ORF_ID e_value Gene_name EC_number CAZy COGs Description
IAFFMICD_00001 7.9e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
IAFFMICD_00002 3.6e-168 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
IAFFMICD_00003 5.6e-147 gntR K rpiR family
IAFFMICD_00004 1.9e-169 iolH G Xylose isomerase-like TIM barrel
IAFFMICD_00005 4.8e-157 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
IAFFMICD_00006 1.7e-66 iolK S Tautomerase enzyme
IAFFMICD_00007 6.2e-157 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
IAFFMICD_00008 1.2e-174 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IAFFMICD_00009 1.8e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
IAFFMICD_00010 7.1e-192 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IAFFMICD_00011 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IAFFMICD_00012 5.4e-178 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IAFFMICD_00013 6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IAFFMICD_00014 9.5e-275 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
IAFFMICD_00015 1.9e-267 iolT EGP Major facilitator Superfamily
IAFFMICD_00016 7.4e-141 iolR K DeoR C terminal sensor domain
IAFFMICD_00017 1.1e-163 yvgN C Aldo keto reductase
IAFFMICD_00018 2.7e-140 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IAFFMICD_00019 1e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAFFMICD_00020 1.2e-85 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IAFFMICD_00021 5.3e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IAFFMICD_00022 1.2e-219 hpk31 2.7.13.3 T Histidine kinase
IAFFMICD_00023 2.5e-121 K response regulator
IAFFMICD_00024 1.7e-117
IAFFMICD_00025 5.1e-268 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IAFFMICD_00026 7.3e-141 XK27_01040 S Protein of unknown function (DUF1129)
IAFFMICD_00027 1.5e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IAFFMICD_00028 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
IAFFMICD_00029 2e-155 spo0J K Belongs to the ParB family
IAFFMICD_00030 7.4e-138 soj D Sporulation initiation inhibitor
IAFFMICD_00031 2.4e-142 noc K Belongs to the ParB family
IAFFMICD_00032 2.8e-134 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IAFFMICD_00033 3.7e-66
IAFFMICD_00034 1e-127 cobQ S glutamine amidotransferase
IAFFMICD_00036 5.7e-104 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IAFFMICD_00037 8.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IAFFMICD_00038 5.2e-146 S Protein of unknown function (DUF979)
IAFFMICD_00039 6e-115 S Protein of unknown function (DUF969)
IAFFMICD_00040 2.4e-129 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IAFFMICD_00041 7.9e-65 asp2 S Asp23 family, cell envelope-related function
IAFFMICD_00042 5.1e-61 asp23 S Asp23 family, cell envelope-related function
IAFFMICD_00043 2.5e-29
IAFFMICD_00044 5.8e-89 S Protein conserved in bacteria
IAFFMICD_00045 6.4e-38 S Transglycosylase associated protein
IAFFMICD_00046 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
IAFFMICD_00047 3.2e-27 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFFMICD_00048 2.2e-102 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFFMICD_00049 6.7e-27
IAFFMICD_00050 3.4e-36
IAFFMICD_00051 2.7e-82 fld C Flavodoxin
IAFFMICD_00052 2.1e-51
IAFFMICD_00053 1.1e-64
IAFFMICD_00055 1e-55 ywjH S Protein of unknown function (DUF1634)
IAFFMICD_00056 4e-129 yxaA S Sulfite exporter TauE/SafE
IAFFMICD_00057 5.1e-210 S TPM domain
IAFFMICD_00058 1.7e-116
IAFFMICD_00059 9.4e-261 nox 1.6.3.4 C NADH oxidase
IAFFMICD_00060 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
IAFFMICD_00061 3e-212 S nuclear-transcribed mRNA catabolic process, no-go decay
IAFFMICD_00062 2.5e-80 S NUDIX domain
IAFFMICD_00063 1.6e-74
IAFFMICD_00064 2.5e-118 V ATPases associated with a variety of cellular activities
IAFFMICD_00065 2e-116
IAFFMICD_00066 8.6e-117
IAFFMICD_00067 6.3e-76
IAFFMICD_00068 6.9e-303 oppA E ABC transporter, substratebinding protein
IAFFMICD_00069 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IAFFMICD_00071 1.3e-16
IAFFMICD_00072 6.6e-47 V ATPase activity
IAFFMICD_00074 3e-89
IAFFMICD_00077 5.7e-248 bmr3 EGP Major facilitator Superfamily
IAFFMICD_00078 1e-136 magIII L Base excision DNA repair protein, HhH-GPD family
IAFFMICD_00079 1.3e-159 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
IAFFMICD_00080 7.3e-242 sgaT 2.7.1.194 S PTS system sugar-specific permease component
IAFFMICD_00081 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IAFFMICD_00082 2.1e-285 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
IAFFMICD_00083 3.2e-133 K DeoR C terminal sensor domain
IAFFMICD_00084 1.2e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAFFMICD_00085 2.7e-252 rarA L recombination factor protein RarA
