ORF_ID e_value Gene_name EC_number CAZy COGs Description
DOMDFNBG_00001 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
DOMDFNBG_00002 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOMDFNBG_00003 3.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
DOMDFNBG_00004 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
DOMDFNBG_00005 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DOMDFNBG_00007 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DOMDFNBG_00009 1.2e-61 KT phosphorelay signal transduction system
DOMDFNBG_00010 7e-34 S Protein of unknown function (DUF3021)
DOMDFNBG_00011 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DOMDFNBG_00012 1.5e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
DOMDFNBG_00013 8.2e-70 argR K Regulates arginine biosynthesis genes
DOMDFNBG_00014 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
DOMDFNBG_00015 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DOMDFNBG_00016 9.2e-141 1.1.1.169 H Ketopantoate reductase
DOMDFNBG_00017 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DOMDFNBG_00018 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DOMDFNBG_00019 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
DOMDFNBG_00020 2.3e-161 S CHAP domain
DOMDFNBG_00021 2e-32 L Integrase core domain protein
DOMDFNBG_00022 3.5e-50 L transposition
DOMDFNBG_00023 1.1e-89 L transposase activity
DOMDFNBG_00024 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DOMDFNBG_00025 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOMDFNBG_00026 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DOMDFNBG_00027 3.8e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DOMDFNBG_00028 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOMDFNBG_00029 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DOMDFNBG_00030 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOMDFNBG_00031 1.1e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DOMDFNBG_00032 7e-144 recO L Involved in DNA repair and RecF pathway recombination
DOMDFNBG_00033 2.9e-218 araT 2.6.1.1 E Aminotransferase
DOMDFNBG_00034 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOMDFNBG_00035 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
DOMDFNBG_00036 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DOMDFNBG_00037 5.5e-139 mreC M Involved in formation and maintenance of cell shape
DOMDFNBG_00041 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
DOMDFNBG_00042 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DOMDFNBG_00043 2e-126 gntR1 K transcriptional
DOMDFNBG_00044 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DOMDFNBG_00045 1.4e-273 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOMDFNBG_00046 3.1e-87 niaX
DOMDFNBG_00047 1e-17 niaR S small molecule binding protein (contains 3H domain)
DOMDFNBG_00048 2e-45 niaR S small molecule binding protein (contains 3H domain)
DOMDFNBG_00049 1.6e-128 K DNA-binding helix-turn-helix protein
DOMDFNBG_00050 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DOMDFNBG_00051 2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOMDFNBG_00052 4.1e-167 GK ROK family
DOMDFNBG_00053 3.2e-158 dprA LU DNA protecting protein DprA
DOMDFNBG_00054 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOMDFNBG_00055 1.4e-150 S TraX protein
DOMDFNBG_00056 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOMDFNBG_00057 1.3e-252 T PhoQ Sensor
DOMDFNBG_00058 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DOMDFNBG_00059 4.2e-152 XK27_05470 E Methionine synthase
DOMDFNBG_00060 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
DOMDFNBG_00061 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOMDFNBG_00062 6e-43 IQ Acetoin reductase
DOMDFNBG_00063 3.9e-19 IQ Acetoin reductase
DOMDFNBG_00064 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DOMDFNBG_00065 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DOMDFNBG_00068 1.1e-212 pqqE C radical SAM domain protein
DOMDFNBG_00069 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
DOMDFNBG_00070 6.6e-61 EGP Major facilitator Superfamily
DOMDFNBG_00071 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DOMDFNBG_00072 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
DOMDFNBG_00073 4.3e-13
DOMDFNBG_00074 1.5e-42 L Transposase
DOMDFNBG_00075 9.1e-83 L Integrase core domain protein
DOMDFNBG_00076 6.5e-67 L Transposase
DOMDFNBG_00077 3.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DOMDFNBG_00078 8.3e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DOMDFNBG_00079 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOMDFNBG_00080 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
DOMDFNBG_00081 1.5e-103 yjbK S Adenylate cyclase
DOMDFNBG_00082 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOMDFNBG_00083 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
DOMDFNBG_00084 3.1e-59 XK27_04120 S Putative amino acid metabolism
DOMDFNBG_00085 1.1e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DOMDFNBG_00086 4.8e-128 puuD T peptidase C26
DOMDFNBG_00087 1.2e-115 radC E Belongs to the UPF0758 family
DOMDFNBG_00088 1.7e-268 M Psort location CytoplasmicMembrane, score
DOMDFNBG_00089 0.0 rgpF M Rhamnan synthesis protein F
DOMDFNBG_00090 4.5e-305 GT4 M transferase activity, transferring glycosyl groups
DOMDFNBG_00091 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DOMDFNBG_00092 1.8e-142 rgpC GM Transport permease protein
DOMDFNBG_00093 6.4e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
DOMDFNBG_00094 2.3e-228 rgpA GT4 M Domain of unknown function (DUF1972)
DOMDFNBG_00095 2.4e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
DOMDFNBG_00096 4.6e-42 S Uncharacterized conserved protein (DUF2304)
DOMDFNBG_00097 6.9e-130 arnC M group 2 family protein
DOMDFNBG_00098 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
DOMDFNBG_00099 1e-184 S Glycosyltransferase like family 2
DOMDFNBG_00100 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
DOMDFNBG_00101 2.6e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DOMDFNBG_00102 2e-236 S Predicted membrane protein (DUF2142)
DOMDFNBG_00103 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
DOMDFNBG_00104 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
DOMDFNBG_00105 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DOMDFNBG_00106 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DOMDFNBG_00107 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DOMDFNBG_00108 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
DOMDFNBG_00109 2.1e-202 arcT 2.6.1.1 E Aminotransferase
DOMDFNBG_00110 9.4e-136 ET ABC transporter
DOMDFNBG_00111 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
DOMDFNBG_00112 2.9e-84 mutT 3.6.1.55 F Nudix family
DOMDFNBG_00113 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DOMDFNBG_00115 2e-78 S CAAX amino terminal protease family protein
DOMDFNBG_00116 7.6e-32 S CAAX amino terminal protease family protein
DOMDFNBG_00117 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
DOMDFNBG_00118 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
DOMDFNBG_00119 1.1e-16 XK27_00735
DOMDFNBG_00120 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DOMDFNBG_00122 6.2e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOMDFNBG_00125 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
DOMDFNBG_00126 6.6e-30 ycaO O OsmC-like protein
DOMDFNBG_00128 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
DOMDFNBG_00130 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
DOMDFNBG_00131 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOMDFNBG_00132 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOMDFNBG_00133 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DOMDFNBG_00134 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
DOMDFNBG_00135 1.6e-297 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DOMDFNBG_00136 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOMDFNBG_00137 2.6e-109 3.1.3.18 S IA, variant 1
DOMDFNBG_00138 2.2e-117 lrgB M effector of murein hydrolase
DOMDFNBG_00139 7.7e-56 lrgA S Effector of murein hydrolase LrgA
DOMDFNBG_00141 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
DOMDFNBG_00142 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
DOMDFNBG_00143 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOMDFNBG_00144 1.3e-104 wecD M Acetyltransferase (GNAT) domain
DOMDFNBG_00145 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DOMDFNBG_00146 5.1e-96 GK ROK family
DOMDFNBG_00147 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
DOMDFNBG_00148 6.6e-62 XK27_08050 O stress-induced mitochondrial fusion
DOMDFNBG_00149 9.6e-26 XK27_08050 O HflC and HflK could regulate a protease
DOMDFNBG_00150 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
DOMDFNBG_00151 2.3e-206 potD P spermidine putrescine ABC transporter
DOMDFNBG_00152 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
DOMDFNBG_00153 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
DOMDFNBG_00154 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DOMDFNBG_00155 2.3e-170 murB 1.3.1.98 M cell wall formation
DOMDFNBG_00156 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DOMDFNBG_00157 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DOMDFNBG_00158 6e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
DOMDFNBG_00159 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DOMDFNBG_00160 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
DOMDFNBG_00161 0.0 ydaO E amino acid
DOMDFNBG_00162 2.1e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DOMDFNBG_00163 4.1e-37 ylqC L Belongs to the UPF0109 family
DOMDFNBG_00164 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DOMDFNBG_00165 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
DOMDFNBG_00166 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
DOMDFNBG_00167 2.1e-74 S QueT transporter
DOMDFNBG_00168 4.9e-120 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
DOMDFNBG_00169 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DOMDFNBG_00170 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOMDFNBG_00171 3.7e-85 ccl S cog cog4708
DOMDFNBG_00172 2.8e-163 rbn E Belongs to the UPF0761 family
DOMDFNBG_00173 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
DOMDFNBG_00174 3.3e-231 ytoI K transcriptional regulator containing CBS domains
DOMDFNBG_00175 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
DOMDFNBG_00176 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOMDFNBG_00177 0.0 comEC S Competence protein ComEC
DOMDFNBG_00178 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
DOMDFNBG_00179 1.3e-142 plsC 2.3.1.51 I Acyltransferase
DOMDFNBG_00180 4.4e-73 nodB3 G polysaccharide deacetylase
DOMDFNBG_00181 1.5e-61 nodB3 G deacetylase
DOMDFNBG_00182 7.1e-141 yabB 2.1.1.223 L Methyltransferase
DOMDFNBG_00183 1e-41 yazA L endonuclease containing a URI domain
DOMDFNBG_00184 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DOMDFNBG_00185 3.9e-154 corA P CorA-like protein
DOMDFNBG_00186 1.9e-62 yjqA S Bacterial PH domain
DOMDFNBG_00187 7.8e-100 thiT S Thiamine transporter
DOMDFNBG_00188 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DOMDFNBG_00189 6e-175 yjbB G Permeases of the major facilitator superfamily
DOMDFNBG_00190 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DOMDFNBG_00191 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
DOMDFNBG_00192 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DOMDFNBG_00196 1.1e-155 cjaA ET ABC transporter substrate-binding protein
DOMDFNBG_00197 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
DOMDFNBG_00198 1.3e-114 P ABC transporter (Permease
DOMDFNBG_00199 1e-114 papP P ABC transporter (Permease
DOMDFNBG_00200 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DOMDFNBG_00201 2e-29 copZ 2.7.7.77 P Heavy metal-associated domain protein
DOMDFNBG_00202 0.0 copA 3.6.3.54 P P-type ATPase
DOMDFNBG_00203 2.7e-73 copY K Copper transport repressor, CopY TcrY family
DOMDFNBG_00204 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DOMDFNBG_00205 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DOMDFNBG_00206 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
DOMDFNBG_00207 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
DOMDFNBG_00208 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DOMDFNBG_00209 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
DOMDFNBG_00210 2.4e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DOMDFNBG_00211 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
DOMDFNBG_00212 3.2e-56
DOMDFNBG_00213 0.0 ctpE P E1-E2 ATPase
DOMDFNBG_00214 3.9e-26
DOMDFNBG_00215 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOMDFNBG_00216 9.7e-28 L transposase activity
DOMDFNBG_00217 2.7e-129 K transcriptional regulator, MerR family
DOMDFNBG_00218 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
DOMDFNBG_00219 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
DOMDFNBG_00220 4.8e-63 XK27_02560 S cog cog2151
DOMDFNBG_00221 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DOMDFNBG_00222 7.7e-227 ytfP S Flavoprotein
DOMDFNBG_00224 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DOMDFNBG_00225 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
DOMDFNBG_00226 3e-182 ecsB U ABC transporter
DOMDFNBG_00227 2.3e-133 ecsA V abc transporter atp-binding protein
