMKD_00853 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
APOBLMKD_00854 1.7e-75 gerD
APOBLMKD_00855 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
APOBLMKD_00856 2.1e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
APOBLMKD_00857 5.2e-69 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_00858 1.1e-52 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_00859 1.1e-253 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_00860 1.4e-26 Q PFAM Collagen triple helix
APOBLMKD_00861 1e-233 yflS P Sodium:sulfate symporter transmembrane region
APOBLMKD_00862 1.2e-241 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
APOBLMKD_00863 1.3e-57 yflT S Heat induced stress protein YflT
APOBLMKD_00864 1.2e-24 S Protein of unknown function (DUF3212)
APOBLMKD_00865 2e-186 yfmJ S N-terminal domain of oxidoreductase
APOBLMKD_00866 3.7e-65 yfmK 2.3.1.128 K acetyltransferase
APOBLMKD_00867 6.7e-204 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
APOBLMKD_00868 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APOBLMKD_00869 2.6e-206 yfmO EGP Major facilitator Superfamily
APOBLMKD_00870 1.8e-69 yfmP K transcriptional
APOBLMKD_00871 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APOBLMKD_00872 1.2e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APOBLMKD_00873 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
APOBLMKD_00874 7.5e-107 yfmS NT chemotaxis protein
APOBLMKD_00875 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APOBLMKD_00876 3e-246 yfnA E amino acid
APOBLMKD_00877 6.8e-218 fsr P COG0477 Permeases of the major facilitator superfamily
APOBLMKD_00878 4.9e-184 yfnD M Nucleotide-diphospho-sugar transferase
APOBLMKD_00879 2.8e-221 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
APOBLMKD_00880 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
APOBLMKD_00881 7.1e-172 yfnG 4.2.1.45 M dehydratase
APOBLMKD_00882 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
APOBLMKD_00883 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APOBLMKD_00884 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
APOBLMKD_00885 7.5e-197 yetN S Protein of unknown function (DUF3900)
APOBLMKD_00886 1.7e-204 yetM CH FAD binding domain
APOBLMKD_00887 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_00889 1.1e-105 yetJ S Belongs to the BI1 family
APOBLMKD_00890 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
APOBLMKD_00891 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
APOBLMKD_00892 5.9e-133 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
APOBLMKD_00893 1.6e-104 cysW P COG4208 ABC-type sulfate transport system, permease component
APOBLMKD_00894 5.8e-112 cysT O COG0555 ABC-type sulfate transport system, permease component
APOBLMKD_00895 1.7e-137 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
APOBLMKD_00896 6.4e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APOBLMKD_00897 5.8e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOBLMKD_00898 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
APOBLMKD_00899 7.4e-121 yetF S membrane
APOBLMKD_00901 5.4e-95 yesJ K Acetyltransferase (GNAT) family
APOBLMKD_00902 8.9e-104 cotJC P Spore Coat
APOBLMKD_00903 1.3e-44 cotJB S CotJB protein
APOBLMKD_00904 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
APOBLMKD_00905 1.2e-107 aadK G Streptomycin adenylyltransferase
APOBLMKD_00907 9.4e-127 yeeN K transcriptional regulatory protein
APOBLMKD_00908 3.8e-30 csfB S Inhibitor of sigma-G Gin
APOBLMKD_00909 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
APOBLMKD_00910 4.3e-187 yaaN P Belongs to the TelA family
APOBLMKD_00911 6.4e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
APOBLMKD_00912 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APOBLMKD_00913 7.5e-55 yaaQ S protein conserved in bacteria
APOBLMKD_00914 1.2e-71 yaaR S protein conserved in bacteria
APOBLMKD_00915 1.3e-182 holB 2.7.7.7 L DNA polymerase III
APOBLMKD_00916 8.8e-145 yaaT S stage 0 sporulation protein
APOBLMKD_00917 7.7e-37 yabA L Involved in initiation control of chromosome replication
APOBLMKD_00918 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
APOBLMKD_00919 5.2e-47 yazA L endonuclease containing a URI domain
APOBLMKD_00920 1.4e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APOBLMKD_00921 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
APOBLMKD_00922 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APOBLMKD_00923 4.5e-143 tatD L hydrolase, TatD
APOBLMKD_00924 2.7e-231 rpfB GH23 T protein conserved in bacteria
APOBLMKD_00925 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APOBLMKD_00926 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APOBLMKD_00927 8.4e-146 yabG S peptidase
APOBLMKD_00928 7.8e-39 veg S protein conserved in bacteria
APOBLMKD_00929 2.9e-27 sspF S DNA topological change
APOBLMKD_00930 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APOBLMKD_00931 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
APOBLMKD_00932 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
APOBLMKD_00933 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
APOBLMKD_00934 2e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APOBLMKD_00935 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APOBLMKD_00936 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
APOBLMKD_00937 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APOBLMKD_00938 3.7e-40 yabK S Peptide ABC transporter permease
APOBLMKD_00939 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APOBLMKD_00940 6.2e-91 spoVT K stage V sporulation protein
APOBLMKD_00941 2.5e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOBLMKD_00942 4e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
APOBLMKD_00943 8.1e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
APOBLMKD_00944 1.9e-49 yabP S Sporulation protein YabP
APOBLMKD_00945 2.9e-103 yabQ S spore cortex biosynthesis protein
APOBLMKD_00946 4.1e-57 divIC D Septum formation initiator
APOBLMKD_00947 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
APOBLMKD_00950 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
APOBLMKD_00951 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
APOBLMKD_00952 1.4e-184 KLT serine threonine protein kinase
APOBLMKD_00953 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APOBLMKD_00954 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APOBLMKD_00955 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APOBLMKD_00956 7.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
APOBLMKD_00957 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APOBLMKD_00958 1.1e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
APOBLMKD_00959 8.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APOBLMKD_00960 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APOBLMKD_00961 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
APOBLMKD_00962 3.6e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
APOBLMKD_00963 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
APOBLMKD_00964 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APOBLMKD_00965 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APOBLMKD_00966 4.5e-29 yazB K transcriptional
APOBLMKD_00967 7.8e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APOBLMKD_00968 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
APOBLMKD_00969 1.3e-251 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_00970 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
APOBLMKD_00971 1.5e-140 srfAD Q thioesterase
APOBLMKD_00972 7.9e-249 bamJ E Aminotransferase class I and II
APOBLMKD_00973 3.2e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
APOBLMKD_00974 4.5e-109 yczE S membrane
APOBLMKD_00975 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APOBLMKD_00976 6.3e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
APOBLMKD_00977 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
APOBLMKD_00978 4.7e-157 bsdA K LysR substrate binding domain
APOBLMKD_00979 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
APOBLMKD_00980 9.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
APOBLMKD_00981 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
APOBLMKD_00982 1.3e-76 yclD
APOBLMKD_00983 1.2e-269 dtpT E amino acid peptide transporter
APOBLMKD_00984 3.2e-277 yclG M Pectate lyase superfamily protein
APOBLMKD_00986 7.8e-294 gerKA EG Spore germination protein
APOBLMKD_00987 1.3e-232 gerKC S spore germination
APOBLMKD_00988 3.3e-195 gerKB F Spore germination protein
APOBLMKD_00989 1.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOBLMKD_00990 1.1e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOBLMKD_00991 5.6e-141 yxeM M Belongs to the bacterial solute-binding protein 3 family
APOBLMKD_00992 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
APOBLMKD_00993 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
APOBLMKD_00994 2.4e-217 yxeP 3.5.1.47 E hydrolase activity
APOBLMKD_00995 1.4e-253 yxeQ S MmgE/PrpD family
APOBLMKD_00996 8.1e-120 yclH P ABC transporter
APOBLMKD_00997 1.5e-229 yclI V ABC transporter (permease) YclI
APOBLMKD_00998 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_00999 2.4e-259 T PhoQ Sensor
APOBLMKD_01000 9.5e-81 S aspartate phosphatase
APOBLMKD_01002 1.6e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
APOBLMKD_01003 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_01004 4.4e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_01005 6.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
APOBLMKD_01006 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
APOBLMKD_01007 2.1e-247 ycnB EGP Major facilitator Superfamily
APOBLMKD_01008 3e-151 ycnC K Transcriptional regulator
APOBLMKD_01009 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
APOBLMKD_01010 1e-44 ycnE S Monooxygenase
APOBLMKD_01011 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
APOBLMKD_01012 1.8e-259 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOBLMKD_01013 1.9e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOBLMKD_01014 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APOBLMKD_01015 4.7e-149 glcU U Glucose uptake
APOBLMKD_01016 1.9e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_01017 1.3e-97 ycnI S protein conserved in bacteria
APOBLMKD_01018 5.2e-298 ycnJ P protein, homolog of Cu resistance protein CopC
APOBLMKD_01019 5.6e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
APOBLMKD_01020 1.6e-55
APOBLMKD_01021 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
APOBLMKD_01022 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
APOBLMKD_01023 1.7e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
APOBLMKD_01024 7.9e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
APOBLMKD_01026 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
APOBLMKD_01027 4.3e-138 ycsF S Belongs to the UPF0271 (lamB) family
APOBLMKD_01028 9.7e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
APOBLMKD_01029 5.7e-149 ycsI S Belongs to the D-glutamate cyclase family
APOBLMKD_01030 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
APOBLMKD_01031 3.2e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
APOBLMKD_01032 9.8e-130 kipR K Transcriptional regulator
APOBLMKD_01033 2.7e-117 ycsK E anatomical structure formation involved in morphogenesis
APOBLMKD_01035 5.1e-56 yczJ S biosynthesis
APOBLMKD_01036 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
APOBLMKD_01037 8.3e-173 ydhF S Oxidoreductase
APOBLMKD_01038 0.0 mtlR K transcriptional regulator, MtlR
APOBLMKD_01039 3.2e-286 ydaB IQ acyl-CoA ligase
APOBLMKD_01040 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_01041 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
APOBLMKD_01042 3.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APOBLMKD_01043 1.4e-77 ydaG 1.4.3.5 S general stress protein
APOBLMKD_01044 2.1e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
APOBLMKD_01045 1.3e-47 ydzA EGP Major facilitator Superfamily
APOBLMKD_01046 4.3e-74 lrpC K Transcriptional regulator
APOBLMKD_01047 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APOBLMKD_01048 1.1e-195 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
APOBLMKD_01049 2.1e-146 ydaK T Diguanylate cyclase, GGDEF domain
APOBLMKD_01050 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
APOBLMKD_01051 2.5e-231 ydaM M Glycosyl transferase family group 2
APOBLMKD_01052 0.0 ydaN S Bacterial cellulose synthase subunit
APOBLMKD_01053 0.0 ydaO E amino acid
APOBLMKD_01054 3.1e-72 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
APOBLMKD_01055 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
APOBLMKD_01056 3.4e-63 K acetyltransferase
APOBLMKD_01060 2.2e-40
APOBLMKD_01061 3e-36
APOBLMKD_01062 2.2e-08 2.1.1.72 KL DNA methylase
APOBLMKD_01063 7.8e-20 K DNA binding
APOBLMKD_01064 1.3e-37 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
APOBLMKD_01065 1.3e-58 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
APOBLMKD_01066 3.6e-79 S Domain of unknown function (DUF4145)
APOBLMKD_01067 7.2e-26
APOBLMKD_01068 4.5e-22
APOBLMKD_01069 4e-23 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOBLMKD_01070 1.2e-85 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
APOBLMKD_01071 2.8e-69
APOBLMKD_01072 6e-17 S Histidine kinase
APOBLMKD_01074 1.4e-12
APOBLMKD_01076 1e-72
APOBLMKD_01077 5.3e-98
APOBLMKD_01078 6.1e-39
APOBLMKD_01079 9.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
APOBLMKD_01081 2.5e-33 ydaT
APOBLMKD_01082 3.7e-72 yvaD S Family of unknown function (DUF5360)
APOBLMKD_01083 1.2e-53 yvaE P Small Multidrug Resistance protein
APOBLMKD_01084 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
APOBLMKD_01085 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APOBLMKD_01086 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APOBLMKD_01087 8.1e-38 yaaB S Domain of unknown function (DUF370)
APOBLMKD_01088 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APOBLMKD_01089 2.4e-33 yaaA S S4 domain
APOBLMKD_01090 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APOBLMKD_01091 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APOBLMKD_01092 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APOBLMKD_01093 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APOBLMKD_01094 1.3e-108 jag S single-stranded nucleic acid binding R3H
APOBLMKD_01095 5.8e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APOBLMKD_01096 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APOBLMKD_01097 1.6e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
APOBLMKD_01098 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
APOBLMKD_01099 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
APOBLMKD_01100 7.9e-149 spo0J K Belongs to the ParB family
APOBLMKD_01101 6.2e-111 yyaC S Sporulation protein YyaC
APOBLMKD_01102 5.3e-176 yyaD S Membrane
APOBLMKD_01103 2.3e-33 yyzM S protein conserved in bacteria
APOBLMKD_01104 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOBLMKD_01105 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APOBLMKD_01106 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
APOBLMKD_01107 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APOBLMKD_01108 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APOBLMKD_01109 5.3e-104 adaA 3.2.2.21 K Transcriptional regulator
APOBLMKD_01110 9.3e-98 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APOBLMKD_01111 2.7e-140 xth 3.1.11.2 L exodeoxyribonuclease III
APOBLMKD_01112 1.5e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
APOBLMKD_01113 2.9e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOBLMKD_01114 2e-247 ydjK G Sugar (and other) transporter
APOBLMKD_01115 1.2e-160 yyaK S CAAX protease self-immunity
APOBLMKD_01116 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
APOBLMKD_01117 9.2e-22 yyaL O Highly conserved protein containing a thioredoxin domain
APOBLMKD_01119 1.2e-10 U Preprotein translocase subunit SecB
APOBLMKD_01121 1.9e-27 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
APOBLMKD_01122 2.7e-40 qacC U Small Multidrug Resistance protein
APOBLMKD_01123 7.6e-14 yvaO K Transcriptional
APOBLMKD_01124 2.8e-77 K Transcriptional regulator
APOBLMKD_01125 1.1e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APOBLMKD_01126 1.6e-131 ydfC EG EamA-like transporter family
APOBLMKD_01127 2.5e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOBLMKD_01128 6.6e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
APOBLMKD_01129 8.6e-162 K Transcriptional regulator
APOBLMKD_01130 2.3e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
APOBLMKD_01131 2.4e-161 eaeH M Domain of Unknown Function (DUF1259)
APOBLMKD_01133 1.6e-76 yybA 2.3.1.57 K transcriptional
APOBLMKD_01134 1.5e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
APOBLMKD_01135 4.1e-69 ydgJ K Winged helix DNA-binding domain
APOBLMKD_01136 5.6e-115 drgA C nitroreductase
APOBLMKD_01137 2.2e-55 ypaA S Protein of unknown function (DUF1304)
APOBLMKD_01138 3.2e-159 G Major Facilitator Superfamily
APOBLMKD_01139 6.3e-77 dinB S PFAM DinB family protein
APOBLMKD_01140 2.2e-114 K FCD domain
APOBLMKD_01141 2.1e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
APOBLMKD_01142 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
APOBLMKD_01143 1.2e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APOBLMKD_01144 3.9e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
APOBLMKD_01145 8.2e-66 ydeP3 K Transcriptional regulator
APOBLMKD_01146 2.1e-83 cotF M Spore coat protein
APOBLMKD_01148 2.4e-159 yybS S membrane
APOBLMKD_01149 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
APOBLMKD_01150 4.9e-73 rplI J binds to the 23S rRNA
APOBLMKD_01151 6.4e-122 KLT COG0515 Serine threonine protein kinase
APOBLMKD_01152 1.1e-121 S GlcNAc-PI de-N-acetylase
APOBLMKD_01153 5.1e-243 M Glycosyltransferase Family 4
APOBLMKD_01154 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
APOBLMKD_01155 2.6e-202 S Ecdysteroid kinase
APOBLMKD_01156 6.4e-235 M Glycosyltransferase Family 4
APOBLMKD_01157 4.6e-17 yycC K YycC-like protein
APOBLMKD_01159 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
APOBLMKD_01160 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
APOBLMKD_01161 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOBLMKD_01162 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APOBLMKD_01167 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_01168 0.0 vicK 2.7.13.3 T Histidine kinase
APOBLMKD_01169 2.5e-261 yycH S protein conserved in bacteria
APOBLMKD_01170 1.1e-150 yycI S protein conserved in bacteria
APOBLMKD_01171 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
APOBLMKD_01172 1.9e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APOBLMKD_01173 2.1e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_01174 2.3e-246 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
APOBLMKD_01175 2.7e-188 2.7.7.73, 2.7.7.80 H ThiF family
APOBLMKD_01176 3.4e-255
APOBLMKD_01177 4.5e-195 S Major Facilitator Superfamily
APOBLMKD_01178 1.3e-304 S ABC transporter
APOBLMKD_01179 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
APOBLMKD_01180 7.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
APOBLMKD_01181 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
APOBLMKD_01182 1.1e-256 rocE E amino acid
APOBLMKD_01183 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
APOBLMKD_01184 1.1e-198 S Histidine kinase
APOBLMKD_01186 1.4e-86 yycN 2.3.1.128 K Acetyltransferase
APOBLMKD_01187 1.5e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
APOBLMKD_01188 2.7e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
APOBLMKD_01189 4.6e-216 yycP
APOBLMKD_01191 7.9e-08 S YyzF-like protein
APOBLMKD_01192 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APOBLMKD_01193 7.9e-73 mobC K Transcriptional regulator
APOBLMKD_01194 5.8e-102
APOBLMKD_01195 7.9e-11
APOBLMKD_01196 3.9e-301 D Protein of unknown function (DUF3732)
APOBLMKD_01197 1.9e-30 M1-386
APOBLMKD_01198 1.8e-163 S Fusaric acid resistance protein-like
APOBLMKD_01199 1.3e-179 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
APOBLMKD_01200 7.4e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
APOBLMKD_01201 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
APOBLMKD_01202 2e-152 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
APOBLMKD_01203 5.4e-83 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
APOBLMKD_01204 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
APOBLMKD_01205 5.5e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
APOBLMKD_01206 1.1e-286 ahpF O Alkyl hydroperoxide reductase
APOBLMKD_01207 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
APOBLMKD_01208 3e-122 E Ring-cleavage extradiol dioxygenase
APOBLMKD_01209 8.4e-73 yxaI S membrane protein domain
APOBLMKD_01210 2.9e-202 EGP Major facilitator Superfamily
APOBLMKD_01211 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
APOBLMKD_01212 1.7e-64 S Family of unknown function (DUF5391)
APOBLMKD_01213 2.8e-142 S PQQ-like domain
APOBLMKD_01214 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
APOBLMKD_01215 9.6e-214 yxbF K Bacterial regulatory proteins, tetR family
APOBLMKD_01216 2.5e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
APOBLMKD_01217 4.5e-200 desK 2.7.13.3 T Histidine kinase
APOBLMKD_01218 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOBLMKD_01219 6.9e-150 IQ Enoyl-(Acyl carrier protein) reductase
APOBLMKD_01220 0.0 htpG O Molecular chaperone. Has ATPase activity
APOBLMKD_01221 4.3e-245 csbC EGP Major facilitator Superfamily
APOBLMKD_01222 4.6e-174 iolS C Aldo keto reductase
APOBLMKD_01223 2e-135 iolR K COG1349 Transcriptional regulators of sugar metabolism
APOBLMKD_01224 4.8e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APOBLMKD_01225 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
APOBLMKD_01226 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
APOBLMKD_01227 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
APOBLMKD_01228 3.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
APOBLMKD_01229 6.7e-232 iolF EGP Major facilitator Superfamily
APOBLMKD_01230 5.8e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
APOBLMKD_01231 3.3e-166 iolH G Xylose isomerase-like TIM barrel
APOBLMKD_01232 2.5e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
APOBLMKD_01233 3.3e-158 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
APOBLMKD_01234 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_01235 2.5e-175 T PhoQ Sensor