IAFFMICD_00086 7.4e-55
IAFFMICD_00087 3.7e-150 yhaI S Protein of unknown function (DUF805)
IAFFMICD_00088 3.8e-271 L Mga helix-turn-helix domain
IAFFMICD_00090 1.3e-183 ynjC S Cell surface protein
IAFFMICD_00091 1.1e-123 yqcC S WxL domain surface cell wall-binding
IAFFMICD_00093 0.0
IAFFMICD_00094 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAFFMICD_00095 1e-42
IAFFMICD_00096 5.8e-188 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAFFMICD_00097 9e-53 S DsrE/DsrF-like family
IAFFMICD_00098 1.4e-254 pbuO S permease
IAFFMICD_00099 5.2e-54 S Protein of unknown function (DUF1516)
IAFFMICD_00100 2.4e-57 ypaA S Protein of unknown function (DUF1304)
IAFFMICD_00101 5.6e-41
IAFFMICD_00102 4.9e-131 K UTRA
IAFFMICD_00103 2.3e-286 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_00104 1.6e-252 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAFFMICD_00105 8e-85
IAFFMICD_00106 5.8e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IAFFMICD_00107 2.9e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_00108 1.4e-189 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFFMICD_00109 4.3e-91 ogt 2.1.1.63 L Methyltransferase
IAFFMICD_00110 1.6e-120 K Transcriptional regulatory protein, C terminal
IAFFMICD_00111 1.5e-200 T PhoQ Sensor
IAFFMICD_00112 9.7e-86
IAFFMICD_00113 7.8e-226 EGP Major facilitator Superfamily
IAFFMICD_00114 3.8e-111
IAFFMICD_00115 2.1e-39
IAFFMICD_00116 1.1e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IAFFMICD_00117 7.3e-42
IAFFMICD_00118 1.2e-207 mccF V LD-carboxypeptidase
IAFFMICD_00119 4.8e-182 yveB 2.7.4.29 I PAP2 superfamily
IAFFMICD_00120 3e-111 K Bacteriophage CI repressor helix-turn-helix domain
IAFFMICD_00121 7.7e-51
IAFFMICD_00122 9.7e-30
IAFFMICD_00123 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IAFFMICD_00124 1.2e-103 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IAFFMICD_00125 6.5e-120 yxlF V ABC transporter
IAFFMICD_00126 1.6e-26 S Phospholipase_D-nuclease N-terminal
IAFFMICD_00127 5.3e-153 K Helix-turn-helix XRE-family like proteins
IAFFMICD_00128 5.5e-204 yxaM EGP Major facilitator Superfamily
IAFFMICD_00129 1.3e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
IAFFMICD_00130 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
IAFFMICD_00132 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAFFMICD_00133 6.7e-206 4.1.1.52 S Amidohydrolase
IAFFMICD_00134 0.0 ylbB V ABC transporter permease
IAFFMICD_00135 5.4e-127 V ABC transporter, ATP-binding protein
IAFFMICD_00136 4.5e-106 K Transcriptional regulator C-terminal region
IAFFMICD_00137 7.5e-155 K Helix-turn-helix domain, rpiR family
IAFFMICD_00138 6.6e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
IAFFMICD_00139 1.5e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IAFFMICD_00140 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IAFFMICD_00141 6.2e-128
IAFFMICD_00142 9.9e-83
IAFFMICD_00143 1.7e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IAFFMICD_00144 5.1e-70 rplI J Binds to the 23S rRNA
IAFFMICD_00145 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IAFFMICD_00146 7.5e-100 V ABC transporter, ATP-binding protein
IAFFMICD_00147 6.8e-80 P ABC-2 family transporter protein
IAFFMICD_00148 1.5e-55 V ABC-2 type transporter
IAFFMICD_00149 2.1e-61 K Tetracyclin repressor, C-terminal all-alpha domain
IAFFMICD_00150 1.4e-105 L PFAM transposase, IS4 family protein
IAFFMICD_00151 2.1e-51 L PFAM transposase, IS4 family protein
IAFFMICD_00153 1.1e-150 EG EamA-like transporter family
IAFFMICD_00154 5e-72 3.6.1.55 L NUDIX domain
IAFFMICD_00155 2.1e-61
IAFFMICD_00156 9.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAFFMICD_00157 5.6e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IAFFMICD_00158 4.4e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
IAFFMICD_00159 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IAFFMICD_00160 7.7e-73 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IAFFMICD_00161 4.9e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IAFFMICD_00162 2.1e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAFFMICD_00163 7.7e-135 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IAFFMICD_00164 4.4e-106 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
IAFFMICD_00165 1.7e-53
IAFFMICD_00166 2.1e-99 V ATPases associated with a variety of cellular activities
IAFFMICD_00167 1.3e-109
IAFFMICD_00168 8e-158 S ABC-type transport system involved in multi-copper enzyme maturation permease component
IAFFMICD_00169 4.3e-116
IAFFMICD_00170 8.8e-110 K Bacterial regulatory proteins, tetR family
IAFFMICD_00171 1.5e-301 norB EGP Major Facilitator