DOMDFNBG_00228 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
DOMDFNBG_00229 5.6e-12
DOMDFNBG_00230 8.1e-106
DOMDFNBG_00231 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
DOMDFNBG_00232 6.9e-206 ylbM S Belongs to the UPF0348 family
DOMDFNBG_00233 2e-140 yqeM Q Methyltransferase domain protein
DOMDFNBG_00234 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DOMDFNBG_00235 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
DOMDFNBG_00236 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DOMDFNBG_00237 3.5e-49 yhbY J RNA-binding protein
DOMDFNBG_00238 8.4e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
DOMDFNBG_00239 1.8e-98 yqeG S hydrolase of the HAD superfamily
DOMDFNBG_00240 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DOMDFNBG_00241 1.3e-57
DOMDFNBG_00242 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOMDFNBG_00243 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DOMDFNBG_00244 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOMDFNBG_00245 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
DOMDFNBG_00246 2.9e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOMDFNBG_00247 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOMDFNBG_00248 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOMDFNBG_00249 1.1e-153 hlpA M Belongs to the NlpA lipoprotein family
DOMDFNBG_00250 6.8e-101 pncA Q isochorismatase
DOMDFNBG_00251 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DOMDFNBG_00252 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
DOMDFNBG_00253 2.4e-75 XK27_03180 T universal stress protein
DOMDFNBG_00256 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DOMDFNBG_00257 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
DOMDFNBG_00258 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
DOMDFNBG_00259 0.0 yjcE P NhaP-type Na H and K H antiporters
DOMDFNBG_00261 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
DOMDFNBG_00262 1.3e-184 yhcC S radical SAM protein
DOMDFNBG_00263 2.2e-196 ylbL T Belongs to the peptidase S16 family
DOMDFNBG_00264 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DOMDFNBG_00265 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
DOMDFNBG_00266 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DOMDFNBG_00267 1.9e-09 S Protein of unknown function (DUF4059)
DOMDFNBG_00268 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
DOMDFNBG_00269 1e-162 yxeN P ABC transporter (Permease
DOMDFNBG_00270 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
DOMDFNBG_00272 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOMDFNBG_00273 0.0 pflB 2.3.1.54 C formate acetyltransferase'
DOMDFNBG_00274 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
DOMDFNBG_00275 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOMDFNBG_00276 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
DOMDFNBG_00277 2.9e-87 D nuclear chromosome segregation
DOMDFNBG_00278 1.5e-127 ybbM S transport system, permease component
DOMDFNBG_00279 3.6e-117 ybbL S abc transporter atp-binding protein
DOMDFNBG_00280 6.5e-184 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
DOMDFNBG_00281 1.7e-139 cppA E CppA N-terminal
DOMDFNBG_00282 5e-44 V CAAX protease self-immunity
DOMDFNBG_00283 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DOMDFNBG_00284 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DOMDFNBG_00287 6.8e-47 spiA K sequence-specific DNA binding
DOMDFNBG_00288 2.9e-28 blpT
DOMDFNBG_00289 1.2e-91 blpT
DOMDFNBG_00290 3.9e-299 res_1 3.1.21.5 S DEAD-like helicases superfamily
DOMDFNBG_00292 8.5e-112 int L Belongs to the 'phage' integrase family
DOMDFNBG_00293 3.4e-83 int L Belongs to the 'phage' integrase family
DOMDFNBG_00294 2.2e-35 S Helix-turn-helix domain
DOMDFNBG_00296 2.4e-117
DOMDFNBG_00298 6.9e-53 isp2 S pathogenesis
DOMDFNBG_00299 2.9e-125 tnp L Transposase IS66 family
DOMDFNBG_00300 3.7e-224 capA M Bacterial capsule synthesis protein
DOMDFNBG_00301 3.6e-39 gcvR T UPF0237 protein
DOMDFNBG_00302 1.9e-242 XK27_08635 S UPF0210 protein
DOMDFNBG_00303 2.2e-38 ais G alpha-ribazole phosphatase activity
DOMDFNBG_00304 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
DOMDFNBG_00305 1.3e-102 acmA 3.2.1.17 NU amidase activity
DOMDFNBG_00306 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DOMDFNBG_00307 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOMDFNBG_00308 9.8e-298 dnaK O Heat shock 70 kDa protein
DOMDFNBG_00309 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DOMDFNBG_00310 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DOMDFNBG_00311 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
DOMDFNBG_00312 1.7e-60 hmpT S membrane
DOMDFNBG_00313 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
DOMDFNBG_00314 2.8e-164 hrtB V MacB-like periplasmic core domain
DOMDFNBG_00318 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DOMDFNBG_00319 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DOMDFNBG_00320 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DOMDFNBG_00321 1.2e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DOMDFNBG_00322 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
DOMDFNBG_00323 6.3e-108 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DOMDFNBG_00324 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DOMDFNBG_00325 5.8e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DOMDFNBG_00326 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DOMDFNBG_00327 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
DOMDFNBG_00328 5.6e-240 rodA D Belongs to the SEDS family
DOMDFNBG_00329 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOMDFNBG_00330 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
DOMDFNBG_00331 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DOMDFNBG_00332 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DOMDFNBG_00333 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
DOMDFNBG_00334 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOMDFNBG_00335 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DOMDFNBG_00336 2.9e-125 dnaD
DOMDFNBG_00337 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOMDFNBG_00340 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOMDFNBG_00341 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
DOMDFNBG_00342 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOMDFNBG_00343 4.3e-158 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DOMDFNBG_00344 1.8e-72 argR K Regulates arginine biosynthesis genes
DOMDFNBG_00345 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
DOMDFNBG_00346 1e-148 DegV S DegV family
DOMDFNBG_00347 6e-144 ypmR E lipolytic protein G-D-S-L family
DOMDFNBG_00348 2.1e-84 ypmS S Protein conserved in bacteria
DOMDFNBG_00349 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DOMDFNBG_00351 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
DOMDFNBG_00352 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOMDFNBG_00353 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DOMDFNBG_00354 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DOMDFNBG_00355 3.3e-43 ysdA L Membrane
DOMDFNBG_00356 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DOMDFNBG_00357 1.2e-111 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DOMDFNBG_00358 4.1e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
DOMDFNBG_00359 0.0 dnaE 2.7.7.7 L DNA polymerase
DOMDFNBG_00360 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DOMDFNBG_00361 3.9e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DOMDFNBG_00364 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
DOMDFNBG_00365 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
DOMDFNBG_00367 1.6e-16 S Domain of unknown function (DUF4649)
DOMDFNBG_00368 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
DOMDFNBG_00369 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
DOMDFNBG_00370 1.2e-135 XK27_08845 S abc transporter atp-binding protein
DOMDFNBG_00371 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOMDFNBG_00372 3.5e-151 estA CE1 S Putative esterase
DOMDFNBG_00373 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
DOMDFNBG_00374 3.3e-14 XK27_08880
DOMDFNBG_00375 2.3e-75 fld C Flavodoxin
DOMDFNBG_00376 3.7e-282 clcA P Chloride transporter, ClC family
DOMDFNBG_00377 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
DOMDFNBG_00378 3.2e-220 XK27_05110 P chloride
DOMDFNBG_00379 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DOMDFNBG_00382 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
DOMDFNBG_00383 1.3e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOMDFNBG_00384 6.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
DOMDFNBG_00385 4.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOMDFNBG_00386 1.2e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DOMDFNBG_00387 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DOMDFNBG_00388 3.5e-26 G Domain of unknown function (DUF4832)
DOMDFNBG_00389 1.9e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DOMDFNBG_00391 9.4e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOMDFNBG_00392 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
DOMDFNBG_00393 3.5e-123 endA F DNA RNA non-specific endonuclease
DOMDFNBG_00394 2.5e-110 tcyB_2 P ABC transporter (permease)
DOMDFNBG_00395 8e-115 gltJ P ABC transporter (Permease
DOMDFNBG_00396 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
DOMDFNBG_00397 3.3e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
DOMDFNBG_00398 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOMDFNBG_00399 1.4e-245 vicK 2.7.13.3 T Histidine kinase
DOMDFNBG_00400 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
DOMDFNBG_00401 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
DOMDFNBG_00402 9.2e-147 yidA S hydrolases of the HAD superfamily
DOMDFNBG_00403 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
DOMDFNBG_00404 2.6e-67 ywiB S Domain of unknown function (DUF1934)
DOMDFNBG_00405 0.0 pacL 3.6.3.8 P cation transport ATPase
DOMDFNBG_00406 1.5e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DOMDFNBG_00407 1.3e-181 yjjH S Calcineurin-like phosphoesterase
DOMDFNBG_00408 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DOMDFNBG_00409 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DOMDFNBG_00410 2.5e-124 ftsE D cell division ATP-binding protein FtsE
DOMDFNBG_00411 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
DOMDFNBG_00412 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
DOMDFNBG_00413 6.2e-176 yubA S permease
DOMDFNBG_00414 2.4e-223 G COG0457 FOG TPR repeat
DOMDFNBG_00415 1.8e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DOMDFNBG_00416 1.1e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DOMDFNBG_00417 2.9e-90 ebsA S Family of unknown function (DUF5322)
DOMDFNBG_00418 2.8e-18 M LysM domain
DOMDFNBG_00419 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DOMDFNBG_00420 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOMDFNBG_00421 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DOMDFNBG_00422 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DOMDFNBG_00423 1.8e-147 L Transposase
DOMDFNBG_00424 5.6e-20 rmlC 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
DOMDFNBG_00425 2.7e-160 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DOMDFNBG_00426 7.3e-248 cps1C S Polysaccharide biosynthesis protein
DOMDFNBG_00427 1.2e-141 cps1B GT2,GT4 M Glycosyl transferases group 1
DOMDFNBG_00428 1.7e-36 S Psort location CytoplasmicMembrane, score 9.99
DOMDFNBG_00429 2.9e-80 sacB GT2,GT4 M transferase activity, transferring glycosyl groups
DOMDFNBG_00430 7.8e-60 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
DOMDFNBG_00431 1.1e-149 M Glycosyltransferase, group 2 family protein
DOMDFNBG_00432 8.5e-87 Z012_10770 M Domain of unknown function (DUF1919)
DOMDFNBG_00433 1.1e-209 wcoF M Glycosyltransferase, group 1 family protein
DOMDFNBG_00434 4.5e-219 rgpAc GT4 M group 1 family protein
DOMDFNBG_00435 2.7e-255 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
DOMDFNBG_00436 1.1e-117 cpsD D COG0489 ATPases involved in chromosome partitioning
DOMDFNBG_00437 4.7e-107 cps4C M biosynthesis protein
DOMDFNBG_00438 1.1e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
DOMDFNBG_00439 1.5e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
DOMDFNBG_00440 5.8e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
DOMDFNBG_00441 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
DOMDFNBG_00442 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
DOMDFNBG_00443 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DOMDFNBG_00444 9.3e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
DOMDFNBG_00445 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DOMDFNBG_00447 6.1e-22 V Glucan-binding protein C
DOMDFNBG_00448 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
DOMDFNBG_00449 9e-275 pepV 3.5.1.18 E Dipeptidase
DOMDFNBG_00450 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DOMDFNBG_00451 2e-85 XK27_03610 K Gnat family
DOMDFNBG_00452 9.1e-10 L COG1943 Transposase and inactivated derivatives
DOMDFNBG_00453 1.3e-22 XK27_08085
DOMDFNBG_00454 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
DOMDFNBG_00455 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
DOMDFNBG_00456 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
DOMDFNBG_00457 1.1e-121 ylfI S tigr01906
