ORF_ID e_value Gene_name EC_number CAZy COGs Description
HPBIMMBF_00001 1.9e-136 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HPBIMMBF_00002 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HPBIMMBF_00003 6.5e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HPBIMMBF_00004 5.5e-93 S SdpI/YhfL protein family
HPBIMMBF_00005 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPBIMMBF_00006 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HPBIMMBF_00007 3.9e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPBIMMBF_00008 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPBIMMBF_00009 2.1e-63 yodB K Transcriptional regulator, HxlR family
HPBIMMBF_00010 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPBIMMBF_00011 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPBIMMBF_00012 1.1e-185 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPBIMMBF_00013 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
HPBIMMBF_00014 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPBIMMBF_00015 8.6e-96 liaI S membrane
HPBIMMBF_00016 1.3e-73 XK27_02470 K LytTr DNA-binding domain
HPBIMMBF_00017 1.5e-54 yneR S Belongs to the HesB IscA family
HPBIMMBF_00018 0.0 S membrane
HPBIMMBF_00019 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HPBIMMBF_00020 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPBIMMBF_00021 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPBIMMBF_00022 3.3e-113 gluP 3.4.21.105 S Peptidase, S54 family
HPBIMMBF_00023 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HPBIMMBF_00024 5.7e-180 glk 2.7.1.2 G Glucokinase
HPBIMMBF_00025 1.9e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
HPBIMMBF_00026 4.4e-68 yqhL P Rhodanese-like protein
HPBIMMBF_00027 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HPBIMMBF_00028 1.4e-138 glpQ 3.1.4.46 C phosphodiesterase
HPBIMMBF_00029 9.2e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPBIMMBF_00030 4.6e-64 glnR K Transcriptional regulator
HPBIMMBF_00031 9e-264 glnA 6.3.1.2 E glutamine synthetase
HPBIMMBF_00032 6.9e-162
HPBIMMBF_00033 8.8e-181
HPBIMMBF_00034 3.1e-98 dut S Protein conserved in bacteria
HPBIMMBF_00035 5.3e-56
HPBIMMBF_00036 8.7e-30
HPBIMMBF_00039 5.4e-19
HPBIMMBF_00040 1.8e-89 K Transcriptional regulator
HPBIMMBF_00041 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HPBIMMBF_00042 3.5e-52 ysxB J Cysteine protease Prp
HPBIMMBF_00043 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HPBIMMBF_00044 1.7e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPBIMMBF_00045 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPBIMMBF_00046 3.5e-74 yqhY S Asp23 family, cell envelope-related function
HPBIMMBF_00047 5.8e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPBIMMBF_00048 1.1e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPBIMMBF_00049 3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPBIMMBF_00050 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPBIMMBF_00051 1e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPBIMMBF_00052 2.6e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HPBIMMBF_00053 7.4e-77 argR K Regulates arginine biosynthesis genes
HPBIMMBF_00054 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
HPBIMMBF_00055 1.3e-221 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
HPBIMMBF_00056 1.2e-104 opuCB E ABC transporter permease
HPBIMMBF_00057 1.7e-173 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPBIMMBF_00058 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
HPBIMMBF_00059 4.5e-55
HPBIMMBF_00060 9.6e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HPBIMMBF_00061 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPBIMMBF_00062 2e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPBIMMBF_00063 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPBIMMBF_00064 4.2e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPBIMMBF_00065 2.7e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPBIMMBF_00066 4.1e-133 stp 3.1.3.16 T phosphatase
HPBIMMBF_00067 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HPBIMMBF_00068 7e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPBIMMBF_00069 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HPBIMMBF_00070 5.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HPBIMMBF_00071 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HPBIMMBF_00072 1.8e-57 asp S Asp23 family, cell envelope-related function
HPBIMMBF_00073 0.0 yloV S DAK2 domain fusion protein YloV
HPBIMMBF_00074 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPBIMMBF_00075 1.5e-186 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPBIMMBF_00076 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPBIMMBF_00077 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPBIMMBF_00078 0.0 smc D Required for chromosome condensation and partitioning
HPBIMMBF_00079 7.3e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPBIMMBF_00080 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPBIMMBF_00081 1.6e-218 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPBIMMBF_00082 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HPBIMMBF_00083 2.6e-39 ylqC S Belongs to the UPF0109 family
HPBIMMBF_00084 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPBIMMBF_00085 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HPBIMMBF_00086 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPBIMMBF_00087 1.6e-49
HPBIMMBF_00088 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HPBIMMBF_00089 1.4e-86
HPBIMMBF_00090 8.2e-137 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HPBIMMBF_00091 3.6e-272 XK27_00765
HPBIMMBF_00093 1.2e-269 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
HPBIMMBF_00094 1e-102 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
HPBIMMBF_00095 1e-166 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPBIMMBF_00096 1.4e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HPBIMMBF_00097 1.6e-109 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HPBIMMBF_00098 2.3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPBIMMBF_00099 3.3e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPBIMMBF_00100 4.2e-95 entB 3.5.1.19 Q Isochorismatase family
HPBIMMBF_00101 5.9e-177 1.6.5.5 C Zinc-binding dehydrogenase
HPBIMMBF_00102 1.2e-67 ybbJ K Acetyltransferase (GNAT) family
HPBIMMBF_00103 8.9e-60 E glutamate:sodium symporter activity
HPBIMMBF_00104 1.4e-148 E glutamate:sodium symporter activity
HPBIMMBF_00105 1.6e-213 3.5.1.47 E Peptidase family M20/M25/M40
HPBIMMBF_00106 2.7e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HPBIMMBF_00107 5.5e-59 S Protein of unknown function (DUF1648)
HPBIMMBF_00108 1.2e-143 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPBIMMBF_00109 1.9e-15 yneE K Transcriptional regulator
HPBIMMBF_00110 2.9e-151 yneE K Transcriptional regulator
HPBIMMBF_00111 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HPBIMMBF_00112 2.5e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPBIMMBF_00113 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPBIMMBF_00114 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HPBIMMBF_00115 4.7e-126 IQ reductase
HPBIMMBF_00116 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPBIMMBF_00117 3.8e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPBIMMBF_00118 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HPBIMMBF_00119 3.1e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HPBIMMBF_00120 6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPBIMMBF_00121 2.6e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HPBIMMBF_00122 2.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HPBIMMBF_00123 4.9e-99 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HPBIMMBF_00124 1.3e-123 S Protein of unknown function (DUF554)
HPBIMMBF_00125 1e-159 K LysR substrate binding domain
HPBIMMBF_00126 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
HPBIMMBF_00127 1.7e-146 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPBIMMBF_00128 2.3e-93 K transcriptional regulator
HPBIMMBF_00129 4.6e-297 norB EGP Major Facilitator
HPBIMMBF_00130 3.4e-139 f42a O Band 7 protein
HPBIMMBF_00131 1.1e-86 S Protein of unknown function with HXXEE motif
HPBIMMBF_00132 9.2e-13 K Bacterial regulatory proteins, tetR family
HPBIMMBF_00133 5.4e-48 L Integrase core domain
HPBIMMBF_00134 2.9e-78 3.6.1.55 F NUDIX domain
HPBIMMBF_00135 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPBIMMBF_00136 1.6e-97 K Bacterial regulatory proteins, tetR family
HPBIMMBF_00137 8.4e-85 S membrane transporter protein
HPBIMMBF_00138 1.7e-207 EGP Major facilitator Superfamily
HPBIMMBF_00139 2e-71 K MarR family
HPBIMMBF_00140 3.1e-148 XK27_00825 S Sulfite exporter TauE/SafE
HPBIMMBF_00141 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
HPBIMMBF_00142 1e-243 steT E amino acid
HPBIMMBF_00143 4.9e-142 G YdjC-like protein
HPBIMMBF_00144 2.2e-255 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HPBIMMBF_00145 2.1e-154 K CAT RNA binding domain
HPBIMMBF_00146 1.5e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPBIMMBF_00147 4e-108 glnP P ABC transporter permease
HPBIMMBF_00148 1.6e-109 gluC P ABC transporter permease
HPBIMMBF_00149 7.8e-149 glnH ET ABC transporter substrate-binding protein
HPBIMMBF_00150 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPBIMMBF_00152 3.6e-41
HPBIMMBF_00153 1.6e-169 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPBIMMBF_00154 6.6e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HPBIMMBF_00155 4.4e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HPBIMMBF_00157 1.8e-137
HPBIMMBF_00158 7.2e-12 3.2.1.14 GH18
HPBIMMBF_00159 1.3e-81 zur P Belongs to the Fur family
HPBIMMBF_00160 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
HPBIMMBF_00161 1.8e-19
HPBIMMBF_00162 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HPBIMMBF_00163 3.5e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HPBIMMBF_00164 1.3e-87
HPBIMMBF_00165 3.1e-251 yfnA E Amino Acid
HPBIMMBF_00166 2.6e-46
HPBIMMBF_00167 5e-69 O OsmC-like protein
HPBIMMBF_00168 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPBIMMBF_00169 0.0 oatA I Acyltransferase
HPBIMMBF_00170 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPBIMMBF_00171 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HPBIMMBF_00172 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPBIMMBF_00173 4.5e-152 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HPBIMMBF_00174 7.7e-91 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPBIMMBF_00175 1.7e-226 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPBIMMBF_00176 1.2e-225 pbuG S permease
HPBIMMBF_00177 1.5e-19
HPBIMMBF_00178 1.3e-82 K Transcriptional regulator
HPBIMMBF_00179 2.5e-152 licD M LicD family
HPBIMMBF_00180 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HPBIMMBF_00181 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPBIMMBF_00182 5.5e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HPBIMMBF_00183 2.4e-238 EGP Major facilitator Superfamily
HPBIMMBF_00184 4.2e-89 V VanZ like family
HPBIMMBF_00185 1.9e-33
HPBIMMBF_00186 1.9e-71 spxA 1.20.4.1 P ArsC family
HPBIMMBF_00188 3e-122
HPBIMMBF_00189 3.8e-273 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPBIMMBF_00190 2.3e-13 G Transmembrane secretion effector
HPBIMMBF_00191 6.5e-136 EGP Transmembrane secretion effector
HPBIMMBF_00192 1.9e-130 1.5.1.39 C nitroreductase
HPBIMMBF_00193 3.3e-71
HPBIMMBF_00194 1.5e-52
HPBIMMBF_00195 6e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPBIMMBF_00196 8.5e-102 K Bacterial regulatory proteins, tetR family
HPBIMMBF_00197 5.1e-145 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HPBIMMBF_00198 6.4e-93 yliE T EAL domain
HPBIMMBF_00199 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPBIMMBF_00200 4.7e-39 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00201 1.5e-152 mccF 3.4.17.13 V LD-carboxypeptidase
HPBIMMBF_00202 7.1e-237 M hydrolase, family 25
HPBIMMBF_00203 1.4e-76 K Acetyltransferase (GNAT) domain
HPBIMMBF_00204 8.1e-207 mccF V LD-carboxypeptidase
HPBIMMBF_00205 8.2e-125 M Glycosyltransferase, group 2 family protein
HPBIMMBF_00206 1.1e-16 mobC S Bacterial mobilisation protein (MobC)
HPBIMMBF_00207 5e-97 D Relaxase/Mobilisation nuclease domain
HPBIMMBF_00208 9e-79
HPBIMMBF_00209 3.5e-118 L Initiator Replication protein
HPBIMMBF_00211 1.4e-170 L Initiator Replication protein
HPBIMMBF_00212 3.5e-27
HPBIMMBF_00213 4.4e-27 S Protein of unknown function (DUF1093)
HPBIMMBF_00214 6.2e-42
HPBIMMBF_00215 5.5e-22 L Initiator Replication protein
HPBIMMBF_00216 1.3e-74 L Initiator Replication protein
HPBIMMBF_00217 2.5e-99 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HPBIMMBF_00220 1.2e-33
HPBIMMBF_00232 5.5e-08
HPBIMMBF_00242 4.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HPBIMMBF_00243 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
HPBIMMBF_00244 1.9e-43 relB L Addiction module antitoxin, RelB DinJ family
HPBIMMBF_00245 1.1e-52 repA S Replication initiator protein A
HPBIMMBF_00246 3.2e-36 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPBIMMBF_00247 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HPBIMMBF_00248 1.2e-23 S Family of unknown function (DUF5388)
HPBIMMBF_00249 8.1e-97 K Bacterial regulatory proteins, tetR family
HPBIMMBF_00250 7.3e-133 D CobQ CobB MinD ParA nucleotide binding domain protein
HPBIMMBF_00252 3.6e-130 repA S Replication initiator protein A
HPBIMMBF_00253 4.4e-95 tnpR1 L Resolvase, N terminal domain
HPBIMMBF_00254 8.2e-137 ywqE 3.1.3.48 GM PHP domain protein
HPBIMMBF_00255 5.4e-130 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HPBIMMBF_00256 3.9e-70 epsB M biosynthesis protein
HPBIMMBF_00257 4e-37
HPBIMMBF_00259 2.3e-34
HPBIMMBF_00260 4.9e-145 soj D AAA domain
HPBIMMBF_00261 1e-24
HPBIMMBF_00262 4.2e-49
HPBIMMBF_00263 9.4e-65 ycgX S Protein of unknown function (DUF1398)
HPBIMMBF_00264 4e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HPBIMMBF_00265 1.9e-80 mdtG EGP Major facilitator Superfamily
HPBIMMBF_00267 3.2e-63 S DNA binding
HPBIMMBF_00272 2.8e-18
HPBIMMBF_00274 1.3e-143 S Protein of unknown function (DUF1351)
HPBIMMBF_00275 4e-116 S AAA domain
HPBIMMBF_00276 2.4e-92 S Protein of unknown function (DUF669)
HPBIMMBF_00277 7.9e-131 S Putative HNHc nuclease
HPBIMMBF_00278 1.7e-54 L DnaD domain protein
HPBIMMBF_00279 1.9e-144 pi346 L IstB-like ATP binding protein
HPBIMMBF_00281 3.2e-59
HPBIMMBF_00282 2.7e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HPBIMMBF_00287 1.7e-26 S YopX protein
HPBIMMBF_00288 8.9e-35
HPBIMMBF_00289 8.2e-65 S Transcriptional regulator, RinA family
HPBIMMBF_00292 2.4e-12 V HNH nucleases
HPBIMMBF_00293 8.6e-90 L HNH nucleases
HPBIMMBF_00294 1.6e-76 L Phage terminase, small subunit
HPBIMMBF_00295 1.1e-96 S Phage Terminase
HPBIMMBF_00296 2e-244 S Phage Terminase
HPBIMMBF_00297 3.1e-24 S Protein of unknown function (DUF1056)
HPBIMMBF_00298 2.2e-210 S Phage portal protein
HPBIMMBF_00299 6.1e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HPBIMMBF_00300 1.4e-196 S Phage capsid family
HPBIMMBF_00301 2.4e-48 S Phage gp6-like head-tail connector protein
HPBIMMBF_00302 2.5e-56 S Phage head-tail joining protein
HPBIMMBF_00303 1.8e-66 S Bacteriophage HK97-gp10, putative tail-component
HPBIMMBF_00304 2.8e-45 S Protein of unknown function (DUF806)
HPBIMMBF_00305 2.3e-103 S Phage tail tube protein
HPBIMMBF_00306 1.3e-55 S Phage tail assembly chaperone proteins, TAC
HPBIMMBF_00307 1.5e-23
HPBIMMBF_00308 0.0 D NLP P60 protein
HPBIMMBF_00309 1e-214 S Phage tail protein
HPBIMMBF_00310 6.3e-292 S Phage minor structural protein
HPBIMMBF_00311 1.4e-134
HPBIMMBF_00314 3.2e-64
HPBIMMBF_00315 6e-19
HPBIMMBF_00316 1.3e-20
HPBIMMBF_00317 5.7e-198 lys M Glycosyl hydrolases family 25
HPBIMMBF_00318 2.4e-35 S Haemolysin XhlA
HPBIMMBF_00319 9.9e-14 hol S Bacteriophage holin
HPBIMMBF_00321 5.8e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HPBIMMBF_00322 3.7e-64
HPBIMMBF_00323 2.4e-76
HPBIMMBF_00324 7.4e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HPBIMMBF_00325 4.1e-86
HPBIMMBF_00326 3.2e-94 alkD L DNA alkylation repair enzyme
HPBIMMBF_00327 9.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPBIMMBF_00328 2.9e-36 ynzC S UPF0291 protein
HPBIMMBF_00329 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
HPBIMMBF_00330 1.2e-117 plsC 2.3.1.51 I Acyltransferase
HPBIMMBF_00331 1.9e-133 yabB 2.1.1.223 L Methyltransferase small domain
HPBIMMBF_00332 8.2e-48 yazA L GIY-YIG catalytic domain protein
HPBIMMBF_00333 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPBIMMBF_00334 2.6e-132 S Haloacid dehalogenase-like hydrolase
HPBIMMBF_00335 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HPBIMMBF_00336 5.7e-150 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPBIMMBF_00337 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HPBIMMBF_00338 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPBIMMBF_00339 4.4e-146 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPBIMMBF_00340 1.4e-136 cdsA 2.7.7.41 I Belongs to the CDS family
HPBIMMBF_00341 6.8e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HPBIMMBF_00342 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPBIMMBF_00343 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPBIMMBF_00344 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HPBIMMBF_00345 4.2e-212 nusA K Participates in both transcription termination and antitermination
HPBIMMBF_00346 1.6e-48 ylxR K Protein of unknown function (DUF448)
HPBIMMBF_00347 1.1e-47 ylxQ J ribosomal protein
HPBIMMBF_00348 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPBIMMBF_00349 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPBIMMBF_00350 2.3e-12 S Protein of unknown function (DUF3892)
HPBIMMBF_00351 2.5e-31 U Preprotein translocase subunit SecB
HPBIMMBF_00352 1.2e-44
HPBIMMBF_00355 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00356 5.7e-200 pre D Plasmid recombination enzyme
HPBIMMBF_00357 3.6e-23
HPBIMMBF_00359 4.6e-29 L RePlication protein
HPBIMMBF_00360 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPBIMMBF_00361 9.2e-86 L COG2801 Transposase and inactivated derivatives
HPBIMMBF_00362 1.4e-43 lacR K Transcriptional regulator
HPBIMMBF_00363 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPBIMMBF_00364 6e-143 mdtH P Sugar (and other) transporter
HPBIMMBF_00365 4.5e-171 S MobA/MobL family
HPBIMMBF_00368 1.4e-14
HPBIMMBF_00369 1.5e-42 S COG NOG38524 non supervised orthologous group
HPBIMMBF_00371 4.3e-148 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPBIMMBF_00372 5.3e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HPBIMMBF_00373 2.9e-269 yjcE P Sodium proton antiporter
HPBIMMBF_00374 2.4e-212 yttB EGP Major facilitator Superfamily
HPBIMMBF_00376 5.1e-47 V ATPases associated with a variety of cellular activities
HPBIMMBF_00378 1.1e-21 S CAAX protease self-immunity
HPBIMMBF_00381 4.4e-19 K Helix-turn-helix XRE-family like proteins
HPBIMMBF_00382 3.2e-225 sip L Belongs to the 'phage' integrase family
HPBIMMBF_00383 5.7e-14 K Cro/C1-type HTH DNA-binding domain
HPBIMMBF_00385 7e-10
HPBIMMBF_00386 4e-28
HPBIMMBF_00387 2.6e-149 L DNA replication protein
HPBIMMBF_00388 7.6e-266 S Virulence-associated protein E
HPBIMMBF_00389 1.1e-86
HPBIMMBF_00390 2.3e-24
HPBIMMBF_00391 2e-50 S head-tail joining protein
HPBIMMBF_00392 1.8e-81 terS L overlaps another CDS with the same product name
HPBIMMBF_00393 0.0 terL S overlaps another CDS with the same product name
HPBIMMBF_00395 5.2e-201 S Phage portal protein
HPBIMMBF_00396 2.1e-211 S Caudovirus prohead serine protease
HPBIMMBF_00397 8.6e-41 S Phage gp6-like head-tail connector protein
HPBIMMBF_00398 1.9e-57
HPBIMMBF_00401 8.9e-30
HPBIMMBF_00403 1.3e-193 int L Belongs to the 'phage' integrase family
HPBIMMBF_00405 3.3e-35 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HPBIMMBF_00406 2.7e-26
HPBIMMBF_00409 4.1e-13 S DNA/RNA non-specific endonuclease
HPBIMMBF_00410 2.7e-09 E peptidase
HPBIMMBF_00411 4.9e-21 K transcriptional
HPBIMMBF_00412 5.9e-07
HPBIMMBF_00414 7.7e-54
HPBIMMBF_00415 7.3e-81
HPBIMMBF_00416 4.3e-70
HPBIMMBF_00417 2.8e-157 recT L RecT family
HPBIMMBF_00418 1.2e-140 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HPBIMMBF_00419 2e-158 L DnaD domain protein
HPBIMMBF_00420 8.3e-50
HPBIMMBF_00421 3.1e-61 ps308 K AntA/AntB antirepressor
HPBIMMBF_00422 2.4e-87
HPBIMMBF_00423 2.6e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HPBIMMBF_00426 9.9e-39 S YopX protein
HPBIMMBF_00427 5.1e-42
HPBIMMBF_00430 1.5e-80 arpU S Transcriptional regulator, ArpU family
HPBIMMBF_00433 6.8e-10
HPBIMMBF_00434 3.7e-24 S Protein of unknown function (DUF2829)
HPBIMMBF_00435 6.5e-67 L Terminase small subunit
HPBIMMBF_00436 5.8e-252 S Phage terminase, large subunit
HPBIMMBF_00437 3.2e-303 S Phage portal protein, SPP1 Gp6-like
HPBIMMBF_00438 1.2e-169 S Phage Mu protein F like protein
HPBIMMBF_00439 3.2e-73 S Domain of unknown function (DUF4355)
HPBIMMBF_00440 8.2e-188 gpG
HPBIMMBF_00441 5e-60 S Phage gp6-like head-tail connector protein
HPBIMMBF_00442 4.8e-50
HPBIMMBF_00443 1.4e-93
HPBIMMBF_00444 4.9e-62
HPBIMMBF_00445 3.7e-94
HPBIMMBF_00446 2.5e-83 S Phage tail assembly chaperone protein, TAC
HPBIMMBF_00448 0.0 D NLP P60 protein
HPBIMMBF_00449 8.1e-134 S phage tail
HPBIMMBF_00450 3.1e-286 M Prophage endopeptidase tail