APOBLMKD_01236 3.6e-140 yxdL V ABC transporter, ATP-binding protein
APOBLMKD_01237 0.0 yxdM V ABC transporter (permease)
APOBLMKD_01238 1.3e-57 yxeA S Protein of unknown function (DUF1093)
APOBLMKD_01239 4.1e-178 fhuD P Periplasmic binding protein
APOBLMKD_01240 1.3e-34
APOBLMKD_01241 8.4e-23 yxeD
APOBLMKD_01245 2.6e-149 yidA S hydrolases of the HAD superfamily
APOBLMKD_01246 2.1e-171 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APOBLMKD_01247 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APOBLMKD_01248 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APOBLMKD_01249 1.5e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
APOBLMKD_01250 4.4e-253 lysP E amino acid
APOBLMKD_01251 9.4e-175 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
APOBLMKD_01252 2.2e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
APOBLMKD_01253 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
APOBLMKD_01254 3.6e-285 hutH 4.3.1.3 E Histidine ammonia-lyase
APOBLMKD_01255 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
APOBLMKD_01256 2e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
APOBLMKD_01257 3.1e-60 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
APOBLMKD_01258 0.0 L HKD family nuclease
APOBLMKD_01259 1.8e-72 yxiE T Belongs to the universal stress protein A family
APOBLMKD_01260 2.7e-147 yxxF EG EamA-like transporter family
APOBLMKD_01261 2.6e-197 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
APOBLMKD_01262 0.0 wapA M COG3209 Rhs family protein
APOBLMKD_01263 9.3e-88
APOBLMKD_01267 3.2e-110
APOBLMKD_01268 3.7e-13 S YxiJ-like protein
APOBLMKD_01269 8.7e-20
APOBLMKD_01270 1.6e-48 yxiI S Protein of unknown function (DUF2716)
APOBLMKD_01271 1.2e-61 S SMI1-KNR4 cell-wall
APOBLMKD_01274 2e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
APOBLMKD_01275 4.3e-220 yxiO S COG2270 Permeases of the major facilitator superfamily
APOBLMKD_01276 2.7e-20 licT K transcriptional antiterminator
APOBLMKD_01277 2.3e-70 licT K transcriptional antiterminator
APOBLMKD_01279 2e-140 exoK GH16 M licheninase activity
APOBLMKD_01280 1.4e-221 citH C Citrate transporter
APOBLMKD_01281 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
APOBLMKD_01282 1.5e-49 yxiS
APOBLMKD_01283 3.6e-72 T Domain of unknown function (DUF4163)
APOBLMKD_01284 3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APOBLMKD_01285 6.5e-154 rlmA 2.1.1.187 Q Methyltransferase domain
APOBLMKD_01286 1.2e-216 yxjG 2.1.1.14 E Methionine synthase
APOBLMKD_01287 9.1e-86 yxjI S LURP-one-related
APOBLMKD_01290 9.8e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
APOBLMKD_01291 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
APOBLMKD_01292 3.8e-87 yxkC S Domain of unknown function (DUF4352)
APOBLMKD_01293 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APOBLMKD_01294 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
APOBLMKD_01295 1.3e-204 msmK P Belongs to the ABC transporter superfamily
APOBLMKD_01296 1.6e-154 yxkH G Polysaccharide deacetylase
APOBLMKD_01297 1e-214 cimH C COG3493 Na citrate symporter
APOBLMKD_01298 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
APOBLMKD_01299 2.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
APOBLMKD_01300 0.0 cydD V ATP-binding
APOBLMKD_01301 2.2e-291 cydD V ATP-binding protein
APOBLMKD_01302 1.5e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APOBLMKD_01303 1e-251 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
APOBLMKD_01304 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
APOBLMKD_01305 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
APOBLMKD_01306 2.1e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
APOBLMKD_01307 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
APOBLMKD_01308 1.4e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
APOBLMKD_01309 3.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APOBLMKD_01310 1.1e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APOBLMKD_01311 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
APOBLMKD_01312 5.8e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
APOBLMKD_01313 1.2e-225 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APOBLMKD_01314 1.5e-56 arsR K transcriptional
APOBLMKD_01315 1.3e-165 cbrA3 P Periplasmic binding protein
APOBLMKD_01316 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_01317 6.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_01318 3.5e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
APOBLMKD_01319 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
APOBLMKD_01320 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
APOBLMKD_01321 7.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APOBLMKD_01322 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
APOBLMKD_01323 2.3e-251 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APOBLMKD_01324 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
APOBLMKD_01325 3.1e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APOBLMKD_01326 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_01327 1.4e-228 dltB M membrane protein involved in D-alanine export
APOBLMKD_01328 8.7e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_01329 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
APOBLMKD_01330 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
APOBLMKD_01331 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
APOBLMKD_01332 1.9e-196 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APOBLMKD_01333 7.1e-49 ywaE K Transcriptional regulator
APOBLMKD_01334 4.1e-161 gspA M General stress
APOBLMKD_01335 6.4e-262 epr 3.4.21.62 O Belongs to the peptidase S8 family
APOBLMKD_01336 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APOBLMKD_01337 7.6e-67 ywbC 4.4.1.5 E glyoxalase
APOBLMKD_01338 3e-223 ywbD 2.1.1.191 J Methyltransferase
APOBLMKD_01339 2.6e-135 mta K transcriptional
APOBLMKD_01340 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
APOBLMKD_01341 1.3e-109 ywbG M effector of murein hydrolase
APOBLMKD_01342 4.2e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
APOBLMKD_01343 8.2e-152 ywbI K Transcriptional regulator
APOBLMKD_01344 1.3e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APOBLMKD_01345 7.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APOBLMKD_01346 1.1e-242 ywbN P Dyp-type peroxidase family protein
APOBLMKD_01347 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
APOBLMKD_01348 1.2e-131 S Streptomycin biosynthesis protein StrF
APOBLMKD_01349 1.1e-127 H Methionine biosynthesis protein MetW
APOBLMKD_01351 3.1e-110 ywcC K Bacterial regulatory proteins, tetR family
APOBLMKD_01352 5.1e-61 gtcA S GtrA-like protein
APOBLMKD_01353 3.6e-293 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
APOBLMKD_01354 8.4e-27 ywzA S membrane
APOBLMKD_01355 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
APOBLMKD_01356 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APOBLMKD_01357 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
APOBLMKD_01358 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
APOBLMKD_01359 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
APOBLMKD_01360 1.7e-76 ysnE K acetyltransferase
APOBLMKD_01361 6.2e-200 rodA D Belongs to the SEDS family
APOBLMKD_01362 2e-12
APOBLMKD_01363 1e-17
APOBLMKD_01364 4.8e-105 V MacB-like periplasmic core domain
APOBLMKD_01365 1.1e-62 yvrO V ATPases associated with a variety of cellular activities
APOBLMKD_01366 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
APOBLMKD_01367 8.9e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOBLMKD_01368 0.0 vpr O Belongs to the peptidase S8 family
APOBLMKD_01370 2.8e-151 sacT K transcriptional antiterminator
APOBLMKD_01371 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOBLMKD_01372 1.9e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
APOBLMKD_01373 7.4e-20 ywdA
APOBLMKD_01374 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APOBLMKD_01375 6.3e-57 pex K Transcriptional regulator PadR-like family
APOBLMKD_01376 1.5e-88 ywdD
APOBLMKD_01378 6.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
APOBLMKD_01379 1.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APOBLMKD_01380 4.7e-41 ywdI S Family of unknown function (DUF5327)
APOBLMKD_01381 5.4e-229 ywdJ F Xanthine uracil
APOBLMKD_01382 4.2e-46 ywdK S small membrane protein
APOBLMKD_01383 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
APOBLMKD_01384 1.7e-142 spsA M Spore Coat
APOBLMKD_01385 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
APOBLMKD_01386 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
APOBLMKD_01387 8.9e-156 spsD 2.3.1.210 K Spore Coat
APOBLMKD_01388 1.2e-213 spsE 2.5.1.56 M acid synthase
APOBLMKD_01389 2.6e-132 spsF M Spore Coat
APOBLMKD_01390 1.7e-179 spsG M Spore Coat
APOBLMKD_01391 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APOBLMKD_01392 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APOBLMKD_01393 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APOBLMKD_01394 3.5e-87 spsL 5.1.3.13 M Spore Coat
APOBLMKD_01395 1.9e-59
APOBLMKD_01396 9.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
APOBLMKD_01397 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
APOBLMKD_01398 0.0 rocB E arginine degradation protein
APOBLMKD_01399 1.2e-258 lysP E amino acid
APOBLMKD_01400 2.5e-204 tcaB EGP Major facilitator Superfamily
APOBLMKD_01401 3.5e-222 ywfA EGP Major facilitator Superfamily
APOBLMKD_01402 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
APOBLMKD_01403 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
APOBLMKD_01404 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_01405 4.1e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
APOBLMKD_01406 1e-207 bacE EGP Major facilitator Superfamily
APOBLMKD_01407 8.6e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
APOBLMKD_01408 1.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
APOBLMKD_01409 1.1e-146 ywfI C May function as heme-dependent peroxidase
APOBLMKD_01410 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
APOBLMKD_01411 6.2e-158 MA20_14895 S Conserved hypothetical protein 698
APOBLMKD_01412 6e-163 cysL K Transcriptional regulator
APOBLMKD_01413 1.2e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
APOBLMKD_01415 4.5e-174
APOBLMKD_01418 7.2e-167 yhcI S ABC transporter (permease)
APOBLMKD_01419 2.1e-163 V ABC transporter, ATP-binding protein
APOBLMKD_01420 3.4e-92 S membrane
APOBLMKD_01421 9.7e-52 padR K PadR family transcriptional regulator
APOBLMKD_01422 6.6e-110 rsfA_1
APOBLMKD_01423 6.9e-36 ywzC S Belongs to the UPF0741 family
APOBLMKD_01424 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
APOBLMKD_01425 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
APOBLMKD_01426 1.9e-245 yhdG_1 E C-terminus of AA_permease
APOBLMKD_01427 4.9e-67 ywhA K Transcriptional regulator
APOBLMKD_01428 1.8e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
APOBLMKD_01429 1.2e-117 ywhC S Peptidase family M50
APOBLMKD_01430 1.9e-92 ywhD S YwhD family
APOBLMKD_01431 1.8e-80
APOBLMKD_01432 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APOBLMKD_01433 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
APOBLMKD_01434 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
APOBLMKD_01437 1.3e-74 CP Membrane
APOBLMKD_01439 3.6e-31
APOBLMKD_01440 9.7e-29 ydcG K sequence-specific DNA binding
APOBLMKD_01442 4.7e-72 S aspartate phosphatase
APOBLMKD_01443 2.9e-43 ywiB S protein conserved in bacteria
APOBLMKD_01444 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
APOBLMKD_01445 5.4e-212 narK P COG2223 Nitrate nitrite transporter
APOBLMKD_01446 5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
APOBLMKD_01447 2.8e-139 ywiC S YwiC-like protein
APOBLMKD_01448 1.3e-84 arfM T cyclic nucleotide binding
APOBLMKD_01449 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOBLMKD_01450 6.9e-294 narH 1.7.5.1 C Nitrate reductase, beta
APOBLMKD_01451 1.4e-93 narJ 1.7.5.1 C nitrate reductase
APOBLMKD_01452 7.2e-121 narI 1.7.5.1 C nitrate reductase, gamma
APOBLMKD_01453 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APOBLMKD_01454 1.3e-295 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APOBLMKD_01455 0.0 ywjA V ABC transporter
APOBLMKD_01456 4.2e-43 ywjC
APOBLMKD_01457 4.9e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
APOBLMKD_01458 3.3e-217 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
APOBLMKD_01459 0.0 fadF C COG0247 Fe-S oxidoreductase
APOBLMKD_01460 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APOBLMKD_01461 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APOBLMKD_01462 7.1e-92 ywjG S Domain of unknown function (DUF2529)
APOBLMKD_01463 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
APOBLMKD_01464 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
APOBLMKD_01465 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
APOBLMKD_01466 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APOBLMKD_01467 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
APOBLMKD_01468 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
APOBLMKD_01469 1.1e-32 rpmE J Binds the 23S rRNA
APOBLMKD_01470 4.6e-103 tdk 2.7.1.21 F thymidine kinase
APOBLMKD_01471 0.0 sfcA 1.1.1.38 C malic enzyme
APOBLMKD_01472 6.8e-157 ywkB S Membrane transport protein
APOBLMKD_01473 2.8e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
APOBLMKD_01474 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOBLMKD_01475 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APOBLMKD_01476 9.8e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APOBLMKD_01478 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
APOBLMKD_01479 8.9e-119 spoIIR S stage II sporulation protein R
APOBLMKD_01480 4.4e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
APOBLMKD_01481 3.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APOBLMKD_01482 1.3e-83 mntP P Probably functions as a manganese efflux pump
APOBLMKD_01483 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APOBLMKD_01484 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
APOBLMKD_01485 2.2e-96 ywlG S Belongs to the UPF0340 family
APOBLMKD_01486 7.3e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APOBLMKD_01487 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APOBLMKD_01488 2.1e-61 atpI S ATP synthase
APOBLMKD_01489 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
APOBLMKD_01490 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APOBLMKD_01491 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APOBLMKD_01492 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APOBLMKD_01493 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APOBLMKD_01494 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APOBLMKD_01495 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APOBLMKD_01496 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
APOBLMKD_01497 2.5e-88 ywmA
APOBLMKD_01498 4.8e-32 ywzB S membrane
APOBLMKD_01499 2.2e-134 ywmB S TATA-box binding
APOBLMKD_01500 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APOBLMKD_01501 4e-179 spoIID D Stage II sporulation protein D
APOBLMKD_01502 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
APOBLMKD_01503 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
APOBLMKD_01505 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
APOBLMKD_01506 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APOBLMKD_01507 2.8e-93 S response regulator aspartate phosphatase
APOBLMKD_01508 2.3e-81 ywmF S Peptidase M50
APOBLMKD_01509 3.2e-10 csbD K CsbD-like
APOBLMKD_01510 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
APOBLMKD_01511 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
APOBLMKD_01512 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
APOBLMKD_01513 6.1e-67 ywnA K Transcriptional regulator
APOBLMKD_01515 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
APOBLMKD_01516 1.2e-51 ywnC S Family of unknown function (DUF5362)
APOBLMKD_01517 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APOBLMKD_01518 4.2e-69 ywnF S Family of unknown function (DUF5392)
APOBLMKD_01519 1.2e-10 ywnC S Family of unknown function (DUF5362)
APOBLMKD_01520 9.2e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
APOBLMKD_01521 1.4e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
APOBLMKD_01522 8.1e-70 ywnJ S VanZ like family
APOBLMKD_01523 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
APOBLMKD_01524 5.1e-207 ftsW D Belongs to the SEDS family
APOBLMKD_01525 2e-58 nrgB K Belongs to the P(II) protein family
APOBLMKD_01526 9.3e-228 amt P Ammonium transporter
APOBLMKD_01527 4.8e-102 phzA Q Isochorismatase family
APOBLMKD_01528 1.6e-244 ywoD EGP Major facilitator superfamily
APOBLMKD_01529 4.6e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
APOBLMKD_01530 1.4e-212 ywoG EGP Major facilitator Superfamily
APOBLMKD_01531 2.5e-71 ywoH K transcriptional
APOBLMKD_01532 1.8e-44 spoIIID K Stage III sporulation protein D
APOBLMKD_01533 2.7e-180 mbl D Rod shape-determining protein
APOBLMKD_01534 3.2e-128 flhO N flagellar basal body
APOBLMKD_01535 7e-142 flhP N flagellar basal body
APOBLMKD_01536 5.2e-198 S aspartate phosphatase
APOBLMKD_01537 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APOBLMKD_01538 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APOBLMKD_01539 2.5e-68 ywpF S YwpF-like protein
APOBLMKD_01540 4e-62 ywpG
APOBLMKD_01541 3.7e-57 ssbB L Single-stranded DNA-binding protein
APOBLMKD_01542 7.5e-138 glcR K DeoR C terminal sensor domain
APOBLMKD_01543 1.7e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
APOBLMKD_01544 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
APOBLMKD_01545 1.7e-306 ywqB S SWIM zinc finger
APOBLMKD_01546 1.3e-14
APOBLMKD_01547 1.8e-109 ywqC M biosynthesis protein
APOBLMKD_01548 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
APOBLMKD_01549 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
APOBLMKD_01550 1.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APOBLMKD_01551 5.3e-147 ywqG S Domain of unknown function (DUF1963)
APOBLMKD_01552 1.4e-21 S Domain of unknown function (DUF5082)
APOBLMKD_01553 4.3e-37 ywqI S Family of unknown function (DUF5344)
APOBLMKD_01554 3e-307 ywqJ S Pre-toxin TG
APOBLMKD_01556 9.7e-14
APOBLMKD_01557 8.4e-131 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
APOBLMKD_01558 9e-156 K Transcriptional regulator
APOBLMKD_01559 1.5e-92 ywqN S NAD(P)H-dependent
APOBLMKD_01561 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
APOBLMKD_01562 4.3e-101 ywrB P Chromate transporter
APOBLMKD_01563 2.5e-83 ywrC K Transcriptional regulator
APOBLMKD_01564 1.4e-300 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
APOBLMKD_01566 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APOBLMKD_01567 2e-09
APOBLMKD_01568 1.1e-211 cotH M Spore Coat
APOBLMKD_01569 6.2e-128 cotB
APOBLMKD_01570 7.5e-126 ywrJ
APOBLMKD_01571 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APOBLMKD_01573 2.6e-166 alsR K LysR substrate binding domain
APOBLMKD_01574 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
APOBLMKD_01575 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
APOBLMKD_01576 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
APOBLMKD_01577 1.5e-89 batE T Sh3 type 3 domain protein
APOBLMKD_01578 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
APOBLMKD_01579 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
APOBLMKD_01580 7.1e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
APOBLMKD_01581 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APOBLMKD_01582 4.5e-155 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APOBLMKD_01583 5e-179 rbsR K transcriptional
APOBLMKD_01584 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
APOBLMKD_01585 1.4e-190 gerKB E Spore germination protein
APOBLMKD_01586 4.8e-186 gerKA EG Spore germination protein
APOBLMKD_01587 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
APOBLMKD_01588 2.3e-70 pgsC S biosynthesis protein
APOBLMKD_01589 2.8e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
APOBLMKD_01590 1.3e-20 ywtC
APOBLMKD_01591 2.1e-235 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APOBLMKD_01592 2.9e-35 yttA 2.7.13.3 S Pfam Transposase IS66
APOBLMKD_01593 1.8e-156 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
APOBLMKD_01594 7.2e-178 ywtF K Transcriptional regulator
APOBLMKD_01595 4.9e-249 ywtG EGP Major facilitator Superfamily
APOBLMKD_01596 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
APOBLMKD_01597 1.1e-209 gerAC S Spore germination protein
APOBLMKD_01598 3e-196 gerBB E Spore germination protein
APOBLMKD_01599 9.7e-264 gerBA EG Spore germination protein
APOBLMKD_01600 7.7e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
APOBLMKD_01601 3e-239 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APOBLMKD_01602 5.5e-217 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APOBLMKD_01603 3.8e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
APOBLMKD_01604 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
APOBLMKD_01605 7.8e-280 M Glycosyltransferase like family 2
APOBLMKD_01606 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APOBLMKD_01607 1.7e-151 tagG GM Transport permease protein
APOBLMKD_01608 1.1e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
APOBLMKD_01609 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APOBLMKD_01610 2e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APOBLMKD_01611 8.5e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
APOBLMKD_01612 2.3e-48
APOBLMKD_01613 0.0 lytB 3.5.1.28 D Stage II sporulation protein
APOBLMKD_01614 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOBLMKD_01615 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APOBLMKD_01616 6.1e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOBLMKD_01617 2.3e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
APOBLMKD_01618 6.9e-248 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APOBLMKD_01619 8.9e-254 tuaE M Teichuronic acid biosynthesis protein
APOBLMKD_01620 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
APOBLMKD_01621 3.4e-143 tuaG GT2 M Glycosyltransferase like family 2
APOBLMKD_01622 3.9e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
APOBLMKD_01623 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
APOBLMKD_01624 6e-166 yvhJ K Transcriptional regulator
APOBLMKD_01625 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
APOBLMKD_01626 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