DOMDFNBG_00458 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DOMDFNBG_00459 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
DOMDFNBG_00460 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
DOMDFNBG_00463 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DOMDFNBG_00464 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DOMDFNBG_00465 4.1e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DOMDFNBG_00466 1.1e-206 yurR 1.4.5.1 E oxidoreductase
DOMDFNBG_00467 6.3e-101 zupT P Mediates zinc uptake. May also transport other divalent cations
DOMDFNBG_00468 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOMDFNBG_00469 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
DOMDFNBG_00470 1.7e-70 gtrA S GtrA-like protein
DOMDFNBG_00471 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOMDFNBG_00472 6e-169 ybbR S Protein conserved in bacteria
DOMDFNBG_00473 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOMDFNBG_00474 1.8e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
DOMDFNBG_00475 8.7e-150 cobQ S glutamine amidotransferase
DOMDFNBG_00476 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOMDFNBG_00477 1.4e-130 pip 1.11.1.10 S Alpha beta hydrolase
DOMDFNBG_00479 0.0 uup S abc transporter atp-binding protein
DOMDFNBG_00480 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
DOMDFNBG_00481 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
DOMDFNBG_00482 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DOMDFNBG_00483 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
DOMDFNBG_00484 1.1e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DOMDFNBG_00485 6.5e-63 manO S protein conserved in bacteria
DOMDFNBG_00486 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
DOMDFNBG_00487 1.7e-116 manM G pts system
DOMDFNBG_00488 1.1e-181 manL 2.7.1.191 G pts system
DOMDFNBG_00489 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
DOMDFNBG_00490 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
DOMDFNBG_00491 1.9e-248 pbuO S permease
DOMDFNBG_00492 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
DOMDFNBG_00493 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
DOMDFNBG_00494 2.5e-220 brpA K Transcriptional
DOMDFNBG_00495 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
DOMDFNBG_00496 3.1e-212 nusA K Participates in both transcription termination and antitermination
DOMDFNBG_00497 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
DOMDFNBG_00498 1.4e-41 ylxQ J ribosomal protein
DOMDFNBG_00499 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DOMDFNBG_00500 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DOMDFNBG_00501 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
DOMDFNBG_00502 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
DOMDFNBG_00504 2.1e-213 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
DOMDFNBG_00505 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOMDFNBG_00506 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
DOMDFNBG_00507 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
DOMDFNBG_00508 1e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
DOMDFNBG_00509 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
DOMDFNBG_00511 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DOMDFNBG_00512 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DOMDFNBG_00513 3.4e-74 ylbF S Belongs to the UPF0342 family
DOMDFNBG_00514 7.1e-46 ylbG S UPF0298 protein
DOMDFNBG_00515 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
DOMDFNBG_00516 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
DOMDFNBG_00517 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
DOMDFNBG_00518 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
DOMDFNBG_00519 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
DOMDFNBG_00520 2.8e-70 acuB S IMP dehydrogenase activity
DOMDFNBG_00521 3.3e-43 acuB S IMP dehydrogenase activity
DOMDFNBG_00522 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOMDFNBG_00523 6.3e-111 yvyE 3.4.13.9 S YigZ family
DOMDFNBG_00524 1.8e-253 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DOMDFNBG_00525 4.4e-123 comFC S Competence protein
DOMDFNBG_00526 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DOMDFNBG_00527 6.4e-104 V ABC transporter (Permease
DOMDFNBG_00528 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DOMDFNBG_00529 1.6e-10
DOMDFNBG_00530 9e-98 K Transcriptional regulator, TetR family
DOMDFNBG_00531 1.8e-159 czcD P cation diffusion facilitator family transporter
DOMDFNBG_00532 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
DOMDFNBG_00533 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
DOMDFNBG_00534 6e-08 S Hydrolases of the alpha beta superfamily
DOMDFNBG_00535 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
DOMDFNBG_00536 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
DOMDFNBG_00539 2.6e-143 2.4.2.3 F Phosphorylase superfamily
DOMDFNBG_00540 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
DOMDFNBG_00541 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
DOMDFNBG_00542 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
DOMDFNBG_00543 3.9e-15 dinF V Mate efflux family protein
DOMDFNBG_00545 2.1e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
DOMDFNBG_00546 3.7e-190
DOMDFNBG_00547 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
DOMDFNBG_00548 3.5e-28 3.4.13.21 I Protein conserved in bacteria
DOMDFNBG_00550 3.7e-117 S TraX protein
DOMDFNBG_00551 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
DOMDFNBG_00552 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
DOMDFNBG_00553 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DOMDFNBG_00554 1.2e-180 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOMDFNBG_00555 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOMDFNBG_00556 6.8e-133 cas6 S Pfam:DUF2276
DOMDFNBG_00557 0.0 csm1 S CRISPR-associated protein Csm1 family
DOMDFNBG_00558 5.6e-62 csm2 L Pfam:DUF310
DOMDFNBG_00559 1.1e-116 csm3 L RAMP superfamily
DOMDFNBG_00560 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
DOMDFNBG_00561 2.2e-204 csm5 L CRISPR-associated RAMP protein, Csm5 family
DOMDFNBG_00562 2.1e-14 csm6 S Psort location Cytoplasmic, score
DOMDFNBG_00563 5.2e-74 csm6 S Psort location Cytoplasmic, score
DOMDFNBG_00564 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DOMDFNBG_00565 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOMDFNBG_00566 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
DOMDFNBG_00568 1.1e-267 dtpT E transporter
DOMDFNBG_00569 8.5e-103 nylA 3.5.1.4 J Belongs to the amidase family
DOMDFNBG_00570 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
DOMDFNBG_00571 1.8e-67 yecS P ABC transporter (Permease
DOMDFNBG_00573 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
DOMDFNBG_00574 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
DOMDFNBG_00575 1.4e-104 yfiF3 K sequence-specific DNA binding
DOMDFNBG_00576 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DOMDFNBG_00577 1.8e-240 agcS E (Alanine) symporter
DOMDFNBG_00578 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DOMDFNBG_00579 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
DOMDFNBG_00580 1.8e-59 Q phosphatase activity
DOMDFNBG_00581 9.3e-62 S haloacid dehalogenase-like hydrolase
DOMDFNBG_00582 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DOMDFNBG_00583 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
DOMDFNBG_00584 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
DOMDFNBG_00585 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
DOMDFNBG_00586 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOMDFNBG_00587 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DOMDFNBG_00588 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DOMDFNBG_00589 1.9e-43 yktA S Belongs to the UPF0223 family
DOMDFNBG_00590 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
DOMDFNBG_00591 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
DOMDFNBG_00592 3.3e-158 pstS P phosphate
DOMDFNBG_00593 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
DOMDFNBG_00594 1.2e-155 pstA P phosphate transport system permease
DOMDFNBG_00595 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOMDFNBG_00596 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOMDFNBG_00597 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
DOMDFNBG_00598 0.0 pepN 3.4.11.2 E aminopeptidase
DOMDFNBG_00599 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
DOMDFNBG_00600 1.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
DOMDFNBG_00603 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DOMDFNBG_00604 1.2e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
DOMDFNBG_00605 2.3e-23 L Transposase
DOMDFNBG_00606 4.6e-25 tatA U protein secretion
DOMDFNBG_00607 2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DOMDFNBG_00608 3.5e-297 ywbL P COG0672 High-affinity Fe2 Pb2 permease
DOMDFNBG_00609 1.6e-232 ycdB P peroxidase
DOMDFNBG_00610 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
DOMDFNBG_00611 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
DOMDFNBG_00612 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
DOMDFNBG_00613 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOMDFNBG_00614 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOMDFNBG_00615 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOMDFNBG_00616 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOMDFNBG_00617 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOMDFNBG_00618 6.1e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOMDFNBG_00619 4.4e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOMDFNBG_00620 1.9e-37 3.5.1.28 NU amidase activity
DOMDFNBG_00621 8.5e-266 3.5.1.28 NU amidase activity
DOMDFNBG_00622 1.6e-83 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DOMDFNBG_00623 0.0 lpdA 1.8.1.4 C Dehydrogenase
DOMDFNBG_00624 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DOMDFNBG_00625 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DOMDFNBG_00626 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
DOMDFNBG_00627 5e-38 P membrane protein (DUF2207)
DOMDFNBG_00628 1.8e-64 S the current gene model (or a revised gene model) may contain a frame shift
DOMDFNBG_00629 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DOMDFNBG_00630 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DOMDFNBG_00631 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOMDFNBG_00632 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
DOMDFNBG_00633 3.4e-22 3.4.16.4 M Belongs to the peptidase S11 family
DOMDFNBG_00634 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
DOMDFNBG_00635 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
DOMDFNBG_00636 1.2e-157 rssA S Phospholipase, patatin family
DOMDFNBG_00637 3.9e-78 estA E GDSL-like protein
DOMDFNBG_00638 2.6e-15 estA E Lysophospholipase L1 and related esterases
DOMDFNBG_00639 5.3e-292 S unusual protein kinase
DOMDFNBG_00640 4.9e-39 S granule-associated protein
DOMDFNBG_00641 4.6e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOMDFNBG_00642 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOMDFNBG_00643 1.3e-199 S hmm pf01594
DOMDFNBG_00644 1.1e-87 G Belongs to the phosphoglycerate mutase family
DOMDFNBG_00645 8.4e-69 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
DOMDFNBG_00646 9.2e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
DOMDFNBG_00647 5.8e-95 V VanZ like family
DOMDFNBG_00648 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DOMDFNBG_00649 1.6e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DOMDFNBG_00650 1.2e-26 ytrF V efflux transmembrane transporter activity
DOMDFNBG_00651 3.1e-31 V efflux transmembrane transporter activity
DOMDFNBG_00652 3.6e-35 V efflux transmembrane transporter activity
DOMDFNBG_00653 4.4e-30 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOMDFNBG_00654 6.4e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
DOMDFNBG_00655 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
DOMDFNBG_00656 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
DOMDFNBG_00657 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DOMDFNBG_00658 4.9e-227 pyrP F uracil Permease
DOMDFNBG_00659 4e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DOMDFNBG_00660 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOMDFNBG_00661 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOMDFNBG_00662 1.8e-167 fhuR K transcriptional regulator (lysR family)
DOMDFNBG_00667 1.6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOMDFNBG_00668 3.3e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
DOMDFNBG_00669 4.2e-119 pts33BCA G pts system
DOMDFNBG_00670 1.4e-47 pts33BCA G pts system
DOMDFNBG_00671 1.5e-25 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DOMDFNBG_00672 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
DOMDFNBG_00673 1.8e-254 cycA E permease
DOMDFNBG_00674 4.5e-39 ynzC S UPF0291 protein
DOMDFNBG_00675 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DOMDFNBG_00676 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DOMDFNBG_00677 6.1e-63 S membrane
DOMDFNBG_00678 1.5e-59
DOMDFNBG_00679 7.5e-26
DOMDFNBG_00680 1.8e-53
DOMDFNBG_00681 3.6e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DOMDFNBG_00682 2.1e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