IAFFMICD_00173 3.2e-181 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAFFMICD_00174 6.7e-99 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IAFFMICD_00175 5.6e-42 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IAFFMICD_00176 2.6e-36 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IAFFMICD_00177 5.5e-228 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IAFFMICD_00178 5.2e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IAFFMICD_00180 4.8e-157 bglK_1 2.7.1.2 GK ROK family
IAFFMICD_00181 4.6e-254 bgl 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_00182 3.1e-139 K SIS domain
IAFFMICD_00183 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
IAFFMICD_00184 1.6e-79 frvA 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_00185 2.2e-250 manY 2.7.1.191, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_00186 1.8e-156 S CAAX protease self-immunity
IAFFMICD_00188 3.1e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IAFFMICD_00189 3.6e-100 dps P Belongs to the Dps family
IAFFMICD_00190 5.6e-33 copZ P Heavy-metal-associated domain
IAFFMICD_00191 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
IAFFMICD_00192 1.2e-214 opuCA E ABC transporter, ATP-binding protein
IAFFMICD_00193 4.7e-106 opuCB E ABC transporter permease
IAFFMICD_00194 1.6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IAFFMICD_00195 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
IAFFMICD_00197 1e-148 S Protein of unknown function (DUF3100)
IAFFMICD_00198 1.9e-69 S An automated process has identified a potential problem with this gene model
IAFFMICD_00199 7.6e-244 3.5.4.28, 3.5.4.31 F Amidohydrolase family
IAFFMICD_00200 4.3e-122 S Sulfite exporter TauE/SafE
IAFFMICD_00201 1e-105 K Tetracycline repressor, C-terminal all-alpha domain
IAFFMICD_00202 0.0 ydgH S MMPL family
IAFFMICD_00204 1.5e-118 K Bacterial regulatory proteins, tetR family
IAFFMICD_00205 2e-219 3.1.1.83 I Alpha beta hydrolase
IAFFMICD_00206 1.3e-241 EGP Major facilitator Superfamily
IAFFMICD_00207 1e-64 S pyridoxamine 5-phosphate
IAFFMICD_00208 1.6e-57
IAFFMICD_00209 0.0 M Glycosyl hydrolase family 59
IAFFMICD_00210 4.3e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
IAFFMICD_00211 1.2e-126 kdgR K FCD domain
IAFFMICD_00212 1.8e-229 G Major Facilitator
IAFFMICD_00213 7.8e-267 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
IAFFMICD_00214 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
IAFFMICD_00215 3.3e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IAFFMICD_00216 9.5e-280 uxaC 5.3.1.12 G glucuronate isomerase
IAFFMICD_00217 4.6e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
IAFFMICD_00218 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
IAFFMICD_00219 0.0 M Glycosyl hydrolase family 59
IAFFMICD_00220 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
IAFFMICD_00221 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
IAFFMICD_00222 2.4e-122 azlC E branched-chain amino acid
IAFFMICD_00223 6.1e-244 ybfG M peptidoglycan-binding domain-containing protein
IAFFMICD_00225 5.9e-53
IAFFMICD_00226 2.1e-86
IAFFMICD_00227 6.1e-106 S Membrane
IAFFMICD_00228 1.5e-285 pipD E Dipeptidase
IAFFMICD_00230 8.5e-54
IAFFMICD_00231 5e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IAFFMICD_00232 2.1e-103 S Protein of unknown function (DUF1211)
IAFFMICD_00233 4.1e-128 S membrane transporter protein
IAFFMICD_00234 1.4e-45
IAFFMICD_00235 1.9e-152 supH G Sucrose-6F-phosphate phosphohydrolase
IAFFMICD_00236 5e-96 K transcriptional regulator
IAFFMICD_00237 6.3e-128 macB V ABC transporter, ATP-binding protein
IAFFMICD_00238 0.0 ylbB V ABC transporter permease
IAFFMICD_00239 4e-125 usp 3.5.1.28 CBM50 D CHAP domain
IAFFMICD_00240 8.6e-212 P Pyridine nucleotide-disulphide oxidoreductase
IAFFMICD_00241 4.5e-189 amtB P Ammonium Transporter Family
IAFFMICD_00242 1.1e-161 V ABC transporter
IAFFMICD_00243 6e-84 V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
IAFFMICD_00244 9.2e-108 S CAAX protease self-immunity
IAFFMICD_00245 2.1e-28
IAFFMICD_00246 1e-182 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
IAFFMICD_00247 2.9e-279 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
IAFFMICD_00248 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
IAFFMICD_00249 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAFFMICD_00250 7.3e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IAFFMICD_00251 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IAFFMICD_00252 4.2e-74 ssb_2 L Single-strand binding protein family
IAFFMICD_00254 1.8e-15
IAFFMICD_00257 4.7e-08 ssb_2 L Single-strand binding protein family