HPBIMMBF_00451 3.3e-170 E GDSL-like Lipase/Acylhydrolase family
HPBIMMBF_00452 3.5e-87 S Domain of unknown function (DUF2479)
HPBIMMBF_00457 5.5e-80
HPBIMMBF_00458 6.4e-23
HPBIMMBF_00459 4.1e-20
HPBIMMBF_00460 2.3e-199 lys M Glycosyl hydrolases family 25
HPBIMMBF_00461 1.8e-35 S Haemolysin XhlA
HPBIMMBF_00462 1.4e-30 hol S Bacteriophage holin
HPBIMMBF_00463 5.2e-117 Z012_01130 S Fic/DOC family
HPBIMMBF_00464 4.7e-133 yxkH G Polysaccharide deacetylase
HPBIMMBF_00465 1.2e-64 S Protein of unknown function (DUF1093)
HPBIMMBF_00466 7.2e-311 ycfI V ABC transporter, ATP-binding protein
HPBIMMBF_00467 0.0 yfiC V ABC transporter
HPBIMMBF_00468 5.7e-127
HPBIMMBF_00469 7.1e-43
HPBIMMBF_00470 3.7e-85 K Transcriptional regulator PadR-like family
HPBIMMBF_00471 3.5e-258 P Major Facilitator Superfamily
HPBIMMBF_00472 2.3e-56 T Belongs to the universal stress protein A family
HPBIMMBF_00473 7.4e-249 mntH P H( )-stimulated, divalent metal cation uptake system
HPBIMMBF_00474 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00475 1.2e-208 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HPBIMMBF_00476 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00477 5.1e-129 S WxL domain surface cell wall-binding
HPBIMMBF_00478 3.3e-92 S Bacterial protein of unknown function (DUF916)
HPBIMMBF_00480 6.3e-114 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPBIMMBF_00481 2.2e-76 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPBIMMBF_00482 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPBIMMBF_00483 8.9e-08 O AAA domain (Cdc48 subfamily)
HPBIMMBF_00485 1.6e-28
HPBIMMBF_00486 1.1e-53
HPBIMMBF_00487 4.9e-52 Q Methyltransferase
HPBIMMBF_00488 9.8e-40
HPBIMMBF_00489 3e-25
HPBIMMBF_00490 4.4e-41
HPBIMMBF_00492 6.2e-144 pstS P Phosphate
HPBIMMBF_00493 1.7e-180 tagO 2.7.8.33, 2.7.8.35 M transferase
HPBIMMBF_00494 0.0 ydaO E amino acid
HPBIMMBF_00495 5.1e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPBIMMBF_00496 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPBIMMBF_00497 6.1e-109 ydiL S CAAX protease self-immunity
HPBIMMBF_00498 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPBIMMBF_00499 1.9e-307 uup S ABC transporter, ATP-binding protein
HPBIMMBF_00500 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPBIMMBF_00501 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HPBIMMBF_00502 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HPBIMMBF_00503 6.6e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HPBIMMBF_00504 9.1e-187 phnD P Phosphonate ABC transporter
HPBIMMBF_00505 8.2e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPBIMMBF_00506 3.8e-137 phnE 3.6.1.63 U Phosphonate ABC transporter permease
HPBIMMBF_00507 5.9e-144 phnE1 3.6.1.63 U ABC transporter permease
HPBIMMBF_00508 1.9e-144 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
HPBIMMBF_00509 2.6e-208 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HPBIMMBF_00510 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPBIMMBF_00511 8.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
HPBIMMBF_00512 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPBIMMBF_00513 1e-57 yabA L Involved in initiation control of chromosome replication
HPBIMMBF_00514 3.3e-186 holB 2.7.7.7 L DNA polymerase III
HPBIMMBF_00515 2.4e-53 yaaQ S Cyclic-di-AMP receptor
HPBIMMBF_00516 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPBIMMBF_00517 2.2e-38 yaaL S Protein of unknown function (DUF2508)
HPBIMMBF_00518 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPBIMMBF_00519 1.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPBIMMBF_00520 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPBIMMBF_00521 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPBIMMBF_00522 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
HPBIMMBF_00523 6.5e-37 nrdH O Glutaredoxin
HPBIMMBF_00524 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPBIMMBF_00525 1.1e-197 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPBIMMBF_00526 2.1e-108 yvdD 3.2.2.10 S Belongs to the LOG family
HPBIMMBF_00527 2.5e-41 K Helix-turn-helix domain
HPBIMMBF_00528 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPBIMMBF_00529 1.5e-38 L nuclease
HPBIMMBF_00530 1.9e-178 F DNA/RNA non-specific endonuclease
HPBIMMBF_00531 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPBIMMBF_00532 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPBIMMBF_00533 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPBIMMBF_00534 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPBIMMBF_00535 2.4e-156 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_00536 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
HPBIMMBF_00537 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPBIMMBF_00538 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPBIMMBF_00539 9.1e-101 sigH K Sigma-70 region 2
HPBIMMBF_00540 5.4e-98 yacP S YacP-like NYN domain
HPBIMMBF_00541 1.6e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPBIMMBF_00542 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPBIMMBF_00543 6.7e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPBIMMBF_00544 7.5e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPBIMMBF_00545 2.4e-204 yacL S domain protein
HPBIMMBF_00546 4.9e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPBIMMBF_00547 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HPBIMMBF_00548 2.2e-50 HA62_12640 S GCN5-related N-acetyl-transferase
HPBIMMBF_00549 7.1e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPBIMMBF_00550 2.1e-257 pepC 3.4.22.40 E Peptidase C1-like family
HPBIMMBF_00551 1.1e-56 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPBIMMBF_00552 1.2e-39 K prlF antitoxin for toxin YhaV_toxin
HPBIMMBF_00553 9.4e-109 L Integrase
HPBIMMBF_00554 6.3e-70
HPBIMMBF_00555 1.2e-36 cps2I S Psort location CytoplasmicMembrane, score
HPBIMMBF_00557 5.2e-161 L hmm pf00665
HPBIMMBF_00558 3.1e-130 L Helix-turn-helix domain
HPBIMMBF_00559 1.5e-79 ydhK M Protein of unknown function (DUF1541)
HPBIMMBF_00560 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00561 1.7e-13 S Bacterial protein of unknown function (DUF916)
HPBIMMBF_00563 2e-56 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_00564 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HPBIMMBF_00567 2.5e-15 K Transcriptional regulator PadR-like family
HPBIMMBF_00569 3.7e-111 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPBIMMBF_00570 1.5e-115
HPBIMMBF_00571 1.2e-115
HPBIMMBF_00573 3e-158 S Bacterial protein of unknown function (DUF916)
HPBIMMBF_00574 5e-91 S Cell surface protein
HPBIMMBF_00575 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPBIMMBF_00576 3.9e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPBIMMBF_00577 2.4e-125 jag S R3H domain protein
HPBIMMBF_00578 6.9e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPBIMMBF_00579 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPBIMMBF_00580 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPBIMMBF_00581 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPBIMMBF_00582 1.9e-36 yaaA S S4 domain protein YaaA
HPBIMMBF_00583 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPBIMMBF_00584 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPBIMMBF_00585 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPBIMMBF_00586 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HPBIMMBF_00587 4.3e-64 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPBIMMBF_00588 3.1e-34 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPBIMMBF_00589 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HPBIMMBF_00590 1.4e-67 rplI J Binds to the 23S rRNA
HPBIMMBF_00591 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HPBIMMBF_00592 8.8e-226 yttB EGP Major facilitator Superfamily
HPBIMMBF_00593 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPBIMMBF_00594 7.3e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPBIMMBF_00596 1e-274 E ABC transporter, substratebinding protein
HPBIMMBF_00598 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPBIMMBF_00599 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPBIMMBF_00600 4.1e-196 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HPBIMMBF_00601 5.8e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HPBIMMBF_00602 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPBIMMBF_00603 5.8e-85 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPBIMMBF_00604 5.7e-302 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HPBIMMBF_00606 6.5e-142 S haloacid dehalogenase-like hydrolase
HPBIMMBF_00607 3.9e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HPBIMMBF_00608 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HPBIMMBF_00609 2e-32 S Pyridoxamine 5'-phosphate oxidase
HPBIMMBF_00610 7.9e-35 S Pyridoxamine 5'-phosphate oxidase
HPBIMMBF_00611 1.6e-31 cspA K Cold shock protein domain
HPBIMMBF_00612 1.7e-37
HPBIMMBF_00614 6.2e-131 K response regulator
HPBIMMBF_00615 0.0 vicK 2.7.13.3 T Histidine kinase
HPBIMMBF_00616 2e-244 yycH S YycH protein
HPBIMMBF_00617 1.9e-150 yycI S YycH protein
HPBIMMBF_00618 8.9e-158 vicX 3.1.26.11 S domain protein
HPBIMMBF_00619 3e-168 htrA 3.4.21.107 O serine protease
HPBIMMBF_00620 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPBIMMBF_00621 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00622 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00624 9.7e-222 L Transposase
HPBIMMBF_00630 5.1e-08
HPBIMMBF_00637 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00638 4.9e-87 nrdI F Belongs to the NrdI family
HPBIMMBF_00639 9.8e-39 L Transposase and inactivated derivatives
HPBIMMBF_00640 4.4e-18
HPBIMMBF_00641 2.3e-08 S Transglycosylase associated protein
HPBIMMBF_00643 5.7e-191 L PFAM Integrase, catalytic core
HPBIMMBF_00644 1.4e-175 L Integrase core domain
HPBIMMBF_00645 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPBIMMBF_00646 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPBIMMBF_00647 6.5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
HPBIMMBF_00648 1.2e-30 secG U Preprotein translocase
HPBIMMBF_00649 8.1e-293 clcA P chloride
HPBIMMBF_00650 1.3e-130
HPBIMMBF_00651 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPBIMMBF_00652 1.6e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPBIMMBF_00653 3.1e-223 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HPBIMMBF_00654 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPBIMMBF_00655 1e-187 cggR K Putative sugar-binding domain
HPBIMMBF_00656 9.3e-245 rpoN K Sigma-54 factor, core binding domain
HPBIMMBF_00658 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPBIMMBF_00659 1e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPBIMMBF_00660 2.6e-305 oppA E ABC transporter, substratebinding protein
HPBIMMBF_00661 3.7e-168 whiA K May be required for sporulation
HPBIMMBF_00662 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HPBIMMBF_00663 1.1e-161 rapZ S Displays ATPase and GTPase activities
HPBIMMBF_00664 9.3e-87 S Short repeat of unknown function (DUF308)
HPBIMMBF_00665 2.7e-263 argH 4.3.2.1 E argininosuccinate lyase
HPBIMMBF_00666 5.4e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPBIMMBF_00667 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPBIMMBF_00668 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPBIMMBF_00669 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPBIMMBF_00670 1.4e-116 yfbR S HD containing hydrolase-like enzyme
HPBIMMBF_00671 2.7e-211 norA EGP Major facilitator Superfamily
HPBIMMBF_00672 6.2e-102 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HPBIMMBF_00673 1.5e-258 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPBIMMBF_00674 2.8e-131 yliE T Putative diguanylate phosphodiesterase
HPBIMMBF_00675 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HPBIMMBF_00676 3.3e-61 S Protein of unknown function (DUF3290)
HPBIMMBF_00677 1.2e-18 yviA S Protein of unknown function (DUF421)
HPBIMMBF_00678 1.8e-81 yviA S Protein of unknown function (DUF421)
HPBIMMBF_00679 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPBIMMBF_00680 2e-131 2.7.7.65 T diguanylate cyclase activity
HPBIMMBF_00681 1e-98 ydaN S Bacterial cellulose synthase subunit
HPBIMMBF_00682 4.5e-126 ydaN S Bacterial cellulose synthase subunit
HPBIMMBF_00683 7.5e-58 ydaN S Bacterial cellulose synthase subunit
HPBIMMBF_00684 1.2e-43 ydaM M Glycosyl transferase family group 2
HPBIMMBF_00685 5e-151 ydaM M Glycosyl transferase family group 2
HPBIMMBF_00686 3.8e-205 S Protein conserved in bacteria
HPBIMMBF_00687 3.8e-155
HPBIMMBF_00688 6.9e-64
HPBIMMBF_00689 3.1e-161 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HPBIMMBF_00690 3e-159 nox C NADH oxidase
HPBIMMBF_00691 1.8e-11 tnpR L Resolvase, N terminal domain
HPBIMMBF_00692 8.3e-87 L COG2801 Transposase and inactivated derivatives
HPBIMMBF_00693 1.1e-161 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00694 9.8e-34 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HPBIMMBF_00695 1.5e-67 tnp2PF3 L Transposase
HPBIMMBF_00696 5.1e-68 L Putative transposase of IS4/5 family (DUF4096)
HPBIMMBF_00697 5.4e-77 L Transposase DDE domain
HPBIMMBF_00698 2.4e-86 L COG2801 Transposase and inactivated derivatives
HPBIMMBF_00699 7.1e-58 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HPBIMMBF_00700 1e-81 tnp2PF3 L Transposase DDE domain
HPBIMMBF_00701 1.5e-117 L PFAM Integrase catalytic region
HPBIMMBF_00702 8.3e-72 L PFAM Integrase catalytic region
HPBIMMBF_00703 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPBIMMBF_00704 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HPBIMMBF_00705 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HPBIMMBF_00706 1.5e-264 lysP E amino acid
HPBIMMBF_00707 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HPBIMMBF_00708 2.1e-91 K Transcriptional regulator
HPBIMMBF_00709 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
HPBIMMBF_00710 2e-154 I alpha/beta hydrolase fold
HPBIMMBF_00711 2.3e-119 lssY 3.6.1.27 I phosphatase
HPBIMMBF_00712 2.1e-188 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPBIMMBF_00713 2.2e-76 S Threonine/Serine exporter, ThrE
HPBIMMBF_00714 1.5e-130 thrE S Putative threonine/serine exporter
HPBIMMBF_00715 6e-31 cspC K Cold shock protein
HPBIMMBF_00716 2e-120 sirR K iron dependent repressor
HPBIMMBF_00717 2.6e-58
HPBIMMBF_00718 1.7e-84 merR K MerR HTH family regulatory protein
HPBIMMBF_00719 2e-269 lmrB EGP Major facilitator Superfamily
HPBIMMBF_00720 5.5e-111 S Domain of unknown function (DUF4811)
HPBIMMBF_00721 2.9e-106
HPBIMMBF_00722 4.4e-35 yyaN K MerR HTH family regulatory protein
HPBIMMBF_00723 1.4e-119 azlC E branched-chain amino acid
HPBIMMBF_00724 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HPBIMMBF_00725 0.0 asnB 6.3.5.4 E Asparagine synthase
HPBIMMBF_00726 7.8e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HPBIMMBF_00727 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPBIMMBF_00728 5.7e-253 xylP2 G symporter
HPBIMMBF_00729 4.2e-189 nlhH_1 I alpha/beta hydrolase fold
HPBIMMBF_00730 5.6e-49
HPBIMMBF_00731 1.4e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPBIMMBF_00732 3.1e-101 3.2.2.20 K FR47-like protein
HPBIMMBF_00733 1.3e-126 yibF S overlaps another CDS with the same product name
HPBIMMBF_00734 1.9e-220 yibE S overlaps another CDS with the same product name
HPBIMMBF_00735 1.1e-178
HPBIMMBF_00736 4.8e-137 S NADPH-dependent FMN reductase
HPBIMMBF_00737 1.6e-49 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPBIMMBF_00738 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HPBIMMBF_00739 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HPBIMMBF_00740 4.1e-32 L leucine-zipper of insertion element IS481
HPBIMMBF_00741 8.5e-41
HPBIMMBF_00742 2.3e-218 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HPBIMMBF_00743 4.8e-276 pipD E Dipeptidase
HPBIMMBF_00744 3.8e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
HPBIMMBF_00745 6.2e-254 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HPBIMMBF_00746 3.7e-38 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPBIMMBF_00747 7.4e-58 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPBIMMBF_00748 9.7e-80 rmaD K Transcriptional regulator
HPBIMMBF_00749 2.1e-105 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPBIMMBF_00750 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00751 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_00752 3.5e-16 M domain protein
HPBIMMBF_00753 9.7e-240 M domain protein
HPBIMMBF_00754 1.1e-72 yjcF S Acetyltransferase (GNAT) domain
HPBIMMBF_00755 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPBIMMBF_00756 0.0 glpQ 3.1.4.46 C phosphodiesterase
HPBIMMBF_00758 8.9e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HPBIMMBF_00759 8.3e-76 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_00760 5e-181 3.6.4.13 S domain, Protein
HPBIMMBF_00761 3.6e-168 S Polyphosphate kinase 2 (PPK2)
HPBIMMBF_00762 1.2e-97 drgA C Nitroreductase family
HPBIMMBF_00763 1.2e-177 iunH2 3.2.2.1 F nucleoside hydrolase
HPBIMMBF_00764 3.7e-149 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPBIMMBF_00765 2e-122 S Sucrose-6F-phosphate phosphohydrolase
HPBIMMBF_00766 2.3e-157 ccpB 5.1.1.1 K lacI family
HPBIMMBF_00767 1.8e-116 K Helix-turn-helix domain, rpiR family
HPBIMMBF_00768 6e-177 S Oxidoreductase family, NAD-binding Rossmann fold
HPBIMMBF_00769 6.5e-198 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
HPBIMMBF_00770 0.0 yjcE P Sodium proton antiporter
HPBIMMBF_00771 1.5e-241 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPBIMMBF_00772 4.7e-85 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPBIMMBF_00773 4.1e-106 pncA Q Isochorismatase family
HPBIMMBF_00774 1.4e-131
HPBIMMBF_00775 5.1e-125 skfE V ABC transporter
HPBIMMBF_00776 2.8e-64 yvoA_1 K Transcriptional regulator, GntR family
HPBIMMBF_00777 6e-45 S Enterocin A Immunity
HPBIMMBF_00778 7.7e-174 D Alpha beta
HPBIMMBF_00779 0.0 pepF2 E Oligopeptidase F
HPBIMMBF_00780 1.3e-72 K Transcriptional regulator
HPBIMMBF_00781 8.7e-164
HPBIMMBF_00782 6e-58
HPBIMMBF_00783 4.2e-46
HPBIMMBF_00784 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPBIMMBF_00785 1.9e-68
HPBIMMBF_00786 8.4e-145 yjfP S Dienelactone hydrolase family
HPBIMMBF_00787 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
HPBIMMBF_00788 1.3e-204 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HPBIMMBF_00789 2e-46
HPBIMMBF_00790 4.1e-44
HPBIMMBF_00791 2.5e-81 yybC S Protein of unknown function (DUF2798)
HPBIMMBF_00792 4.1e-72
HPBIMMBF_00793 2.7e-59
HPBIMMBF_00794 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HPBIMMBF_00795 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
HPBIMMBF_00796 2.6e-14 L Transposase
HPBIMMBF_00797 3.3e-70 K LysR substrate binding domain
HPBIMMBF_00798 4.9e-63 S Domain of unknown function (DUF4440)
HPBIMMBF_00799 1.2e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
HPBIMMBF_00800 8.2e-48
HPBIMMBF_00801 3.2e-37
HPBIMMBF_00802 2.8e-85 yvbK 3.1.3.25 K GNAT family
HPBIMMBF_00803 1.4e-83
HPBIMMBF_00804 1.3e-111 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPBIMMBF_00805 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPBIMMBF_00806 4.2e-99 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPBIMMBF_00807 4e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPBIMMBF_00809 7.5e-121 macB V ABC transporter, ATP-binding protein
HPBIMMBF_00810 0.0 ylbB V ABC transporter permease
HPBIMMBF_00811 1.1e-234 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HPBIMMBF_00813 1.4e-47 XK27_04080 H RibD C-terminal domain
HPBIMMBF_00814 4.9e-78 K transcriptional regulator, MerR family
HPBIMMBF_00815 3.2e-76 yphH S Cupin domain
HPBIMMBF_00816 8.7e-51 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HPBIMMBF_00817 3e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPBIMMBF_00818 4.7e-211 natB CP ABC-2 family transporter protein
HPBIMMBF_00819 3.1e-167 natA S ABC transporter, ATP-binding protein
HPBIMMBF_00820 5.2e-92 ogt 2.1.1.63 L Methyltransferase
HPBIMMBF_00821 2.3e-52 lytE M LysM domain
HPBIMMBF_00823 2.6e-267 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
HPBIMMBF_00824 3.2e-294 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HPBIMMBF_00825 3.7e-151 rlrG K Transcriptional regulator
HPBIMMBF_00826 3.5e-172 S Conserved hypothetical protein 698
HPBIMMBF_00827 8.1e-102 rimL J Acetyltransferase (GNAT) domain
HPBIMMBF_00828 4.5e-34 S Domain of unknown function (DUF4811)
HPBIMMBF_00829 1.2e-269 lmrB EGP Major facilitator Superfamily
HPBIMMBF_00830 1.8e-124 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPBIMMBF_00831 7.6e-190 ynfM EGP Major facilitator Superfamily
HPBIMMBF_00832 6e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HPBIMMBF_00833 1.4e-154 mleP3 S Membrane transport protein
HPBIMMBF_00834 9.2e-108 S Membrane
HPBIMMBF_00835 1.8e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPBIMMBF_00836 8.1e-99 1.5.1.3 H RibD C-terminal domain
HPBIMMBF_00837 2.5e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HPBIMMBF_00838 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
HPBIMMBF_00839 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HPBIMMBF_00840 1.5e-173 hrtB V ABC transporter permease
HPBIMMBF_00841 6.6e-95 S Protein of unknown function (DUF1440)
HPBIMMBF_00842 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPBIMMBF_00843 8.4e-148 KT helix_turn_helix, mercury resistance