DOMDFNBG_00683 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
DOMDFNBG_00684 4.9e-106 mur1 NU mannosyl-glycoprotein
DOMDFNBG_00685 1.1e-53 glnB K Belongs to the P(II) protein family
DOMDFNBG_00686 5.2e-226 amt P Ammonium Transporter
DOMDFNBG_00687 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DOMDFNBG_00688 9.5e-55 yabA L Involved in initiation control of chromosome replication
DOMDFNBG_00689 1.2e-135 yaaT S stage 0 sporulation protein
DOMDFNBG_00690 6.4e-162 holB 2.7.7.7 L dna polymerase iii
DOMDFNBG_00691 1.1e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DOMDFNBG_00692 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOMDFNBG_00693 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOMDFNBG_00694 2.8e-230 ftsW D Belongs to the SEDS family
DOMDFNBG_00695 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DOMDFNBG_00696 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DOMDFNBG_00697 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DOMDFNBG_00698 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DOMDFNBG_00699 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOMDFNBG_00700 3.3e-78 atpF C ATP synthase F(0) sector subunit b
DOMDFNBG_00701 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
DOMDFNBG_00702 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOMDFNBG_00703 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DOMDFNBG_00704 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOMDFNBG_00705 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DOMDFNBG_00706 8.9e-14 coiA 3.6.4.12 S Competence protein
DOMDFNBG_00707 2.2e-15 T peptidase
DOMDFNBG_00708 5.5e-153 rarD S Transporter
DOMDFNBG_00709 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DOMDFNBG_00710 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
DOMDFNBG_00711 1.2e-138 yxkH G deacetylase
DOMDFNBG_00712 9e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
DOMDFNBG_00713 2.1e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DOMDFNBG_00714 8.6e-210 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DOMDFNBG_00715 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DOMDFNBG_00716 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
DOMDFNBG_00717 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DOMDFNBG_00718 5.6e-119 3.4.17.14, 3.5.1.28 NU amidase activity
DOMDFNBG_00719 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DOMDFNBG_00720 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DOMDFNBG_00721 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DOMDFNBG_00722 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
DOMDFNBG_00723 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
DOMDFNBG_00724 0.0 pepF E oligoendopeptidase F
DOMDFNBG_00725 1.4e-186 coiA 3.6.4.12 S Competence protein
DOMDFNBG_00726 9.2e-164 K transcriptional regulator (lysR family)
DOMDFNBG_00727 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOMDFNBG_00731 8e-191 phoH T phosphate starvation-inducible protein PhoH
DOMDFNBG_00732 2.3e-61 rlpA M LysM domain protein
DOMDFNBG_00733 2.2e-130 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
DOMDFNBG_00734 7.4e-35 yozE S Belongs to the UPF0346 family
DOMDFNBG_00735 5.3e-161 cvfB S Protein conserved in bacteria
DOMDFNBG_00736 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DOMDFNBG_00737 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DOMDFNBG_00738 3.2e-78 sptS 2.7.13.3 T Histidine kinase
DOMDFNBG_00739 5.4e-45 K Acetyltransferase (GNAT) family
DOMDFNBG_00740 0.0 lmrA2 V abc transporter atp-binding protein
DOMDFNBG_00741 0.0 lmrA1 V abc transporter atp-binding protein
DOMDFNBG_00742 1.9e-77 K DNA-binding transcription factor activity
DOMDFNBG_00743 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DOMDFNBG_00744 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DOMDFNBG_00745 3.8e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
DOMDFNBG_00746 1e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
DOMDFNBG_00747 3.3e-25 U response to pH
DOMDFNBG_00748 0.0 yfmR S abc transporter atp-binding protein
DOMDFNBG_00749 9e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DOMDFNBG_00750 4.3e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DOMDFNBG_00751 2.1e-74 XK27_08360 S EDD domain protein, DegV family
DOMDFNBG_00752 6.4e-61 XK27_08360 S EDD domain protein, DegV family
DOMDFNBG_00753 2.6e-64 WQ51_03320 S cog cog4835
DOMDFNBG_00754 2e-126 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOMDFNBG_00755 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DOMDFNBG_00756 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
DOMDFNBG_00757 6.4e-29 2.3.1.128 K acetyltransferase
DOMDFNBG_00758 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
DOMDFNBG_00759 3.2e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DOMDFNBG_00760 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOMDFNBG_00761 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
DOMDFNBG_00763 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DOMDFNBG_00764 2.1e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOMDFNBG_00765 1.2e-34 fruA 2.7.1.202 G phosphotransferase system
DOMDFNBG_00766 2.7e-126 fruA 2.7.1.202 G phosphotransferase system
DOMDFNBG_00767 2.2e-49 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
DOMDFNBG_00768 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
DOMDFNBG_00769 2.1e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DOMDFNBG_00770 5.6e-114 fruR K transcriptional
DOMDFNBG_00771 6.8e-84 L Transposase
DOMDFNBG_00772 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
DOMDFNBG_00773 5.2e-65 tnp L Transposase
DOMDFNBG_00774 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DOMDFNBG_00775 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
DOMDFNBG_00776 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DOMDFNBG_00777 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
DOMDFNBG_00778 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOMDFNBG_00779 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DOMDFNBG_00780 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DOMDFNBG_00781 1.6e-126 IQ reductase
DOMDFNBG_00782 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
DOMDFNBG_00783 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
DOMDFNBG_00784 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOMDFNBG_00785 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOMDFNBG_00786 5.8e-71 marR K Transcriptional regulator, MarR family
DOMDFNBG_00787 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
DOMDFNBG_00788 1.9e-115 S Haloacid dehalogenase-like hydrolase
DOMDFNBG_00789 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
DOMDFNBG_00790 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
DOMDFNBG_00791 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOMDFNBG_00792 2.8e-132 recX 2.4.1.337 GT4 S Regulatory protein RecX
DOMDFNBG_00793 7.8e-102 ygaC J Belongs to the UPF0374 family
DOMDFNBG_00794 6.4e-108 S Domain of unknown function (DUF1803)
DOMDFNBG_00795 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
DOMDFNBG_00798 9.8e-163 L Integrase core domain protein
DOMDFNBG_00799 2.3e-106 L Helix-turn-helix domain
DOMDFNBG_00800 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
DOMDFNBG_00801 3.1e-268 clcA P Chloride transporter, ClC family
DOMDFNBG_00802 8.9e-206 potD P spermidine putrescine ABC transporter
DOMDFNBG_00803 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
DOMDFNBG_00804 1.6e-18 L Integrase core domain
DOMDFNBG_00809 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
DOMDFNBG_00812 4e-133 agrA KT phosphorelay signal transduction system
DOMDFNBG_00813 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
DOMDFNBG_00815 1.6e-236 mesE M Transport protein ComB
DOMDFNBG_00816 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DOMDFNBG_00817 7.4e-62 rplQ J ribosomal protein l17
DOMDFNBG_00818 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOMDFNBG_00819 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DOMDFNBG_00820 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DOMDFNBG_00821 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DOMDFNBG_00822 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DOMDFNBG_00823 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DOMDFNBG_00824 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DOMDFNBG_00825 4.4e-58 rplO J binds to the 23S rRNA
DOMDFNBG_00826 2.5e-23 rpmD J ribosomal protein l30
DOMDFNBG_00827 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOMDFNBG_00828 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DOMDFNBG_00829 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DOMDFNBG_00830 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOMDFNBG_00831 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOMDFNBG_00832 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DOMDFNBG_00833 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOMDFNBG_00834 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DOMDFNBG_00835 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOMDFNBG_00836 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
DOMDFNBG_00837 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DOMDFNBG_00838 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOMDFNBG_00839 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DOMDFNBG_00840 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOMDFNBG_00841 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DOMDFNBG_00842 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DOMDFNBG_00843 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
DOMDFNBG_00844 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOMDFNBG_00845 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
DOMDFNBG_00846 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DOMDFNBG_00847 0.0 XK27_09800 I Acyltransferase
DOMDFNBG_00848 1.7e-35 XK27_09805 S MORN repeat protein
DOMDFNBG_00849 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOMDFNBG_00850 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOMDFNBG_00851 1.5e-89 adk 2.7.4.3 F topology modulation protein
DOMDFNBG_00852 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DOMDFNBG_00853 1.4e-127 Z012_04635 K sequence-specific DNA binding
DOMDFNBG_00855 6.3e-16 C Radical SAM
DOMDFNBG_00856 3.4e-191 C Radical SAM
DOMDFNBG_00857 3.9e-287 V ABC transporter transmembrane region
DOMDFNBG_00858 2.5e-89 K sequence-specific DNA binding
DOMDFNBG_00859 1e-36 L Replication initiation factor
DOMDFNBG_00860 1.6e-106 L Replication initiation factor
DOMDFNBG_00861 1.9e-18 S Domain of unknown function (DUF3173)
DOMDFNBG_00862 1.3e-215 int L Belongs to the 'phage' integrase family
DOMDFNBG_00864 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
DOMDFNBG_00865 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DOMDFNBG_00866 2.8e-44 yrzL S Belongs to the UPF0297 family
DOMDFNBG_00867 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOMDFNBG_00868 4.2e-44 yrzB S Belongs to the UPF0473 family
DOMDFNBG_00869 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
DOMDFNBG_00870 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DOMDFNBG_00871 7.5e-14
DOMDFNBG_00872 2.6e-91 XK27_10930 K acetyltransferase
DOMDFNBG_00873 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DOMDFNBG_00874 7e-147 yaaA S Belongs to the UPF0246 family
DOMDFNBG_00875 9.9e-169 XK27_01785 S cog cog1284
DOMDFNBG_00876 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DOMDFNBG_00878 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
DOMDFNBG_00879 5.7e-52 metE 2.1.1.14 E Methionine synthase
DOMDFNBG_00880 7.6e-64 metE 2.1.1.14 E Methionine synthase
DOMDFNBG_00881 9.2e-36 metE 2.1.1.14 E Methionine synthase
DOMDFNBG_00882 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DOMDFNBG_00883 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DOMDFNBG_00885 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
DOMDFNBG_00886 2.7e-95 S Hydrophobic domain protein
DOMDFNBG_00888 3.7e-27 S Membrane
DOMDFNBG_00889 3.1e-101
DOMDFNBG_00890 1.8e-23 S Small integral membrane protein
DOMDFNBG_00891 1.2e-71 M Protein conserved in bacteria
DOMDFNBG_00892 4.9e-12 K CsbD-like
DOMDFNBG_00893 1e-33 L Transposase
DOMDFNBG_00894 7.6e-22
DOMDFNBG_00895 1.3e-84 K Peptidase S24-like
DOMDFNBG_00896 2.1e-08 K Peptidase S24-like protein
DOMDFNBG_00897 2.3e-55 E IrrE N-terminal-like domain
DOMDFNBG_00898 8e-49 E IrrE N-terminal-like domain
DOMDFNBG_00899 2.4e-92 pat 2.3.1.183 M acetyltransferase
DOMDFNBG_00900 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOMDFNBG_00901 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOMDFNBG_00902 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DOMDFNBG_00903 0.0 smc D Required for chromosome condensation and partitioning
DOMDFNBG_00904 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOMDFNBG_00905 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOMDFNBG_00906 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOMDFNBG_00909 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
DOMDFNBG_00910 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DOMDFNBG_00912 2e-86 S ECF-type riboflavin transporter, S component
DOMDFNBG_00913 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