IAFFMICD_00258 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAFFMICD_00259 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAFFMICD_00260 7.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAFFMICD_00261 2.9e-31 yaaA S S4 domain protein YaaA
IAFFMICD_00263 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IAFFMICD_00264 3.5e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAFFMICD_00265 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IAFFMICD_00268 7.1e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IAFFMICD_00269 6.4e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IAFFMICD_00270 1.3e-137 jag S R3H domain protein
IAFFMICD_00271 3.6e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IAFFMICD_00272 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IAFFMICD_00273 2.3e-274 V ABC transporter transmembrane region
IAFFMICD_00274 7.2e-30
IAFFMICD_00276 3.2e-133 thrE S Putative threonine/serine exporter
IAFFMICD_00277 2.6e-80 S Threonine/Serine exporter, ThrE
IAFFMICD_00278 2e-222 amd 3.5.1.47 E Peptidase family M20/M25/M40
IAFFMICD_00281 5.8e-197 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
IAFFMICD_00282 2.8e-60 K Psort location Cytoplasmic, score
IAFFMICD_00285 2.7e-149 M NLPA lipoprotein
IAFFMICD_00286 1.4e-139 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IAFFMICD_00287 1.1e-222 mtnE 2.6.1.83 E Aminotransferase
IAFFMICD_00288 1.5e-232 M Leucine rich repeats (6 copies)
IAFFMICD_00289 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_00290 1.3e-168 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
IAFFMICD_00291 1.5e-130 rpl K Helix-turn-helix domain, rpiR family
IAFFMICD_00292 1.8e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAFFMICD_00293 5.7e-288 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
IAFFMICD_00294 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IAFFMICD_00295 5.6e-245 P Sodium:sulfate symporter transmembrane region
IAFFMICD_00296 5.8e-158 K LysR substrate binding domain
IAFFMICD_00297 1.3e-75
IAFFMICD_00298 9e-72 K Transcriptional regulator
IAFFMICD_00299 1.5e-245 ypiB EGP Major facilitator Superfamily
IAFFMICD_00300 7.8e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
IAFFMICD_00302 4.3e-241 pts36C G PTS system sugar-specific permease component
IAFFMICD_00303 1.1e-50 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_00304 3e-68 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_00305 1.2e-119 K DeoR C terminal sensor domain
IAFFMICD_00307 4.4e-166 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IAFFMICD_00308 1.4e-258 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
IAFFMICD_00309 3.8e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
IAFFMICD_00310 4.5e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IAFFMICD_00311 8.8e-227 iolF EGP Major facilitator Superfamily
IAFFMICD_00312 4.1e-192 rhaR K helix_turn_helix, arabinose operon control protein
IAFFMICD_00313 6.4e-215 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
IAFFMICD_00314 1.4e-65 S Protein of unknown function (DUF1093)
IAFFMICD_00315 1.3e-120
IAFFMICD_00316 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IAFFMICD_00317 4.6e-305 plyA3 M Right handed beta helix region
IAFFMICD_00318 2.9e-81
IAFFMICD_00319 1.2e-269 M Heparinase II/III N-terminus
IAFFMICD_00321 3.5e-66 G PTS system fructose IIA component
IAFFMICD_00322 3.6e-143 agaD G PTS system mannose/fructose/sorbose family IID component
IAFFMICD_00323 6.4e-132 G PTS system sorbose-specific iic component
IAFFMICD_00324 3.5e-80 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
IAFFMICD_00325 8.3e-205 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
IAFFMICD_00326 8.4e-103 Z012_03480 S Psort location Cytoplasmic, score
IAFFMICD_00327 1.9e-109 K Bacterial transcriptional regulator
IAFFMICD_00328 1.7e-143 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IAFFMICD_00329 1e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAFFMICD_00330 2.3e-87 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
IAFFMICD_00331 1.8e-152 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
IAFFMICD_00332 8.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAFFMICD_00333 0.0 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
IAFFMICD_00334 8.7e-205 rafA 3.2.1.22 G Melibiase
IAFFMICD_00335 1.3e-39 2.7.1.191 G PTS system sorbose subfamily IIB component
IAFFMICD_00336 3.1e-65 G PTS system mannose/fructose/sorbose family IID component
IAFFMICD_00337 4.4e-64 G PTS system sorbose-specific iic component
IAFFMICD_00338 2.7e-22 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IAFFMICD_00339 4.6e-53 araR K Transcriptional regulator
IAFFMICD_00340 7.8e-271 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
