ORF_ID e_value Gene_name EC_number CAZy COGs Description
CMHHHLFP_00001 9.5e-68 S Domain of unknown function (DUF1934)
CMHHHLFP_00002 3.3e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CMHHHLFP_00003 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMHHHLFP_00004 1.8e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMHHHLFP_00005 1.9e-109 pipD E Dipeptidase
CMHHHLFP_00006 4.4e-160 pipD E Dipeptidase
CMHHHLFP_00007 7.4e-160 msmR K AraC-like ligand binding domain
CMHHHLFP_00008 7e-107 S Protein of unknown function (DUF1211)
CMHHHLFP_00009 5.2e-221 pbuX F xanthine permease
CMHHHLFP_00010 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMHHHLFP_00011 1.5e-135 K DNA-binding helix-turn-helix protein
CMHHHLFP_00012 7.5e-172 K Helix-turn-helix
CMHHHLFP_00013 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CMHHHLFP_00014 2.5e-155 cylA V ABC transporter
CMHHHLFP_00015 4e-148 cylB V ABC-2 type transporter
CMHHHLFP_00016 1.3e-73 K LytTr DNA-binding domain
CMHHHLFP_00017 2.7e-43 S Protein of unknown function (DUF3021)
CMHHHLFP_00018 1.9e-89 XK27_09675 K Acetyltransferase (GNAT) domain
CMHHHLFP_00019 7e-135 S B3 4 domain
CMHHHLFP_00020 5.4e-90 lmrB P Belongs to the major facilitator superfamily
CMHHHLFP_00021 1.6e-32 P Belongs to the major facilitator superfamily
CMHHHLFP_00022 1.9e-30
CMHHHLFP_00023 7.7e-82 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMHHHLFP_00024 2.5e-28 K NAD+ binding
CMHHHLFP_00026 2.1e-96
CMHHHLFP_00027 3.7e-51
CMHHHLFP_00028 6.7e-44
CMHHHLFP_00029 1.3e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMHHHLFP_00030 1.1e-300 ybeC E amino acid
CMHHHLFP_00031 3.7e-159 G Sucrose-6F-phosphate phosphohydrolase
CMHHHLFP_00032 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
CMHHHLFP_00033 1.9e-39 rpmE2 J Ribosomal protein L31
CMHHHLFP_00034 7.7e-263 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMHHHLFP_00035 3.9e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CMHHHLFP_00036 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMHHHLFP_00037 1.4e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMHHHLFP_00038 5.8e-129 S (CBS) domain
CMHHHLFP_00039 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CMHHHLFP_00040 1.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMHHHLFP_00041 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMHHHLFP_00042 2.4e-34 yabO J S4 domain protein
CMHHHLFP_00043 1.1e-57 divIC D Septum formation initiator
CMHHHLFP_00044 2.8e-63 yabR J S1 RNA binding domain
CMHHHLFP_00045 2.2e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMHHHLFP_00046 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMHHHLFP_00047 2.6e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMHHHLFP_00048 1.4e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMHHHLFP_00049 1.5e-302 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CMHHHLFP_00050 7.8e-08
CMHHHLFP_00051 7.8e-08
CMHHHLFP_00053 4.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
CMHHHLFP_00054 0.0 sdrF M domain protein
CMHHHLFP_00055 3.4e-74 S Protein of unknown function (DUF3290)
CMHHHLFP_00056 1.5e-115 yviA S Protein of unknown function (DUF421)
CMHHHLFP_00057 1.4e-155 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CMHHHLFP_00058 1.9e-183 dnaQ 2.7.7.7 L EXOIII
CMHHHLFP_00059 1.6e-157 endA F DNA RNA non-specific endonuclease
CMHHHLFP_00060 2.8e-284 pipD E Dipeptidase
CMHHHLFP_00061 7.1e-203 malK P ATPases associated with a variety of cellular activities
CMHHHLFP_00062 2.2e-154 gtsB P ABC-type sugar transport systems, permease components
CMHHHLFP_00063 9.4e-147 gtsC P Binding-protein-dependent transport system inner membrane component
CMHHHLFP_00064 3.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
CMHHHLFP_00065 1.3e-235 G Bacterial extracellular solute-binding protein
CMHHHLFP_00066 4e-154 corA P CorA-like Mg2+ transporter protein
CMHHHLFP_00067 1.5e-148 3.5.2.6 V Beta-lactamase enzyme family
CMHHHLFP_00068 2.3e-96 yobS K Bacterial regulatory proteins, tetR family
CMHHHLFP_00069 0.0 ydgH S MMPL family
CMHHHLFP_00070 2.4e-163
CMHHHLFP_00071 0.0 fhaB M Rib/alpha-like repeat
CMHHHLFP_00072 0.0 fhaB M Rib/alpha-like repeat
CMHHHLFP_00073 2.1e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
CMHHHLFP_00074 2.1e-93 F Nucleoside 2-deoxyribosyltransferase
CMHHHLFP_00075 4.5e-160 hipB K Helix-turn-helix
CMHHHLFP_00076 3.2e-152 I alpha/beta hydrolase fold
CMHHHLFP_00077 1.8e-110 yjbF S SNARE associated Golgi protein
CMHHHLFP_00078 1.4e-101 J Acetyltransferase (GNAT) domain
CMHHHLFP_00079 1.8e-253 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMHHHLFP_00080 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMHHHLFP_00081 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CMHHHLFP_00082 1.4e-23
CMHHHLFP_00083 6.4e-116 rsmC 2.1.1.172 J Methyltransferase
CMHHHLFP_00084 1.5e-123 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
CMHHHLFP_00085 2.2e-47 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMHHHLFP_00086 1.6e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMHHHLFP_00087 2.2e-10
CMHHHLFP_00088 2.2e-210 yfdV S Membrane transport protein
CMHHHLFP_00089 2e-118 phoU P Plays a role in the regulation of phosphate uptake
CMHHHLFP_00090 7e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMHHHLFP_00091 4.2e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMHHHLFP_00092 2.6e-155 pstA P Phosphate transport system permease protein PstA
CMHHHLFP_00093 5.2e-176 pstC P probably responsible for the translocation of the substrate across the membrane
CMHHHLFP_00094 1.5e-158 pstS P Phosphate
CMHHHLFP_00095 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMHHHLFP_00096 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMHHHLFP_00097 6.2e-102 nusG K Participates in transcription elongation, termination and antitermination
CMHHHLFP_00098 7.8e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CMHHHLFP_00099 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMHHHLFP_00100 8.1e-173 K helix_turn_helix, arabinose operon control protein
CMHHHLFP_00101 3.7e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
CMHHHLFP_00102 3.5e-114
CMHHHLFP_00103 2.2e-34
CMHHHLFP_00104 3.5e-94 sigH K Belongs to the sigma-70 factor family
CMHHHLFP_00105 1.6e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMHHHLFP_00106 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CMHHHLFP_00107 6.8e-278 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMHHHLFP_00108 9.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMHHHLFP_00109 9.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMHHHLFP_00110 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
CMHHHLFP_00111 7e-52
CMHHHLFP_00112 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
CMHHHLFP_00113 6.4e-184 S AAA domain
CMHHHLFP_00114 2.4e-80 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMHHHLFP_00115 2.2e-19
CMHHHLFP_00116 2.1e-163 czcD P cation diffusion facilitator family transporter
CMHHHLFP_00117 0.0 L Type III restriction enzyme, res subunit
CMHHHLFP_00119 6.8e-144 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CMHHHLFP_00120 7.1e-231 amtB P ammonium transporter
CMHHHLFP_00121 4.3e-62
CMHHHLFP_00122 0.0 lhr L DEAD DEAH box helicase
CMHHHLFP_00123 1.4e-253 P P-loop Domain of unknown function (DUF2791)
CMHHHLFP_00124 0.0 S TerB-C domain
CMHHHLFP_00125 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
CMHHHLFP_00126 2.1e-70 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
CMHHHLFP_00127 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
CMHHHLFP_00128 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMHHHLFP_00129 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMHHHLFP_00130 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CMHHHLFP_00131 9.2e-248 cycA E Amino acid permease
CMHHHLFP_00132 3.9e-69 S transferase hexapeptide repeat
CMHHHLFP_00133 3.7e-160 K Transcriptional regulator
CMHHHLFP_00134 4e-65 manO S Domain of unknown function (DUF956)
CMHHHLFP_00135 6.3e-176 manN G system, mannose fructose sorbose family IID component
CMHHHLFP_00136 2.5e-136 manY G PTS system
CMHHHLFP_00137 4.2e-189 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
CMHHHLFP_00139 1.3e-304 V ABC transporter, ATP-binding protein
CMHHHLFP_00140 2e-138 XK27_01040 S Protein of unknown function (DUF1129)
CMHHHLFP_00141 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMHHHLFP_00142 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
CMHHHLFP_00143 3.4e-155 spo0J K Belongs to the ParB family
CMHHHLFP_00144 1.3e-137 soj D Sporulation initiation inhibitor
CMHHHLFP_00145 7.2e-147 noc K Belongs to the ParB family
CMHHHLFP_00146 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
CMHHHLFP_00147 7.9e-54 cvpA S Colicin V production protein
CMHHHLFP_00148 3.5e-182 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMHHHLFP_00149 2.5e-149 3.1.3.48 T Tyrosine phosphatase family
CMHHHLFP_00150 3.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
CMHHHLFP_00151 7.6e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
CMHHHLFP_00152 1.3e-111 K WHG domain
CMHHHLFP_00153 6.9e-19
CMHHHLFP_00154 1.1e-277 pipD E Dipeptidase
CMHHHLFP_00155 9.8e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
CMHHHLFP_00156 1.3e-180 hrtB V ABC transporter permease
CMHHHLFP_00157 4.8e-96 ygfC K Bacterial regulatory proteins, tetR family
CMHHHLFP_00158 2.4e-112 3.1.3.73 G phosphoglycerate mutase
CMHHHLFP_00159 2e-140 aroD S Alpha/beta hydrolase family
CMHHHLFP_00160 2e-143 S Belongs to the UPF0246 family
CMHHHLFP_00161 3.8e-119
CMHHHLFP_00162 1.1e-157 2.7.7.12 C Domain of unknown function (DUF4931)
CMHHHLFP_00163 9.3e-220 S Putative peptidoglycan binding domain
CMHHHLFP_00164 2.6e-26
CMHHHLFP_00165 1.3e-252 dtpT U amino acid peptide transporter
CMHHHLFP_00166 0.0 pepN 3.4.11.2 E aminopeptidase
CMHHHLFP_00167 4.5e-61 lysM M LysM domain
CMHHHLFP_00168 4.7e-177
CMHHHLFP_00169 1.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMHHHLFP_00170 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMHHHLFP_00171 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMHHHLFP_00172 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CMHHHLFP_00173 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMHHHLFP_00174 4.6e-106 rplD J Forms part of the polypeptide exit tunnel
CMHHHLFP_00175 1.2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMHHHLFP_00176 4.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMHHHLFP_00177 9.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMHHHLFP_00178 3.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMHHHLFP_00179 4.9e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMHHHLFP_00180 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMHHHLFP_00181 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
CMHHHLFP_00182 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMHHHLFP_00183 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMHHHLFP_00184 4.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMHHHLFP_00185 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMHHHLFP_00186 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMHHHLFP_00187 9.3e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMHHHLFP_00188 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMHHHLFP_00189 2.1e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMHHHLFP_00190 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMHHHLFP_00191 2.3e-24 rpmD J Ribosomal protein L30
CMHHHLFP_00192 2e-71 rplO J Binds to the 23S rRNA
CMHHHLFP_00193 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMHHHLFP_00194 2e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMHHHLFP_00195 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMHHHLFP_00196 2.7e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CMHHHLFP_00197 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMHHHLFP_00198 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMHHHLFP_00199 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMHHHLFP_00200 8.2e-61 rplQ J Ribosomal protein L17
CMHHHLFP_00201 2.8e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMHHHLFP_00202 2.4e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMHHHLFP_00203 9.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMHHHLFP_00204 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMHHHLFP_00205 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMHHHLFP_00206 3.5e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
CMHHHLFP_00207 1e-198 L Phage integrase family
CMHHHLFP_00208 1.2e-112
CMHHHLFP_00209 2.9e-285 V ABC transporter transmembrane region
CMHHHLFP_00210 1.8e-153 S hydrolase
CMHHHLFP_00211 5.3e-72 K helix_turn_helix multiple antibiotic resistance protein
CMHHHLFP_00212 0.0 lmrA 3.6.3.44 V ABC transporter
CMHHHLFP_00213 1.9e-59 S Enterocin A Immunity
CMHHHLFP_00214 1.3e-137 glcR K DeoR C terminal sensor domain
CMHHHLFP_00215 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CMHHHLFP_00216 5.3e-161 rssA S Phospholipase, patatin family
CMHHHLFP_00217 3.8e-224 2.7.13.3 T GHKL domain
CMHHHLFP_00218 5e-145 K LytTr DNA-binding domain
CMHHHLFP_00219 3.4e-222 S CAAX protease self-immunity
CMHHHLFP_00220 2.3e-153 S hydrolase
CMHHHLFP_00221 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
CMHHHLFP_00222 7.6e-149 glvR K Helix-turn-helix domain, rpiR family