HPBIMMBF_00846 2e-32 zmp2 O Zinc-dependent metalloprotease
HPBIMMBF_00847 1.1e-65 zmp2 O Zinc-dependent metalloprotease
HPBIMMBF_00848 6.1e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPBIMMBF_00849 3.1e-176 EG EamA-like transporter family
HPBIMMBF_00850 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HPBIMMBF_00851 1.2e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPBIMMBF_00852 1.8e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HPBIMMBF_00853 2e-138 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPBIMMBF_00854 9.8e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
HPBIMMBF_00855 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
HPBIMMBF_00856 1.6e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPBIMMBF_00857 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HPBIMMBF_00858 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
HPBIMMBF_00859 0.0 levR K Sigma-54 interaction domain
HPBIMMBF_00860 4.7e-64 S Domain of unknown function (DUF956)
HPBIMMBF_00861 4e-170 manN G system, mannose fructose sorbose family IID component
HPBIMMBF_00862 8.1e-135 manY G PTS system
HPBIMMBF_00863 1.5e-167 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HPBIMMBF_00864 1e-153 G Peptidase_C39 like family
HPBIMMBF_00866 2.6e-155 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPBIMMBF_00867 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HPBIMMBF_00868 2e-82 ydcK S Belongs to the SprT family
HPBIMMBF_00869 0.0 yhgF K Tex-like protein N-terminal domain protein
HPBIMMBF_00870 8.9e-72
HPBIMMBF_00871 0.0 pacL 3.6.3.8 P P-type ATPase
HPBIMMBF_00872 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPBIMMBF_00873 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPBIMMBF_00874 1.2e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HPBIMMBF_00875 1.8e-122 gntR1 K UbiC transcription regulator-associated domain protein
HPBIMMBF_00876 5.1e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPBIMMBF_00877 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPBIMMBF_00878 3.5e-120 pnuC H nicotinamide mononucleotide transporter
HPBIMMBF_00879 5.6e-84 ybiR P Citrate transporter
HPBIMMBF_00880 1.3e-70 ybiR P Citrate transporter
HPBIMMBF_00881 1.1e-166 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HPBIMMBF_00882 2.5e-53 S Cupin domain
HPBIMMBF_00883 6.5e-48 5.3.3.19 S Cupin 2, conserved barrel domain protein
HPBIMMBF_00887 2e-151 yjjH S Calcineurin-like phosphoesterase
HPBIMMBF_00888 3.9e-252 dtpT U amino acid peptide transporter
HPBIMMBF_00892 7e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HPBIMMBF_00893 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HPBIMMBF_00894 3.2e-86 ykuL S (CBS) domain
HPBIMMBF_00895 4.7e-96 S Phosphoesterase
HPBIMMBF_00896 3e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPBIMMBF_00897 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HPBIMMBF_00898 1.9e-92 yslB S Protein of unknown function (DUF2507)
HPBIMMBF_00899 3.3e-52 trxA O Belongs to the thioredoxin family
HPBIMMBF_00900 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPBIMMBF_00901 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HPBIMMBF_00902 1.6e-48 yrzB S Belongs to the UPF0473 family
HPBIMMBF_00903 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPBIMMBF_00904 2.4e-43 yrzL S Belongs to the UPF0297 family
HPBIMMBF_00905 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPBIMMBF_00906 4.6e-244 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPBIMMBF_00907 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HPBIMMBF_00908 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPBIMMBF_00909 2.8e-29 yajC U Preprotein translocase
HPBIMMBF_00910 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPBIMMBF_00911 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPBIMMBF_00912 6e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPBIMMBF_00913 7.8e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPBIMMBF_00914 9.6e-89
HPBIMMBF_00915 0.0 S Bacterial membrane protein YfhO
HPBIMMBF_00916 8.2e-72
HPBIMMBF_00917 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPBIMMBF_00918 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPBIMMBF_00919 2.7e-154 ymdB S YmdB-like protein
HPBIMMBF_00920 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
HPBIMMBF_00921 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPBIMMBF_00922 1.4e-229 cinA 3.5.1.42 S Belongs to the CinA family
HPBIMMBF_00923 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPBIMMBF_00924 5.7e-110 ymfM S Helix-turn-helix domain
HPBIMMBF_00925 3.2e-250 ymfH S Peptidase M16
HPBIMMBF_00926 1.6e-230 ymfF S Peptidase M16 inactive domain protein
HPBIMMBF_00927 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HPBIMMBF_00928 1.5e-155 aatB ET ABC transporter substrate-binding protein
HPBIMMBF_00929 1.6e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPBIMMBF_00930 4.6e-109 glnP P ABC transporter permease
HPBIMMBF_00931 1.2e-146 minD D Belongs to the ParA family
HPBIMMBF_00932 3.4e-115 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HPBIMMBF_00933 1.2e-88 mreD M rod shape-determining protein MreD
HPBIMMBF_00934 2.6e-144 mreC M Involved in formation and maintenance of cell shape
HPBIMMBF_00935 2.8e-161 mreB D cell shape determining protein MreB
HPBIMMBF_00936 4.7e-54 radC L DNA repair protein
HPBIMMBF_00937 6.3e-44 radC L DNA repair protein
HPBIMMBF_00938 1.9e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPBIMMBF_00939 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPBIMMBF_00940 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPBIMMBF_00941 2.6e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HPBIMMBF_00942 2.3e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPBIMMBF_00943 2.7e-216 iscS2 2.8.1.7 E Aminotransferase class V
HPBIMMBF_00945 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPBIMMBF_00946 1.9e-80 ytsP 1.8.4.14 T GAF domain-containing protein
HPBIMMBF_00947 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPBIMMBF_00948 5.2e-113 yktB S Belongs to the UPF0637 family
HPBIMMBF_00949 9.5e-80 yueI S Protein of unknown function (DUF1694)
HPBIMMBF_00950 3.1e-110 S Protein of unknown function (DUF1648)
HPBIMMBF_00951 8.6e-44 czrA K Helix-turn-helix domain
HPBIMMBF_00952 6.7e-232 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HPBIMMBF_00953 2.9e-40 2.7.1.191 G PTS system fructose IIA component
HPBIMMBF_00954 3.5e-104 G PTS system mannose fructose sorbose family IID component
HPBIMMBF_00955 3.6e-103 G PTS system sorbose-specific iic component
HPBIMMBF_00956 1.3e-63 2.7.1.191 G PTS system sorbose subfamily IIB component
HPBIMMBF_00957 7.8e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HPBIMMBF_00958 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HPBIMMBF_00959 1e-237 rarA L recombination factor protein RarA
HPBIMMBF_00960 1.5e-38
HPBIMMBF_00961 6.2e-82 usp6 T universal stress protein
HPBIMMBF_00962 1.2e-171 bla2 3.5.2.6 V Beta-lactamase enzyme family
HPBIMMBF_00963 4.7e-160 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HPBIMMBF_00964 2.6e-291 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HPBIMMBF_00965 2.3e-212 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HPBIMMBF_00966 2.3e-187 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPBIMMBF_00967 3.5e-177 S Protein of unknown function (DUF2785)
HPBIMMBF_00968 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
HPBIMMBF_00969 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
HPBIMMBF_00970 1.4e-111 metI U ABC transporter permease
HPBIMMBF_00971 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPBIMMBF_00972 3.6e-48 gcsH2 E glycine cleavage
HPBIMMBF_00973 9.3e-220 rodA D Belongs to the SEDS family
HPBIMMBF_00974 3.3e-33 S Protein of unknown function (DUF2969)
HPBIMMBF_00975 7.9e-44 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HPBIMMBF_00976 2.7e-180 mbl D Cell shape determining protein MreB Mrl
HPBIMMBF_00977 1.1e-101 J Acetyltransferase (GNAT) domain
HPBIMMBF_00978 7.5e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPBIMMBF_00979 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HPBIMMBF_00980 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPBIMMBF_00981 6.7e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPBIMMBF_00982 7.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPBIMMBF_00983 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPBIMMBF_00984 2.3e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPBIMMBF_00985 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPBIMMBF_00986 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HPBIMMBF_00987 1e-232 pyrP F Permease
HPBIMMBF_00988 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPBIMMBF_00989 2.1e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPBIMMBF_00990 3.2e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPBIMMBF_00991 9.5e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPBIMMBF_00992 1.5e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPBIMMBF_00993 9.3e-109 tdk 2.7.1.21 F thymidine kinase
HPBIMMBF_00994 7.6e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HPBIMMBF_00995 1.9e-135 cobQ S glutamine amidotransferase
HPBIMMBF_00996 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPBIMMBF_00997 1.4e-192 ampC V Beta-lactamase
HPBIMMBF_00998 1.4e-29
HPBIMMBF_00999 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HPBIMMBF_01000 1.9e-58
HPBIMMBF_01001 7.4e-63 L Integrase core domain
HPBIMMBF_01002 1.2e-261 ydiN 5.4.99.5 G Major Facilitator
HPBIMMBF_01003 5.1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPBIMMBF_01004 4.2e-92
HPBIMMBF_01005 6.5e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPBIMMBF_01006 4e-193 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HPBIMMBF_01007 6.9e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPBIMMBF_01008 3.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPBIMMBF_01009 1.9e-186 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HPBIMMBF_01010 2.5e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HPBIMMBF_01011 2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPBIMMBF_01012 3e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPBIMMBF_01013 0.0 dnaK O Heat shock 70 kDa protein
HPBIMMBF_01014 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPBIMMBF_01015 5.7e-198 pbpX2 V Beta-lactamase
HPBIMMBF_01016 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
HPBIMMBF_01017 7.9e-111 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPBIMMBF_01018 7e-175 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPBIMMBF_01019 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HPBIMMBF_01020 1.2e-33 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPBIMMBF_01021 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPBIMMBF_01022 8.9e-26
HPBIMMBF_01023 7.4e-64 XK27_01125 L IS66 Orf2 like protein
HPBIMMBF_01024 4e-223 L Transposase IS66 family
HPBIMMBF_01025 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPBIMMBF_01026 2.3e-47
HPBIMMBF_01027 1.4e-49
HPBIMMBF_01028 2e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HPBIMMBF_01029 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
HPBIMMBF_01030 1.8e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPBIMMBF_01031 3.7e-57
HPBIMMBF_01032 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPBIMMBF_01033 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPBIMMBF_01034 3.3e-112 3.1.3.18 J HAD-hyrolase-like
HPBIMMBF_01035 1.2e-162 yniA G Fructosamine kinase
HPBIMMBF_01036 2.1e-154 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HPBIMMBF_01037 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HPBIMMBF_01038 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPBIMMBF_01039 5.2e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPBIMMBF_01040 3.9e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPBIMMBF_01041 1.2e-221 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPBIMMBF_01042 3.6e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPBIMMBF_01043 1.3e-202 yfbS P Sodium:sulfate symporter transmembrane region
HPBIMMBF_01044 3.8e-251 L Transposase DDE domain group 1
HPBIMMBF_01045 8.8e-94 yfbS P Sodium:sulfate symporter transmembrane region
HPBIMMBF_01046 6.2e-244 dinF V MatE
HPBIMMBF_01047 1.9e-31
HPBIMMBF_01050 2.9e-78 elaA S Acetyltransferase (GNAT) domain
HPBIMMBF_01051 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HPBIMMBF_01052 1.7e-79
HPBIMMBF_01053 1.1e-78 yhcA V MacB-like periplasmic core domain
HPBIMMBF_01054 2.1e-269 yhcA V MacB-like periplasmic core domain
HPBIMMBF_01055 2.9e-106
HPBIMMBF_01056 0.0 K PRD domain
HPBIMMBF_01057 2.4e-62 S Domain of unknown function (DUF3284)
HPBIMMBF_01058 3e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HPBIMMBF_01059 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPBIMMBF_01060 6.1e-220 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_01061 2.5e-155 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPBIMMBF_01062 4.7e-84 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPBIMMBF_01063 7.7e-211 EGP Major facilitator Superfamily
HPBIMMBF_01064 1.7e-113 M ErfK YbiS YcfS YnhG
HPBIMMBF_01065 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPBIMMBF_01066 7.1e-283 ydfD K Alanine-glyoxylate amino-transferase
HPBIMMBF_01067 6.9e-100 argO S LysE type translocator
HPBIMMBF_01068 1.7e-212 arcT 2.6.1.1 E Aminotransferase
HPBIMMBF_01069 4.4e-77 argR K Regulates arginine biosynthesis genes
HPBIMMBF_01070 8.5e-12
HPBIMMBF_01071 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HPBIMMBF_01072 3e-54 yheA S Belongs to the UPF0342 family
HPBIMMBF_01073 2.4e-231 yhaO L Ser Thr phosphatase family protein
HPBIMMBF_01074 0.0 L AAA domain
HPBIMMBF_01075 8.4e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPBIMMBF_01076 4e-212
HPBIMMBF_01077 7.8e-177 3.4.21.102 M Peptidase family S41
HPBIMMBF_01078 7.6e-177 K LysR substrate binding domain
HPBIMMBF_01079 1.4e-110 1.3.5.4 S NADPH-dependent FMN reductase
HPBIMMBF_01080 0.0 1.3.5.4 C FAD binding domain
HPBIMMBF_01081 3.9e-96
HPBIMMBF_01082 7.4e-74 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HPBIMMBF_01083 9.8e-39 L Transposase and inactivated derivatives
HPBIMMBF_01084 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
HPBIMMBF_01085 3.8e-226 patA 2.6.1.1 E Aminotransferase
HPBIMMBF_01086 1.9e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPBIMMBF_01087 2.4e-187 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPBIMMBF_01088 7.7e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
HPBIMMBF_01089 3.3e-222 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HPBIMMBF_01090 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPBIMMBF_01091 2.7e-39 ptsH G phosphocarrier protein HPR
HPBIMMBF_01092 2.5e-29
HPBIMMBF_01093 0.0 clpE O Belongs to the ClpA ClpB family
HPBIMMBF_01094 5.6e-12 L Integrase
HPBIMMBF_01095 1.3e-76 L Integrase
HPBIMMBF_01096 1e-63 K Winged helix DNA-binding domain
HPBIMMBF_01097 5.8e-180 oppF P Belongs to the ABC transporter superfamily
HPBIMMBF_01098 9.2e-203 oppD P Belongs to the ABC transporter superfamily
HPBIMMBF_01099 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPBIMMBF_01100 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPBIMMBF_01101 1.3e-309 oppA E ABC transporter, substratebinding protein
HPBIMMBF_01102 3.2e-57 ywjH S Protein of unknown function (DUF1634)
HPBIMMBF_01103 3.6e-125 yxaA S membrane transporter protein
HPBIMMBF_01104 5.7e-158 lysR5 K LysR substrate binding domain
HPBIMMBF_01105 9.4e-197 M MucBP domain
HPBIMMBF_01106 9.6e-152
HPBIMMBF_01107 1.4e-69
HPBIMMBF_01108 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPBIMMBF_01109 7.7e-252 gor 1.8.1.7 C Glutathione reductase
HPBIMMBF_01110 1.1e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HPBIMMBF_01111 5.1e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HPBIMMBF_01112 6.1e-212 gntP EG Gluconate
HPBIMMBF_01113 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HPBIMMBF_01114 1.3e-186 yueF S AI-2E family transporter
HPBIMMBF_01115 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HPBIMMBF_01116 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
HPBIMMBF_01117 7.8e-48 K sequence-specific DNA binding
HPBIMMBF_01118 1.5e-133 cwlO M NlpC/P60 family
HPBIMMBF_01119 4.1e-106 ygaC J Belongs to the UPF0374 family
HPBIMMBF_01120 2.4e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
HPBIMMBF_01121 3.9e-125
HPBIMMBF_01122 6.8e-101 K DNA-templated transcription, initiation
HPBIMMBF_01123 1.9e-26
HPBIMMBF_01124 1.4e-17
HPBIMMBF_01125 7.3e-33 S Protein of unknown function (DUF2922)
HPBIMMBF_01126 1.1e-52
HPBIMMBF_01127 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_01128 2.4e-94 M Glycosyltransferase, group 2 family protein
HPBIMMBF_01129 2.2e-72 S SnoaL-like domain
HPBIMMBF_01130 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HPBIMMBF_01131 4e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HPBIMMBF_01133 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPBIMMBF_01134 8.3e-110 ypsA S Belongs to the UPF0398 family
HPBIMMBF_01135 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPBIMMBF_01136 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HPBIMMBF_01137 2.8e-179 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
HPBIMMBF_01138 1.5e-169 ftpB P Bacterial extracellular solute-binding protein
HPBIMMBF_01139 3.3e-300 ftpA P Binding-protein-dependent transport system inner membrane component
HPBIMMBF_01140 7.6e-83 uspA T Universal stress protein family
HPBIMMBF_01141 3.6e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HPBIMMBF_01142 7.7e-99 metI P ABC transporter permease
HPBIMMBF_01143 2e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPBIMMBF_01145 6.6e-128 dnaD L Replication initiation and membrane attachment
HPBIMMBF_01146 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HPBIMMBF_01147 3.6e-224 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HPBIMMBF_01148 1e-71 ypmB S protein conserved in bacteria
HPBIMMBF_01149 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HPBIMMBF_01150 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HPBIMMBF_01151 4.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HPBIMMBF_01152 3.6e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HPBIMMBF_01153 1.8e-195 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPBIMMBF_01154 1.3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPBIMMBF_01155 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HPBIMMBF_01156 1.1e-248 malT G Major Facilitator
HPBIMMBF_01157 3.8e-90 S Domain of unknown function (DUF4767)
HPBIMMBF_01158 6.1e-268 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HPBIMMBF_01159 3e-84 yitU 3.1.3.104 S hydrolase
HPBIMMBF_01160 1.8e-265 yfnA E Amino Acid
HPBIMMBF_01161 5.3e-256 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HPBIMMBF_01162 1.8e-41
HPBIMMBF_01163 1.9e-49
HPBIMMBF_01164 1.6e-135 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
HPBIMMBF_01165 6.5e-38
HPBIMMBF_01166 5.9e-150
HPBIMMBF_01167 2.4e-14 lldP C L-lactate permease
HPBIMMBF_01168 1.3e-188 lldP C L-lactate permease
HPBIMMBF_01169 3.4e-44 lldP C L-lactate permease
HPBIMMBF_01170 5.9e-58
HPBIMMBF_01171 3.5e-115
HPBIMMBF_01172 6e-244 cycA E Amino acid permease
HPBIMMBF_01173 4.7e-133 XK27_00890 S Domain of unknown function (DUF368)
HPBIMMBF_01174 1.5e-128 yejC S Protein of unknown function (DUF1003)
HPBIMMBF_01175 2.3e-50 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HPBIMMBF_01176 2.3e-11
HPBIMMBF_01177 1.9e-209 pmrB EGP Major facilitator Superfamily
HPBIMMBF_01178 1.3e-148 2.7.7.12 C Domain of unknown function (DUF4931)
HPBIMMBF_01179 1.4e-49
HPBIMMBF_01180 3.6e-09
HPBIMMBF_01181 2.9e-131 S Protein of unknown function (DUF975)
HPBIMMBF_01182 5.4e-77 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HPBIMMBF_01183 7e-161 degV S EDD domain protein, DegV family
HPBIMMBF_01184 3.5e-65 K Transcriptional regulator
HPBIMMBF_01185 0.0 FbpA K Fibronectin-binding protein
HPBIMMBF_01186 3.7e-129 S ABC-2 family transporter protein
HPBIMMBF_01187 2.3e-162 V ABC transporter, ATP-binding protein
HPBIMMBF_01188 9.7e-91 3.6.1.55 F NUDIX domain
HPBIMMBF_01189 3e-133 S Uncharacterized protein conserved in bacteria (DUF2087)
HPBIMMBF_01190 1.2e-69 S LuxR family transcriptional regulator
HPBIMMBF_01191 6e-128 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HPBIMMBF_01193 9e-71 frataxin S Domain of unknown function (DU1801)
HPBIMMBF_01194 6.4e-113 pgm5 G Phosphoglycerate mutase family
HPBIMMBF_01195 5.7e-287 S Bacterial membrane protein, YfhO
HPBIMMBF_01196 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPBIMMBF_01197 3.1e-206 carA 6.3.5.5 F Belongs to the CarA family
HPBIMMBF_01198 9.7e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPBIMMBF_01199 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPBIMMBF_01200 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPBIMMBF_01201 1.7e-293 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HPBIMMBF_01202 3.3e-62 esbA S Family of unknown function (DUF5322)
HPBIMMBF_01203 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
HPBIMMBF_01204 1.1e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