IAFFMICD_00341 3.6e-296 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
IAFFMICD_00342 8.3e-208 V ABC-type multidrug transport system, ATPase and permease components
IAFFMICD_00343 6.9e-108 K Transcriptional activator, Rgg GadR MutR family
IAFFMICD_00344 7e-125 K Helix-turn-helix domain, rpiR family
IAFFMICD_00345 5.2e-60 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IAFFMICD_00346 1.1e-10 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IAFFMICD_00348 3.7e-137 4.1.2.14 S KDGP aldolase
IAFFMICD_00349 1.2e-202 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
IAFFMICD_00350 2.2e-215 dho 3.5.2.3 S Amidohydrolase family
IAFFMICD_00351 1e-106 S Domain of unknown function (DUF4310)
IAFFMICD_00352 1.7e-137 S Domain of unknown function (DUF4311)
IAFFMICD_00353 1.7e-52 S Domain of unknown function (DUF4312)
IAFFMICD_00354 1.2e-61 S Glycine-rich SFCGS
IAFFMICD_00355 1.5e-53 S PRD domain
IAFFMICD_00356 0.0 K Mga helix-turn-helix domain
IAFFMICD_00357 2.9e-122 tal 2.2.1.2 H Pfam:Transaldolase
IAFFMICD_00358 3.9e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IAFFMICD_00359 2.8e-194 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
IAFFMICD_00360 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
IAFFMICD_00361 1.4e-87 gutM K Glucitol operon activator protein (GutM)
IAFFMICD_00362 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
IAFFMICD_00363 2.5e-144 IQ NAD dependent epimerase/dehydratase family
IAFFMICD_00364 2.5e-24 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IAFFMICD_00365 1.5e-29 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
IAFFMICD_00366 1.6e-137 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IAFFMICD_00367 5.3e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
IAFFMICD_00368 5.4e-167 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
IAFFMICD_00369 8.3e-137 repA K DeoR C terminal sensor domain
IAFFMICD_00370 1.6e-114 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
IAFFMICD_00371 1.4e-44 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_00372 4.5e-280 ulaA S PTS system sugar-specific permease component
IAFFMICD_00373 3.6e-79 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_00374 1.2e-213 ulaG S Beta-lactamase superfamily domain
IAFFMICD_00375 0.0 O Belongs to the peptidase S8 family
IAFFMICD_00376 2.6e-42
IAFFMICD_00377 1.6e-155 bglK_1 GK ROK family
IAFFMICD_00378 1.1e-178 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
IAFFMICD_00379 4.1e-245 3.5.1.18 E Peptidase family M20/M25/M40
IAFFMICD_00380 1.2e-129 ymfC K UTRA
IAFFMICD_00381 5.3e-215 uhpT EGP Major facilitator Superfamily
IAFFMICD_00382 4.7e-204 3.2.1.51 GH29 G Alpha-L-fucosidase
IAFFMICD_00383 7.6e-91 yjgM K Acetyltransferase (GNAT) domain
IAFFMICD_00384 3.7e-111 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
IAFFMICD_00386 2.8e-97 K Helix-turn-helix domain
IAFFMICD_00387 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
IAFFMICD_00388 9.6e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
IAFFMICD_00389 9.9e-108 pncA Q Isochorismatase family
IAFFMICD_00390 9.5e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAFFMICD_00391 3.6e-131 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IAFFMICD_00392 3.3e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAFFMICD_00393 6.4e-241 ugpB G Bacterial extracellular solute-binding protein
IAFFMICD_00394 2.2e-148 ugpE G ABC transporter permease
IAFFMICD_00395 4.7e-163 ugpA P ABC-type sugar transport systems, permease components
IAFFMICD_00396 9.5e-211 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
IAFFMICD_00397 5.1e-224 EGP Major facilitator Superfamily
IAFFMICD_00398 1.5e-146 3.5.2.6 V Beta-lactamase enzyme family
IAFFMICD_00399 4.5e-191 blaA6 V Beta-lactamase
IAFFMICD_00400 2.9e-146 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IAFFMICD_00401 6.9e-162 ybbH_2 K Helix-turn-helix domain, rpiR family
IAFFMICD_00402 7.6e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
IAFFMICD_00403 2.4e-150 G PTS system mannose/fructose/sorbose family IID component
IAFFMICD_00404 1.8e-129 G PTS system sorbose-specific iic component
IAFFMICD_00406 2.7e-202 S endonuclease exonuclease phosphatase family protein
IAFFMICD_00407 1.5e-172 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IAFFMICD_00408 8.5e-159 1.1.1.346 S reductase
IAFFMICD_00409 2.5e-74 adhR K helix_turn_helix, mercury resistance
IAFFMICD_00410 3.7e-142 Q Methyltransferase
IAFFMICD_00411 9.1e-50 sugE U Multidrug resistance protein
IAFFMICD_00413 1.2e-145 V ABC transporter transmembrane region
IAFFMICD_00414 1e-56
IAFFMICD_00415 5.9e-36
IAFFMICD_00416 6.5e-108 S alpha beta
IAFFMICD_00417 6.6e-79 MA20_25245 K FR47-like protein