CMHHHLFP_00223 2.9e-82
CMHHHLFP_00224 1.1e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CMHHHLFP_00225 1.9e-40
CMHHHLFP_00226 1.6e-120 C nitroreductase
CMHHHLFP_00227 1.1e-248 yhdP S Transporter associated domain
CMHHHLFP_00228 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CMHHHLFP_00229 2.3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CMHHHLFP_00230 1.5e-164 phnD P Phosphonate ABC transporter
CMHHHLFP_00231 1.6e-85 uspA T universal stress protein
CMHHHLFP_00232 2.2e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
CMHHHLFP_00233 1.1e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHHHLFP_00234 1.8e-89 ntd 2.4.2.6 F Nucleoside
CMHHHLFP_00235 5.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMHHHLFP_00236 0.0 G Belongs to the glycosyl hydrolase 31 family
CMHHHLFP_00237 5.6e-160 I alpha/beta hydrolase fold
CMHHHLFP_00238 2.4e-131 yibF S overlaps another CDS with the same product name
CMHHHLFP_00239 4.4e-203 yibE S overlaps another CDS with the same product name
CMHHHLFP_00240 7.2e-90
CMHHHLFP_00241 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CMHHHLFP_00242 6.6e-229 S Cysteine-rich secretory protein family
CMHHHLFP_00243 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMHHHLFP_00244 1.4e-257 glnPH2 P ABC transporter permease
CMHHHLFP_00245 2.1e-130
CMHHHLFP_00246 2.2e-125 luxT K Bacterial regulatory proteins, tetR family
CMHHHLFP_00247 2e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMHHHLFP_00248 1.6e-76 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
CMHHHLFP_00249 2.3e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CMHHHLFP_00250 2.1e-182 S Oxidoreductase family, NAD-binding Rossmann fold
CMHHHLFP_00251 4.9e-128 yegW K UTRA
CMHHHLFP_00252 6.5e-234 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CMHHHLFP_00253 4.3e-266 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CMHHHLFP_00254 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
CMHHHLFP_00255 0.0 uup S ABC transporter, ATP-binding protein
CMHHHLFP_00256 1.3e-111 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMHHHLFP_00257 1e-184 scrR K helix_turn _helix lactose operon repressor
CMHHHLFP_00258 5.6e-296 scrB 3.2.1.26 GH32 G invertase
CMHHHLFP_00259 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
CMHHHLFP_00260 5.8e-75
CMHHHLFP_00261 1.1e-77 XK27_02470 K LytTr DNA-binding domain
CMHHHLFP_00262 6.9e-128 liaI S membrane
CMHHHLFP_00263 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMHHHLFP_00264 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMHHHLFP_00265 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMHHHLFP_00266 1.3e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMHHHLFP_00267 5.9e-35 yaaA S S4 domain protein YaaA
CMHHHLFP_00268 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMHHHLFP_00269 1.3e-246 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMHHHLFP_00270 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
CMHHHLFP_00271 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMHHHLFP_00272 5.1e-151 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMHHHLFP_00273 3.9e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMHHHLFP_00274 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CMHHHLFP_00275 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CMHHHLFP_00276 5.8e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMHHHLFP_00277 1.1e-281 clcA P chloride
CMHHHLFP_00278 1.2e-213
CMHHHLFP_00279 1.5e-18
CMHHHLFP_00280 5.5e-118 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
CMHHHLFP_00281 2.4e-130 WQ51_05710 S Mitochondrial biogenesis AIM24
CMHHHLFP_00282 2.7e-175 XK27_05540 S DUF218 domain
CMHHHLFP_00283 2.1e-109 copA 3.6.3.54 P P-type ATPase
CMHHHLFP_00284 4e-14 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CMHHHLFP_00285 1.4e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMHHHLFP_00286 6.1e-188 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CMHHHLFP_00287 1.2e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMHHHLFP_00288 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMHHHLFP_00289 2.9e-223 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CMHHHLFP_00290 7.2e-214 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
CMHHHLFP_00291 2.8e-287 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
CMHHHLFP_00292 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CMHHHLFP_00293 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
CMHHHLFP_00294 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CMHHHLFP_00295 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMHHHLFP_00296 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CMHHHLFP_00297 1.1e-90 S Short repeat of unknown function (DUF308)
CMHHHLFP_00298 4.8e-165 rapZ S Displays ATPase and GTPase activities
CMHHHLFP_00299 8.1e-196 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CMHHHLFP_00300 6.8e-170 whiA K May be required for sporulation
CMHHHLFP_00301 4.7e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMHHHLFP_00302 0.0 S SH3-like domain
CMHHHLFP_00303 1.3e-276 ycaM E amino acid
CMHHHLFP_00305 8.6e-190 cggR K Putative sugar-binding domain
CMHHHLFP_00306 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMHHHLFP_00307 3.5e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CMHHHLFP_00308 9.9e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMHHHLFP_00309 1.3e-96
CMHHHLFP_00310 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
CMHHHLFP_00311 2.6e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMHHHLFP_00312 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CMHHHLFP_00313 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
CMHHHLFP_00314 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
CMHHHLFP_00315 2.4e-164 murB 1.3.1.98 M Cell wall formation
CMHHHLFP_00316 9.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CMHHHLFP_00317 1.1e-136 potB P ABC transporter permease
CMHHHLFP_00318 2.9e-132 potC P ABC transporter permease
CMHHHLFP_00319 1e-206 potD P ABC transporter
CMHHHLFP_00320 1.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMHHHLFP_00321 1.2e-172 ybbR S YbbR-like protein
CMHHHLFP_00322 3.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMHHHLFP_00323 1.3e-148 S hydrolase
CMHHHLFP_00324 1.3e-145 S Sucrose-6F-phosphate phosphohydrolase
CMHHHLFP_00325 1e-120
CMHHHLFP_00326 1.7e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMHHHLFP_00327 6.7e-212 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CMHHHLFP_00328 3.4e-152 licT K CAT RNA binding domain
CMHHHLFP_00329 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMHHHLFP_00330 3.1e-286 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMHHHLFP_00331 4.2e-175 D Alpha beta
CMHHHLFP_00332 0.0 E Amino acid permease
CMHHHLFP_00334 2.2e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMHHHLFP_00335 1.9e-92 S VanZ like family
CMHHHLFP_00336 2e-132 yebC K Transcriptional regulatory protein
CMHHHLFP_00337 5.4e-178 comGA NU Type II IV secretion system protein
CMHHHLFP_00338 9.9e-175 comGB NU type II secretion system
CMHHHLFP_00339 2.4e-46 comGC U competence protein ComGC
CMHHHLFP_00340 2e-71
CMHHHLFP_00341 1e-19
CMHHHLFP_00342 1.3e-86 comGF U Putative Competence protein ComGF
CMHHHLFP_00343 3e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
CMHHHLFP_00344 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMHHHLFP_00346 4.3e-121 M Protein of unknown function (DUF3737)
CMHHHLFP_00347 8.1e-176 patB 4.4.1.8 E Aminotransferase, class I
CMHHHLFP_00348 5.7e-29 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CMHHHLFP_00349 2.3e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
CMHHHLFP_00350 4.9e-61 S SdpI/YhfL protein family
CMHHHLFP_00351 2.2e-131 K Transcriptional regulatory protein, C terminal
CMHHHLFP_00352 6.2e-271 T PhoQ Sensor
CMHHHLFP_00353 1.6e-61 limB 1.14.13.107, 1.14.13.162 C Luciferase-like monooxygenase
CMHHHLFP_00354 2.2e-123 XK27_00915 C Luciferase-like monooxygenase
CMHHHLFP_00355 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMHHHLFP_00356 4.1e-107 vanZ V VanZ like family
CMHHHLFP_00357 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
CMHHHLFP_00358 9.9e-250 EGP Major facilitator Superfamily
CMHHHLFP_00359 1.6e-196 ampC V Beta-lactamase
CMHHHLFP_00362 2e-64
CMHHHLFP_00363 2.9e-287 S DNA primase
CMHHHLFP_00364 1.6e-35
CMHHHLFP_00365 1.9e-33
CMHHHLFP_00366 8.1e-69
CMHHHLFP_00367 1.4e-36
CMHHHLFP_00368 2.9e-12 S Helix-turn-helix domain
CMHHHLFP_00369 3.2e-58 K Transcriptional
CMHHHLFP_00370 9.5e-208 sip L Belongs to the 'phage' integrase family
CMHHHLFP_00371 2e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
CMHHHLFP_00372 4.5e-114 tdk 2.7.1.21 F thymidine kinase
CMHHHLFP_00373 3.4e-181 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMHHHLFP_00374 7.8e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMHHHLFP_00375 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CMHHHLFP_00376 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMHHHLFP_00377 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
CMHHHLFP_00378 6.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMHHHLFP_00379 1.7e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMHHHLFP_00380 1.5e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMHHHLFP_00381 4.3e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMHHHLFP_00382 9.8e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMHHHLFP_00383 2.1e-255 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMHHHLFP_00384 6.9e-64 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CMHHHLFP_00385 2.6e-30 ywzB S Protein of unknown function (DUF1146)
CMHHHLFP_00386 1.9e-178 mbl D Cell shape determining protein MreB Mrl
CMHHHLFP_00387 2.5e-49 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CMHHHLFP_00388 1.5e-33 S Protein of unknown function (DUF2969)
CMHHHLFP_00389 9.5e-217 rodA D Belongs to the SEDS family
CMHHHLFP_00390 5.8e-77 uspA T universal stress protein
CMHHHLFP_00391 4e-33
CMHHHLFP_00392 4.2e-242 rarA L recombination factor protein RarA
CMHHHLFP_00393 1.9e-83 yueI S Protein of unknown function (DUF1694)
CMHHHLFP_00394 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMHHHLFP_00395 1.5e-292 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CMHHHLFP_00396 1.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
CMHHHLFP_00397 5.9e-230 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMHHHLFP_00398 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMHHHLFP_00399 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMHHHLFP_00400 8.5e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CMHHHLFP_00401 8.9e-127 S Haloacid dehalogenase-like hydrolase
CMHHHLFP_00402 1.2e-114 radC L DNA repair protein
CMHHHLFP_00403 1.1e-176 mreB D cell shape determining protein MreB
CMHHHLFP_00404 7.2e-150 mreC M Involved in formation and maintenance of cell shape
CMHHHLFP_00405 7.1e-95 mreD
CMHHHLFP_00406 8.8e-10 S Protein of unknown function (DUF4044)
CMHHHLFP_00407 3.2e-53 S Protein of unknown function (DUF3397)
CMHHHLFP_00408 4e-72 mraZ K Belongs to the MraZ family
CMHHHLFP_00409 2.2e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMHHHLFP_00410 2.4e-54 ftsL D Cell division protein FtsL
CMHHHLFP_00411 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CMHHHLFP_00412 2.1e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMHHHLFP_00413 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMHHHLFP_00414 4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMHHHLFP_00415 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CMHHHLFP_00416 2.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CMHHHLFP_00417 4.2e-245 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMHHHLFP_00418 2.1e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CMHHHLFP_00419 7.8e-29 yggT S YGGT family
CMHHHLFP_00420 6.7e-150 ylmH S S4 domain protein
CMHHHLFP_00421 1.9e-75 gpsB D DivIVA domain protein
CMHHHLFP_00422 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMHHHLFP_00423 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
CMHHHLFP_00424 8.9e-104 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
CMHHHLFP_00425 3.4e-28
CMHHHLFP_00426 5.9e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMHHHLFP_00427 9.8e-58 XK27_04120 S Putative amino acid metabolism
CMHHHLFP_00428 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CMHHHLFP_00429 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
CMHHHLFP_00430 5.7e-115 S Repeat protein
CMHHHLFP_00431 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMHHHLFP_00432 3.7e-304 L Nuclease-related domain
CMHHHLFP_00433 9.3e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CMHHHLFP_00434 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMHHHLFP_00435 3.2e-33 ykzG S Belongs to the UPF0356 family
CMHHHLFP_00436 1.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMHHHLFP_00437 0.0 typA T GTP-binding protein TypA
CMHHHLFP_00438 7.7e-211 ftsW D Belongs to the SEDS family
CMHHHLFP_00439 4.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
CMHHHLFP_00440 4.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
CMHHHLFP_00441 6.2e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMHHHLFP_00442 7.6e-194 ylbL T Belongs to the peptidase S16 family
CMHHHLFP_00443 1.7e-72 comEA L Competence protein ComEA
