ORF_ID e_value Gene_name EC_number CAZy COGs Description
IPEPIGIO_00001 5.1e-103 S Protein of unknown function (DUF1211)
IPEPIGIO_00002 3.7e-34
IPEPIGIO_00003 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IPEPIGIO_00004 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IPEPIGIO_00005 8.6e-98 J glyoxalase III activity
IPEPIGIO_00006 1.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
IPEPIGIO_00007 5.9e-91 rmeB K transcriptional regulator, MerR family
IPEPIGIO_00008 2.1e-55 S Domain of unknown function (DU1801)
IPEPIGIO_00009 7.6e-166 corA P CorA-like Mg2+ transporter protein
IPEPIGIO_00010 4.6e-216 ysaA V RDD family
IPEPIGIO_00011 3.8e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
IPEPIGIO_00012 6.6e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IPEPIGIO_00013 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IPEPIGIO_00014 2.7e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IPEPIGIO_00015 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IPEPIGIO_00016 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPEPIGIO_00017 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IPEPIGIO_00018 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IPEPIGIO_00019 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IPEPIGIO_00020 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IPEPIGIO_00021 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPEPIGIO_00022 3.6e-55 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IPEPIGIO_00023 3.1e-136 terC P membrane
IPEPIGIO_00024 2.2e-151 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IPEPIGIO_00025 1.3e-257 npr 1.11.1.1 C NADH oxidase
IPEPIGIO_00026 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
IPEPIGIO_00027 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IPEPIGIO_00028 3.1e-176 XK27_08835 S ABC transporter
IPEPIGIO_00029 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IPEPIGIO_00030 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
IPEPIGIO_00031 4e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
IPEPIGIO_00032 5e-162 degV S Uncharacterised protein, DegV family COG1307
IPEPIGIO_00033 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPEPIGIO_00034 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
IPEPIGIO_00035 6e-39
IPEPIGIO_00036 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPEPIGIO_00037 2e-106 3.2.2.20 K acetyltransferase
IPEPIGIO_00038 7.8e-296 S ABC transporter, ATP-binding protein
IPEPIGIO_00039 5.6e-217 2.7.7.65 T diguanylate cyclase
IPEPIGIO_00040 3.3e-33
IPEPIGIO_00041 2e-35
IPEPIGIO_00042 3.3e-80 K AsnC family
IPEPIGIO_00043 3.1e-172 ykfC 3.4.14.13 M NlpC/P60 family
IPEPIGIO_00044 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_00046 3.8e-23
IPEPIGIO_00047 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
IPEPIGIO_00048 9.8e-214 yceI EGP Major facilitator Superfamily
IPEPIGIO_00049 4.2e-47
IPEPIGIO_00050 6.5e-91 S ECF-type riboflavin transporter, S component
IPEPIGIO_00051 1.9e-105 sip L Belongs to the 'phage' integrase family
IPEPIGIO_00052 3.1e-27 K Cro/C1-type HTH DNA-binding domain
IPEPIGIO_00054 2.6e-97 S Phage regulatory protein Rha (Phage_pRha)
IPEPIGIO_00055 2.5e-40
IPEPIGIO_00058 1.4e-21
IPEPIGIO_00059 2e-27
IPEPIGIO_00060 8.3e-137 L Primase C terminal 1 (PriCT-1)
IPEPIGIO_00061 2.1e-263 S Virulence-associated protein E
IPEPIGIO_00062 1.5e-60
IPEPIGIO_00063 6.9e-27
IPEPIGIO_00064 2.6e-47
IPEPIGIO_00066 2.6e-169 EG EamA-like transporter family
IPEPIGIO_00067 2.3e-38 gcvR T Belongs to the UPF0237 family
IPEPIGIO_00068 3e-243 XK27_08635 S UPF0210 protein
IPEPIGIO_00069 1.6e-134 K response regulator
IPEPIGIO_00070 2.9e-287 yclK 2.7.13.3 T Histidine kinase
IPEPIGIO_00071 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
IPEPIGIO_00072 9.7e-155 glcU U sugar transport
IPEPIGIO_00073 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
IPEPIGIO_00074 6.8e-24
IPEPIGIO_00075 0.0 macB3 V ABC transporter, ATP-binding protein
IPEPIGIO_00076 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IPEPIGIO_00077 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
IPEPIGIO_00078 1.6e-16
IPEPIGIO_00079 5.5e-18
IPEPIGIO_00080 1.5e-14
IPEPIGIO_00081 4.7e-16
IPEPIGIO_00082 1.5e-14
IPEPIGIO_00083 3.8e-93 M MucBP domain
IPEPIGIO_00084 2.5e-108 M MucBP domain
IPEPIGIO_00085 0.0 bztC D nuclear chromosome segregation
IPEPIGIO_00086 7.3e-83 K MarR family
IPEPIGIO_00087 1.4e-43
IPEPIGIO_00088 2e-38
IPEPIGIO_00089 2.1e-224 sip L Belongs to the 'phage' integrase family
IPEPIGIO_00090 1.7e-15 K Cro/C1-type HTH DNA-binding domain
IPEPIGIO_00093 6.6e-08
IPEPIGIO_00095 8.7e-34
IPEPIGIO_00097 5.9e-146 L DNA replication protein
IPEPIGIO_00098 1.6e-263 S Virulence-associated protein E
IPEPIGIO_00099 7e-74
IPEPIGIO_00101 3.1e-48 S head-tail joining protein
IPEPIGIO_00102 7.7e-67 L HNH endonuclease
IPEPIGIO_00103 1.6e-82 terS L overlaps another CDS with the same product name
IPEPIGIO_00104 0.0 terL S overlaps another CDS with the same product name
IPEPIGIO_00106 5e-204 S Phage portal protein
IPEPIGIO_00107 2.1e-277 S Caudovirus prohead serine protease
IPEPIGIO_00108 2.3e-38 S Phage gp6-like head-tail connector protein
IPEPIGIO_00109 2.3e-55
IPEPIGIO_00112 8.9e-30
IPEPIGIO_00114 9.6e-219 int L Belongs to the 'phage' integrase family
IPEPIGIO_00116 2.1e-37
IPEPIGIO_00119 3.3e-35 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
IPEPIGIO_00120 2.7e-26
IPEPIGIO_00121 3.6e-29 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IPEPIGIO_00123 4.1e-13 S DNA/RNA non-specific endonuclease
IPEPIGIO_00126 1.1e-13 E IrrE N-terminal-like domain
IPEPIGIO_00127 3e-66 S protein disulfide oxidoreductase activity
IPEPIGIO_00128 1.4e-38 S protein disulfide oxidoreductase activity
IPEPIGIO_00130 1.3e-53
IPEPIGIO_00131 3.7e-85
IPEPIGIO_00133 1.6e-54 S Bacteriophage Mu Gam like protein
IPEPIGIO_00134 6.8e-64
IPEPIGIO_00135 1.5e-156 L Domain of unknown function (DUF4373)
IPEPIGIO_00136 1.8e-49
IPEPIGIO_00137 3.5e-83
IPEPIGIO_00138 6e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IPEPIGIO_00140 7.2e-30 S YopX protein
IPEPIGIO_00142 1.2e-79 arpU S Phage transcriptional regulator, ArpU family
IPEPIGIO_00149 3.9e-13 V HNH nucleases
IPEPIGIO_00151 1.6e-51 S Terminase small subunit
IPEPIGIO_00153 2.8e-246 S Phage terminase, large subunit
IPEPIGIO_00154 2.7e-310 S Phage portal protein, SPP1 Gp6-like
IPEPIGIO_00155 4.1e-170 S Phage Mu protein F like protein
IPEPIGIO_00156 3.6e-69 S Domain of unknown function (DUF4355)
IPEPIGIO_00157 1.4e-187 gpG
IPEPIGIO_00158 2.1e-58 S Phage gp6-like head-tail connector protein
IPEPIGIO_00159 1.4e-49
IPEPIGIO_00160 1.5e-90
IPEPIGIO_00161 1.5e-66
IPEPIGIO_00162 2.8e-94
IPEPIGIO_00163 3.9e-84 S Phage tail assembly chaperone protein, TAC
IPEPIGIO_00165 0.0 D NLP P60 protein
IPEPIGIO_00166 6.8e-125 D NLP P60 protein
IPEPIGIO_00167 1.1e-133 S phage tail
IPEPIGIO_00168 5.8e-285 M Prophage endopeptidase tail
IPEPIGIO_00169 1.5e-162 E GDSL-like Lipase/Acylhydrolase family
IPEPIGIO_00170 6.7e-83 S Domain of unknown function (DUF2479)
IPEPIGIO_00171 1.4e-13 S Domain of unknown function (DUF2479)
IPEPIGIO_00174 3.4e-45
IPEPIGIO_00175 3.8e-21
IPEPIGIO_00177 3.3e-206 lys M Glycosyl hydrolases family 25
IPEPIGIO_00178 1.5e-34 S Haemolysin XhlA
IPEPIGIO_00179 1e-31 hol S Bacteriophage holin
IPEPIGIO_00180 3.3e-61 V Abortive infection bacteriophage resistance protein
IPEPIGIO_00182 1.3e-132 yxkH G Polysaccharide deacetylase
IPEPIGIO_00183 3.3e-65 S Protein of unknown function (DUF1093)
IPEPIGIO_00184 9.6e-311 ycfI V ABC transporter, ATP-binding protein
IPEPIGIO_00185 0.0 yfiC V ABC transporter
IPEPIGIO_00186 2.8e-126
IPEPIGIO_00187 1.9e-58
IPEPIGIO_00188 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IPEPIGIO_00189 5.2e-29
IPEPIGIO_00190 1.2e-191 ampC V Beta-lactamase
IPEPIGIO_00191 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
IPEPIGIO_00192 6.5e-136 cobQ S glutamine amidotransferase
IPEPIGIO_00193 4.4e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IPEPIGIO_00194 9.3e-109 tdk 2.7.1.21 F thymidine kinase
IPEPIGIO_00195 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPEPIGIO_00196 3.9e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IPEPIGIO_00197 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IPEPIGIO_00198 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPEPIGIO_00199 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPEPIGIO_00200 1e-232 pyrP F Permease
IPEPIGIO_00201 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
IPEPIGIO_00202 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPEPIGIO_00203 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPEPIGIO_00204 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPEPIGIO_00205 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPEPIGIO_00206 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPEPIGIO_00207 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPEPIGIO_00208 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IPEPIGIO_00209 3.7e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPEPIGIO_00210 2.1e-102 J Acetyltransferase (GNAT) domain
IPEPIGIO_00211 2.7e-180 mbl D Cell shape determining protein MreB Mrl
IPEPIGIO_00212 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IPEPIGIO_00213 1.2e-32 S Protein of unknown function (DUF2969)
IPEPIGIO_00214 9.3e-220 rodA D Belongs to the SEDS family
IPEPIGIO_00215 3.6e-48 gcsH2 E glycine cleavage
IPEPIGIO_00216 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPEPIGIO_00217 1.4e-111 metI U ABC transporter permease
IPEPIGIO_00218 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
IPEPIGIO_00219 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
IPEPIGIO_00220 1.6e-177 S Protein of unknown function (DUF2785)
IPEPIGIO_00221 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IPEPIGIO_00222 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IPEPIGIO_00223 7.1e-297 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IPEPIGIO_00224 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IPEPIGIO_00225 1.5e-200 bla2 3.5.2.6 V Beta-lactamase enzyme family
IPEPIGIO_00226 6.2e-82 usp6 T universal stress protein
IPEPIGIO_00227 1.5e-38
IPEPIGIO_00228 8e-238 rarA L recombination factor protein RarA
IPEPIGIO_00229 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IPEPIGIO_00230 1.9e-43 czrA K Helix-turn-helix domain
IPEPIGIO_00231 2e-109 S Protein of unknown function (DUF1648)
IPEPIGIO_00232 7.3e-80 yueI S Protein of unknown function (DUF1694)
IPEPIGIO_00233 5.2e-113 yktB S Belongs to the UPF0637 family
IPEPIGIO_00234 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPEPIGIO_00235 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
IPEPIGIO_00236 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IPEPIGIO_00237 8.3e-218 iscS2 2.8.1.7 E Aminotransferase class V
IPEPIGIO_00238 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPEPIGIO_00239 6.8e-234 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IPEPIGIO_00240 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IPEPIGIO_00241 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IPEPIGIO_00242 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IPEPIGIO_00243 1.3e-116 radC L DNA repair protein
IPEPIGIO_00244 2.8e-161 mreB D cell shape determining protein MreB
IPEPIGIO_00245 7.6e-144 mreC M Involved in formation and maintenance of cell shape
IPEPIGIO_00246 1.2e-88 mreD M rod shape-determining protein MreD
IPEPIGIO_00247 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IPEPIGIO_00248 1.2e-146 minD D Belongs to the ParA family
IPEPIGIO_00249 4.6e-109 glnP P ABC transporter permease
IPEPIGIO_00250 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPEPIGIO_00251 1.5e-155 aatB ET ABC transporter substrate-binding protein
IPEPIGIO_00252 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
IPEPIGIO_00253 3.2e-231 ymfF S Peptidase M16 inactive domain protein
IPEPIGIO_00254 2.9e-251 ymfH S Peptidase M16
IPEPIGIO_00255 5.7e-110 ymfM S Helix-turn-helix domain
IPEPIGIO_00256 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPEPIGIO_00257 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
IPEPIGIO_00258 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPEPIGIO_00259 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
IPEPIGIO_00260 2.7e-154 ymdB S YmdB-like protein
IPEPIGIO_00261 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPEPIGIO_00262 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IPEPIGIO_00263 0.0 L Transposase
IPEPIGIO_00264 3.1e-71
IPEPIGIO_00265 0.0 S Bacterial membrane protein YfhO
IPEPIGIO_00266 9.6e-89
IPEPIGIO_00267 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IPEPIGIO_00268 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IPEPIGIO_00269 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IPEPIGIO_00270 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IPEPIGIO_00271 2.8e-29 yajC U Preprotein translocase
IPEPIGIO_00272 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPEPIGIO_00273 2e-177 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IPEPIGIO_00274 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IPEPIGIO_00275 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPEPIGIO_00276 2.4e-43 yrzL S Belongs to the UPF0297 family
IPEPIGIO_00277 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPEPIGIO_00278 1.6e-48 yrzB S Belongs to the UPF0473 family
IPEPIGIO_00279 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IPEPIGIO_00280 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IPEPIGIO_00281 3.3e-52 trxA O Belongs to the thioredoxin family
IPEPIGIO_00282 2.9e-125 yslB S Protein of unknown function (DUF2507)
IPEPIGIO_00283 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IPEPIGIO_00284 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPEPIGIO_00285 9.5e-97 S Phosphoesterase
IPEPIGIO_00286 6.5e-87 ykuL S (CBS) domain
IPEPIGIO_00287 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IPEPIGIO_00288 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IPEPIGIO_00289 2.6e-158 ykuT M mechanosensitive ion channel
IPEPIGIO_00290 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IPEPIGIO_00291 2.8e-56
IPEPIGIO_00292 5.2e-19 K helix_turn_helix, mercury resistance
IPEPIGIO_00293 6e-29 K helix_turn_helix, mercury resistance
IPEPIGIO_00294 3.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IPEPIGIO_00295 1.9e-181 ccpA K catabolite control protein A
IPEPIGIO_00296 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IPEPIGIO_00297 1.6e-49 S DsrE/DsrF-like family
IPEPIGIO_00298 8.3e-131 yebC K Transcriptional regulatory protein
IPEPIGIO_00299 8.3e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPEPIGIO_00300 2.1e-174 comGA NU Type II IV secretion system protein
IPEPIGIO_00301 1.3e-188 comGB NU type II secretion system
IPEPIGIO_00302 5.5e-43 comGC U competence protein ComGC
IPEPIGIO_00303 3.2e-83 gspG NU general secretion pathway protein
IPEPIGIO_00304 8.6e-20
IPEPIGIO_00305 4.5e-88 S Prokaryotic N-terminal methylation motif
IPEPIGIO_00307 3.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
IPEPIGIO_00308 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPEPIGIO_00309 5.3e-251 cycA E Amino acid permease
IPEPIGIO_00310 4.4e-117 S Calcineurin-like phosphoesterase
IPEPIGIO_00311 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IPEPIGIO_00312 1.5e-80 yutD S Protein of unknown function (DUF1027)
IPEPIGIO_00313 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IPEPIGIO_00314 1.8e-116 S Protein of unknown function (DUF1461)
IPEPIGIO_00315 1.9e-118 dedA S SNARE-like domain protein
IPEPIGIO_00316 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPEPIGIO_00317 1.6e-75 yugI 5.3.1.9 J general stress protein
IPEPIGIO_00318 1.7e-88 L Helix-turn-helix domain
IPEPIGIO_00319 7.2e-197 K Helix-turn-helix domain
IPEPIGIO_00320 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
IPEPIGIO_00321 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
IPEPIGIO_00322 4.1e-53 yitW S Iron-sulfur cluster assembly protein
IPEPIGIO_00323 2.8e-263 P Sodium:sulfate symporter transmembrane region
IPEPIGIO_00324 1.8e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPEPIGIO_00325 2.6e-183 aroF 2.5.1.54 E DAHP synthetase I family
IPEPIGIO_00326 1.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPEPIGIO_00327 8.5e-44 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPEPIGIO_00328 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPEPIGIO_00329 2.5e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IPEPIGIO_00330 2.2e-173 ywhK S Membrane
IPEPIGIO_00331 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
IPEPIGIO_00332 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IPEPIGIO_00333 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPEPIGIO_00334 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IPEPIGIO_00335 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPEPIGIO_00336 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPEPIGIO_00337 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPEPIGIO_00338 9.8e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IPEPIGIO_00339 3.5e-142 cad S FMN_bind
IPEPIGIO_00340 0.0 ndh 1.6.99.3 C NADH dehydrogenase
IPEPIGIO_00341 7.2e-86 ynhH S NusG domain II
IPEPIGIO_00342 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
IPEPIGIO_00343 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IPEPIGIO_00344 2.1e-61 rplQ J Ribosomal protein L17
IPEPIGIO_00345 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPEPIGIO_00346 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPEPIGIO_00347 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPEPIGIO_00348 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPEPIGIO_00349 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IPEPIGIO_00350 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IPEPIGIO_00351 6.3e-70 rplO J Binds to the 23S rRNA
IPEPIGIO_00352 2.2e-24 rpmD J Ribosomal protein L30
IPEPIGIO_00353 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPEPIGIO_00354 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPEPIGIO_00355 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPEPIGIO_00356 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPEPIGIO_00357 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPEPIGIO_00358 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPEPIGIO_00359 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPEPIGIO_00360 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPEPIGIO_00361 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
IPEPIGIO_00362 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPEPIGIO_00363 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPEPIGIO_00364 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPEPIGIO_00365 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPEPIGIO_00366 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPEPIGIO_00367 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IPEPIGIO_00368 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IPEPIGIO_00369 1.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPEPIGIO_00370 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IPEPIGIO_00371 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPEPIGIO_00372 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IPEPIGIO_00373 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPEPIGIO_00374 1.6e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IPEPIGIO_00375 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPEPIGIO_00376 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPEPIGIO_00377 1.5e-109 K Bacterial regulatory proteins, tetR family
IPEPIGIO_00378 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IPEPIGIO_00379 6.9e-78 ctsR K Belongs to the CtsR family
IPEPIGIO_00387 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPEPIGIO_00388 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IPEPIGIO_00389 9.4e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IPEPIGIO_00390 1.6e-263 lysP E amino acid
IPEPIGIO_00391 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IPEPIGIO_00392 3.6e-91 K Transcriptional regulator
IPEPIGIO_00393 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
IPEPIGIO_00394 2e-154 I alpha/beta hydrolase fold
IPEPIGIO_00395 3.9e-119 lssY 3.6.1.27 I phosphatase
IPEPIGIO_00396 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IPEPIGIO_00397 2.2e-76 S Threonine/Serine exporter, ThrE
IPEPIGIO_00398 1.5e-130 thrE S Putative threonine/serine exporter
IPEPIGIO_00399 6e-31 cspC K Cold shock protein
IPEPIGIO_00400 2e-120 sirR K iron dependent repressor
IPEPIGIO_00401 2.6e-58
IPEPIGIO_00402 1.7e-84 merR K MerR HTH family regulatory protein
IPEPIGIO_00403 4.8e-91 lmrB EGP Major facilitator Superfamily
IPEPIGIO_00404 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
IPEPIGIO_00405 2.3e-82
IPEPIGIO_00406 4.4e-40
IPEPIGIO_00407 2.1e-244 cycA E Amino acid permease
IPEPIGIO_00408 2.2e-17 L Helix-turn-helix domain
IPEPIGIO_00409 3.8e-108 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_00410 1.6e-70 rfbP M Bacterial sugar transferase
IPEPIGIO_00411 2.7e-31 L Transposase