APOBLMKD_01627 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOBLMKD_01628 2.7e-157 degV S protein conserved in bacteria
APOBLMKD_01629 1.1e-253 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
APOBLMKD_01630 8.2e-42 comFB S Late competence development protein ComFB
APOBLMKD_01631 2.9e-76 comFC S Phosphoribosyl transferase domain
APOBLMKD_01632 4.1e-74 yvyF S flagellar protein
APOBLMKD_01633 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
APOBLMKD_01634 8.9e-81 flgN NOU FlgN protein
APOBLMKD_01635 1.4e-273 flgK N flagellar hook-associated protein
APOBLMKD_01636 2.3e-162 flgL N Belongs to the bacterial flagellin family
APOBLMKD_01637 8.9e-80 yviE
APOBLMKD_01638 1e-72 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
APOBLMKD_01639 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
APOBLMKD_01640 2e-103 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APOBLMKD_01641 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
APOBLMKD_01642 1.5e-65 fliS N flagellar protein FliS
APOBLMKD_01643 3.5e-10 fliT S bacterial-type flagellum organization
APOBLMKD_01644 6.8e-68
APOBLMKD_01645 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APOBLMKD_01646 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APOBLMKD_01647 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APOBLMKD_01648 3e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
APOBLMKD_01649 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
APOBLMKD_01650 2.3e-122 ftsE D cell division ATP-binding protein FtsE
APOBLMKD_01651 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
APOBLMKD_01652 8.6e-225 ywoF P Right handed beta helix region
APOBLMKD_01653 2.8e-252 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
APOBLMKD_01654 1.5e-55 swrA S Swarming motility protein
APOBLMKD_01655 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APOBLMKD_01656 4.1e-24 yuaB
APOBLMKD_01657 9.6e-226 yvkA EGP Major facilitator Superfamily
APOBLMKD_01658 7e-110 yvkB K Transcriptional regulator
APOBLMKD_01659 0.0 yvkC 2.7.9.2 GT Phosphotransferase
APOBLMKD_01660 7.6e-33 csbA S protein conserved in bacteria
APOBLMKD_01661 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APOBLMKD_01662 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APOBLMKD_01663 2.2e-32 yvkN
APOBLMKD_01664 6.1e-49 yvlA
APOBLMKD_01665 1.2e-165 yvlB S Putative adhesin
APOBLMKD_01666 9.6e-26 pspB KT PspC domain
APOBLMKD_01667 1.5e-40 yvlD S Membrane
APOBLMKD_01668 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
APOBLMKD_01669 4.4e-103 yxaF K Transcriptional regulator
APOBLMKD_01670 2.3e-133 yvoA K transcriptional
APOBLMKD_01671 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APOBLMKD_01672 5.7e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
APOBLMKD_01673 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APOBLMKD_01674 1.5e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APOBLMKD_01675 2.9e-111 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
APOBLMKD_01676 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
APOBLMKD_01677 3.5e-137 yvpB NU protein conserved in bacteria
APOBLMKD_01678 1e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APOBLMKD_01679 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APOBLMKD_01680 1.4e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APOBLMKD_01681 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
APOBLMKD_01682 1.6e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APOBLMKD_01683 6e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APOBLMKD_01684 1.7e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APOBLMKD_01685 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
APOBLMKD_01686 0.0 msbA2 3.6.3.44 V ABC transporter
APOBLMKD_01687 6.8e-54
APOBLMKD_01688 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_01689 2.3e-190 sasA T Histidine kinase
APOBLMKD_01690 2.5e-275 S COG0457 FOG TPR repeat
APOBLMKD_01691 1.3e-124 usp CBM50 M protein conserved in bacteria
APOBLMKD_01692 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APOBLMKD_01693 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
APOBLMKD_01694 1.1e-166 rapZ S Displays ATPase and GTPase activities
APOBLMKD_01695 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
APOBLMKD_01696 5.3e-170 whiA K May be required for sporulation
APOBLMKD_01697 4.7e-36 crh G Phosphocarrier protein Chr
APOBLMKD_01698 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
APOBLMKD_01699 8.2e-79 M Ribonuclease
APOBLMKD_01700 6.2e-182 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOBLMKD_01701 2.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
APOBLMKD_01702 7.3e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
APOBLMKD_01703 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
APOBLMKD_01704 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
APOBLMKD_01705 7.8e-247 EGP Sugar (and other) transporter
APOBLMKD_01706 1.4e-209 yraM S PrpF protein
APOBLMKD_01707 6.7e-164 yraN K Transcriptional regulator
APOBLMKD_01708 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APOBLMKD_01709 7.3e-183 scrR K transcriptional
APOBLMKD_01710 2.3e-218 rafB P LacY proton/sugar symporter
APOBLMKD_01711 1e-292 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
APOBLMKD_01713 2.6e-33
APOBLMKD_01714 3.2e-267 I Pfam Lipase (class 3)
APOBLMKD_01715 9.8e-18 S Protein of unknown function (DUF1433)
APOBLMKD_01716 1.9e-16 S Protein of unknown function (DUF1433)
APOBLMKD_01717 7.7e-16 S Protein of unknown function (DUF1433)
APOBLMKD_01718 1.6e-93 padC Q Phenolic acid decarboxylase
APOBLMKD_01719 3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOBLMKD_01720 2.2e-111 yyaS S Membrane
APOBLMKD_01721 3.7e-96 ywjB H RibD C-terminal domain
APOBLMKD_01723 3.8e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
APOBLMKD_01724 1.9e-77 slr K transcriptional
APOBLMKD_01725 1.6e-118 ywqC M biosynthesis protein
APOBLMKD_01726 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
APOBLMKD_01727 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
APOBLMKD_01728 3.3e-219 epsD GT4 M Glycosyl transferase 4-like
APOBLMKD_01729 2.6e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APOBLMKD_01730 4.7e-213 epsF GT4 M Glycosyl transferases group 1
APOBLMKD_01731 7.7e-205 epsG S EpsG family
APOBLMKD_01732 1.9e-192 epsH GT2 S Glycosyltransferase like family 2
APOBLMKD_01733 1.4e-203 epsI GM pyruvyl transferase
APOBLMKD_01734 2.7e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
APOBLMKD_01735 5.9e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOBLMKD_01736 1.1e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APOBLMKD_01737 5.4e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
APOBLMKD_01738 8.2e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
APOBLMKD_01739 9.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
APOBLMKD_01740 2.7e-32 yvfG S YvfG protein
APOBLMKD_01741 1.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
APOBLMKD_01742 3.8e-304 yvfH C L-lactate permease
APOBLMKD_01743 6.6e-120 yvfI K COG2186 Transcriptional regulators
APOBLMKD_01744 2.7e-219 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOBLMKD_01745 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APOBLMKD_01746 1.8e-270 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
APOBLMKD_01747 2.8e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APOBLMKD_01748 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
APOBLMKD_01749 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
APOBLMKD_01750 5e-151 ybbH_1 K RpiR family transcriptional regulator
APOBLMKD_01752 1.1e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
APOBLMKD_01753 1.7e-157 yvbV EG EamA-like transporter family
APOBLMKD_01754 2.4e-156 yvbU K Transcriptional regulator
APOBLMKD_01756 8.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOBLMKD_01757 5.5e-203 araR K transcriptional
APOBLMKD_01758 2.1e-252 araE EGP Major facilitator Superfamily
APOBLMKD_01760 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APOBLMKD_01761 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APOBLMKD_01762 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
APOBLMKD_01763 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APOBLMKD_01764 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
APOBLMKD_01765 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APOBLMKD_01766 5.8e-236 ywaD 3.4.11.10, 3.4.11.6 S PA domain
APOBLMKD_01767 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APOBLMKD_01768 2.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
APOBLMKD_01769 2e-169 5.1.3.2 M GDP-mannose 4,6 dehydratase
APOBLMKD_01770 8.5e-224 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
APOBLMKD_01771 4.6e-147 M Protein involved in cellulose biosynthesis
APOBLMKD_01772 2.1e-142 C WbqC-like protein family
APOBLMKD_01773 7e-124 S GlcNAc-PI de-N-acetylase
APOBLMKD_01774 3.3e-177
APOBLMKD_01775 1.8e-210 EGP Major facilitator Superfamily
APOBLMKD_01776 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
APOBLMKD_01777 0.0 tcaA S response to antibiotic
APOBLMKD_01778 1.7e-120 exoY M Membrane
APOBLMKD_01779 9.8e-104 yvbG U UPF0056 membrane protein
APOBLMKD_01780 3.5e-97 yvbF K Belongs to the GbsR family
APOBLMKD_01781 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APOBLMKD_01782 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
APOBLMKD_01783 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APOBLMKD_01784 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
APOBLMKD_01785 4.3e-76 yvbF K Belongs to the GbsR family
APOBLMKD_01786 2.5e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APOBLMKD_01787 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
APOBLMKD_01788 3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APOBLMKD_01789 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
APOBLMKD_01790 3.5e-126 mutF V ABC transporter, ATP-binding protein
APOBLMKD_01791 4.9e-123 spaE S ABC-2 family transporter protein
APOBLMKD_01792 3.1e-136 mutG S ABC-2 family transporter protein
APOBLMKD_01793 1.4e-121 K Transcriptional regulatory protein, C terminal
APOBLMKD_01794 1.5e-258 T His Kinase A (phosphoacceptor) domain
APOBLMKD_01795 8.8e-53 yodB K transcriptional
APOBLMKD_01796 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
APOBLMKD_01797 1e-69 K transcriptional
APOBLMKD_01798 6e-35 yvzC K Transcriptional
APOBLMKD_01799 4.8e-24 secG U Preprotein translocase subunit SecG
APOBLMKD_01800 1.6e-142 est 3.1.1.1 S Carboxylesterase
APOBLMKD_01801 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APOBLMKD_01802 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
APOBLMKD_01804 3.7e-48 yrdF K ribonuclease inhibitor
APOBLMKD_01805 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOBLMKD_01806 2.5e-161 ytlI K LysR substrate binding domain
APOBLMKD_01807 3e-101 ytmI K Acetyltransferase (GNAT) domain
APOBLMKD_01808 3.9e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
APOBLMKD_01809 1.3e-145 tcyK M Bacterial periplasmic substrate-binding proteins
APOBLMKD_01810 5.9e-121 tcyL P Binding-protein-dependent transport system inner membrane component
APOBLMKD_01811 1.1e-119 tcyM U Binding-protein-dependent transport system inner membrane component
APOBLMKD_01812 9.5e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APOBLMKD_01813 3.2e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOBLMKD_01814 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
APOBLMKD_01815 2.4e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOBLMKD_01817 2.8e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APOBLMKD_01818 4.6e-191 yvaA 1.1.1.371 S Oxidoreductase
APOBLMKD_01819 1.4e-47 csoR S transcriptional
APOBLMKD_01820 2.6e-29 copZ P Heavy-metal-associated domain
APOBLMKD_01821 0.0 copA 3.6.3.54 P P-type ATPase
APOBLMKD_01822 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
APOBLMKD_01823 2.3e-98 bdbD O Thioredoxin
APOBLMKD_01824 6e-73 bdbC O Required for disulfide bond formation in some proteins
APOBLMKD_01825 3.7e-140 S Metallo-peptidase family M12
APOBLMKD_01826 2.9e-97 yvgT S membrane
APOBLMKD_01827 0.0 helD 3.6.4.12 L DNA helicase
APOBLMKD_01828 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APOBLMKD_01829 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
APOBLMKD_01830 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
APOBLMKD_01831 2.7e-85 yvgO
APOBLMKD_01832 5e-156 yvgN S reductase
APOBLMKD_01833 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
APOBLMKD_01834 1.3e-191 yfiM V ABC-2 type transporter
APOBLMKD_01835 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
APOBLMKD_01836 4.3e-179 T Histidine kinase
APOBLMKD_01837 9.1e-113 yfiK K Regulator
APOBLMKD_01838 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
APOBLMKD_01839 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
APOBLMKD_01840 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
APOBLMKD_01841 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APOBLMKD_01842 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
APOBLMKD_01843 5.2e-13 S Small spore protein J (Spore_SspJ)
APOBLMKD_01844 7e-235 yvsH E Arginine ornithine antiporter
APOBLMKD_01845 1.1e-127 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
APOBLMKD_01846 4e-178 fhuD P ABC transporter
APOBLMKD_01847 1.1e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_01848 1e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_01849 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
APOBLMKD_01850 9.3e-66 yvrL S Regulatory protein YrvL
APOBLMKD_01851 7.8e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
APOBLMKD_01852 6.1e-15 S YvrJ protein family
APOBLMKD_01853 8.4e-102 yvrI K RNA polymerase
APOBLMKD_01854 1.1e-36
APOBLMKD_01855 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_01856 0.0 T PhoQ Sensor
APOBLMKD_01857 4.2e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
APOBLMKD_01858 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOBLMKD_01859 4.6e-166 yvrC P ABC transporter substrate-binding protein
APOBLMKD_01860 5.8e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOBLMKD_01861 3.6e-219 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
APOBLMKD_01862 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
APOBLMKD_01863 2.4e-226 yvqJ EGP Major facilitator Superfamily
APOBLMKD_01864 2.4e-44 liaI S membrane
APOBLMKD_01865 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
APOBLMKD_01866 1.3e-125 liaG S Putative adhesin
APOBLMKD_01867 1.9e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
APOBLMKD_01868 2.3e-193 vraS 2.7.13.3 T Histidine kinase
APOBLMKD_01869 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOBLMKD_01870 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
APOBLMKD_01871 3.6e-186 gerAB E Spore germination protein
APOBLMKD_01872 3.5e-258 gerAA EG Spore germination protein
APOBLMKD_01873 6.6e-24 S Protein of unknown function (DUF3970)
APOBLMKD_01874 1.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APOBLMKD_01875 3.2e-156 yuxN K Transcriptional regulator
APOBLMKD_01876 3.4e-24
APOBLMKD_01877 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
APOBLMKD_01878 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_01879 3.8e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APOBLMKD_01880 4.7e-79 dps P Belongs to the Dps family
APOBLMKD_01881 1.1e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOBLMKD_01882 0.0 pepF2 E COG1164 Oligoendopeptidase F
APOBLMKD_01883 7.2e-45 S YusW-like protein
APOBLMKD_01884 3.1e-150 yusV 3.6.3.34 HP ABC transporter
APOBLMKD_01885 3.3e-39 yusU S Protein of unknown function (DUF2573)
APOBLMKD_01886 1.1e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APOBLMKD_01887 1.2e-137 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
APOBLMKD_01888 1e-154 ywbI2 K Transcriptional regulator
APOBLMKD_01889 8.1e-288 yusP P Major facilitator superfamily
APOBLMKD_01890 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
APOBLMKD_01891 1.1e-53 yusN M Coat F domain
APOBLMKD_01892 5.7e-42
APOBLMKD_01893 8.9e-210 yusP P Major facilitator superfamily
APOBLMKD_01894 8.4e-165 fadM E Proline dehydrogenase
APOBLMKD_01895 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
APOBLMKD_01896 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
APOBLMKD_01897 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
APOBLMKD_01898 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
APOBLMKD_01899 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
APOBLMKD_01900 1.1e-39 yusG S Protein of unknown function (DUF2553)
APOBLMKD_01901 1.2e-61 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
APOBLMKD_01902 1.6e-54 yusE CO Thioredoxin
APOBLMKD_01903 1.5e-56 yusD S SCP-2 sterol transfer family
APOBLMKD_01904 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APOBLMKD_01905 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
APOBLMKD_01906 3e-145 metQ P Belongs to the NlpA lipoprotein family
APOBLMKD_01907 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APOBLMKD_01908 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
APOBLMKD_01909 1.2e-244 sufD O assembly protein SufD
APOBLMKD_01910 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APOBLMKD_01911 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
APOBLMKD_01912 8.7e-270 sufB O FeS cluster assembly
APOBLMKD_01913 1e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
APOBLMKD_01914 3.1e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
APOBLMKD_01915 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
APOBLMKD_01917 9.5e-164 K helix_turn_helix, mercury resistance
APOBLMKD_01918 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
APOBLMKD_01919 1.4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
APOBLMKD_01920 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
APOBLMKD_01921 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
APOBLMKD_01922 9e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
APOBLMKD_01923 3.6e-134 yurK K UTRA
APOBLMKD_01924 5.4e-206 msmX P Belongs to the ABC transporter superfamily
APOBLMKD_01925 4.7e-165 bsn L Ribonuclease
APOBLMKD_01926 3.1e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
APOBLMKD_01927 3.7e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
APOBLMKD_01928 4.1e-212 blt EGP Major facilitator Superfamily
APOBLMKD_01930 3.2e-08 S Phage Mu protein F like protein
APOBLMKD_01932 2.2e-301 pucR QT COG2508 Regulator of polyketide synthase expression
APOBLMKD_01933 1e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
APOBLMKD_01934 2.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
APOBLMKD_01935 1.5e-168 yunF S Protein of unknown function DUF72
APOBLMKD_01936 1.1e-144 yunE S membrane transporter protein
APOBLMKD_01937 3.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
APOBLMKD_01938 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
APOBLMKD_01939 1.5e-191 lytH M Peptidase, M23
APOBLMKD_01940 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
APOBLMKD_01941 1.7e-47 yutD S protein conserved in bacteria
APOBLMKD_01942 6.8e-72 yutE S Protein of unknown function DUF86
APOBLMKD_01943 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APOBLMKD_01944 2.5e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
APOBLMKD_01945 3e-195 yutH S Spore coat protein
APOBLMKD_01946 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
APOBLMKD_01947 4.9e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
APOBLMKD_01948 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APOBLMKD_01949 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
APOBLMKD_01950 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
APOBLMKD_01951 1.1e-53 yuzD S protein conserved in bacteria
APOBLMKD_01952 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
APOBLMKD_01953 2.4e-39 yuzB S Belongs to the UPF0349 family
APOBLMKD_01954 0.0 Q Polyketide synthase of type I
APOBLMKD_01955 0.0 1.1.1.320 Q Polyketide synthase of type I
APOBLMKD_01956 0.0 pksJ Q Polyketide synthase of type I
APOBLMKD_01957 1.3e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
APOBLMKD_01958 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
APOBLMKD_01959 5.5e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
APOBLMKD_01960 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
APOBLMKD_01961 9.6e-189 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APOBLMKD_01962 0.0 ydiF S ABC transporter
APOBLMKD_01963 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
APOBLMKD_01964 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APOBLMKD_01965 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APOBLMKD_01966 9.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APOBLMKD_01967 1.7e-27 ydiK S Domain of unknown function (DUF4305)
APOBLMKD_01968 4.3e-127 ydiL S CAAX protease self-immunity
APOBLMKD_01969 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APOBLMKD_01970 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APOBLMKD_01971 7.2e-24 S Protein of unknown function (DUF4064)
APOBLMKD_01972 0.0 K NB-ARC domain
APOBLMKD_01973 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
APOBLMKD_01974 4.9e-249 gutA G MFS/sugar transport protein
APOBLMKD_01975 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
APOBLMKD_01976 3.6e-30 yjdJ S Domain of unknown function (DUF4306)
APOBLMKD_01977 3.3e-113 pspA KT Phage shock protein A
APOBLMKD_01978 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APOBLMKD_01979 3.8e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
APOBLMKD_01980 4.1e-144 ydjI S virion core protein (lumpy skin disease virus)
APOBLMKD_01981 0.0 yrhL I Acyltransferase family
APOBLMKD_01982 1.4e-145 rsiV S Protein of unknown function (DUF3298)
APOBLMKD_01983 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
APOBLMKD_01984 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
APOBLMKD_01985 1.2e-61 ydjM M Lytic transglycolase
APOBLMKD_01986 1.5e-133 ydjN U Involved in the tonB-independent uptake of proteins
APOBLMKD_01988 7.2e-35 ydjO S Cold-inducible protein YdjO
APOBLMKD_01989 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
APOBLMKD_01990 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
APOBLMKD_01991 6.6e-176 yeaC S COG0714 MoxR-like ATPases
APOBLMKD_01992 1.9e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
APOBLMKD_01993 0.0 yebA E COG1305 Transglutaminase-like enzymes
APOBLMKD_01994 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