CMHHHLFP_00444 0.0 comEC S Competence protein ComEC
CMHHHLFP_00445 8.8e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
CMHHHLFP_00446 3e-35 rpsT J Binds directly to 16S ribosomal RNA
CMHHHLFP_00447 1.1e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMHHHLFP_00448 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMHHHLFP_00449 2.2e-151
CMHHHLFP_00450 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMHHHLFP_00451 3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMHHHLFP_00452 1.2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMHHHLFP_00453 2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
CMHHHLFP_00454 8.9e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CMHHHLFP_00455 2.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
CMHHHLFP_00456 2.9e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMHHHLFP_00457 5.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CMHHHLFP_00458 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CMHHHLFP_00459 3.7e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMHHHLFP_00460 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CMHHHLFP_00461 5.3e-220 aspC 2.6.1.1 E Aminotransferase
CMHHHLFP_00462 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMHHHLFP_00463 9.2e-206 pbpX1 V Beta-lactamase
CMHHHLFP_00464 1.3e-298 I Protein of unknown function (DUF2974)
CMHHHLFP_00465 8.6e-41 C FMN_bind
CMHHHLFP_00466 1.6e-80
CMHHHLFP_00467 1.9e-286
CMHHHLFP_00468 5.2e-178 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
CMHHHLFP_00469 2.7e-16 adhC 1.1.1.90 C S-(hydroxymethyl)glutathione dehydrogenase activity
CMHHHLFP_00470 8.5e-145
CMHHHLFP_00471 2.7e-10
CMHHHLFP_00474 6.1e-19 alkD L DNA alkylation repair enzyme
CMHHHLFP_00475 1.5e-67 alkD L DNA alkylation repair enzyme
CMHHHLFP_00476 6e-39 S Transglycosylase associated protein
CMHHHLFP_00478 2.4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMHHHLFP_00479 2.2e-128 K UTRA domain
CMHHHLFP_00480 4.5e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
CMHHHLFP_00481 6.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
CMHHHLFP_00482 1.2e-80
CMHHHLFP_00483 4.4e-138 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHHHLFP_00484 1.2e-70 S Domain of unknown function (DUF3284)
CMHHHLFP_00485 6.3e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMHHHLFP_00486 4.7e-134 gmuR K UTRA
CMHHHLFP_00487 3.5e-41
CMHHHLFP_00488 2.4e-267 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHHHLFP_00489 9.5e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMHHHLFP_00490 6.8e-156 ypbG 2.7.1.2 GK ROK family
CMHHHLFP_00491 1.6e-85 C Nitroreductase family
CMHHHLFP_00492 1.3e-108 S Domain of unknown function (DUF4767)
CMHHHLFP_00493 8.1e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMHHHLFP_00494 6.8e-153 yitS S Uncharacterised protein, DegV family COG1307
CMHHHLFP_00495 1.7e-99 3.6.1.27 I Acid phosphatase homologues
CMHHHLFP_00496 8.7e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMHHHLFP_00498 4.3e-180 L Belongs to the 'phage' integrase family
CMHHHLFP_00499 2.4e-11
CMHHHLFP_00500 5.8e-83
CMHHHLFP_00502 1.2e-55 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
CMHHHLFP_00503 4.4e-29 2.3.1.19 K Helix-turn-helix XRE-family like proteins
CMHHHLFP_00504 8.1e-252 yifK E Amino acid permease
CMHHHLFP_00505 6.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMHHHLFP_00506 5.6e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMHHHLFP_00507 0.0 aha1 P E1-E2 ATPase
CMHHHLFP_00508 5e-159 metQ1 P Belongs to the nlpA lipoprotein family
CMHHHLFP_00509 2.2e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMHHHLFP_00510 7.6e-81 metI P ABC transporter permease
CMHHHLFP_00511 2e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CMHHHLFP_00512 2e-266 frdC 1.3.5.4 C FAD binding domain
CMHHHLFP_00513 8e-293 M domain protein
CMHHHLFP_00514 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CMHHHLFP_00515 1.2e-257 pepC 3.4.22.40 E Peptidase C1-like family
CMHHHLFP_00516 1.2e-274 P Sodium:sulfate symporter transmembrane region
CMHHHLFP_00517 1.1e-155 ydjP I Alpha/beta hydrolase family
CMHHHLFP_00518 8.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CMHHHLFP_00519 4.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
CMHHHLFP_00520 1.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
CMHHHLFP_00521 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
CMHHHLFP_00522 9.3e-72 yeaL S Protein of unknown function (DUF441)
CMHHHLFP_00523 3.3e-13
CMHHHLFP_00524 3.8e-148 cbiQ P cobalt transport
CMHHHLFP_00525 0.0 ykoD P ABC transporter, ATP-binding protein
CMHHHLFP_00526 7.4e-95 S UPF0397 protein
CMHHHLFP_00527 1.3e-63 S Domain of unknown function DUF1828
CMHHHLFP_00528 2.2e-54
CMHHHLFP_00529 1.2e-177 citR K Putative sugar-binding domain
CMHHHLFP_00530 5.5e-245 yjjP S Putative threonine/serine exporter
CMHHHLFP_00531 1.5e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMHHHLFP_00532 2.1e-174 prmA J Ribosomal protein L11 methyltransferase
CMHHHLFP_00533 4e-49
CMHHHLFP_00534 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMHHHLFP_00535 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMHHHLFP_00536 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
CMHHHLFP_00537 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CMHHHLFP_00538 2.5e-225 patA 2.6.1.1 E Aminotransferase
CMHHHLFP_00539 2.8e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMHHHLFP_00540 3.5e-154 S reductase
CMHHHLFP_00541 1.6e-151 yxeH S hydrolase
CMHHHLFP_00542 3.1e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMHHHLFP_00543 3.9e-230 yfnA E Amino Acid
CMHHHLFP_00544 2.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
CMHHHLFP_00545 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMHHHLFP_00546 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMHHHLFP_00547 0.0 I Acyltransferase
CMHHHLFP_00548 2.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CMHHHLFP_00549 7.2e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CMHHHLFP_00550 5.1e-32 yrvD S Lipopolysaccharide assembly protein A domain
CMHHHLFP_00551 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CMHHHLFP_00552 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CMHHHLFP_00554 0.0 dnaE 2.7.7.7 L DNA polymerase
CMHHHLFP_00555 7.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CMHHHLFP_00556 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CMHHHLFP_00557 5e-170 cvfB S S1 domain
CMHHHLFP_00558 1.6e-168 xerD D recombinase XerD
CMHHHLFP_00559 1.7e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMHHHLFP_00560 1.3e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMHHHLFP_00561 3.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMHHHLFP_00562 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMHHHLFP_00563 2.2e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMHHHLFP_00564 1.1e-46 M Lysin motif
CMHHHLFP_00565 8.4e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CMHHHLFP_00566 2.3e-202 rpsA 1.17.7.4 J Ribosomal protein S1
CMHHHLFP_00567 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CMHHHLFP_00568 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMHHHLFP_00569 2.1e-230 S Tetratricopeptide repeat protein
CMHHHLFP_00570 1.3e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMHHHLFP_00571 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CMHHHLFP_00572 1.2e-107 hlyIII S protein, hemolysin III
CMHHHLFP_00573 2.1e-149 DegV S Uncharacterised protein, DegV family COG1307
CMHHHLFP_00574 2.7e-35 yozE S Belongs to the UPF0346 family
CMHHHLFP_00575 3.5e-283 yjcE P Sodium proton antiporter
CMHHHLFP_00576 1e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CMHHHLFP_00577 1.1e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMHHHLFP_00578 3.6e-157 dprA LU DNA protecting protein DprA
CMHHHLFP_00579 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMHHHLFP_00580 6.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMHHHLFP_00581 7.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
CMHHHLFP_00582 1.1e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CMHHHLFP_00583 1.7e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMHHHLFP_00584 1.8e-180 lacX 5.1.3.3 G Aldose 1-epimerase
CMHHHLFP_00585 1.5e-65
CMHHHLFP_00586 3.8e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHHHLFP_00587 3.2e-158 S Alpha/beta hydrolase of unknown function (DUF915)
CMHHHLFP_00588 1.4e-150 xerD L Phage integrase, N-terminal SAM-like domain
CMHHHLFP_00589 3.5e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMHHHLFP_00590 1.1e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMHHHLFP_00591 6.9e-275 pepV 3.5.1.18 E dipeptidase PepV
CMHHHLFP_00592 5.3e-286 E Amino acid permease
CMHHHLFP_00593 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
CMHHHLFP_00594 3.2e-247 ynbB 4.4.1.1 P aluminum resistance
CMHHHLFP_00595 3.9e-119 ktrA P domain protein
CMHHHLFP_00596 4e-240 ktrB P Potassium uptake protein
CMHHHLFP_00597 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
CMHHHLFP_00598 1.7e-81 C Flavodoxin
CMHHHLFP_00599 0.0 uvrA3 L excinuclease ABC, A subunit
CMHHHLFP_00600 5.9e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
CMHHHLFP_00601 1.8e-113 3.6.1.27 I Acid phosphatase homologues
CMHHHLFP_00602 4.5e-67 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMHHHLFP_00603 1.9e-208 pbpX1 V Beta-lactamase
CMHHHLFP_00604 1.5e-155 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
CMHHHLFP_00605 3.1e-93 S ECF-type riboflavin transporter, S component
CMHHHLFP_00606 2.1e-216 S Putative peptidoglycan binding domain
CMHHHLFP_00607 6.5e-241
CMHHHLFP_00608 0.0 treB 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMHHHLFP_00609 2.9e-128 treR K UTRA
CMHHHLFP_00610 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
CMHHHLFP_00611 2.8e-128 M Glycosyl transferases group 1
CMHHHLFP_00612 3.8e-99 UW LPXTG-motif cell wall anchor domain protein
CMHHHLFP_00613 2.4e-164 M domain protein
CMHHHLFP_00614 2.6e-21 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
CMHHHLFP_00615 0.0 UW LPXTG-motif cell wall anchor domain protein
CMHHHLFP_00616 0.0 UW LPXTG-motif cell wall anchor domain protein
CMHHHLFP_00617 1.2e-28 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CMHHHLFP_00618 8.8e-164 rocF 3.5.3.1, 3.5.3.11 E Arginase family
CMHHHLFP_00619 2.1e-114 ylbE GM NAD dependent epimerase dehydratase family protein
CMHHHLFP_00620 6.6e-159 K Transcriptional regulator
CMHHHLFP_00621 7.7e-168 S Oxidoreductase, aldo keto reductase family protein
CMHHHLFP_00622 4.3e-166 akr5f 1.1.1.346 S reductase
CMHHHLFP_00623 2.7e-165 yvgN C Aldo keto reductase
CMHHHLFP_00624 4.1e-217 S SLAP domain
CMHHHLFP_00625 4.1e-103 yyaR K Acetyltransferase (GNAT) domain
CMHHHLFP_00628 6.8e-104
CMHHHLFP_00629 6.8e-78 K Transcriptional regulator
CMHHHLFP_00630 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
CMHHHLFP_00631 3e-164 S reductase
CMHHHLFP_00632 1.3e-170
CMHHHLFP_00633 4.2e-33 K Transcriptional regulator
CMHHHLFP_00634 9.3e-113 papP P ABC transporter, permease protein
CMHHHLFP_00635 2.2e-77 P ABC transporter permease
CMHHHLFP_00636 3.5e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMHHHLFP_00637 7.7e-160 cjaA ET ABC transporter substrate-binding protein
CMHHHLFP_00638 8.3e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CMHHHLFP_00639 8.7e-110 5.4.2.11 G Phosphoglycerate mutase family
CMHHHLFP_00640 3.4e-174 4.1.1.45 S Amidohydrolase
CMHHHLFP_00641 1.1e-29
CMHHHLFP_00642 2.5e-109
CMHHHLFP_00643 4.9e-108
CMHHHLFP_00644 1.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
CMHHHLFP_00645 2.3e-215 ynfM EGP Major facilitator Superfamily
CMHHHLFP_00646 1e-153 K Bacterial regulatory helix-turn-helix protein, lysR family
CMHHHLFP_00647 8.2e-119 3.6.1.55 F NUDIX domain
CMHHHLFP_00648 1.3e-76
CMHHHLFP_00649 3.6e-87 FG HIT domain
CMHHHLFP_00650 1.1e-62
CMHHHLFP_00651 3.7e-93 rimL J Acetyltransferase (GNAT) domain
CMHHHLFP_00652 1.1e-101 S Alpha/beta hydrolase family
CMHHHLFP_00653 1.1e-150 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
CMHHHLFP_00654 2.3e-116 dedA S SNARE-like domain protein
CMHHHLFP_00655 1.1e-107 S Protein of unknown function (DUF1461)
CMHHHLFP_00656 7.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMHHHLFP_00657 1.3e-81 yutD S Protein of unknown function (DUF1027)
CMHHHLFP_00658 5.2e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CMHHHLFP_00659 1.9e-55
CMHHHLFP_00660 3.9e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CMHHHLFP_00661 2.9e-182 ccpA K catabolite control protein A
CMHHHLFP_00662 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CMHHHLFP_00663 2.1e-45
CMHHHLFP_00664 3.6e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CMHHHLFP_00665 8.2e-130 ykuT M mechanosensitive ion channel
CMHHHLFP_00666 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMHHHLFP_00667 3.8e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CMHHHLFP_00668 5.1e-69 yslB S Protein of unknown function (DUF2507)
CMHHHLFP_00669 4e-36 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CMHHHLFP_00670 6e-54 trxA O Belongs to the thioredoxin family
CMHHHLFP_00671 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMHHHLFP_00672 2.8e-51 yrzB S Belongs to the UPF0473 family
CMHHHLFP_00673 2.7e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMHHHLFP_00674 2e-42 yrzL S Belongs to the UPF0297 family