IPEPIGIO_00412 1.6e-196 tra L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_00413 6e-140 S Oxidoreductase family, NAD-binding Rossmann fold
IPEPIGIO_00414 6.1e-196 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_00415 3.8e-53
IPEPIGIO_00416 1.4e-175 L Integrase core domain
IPEPIGIO_00417 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IPEPIGIO_00418 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPEPIGIO_00419 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IPEPIGIO_00420 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPEPIGIO_00421 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IPEPIGIO_00422 1.1e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IPEPIGIO_00423 3.1e-74 yabR J RNA binding
IPEPIGIO_00424 1.1e-63 divIC D Septum formation initiator
IPEPIGIO_00426 2.2e-42 yabO J S4 domain protein
IPEPIGIO_00427 1.4e-282 yabM S Polysaccharide biosynthesis protein
IPEPIGIO_00428 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IPEPIGIO_00429 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IPEPIGIO_00430 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IPEPIGIO_00431 1.2e-263 S Putative peptidoglycan binding domain
IPEPIGIO_00432 6.2e-114 S (CBS) domain
IPEPIGIO_00433 4.1e-84 S QueT transporter
IPEPIGIO_00434 3.6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPEPIGIO_00435 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
IPEPIGIO_00436 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IPEPIGIO_00437 2.6e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IPEPIGIO_00438 3.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IPEPIGIO_00439 2.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IPEPIGIO_00440 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IPEPIGIO_00441 1.9e-133 P ATPases associated with a variety of cellular activities
IPEPIGIO_00442 1.1e-128 ssuC2 U Binding-protein-dependent transport system inner membrane component
IPEPIGIO_00443 2.9e-193 P ABC transporter, substratebinding protein
IPEPIGIO_00444 0.0 kup P Transport of potassium into the cell
IPEPIGIO_00445 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
IPEPIGIO_00446 2.1e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPEPIGIO_00447 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IPEPIGIO_00448 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IPEPIGIO_00449 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IPEPIGIO_00450 2e-146
IPEPIGIO_00451 4.6e-139 htpX O Belongs to the peptidase M48B family
IPEPIGIO_00452 1.7e-91 lemA S LemA family
IPEPIGIO_00453 9.2e-127 srtA 3.4.22.70 M sortase family
IPEPIGIO_00454 3.2e-214 J translation release factor activity
IPEPIGIO_00455 7.8e-41 rpmE2 J Ribosomal protein L31
IPEPIGIO_00456 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPEPIGIO_00457 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPEPIGIO_00458 2.5e-26
IPEPIGIO_00459 6.4e-131 S YheO-like PAS domain
IPEPIGIO_00460 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IPEPIGIO_00461 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IPEPIGIO_00462 4e-229 tdcC E amino acid
IPEPIGIO_00463 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPEPIGIO_00464 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IPEPIGIO_00465 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IPEPIGIO_00466 3.8e-78 ywiB S Domain of unknown function (DUF1934)
IPEPIGIO_00467 4.7e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IPEPIGIO_00468 2.6e-263 ywfO S HD domain protein
IPEPIGIO_00469 2.9e-148 yxeH S hydrolase
IPEPIGIO_00470 2.2e-126
IPEPIGIO_00471 1.1e-184 S DUF218 domain
IPEPIGIO_00472 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPEPIGIO_00473 1.2e-149 bla1 3.5.2.6 V Beta-lactamase enzyme family
IPEPIGIO_00474 3.9e-206 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPEPIGIO_00475 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IPEPIGIO_00476 2.1e-31
IPEPIGIO_00477 1.7e-43 ankB S ankyrin repeats
IPEPIGIO_00478 2.3e-150
IPEPIGIO_00479 3.4e-130 glf 5.4.99.9 M UDP-galactopyranose mutase
IPEPIGIO_00480 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_00481 4.2e-70 S Pyrimidine dimer DNA glycosylase
IPEPIGIO_00482 8.2e-58
IPEPIGIO_00483 5.1e-68 L Putative transposase of IS4/5 family (DUF4096)
IPEPIGIO_00484 1.5e-67 tnp2PF3 L Transposase
IPEPIGIO_00489 1.5e-106 KLT Protein tyrosine kinase
IPEPIGIO_00490 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_00491 1.7e-18 N Cell shape-determining protein MreB
IPEPIGIO_00492 2.1e-139 N Cell shape-determining protein MreB
IPEPIGIO_00493 0.0 S Pfam Methyltransferase
IPEPIGIO_00494 3.3e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
IPEPIGIO_00495 2.2e-298 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IPEPIGIO_00496 4.2e-29
IPEPIGIO_00497 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
IPEPIGIO_00498 1.4e-124 3.6.1.27 I Acid phosphatase homologues
IPEPIGIO_00499 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IPEPIGIO_00500 1.1e-300 ytgP S Polysaccharide biosynthesis protein
IPEPIGIO_00501 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IPEPIGIO_00502 1.9e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IPEPIGIO_00503 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
IPEPIGIO_00504 4.1e-84 uspA T Belongs to the universal stress protein A family
IPEPIGIO_00505 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
IPEPIGIO_00506 1.2e-172 ugpA U Binding-protein-dependent transport system inner membrane component
IPEPIGIO_00507 1.1e-150 ugpE G ABC transporter permease
IPEPIGIO_00508 2.5e-180 ugpB G Bacterial extracellular solute-binding protein
IPEPIGIO_00509 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
IPEPIGIO_00510 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IPEPIGIO_00511 3.9e-179 XK27_06930 V domain protein
IPEPIGIO_00513 3.4e-124 V Transport permease protein
IPEPIGIO_00514 2.3e-156 V ABC transporter
IPEPIGIO_00515 4e-176 K LytTr DNA-binding domain
IPEPIGIO_00517 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPEPIGIO_00518 1.6e-64 K helix_turn_helix, mercury resistance
IPEPIGIO_00519 3.5e-117 GM NAD(P)H-binding
IPEPIGIO_00520 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IPEPIGIO_00521 2.9e-148 S Sucrose-6F-phosphate phosphohydrolase
IPEPIGIO_00522 1.7e-108
IPEPIGIO_00523 7.2e-223 pltK 2.7.13.3 T GHKL domain
IPEPIGIO_00524 1.6e-137 pltR K LytTr DNA-binding domain
IPEPIGIO_00525 4.5e-55
IPEPIGIO_00526 2.5e-59
IPEPIGIO_00527 1.9e-113 S CAAX protease self-immunity
IPEPIGIO_00528 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
IPEPIGIO_00529 1e-90
IPEPIGIO_00530 7.3e-46
IPEPIGIO_00531 0.0 uvrA2 L ABC transporter
IPEPIGIO_00534 5.9e-52
IPEPIGIO_00535 3.5e-10
IPEPIGIO_00536 2.1e-180
IPEPIGIO_00537 1.9e-89 gtcA S Teichoic acid glycosylation protein
IPEPIGIO_00538 3.6e-58 S Protein of unknown function (DUF1516)
IPEPIGIO_00539 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IPEPIGIO_00540 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IPEPIGIO_00541 1.2e-307 S Protein conserved in bacteria
IPEPIGIO_00542 1.6e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
IPEPIGIO_00543 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
IPEPIGIO_00544 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
IPEPIGIO_00545 6.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
IPEPIGIO_00546 0.0 yfbS P Sodium:sulfate symporter transmembrane region
IPEPIGIO_00547 7.6e-92 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IPEPIGIO_00548 1.6e-39 L Transposase
IPEPIGIO_00549 3.6e-26
IPEPIGIO_00550 1.2e-79 L PFAM Integrase catalytic region
IPEPIGIO_00552 2.5e-35 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPEPIGIO_00553 8.2e-207 ica2 GT2 M Glycosyl transferase family group 2
IPEPIGIO_00554 1.2e-286
IPEPIGIO_00555 1.6e-205 ftsW D Belongs to the SEDS family
IPEPIGIO_00556 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IPEPIGIO_00557 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IPEPIGIO_00558 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IPEPIGIO_00559 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPEPIGIO_00560 9.6e-197 ylbL T Belongs to the peptidase S16 family
IPEPIGIO_00561 6.2e-64 comEA L Competence protein ComEA
IPEPIGIO_00562 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
IPEPIGIO_00563 0.0 comEC S Competence protein ComEC
IPEPIGIO_00564 2.7e-186 holA 2.7.7.7 L DNA polymerase III delta subunit
IPEPIGIO_00565 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
IPEPIGIO_00566 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPEPIGIO_00567 7.8e-38 L Helix-turn-helix domain
IPEPIGIO_00568 4.3e-109 L Helix-turn-helix domain
IPEPIGIO_00569 2e-190 mdtG EGP Major Facilitator Superfamily
IPEPIGIO_00570 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPEPIGIO_00571 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPEPIGIO_00572 1e-157 S Tetratricopeptide repeat
IPEPIGIO_00573 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPEPIGIO_00574 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IPEPIGIO_00575 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPEPIGIO_00576 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IPEPIGIO_00577 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IPEPIGIO_00578 9.9e-73 S Iron-sulphur cluster biosynthesis
IPEPIGIO_00579 4.3e-22
IPEPIGIO_00580 9.2e-270 glnPH2 P ABC transporter permease
IPEPIGIO_00581 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPEPIGIO_00582 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IPEPIGIO_00583 2.9e-126 epsB M biosynthesis protein
IPEPIGIO_00584 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IPEPIGIO_00585 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
IPEPIGIO_00586 2.1e-179 cps4D 5.1.3.2 M RmlD substrate binding domain
IPEPIGIO_00587 7.4e-126 tuaA M Bacterial sugar transferase
IPEPIGIO_00588 5.6e-175 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
IPEPIGIO_00589 5e-190 cps4G M Glycosyltransferase Family 4
IPEPIGIO_00590 5e-232
IPEPIGIO_00591 2.3e-176 cps4I M Glycosyltransferase like family 2
IPEPIGIO_00592 4.5e-261 cps4J S Polysaccharide biosynthesis protein
IPEPIGIO_00593 6.5e-251 cpdA S Calcineurin-like phosphoesterase
IPEPIGIO_00594 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
IPEPIGIO_00595 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IPEPIGIO_00596 1.5e-135 fruR K DeoR C terminal sensor domain
IPEPIGIO_00597 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPEPIGIO_00598 3.2e-46
IPEPIGIO_00599 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IPEPIGIO_00600 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IPEPIGIO_00601 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
IPEPIGIO_00602 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IPEPIGIO_00603 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPEPIGIO_00604 1.5e-98 K Helix-turn-helix domain
IPEPIGIO_00605 6.1e-211 EGP Major facilitator Superfamily
IPEPIGIO_00606 8.5e-57 ybjQ S Belongs to the UPF0145 family
IPEPIGIO_00607 1.1e-138 Q Methyltransferase
IPEPIGIO_00608 1.6e-31
IPEPIGIO_00610 2.2e-229 rodA D Cell cycle protein
IPEPIGIO_00611 6.3e-213 opuAB P Binding-protein-dependent transport system inner membrane component
IPEPIGIO_00614 9.8e-106 opuAB P Binding-protein-dependent transport system inner membrane component
IPEPIGIO_00615 7.9e-143 P ATPases associated with a variety of cellular activities
IPEPIGIO_00616 2e-219 lytR5 K Cell envelope-related transcriptional attenuator domain
IPEPIGIO_00617 9.2e-101 L Helix-turn-helix domain
IPEPIGIO_00618 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
IPEPIGIO_00619 3e-66
IPEPIGIO_00620 6.2e-75
IPEPIGIO_00621 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IPEPIGIO_00622 3.7e-87
IPEPIGIO_00623 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPEPIGIO_00624 2.9e-36 ynzC S UPF0291 protein
IPEPIGIO_00625 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
IPEPIGIO_00626 6.4e-119 plsC 2.3.1.51 I Acyltransferase
IPEPIGIO_00627 2.1e-132 yabB 2.1.1.223 L Methyltransferase small domain
IPEPIGIO_00628 7e-39 yazA L GIY-YIG catalytic domain protein
IPEPIGIO_00629 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPEPIGIO_00630 4.7e-134 S Haloacid dehalogenase-like hydrolase
IPEPIGIO_00631 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
IPEPIGIO_00632 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPEPIGIO_00633 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IPEPIGIO_00634 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IPEPIGIO_00635 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPEPIGIO_00636 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
IPEPIGIO_00637 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IPEPIGIO_00638 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IPEPIGIO_00639 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPEPIGIO_00640 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
IPEPIGIO_00641 3.3e-217 nusA K Participates in both transcription termination and antitermination
IPEPIGIO_00642 9.5e-49 ylxR K Protein of unknown function (DUF448)
IPEPIGIO_00643 3.1e-47 ylxQ J ribosomal protein
IPEPIGIO_00644 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPEPIGIO_00645 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPEPIGIO_00646 6.7e-265 ydiN 5.4.99.5 G Major Facilitator
IPEPIGIO_00647 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPEPIGIO_00648 8.5e-93
IPEPIGIO_00649 4.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IPEPIGIO_00650 5.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IPEPIGIO_00651 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPEPIGIO_00652 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPEPIGIO_00653 2.7e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IPEPIGIO_00654 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
IPEPIGIO_00655 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IPEPIGIO_00656 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPEPIGIO_00657 0.0 dnaK O Heat shock 70 kDa protein
IPEPIGIO_00658 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IPEPIGIO_00659 4.4e-198 pbpX2 V Beta-lactamase
IPEPIGIO_00660 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
IPEPIGIO_00661 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPEPIGIO_00662 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
IPEPIGIO_00663 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPEPIGIO_00664 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IPEPIGIO_00665 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IPEPIGIO_00666 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
IPEPIGIO_00669 1.2e-79 L PFAM Integrase catalytic region
IPEPIGIO_00670 1.6e-174 corA P CorA-like Mg2+ transporter protein
IPEPIGIO_00671 1.9e-62 S Protein of unknown function (DUF3397)
IPEPIGIO_00672 1.9e-77 mraZ K Belongs to the MraZ family
IPEPIGIO_00673 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IPEPIGIO_00674 7.5e-54 ftsL D Cell division protein FtsL
IPEPIGIO_00675 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IPEPIGIO_00676 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPEPIGIO_00677 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPEPIGIO_00678 3.4e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPEPIGIO_00679 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IPEPIGIO_00680 2.1e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IPEPIGIO_00681 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPEPIGIO_00682 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IPEPIGIO_00683 1.2e-36 yggT S YGGT family
IPEPIGIO_00684 3.4e-146 ylmH S S4 domain protein
IPEPIGIO_00685 1.2e-86 divIVA D DivIVA domain protein
IPEPIGIO_00686 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPEPIGIO_00687 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPEPIGIO_00688 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IPEPIGIO_00689 4.6e-28
IPEPIGIO_00690 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPEPIGIO_00691 2.6e-214 iscS 2.8.1.7 E Aminotransferase class V
IPEPIGIO_00692 4.9e-57 XK27_04120 S Putative amino acid metabolism
IPEPIGIO_00693 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IPEPIGIO_00694 1.3e-241 ktrB P Potassium uptake protein
IPEPIGIO_00695 2.6e-115 ktrA P domain protein
IPEPIGIO_00696 2.3e-120 N WxL domain surface cell wall-binding
IPEPIGIO_00697 1.9e-192 S Bacterial protein of unknown function (DUF916)
IPEPIGIO_00698 5.5e-267 N domain, Protein
IPEPIGIO_00699 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IPEPIGIO_00700 1.6e-120 S Repeat protein
IPEPIGIO_00701 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IPEPIGIO_00702 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPEPIGIO_00703 2.6e-107 mltD CBM50 M NlpC P60 family protein
IPEPIGIO_00704 1.7e-28
IPEPIGIO_00705 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IPEPIGIO_00706 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPEPIGIO_00707 3.1e-33 ykzG S Belongs to the UPF0356 family
IPEPIGIO_00708 1.6e-85
IPEPIGIO_00709 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPEPIGIO_00710 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IPEPIGIO_00711 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IPEPIGIO_00712 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPEPIGIO_00713 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
IPEPIGIO_00714 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
IPEPIGIO_00715 3.3e-46 yktA S Belongs to the UPF0223 family
IPEPIGIO_00716 3.5e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IPEPIGIO_00717 0.0 typA T GTP-binding protein TypA
IPEPIGIO_00718 1.1e-172
IPEPIGIO_00719 1.2e-103
IPEPIGIO_00720 3.9e-11 ica2 GT2 M Glycosyl transferase family group 2
IPEPIGIO_00721 1.2e-102 2.7.7.65 T Diguanylate cyclase, GGDEF domain
IPEPIGIO_00722 6.8e-127 yliE T EAL domain
IPEPIGIO_00723 3.2e-103 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IPEPIGIO_00724 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IPEPIGIO_00725 2e-80
IPEPIGIO_00726 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IPEPIGIO_00727 2.6e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IPEPIGIO_00728 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPEPIGIO_00729 4.9e-22
IPEPIGIO_00730 2.9e-70
IPEPIGIO_00731 1.2e-163 K LysR substrate binding domain
IPEPIGIO_00732 2.4e-243 P Sodium:sulfate symporter transmembrane region
IPEPIGIO_00733 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
IPEPIGIO_00734 5.1e-265 S response to antibiotic
IPEPIGIO_00735 2.8e-134 S zinc-ribbon domain
IPEPIGIO_00737 3.2e-37
IPEPIGIO_00738 8.3e-108 aroD S Alpha/beta hydrolase family
IPEPIGIO_00739 1.7e-15 aroD S Alpha/beta hydrolase family
IPEPIGIO_00740 2.6e-176 S Phosphotransferase system, EIIC
IPEPIGIO_00741 2.5e-269 I acetylesterase activity
IPEPIGIO_00742 6.2e-223 sdrF M Collagen binding domain
IPEPIGIO_00743 1.1e-159 yicL EG EamA-like transporter family
IPEPIGIO_00744 4.4e-129 E lipolytic protein G-D-S-L family
IPEPIGIO_00745 1.7e-176 4.1.1.52 S Amidohydrolase
IPEPIGIO_00746 2.5e-112 K Transcriptional regulator C-terminal region
IPEPIGIO_00747 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
IPEPIGIO_00748 4.2e-161 ypbG 2.7.1.2 GK ROK family
IPEPIGIO_00749 0.0 ybfG M peptidoglycan-binding domain-containing protein
IPEPIGIO_00750 5.6e-89
IPEPIGIO_00751 0.0 lmrA 3.6.3.44 V ABC transporter
IPEPIGIO_00752 5e-93 rmaB K Transcriptional regulator, MarR family
IPEPIGIO_00753 7.1e-159 ccpB 5.1.1.1 K lacI family
IPEPIGIO_00754 3e-121 yceE S haloacid dehalogenase-like hydrolase
IPEPIGIO_00755 1.3e-119 drgA C Nitroreductase family
IPEPIGIO_00756 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
IPEPIGIO_00757 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
IPEPIGIO_00758 8.7e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
IPEPIGIO_00759 1.5e-167 XK27_00670 S ABC transporter
IPEPIGIO_00760 1e-260
IPEPIGIO_00761 7.3e-62
IPEPIGIO_00762 5.1e-190 S Cell surface protein
IPEPIGIO_00763 2.3e-91 S WxL domain surface cell wall-binding
IPEPIGIO_00764 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
IPEPIGIO_00765 1.8e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
IPEPIGIO_00766 3.3e-124 livF E ABC transporter
IPEPIGIO_00767 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
IPEPIGIO_00768 5.3e-141 livM E Branched-chain amino acid transport system / permease component
IPEPIGIO_00769 2.1e-149 livH U Branched-chain amino acid transport system / permease component
IPEPIGIO_00770 5.4e-212 livJ E Receptor family ligand binding region
IPEPIGIO_00772 7e-33
IPEPIGIO_00773 2.9e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPEPIGIO_00774 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IPEPIGIO_00775 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IPEPIGIO_00776 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
IPEPIGIO_00777 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
IPEPIGIO_00778 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IPEPIGIO_00779 1.1e-147 cof S haloacid dehalogenase-like hydrolase
IPEPIGIO_00780 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
IPEPIGIO_00781 9.4e-77