DOMDFNBG_00914 3.5e-86 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
DOMDFNBG_00915 6.7e-83 XK27_01265 S ECF-type riboflavin transporter, S component
DOMDFNBG_00916 9.5e-294 yfmM S abc transporter atp-binding protein
DOMDFNBG_00917 2.6e-258 noxE P NADH oxidase
DOMDFNBG_00918 7e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DOMDFNBG_00919 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOMDFNBG_00920 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
DOMDFNBG_00921 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
DOMDFNBG_00922 6.9e-165 ypuA S secreted protein
DOMDFNBG_00923 3.6e-61 L Transposase (IS116 IS110 IS902 family)
DOMDFNBG_00924 1.9e-71 L Transposase (IS116 IS110 IS902 family)
DOMDFNBG_00926 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOMDFNBG_00927 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOMDFNBG_00928 8.5e-34 nrdH O Glutaredoxin
DOMDFNBG_00929 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DOMDFNBG_00930 4.3e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
DOMDFNBG_00931 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
DOMDFNBG_00932 7.9e-39 ptsH G phosphocarrier protein Hpr
DOMDFNBG_00933 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOMDFNBG_00934 3.2e-42 L Transposase
DOMDFNBG_00935 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DOMDFNBG_00936 1.1e-12
DOMDFNBG_00937 2.1e-30 rpsT J rRNA binding
DOMDFNBG_00938 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
DOMDFNBG_00939 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
DOMDFNBG_00940 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
DOMDFNBG_00941 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
DOMDFNBG_00942 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DOMDFNBG_00943 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DOMDFNBG_00944 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DOMDFNBG_00945 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
DOMDFNBG_00946 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
DOMDFNBG_00947 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
DOMDFNBG_00948 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
DOMDFNBG_00949 1.2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
DOMDFNBG_00950 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DOMDFNBG_00951 6.8e-81 ypmB S Protein conserved in bacteria
DOMDFNBG_00952 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
DOMDFNBG_00953 2.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
DOMDFNBG_00954 1.5e-07
DOMDFNBG_00956 2.6e-10
DOMDFNBG_00959 1.9e-07
DOMDFNBG_00964 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOMDFNBG_00965 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
DOMDFNBG_00966 5.5e-36 XK27_02060 S Transglycosylase associated protein
DOMDFNBG_00967 2.6e-55 badR K DNA-binding transcription factor activity
DOMDFNBG_00968 3.5e-97 S reductase
DOMDFNBG_00969 3.4e-58 L Integrase core domain protein
DOMDFNBG_00970 0.0 mdlB V abc transporter atp-binding protein
DOMDFNBG_00971 0.0 mdlA V abc transporter atp-binding protein
DOMDFNBG_00973 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
DOMDFNBG_00974 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DOMDFNBG_00975 2.3e-72 yutD J protein conserved in bacteria
DOMDFNBG_00976 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DOMDFNBG_00978 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DOMDFNBG_00979 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOMDFNBG_00980 0.0 ftsI 3.4.16.4 M penicillin-binding protein
DOMDFNBG_00981 8.1e-46 ftsL D cell division protein FtsL
DOMDFNBG_00982 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DOMDFNBG_00983 4.7e-65
DOMDFNBG_00984 2.7e-52
DOMDFNBG_00986 8.7e-33 yhaI J Protein of unknown function (DUF805)
DOMDFNBG_00987 4.5e-18 D nuclear chromosome segregation
DOMDFNBG_00988 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DOMDFNBG_00989 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOMDFNBG_00990 2.2e-285 XK27_00765
DOMDFNBG_00991 8.1e-134 ecsA_2 V abc transporter atp-binding protein
DOMDFNBG_00992 5.2e-125 S Protein of unknown function (DUF554)
DOMDFNBG_00993 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DOMDFNBG_00994 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DOMDFNBG_00995 2.6e-121 liaI S membrane
DOMDFNBG_00996 5.2e-75 XK27_02470 K LytTr DNA-binding domain
DOMDFNBG_00997 3.6e-66 KT response to antibiotic
DOMDFNBG_00998 1.5e-80 yebC M Membrane
DOMDFNBG_00999 2.9e-18 yebC M Membrane
DOMDFNBG_01000 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
DOMDFNBG_01001 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
DOMDFNBG_01003 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOMDFNBG_01004 1.7e-183 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOMDFNBG_01005 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DOMDFNBG_01006 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DOMDFNBG_01007 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DOMDFNBG_01008 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOMDFNBG_01010 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
DOMDFNBG_01011 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
DOMDFNBG_01012 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
DOMDFNBG_01013 5.4e-291 scrB 3.2.1.26 GH32 G invertase
DOMDFNBG_01014 7.5e-180 scrR K Transcriptional
DOMDFNBG_01015 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOMDFNBG_01016 3.4e-62 yqhY S protein conserved in bacteria
DOMDFNBG_01017 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOMDFNBG_01018 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
DOMDFNBG_01019 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
DOMDFNBG_01021 1.3e-08 V 'abc transporter, ATP-binding protein
DOMDFNBG_01022 1.6e-19 V 'abc transporter, ATP-binding protein
DOMDFNBG_01023 2.4e-60 V 'abc transporter, ATP-binding protein
DOMDFNBG_01026 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DOMDFNBG_01027 2e-169 corA P COG0598 Mg2 and Co2 transporters
DOMDFNBG_01028 2.6e-123 XK27_01040 S Pfam PF06570
DOMDFNBG_01030 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOMDFNBG_01031 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DOMDFNBG_01032 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
DOMDFNBG_01033 3.6e-41 XK27_05745
DOMDFNBG_01034 2.5e-230 mutY L A G-specific adenine glycosylase
DOMDFNBG_01039 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOMDFNBG_01040 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DOMDFNBG_01041 1e-93 cvpA S toxin biosynthetic process
DOMDFNBG_01042 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DOMDFNBG_01043 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOMDFNBG_01044 2.6e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DOMDFNBG_01045 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DOMDFNBG_01046 2e-47 azlD E branched-chain amino acid
DOMDFNBG_01047 1.8e-114 azlC E AzlC protein
DOMDFNBG_01048 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOMDFNBG_01049 3.7e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DOMDFNBG_01050 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
DOMDFNBG_01051 2.5e-33 ykzG S Belongs to the UPF0356 family
DOMDFNBG_01052 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOMDFNBG_01053 2.7e-40 pscB M CHAP domain protein
DOMDFNBG_01054 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
DOMDFNBG_01055 8.5e-63 glnR K Transcriptional regulator
DOMDFNBG_01056 1.3e-87 S Fusaric acid resistance protein-like
DOMDFNBG_01057 3e-92 S MucBP domain
DOMDFNBG_01058 1.9e-49 M YSIRK type signal peptide
DOMDFNBG_01059 0.0 M the current gene model (or a revised gene model) may contain a
DOMDFNBG_01061 0.0 mdlB V abc transporter atp-binding protein
DOMDFNBG_01062 0.0 lmrA V abc transporter atp-binding protein
DOMDFNBG_01063 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DOMDFNBG_01064 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DOMDFNBG_01065 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
DOMDFNBG_01066 2.1e-131 rr02 KT response regulator
DOMDFNBG_01067 1.1e-217 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DOMDFNBG_01068 4.8e-168 V ABC transporter
DOMDFNBG_01069 5.4e-122 sagI S ABC-2 type transporter
DOMDFNBG_01070 1e-195 yceA S Belongs to the UPF0176 family
DOMDFNBG_01071 4.3e-22
DOMDFNBG_01072 1.5e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
DOMDFNBG_01073 5.6e-113 S VIT family
DOMDFNBG_01074 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOMDFNBG_01075 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
DOMDFNBG_01076 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
DOMDFNBG_01077 2.2e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
DOMDFNBG_01078 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DOMDFNBG_01079 1.4e-104 GBS0088 J protein conserved in bacteria
DOMDFNBG_01080 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
DOMDFNBG_01081 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DOMDFNBG_01082 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
DOMDFNBG_01083 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DOMDFNBG_01084 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOMDFNBG_01085 8.5e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
DOMDFNBG_01086 2.5e-21
DOMDFNBG_01087 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DOMDFNBG_01089 3.5e-07 U protein secretion
DOMDFNBG_01090 2.7e-50 U protein secretion
DOMDFNBG_01091 4.8e-07 U protein secretion
DOMDFNBG_01092 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
DOMDFNBG_01093 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
DOMDFNBG_01094 4.9e-21 XK27_13030
DOMDFNBG_01095 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOMDFNBG_01096 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DOMDFNBG_01097 9.8e-163 S Protein of unknown function (DUF3114)
DOMDFNBG_01098 1.2e-22 S Protein of unknown function (DUF3114)
DOMDFNBG_01099 1.1e-116 yqfA K protein, Hemolysin III
DOMDFNBG_01100 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
DOMDFNBG_01101 1.7e-218 mvaS 2.3.3.10 I synthase
DOMDFNBG_01102 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DOMDFNBG_01103 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOMDFNBG_01104 9.7e-22
DOMDFNBG_01105 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DOMDFNBG_01106 4.3e-109 engB D Necessary for normal cell division and for the maintenance of normal septation
DOMDFNBG_01107 4.1e-248 mmuP E amino acid
DOMDFNBG_01108 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
DOMDFNBG_01109 1.4e-29 S Domain of unknown function (DUF1912)
DOMDFNBG_01110 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
DOMDFNBG_01111 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DOMDFNBG_01112 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOMDFNBG_01113 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOMDFNBG_01114 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
DOMDFNBG_01115 4.8e-16 S Protein of unknown function (DUF2969)
DOMDFNBG_01118 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
DOMDFNBG_01121 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
DOMDFNBG_01122 6.1e-70 M Pfam SNARE associated Golgi protein
DOMDFNBG_01123 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
DOMDFNBG_01124 9.3e-59 S oxidoreductase
DOMDFNBG_01125 9.7e-66 S oxidoreductase
DOMDFNBG_01126 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
DOMDFNBG_01127 6.7e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
DOMDFNBG_01128 0.0 clpE O Belongs to the ClpA ClpB family
DOMDFNBG_01129 2.6e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOMDFNBG_01130 1.3e-34 ykuJ S protein conserved in bacteria
DOMDFNBG_01131 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
DOMDFNBG_01132 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
DOMDFNBG_01133 3.1e-78 feoA P FeoA domain protein
DOMDFNBG_01134 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DOMDFNBG_01135 1.5e-07
DOMDFNBG_01136 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DOMDFNBG_01137 2.2e-45 K sequence-specific DNA binding
DOMDFNBG_01138 1.5e-35 yugF I carboxylic ester hydrolase activity
DOMDFNBG_01139 7.5e-23 I Alpha/beta hydrolase family
DOMDFNBG_01140 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DOMDFNBG_01141 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOMDFNBG_01142 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
DOMDFNBG_01143 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DOMDFNBG_01145 9.2e-43 licT K transcriptional antiterminator
DOMDFNBG_01146 6.8e-53 licT K transcriptional antiterminator
DOMDFNBG_01147 1.1e-86 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DOMDFNBG_01148 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DOMDFNBG_01149 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOMDFNBG_01150 1.2e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DOMDFNBG_01151 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DOMDFNBG_01152 6e-133 mdtG EGP Major facilitator Superfamily
DOMDFNBG_01153 9.5e-74 mdtG EGP Major facilitator Superfamily
DOMDFNBG_01154 2e-33 secG U Preprotein translocase subunit SecG
DOMDFNBG_01155 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DOMDFNBG_01156 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DOMDFNBG_01157 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOMDFNBG_01158 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