CMHHHLFP_00675 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMHHHLFP_00676 6e-188 purR13 K Bacterial regulatory proteins, lacI family
CMHHHLFP_00677 1.2e-154 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
CMHHHLFP_00678 1.3e-176 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
CMHHHLFP_00679 1.6e-258 glpK_1 2.7.1.30 G FGGY family of carbohydrate kinases, C-terminal domain
CMHHHLFP_00680 7.4e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMHHHLFP_00681 1.9e-248 lmrB EGP Major facilitator Superfamily
CMHHHLFP_00684 4.1e-152
CMHHHLFP_00685 4e-167
CMHHHLFP_00686 1.8e-116 ybbL S ABC transporter, ATP-binding protein
CMHHHLFP_00687 5.5e-133 ybbM S Uncharacterised protein family (UPF0014)
CMHHHLFP_00688 8.9e-264 glnA 6.3.1.2 E glutamine synthetase
CMHHHLFP_00689 1.9e-239 ynbB 4.4.1.1 P aluminum resistance
CMHHHLFP_00690 2.1e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMHHHLFP_00691 1.3e-76 mutR K Helix-turn-helix XRE-family like proteins
CMHHHLFP_00692 3.2e-97 M CHAP domain
CMHHHLFP_00693 1.5e-68 K Helix-turn-helix XRE-family like proteins
CMHHHLFP_00694 2.7e-120 S CAAX protease self-immunity
CMHHHLFP_00695 1.6e-194 S DUF218 domain
CMHHHLFP_00696 0.0 macB_3 V ABC transporter, ATP-binding protein
CMHHHLFP_00697 1.6e-103 S ECF transporter, substrate-specific component
CMHHHLFP_00698 5.6e-186 tcsA S ABC transporter substrate-binding protein PnrA-like
CMHHHLFP_00699 5.6e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
CMHHHLFP_00700 1.7e-287 xylG 3.6.3.17 S ABC transporter
CMHHHLFP_00701 5.1e-207 yufP S Belongs to the binding-protein-dependent transport system permease family
CMHHHLFP_00702 2.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
CMHHHLFP_00703 1.7e-159 yeaE S Aldo/keto reductase family
CMHHHLFP_00704 2.5e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMHHHLFP_00705 4.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CMHHHLFP_00706 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CMHHHLFP_00707 8.5e-145 cof S haloacid dehalogenase-like hydrolase
CMHHHLFP_00708 1.1e-231 pbuG S permease
CMHHHLFP_00709 9.3e-95 K response regulator
CMHHHLFP_00710 5.8e-195 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
CMHHHLFP_00711 2.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMHHHLFP_00712 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CMHHHLFP_00713 9.4e-49 S Enterocin A Immunity
CMHHHLFP_00714 4e-53 S Enterocin A Immunity
CMHHHLFP_00715 1.5e-33
CMHHHLFP_00716 1.1e-26
CMHHHLFP_00717 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
CMHHHLFP_00718 1.4e-37 S Enterocin A Immunity
CMHHHLFP_00719 1.2e-216 S CAAX protease self-immunity
CMHHHLFP_00720 5.1e-109 S CAAX protease self-immunity
CMHHHLFP_00722 7e-110
CMHHHLFP_00726 2.8e-233 2.7.13.3 T GHKL domain
CMHHHLFP_00727 1.2e-146 K LytTr DNA-binding domain
CMHHHLFP_00729 4.2e-07
CMHHHLFP_00730 9.7e-228 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMHHHLFP_00731 3.4e-106 M Transport protein ComB
CMHHHLFP_00732 8.1e-209 blpT
CMHHHLFP_00737 8.8e-21
CMHHHLFP_00738 9e-90
CMHHHLFP_00739 8.2e-31 yozG K Transcriptional regulator
CMHHHLFP_00740 2.1e-25
CMHHHLFP_00741 4e-69
CMHHHLFP_00742 6.2e-08
CMHHHLFP_00743 2.6e-166 natA S ABC transporter, ATP-binding protein
CMHHHLFP_00744 3.9e-218 natB CP ABC-2 family transporter protein
CMHHHLFP_00745 7.4e-197 fic S Fic/DOC family
CMHHHLFP_00746 2.3e-136 fruR K DeoR C terminal sensor domain
CMHHHLFP_00747 3.3e-169 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CMHHHLFP_00748 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
CMHHHLFP_00749 5.5e-47 S Protein of unknown function (DUF3021)
CMHHHLFP_00750 5.1e-75 K LytTr DNA-binding domain
CMHHHLFP_00752 1.2e-238 I Protein of unknown function (DUF2974)
CMHHHLFP_00753 1e-30
CMHHHLFP_00754 1e-16 S CsbD-like
CMHHHLFP_00755 1.6e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
CMHHHLFP_00756 8.3e-176 degV S DegV family
CMHHHLFP_00757 1.1e-172 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
CMHHHLFP_00758 5.5e-256 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CMHHHLFP_00759 2.1e-71 rplI J Binds to the 23S rRNA
CMHHHLFP_00760 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CMHHHLFP_00761 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMHHHLFP_00762 2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMHHHLFP_00763 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
CMHHHLFP_00764 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMHHHLFP_00765 2e-247 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMHHHLFP_00766 5e-75
CMHHHLFP_00767 3.4e-16
CMHHHLFP_00768 1.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CMHHHLFP_00769 2.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CMHHHLFP_00770 5.6e-57 S Protein conserved in bacteria
CMHHHLFP_00771 2.2e-170 L transposase, IS605 OrfB family
CMHHHLFP_00772 7.6e-134 cobQ S glutamine amidotransferase
CMHHHLFP_00773 9.5e-83 M NlpC/P60 family
CMHHHLFP_00774 1.6e-166 EG EamA-like transporter family
CMHHHLFP_00775 3.2e-167 EG EamA-like transporter family
CMHHHLFP_00776 1.6e-163 yicL EG EamA-like transporter family
CMHHHLFP_00777 3.1e-105
CMHHHLFP_00778 1.5e-56
CMHHHLFP_00779 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMHHHLFP_00780 3.2e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMHHHLFP_00781 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMHHHLFP_00784 8.3e-47 S Alpha/beta hydrolase of unknown function (DUF915)
CMHHHLFP_00785 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMHHHLFP_00786 1.7e-84
CMHHHLFP_00787 2.3e-133 cobB K SIR2 family
CMHHHLFP_00788 1.3e-137 terC P Integral membrane protein TerC family
CMHHHLFP_00789 2.5e-64 yeaO S Protein of unknown function, DUF488
CMHHHLFP_00790 5.5e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CMHHHLFP_00791 1e-293 glnP P ABC transporter permease
CMHHHLFP_00792 2.1e-137 glnQ E ABC transporter, ATP-binding protein
CMHHHLFP_00793 1.2e-182 S Protein of unknown function (DUF805)
CMHHHLFP_00794 4e-161 L HNH nucleases
CMHHHLFP_00795 3.7e-122 yfbR S HD containing hydrolase-like enzyme
CMHHHLFP_00796 1.5e-211 G Glycosyl hydrolases family 8
CMHHHLFP_00797 1.6e-228 ydaM M Glycosyl transferase family group 2
CMHHHLFP_00799 2.8e-48
CMHHHLFP_00800 3.6e-61
CMHHHLFP_00801 2.1e-293 S ABC transporter
CMHHHLFP_00802 4.4e-138 thrE S Putative threonine/serine exporter
CMHHHLFP_00803 7.8e-85 S Threonine/Serine exporter, ThrE
CMHHHLFP_00804 4.6e-35 sufC O FeS assembly ATPase SufC
CMHHHLFP_00805 8.8e-47 sufB O assembly protein SufB
CMHHHLFP_00806 5.2e-53 yitW S Iron-sulfur cluster assembly protein
CMHHHLFP_00807 7.7e-137 yvpB S Peptidase_C39 like family
CMHHHLFP_00808 7.8e-78
CMHHHLFP_00809 1.7e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMHHHLFP_00810 3.8e-78 nrdI F NrdI Flavodoxin like
CMHHHLFP_00811 8.1e-111
CMHHHLFP_00812 1e-279 S O-antigen ligase like membrane protein
CMHHHLFP_00813 5.6e-33
CMHHHLFP_00814 1.8e-85 gmk2 2.7.4.8 F Guanylate kinase homologues.
CMHHHLFP_00815 7.6e-84 M NlpC/P60 family
CMHHHLFP_00816 2.3e-126 M NlpC P60 family protein
CMHHHLFP_00818 2.2e-51 K LysR substrate binding domain
CMHHHLFP_00819 4.2e-56 1.3.5.4 S FMN_bind
CMHHHLFP_00820 2.6e-230 1.3.5.4 C FAD binding domain
CMHHHLFP_00821 5.6e-115 K Transcriptional regulator, LysR family
CMHHHLFP_00822 1.5e-38 S Cytochrome B5
CMHHHLFP_00823 5e-167 arbZ I Phosphate acyltransferases
CMHHHLFP_00824 8.4e-184 arbY M Glycosyl transferase family 8
CMHHHLFP_00825 2.2e-187 arbY M Glycosyl transferase family 8
CMHHHLFP_00826 1.1e-158 arbx M Glycosyl transferase family 8
CMHHHLFP_00827 2.1e-148 arbV 2.3.1.51 I Acyl-transferase
CMHHHLFP_00828 3e-78
CMHHHLFP_00829 2.8e-288 P ABC transporter
CMHHHLFP_00830 1.4e-295 V ABC-type multidrug transport system, ATPase and permease components
CMHHHLFP_00831 0.0 oppA E ABC transporter substrate-binding protein
CMHHHLFP_00832 0.0 oppA E ABC transporter substrate-binding protein
CMHHHLFP_00833 2.9e-144 oppC P Binding-protein-dependent transport system inner membrane component
CMHHHLFP_00834 2.3e-176 oppB P ABC transporter permease
CMHHHLFP_00835 6.1e-177 oppF P Belongs to the ABC transporter superfamily
CMHHHLFP_00836 2.5e-197 oppD P Belongs to the ABC transporter superfamily
CMHHHLFP_00837 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMHHHLFP_00838 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CMHHHLFP_00839 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMHHHLFP_00840 2.4e-306 yloV S DAK2 domain fusion protein YloV
CMHHHLFP_00841 6.8e-57 asp S Asp23 family, cell envelope-related function
CMHHHLFP_00842 3.7e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CMHHHLFP_00843 4.2e-52
CMHHHLFP_00844 6.9e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
CMHHHLFP_00845 4.5e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CMHHHLFP_00846 8e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMHHHLFP_00847 0.0 KLT serine threonine protein kinase
CMHHHLFP_00848 2.3e-139 stp 3.1.3.16 T phosphatase
CMHHHLFP_00849 1.3e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMHHHLFP_00850 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMHHHLFP_00851 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMHHHLFP_00852 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CMHHHLFP_00853 1.5e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
CMHHHLFP_00854 1.8e-80 6.3.3.2 S ASCH
CMHHHLFP_00855 4.7e-310 recN L May be involved in recombinational repair of damaged DNA
CMHHHLFP_00856 3.5e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CMHHHLFP_00857 6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CMHHHLFP_00858 3.4e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMHHHLFP_00859 7.3e-213 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMHHHLFP_00860 1.9e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMHHHLFP_00861 3.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMHHHLFP_00862 6.8e-72 yqhY S Asp23 family, cell envelope-related function
CMHHHLFP_00863 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMHHHLFP_00864 3.2e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CMHHHLFP_00865 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CMHHHLFP_00866 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CMHHHLFP_00867 2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMHHHLFP_00868 6.8e-259 S Uncharacterized protein conserved in bacteria (DUF2325)
CMHHHLFP_00869 1.8e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CMHHHLFP_00870 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CMHHHLFP_00871 1.3e-105 Q Imidazolonepropionase and related amidohydrolases
CMHHHLFP_00872 3.2e-109 Q Imidazolonepropionase and related amidohydrolases
CMHHHLFP_00874 6.7e-60 oppA E ABC transporter
CMHHHLFP_00875 9.2e-98 E ABC transporter
CMHHHLFP_00876 3.7e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
CMHHHLFP_00877 5e-311 S Predicted membrane protein (DUF2207)
CMHHHLFP_00878 3.6e-154 cinI S Serine hydrolase (FSH1)
CMHHHLFP_00879 1.7e-115 M Glycosyl hydrolases family 25
CMHHHLFP_00880 1.6e-74 M Glycosyl hydrolases family 25
CMHHHLFP_00882 1.7e-165 S Membrane
CMHHHLFP_00883 6.5e-178 I Carboxylesterase family
CMHHHLFP_00884 1e-65 arsC 1.20.4.1 P Belongs to the ArsC family
CMHHHLFP_00885 5.2e-295 V ABC-type multidrug transport system, ATPase and permease components
CMHHHLFP_00886 8.5e-290 V ABC-type multidrug transport system, ATPase and permease components
CMHHHLFP_00887 1.5e-152 S haloacid dehalogenase-like hydrolase
CMHHHLFP_00888 1.8e-206
CMHHHLFP_00889 1.2e-163
CMHHHLFP_00890 0.0 lacA 3.2.1.23 G -beta-galactosidase
CMHHHLFP_00891 0.0 yic1 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
CMHHHLFP_00892 7.7e-309 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMHHHLFP_00893 1.1e-166 bglK 2.7.1.2, 2.7.1.85 GK ROK family
CMHHHLFP_00894 7.3e-206 xylR GK ROK family
CMHHHLFP_00895 1.8e-237 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHHHLFP_00896 6.4e-100 S Bacterial PH domain
CMHHHLFP_00897 3.4e-16
CMHHHLFP_00898 4.2e-65 ps301 K sequence-specific DNA binding
CMHHHLFP_00899 2.3e-47 S Motility quorum-sensing regulator, toxin of MqsA
CMHHHLFP_00900 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CMHHHLFP_00901 8.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CMHHHLFP_00902 4.9e-47
CMHHHLFP_00903 6.6e-151 glcU U sugar transport
CMHHHLFP_00904 0.0
CMHHHLFP_00906 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CMHHHLFP_00907 7.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CMHHHLFP_00908 6.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMHHHLFP_00909 8.5e-184 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CMHHHLFP_00910 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMHHHLFP_00911 9.8e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMHHHLFP_00912 1.5e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CMHHHLFP_00913 6.4e-119 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMHHHLFP_00914 1.2e-117 GM NmrA-like family
CMHHHLFP_00915 0.0 3.6.3.8 P P-type ATPase
CMHHHLFP_00916 1.8e-248 clcA P chloride
CMHHHLFP_00917 5.2e-103 O Matrixin
CMHHHLFP_00918 0.0 UW LPXTG-motif cell wall anchor domain protein
CMHHHLFP_00919 8.8e-95 wecD K acetyltransferase
CMHHHLFP_00920 1e-50
CMHHHLFP_00921 1.5e-147 metQ2 P Belongs to the nlpA lipoprotein family