IPEPIGIO_00782 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPEPIGIO_00783 6.8e-116 ybbL S ABC transporter, ATP-binding protein
IPEPIGIO_00784 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
IPEPIGIO_00785 2.6e-205 S DUF218 domain
IPEPIGIO_00786 4.1e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IPEPIGIO_00787 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IPEPIGIO_00788 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
IPEPIGIO_00789 2.1e-126 S Putative adhesin
IPEPIGIO_00790 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
IPEPIGIO_00791 9.8e-52 K Transcriptional regulator
IPEPIGIO_00792 5.8e-79 KT response to antibiotic
IPEPIGIO_00793 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IPEPIGIO_00794 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPEPIGIO_00795 8.1e-123 tcyB E ABC transporter
IPEPIGIO_00796 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IPEPIGIO_00797 1.9e-236 EK Aminotransferase, class I
IPEPIGIO_00798 2.1e-168 K LysR substrate binding domain
IPEPIGIO_00799 3.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_00800 0.0 S Bacterial membrane protein YfhO
IPEPIGIO_00801 1.2e-225 nupG F Nucleoside
IPEPIGIO_00802 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IPEPIGIO_00803 7.9e-149 noc K Belongs to the ParB family
IPEPIGIO_00804 1.8e-136 soj D Sporulation initiation inhibitor
IPEPIGIO_00805 2.4e-156 spo0J K Belongs to the ParB family
IPEPIGIO_00806 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
IPEPIGIO_00807 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IPEPIGIO_00808 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
IPEPIGIO_00809 5.2e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPEPIGIO_00810 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IPEPIGIO_00811 5.5e-124 yoaK S Protein of unknown function (DUF1275)
IPEPIGIO_00812 3.2e-124 K response regulator
IPEPIGIO_00813 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
IPEPIGIO_00814 2.1e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IPEPIGIO_00815 6.4e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IPEPIGIO_00816 5.1e-131 azlC E branched-chain amino acid
IPEPIGIO_00817 2.3e-54 azlD S branched-chain amino acid
IPEPIGIO_00818 3.6e-110 S membrane transporter protein
IPEPIGIO_00819 4.8e-55
IPEPIGIO_00820 3.9e-75 S Psort location Cytoplasmic, score
IPEPIGIO_00821 6e-97 S Domain of unknown function (DUF4352)
IPEPIGIO_00822 2.9e-23 S Protein of unknown function (DUF4064)
IPEPIGIO_00823 7.5e-86 KLT Protein tyrosine kinase
IPEPIGIO_00824 1.2e-112 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
IPEPIGIO_00825 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IPEPIGIO_00826 1.3e-128 K Helix-turn-helix domain, rpiR family
IPEPIGIO_00827 8.5e-159 S Alpha beta hydrolase
IPEPIGIO_00828 9.9e-112 GM NmrA-like family
IPEPIGIO_00829 7e-77 S Uncharacterized protein conserved in bacteria (DUF2255)
IPEPIGIO_00830 1.9e-161 K Transcriptional regulator
IPEPIGIO_00831 1.9e-172 C nadph quinone reductase
IPEPIGIO_00832 6.3e-14 S Alpha beta hydrolase
IPEPIGIO_00833 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPEPIGIO_00834 4e-102 desR K helix_turn_helix, Lux Regulon
IPEPIGIO_00835 2.8e-207 desK 2.7.13.3 T Histidine kinase
IPEPIGIO_00836 3.1e-136 yvfS V ABC-2 type transporter
IPEPIGIO_00837 5.2e-159 yvfR V ABC transporter
IPEPIGIO_00839 6e-82 K Acetyltransferase (GNAT) domain
IPEPIGIO_00840 2.4e-72 K MarR family
IPEPIGIO_00841 3.8e-114 S Psort location CytoplasmicMembrane, score
IPEPIGIO_00842 2.6e-12 yjdF S Protein of unknown function (DUF2992)
IPEPIGIO_00843 5.6e-161 V ABC transporter, ATP-binding protein
IPEPIGIO_00844 5.2e-128 S ABC-2 family transporter protein
IPEPIGIO_00845 1.5e-197
IPEPIGIO_00846 5.9e-202
IPEPIGIO_00847 4.8e-165 ytrB V ABC transporter, ATP-binding protein
IPEPIGIO_00848 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
IPEPIGIO_00849 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IPEPIGIO_00850 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IPEPIGIO_00851 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IPEPIGIO_00852 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IPEPIGIO_00853 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
IPEPIGIO_00854 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IPEPIGIO_00855 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IPEPIGIO_00856 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPEPIGIO_00857 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
IPEPIGIO_00858 2.6e-71 yqeY S YqeY-like protein
IPEPIGIO_00859 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IPEPIGIO_00860 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IPEPIGIO_00861 7.7e-109 C Enoyl-(Acyl carrier protein) reductase
IPEPIGIO_00862 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPEPIGIO_00863 6.6e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPEPIGIO_00864 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IPEPIGIO_00865 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPEPIGIO_00866 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IPEPIGIO_00867 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
IPEPIGIO_00868 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IPEPIGIO_00869 3.9e-159 yniA G Fructosamine kinase
IPEPIGIO_00870 6.5e-116 3.1.3.18 J HAD-hyrolase-like
IPEPIGIO_00871 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IPEPIGIO_00872 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPEPIGIO_00873 9.6e-58
IPEPIGIO_00874 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IPEPIGIO_00875 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
IPEPIGIO_00876 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IPEPIGIO_00877 1.4e-49
IPEPIGIO_00878 1.4e-49
IPEPIGIO_00879 3.8e-63 S Domain of unknown function (DUF4440)
IPEPIGIO_00880 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
IPEPIGIO_00881 8.2e-48
IPEPIGIO_00882 3.2e-37
IPEPIGIO_00883 2.8e-85 yvbK 3.1.3.25 K GNAT family
IPEPIGIO_00884 3.8e-84
IPEPIGIO_00886 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IPEPIGIO_00887 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IPEPIGIO_00888 2.3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IPEPIGIO_00890 7.5e-121 macB V ABC transporter, ATP-binding protein
IPEPIGIO_00891 0.0 ylbB V ABC transporter permease
IPEPIGIO_00892 4.8e-235 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IPEPIGIO_00893 9.8e-79 K transcriptional regulator, MerR family
IPEPIGIO_00894 3.2e-76 yphH S Cupin domain
IPEPIGIO_00895 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
IPEPIGIO_00896 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IPEPIGIO_00897 4.7e-211 natB CP ABC-2 family transporter protein
IPEPIGIO_00898 7.5e-166 natA S ABC transporter, ATP-binding protein
IPEPIGIO_00899 1.2e-91 ogt 2.1.1.63 L Methyltransferase
IPEPIGIO_00900 5.6e-51 lytE M LysM domain
IPEPIGIO_00901 1.6e-33 lytE M LysM domain protein
IPEPIGIO_00902 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
IPEPIGIO_00903 7.6e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IPEPIGIO_00904 4.8e-151 rlrG K Transcriptional regulator
IPEPIGIO_00905 9.3e-173 S Conserved hypothetical protein 698
IPEPIGIO_00906 1.8e-101 rimL J Acetyltransferase (GNAT) domain
IPEPIGIO_00907 2e-75 S Domain of unknown function (DUF4811)
IPEPIGIO_00908 4.1e-270 lmrB EGP Major facilitator Superfamily
IPEPIGIO_00909 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IPEPIGIO_00910 1.5e-177 ynfM EGP Major facilitator Superfamily
IPEPIGIO_00911 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
IPEPIGIO_00912 1.2e-155 mleP3 S Membrane transport protein
IPEPIGIO_00913 6.4e-117 S Membrane
IPEPIGIO_00914 1.1e-185 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPEPIGIO_00915 8.1e-99 1.5.1.3 H RibD C-terminal domain
IPEPIGIO_00916 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IPEPIGIO_00917 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
IPEPIGIO_00918 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IPEPIGIO_00919 5.2e-174 hrtB V ABC transporter permease
IPEPIGIO_00920 6.6e-95 S Protein of unknown function (DUF1440)
IPEPIGIO_00921 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPEPIGIO_00922 6.4e-148 KT helix_turn_helix, mercury resistance
IPEPIGIO_00923 1.6e-115 S Protein of unknown function (DUF554)
IPEPIGIO_00924 1.1e-92 yueI S Protein of unknown function (DUF1694)
IPEPIGIO_00925 2e-143 yvpB S Peptidase_C39 like family
IPEPIGIO_00926 9.3e-149 M Glycosyl hydrolases family 25
IPEPIGIO_00927 3.9e-111
IPEPIGIO_00928 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPEPIGIO_00929 1.1e-84 hmpT S Pfam:DUF3816
IPEPIGIO_00930 1.9e-113 EG EamA-like transporter family
IPEPIGIO_00931 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPEPIGIO_00932 5.2e-113 zmp2 O Zinc-dependent metalloprotease
IPEPIGIO_00933 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
IPEPIGIO_00934 9.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IPEPIGIO_00935 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
IPEPIGIO_00936 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IPEPIGIO_00937 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPEPIGIO_00938 3.7e-205 yacL S domain protein
IPEPIGIO_00939 2.6e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPEPIGIO_00940 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IPEPIGIO_00941 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IPEPIGIO_00942 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPEPIGIO_00943 7.7e-97 yacP S YacP-like NYN domain
IPEPIGIO_00944 2.4e-101 sigH K Sigma-70 region 2
IPEPIGIO_00945 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IPEPIGIO_00946 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IPEPIGIO_00947 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
IPEPIGIO_00948 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_00949 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPEPIGIO_00950 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IPEPIGIO_00951 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPEPIGIO_00952 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IPEPIGIO_00953 9.3e-178 F DNA/RNA non-specific endonuclease
IPEPIGIO_00954 1.2e-38 L nuclease
IPEPIGIO_00955 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPEPIGIO_00956 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
IPEPIGIO_00957 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPEPIGIO_00958 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPEPIGIO_00959 6.5e-37 nrdH O Glutaredoxin
IPEPIGIO_00960 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
IPEPIGIO_00961 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IPEPIGIO_00962 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPEPIGIO_00963 1.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPEPIGIO_00964 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPEPIGIO_00965 2.2e-38 yaaL S Protein of unknown function (DUF2508)
IPEPIGIO_00966 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPEPIGIO_00967 2.4e-53 yaaQ S Cyclic-di-AMP receptor
IPEPIGIO_00968 3.3e-186 holB 2.7.7.7 L DNA polymerase III
IPEPIGIO_00969 1e-57 yabA L Involved in initiation control of chromosome replication
IPEPIGIO_00970 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IPEPIGIO_00971 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
IPEPIGIO_00972 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IPEPIGIO_00973 1.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
IPEPIGIO_00974 2.5e-144 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
IPEPIGIO_00975 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
IPEPIGIO_00976 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
IPEPIGIO_00977 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IPEPIGIO_00978 5.1e-190 phnD P Phosphonate ABC transporter
IPEPIGIO_00979 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IPEPIGIO_00980 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IPEPIGIO_00981 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IPEPIGIO_00982 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPEPIGIO_00983 3.3e-307 uup S ABC transporter, ATP-binding protein
IPEPIGIO_00984 1.8e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPEPIGIO_00985 6.1e-109 ydiL S CAAX protease self-immunity
IPEPIGIO_00986 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPEPIGIO_00987 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IPEPIGIO_00988 0.0 ydaO E amino acid
IPEPIGIO_00989 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
IPEPIGIO_00990 4.3e-145 pstS P Phosphate
IPEPIGIO_00991 1.7e-114 yvyE 3.4.13.9 S YigZ family
IPEPIGIO_00992 4.3e-258 comFA L Helicase C-terminal domain protein
IPEPIGIO_00993 1.2e-105 comFC S Competence protein
IPEPIGIO_00994 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPEPIGIO_00995 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IPEPIGIO_00996 4.1e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPEPIGIO_00997 7.9e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
IPEPIGIO_00998 1.5e-132 K response regulator
IPEPIGIO_00999 3.5e-250 phoR 2.7.13.3 T Histidine kinase
IPEPIGIO_01000 1.1e-150 pstS P Phosphate
IPEPIGIO_01001 2.6e-161 pstC P probably responsible for the translocation of the substrate across the membrane
IPEPIGIO_01002 1.5e-155 pstA P Phosphate transport system permease protein PstA
IPEPIGIO_01003 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPEPIGIO_01004 5e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPEPIGIO_01005 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
IPEPIGIO_01006 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
IPEPIGIO_01007 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IPEPIGIO_01008 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IPEPIGIO_01009 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPEPIGIO_01010 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IPEPIGIO_01011 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IPEPIGIO_01012 1.9e-124 yliE T Putative diguanylate phosphodiesterase
IPEPIGIO_01013 3.9e-270 nox C NADH oxidase
IPEPIGIO_01014 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IPEPIGIO_01015 2e-109 yviA S Protein of unknown function (DUF421)
IPEPIGIO_01016 1.1e-61 S Protein of unknown function (DUF3290)
IPEPIGIO_01017 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IPEPIGIO_01018 2.8e-131 yliE T Putative diguanylate phosphodiesterase
IPEPIGIO_01019 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPEPIGIO_01020 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IPEPIGIO_01021 9.2e-212 norA EGP Major facilitator Superfamily
IPEPIGIO_01022 3.6e-117 yfbR S HD containing hydrolase-like enzyme
IPEPIGIO_01023 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IPEPIGIO_01024 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IPEPIGIO_01025 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IPEPIGIO_01026 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IPEPIGIO_01027 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
IPEPIGIO_01028 9.3e-87 S Short repeat of unknown function (DUF308)
IPEPIGIO_01029 1.1e-161 rapZ S Displays ATPase and GTPase activities
IPEPIGIO_01030 1.9e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IPEPIGIO_01031 3.7e-168 whiA K May be required for sporulation
IPEPIGIO_01032 9.9e-289 oppA E ABC transporter, substratebinding protein
IPEPIGIO_01033 7.4e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPEPIGIO_01034 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IPEPIGIO_01036 4.2e-245 rpoN K Sigma-54 factor, core binding domain
IPEPIGIO_01037 7.3e-189 cggR K Putative sugar-binding domain
IPEPIGIO_01038 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPEPIGIO_01039 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IPEPIGIO_01040 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IPEPIGIO_01041 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IPEPIGIO_01042 2e-131
IPEPIGIO_01043 4.6e-115 clcA P chloride
IPEPIGIO_01044 1.7e-159 clcA P chloride
IPEPIGIO_01045 3.5e-30 secG U Preprotein translocase
IPEPIGIO_01046 5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
IPEPIGIO_01047 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IPEPIGIO_01048 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IPEPIGIO_01049 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
IPEPIGIO_01050 1.5e-256 glnP P ABC transporter
IPEPIGIO_01051 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPEPIGIO_01052 6.1e-105 yxjI
IPEPIGIO_01053 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
IPEPIGIO_01054 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPEPIGIO_01055 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IPEPIGIO_01056 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IPEPIGIO_01057 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
IPEPIGIO_01058 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
IPEPIGIO_01059 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
IPEPIGIO_01060 5.6e-161 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IPEPIGIO_01061 6.2e-168 murB 1.3.1.98 M Cell wall formation
IPEPIGIO_01062 0.0 yjcE P Sodium proton antiporter
IPEPIGIO_01063 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
IPEPIGIO_01064 2.1e-120 S Protein of unknown function (DUF1361)
IPEPIGIO_01065 6e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPEPIGIO_01066 1.6e-129 ybbR S YbbR-like protein
IPEPIGIO_01067 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPEPIGIO_01068 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IPEPIGIO_01069 4.5e-123 yliE T EAL domain
IPEPIGIO_01070 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
IPEPIGIO_01071 3.1e-104 K Bacterial regulatory proteins, tetR family
IPEPIGIO_01072 3.5e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IPEPIGIO_01073 1.5e-52
IPEPIGIO_01074 3e-72
IPEPIGIO_01075 3e-131 1.5.1.39 C nitroreductase
IPEPIGIO_01076 8.8e-154 G Transmembrane secretion effector
IPEPIGIO_01077 3.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPEPIGIO_01078 1.5e-141
IPEPIGIO_01080 1.9e-71 spxA 1.20.4.1 P ArsC family
IPEPIGIO_01081 1.5e-33
IPEPIGIO_01082 2.5e-89 V VanZ like family
IPEPIGIO_01083 3.6e-242 EGP Major facilitator Superfamily
IPEPIGIO_01084 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IPEPIGIO_01085 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IPEPIGIO_01086 4.1e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IPEPIGIO_01087 2.5e-152 licD M LicD family
IPEPIGIO_01088 1.2e-82 K Transcriptional regulator
IPEPIGIO_01089 1.5e-19
IPEPIGIO_01090 1.2e-225 pbuG S permease
IPEPIGIO_01091 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IPEPIGIO_01092 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IPEPIGIO_01093 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IPEPIGIO_01094 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IPEPIGIO_01095 5.9e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IPEPIGIO_01096 0.0 oatA I Acyltransferase
IPEPIGIO_01097 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IPEPIGIO_01098 1.1e-68 O OsmC-like protein
IPEPIGIO_01099 2.6e-46
IPEPIGIO_01100 1.1e-251 yfnA E Amino Acid
IPEPIGIO_01101 2.5e-88
IPEPIGIO_01102 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IPEPIGIO_01103 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IPEPIGIO_01104 1.8e-19
IPEPIGIO_01105 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
IPEPIGIO_01106 1.3e-81 zur P Belongs to the Fur family
IPEPIGIO_01107 7.1e-12 3.2.1.14 GH18
IPEPIGIO_01108 4.9e-148
IPEPIGIO_01109 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IPEPIGIO_01110 3e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IPEPIGIO_01111 8e-169 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPEPIGIO_01112 3.6e-41
IPEPIGIO_01114 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPEPIGIO_01115 7.8e-149 glnH ET ABC transporter substrate-binding protein
IPEPIGIO_01116 1.6e-109 gluC P ABC transporter permease
IPEPIGIO_01117 4e-108 glnP P ABC transporter permease
IPEPIGIO_01118 4.4e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IPEPIGIO_01119 1.4e-153 K CAT RNA binding domain
IPEPIGIO_01120 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
IPEPIGIO_01121 6.1e-140 G YdjC-like protein
IPEPIGIO_01122 8.3e-246 steT E amino acid
IPEPIGIO_01123 7.4e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
IPEPIGIO_01124 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
IPEPIGIO_01125 2.8e-70 K MarR family
IPEPIGIO_01126 4.9e-210 EGP Major facilitator Superfamily
IPEPIGIO_01127 3.8e-85 S membrane transporter protein
IPEPIGIO_01128 7.1e-98 K Bacterial regulatory proteins, tetR family
IPEPIGIO_01129 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPEPIGIO_01130 2.9e-78 3.6.1.55 F NUDIX domain
IPEPIGIO_01131 1.3e-48 sugE U Multidrug resistance protein
IPEPIGIO_01132 1.2e-26
IPEPIGIO_01133 5.5e-129 pgm3 G Phosphoglycerate mutase family
IPEPIGIO_01134 4.7e-125 pgm3 G Phosphoglycerate mutase family
IPEPIGIO_01135 0.0 yjbQ P TrkA C-terminal domain protein
IPEPIGIO_01136 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