APOBLMKD_01995 1.9e-92 sigV K Belongs to the sigma-70 factor family. ECF subfamily
APOBLMKD_01996 2.5e-248 S Domain of unknown function (DUF4179)
APOBLMKD_01997 8.1e-209 pbuG S permease
APOBLMKD_01998 1.5e-125 yebC M Membrane
APOBLMKD_02000 7.5e-92 yebE S UPF0316 protein
APOBLMKD_02001 5.5e-29 yebG S NETI protein
APOBLMKD_02002 6.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APOBLMKD_02003 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APOBLMKD_02004 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APOBLMKD_02005 5.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
APOBLMKD_02006 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOBLMKD_02007 7.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOBLMKD_02008 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOBLMKD_02009 3.1e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APOBLMKD_02010 6.4e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
APOBLMKD_02011 2.7e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APOBLMKD_02012 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
APOBLMKD_02013 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
APOBLMKD_02014 2.6e-25 S Protein of unknown function (DUF2892)
APOBLMKD_02015 0.0 yerA 3.5.4.2 F adenine deaminase
APOBLMKD_02016 5.2e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
APOBLMKD_02017 2.4e-50 yerC S protein conserved in bacteria
APOBLMKD_02018 1.8e-300 yerD 1.4.7.1 E Belongs to the glutamate synthase family
APOBLMKD_02019 2e-126 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
APOBLMKD_02020 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
APOBLMKD_02021 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APOBLMKD_02022 1.3e-221 camS S COG4851 Protein involved in sex pheromone biosynthesis
APOBLMKD_02023 1.2e-191 yerI S homoserine kinase type II (protein kinase fold)
APOBLMKD_02024 5.7e-121 sapB S MgtC SapB transporter
APOBLMKD_02025 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOBLMKD_02026 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APOBLMKD_02027 1e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APOBLMKD_02028 1.7e-268 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APOBLMKD_02029 1.4e-150 yerO K Transcriptional regulator
APOBLMKD_02030 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APOBLMKD_02031 1.1e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APOBLMKD_02032 2.4e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APOBLMKD_02033 8.1e-311 L Uncharacterized conserved protein (DUF2075)
APOBLMKD_02034 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
APOBLMKD_02035 2.2e-138 cylB V ABC-2 type transporter
APOBLMKD_02036 1.3e-60 S Protein of unknown function, DUF600
APOBLMKD_02037 2.1e-50 S Protein of unknown function, DUF600
APOBLMKD_02038 4e-46 S Protein of unknown function, DUF600
APOBLMKD_02039 1e-40 S Protein of unknown function, DUF600
APOBLMKD_02040 4.8e-79 S Protein of unknown function, DUF600
APOBLMKD_02041 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
APOBLMKD_02042 2.9e-07
APOBLMKD_02044 3e-41 U Preprotein translocase subunit SecB
APOBLMKD_02045 8.7e-31
APOBLMKD_02046 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_02047 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_02050 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
APOBLMKD_02051 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
APOBLMKD_02052 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APOBLMKD_02053 1.3e-223 ybbR S protein conserved in bacteria
APOBLMKD_02054 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APOBLMKD_02055 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APOBLMKD_02056 6.4e-154 V ATPases associated with a variety of cellular activities
APOBLMKD_02057 4.1e-105 S ABC-2 family transporter protein
APOBLMKD_02058 9.6e-163 dkgB S Aldo/keto reductase family
APOBLMKD_02059 2.9e-93 yxaC M effector of murein hydrolase
APOBLMKD_02060 6.9e-52 S LrgA family
APOBLMKD_02061 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_02062 2e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
APOBLMKD_02063 1.5e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
APOBLMKD_02064 6.2e-104 T Histidine kinase
APOBLMKD_02065 3.8e-82 KT helix_turn_helix, Lux Regulon
APOBLMKD_02066 3.5e-134 V ABC transporter, ATP-binding protein
APOBLMKD_02067 6.8e-146 V ABC-2 type transporter
APOBLMKD_02068 6e-123 V ABC-2 type transporter
APOBLMKD_02069 4.4e-14
APOBLMKD_02070 1.1e-58 bacT Q Thioesterase domain
APOBLMKD_02071 7e-181 yaaC S YaaC-like Protein
APOBLMKD_02072 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
APOBLMKD_02073 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
APOBLMKD_02074 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
APOBLMKD_02075 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
APOBLMKD_02076 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APOBLMKD_02077 1.8e-168 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
APOBLMKD_02078 1.3e-09
APOBLMKD_02079 4.5e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
APOBLMKD_02080 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
APOBLMKD_02081 3.8e-211 yaaH M Glycoside Hydrolase Family
APOBLMKD_02082 1.8e-98 yaaI Q COG1335 Amidases related to nicotinamidase
APOBLMKD_02083 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APOBLMKD_02084 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APOBLMKD_02085 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APOBLMKD_02086 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APOBLMKD_02087 3.6e-32 yaaL S Protein of unknown function (DUF2508)
APOBLMKD_02088 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
APOBLMKD_02091 2e-22
APOBLMKD_02093 1.1e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APOBLMKD_02094 5.6e-211 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APOBLMKD_02095 3.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
APOBLMKD_02096 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
APOBLMKD_02097 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOBLMKD_02099 2.7e-35 K SpoVT / AbrB like domain
APOBLMKD_02100 6.4e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
APOBLMKD_02101 1.7e-123 S ABC-2 type transporter
APOBLMKD_02102 1.3e-139 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
APOBLMKD_02103 1.3e-35
APOBLMKD_02104 0.0 yjcD 3.6.4.12 L DNA helicase
APOBLMKD_02105 3.8e-38 spoVIF S Stage VI sporulation protein F
APOBLMKD_02109 5.6e-56 yjcA S Protein of unknown function (DUF1360)
APOBLMKD_02110 1.4e-52 cotV S Spore Coat Protein X and V domain
APOBLMKD_02111 6.8e-21 cotW
APOBLMKD_02112 5.1e-71 cotX S Spore Coat Protein X and V domain
APOBLMKD_02113 4.6e-93 cotY S Spore coat protein Z
APOBLMKD_02114 6.7e-83 cotZ S Spore coat protein
APOBLMKD_02115 1.5e-88 yjbX S Spore coat protein
APOBLMKD_02116 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
APOBLMKD_02117 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APOBLMKD_02118 1.1e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APOBLMKD_02119 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
APOBLMKD_02120 6.7e-30 thiS H Thiamine biosynthesis
APOBLMKD_02121 2.8e-210 thiO 1.4.3.19 E Glycine oxidase
APOBLMKD_02122 3.5e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
APOBLMKD_02123 4.9e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APOBLMKD_02124 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APOBLMKD_02125 1.2e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
APOBLMKD_02126 4.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APOBLMKD_02127 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APOBLMKD_02128 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
APOBLMKD_02129 8.6e-60 yjbL S Belongs to the UPF0738 family
APOBLMKD_02130 1.5e-95 yjbK S protein conserved in bacteria
APOBLMKD_02131 1.2e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APOBLMKD_02132 4.8e-72 yjbI S Bacterial-like globin
APOBLMKD_02133 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
APOBLMKD_02134 5.8e-19
APOBLMKD_02135 0.0 pepF E oligoendopeptidase F
APOBLMKD_02136 2.3e-215 yjbF S Competence protein
APOBLMKD_02137 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APOBLMKD_02138 1.1e-108 yjbE P Integral membrane protein TerC family
APOBLMKD_02139 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APOBLMKD_02140 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOBLMKD_02141 9.8e-230 S Putative glycosyl hydrolase domain
APOBLMKD_02142 2.3e-170 oppF E Belongs to the ABC transporter superfamily
APOBLMKD_02143 2.7e-202 oppD P Belongs to the ABC transporter superfamily
APOBLMKD_02144 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOBLMKD_02145 1.6e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOBLMKD_02146 0.0 oppA E ABC transporter substrate-binding protein
APOBLMKD_02147 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
APOBLMKD_02148 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_02149 0.0 srfAC Q TIGRFAM amino acid adenylation domain
APOBLMKD_02153 2e-08
APOBLMKD_02157 8.6e-87 pksJ Q Polyketide synthase of type I
APOBLMKD_02159 2.7e-14 Q calcium- and calmodulin-responsive adenylate cyclase activity
APOBLMKD_02160 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APOBLMKD_02161 1.1e-62 erpA S Belongs to the HesB IscA family
APOBLMKD_02162 2.4e-136 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
APOBLMKD_02163 3.9e-26 K helix_turn_helix, mercury resistance
APOBLMKD_02165 2.2e-33 S Bacteriocin class IId cyclical uberolysin-like
APOBLMKD_02167 1.5e-121 V ABC transporter
APOBLMKD_02168 1e-69 CP Membrane
APOBLMKD_02169 4.8e-29
APOBLMKD_02170 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APOBLMKD_02172 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
APOBLMKD_02173 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
APOBLMKD_02174 9.9e-28 yuiB S Putative membrane protein
APOBLMKD_02175 2.7e-117 yuiC S protein conserved in bacteria
APOBLMKD_02176 1.6e-77 yuiD S protein conserved in bacteria
APOBLMKD_02177 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
APOBLMKD_02178 1.2e-207 yuiF S antiporter
APOBLMKD_02179 1.5e-101 bioY S Biotin biosynthesis protein
APOBLMKD_02180 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
APOBLMKD_02181 5.2e-164 besA S Putative esterase
APOBLMKD_02182 1.8e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOBLMKD_02183 4.3e-217 entC 5.4.4.2 HQ Isochorismate synthase
APOBLMKD_02184 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
APOBLMKD_02185 6.1e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
APOBLMKD_02186 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_02187 1.1e-33 mbtH S MbtH-like protein
APOBLMKD_02188 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
APOBLMKD_02189 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
APOBLMKD_02190 4.2e-228 yukF QT Transcriptional regulator
APOBLMKD_02191 3.3e-46 esxA S Belongs to the WXG100 family
APOBLMKD_02192 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
APOBLMKD_02193 1.2e-204 essB S WXG100 protein secretion system (Wss), protein YukC
APOBLMKD_02194 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
APOBLMKD_02195 0.0 esaA S type VII secretion protein EsaA
APOBLMKD_02196 1.3e-76 yueC S Family of unknown function (DUF5383)
APOBLMKD_02197 7.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_02198 8.3e-96 yueE S phosphohydrolase
APOBLMKD_02199 1.6e-22 S Protein of unknown function (DUF2642)
APOBLMKD_02200 3.6e-186 yueF S transporter activity
APOBLMKD_02201 6.4e-34 yueG S Spore germination protein gerPA/gerPF
APOBLMKD_02202 2.8e-38 yueH S YueH-like protein
APOBLMKD_02203 7.2e-68 yueI S Protein of unknown function (DUF1694)
APOBLMKD_02204 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
APOBLMKD_02205 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APOBLMKD_02206 2.5e-228 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
APOBLMKD_02207 1.2e-50 yuzC
APOBLMKD_02210 8.9e-98 comQ H Belongs to the FPP GGPP synthase family
APOBLMKD_02212 6e-276 comP 2.7.13.3 T Histidine kinase
APOBLMKD_02213 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOBLMKD_02214 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
APOBLMKD_02215 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
APOBLMKD_02216 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOBLMKD_02217 3.2e-75 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOBLMKD_02218 3.4e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOBLMKD_02219 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOBLMKD_02220 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOBLMKD_02221 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APOBLMKD_02222 2.3e-12
APOBLMKD_02223 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
APOBLMKD_02224 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
APOBLMKD_02225 5.6e-286 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
APOBLMKD_02226 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
APOBLMKD_02227 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
APOBLMKD_02228 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APOBLMKD_02229 2.7e-73 yufK S Family of unknown function (DUF5366)
APOBLMKD_02230 2.2e-72 yuxK S protein conserved in bacteria
APOBLMKD_02231 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
APOBLMKD_02232 4.5e-185 yuxJ EGP Major facilitator Superfamily
APOBLMKD_02233 4e-118 kapD L the KinA pathway to sporulation
APOBLMKD_02234 7.7e-67 kapB G Kinase associated protein B
APOBLMKD_02235 8.9e-229 T PhoQ Sensor
APOBLMKD_02236 8.7e-223 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
APOBLMKD_02237 5.4e-40 yugE S Domain of unknown function (DUF1871)
APOBLMKD_02238 5.5e-155 yugF I Hydrolase
APOBLMKD_02239 7.6e-83 alaR K Transcriptional regulator
APOBLMKD_02240 1.6e-208 yugH 2.6.1.1 E Aminotransferase
APOBLMKD_02241 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
APOBLMKD_02242 1.8e-34 yuzA S Domain of unknown function (DUF378)
APOBLMKD_02243 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
APOBLMKD_02244 1.8e-228 yugK C Dehydrogenase
APOBLMKD_02245 5.5e-118 ycaC Q Isochorismatase family
APOBLMKD_02246 9.1e-93 S NADPH-dependent FMN reductase
APOBLMKD_02247 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
APOBLMKD_02249 7e-71 yugN S YugN-like family
APOBLMKD_02250 5.3e-181 yugO P COG1226 Kef-type K transport systems
APOBLMKD_02251 6.7e-27 mstX S Membrane-integrating protein Mistic
APOBLMKD_02252 3.4e-18
APOBLMKD_02253 8.3e-117 yugP S Zn-dependent protease
APOBLMKD_02254 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
APOBLMKD_02255 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
APOBLMKD_02256 3.5e-73 yugU S Uncharacterised protein family UPF0047
APOBLMKD_02257 1.1e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
APOBLMKD_02258 1.4e-40
APOBLMKD_02259 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
APOBLMKD_02260 8.1e-221 mcpA NT chemotaxis protein
APOBLMKD_02261 2.9e-234 mcpA NT chemotaxis protein
APOBLMKD_02262 6e-224 mcpA NT chemotaxis protein
APOBLMKD_02263 1.3e-234 mcpA NT chemotaxis protein
APOBLMKD_02264 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
APOBLMKD_02265 1.4e-184 ygjR S Oxidoreductase
APOBLMKD_02266 2.9e-194 yubA S transporter activity
APOBLMKD_02267 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APOBLMKD_02269 5.4e-50 yjcN
APOBLMKD_02270 1.4e-118 G Cupin
APOBLMKD_02271 2.1e-216 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APOBLMKD_02272 1.5e-144 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APOBLMKD_02273 3.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
APOBLMKD_02274 7.9e-94 yuaB
APOBLMKD_02275 8.6e-96 yuaC K Belongs to the GbsR family
APOBLMKD_02276 2.7e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
APOBLMKD_02277 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
APOBLMKD_02278 7.1e-109 yuaD S MOSC domain
APOBLMKD_02279 6.9e-73 yuaE S DinB superfamily
APOBLMKD_02280 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
APOBLMKD_02281 1.7e-178 yuaG 3.4.21.72 S protein conserved in bacteria
APOBLMKD_02282 1.5e-95 thiT S Thiamine transporter protein (Thia_YuaJ)
APOBLMKD_02283 1.6e-52 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APOBLMKD_02288 1.6e-08
APOBLMKD_02295 1.3e-09
APOBLMKD_02296 7.8e-08
APOBLMKD_02305 6.5e-76 tspO T membrane
APOBLMKD_02306 7e-130 dksA T COG1734 DnaK suppressor protein
APOBLMKD_02307 6.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
APOBLMKD_02308 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
APOBLMKD_02309 4.7e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
APOBLMKD_02310 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APOBLMKD_02311 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
APOBLMKD_02312 1.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
APOBLMKD_02313 2e-23 S Domain of Unknown Function (DUF1540)
APOBLMKD_02314 1.5e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
APOBLMKD_02315 1.5e-239 cydA 1.10.3.14 C oxidase, subunit
APOBLMKD_02316 7.9e-41 rpmE2 J Ribosomal protein L31
APOBLMKD_02317 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
APOBLMKD_02318 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
APOBLMKD_02319 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APOBLMKD_02320 7.9e-76 ytkA S YtkA-like
APOBLMKD_02322 7.8e-76 dps P Belongs to the Dps family
APOBLMKD_02323 5e-61 ytkC S Bacteriophage holin family
APOBLMKD_02324 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
APOBLMKD_02325 1.4e-126 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APOBLMKD_02326 3.2e-144 ytlC P ABC transporter
APOBLMKD_02327 8.9e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
APOBLMKD_02328 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
APOBLMKD_02329 1.6e-38 ytmB S Protein of unknown function (DUF2584)
APOBLMKD_02330 6.5e-306 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
APOBLMKD_02331 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APOBLMKD_02332 0.0 asnB 6.3.5.4 E Asparagine synthase
APOBLMKD_02333 1.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
APOBLMKD_02334 6.7e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
APOBLMKD_02335 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
APOBLMKD_02336 7.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
APOBLMKD_02337 2.6e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
APOBLMKD_02339 2.5e-106 ytqB J Putative rRNA methylase
APOBLMKD_02340 1.1e-189 yhcC S Fe-S oxidoreductase
APOBLMKD_02341 5.3e-282 norB EGP COG0477 Permeases of the major facilitator superfamily
APOBLMKD_02342 6.8e-193 K helix_turn_helix, Arsenical Resistance Operon Repressor
APOBLMKD_02343 7.4e-40 ytzC S Protein of unknown function (DUF2524)
APOBLMKD_02345 3.9e-66 ytrA K GntR family transcriptional regulator
APOBLMKD_02346 1.9e-161 ytrB P abc transporter atp-binding protein
APOBLMKD_02347 1.3e-163 S ABC-2 family transporter protein
APOBLMKD_02348 2e-172 P ABC-2 family transporter protein
APOBLMKD_02349 1.3e-142
APOBLMKD_02350 2.2e-125 ytrE V ABC transporter, ATP-binding protein
APOBLMKD_02351 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
APOBLMKD_02352 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_02353 1.9e-170 T PhoQ Sensor
APOBLMKD_02354 4.9e-134 bceA V ABC transporter, ATP-binding protein
APOBLMKD_02355 0.0 bceB V ABC transporter (permease)
APOBLMKD_02356 1.4e-122 ywaF S Integral membrane protein
APOBLMKD_02357 1.8e-207 yttB EGP Major facilitator Superfamily
APOBLMKD_02358 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
APOBLMKD_02359 1.2e-52 ytvB S Protein of unknown function (DUF4257)
APOBLMKD_02360 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
APOBLMKD_02361 5.6e-52 ytwF P Sulfurtransferase
APOBLMKD_02362 1.7e-84 M Acetyltransferase (GNAT) domain
APOBLMKD_02363 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
APOBLMKD_02364 5.3e-142 amyC P ABC transporter (permease)
APOBLMKD_02365 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
APOBLMKD_02366 4.9e-243 msmE G Bacterial extracellular solute-binding protein
APOBLMKD_02367 4.8e-185 msmR K Transcriptional regulator
APOBLMKD_02368 9e-26 yteV S Sporulation protein Cse60
APOBLMKD_02369 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
APOBLMKD_02370 5.7e-236 ytfP S HI0933-like protein
APOBLMKD_02371 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOBLMKD_02372 2.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APOBLMKD_02373 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
APOBLMKD_02374 3.7e-128 ythP V ABC transporter
APOBLMKD_02375 1.7e-215 ythQ U Bacterial ABC transporter protein EcsB
APOBLMKD_02376 1.3e-227 pbuO S permease
APOBLMKD_02377 4e-267 pepV 3.5.1.18 E Dipeptidase
APOBLMKD_02378 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APOBLMKD_02379 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
APOBLMKD_02380 1.3e-165 ytlQ
APOBLMKD_02381 6.8e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
APOBLMKD_02382 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
APOBLMKD_02383 3.5e-45 ytzH S YtzH-like protein
APOBLMKD_02384 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APOBLMKD_02385 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
APOBLMKD_02386 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
APOBLMKD_02387 1.7e-51 ytzB S small secreted protein
APOBLMKD_02388 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
APOBLMKD_02389 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
APOBLMKD_02390 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APOBLMKD_02391 3.7e-148 ytpQ S Belongs to the UPF0354 family
APOBLMKD_02392 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APOBLMKD_02393 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
APOBLMKD_02394 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
APOBLMKD_02395 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APOBLMKD_02396 1.7e-16 ytxH S COG4980 Gas vesicle protein
APOBLMKD_02397 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
APOBLMKD_02398 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
APOBLMKD_02399 6.4e-182 ccpA K catabolite control protein A
APOBLMKD_02400 6.6e-145 motA N flagellar motor
APOBLMKD_02401 4.8e-120 motS N Flagellar motor protein
APOBLMKD_02402 4e-228 acuC BQ histone deacetylase
APOBLMKD_02403 1.3e-116 acuB S Domain in cystathionine beta-synthase and other proteins.