CMHHHLFP_00922 8.8e-47
CMHHHLFP_00923 8.1e-125 sdaAB 4.3.1.17 E Serine dehydratase beta chain
CMHHHLFP_00924 9e-156 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CMHHHLFP_00925 5.7e-52 S Iron-sulfur cluster assembly protein
CMHHHLFP_00926 0.0 oppA E ABC transporter substrate-binding protein
CMHHHLFP_00928 9.1e-264 npr 1.11.1.1 C NADH oxidase
CMHHHLFP_00929 3.9e-62 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
CMHHHLFP_00930 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
CMHHHLFP_00931 1.5e-115 ylbE GM NAD(P)H-binding
CMHHHLFP_00932 1.7e-57 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
CMHHHLFP_00933 2.4e-65 S ASCH domain
CMHHHLFP_00934 1.1e-118 S GyrI-like small molecule binding domain
CMHHHLFP_00936 3.4e-160 K Bacterial regulatory helix-turn-helix protein, lysR family
CMHHHLFP_00937 0.0 1.3.5.4 C FMN_bind
CMHHHLFP_00940 2e-208 2.7.7.65 T GGDEF domain
CMHHHLFP_00941 1e-130 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
CMHHHLFP_00942 3.6e-143 T EAL domain
CMHHHLFP_00943 1.5e-244 pgaC GT2 M Glycosyl transferase
CMHHHLFP_00944 1e-90
CMHHHLFP_00945 5.7e-177 C Oxidoreductase
CMHHHLFP_00946 8.1e-09 L Probable transposase
CMHHHLFP_00947 9.3e-214 L TIGRFAM transposase, IS605 OrfB family
CMHHHLFP_00948 6e-27 C pentaerythritol trinitrate reductase activity
CMHHHLFP_00949 4e-109 pncA Q Isochorismatase family
CMHHHLFP_00950 2.9e-13
CMHHHLFP_00951 1.1e-278 yjeM E Amino Acid
CMHHHLFP_00952 2.4e-127 S Alpha beta hydrolase
CMHHHLFP_00954 2.4e-128
CMHHHLFP_00955 9e-127 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
CMHHHLFP_00956 9.2e-71 O OsmC-like protein
CMHHHLFP_00957 1.8e-212 EGP Major facilitator Superfamily
CMHHHLFP_00958 1.2e-233 sptS 2.7.13.3 T Histidine kinase
CMHHHLFP_00959 1.5e-118 K response regulator
CMHHHLFP_00960 1.7e-113 2.7.6.5 T Region found in RelA / SpoT proteins
CMHHHLFP_00961 2.3e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
CMHHHLFP_00962 1.2e-103 dhaL 2.7.1.121 S Dak2
CMHHHLFP_00963 2.1e-61 dhaM 2.7.1.121 S PTS system fructose IIA component
CMHHHLFP_00964 5.6e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CMHHHLFP_00965 1.6e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
CMHHHLFP_00966 0.0 rafA 3.2.1.22 G alpha-galactosidase
CMHHHLFP_00967 2.3e-209 msmX P Belongs to the ABC transporter superfamily
CMHHHLFP_00968 1.5e-152 msmG P Binding-protein-dependent transport system inner membrane component
CMHHHLFP_00969 1.8e-156 msmF P Binding-protein-dependent transport system inner membrane component
CMHHHLFP_00970 4e-242 msmE G Bacterial extracellular solute-binding protein
CMHHHLFP_00971 3.7e-159 msmR K helix_turn_helix, arabinose operon control protein
CMHHHLFP_00972 5e-75 merR K MerR HTH family regulatory protein
CMHHHLFP_00973 1.6e-266 lmrB EGP Major facilitator Superfamily
CMHHHLFP_00974 1.1e-96 S Domain of unknown function (DUF4811)
CMHHHLFP_00975 5.3e-52 S Domain of unknown function (DUF4160)
CMHHHLFP_00976 1.2e-45
CMHHHLFP_00978 1.1e-39 C FMN binding
CMHHHLFP_00979 1.8e-167 S SLAP domain
CMHHHLFP_00980 3.2e-194 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CMHHHLFP_00981 4.3e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CMHHHLFP_00982 2.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CMHHHLFP_00983 2.3e-187 M domain protein
CMHHHLFP_00984 8.8e-113
CMHHHLFP_00985 0.0 lacZ 3.2.1.23 G -beta-galactosidase
CMHHHLFP_00986 0.0 lacS G Transporter
CMHHHLFP_00987 1e-273 E amino acid
CMHHHLFP_00988 1.8e-153 xth 3.1.11.2 L exodeoxyribonuclease III
CMHHHLFP_00989 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMHHHLFP_00990 2.7e-134 S endonuclease exonuclease phosphatase family protein
CMHHHLFP_00991 6.5e-30 S endonuclease exonuclease phosphatase family protein
CMHHHLFP_00992 1.3e-151 3.1.3.102, 3.1.3.104 S hydrolase
CMHHHLFP_00993 0.0 tetP J elongation factor G
CMHHHLFP_00994 4e-138 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CMHHHLFP_00995 1.5e-178 ABC-SBP S ABC transporter
CMHHHLFP_00996 2.6e-126 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
CMHHHLFP_00997 2.6e-135 XK27_08845 S ABC transporter, ATP-binding protein
CMHHHLFP_00998 1.2e-188 lacR K Transcriptional regulator
CMHHHLFP_00999 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
CMHHHLFP_01000 4.3e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
CMHHHLFP_01001 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CMHHHLFP_01002 4.7e-309 2.7.7.7 S Domain of unknown function (DUF5060)
CMHHHLFP_01003 1.3e-216 uhpT EGP Major facilitator Superfamily
CMHHHLFP_01004 2.1e-174 rbsR K helix_turn _helix lactose operon repressor
CMHHHLFP_01005 0.0 3.2.1.40 G Alpha-L-rhamnosidase N-terminal domain
CMHHHLFP_01006 8.1e-60 G polysaccharide catabolic process
CMHHHLFP_01007 1e-78 G YdjC-like protein
CMHHHLFP_01008 7.3e-177 I alpha/beta hydrolase fold
CMHHHLFP_01009 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMHHHLFP_01010 5.7e-155 licT K CAT RNA binding domain
CMHHHLFP_01011 2.4e-258 G Protein of unknown function (DUF4038)
CMHHHLFP_01012 5.7e-175 rbsB G Periplasmic binding protein domain
CMHHHLFP_01013 2e-147 rbsC U Belongs to the binding-protein-dependent transport system permease family
CMHHHLFP_01015 2.7e-277 rbsA 3.6.3.17 G ABC transporter
CMHHHLFP_01016 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CMHHHLFP_01017 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMHHHLFP_01018 1.7e-289 G isomerase
CMHHHLFP_01019 1.6e-210 msmX P Belongs to the ABC transporter superfamily
CMHHHLFP_01020 5.9e-214 malE G Bacterial extracellular solute-binding protein
CMHHHLFP_01021 7.9e-252 malF P Binding-protein-dependent transport system inner membrane component
CMHHHLFP_01022 1.4e-148 malG P ABC transporter permease
CMHHHLFP_01023 6.7e-84
CMHHHLFP_01024 1.6e-146 K Helix-turn-helix XRE-family like proteins
CMHHHLFP_01026 3.7e-07
CMHHHLFP_01027 0.0 nisT V ABC transporter
CMHHHLFP_01028 1.2e-91 ymdB S Macro domain protein
CMHHHLFP_01029 6e-213 I transferase activity, transferring acyl groups other than amino-acyl groups
CMHHHLFP_01031 2.9e-114 mdtG EGP Major facilitator Superfamily
CMHHHLFP_01032 1.5e-49 mdtG EGP Major Facilitator Superfamily
CMHHHLFP_01033 1.1e-233 XK27_04775 S PAS domain
CMHHHLFP_01034 6.5e-99 S Iron-sulfur cluster assembly protein
CMHHHLFP_01035 8.1e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMHHHLFP_01036 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CMHHHLFP_01037 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
CMHHHLFP_01038 0.0 asnB 6.3.5.4 E Asparagine synthase
CMHHHLFP_01039 3.4e-274 S Calcineurin-like phosphoesterase
CMHHHLFP_01040 1.5e-83
CMHHHLFP_01041 8.6e-107 tag 3.2.2.20 L glycosylase
CMHHHLFP_01042 7.6e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
CMHHHLFP_01043 1.3e-56 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
CMHHHLFP_01044 1.1e-123 rfbP M Bacterial sugar transferase
CMHHHLFP_01045 3.6e-148 ywqE 3.1.3.48 GM PHP domain protein
CMHHHLFP_01046 1.5e-125 ywqD 2.7.10.1 D Capsular exopolysaccharide family
CMHHHLFP_01047 1.6e-141 epsB M biosynthesis protein
CMHHHLFP_01048 4e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMHHHLFP_01049 4e-205 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMHHHLFP_01050 3.2e-189 S Cysteine-rich secretory protein family
CMHHHLFP_01051 0.0 2.7.13.3 M Mycoplasma protein of unknown function, DUF285
CMHHHLFP_01052 6.6e-45
CMHHHLFP_01053 3.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CMHHHLFP_01054 1.1e-52
CMHHHLFP_01056 0.0 V Type II restriction enzyme, methylase subunits
CMHHHLFP_01057 6.9e-65 S YjcQ protein
CMHHHLFP_01058 1.7e-13
CMHHHLFP_01059 2.8e-11
CMHHHLFP_01060 2.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
CMHHHLFP_01061 2.5e-118 3.1.3.102, 3.1.3.104, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CMHHHLFP_01062 5.8e-111 S membrane transporter protein
CMHHHLFP_01079 7.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
CMHHHLFP_01080 0.0 L Helicase C-terminal domain protein
CMHHHLFP_01081 1.6e-45 L Helicase C-terminal domain protein
CMHHHLFP_01093 2.3e-223 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
CMHHHLFP_01094 2.9e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
CMHHHLFP_01095 4.7e-180 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMHHHLFP_01096 7.4e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMHHHLFP_01097 3.9e-248 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMHHHLFP_01098 2e-177 pbpX2 V Beta-lactamase
CMHHHLFP_01099 2.7e-61
CMHHHLFP_01100 4.4e-126 S Protein of unknown function (DUF975)
CMHHHLFP_01101 4.3e-167 lysA2 M Glycosyl hydrolases family 25
CMHHHLFP_01102 7.4e-289 ytgP S Polysaccharide biosynthesis protein
CMHHHLFP_01103 9.6e-36
CMHHHLFP_01104 0.0 XK27_06780 V ABC transporter permease
CMHHHLFP_01105 2.5e-166 glfT1 1.1.1.133 S Glycosyltransferase like family 2
CMHHHLFP_01106 4.9e-24 M transferase activity, transferring glycosyl groups
CMHHHLFP_01107 1.4e-121 M transferase activity, transferring glycosyl groups
CMHHHLFP_01108 1.2e-188 M Glycosyltransferase like family 2
CMHHHLFP_01109 4.2e-218 S Psort location CytoplasmicMembrane, score 9.99
CMHHHLFP_01110 9.1e-71 glf 5.4.99.9 M Flavin containing amine oxidoreductase
CMHHHLFP_01111 4.8e-96 glf 5.4.99.9 M UDP-galactopyranose mutase
CMHHHLFP_01112 4.6e-266 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
CMHHHLFP_01113 5.2e-234 L COG3547 Transposase and inactivated derivatives
CMHHHLFP_01114 1e-136 L transposase activity
CMHHHLFP_01115 2.3e-63 L PFAM Integrase catalytic region
CMHHHLFP_01116 3.8e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMHHHLFP_01117 0.0 smc D Required for chromosome condensation and partitioning
CMHHHLFP_01118 2.1e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMHHHLFP_01119 2.5e-288 pipD E Dipeptidase
CMHHHLFP_01120 2.8e-67
CMHHHLFP_01121 3.2e-259 yfnA E amino acid
CMHHHLFP_01122 1.6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CMHHHLFP_01123 2.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMHHHLFP_01124 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CMHHHLFP_01125 4.7e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMHHHLFP_01126 5e-128 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CMHHHLFP_01127 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMHHHLFP_01128 3.7e-70 2.4.1.83 GT2 S GtrA-like protein
CMHHHLFP_01129 0.0 S Bacterial membrane protein, YfhO
CMHHHLFP_01130 3.4e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
CMHHHLFP_01131 3.7e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
CMHHHLFP_01132 3.1e-144 E GDSL-like Lipase/Acylhydrolase family
CMHHHLFP_01133 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMHHHLFP_01134 1.1e-37 ynzC S UPF0291 protein
CMHHHLFP_01135 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
CMHHHLFP_01136 0.0 mdlA V ABC transporter
CMHHHLFP_01137 3.6e-292 mdlB V ABC transporter
CMHHHLFP_01138 0.0 pepO 3.4.24.71 O Peptidase family M13
CMHHHLFP_01139 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CMHHHLFP_01140 6.4e-116 plsC 2.3.1.51 I Acyltransferase
CMHHHLFP_01141 1.3e-198 yabB 2.1.1.223 L Methyltransferase small domain
CMHHHLFP_01142 1.1e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
CMHHHLFP_01143 2.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMHHHLFP_01144 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CMHHHLFP_01145 8.7e-88 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CMHHHLFP_01146 9.3e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMHHHLFP_01147 1.7e-145 cdsA 2.7.7.41 I Belongs to the CDS family
CMHHHLFP_01148 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CMHHHLFP_01149 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMHHHLFP_01150 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMHHHLFP_01151 7.2e-83 rimP J Required for maturation of 30S ribosomal subunits
CMHHHLFP_01152 3.3e-198 nusA K Participates in both transcription termination and antitermination
CMHHHLFP_01153 1.4e-47 ylxR K Protein of unknown function (DUF448)
CMHHHLFP_01154 8.4e-48 rplGA J ribosomal protein
CMHHHLFP_01155 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMHHHLFP_01156 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMHHHLFP_01157 1e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMHHHLFP_01158 5.2e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CMHHHLFP_01159 2.5e-283 lsa S ABC transporter
CMHHHLFP_01160 1.7e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMHHHLFP_01161 1.9e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMHHHLFP_01162 0.0 dnaK O Heat shock 70 kDa protein
CMHHHLFP_01163 7.8e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMHHHLFP_01164 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMHHHLFP_01165 4.8e-120 srtA 3.4.22.70 M sortase family
CMHHHLFP_01166 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CMHHHLFP_01167 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMHHHLFP_01168 2.9e-78 K Acetyltransferase (GNAT) domain
CMHHHLFP_01170 4.7e-151 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CMHHHLFP_01171 1.1e-211 S Bacterial protein of unknown function (DUF871)
CMHHHLFP_01172 1.6e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMHHHLFP_01173 4.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CMHHHLFP_01174 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMHHHLFP_01175 1.8e-87 3.4.21.96 S SLAP domain