IPEPIGIO_01137 7.2e-110 dedA S SNARE associated Golgi protein
IPEPIGIO_01138 0.0 helD 3.6.4.12 L DNA helicase
IPEPIGIO_01139 5e-165 fabK 1.3.1.9 S Nitronate monooxygenase
IPEPIGIO_01140 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IPEPIGIO_01141 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IPEPIGIO_01143 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
IPEPIGIO_01145 7.6e-46 L Helix-turn-helix domain
IPEPIGIO_01146 6.9e-29 L hmm pf00665
IPEPIGIO_01147 8.9e-23 L hmm pf00665
IPEPIGIO_01148 5.7e-46
IPEPIGIO_01149 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_01150 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_01151 1.4e-40
IPEPIGIO_01152 5.9e-38
IPEPIGIO_01153 5.1e-116
IPEPIGIO_01154 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
IPEPIGIO_01155 3.7e-120 K Bacterial regulatory proteins, tetR family
IPEPIGIO_01156 1.8e-72 K Transcriptional regulator
IPEPIGIO_01157 3.5e-70
IPEPIGIO_01158 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IPEPIGIO_01159 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPEPIGIO_01160 5.8e-238 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
IPEPIGIO_01161 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IPEPIGIO_01162 1.4e-144
IPEPIGIO_01163 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
IPEPIGIO_01164 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
IPEPIGIO_01165 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IPEPIGIO_01166 3.5e-129 treR K UTRA
IPEPIGIO_01167 2.9e-42
IPEPIGIO_01168 7.3e-43 S Protein of unknown function (DUF2089)
IPEPIGIO_01169 4.3e-141 pnuC H nicotinamide mononucleotide transporter
IPEPIGIO_01170 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
IPEPIGIO_01171 2.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IPEPIGIO_01172 1.3e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IPEPIGIO_01173 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IPEPIGIO_01174 3.5e-97 yieF S NADPH-dependent FMN reductase
IPEPIGIO_01175 8.4e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
IPEPIGIO_01176 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
IPEPIGIO_01177 7.7e-62
IPEPIGIO_01178 6.2e-94
IPEPIGIO_01179 1.2e-49
IPEPIGIO_01180 6.2e-57 trxA1 O Belongs to the thioredoxin family
IPEPIGIO_01181 2.1e-73
IPEPIGIO_01182 4.7e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
IPEPIGIO_01183 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPEPIGIO_01184 0.0 mtlR K Mga helix-turn-helix domain
IPEPIGIO_01185 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
IPEPIGIO_01186 7.4e-277 pipD E Dipeptidase
IPEPIGIO_01187 4.8e-99 K Helix-turn-helix domain
IPEPIGIO_01188 1e-223 1.3.5.4 C FAD dependent oxidoreductase
IPEPIGIO_01189 2.2e-173 P Major Facilitator Superfamily
IPEPIGIO_01190 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IPEPIGIO_01191 4.7e-31 ygzD K Transcriptional
IPEPIGIO_01192 1e-69
IPEPIGIO_01193 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPEPIGIO_01194 1.4e-158 dkgB S reductase
IPEPIGIO_01195 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IPEPIGIO_01196 3.1e-101 S ABC transporter permease
IPEPIGIO_01197 5.3e-259 P ABC transporter
IPEPIGIO_01198 3.1e-116 P cobalt transport
IPEPIGIO_01199 3.9e-38 S ATPases associated with a variety of cellular activities
IPEPIGIO_01200 1.6e-138 K LysR substrate binding domain
IPEPIGIO_01201 1.9e-104 GM NAD(P)H-binding
IPEPIGIO_01202 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IPEPIGIO_01203 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
IPEPIGIO_01204 1.3e-34
IPEPIGIO_01205 6.1e-76 T Belongs to the universal stress protein A family
IPEPIGIO_01206 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IPEPIGIO_01207 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IPEPIGIO_01208 3.9e-58
IPEPIGIO_01209 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IPEPIGIO_01210 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
IPEPIGIO_01211 7.4e-102 M Protein of unknown function (DUF3737)
IPEPIGIO_01212 1.2e-194 C Aldo/keto reductase family
IPEPIGIO_01214 0.0 mdlB V ABC transporter
IPEPIGIO_01215 0.0 mdlA V ABC transporter
IPEPIGIO_01216 1.3e-246 EGP Major facilitator Superfamily
IPEPIGIO_01221 1e-197 yhgE V domain protein
IPEPIGIO_01222 1.5e-95 K Transcriptional regulator (TetR family)
IPEPIGIO_01223 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
IPEPIGIO_01224 1.7e-139 endA F DNA RNA non-specific endonuclease
IPEPIGIO_01225 6.3e-99 speG J Acetyltransferase (GNAT) domain
IPEPIGIO_01226 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
IPEPIGIO_01227 1.1e-223 S CAAX protease self-immunity
IPEPIGIO_01228 1.2e-307 ybiT S ABC transporter, ATP-binding protein
IPEPIGIO_01229 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
IPEPIGIO_01230 0.0 S Predicted membrane protein (DUF2207)
IPEPIGIO_01231 0.0 uvrA3 L excinuclease ABC
IPEPIGIO_01232 3.1e-207 EGP Major facilitator Superfamily
IPEPIGIO_01233 1.2e-171 ropB K Helix-turn-helix XRE-family like proteins
IPEPIGIO_01234 2e-233 yxiO S Vacuole effluxer Atg22 like
IPEPIGIO_01235 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
IPEPIGIO_01236 1.1e-158 I alpha/beta hydrolase fold
IPEPIGIO_01237 7e-130 treR K UTRA
IPEPIGIO_01238 2.5e-235
IPEPIGIO_01239 5.6e-39 S Cytochrome B5
IPEPIGIO_01240 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IPEPIGIO_01241 1.6e-106 2.7.7.65 T Diguanylate cyclase, GGDEF domain
IPEPIGIO_01242 1.5e-109 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_01243 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IPEPIGIO_01244 3.2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IPEPIGIO_01245 0.0 ctpA 3.6.3.54 P P-type ATPase
IPEPIGIO_01246 2.1e-213 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
IPEPIGIO_01247 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IPEPIGIO_01248 1.1e-65 lysM M LysM domain
IPEPIGIO_01249 9.6e-267 yjeM E Amino Acid
IPEPIGIO_01250 4.3e-144 K Helix-turn-helix XRE-family like proteins
IPEPIGIO_01251 7.4e-71
IPEPIGIO_01253 7.7e-163 IQ KR domain
IPEPIGIO_01254 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
IPEPIGIO_01256 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
IPEPIGIO_01257 0.0 V ABC transporter
IPEPIGIO_01258 8.6e-218 ykiI
IPEPIGIO_01259 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IPEPIGIO_01260 1.2e-73 S Psort location Cytoplasmic, score
IPEPIGIO_01261 3.3e-219 T diguanylate cyclase
IPEPIGIO_01262 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
IPEPIGIO_01263 4.2e-92
IPEPIGIO_01264 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
IPEPIGIO_01265 1.8e-54 nudA S ASCH
IPEPIGIO_01266 1.8e-107 S SdpI/YhfL protein family
IPEPIGIO_01267 6.7e-87 M Lysin motif
IPEPIGIO_01268 2.3e-65 M LysM domain
IPEPIGIO_01269 6.7e-75 K helix_turn_helix, mercury resistance
IPEPIGIO_01270 1.4e-184 1.1.1.219 GM Male sterility protein
IPEPIGIO_01271 3.1e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IPEPIGIO_01272 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPEPIGIO_01273 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IPEPIGIO_01274 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IPEPIGIO_01275 5.3e-150 dicA K Helix-turn-helix domain
IPEPIGIO_01276 3.2e-55
IPEPIGIO_01277 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
IPEPIGIO_01278 7.4e-64
IPEPIGIO_01279 0.0 P Concanavalin A-like lectin/glucanases superfamily
IPEPIGIO_01280 0.0 yhcA V ABC transporter, ATP-binding protein
IPEPIGIO_01281 1.2e-95 cadD P Cadmium resistance transporter
IPEPIGIO_01282 2e-49 K Transcriptional regulator, ArsR family
IPEPIGIO_01283 1.9e-116 S SNARE associated Golgi protein
IPEPIGIO_01284 6.1e-122 K Helix-turn-helix XRE-family like proteins
IPEPIGIO_01285 2.8e-82 gtrA S GtrA-like protein
IPEPIGIO_01286 6.6e-113 zmp3 O Zinc-dependent metalloprotease
IPEPIGIO_01287 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_01288 2.6e-65
IPEPIGIO_01289 1.7e-07 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
IPEPIGIO_01290 4.3e-84 K transcriptional regulator
IPEPIGIO_01291 1.4e-181 yfeX P Peroxidase
IPEPIGIO_01292 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IPEPIGIO_01293 6.3e-128 ydcF S Gram-negative-bacterium-type cell wall biogenesis
IPEPIGIO_01294 1.1e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IPEPIGIO_01295 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
IPEPIGIO_01296 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IPEPIGIO_01297 1.5e-55 txlA O Thioredoxin-like domain
IPEPIGIO_01298 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
IPEPIGIO_01299 1.2e-18
IPEPIGIO_01300 6.6e-96 dps P Belongs to the Dps family
IPEPIGIO_01301 1.6e-32 copZ P Heavy-metal-associated domain
IPEPIGIO_01302 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IPEPIGIO_01303 0.0 pepO 3.4.24.71 O Peptidase family M13
IPEPIGIO_01304 3.2e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IPEPIGIO_01305 1.3e-262 nox C NADH oxidase
IPEPIGIO_01306 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IPEPIGIO_01307 1e-163 S Cell surface protein
IPEPIGIO_01308 1.5e-118 S WxL domain surface cell wall-binding
IPEPIGIO_01309 2.3e-99 S WxL domain surface cell wall-binding
IPEPIGIO_01310 4.6e-45
IPEPIGIO_01311 1.7e-102 K Bacterial regulatory proteins, tetR family
IPEPIGIO_01312 1.5e-49
IPEPIGIO_01313 1.4e-248 S Putative metallopeptidase domain
IPEPIGIO_01314 3.9e-218 3.1.3.1 S associated with various cellular activities
IPEPIGIO_01315 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
IPEPIGIO_01316 0.0 ubiB S ABC1 family
IPEPIGIO_01317 4.9e-249 brnQ U Component of the transport system for branched-chain amino acids
IPEPIGIO_01318 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IPEPIGIO_01319 2.3e-229 mdtH P Sugar (and other) transporter
IPEPIGIO_01320 4.2e-305 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IPEPIGIO_01321 8.6e-232 EGP Major facilitator Superfamily
IPEPIGIO_01322 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
IPEPIGIO_01323 2.1e-38 fic D Fic/DOC family
IPEPIGIO_01324 1.9e-25 fic D Fic/DOC family
IPEPIGIO_01325 2.4e-22 fic D Fic/DOC family
IPEPIGIO_01326 8e-76 K Helix-turn-helix XRE-family like proteins
IPEPIGIO_01327 1.6e-180 galR K Transcriptional regulator
IPEPIGIO_01328 2.9e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IPEPIGIO_01329 3.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IPEPIGIO_01330 4.6e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPEPIGIO_01331 7.3e-170 lmrB EGP Major facilitator Superfamily
IPEPIGIO_01332 1.4e-117 S Domain of unknown function (DUF4811)
IPEPIGIO_01333 1e-106
IPEPIGIO_01334 4.4e-35 yyaN K MerR HTH family regulatory protein
IPEPIGIO_01335 1.7e-120 azlC E branched-chain amino acid
IPEPIGIO_01336 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
IPEPIGIO_01337 0.0 asnB 6.3.5.4 E Asparagine synthase
IPEPIGIO_01338 4.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
IPEPIGIO_01339 1.5e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPEPIGIO_01340 1e-254 xylP2 G symporter
IPEPIGIO_01341 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
IPEPIGIO_01342 5.6e-49
IPEPIGIO_01343 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IPEPIGIO_01344 2e-91 3.2.2.20 K FR47-like protein
IPEPIGIO_01345 3.4e-127 yibF S overlaps another CDS with the same product name
IPEPIGIO_01346 1.4e-218 yibE S overlaps another CDS with the same product name
IPEPIGIO_01347 3.9e-179
IPEPIGIO_01348 5.6e-138 S NADPH-dependent FMN reductase
IPEPIGIO_01349 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
IPEPIGIO_01350 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IPEPIGIO_01351 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IPEPIGIO_01352 4.1e-32 L leucine-zipper of insertion element IS481
IPEPIGIO_01353 8.5e-41
IPEPIGIO_01354 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IPEPIGIO_01355 6.7e-278 pipD E Dipeptidase
IPEPIGIO_01356 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
IPEPIGIO_01357 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IPEPIGIO_01358 1.6e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPEPIGIO_01359 2.3e-81 rmaD K Transcriptional regulator
IPEPIGIO_01361 3.4e-219 1.3.5.4 C FMN_bind
IPEPIGIO_01362 1.2e-97 1.3.5.4 C FMN_bind
IPEPIGIO_01363 2.8e-171 K Transcriptional regulator
IPEPIGIO_01364 2.3e-96 K Helix-turn-helix domain
IPEPIGIO_01365 2.3e-139 K sequence-specific DNA binding
IPEPIGIO_01366 1e-87 S AAA domain
IPEPIGIO_01368 2.6e-186 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
IPEPIGIO_01369 1e-298 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
IPEPIGIO_01370 5.5e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
IPEPIGIO_01371 1.7e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
IPEPIGIO_01372 2.7e-171 L Belongs to the 'phage' integrase family
IPEPIGIO_01373 3e-252 dtpT U amino acid peptide transporter
IPEPIGIO_01374 1.3e-150 yjjH S Calcineurin-like phosphoesterase
IPEPIGIO_01378 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
IPEPIGIO_01379 2.5e-53 S Cupin domain
IPEPIGIO_01380 1.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IPEPIGIO_01381 4.7e-194 ybiR P Citrate transporter
IPEPIGIO_01382 1.6e-151 pnuC H nicotinamide mononucleotide transporter
IPEPIGIO_01383 3.8e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPEPIGIO_01384 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IPEPIGIO_01385 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
IPEPIGIO_01386 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IPEPIGIO_01387 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IPEPIGIO_01388 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IPEPIGIO_01389 0.0 pacL 3.6.3.8 P P-type ATPase
IPEPIGIO_01390 3.4e-71
IPEPIGIO_01391 0.0 yhgF K Tex-like protein N-terminal domain protein
IPEPIGIO_01392 9.8e-82 ydcK S Belongs to the SprT family
IPEPIGIO_01393 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IPEPIGIO_01394 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IPEPIGIO_01396 1.5e-146 G Peptidase_C39 like family
IPEPIGIO_01397 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IPEPIGIO_01398 3.4e-133 manY G PTS system
IPEPIGIO_01399 4.4e-169 manN G system, mannose fructose sorbose family IID component
IPEPIGIO_01400 4.7e-64 S Domain of unknown function (DUF956)
IPEPIGIO_01401 0.0 levR K Sigma-54 interaction domain
IPEPIGIO_01402 4.3e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
IPEPIGIO_01403 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
IPEPIGIO_01404 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPEPIGIO_01405 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
IPEPIGIO_01406 4.4e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
IPEPIGIO_01407 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPEPIGIO_01408 4.3e-133 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
IPEPIGIO_01409 5.3e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IPEPIGIO_01410 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IPEPIGIO_01411 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IPEPIGIO_01412 2.4e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IPEPIGIO_01413 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
IPEPIGIO_01414 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IPEPIGIO_01415 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IPEPIGIO_01416 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IPEPIGIO_01417 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
IPEPIGIO_01418 9.1e-308 S Alpha beta
IPEPIGIO_01419 1.8e-23
IPEPIGIO_01420 3e-99 S ECF transporter, substrate-specific component
IPEPIGIO_01421 5.8e-253 yfnA E Amino Acid
IPEPIGIO_01422 1.4e-165 mleP S Sodium Bile acid symporter family
IPEPIGIO_01423 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IPEPIGIO_01424 1.2e-166 mleR K LysR family
IPEPIGIO_01425 4.9e-162 mleR K LysR family transcriptional regulator
IPEPIGIO_01426 2.7e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IPEPIGIO_01427 1.5e-261 frdC 1.3.5.4 C FAD binding domain
IPEPIGIO_01428 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IPEPIGIO_01429 3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IPEPIGIO_01430 3.7e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IPEPIGIO_01431 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
IPEPIGIO_01432 5.7e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IPEPIGIO_01433 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IPEPIGIO_01434 2.9e-179 citR K sugar-binding domain protein
IPEPIGIO_01435 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
IPEPIGIO_01436 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IPEPIGIO_01437 3.1e-50
IPEPIGIO_01438 7.9e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
IPEPIGIO_01439 8.2e-141 mtsB U ABC 3 transport family
IPEPIGIO_01440 4.5e-132 mntB 3.6.3.35 P ABC transporter
IPEPIGIO_01441 1.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IPEPIGIO_01442 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
IPEPIGIO_01443 9.9e-180 proV E ABC transporter, ATP-binding protein
IPEPIGIO_01444 4e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPEPIGIO_01445 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
IPEPIGIO_01446 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
IPEPIGIO_01447 4.5e-174 rihC 3.2.2.1 F Nucleoside
IPEPIGIO_01448 1.9e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IPEPIGIO_01449 9.3e-80
IPEPIGIO_01450 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
IPEPIGIO_01451 1.5e-230 flhF N Uncharacterized conserved protein (DUF2075)
IPEPIGIO_01452 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
IPEPIGIO_01453 1.1e-54 ypaA S Protein of unknown function (DUF1304)
IPEPIGIO_01454 4.2e-310 mco Q Multicopper oxidase
IPEPIGIO_01455 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IPEPIGIO_01456 1.9e-20 zmp1 O Zinc-dependent metalloprotease
IPEPIGIO_01457 3.7e-44
IPEPIGIO_01458 4.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IPEPIGIO_01459 4.7e-241 amtB P ammonium transporter
IPEPIGIO_01460 6e-258 P Major Facilitator Superfamily
IPEPIGIO_01461 2.8e-91 K Transcriptional regulator PadR-like family
IPEPIGIO_01462 8.4e-44
IPEPIGIO_01463 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IPEPIGIO_01464 6e-154 tagG U Transport permease protein
IPEPIGIO_01465 3.8e-218
IPEPIGIO_01466 7.8e-222 mtnE 2.6.1.83 E Aminotransferase
IPEPIGIO_01467 1.8e-61 S CHY zinc finger
IPEPIGIO_01468 2.5e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IPEPIGIO_01469 5.7e-95 bioY S BioY family
IPEPIGIO_01470 3e-40
IPEPIGIO_01471 6.5e-281 pipD E Dipeptidase
IPEPIGIO_01472 1.1e-29
IPEPIGIO_01473 8.7e-122 qmcA O prohibitin homologues
IPEPIGIO_01474 1.5e-239 xylP1 G MFS/sugar transport protein
IPEPIGIO_01476 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IPEPIGIO_01477 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
IPEPIGIO_01478 1.5e-109 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_01479 2.5e-250 malT G Major Facilitator
IPEPIGIO_01480 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IPEPIGIO_01481 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IPEPIGIO_01482 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IPEPIGIO_01483 1.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IPEPIGIO_01484 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IPEPIGIO_01485 9e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IPEPIGIO_01486 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IPEPIGIO_01487 2.1e-72 ypmB S protein conserved in bacteria
IPEPIGIO_01488 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IPEPIGIO_01489 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IPEPIGIO_01490 1.1e-127 dnaD L Replication initiation and membrane attachment
IPEPIGIO_01492 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPEPIGIO_01493 2e-99 metI P ABC transporter permease
IPEPIGIO_01494 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
IPEPIGIO_01495 4.4e-83 uspA T Universal stress protein family
IPEPIGIO_01496 2.7e-247 ftpA P Binding-protein-dependent transport system inner membrane component
IPEPIGIO_01497 1e-24 ftpA P Binding-protein-dependent transport system inner membrane component
IPEPIGIO_01498 4.9e-182 ftpB P Bacterial extracellular solute-binding protein
IPEPIGIO_01499 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
IPEPIGIO_01500 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IPEPIGIO_01501 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IPEPIGIO_01502 8.3e-110 ypsA S Belongs to the UPF0398 family
IPEPIGIO_01503 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IPEPIGIO_01505 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IPEPIGIO_01506 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
IPEPIGIO_01507 6.1e-244 P Major Facilitator Superfamily
IPEPIGIO_01508 9.9e-111 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IPEPIGIO_01509 1.7e-09 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IPEPIGIO_01510 1.7e-72 S SnoaL-like domain
IPEPIGIO_01511 2.8e-241 M Glycosyltransferase, group 2 family protein
IPEPIGIO_01512 5.1e-209 mccF V LD-carboxypeptidase
IPEPIGIO_01513 1.4e-78 K Acetyltransferase (GNAT) domain
IPEPIGIO_01514 2e-45 ygbF S Sugar efflux transporter for intercellular exchange