IAFFMICD_00418 1.7e-77 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
IAFFMICD_00419 2.7e-132 wzb 3.1.3.48 T Tyrosine phosphatase family
IAFFMICD_00420 3.5e-85 K Acetyltransferase (GNAT) domain
IAFFMICD_00421 1.3e-122
IAFFMICD_00422 1.2e-66 6.3.3.2 S ASCH
IAFFMICD_00423 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IAFFMICD_00424 4.1e-198 ybiR P Citrate transporter
IAFFMICD_00425 6.8e-100
IAFFMICD_00426 7.3e-250 E Peptidase dimerisation domain
IAFFMICD_00427 2.5e-297 E ABC transporter, substratebinding protein
IAFFMICD_00428 1.3e-133
IAFFMICD_00429 0.0 K helix_turn_helix, arabinose operon control protein
IAFFMICD_00430 3.9e-282 G MFS/sugar transport protein
IAFFMICD_00431 0.0 S Glycosyl hydrolase family 115
IAFFMICD_00432 7.6e-300 cadA P P-type ATPase
IAFFMICD_00433 2.7e-76 hsp3 O Hsp20/alpha crystallin family
IAFFMICD_00434 5.9e-70 S Iron-sulphur cluster biosynthesis
IAFFMICD_00435 2.9e-206 htrA 3.4.21.107 O serine protease
IAFFMICD_00436 2.7e-154 vicX 3.1.26.11 S domain protein
IAFFMICD_00437 4.4e-141 yycI S YycH protein
IAFFMICD_00438 1.8e-259 yycH S YycH protein
IAFFMICD_00439 0.0 vicK 2.7.13.3 T Histidine kinase
IAFFMICD_00440 8.1e-131 K response regulator
IAFFMICD_00441 2.7e-123 S Alpha/beta hydrolase family
IAFFMICD_00442 9.3e-259 arpJ P ABC transporter permease
IAFFMICD_00443 8.8e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IAFFMICD_00444 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
IAFFMICD_00445 7e-214 S Bacterial protein of unknown function (DUF871)
IAFFMICD_00446 1.2e-73 S Domain of unknown function (DUF3284)
IAFFMICD_00447 3.8e-238 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAFFMICD_00448 6.9e-130 K UbiC transcription regulator-associated domain protein
IAFFMICD_00449 3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_00450 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
IAFFMICD_00451 1.7e-107 speG J Acetyltransferase (GNAT) domain
IAFFMICD_00452 2.2e-81 F NUDIX domain
IAFFMICD_00453 2.5e-89 S AAA domain
IAFFMICD_00454 2.3e-113 ycaC Q Isochorismatase family
IAFFMICD_00455 1.6e-77 ydiC1 EGP Major Facilitator Superfamily
IAFFMICD_00456 1e-157 ydiC1 EGP Major Facilitator Superfamily
IAFFMICD_00457 4.1e-212 yeaN P Transporter, major facilitator family protein
IAFFMICD_00458 5e-173 iolS C Aldo keto reductase
IAFFMICD_00459 4.4e-64 manO S Domain of unknown function (DUF956)
IAFFMICD_00460 8.7e-170 manN G system, mannose fructose sorbose family IID component
IAFFMICD_00461 1.6e-122 manY G PTS system
IAFFMICD_00462 2.1e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IAFFMICD_00463 9.8e-220 EGP Major facilitator Superfamily
IAFFMICD_00464 1e-187 K Helix-turn-helix XRE-family like proteins
IAFFMICD_00465 2.3e-148 K Helix-turn-helix XRE-family like proteins
IAFFMICD_00466 9.6e-158 K sequence-specific DNA binding
IAFFMICD_00471 0.0 ybfG M peptidoglycan-binding domain-containing protein
IAFFMICD_00473 4e-287 glnP P ABC transporter permease
IAFFMICD_00474 2.4e-133 glnQ E ABC transporter, ATP-binding protein
IAFFMICD_00475 1.7e-39
IAFFMICD_00476 2e-236 malE G Bacterial extracellular solute-binding protein
IAFFMICD_00477 9.1e-16
IAFFMICD_00478 4.8e-131 S Protein of unknown function (DUF975)
IAFFMICD_00479 1.5e-58 yqkB S Iron-sulphur cluster biosynthesis
IAFFMICD_00480 1.2e-52
IAFFMICD_00481 1.9e-80 S Bacterial PH domain
IAFFMICD_00482 1.4e-284 ydbT S Bacterial PH domain
IAFFMICD_00483 3.8e-142 S AAA ATPase domain
IAFFMICD_00484 4.3e-166 yniA G Phosphotransferase enzyme family
IAFFMICD_00485 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAFFMICD_00486 2.1e-255 glnP P ABC transporter
IAFFMICD_00487 3.3e-264 glnP P ABC transporter
IAFFMICD_00488 8.3e-99 ydaF J Acetyltransferase (GNAT) domain
IAFFMICD_00489 9.7e-104 S Stage II sporulation protein M
IAFFMICD_00490 6.4e-168 yeaC S ATPase family associated with various cellular activities (AAA)
IAFFMICD_00491 7.1e-133 yeaD S Protein of unknown function DUF58
IAFFMICD_00492 0.0 yebA E Transglutaminase/protease-like homologues
IAFFMICD_00493 7e-214 lsgC M Glycosyl transferases group 1
IAFFMICD_00494 4.6e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
IAFFMICD_00497 6.3e-197 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IAFFMICD_00498 2.9e-222 maeN C 2-hydroxycarboxylate transporter family
IAFFMICD_00499 1.8e-268 dcuS 2.7.13.3 T Single cache domain 3
IAFFMICD_00500 4.1e-119 dpiA KT cheY-homologous receiver domain
IAFFMICD_00501 5.5e-95
IAFFMICD_00502 3.7e-118 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFFMICD_00504 1.8e-148 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
IAFFMICD_00505 1.4e-68
IAFFMICD_00506 1.6e-131 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