HPBIMMBF_01205 1.5e-146 S hydrolase activity, acting on ester bonds
HPBIMMBF_01206 2e-189
HPBIMMBF_01207 8e-120 3.6.3.35 P ATPases associated with a variety of cellular activities
HPBIMMBF_01208 1.2e-124
HPBIMMBF_01209 4.5e-60 XK27_09885 V VanZ like family
HPBIMMBF_01211 9.2e-10 K Helix-turn-helix XRE-family like proteins
HPBIMMBF_01212 2.6e-106
HPBIMMBF_01213 3e-53 S Uncharacterized protein conserved in bacteria (DUF2316)
HPBIMMBF_01214 1.3e-158 4.1.1.46 S Amidohydrolase
HPBIMMBF_01215 1.6e-100 K transcriptional regulator
HPBIMMBF_01216 2.5e-183 yfeX P Peroxidase
HPBIMMBF_01217 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPBIMMBF_01218 1e-125 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HPBIMMBF_01219 1.5e-150 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HPBIMMBF_01220 3.2e-17 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HPBIMMBF_01221 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HPBIMMBF_01222 2.3e-139 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPBIMMBF_01223 3.3e-55 txlA O Thioredoxin-like domain
HPBIMMBF_01224 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
HPBIMMBF_01225 1.6e-18
HPBIMMBF_01226 4.7e-94 dps P Belongs to the Dps family
HPBIMMBF_01227 1.2e-32 copZ P Heavy-metal-associated domain
HPBIMMBF_01228 4.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HPBIMMBF_01229 0.0 pepO 3.4.24.71 O Peptidase family M13
HPBIMMBF_01230 2.1e-82 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPBIMMBF_01231 8.4e-262 nox C NADH oxidase
HPBIMMBF_01232 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HPBIMMBF_01233 8.8e-163 S Cell surface protein
HPBIMMBF_01234 4.7e-115 S WxL domain surface cell wall-binding
HPBIMMBF_01235 6.6e-99 S WxL domain surface cell wall-binding
HPBIMMBF_01236 1.3e-44
HPBIMMBF_01237 1.2e-103 K Bacterial regulatory proteins, tetR family
HPBIMMBF_01238 1.5e-49
HPBIMMBF_01239 6.4e-246 S Putative metallopeptidase domain
HPBIMMBF_01240 9.2e-220 3.1.3.1 S associated with various cellular activities
HPBIMMBF_01241 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HPBIMMBF_01242 0.0 ubiB S ABC1 family
HPBIMMBF_01243 1.3e-249 brnQ U Component of the transport system for branched-chain amino acids
HPBIMMBF_01244 0.0 lacS G Transporter
HPBIMMBF_01245 0.0 lacA 3.2.1.23 G -beta-galactosidase
HPBIMMBF_01246 9.6e-135 lacR K Transcriptional regulator
HPBIMMBF_01247 7.2e-17
HPBIMMBF_01248 5.2e-15
HPBIMMBF_01249 1.9e-18
HPBIMMBF_01250 1.6e-16
HPBIMMBF_01251 2.4e-311 msbA2 3.6.3.44 P ABC transporter transmembrane region
HPBIMMBF_01252 1.6e-272 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HPBIMMBF_01253 0.0 macB3 V ABC transporter, ATP-binding protein
HPBIMMBF_01254 6.8e-24
HPBIMMBF_01255 5.7e-258 pgi 5.3.1.9 G Belongs to the GPI family
HPBIMMBF_01256 9.7e-155 glcU U sugar transport
HPBIMMBF_01257 3.2e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HPBIMMBF_01258 1.2e-285 yclK 2.7.13.3 T Histidine kinase
HPBIMMBF_01259 1.6e-134 K response regulator
HPBIMMBF_01260 3e-243 XK27_08635 S UPF0210 protein
HPBIMMBF_01261 8.9e-38 gcvR T Belongs to the UPF0237 family
HPBIMMBF_01262 6.4e-168 EG EamA-like transporter family
HPBIMMBF_01264 1.8e-263 V ABC transporter permease
HPBIMMBF_01265 2.4e-90 V ABC transporter, ATP-binding protein
HPBIMMBF_01266 1.6e-58 K Transcriptional regulator C-terminal region
HPBIMMBF_01267 7.7e-92 S ECF-type riboflavin transporter, S component
HPBIMMBF_01268 8.6e-48
HPBIMMBF_01269 1e-179 yceI EGP Major facilitator Superfamily
HPBIMMBF_01270 1.3e-16 yceI EGP Major facilitator Superfamily
HPBIMMBF_01271 3.2e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
HPBIMMBF_01272 3.8e-23
HPBIMMBF_01274 1.7e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_01275 1.7e-170 ykfC 3.4.14.13 M NlpC/P60 family
HPBIMMBF_01276 2.1e-79 K AsnC family
HPBIMMBF_01277 7.6e-35
HPBIMMBF_01278 1.5e-33
HPBIMMBF_01279 5.2e-215 2.7.7.65 T diguanylate cyclase
HPBIMMBF_01280 1.3e-295 S ABC transporter, ATP-binding protein
HPBIMMBF_01281 2e-106 3.2.2.20 K acetyltransferase
HPBIMMBF_01282 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPBIMMBF_01283 2.3e-38
HPBIMMBF_01284 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HPBIMMBF_01285 1.4e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPBIMMBF_01286 9.8e-39 L Transposase and inactivated derivatives
HPBIMMBF_01287 4.3e-74 K UTRA domain
HPBIMMBF_01288 3.2e-152 estA S Putative esterase
HPBIMMBF_01289 1.3e-58
HPBIMMBF_01290 3.7e-200 EGP Major Facilitator Superfamily
HPBIMMBF_01291 4.7e-168 K Transcriptional regulator, LysR family
HPBIMMBF_01292 2.1e-165 G Xylose isomerase-like TIM barrel
HPBIMMBF_01293 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
HPBIMMBF_01294 3.6e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPBIMMBF_01295 2.5e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPBIMMBF_01296 1.6e-172 ydiN EGP Major Facilitator Superfamily
HPBIMMBF_01297 4e-35 ydiN EGP Major Facilitator Superfamily
HPBIMMBF_01298 2.7e-174 K Transcriptional regulator, LysR family
HPBIMMBF_01299 2.4e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPBIMMBF_01300 1.7e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HPBIMMBF_01301 1e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPBIMMBF_01302 0.0 1.3.5.4 C FAD binding domain
HPBIMMBF_01303 2.9e-63 S pyridoxamine 5-phosphate
HPBIMMBF_01304 1.5e-45 C Aldo keto reductase family protein
HPBIMMBF_01305 1.4e-136 C Aldo keto reductase family protein
HPBIMMBF_01306 3.4e-175 galR K Transcriptional regulator
HPBIMMBF_01307 3.2e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPBIMMBF_01308 0.0 lacS G Transporter
HPBIMMBF_01309 3.6e-57 rafA 3.2.1.22 G alpha-galactosidase
HPBIMMBF_01310 0.0 rafA 3.2.1.22 G alpha-galactosidase
HPBIMMBF_01311 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HPBIMMBF_01312 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HPBIMMBF_01313 3.5e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPBIMMBF_01314 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPBIMMBF_01315 4.7e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HPBIMMBF_01316 3.2e-181 galR K Transcriptional regulator
HPBIMMBF_01317 2e-63 K Helix-turn-helix XRE-family like proteins
HPBIMMBF_01318 9.6e-93 fic D Fic/DOC family
HPBIMMBF_01319 3.1e-181 rhaR K helix_turn_helix, arabinose operon control protein
HPBIMMBF_01320 1.2e-230 EGP Major facilitator Superfamily
HPBIMMBF_01321 5.2e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPBIMMBF_01322 2.2e-74 mdtH P Sugar (and other) transporter
HPBIMMBF_01323 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_01324 2.4e-78 ndh 1.6.99.3 C NADH dehydrogenase
HPBIMMBF_01325 2.3e-270 ndh 1.6.99.3 C NADH dehydrogenase
HPBIMMBF_01326 4.2e-86 ynhH S NusG domain II
HPBIMMBF_01327 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HPBIMMBF_01328 3.8e-179 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPBIMMBF_01329 2.1e-61 rplQ J Ribosomal protein L17
HPBIMMBF_01330 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPBIMMBF_01331 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPBIMMBF_01332 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPBIMMBF_01333 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPBIMMBF_01334 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPBIMMBF_01335 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPBIMMBF_01336 6.3e-70 rplO J Binds to the 23S rRNA
HPBIMMBF_01337 2.2e-24 rpmD J Ribosomal protein L30
HPBIMMBF_01338 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPBIMMBF_01339 2.1e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPBIMMBF_01340 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPBIMMBF_01341 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPBIMMBF_01342 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPBIMMBF_01343 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPBIMMBF_01344 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPBIMMBF_01345 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPBIMMBF_01346 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HPBIMMBF_01347 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPBIMMBF_01348 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPBIMMBF_01349 8.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPBIMMBF_01350 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPBIMMBF_01351 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPBIMMBF_01352 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPBIMMBF_01353 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HPBIMMBF_01354 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPBIMMBF_01355 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HPBIMMBF_01356 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPBIMMBF_01357 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPBIMMBF_01358 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPBIMMBF_01359 5.6e-113 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HPBIMMBF_01360 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPBIMMBF_01361 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPBIMMBF_01362 1.5e-109 K Bacterial regulatory proteins, tetR family
HPBIMMBF_01363 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPBIMMBF_01364 6.9e-78 ctsR K Belongs to the CtsR family
HPBIMMBF_01372 4.5e-49 ndoA L Toxic component of a toxin-antitoxin (TA) module
HPBIMMBF_01373 5.7e-54 kup P Transport of potassium into the cell
HPBIMMBF_01374 1.4e-300 kup P Transport of potassium into the cell
HPBIMMBF_01375 1.4e-192 P ABC transporter, substratebinding protein
HPBIMMBF_01376 6.3e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
HPBIMMBF_01377 5e-134 P ATPases associated with a variety of cellular activities
HPBIMMBF_01378 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPBIMMBF_01379 4.8e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPBIMMBF_01381 5.5e-161 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPBIMMBF_01382 1e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPBIMMBF_01383 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HPBIMMBF_01384 9.3e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HPBIMMBF_01385 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPBIMMBF_01386 4.1e-84 S QueT transporter
HPBIMMBF_01387 2.1e-114 S (CBS) domain
HPBIMMBF_01388 6.4e-265 S Putative peptidoglycan binding domain
HPBIMMBF_01389 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPBIMMBF_01390 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPBIMMBF_01391 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPBIMMBF_01392 9.6e-289 yabM S Polysaccharide biosynthesis protein
HPBIMMBF_01393 2.2e-42 yabO J S4 domain protein
HPBIMMBF_01395 4.1e-63 divIC D Septum formation initiator
HPBIMMBF_01396 3.1e-74 yabR J RNA binding
HPBIMMBF_01397 2.2e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPBIMMBF_01398 1.4e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPBIMMBF_01399 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPBIMMBF_01400 7.7e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPBIMMBF_01401 3.3e-186 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPBIMMBF_01402 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HPBIMMBF_01403 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_01404 6.8e-96 P Sodium:sulfate symporter transmembrane region
HPBIMMBF_01405 3.1e-156 K LysR family
HPBIMMBF_01406 1e-72 C FMN binding
HPBIMMBF_01407 3.2e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPBIMMBF_01408 1.7e-162 ptlF S KR domain
HPBIMMBF_01409 7.1e-158 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HPBIMMBF_01410 7.7e-114 drgA C Nitroreductase family
HPBIMMBF_01411 4.1e-289 QT PucR C-terminal helix-turn-helix domain
HPBIMMBF_01412 6.1e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HPBIMMBF_01413 2.5e-194 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPBIMMBF_01414 7.4e-250 yjjP S Putative threonine/serine exporter
HPBIMMBF_01415 1.7e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
HPBIMMBF_01416 2e-79 6.3.3.2 S ASCH
HPBIMMBF_01417 5.5e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HPBIMMBF_01418 1.5e-169 yobV1 K WYL domain
HPBIMMBF_01419 1e-116 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPBIMMBF_01420 0.0 tetP J elongation factor G
HPBIMMBF_01421 9.9e-126 S Protein of unknown function
HPBIMMBF_01422 4.7e-152 EG EamA-like transporter family
HPBIMMBF_01423 2.2e-90 MA20_25245 K FR47-like protein
HPBIMMBF_01424 9.7e-126 hchA S DJ-1/PfpI family
HPBIMMBF_01425 6.8e-184 1.1.1.1 C nadph quinone reductase
HPBIMMBF_01426 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPBIMMBF_01427 5.1e-235 mepA V MATE efflux family protein
HPBIMMBF_01428 3.6e-168 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HPBIMMBF_01429 2.9e-139 S Belongs to the UPF0246 family
HPBIMMBF_01430 6e-76
HPBIMMBF_01431 5.5e-308 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HPBIMMBF_01432 4.5e-140
HPBIMMBF_01434 5.6e-141 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HPBIMMBF_01435 4.8e-40
HPBIMMBF_01436 7.8e-129 cbiO P ABC transporter
HPBIMMBF_01437 2.6e-149 P Cobalt transport protein
HPBIMMBF_01438 6.3e-182 nikMN P PDGLE domain
HPBIMMBF_01439 4.2e-121 K Crp-like helix-turn-helix domain
HPBIMMBF_01440 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HPBIMMBF_01441 9.1e-122 larB S AIR carboxylase
HPBIMMBF_01442 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HPBIMMBF_01443 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
HPBIMMBF_01444 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPBIMMBF_01445 1.1e-150 larE S NAD synthase
HPBIMMBF_01446 2.3e-176 1.6.5.5 C Zinc-binding dehydrogenase
HPBIMMBF_01447 1.1e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPBIMMBF_01448 9.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HPBIMMBF_01449 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HPBIMMBF_01450 1.7e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HPBIMMBF_01451 6e-137 S peptidase C26
HPBIMMBF_01452 6.6e-176 L HIRAN domain
HPBIMMBF_01453 5.9e-107 L HIRAN domain
HPBIMMBF_01454 1.7e-84 F NUDIX domain
HPBIMMBF_01455 2.6e-250 yifK E Amino acid permease
HPBIMMBF_01456 4.4e-121
HPBIMMBF_01457 1.1e-149 ydjP I Alpha/beta hydrolase family
HPBIMMBF_01458 0.0 pacL1 P P-type ATPase
HPBIMMBF_01459 3.5e-28 KT PspC domain
HPBIMMBF_01460 3.3e-109 S NADPH-dependent FMN reductase
HPBIMMBF_01461 1.8e-73 papX3 K Transcriptional regulator
HPBIMMBF_01462 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
HPBIMMBF_01463 3.2e-80 S Protein of unknown function (DUF3021)
HPBIMMBF_01464 3e-66 K LytTr DNA-binding domain
HPBIMMBF_01465 1.4e-226 mdtG EGP Major facilitator Superfamily
HPBIMMBF_01466 3.3e-50 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPBIMMBF_01467 8.9e-215 yeaN P Transporter, major facilitator family protein
HPBIMMBF_01469 1.8e-156 S reductase
HPBIMMBF_01470 2.1e-34 1.1.1.65 C Aldo keto reductase
HPBIMMBF_01471 2.5e-115 1.1.1.65 C Aldo keto reductase
HPBIMMBF_01472 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HPBIMMBF_01473 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HPBIMMBF_01474 5.2e-49
HPBIMMBF_01475 3.7e-258
HPBIMMBF_01476 3.7e-207 C Oxidoreductase
HPBIMMBF_01477 4.9e-151 cbiQ P cobalt transport
HPBIMMBF_01478 0.0 ykoD P ABC transporter, ATP-binding protein
HPBIMMBF_01479 2.5e-98 S UPF0397 protein
HPBIMMBF_01481 1.6e-129 K UbiC transcription regulator-associated domain protein
HPBIMMBF_01482 8.3e-54 K Transcriptional regulator PadR-like family
HPBIMMBF_01483 1.9e-141
HPBIMMBF_01484 3.4e-149
HPBIMMBF_01485 9.1e-89
HPBIMMBF_01486 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HPBIMMBF_01487 5.7e-169 yjjC V ABC transporter
HPBIMMBF_01488 2.7e-28 M Exporter of polyketide antibiotics
HPBIMMBF_01489 3.4e-247 M Exporter of polyketide antibiotics
HPBIMMBF_01490 1.1e-116 K Transcriptional regulator
HPBIMMBF_01491 2.2e-274 C Electron transfer flavoprotein FAD-binding domain
HPBIMMBF_01492 3.3e-73 folT 2.7.13.3 T ECF transporter, substrate-specific component
HPBIMMBF_01494 1.9e-92 K Bacterial regulatory proteins, tetR family
HPBIMMBF_01495 3.2e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HPBIMMBF_01496 6.2e-185 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HPBIMMBF_01497 5.5e-101 dhaL 2.7.1.121 S Dak2
HPBIMMBF_01498 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
HPBIMMBF_01499 3.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPBIMMBF_01500 2.2e-190 malR K Transcriptional regulator, LacI family
HPBIMMBF_01501 2e-180 yvdE K helix_turn _helix lactose operon repressor
HPBIMMBF_01502 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HPBIMMBF_01503 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
HPBIMMBF_01504 5.4e-226 malC P Binding-protein-dependent transport system inner membrane component
HPBIMMBF_01505 1.4e-161 malD P ABC transporter permease
HPBIMMBF_01506 5.3e-150 malA S maltodextrose utilization protein MalA
HPBIMMBF_01507 5e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HPBIMMBF_01508 1.5e-208 msmK P Belongs to the ABC transporter superfamily
HPBIMMBF_01509 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HPBIMMBF_01510 0.0 3.2.1.96 G Glycosyl hydrolase family 85
HPBIMMBF_01511 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
HPBIMMBF_01512 2.7e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HPBIMMBF_01513 6.9e-274 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HPBIMMBF_01514 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_01515 1.2e-53 mleP S Sodium Bile acid symporter family
HPBIMMBF_01516 6.7e-102 mleP S Sodium Bile acid symporter family
HPBIMMBF_01517 3.6e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HPBIMMBF_01518 3.7e-148 mleR K LysR family
HPBIMMBF_01519 5.1e-159 mleR K LysR family transcriptional regulator
HPBIMMBF_01520 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HPBIMMBF_01521 2.7e-263 frdC 1.3.5.4 C FAD binding domain
HPBIMMBF_01522 5.4e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HPBIMMBF_01524 2.3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HPBIMMBF_01525 1e-162 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HPBIMMBF_01526 4.4e-43 citD C Covalent carrier of the coenzyme of citrate lyase
HPBIMMBF_01527 6.3e-188 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HPBIMMBF_01528 5.6e-206 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HPBIMMBF_01529 2.3e-176 citR K sugar-binding domain protein
HPBIMMBF_01530 8.3e-260 citP P Sodium:sulfate symporter transmembrane region
HPBIMMBF_01531 2.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPBIMMBF_01532 3.1e-50
HPBIMMBF_01533 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HPBIMMBF_01534 8.2e-141 mtsB U ABC 3 transport family
HPBIMMBF_01535 9.9e-132 mntB 3.6.3.35 P ABC transporter
HPBIMMBF_01536 1.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HPBIMMBF_01537 7.7e-199 K Helix-turn-helix domain
HPBIMMBF_01538 8.3e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
HPBIMMBF_01539 3.5e-114 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
HPBIMMBF_01540 4.1e-53 yitW S Iron-sulfur cluster assembly protein
HPBIMMBF_01541 5.6e-150 P Sodium:sulfate symporter transmembrane region
HPBIMMBF_01542 1.1e-92 P Sodium:sulfate symporter transmembrane region
HPBIMMBF_01544 5.8e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPBIMMBF_01545 6.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
HPBIMMBF_01546 2.8e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPBIMMBF_01547 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPBIMMBF_01548 7.1e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HPBIMMBF_01549 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_01551 1.8e-19 S by MetaGeneAnnotator
HPBIMMBF_01552 3.9e-25 3.4.22.70 M Sortase family
HPBIMMBF_01555 6.8e-126 clpB O Belongs to the ClpA ClpB family
HPBIMMBF_01558 1.6e-33 L Protein of unknown function (DUF3991)
HPBIMMBF_01561 4.2e-104 traI 5.99.1.2 L C-terminal repeat of topoisomerase
HPBIMMBF_01562 1.5e-147 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HPBIMMBF_01564 4.3e-14 XK27_07075 S CAAX protease self-immunity
HPBIMMBF_01565 1.2e-42 ruvB 3.6.4.12 L four-way junction helicase activity
HPBIMMBF_01574 7.3e-34 S Protein of unknown function (DUF3102)
HPBIMMBF_01575 6.1e-13
HPBIMMBF_01576 1.3e-96 M CHAP domain
HPBIMMBF_01578 2.8e-125 U type IV secretory pathway VirB4
HPBIMMBF_01579 5.8e-14
HPBIMMBF_01581 3.6e-27 I mechanosensitive ion channel activity
HPBIMMBF_01582 7.9e-99 K Primase C terminal 1 (PriCT-1)
HPBIMMBF_01583 1.4e-95 D Cellulose biosynthesis protein BcsQ
HPBIMMBF_01584 3.9e-26
HPBIMMBF_01585 9.6e-183 S Oxidoreductase family, NAD-binding Rossmann fold
HPBIMMBF_01586 9e-113 acmA 3.2.1.17 NU mannosyl-glycoprotein
HPBIMMBF_01587 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPBIMMBF_01588 1e-93 S UPF0316 protein
HPBIMMBF_01589 2.5e-217 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPBIMMBF_01590 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HPBIMMBF_01591 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPBIMMBF_01592 2.6e-198 camS S sex pheromone
HPBIMMBF_01593 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPBIMMBF_01594 6.1e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPBIMMBF_01595 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPBIMMBF_01596 1e-190 yegS 2.7.1.107 G Lipid kinase