CMHHHLFP_01176 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
CMHHHLFP_01177 1.5e-155 lysR5 K LysR substrate binding domain
CMHHHLFP_01178 4.8e-99 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CMHHHLFP_01179 4.8e-229 S Sterol carrier protein domain
CMHHHLFP_01180 3.7e-15
CMHHHLFP_01181 2.2e-108 K LysR substrate binding domain
CMHHHLFP_01182 1.3e-99
CMHHHLFP_01183 1.1e-121 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
CMHHHLFP_01184 1.3e-295
CMHHHLFP_01185 6.4e-201 brnQ U Component of the transport system for branched-chain amino acids
CMHHHLFP_01186 4.5e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
CMHHHLFP_01187 2e-10
CMHHHLFP_01188 0.0
CMHHHLFP_01189 2.8e-103 lacA 2.3.1.79 S Transferase hexapeptide repeat
CMHHHLFP_01190 1.1e-18 yjgN S Bacterial protein of unknown function (DUF898)
CMHHHLFP_01191 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
CMHHHLFP_01192 9.4e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
CMHHHLFP_01193 6.4e-287 thrC 4.2.3.1 E Threonine synthase
CMHHHLFP_01194 1.3e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CMHHHLFP_01195 4.8e-162 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMHHHLFP_01196 4.8e-122
CMHHHLFP_01197 2.2e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMHHHLFP_01198 2.8e-110 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMHHHLFP_01199 1.3e-95 S Peptidase family M23
CMHHHLFP_01200 4e-153 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CMHHHLFP_01201 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CMHHHLFP_01202 6.5e-70 yqeY S YqeY-like protein
CMHHHLFP_01203 1.3e-176 phoH T phosphate starvation-inducible protein PhoH
CMHHHLFP_01204 7.9e-99 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMHHHLFP_01205 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMHHHLFP_01206 1.7e-134 recO L Involved in DNA repair and RecF pathway recombination
CMHHHLFP_01207 2.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CMHHHLFP_01208 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CMHHHLFP_01209 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMHHHLFP_01210 1.4e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMHHHLFP_01211 1.1e-126 S Peptidase family M23
CMHHHLFP_01212 5.6e-82 mutT 3.6.1.55 F NUDIX domain
CMHHHLFP_01213 1.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
CMHHHLFP_01214 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMHHHLFP_01215 1.3e-245 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CMHHHLFP_01216 8e-61 yvoA_1 K Transcriptional regulator, GntR family
CMHHHLFP_01217 1.1e-122 skfE V ATPases associated with a variety of cellular activities
CMHHHLFP_01218 3.9e-132
CMHHHLFP_01219 4e-145
CMHHHLFP_01220 6.8e-131
CMHHHLFP_01221 2.2e-27
CMHHHLFP_01222 8.9e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CMHHHLFP_01223 4.1e-141
CMHHHLFP_01224 3.8e-179
CMHHHLFP_01225 1.1e-267 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
CMHHHLFP_01226 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
CMHHHLFP_01227 4.4e-55 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
CMHHHLFP_01228 1.3e-107 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
CMHHHLFP_01229 5.2e-145 K SIS domain
CMHHHLFP_01230 4.2e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CMHHHLFP_01231 8.4e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CMHHHLFP_01232 4.1e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CMHHHLFP_01233 6.6e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
CMHHHLFP_01234 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CMHHHLFP_01235 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CMHHHLFP_01236 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CMHHHLFP_01237 1.4e-89 ypmB S Protein conserved in bacteria
CMHHHLFP_01238 2.4e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
CMHHHLFP_01239 5.7e-115 dnaD L DnaD domain protein
CMHHHLFP_01240 1.5e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMHHHLFP_01241 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
CMHHHLFP_01242 7.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMHHHLFP_01243 9.4e-106 ypsA S Belongs to the UPF0398 family
CMHHHLFP_01244 1.7e-52
CMHHHLFP_01245 7.6e-247 G Major Facilitator
CMHHHLFP_01246 5.5e-15
CMHHHLFP_01247 3.6e-105 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
CMHHHLFP_01248 7.1e-176 K AI-2E family transporter
CMHHHLFP_01249 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
CMHHHLFP_01250 5.9e-54 S Domain of unknown function (DUF4430)
CMHHHLFP_01251 4.5e-86 S ECF transporter, substrate-specific component
CMHHHLFP_01252 7.7e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
CMHHHLFP_01253 3.6e-151 S Putative ABC-transporter type IV
CMHHHLFP_01254 1.2e-95 S LPXTG cell wall anchor motif
CMHHHLFP_01255 1.8e-127 T Transcriptional regulatory protein, C terminal
CMHHHLFP_01256 1.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
CMHHHLFP_01257 4.8e-296 V ABC transporter transmembrane region
CMHHHLFP_01258 1.5e-143 S PAS domain
CMHHHLFP_01259 3.5e-48
CMHHHLFP_01260 6.2e-264
CMHHHLFP_01261 4.5e-140 pnuC H nicotinamide mononucleotide transporter
CMHHHLFP_01262 9.6e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
CMHHHLFP_01263 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
CMHHHLFP_01264 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
CMHHHLFP_01265 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
CMHHHLFP_01266 9.4e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMHHHLFP_01267 4.8e-179 yvdE K helix_turn _helix lactose operon repressor
CMHHHLFP_01268 3.2e-21 ptp2 3.1.3.48 T Tyrosine phosphatase family
CMHHHLFP_01269 9.9e-258 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMHHHLFP_01270 2.7e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMHHHLFP_01271 4.6e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMHHHLFP_01272 1.1e-47 yajC U Preprotein translocase
CMHHHLFP_01273 5.3e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMHHHLFP_01274 2.2e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMHHHLFP_01275 6.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
CMHHHLFP_01276 3.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CMHHHLFP_01277 8.7e-11 S Putative adhesin
CMHHHLFP_01278 5e-194 napA P Sodium/hydrogen exchanger family
CMHHHLFP_01279 0.0 cadA P P-type ATPase
CMHHHLFP_01280 2.1e-82 ykuL S (CBS) domain
CMHHHLFP_01281 9.1e-217 ywhK S Membrane
CMHHHLFP_01282 3.6e-40
CMHHHLFP_01283 7.6e-18 S D-Ala-teichoic acid biosynthesis protein
CMHHHLFP_01284 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMHHHLFP_01285 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMHHHLFP_01286 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMHHHLFP_01287 3.6e-186 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMHHHLFP_01288 6.9e-11
CMHHHLFP_01289 1.9e-69
CMHHHLFP_01290 0.0 kup P Transport of potassium into the cell
CMHHHLFP_01291 0.0 pepO 3.4.24.71 O Peptidase family M13
CMHHHLFP_01292 6.8e-170 yttB EGP Major facilitator Superfamily
CMHHHLFP_01293 3.7e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CMHHHLFP_01294 1.8e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CMHHHLFP_01295 3.9e-75 atkY K Penicillinase repressor
CMHHHLFP_01296 3.8e-309 E ABC transporter, substratebinding protein
CMHHHLFP_01297 1.2e-23
CMHHHLFP_01298 3.4e-223 pbuG S permease
CMHHHLFP_01299 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
CMHHHLFP_01300 2.3e-95 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
CMHHHLFP_01301 2e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CMHHHLFP_01302 3.7e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMHHHLFP_01303 1.1e-34 S Protein of unknown function (DUF2508)
CMHHHLFP_01304 2.3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMHHHLFP_01305 5.8e-52 yaaQ S Cyclic-di-AMP receptor
CMHHHLFP_01306 2.6e-155 holB 2.7.7.7 L DNA polymerase III
CMHHHLFP_01307 3e-60 yabA L Involved in initiation control of chromosome replication
CMHHHLFP_01308 6.7e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMHHHLFP_01309 9.6e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
CMHHHLFP_01310 5.2e-87 S ECF transporter, substrate-specific component
CMHHHLFP_01311 1.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
CMHHHLFP_01312 3.3e-106 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
CMHHHLFP_01313 1.1e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMHHHLFP_01314 3.9e-173 K helix_turn_helix, arabinose operon control protein
CMHHHLFP_01315 1.6e-163 htpX O Belongs to the peptidase M48B family
CMHHHLFP_01316 1.4e-93 lemA S LemA family
CMHHHLFP_01317 2.5e-195 ybiR P Citrate transporter
CMHHHLFP_01318 2.2e-69 S Iron-sulphur cluster biosynthesis
CMHHHLFP_01319 1.1e-301 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
CMHHHLFP_01320 1.2e-17
CMHHHLFP_01325 2.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMHHHLFP_01326 2.9e-260 qacA EGP Major facilitator Superfamily
CMHHHLFP_01327 1.5e-30 cydA 1.10.3.14 C ubiquinol oxidase
CMHHHLFP_01328 2.3e-116 ndh 1.6.99.3 C NADH dehydrogenase
CMHHHLFP_01329 4.4e-91 ndh 1.6.99.3 C NADH dehydrogenase
CMHHHLFP_01330 3.9e-119 3.6.1.27 I Acid phosphatase homologues
CMHHHLFP_01331 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMHHHLFP_01332 2.2e-296 ytgP S Polysaccharide biosynthesis protein
CMHHHLFP_01333 4.8e-16
CMHHHLFP_01334 5.5e-71 K transcriptional regulator
CMHHHLFP_01335 2.8e-17 K transcriptional regulator
CMHHHLFP_01336 0.0 sprD D Domain of Unknown Function (DUF1542)
CMHHHLFP_01337 3.8e-80 yphH S Cupin domain
CMHHHLFP_01338 0.0 S domain, Protein
CMHHHLFP_01339 9.1e-40 S Enterocin A Immunity
CMHHHLFP_01340 7e-258 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
CMHHHLFP_01341 3e-54 yvlA
CMHHHLFP_01342 5.5e-197 V Beta-lactamase
CMHHHLFP_01343 6.4e-54 pspC KT PspC domain
CMHHHLFP_01345 1.7e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CMHHHLFP_01346 8.1e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMHHHLFP_01347 6.9e-127 M ErfK YbiS YcfS YnhG
CMHHHLFP_01348 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CMHHHLFP_01349 2.7e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
CMHHHLFP_01350 4.1e-192 5.3.3.2 C FMN-dependent dehydrogenase
CMHHHLFP_01351 6.8e-119
CMHHHLFP_01352 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CMHHHLFP_01353 2.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMHHHLFP_01354 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CMHHHLFP_01355 6.8e-54 yheA S Belongs to the UPF0342 family
CMHHHLFP_01356 2.4e-231 yhaO L Ser Thr phosphatase family protein
CMHHHLFP_01357 0.0 L AAA domain
CMHHHLFP_01358 8.4e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMHHHLFP_01359 1.1e-148 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMHHHLFP_01360 1.4e-56
CMHHHLFP_01361 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
CMHHHLFP_01362 2e-135 ecsA V ABC transporter, ATP-binding protein
CMHHHLFP_01363 7.4e-201 ecsB U ABC transporter
CMHHHLFP_01364 1.5e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMHHHLFP_01365 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CMHHHLFP_01366 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMHHHLFP_01367 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CMHHHLFP_01368 0.0
CMHHHLFP_01369 1.7e-148 ybbH K Helix-turn-helix domain, rpiR family
CMHHHLFP_01370 1.2e-29 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CMHHHLFP_01371 5.5e-295 G phosphotransferase system
CMHHHLFP_01372 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMHHHLFP_01373 1.8e-92 S Membrane
CMHHHLFP_01374 6.6e-167 rocF 3.5.3.1, 3.5.3.11 E Arginase family
CMHHHLFP_01375 2.9e-238 mepA V MATE efflux family protein
CMHHHLFP_01376 1.2e-97 L Putative transposase DNA-binding domain
CMHHHLFP_01377 1.9e-112 L Putative transposase DNA-binding domain
CMHHHLFP_01378 3.2e-178 S SLAP domain
CMHHHLFP_01379 6.7e-292 M Peptidase family M1 domain
CMHHHLFP_01380 2.4e-194 S Bacteriocin helveticin-J
CMHHHLFP_01381 1.1e-50 L RelB antitoxin
CMHHHLFP_01382 9.7e-142 qmcA O prohibitin homologues
CMHHHLFP_01383 1.1e-124 darA C Flavodoxin
CMHHHLFP_01384 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CMHHHLFP_01385 9.6e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMHHHLFP_01386 3.6e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMHHHLFP_01387 2.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CMHHHLFP_01388 7.6e-39 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMHHHLFP_01389 6.1e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMHHHLFP_01390 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMHHHLFP_01391 1.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMHHHLFP_01392 2e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CMHHHLFP_01393 2.7e-111 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMHHHLFP_01394 5e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CMHHHLFP_01395 5.3e-250 purD 6.3.4.13 F Belongs to the GARS family
CMHHHLFP_01396 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMHHHLFP_01397 4.8e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CMHHHLFP_01398 6.9e-107 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMHHHLFP_01399 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMHHHLFP_01400 1.7e-251 dnaB L Replication initiation and membrane attachment