IAFFMICD_00507 5.8e-169 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAFFMICD_00509 8.8e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAFFMICD_00510 1.5e-180 D Alpha beta
IAFFMICD_00511 5.9e-185 lipA I Carboxylesterase family
IAFFMICD_00512 3.5e-216 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
IAFFMICD_00513 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAFFMICD_00514 0.0 mtlR K Mga helix-turn-helix domain
IAFFMICD_00515 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_00516 2.8e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IAFFMICD_00517 3.3e-149 S haloacid dehalogenase-like hydrolase
IAFFMICD_00518 2.8e-44
IAFFMICD_00519 2e-14
IAFFMICD_00520 4.1e-136
IAFFMICD_00521 4.4e-222 spiA K IrrE N-terminal-like domain
IAFFMICD_00522 3.7e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAFFMICD_00523 2e-126 V ABC transporter
IAFFMICD_00524 8.1e-208 bacI V MacB-like periplasmic core domain
IAFFMICD_00525 1.1e-90 1.6.5.5 C nadph quinone reductase
IAFFMICD_00526 3.6e-74 K Helix-turn-helix XRE-family like proteins
IAFFMICD_00527 6.4e-30
IAFFMICD_00528 1.1e-180
IAFFMICD_00529 0.0 M Leucine rich repeats (6 copies)
IAFFMICD_00530 6.2e-51 S MazG-like family
IAFFMICD_00531 0.0 FbpA K Fibronectin-binding protein
IAFFMICD_00532 8.1e-09
IAFFMICD_00533 3.2e-161 degV S EDD domain protein, DegV family
IAFFMICD_00534 1.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
IAFFMICD_00535 2.2e-204 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
IAFFMICD_00536 9.2e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IAFFMICD_00537 2.7e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IAFFMICD_00538 2.9e-34 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAFFMICD_00539 5.2e-176 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAFFMICD_00540 2.4e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IAFFMICD_00541 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAFFMICD_00542 4.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IAFFMICD_00543 3.2e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IAFFMICD_00544 2.1e-57 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAFFMICD_00545 6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IAFFMICD_00546 3.1e-206 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAFFMICD_00547 1.3e-145 Q Fumarylacetoacetate (FAA) hydrolase family
IAFFMICD_00548 2.6e-112 nfnB 1.5.1.34 C Nitroreductase family
IAFFMICD_00549 5.9e-70 K Acetyltransferase (GNAT) domain
IAFFMICD_00550 7.1e-68 msi198 K Acetyltransferase (GNAT) domain
IAFFMICD_00551 1.1e-217 EGP Transmembrane secretion effector
IAFFMICD_00552 4.8e-128 T Transcriptional regulatory protein, C terminal
IAFFMICD_00553 5.2e-173 T Histidine kinase-like ATPases
IAFFMICD_00554 3.8e-134 XK27_05695 V ABC transporter, ATP-binding protein
IAFFMICD_00555 0.0 ysaB V FtsX-like permease family
IAFFMICD_00556 2.9e-207 xerS L Belongs to the 'phage' integrase family
IAFFMICD_00557 9.5e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
IAFFMICD_00558 2.5e-169 K LysR substrate binding domain
IAFFMICD_00559 4.3e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAFFMICD_00560 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
IAFFMICD_00561 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IAFFMICD_00562 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IAFFMICD_00563 4.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IAFFMICD_00564 6.2e-173 lacX 5.1.3.3 G Aldose 1-epimerase
IAFFMICD_00565 5e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IAFFMICD_00566 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IAFFMICD_00567 1.5e-166 xerC D Belongs to the 'phage' integrase family. XerC subfamily
IAFFMICD_00568 3e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IAFFMICD_00569 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAFFMICD_00570 1.4e-147 dprA LU DNA protecting protein DprA
IAFFMICD_00571 3.6e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAFFMICD_00572 1.8e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IAFFMICD_00573 4.8e-131 S Domain of unknown function (DUF4918)
IAFFMICD_00576 7.2e-74 S Psort location Cytoplasmic, score
IAFFMICD_00578 3e-257 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IAFFMICD_00579 2.3e-40 yozE S Belongs to the UPF0346 family
IAFFMICD_00580 1.5e-85 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAFFMICD_00581 5.8e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IAFFMICD_00582 7.8e-157 ypmR E GDSL-like Lipase/Acylhydrolase
IAFFMICD_00583 1.5e-147 DegV S EDD domain protein, DegV family
IAFFMICD_00584 2.1e-114 hly S protein, hemolysin III