HPBIMMBF_01597 5.2e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPBIMMBF_01598 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
HPBIMMBF_01599 0.0 yfgQ P E1-E2 ATPase
HPBIMMBF_01600 4.8e-205 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_01601 3.1e-61 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_01602 7e-86 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_01603 4.3e-150 gntR K rpiR family
HPBIMMBF_01604 1.1e-144 lys M Glycosyl hydrolases family 25
HPBIMMBF_01605 4.1e-62 S Domain of unknown function (DUF4828)
HPBIMMBF_01606 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
HPBIMMBF_01607 2.4e-189 mocA S Oxidoreductase
HPBIMMBF_01608 9.9e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
HPBIMMBF_01610 2.3e-75 T Universal stress protein family
HPBIMMBF_01611 1.1e-242 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_01612 5.2e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_01614 1.3e-73
HPBIMMBF_01615 1.2e-105
HPBIMMBF_01616 2.2e-120 C Enoyl-(Acyl carrier protein) reductase
HPBIMMBF_01617 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HPBIMMBF_01618 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HPBIMMBF_01619 2.6e-71 yqeY S YqeY-like protein
HPBIMMBF_01620 1.3e-179 phoH T phosphate starvation-inducible protein PhoH
HPBIMMBF_01621 2.5e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPBIMMBF_01622 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HPBIMMBF_01623 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPBIMMBF_01624 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
HPBIMMBF_01625 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HPBIMMBF_01626 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HPBIMMBF_01627 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPBIMMBF_01628 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPBIMMBF_01629 1e-63 K helix_turn_helix gluconate operon transcriptional repressor
HPBIMMBF_01630 2.2e-165 ytrB V ABC transporter, ATP-binding protein
HPBIMMBF_01631 1.8e-98
HPBIMMBF_01632 2.7e-92
HPBIMMBF_01633 2.2e-69
HPBIMMBF_01634 1.3e-103
HPBIMMBF_01635 3.7e-126 S ABC-2 family transporter protein
HPBIMMBF_01636 1.4e-119 V ABC transporter, ATP-binding protein
HPBIMMBF_01637 1.1e-113 S Psort location CytoplasmicMembrane, score
HPBIMMBF_01638 4.7e-79 K MarR family
HPBIMMBF_01639 1.7e-81 K Acetyltransferase (GNAT) domain
HPBIMMBF_01641 7.4e-158 yvfR V ABC transporter
HPBIMMBF_01642 8.5e-134 yvfS V ABC-2 type transporter
HPBIMMBF_01643 4.7e-202 desK 2.7.13.3 T Histidine kinase
HPBIMMBF_01644 6.1e-103 desR K helix_turn_helix, Lux Regulon
HPBIMMBF_01645 9.7e-269 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPBIMMBF_01646 6.3e-14 S Alpha beta hydrolase
HPBIMMBF_01647 3.3e-172 C nadph quinone reductase
HPBIMMBF_01648 1.6e-160 K Transcriptional regulator
HPBIMMBF_01649 5.4e-77 S Uncharacterized protein conserved in bacteria (DUF2255)
HPBIMMBF_01650 1.5e-112 GM NmrA-like family
HPBIMMBF_01651 8.5e-159 S Alpha beta hydrolase
HPBIMMBF_01652 1.3e-128 K Helix-turn-helix domain, rpiR family
HPBIMMBF_01653 6.5e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HPBIMMBF_01654 1.7e-128 4.1.2.14 S KDGP aldolase
HPBIMMBF_01655 8.8e-201 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
HPBIMMBF_01656 2.1e-210 dho 3.5.2.3 S Amidohydrolase family
HPBIMMBF_01657 5e-212 S Bacterial protein of unknown function (DUF871)
HPBIMMBF_01658 4.7e-39
HPBIMMBF_01659 5.1e-229 pts3C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_01660 3e-122 K helix_turn_helix gluconate operon transcriptional repressor
HPBIMMBF_01661 5.4e-98 yieF S NADPH-dependent FMN reductase
HPBIMMBF_01662 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
HPBIMMBF_01663 3.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
HPBIMMBF_01664 2e-62
HPBIMMBF_01665 4.3e-95
HPBIMMBF_01666 1.2e-49
HPBIMMBF_01667 6.2e-57 trxA1 O Belongs to the thioredoxin family
HPBIMMBF_01668 8.7e-72
HPBIMMBF_01669 4.3e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HPBIMMBF_01670 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_01671 0.0 mtlR K Mga helix-turn-helix domain
HPBIMMBF_01672 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HPBIMMBF_01673 3.9e-278 pipD E Dipeptidase
HPBIMMBF_01675 8.1e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPBIMMBF_01676 3e-69
HPBIMMBF_01677 4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPBIMMBF_01678 2e-157 dkgB S reductase
HPBIMMBF_01679 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HPBIMMBF_01680 3.1e-101 S ABC transporter permease
HPBIMMBF_01681 1.2e-258 P ABC transporter
HPBIMMBF_01682 2.6e-115 P cobalt transport
HPBIMMBF_01683 1.6e-256 S ATPases associated with a variety of cellular activities
HPBIMMBF_01684 5.5e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPBIMMBF_01685 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPBIMMBF_01686 5.1e-104 ropB K Helix-turn-helix XRE-family like proteins
HPBIMMBF_01687 3.9e-24 ropB K Helix-turn-helix XRE-family like proteins
HPBIMMBF_01688 1e-205 EGP Major facilitator Superfamily
HPBIMMBF_01689 0.0 uvrA3 L excinuclease ABC
HPBIMMBF_01690 0.0 S Predicted membrane protein (DUF2207)
HPBIMMBF_01691 8.1e-123 3.1.3.102, 3.1.3.104 S hydrolase
HPBIMMBF_01692 1e-306 ybiT S ABC transporter, ATP-binding protein
HPBIMMBF_01693 9e-223 S CAAX protease self-immunity
HPBIMMBF_01694 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
HPBIMMBF_01695 2e-100 speG J Acetyltransferase (GNAT) domain
HPBIMMBF_01696 4e-141 endA F DNA RNA non-specific endonuclease
HPBIMMBF_01697 4.1e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPBIMMBF_01698 1.7e-108 K Transcriptional regulator (TetR family)
HPBIMMBF_01699 1.6e-198 yhgE V domain protein
HPBIMMBF_01700 6.1e-09
HPBIMMBF_01702 2.4e-243 EGP Major facilitator Superfamily
HPBIMMBF_01703 0.0 mdlA V ABC transporter
HPBIMMBF_01704 0.0 mdlB V ABC transporter
HPBIMMBF_01706 1.7e-193 C Aldo/keto reductase family
HPBIMMBF_01707 5.7e-102 M Protein of unknown function (DUF3737)
HPBIMMBF_01708 1.5e-74 patB 4.4.1.8 E Aminotransferase, class I
HPBIMMBF_01709 5.8e-132 patB 4.4.1.8 E Aminotransferase, class I
HPBIMMBF_01710 1.9e-101 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HPBIMMBF_01712 5.5e-14
HPBIMMBF_01713 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPBIMMBF_01714 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPBIMMBF_01715 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HPBIMMBF_01716 6.6e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPBIMMBF_01717 2e-129 gntR K UTRA
HPBIMMBF_01718 9.9e-140 epsV 2.7.8.12 S glycosyl transferase family 2
HPBIMMBF_01719 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPBIMMBF_01720 1.8e-81
HPBIMMBF_01721 9.8e-152 S hydrolase
HPBIMMBF_01722 3.6e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPBIMMBF_01723 4.1e-151 EG EamA-like transporter family
HPBIMMBF_01724 3.9e-173 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HPBIMMBF_01725 4.3e-98 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HPBIMMBF_01726 1.2e-230
HPBIMMBF_01727 5.5e-77 fld C Flavodoxin
HPBIMMBF_01728 0.0 M Bacterial Ig-like domain (group 3)
HPBIMMBF_01729 5.8e-59 M Bacterial Ig-like domain (group 3)
HPBIMMBF_01730 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HPBIMMBF_01731 2.7e-32
HPBIMMBF_01732 3.3e-125 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
HPBIMMBF_01733 6e-266 ycaM E amino acid
HPBIMMBF_01734 7.9e-79 K Winged helix DNA-binding domain
HPBIMMBF_01735 1.1e-158 S Oxidoreductase, aldo keto reductase family protein
HPBIMMBF_01736 1.4e-161 akr5f 1.1.1.346 S reductase
HPBIMMBF_01737 4.6e-163 K Transcriptional regulator
HPBIMMBF_01739 2.3e-47 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HPBIMMBF_01740 2.3e-53
HPBIMMBF_01741 1.7e-58
HPBIMMBF_01742 8.9e-130 L AAA ATPase domain
HPBIMMBF_01743 7.8e-66 3.6.4.12 L UvrD/REP helicase N-terminal domain
HPBIMMBF_01744 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HPBIMMBF_01745 2.6e-302 hsdM 2.1.1.72 V type I restriction-modification system
HPBIMMBF_01746 9.3e-90 3.1.21.3 V Type I restriction modification DNA specificity domain
HPBIMMBF_01747 1.5e-192 L Psort location Cytoplasmic, score
HPBIMMBF_01748 2.9e-31
HPBIMMBF_01749 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HPBIMMBF_01750 1.8e-66
HPBIMMBF_01751 1.9e-150
HPBIMMBF_01752 1.3e-61
HPBIMMBF_01753 2.7e-269 traK U COG3505 Type IV secretory pathway, VirD4 components
HPBIMMBF_01754 3.9e-81
HPBIMMBF_01755 6.6e-60 CO COG0526, thiol-disulfide isomerase and thioredoxins
HPBIMMBF_01756 3.2e-83
HPBIMMBF_01757 1.7e-194 M CHAP domain
HPBIMMBF_01758 7.6e-221 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HPBIMMBF_01759 0.0 traE U type IV secretory pathway VirB4
HPBIMMBF_01760 6.2e-117
HPBIMMBF_01761 7.8e-37
HPBIMMBF_01762 6.1e-52 S Cag pathogenicity island, type IV secretory system
HPBIMMBF_01763 3.3e-104
HPBIMMBF_01764 1.4e-50
HPBIMMBF_01765 7.8e-211 traA L MobA MobL family protein
HPBIMMBF_01766 4.6e-54 yhcG V ATPases associated with a variety of cellular activities
HPBIMMBF_01768 2.5e-91 L PFAM Integrase, catalytic core
HPBIMMBF_01769 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPBIMMBF_01770 8.8e-128 ybbR S YbbR-like protein
HPBIMMBF_01771 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPBIMMBF_01772 7.1e-121 S Protein of unknown function (DUF1361)
HPBIMMBF_01773 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
HPBIMMBF_01774 0.0 yjcE P Sodium proton antiporter
HPBIMMBF_01775 1.8e-167 murB 1.3.1.98 M Cell wall formation
HPBIMMBF_01776 3.8e-157 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HPBIMMBF_01777 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
HPBIMMBF_01778 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
HPBIMMBF_01779 1.8e-87 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HPBIMMBF_01780 1.1e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HPBIMMBF_01781 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HPBIMMBF_01782 4.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPBIMMBF_01783 1.7e-154 ycsE S Sucrose-6F-phosphate phosphohydrolase
HPBIMMBF_01784 3.9e-104 yxjI
HPBIMMBF_01785 3.4e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPBIMMBF_01786 1.5e-256 glnP P ABC transporter
HPBIMMBF_01787 3.1e-117 3.4.21.72 M Bacterial Ig-like domain (group 3)
HPBIMMBF_01788 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
HPBIMMBF_01789 4.3e-69 3.4.21.72 M Bacterial Ig-like domain (group 3)
HPBIMMBF_01790 3.7e-72 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_01791 5.8e-250 cycA E Amino acid permease
HPBIMMBF_01792 1.2e-255 nhaC C Na H antiporter NhaC
HPBIMMBF_01793 1.6e-27 3.2.2.10 S Belongs to the LOG family
HPBIMMBF_01794 1.3e-199 frlB M SIS domain
HPBIMMBF_01795 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HPBIMMBF_01796 1.3e-218 S Uncharacterized protein conserved in bacteria (DUF2325)
HPBIMMBF_01797 9e-124 yyaQ S YjbR
HPBIMMBF_01799 0.0 cadA P P-type ATPase
HPBIMMBF_01800 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
HPBIMMBF_01801 4e-121 E GDSL-like Lipase/Acylhydrolase family
HPBIMMBF_01802 1.4e-77
HPBIMMBF_01803 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
HPBIMMBF_01804 1.2e-63 FG HIT domain
HPBIMMBF_01805 1.2e-171 S Aldo keto reductase
HPBIMMBF_01806 5.6e-52 yitW S Pfam:DUF59
HPBIMMBF_01807 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPBIMMBF_01808 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HPBIMMBF_01809 5e-195 blaA6 V Beta-lactamase
HPBIMMBF_01810 1.8e-95 V VanZ like family
HPBIMMBF_01811 1.6e-21 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HPBIMMBF_01812 3e-306 arlS 2.7.13.3 T Histidine kinase
HPBIMMBF_01813 4.3e-121 K response regulator
HPBIMMBF_01814 3.8e-128 rarA L recombination factor protein RarA
HPBIMMBF_01815 1.2e-103 rarA L recombination factor protein RarA
HPBIMMBF_01816 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPBIMMBF_01817 9.2e-170 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPBIMMBF_01818 6e-87 S Peptidase propeptide and YPEB domain
HPBIMMBF_01819 7.8e-97 yceD S Uncharacterized ACR, COG1399
HPBIMMBF_01820 2.2e-218 ylbM S Belongs to the UPF0348 family
HPBIMMBF_01821 2.9e-139 yqeM Q Methyltransferase
HPBIMMBF_01822 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPBIMMBF_01823 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HPBIMMBF_01824 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPBIMMBF_01825 1.1e-50 yhbY J RNA-binding protein
HPBIMMBF_01826 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
HPBIMMBF_01827 4e-98 yqeG S HAD phosphatase, family IIIA
HPBIMMBF_01828 1.3e-79
HPBIMMBF_01829 9.4e-133 pgaC GT2 M Glycosyl transferase
HPBIMMBF_01830 4.8e-99 pgaC GT2 M Glycosyl transferase
HPBIMMBF_01831 5e-41 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HPBIMMBF_01832 9e-62 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HPBIMMBF_01833 2.3e-62 hxlR K Transcriptional regulator, HxlR family
HPBIMMBF_01834 6.1e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPBIMMBF_01835 5e-240 yrvN L AAA C-terminal domain
HPBIMMBF_01836 5.2e-17
HPBIMMBF_01839 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPBIMMBF_01840 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HPBIMMBF_01841 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPBIMMBF_01842 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPBIMMBF_01843 3.3e-172 dnaI L Primosomal protein DnaI
HPBIMMBF_01844 6.1e-247 dnaB L replication initiation and membrane attachment
HPBIMMBF_01845 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPBIMMBF_01846 1.1e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPBIMMBF_01847 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPBIMMBF_01848 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPBIMMBF_01849 1.3e-120 ybhL S Belongs to the BI1 family
HPBIMMBF_01850 1.7e-28 yozG K Transcriptional regulator
HPBIMMBF_01851 2.2e-88 S Protein of unknown function (DUF2975)
HPBIMMBF_01852 3.1e-74
HPBIMMBF_01853 2.5e-175
HPBIMMBF_01854 6.7e-122 narI 1.7.5.1 C Nitrate reductase
HPBIMMBF_01855 5.6e-98 narJ C Nitrate reductase delta subunit
HPBIMMBF_01856 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HPBIMMBF_01857 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HPBIMMBF_01858 2.7e-191 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HPBIMMBF_01859 5.4e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HPBIMMBF_01860 3.8e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HPBIMMBF_01861 1.1e-86 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HPBIMMBF_01862 4.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HPBIMMBF_01863 1e-97 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HPBIMMBF_01864 7.8e-39
HPBIMMBF_01865 1.3e-75 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
HPBIMMBF_01866 8.6e-190 comP 2.7.13.3 F Sensor histidine kinase
HPBIMMBF_01867 2.3e-116 nreC K PFAM regulatory protein LuxR
HPBIMMBF_01868 1.5e-49
HPBIMMBF_01869 2.1e-182
HPBIMMBF_01870 1.7e-154 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HPBIMMBF_01871 3.1e-156 hipB K Helix-turn-helix
HPBIMMBF_01872 8.8e-59 yitW S Iron-sulfur cluster assembly protein
HPBIMMBF_01873 4.4e-214 narK P Transporter, major facilitator family protein
HPBIMMBF_01874 6.6e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HPBIMMBF_01875 5.4e-34 moaD 2.8.1.12 H ThiS family
HPBIMMBF_01876 5.2e-69 moaE 2.8.1.12 H MoaE protein
HPBIMMBF_01877 2.9e-81 fld C NrdI Flavodoxin like
HPBIMMBF_01878 8.4e-166 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPBIMMBF_01879 3.7e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HPBIMMBF_01880 2e-173 fecB P Periplasmic binding protein
HPBIMMBF_01881 7.2e-272 sufB O assembly protein SufB
HPBIMMBF_01882 4.6e-82 nifU C SUF system FeS assembly protein, NifU family
HPBIMMBF_01883 1.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPBIMMBF_01884 2.6e-244 sufD O FeS assembly protein SufD
HPBIMMBF_01885 3.6e-143 sufC O FeS assembly ATPase SufC
HPBIMMBF_01886 1.3e-34 feoA P FeoA domain
HPBIMMBF_01887 4.2e-141 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HPBIMMBF_01888 1.2e-216 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HPBIMMBF_01889 1.5e-19 S Virus attachment protein p12 family
HPBIMMBF_01890 3.7e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HPBIMMBF_01891 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HPBIMMBF_01892 6.2e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPBIMMBF_01893 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
HPBIMMBF_01894 1.7e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPBIMMBF_01895 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HPBIMMBF_01896 3.1e-223 ecsB U ABC transporter
HPBIMMBF_01897 2.4e-133 ecsA V ABC transporter, ATP-binding protein
HPBIMMBF_01898 9.9e-82 hit FG histidine triad
HPBIMMBF_01899 3e-46
HPBIMMBF_01900 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPBIMMBF_01901 2.3e-77 S WxL domain surface cell wall-binding
HPBIMMBF_01902 4.4e-102 S WxL domain surface cell wall-binding
HPBIMMBF_01903 1e-190 S Fn3-like domain
HPBIMMBF_01904 2.8e-58
HPBIMMBF_01905 1.3e-77
HPBIMMBF_01906 0.0
HPBIMMBF_01907 2e-239 npr 1.11.1.1 C NADH oxidase
HPBIMMBF_01908 7.4e-112 K Bacterial regulatory proteins, tetR family
HPBIMMBF_01909 1.6e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HPBIMMBF_01910 1.4e-106
HPBIMMBF_01911 5.8e-64 qorB 1.6.5.2 GM NmrA-like family
HPBIMMBF_01912 1.1e-42 K transcriptional regulator
HPBIMMBF_01913 1.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPBIMMBF_01914 9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HPBIMMBF_01915 1e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HPBIMMBF_01916 4.1e-171 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPBIMMBF_01917 0.0 S membrane
HPBIMMBF_01918 2.1e-17 S NUDIX domain
HPBIMMBF_01919 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPBIMMBF_01920 5.5e-95 ykoT GT2 M Glycosyl transferase family 2
HPBIMMBF_01921 1.5e-68 ykoT GT2 M Glycosyl transferase family 2
HPBIMMBF_01922 2e-240 M domain protein
HPBIMMBF_01923 4.9e-109 V CAAX protease self-immunity
HPBIMMBF_01924 1.8e-114 S CAAX protease self-immunity
HPBIMMBF_01925 3.8e-34 S RelE-like toxin of type II toxin-antitoxin system HigB
HPBIMMBF_01926 6.7e-47 higA K Helix-turn-helix XRE-family like proteins
HPBIMMBF_01927 0.0 helD 3.6.4.12 L DNA helicase
HPBIMMBF_01928 3.8e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HPBIMMBF_01929 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPBIMMBF_01930 9e-130 K UbiC transcription regulator-associated domain protein
HPBIMMBF_01931 9.1e-195 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_01932 4.4e-43 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_01933 3.9e-24
HPBIMMBF_01934 1.7e-75 S Domain of unknown function (DUF3284)
HPBIMMBF_01935 1.5e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_01936 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPBIMMBF_01937 5e-162 GK ROK family
HPBIMMBF_01938 4.1e-133 K Helix-turn-helix domain, rpiR family
HPBIMMBF_01939 3.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPBIMMBF_01940 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HPBIMMBF_01941 2.9e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HPBIMMBF_01942 2.7e-177
HPBIMMBF_01943 4.3e-132 cobB K SIR2 family
HPBIMMBF_01944 7.6e-140 yunF F Protein of unknown function DUF72
HPBIMMBF_01945 4e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
HPBIMMBF_01946 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPBIMMBF_01947 3e-301 ytgP S Polysaccharide biosynthesis protein
HPBIMMBF_01948 3.9e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPBIMMBF_01949 4.1e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPBIMMBF_01950 4.9e-273 pepV 3.5.1.18 E dipeptidase PepV
HPBIMMBF_01951 8.7e-55 uspA T Belongs to the universal stress protein A family
HPBIMMBF_01952 1.7e-199 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HPBIMMBF_01953 1.2e-172 ugpA U Binding-protein-dependent transport system inner membrane component
HPBIMMBF_01954 7.1e-150 ugpE G ABC transporter permease
HPBIMMBF_01955 4.2e-261 ugpB G Bacterial extracellular solute-binding protein
HPBIMMBF_01956 5.6e-121 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HPBIMMBF_01957 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
HPBIMMBF_01958 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPBIMMBF_01959 3.8e-182 XK27_06930 V domain protein
HPBIMMBF_01961 6.5e-123 V Transport permease protein
HPBIMMBF_01962 8e-157 V ABC transporter
HPBIMMBF_01963 4.4e-175 K LytTr DNA-binding domain
HPBIMMBF_01965 2.5e-152 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPBIMMBF_01966 1.6e-64 K helix_turn_helix, mercury resistance
HPBIMMBF_01967 1.3e-16 GM NAD(P)H-binding
HPBIMMBF_01968 2.1e-22 GM NAD(P)H-binding
HPBIMMBF_01969 9.9e-48 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HPBIMMBF_01970 1.1e-81 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HPBIMMBF_01971 6.1e-146 S Sucrose-6F-phosphate phosphohydrolase
HPBIMMBF_01972 1.7e-108
HPBIMMBF_01973 5.8e-34
HPBIMMBF_01975 4.7e-160 IQ KR domain
HPBIMMBF_01976 4.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
HPBIMMBF_01977 2.5e-40