CMHHHLFP_01401 6.9e-167 dnaI L Primosomal protein DnaI
CMHHHLFP_01402 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMHHHLFP_01403 5.6e-74 K LytTr DNA-binding domain
CMHHHLFP_01404 5.7e-71 S Protein of unknown function (DUF3021)
CMHHHLFP_01405 3.2e-92
CMHHHLFP_01406 2.9e-73 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMHHHLFP_01407 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CMHHHLFP_01408 1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMHHHLFP_01409 3.5e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CMHHHLFP_01410 1.9e-198 tnpB L Putative transposase DNA-binding domain
CMHHHLFP_01411 1.6e-93 yqeG S HAD phosphatase, family IIIA
CMHHHLFP_01412 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
CMHHHLFP_01413 5.2e-124 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMHHHLFP_01414 1.4e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
CMHHHLFP_01415 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMHHHLFP_01416 2.7e-216 ylbM S Belongs to the UPF0348 family
CMHHHLFP_01417 2.4e-98 yceD S Uncharacterized ACR, COG1399
CMHHHLFP_01418 2.5e-127 K response regulator
CMHHHLFP_01419 1.9e-249 arlS 2.7.13.3 T Histidine kinase
CMHHHLFP_01420 4.3e-159 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMHHHLFP_01421 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CMHHHLFP_01422 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMHHHLFP_01423 4.7e-63 yodB K Transcriptional regulator, HxlR family
CMHHHLFP_01424 1.2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMHHHLFP_01425 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMHHHLFP_01426 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMHHHLFP_01427 6.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
CMHHHLFP_01428 3.6e-254 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CMHHHLFP_01429 1.1e-12 ltrA S Bacterial low temperature requirement A protein (LtrA)
CMHHHLFP_01430 1.7e-35 ltrA S Bacterial low temperature requirement A protein (LtrA)
CMHHHLFP_01431 0.0 O Belongs to the peptidase S8 family
CMHHHLFP_01432 2.3e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
CMHHHLFP_01433 0.0 S membrane
CMHHHLFP_01434 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
CMHHHLFP_01435 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CMHHHLFP_01436 1.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CMHHHLFP_01437 1.2e-118 gluP 3.4.21.105 S Rhomboid family
CMHHHLFP_01438 1.6e-32 yqgQ S Bacterial protein of unknown function (DUF910)
CMHHHLFP_01439 1.1e-149 vicX 3.1.26.11 S domain protein
CMHHHLFP_01440 9.4e-147 yycI S YycH protein
CMHHHLFP_01441 1e-259 yycH S YycH protein
CMHHHLFP_01442 5.3e-307 vicK 2.7.13.3 T Histidine kinase
CMHHHLFP_01443 9.7e-132 K response regulator
CMHHHLFP_01445 1.6e-58 cadX K helix_turn_helix, Arsenical Resistance Operon Repressor
CMHHHLFP_01446 5e-184
CMHHHLFP_01447 4.6e-54
CMHHHLFP_01448 1.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CMHHHLFP_01449 8.6e-93
CMHHHLFP_01450 4.9e-184 repB EP Plasmid replication protein
CMHHHLFP_01451 1.5e-31
CMHHHLFP_01452 4e-234 L Belongs to the 'phage' integrase family
CMHHHLFP_01453 8e-142 puuD S peptidase C26
CMHHHLFP_01454 1.7e-241 steT_1 E amino acid
CMHHHLFP_01455 1.1e-52 yusE CO Thioredoxin
CMHHHLFP_01457 3.6e-117 M1-798 K Rhodanese Homology Domain
CMHHHLFP_01458 1.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMHHHLFP_01459 1.1e-118 frnE Q DSBA-like thioredoxin domain
CMHHHLFP_01460 3e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
CMHHHLFP_01461 1.5e-223 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMHHHLFP_01462 0.0 pepF E oligoendopeptidase F
CMHHHLFP_01463 6.7e-44 P transmembrane transport
CMHHHLFP_01464 7e-265 lctP C L-lactate permease
CMHHHLFP_01465 2.9e-51
CMHHHLFP_01466 8.3e-148 K Helix-turn-helix XRE-family like proteins
CMHHHLFP_01467 5.6e-126 S Alpha/beta hydrolase family
CMHHHLFP_01468 7.3e-160 2.4.1.293 GT2 M Glycosyltransferase like family 2
CMHHHLFP_01469 7.7e-137 ypuA S Protein of unknown function (DUF1002)
CMHHHLFP_01470 2.2e-142 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMHHHLFP_01471 3.4e-163 dam2 2.1.1.72 L DNA methyltransferase
CMHHHLFP_01472 7.1e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
CMHHHLFP_01474 6.3e-57
CMHHHLFP_01475 1.9e-211 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CMHHHLFP_01477 2.1e-86 S Peptidase propeptide and YPEB domain
CMHHHLFP_01478 2.3e-97 S Peptidase propeptide and YPEB domain
CMHHHLFP_01479 2.8e-76 yybA 2.3.1.57 K Transcriptional regulator
CMHHHLFP_01480 6.8e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
CMHHHLFP_01481 0.0 E ABC transporter, substratebinding protein
CMHHHLFP_01482 1.1e-54 ypaA S Protein of unknown function (DUF1304)
CMHHHLFP_01483 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMHHHLFP_01484 2.4e-150 K Helix-turn-helix XRE-family like proteins
CMHHHLFP_01486 2.1e-258 S CAAX protease self-immunity
CMHHHLFP_01487 4.5e-18
CMHHHLFP_01488 2.3e-278 pipD E Dipeptidase
CMHHHLFP_01489 3.9e-161 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
CMHHHLFP_01492 5.3e-20 S Protein of unknown function (DUF3923)
CMHHHLFP_01493 6.5e-69 doc S Fic/DOC family
CMHHHLFP_01494 7.4e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CMHHHLFP_01495 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CMHHHLFP_01496 7.5e-25 secG U Preprotein translocase
CMHHHLFP_01497 1.2e-182 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMHHHLFP_01498 3.3e-135 gntR K UbiC transcription regulator-associated domain protein
CMHHHLFP_01499 6.3e-176 rihB 3.2.2.1 F Nucleoside
CMHHHLFP_01500 0.0 kup P Transport of potassium into the cell
CMHHHLFP_01501 2e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMHHHLFP_01502 5.9e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMHHHLFP_01503 4.1e-163 2.7.7.12 C Domain of unknown function (DUF4931)
CMHHHLFP_01504 4.8e-238 G Bacterial extracellular solute-binding protein
CMHHHLFP_01505 1.2e-63
CMHHHLFP_01506 1.5e-174 S Protein of unknown function (DUF2974)
CMHHHLFP_01507 1.9e-110 glnP P ABC transporter permease
CMHHHLFP_01508 6.1e-93 gluC P ABC transporter permease
CMHHHLFP_01509 1.3e-148 glnH ET ABC transporter substrate-binding protein
CMHHHLFP_01510 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMHHHLFP_01511 7.2e-115 udk 2.7.1.48 F Zeta toxin
CMHHHLFP_01512 2.9e-102 S ABC-type cobalt transport system, permease component
CMHHHLFP_01513 0.0 V ABC transporter transmembrane region
CMHHHLFP_01514 1.1e-306 XK27_09600 V ABC transporter, ATP-binding protein
CMHHHLFP_01515 2.3e-78 K Transcriptional regulator, MarR family
CMHHHLFP_01516 9e-150 glnH ET ABC transporter
CMHHHLFP_01517 9.8e-146
CMHHHLFP_01518 0.0 ybiT S ABC transporter, ATP-binding protein
CMHHHLFP_01519 2.1e-210 pepA E M42 glutamyl aminopeptidase
CMHHHLFP_01520 1.8e-165 mleP3 S Membrane transport protein
CMHHHLFP_01521 4e-215 mdtG EGP Major facilitator Superfamily
CMHHHLFP_01522 1.6e-253 emrY EGP Major facilitator Superfamily
CMHHHLFP_01523 2.4e-50 3.1.3.102, 3.1.3.104 Q phosphatase activity
CMHHHLFP_01524 1.5e-86 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CMHHHLFP_01525 9.5e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMHHHLFP_01526 2.1e-241 pyrP F Permease
CMHHHLFP_01527 5.1e-128 cydD V cysteine transport
CMHHHLFP_01528 3.6e-109 V ABC-type multidrug transport system, ATPase and permease components
CMHHHLFP_01529 8e-162 S reductase
CMHHHLFP_01530 8.4e-78 2.3.1.128 K acetyltransferase
CMHHHLFP_01531 0.0 4.2.1.53 S Myosin-crossreactive antigen
CMHHHLFP_01532 5e-90 yxdD K Bacterial regulatory proteins, tetR family
CMHHHLFP_01533 6.8e-136 S CAAX protease self-immunity
CMHHHLFP_01534 3.9e-244 emrY EGP Major facilitator Superfamily
CMHHHLFP_01539 6.6e-95 MA20_25245 K Acetyltransferase (GNAT) domain
CMHHHLFP_01540 1.4e-178 L Recombinase zinc beta ribbon domain
CMHHHLFP_01541 7.8e-94 L Resolvase, N terminal domain
CMHHHLFP_01542 9e-192 L Recombinase
CMHHHLFP_01543 6.5e-57 5.1.1.13 M Asp/Glu/Hydantoin racemase
CMHHHLFP_01544 1.2e-48 5.1.1.13 M Asp/Glu/Hydantoin racemase
CMHHHLFP_01545 2.8e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
CMHHHLFP_01546 8.1e-114 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
CMHHHLFP_01547 5e-96 dps P Belongs to the Dps family
CMHHHLFP_01548 3.9e-34 copZ C Heavy-metal-associated domain
CMHHHLFP_01549 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
CMHHHLFP_01550 1.1e-62
CMHHHLFP_01551 1.6e-22
CMHHHLFP_01552 9.6e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMHHHLFP_01553 1.5e-245 nhaC C Na H antiporter NhaC
CMHHHLFP_01554 4.1e-56
CMHHHLFP_01555 6.6e-106 ybhL S Belongs to the BI1 family
CMHHHLFP_01556 4.2e-172 yegS 2.7.1.107 G Lipid kinase
CMHHHLFP_01557 1.9e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMHHHLFP_01558 1.5e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMHHHLFP_01559 2.6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMHHHLFP_01560 1.1e-201 camS S sex pheromone
CMHHHLFP_01561 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMHHHLFP_01562 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CMHHHLFP_01563 2.8e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
CMHHHLFP_01565 4.3e-64 ydcK S Belongs to the SprT family
CMHHHLFP_01566 9.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
CMHHHLFP_01567 1.1e-256 epsU S Polysaccharide biosynthesis protein
CMHHHLFP_01568 2.9e-226 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMHHHLFP_01569 0.0 pacL 3.6.3.8 P P-type ATPase
CMHHHLFP_01570 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CMHHHLFP_01571 1.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMHHHLFP_01572 1.1e-206 csaB M Glycosyl transferases group 1
CMHHHLFP_01573 8e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CMHHHLFP_01574 1.5e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
CMHHHLFP_01575 7.3e-124 gntR1 K UTRA
CMHHHLFP_01576 4e-209
CMHHHLFP_01579 3.9e-276 slpX S SLAP domain
CMHHHLFP_01580 1.3e-177 pfoS S Phosphotransferase system, EIIC
CMHHHLFP_01582 6.1e-70 EGP Major facilitator Superfamily
CMHHHLFP_01583 2.6e-285 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
CMHHHLFP_01584 6.5e-212 msmX P Belongs to the ABC transporter superfamily
CMHHHLFP_01585 5.8e-260 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
CMHHHLFP_01586 3.3e-155 msmG G Binding-protein-dependent transport system inner membrane component
CMHHHLFP_01587 4.5e-163 msmF P ABC-type sugar transport systems, permease components
CMHHHLFP_01588 2.7e-249 G Bacterial extracellular solute-binding protein
CMHHHLFP_01589 3.9e-184 msmR K helix_turn _helix lactose operon repressor
CMHHHLFP_01590 5.4e-52 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CMHHHLFP_01591 1e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
CMHHHLFP_01592 6.6e-107 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
CMHHHLFP_01593 4.9e-110 5.4.2.11 G Phosphoglycerate mutase family
CMHHHLFP_01594 4.1e-195 D nuclear chromosome segregation
CMHHHLFP_01595 7.8e-70 M LysM domain protein
CMHHHLFP_01596 2.5e-161 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CMHHHLFP_01597 2.1e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHHHLFP_01598 5.6e-13
CMHHHLFP_01599 3.1e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
CMHHHLFP_01600 5.9e-67
CMHHHLFP_01601 5.1e-33
CMHHHLFP_01602 1.3e-69 S Iron-sulphur cluster biosynthesis
CMHHHLFP_01603 1.3e-229 L Belongs to the 'phage' integrase family
CMHHHLFP_01604 2.8e-12
CMHHHLFP_01605 3.4e-63 repB EP Plasmid replication protein
CMHHHLFP_01606 7.1e-122
CMHHHLFP_01607 3.2e-205 cycA E Amino acid permease
CMHHHLFP_01608 6.6e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CMHHHLFP_01609 0.0 clpE O AAA domain (Cdc48 subfamily)
CMHHHLFP_01610 1.4e-62 pdxH S Pyridoxamine 5'-phosphate oxidase
CMHHHLFP_01611 7.9e-135 znuB U ABC 3 transport family
CMHHHLFP_01612 1e-116 fhuC P ABC transporter
CMHHHLFP_01613 2.6e-152 psaA P Belongs to the bacterial solute-binding protein 9 family
CMHHHLFP_01614 2.2e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CMHHHLFP_01615 1.4e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHHHLFP_01616 2.6e-67 L Helicase C-terminal domain protein
CMHHHLFP_01617 2.9e-215 pbpX1 V Beta-lactamase
CMHHHLFP_01618 3.2e-71 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CMHHHLFP_01619 5e-227 pbuG S permease
CMHHHLFP_01620 6.8e-295 V ABC transporter transmembrane region
CMHHHLFP_01621 4.3e-286 V ABC transporter transmembrane region
CMHHHLFP_01622 3.4e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CMHHHLFP_01623 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CMHHHLFP_01624 7.2e-244 cpdA S Calcineurin-like phosphoesterase
CMHHHLFP_01625 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CMHHHLFP_01626 3.6e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMHHHLFP_01627 3.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMHHHLFP_01628 3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CMHHHLFP_01629 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
CMHHHLFP_01630 0.0 FbpA K Fibronectin-binding protein
CMHHHLFP_01631 9e-66
CMHHHLFP_01632 6.1e-160 degV S EDD domain protein, DegV family
CMHHHLFP_01633 8.4e-196 xerS L Belongs to the 'phage' integrase family
CMHHHLFP_01634 3.1e-59