APOBLMKD_02404 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
APOBLMKD_02405 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APOBLMKD_02406 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APOBLMKD_02407 2.1e-46 azlD S Branched-chain amino acid transport protein (AzlD)
APOBLMKD_02408 5.2e-125 azlC E AzlC protein
APOBLMKD_02409 2.8e-148 K Transcriptional regulator
APOBLMKD_02410 3.6e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APOBLMKD_02411 2.6e-135 E GDSL-like Lipase/Acylhydrolase family
APOBLMKD_02413 2.2e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
APOBLMKD_02414 2.5e-09
APOBLMKD_02415 3e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APOBLMKD_02416 1.7e-99 yokH G SMI1 / KNR4 family
APOBLMKD_02417 5.5e-253 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
APOBLMKD_02418 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APOBLMKD_02419 2.3e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
APOBLMKD_02420 1.7e-84 ytsP 1.8.4.14 T GAF domain-containing protein
APOBLMKD_02421 7.7e-109 yttP K Transcriptional regulator
APOBLMKD_02422 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
APOBLMKD_02423 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APOBLMKD_02424 2.6e-239 braB E Component of the transport system for branched-chain amino acids
APOBLMKD_02425 3.8e-207 iscS2 2.8.1.7 E Cysteine desulfurase
APOBLMKD_02426 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APOBLMKD_02427 3.9e-31 sspB S spore protein
APOBLMKD_02428 2.1e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APOBLMKD_02429 4.4e-311 ytcJ S amidohydrolase
APOBLMKD_02430 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APOBLMKD_02431 6.4e-182 sppA OU signal peptide peptidase SppA
APOBLMKD_02432 4.5e-88 yteJ S RDD family
APOBLMKD_02433 1e-93 ytfI S Protein of unknown function (DUF2953)
APOBLMKD_02434 1.6e-60 ytfJ S Sporulation protein YtfJ
APOBLMKD_02435 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APOBLMKD_02436 2e-180 ytxK 2.1.1.72 L DNA methylase
APOBLMKD_02437 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APOBLMKD_02438 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
APOBLMKD_02439 2.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
APOBLMKD_02440 4.1e-264 argH 4.3.2.1 E argininosuccinate lyase
APOBLMKD_02442 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_02443 1.3e-128 ytkL S Belongs to the UPF0173 family
APOBLMKD_02444 1.6e-236 ytoI K transcriptional regulator containing CBS domains
APOBLMKD_02445 1.5e-46 ytpI S YtpI-like protein
APOBLMKD_02446 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
APOBLMKD_02447 5.8e-23
APOBLMKD_02448 4.3e-86 ytrI
APOBLMKD_02449 3.2e-56 ytrH S Sporulation protein YtrH
APOBLMKD_02450 0.0 dnaE 2.7.7.7 L DNA polymerase
APOBLMKD_02451 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
APOBLMKD_02452 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APOBLMKD_02453 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
APOBLMKD_02454 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APOBLMKD_02455 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
APOBLMKD_02456 3.5e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
APOBLMKD_02457 2.4e-193 ytvI S sporulation integral membrane protein YtvI
APOBLMKD_02458 1.1e-72 yeaL S membrane
APOBLMKD_02459 2.1e-46 yjdF S Protein of unknown function (DUF2992)
APOBLMKD_02460 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
APOBLMKD_02461 1.2e-241 icd 1.1.1.42 C isocitrate
APOBLMKD_02462 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
APOBLMKD_02463 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOBLMKD_02464 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
APOBLMKD_02465 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APOBLMKD_02466 3.8e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APOBLMKD_02467 2.1e-106 ytaF P Probably functions as a manganese efflux pump
APOBLMKD_02468 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APOBLMKD_02469 7.6e-160 ytbE S reductase
APOBLMKD_02470 5.8e-206 ytbD EGP Major facilitator Superfamily
APOBLMKD_02471 2e-67 ytcD K Transcriptional regulator
APOBLMKD_02472 5.1e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APOBLMKD_02473 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
APOBLMKD_02474 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APOBLMKD_02475 4.1e-251 dnaB L Membrane attachment protein
APOBLMKD_02476 9.5e-172 dnaI L Primosomal protein DnaI
APOBLMKD_02477 1.6e-106 ytxB S SNARE associated Golgi protein
APOBLMKD_02478 6.7e-153 ytxC S YtxC-like family
APOBLMKD_02479 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APOBLMKD_02480 3.5e-151 ysaA S HAD-hyrolase-like
APOBLMKD_02481 0.0 lytS 2.7.13.3 T Histidine kinase
APOBLMKD_02482 3.2e-130 lytT T COG3279 Response regulator of the LytR AlgR family
APOBLMKD_02483 2.9e-38 lrgA S effector of murein hydrolase LrgA
APOBLMKD_02484 8.4e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
APOBLMKD_02485 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APOBLMKD_02486 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
APOBLMKD_02487 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APOBLMKD_02488 1.7e-41 ysdA S Membrane
APOBLMKD_02489 1.9e-65 ysdB S Sigma-w pathway protein YsdB
APOBLMKD_02490 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
APOBLMKD_02491 1.5e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
APOBLMKD_02492 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
APOBLMKD_02493 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
APOBLMKD_02494 9.3e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
APOBLMKD_02495 1.7e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
APOBLMKD_02496 1.2e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
APOBLMKD_02497 2.9e-251 araN G carbohydrate transport
APOBLMKD_02498 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
APOBLMKD_02499 1.2e-144 araQ G transport system permease
APOBLMKD_02500 7.3e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
APOBLMKD_02501 0.0 cstA T Carbon starvation protein
APOBLMKD_02502 9.2e-253 glcF C Glycolate oxidase
APOBLMKD_02503 2e-258 glcD 1.1.3.15 C FAD binding domain
APOBLMKD_02504 5.1e-201 ysfB KT regulator
APOBLMKD_02505 2e-32 sspI S Belongs to the SspI family
APOBLMKD_02506 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APOBLMKD_02507 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APOBLMKD_02508 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APOBLMKD_02509 4.2e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APOBLMKD_02510 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APOBLMKD_02511 3.6e-83 cvpA S membrane protein, required for colicin V production
APOBLMKD_02512 0.0 polX L COG1796 DNA polymerase IV (family X)
APOBLMKD_02513 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APOBLMKD_02514 4.7e-67 yshE S membrane
APOBLMKD_02515 9.2e-116 ywbB S Protein of unknown function (DUF2711)
APOBLMKD_02516 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APOBLMKD_02517 2.7e-103 fadR K Transcriptional regulator
APOBLMKD_02518 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
APOBLMKD_02519 2.8e-137 etfB C Electron transfer flavoprotein
APOBLMKD_02520 1.2e-177 etfA C Electron transfer flavoprotein
APOBLMKD_02521 4.3e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
APOBLMKD_02522 2.5e-52 trxA O Belongs to the thioredoxin family
APOBLMKD_02523 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APOBLMKD_02524 9.2e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
APOBLMKD_02525 2e-79 yslB S Protein of unknown function (DUF2507)
APOBLMKD_02526 4.8e-108 sdhC C succinate dehydrogenase
APOBLMKD_02527 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
APOBLMKD_02528 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
APOBLMKD_02529 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
APOBLMKD_02530 2e-30 gerE K Transcriptional regulator
APOBLMKD_02531 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_02532 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APOBLMKD_02533 2.6e-197 gerM S COG5401 Spore germination protein
APOBLMKD_02534 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
APOBLMKD_02535 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APOBLMKD_02536 5.9e-91 ysnB S Phosphoesterase
APOBLMKD_02541 0.0 ilvB 2.2.1.6 E Acetolactate synthase
APOBLMKD_02542 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
APOBLMKD_02543 1.6e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
APOBLMKD_02544 7.9e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
APOBLMKD_02545 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
APOBLMKD_02546 9.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APOBLMKD_02547 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APOBLMKD_02548 3.9e-187 ysoA H Tetratricopeptide repeat
APOBLMKD_02549 6.2e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APOBLMKD_02550 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APOBLMKD_02551 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
APOBLMKD_02552 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
APOBLMKD_02553 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
APOBLMKD_02554 3.8e-87 ysxD
APOBLMKD_02555 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
APOBLMKD_02556 1e-145 hemX O cytochrome C
APOBLMKD_02557 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
APOBLMKD_02558 1.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APOBLMKD_02559 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
APOBLMKD_02560 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
APOBLMKD_02561 9.8e-224 spoVID M stage VI sporulation protein D
APOBLMKD_02562 9.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
APOBLMKD_02563 2.1e-25
APOBLMKD_02564 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APOBLMKD_02565 4.8e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APOBLMKD_02566 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
APOBLMKD_02567 2.8e-137 spoIIB S Sporulation related domain
APOBLMKD_02568 9.5e-98 maf D septum formation protein Maf
APOBLMKD_02569 3e-69 radC E Belongs to the UPF0758 family
APOBLMKD_02570 1.3e-268 S Recombinase
APOBLMKD_02571 8e-76 S Pfam:Peptidase_M78
APOBLMKD_02572 4.4e-66 S sequence-specific DNA binding
APOBLMKD_02573 5.2e-09 plcR K helix-turn-helix
APOBLMKD_02576 8.1e-23 S Uncharacterized protein YqaH
APOBLMKD_02578 5.8e-92 S DNA protection
APOBLMKD_02579 2.5e-172 S AAA domain
APOBLMKD_02581 4.8e-73 S Protein of unknown function (DUF669)
APOBLMKD_02582 0.0 S hydrolase activity
APOBLMKD_02583 9.3e-53
APOBLMKD_02584 1.9e-95 S nuclease activity
APOBLMKD_02585 1.9e-81
APOBLMKD_02587 4.4e-59
APOBLMKD_02589 1.2e-73 S regulation of transcription, DNA-dependent
APOBLMKD_02590 9.7e-20 N PFAM YcfA family protein
APOBLMKD_02592 7.7e-72 S HNH endonuclease
APOBLMKD_02593 3.9e-87 S Phage terminase, small subunit
APOBLMKD_02594 6.3e-230 S Phage Terminase
APOBLMKD_02595 1.8e-10
APOBLMKD_02596 2.7e-238 S Phage portal protein
APOBLMKD_02597 2.6e-109 S peptidase activity
APOBLMKD_02598 2.1e-179 S capsid protein
APOBLMKD_02600 1.2e-44 S peptidoglycan catabolic process
APOBLMKD_02601 5.5e-24 S Phage gp6-like head-tail connector protein
APOBLMKD_02602 2.8e-15 S Phage head-tail joining protein
APOBLMKD_02603 5.1e-47 S Bacteriophage HK97-gp10, putative tail-component
APOBLMKD_02604 3.3e-30
APOBLMKD_02605 4.9e-60
APOBLMKD_02606 9.2e-24
APOBLMKD_02607 1.5e-11
APOBLMKD_02608 0.0 S peptidoglycan catabolic process
APOBLMKD_02609 2.9e-111 S Phage tail protein
APOBLMKD_02610 1.2e-225 NU Prophage endopeptidase tail
APOBLMKD_02611 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
APOBLMKD_02612 1.5e-143 S Domain of unknown function (DUF2479)
APOBLMKD_02615 1.3e-59 S Pfam:Phage_holin_4_1
APOBLMKD_02616 8e-121 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
APOBLMKD_02620 2.4e-25
APOBLMKD_02621 1.3e-23
APOBLMKD_02622 6.7e-101
APOBLMKD_02623 8.4e-51 radC E Belongs to the UPF0758 family
APOBLMKD_02624 4e-184 mreB D Rod shape-determining protein MreB
APOBLMKD_02625 3.6e-157 mreC M Involved in formation and maintenance of cell shape
APOBLMKD_02626 5.4e-84 mreD M shape-determining protein
APOBLMKD_02627 5.4e-92 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
APOBLMKD_02628 2.3e-142 minD D Belongs to the ParA family
APOBLMKD_02629 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
APOBLMKD_02630 4.6e-160 spoIVFB S Stage IV sporulation protein
APOBLMKD_02631 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
APOBLMKD_02632 3.2e-56 ysxB J ribosomal protein
APOBLMKD_02633 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
APOBLMKD_02634 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
APOBLMKD_02635 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APOBLMKD_02636 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
APOBLMKD_02637 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
APOBLMKD_02638 1.3e-93 niaR S small molecule binding protein (contains 3H domain)
APOBLMKD_02639 9.5e-222 nifS 2.8.1.7 E Cysteine desulfurase
APOBLMKD_02640 9.7e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
APOBLMKD_02641 1e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
APOBLMKD_02642 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
APOBLMKD_02643 2.7e-126 safA M spore coat assembly protein SafA
APOBLMKD_02644 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APOBLMKD_02646 3.7e-93 bofC S BofC C-terminal domain
APOBLMKD_02647 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APOBLMKD_02648 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APOBLMKD_02649 1.6e-20 yrzS S Protein of unknown function (DUF2905)
APOBLMKD_02650 1.6e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APOBLMKD_02651 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APOBLMKD_02652 2.5e-37 yajC U Preprotein translocase subunit YajC
APOBLMKD_02653 2.4e-60 yrzE S Protein of unknown function (DUF3792)
APOBLMKD_02654 9.5e-110 yrbG S membrane
APOBLMKD_02655 1.8e-271 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOBLMKD_02656 8.5e-50 yrzD S Post-transcriptional regulator
APOBLMKD_02657 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APOBLMKD_02658 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
APOBLMKD_02659 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
APOBLMKD_02660 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
APOBLMKD_02661 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APOBLMKD_02662 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APOBLMKD_02663 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APOBLMKD_02664 2.5e-273 lytH 3.5.1.28 M COG3103 SH3 domain protein
APOBLMKD_02667 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
APOBLMKD_02668 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
APOBLMKD_02669 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
APOBLMKD_02670 2.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
APOBLMKD_02671 7.8e-64 cymR K Transcriptional regulator
APOBLMKD_02672 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
APOBLMKD_02673 2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APOBLMKD_02674 1.7e-18 S COG0457 FOG TPR repeat
APOBLMKD_02675 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APOBLMKD_02676 3.4e-82 yrrD S protein conserved in bacteria
APOBLMKD_02677 2.9e-30 yrzR
APOBLMKD_02678 2.1e-08 S Protein of unknown function (DUF3918)
APOBLMKD_02679 4.9e-106 glnP P ABC transporter
APOBLMKD_02680 6.1e-109 gluC P ABC transporter
APOBLMKD_02681 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
APOBLMKD_02682 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APOBLMKD_02683 2e-162 yrrI S AI-2E family transporter
APOBLMKD_02684 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APOBLMKD_02685 8.5e-41 yrzL S Belongs to the UPF0297 family
APOBLMKD_02686 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APOBLMKD_02687 7.1e-46 yrzB S Belongs to the UPF0473 family
APOBLMKD_02688 2e-189 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APOBLMKD_02689 4.7e-117 yrrM 2.1.1.104 S O-methyltransferase
APOBLMKD_02690 2.9e-173 yegQ O Peptidase U32
APOBLMKD_02691 6.1e-246 yegQ O COG0826 Collagenase and related proteases
APOBLMKD_02692 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
APOBLMKD_02693 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APOBLMKD_02694 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
APOBLMKD_02695 8.1e-70 yrrS S Protein of unknown function (DUF1510)
APOBLMKD_02696 4.1e-27 yrzA S Protein of unknown function (DUF2536)
APOBLMKD_02697 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
APOBLMKD_02698 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APOBLMKD_02699 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
APOBLMKD_02700 1.2e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APOBLMKD_02701 5.1e-34 yrhC S YrhC-like protein
APOBLMKD_02702 7e-81 yrhD S Protein of unknown function (DUF1641)
APOBLMKD_02703 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
APOBLMKD_02704 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
APOBLMKD_02705 8e-143 focA P Formate nitrite
APOBLMKD_02707 7.1e-79 yrhH Q methyltransferase
APOBLMKD_02708 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
APOBLMKD_02709 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
APOBLMKD_02710 1.9e-212 ynfM EGP Major facilitator Superfamily
APOBLMKD_02711 4.1e-164 yybE K Transcriptional regulator
APOBLMKD_02712 2.6e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APOBLMKD_02713 8.7e-181 romA S Beta-lactamase superfamily domain
APOBLMKD_02714 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
APOBLMKD_02715 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
APOBLMKD_02716 3.8e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
APOBLMKD_02717 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
APOBLMKD_02718 3.9e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
APOBLMKD_02719 4.2e-144 S hydrolase
APOBLMKD_02721 8.9e-92 yrdA S DinB family
APOBLMKD_02722 1.5e-81 yyaR K Acetyltransferase (GNAT) domain
APOBLMKD_02723 1.5e-218 tetL EGP Major facilitator Superfamily
APOBLMKD_02725 9.2e-95 adk 2.7.4.3 F adenylate kinase activity
APOBLMKD_02726 3.4e-147 ydeE K AraC family transcriptional regulator
APOBLMKD_02727 2.1e-91 K Transcriptional regulator PadR-like family
APOBLMKD_02728 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
APOBLMKD_02729 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOBLMKD_02730 8.8e-213 EGP Major facilitator Superfamily
APOBLMKD_02731 8e-106 yqeD S SNARE associated Golgi protein
APOBLMKD_02732 3.8e-139 3.5.1.104 G Polysaccharide deacetylase
APOBLMKD_02733 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
APOBLMKD_02735 7.6e-94 yqeG S hydrolase of the HAD superfamily
APOBLMKD_02736 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
APOBLMKD_02737 1.2e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APOBLMKD_02738 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
APOBLMKD_02739 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APOBLMKD_02740 2.9e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
APOBLMKD_02741 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APOBLMKD_02742 1.1e-138 yqeM Q Methyltransferase
APOBLMKD_02743 3.8e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APOBLMKD_02744 9.6e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
APOBLMKD_02745 8e-105 comEB 3.5.4.12 F ComE operon protein 2
APOBLMKD_02746 0.0 comEC S Competence protein ComEC
APOBLMKD_02747 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
APOBLMKD_02748 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
APOBLMKD_02749 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
APOBLMKD_02750 7.8e-219 spoIIP M stage II sporulation protein P
APOBLMKD_02751 2.5e-53 yqxA S Protein of unknown function (DUF3679)
APOBLMKD_02752 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APOBLMKD_02753 8.5e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
APOBLMKD_02754 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APOBLMKD_02755 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APOBLMKD_02756 0.0 dnaK O Heat shock 70 kDa protein
APOBLMKD_02757 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APOBLMKD_02758 6.6e-173 prmA J Methylates ribosomal protein L11
APOBLMKD_02759 3.9e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APOBLMKD_02760 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
APOBLMKD_02761 3.3e-156 yqeW P COG1283 Na phosphate symporter
APOBLMKD_02762 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
APOBLMKD_02763 8e-68 yqeY S Yqey-like protein
APOBLMKD_02764 5.7e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
APOBLMKD_02765 3.8e-118 yqfA S UPF0365 protein
APOBLMKD_02766 9.9e-47 yqfB