HPBIMMBF_01978 7.2e-51 XK27_09600 V ABC transporter, ATP-binding protein
HPBIMMBF_01979 4.9e-249 XK27_09600 V ABC transporter, ATP-binding protein
HPBIMMBF_01980 0.0 V ABC transporter
HPBIMMBF_01981 7.3e-217 ykiI
HPBIMMBF_01982 2.6e-115 GM NAD(P)H-binding
HPBIMMBF_01983 1.8e-136 IQ reductase
HPBIMMBF_01984 3.7e-60 I sulfurtransferase activity
HPBIMMBF_01985 2.7e-78 yphH S Cupin domain
HPBIMMBF_01986 3.4e-35 S Phosphatidylethanolamine-binding protein
HPBIMMBF_01987 1.6e-117 GM NAD(P)H-binding
HPBIMMBF_01988 5.3e-174 C C4-dicarboxylate transmembrane transporter activity
HPBIMMBF_01989 8.4e-173 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPBIMMBF_01990 2.6e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
HPBIMMBF_01991 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HPBIMMBF_01992 1.2e-73 S Psort location Cytoplasmic, score
HPBIMMBF_01993 1.3e-207 T diguanylate cyclase
HPBIMMBF_01994 3.8e-119 tag 3.2.2.20 L Methyladenine glycosylase
HPBIMMBF_01995 2.1e-79
HPBIMMBF_01996 2.7e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
HPBIMMBF_01997 6.7e-54 nudA S ASCH
HPBIMMBF_01998 2.2e-78 S SdpI/YhfL protein family
HPBIMMBF_01999 2.8e-93 M Lysin motif
HPBIMMBF_02000 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02001 7.2e-223 pltK 2.7.13.3 T GHKL domain
HPBIMMBF_02002 5.7e-138 pltR K LytTr DNA-binding domain
HPBIMMBF_02003 4.5e-55
HPBIMMBF_02004 2.5e-59
HPBIMMBF_02005 2.5e-113 S CAAX protease self-immunity
HPBIMMBF_02006 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
HPBIMMBF_02007 1.3e-90
HPBIMMBF_02008 2.5e-46
HPBIMMBF_02009 6.3e-265 uvrA2 L ABC transporter
HPBIMMBF_02010 9.1e-164 uvrA2 L ABC transporter
HPBIMMBF_02013 1e-56
HPBIMMBF_02014 3.5e-10
HPBIMMBF_02015 2.1e-180
HPBIMMBF_02016 1.9e-89 gtcA S Teichoic acid glycosylation protein
HPBIMMBF_02017 3.6e-58 S Protein of unknown function (DUF1516)
HPBIMMBF_02018 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HPBIMMBF_02019 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPBIMMBF_02020 1.4e-303 S Protein conserved in bacteria
HPBIMMBF_02021 2e-227 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HPBIMMBF_02022 5.7e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
HPBIMMBF_02023 3e-173 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
HPBIMMBF_02024 3.9e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HPBIMMBF_02025 4e-46 M Lysin motif
HPBIMMBF_02026 1.2e-53 S CAAX protease self-immunity
HPBIMMBF_02027 1.6e-113 V CAAX protease self-immunity
HPBIMMBF_02028 7.1e-121 yclH V ABC transporter
HPBIMMBF_02029 2.1e-181 yclI V MacB-like periplasmic core domain
HPBIMMBF_02030 1.6e-171 XK27_00720 S Leucine-rich repeat (LRR) protein
HPBIMMBF_02031 4.1e-181 XK27_00720 S Leucine-rich repeat (LRR) protein
HPBIMMBF_02032 3.2e-106 tag 3.2.2.20 L glycosylase
HPBIMMBF_02033 0.0 ydgH S MMPL family
HPBIMMBF_02034 3.1e-104 K transcriptional regulator
HPBIMMBF_02035 7.9e-123 2.7.6.5 S RelA SpoT domain protein
HPBIMMBF_02036 1.3e-47
HPBIMMBF_02037 9.9e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HPBIMMBF_02038 5.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPBIMMBF_02039 2.1e-41
HPBIMMBF_02040 9.9e-57
HPBIMMBF_02041 2.1e-241 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_02042 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
HPBIMMBF_02043 1.8e-49
HPBIMMBF_02044 1.3e-125 K Transcriptional regulatory protein, C terminal
HPBIMMBF_02045 2e-250 T PhoQ Sensor
HPBIMMBF_02046 2.5e-46
HPBIMMBF_02047 1.6e-75 yugI 5.3.1.9 J general stress protein
HPBIMMBF_02048 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPBIMMBF_02049 3e-119 dedA S SNARE-like domain protein
HPBIMMBF_02050 4.6e-117 S Protein of unknown function (DUF1461)
HPBIMMBF_02051 4.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPBIMMBF_02052 1.5e-80 yutD S Protein of unknown function (DUF1027)
HPBIMMBF_02053 2.5e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HPBIMMBF_02054 4.4e-117 S Calcineurin-like phosphoesterase
HPBIMMBF_02055 8.1e-252 cycA E Amino acid permease
HPBIMMBF_02056 5e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPBIMMBF_02057 2.3e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
HPBIMMBF_02059 3.8e-87 S Prokaryotic N-terminal methylation motif
HPBIMMBF_02060 3.1e-11 S Prokaryotic N-terminal methylation motif
HPBIMMBF_02061 2.1e-79 gspG NU general secretion pathway protein
HPBIMMBF_02062 5.5e-43 comGC U competence protein ComGC
HPBIMMBF_02063 1.8e-187 comGB NU type II secretion system
HPBIMMBF_02064 5.6e-175 comGA NU Type II IV secretion system protein
HPBIMMBF_02065 1.8e-159 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPBIMMBF_02066 8.3e-131 yebC K Transcriptional regulatory protein
HPBIMMBF_02067 3.6e-08 S DsrE/DsrF-like family
HPBIMMBF_02068 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HPBIMMBF_02069 7.9e-180 ccpA K catabolite control protein A
HPBIMMBF_02070 3.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPBIMMBF_02071 1.2e-79 K helix_turn_helix, mercury resistance
HPBIMMBF_02072 2.8e-56
HPBIMMBF_02073 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HPBIMMBF_02074 2.6e-158 ykuT M mechanosensitive ion channel
HPBIMMBF_02075 1.4e-113 yvyE 3.4.13.9 S YigZ family
HPBIMMBF_02076 3.1e-256 comFA L Helicase C-terminal domain protein
HPBIMMBF_02077 2.2e-125 comFC S Competence protein
HPBIMMBF_02078 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPBIMMBF_02079 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPBIMMBF_02080 2e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPBIMMBF_02081 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HPBIMMBF_02082 1.5e-132 K response regulator
HPBIMMBF_02083 2.1e-250 phoR 2.7.13.3 T Histidine kinase
HPBIMMBF_02084 1.4e-148 pstS P Phosphate
HPBIMMBF_02085 4.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HPBIMMBF_02086 1.5e-155 pstA P Phosphate transport system permease protein PstA
HPBIMMBF_02087 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPBIMMBF_02088 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPBIMMBF_02089 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
HPBIMMBF_02090 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
HPBIMMBF_02091 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HPBIMMBF_02092 1.3e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPBIMMBF_02093 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPBIMMBF_02094 1.4e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HPBIMMBF_02095 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HPBIMMBF_02096 1.9e-124 yliE T Putative diguanylate phosphodiesterase
HPBIMMBF_02097 1.8e-22 nox C NADH oxidase
HPBIMMBF_02098 3.9e-48 nox C NADH oxidase
HPBIMMBF_02099 2.5e-50 K helix_turn_helix, mercury resistance
HPBIMMBF_02100 8.2e-252 ydiC1 EGP Major facilitator Superfamily
HPBIMMBF_02101 1e-40
HPBIMMBF_02102 5.2e-42
HPBIMMBF_02103 2.8e-114
HPBIMMBF_02104 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HPBIMMBF_02105 4.3e-121 K Bacterial regulatory proteins, tetR family
HPBIMMBF_02106 5.3e-72 K Transcriptional regulator
HPBIMMBF_02107 7.4e-68
HPBIMMBF_02108 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HPBIMMBF_02109 1.4e-144
HPBIMMBF_02110 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HPBIMMBF_02111 3.4e-253 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPBIMMBF_02112 1.9e-93 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPBIMMBF_02113 2.1e-148 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HPBIMMBF_02114 2.3e-148 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HPBIMMBF_02115 2.2e-128 treR K UTRA
HPBIMMBF_02116 2.2e-42
HPBIMMBF_02117 2.8e-42 S Protein of unknown function (DUF2089)
HPBIMMBF_02118 9.5e-141 pnuC H nicotinamide mononucleotide transporter
HPBIMMBF_02119 3.9e-158 map 3.4.11.18 E Methionine Aminopeptidase
HPBIMMBF_02120 2.2e-165 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HPBIMMBF_02121 9.8e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HPBIMMBF_02122 2.7e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HPBIMMBF_02123 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02124 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02125 2e-74 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPBIMMBF_02126 7.6e-149 dicA K Helix-turn-helix domain
HPBIMMBF_02127 3.6e-54
HPBIMMBF_02128 1.4e-158 T Calcineurin-like phosphoesterase superfamily domain
HPBIMMBF_02129 7.4e-64
HPBIMMBF_02130 0.0 P Concanavalin A-like lectin/glucanases superfamily
HPBIMMBF_02131 0.0 yhcA V ABC transporter, ATP-binding protein
HPBIMMBF_02132 4.4e-95 cadD P Cadmium resistance transporter
HPBIMMBF_02133 2.6e-49 K Transcriptional regulator, ArsR family
HPBIMMBF_02134 6e-115 S SNARE associated Golgi protein
HPBIMMBF_02135 1.2e-45
HPBIMMBF_02136 6.8e-72 T Belongs to the universal stress protein A family
HPBIMMBF_02137 1.6e-283 mntH P H( )-stimulated, divalent metal cation uptake system
HPBIMMBF_02138 2.3e-119 K Helix-turn-helix XRE-family like proteins
HPBIMMBF_02139 2.8e-82 gtrA S GtrA-like protein
HPBIMMBF_02140 3.5e-114 zmp3 O Zinc-dependent metalloprotease
HPBIMMBF_02141 7e-33
HPBIMMBF_02143 2e-35 livJ E Receptor family ligand binding region
HPBIMMBF_02144 3e-168 livJ E Receptor family ligand binding region
HPBIMMBF_02145 1.9e-153 livH U Branched-chain amino acid transport system / permease component
HPBIMMBF_02146 8.6e-139 livM E Branched-chain amino acid transport system / permease component
HPBIMMBF_02147 2.4e-33 lytE M LysM domain protein
HPBIMMBF_02148 7.4e-67 gcvH E Glycine cleavage H-protein
HPBIMMBF_02149 2.4e-175 sepS16B
HPBIMMBF_02150 1.3e-131
HPBIMMBF_02151 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HPBIMMBF_02152 2.2e-55
HPBIMMBF_02153 3.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPBIMMBF_02154 3.8e-78 elaA S GNAT family
HPBIMMBF_02155 1.7e-75 K Transcriptional regulator
HPBIMMBF_02156 7.8e-227 ndh 1.6.99.3 C NADH dehydrogenase
HPBIMMBF_02157 1.2e-39
HPBIMMBF_02158 1.5e-205 potD P ABC transporter
HPBIMMBF_02159 1.7e-140 potC P ABC transporter permease
HPBIMMBF_02160 2e-149 potB P ABC transporter permease
HPBIMMBF_02161 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPBIMMBF_02162 5e-96 puuR K Cupin domain
HPBIMMBF_02163 1.6e-82 6.3.3.2 S ASCH
HPBIMMBF_02164 8.7e-84 K GNAT family
HPBIMMBF_02165 2.6e-89 K acetyltransferase
HPBIMMBF_02166 8.1e-22
HPBIMMBF_02167 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HPBIMMBF_02168 2e-163 ytrB V ABC transporter
HPBIMMBF_02169 3.5e-41
HPBIMMBF_02170 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02171 4.8e-235 M Glycosyl transferase family group 2
HPBIMMBF_02172 4.4e-275 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPBIMMBF_02173 1.8e-156 xerD L Phage integrase, N-terminal SAM-like domain
HPBIMMBF_02174 4.2e-32 S YozE SAM-like fold
HPBIMMBF_02175 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPBIMMBF_02176 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HPBIMMBF_02177 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HPBIMMBF_02178 2.5e-175 K Transcriptional regulator
HPBIMMBF_02179 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPBIMMBF_02180 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPBIMMBF_02181 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPBIMMBF_02182 6.4e-170 lacX 5.1.3.3 G Aldose 1-epimerase
HPBIMMBF_02183 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HPBIMMBF_02184 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HPBIMMBF_02185 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HPBIMMBF_02186 9.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HPBIMMBF_02187 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPBIMMBF_02188 2.6e-155 dprA LU DNA protecting protein DprA
HPBIMMBF_02189 4.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPBIMMBF_02190 2.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPBIMMBF_02191 2.6e-227 XK27_05470 E Methionine synthase
HPBIMMBF_02192 3.6e-171 cpsY K Transcriptional regulator, LysR family
HPBIMMBF_02193 1.6e-123 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HPBIMMBF_02194 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
HPBIMMBF_02195 4.3e-251 emrY EGP Major facilitator Superfamily
HPBIMMBF_02196 8.6e-260 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HPBIMMBF_02197 3.4e-35 yozE S Belongs to the UPF0346 family
HPBIMMBF_02198 2e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HPBIMMBF_02199 2.8e-147 ypmR E GDSL-like Lipase/Acylhydrolase
HPBIMMBF_02200 3.9e-60 DegV S EDD domain protein, DegV family
HPBIMMBF_02201 4.9e-67 DegV S EDD domain protein, DegV family
HPBIMMBF_02202 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPBIMMBF_02203 2.3e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPBIMMBF_02204 0.0 yfmR S ABC transporter, ATP-binding protein
HPBIMMBF_02205 6.2e-84
HPBIMMBF_02206 8e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPBIMMBF_02207 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPBIMMBF_02208 4.2e-130 3.1.3.102, 3.1.3.104 S hydrolase
HPBIMMBF_02209 5.6e-215 S Tetratricopeptide repeat protein
HPBIMMBF_02210 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPBIMMBF_02211 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HPBIMMBF_02212 2.2e-211 rpsA 1.17.7.4 J Ribosomal protein S1
HPBIMMBF_02213 7.1e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HPBIMMBF_02214 2e-19 M Lysin motif
HPBIMMBF_02215 1.8e-270 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HPBIMMBF_02216 9.9e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
HPBIMMBF_02217 2.9e-48 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPBIMMBF_02218 2e-33 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPBIMMBF_02219 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPBIMMBF_02220 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPBIMMBF_02221 8.2e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPBIMMBF_02222 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPBIMMBF_02223 1.1e-164 xerD D recombinase XerD
HPBIMMBF_02224 1.1e-169 cvfB S S1 domain
HPBIMMBF_02225 4.5e-74 yeaL S Protein of unknown function (DUF441)
HPBIMMBF_02226 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HPBIMMBF_02227 8e-185 L PFAM Integrase, catalytic core
HPBIMMBF_02228 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPBIMMBF_02229 0.0 dnaE 2.7.7.7 L DNA polymerase
HPBIMMBF_02230 8.1e-28 S Protein of unknown function (DUF2929)
HPBIMMBF_02231 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPBIMMBF_02232 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPBIMMBF_02233 8.5e-198 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPBIMMBF_02234 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HPBIMMBF_02235 7.4e-217 M O-Antigen ligase
HPBIMMBF_02236 1.3e-118 drrB U ABC-2 type transporter
HPBIMMBF_02237 1.7e-120 drrA V ABC transporter
HPBIMMBF_02238 1.8e-34 drrA V ABC transporter
HPBIMMBF_02239 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
HPBIMMBF_02240 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HPBIMMBF_02241 8.8e-39 P Rhodanese Homology Domain
HPBIMMBF_02242 8.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
HPBIMMBF_02243 3.3e-206
HPBIMMBF_02244 6.5e-38 I transferase activity, transferring acyl groups other than amino-acyl groups
HPBIMMBF_02245 4.5e-180 C Zinc-binding dehydrogenase
HPBIMMBF_02246 7.2e-130 3.6.3.6 P Cation transporter/ATPase, N-terminus
HPBIMMBF_02247 1.1e-262 3.6.3.6 P Cation transporter/ATPase, N-terminus
HPBIMMBF_02248 1.2e-58 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPBIMMBF_02249 3.2e-141 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPBIMMBF_02250 9.4e-224 EGP Major facilitator Superfamily
HPBIMMBF_02251 4.3e-77 K Transcriptional regulator
HPBIMMBF_02252 1.4e-170 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HPBIMMBF_02253 1.2e-29 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HPBIMMBF_02254 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPBIMMBF_02255 6.8e-136 K DeoR C terminal sensor domain
HPBIMMBF_02256 1.7e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HPBIMMBF_02257 1.5e-21
HPBIMMBF_02258 4.4e-113 XK27_07075 V CAAX protease self-immunity
HPBIMMBF_02259 1.1e-56 hxlR K HxlR-like helix-turn-helix
HPBIMMBF_02260 1.6e-230 EGP Major facilitator Superfamily
HPBIMMBF_02261 1.5e-27 S Cysteine-rich secretory protein family
HPBIMMBF_02262 1.6e-155 S Cysteine-rich secretory protein family
HPBIMMBF_02263 2e-49 K Cro/C1-type HTH DNA-binding domain
HPBIMMBF_02265 4.8e-70 D nuclear chromosome segregation
HPBIMMBF_02266 1.5e-58
HPBIMMBF_02267 2.8e-117 S Domain of unknown function (DUF4767)
HPBIMMBF_02268 1.9e-41
HPBIMMBF_02269 2.2e-37 S MORN repeat
HPBIMMBF_02270 0.0 XK27_09800 I Acyltransferase family
HPBIMMBF_02271 7.1e-37 S Transglycosylase associated protein
HPBIMMBF_02272 1.3e-83
HPBIMMBF_02273 7.2e-23
HPBIMMBF_02274 8.7e-72 asp S Asp23 family, cell envelope-related function
HPBIMMBF_02275 5.3e-72 asp2 S Asp23 family, cell envelope-related function
HPBIMMBF_02276 3.5e-29 2.3.1.128 J Acetyltransferase (GNAT) domain
HPBIMMBF_02277 8e-76 Q Fumarylacetoacetate (FAA) hydrolase family
HPBIMMBF_02278 1.4e-56 Q Fumarylacetoacetate (FAA) hydrolase family
HPBIMMBF_02279 2.2e-161 yjdB S Domain of unknown function (DUF4767)
HPBIMMBF_02280 6.4e-126
HPBIMMBF_02281 1.1e-184 S DUF218 domain
HPBIMMBF_02282 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPBIMMBF_02283 1.1e-147 bla1 3.5.2.6 V Beta-lactamase enzyme family
HPBIMMBF_02284 4.6e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPBIMMBF_02285 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HPBIMMBF_02286 3.5e-31
HPBIMMBF_02287 2.4e-42 ankB S ankyrin repeats
HPBIMMBF_02289 9.2e-131 znuB U ABC 3 transport family
HPBIMMBF_02290 3.7e-128 fhuC 3.6.3.35 P ABC transporter
HPBIMMBF_02291 8.3e-30 S Prolyl oligopeptidase family
HPBIMMBF_02292 5.5e-107 S Prolyl oligopeptidase family
HPBIMMBF_02293 2.9e-162 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPBIMMBF_02294 3.2e-37 veg S Biofilm formation stimulator VEG
HPBIMMBF_02295 1.8e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPBIMMBF_02296 5.1e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPBIMMBF_02297 9.8e-146 tatD L hydrolase, TatD family
HPBIMMBF_02299 1.7e-106 mutR K sequence-specific DNA binding
HPBIMMBF_02300 5.4e-212 bcr1 EGP Major facilitator Superfamily
HPBIMMBF_02301 4.1e-81 S Bacterial protein of unknown function (DUF916)
HPBIMMBF_02302 0.0
HPBIMMBF_02303 6e-161 ypuA S Protein of unknown function (DUF1002)
HPBIMMBF_02304 5.5e-50 yvlA
HPBIMMBF_02305 1.2e-95 K transcriptional regulator
HPBIMMBF_02306 5.1e-90 ymdB S Macro domain protein
HPBIMMBF_02307 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPBIMMBF_02308 2.3e-43 S Protein of unknown function (DUF1093)
HPBIMMBF_02309 2.6e-77 S Threonine/Serine exporter, ThrE
HPBIMMBF_02310 9.2e-133 thrE S Putative threonine/serine exporter
HPBIMMBF_02311 4.4e-163 yvgN C Aldo keto reductase
HPBIMMBF_02312 5.4e-151 ywkB S Membrane transport protein
HPBIMMBF_02313 2.1e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HPBIMMBF_02314 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HPBIMMBF_02315 8.5e-84 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HPBIMMBF_02316 2e-77 M1-874 K Domain of unknown function (DUF1836)
HPBIMMBF_02317 2e-180 D Alpha beta
HPBIMMBF_02318 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HPBIMMBF_02319 1.2e-280 thrC 4.2.3.1 E Threonine synthase
HPBIMMBF_02320 2.5e-144 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HPBIMMBF_02321 1.7e-10 mcbG S Pentapeptide repeats (8 copies)
HPBIMMBF_02322 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPBIMMBF_02323 3.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
HPBIMMBF_02324 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
HPBIMMBF_02325 6.3e-134 IQ Enoyl-(Acyl carrier protein) reductase
HPBIMMBF_02326 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
HPBIMMBF_02327 1.1e-211 S Bacterial protein of unknown function (DUF871)
HPBIMMBF_02328 2e-230 S Sterol carrier protein domain
HPBIMMBF_02329 2.1e-225 EGP Major facilitator Superfamily
HPBIMMBF_02330 1e-87 niaR S 3H domain
HPBIMMBF_02331 3.6e-263 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPBIMMBF_02332 1.3e-117 K Transcriptional regulator
HPBIMMBF_02333 7e-154 V ABC transporter
HPBIMMBF_02334 2.4e-133 V AAA domain, putative AbiEii toxin, Type IV TA system
HPBIMMBF_02335 1.6e-241 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HPBIMMBF_02338 8.2e-23
HPBIMMBF_02339 1.8e-159 ypbG 2.7.1.2 GK ROK family
HPBIMMBF_02340 5.7e-264 lmrA 3.6.3.44 V ABC transporter
HPBIMMBF_02341 3.9e-51 lmrA 3.6.3.44 V ABC transporter
HPBIMMBF_02342 3.2e-95 rmaB K Transcriptional regulator, MarR family
HPBIMMBF_02343 1.3e-119 drgA C Nitroreductase family
HPBIMMBF_02344 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HPBIMMBF_02345 5.6e-110 cmpC S ATPases associated with a variety of cellular activities
HPBIMMBF_02346 3.8e-150 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HPBIMMBF_02347 3.5e-169 XK27_00670 S ABC transporter
HPBIMMBF_02348 2.2e-258
HPBIMMBF_02349 2.5e-62
HPBIMMBF_02350 2.8e-188 S Cell surface protein
HPBIMMBF_02351 2.3e-91 S WxL domain surface cell wall-binding
HPBIMMBF_02352 1.5e-96 acuB S Domain in cystathionine beta-synthase and other proteins.