DOMDFNBG_01159 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
DOMDFNBG_01160 4.4e-183 ccpA K Catabolite control protein A
DOMDFNBG_01161 2.8e-28 yyaQ S YjbR
DOMDFNBG_01162 6.6e-101 yyaQ V Protein conserved in bacteria
DOMDFNBG_01163 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DOMDFNBG_01164 1e-78 yueI S Protein of unknown function (DUF1694)
DOMDFNBG_01165 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DOMDFNBG_01166 2e-25 WQ51_00785
DOMDFNBG_01167 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DOMDFNBG_01168 2e-219 ywbD 2.1.1.191 J Methyltransferase
DOMDFNBG_01169 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DOMDFNBG_01170 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DOMDFNBG_01171 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DOMDFNBG_01172 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DOMDFNBG_01173 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
DOMDFNBG_01174 3.2e-53 yheA S Belongs to the UPF0342 family
DOMDFNBG_01175 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DOMDFNBG_01176 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DOMDFNBG_01177 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DOMDFNBG_01178 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
DOMDFNBG_01179 2.6e-253 msrR K Transcriptional regulator
DOMDFNBG_01180 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
DOMDFNBG_01181 2.4e-203 I acyl-CoA dehydrogenase
DOMDFNBG_01182 4.5e-97 mip S hydroperoxide reductase activity
DOMDFNBG_01183 1.3e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOMDFNBG_01184 4.7e-106
DOMDFNBG_01185 1e-31 K Cro/C1-type HTH DNA-binding domain
DOMDFNBG_01186 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
DOMDFNBG_01187 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
DOMDFNBG_01188 1.1e-94
DOMDFNBG_01189 3.1e-195 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DOMDFNBG_01190 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DOMDFNBG_01191 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOMDFNBG_01192 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOMDFNBG_01193 2.6e-194 S CRISPR-associated protein Csn2 subfamily St
DOMDFNBG_01194 2.7e-146 ycgQ S TIGR03943 family
DOMDFNBG_01195 2.1e-155 XK27_03015 S permease
DOMDFNBG_01197 0.0 yhgF K Transcriptional accessory protein
DOMDFNBG_01198 9.9e-42 pspC KT PspC domain
DOMDFNBG_01199 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DOMDFNBG_01200 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOMDFNBG_01202 2.1e-68 ytxH S General stress protein
DOMDFNBG_01204 2e-177 yegQ O Peptidase U32
DOMDFNBG_01205 3.4e-252 yegQ O Peptidase U32
DOMDFNBG_01206 8.1e-46 S CHY zinc finger
DOMDFNBG_01207 8.4e-88 bioY S biotin synthase
DOMDFNBG_01209 1.1e-33 XK27_12190 S protein conserved in bacteria
DOMDFNBG_01210 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
DOMDFNBG_01211 9.6e-12
DOMDFNBG_01212 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
DOMDFNBG_01213 0.0 L helicase
DOMDFNBG_01214 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DOMDFNBG_01215 1e-163 M LysM domain
DOMDFNBG_01216 7.6e-16
DOMDFNBG_01217 7.5e-174 S hydrolase
DOMDFNBG_01218 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
DOMDFNBG_01219 1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DOMDFNBG_01220 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
DOMDFNBG_01221 2.1e-27 P Hemerythrin HHE cation binding domain protein
DOMDFNBG_01222 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DOMDFNBG_01223 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
DOMDFNBG_01224 1.6e-21 MA20_36090 S Protein of unknown function (DUF2974)
DOMDFNBG_01225 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
DOMDFNBG_01226 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
DOMDFNBG_01227 5.9e-134 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
DOMDFNBG_01229 3e-38
DOMDFNBG_01230 1.7e-174 spd F DNA RNA non-specific endonuclease
DOMDFNBG_01231 1.7e-91 lemA S LemA family
DOMDFNBG_01232 9.3e-132 htpX O Belongs to the peptidase M48B family
DOMDFNBG_01233 4.2e-75 S Psort location CytoplasmicMembrane, score
DOMDFNBG_01234 6.2e-56 S Domain of unknown function (DUF4430)
DOMDFNBG_01235 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DOMDFNBG_01236 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
DOMDFNBG_01237 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
DOMDFNBG_01238 2e-188 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
DOMDFNBG_01239 2.2e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DOMDFNBG_01240 3.5e-91 dps P Belongs to the Dps family
DOMDFNBG_01241 1.1e-80 perR P Belongs to the Fur family
DOMDFNBG_01242 8.4e-28 yqgQ S protein conserved in bacteria
DOMDFNBG_01243 2.2e-179 glk 2.7.1.2 G Glucokinase
DOMDFNBG_01244 0.0 typA T GTP-binding protein TypA
DOMDFNBG_01246 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DOMDFNBG_01247 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOMDFNBG_01248 1.1e-171 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DOMDFNBG_01249 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DOMDFNBG_01250 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOMDFNBG_01251 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DOMDFNBG_01252 1.4e-96 sepF D cell septum assembly
DOMDFNBG_01253 2.6e-34 yggT D integral membrane protein
DOMDFNBG_01254 1.2e-143 ylmH T S4 RNA-binding domain
DOMDFNBG_01255 1.8e-135 divIVA D Cell division protein DivIVA
DOMDFNBG_01256 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOMDFNBG_01257 1.4e-212 mntH P Mn2 and Fe2 transporters of the NRAMP family
DOMDFNBG_01258 2e-45 rpmE2 J 50S ribosomal protein L31
DOMDFNBG_01259 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DOMDFNBG_01260 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
DOMDFNBG_01261 3.1e-155 gst O Glutathione S-transferase
DOMDFNBG_01262 2.1e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DOMDFNBG_01263 2.4e-112 tdk 2.7.1.21 F thymidine kinase
DOMDFNBG_01264 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOMDFNBG_01265 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DOMDFNBG_01266 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DOMDFNBG_01267 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DOMDFNBG_01268 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
DOMDFNBG_01269 6.6e-105 pvaA M lytic transglycosylase activity
DOMDFNBG_01270 0.0 yfiB1 V abc transporter atp-binding protein
DOMDFNBG_01271 0.0 XK27_10035 V abc transporter atp-binding protein
DOMDFNBG_01272 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
DOMDFNBG_01273 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOMDFNBG_01274 3.9e-237 dltB M Membrane protein involved in D-alanine export
DOMDFNBG_01275 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOMDFNBG_01276 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DOMDFNBG_01277 1.2e-32 L Integrase core domain protein
DOMDFNBG_01278 8.3e-18 L transposase activity
DOMDFNBG_01279 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOMDFNBG_01280 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DOMDFNBG_01281 1.3e-105 S SseB protein N-terminal domain
DOMDFNBG_01282 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
DOMDFNBG_01283 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOMDFNBG_01284 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DOMDFNBG_01287 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOMDFNBG_01288 3.5e-91 yacP S RNA-binding protein containing a PIN domain
DOMDFNBG_01289 1.7e-154 degV S DegV family
DOMDFNBG_01290 4.7e-32 K helix-turn-helix
DOMDFNBG_01291 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOMDFNBG_01292 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DOMDFNBG_01293 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
DOMDFNBG_01294 9.3e-184 L Phage integrase family
DOMDFNBG_01295 1.7e-22
DOMDFNBG_01296 1.3e-154
DOMDFNBG_01298 1.3e-134 D ftsk spoiiie
DOMDFNBG_01299 5.3e-18 D FtsK/SpoIIIE family
DOMDFNBG_01302 3.7e-226 sthIM 2.1.1.72 L DNA methylase
DOMDFNBG_01303 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
DOMDFNBG_01304 1.9e-86 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
DOMDFNBG_01307 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
DOMDFNBG_01308 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DOMDFNBG_01309 1.1e-83 S Putative small multi-drug export protein
DOMDFNBG_01310 6.2e-76 ctsR K Belongs to the CtsR family
DOMDFNBG_01311 0.0 clpC O Belongs to the ClpA ClpB family
DOMDFNBG_01312 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOMDFNBG_01313 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOMDFNBG_01314 1.2e-165 L integrase core domain
DOMDFNBG_01315 6.7e-122 L Helix-turn-helix domain
DOMDFNBG_01316 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DOMDFNBG_01317 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DOMDFNBG_01318 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DOMDFNBG_01319 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DOMDFNBG_01320 1.1e-142 purR 2.4.2.7 F operon repressor
DOMDFNBG_01321 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
DOMDFNBG_01322 6.9e-173 rmuC S RmuC domain protein
DOMDFNBG_01323 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
DOMDFNBG_01324 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DOMDFNBG_01325 7.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DOMDFNBG_01327 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DOMDFNBG_01328 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DOMDFNBG_01329 4.1e-144 tatD L Hydrolase, tatd
DOMDFNBG_01330 6.1e-73 yccU S CoA-binding protein
DOMDFNBG_01331 4.8e-51 trxA O Belongs to the thioredoxin family
DOMDFNBG_01332 7.8e-143 S Macro domain protein
DOMDFNBG_01333 3.1e-10 L thioesterase
DOMDFNBG_01334 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
DOMDFNBG_01336 1.6e-249 L Transposase
DOMDFNBG_01338 3.6e-88 T PhoQ Sensor
DOMDFNBG_01339 2.2e-43 T PhoQ Sensor
DOMDFNBG_01340 2.8e-40 T PhoQ Sensor
DOMDFNBG_01341 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOMDFNBG_01342 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DOMDFNBG_01343 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
DOMDFNBG_01344 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOMDFNBG_01345 1.7e-94 panT S ECF transporter, substrate-specific component
DOMDFNBG_01346 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
DOMDFNBG_01347 7.3e-166 metF 1.5.1.20 E reductase
DOMDFNBG_01348 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DOMDFNBG_01350 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
DOMDFNBG_01351 0.0 3.6.3.8 P cation transport ATPase
DOMDFNBG_01352 4.5e-19 L transposase and inactivated derivatives, IS30 family
DOMDFNBG_01353 3e-13
DOMDFNBG_01354 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
DOMDFNBG_01355 1.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DOMDFNBG_01356 3.7e-81 queD 4.1.2.50, 4.2.3.12 H synthase
DOMDFNBG_01357 4.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
DOMDFNBG_01358 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
DOMDFNBG_01359 2.2e-19 D nuclear chromosome segregation
DOMDFNBG_01360 2e-135 yejC S cyclic nucleotide-binding protein
DOMDFNBG_01361 1.2e-163 rapZ S Displays ATPase and GTPase activities
DOMDFNBG_01362 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DOMDFNBG_01363 8.7e-162 whiA K May be required for sporulation
DOMDFNBG_01364 2.1e-185 pepD E Dipeptidase
DOMDFNBG_01365 5.4e-32 cspD K Cold shock protein domain
DOMDFNBG_01366 8e-42 K Cold-Shock Protein
DOMDFNBG_01367 0.0 copB 3.6.3.4 P P-type ATPase
DOMDFNBG_01368 9.3e-29 L transposition
DOMDFNBG_01369 5e-17 L Transposase
DOMDFNBG_01378 2.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
DOMDFNBG_01379 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
DOMDFNBG_01380 8.8e-110 6.3.2.2 H ergothioneine biosynthetic process
DOMDFNBG_01382 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
DOMDFNBG_01384 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DOMDFNBG_01385 2.3e-33 L Transposase
DOMDFNBG_01388 5.3e-11
DOMDFNBG_01391 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
DOMDFNBG_01392 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DOMDFNBG_01393 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOMDFNBG_01394 4.4e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
DOMDFNBG_01395 1.1e-151 V MatE
DOMDFNBG_01397 1.5e-109 C Fe-S oxidoreductases
DOMDFNBG_01398 1.2e-176 EGP Major Facilitator Superfamily
DOMDFNBG_01399 5.5e-258 I radical SAM domain protein
DOMDFNBG_01401 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DOMDFNBG_01402 1.4e-150 L Integrase core domain protein
DOMDFNBG_01403 1.8e-87 L transposase activity
DOMDFNBG_01405 2.8e-85
DOMDFNBG_01406 0.0 sbcC L ATPase involved in DNA repair
DOMDFNBG_01407 2e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DOMDFNBG_01408 0.0 lacL 3.2.1.23 G -beta-galactosidase
DOMDFNBG_01409 0.0 lacS G transporter
DOMDFNBG_01410 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DOMDFNBG_01411 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DOMDFNBG_01412 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