IPEPIGIO_01515 1.8e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IPEPIGIO_01516 0.0 rafA 3.2.1.22 G alpha-galactosidase
IPEPIGIO_01517 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
IPEPIGIO_01518 1.5e-304 scrB 3.2.1.26 GH32 G invertase
IPEPIGIO_01519 9.1e-173 scrR K Transcriptional regulator, LacI family
IPEPIGIO_01520 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IPEPIGIO_01521 1.4e-164 3.5.1.10 C nadph quinone reductase
IPEPIGIO_01522 5.9e-218 nhaC C Na H antiporter NhaC
IPEPIGIO_01523 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IPEPIGIO_01524 1.4e-127 mleR K LysR substrate binding domain
IPEPIGIO_01525 5e-27 mleR K LysR substrate binding domain
IPEPIGIO_01526 0.0 3.6.4.13 M domain protein
IPEPIGIO_01528 2.1e-157 hipB K Helix-turn-helix
IPEPIGIO_01529 0.0 oppA E ABC transporter, substratebinding protein
IPEPIGIO_01530 1.8e-309 oppA E ABC transporter, substratebinding protein
IPEPIGIO_01531 5.9e-79 yiaC K Acetyltransferase (GNAT) domain
IPEPIGIO_01532 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPEPIGIO_01533 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IPEPIGIO_01534 3e-113 pgm1 G phosphoglycerate mutase
IPEPIGIO_01535 1.1e-178 yghZ C Aldo keto reductase family protein
IPEPIGIO_01536 4.9e-34
IPEPIGIO_01537 1.3e-60 S Domain of unknown function (DU1801)
IPEPIGIO_01538 2.9e-162 FbpA K Domain of unknown function (DUF814)
IPEPIGIO_01539 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPEPIGIO_01541 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPEPIGIO_01542 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPEPIGIO_01543 8.9e-213 S ATPases associated with a variety of cellular activities
IPEPIGIO_01544 1.5e-89 S Domain of unknown function (DUF4767)
IPEPIGIO_01545 2.3e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IPEPIGIO_01546 1.2e-149 yitU 3.1.3.104 S hydrolase
IPEPIGIO_01547 1.4e-265 yfnA E Amino Acid
IPEPIGIO_01548 5.1e-259 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPEPIGIO_01549 2.4e-43
IPEPIGIO_01550 1.9e-49
IPEPIGIO_01551 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
IPEPIGIO_01552 1.4e-170 2.5.1.74 H UbiA prenyltransferase family
IPEPIGIO_01553 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IPEPIGIO_01554 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IPEPIGIO_01555 8.6e-281 pipD E Dipeptidase
IPEPIGIO_01556 9.4e-40
IPEPIGIO_01557 4.8e-29 S CsbD-like
IPEPIGIO_01558 6.5e-41 S transglycosylase associated protein
IPEPIGIO_01559 3.1e-14
IPEPIGIO_01560 2.9e-35
IPEPIGIO_01561 3.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
IPEPIGIO_01562 1e-65 S Protein of unknown function (DUF805)
IPEPIGIO_01563 2.4e-75 uspA T Belongs to the universal stress protein A family
IPEPIGIO_01564 1.9e-67 tspO T TspO/MBR family
IPEPIGIO_01565 7.9e-41
IPEPIGIO_01566 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
IPEPIGIO_01567 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
IPEPIGIO_01568 8e-33 L hmm pf00665
IPEPIGIO_01569 1.8e-207 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IPEPIGIO_01570 1.3e-28
IPEPIGIO_01571 8.5e-54
IPEPIGIO_01572 1.2e-139 f42a O Band 7 protein
IPEPIGIO_01573 1.4e-301 norB EGP Major Facilitator
IPEPIGIO_01574 7.5e-92 K transcriptional regulator
IPEPIGIO_01575 1.9e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IPEPIGIO_01576 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
IPEPIGIO_01577 1.6e-160 K LysR substrate binding domain
IPEPIGIO_01578 2.2e-123 S Protein of unknown function (DUF554)
IPEPIGIO_01579 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IPEPIGIO_01580 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IPEPIGIO_01581 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IPEPIGIO_01582 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPEPIGIO_01583 8.1e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IPEPIGIO_01584 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IPEPIGIO_01585 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IPEPIGIO_01586 1.4e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPEPIGIO_01587 2.1e-126 IQ reductase
IPEPIGIO_01588 1.3e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IPEPIGIO_01589 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPEPIGIO_01590 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPEPIGIO_01591 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IPEPIGIO_01592 1.1e-178 yneE K Transcriptional regulator
IPEPIGIO_01593 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IPEPIGIO_01595 4.7e-58 S Protein of unknown function (DUF1648)
IPEPIGIO_01596 5.1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IPEPIGIO_01597 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
IPEPIGIO_01598 5.8e-217 E glutamate:sodium symporter activity
IPEPIGIO_01599 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
IPEPIGIO_01600 4.8e-165 1.6.5.5 C Zinc-binding dehydrogenase
IPEPIGIO_01601 2e-97 entB 3.5.1.19 Q Isochorismatase family
IPEPIGIO_01602 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IPEPIGIO_01603 3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IPEPIGIO_01604 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IPEPIGIO_01605 1.4e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IPEPIGIO_01606 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPEPIGIO_01607 7.2e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
IPEPIGIO_01608 2.4e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
IPEPIGIO_01609 9.9e-270 XK27_00765
IPEPIGIO_01610 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
IPEPIGIO_01611 5.3e-86
IPEPIGIO_01612 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
IPEPIGIO_01613 6.8e-53
IPEPIGIO_01614 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IPEPIGIO_01615 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IPEPIGIO_01616 1.4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPEPIGIO_01617 2.6e-39 ylqC S Belongs to the UPF0109 family
IPEPIGIO_01618 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IPEPIGIO_01619 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPEPIGIO_01620 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IPEPIGIO_01621 1.9e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IPEPIGIO_01622 0.0 smc D Required for chromosome condensation and partitioning
IPEPIGIO_01623 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IPEPIGIO_01624 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPEPIGIO_01625 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IPEPIGIO_01626 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPEPIGIO_01627 0.0 yloV S DAK2 domain fusion protein YloV
IPEPIGIO_01628 1.8e-57 asp S Asp23 family, cell envelope-related function
IPEPIGIO_01629 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IPEPIGIO_01630 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
IPEPIGIO_01631 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IPEPIGIO_01632 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IPEPIGIO_01633 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IPEPIGIO_01634 1.7e-134 stp 3.1.3.16 T phosphatase
IPEPIGIO_01635 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IPEPIGIO_01636 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPEPIGIO_01637 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPEPIGIO_01638 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IPEPIGIO_01639 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IPEPIGIO_01640 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IPEPIGIO_01641 4.5e-55
IPEPIGIO_01642 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
IPEPIGIO_01643 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPEPIGIO_01644 1.2e-104 opuCB E ABC transporter permease
IPEPIGIO_01645 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
IPEPIGIO_01646 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
IPEPIGIO_01647 2.2e-76 argR K Regulates arginine biosynthesis genes
IPEPIGIO_01648 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IPEPIGIO_01649 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IPEPIGIO_01650 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPEPIGIO_01651 7.9e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPEPIGIO_01652 1.1e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPEPIGIO_01653 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPEPIGIO_01654 3.5e-74 yqhY S Asp23 family, cell envelope-related function
IPEPIGIO_01655 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPEPIGIO_01656 5.9e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IPEPIGIO_01657 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IPEPIGIO_01658 3.2e-53 ysxB J Cysteine protease Prp
IPEPIGIO_01659 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IPEPIGIO_01660 1.8e-89 K Transcriptional regulator
IPEPIGIO_01661 5.4e-19
IPEPIGIO_01664 1.7e-30
IPEPIGIO_01665 5.3e-56
IPEPIGIO_01666 2.4e-98 dut S Protein conserved in bacteria
IPEPIGIO_01667 4e-181
IPEPIGIO_01668 2e-161
IPEPIGIO_01669 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
IPEPIGIO_01670 8.6e-63 glnR K Transcriptional regulator
IPEPIGIO_01671 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPEPIGIO_01672 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
IPEPIGIO_01673 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
IPEPIGIO_01674 4.4e-68 yqhL P Rhodanese-like protein
IPEPIGIO_01675 6.4e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
IPEPIGIO_01676 1.7e-179 glk 2.7.1.2 G Glucokinase
IPEPIGIO_01677 7.1e-33 yqgQ S Bacterial protein of unknown function (DUF910)
IPEPIGIO_01678 3e-114 gluP 3.4.21.105 S Peptidase, S54 family
IPEPIGIO_01679 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPEPIGIO_01680 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IPEPIGIO_01681 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IPEPIGIO_01682 0.0 S membrane
IPEPIGIO_01683 1.5e-54 yneR S Belongs to the HesB IscA family
IPEPIGIO_01684 4e-75 XK27_02470 K LytTr DNA-binding domain
IPEPIGIO_01685 2.3e-96 liaI S membrane
IPEPIGIO_01686 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPEPIGIO_01687 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
IPEPIGIO_01688 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPEPIGIO_01689 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPEPIGIO_01690 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPEPIGIO_01691 1.1e-62 yodB K Transcriptional regulator, HxlR family
IPEPIGIO_01692 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IPEPIGIO_01693 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPEPIGIO_01694 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IPEPIGIO_01695 5.9e-150 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPEPIGIO_01696 9.3e-93 S SdpI/YhfL protein family
IPEPIGIO_01697 1.7e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IPEPIGIO_01698 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IPEPIGIO_01699 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IPEPIGIO_01700 8e-307 arlS 2.7.13.3 T Histidine kinase
IPEPIGIO_01701 4.3e-121 K response regulator
IPEPIGIO_01702 4.2e-245 rarA L recombination factor protein RarA
IPEPIGIO_01703 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPEPIGIO_01704 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPEPIGIO_01705 7e-88 S Peptidase propeptide and YPEB domain
IPEPIGIO_01706 1.6e-97 yceD S Uncharacterized ACR, COG1399
IPEPIGIO_01707 7.5e-219 ylbM S Belongs to the UPF0348 family
IPEPIGIO_01708 4.4e-140 yqeM Q Methyltransferase
IPEPIGIO_01709 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IPEPIGIO_01710 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IPEPIGIO_01711 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPEPIGIO_01712 1.1e-50 yhbY J RNA-binding protein
IPEPIGIO_01713 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
IPEPIGIO_01714 1.4e-98 yqeG S HAD phosphatase, family IIIA
IPEPIGIO_01715 1.3e-79
IPEPIGIO_01716 1e-248 pgaC GT2 M Glycosyl transferase
IPEPIGIO_01717 5e-41 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IPEPIGIO_01718 1e-84 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IPEPIGIO_01719 1e-62 hxlR K Transcriptional regulator, HxlR family
IPEPIGIO_01720 7.5e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IPEPIGIO_01721 5e-240 yrvN L AAA C-terminal domain
IPEPIGIO_01722 1.1e-55
IPEPIGIO_01723 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPEPIGIO_01724 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IPEPIGIO_01725 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPEPIGIO_01726 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPEPIGIO_01727 1.2e-171 dnaI L Primosomal protein DnaI
IPEPIGIO_01728 1.1e-248 dnaB L replication initiation and membrane attachment
IPEPIGIO_01729 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPEPIGIO_01730 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IPEPIGIO_01731 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IPEPIGIO_01732 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPEPIGIO_01733 4.5e-121 ybhL S Belongs to the BI1 family
IPEPIGIO_01734 3.1e-111 hipB K Helix-turn-helix
IPEPIGIO_01735 5.5e-45 yitW S Iron-sulfur cluster assembly protein
IPEPIGIO_01736 1.4e-272 sufB O assembly protein SufB
IPEPIGIO_01737 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
IPEPIGIO_01738 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPEPIGIO_01739 2.6e-244 sufD O FeS assembly protein SufD
IPEPIGIO_01740 4.2e-144 sufC O FeS assembly ATPase SufC
IPEPIGIO_01741 1.3e-34 feoA P FeoA domain
IPEPIGIO_01742 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IPEPIGIO_01743 7.9e-21 S Virus attachment protein p12 family
IPEPIGIO_01744 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IPEPIGIO_01745 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IPEPIGIO_01746 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPEPIGIO_01747 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
IPEPIGIO_01748 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IPEPIGIO_01749 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
IPEPIGIO_01750 6.2e-224 ecsB U ABC transporter
IPEPIGIO_01751 1.6e-134 ecsA V ABC transporter, ATP-binding protein
IPEPIGIO_01752 9.9e-82 hit FG histidine triad
IPEPIGIO_01753 2e-42
IPEPIGIO_01754 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IPEPIGIO_01755 7.8e-121 draG 3.2.2.24 O ADP-ribosylglycohydrolase
IPEPIGIO_01756 3.5e-78 S WxL domain surface cell wall-binding
IPEPIGIO_01757 4e-103 S WxL domain surface cell wall-binding
IPEPIGIO_01758 9.3e-192 S Fn3-like domain
IPEPIGIO_01759 3.5e-61
IPEPIGIO_01760 0.0
IPEPIGIO_01761 2.1e-241 npr 1.11.1.1 C NADH oxidase
IPEPIGIO_01762 3.3e-112 K Bacterial regulatory proteins, tetR family
IPEPIGIO_01763 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IPEPIGIO_01764 1.6e-105
IPEPIGIO_01765 9.3e-106 GBS0088 S Nucleotidyltransferase
IPEPIGIO_01766 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IPEPIGIO_01767 3.1e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IPEPIGIO_01768 6.3e-75 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IPEPIGIO_01769 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IPEPIGIO_01770 0.0 S membrane
IPEPIGIO_01771 1.7e-19 S NUDIX domain
IPEPIGIO_01772 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPEPIGIO_01773 1.7e-15 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPEPIGIO_01774 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
IPEPIGIO_01775 2.9e-238 M hydrolase, family 25
IPEPIGIO_01776 1.3e-179 mccF 3.4.17.13 V LD-carboxypeptidase
IPEPIGIO_01777 1.3e-123
IPEPIGIO_01778 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
IPEPIGIO_01779 2.3e-193
IPEPIGIO_01780 4.2e-21 S hydrolase activity, acting on ester bonds
IPEPIGIO_01781 9.2e-104 S hydrolase activity, acting on ester bonds
IPEPIGIO_01782 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
IPEPIGIO_01783 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
IPEPIGIO_01784 2.2e-61 esbA S Family of unknown function (DUF5322)
IPEPIGIO_01785 2.3e-293 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IPEPIGIO_01786 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPEPIGIO_01787 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IPEPIGIO_01788 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPEPIGIO_01789 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
IPEPIGIO_01790 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IPEPIGIO_01791 6.4e-113 pgm5 G Phosphoglycerate mutase family
IPEPIGIO_01792 3.1e-71 frataxin S Domain of unknown function (DU1801)
IPEPIGIO_01794 1.7e-130 cat 2.3.1.28 V Chloramphenicol acetyltransferase
IPEPIGIO_01795 1.2e-69 S LuxR family transcriptional regulator
IPEPIGIO_01796 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
IPEPIGIO_01798 3e-92 3.6.1.55 F NUDIX domain
IPEPIGIO_01799 5.4e-164 V ABC transporter, ATP-binding protein
IPEPIGIO_01800 9.3e-133 S ABC-2 family transporter protein
IPEPIGIO_01801 0.0 FbpA K Fibronectin-binding protein
IPEPIGIO_01802 7.1e-66 K Transcriptional regulator
IPEPIGIO_01803 2.1e-160 degV S EDD domain protein, DegV family
IPEPIGIO_01804 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IPEPIGIO_01805 2.9e-131 S Protein of unknown function (DUF975)
IPEPIGIO_01806 1.6e-09
IPEPIGIO_01807 5.4e-49
IPEPIGIO_01808 9.6e-149 2.7.7.12 C Domain of unknown function (DUF4931)
IPEPIGIO_01809 2.7e-211 pmrB EGP Major facilitator Superfamily
IPEPIGIO_01810 4.6e-12
IPEPIGIO_01811 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
IPEPIGIO_01812 4.6e-129 yejC S Protein of unknown function (DUF1003)
IPEPIGIO_01813 3.7e-130 XK27_00890 S Domain of unknown function (DUF368)
IPEPIGIO_01814 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IPEPIGIO_01815 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
IPEPIGIO_01816 1.1e-225 patA 2.6.1.1 E Aminotransferase
IPEPIGIO_01817 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IPEPIGIO_01818 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPEPIGIO_01819 3.4e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
IPEPIGIO_01820 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IPEPIGIO_01821 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPEPIGIO_01822 2.7e-39 ptsH G phosphocarrier protein HPR
IPEPIGIO_01823 6.5e-30
IPEPIGIO_01824 0.0 clpE O Belongs to the ClpA ClpB family
IPEPIGIO_01825 1.6e-73 L Integrase
IPEPIGIO_01826 1e-63 K Winged helix DNA-binding domain
IPEPIGIO_01827 1.8e-181 oppF P Belongs to the ABC transporter superfamily
IPEPIGIO_01828 9.2e-203 oppD P Belongs to the ABC transporter superfamily
IPEPIGIO_01829 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPEPIGIO_01830 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPEPIGIO_01831 1.3e-309 oppA E ABC transporter, substratebinding protein
IPEPIGIO_01832 3.2e-57 ywjH S Protein of unknown function (DUF1634)
IPEPIGIO_01833 5.5e-126 yxaA S membrane transporter protein
IPEPIGIO_01834 7.1e-161 lysR5 K LysR substrate binding domain
IPEPIGIO_01835 8e-196 M MucBP domain
IPEPIGIO_01836 2.8e-243
IPEPIGIO_01837 4.1e-18
IPEPIGIO_01838 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IPEPIGIO_01839 8.3e-254 gor 1.8.1.7 C Glutathione reductase
IPEPIGIO_01840 1.1e-105
IPEPIGIO_01841 0.0 K PRD domain
IPEPIGIO_01842 2.4e-62 S Domain of unknown function (DUF3284)
IPEPIGIO_01843 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IPEPIGIO_01844 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IPEPIGIO_01845 8.4e-214 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPEPIGIO_01846 5.2e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IPEPIGIO_01847 9.5e-209 EGP Major facilitator Superfamily
IPEPIGIO_01848 1.3e-53 M ErfK YbiS YcfS YnhG
IPEPIGIO_01849 4.9e-41 M ErfK YbiS YcfS YnhG
IPEPIGIO_01850 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPEPIGIO_01851 5.8e-79 ydfD K Alanine-glyoxylate amino-transferase
IPEPIGIO_01852 2.3e-162 ydfD K Alanine-glyoxylate amino-transferase
IPEPIGIO_01853 1.4e-102 argO S LysE type translocator
IPEPIGIO_01854 7.1e-214 arcT 2.6.1.1 E Aminotransferase
IPEPIGIO_01855 4.4e-77 argR K Regulates arginine biosynthesis genes
IPEPIGIO_01856 2.9e-12
IPEPIGIO_01857 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IPEPIGIO_01858 1e-54 yheA S Belongs to the UPF0342 family
IPEPIGIO_01859 1.7e-232 yhaO L Ser Thr phosphatase family protein
IPEPIGIO_01860 0.0 L AAA domain
IPEPIGIO_01861 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
IPEPIGIO_01862 2.1e-213
IPEPIGIO_01863 3.1e-181 3.4.21.102 M Peptidase family S41
IPEPIGIO_01864 8.5e-176 K LysR substrate binding domain
IPEPIGIO_01865 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
IPEPIGIO_01866 0.0 1.3.5.4 C FAD binding domain
IPEPIGIO_01867 1.7e-99
IPEPIGIO_01868 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
IPEPIGIO_01869 1.9e-125 S CAAX protease self-immunity
IPEPIGIO_01870 2.4e-22 plnF
IPEPIGIO_01871 5.5e-13
IPEPIGIO_01872 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IPEPIGIO_01873 4.9e-241 mesE M Transport protein ComB
IPEPIGIO_01874 1.4e-108 S CAAX protease self-immunity
IPEPIGIO_01875 7.4e-118 ypbD S CAAX protease self-immunity