HPBIMMBF_02353 8.9e-122 livF E ABC transporter
HPBIMMBF_02354 2.9e-137 livG E Branched-chain amino acid ATP-binding cassette transporter
HPBIMMBF_02355 4.5e-09 azoB GM NmrA-like family
HPBIMMBF_02356 1.6e-160 azoB GM NmrA-like family
HPBIMMBF_02357 2.1e-65 K Winged helix DNA-binding domain
HPBIMMBF_02358 7e-71 spx4 1.20.4.1 P ArsC family
HPBIMMBF_02359 4.1e-65 yeaO S Protein of unknown function, DUF488
HPBIMMBF_02360 4e-53
HPBIMMBF_02361 4.1e-214 mutY L A G-specific adenine glycosylase
HPBIMMBF_02362 1.9e-62
HPBIMMBF_02363 1.3e-85
HPBIMMBF_02364 4.5e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
HPBIMMBF_02365 2e-55
HPBIMMBF_02366 2.1e-14
HPBIMMBF_02367 9.6e-115 GM NmrA-like family
HPBIMMBF_02368 3.8e-81 elaA S GNAT family
HPBIMMBF_02369 1.6e-158 EG EamA-like transporter family
HPBIMMBF_02370 4.5e-118 S membrane
HPBIMMBF_02371 3.7e-109 S VIT family
HPBIMMBF_02372 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HPBIMMBF_02373 0.0 copB 3.6.3.4 P P-type ATPase
HPBIMMBF_02374 9.4e-74 copR K Copper transport repressor CopY TcrY
HPBIMMBF_02375 7.4e-40
HPBIMMBF_02376 1.3e-72 S COG NOG18757 non supervised orthologous group
HPBIMMBF_02377 4.2e-229 lmrB EGP Major facilitator Superfamily
HPBIMMBF_02378 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02379 8e-157 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HPBIMMBF_02380 4.8e-137 terC P membrane
HPBIMMBF_02381 5.3e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPBIMMBF_02382 3.7e-125 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPBIMMBF_02383 1e-63 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPBIMMBF_02384 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HPBIMMBF_02385 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPBIMMBF_02386 1.1e-119 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPBIMMBF_02387 7.7e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HPBIMMBF_02388 9.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPBIMMBF_02389 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HPBIMMBF_02390 3e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPBIMMBF_02391 6e-79 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HPBIMMBF_02392 4e-212 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HPBIMMBF_02393 3.2e-163 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
HPBIMMBF_02394 1e-215 ysaA V RDD family
HPBIMMBF_02395 7.6e-166 corA P CorA-like Mg2+ transporter protein
HPBIMMBF_02396 1e-49 S Domain of unknown function (DU1801)
HPBIMMBF_02397 1.3e-19 rmeB K transcriptional regulator, MerR family
HPBIMMBF_02398 2e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPBIMMBF_02399 1.5e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPBIMMBF_02400 3.3e-144 K Helix-turn-helix XRE-family like proteins
HPBIMMBF_02401 1.2e-264 yjeM E Amino Acid
HPBIMMBF_02402 2.3e-66 lysM M LysM domain
HPBIMMBF_02403 5.7e-222 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HPBIMMBF_02404 6e-213 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HPBIMMBF_02405 0.0 ctpA 3.6.3.54 P P-type ATPase
HPBIMMBF_02406 7e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPBIMMBF_02407 4.5e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPBIMMBF_02408 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPBIMMBF_02409 1.6e-132 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPBIMMBF_02410 8.7e-139 K Helix-turn-helix domain
HPBIMMBF_02411 4.6e-228 hpk9 2.7.13.3 T GHKL domain
HPBIMMBF_02412 3.3e-50 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HPBIMMBF_02413 6.2e-250 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HPBIMMBF_02414 7.2e-144 IQ NAD dependent epimerase/dehydratase family
HPBIMMBF_02415 2e-158 rbsU U ribose uptake protein RbsU
HPBIMMBF_02416 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HPBIMMBF_02417 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPBIMMBF_02418 3e-187 rbsR K helix_turn _helix lactose operon repressor
HPBIMMBF_02419 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPBIMMBF_02420 2.7e-79 T Universal stress protein family
HPBIMMBF_02421 2.2e-99 padR K Virulence activator alpha C-term
HPBIMMBF_02422 6e-102 padC Q Phenolic acid decarboxylase
HPBIMMBF_02423 1.3e-140 tesE Q hydratase
HPBIMMBF_02424 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
HPBIMMBF_02425 5.2e-156 degV S DegV family
HPBIMMBF_02426 2.9e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
HPBIMMBF_02427 1.7e-254 pepC 3.4.22.40 E aminopeptidase
HPBIMMBF_02428 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPBIMMBF_02429 5.6e-42
HPBIMMBF_02430 3.9e-56
HPBIMMBF_02431 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPBIMMBF_02432 1e-173 rihC 3.2.2.1 F Nucleoside
HPBIMMBF_02433 1.5e-161 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPBIMMBF_02434 0.0
HPBIMMBF_02435 4.2e-77 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
HPBIMMBF_02436 2.3e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPBIMMBF_02437 3.2e-178 proV E ABC transporter, ATP-binding protein
HPBIMMBF_02438 4.4e-255 gshR 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase
HPBIMMBF_02439 2.5e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPBIMMBF_02440 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HPBIMMBF_02441 7.3e-48 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPBIMMBF_02442 1.2e-73 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPBIMMBF_02443 3.1e-181 M domain protein
HPBIMMBF_02444 1e-57
HPBIMMBF_02445 1.1e-59 S Protein of unknown function (DUF1211)
HPBIMMBF_02446 1.7e-140 XK27_06930 S ABC-2 family transporter protein
HPBIMMBF_02447 1.3e-64 K Bacterial regulatory proteins, tetR family
HPBIMMBF_02449 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPBIMMBF_02450 5.1e-142 ptp2 3.1.3.48 T Tyrosine phosphatase family
HPBIMMBF_02451 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPBIMMBF_02452 8.9e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPBIMMBF_02453 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPBIMMBF_02454 1.7e-54 S Enterocin A Immunity
HPBIMMBF_02455 5.2e-256 gor 1.8.1.7 C Glutathione reductase
HPBIMMBF_02456 2.1e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPBIMMBF_02457 6e-182 D Alpha beta
HPBIMMBF_02458 1.7e-162 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
HPBIMMBF_02459 5.3e-131 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
HPBIMMBF_02460 2.1e-123 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
HPBIMMBF_02461 3.5e-118 yugP S Putative neutral zinc metallopeptidase
HPBIMMBF_02462 4.1e-25
HPBIMMBF_02463 2.7e-144 DegV S EDD domain protein, DegV family
HPBIMMBF_02464 7.3e-127 lrgB M LrgB-like family
HPBIMMBF_02465 5.6e-63 lrgA S LrgA family
HPBIMMBF_02466 1.1e-103 J Acetyltransferase (GNAT) domain
HPBIMMBF_02467 4.5e-168 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HPBIMMBF_02468 2e-35 S Phospholipase_D-nuclease N-terminal
HPBIMMBF_02469 4.6e-58 S Enterocin A Immunity
HPBIMMBF_02470 9.8e-88 perR P Belongs to the Fur family
HPBIMMBF_02471 6e-103
HPBIMMBF_02472 2.5e-236 S module of peptide synthetase
HPBIMMBF_02473 2e-100 S NADPH-dependent FMN reductase
HPBIMMBF_02474 5.4e-08
HPBIMMBF_02475 3.3e-126 magIII L Base excision DNA repair protein, HhH-GPD family
HPBIMMBF_02476 7.1e-284 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPBIMMBF_02477 3.5e-67 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPBIMMBF_02478 4.8e-36 1.6.5.2 GM NmrA-like family
HPBIMMBF_02479 1.8e-57 1.6.5.2 GM NmrA-like family
HPBIMMBF_02480 1.7e-31 1.6.5.2 GM NmrA-like family
HPBIMMBF_02481 6.6e-78 merR K MerR family regulatory protein
HPBIMMBF_02482 1.9e-147 cof S haloacid dehalogenase-like hydrolase
HPBIMMBF_02483 1.1e-147 qorB 1.6.5.2 GM NmrA-like family
HPBIMMBF_02484 9.4e-77
HPBIMMBF_02485 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPBIMMBF_02486 9.4e-118 ybbL S ABC transporter, ATP-binding protein
HPBIMMBF_02487 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
HPBIMMBF_02488 2.4e-203 S DUF218 domain
HPBIMMBF_02489 3.2e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HPBIMMBF_02490 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HPBIMMBF_02491 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPBIMMBF_02492 1.7e-128 S Putative adhesin
HPBIMMBF_02493 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
HPBIMMBF_02494 1.5e-52 K Transcriptional regulator
HPBIMMBF_02495 1.4e-77 KT response to antibiotic
HPBIMMBF_02496 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HPBIMMBF_02497 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPBIMMBF_02498 8.1e-123 tcyB E ABC transporter
HPBIMMBF_02499 5.2e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HPBIMMBF_02500 2.3e-234 EK Aminotransferase, class I
HPBIMMBF_02501 6.1e-168 K LysR substrate binding domain
HPBIMMBF_02502 4.4e-144 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_02503 3.8e-161 S Bacterial membrane protein, YfhO
HPBIMMBF_02504 1.6e-225 nupG F Nucleoside
HPBIMMBF_02505 2.1e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HPBIMMBF_02506 2.7e-149 noc K Belongs to the ParB family
HPBIMMBF_02507 1.8e-136 soj D Sporulation initiation inhibitor
HPBIMMBF_02508 2.4e-156 spo0J K Belongs to the ParB family
HPBIMMBF_02509 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
HPBIMMBF_02510 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPBIMMBF_02511 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
HPBIMMBF_02512 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPBIMMBF_02513 3.3e-139 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPBIMMBF_02514 1e-122 yoaK S Protein of unknown function (DUF1275)
HPBIMMBF_02515 3.2e-124 K response regulator
HPBIMMBF_02516 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
HPBIMMBF_02517 4.2e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPBIMMBF_02518 4.9e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HPBIMMBF_02519 5.1e-131 azlC E branched-chain amino acid
HPBIMMBF_02520 2.3e-54 azlD S branched-chain amino acid
HPBIMMBF_02521 1.8e-109 S membrane transporter protein
HPBIMMBF_02522 4.1e-54
HPBIMMBF_02523 1.5e-74 S Psort location Cytoplasmic, score
HPBIMMBF_02524 3.9e-96 S Domain of unknown function (DUF4352)
HPBIMMBF_02525 1.9e-200 KLT Protein tyrosine kinase
HPBIMMBF_02526 3.4e-158
HPBIMMBF_02527 6.8e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HPBIMMBF_02528 2.3e-78
HPBIMMBF_02530 1.7e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPBIMMBF_02531 1.3e-162 FbpA K Domain of unknown function (DUF814)
HPBIMMBF_02532 1.7e-60 S Domain of unknown function (DU1801)
HPBIMMBF_02533 2.1e-32
HPBIMMBF_02534 3.8e-179 yghZ C Aldo keto reductase family protein
HPBIMMBF_02535 6.7e-113 pgm1 G phosphoglycerate mutase
HPBIMMBF_02536 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPBIMMBF_02537 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPBIMMBF_02538 3.8e-78 yiaC K Acetyltransferase (GNAT) domain
HPBIMMBF_02539 3.5e-310 oppA E ABC transporter, substratebinding protein
HPBIMMBF_02540 0.0 oppA E ABC transporter, substratebinding protein
HPBIMMBF_02541 2.1e-157 hipB K Helix-turn-helix
HPBIMMBF_02543 0.0 3.6.4.13 M domain protein
HPBIMMBF_02544 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HPBIMMBF_02545 1.3e-153 tagG U Transport permease protein
HPBIMMBF_02546 1.4e-217
HPBIMMBF_02547 1.1e-223 mtnE 2.6.1.83 E Aminotransferase
HPBIMMBF_02548 2.6e-60 S CHY zinc finger
HPBIMMBF_02549 1.6e-169 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPBIMMBF_02550 6.8e-96 bioY S BioY family
HPBIMMBF_02551 3e-40
HPBIMMBF_02552 5e-153 pipD E Dipeptidase
HPBIMMBF_02553 2.4e-116 pipD E Dipeptidase
HPBIMMBF_02554 3e-30
HPBIMMBF_02555 6.7e-122 qmcA O prohibitin homologues
HPBIMMBF_02556 2.3e-240 xylP1 G MFS/sugar transport protein
HPBIMMBF_02558 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HPBIMMBF_02559 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HPBIMMBF_02560 2.9e-140
HPBIMMBF_02561 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02562 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPBIMMBF_02563 2e-115 3.6.1.27 I Acid phosphatase homologues
HPBIMMBF_02564 5e-93 ytqB 2.1.1.176 J Putative rRNA methylase
HPBIMMBF_02565 4.2e-29
HPBIMMBF_02566 9.1e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HPBIMMBF_02567 1.6e-244 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HPBIMMBF_02568 1.4e-303 S Pfam Methyltransferase
HPBIMMBF_02569 4.4e-139 N Cell shape-determining protein MreB
HPBIMMBF_02571 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02572 1.4e-278 bmr3 EGP Major facilitator Superfamily
HPBIMMBF_02573 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPBIMMBF_02574 3.1e-122
HPBIMMBF_02575 9.7e-152 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HPBIMMBF_02576 1.3e-114 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HPBIMMBF_02577 5.4e-167 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HPBIMMBF_02578 1.2e-255 mmuP E amino acid
HPBIMMBF_02579 1.5e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HPBIMMBF_02580 5.2e-232 mntH P H( )-stimulated, divalent metal cation uptake system
HPBIMMBF_02582 2.9e-156 T Calcineurin-like phosphoesterase superfamily domain
HPBIMMBF_02583 2e-94 K Acetyltransferase (GNAT) domain
HPBIMMBF_02584 4.5e-94
HPBIMMBF_02585 6.4e-180 P secondary active sulfate transmembrane transporter activity
HPBIMMBF_02586 7.7e-89 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HPBIMMBF_02589 1.5e-90 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPBIMMBF_02590 1.4e-300 uvrA2 L ABC transporter
HPBIMMBF_02591 6.8e-24 L Integrase
HPBIMMBF_02592 1.2e-26 L Integrase
HPBIMMBF_02593 1.6e-29 S Enterocin A Immunity
HPBIMMBF_02594 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HPBIMMBF_02595 8.3e-168 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02596 2.9e-140 cylB V ABC-2 type transporter
HPBIMMBF_02597 1.4e-153 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HPBIMMBF_02598 2.9e-102 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HPBIMMBF_02599 5.9e-57 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HPBIMMBF_02600 3.1e-56 tnp2PF3 L Transposase DDE domain
HPBIMMBF_02601 1.3e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HPBIMMBF_02603 5.2e-167 G Belongs to the carbohydrate kinase PfkB family
HPBIMMBF_02604 2.1e-252 F Belongs to the purine-cytosine permease (2.A.39) family
HPBIMMBF_02605 1.9e-194 yegU O ADP-ribosylglycohydrolase
HPBIMMBF_02606 4.7e-79 uspA T universal stress protein
HPBIMMBF_02607 3.3e-153 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPBIMMBF_02608 2.3e-48 K Cro/C1-type HTH DNA-binding domain
HPBIMMBF_02609 3e-223 lsgC M Glycosyl transferases group 1
HPBIMMBF_02610 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HPBIMMBF_02611 1.2e-165 S Putative esterase
HPBIMMBF_02612 2.4e-130 gntR2 K Transcriptional regulator
HPBIMMBF_02613 1.4e-89 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPBIMMBF_02614 5.2e-139
HPBIMMBF_02615 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPBIMMBF_02616 5.5e-138 rrp8 K LytTr DNA-binding domain
HPBIMMBF_02617 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
HPBIMMBF_02618 7.7e-61
HPBIMMBF_02619 4.6e-73 hspX O Belongs to the small heat shock protein (HSP20) family
HPBIMMBF_02620 5.8e-58
HPBIMMBF_02621 3.5e-239 yhdP S Transporter associated domain
HPBIMMBF_02622 7.4e-63 L Integrase core domain
HPBIMMBF_02623 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HPBIMMBF_02624 4.1e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPBIMMBF_02625 1.7e-155 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
HPBIMMBF_02626 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPBIMMBF_02627 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HPBIMMBF_02628 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HPBIMMBF_02629 7.8e-274 cydA 1.10.3.14 C ubiquinol oxidase
HPBIMMBF_02630 5.5e-16 S Alpha beta
HPBIMMBF_02631 3.6e-303 S Alpha beta
HPBIMMBF_02632 1.8e-23
HPBIMMBF_02633 3e-99 S ECF transporter, substrate-specific component
HPBIMMBF_02634 7.5e-253 yfnA E Amino Acid
HPBIMMBF_02636 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HPBIMMBF_02637 3e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
HPBIMMBF_02638 7.8e-12
HPBIMMBF_02639 1e-154 L Integrase core domain
HPBIMMBF_02641 2.9e-88 L PFAM Integrase catalytic region
HPBIMMBF_02642 3.5e-53 L Helix-turn-helix domain
HPBIMMBF_02643 9.7e-101 N Uncharacterized conserved protein (DUF2075)
HPBIMMBF_02644 0.0 pepN 3.4.11.2 E aminopeptidase
HPBIMMBF_02645 1.6e-187 S PglZ domain
HPBIMMBF_02646 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02647 1e-252 S response to antibiotic
HPBIMMBF_02648 7e-133 S zinc-ribbon domain
HPBIMMBF_02650 3.2e-37
HPBIMMBF_02651 6.3e-134 aroD S Alpha/beta hydrolase family
HPBIMMBF_02652 7e-174 S Phosphotransferase system, EIIC
HPBIMMBF_02653 1.1e-267 I acetylesterase activity
HPBIMMBF_02654 5.5e-174 sdrF M Collagen binding domain
HPBIMMBF_02655 2.4e-33 sdrF M Collagen binding domain
HPBIMMBF_02656 1.8e-159 yicL EG EamA-like transporter family
HPBIMMBF_02657 4.4e-129 E lipolytic protein G-D-S-L family
HPBIMMBF_02658 1.1e-177 4.1.1.52 S Amidohydrolase
HPBIMMBF_02659 1.8e-110 K Transcriptional regulator C-terminal region
HPBIMMBF_02660 1.8e-47 3.6.4.12 K HxlR-like helix-turn-helix
HPBIMMBF_02661 6.8e-52 V COG1131 ABC-type multidrug transport system, ATPase component
HPBIMMBF_02663 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPBIMMBF_02664 1.9e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPBIMMBF_02665 7.8e-41 rpmE2 J Ribosomal protein L31
HPBIMMBF_02666 3.9e-212 J translation release factor activity
HPBIMMBF_02667 7.8e-126 srtA 3.4.22.70 M sortase family
HPBIMMBF_02668 1.7e-91 lemA S LemA family
HPBIMMBF_02669 3.5e-139 htpX O Belongs to the peptidase M48B family
HPBIMMBF_02670 3.6e-73
HPBIMMBF_02671 8.9e-56
HPBIMMBF_02672 2.8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPBIMMBF_02673 1.5e-257 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPBIMMBF_02674 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPBIMMBF_02675 1.4e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPBIMMBF_02676 1.7e-128
HPBIMMBF_02677 0.0 typA T GTP-binding protein TypA
HPBIMMBF_02678 2e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HPBIMMBF_02679 4.7e-45 yktA S Belongs to the UPF0223 family
HPBIMMBF_02680 4.2e-163 1.1.1.27 C L-malate dehydrogenase activity
HPBIMMBF_02681 1.7e-265 lpdA 1.8.1.4 C Dehydrogenase
HPBIMMBF_02682 2.3e-200 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HPBIMMBF_02683 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HPBIMMBF_02684 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HPBIMMBF_02685 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPBIMMBF_02686 8.2e-85
HPBIMMBF_02687 3.1e-33 ykzG S Belongs to the UPF0356 family
HPBIMMBF_02688 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPBIMMBF_02689 1.3e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HPBIMMBF_02690 1.7e-28
HPBIMMBF_02691 5.5e-105 mltD CBM50 M NlpC P60 family protein
HPBIMMBF_02692 2.9e-171 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPBIMMBF_02693 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPBIMMBF_02694 1.6e-120 S Repeat protein
HPBIMMBF_02695 1.6e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HPBIMMBF_02696 3.8e-268 N domain, Protein
HPBIMMBF_02697 2.2e-193 S Bacterial protein of unknown function (DUF916)
HPBIMMBF_02698 1.5e-108 N WxL domain surface cell wall-binding
HPBIMMBF_02699 2.6e-115 ktrA P domain protein
HPBIMMBF_02700 1.1e-240 ktrB P Potassium uptake protein
HPBIMMBF_02701 9.1e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPBIMMBF_02702 4.9e-57 XK27_04120 S Putative amino acid metabolism
HPBIMMBF_02703 4.7e-216 iscS 2.8.1.7 E Aminotransferase class V
HPBIMMBF_02704 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPBIMMBF_02705 9.2e-29
HPBIMMBF_02706 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HPBIMMBF_02707 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPBIMMBF_02708 9e-18 S Protein of unknown function (DUF3021)
HPBIMMBF_02709 1.3e-36 K LytTr DNA-binding domain
HPBIMMBF_02710 3.6e-80 cylB U ABC-2 type transporter
HPBIMMBF_02711 8.8e-79 cylA V abc transporter atp-binding protein
HPBIMMBF_02712 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPBIMMBF_02713 1.2e-86 divIVA D DivIVA domain protein
HPBIMMBF_02714 2.2e-145 ylmH S S4 domain protein
HPBIMMBF_02715 1.2e-36 yggT S YGGT family
HPBIMMBF_02716 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPBIMMBF_02717 3.1e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPBIMMBF_02718 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPBIMMBF_02719 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPBIMMBF_02720 3.4e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPBIMMBF_02721 4.7e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPBIMMBF_02722 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPBIMMBF_02723 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HPBIMMBF_02724 7.5e-54 ftsL D Cell division protein FtsL
HPBIMMBF_02725 9.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPBIMMBF_02726 4.2e-77 mraZ K Belongs to the MraZ family
HPBIMMBF_02727 5.4e-62 S Protein of unknown function (DUF3397)
HPBIMMBF_02728 1.2e-174 corA P CorA-like Mg2+ transporter protein
HPBIMMBF_02729 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HPBIMMBF_02730 6.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPBIMMBF_02731 2.9e-111 ywnB S NAD(P)H-binding
HPBIMMBF_02732 5.9e-231 brnQ U Component of the transport system for branched-chain amino acids
HPBIMMBF_02734 2e-160 rrmA 2.1.1.187 H Methyltransferase
HPBIMMBF_02735 3.9e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPBIMMBF_02736 6.2e-205 XK27_05220 S AI-2E family transporter
HPBIMMBF_02737 5.7e-56 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HPBIMMBF_02738 2.4e-192 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HPBIMMBF_02739 1.4e-113 cutC P Participates in the control of copper homeostasis
HPBIMMBF_02740 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HPBIMMBF_02741 1.8e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPBIMMBF_02742 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
HPBIMMBF_02743 1.8e-113 yjbH Q Thioredoxin
HPBIMMBF_02744 0.0 pepF E oligoendopeptidase F