CMHHHLFP_01635 1.5e-91 adk 2.7.4.3 F topology modulation protein
CMHHHLFP_01636 2.4e-107 XK27_00160 S Domain of unknown function (DUF5052)
CMHHHLFP_01637 4.3e-200 M Glycosyl hydrolases family 25
CMHHHLFP_01639 3.3e-58 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CMHHHLFP_01640 3.9e-84 K transcriptional
CMHHHLFP_01641 1e-213 EGP Transmembrane secretion effector
CMHHHLFP_01642 2.3e-287 V ABC-type multidrug transport system, ATPase and permease components
CMHHHLFP_01643 1.5e-286 V ABC-type multidrug transport system, ATPase and permease components
CMHHHLFP_01645 8.2e-66 fic D Fic/DOC family
CMHHHLFP_01646 1.1e-127 yoaK S Protein of unknown function (DUF1275)
CMHHHLFP_01647 1.2e-39 K Helix-turn-helix domain
CMHHHLFP_01648 1.7e-113 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMHHHLFP_01649 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
CMHHHLFP_01650 7.8e-185 K Transcriptional regulator
CMHHHLFP_01651 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMHHHLFP_01652 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMHHHLFP_01653 1.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMHHHLFP_01654 7e-101
CMHHHLFP_01655 1.9e-168 MA20_14895 S Conserved hypothetical protein 698
CMHHHLFP_01656 2.2e-18 magIII L Base excision DNA repair protein, HhH-GPD family
CMHHHLFP_01657 9.2e-17 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMHHHLFP_01658 5e-44 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMHHHLFP_01659 1.3e-12 S Alpha beta hydrolase
CMHHHLFP_01660 3e-251 yagE E amino acid
CMHHHLFP_01662 3.3e-77 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
CMHHHLFP_01663 2.6e-149 P FAD-binding domain
CMHHHLFP_01664 2.3e-14 C Flavodoxin
CMHHHLFP_01665 7.8e-97 S LexA-binding, inner membrane-associated putative hydrolase
CMHHHLFP_01666 4.2e-141 fldA C Flavodoxin
CMHHHLFP_01667 4.1e-23
CMHHHLFP_01668 2.4e-261 gor 1.8.1.7 C Glutathione reductase
CMHHHLFP_01669 7.7e-100 P esterase
CMHHHLFP_01670 2.7e-98 fldA C Flavodoxin
CMHHHLFP_01672 1e-20 C Flavodoxin
CMHHHLFP_01673 3.6e-146 glcU U ribose uptake protein RbsU
CMHHHLFP_01674 2.9e-60 C aldo keto reductase
CMHHHLFP_01675 7.2e-115 tas C Aldo/keto reductase family
CMHHHLFP_01676 7.1e-55 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
CMHHHLFP_01677 2.6e-146 IQ reductase
CMHHHLFP_01678 3.1e-83 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
CMHHHLFP_01679 3.5e-174 yobV1 K WYL domain
CMHHHLFP_01680 0.0
CMHHHLFP_01681 0.0
CMHHHLFP_01682 0.0 ppc 4.1.1.31 C phosphoenolpyruvate carboxylase activity
CMHHHLFP_01683 2.2e-148 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMHHHLFP_01684 2.4e-40 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMHHHLFP_01685 4.4e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMHHHLFP_01686 1.8e-240 steT E amino acid
CMHHHLFP_01687 4.3e-115 ywnB S NAD(P)H-binding
CMHHHLFP_01688 3.3e-155 F DNA/RNA non-specific endonuclease
CMHHHLFP_01689 7.9e-67 L nuclease
CMHHHLFP_01690 2.3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMHHHLFP_01691 4.7e-218 2.1.1.14 E methionine synthase, vitamin-B12 independent
CMHHHLFP_01692 7.7e-114 S L,D-transpeptidase catalytic domain
CMHHHLFP_01693 2.9e-195 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMHHHLFP_01694 4.4e-244 yrvN L AAA C-terminal domain
CMHHHLFP_01695 1.9e-101 ltrA S Bacterial low temperature requirement A protein (LtrA)
CMHHHLFP_01696 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
CMHHHLFP_01697 1.8e-167 mleR K LysR family
CMHHHLFP_01698 1.3e-38
CMHHHLFP_01699 1.5e-91
CMHHHLFP_01700 8.3e-53 mleP S Sodium Bile acid symporter family
CMHHHLFP_01701 7.2e-36
CMHHHLFP_01702 1.4e-112 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CMHHHLFP_01703 1.4e-144 2.4.2.3 F Phosphorylase superfamily
CMHHHLFP_01704 5.1e-147 2.4.2.3 F Phosphorylase superfamily
CMHHHLFP_01705 6.2e-108 5.4.2.11 G Phosphoglycerate mutase family
CMHHHLFP_01706 1.5e-146 2.4.2.3 F Phosphorylase superfamily
CMHHHLFP_01707 4.3e-39
CMHHHLFP_01708 1.3e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
CMHHHLFP_01711 3.1e-78 K helix_turn_helix, mercury resistance
CMHHHLFP_01712 9.9e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMHHHLFP_01713 3.5e-171 coaA 2.7.1.33 F Pantothenic acid kinase
CMHHHLFP_01714 6.7e-104 E GDSL-like Lipase/Acylhydrolase
CMHHHLFP_01715 9.9e-82 yjcF S Acetyltransferase (GNAT) domain
CMHHHLFP_01716 2.8e-151 aatB ET ABC transporter substrate-binding protein
CMHHHLFP_01717 9e-110 glnQ 3.6.3.21 E ABC transporter
CMHHHLFP_01718 3e-108 glnP P ABC transporter permease
CMHHHLFP_01719 1.1e-22 helD 3.6.4.12 L DNA helicase
CMHHHLFP_01720 0.0 helD 3.6.4.12 L DNA helicase
CMHHHLFP_01721 9.9e-126 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
CMHHHLFP_01722 8.5e-127 pgm3 5.4.2.11 G Phosphoglycerate mutase family
CMHHHLFP_01723 0.0 V FtsX-like permease family
CMHHHLFP_01724 1.7e-134 cysA V ABC transporter, ATP-binding protein
CMHHHLFP_01725 1.6e-241 S response to antibiotic
CMHHHLFP_01726 1.1e-127
CMHHHLFP_01727 0.0 3.6.3.8 P P-type ATPase
CMHHHLFP_01728 2.1e-64 2.7.1.191 G PTS system fructose IIA component
CMHHHLFP_01729 2.1e-48
CMHHHLFP_01730 1.9e-15
CMHHHLFP_01731 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
CMHHHLFP_01732 1.5e-138 glvR K Helix-turn-helix domain, rpiR family
CMHHHLFP_01733 4.1e-269 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
CMHHHLFP_01734 4.3e-155
CMHHHLFP_01735 3.4e-91
CMHHHLFP_01736 4.2e-106 3.2.2.20 K acetyltransferase
CMHHHLFP_01739 4.4e-311 asdA 4.1.1.12 E Aminotransferase
CMHHHLFP_01740 3.2e-303 aspT P Predicted Permease Membrane Region
CMHHHLFP_01741 4.2e-189 S Domain of unknown function (DUF4767)
CMHHHLFP_01742 2.5e-184 S Membrane
CMHHHLFP_01743 6.4e-150 xth 3.1.11.2 L exodeoxyribonuclease III
CMHHHLFP_01744 7.9e-188 K helix_turn_helix, arabinose operon control protein
CMHHHLFP_01745 7.8e-188 K helix_turn_helix, arabinose operon control protein
CMHHHLFP_01746 4.7e-149 K Helix-turn-helix domain, rpiR family
CMHHHLFP_01747 7.7e-202 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
CMHHHLFP_01748 3.7e-157 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CMHHHLFP_01749 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMHHHLFP_01750 1.6e-298 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMHHHLFP_01751 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMHHHLFP_01752 2.5e-158 K CAT RNA binding domain
CMHHHLFP_01753 0.0 M Leucine-rich repeat (LRR) protein
CMHHHLFP_01755 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CMHHHLFP_01756 1.2e-91
CMHHHLFP_01757 1.6e-182
CMHHHLFP_01758 9.7e-271 S Uncharacterised protein conserved in bacteria (DUF2326)
CMHHHLFP_01759 7.6e-10
CMHHHLFP_01764 1.5e-228 potE E amino acid
CMHHHLFP_01765 1.1e-130 M Glycosyl hydrolases family 25
CMHHHLFP_01766 2.6e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
CMHHHLFP_01767 1.2e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHHHLFP_01769 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CMHHHLFP_01770 4.3e-89 gtcA S Teichoic acid glycosylation protein
CMHHHLFP_01771 1.2e-79 fld C Flavodoxin
CMHHHLFP_01772 1.1e-163 map 3.4.11.18 E Methionine Aminopeptidase
CMHHHLFP_01773 4.1e-151 yihY S Belongs to the UPF0761 family
CMHHHLFP_01774 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CMHHHLFP_01775 5.1e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
CMHHHLFP_01776 4.6e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CMHHHLFP_01777 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
CMHHHLFP_01778 1.9e-46
CMHHHLFP_01779 1.5e-177 D Alpha beta
CMHHHLFP_01780 6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMHHHLFP_01781 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
CMHHHLFP_01782 9.1e-86
CMHHHLFP_01783 1.2e-71
CMHHHLFP_01784 9.5e-158 hlyX S Transporter associated domain
CMHHHLFP_01785 1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMHHHLFP_01786 6.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
CMHHHLFP_01787 0.0 clpE O Belongs to the ClpA ClpB family
CMHHHLFP_01788 8.5e-41 ptsH G phosphocarrier protein HPR
CMHHHLFP_01789 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMHHHLFP_01790 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CMHHHLFP_01791 8.8e-128 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CMHHHLFP_01792 1.4e-161 coiA 3.6.4.12 S Competence protein
CMHHHLFP_01793 1.2e-114 yjbH Q Thioredoxin
CMHHHLFP_01794 9.5e-112 yjbK S CYTH
CMHHHLFP_01795 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
CMHHHLFP_01796 1.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMHHHLFP_01797 8.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMHHHLFP_01798 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
CMHHHLFP_01799 2e-118 S SNARE associated Golgi protein
CMHHHLFP_01800 1.7e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CMHHHLFP_01801 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
CMHHHLFP_01802 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
CMHHHLFP_01803 3.2e-212 yubA S AI-2E family transporter
CMHHHLFP_01804 1.3e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMHHHLFP_01805 1.8e-68 WQ51_03320 S Protein of unknown function (DUF1149)
CMHHHLFP_01806 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CMHHHLFP_01807 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
CMHHHLFP_01808 4.5e-241 S Peptidase M16
CMHHHLFP_01809 2e-132 IQ Enoyl-(Acyl carrier protein) reductase
CMHHHLFP_01810 6.6e-119 ymfM S Helix-turn-helix domain
CMHHHLFP_01811 9.3e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMHHHLFP_01812 7.9e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMHHHLFP_01813 1e-221 rny S Endoribonuclease that initiates mRNA decay
CMHHHLFP_01814 1.8e-212 tagO 2.7.8.33, 2.7.8.35 M transferase
CMHHHLFP_01815 9.6e-118 yvyE 3.4.13.9 S YigZ family
CMHHHLFP_01816 3.3e-247 comFA L Helicase C-terminal domain protein
CMHHHLFP_01817 3.1e-135 comFC S Competence protein
CMHHHLFP_01818 5.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMHHHLFP_01819 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMHHHLFP_01820 3.5e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMHHHLFP_01822 2.4e-256 ica2 GT2 M Glycosyl transferase family group 2
CMHHHLFP_01823 2.2e-175
CMHHHLFP_01824 2.1e-228 S SLAP domain
CMHHHLFP_01825 1.1e-207 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CMHHHLFP_01826 7.2e-211 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
CMHHHLFP_01827 0.0 yjbQ P TrkA C-terminal domain protein
CMHHHLFP_01828 9.8e-180 S Oxidoreductase family, NAD-binding Rossmann fold
CMHHHLFP_01829 7.4e-141
CMHHHLFP_01830 1.5e-135
CMHHHLFP_01831 2.5e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMHHHLFP_01832 1.8e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CMHHHLFP_01833 1.6e-102 G Aldose 1-epimerase
CMHHHLFP_01834 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMHHHLFP_01835 6.4e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMHHHLFP_01836 0.0 XK27_08315 M Sulfatase
CMHHHLFP_01837 6.2e-268 S Fibronectin type III domain
CMHHHLFP_01838 3.3e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMHHHLFP_01839 3.3e-56
CMHHHLFP_01841 7.2e-258 pepC 3.4.22.40 E aminopeptidase
CMHHHLFP_01842 1.2e-125 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMHHHLFP_01843 5e-293 oppA E ABC transporter, substratebinding protein
CMHHHLFP_01844 4.6e-307 oppA E ABC transporter, substratebinding protein
CMHHHLFP_01845 7.5e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMHHHLFP_01846 1.1e-143 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMHHHLFP_01847 4e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMHHHLFP_01848 2.2e-201 oppD P Belongs to the ABC transporter superfamily
CMHHHLFP_01849 1.9e-175 oppF P Belongs to the ABC transporter superfamily
CMHHHLFP_01850 2.3e-256 pepC 3.4.22.40 E aminopeptidase
CMHHHLFP_01851 2.4e-69 hsp O Belongs to the small heat shock protein (HSP20) family
CMHHHLFP_01852 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMHHHLFP_01853 1.3e-114
CMHHHLFP_01855 4.2e-112 E Belongs to the SOS response-associated peptidase family
CMHHHLFP_01856 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMHHHLFP_01857 6.5e-92 comEB 3.5.4.12 F MafB19-like deaminase
CMHHHLFP_01858 3.4e-109 S TPM domain
CMHHHLFP_01859 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
CMHHHLFP_01860 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMHHHLFP_01861 3.5e-148 tatD L hydrolase, TatD family
CMHHHLFP_01862 1.6e-92 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CMHHHLFP_01863 1.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMHHHLFP_01864 3.5e-39 veg S Biofilm formation stimulator VEG
CMHHHLFP_01865 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CMHHHLFP_01866 1.4e-211 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMHHHLFP_01867 9.6e-89 S SLAP domain
CMHHHLFP_01868 8.4e-90 S SLAP domain
CMHHHLFP_01869 1.5e-86
CMHHHLFP_01870 7.3e-239 S SLAP domain
CMHHHLFP_01871 1.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMHHHLFP_01872 5.2e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMHHHLFP_01873 7.7e-129 K Helix-turn-helix domain, rpiR family
CMHHHLFP_01874 1.2e-231 ptcC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHHHLFP_01875 3.3e-169 2.7.1.2 GK ROK family
CMHHHLFP_01876 3.9e-44
CMHHHLFP_01877 9e-161 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)