APOBLMKD_02767 9.3e-46 yqfC S sporulation protein YqfC
APOBLMKD_02768 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
APOBLMKD_02769 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
APOBLMKD_02770 0.0 yqfF S membrane-associated HD superfamily hydrolase
APOBLMKD_02771 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APOBLMKD_02772 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
APOBLMKD_02773 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
APOBLMKD_02774 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APOBLMKD_02775 1.8e-16 S YqzL-like protein
APOBLMKD_02776 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
APOBLMKD_02777 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
APOBLMKD_02778 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
APOBLMKD_02779 4.5e-112 ccpN K CBS domain
APOBLMKD_02780 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
APOBLMKD_02781 6.1e-88 yaiI S Belongs to the UPF0178 family
APOBLMKD_02782 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APOBLMKD_02783 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APOBLMKD_02784 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
APOBLMKD_02785 1.4e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
APOBLMKD_02786 2.1e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APOBLMKD_02787 6.5e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
APOBLMKD_02788 3.7e-43 yqfQ S YqfQ-like protein
APOBLMKD_02789 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APOBLMKD_02790 4.8e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
APOBLMKD_02791 9.3e-37 yqfT S Protein of unknown function (DUF2624)
APOBLMKD_02792 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
APOBLMKD_02793 2.9e-72 zur P Belongs to the Fur family
APOBLMKD_02794 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
APOBLMKD_02795 2.3e-52 yqfX S membrane
APOBLMKD_02796 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
APOBLMKD_02797 3.1e-47 yqfZ M LysM domain
APOBLMKD_02798 2.4e-128 yqgB S Protein of unknown function (DUF1189)
APOBLMKD_02799 2.9e-71 yqgC S protein conserved in bacteria
APOBLMKD_02800 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
APOBLMKD_02801 3.4e-228 yqgE EGP Major facilitator superfamily
APOBLMKD_02802 0.0 pbpA 3.4.16.4 M penicillin-binding protein
APOBLMKD_02803 7.6e-158 pstS P Phosphate
APOBLMKD_02804 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
APOBLMKD_02805 2.9e-154 pstA P Phosphate transport system permease
APOBLMKD_02806 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APOBLMKD_02807 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APOBLMKD_02808 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APOBLMKD_02809 1.2e-50 yqzD
APOBLMKD_02810 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APOBLMKD_02811 3e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APOBLMKD_02812 4e-07 yqgO
APOBLMKD_02813 2.7e-231 nhaC C Na H antiporter
APOBLMKD_02814 8.5e-28 yqgQ S Protein conserved in bacteria
APOBLMKD_02815 2.2e-179 glcK 2.7.1.2 G Glucokinase
APOBLMKD_02816 2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
APOBLMKD_02817 1.1e-197 yqgU
APOBLMKD_02818 4.5e-49 yqgV S Thiamine-binding protein
APOBLMKD_02819 1.2e-19 yqgW S Protein of unknown function (DUF2759)
APOBLMKD_02820 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
APOBLMKD_02821 3.1e-37 yqgY S Protein of unknown function (DUF2626)
APOBLMKD_02822 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
APOBLMKD_02824 6.5e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APOBLMKD_02825 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
APOBLMKD_02826 1.2e-185 corA P Mg2 transporter protein
APOBLMKD_02827 5.6e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APOBLMKD_02828 2.4e-184 comGB NU COG1459 Type II secretory pathway, component PulF
APOBLMKD_02829 8.9e-50 comGC U Required for transformation and DNA binding
APOBLMKD_02830 2.2e-70 gspH NU Tfp pilus assembly protein FimT
APOBLMKD_02831 2.6e-20 comGE
APOBLMKD_02832 4.7e-25 comGF U Putative Competence protein ComGF
APOBLMKD_02833 2.8e-61 S ComG operon protein 7
APOBLMKD_02834 2.3e-26 yqzE S YqzE-like protein
APOBLMKD_02835 1.1e-53 yqzG S Protein of unknown function (DUF3889)
APOBLMKD_02836 3.6e-120 yqxM
APOBLMKD_02837 3.5e-71 sipW 3.4.21.89 U Signal peptidase
APOBLMKD_02838 1.6e-140 tasA S Cell division protein FtsN
APOBLMKD_02839 7.8e-55 sinR K transcriptional
APOBLMKD_02840 5.2e-23 sinI S Anti-repressor SinI
APOBLMKD_02841 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
APOBLMKD_02842 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
APOBLMKD_02843 2.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
APOBLMKD_02844 5.1e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APOBLMKD_02845 1.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APOBLMKD_02846 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
APOBLMKD_02847 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
APOBLMKD_02848 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
APOBLMKD_02849 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
APOBLMKD_02850 5.8e-62 yqhP
APOBLMKD_02851 8e-174 yqhQ S Protein of unknown function (DUF1385)
APOBLMKD_02852 3.7e-88 yqhR S Conserved membrane protein YqhR
APOBLMKD_02853 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
APOBLMKD_02854 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APOBLMKD_02855 1.8e-36 yqhV S Protein of unknown function (DUF2619)
APOBLMKD_02856 5.5e-172 spoIIIAA S stage III sporulation protein AA
APOBLMKD_02857 1.6e-83 spoIIIAB S Stage III sporulation protein
APOBLMKD_02858 7.6e-29 spoIIIAC S stage III sporulation protein AC
APOBLMKD_02859 2.5e-41 spoIIIAD S Stage III sporulation protein AD
APOBLMKD_02860 6.3e-200 spoIIIAE S stage III sporulation protein AE
APOBLMKD_02861 2.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
APOBLMKD_02862 1.1e-116 spoIIIAG S stage III sporulation protein AG
APOBLMKD_02863 2.5e-62 spoIIIAH S SpoIIIAH-like protein
APOBLMKD_02864 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APOBLMKD_02865 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
APOBLMKD_02866 8.1e-67 yqhY S protein conserved in bacteria
APOBLMKD_02867 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APOBLMKD_02868 2.5e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APOBLMKD_02869 1e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APOBLMKD_02870 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APOBLMKD_02871 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APOBLMKD_02872 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APOBLMKD_02873 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
APOBLMKD_02874 3.9e-78 argR K Regulates arginine biosynthesis genes
APOBLMKD_02875 7.9e-305 recN L May be involved in recombinational repair of damaged DNA
APOBLMKD_02876 6.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
APOBLMKD_02877 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
APOBLMKD_02878 2.6e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APOBLMKD_02881 4.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
APOBLMKD_02883 1.2e-112 K Protein of unknown function (DUF1232)
APOBLMKD_02884 7.7e-101 ytaF P Probably functions as a manganese efflux pump
APOBLMKD_02885 2.1e-16
APOBLMKD_02886 3.3e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
APOBLMKD_02887 2.8e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APOBLMKD_02888 8.3e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
APOBLMKD_02889 2.2e-154 hbdA 1.1.1.157 I Dehydrogenase
APOBLMKD_02890 2.2e-202 mmgC I acyl-CoA dehydrogenase
APOBLMKD_02891 7.2e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
APOBLMKD_02892 8.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
APOBLMKD_02893 2.4e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
APOBLMKD_02894 3.2e-34 yqzF S Protein of unknown function (DUF2627)
APOBLMKD_02895 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
APOBLMKD_02896 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
APOBLMKD_02897 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
APOBLMKD_02898 4.1e-206 buk 2.7.2.7 C Belongs to the acetokinase family
APOBLMKD_02899 1e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APOBLMKD_02900 2.1e-161 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APOBLMKD_02901 1e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APOBLMKD_02902 3.1e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APOBLMKD_02903 1.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APOBLMKD_02904 1e-75 yqiW S Belongs to the UPF0403 family
APOBLMKD_02905 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
APOBLMKD_02906 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
APOBLMKD_02907 3.8e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APOBLMKD_02908 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
APOBLMKD_02909 3.1e-95 yqjB S protein conserved in bacteria
APOBLMKD_02911 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
APOBLMKD_02912 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APOBLMKD_02913 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
APOBLMKD_02914 5e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APOBLMKD_02915 2.4e-25 yqzJ
APOBLMKD_02916 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APOBLMKD_02917 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APOBLMKD_02918 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APOBLMKD_02919 6.1e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APOBLMKD_02920 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APOBLMKD_02921 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
APOBLMKD_02922 5.5e-50 S GlpM protein
APOBLMKD_02923 1.4e-161 K LysR substrate binding domain
APOBLMKD_02924 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
APOBLMKD_02925 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APOBLMKD_02928 3.5e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APOBLMKD_02929 9.6e-127 IQ reductase
APOBLMKD_02931 8.4e-215 M Glycosyl transferase family 2
APOBLMKD_02932 2.7e-122 M PFAM Collagen triple helix repeat (20 copies)
APOBLMKD_02933 3e-215 hcaT 1.5.1.2 EGP Major facilitator Superfamily
APOBLMKD_02934 5.8e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
APOBLMKD_02935 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APOBLMKD_02936 5e-176 isp O Belongs to the peptidase S8 family
APOBLMKD_02937 5.6e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APOBLMKD_02938 2.1e-132 ykoC P Cobalt transport protein
APOBLMKD_02939 9.1e-303 P ABC transporter, ATP-binding protein
APOBLMKD_02940 1.3e-97 ykoE S ABC-type cobalt transport system, permease component
APOBLMKD_02941 7.4e-244 ydhD M Glycosyl hydrolase
APOBLMKD_02943 3.2e-237 mgtE P Acts as a magnesium transporter
APOBLMKD_02944 5.4e-53 tnrA K transcriptional
APOBLMKD_02945 1.9e-16
APOBLMKD_02946 3.1e-26 ykoL
APOBLMKD_02947 1.1e-80 ykoM K transcriptional
APOBLMKD_02948 6.4e-99 ykoP G polysaccharide deacetylase
APOBLMKD_02949 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
APOBLMKD_02950 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
APOBLMKD_02951 6.6e-99 ykoX S membrane-associated protein
APOBLMKD_02952 2.5e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
APOBLMKD_02953 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOBLMKD_02954 1.5e-118 rsgI S Anti-sigma factor N-terminus
APOBLMKD_02955 2.5e-26 sspD S small acid-soluble spore protein
APOBLMKD_02956 8.6e-125 ykrK S Domain of unknown function (DUF1836)
APOBLMKD_02957 4.5e-155 htpX O Belongs to the peptidase M48B family
APOBLMKD_02958 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
APOBLMKD_02959 7.2e-113 ydfR S Protein of unknown function (DUF421)
APOBLMKD_02960 8.7e-23 ykzE
APOBLMKD_02961 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
APOBLMKD_02962 0.0 kinE 2.7.13.3 T Histidine kinase
APOBLMKD_02963 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APOBLMKD_02965 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
APOBLMKD_02966 4.2e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
APOBLMKD_02967 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APOBLMKD_02968 1.6e-227 mtnE 2.6.1.83 E Aminotransferase
APOBLMKD_02969 5.1e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
APOBLMKD_02970 4.7e-128 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
APOBLMKD_02971 1.5e-112 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
APOBLMKD_02972 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
APOBLMKD_02973 3.4e-10 S Spo0E like sporulation regulatory protein
APOBLMKD_02974 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
APOBLMKD_02975 5.5e-77 ykvE K transcriptional
APOBLMKD_02976 2.7e-127 motB N Flagellar motor protein
APOBLMKD_02977 3.3e-136 motA N flagellar motor
APOBLMKD_02978 0.0 clpE O Belongs to the ClpA ClpB family
APOBLMKD_02979 1.3e-182 ykvI S membrane
APOBLMKD_02980 5e-183
APOBLMKD_02981 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
APOBLMKD_02982 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
APOBLMKD_02983 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
APOBLMKD_02984 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
APOBLMKD_02985 3.8e-44 ykvR S Protein of unknown function (DUF3219)
APOBLMKD_02986 7.8e-25 ykvS S protein conserved in bacteria
APOBLMKD_02987 3.9e-27
APOBLMKD_02988 6.9e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
APOBLMKD_02989 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOBLMKD_02990 1.7e-87 stoA CO thiol-disulfide
APOBLMKD_02991 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
APOBLMKD_02992 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
APOBLMKD_02994 7.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
APOBLMKD_02995 5.1e-156 glcT K antiterminator
APOBLMKD_02996 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOBLMKD_02997 2.1e-39 ptsH G phosphocarrier protein HPr
APOBLMKD_02998 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APOBLMKD_02999 6.1e-38 splA S Transcriptional regulator
APOBLMKD_03000 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
APOBLMKD_03001 2.4e-257 mcpC NT chemotaxis protein
APOBLMKD_03002 2.1e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
APOBLMKD_03003 1.5e-114 ykwD J protein with SCP PR1 domains
APOBLMKD_03004 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
APOBLMKD_03005 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
APOBLMKD_03006 3.9e-215 patA 2.6.1.1 E Aminotransferase
APOBLMKD_03007 2.3e-09
APOBLMKD_03008 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
APOBLMKD_03009 1.4e-83 ykyB S YkyB-like protein
APOBLMKD_03010 6.6e-240 ykuC EGP Major facilitator Superfamily
APOBLMKD_03011 1.6e-88 ykuD S protein conserved in bacteria
APOBLMKD_03012 2e-152 ykuE S Metallophosphoesterase
APOBLMKD_03013 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_03015 3.3e-233 ykuI T Diguanylate phosphodiesterase
APOBLMKD_03016 3.9e-37 ykuJ S protein conserved in bacteria
APOBLMKD_03017 9.2e-92 ykuK S Ribonuclease H-like
APOBLMKD_03018 2.1e-25 ykzF S Antirepressor AbbA
APOBLMKD_03019 1e-75 ykuL S CBS domain
APOBLMKD_03020 1.3e-167 ccpC K Transcriptional regulator
APOBLMKD_03021 1.3e-89 fld C Flavodoxin
APOBLMKD_03022 1.7e-165 ykuO
APOBLMKD_03023 6e-79 fld C Flavodoxin
APOBLMKD_03024 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APOBLMKD_03025 9.9e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APOBLMKD_03026 4.8e-38 ykuS S Belongs to the UPF0180 family
APOBLMKD_03027 3.7e-140 ykuT M Mechanosensitive ion channel
APOBLMKD_03028 2.2e-76 ykuV CO thiol-disulfide
APOBLMKD_03029 4.5e-98 rok K Repressor of ComK
APOBLMKD_03030 1.1e-160 yknT
APOBLMKD_03031 2.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
APOBLMKD_03032 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APOBLMKD_03033 1.7e-243 moeA 2.10.1.1 H molybdopterin
APOBLMKD_03034 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
APOBLMKD_03035 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
APOBLMKD_03036 5.7e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
APOBLMKD_03037 7.5e-105 yknW S Yip1 domain
APOBLMKD_03038 6e-168 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APOBLMKD_03039 2e-121 macB V ABC transporter, ATP-binding protein
APOBLMKD_03040 3e-210 yknZ V ABC transporter (permease)
APOBLMKD_03041 1.7e-131 fruR K Transcriptional regulator
APOBLMKD_03042 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
APOBLMKD_03043 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
APOBLMKD_03044 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
APOBLMKD_03045 1.7e-36 ykoA
APOBLMKD_03046 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APOBLMKD_03047 1.7e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APOBLMKD_03048 3.6e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
APOBLMKD_03049 5.5e-12 S Uncharacterized protein YkpC
APOBLMKD_03050 6.9e-184 mreB D Rod-share determining protein MreBH
APOBLMKD_03051 1.8e-44 abrB K of stationary sporulation gene expression
APOBLMKD_03052 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
APOBLMKD_03053 1.9e-147 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
APOBLMKD_03054 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
APOBLMKD_03055 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
APOBLMKD_03056 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APOBLMKD_03057 8.2e-31 ykzG S Belongs to the UPF0356 family
APOBLMKD_03058 7.4e-146 ykrA S hydrolases of the HAD superfamily
APOBLMKD_03059 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APOBLMKD_03061 1.6e-101 recN L Putative cell-wall binding lipoprotein
APOBLMKD_03062 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APOBLMKD_03063 0.0 Q Polyketide synthase of type I
APOBLMKD_03064 0.0 Q polyketide synthase
APOBLMKD_03065 0.0 Q Polyketide synthase of type I
APOBLMKD_03066 0.0 Q Polyketide synthase of type I
APOBLMKD_03067 0.0 Q Polyketide synthase of type I
APOBLMKD_03068 0.0 Q Polyketide synthase of type I
APOBLMKD_03069 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
APOBLMKD_03070 3.3e-208 V Beta-lactamase
APOBLMKD_03071 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APOBLMKD_03072 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APOBLMKD_03073 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APOBLMKD_03074 5.4e-251 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APOBLMKD_03075 1.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
APOBLMKD_03076 4.6e-135 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
APOBLMKD_03077 3.2e-275 speA 4.1.1.19 E Arginine
APOBLMKD_03078 1.6e-42 yktA S Belongs to the UPF0223 family
APOBLMKD_03079 1.8e-118 yktB S Belongs to the UPF0637 family
APOBLMKD_03080 6.3e-24 ykzI
APOBLMKD_03081 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
APOBLMKD_03082 4e-83 ykzC S Acetyltransferase (GNAT) family
APOBLMKD_03083 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
APOBLMKD_03084 2.2e-13 sigC S Putative zinc-finger
APOBLMKD_03085 2.3e-36 ylaE
APOBLMKD_03086 6.7e-24 S Family of unknown function (DUF5325)
APOBLMKD_03087 0.0 typA T GTP-binding protein TypA
APOBLMKD_03088 6.6e-48 ylaH S YlaH-like protein
APOBLMKD_03089 1.4e-33 ylaI S protein conserved in bacteria
APOBLMKD_03090 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APOBLMKD_03091 8.6e-243 phoH T ATPase related to phosphate starvation-inducible protein PhoH
APOBLMKD_03092 9.4e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
APOBLMKD_03093 3.9e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
APOBLMKD_03094 8.7e-44 ylaN S Belongs to the UPF0358 family
APOBLMKD_03095 1.9e-212 ftsW D Belongs to the SEDS family
APOBLMKD_03096 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APOBLMKD_03097 1.7e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
APOBLMKD_03098 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APOBLMKD_03099 1.2e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
APOBLMKD_03100 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APOBLMKD_03101 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
APOBLMKD_03102 1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
APOBLMKD_03103 2e-163 ctaG S cytochrome c oxidase
APOBLMKD_03104 3.2e-59 ylbA S YugN-like family
APOBLMKD_03105 2.2e-73 ylbB T COG0517 FOG CBS domain
APOBLMKD_03106 6.6e-198 ylbC S protein with SCP PR1 domains
APOBLMKD_03107 2.1e-54 ylbD S Putative coat protein
APOBLMKD_03108 8.8e-37 ylbE S YlbE-like protein
APOBLMKD_03109 1.2e-71 ylbF S Belongs to the UPF0342 family
APOBLMKD_03110 5.5e-43 ylbG S UPF0298 protein
APOBLMKD_03112 2.7e-97 rsmD 2.1.1.171 L Methyltransferase
APOBLMKD_03113 9.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APOBLMKD_03114 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