HPBIMMBF_02745 1.9e-83 coiA 3.6.4.12 S Competence protein
HPBIMMBF_02746 2.3e-107 coiA 3.6.4.12 S Competence protein
HPBIMMBF_02747 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPBIMMBF_02748 1.3e-16 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPBIMMBF_02749 1e-257 yhdG E C-terminus of AA_permease
HPBIMMBF_02751 0.0 kup P Transport of potassium into the cell
HPBIMMBF_02752 6.7e-165 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPBIMMBF_02753 3.1e-179 K AI-2E family transporter
HPBIMMBF_02754 7.6e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HPBIMMBF_02755 1.3e-58 qacC P Small Multidrug Resistance protein
HPBIMMBF_02756 1.1e-44 qacH U Small Multidrug Resistance protein
HPBIMMBF_02757 3e-116 hly S protein, hemolysin III
HPBIMMBF_02758 8.7e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HPBIMMBF_02759 1.8e-159 czcD P cation diffusion facilitator family transporter
HPBIMMBF_02760 1.5e-101 K Helix-turn-helix XRE-family like proteins
HPBIMMBF_02762 1.1e-17
HPBIMMBF_02763 1.5e-103 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPBIMMBF_02764 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HPBIMMBF_02765 4.3e-80
HPBIMMBF_02766 1.7e-72 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPBIMMBF_02767 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPBIMMBF_02768 1.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPBIMMBF_02769 4.9e-22
HPBIMMBF_02770 3.2e-69
HPBIMMBF_02771 8.4e-165 K LysR substrate binding domain
HPBIMMBF_02772 4e-243 P Sodium:sulfate symporter transmembrane region
HPBIMMBF_02773 1.5e-94 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HPBIMMBF_02774 6.1e-182 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HPBIMMBF_02775 5.1e-27
HPBIMMBF_02776 1.4e-130 S YheO-like PAS domain
HPBIMMBF_02777 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HPBIMMBF_02778 8.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HPBIMMBF_02779 3.1e-229 tdcC E amino acid
HPBIMMBF_02780 2.3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPBIMMBF_02781 3.8e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPBIMMBF_02782 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPBIMMBF_02783 3.8e-78 ywiB S Domain of unknown function (DUF1934)
HPBIMMBF_02784 4.5e-166 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HPBIMMBF_02785 9e-264 ywfO S HD domain protein
HPBIMMBF_02786 1.7e-148 yxeH S hydrolase
HPBIMMBF_02787 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HPBIMMBF_02788 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HPBIMMBF_02789 4.7e-163 fabK 1.3.1.9 S Nitronate monooxygenase
HPBIMMBF_02790 0.0 helD 3.6.4.12 L DNA helicase
HPBIMMBF_02791 6.5e-111 dedA S SNARE associated Golgi protein
HPBIMMBF_02792 1.3e-176 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
HPBIMMBF_02793 0.0 yjbQ P TrkA C-terminal domain protein
HPBIMMBF_02794 4.7e-125 pgm3 G Phosphoglycerate mutase family
HPBIMMBF_02795 6.1e-128 pgm3 G Phosphoglycerate mutase family
HPBIMMBF_02796 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02797 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02798 1.4e-63 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPBIMMBF_02800 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HPBIMMBF_02801 9.1e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HPBIMMBF_02802 1.8e-12
HPBIMMBF_02803 8.7e-160 2.7.13.3 T GHKL domain
HPBIMMBF_02804 2.2e-134 K LytTr DNA-binding domain
HPBIMMBF_02805 4.9e-78 yneH 1.20.4.1 K ArsC family
HPBIMMBF_02806 2.1e-290 katA 1.11.1.6 C Belongs to the catalase family
HPBIMMBF_02807 9e-13 ytgB S Transglycosylase associated protein
HPBIMMBF_02808 3e-10
HPBIMMBF_02809 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HPBIMMBF_02810 4.2e-70 S Pyrimidine dimer DNA glycosylase
HPBIMMBF_02811 9.2e-86 L COG2801 Transposase and inactivated derivatives
HPBIMMBF_02812 5e-162 degV S Uncharacterised protein, DegV family COG1307
HPBIMMBF_02813 1.5e-86 hom1 1.1.1.3 E Homoserine dehydrogenase
HPBIMMBF_02814 1.6e-129 hom1 1.1.1.3 E Homoserine dehydrogenase
HPBIMMBF_02815 2.2e-243 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HPBIMMBF_02816 1.1e-164 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HPBIMMBF_02817 5.3e-176 XK27_08835 S ABC transporter
HPBIMMBF_02818 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HPBIMMBF_02819 1.2e-135 XK27_08845 S ABC transporter, ATP-binding protein
HPBIMMBF_02820 2.5e-258 npr 1.11.1.1 C NADH oxidase
HPBIMMBF_02821 6.7e-41 yliE T EAL domain
HPBIMMBF_02822 2.1e-75 yliE T EAL domain
HPBIMMBF_02823 1.4e-217 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HPBIMMBF_02824 1.4e-87 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPBIMMBF_02825 1.2e-38 S Cytochrome B5
HPBIMMBF_02826 2.5e-235
HPBIMMBF_02827 5e-128 treR K UTRA
HPBIMMBF_02828 1e-15 I alpha/beta hydrolase fold
HPBIMMBF_02829 1.9e-118 I alpha/beta hydrolase fold
HPBIMMBF_02830 5.1e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
HPBIMMBF_02831 2.9e-232 yxiO S Vacuole effluxer Atg22 like
HPBIMMBF_02832 8.5e-79 K LysR substrate binding domain
HPBIMMBF_02833 7.8e-103 GM NAD(P)H-binding
HPBIMMBF_02834 1.6e-191 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HPBIMMBF_02835 5.5e-150 IQ Enoyl-(Acyl carrier protein) reductase
HPBIMMBF_02836 1.3e-34
HPBIMMBF_02837 3e-75 T Belongs to the universal stress protein A family
HPBIMMBF_02838 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HPBIMMBF_02839 3.2e-124 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPBIMMBF_02840 4e-95
HPBIMMBF_02841 9.7e-61 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPBIMMBF_02842 2.6e-35
HPBIMMBF_02843 3.9e-77
HPBIMMBF_02844 3.7e-20 ybfG M peptidoglycan-binding domain-containing protein
HPBIMMBF_02845 4.7e-153 ybfG M Domain of unknown function (DUF1906)
HPBIMMBF_02846 3.6e-102 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
HPBIMMBF_02847 7.9e-45 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HPBIMMBF_02848 7.9e-41
HPBIMMBF_02849 1.9e-67 tspO T TspO/MBR family
HPBIMMBF_02850 6.3e-76 uspA T Belongs to the universal stress protein A family
HPBIMMBF_02851 2.3e-65 S Protein of unknown function (DUF805)
HPBIMMBF_02852 3.5e-163 yegS I Diacylglycerol kinase catalytic domain
HPBIMMBF_02853 6.5e-35
HPBIMMBF_02854 3.1e-14
HPBIMMBF_02855 6.5e-41 S transglycosylase associated protein
HPBIMMBF_02856 4.8e-29 S CsbD-like
HPBIMMBF_02857 9.4e-40
HPBIMMBF_02858 2.6e-277 pipD E Dipeptidase
HPBIMMBF_02859 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HPBIMMBF_02860 1.1e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPBIMMBF_02861 3.9e-170 2.5.1.74 H UbiA prenyltransferase family
HPBIMMBF_02862 5.2e-167 ywhK S Membrane
HPBIMMBF_02863 3.4e-163 degV S Uncharacterised protein, DegV family COG1307
HPBIMMBF_02864 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HPBIMMBF_02865 3.8e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPBIMMBF_02866 9.2e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPBIMMBF_02867 4.7e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPBIMMBF_02868 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPBIMMBF_02869 8.9e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPBIMMBF_02870 1.2e-224 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPBIMMBF_02871 3.5e-142 cad S FMN_bind
HPBIMMBF_02872 2.3e-63 K helix_turn_helix, mercury resistance
HPBIMMBF_02873 2.5e-172 C Zinc-binding dehydrogenase
HPBIMMBF_02874 8.5e-57 S SdpI/YhfL protein family
HPBIMMBF_02875 1.1e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPBIMMBF_02876 6.7e-259 gabR K Bacterial regulatory proteins, gntR family
HPBIMMBF_02877 5e-218 patA 2.6.1.1 E Aminotransferase
HPBIMMBF_02878 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPBIMMBF_02879 3e-18
HPBIMMBF_02880 1.7e-126 S membrane transporter protein
HPBIMMBF_02881 1e-159 mleR K LysR family
HPBIMMBF_02882 5.6e-115 ylbE GM NAD(P)H-binding
HPBIMMBF_02883 6.5e-93 wecD K Acetyltransferase (GNAT) family
HPBIMMBF_02884 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HPBIMMBF_02885 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HPBIMMBF_02886 5e-168 ydcZ S Putative inner membrane exporter, YdcZ
HPBIMMBF_02887 1.2e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPBIMMBF_02888 1.5e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPBIMMBF_02889 7.7e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPBIMMBF_02890 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPBIMMBF_02891 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPBIMMBF_02892 1.7e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPBIMMBF_02893 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HPBIMMBF_02894 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPBIMMBF_02895 1.3e-298 pucR QT Purine catabolism regulatory protein-like family
HPBIMMBF_02896 2.7e-236 pbuX F xanthine permease
HPBIMMBF_02897 2.4e-221 pbuG S Permease family
HPBIMMBF_02898 2.8e-160 GM NmrA-like family
HPBIMMBF_02899 1.6e-154 T EAL domain
HPBIMMBF_02900 8.4e-77
HPBIMMBF_02901 6.2e-143 pgaC GT2 M Glycosyl transferase
HPBIMMBF_02902 7.4e-74 pgaC GT2 M Glycosyl transferase
HPBIMMBF_02903 6.9e-124 2.1.1.14 E Methionine synthase
HPBIMMBF_02904 2.3e-213 purD 6.3.4.13 F Belongs to the GARS family
HPBIMMBF_02905 1.1e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HPBIMMBF_02906 4.9e-102 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPBIMMBF_02907 9.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HPBIMMBF_02908 7.4e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPBIMMBF_02909 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPBIMMBF_02910 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPBIMMBF_02911 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPBIMMBF_02912 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HPBIMMBF_02913 2.2e-210 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPBIMMBF_02914 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPBIMMBF_02915 4.8e-222 XK27_09615 1.3.5.4 S reductase
HPBIMMBF_02916 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
HPBIMMBF_02917 6.4e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HPBIMMBF_02918 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HPBIMMBF_02919 4.6e-117 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HPBIMMBF_02920 3.7e-148 S Alpha/beta hydrolase of unknown function (DUF915)
HPBIMMBF_02921 4.9e-179 ansA 3.5.1.1 EJ Asparaginase
HPBIMMBF_02922 5.6e-138 cysA V ABC transporter, ATP-binding protein
HPBIMMBF_02923 0.0 V FtsX-like permease family
HPBIMMBF_02924 5.2e-41
HPBIMMBF_02925 7.9e-61 gntR1 K Transcriptional regulator, GntR family
HPBIMMBF_02926 6.9e-164 V ABC transporter, ATP-binding protein
HPBIMMBF_02927 2.9e-148
HPBIMMBF_02928 6.7e-81 uspA T universal stress protein
HPBIMMBF_02929 4.2e-71 gtcA S Teichoic acid glycosylation protein
HPBIMMBF_02930 1.1e-88
HPBIMMBF_02931 1.9e-50
HPBIMMBF_02933 7.5e-230 malY 4.4.1.8 E Aminotransferase, class I
HPBIMMBF_02934 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
HPBIMMBF_02935 5.4e-118
HPBIMMBF_02936 1.5e-52
HPBIMMBF_02938 5e-172 repA S Replication initiator protein A
HPBIMMBF_02939 2.9e-35
HPBIMMBF_02940 4e-150 D CobQ CobB MinD ParA nucleotide binding domain protein
HPBIMMBF_02941 2.5e-20
HPBIMMBF_02942 8.5e-32
HPBIMMBF_02943 1.4e-73 K Bacterial regulatory proteins, tetR family
HPBIMMBF_02944 6.9e-52 L DNA synthesis involved in DNA repair
HPBIMMBF_02945 3.4e-36 1.20.4.1 P ArsC family
HPBIMMBF_02947 1.4e-81 tnpR1 L Resolvase, N terminal domain
HPBIMMBF_02948 1.7e-210 xylR GK ROK family
HPBIMMBF_02949 1.3e-169 K AI-2E family transporter
HPBIMMBF_02950 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPBIMMBF_02951 1e-112 Q Methyltransferase domain
HPBIMMBF_02952 6.4e-35
HPBIMMBF_02953 3.3e-39 GM NAD(P)H-binding
HPBIMMBF_02954 3.5e-171 2.7.1.194, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPBIMMBF_02955 5.5e-43 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPBIMMBF_02956 3.9e-26 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HPBIMMBF_02957 5.9e-29 G PTS system sugar-specific permease component
HPBIMMBF_02958 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_02959 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HPBIMMBF_02960 2e-230 flhF N Uncharacterized conserved protein (DUF2075)
HPBIMMBF_02961 7.4e-94 yxkA S Phosphatidylethanolamine-binding protein
HPBIMMBF_02962 1.1e-54 ypaA S Protein of unknown function (DUF1304)
HPBIMMBF_02963 1.5e-310 mco Q Multicopper oxidase
HPBIMMBF_02964 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HPBIMMBF_02965 9.1e-101 zmp1 O Zinc-dependent metalloprotease
HPBIMMBF_02966 3.7e-44
HPBIMMBF_02967 3.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HPBIMMBF_02968 9.4e-242 amtB P ammonium transporter
HPBIMMBF_02969 7e-40
HPBIMMBF_02971 3.1e-67 EGP Major facilitator Superfamily
HPBIMMBF_02972 1.6e-118 EGP Major facilitator Superfamily
HPBIMMBF_02973 7.5e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HPBIMMBF_02974 4e-82 cvpA S Colicin V production protein
HPBIMMBF_02975 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPBIMMBF_02976 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HPBIMMBF_02977 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HPBIMMBF_02978 4.8e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPBIMMBF_02979 5.6e-98 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HPBIMMBF_02980 2.6e-211 folP 2.5.1.15 H dihydropteroate synthase
HPBIMMBF_02981 6.5e-96 tag 3.2.2.20 L glycosylase
HPBIMMBF_02984 4.2e-62
HPBIMMBF_02985 2.5e-53
HPBIMMBF_02986 6e-72 mltD CBM50 M PFAM NLP P60 protein
HPBIMMBF_02987 6.3e-284 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HPBIMMBF_02988 1.8e-27
HPBIMMBF_02989 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HPBIMMBF_02990 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
HPBIMMBF_02991 3.5e-88 K Winged helix DNA-binding domain
HPBIMMBF_02992 1.6e-115 S Protein of unknown function (DUF554)
HPBIMMBF_02993 4e-92 yueI S Protein of unknown function (DUF1694)
HPBIMMBF_02994 5.9e-143 yvpB S Peptidase_C39 like family
HPBIMMBF_02996 2.2e-150 M Glycosyl hydrolases family 25
HPBIMMBF_02997 5.1e-111
HPBIMMBF_02998 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPBIMMBF_02999 9e-84 hmpT S Pfam:DUF3816
HPBIMMBF_03000 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HPBIMMBF_03001 5.5e-189 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HPBIMMBF_03002 3e-196 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPBIMMBF_03003 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPBIMMBF_03004 1.5e-92 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HPBIMMBF_03005 6.4e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
HPBIMMBF_03006 9e-240 gshR1 1.8.1.7 C Glutathione reductase
HPBIMMBF_03007 5.2e-25
HPBIMMBF_03008 2.9e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HPBIMMBF_03009 6.9e-220 pbpX1 V Beta-lactamase
HPBIMMBF_03010 9.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HPBIMMBF_03011 1.1e-156 yihY S Belongs to the UPF0761 family
HPBIMMBF_03012 3.7e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPBIMMBF_03013 2e-94 L Transposase
HPBIMMBF_03014 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_03016 4.3e-262 L helicase superfamily c-terminal domain
HPBIMMBF_03017 5.9e-291 V Type II restriction enzyme, methylase subunits
HPBIMMBF_03018 6.5e-50 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_03019 1.3e-194 L Psort location Cytoplasmic, score
HPBIMMBF_03020 2.4e-33
HPBIMMBF_03021 1.2e-269 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HPBIMMBF_03022 0.0 traA L MobA MobL family protein
HPBIMMBF_03023 2.4e-22
HPBIMMBF_03024 8.9e-41
HPBIMMBF_03025 3.2e-51 Q Methyltransferase
HPBIMMBF_03026 8.8e-20
HPBIMMBF_03027 7.5e-78 K Peptidase S24-like
HPBIMMBF_03028 4.8e-57 dinG 2.7.7.7, 3.6.4.12 L DNA-directed DNA polymerase activity
HPBIMMBF_03034 1.6e-58 L Belongs to the 'phage' integrase family
HPBIMMBF_03035 1.6e-31
HPBIMMBF_03036 5.8e-143 Q Methyltransferase
HPBIMMBF_03037 3.2e-56 ybjQ S Belongs to the UPF0145 family
HPBIMMBF_03038 2.2e-208 EGP Major facilitator Superfamily
HPBIMMBF_03039 3.3e-98 K Helix-turn-helix domain
HPBIMMBF_03040 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPBIMMBF_03041 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HPBIMMBF_03042 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
HPBIMMBF_03043 2.4e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPBIMMBF_03044 1.1e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPBIMMBF_03045 3.2e-46
HPBIMMBF_03046 4.5e-244 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPBIMMBF_03047 2.6e-135 fruR K DeoR C terminal sensor domain
HPBIMMBF_03048 4.6e-171 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HPBIMMBF_03049 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HPBIMMBF_03050 1.4e-248 cpdA S Calcineurin-like phosphoesterase
HPBIMMBF_03051 1.3e-260 cps4J S Polysaccharide biosynthesis protein
HPBIMMBF_03052 1.6e-157 cps4I M Glycosyltransferase like family 2
HPBIMMBF_03053 5.2e-229
HPBIMMBF_03054 2.9e-182 cps4G M Glycosyltransferase Family 4
HPBIMMBF_03055 9.7e-200 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
HPBIMMBF_03056 6e-128 tuaA M Bacterial sugar transferase
HPBIMMBF_03057 6.3e-148 cps4D 5.1.3.2 M RmlD substrate binding domain
HPBIMMBF_03058 2.2e-54 ywqE 3.1.3.48 GM PHP domain protein
HPBIMMBF_03059 1.2e-80 ywqE 3.1.3.48 GM PHP domain protein
HPBIMMBF_03060 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HPBIMMBF_03061 4.9e-25 epsB M biosynthesis protein
HPBIMMBF_03062 1.1e-82 epsB M biosynthesis protein
HPBIMMBF_03063 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPBIMMBF_03064 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPBIMMBF_03065 9.2e-270 glnPH2 P ABC transporter permease
HPBIMMBF_03066 4.3e-22
HPBIMMBF_03067 9.9e-73 S Iron-sulphur cluster biosynthesis
HPBIMMBF_03068 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HPBIMMBF_03069 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HPBIMMBF_03070 9.7e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPBIMMBF_03071 5.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPBIMMBF_03072 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPBIMMBF_03073 2.5e-156 S Tetratricopeptide repeat
HPBIMMBF_03074 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPBIMMBF_03075 4.4e-155 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPBIMMBF_03076 9.1e-47 mdtG EGP Major Facilitator Superfamily
HPBIMMBF_03077 2.2e-79 mdtG EGP Major Facilitator Superfamily
HPBIMMBF_03078 5.4e-16 mdtG EGP Major Facilitator Superfamily
HPBIMMBF_03079 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPBIMMBF_03080 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HPBIMMBF_03081 5.9e-186 holA 2.7.7.7 L DNA polymerase III delta subunit
HPBIMMBF_03082 3.7e-229 comEC S Competence protein ComEC
HPBIMMBF_03083 7.6e-169 comEC S Competence protein ComEC
HPBIMMBF_03084 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
HPBIMMBF_03085 2.2e-120 comEA L Competence protein ComEA
HPBIMMBF_03086 3.6e-196 ylbL T Belongs to the peptidase S16 family
HPBIMMBF_03087 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPBIMMBF_03088 6.9e-101 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HPBIMMBF_03089 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HPBIMMBF_03090 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HPBIMMBF_03091 2.8e-205 ftsW D Belongs to the SEDS family
HPBIMMBF_03092 1.1e-41
HPBIMMBF_03093 5.7e-87
HPBIMMBF_03094 9.6e-258 ica2 GT2 M Glycosyl transferase family group 2
HPBIMMBF_03095 1.2e-103
HPBIMMBF_03096 9.2e-59
HPBIMMBF_03097 1.5e-64 M LysM domain
HPBIMMBF_03098 5.1e-75 K helix_turn_helix, mercury resistance
HPBIMMBF_03099 2.4e-184 1.1.1.219 GM Male sterility protein
HPBIMMBF_03100 2e-279 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPBIMMBF_03101 1e-268 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPBIMMBF_03102 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPBIMMBF_03103 3.4e-56 L Transposase IS66 family
HPBIMMBF_03104 1.5e-194 pbuX F xanthine permease
HPBIMMBF_03105 2.4e-192 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_03106 2.5e-54 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPBIMMBF_03107 0.0 cadA 3.6.3.3, 3.6.3.5 P Cadmium transporter
HPBIMMBF_03108 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_03109 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_03110 2.7e-16
HPBIMMBF_03111 1.7e-261 M MucBP domain
HPBIMMBF_03112 0.0 bztC D nuclear chromosome segregation
HPBIMMBF_03113 7.3e-83 K MarR family
HPBIMMBF_03114 1.4e-43
HPBIMMBF_03115 2e-38
HPBIMMBF_03116 8.3e-182 L PFAM Integrase, catalytic core
HPBIMMBF_03117 3.1e-99 tnp L DDE domain
HPBIMMBF_03118 4.5e-18 uspA T Belongs to the universal stress protein A family
HPBIMMBF_03119 8.8e-20 L Transposase
HPBIMMBF_03120 1.6e-102 gbuC E glycine betaine
HPBIMMBF_03121 1.8e-97 proW E glycine betaine
HPBIMMBF_03122 1.1e-153 gbuA 3.6.1.1, 3.6.3.32 E glycine betaine
HPBIMMBF_03123 3.7e-301 ybeC E amino acid
HPBIMMBF_03124 5.7e-194 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_03125 8.5e-102 tnpR L Resolvase, N terminal domain
HPBIMMBF_03128 6e-118 L Initiator Replication protein
HPBIMMBF_03130 5.6e-21 K Firmicute plasmid replication protein (RepL)
HPBIMMBF_03131 4.4e-73
HPBIMMBF_03132 1.1e-99 D Relaxase/Mobilisation nuclease domain
HPBIMMBF_03133 2.4e-61 S Protein of unknown function (DUF2992)
HPBIMMBF_03134 1.1e-53 K Helix-turn-helix XRE-family like proteins
HPBIMMBF_03136 1.2e-27
HPBIMMBF_03137 3.7e-31 S Protein of unknown function (DUF2089)
HPBIMMBF_03138 4.3e-138 K Helix-turn-helix domain
HPBIMMBF_03140 4.7e-29
HPBIMMBF_03141 6.7e-13
HPBIMMBF_03142 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HPBIMMBF_03143 3.1e-22 plnF
HPBIMMBF_03144 6.7e-23
HPBIMMBF_03145 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPBIMMBF_03146 7.5e-242 mesE M Transport protein ComB
HPBIMMBF_03147 1.2e-76 S CAAX protease self-immunity
HPBIMMBF_03148 3.4e-34 S AAA domain
HPBIMMBF_03149 4.2e-39 S AAA domain
HPBIMMBF_03150 7.3e-138 K sequence-specific DNA binding
HPBIMMBF_03151 6.1e-76 K Helix-turn-helix domain
HPBIMMBF_03152 2.2e-11 K Helix-turn-helix domain
HPBIMMBF_03153 2e-169 K Transcriptional regulator
HPBIMMBF_03154 0.0 1.3.5.4 C FMN_bind

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)