IPEPIGIO_01876 1.2e-110 V CAAX protease self-immunity
IPEPIGIO_01877 1.1e-113 S CAAX protease self-immunity
IPEPIGIO_01878 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
IPEPIGIO_01879 0.0 helD 3.6.4.12 L DNA helicase
IPEPIGIO_01880 2.1e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IPEPIGIO_01881 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IPEPIGIO_01882 9e-130 K UbiC transcription regulator-associated domain protein
IPEPIGIO_01883 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPEPIGIO_01884 3.9e-24
IPEPIGIO_01885 1.9e-74 S Domain of unknown function (DUF3284)
IPEPIGIO_01886 4.8e-34
IPEPIGIO_01887 2.8e-58 chpA T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IPEPIGIO_01888 4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPEPIGIO_01889 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IPEPIGIO_01890 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IPEPIGIO_01891 2.7e-177
IPEPIGIO_01892 3.9e-133 cobB K SIR2 family
IPEPIGIO_01893 2e-160 yunF F Protein of unknown function DUF72
IPEPIGIO_01894 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
IPEPIGIO_01895 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPEPIGIO_01896 2e-214 bcr1 EGP Major facilitator Superfamily
IPEPIGIO_01897 1.3e-83 mutR K sequence-specific DNA binding
IPEPIGIO_01899 1.7e-52 M Lysin motif
IPEPIGIO_01900 4.5e-121 S CAAX protease self-immunity
IPEPIGIO_01901 2.5e-114 V CAAX protease self-immunity
IPEPIGIO_01902 7.1e-121 yclH V ABC transporter
IPEPIGIO_01903 2.9e-183 yclI V MacB-like periplasmic core domain
IPEPIGIO_01904 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IPEPIGIO_01905 1.1e-106 tag 3.2.2.20 L glycosylase
IPEPIGIO_01906 0.0 ydgH S MMPL family
IPEPIGIO_01907 3.1e-104 K transcriptional regulator
IPEPIGIO_01908 2.7e-123 2.7.6.5 S RelA SpoT domain protein
IPEPIGIO_01909 1.3e-47
IPEPIGIO_01910 1.1e-256 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
IPEPIGIO_01911 3.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IPEPIGIO_01912 2.1e-41
IPEPIGIO_01913 9.9e-57
IPEPIGIO_01914 1.7e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPEPIGIO_01915 2.7e-129 yidA K Helix-turn-helix domain, rpiR family
IPEPIGIO_01916 4.1e-49
IPEPIGIO_01917 7e-127 K Transcriptional regulatory protein, C terminal
IPEPIGIO_01918 9.8e-250 T PhoQ Sensor
IPEPIGIO_01919 3.3e-65 K helix_turn_helix, mercury resistance
IPEPIGIO_01920 1.5e-212 ydiC1 EGP Major facilitator Superfamily
IPEPIGIO_01921 3.4e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IPEPIGIO_01922 4.3e-144 yxeH S hydrolase
IPEPIGIO_01923 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPEPIGIO_01924 8.3e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPEPIGIO_01925 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IPEPIGIO_01926 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
IPEPIGIO_01927 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPEPIGIO_01928 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPEPIGIO_01929 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
IPEPIGIO_01930 2.3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
IPEPIGIO_01931 1.1e-231 gatC G PTS system sugar-specific permease component
IPEPIGIO_01932 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IPEPIGIO_01933 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPEPIGIO_01934 7e-112 K DeoR C terminal sensor domain
IPEPIGIO_01935 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IPEPIGIO_01936 7.4e-136 K Helix-turn-helix domain, rpiR family
IPEPIGIO_01937 3.7e-72 yueI S Protein of unknown function (DUF1694)
IPEPIGIO_01938 2.9e-164 I alpha/beta hydrolase fold
IPEPIGIO_01939 1.3e-159 I alpha/beta hydrolase fold
IPEPIGIO_01940 1.7e-271 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPEPIGIO_01941 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPEPIGIO_01942 1.6e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
IPEPIGIO_01943 5.4e-153 nanK GK ROK family
IPEPIGIO_01944 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
IPEPIGIO_01956 5.5e-08
IPEPIGIO_01966 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IPEPIGIO_01967 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
IPEPIGIO_01968 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IPEPIGIO_01969 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IPEPIGIO_01970 2e-13 coiA 3.6.4.12 S Competence protein
IPEPIGIO_01971 2e-180 coiA 3.6.4.12 S Competence protein
IPEPIGIO_01972 0.0 pepF E oligoendopeptidase F
IPEPIGIO_01973 8.9e-113 yjbH Q Thioredoxin
IPEPIGIO_01974 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
IPEPIGIO_01975 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPEPIGIO_01976 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IPEPIGIO_01977 1.1e-115 cutC P Participates in the control of copper homeostasis
IPEPIGIO_01978 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IPEPIGIO_01979 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IPEPIGIO_01980 4.3e-206 XK27_05220 S AI-2E family transporter
IPEPIGIO_01981 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPEPIGIO_01982 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
IPEPIGIO_01984 4.8e-209 brnQ U Component of the transport system for branched-chain amino acids
IPEPIGIO_01985 2.4e-113 ywnB S NAD(P)H-binding
IPEPIGIO_01986 1.4e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IPEPIGIO_01987 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IPEPIGIO_01988 7e-40
IPEPIGIO_01990 1.3e-249 EGP Major facilitator Superfamily
IPEPIGIO_01991 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
IPEPIGIO_01992 4.7e-83 cvpA S Colicin V production protein
IPEPIGIO_01993 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IPEPIGIO_01994 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IPEPIGIO_01995 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IPEPIGIO_01996 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IPEPIGIO_01997 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IPEPIGIO_01998 2.3e-212 folP 2.5.1.15 H dihydropteroate synthase
IPEPIGIO_01999 6.5e-96 tag 3.2.2.20 L glycosylase
IPEPIGIO_02000 2.6e-19
IPEPIGIO_02001 2.7e-160 czcD P cation diffusion facilitator family transporter
IPEPIGIO_02002 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
IPEPIGIO_02003 3e-116 hly S protein, hemolysin III
IPEPIGIO_02004 1.1e-44 qacH U Small Multidrug Resistance protein
IPEPIGIO_02005 5.8e-59 qacC P Small Multidrug Resistance protein
IPEPIGIO_02006 1.3e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IPEPIGIO_02007 5.3e-179 K AI-2E family transporter
IPEPIGIO_02008 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPEPIGIO_02009 0.0 kup P Transport of potassium into the cell
IPEPIGIO_02011 2.3e-257 yhdG E C-terminus of AA_permease
IPEPIGIO_02012 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPEPIGIO_02013 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
IPEPIGIO_02014 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IPEPIGIO_02015 5.1e-238 M domain protein
IPEPIGIO_02016 5.1e-52 U domain, Protein
IPEPIGIO_02017 4.4e-25 S Immunity protein 74
IPEPIGIO_02018 4.8e-176
IPEPIGIO_02019 8.1e-08 S Immunity protein 22
IPEPIGIO_02020 1.3e-99 ankB S ankyrin repeats
IPEPIGIO_02021 3.3e-29
IPEPIGIO_02022 4.8e-20
IPEPIGIO_02023 2.8e-47 U nuclease activity
IPEPIGIO_02024 4.8e-69
IPEPIGIO_02025 1.1e-21
IPEPIGIO_02026 1.1e-07
IPEPIGIO_02027 4.2e-16
IPEPIGIO_02028 1.4e-61
IPEPIGIO_02029 6.1e-19 S Barstar (barnase inhibitor)
IPEPIGIO_02030 3.6e-119 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IPEPIGIO_02031 1.1e-196 uhpT EGP Major facilitator Superfamily
IPEPIGIO_02032 3.4e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
IPEPIGIO_02033 1.2e-165 K Transcriptional regulator
IPEPIGIO_02034 1.3e-148 S hydrolase
IPEPIGIO_02035 2.1e-88 brnQ U Component of the transport system for branched-chain amino acids
IPEPIGIO_02036 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02037 6.2e-29 lytE M LysM domain protein
IPEPIGIO_02038 7.4e-67 gcvH E Glycine cleavage H-protein
IPEPIGIO_02039 2.8e-176 sepS16B
IPEPIGIO_02040 1.8e-130
IPEPIGIO_02041 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
IPEPIGIO_02042 6.8e-57
IPEPIGIO_02043 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPEPIGIO_02044 4.9e-24 elaA S GNAT family
IPEPIGIO_02045 1.7e-75 K Transcriptional regulator
IPEPIGIO_02046 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
IPEPIGIO_02047 4.3e-40
IPEPIGIO_02048 4.4e-205 potD P ABC transporter
IPEPIGIO_02049 2.9e-140 potC P ABC transporter permease
IPEPIGIO_02050 4.5e-149 potB P ABC transporter permease
IPEPIGIO_02051 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IPEPIGIO_02052 1.3e-96 puuR K Cupin domain
IPEPIGIO_02053 1.1e-83 6.3.3.2 S ASCH
IPEPIGIO_02054 1e-84 K GNAT family
IPEPIGIO_02055 8e-91 K acetyltransferase
IPEPIGIO_02056 8.1e-22
IPEPIGIO_02057 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
IPEPIGIO_02058 2e-163 ytrB V ABC transporter
IPEPIGIO_02060 3.9e-162 K Transcriptional regulator
IPEPIGIO_02061 1.1e-161 akr5f 1.1.1.346 S reductase
IPEPIGIO_02062 1.4e-164 S Oxidoreductase, aldo keto reductase family protein
IPEPIGIO_02063 3e-78 K Winged helix DNA-binding domain
IPEPIGIO_02064 6.4e-268 ycaM E amino acid
IPEPIGIO_02065 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
IPEPIGIO_02066 2.7e-32
IPEPIGIO_02067 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
IPEPIGIO_02068 0.0 M Bacterial Ig-like domain (group 3)
IPEPIGIO_02069 4.2e-77 fld C Flavodoxin
IPEPIGIO_02070 1.3e-216
IPEPIGIO_02071 1.3e-99 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IPEPIGIO_02072 1.9e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IPEPIGIO_02073 1.4e-151 EG EamA-like transporter family
IPEPIGIO_02074 2.3e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPEPIGIO_02075 9.8e-152 S hydrolase
IPEPIGIO_02076 1.8e-81
IPEPIGIO_02077 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IPEPIGIO_02078 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
IPEPIGIO_02079 9.9e-129 gntR K UTRA
IPEPIGIO_02080 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IPEPIGIO_02081 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
IPEPIGIO_02082 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IPEPIGIO_02083 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IPEPIGIO_02084 1.7e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IPEPIGIO_02085 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
IPEPIGIO_02086 1.1e-151 V ABC transporter
IPEPIGIO_02087 2.8e-117 K Transcriptional regulator
IPEPIGIO_02088 4.3e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IPEPIGIO_02089 3.6e-88 niaR S 3H domain
IPEPIGIO_02090 2.1e-232 S Sterol carrier protein domain
IPEPIGIO_02091 1.4e-211 S Bacterial protein of unknown function (DUF871)
IPEPIGIO_02092 1.2e-35 XK27_01315 S Protein of unknown function (DUF2829)
IPEPIGIO_02093 1.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
IPEPIGIO_02094 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
IPEPIGIO_02095 7.5e-103 3.6.1.13 L Belongs to the Nudix hydrolase family
IPEPIGIO_02096 9.3e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IPEPIGIO_02097 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
IPEPIGIO_02098 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
IPEPIGIO_02099 1.1e-281 thrC 4.2.3.1 E Threonine synthase
IPEPIGIO_02100 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IPEPIGIO_02102 1.5e-52
IPEPIGIO_02103 5.4e-118
IPEPIGIO_02104 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
IPEPIGIO_02105 6.6e-234 malY 4.4.1.8 E Aminotransferase, class I
IPEPIGIO_02107 3.2e-50
IPEPIGIO_02108 1.1e-88
IPEPIGIO_02109 5.5e-71 gtcA S Teichoic acid glycosylation protein
IPEPIGIO_02110 4e-34
IPEPIGIO_02111 1.9e-80 uspA T universal stress protein
IPEPIGIO_02112 5.1e-137
IPEPIGIO_02113 5.8e-163 V ABC transporter, ATP-binding protein
IPEPIGIO_02114 7.9e-61 gntR1 K Transcriptional regulator, GntR family
IPEPIGIO_02115 2.2e-39
IPEPIGIO_02116 0.0 V FtsX-like permease family
IPEPIGIO_02117 1.7e-139 cysA V ABC transporter, ATP-binding protein
IPEPIGIO_02118 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
IPEPIGIO_02119 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_02120 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
IPEPIGIO_02121 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
IPEPIGIO_02122 3.2e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
IPEPIGIO_02123 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
IPEPIGIO_02124 4.3e-223 XK27_09615 1.3.5.4 S reductase
IPEPIGIO_02125 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IPEPIGIO_02126 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IPEPIGIO_02127 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IPEPIGIO_02128 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPEPIGIO_02129 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPEPIGIO_02130 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPEPIGIO_02131 2.1e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPEPIGIO_02132 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IPEPIGIO_02133 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IPEPIGIO_02134 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IPEPIGIO_02135 2.1e-214 purD 6.3.4.13 F Belongs to the GARS family
IPEPIGIO_02136 1e-122 2.1.1.14 E Methionine synthase
IPEPIGIO_02137 9.2e-253 pgaC GT2 M Glycosyl transferase
IPEPIGIO_02138 2.6e-94
IPEPIGIO_02139 6.5e-156 T EAL domain
IPEPIGIO_02140 5.6e-161 GM NmrA-like family
IPEPIGIO_02141 2.4e-221 pbuG S Permease family
IPEPIGIO_02142 2.7e-236 pbuX F xanthine permease
IPEPIGIO_02143 1e-298 pucR QT Purine catabolism regulatory protein-like family
IPEPIGIO_02144 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPEPIGIO_02145 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IPEPIGIO_02146 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IPEPIGIO_02147 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IPEPIGIO_02148 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IPEPIGIO_02149 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IPEPIGIO_02150 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IPEPIGIO_02151 2.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPEPIGIO_02152 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
IPEPIGIO_02153 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IPEPIGIO_02154 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IPEPIGIO_02155 8.2e-96 wecD K Acetyltransferase (GNAT) family
IPEPIGIO_02156 5.6e-115 ylbE GM NAD(P)H-binding
IPEPIGIO_02157 1.9e-161 mleR K LysR family
IPEPIGIO_02158 1.7e-126 S membrane transporter protein
IPEPIGIO_02159 3e-18
IPEPIGIO_02160 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPEPIGIO_02161 8.5e-218 patA 2.6.1.1 E Aminotransferase
IPEPIGIO_02162 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
IPEPIGIO_02163 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPEPIGIO_02164 8.5e-57 S SdpI/YhfL protein family
IPEPIGIO_02165 1.9e-127 C Zinc-binding dehydrogenase
IPEPIGIO_02166 3e-30 C Zinc-binding dehydrogenase
IPEPIGIO_02167 5e-63 K helix_turn_helix, mercury resistance
IPEPIGIO_02168 2.8e-213 yttB EGP Major facilitator Superfamily
IPEPIGIO_02169 2.9e-269 yjcE P Sodium proton antiporter
IPEPIGIO_02170 4.9e-87 nrdI F Belongs to the NrdI family
IPEPIGIO_02171 1.2e-239 yhdP S Transporter associated domain
IPEPIGIO_02172 4.4e-58
IPEPIGIO_02173 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
IPEPIGIO_02174 7.7e-61
IPEPIGIO_02175 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
IPEPIGIO_02176 5.5e-138 rrp8 K LytTr DNA-binding domain
IPEPIGIO_02177 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IPEPIGIO_02178 1.5e-138
IPEPIGIO_02179 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IPEPIGIO_02180 2.4e-130 gntR2 K Transcriptional regulator
IPEPIGIO_02181 2.3e-164 S Putative esterase
IPEPIGIO_02182 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IPEPIGIO_02183 2.3e-223 lsgC M Glycosyl transferases group 1
IPEPIGIO_02184 3.3e-21 S Protein of unknown function (DUF2929)
IPEPIGIO_02185 1.7e-48 K Cro/C1-type HTH DNA-binding domain
IPEPIGIO_02186 1.3e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IPEPIGIO_02187 1.6e-79 uspA T universal stress protein
IPEPIGIO_02188 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
IPEPIGIO_02189 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
IPEPIGIO_02190 4e-60
IPEPIGIO_02191 3.7e-73
IPEPIGIO_02192 5e-82 yybC S Protein of unknown function (DUF2798)
IPEPIGIO_02193 1.7e-45
IPEPIGIO_02194 5.2e-47
IPEPIGIO_02195 1.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IPEPIGIO_02196 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
IPEPIGIO_02197 8.4e-145 yjfP S Dienelactone hydrolase family
IPEPIGIO_02198 9.8e-28
IPEPIGIO_02199 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IPEPIGIO_02200 6.5e-47
IPEPIGIO_02201 1.3e-57
IPEPIGIO_02202 2.3e-164
IPEPIGIO_02203 1.3e-72 K Transcriptional regulator
IPEPIGIO_02204 0.0 pepF2 E Oligopeptidase F
IPEPIGIO_02205 3.8e-173 D Alpha beta
IPEPIGIO_02206 1.8e-44 S Enterocin A Immunity
IPEPIGIO_02207 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
IPEPIGIO_02208 8.7e-125 skfE V ABC transporter
IPEPIGIO_02209 2.7e-132
IPEPIGIO_02210 3.7e-107 pncA Q Isochorismatase family
IPEPIGIO_02211 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPEPIGIO_02212 0.0 yjcE P Sodium proton antiporter
IPEPIGIO_02213 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
IPEPIGIO_02214 5.1e-176 S Oxidoreductase family, NAD-binding Rossmann fold
IPEPIGIO_02215 1.1e-116 K Helix-turn-helix domain, rpiR family
IPEPIGIO_02216 2.3e-157 ccpB 5.1.1.1 K lacI family
IPEPIGIO_02217 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
IPEPIGIO_02218 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPEPIGIO_02219 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
IPEPIGIO_02220 1.2e-97 drgA C Nitroreductase family
IPEPIGIO_02221 3.6e-168 S Polyphosphate kinase 2 (PPK2)
IPEPIGIO_02222 6.2e-182 3.6.4.13 S domain, Protein
IPEPIGIO_02223 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_02224 8.9e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IPEPIGIO_02225 1.2e-134 K UTRA domain
IPEPIGIO_02226 3.4e-154 estA S Putative esterase
IPEPIGIO_02227 1e-63
IPEPIGIO_02228 1.8e-210 ydiN G Major Facilitator Superfamily
IPEPIGIO_02229 3.4e-163 K Transcriptional regulator, LysR family
IPEPIGIO_02230 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPEPIGIO_02231 2.7e-214 ydiM G Transporter
IPEPIGIO_02232 2.1e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IPEPIGIO_02233 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IPEPIGIO_02234 0.0 1.3.5.4 C FAD binding domain
IPEPIGIO_02235 5.2e-65 S pyridoxamine 5-phosphate
IPEPIGIO_02236 8.2e-193 C Aldo keto reductase family protein
IPEPIGIO_02237 1.1e-173 galR K Transcriptional regulator
IPEPIGIO_02238 4.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IPEPIGIO_02239 0.0 lacS G Transporter
IPEPIGIO_02240 0.0 rafA 3.2.1.22 G alpha-galactosidase
IPEPIGIO_02241 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
IPEPIGIO_02242 1.3e-66 S Iron-sulphur cluster biosynthesis
IPEPIGIO_02243 2.3e-113 S GyrI-like small molecule binding domain
IPEPIGIO_02244 2.4e-187 S Cell surface protein
IPEPIGIO_02245 2.2e-100 S WxL domain surface cell wall-binding
IPEPIGIO_02246 1.1e-62
IPEPIGIO_02247 2.9e-208 NU Mycoplasma protein of unknown function, DUF285
IPEPIGIO_02248 5.9e-117
IPEPIGIO_02249 1e-116 S Haloacid dehalogenase-like hydrolase
IPEPIGIO_02250 2e-61 K Transcriptional regulator, HxlR family
IPEPIGIO_02251 5.1e-210 ytbD EGP Major facilitator Superfamily
IPEPIGIO_02252 1.4e-94 M ErfK YbiS YcfS YnhG
IPEPIGIO_02253 0.0 asnB 6.3.5.4 E Asparagine synthase
IPEPIGIO_02254 1.7e-134 K LytTr DNA-binding domain
IPEPIGIO_02255 1.3e-203 2.7.13.3 T GHKL domain
IPEPIGIO_02256 1.5e-95 fadR K Bacterial regulatory proteins, tetR family
IPEPIGIO_02257 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02258 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02259 1.6e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IPEPIGIO_02260 1.5e-272 hsdM 2.1.1.72 V type I restriction-modification system
IPEPIGIO_02261 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IPEPIGIO_02262 0.0 pepN 3.4.11.2 E aminopeptidase
IPEPIGIO_02263 1.1e-101 G Glycogen debranching enzyme
IPEPIGIO_02264 5.3e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IPEPIGIO_02265 7.9e-156 yjdB S Domain of unknown function (DUF4767)
IPEPIGIO_02266 2.6e-149 Q Fumarylacetoacetate (FAA) hydrolase family
IPEPIGIO_02267 5.3e-72 asp2 S Asp23 family, cell envelope-related function
IPEPIGIO_02268 8.7e-72 asp S Asp23 family, cell envelope-related function
IPEPIGIO_02269 7.2e-23
IPEPIGIO_02270 4.4e-84
IPEPIGIO_02271 7.1e-37 S Transglycosylase associated protein
IPEPIGIO_02272 0.0 XK27_09800 I Acyltransferase family
IPEPIGIO_02273 1.8e-36 S MORN repeat
IPEPIGIO_02274 4.6e-25 S Cysteine-rich secretory protein family
IPEPIGIO_02275 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02276 2e-77 merR K MerR family regulatory protein
IPEPIGIO_02277 9e-156 1.6.5.2 GM NmrA-like family