APOBLMKD_03115 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
APOBLMKD_03116 1.6e-188 ylbL T Belongs to the peptidase S16 family
APOBLMKD_03117 1.3e-227 ylbM S Belongs to the UPF0348 family
APOBLMKD_03118 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
APOBLMKD_03119 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
APOBLMKD_03120 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
APOBLMKD_03121 1.2e-88 ylbP K n-acetyltransferase
APOBLMKD_03122 9.4e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APOBLMKD_03123 2.5e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
APOBLMKD_03124 1.2e-77 mraZ K Belongs to the MraZ family
APOBLMKD_03125 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APOBLMKD_03126 2.9e-52 ftsL D Essential cell division protein
APOBLMKD_03127 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
APOBLMKD_03128 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
APOBLMKD_03129 2.6e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APOBLMKD_03130 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APOBLMKD_03131 6.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APOBLMKD_03132 2.2e-185 spoVE D Belongs to the SEDS family
APOBLMKD_03133 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APOBLMKD_03134 1.8e-167 murB 1.3.1.98 M cell wall formation
APOBLMKD_03135 2.4e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APOBLMKD_03136 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APOBLMKD_03137 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APOBLMKD_03138 0.0 bpr O COG1404 Subtilisin-like serine proteases
APOBLMKD_03139 4.1e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
APOBLMKD_03140 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOBLMKD_03141 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOBLMKD_03142 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
APOBLMKD_03143 5.1e-249 argE 3.5.1.16 E Acetylornithine deacetylase
APOBLMKD_03144 2.2e-38 ylmC S sporulation protein
APOBLMKD_03145 4.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
APOBLMKD_03146 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APOBLMKD_03147 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APOBLMKD_03148 5.2e-41 yggT S membrane
APOBLMKD_03149 1.4e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
APOBLMKD_03150 8.9e-68 divIVA D Cell division initiation protein
APOBLMKD_03151 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APOBLMKD_03152 1.2e-61 dksA T COG1734 DnaK suppressor protein
APOBLMKD_03153 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APOBLMKD_03154 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APOBLMKD_03155 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APOBLMKD_03156 8.8e-232 pyrP F Xanthine uracil
APOBLMKD_03157 2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
APOBLMKD_03158 1.2e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APOBLMKD_03159 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APOBLMKD_03160 0.0 carB 6.3.5.5 F Belongs to the CarB family
APOBLMKD_03161 5e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
APOBLMKD_03162 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APOBLMKD_03163 6.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APOBLMKD_03164 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APOBLMKD_03165 1.1e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
APOBLMKD_03166 1.1e-176 cysP P phosphate transporter
APOBLMKD_03167 2.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
APOBLMKD_03168 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
APOBLMKD_03169 3.8e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
APOBLMKD_03170 5.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
APOBLMKD_03171 4.6e-77 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
APOBLMKD_03172 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
APOBLMKD_03173 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
APOBLMKD_03174 8.5e-154 yloC S stress-induced protein
APOBLMKD_03175 1.5e-40 ylzA S Belongs to the UPF0296 family
APOBLMKD_03176 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
APOBLMKD_03177 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APOBLMKD_03178 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APOBLMKD_03179 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APOBLMKD_03180 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APOBLMKD_03181 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APOBLMKD_03182 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APOBLMKD_03183 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APOBLMKD_03184 6.6e-139 stp 3.1.3.16 T phosphatase
APOBLMKD_03185 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
APOBLMKD_03186 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APOBLMKD_03187 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
APOBLMKD_03188 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
APOBLMKD_03189 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
APOBLMKD_03190 5.5e-59 asp S protein conserved in bacteria
APOBLMKD_03191 1.4e-303 yloV S kinase related to dihydroxyacetone kinase
APOBLMKD_03192 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
APOBLMKD_03193 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
APOBLMKD_03194 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APOBLMKD_03195 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
APOBLMKD_03196 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APOBLMKD_03197 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APOBLMKD_03198 4.6e-129 IQ reductase
APOBLMKD_03199 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APOBLMKD_03200 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APOBLMKD_03201 0.0 smc D Required for chromosome condensation and partitioning
APOBLMKD_03202 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APOBLMKD_03203 1.4e-139 S Phosphotransferase enzyme family
APOBLMKD_03204 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APOBLMKD_03205 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APOBLMKD_03206 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
APOBLMKD_03207 6.4e-35 ylqC S Belongs to the UPF0109 family
APOBLMKD_03208 1.3e-61 ylqD S YlqD protein
APOBLMKD_03209 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APOBLMKD_03210 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
APOBLMKD_03211 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APOBLMKD_03212 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APOBLMKD_03213 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APOBLMKD_03214 1e-301 ylqG
APOBLMKD_03215 2.5e-43 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
APOBLMKD_03216 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
APOBLMKD_03217 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APOBLMKD_03218 1.2e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
APOBLMKD_03219 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APOBLMKD_03220 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APOBLMKD_03221 1.6e-171 xerC L tyrosine recombinase XerC
APOBLMKD_03222 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
APOBLMKD_03223 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
APOBLMKD_03224 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
APOBLMKD_03225 2e-54 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
APOBLMKD_03226 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
APOBLMKD_03227 2.5e-31 fliE N Flagellar hook-basal body
APOBLMKD_03228 1.4e-263 fliF N The M ring may be actively involved in energy transduction
APOBLMKD_03229 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APOBLMKD_03230 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
APOBLMKD_03231 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
APOBLMKD_03232 2e-71 fliJ N Flagellar biosynthesis chaperone
APOBLMKD_03233 4.8e-47 ylxF S MgtE intracellular N domain
APOBLMKD_03234 2.3e-203 fliK N Flagellar hook-length control protein
APOBLMKD_03235 4.1e-72 flgD N Flagellar basal body rod modification protein
APOBLMKD_03236 5.7e-138 flgG N Flagellar basal body rod
APOBLMKD_03237 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
APOBLMKD_03238 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APOBLMKD_03239 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
APOBLMKD_03240 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
APOBLMKD_03241 1.9e-110 fliZ N Flagellar biosynthesis protein, FliO
APOBLMKD_03242 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
APOBLMKD_03243 2e-37 fliQ N Role in flagellar biosynthesis
APOBLMKD_03244 5.2e-131 fliR N Flagellar biosynthetic protein FliR
APOBLMKD_03245 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APOBLMKD_03246 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APOBLMKD_03247 2.2e-191 flhF N Flagellar biosynthesis regulator FlhF
APOBLMKD_03248 2.4e-156 flhG D Belongs to the ParA family
APOBLMKD_03249 1.2e-191 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
APOBLMKD_03250 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
APOBLMKD_03251 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
APOBLMKD_03252 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
APOBLMKD_03253 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
APOBLMKD_03254 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOBLMKD_03255 8e-50 ylxL
APOBLMKD_03256 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
APOBLMKD_03257 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APOBLMKD_03258 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
APOBLMKD_03259 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APOBLMKD_03260 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APOBLMKD_03261 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
APOBLMKD_03262 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
APOBLMKD_03263 5.9e-233 rasP M zinc metalloprotease
APOBLMKD_03264 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APOBLMKD_03265 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APOBLMKD_03266 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
APOBLMKD_03267 5.4e-206 nusA K Participates in both transcription termination and antitermination
APOBLMKD_03268 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
APOBLMKD_03269 1.8e-47 ylxQ J ribosomal protein
APOBLMKD_03270 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APOBLMKD_03271 3.9e-44 ylxP S protein conserved in bacteria
APOBLMKD_03272 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APOBLMKD_03273 4.7e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APOBLMKD_03274 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
APOBLMKD_03275 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APOBLMKD_03276 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
APOBLMKD_03277 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
APOBLMKD_03278 1.2e-233 pepR S Belongs to the peptidase M16 family
APOBLMKD_03279 2.6e-42 ymxH S YlmC YmxH family
APOBLMKD_03280 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
APOBLMKD_03281 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
APOBLMKD_03282 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APOBLMKD_03283 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
APOBLMKD_03284 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APOBLMKD_03285 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APOBLMKD_03286 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
APOBLMKD_03287 6.3e-31 S YlzJ-like protein
APOBLMKD_03288 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
APOBLMKD_03289 1.2e-132 ymfC K Transcriptional regulator
APOBLMKD_03290 3e-227 ymfD EGP Major facilitator Superfamily
APOBLMKD_03291 2.4e-75 K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_03292 0.0 ydgH S drug exporters of the RND superfamily
APOBLMKD_03293 6.8e-237 ymfF S Peptidase M16
APOBLMKD_03294 3.5e-241 ymfH S zinc protease
APOBLMKD_03295 6.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
APOBLMKD_03296 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
APOBLMKD_03297 1e-142 ymfK S Protein of unknown function (DUF3388)
APOBLMKD_03298 1.9e-124 ymfM S protein conserved in bacteria
APOBLMKD_03299 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APOBLMKD_03300 1.2e-230 cinA 3.5.1.42 S Belongs to the CinA family
APOBLMKD_03301 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APOBLMKD_03302 1.1e-193 pbpX V Beta-lactamase
APOBLMKD_03303 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
APOBLMKD_03304 4.9e-153 ymdB S protein conserved in bacteria
APOBLMKD_03305 1.2e-36 spoVS S Stage V sporulation protein S
APOBLMKD_03306 2.4e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
APOBLMKD_03307 2.6e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APOBLMKD_03308 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
APOBLMKD_03309 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
APOBLMKD_03310 1.7e-88 cotE S Spore coat protein
APOBLMKD_03311 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APOBLMKD_03312 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APOBLMKD_03313 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
APOBLMKD_03314 5.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APOBLMKD_03315 1.6e-182 pksD Q Acyl transferase domain
APOBLMKD_03316 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APOBLMKD_03317 5.5e-34 acpK IQ Phosphopantetheine attachment site
APOBLMKD_03318 2.4e-242 pksG 2.3.3.10 I synthase
APOBLMKD_03319 9.1e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
APOBLMKD_03320 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
APOBLMKD_03321 0.0 rhiB IQ polyketide synthase
APOBLMKD_03322 0.0 Q Polyketide synthase of type I
APOBLMKD_03323 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
APOBLMKD_03324 0.0 dhbF IQ polyketide synthase
APOBLMKD_03325 0.0 pks13 HQ Beta-ketoacyl synthase
APOBLMKD_03326 8.4e-229 cypA C Cytochrome P450
APOBLMKD_03327 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
APOBLMKD_03328 3.6e-118 yoaK S Membrane
APOBLMKD_03329 4.1e-62 ymzB
APOBLMKD_03330 2.9e-254 aprX O Belongs to the peptidase S8 family
APOBLMKD_03332 3e-125 ymaC S Replication protein
APOBLMKD_03333 1.7e-78 ymaD O redox protein, regulator of disulfide bond formation
APOBLMKD_03334 2.6e-53 ebrB P Small Multidrug Resistance protein
APOBLMKD_03335 2.6e-47 ebrA P Small Multidrug Resistance protein
APOBLMKD_03337 9.2e-47 ymaF S YmaF family
APOBLMKD_03338 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APOBLMKD_03339 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
APOBLMKD_03340 1.2e-42
APOBLMKD_03341 1.8e-20 ymzA
APOBLMKD_03342 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
APOBLMKD_03343 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APOBLMKD_03344 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APOBLMKD_03345 7.6e-109 ymaB S MutT family
APOBLMKD_03346 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOBLMKD_03347 1.3e-176 spoVK O stage V sporulation protein K
APOBLMKD_03348 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APOBLMKD_03349 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
APOBLMKD_03350 4.3e-68 glnR K transcriptional
APOBLMKD_03351 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
APOBLMKD_03352 3.3e-208 mrjp G Major royal jelly protein
APOBLMKD_03353 1.9e-248 xynT G MFS/sugar transport protein
APOBLMKD_03354 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
APOBLMKD_03355 2.7e-208 xylR GK ROK family
APOBLMKD_03356 4.1e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
APOBLMKD_03357 1.3e-284 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
APOBLMKD_03358 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
APOBLMKD_03362 3.7e-185 adhP 1.1.1.1 C alcohol dehydrogenase
APOBLMKD_03364 3.8e-63 yoaP 3.1.3.18 K YoaP-like
APOBLMKD_03365 4.2e-59 yoaP 3.1.3.18 K YoaP-like
APOBLMKD_03366 1.6e-99 J Acetyltransferase (GNAT) domain
APOBLMKD_03367 6.6e-116 ynaE S Domain of unknown function (DUF3885)
APOBLMKD_03368 1.1e-200 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOBLMKD_03369 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
APOBLMKD_03372 5.6e-92 yvgO
APOBLMKD_03374 0.0 yobO M Pectate lyase superfamily protein
APOBLMKD_03375 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
APOBLMKD_03376 2.6e-141 yndL S Replication protein
APOBLMKD_03377 9.1e-08
APOBLMKD_03378 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
APOBLMKD_03379 1.2e-71 yndM S Protein of unknown function (DUF2512)
APOBLMKD_03380 2.1e-12 yoaW
APOBLMKD_03381 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APOBLMKD_03382 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
APOBLMKD_03383 3.5e-112 yneB L resolvase
APOBLMKD_03384 9.8e-33 ynzC S UPF0291 protein
APOBLMKD_03385 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APOBLMKD_03386 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
APOBLMKD_03387 2.3e-28 yneF S UPF0154 protein
APOBLMKD_03388 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
APOBLMKD_03389 1.7e-125 ccdA O cytochrome c biogenesis protein
APOBLMKD_03390 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
APOBLMKD_03391 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
APOBLMKD_03392 2.5e-74 yneK S Protein of unknown function (DUF2621)
APOBLMKD_03393 1.1e-62 hspX O Spore coat protein
APOBLMKD_03394 2.3e-19 sspP S Belongs to the SspP family
APOBLMKD_03395 7.5e-15 sspO S Belongs to the SspO family
APOBLMKD_03396 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
APOBLMKD_03397 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APOBLMKD_03400 7.1e-18 tlp S Belongs to the Tlp family
APOBLMKD_03401 8.3e-75 yneP S Thioesterase-like superfamily
APOBLMKD_03402 1.4e-52 yneQ
APOBLMKD_03403 1.1e-49 yneR S Belongs to the HesB IscA family
APOBLMKD_03404 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APOBLMKD_03405 1.5e-68 yccU S CoA-binding protein
APOBLMKD_03406 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APOBLMKD_03407 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APOBLMKD_03408 6e-13
APOBLMKD_03409 5.1e-41 ynfC
APOBLMKD_03410 5.2e-246 agcS E Sodium alanine symporter
APOBLMKD_03411 1.3e-179 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
APOBLMKD_03412 3.4e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
APOBLMKD_03413 3.4e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
APOBLMKD_03414 9.2e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
APOBLMKD_03415 2.3e-145 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOBLMKD_03416 3.9e-179 kdgR_1 K transcriptional
APOBLMKD_03417 1.3e-219 exuT G Sugar (and other) transporter
APOBLMKD_03418 5.4e-155 yndG S DoxX-like family
APOBLMKD_03419 9.5e-80 yndH S Domain of unknown function (DUF4166)
APOBLMKD_03420 4.1e-295 yndJ S YndJ-like protein
APOBLMKD_03421 5.7e-25 S Platelet-activating factor acetylhydrolase, isoform II
APOBLMKD_03422 4.6e-285 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
APOBLMKD_03423 6.9e-50 S Domain of unknown function (DUF4870)
APOBLMKD_03424 1.3e-228 T PhoQ Sensor
APOBLMKD_03425 1.2e-126 T Transcriptional regulatory protein, C terminal
APOBLMKD_03426 7.4e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
APOBLMKD_03427 1.2e-291 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
APOBLMKD_03428 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_03429 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_03430 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_03431 2.8e-216 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APOBLMKD_03432 6.4e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
APOBLMKD_03433 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APOBLMKD_03434 3.8e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APOBLMKD_03435 1.4e-251 yxjC EG COG2610 H gluconate symporter and related permeases
APOBLMKD_03436 5.6e-217 bioI 1.14.14.46 C Cytochrome P450
APOBLMKD_03437 1.2e-191 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
APOBLMKD_03438 4.1e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
APOBLMKD_03439 1.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APOBLMKD_03440 3.3e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
APOBLMKD_03441 3.1e-144 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
APOBLMKD_03442 9.6e-68 yngA S membrane
APOBLMKD_03443 8.9e-159 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APOBLMKD_03444 3.2e-104 yngC S SNARE associated Golgi protein
APOBLMKD_03445 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APOBLMKD_03446 3.7e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
APOBLMKD_03447 1.2e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
APOBLMKD_03448 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