DOMDFNBG_01413 1.8e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DOMDFNBG_01414 2.3e-184 galR K Transcriptional regulator
DOMDFNBG_01415 2.7e-08 L Integrase core domain protein
DOMDFNBG_01416 1.2e-25 L transposition
DOMDFNBG_01417 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
DOMDFNBG_01418 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
DOMDFNBG_01419 2.5e-101 V abc transporter atp-binding protein
DOMDFNBG_01420 4.3e-40 V abc transporter atp-binding protein
DOMDFNBG_01421 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
DOMDFNBG_01422 6.4e-62 L Transposase
DOMDFNBG_01423 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOMDFNBG_01424 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOMDFNBG_01425 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOMDFNBG_01426 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DOMDFNBG_01427 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
DOMDFNBG_01428 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DOMDFNBG_01429 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DOMDFNBG_01432 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOMDFNBG_01433 5.8e-175 vraS 2.7.13.3 T Histidine kinase
DOMDFNBG_01434 3.7e-120 yvqF KT membrane
DOMDFNBG_01435 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
DOMDFNBG_01436 2e-132 stp 3.1.3.16 T phosphatase
DOMDFNBG_01437 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DOMDFNBG_01438 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOMDFNBG_01439 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOMDFNBG_01440 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
DOMDFNBG_01441 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DOMDFNBG_01442 6.7e-214 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DOMDFNBG_01443 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
DOMDFNBG_01444 8.2e-148 supH S overlaps another CDS with the same product name
DOMDFNBG_01445 8.6e-63 yvoA_1 K Transcriptional
DOMDFNBG_01446 4.9e-120 skfE V abc transporter atp-binding protein
DOMDFNBG_01447 5.6e-133 V ATPase activity
DOMDFNBG_01448 3.6e-171 oppF P Belongs to the ABC transporter superfamily
DOMDFNBG_01449 6.4e-204 oppD P Belongs to the ABC transporter superfamily
DOMDFNBG_01450 2.4e-167 amiD P ABC transporter (Permease
DOMDFNBG_01451 1.1e-270 amiC P ABC transporter (Permease
DOMDFNBG_01452 0.0 amiA E ABC transporter, substrate-binding protein, family 5
DOMDFNBG_01453 1.2e-24 oppF P Belongs to the ABC transporter superfamily
DOMDFNBG_01454 3.5e-24 oppF P Belongs to the ABC transporter superfamily
DOMDFNBG_01455 8.9e-40 tatD L Hydrolase, tatd
DOMDFNBG_01456 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
DOMDFNBG_01457 3.9e-81 L Integrase core domain protein
DOMDFNBG_01458 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
DOMDFNBG_01459 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
DOMDFNBG_01460 1.2e-155 glcU U Glucose uptake
DOMDFNBG_01461 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
DOMDFNBG_01462 1.2e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
DOMDFNBG_01463 1.3e-88 XK27_10720 D peptidase activity
DOMDFNBG_01464 4e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
DOMDFNBG_01465 1.7e-08
DOMDFNBG_01467 1.1e-170 yeiH S Membrane
DOMDFNBG_01468 3e-117 mur1 NU muramidase
DOMDFNBG_01469 1.6e-19 L transposase activity
DOMDFNBG_01470 8.3e-59 L transposition
DOMDFNBG_01471 4.5e-166 cpsY K Transcriptional regulator
DOMDFNBG_01472 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DOMDFNBG_01473 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
DOMDFNBG_01474 4e-105 artQ P ABC transporter (Permease
DOMDFNBG_01475 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
DOMDFNBG_01476 1.2e-157 aatB ET ABC transporter substrate-binding protein
DOMDFNBG_01477 7.4e-144 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOMDFNBG_01478 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
DOMDFNBG_01479 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
DOMDFNBG_01480 8.8e-21
DOMDFNBG_01481 0.0 res_1 3.1.21.5 S Type III restriction
DOMDFNBG_01482 0.0 M family 8
DOMDFNBG_01483 2.7e-09
DOMDFNBG_01484 5.8e-109 MA20_06410 E LysE type translocator
DOMDFNBG_01485 2.7e-26 IQ PFAM AMP-dependent synthetase and ligase
DOMDFNBG_01486 3.3e-24 IQ PFAM AMP-dependent synthetase and ligase
DOMDFNBG_01487 4e-20
DOMDFNBG_01488 1.9e-35
DOMDFNBG_01489 1.3e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOMDFNBG_01490 1.6e-58
DOMDFNBG_01492 7.4e-31 S Signal peptide protein, YSIRK family
DOMDFNBG_01493 1.8e-54 K response regulator
DOMDFNBG_01494 1.1e-37 BP1961 P nitric oxide dioxygenase activity
DOMDFNBG_01496 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
DOMDFNBG_01497 1e-181 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DOMDFNBG_01498 1.5e-160 yvgN C reductase
DOMDFNBG_01499 4.2e-96 yoaK S Protein of unknown function (DUF1275)
DOMDFNBG_01500 2.2e-111 drgA C Nitroreductase
DOMDFNBG_01501 1.1e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOMDFNBG_01502 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
DOMDFNBG_01503 5.6e-77 ywnA K Transcriptional regulator
DOMDFNBG_01504 1.2e-138 1.13.11.2 S glyoxalase
DOMDFNBG_01505 5.7e-109 XK27_02070 S nitroreductase
DOMDFNBG_01506 6.2e-228 yfnA E amino acid
DOMDFNBG_01507 4.8e-25 csbD K CsbD-like
DOMDFNBG_01508 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
DOMDFNBG_01509 1.9e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
DOMDFNBG_01510 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
DOMDFNBG_01511 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOMDFNBG_01512 4.5e-247 norM V Multidrug efflux pump
DOMDFNBG_01513 9.2e-119 pbuX F xanthine permease
DOMDFNBG_01514 3.3e-69 pbuX F xanthine permease
DOMDFNBG_01515 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DOMDFNBG_01516 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOMDFNBG_01517 9e-165 T Histidine kinase
DOMDFNBG_01518 1.9e-133 macB2 V ABC transporter, ATP-binding protein
DOMDFNBG_01519 0.0 V ABC transporter (permease)
DOMDFNBG_01520 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
DOMDFNBG_01521 2.6e-30 liaI KT membrane
DOMDFNBG_01522 1.4e-15 liaI KT membrane
DOMDFNBG_01523 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
DOMDFNBG_01524 3.7e-122 S An automated process has identified a potential problem with this gene model
DOMDFNBG_01526 4.6e-42 3.6.1.55 F NUDIX domain
DOMDFNBG_01527 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
DOMDFNBG_01528 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
DOMDFNBG_01529 6.6e-213 EGP Major facilitator Superfamily
DOMDFNBG_01533 5.3e-156 XK27_09825 V abc transporter atp-binding protein
DOMDFNBG_01534 1.2e-132 yvfS V ABC-2 type transporter
DOMDFNBG_01535 1.5e-184 desK 2.7.13.3 T Histidine kinase
DOMDFNBG_01536 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DOMDFNBG_01537 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
DOMDFNBG_01538 2.5e-308 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DOMDFNBG_01539 1.6e-205 S Protein of unknown function (DUF917)
DOMDFNBG_01540 2.5e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
DOMDFNBG_01541 2.3e-103 proWZ P ABC transporter (Permease
DOMDFNBG_01542 3.8e-165 proX M ABC transporter, substrate-binding protein, QAT family
DOMDFNBG_01543 1.6e-137 proV E abc transporter atp-binding protein
DOMDFNBG_01544 2e-88 proW P Binding-protein-dependent transport system inner membrane component
DOMDFNBG_01545 1.2e-62 bioY S biotin transmembrane transporter activity
DOMDFNBG_01546 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
DOMDFNBG_01547 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DOMDFNBG_01548 3.4e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOMDFNBG_01549 3e-27 L Integrase core domain protein
DOMDFNBG_01550 1.2e-34
DOMDFNBG_01551 4.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DOMDFNBG_01552 5.2e-167 dnaI L Primosomal protein DnaI
DOMDFNBG_01553 6.5e-218 dnaB L Replication initiation and membrane attachment
DOMDFNBG_01554 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DOMDFNBG_01555 2.8e-282 T PhoQ Sensor
DOMDFNBG_01556 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DOMDFNBG_01557 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
DOMDFNBG_01558 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
DOMDFNBG_01559 3.4e-242 P COG0168 Trk-type K transport systems, membrane components
DOMDFNBG_01560 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
DOMDFNBG_01561 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
DOMDFNBG_01562 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DOMDFNBG_01563 1.2e-149 cbiQ P cobalt transport
DOMDFNBG_01564 0.0 ykoD P abc transporter atp-binding protein
DOMDFNBG_01565 8e-94 S UPF0397 protein
DOMDFNBG_01566 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
DOMDFNBG_01567 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DOMDFNBG_01568 5.2e-98 metI P ABC transporter (Permease
DOMDFNBG_01569 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOMDFNBG_01570 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
DOMDFNBG_01571 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
DOMDFNBG_01572 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
DOMDFNBG_01573 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
DOMDFNBG_01574 4.5e-152 ET amino acid transport
DOMDFNBG_01575 1.6e-131 cbiO P ABC transporter
DOMDFNBG_01576 1.1e-136 P cobalt transport protein
DOMDFNBG_01577 2.7e-177 cbiM P PDGLE domain
DOMDFNBG_01578 4.9e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DOMDFNBG_01579 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DOMDFNBG_01580 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DOMDFNBG_01581 6.6e-78 ureE O enzyme active site formation
DOMDFNBG_01582 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
DOMDFNBG_01583 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
DOMDFNBG_01584 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
DOMDFNBG_01585 6.8e-95 ureI S AmiS/UreI family transporter
DOMDFNBG_01586 9.2e-132 S Domain of unknown function (DUF4173)
DOMDFNBG_01587 6.7e-36 S Domain of unknown function (DUF4173)
DOMDFNBG_01588 3.7e-51 yhaI L Membrane
DOMDFNBG_01589 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DOMDFNBG_01590 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DOMDFNBG_01591 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DOMDFNBG_01592 1.9e-33 V protein secretion by the type I secretion system
DOMDFNBG_01593 1.6e-160 K sequence-specific DNA binding
DOMDFNBG_01594 7e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
DOMDFNBG_01595 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DOMDFNBG_01596 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DOMDFNBG_01597 1.3e-246 trkA P Potassium transporter peripheral membrane component
DOMDFNBG_01598 1.2e-258 trkH P Cation transport protein
DOMDFNBG_01599 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DOMDFNBG_01600 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOMDFNBG_01601 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DOMDFNBG_01602 9e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DOMDFNBG_01603 1.1e-136 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
DOMDFNBG_01604 7.8e-85 ykuL S CBS domain
DOMDFNBG_01605 3.5e-99 XK27_09740 S Phosphoesterase
DOMDFNBG_01606 1.3e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOMDFNBG_01607 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DOMDFNBG_01608 7.6e-36 yneF S UPF0154 protein
DOMDFNBG_01609 3.7e-91 K transcriptional regulator
DOMDFNBG_01610 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DOMDFNBG_01613 8.8e-98 ybhL S Belongs to the BI1 family
DOMDFNBG_01614 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
DOMDFNBG_01615 2.5e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOMDFNBG_01616 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DOMDFNBG_01617 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOMDFNBG_01618 5.2e-59 L Integrase core domain protein
DOMDFNBG_01619 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOMDFNBG_01620 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DOMDFNBG_01621 7.3e-80 XK27_09675 K -acetyltransferase
DOMDFNBG_01622 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DOMDFNBG_01623 2.5e-23
DOMDFNBG_01624 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
DOMDFNBG_01625 1.1e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
DOMDFNBG_01626 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DOMDFNBG_01627 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DOMDFNBG_01628 3.1e-95 ypsA S Belongs to the UPF0398 family
DOMDFNBG_01629 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DOMDFNBG_01630 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DOMDFNBG_01631 4.6e-260 pepC 3.4.22.40 E aminopeptidase
DOMDFNBG_01632 1.9e-77 yhaI L Membrane
DOMDFNBG_01633 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DOMDFNBG_01634 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOMDFNBG_01635 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
DOMDFNBG_01636 2.6e-76 S thiolester hydrolase activity
DOMDFNBG_01638 3.8e-40 K transcriptional
DOMDFNBG_01639 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOMDFNBG_01640 3.1e-136 glcR K transcriptional regulator (DeoR family)
DOMDFNBG_01641 1.1e-34 cof Q phosphatase activity