IPEPIGIO_02278 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
IPEPIGIO_02279 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
IPEPIGIO_02280 1.4e-08
IPEPIGIO_02281 1.1e-77 S NADPH-dependent FMN reductase
IPEPIGIO_02282 7.9e-238 S module of peptide synthetase
IPEPIGIO_02283 8.4e-105
IPEPIGIO_02284 1.3e-87 perR P Belongs to the Fur family
IPEPIGIO_02285 7.1e-59 S Enterocin A Immunity
IPEPIGIO_02286 5.4e-36 S Phospholipase_D-nuclease N-terminal
IPEPIGIO_02287 2.1e-60 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
IPEPIGIO_02288 2.1e-78 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
IPEPIGIO_02289 3.8e-104 J Acetyltransferase (GNAT) domain
IPEPIGIO_02290 5.1e-64 lrgA S LrgA family
IPEPIGIO_02291 7.3e-127 lrgB M LrgB-like family
IPEPIGIO_02292 7.1e-145 DegV S EDD domain protein, DegV family
IPEPIGIO_02293 4.1e-25
IPEPIGIO_02294 5e-117 yugP S Putative neutral zinc metallopeptidase
IPEPIGIO_02295 2.6e-291 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
IPEPIGIO_02296 5.5e-278 bmr3 EGP Major facilitator Superfamily
IPEPIGIO_02297 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPEPIGIO_02298 1.6e-121
IPEPIGIO_02299 1.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
IPEPIGIO_02300 7.5e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IPEPIGIO_02301 9.2e-256 mmuP E amino acid
IPEPIGIO_02302 4e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IPEPIGIO_02303 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
IPEPIGIO_02305 3.3e-104 T Calcineurin-like phosphoesterase superfamily domain
IPEPIGIO_02306 8.6e-37 T Calcineurin-like phosphoesterase superfamily domain
IPEPIGIO_02307 2e-94 K Acetyltransferase (GNAT) domain
IPEPIGIO_02308 1.4e-95
IPEPIGIO_02309 1.8e-182 P secondary active sulfate transmembrane transporter activity
IPEPIGIO_02310 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
IPEPIGIO_02316 5.1e-08
IPEPIGIO_02322 0.0 traA L MobA/MobL family
IPEPIGIO_02323 2e-177 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPEPIGIO_02324 2e-07 S Domain of unknown function (DUF4411)
IPEPIGIO_02325 2e-27 M Glycosyl transferase 4-like
IPEPIGIO_02326 2.6e-52 M Glycosyltransferase sugar-binding region containing DXD motif
IPEPIGIO_02327 7.3e-21 M PFAM Glycosyl transferase family 2
IPEPIGIO_02328 4.8e-13
IPEPIGIO_02329 1.5e-61 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
IPEPIGIO_02330 1.7e-43 L PFAM Integrase, catalytic core
IPEPIGIO_02332 1.5e-232 cps1C S Polysaccharide biosynthesis protein
IPEPIGIO_02333 6.2e-114 tra L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02334 1.2e-44 M Glycosyltransferase, group 2 family protein
IPEPIGIO_02335 2.4e-44 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02336 2.2e-170 L Integrase core domain
IPEPIGIO_02337 9.5e-46 L Transposase
IPEPIGIO_02338 2.3e-107 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02339 3.5e-123
IPEPIGIO_02340 4.1e-59
IPEPIGIO_02341 1.1e-279 lldP C L-lactate permease
IPEPIGIO_02342 3.9e-227
IPEPIGIO_02343 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IPEPIGIO_02344 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IPEPIGIO_02345 6.8e-217 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPEPIGIO_02346 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPEPIGIO_02347 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IPEPIGIO_02348 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
IPEPIGIO_02349 9.3e-253 gshR1 1.8.1.7 C Glutathione reductase
IPEPIGIO_02350 1.8e-66
IPEPIGIO_02351 6.3e-246 M Glycosyl transferase family group 2
IPEPIGIO_02352 1.2e-39 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPEPIGIO_02353 2.8e-36 EGP Major facilitator Superfamily
IPEPIGIO_02354 4.3e-86 yhbO 3.5.1.124 S Intracellular protease
IPEPIGIO_02355 6.2e-154 L Integrase core domain
IPEPIGIO_02356 9.8e-39 L Transposase and inactivated derivatives
IPEPIGIO_02357 5.6e-95 tnpR1 L Resolvase, N terminal domain
IPEPIGIO_02358 2e-61 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IPEPIGIO_02360 4.7e-81 nrdI F NrdI Flavodoxin like
IPEPIGIO_02361 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPEPIGIO_02362 6.1e-171 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
IPEPIGIO_02363 6.1e-182 1.17.4.1 F Ribonucleotide reductase, small chain
IPEPIGIO_02364 4.2e-115 L hmm pf00665
IPEPIGIO_02365 9.5e-107 L Resolvase, N terminal domain
IPEPIGIO_02366 2.1e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IPEPIGIO_02367 4.9e-78 yneH 1.20.4.1 K ArsC family
IPEPIGIO_02368 7.4e-135 K LytTr DNA-binding domain
IPEPIGIO_02369 8.7e-160 2.7.13.3 T GHKL domain
IPEPIGIO_02370 1.8e-12
IPEPIGIO_02371 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
IPEPIGIO_02372 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
IPEPIGIO_02374 8.3e-52 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IPEPIGIO_02375 1.1e-130 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IPEPIGIO_02376 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IPEPIGIO_02377 8.7e-72 K Transcriptional regulator
IPEPIGIO_02378 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IPEPIGIO_02379 7.3e-33 S Protein of unknown function (DUF2922)
IPEPIGIO_02380 7e-30
IPEPIGIO_02381 1.3e-25
IPEPIGIO_02382 6.8e-101 K DNA-templated transcription, initiation
IPEPIGIO_02383 3e-125
IPEPIGIO_02384 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
IPEPIGIO_02385 4.1e-106 ygaC J Belongs to the UPF0374 family
IPEPIGIO_02386 2.5e-133 cwlO M NlpC/P60 family
IPEPIGIO_02387 7.8e-48 K sequence-specific DNA binding
IPEPIGIO_02388 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
IPEPIGIO_02389 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IPEPIGIO_02390 9.3e-188 yueF S AI-2E family transporter
IPEPIGIO_02391 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IPEPIGIO_02392 9.5e-213 gntP EG Gluconate
IPEPIGIO_02393 3e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
IPEPIGIO_02394 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
IPEPIGIO_02395 3.2e-308 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
IPEPIGIO_02396 6e-76
IPEPIGIO_02397 1.6e-140 S Belongs to the UPF0246 family
IPEPIGIO_02398 3e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IPEPIGIO_02399 2.3e-235 mepA V MATE efflux family protein
IPEPIGIO_02400 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
IPEPIGIO_02401 5.4e-181 1.1.1.1 C nadph quinone reductase
IPEPIGIO_02402 2e-126 hchA S DJ-1/PfpI family
IPEPIGIO_02403 3.6e-93 MA20_25245 K FR47-like protein
IPEPIGIO_02404 3.6e-152 EG EamA-like transporter family
IPEPIGIO_02405 2.1e-61 S Protein of unknown function
IPEPIGIO_02406 8.2e-39 S Protein of unknown function
IPEPIGIO_02407 0.0 tetP J elongation factor G
IPEPIGIO_02408 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPEPIGIO_02409 5.5e-172 yobV1 K WYL domain
IPEPIGIO_02410 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
IPEPIGIO_02411 2.9e-81 6.3.3.2 S ASCH
IPEPIGIO_02412 6.9e-254 1.14.14.9 Q 4-hydroxyphenylacetate
IPEPIGIO_02413 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
IPEPIGIO_02414 7.4e-250 yjjP S Putative threonine/serine exporter
IPEPIGIO_02415 3.3e-194 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IPEPIGIO_02416 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IPEPIGIO_02417 1.3e-290 QT PucR C-terminal helix-turn-helix domain
IPEPIGIO_02418 1.3e-122 drgA C Nitroreductase family
IPEPIGIO_02419 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IPEPIGIO_02420 2.3e-164 ptlF S KR domain
IPEPIGIO_02421 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPEPIGIO_02422 1e-72 C FMN binding
IPEPIGIO_02423 5.7e-158 K LysR family
IPEPIGIO_02424 1.6e-258 P Sodium:sulfate symporter transmembrane region
IPEPIGIO_02425 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
IPEPIGIO_02426 1.8e-116 S Elongation factor G-binding protein, N-terminal
IPEPIGIO_02427 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
IPEPIGIO_02428 2.8e-66 pnb C nitroreductase
IPEPIGIO_02429 4.2e-32 pnb C nitroreductase
IPEPIGIO_02430 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
IPEPIGIO_02431 1.5e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IPEPIGIO_02432 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
IPEPIGIO_02433 1.5e-95 K Bacterial regulatory proteins, tetR family
IPEPIGIO_02434 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IPEPIGIO_02435 6.8e-173 htrA 3.4.21.107 O serine protease
IPEPIGIO_02436 8.9e-158 vicX 3.1.26.11 S domain protein
IPEPIGIO_02437 2.2e-151 yycI S YycH protein
IPEPIGIO_02438 1.2e-244 yycH S YycH protein
IPEPIGIO_02439 0.0 vicK 2.7.13.3 T Histidine kinase
IPEPIGIO_02440 6.2e-131 K response regulator
IPEPIGIO_02442 1.7e-37
IPEPIGIO_02443 1.6e-31 cspA K Cold shock protein domain
IPEPIGIO_02444 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
IPEPIGIO_02445 4.5e-97 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
IPEPIGIO_02446 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
IPEPIGIO_02447 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IPEPIGIO_02448 4.5e-143 S haloacid dehalogenase-like hydrolase
IPEPIGIO_02450 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
IPEPIGIO_02451 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IPEPIGIO_02452 2e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
IPEPIGIO_02453 7e-196 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
IPEPIGIO_02454 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IPEPIGIO_02455 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IPEPIGIO_02456 4.2e-276 E ABC transporter, substratebinding protein
IPEPIGIO_02458 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPEPIGIO_02459 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPEPIGIO_02460 8.8e-226 yttB EGP Major facilitator Superfamily
IPEPIGIO_02461 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IPEPIGIO_02462 1.4e-67 rplI J Binds to the 23S rRNA
IPEPIGIO_02463 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IPEPIGIO_02464 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPEPIGIO_02465 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IPEPIGIO_02466 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IPEPIGIO_02467 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPEPIGIO_02468 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPEPIGIO_02469 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPEPIGIO_02470 5e-37 yaaA S S4 domain protein YaaA
IPEPIGIO_02471 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IPEPIGIO_02472 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPEPIGIO_02473 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IPEPIGIO_02474 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IPEPIGIO_02475 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPEPIGIO_02476 1e-309 E ABC transporter, substratebinding protein
IPEPIGIO_02477 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
IPEPIGIO_02478 9.1e-109 jag S R3H domain protein
IPEPIGIO_02479 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPEPIGIO_02480 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IPEPIGIO_02481 5.9e-92 S Cell surface protein
IPEPIGIO_02482 3e-158 S Bacterial protein of unknown function (DUF916)
IPEPIGIO_02484 1.1e-302
IPEPIGIO_02485 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IPEPIGIO_02487 1.5e-255 pepC 3.4.22.40 E aminopeptidase
IPEPIGIO_02488 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
IPEPIGIO_02489 8.9e-156 degV S DegV family
IPEPIGIO_02490 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
IPEPIGIO_02491 6.7e-142 tesE Q hydratase
IPEPIGIO_02492 1.1e-64 padC Q Phenolic acid decarboxylase
IPEPIGIO_02493 7.3e-109 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02494 2.3e-118 D Alpha beta
IPEPIGIO_02495 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IPEPIGIO_02496 1.9e-258 gor 1.8.1.7 C Glutathione reductase
IPEPIGIO_02497 9.8e-55 S Enterocin A Immunity
IPEPIGIO_02498 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPEPIGIO_02499 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPEPIGIO_02500 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPEPIGIO_02501 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
IPEPIGIO_02502 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPEPIGIO_02504 2.1e-82
IPEPIGIO_02505 2.1e-105 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPEPIGIO_02506 6.2e-117 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPEPIGIO_02508 2.7e-29 M Lysin motif
IPEPIGIO_02509 2.5e-76 L HTH-like domain
IPEPIGIO_02510 8.4e-224 oxlT P Major Facilitator Superfamily
IPEPIGIO_02511 9.5e-92 L Helix-turn-helix domain
IPEPIGIO_02512 2.5e-76 L HTH-like domain
IPEPIGIO_02513 0.0 uvrA2 L ABC transporter
IPEPIGIO_02514 3e-102 L Resolvase, N terminal domain
IPEPIGIO_02515 1.5e-77 sufB O assembly protein SufB
IPEPIGIO_02516 7.7e-101 yvbG U MarC family integral membrane protein
IPEPIGIO_02517 1.7e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02519 1.7e-08
IPEPIGIO_02520 2.4e-53
IPEPIGIO_02521 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IPEPIGIO_02522 2.7e-79 T Universal stress protein family
IPEPIGIO_02523 2.2e-99 padR K Virulence activator alpha C-term
IPEPIGIO_02524 9.2e-28 padC Q Phenolic acid decarboxylase
IPEPIGIO_02525 1.5e-109 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02526 1.9e-57
IPEPIGIO_02527 6e-31 cspA K Cold shock protein
IPEPIGIO_02528 3.8e-40
IPEPIGIO_02529 4.9e-16
IPEPIGIO_02530 2.3e-107 L Integrase
IPEPIGIO_02531 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
IPEPIGIO_02532 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IPEPIGIO_02533 1.2e-51 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IPEPIGIO_02534 3.1e-56 tnp2PF3 L Transposase DDE domain
IPEPIGIO_02535 9.1e-153 cjaA ET ABC transporter substrate-binding protein
IPEPIGIO_02536 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPEPIGIO_02537 4.3e-113 P ABC transporter permease
IPEPIGIO_02538 4.2e-113 papP P ABC transporter, permease protein
IPEPIGIO_02539 4.1e-137 S Protease prsW family
IPEPIGIO_02540 2.5e-31
IPEPIGIO_02541 2.7e-23
IPEPIGIO_02542 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPEPIGIO_02543 4.9e-172 K AI-2E family transporter
IPEPIGIO_02544 1.7e-210 xylR GK ROK family
IPEPIGIO_02545 2.3e-81
IPEPIGIO_02546 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IPEPIGIO_02547 3.9e-162
IPEPIGIO_02548 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IPEPIGIO_02549 6e-140 K Helix-turn-helix domain
IPEPIGIO_02550 2.9e-38 S TfoX C-terminal domain
IPEPIGIO_02551 1e-227 hpk9 2.7.13.3 T GHKL domain
IPEPIGIO_02552 8.4e-263
IPEPIGIO_02553 8.4e-75
IPEPIGIO_02554 3.6e-183 S Cell surface protein
IPEPIGIO_02555 1.7e-101 S WxL domain surface cell wall-binding
IPEPIGIO_02557 2.7e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
IPEPIGIO_02559 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IPEPIGIO_02560 1.3e-81 gpG
IPEPIGIO_02561 6.8e-57 S Domain of unknown function (DUF4355)
IPEPIGIO_02562 8.9e-11 S Domain of unknown function (DUF4355)
IPEPIGIO_02563 5.9e-12
IPEPIGIO_02564 3.7e-241 iolT EGP Major facilitator Superfamily
IPEPIGIO_02565 2e-162 yxaB GM Polysaccharide pyruvyl transferase
IPEPIGIO_02566 1.8e-80 EGP Major facilitator Superfamily
IPEPIGIO_02567 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02568 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
IPEPIGIO_02569 6.7e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPEPIGIO_02570 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IPEPIGIO_02571 2.7e-160 rbsU U ribose uptake protein RbsU
IPEPIGIO_02572 3.8e-145 IQ NAD dependent epimerase/dehydratase family
IPEPIGIO_02573 1.3e-279 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
IPEPIGIO_02574 7.6e-52 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
IPEPIGIO_02575 1.1e-86 gutM K Glucitol operon activator protein (GutM)
IPEPIGIO_02576 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
IPEPIGIO_02577 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
IPEPIGIO_02578 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IPEPIGIO_02579 3.6e-24 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IPEPIGIO_02580 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02581 1.7e-158 glpQ 3.1.4.46 C phosphodiesterase
IPEPIGIO_02582 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IPEPIGIO_02583 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
IPEPIGIO_02584 8.9e-284 M domain protein
IPEPIGIO_02585 0.0 ydgH S MMPL family
IPEPIGIO_02586 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02587 6.2e-44 S Psort location CytoplasmicMembrane, score
IPEPIGIO_02588 8.3e-176 L Initiator Replication protein
IPEPIGIO_02589 5.8e-32
IPEPIGIO_02590 5.9e-26 K Transcriptional
IPEPIGIO_02591 1.2e-68
IPEPIGIO_02592 3.4e-106 L Phage integrase family
IPEPIGIO_02593 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IPEPIGIO_02594 7.1e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
IPEPIGIO_02596 8.9e-28
IPEPIGIO_02597 3.4e-27 S Protein of unknown function (DUF1093)
IPEPIGIO_02598 7.3e-21 3.4.21.19 M Belongs to the peptidase S1B family
IPEPIGIO_02599 2.8e-22 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPEPIGIO_02600 3.4e-72 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_02601 1.6e-14 K Bacterial regulatory proteins, tetR family
IPEPIGIO_02602 4.7e-214 S membrane
IPEPIGIO_02603 4.1e-82 K Bacterial regulatory proteins, tetR family
IPEPIGIO_02604 0.0 CP_1020 S Zinc finger, swim domain protein
IPEPIGIO_02605 2e-112 GM epimerase
IPEPIGIO_02606 4.1e-68 S Protein of unknown function (DUF1722)
IPEPIGIO_02607 9.1e-71 yneH 1.20.4.1 P ArsC family
IPEPIGIO_02608 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
IPEPIGIO_02609 8e-137 K DeoR C terminal sensor domain
IPEPIGIO_02610 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPEPIGIO_02611 9.2e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IPEPIGIO_02612 4.3e-77 K Transcriptional regulator
IPEPIGIO_02613 2.2e-241 EGP Major facilitator Superfamily
IPEPIGIO_02614 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IPEPIGIO_02615 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
IPEPIGIO_02616 2.6e-180 C Zinc-binding dehydrogenase
IPEPIGIO_02617 7.4e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
IPEPIGIO_02618 1.7e-207
IPEPIGIO_02619 4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
IPEPIGIO_02620 7.8e-61 P Rhodanese Homology Domain
IPEPIGIO_02621 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IPEPIGIO_02622 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
IPEPIGIO_02623 3.2e-167 drrA V ABC transporter
IPEPIGIO_02624 2e-119 drrB U ABC-2 type transporter
IPEPIGIO_02625 6.9e-223 M O-Antigen ligase
IPEPIGIO_02626 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
IPEPIGIO_02627 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IPEPIGIO_02628 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IPEPIGIO_02629 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IPEPIGIO_02631 5.6e-29 S Protein of unknown function (DUF2929)
IPEPIGIO_02632 0.0 dnaE 2.7.7.7 L DNA polymerase
IPEPIGIO_02633 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IPEPIGIO_02634 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IPEPIGIO_02635 1.5e-74 yeaL S Protein of unknown function (DUF441)
IPEPIGIO_02636 1.1e-169 cvfB S S1 domain
IPEPIGIO_02637 1.1e-164 xerD D recombinase XerD
IPEPIGIO_02638 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPEPIGIO_02639 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPEPIGIO_02640 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPEPIGIO_02641 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IPEPIGIO_02642 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IPEPIGIO_02643 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
IPEPIGIO_02644 6.2e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IPEPIGIO_02645 2e-19 M Lysin motif
IPEPIGIO_02646 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IPEPIGIO_02647 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
IPEPIGIO_02648 1e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IPEPIGIO_02649 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IPEPIGIO_02650 2.1e-206 S Tetratricopeptide repeat protein
IPEPIGIO_02651 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
IPEPIGIO_02652 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IPEPIGIO_02653 2.1e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IPEPIGIO_02654 9.6e-85
IPEPIGIO_02655 0.0 yfmR S ABC transporter, ATP-binding protein
IPEPIGIO_02656 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPEPIGIO_02657 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPEPIGIO_02658 5.1e-148 DegV S EDD domain protein, DegV family
IPEPIGIO_02659 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
IPEPIGIO_02660 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IPEPIGIO_02661 3.4e-35 yozE S Belongs to the UPF0346 family
IPEPIGIO_02662 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IPEPIGIO_02663 7.3e-251 emrY EGP Major facilitator Superfamily
IPEPIGIO_02664 5.7e-197 XK27_00915 C Luciferase-like monooxygenase