APOBLMKD_03449 7.9e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
APOBLMKD_03450 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APOBLMKD_03451 3.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
APOBLMKD_03452 7.3e-302 yngK T Glycosyl hydrolase-like 10
APOBLMKD_03453 1.2e-64 yngL S Protein of unknown function (DUF1360)
APOBLMKD_03454 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
APOBLMKD_03455 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_03458 1.1e-248 iolT EGP Major facilitator Superfamily
APOBLMKD_03459 7.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
APOBLMKD_03460 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
APOBLMKD_03461 1.9e-163 ydhU P Catalase
APOBLMKD_03462 2.1e-296 yveA E amino acid
APOBLMKD_03463 2.9e-102 yvdT K Transcriptional regulator
APOBLMKD_03464 2.3e-51 ykkC P Small Multidrug Resistance protein
APOBLMKD_03465 7.7e-49 sugE P Small Multidrug Resistance protein
APOBLMKD_03466 8.2e-216 yeaN P COG2807 Cyanate permease
APOBLMKD_03467 9.9e-118 K FCD
APOBLMKD_03468 1.5e-132 ydhQ K UTRA
APOBLMKD_03469 2e-195 pbuE EGP Major facilitator Superfamily
APOBLMKD_03470 5.5e-98 ydhK M Protein of unknown function (DUF1541)
APOBLMKD_03472 5.5e-261 pbpE V Beta-lactamase
APOBLMKD_03475 3.5e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APOBLMKD_03476 2.4e-119 ydhC K FCD
APOBLMKD_03477 1.6e-33 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
APOBLMKD_03480 1e-81 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
APOBLMKD_03481 7e-144 ycgJ_1 Q ubiE/COQ5 methyltransferase family
APOBLMKD_03482 1.9e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
APOBLMKD_03483 2.4e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APOBLMKD_03484 7.6e-149 bltR K helix_turn_helix, mercury resistance
APOBLMKD_03485 2.2e-81 bltD 2.3.1.57 K FR47-like protein
APOBLMKD_03486 9.4e-122 ydhB S membrane transporter protein
APOBLMKD_03487 1.9e-155 K Helix-turn-helix XRE-family like proteins
APOBLMKD_03488 1.1e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APOBLMKD_03489 3.9e-210 tcaB EGP Major facilitator Superfamily
APOBLMKD_03490 2.7e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
APOBLMKD_03491 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
APOBLMKD_03492 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
APOBLMKD_03493 3.9e-298 expZ S ABC transporter
APOBLMKD_03494 1.8e-133 puuD S Peptidase C26
APOBLMKD_03495 0.0 ydfJ S drug exporters of the RND superfamily
APOBLMKD_03496 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOBLMKD_03497 4.3e-215 ydfH 2.7.13.3 T Histidine kinase
APOBLMKD_03498 1.3e-35 yraG
APOBLMKD_03499 8.4e-63 yraF M Spore coat protein
APOBLMKD_03500 9.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APOBLMKD_03501 3.1e-24 yraE
APOBLMKD_03502 1.4e-47 yraD M Spore coat protein
APOBLMKD_03503 1.9e-17 ydeS K Transcriptional regulator
APOBLMKD_03504 1.2e-100 ydeS K Transcriptional regulator
APOBLMKD_03505 1.1e-177 ydeR EGP Major facilitator Superfamily
APOBLMKD_03507 3.5e-114 paiB K Transcriptional regulator
APOBLMKD_03508 5.8e-258 K helix_turn_helix gluconate operon transcriptional repressor
APOBLMKD_03509 2.3e-224 mleN_2 C antiporter
APOBLMKD_03510 3.6e-67 yraB K helix_turn_helix, mercury resistance
APOBLMKD_03511 1.1e-200 adhA 1.1.1.1 C alcohol dehydrogenase
APOBLMKD_03512 2e-164 S Sodium Bile acid symporter family
APOBLMKD_03513 2.2e-50 ydeH
APOBLMKD_03514 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
APOBLMKD_03516 3.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
APOBLMKD_03517 1.8e-14 ykkA S Protein of unknown function (DUF664)
APOBLMKD_03520 2.6e-194 trkA P Oxidoreductase
APOBLMKD_03521 8.4e-168 czcD P COG1230 Co Zn Cd efflux system component
APOBLMKD_03522 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOBLMKD_03523 6.6e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
APOBLMKD_03526 5.1e-44 G Cupin domain
APOBLMKD_03527 1.3e-30 S DinB superfamily
APOBLMKD_03528 2.3e-181 S Patatin-like phospholipase
APOBLMKD_03529 2.4e-50 K Transcriptional regulator PadR-like family
APOBLMKD_03530 4.1e-101 S Protein of unknown function (DUF2812)
APOBLMKD_03531 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
APOBLMKD_03532 7.3e-117 yrkJ S membrane transporter protein
APOBLMKD_03533 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
APOBLMKD_03534 1.2e-200 yrkH P Rhodanese Homology Domain
APOBLMKD_03535 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
APOBLMKD_03536 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
APOBLMKD_03537 9.2e-40 yrkD S protein conserved in bacteria
APOBLMKD_03538 1.4e-30 cspL K Cold shock
APOBLMKD_03539 4.2e-110 ywnB S NAD(P)H-binding
APOBLMKD_03540 2.6e-71 ywnA K Transcriptional regulator
APOBLMKD_03541 1.4e-48 ohrR K Transcriptional regulator
APOBLMKD_03542 1.3e-46 ohrB O OsmC-like protein
APOBLMKD_03543 3.8e-136 I esterase
APOBLMKD_03544 3.5e-234 proP EGP Transporter
APOBLMKD_03545 2e-149 S Serine aminopeptidase, S33
APOBLMKD_03546 1.1e-95 ywrO S Flavodoxin-like fold
APOBLMKD_03554 8.6e-59 ydcK S Belongs to the SprT family
APOBLMKD_03555 1.7e-14
APOBLMKD_03556 0.0 yhgF K COG2183 Transcriptional accessory protein
APOBLMKD_03557 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
APOBLMKD_03558 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOBLMKD_03559 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
APOBLMKD_03560 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
APOBLMKD_03561 1.7e-187 rsbU 3.1.3.3 KT phosphatase
APOBLMKD_03562 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
APOBLMKD_03563 1.8e-57 rsbS T antagonist
APOBLMKD_03564 2.3e-145 rsbR T Positive regulator of sigma-B
APOBLMKD_03565 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
APOBLMKD_03566 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
APOBLMKD_03567 2.6e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APOBLMKD_03568 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
APOBLMKD_03569 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APOBLMKD_03570 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
APOBLMKD_03571 3.5e-261 ydbT S Membrane
APOBLMKD_03572 1.8e-81 ydbS S Bacterial PH domain
APOBLMKD_03573 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APOBLMKD_03574 2.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APOBLMKD_03575 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
APOBLMKD_03576 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APOBLMKD_03577 8.1e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APOBLMKD_03578 5.8e-09 S Fur-regulated basic protein A
APOBLMKD_03579 4.3e-10 S Fur-regulated basic protein B
APOBLMKD_03580 7.3e-206 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
APOBLMKD_03581 4.6e-52 ydbL
APOBLMKD_03582 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APOBLMKD_03583 2.3e-170 ydbJ V ABC transporter, ATP-binding protein
APOBLMKD_03584 4e-158 ydbI S AI-2E family transporter
APOBLMKD_03585 2.9e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOBLMKD_03586 9.7e-118 dctR T COG4565 Response regulator of citrate malate metabolism
APOBLMKD_03587 2.1e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APOBLMKD_03588 5.5e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
APOBLMKD_03589 1.2e-154 ydbD P Catalase
APOBLMKD_03590 3.8e-60 ydbC S Domain of unknown function (DUF4937
APOBLMKD_03591 3.4e-58 ydbB G Cupin domain
APOBLMKD_03592 0.0 srfAC Q TIGRFAM amino acid adenylation domain
APOBLMKD_03593 8.7e-120 fabD 2.3.1.39 I PFAM Acyl transferase
APOBLMKD_03594 0.0 Q Beta-ketoacyl synthase
APOBLMKD_03595 0.0 Q Polyketide synthase modules and related proteins
APOBLMKD_03596 1.2e-102 Q Flavin containing amine oxidoreductase
APOBLMKD_03597 0.0 Q TIGRFAM amino acid adenylation domain
APOBLMKD_03598 5.1e-49 crtF 2.1.1.210 Q PFAM O-methyltransferase
APOBLMKD_03599 8.5e-76 S Domain of unknown function (DUF4879)
APOBLMKD_03600 7.5e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
APOBLMKD_03601 2.1e-107 yqeB
APOBLMKD_03602 9.2e-40 ybyB
APOBLMKD_03603 2.8e-291 ybeC E amino acid
APOBLMKD_03604 1.1e-55
APOBLMKD_03605 1.8e-16 S Protein of unknown function (DUF2651)
APOBLMKD_03606 9.7e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APOBLMKD_03607 1.7e-259 glpT G -transporter
APOBLMKD_03608 1e-16 S Protein of unknown function (DUF2651)
APOBLMKD_03609 4.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
APOBLMKD_03611 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
APOBLMKD_03612 2e-31
APOBLMKD_03613 1.2e-82 K Helix-turn-helix XRE-family like proteins
APOBLMKD_03614 8.3e-196 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
APOBLMKD_03615 1.5e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
APOBLMKD_03616 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APOBLMKD_03617 2.1e-85 ybfM S SNARE associated Golgi protein
APOBLMKD_03618 2.5e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
APOBLMKD_03619 6.1e-42 ybfN
APOBLMKD_03620 5e-192 yceA S Belongs to the UPF0176 family
APOBLMKD_03621 9.3e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOBLMKD_03622 1.9e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
APOBLMKD_03623 5.2e-257 mmuP E amino acid
APOBLMKD_03624 2.3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
APOBLMKD_03625 2.7e-258 agcS E Sodium alanine symporter
APOBLMKD_03626 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
APOBLMKD_03627 2.4e-205 phoQ 2.7.13.3 T Histidine kinase
APOBLMKD_03628 8.2e-171 glnL T Regulator
APOBLMKD_03629 1.3e-125 ycbJ S Macrolide 2'-phosphotransferase
APOBLMKD_03630 1.8e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
APOBLMKD_03631 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APOBLMKD_03632 4.5e-109 ydfN C nitroreductase
APOBLMKD_03633 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
APOBLMKD_03634 1.5e-62 mhqP S DoxX
APOBLMKD_03635 9.1e-56 traF CO Thioredoxin
APOBLMKD_03636 5.6e-62 ycbP S Protein of unknown function (DUF2512)
APOBLMKD_03637 5.3e-77 sleB 3.5.1.28 M Cell wall
APOBLMKD_03638 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
APOBLMKD_03639 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APOBLMKD_03640 1.3e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APOBLMKD_03641 3.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APOBLMKD_03642 4.6e-205 ycbU E Selenocysteine lyase
APOBLMKD_03643 1e-241 lmrB EGP the major facilitator superfamily
APOBLMKD_03644 6.5e-99 yxaF K Transcriptional regulator
APOBLMKD_03645 2.5e-195 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
APOBLMKD_03646 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
APOBLMKD_03647 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
APOBLMKD_03648 6.2e-171 yccK C Aldo keto reductase
APOBLMKD_03649 1.5e-175 ycdA S Domain of unknown function (DUF5105)
APOBLMKD_03650 1.9e-253 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
APOBLMKD_03651 5.7e-266 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
APOBLMKD_03652 5.8e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
APOBLMKD_03653 1e-188 S response regulator aspartate phosphatase
APOBLMKD_03654 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
APOBLMKD_03655 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
APOBLMKD_03656 2.2e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
APOBLMKD_03657 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APOBLMKD_03658 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APOBLMKD_03659 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOBLMKD_03660 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
APOBLMKD_03661 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
APOBLMKD_03662 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
APOBLMKD_03663 9.7e-138 terC P Protein of unknown function (DUF475)
APOBLMKD_03664 0.0 yceG S Putative component of 'biosynthetic module'
APOBLMKD_03665 6.7e-193 yceH P Belongs to the TelA family
APOBLMKD_03666 2.6e-214 naiP P Uncharacterised MFS-type transporter YbfB
APOBLMKD_03667 3.9e-229 proV 3.6.3.32 E glycine betaine
APOBLMKD_03668 1.6e-138 opuAB P glycine betaine
APOBLMKD_03669 1.5e-163 opuAC E glycine betaine
APOBLMKD_03670 3.1e-209 amhX S amidohydrolase
APOBLMKD_03671 4.9e-228 ycgA S Membrane
APOBLMKD_03672 1e-79 ycgB
APOBLMKD_03673 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
APOBLMKD_03674 5.9e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APOBLMKD_03675 8.1e-261 mdr EGP Major facilitator Superfamily
APOBLMKD_03676 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
APOBLMKD_03677 4.7e-114 ycgF E Lysine exporter protein LysE YggA
APOBLMKD_03678 2.9e-150 yqcI S YqcI/YcgG family
APOBLMKD_03679 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
APOBLMKD_03680 1.3e-113 ycgI S Domain of unknown function (DUF1989)
APOBLMKD_03681 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APOBLMKD_03683 1.4e-107 tmrB S AAA domain
APOBLMKD_03684 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
APOBLMKD_03685 4.8e-222 G COG0477 Permeases of the major facilitator superfamily
APOBLMKD_03686 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APOBLMKD_03687 1.2e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
APOBLMKD_03688 5.8e-146 ycgL S Predicted nucleotidyltransferase
APOBLMKD_03689 1.9e-169 ycgM E Proline dehydrogenase
APOBLMKD_03690 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
APOBLMKD_03691 1.2e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOBLMKD_03692 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
APOBLMKD_03693 4.2e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
APOBLMKD_03694 6.4e-218 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
APOBLMKD_03695 1.1e-55 nirD 1.7.1.15 P Nitrite reductase
APOBLMKD_03696 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APOBLMKD_03697 6e-227 yciC S GTPases (G3E family)
APOBLMKD_03698 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APOBLMKD_03699 4.7e-73 yckC S membrane
APOBLMKD_03700 2.3e-48 S Protein of unknown function (DUF2680)
APOBLMKD_03701 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APOBLMKD_03702 5.7e-65 nin S Competence protein J (ComJ)
APOBLMKD_03703 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
APOBLMKD_03704 1.9e-82 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
APOBLMKD_03705 1.1e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
APOBLMKD_03706 2.6e-61 hxlR K transcriptional
APOBLMKD_03707 2.2e-78 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_03708 3.5e-39 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOBLMKD_03709 1.4e-74 M1-820 Q Collagen triple helix repeat (20 copies)
APOBLMKD_03710 1.3e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APOBLMKD_03711 2.6e-118 citT T response regulator
APOBLMKD_03712 3.5e-177 yflP S Tripartite tricarboxylate transporter family receptor
APOBLMKD_03713 3.6e-225 citM C Citrate transporter
APOBLMKD_03714 4.8e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
APOBLMKD_03715 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
APOBLMKD_03716 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
APOBLMKD_03717 2.2e-122 yflK S protein conserved in bacteria
APOBLMKD_03718 1.5e-14 yflJ S Protein of unknown function (DUF2639)
APOBLMKD_03719 7e-19 yflI
APOBLMKD_03720 3.1e-50 yflH S Protein of unknown function (DUF3243)
APOBLMKD_03721 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
APOBLMKD_03722 2.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
APOBLMKD_03723 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
APOBLMKD_03724 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APOBLMKD_03725 2.3e-63 yhdN S Domain of unknown function (DUF1992)
APOBLMKD_03726 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
APOBLMKD_03727 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
APOBLMKD_03728 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
APOBLMKD_03729 9.5e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOBLMKD_03730 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
APOBLMKD_03731 1.5e-129 treR K transcriptional
APOBLMKD_03732 1.2e-123 yfkO C nitroreductase
APOBLMKD_03733 1e-123 yibF S YibE/F-like protein
APOBLMKD_03734 9.4e-198 yibE S YibE/F-like protein
APOBLMKD_03735 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
APOBLMKD_03736 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
APOBLMKD_03737 9.8e-186 K helix_turn _helix lactose operon repressor
APOBLMKD_03738 5.6e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APOBLMKD_03739 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
APOBLMKD_03740 8.1e-192 ydiM EGP Major facilitator Superfamily
APOBLMKD_03741 2.3e-29 yfkK S Belongs to the UPF0435 family
APOBLMKD_03742 4.6e-35 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APOBLMKD_03743 1.2e-27 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APOBLMKD_03744 1e-51 yfkI S gas vesicle protein
APOBLMKD_03745 7.6e-144 yihY S Belongs to the UPF0761 family
APOBLMKD_03746 2.5e-07
APOBLMKD_03747 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
APOBLMKD_03748 8.5e-185 cax P COG0387 Ca2 H antiporter
APOBLMKD_03749 1.6e-143 yfkD S YfkD-like protein
APOBLMKD_03750 1e-145 yfkC M Mechanosensitive ion channel
APOBLMKD_03751 7.3e-219 yfkA S YfkB-like domain
APOBLMKD_03752 4.9e-27 yfjT
APOBLMKD_03753 9e-155 pdaA G deacetylase
APOBLMKD_03754 7.5e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
APOBLMKD_03755 3.3e-30
APOBLMKD_03756 8.5e-184 corA P Mediates influx of magnesium ions
APOBLMKD_03757 8.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APOBLMKD_03758 1.8e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APOBLMKD_03759 8.7e-44 S YfzA-like protein
APOBLMKD_03760 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APOBLMKD_03761 6.1e-91 yfjM S Psort location Cytoplasmic, score
APOBLMKD_03762 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APOBLMKD_03763 4.7e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APOBLMKD_03764 1.4e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APOBLMKD_03765 1.2e-250 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APOBLMKD_03766 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
APOBLMKD_03767 4.2e-15 sspH S Belongs to the SspH family
APOBLMKD_03768 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APOBLMKD_03769 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
APOBLMKD_03770 3.2e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOBLMKD_03771 2.6e-308 yfiB3 V ABC transporter
APOBLMKD_03772 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
APOBLMKD_03773 9.2e-63 mhqP S DoxX
APOBLMKD_03774 2.2e-159 yfiE 1.13.11.2 S glyoxalase
APOBLMKD_03775 1.7e-163 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APOBLMKD_03776 6.6e-96 padR K transcriptional
APOBLMKD_03777 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
APOBLMKD_03778 1.9e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
APOBLMKD_03779 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
APOBLMKD_03780 4.5e-45 yrdF K ribonuclease inhibitor
APOBLMKD_03781 5.3e-43 yfiT S Belongs to the metal hydrolase YfiT family
APOBLMKD_03782 4.7e-288 yfiU EGP Major facilitator Superfamily
APOBLMKD_03783 8.1e-82 yfiV K transcriptional
APOBLMKD_03784 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APOBLMKD_03785 8.5e-162 yfhB 5.3.3.17 S PhzF family
APOBLMKD_03786 1.7e-105 yfhC C nitroreductase
APOBLMKD_03787 2.1e-25 yfhD S YfhD-like protein
APOBLMKD_03789 7.5e-166 yfhF S nucleoside-diphosphate sugar epimerase
APOBLMKD_03790 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
APOBLMKD_03791 2.5e-52 yfhH S Protein of unknown function (DUF1811)
APOBLMKD_03792 1.1e-204 yfhI EGP Major facilitator Superfamily
APOBLMKD_03794 2e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
APOBLMKD_03795 2.2e-44 yfhJ S WVELL protein
APOBLMKD_03796 8.5e-93 batE T Bacterial SH3 domain homologues
APOBLMKD_03797 9.7e-34 yfhL S SdpI/YhfL protein family
APOBLMKD_03798 9.1e-169 yfhM S Alpha/beta hydrolase family
APOBLMKD_03799 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APOBLMKD_03800 0.0 yfhO S Bacterial membrane protein YfhO
APOBLMKD_03801 1e-184 yfhP S membrane-bound metal-dependent
APOBLMKD_03802 4.8e-207 mutY L A G-specific
APOBLMKD_03803 1.3e-34 yfhS
APOBLMKD_03804 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOBLMKD_03806 1.5e-37 ygaB S YgaB-like protein
APOBLMKD_03807 2.2e-104 ygaC J Belongs to the UPF0374 family
APOBLMKD_03808 3.5e-300 ygaD V ABC transporter
APOBLMKD_03809 2.7e-178 ygaE S Membrane
APOBLMKD_03810 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
APOBLMKD_03811 1.5e-85 bcp 1.11.1.15 O Peroxiredoxin
APOBLMKD_03812 1.8e-80 perR P Belongs to the Fur family
APOBLMKD_03813 1.5e-56 ygzB S UPF0295 protein
APOBLMKD_03814 1.1e-164 ygxA S Nucleotidyltransferase-like

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)