DOMDFNBG_01642 6e-55 cof Q phosphatase activity
DOMDFNBG_01643 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
DOMDFNBG_01644 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
DOMDFNBG_01645 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
DOMDFNBG_01646 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DOMDFNBG_01647 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOMDFNBG_01648 9.9e-55 S TM2 domain
DOMDFNBG_01649 4.7e-43
DOMDFNBG_01652 1.9e-17 L transposase activity
DOMDFNBG_01653 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DOMDFNBG_01654 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DOMDFNBG_01655 5.2e-142 cmpC S abc transporter atp-binding protein
DOMDFNBG_01656 0.0 WQ51_06230 S ABC transporter substrate binding protein
DOMDFNBG_01657 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DOMDFNBG_01658 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DOMDFNBG_01659 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
DOMDFNBG_01660 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOMDFNBG_01661 9.8e-50 yajC U protein transport
DOMDFNBG_01662 1.9e-127 yeeN K transcriptional regulatory protein
DOMDFNBG_01663 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
DOMDFNBG_01664 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
DOMDFNBG_01665 1.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DOMDFNBG_01666 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
DOMDFNBG_01667 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
DOMDFNBG_01668 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
DOMDFNBG_01669 2.5e-128 adcB P ABC transporter (Permease
DOMDFNBG_01670 6.4e-136 adcC P ABC transporter, ATP-binding protein
DOMDFNBG_01671 3.1e-72 adcR K transcriptional
DOMDFNBG_01672 1.9e-223 EGP Major facilitator Superfamily
DOMDFNBG_01673 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOMDFNBG_01674 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DOMDFNBG_01677 9e-170 oppF P Belongs to the ABC transporter superfamily
DOMDFNBG_01678 3.1e-43 oppD P Belongs to the ABC transporter superfamily
DOMDFNBG_01679 1.7e-61 oppD P Belongs to the ABC transporter superfamily
DOMDFNBG_01680 2.5e-32 oppD P Belongs to the ABC transporter superfamily
DOMDFNBG_01681 3e-27 oppD P Belongs to the ABC transporter superfamily
DOMDFNBG_01682 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOMDFNBG_01683 7.3e-74 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOMDFNBG_01684 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOMDFNBG_01685 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOMDFNBG_01686 2e-138 oppA E ABC transporter substrate-binding protein
DOMDFNBG_01687 7e-10 oppA E ABC transporter substrate-binding protein
DOMDFNBG_01688 3.5e-274 sufB O assembly protein SufB
DOMDFNBG_01689 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
DOMDFNBG_01690 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOMDFNBG_01691 6.3e-235 sufD O assembly protein SufD
DOMDFNBG_01692 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
DOMDFNBG_01693 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
DOMDFNBG_01694 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DOMDFNBG_01695 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DOMDFNBG_01696 1.8e-276 glnP P ABC transporter
DOMDFNBG_01697 1e-123 glnQ E abc transporter atp-binding protein
DOMDFNBG_01699 5e-94 V VanZ like family
DOMDFNBG_01700 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DOMDFNBG_01701 6.5e-202 yhjX P Major Facilitator
DOMDFNBG_01702 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
DOMDFNBG_01703 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DOMDFNBG_01704 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DOMDFNBG_01705 1.9e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DOMDFNBG_01706 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DOMDFNBG_01707 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DOMDFNBG_01708 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DOMDFNBG_01709 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DOMDFNBG_01710 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOMDFNBG_01711 2.4e-83 nrdI F Belongs to the NrdI family
DOMDFNBG_01712 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
DOMDFNBG_01713 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DOMDFNBG_01714 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
DOMDFNBG_01715 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
DOMDFNBG_01716 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
DOMDFNBG_01717 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DOMDFNBG_01718 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DOMDFNBG_01719 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DOMDFNBG_01720 6.6e-148 ykuT M mechanosensitive ion channel
DOMDFNBG_01721 1.6e-77 sigH K DNA-templated transcription, initiation
DOMDFNBG_01722 6.5e-87
DOMDFNBG_01723 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DOMDFNBG_01724 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
DOMDFNBG_01725 9.9e-19 S Domain of unknown function (DUF4649)
DOMDFNBG_01726 1.7e-162 L Transposase
DOMDFNBG_01727 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOMDFNBG_01728 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DOMDFNBG_01729 7.2e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DOMDFNBG_01730 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
DOMDFNBG_01732 3.5e-61 divIC D Septum formation initiator
DOMDFNBG_01733 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
DOMDFNBG_01734 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOMDFNBG_01735 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DOMDFNBG_01736 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DOMDFNBG_01737 1.1e-29 yyzM S Protein conserved in bacteria
DOMDFNBG_01738 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DOMDFNBG_01739 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOMDFNBG_01740 8.5e-134 parB K Belongs to the ParB family
DOMDFNBG_01741 5.3e-194 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
DOMDFNBG_01742 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOMDFNBG_01743 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
DOMDFNBG_01747 0.0 XK27_10405 S Bacterial membrane protein YfhO
DOMDFNBG_01748 6.7e-306 ybiT S abc transporter atp-binding protein
DOMDFNBG_01749 5.4e-153 yvjA S membrane
DOMDFNBG_01750 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
DOMDFNBG_01751 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DOMDFNBG_01752 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DOMDFNBG_01753 2.3e-44 yaaA S S4 domain protein YaaA
DOMDFNBG_01754 1.1e-234 ymfF S Peptidase M16
DOMDFNBG_01755 3.1e-242 ymfH S Peptidase M16
DOMDFNBG_01756 6.3e-138 ymfM S sequence-specific DNA binding
DOMDFNBG_01757 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOMDFNBG_01758 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOMDFNBG_01759 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOMDFNBG_01760 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOMDFNBG_01761 5.3e-85 lytE M LysM domain protein
DOMDFNBG_01762 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
DOMDFNBG_01763 0.0 S Bacterial membrane protein, YfhO
DOMDFNBG_01764 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DOMDFNBG_01765 1.5e-77 F NUDIX domain
DOMDFNBG_01766 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DOMDFNBG_01767 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DOMDFNBG_01768 3.9e-70 rplI J binds to the 23S rRNA
DOMDFNBG_01769 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DOMDFNBG_01770 8.2e-48 veg S Biofilm formation stimulator VEG
DOMDFNBG_01771 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DOMDFNBG_01772 2.7e-08
DOMDFNBG_01773 4.8e-55 ypaA M Membrane
DOMDFNBG_01774 1.6e-94 XK27_06935 K transcriptional regulator
DOMDFNBG_01775 3.9e-161 XK27_06930 V domain protein
DOMDFNBG_01776 4.8e-106 S Putative adhesin
DOMDFNBG_01777 4.3e-61 L COG2801 Transposase and inactivated derivatives
DOMDFNBG_01778 1e-45 M Glycosyltransferase family 92
DOMDFNBG_01779 8.1e-154 L COG2801 Transposase and inactivated derivatives
DOMDFNBG_01780 2.3e-38 L transposase activity
DOMDFNBG_01781 1e-13 rpmH J Ribosomal protein L34
DOMDFNBG_01782 2e-186 jag S RNA-binding protein
DOMDFNBG_01783 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOMDFNBG_01784 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DOMDFNBG_01785 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
DOMDFNBG_01786 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DOMDFNBG_01787 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOMDFNBG_01788 7.4e-80 amiA E transmembrane transport
DOMDFNBG_01789 7.3e-69 amiA E transmembrane transport
DOMDFNBG_01790 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DOMDFNBG_01791 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DOMDFNBG_01792 9.2e-51 S Protein of unknown function (DUF3397)
DOMDFNBG_01793 2.3e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DOMDFNBG_01794 1.1e-57 WQ51_05710 S Mitochondrial biogenesis AIM24
DOMDFNBG_01795 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
DOMDFNBG_01796 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DOMDFNBG_01797 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DOMDFNBG_01798 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
DOMDFNBG_01799 4.3e-77 XK27_09620 S reductase
DOMDFNBG_01800 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
DOMDFNBG_01801 3.1e-115 XK27_09615 C reductase
DOMDFNBG_01802 1.6e-61 fnt P Formate nitrite transporter
DOMDFNBG_01803 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
DOMDFNBG_01804 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DOMDFNBG_01805 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DOMDFNBG_01806 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
DOMDFNBG_01807 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOMDFNBG_01808 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DOMDFNBG_01809 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DOMDFNBG_01810 2.7e-48 S glycolate biosynthetic process
DOMDFNBG_01811 3.4e-64 S phosphatase activity
DOMDFNBG_01812 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
DOMDFNBG_01815 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DOMDFNBG_01816 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DOMDFNBG_01817 4.1e-36 yeeD O sulfur carrier activity
DOMDFNBG_01818 1.3e-190 yeeE S Sulphur transport
DOMDFNBG_01819 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOMDFNBG_01820 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DOMDFNBG_01821 4.1e-09 S Domain of unknown function (DUF4651)
DOMDFNBG_01822 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
DOMDFNBG_01823 1.5e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOMDFNBG_01824 1.8e-111 S CAAX amino terminal protease family protein
DOMDFNBG_01826 5e-67 V CAAX protease self-immunity
DOMDFNBG_01827 1.4e-33 V CAAX protease self-immunity
DOMDFNBG_01829 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOMDFNBG_01830 5.9e-177 ytxK 2.1.1.72 L DNA methylase
DOMDFNBG_01831 2e-12 comGF U Putative Competence protein ComGF
DOMDFNBG_01832 1.5e-71 comGF U Competence protein ComGF
DOMDFNBG_01833 1.4e-15 NU Type II secretory pathway pseudopilin
DOMDFNBG_01834 1.8e-57 cglD NU Competence protein
DOMDFNBG_01835 8.5e-43 comGC U Required for transformation and DNA binding
DOMDFNBG_01836 3e-145 cglB NU type II secretion system
DOMDFNBG_01837 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DOMDFNBG_01838 2.9e-68 S cog cog4699
DOMDFNBG_01839 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOMDFNBG_01840 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOMDFNBG_01841 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DOMDFNBG_01842 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOMDFNBG_01843 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DOMDFNBG_01844 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
DOMDFNBG_01845 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
DOMDFNBG_01846 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DOMDFNBG_01847 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DOMDFNBG_01848 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
DOMDFNBG_01849 1.4e-57 asp S cog cog1302
DOMDFNBG_01850 9.3e-226 norN V Mate efflux family protein
DOMDFNBG_01851 2.4e-278 thrC 4.2.3.1 E Threonine synthase
DOMDFNBG_01852 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DOMDFNBG_01853 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
DOMDFNBG_01854 3.3e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DOMDFNBG_01855 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DOMDFNBG_01856 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
DOMDFNBG_01857 0.0 pepO 3.4.24.71 O Peptidase family M13
DOMDFNBG_01858 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DOMDFNBG_01859 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DOMDFNBG_01860 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DOMDFNBG_01861 1.4e-54 treB 2.7.1.201 G PTS System
DOMDFNBG_01862 5.8e-21 treR K DNA-binding transcription factor activity
DOMDFNBG_01863 1.2e-85 treR K trehalose operon
DOMDFNBG_01864 3.3e-95 ywlG S Belongs to the UPF0340 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)