IPEPIGIO_02665 4.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IPEPIGIO_02666 2.3e-173 L restriction endonuclease
IPEPIGIO_02667 3.1e-170 cpsY K Transcriptional regulator, LysR family
IPEPIGIO_02668 6.8e-228 XK27_05470 E Methionine synthase
IPEPIGIO_02670 4.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IPEPIGIO_02671 8.2e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPEPIGIO_02672 3.3e-158 dprA LU DNA protecting protein DprA
IPEPIGIO_02673 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPEPIGIO_02674 6.6e-251 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IPEPIGIO_02675 2.6e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
IPEPIGIO_02676 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IPEPIGIO_02677 8.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IPEPIGIO_02678 3.8e-170 lacX 5.1.3.3 G Aldose 1-epimerase
IPEPIGIO_02679 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IPEPIGIO_02680 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPEPIGIO_02681 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPEPIGIO_02682 2.3e-176 K Transcriptional regulator
IPEPIGIO_02683 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
IPEPIGIO_02684 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IPEPIGIO_02685 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPEPIGIO_02686 1.2e-09 S YozE SAM-like fold
IPEPIGIO_02687 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02688 1.3e-87 K Winged helix DNA-binding domain
IPEPIGIO_02689 5.3e-116 luxT K Bacterial regulatory proteins, tetR family
IPEPIGIO_02690 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IPEPIGIO_02691 1.8e-27
IPEPIGIO_02692 7.2e-280 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
IPEPIGIO_02693 2e-72 mltD CBM50 M PFAM NLP P60 protein
IPEPIGIO_02694 2.5e-53
IPEPIGIO_02695 1.6e-61
IPEPIGIO_02697 1.5e-109 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02698 9.2e-213 glnA 6.3.1.2 E glutamine synthetase
IPEPIGIO_02699 6e-52 ykoF S YKOF-related Family
IPEPIGIO_02700 6.4e-46 M domain protein
IPEPIGIO_02701 5.4e-64 tcmJ G COG0662 Mannose-6-phosphate isomerase
IPEPIGIO_02702 1.1e-95 tnp L DDE domain
IPEPIGIO_02703 4e-151 glcU U sugar transport
IPEPIGIO_02704 4.8e-244 dinF V MatE
IPEPIGIO_02705 1.9e-31
IPEPIGIO_02708 1.5e-77 elaA S Acetyltransferase (GNAT) domain
IPEPIGIO_02709 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IPEPIGIO_02710 1.4e-81
IPEPIGIO_02711 0.0 yhcA V MacB-like periplasmic core domain
IPEPIGIO_02712 1.4e-38
IPEPIGIO_02713 7.4e-24
IPEPIGIO_02714 4.2e-167 traA L MobA MobL family protein
IPEPIGIO_02715 2e-200 traA L MobA MobL family protein
IPEPIGIO_02716 2e-255 ykgC 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IPEPIGIO_02717 1.5e-115 L Transposase IS66 family
IPEPIGIO_02718 4.9e-160 L Transposase IS66 family
IPEPIGIO_02719 4.5e-58 XK27_01125 L PFAM IS66 Orf2 family protein
IPEPIGIO_02720 2.6e-25
IPEPIGIO_02721 5.7e-146 tatD L hydrolase, TatD family
IPEPIGIO_02722 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IPEPIGIO_02723 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IPEPIGIO_02724 3.2e-37 veg S Biofilm formation stimulator VEG
IPEPIGIO_02725 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPEPIGIO_02726 1.3e-181 S Prolyl oligopeptidase family
IPEPIGIO_02727 9.8e-129 fhuC 3.6.3.35 P ABC transporter
IPEPIGIO_02728 9.2e-131 znuB U ABC 3 transport family
IPEPIGIO_02729 4.3e-46 L Transposase
IPEPIGIO_02731 2.3e-34
IPEPIGIO_02732 4.2e-144 soj D AAA domain
IPEPIGIO_02734 1.1e-129 repA S Replication initiator protein A
IPEPIGIO_02735 4.7e-20 lacA 3.2.1.23 G -beta-galactosidase
IPEPIGIO_02736 1.9e-64 lacA 3.2.1.23 G -beta-galactosidase
IPEPIGIO_02737 3.4e-219 lacA 3.2.1.23 G -beta-galactosidase
IPEPIGIO_02738 0.0 lacS G Transporter
IPEPIGIO_02739 2.6e-71 brnQ U Component of the transport system for branched-chain amino acids
IPEPIGIO_02740 0.0 M Glycosyl hydrolases family 25
IPEPIGIO_02741 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IPEPIGIO_02742 2e-166 GM NmrA-like family
IPEPIGIO_02743 2e-69 S Protein of unknown function with HXXEE motif
IPEPIGIO_02744 4e-178 xopQ 3.2.2.1, 3.2.2.8 F inosine-uridine preferring nucleoside hydrolase
IPEPIGIO_02745 1.6e-101 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPEPIGIO_02746 0.0 L MobA MobL family protein
IPEPIGIO_02747 6.3e-137 ywqE 3.1.3.48 GM PHP domain protein
IPEPIGIO_02748 1.1e-127 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IPEPIGIO_02749 3.1e-120 epsB M biosynthesis protein
IPEPIGIO_02750 1.4e-47 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02751 3.3e-95 tnpR1 L Resolvase, N terminal domain
IPEPIGIO_02752 2.9e-38 L Transposase and inactivated derivatives
IPEPIGIO_02753 7.8e-140 L COG2801 Transposase and inactivated derivatives
IPEPIGIO_02754 4.7e-117 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
IPEPIGIO_02755 5.1e-129 S WxL domain surface cell wall-binding
IPEPIGIO_02756 5.8e-186 S Bacterial protein of unknown function (DUF916)
IPEPIGIO_02757 0.0
IPEPIGIO_02758 6e-161 ypuA S Protein of unknown function (DUF1002)
IPEPIGIO_02759 5.5e-50 yvlA
IPEPIGIO_02760 1.2e-95 K transcriptional regulator
IPEPIGIO_02761 2.7e-91 ymdB S Macro domain protein
IPEPIGIO_02762 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IPEPIGIO_02763 2.3e-43 S Protein of unknown function (DUF1093)
IPEPIGIO_02764 7.5e-77 S Threonine/Serine exporter, ThrE
IPEPIGIO_02765 9.2e-133 thrE S Putative threonine/serine exporter
IPEPIGIO_02766 5.2e-164 yvgN C Aldo keto reductase
IPEPIGIO_02767 8.4e-152 ywkB S Membrane transport protein
IPEPIGIO_02768 6.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IPEPIGIO_02769 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
IPEPIGIO_02770 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
IPEPIGIO_02771 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
IPEPIGIO_02772 6.8e-181 D Alpha beta
IPEPIGIO_02773 8.9e-210 mdtG EGP Major facilitator Superfamily
IPEPIGIO_02774 1.4e-220 sip L Belongs to the 'phage' integrase family
IPEPIGIO_02775 1.6e-08 K transcriptional
IPEPIGIO_02777 1.1e-81 S Phage regulatory protein Rha (Phage_pRha)
IPEPIGIO_02778 3.2e-41
IPEPIGIO_02780 9.2e-45
IPEPIGIO_02781 3.6e-29
IPEPIGIO_02782 7.8e-135 L Primase C terminal 1 (PriCT-1)
IPEPIGIO_02783 7e-235 S Virulence-associated protein E
IPEPIGIO_02785 7.2e-62
IPEPIGIO_02786 3.5e-29
IPEPIGIO_02787 5.7e-55
IPEPIGIO_02789 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
IPEPIGIO_02790 1.6e-64 ycgX S Protein of unknown function (DUF1398)
IPEPIGIO_02791 4.2e-49
IPEPIGIO_02792 3.4e-25
IPEPIGIO_02793 1.5e-248 lmrB EGP Major facilitator Superfamily
IPEPIGIO_02794 7.7e-73 S COG NOG18757 non supervised orthologous group
IPEPIGIO_02795 7.4e-40
IPEPIGIO_02796 4.7e-73 copR K Copper transport repressor CopY TcrY
IPEPIGIO_02797 0.0 copB 3.6.3.4 P P-type ATPase
IPEPIGIO_02798 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IPEPIGIO_02799 6.8e-111 S VIT family
IPEPIGIO_02800 1.8e-119 S membrane
IPEPIGIO_02801 5.9e-158 EG EamA-like transporter family
IPEPIGIO_02802 1.3e-81 elaA S GNAT family
IPEPIGIO_02803 1.1e-115 GM NmrA-like family
IPEPIGIO_02804 2.1e-14
IPEPIGIO_02805 5.9e-55
IPEPIGIO_02806 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
IPEPIGIO_02807 4.3e-86
IPEPIGIO_02808 1.9e-62
IPEPIGIO_02809 4.1e-214 mutY L A G-specific adenine glycosylase
IPEPIGIO_02810 4e-53
IPEPIGIO_02811 1.7e-66 yeaO S Protein of unknown function, DUF488
IPEPIGIO_02812 7e-71 spx4 1.20.4.1 P ArsC family
IPEPIGIO_02813 5.4e-66 K Winged helix DNA-binding domain
IPEPIGIO_02814 7.7e-160 azoB GM NmrA-like family
IPEPIGIO_02815 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IPEPIGIO_02816 2.7e-71 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_02817 5.7e-73 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_02818 4.4e-250 cycA E Amino acid permease
IPEPIGIO_02819 3.4e-253 nhaC C Na H antiporter NhaC
IPEPIGIO_02820 3e-26 3.2.2.10 S Belongs to the LOG family
IPEPIGIO_02821 2.2e-199 frlB M SIS domain
IPEPIGIO_02822 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IPEPIGIO_02823 2.8e-168 S Uncharacterized protein conserved in bacteria (DUF2325)
IPEPIGIO_02824 2.9e-29 S Uncharacterized protein conserved in bacteria (DUF2325)
IPEPIGIO_02825 1.8e-124 yyaQ S YjbR
IPEPIGIO_02827 0.0 cadA P P-type ATPase
IPEPIGIO_02828 2e-305 U Belongs to the BCCT transporter (TC 2.A.15) family
IPEPIGIO_02829 2.4e-121 E GDSL-like Lipase/Acylhydrolase family
IPEPIGIO_02830 1.4e-77
IPEPIGIO_02831 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
IPEPIGIO_02832 3.3e-97 FG HIT domain
IPEPIGIO_02833 1.7e-173 S Aldo keto reductase
IPEPIGIO_02834 1.9e-52 yitW S Pfam:DUF59
IPEPIGIO_02835 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IPEPIGIO_02836 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
IPEPIGIO_02837 5e-195 blaA6 V Beta-lactamase
IPEPIGIO_02838 6.2e-96 V VanZ like family
IPEPIGIO_02839 7.9e-108 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02840 4.4e-80 L PFAM Integrase catalytic region
IPEPIGIO_02841 1.7e-88 L Helix-turn-helix domain
IPEPIGIO_02842 6.5e-290 clcA P chloride
IPEPIGIO_02843 1.1e-193 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPEPIGIO_02844 4.6e-53
IPEPIGIO_02845 5.1e-238 EGP Major Facilitator Superfamily
IPEPIGIO_02846 0.0 mco Q Multicopper oxidase
IPEPIGIO_02847 4.7e-25
IPEPIGIO_02849 2.6e-123 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02850 3.4e-25 L transposase and inactivated derivatives, IS30 family
IPEPIGIO_02851 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
IPEPIGIO_02852 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IPEPIGIO_02853 4.4e-130 S haloacid dehalogenase-like hydrolase
IPEPIGIO_02854 2.2e-177 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPEPIGIO_02855 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
IPEPIGIO_02856 3e-13 S YozE SAM-like fold
IPEPIGIO_02858 1.7e-38 sirR K Helix-turn-helix diphteria tox regulatory element
IPEPIGIO_02859 6.7e-250 mntH P H( )-stimulated, divalent metal cation uptake system
IPEPIGIO_02860 1e-56 T Belongs to the universal stress protein A family
IPEPIGIO_02861 1e-96 tnpR1 L Resolvase, N terminal domain
IPEPIGIO_02862 6.3e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
IPEPIGIO_02863 3.2e-34
IPEPIGIO_02864 3.5e-157 repA S Replication initiator protein A
IPEPIGIO_02865 1e-27
IPEPIGIO_02866 1e-136 S Fic/DOC family
IPEPIGIO_02867 2.6e-61 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_02868 1.1e-15
IPEPIGIO_02869 1.3e-11 S Transglycosylase associated protein
IPEPIGIO_02870 1.6e-73 S cog cog1302
IPEPIGIO_02871 1.9e-23 S Small integral membrane protein (DUF2273)
IPEPIGIO_02872 1.3e-91
IPEPIGIO_02873 4.8e-148 3.4.13.21 E Belongs to the peptidase S51 family
IPEPIGIO_02874 8.8e-95 L 4.5 Transposon and IS
IPEPIGIO_02875 1.1e-56 hxlR K HxlR-like helix-turn-helix
IPEPIGIO_02876 7.6e-110 XK27_07075 V CAAX protease self-immunity
IPEPIGIO_02877 1.7e-63 K Helix-turn-helix XRE-family like proteins
IPEPIGIO_02878 6.2e-50
IPEPIGIO_02879 4.4e-19
IPEPIGIO_02880 4.5e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
IPEPIGIO_02881 3.6e-11
IPEPIGIO_02882 9e-13 ytgB S Transglycosylase associated protein
IPEPIGIO_02883 5.4e-291 katA 1.11.1.6 C Belongs to the catalase family
IPEPIGIO_02884 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IPEPIGIO_02885 1.4e-154 yihY S Belongs to the UPF0761 family
IPEPIGIO_02886 1.5e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IPEPIGIO_02887 1.2e-219 pbpX1 V Beta-lactamase
IPEPIGIO_02888 1.9e-253 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IPEPIGIO_02889 5e-107
IPEPIGIO_02890 1.3e-73
IPEPIGIO_02892 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_02893 1.4e-242 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPEPIGIO_02894 2.3e-75 T Universal stress protein family
IPEPIGIO_02895 9.6e-30 hol S Bacteriophage holin
IPEPIGIO_02896 1.1e-35 S Haemolysin XhlA
IPEPIGIO_02897 1.8e-193 lys M Glycosyl hydrolases family 25
IPEPIGIO_02898 1.2e-16
IPEPIGIO_02899 4.4e-82
IPEPIGIO_02902 1.4e-189
IPEPIGIO_02903 0.0 S Phage minor structural protein
IPEPIGIO_02904 0.0 S Phage tail protein
IPEPIGIO_02905 0.0 D NLP P60 protein
IPEPIGIO_02906 6.6e-24
IPEPIGIO_02907 2.8e-58 S Phage tail assembly chaperone proteins, TAC
IPEPIGIO_02908 3e-103 S Phage tail tube protein
IPEPIGIO_02909 3.5e-56 S Protein of unknown function (DUF806)
IPEPIGIO_02910 5.2e-66 S Bacteriophage HK97-gp10, putative tail-component
IPEPIGIO_02911 6.5e-57 S Phage head-tail joining protein
IPEPIGIO_02912 8.1e-49 S Phage gp6-like head-tail connector protein
IPEPIGIO_02913 3e-202 S Phage capsid family
IPEPIGIO_02914 1.1e-125 S Clp protease
IPEPIGIO_02915 8.9e-223 S Phage portal protein
IPEPIGIO_02916 1.1e-26 S Protein of unknown function (DUF1056)
IPEPIGIO_02917 0.0 S Phage Terminase
IPEPIGIO_02918 1.8e-78 L Phage terminase, small subunit
IPEPIGIO_02920 8e-88 L HNH nucleases
IPEPIGIO_02922 5.5e-43
IPEPIGIO_02923 7.7e-76 S Transcriptional regulator, RinA family
IPEPIGIO_02924 2.5e-185
IPEPIGIO_02925 6.8e-32 S YopX protein
IPEPIGIO_02927 5e-15
IPEPIGIO_02928 4.9e-66 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IPEPIGIO_02929 2.4e-84
IPEPIGIO_02931 9.9e-146 pi346 L IstB-like ATP binding protein
IPEPIGIO_02932 4.5e-55 L DnaD domain protein
IPEPIGIO_02934 3.9e-130 S Putative HNHc nuclease
IPEPIGIO_02935 2.8e-43 S Single-strand binding protein family
IPEPIGIO_02936 2.3e-63 S ERF superfamily
IPEPIGIO_02940 2.6e-16
IPEPIGIO_02945 1.4e-91 kilA K BRO family, N-terminal domain
IPEPIGIO_02947 5.8e-18 ps115 K Cro/C1-type HTH DNA-binding domain
IPEPIGIO_02951 1e-09 S PFAM Pyruvate kinase, alpha beta domain
IPEPIGIO_02953 1.3e-80 int L Belongs to the 'phage' integrase family
IPEPIGIO_02955 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
IPEPIGIO_02956 2.4e-189 mocA S Oxidoreductase
IPEPIGIO_02957 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
IPEPIGIO_02958 1.1e-62 S Domain of unknown function (DUF4828)
IPEPIGIO_02959 2e-143 lys M Glycosyl hydrolases family 25
IPEPIGIO_02960 2.3e-151 gntR K rpiR family
IPEPIGIO_02961 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
IPEPIGIO_02962 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPEPIGIO_02963 0.0 yfgQ P E1-E2 ATPase
IPEPIGIO_02964 6e-100 yobS K Bacterial regulatory proteins, tetR family
IPEPIGIO_02965 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPEPIGIO_02966 1e-190 yegS 2.7.1.107 G Lipid kinase
IPEPIGIO_02967 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPEPIGIO_02968 2.1e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IPEPIGIO_02969 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPEPIGIO_02970 2.6e-198 camS S sex pheromone
IPEPIGIO_02971 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPEPIGIO_02972 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IPEPIGIO_02973 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IPEPIGIO_02974 1e-93 S UPF0316 protein
IPEPIGIO_02975 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IPEPIGIO_02976 9e-113 acmA 3.2.1.17 NU mannosyl-glycoprotein
IPEPIGIO_02977 3.6e-16 S Oxidoreductase family, NAD-binding Rossmann fold
IPEPIGIO_02978 0.0 traA L MobA/MobL family
IPEPIGIO_02979 1.2e-23 S Family of unknown function (DUF5388)
IPEPIGIO_02980 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IPEPIGIO_02981 8.3e-37 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPEPIGIO_02983 8.1e-169 wbbI M transferase activity, transferring glycosyl groups
IPEPIGIO_02986 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IPEPIGIO_02989 2.1e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IPEPIGIO_02990 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IPEPIGIO_02991 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
IPEPIGIO_02992 1.1e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
IPEPIGIO_02993 3.3e-217 yceI EGP Major facilitator Superfamily
IPEPIGIO_02994 8.1e-98 S Fic/DOC family
IPEPIGIO_02996 3.7e-134 plnD K LytTr DNA-binding domain
IPEPIGIO_02997 2e-93 2.7.13.3 T GHKL domain
IPEPIGIO_02999 2.3e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
IPEPIGIO_03000 4.8e-40
IPEPIGIO_03001 7.8e-129 cbiO P ABC transporter
IPEPIGIO_03002 2.6e-149 P Cobalt transport protein
IPEPIGIO_03003 4.8e-182 nikMN P PDGLE domain
IPEPIGIO_03004 2.1e-120 K Crp-like helix-turn-helix domain
IPEPIGIO_03005 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
IPEPIGIO_03006 3.5e-121 larB S AIR carboxylase
IPEPIGIO_03007 1.8e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IPEPIGIO_03008 2.5e-74 larC 4.99.1.12 S Protein of unknown function DUF111
IPEPIGIO_03009 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IPEPIGIO_03010 1.4e-150 larE S NAD synthase
IPEPIGIO_03011 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
IPEPIGIO_03013 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IPEPIGIO_03014 1.3e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IPEPIGIO_03015 1.3e-111 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IPEPIGIO_03016 9.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
IPEPIGIO_03017 4.3e-135 S peptidase C26
IPEPIGIO_03018 9.8e-302 L HIRAN domain
IPEPIGIO_03019 3.4e-85 F NUDIX domain
IPEPIGIO_03020 2.6e-250 yifK E Amino acid permease
IPEPIGIO_03021 5.2e-122
IPEPIGIO_03022 3.3e-149 ydjP I Alpha/beta hydrolase family
IPEPIGIO_03023 0.0 pacL1 P P-type ATPase
IPEPIGIO_03024 2.9e-142 2.4.2.3 F Phosphorylase superfamily
IPEPIGIO_03025 1.6e-28 KT PspC domain
IPEPIGIO_03026 3.6e-111 S NADPH-dependent FMN reductase
IPEPIGIO_03027 1.2e-74 papX3 K Transcriptional regulator
IPEPIGIO_03028 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
IPEPIGIO_03029 5.8e-82 S Protein of unknown function (DUF3021)
IPEPIGIO_03030 4.7e-227 mdtG EGP Major facilitator Superfamily
IPEPIGIO_03031 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
IPEPIGIO_03032 2.3e-215 yeaN P Transporter, major facilitator family protein
IPEPIGIO_03034 3.4e-160 S reductase
IPEPIGIO_03035 1.2e-165 1.1.1.65 C Aldo keto reductase
IPEPIGIO_03036 4.5e-82 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
IPEPIGIO_03037 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
IPEPIGIO_03038 7.8e-49
IPEPIGIO_03039 2.2e-258
IPEPIGIO_03040 4e-209 C Oxidoreductase
IPEPIGIO_03041 1.9e-150 cbiQ P cobalt transport
IPEPIGIO_03042 0.0 ykoD P ABC transporter, ATP-binding protein
IPEPIGIO_03043 2.5e-98 S UPF0397 protein
IPEPIGIO_03045 1.6e-129 K UbiC transcription regulator-associated domain protein
IPEPIGIO_03046 8.3e-54 K Transcriptional regulator PadR-like family
IPEPIGIO_03047 3e-134
IPEPIGIO_03048 7.6e-149
IPEPIGIO_03049 9.1e-89
IPEPIGIO_03050 1.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IPEPIGIO_03051 2e-169 yjjC V ABC transporter
IPEPIGIO_03052 4.3e-297 M Exporter of polyketide antibiotics
IPEPIGIO_03053 1.1e-116 K Transcriptional regulator
IPEPIGIO_03054 1.8e-276 C Electron transfer flavoprotein FAD-binding domain
IPEPIGIO_03055 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
IPEPIGIO_03057 1.9e-92 K Bacterial regulatory proteins, tetR family
IPEPIGIO_03058 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IPEPIGIO_03059 8e-185 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IPEPIGIO_03060 5.5e-101 dhaL 2.7.1.121 S Dak2
IPEPIGIO_03061 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
IPEPIGIO_03062 7.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IPEPIGIO_03063 1e-190 malR K Transcriptional regulator, LacI family
IPEPIGIO_03064 2e-180 yvdE K helix_turn _helix lactose operon repressor
IPEPIGIO_03065 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IPEPIGIO_03066 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
IPEPIGIO_03067 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
IPEPIGIO_03068 1.4e-161 malD P ABC transporter permease
IPEPIGIO_03069 1.6e-149 malA S maltodextrose utilization protein MalA
IPEPIGIO_03070 5.5e-258 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
IPEPIGIO_03071 4e-209 msmK P Belongs to the ABC transporter superfamily
IPEPIGIO_03072 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IPEPIGIO_03073 0.0 3.2.1.96 G Glycosyl hydrolase family 85
IPEPIGIO_03074 1.5e-109 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_03075 2e-132 S Cysteine-rich secretory protein family
IPEPIGIO_03076 6.7e-232 EGP Major facilitator Superfamily
IPEPIGIO_03077 6.3e-90 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_03078 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
IPEPIGIO_03079 3.7e-31 tnp2PF3 L manually curated
IPEPIGIO_03080 1.2e-51 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IPEPIGIO_03081 3.9e-136 L Replication protein
IPEPIGIO_03082 2.6e-123 L Transposase and inactivated derivatives, IS30 family
IPEPIGIO_03083 6.6e-88 terC P integral membrane protein, YkoY family
IPEPIGIO_03084 5e-27 terC P integral membrane protein, YkoY family
IPEPIGIO_03085 7e-141
IPEPIGIO_03086 4.2e-145 glpQ 3.1.4.46 C phosphodiesterase
IPEPIGIO_03087 8.3e-162 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
IPEPIGIO_03088 8.4e-57 D Alpha beta
IPEPIGIO_03089 3.1e-130 L Helix-turn-helix domain
IPEPIGIO_03090 1.7e-159 L hmm pf00665

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)