IAFFMICD_00585 7.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAFFMICD_00586 4.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IAFFMICD_00587 0.0 yfmR S ABC transporter, ATP-binding protein
IAFFMICD_00588 9.6e-85
IAFFMICD_00589 2.4e-192 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IAFFMICD_00590 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAFFMICD_00591 3.5e-233 S Tetratricopeptide repeat protein
IAFFMICD_00592 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IAFFMICD_00593 1.7e-204 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IAFFMICD_00594 3.9e-32 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IAFFMICD_00595 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
IAFFMICD_00596 2.6e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IAFFMICD_00597 3.8e-55 M Lysin motif
IAFFMICD_00598 1.3e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IAFFMICD_00599 1e-179 ypbB 5.1.3.1 S Helix-turn-helix domain
IAFFMICD_00600 1.4e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
IAFFMICD_00601 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IAFFMICD_00602 9.4e-138 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IAFFMICD_00603 3.3e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAFFMICD_00604 7.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAFFMICD_00605 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IAFFMICD_00606 3.3e-166 xerD D recombinase XerD
IAFFMICD_00607 3.4e-163 cvfB S S1 domain
IAFFMICD_00608 7.2e-72 yeaL S Protein of unknown function (DUF441)
IAFFMICD_00609 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IAFFMICD_00610 3.5e-177 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IAFFMICD_00611 0.0 dnaE 2.7.7.7 L DNA polymerase
IAFFMICD_00612 1.7e-172 dnaE 2.7.7.7 L DNA polymerase
IAFFMICD_00613 6e-20 S Protein of unknown function (DUF2929)
IAFFMICD_00614 1.2e-144
IAFFMICD_00615 1.7e-298 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
IAFFMICD_00616 9.6e-95 M1-874 K Domain of unknown function (DUF1836)
IAFFMICD_00617 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IAFFMICD_00618 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IAFFMICD_00619 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
IAFFMICD_00620 4.3e-141 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
IAFFMICD_00621 9.4e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IAFFMICD_00622 0.0 oatA I Acyltransferase
IAFFMICD_00623 1.9e-234 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IAFFMICD_00624 7.7e-132 fruR K DeoR C terminal sensor domain
IAFFMICD_00625 2.7e-155 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IAFFMICD_00626 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
IAFFMICD_00627 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IAFFMICD_00628 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAFFMICD_00629 1.5e-259 glnPH2 P ABC transporter permease
IAFFMICD_00630 2.3e-20
IAFFMICD_00631 1e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IAFFMICD_00632 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
IAFFMICD_00633 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IAFFMICD_00634 3.2e-197 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IAFFMICD_00635 2.6e-311 yknV V ABC transporter
IAFFMICD_00636 9.3e-65 rmeD K helix_turn_helix, mercury resistance
IAFFMICD_00637 1.7e-63 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
IAFFMICD_00638 6.2e-134 cobB K Sir2 family
IAFFMICD_00639 2.2e-82 M Protein of unknown function (DUF3737)
IAFFMICD_00640 9.2e-212 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAFFMICD_00641 1.6e-160 S Tetratricopeptide repeat
IAFFMICD_00642 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAFFMICD_00643 2.2e-117
IAFFMICD_00644 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAFFMICD_00645 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
IAFFMICD_00646 1.4e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
IAFFMICD_00647 0.0 comEC S Competence protein ComEC
IAFFMICD_00648 2.6e-107 comEA L Competence protein ComEA
IAFFMICD_00649 3e-193 ylbL T Belongs to the peptidase S16 family
IAFFMICD_00650 2.8e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IAFFMICD_00651 1.7e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IAFFMICD_00652 3.8e-57 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IAFFMICD_00653 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IAFFMICD_00654 8.5e-210 ftsW D Belongs to the SEDS family
IAFFMICD_00655 0.0 typA T GTP-binding protein TypA
IAFFMICD_00656 5e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IAFFMICD_00657 1.4e-46 yktA S Belongs to the UPF0223 family
IAFFMICD_00658 8.3e-157 1.1.1.27 C L-malate dehydrogenase activity
IAFFMICD_00659 2.4e-259 lpdA 1.8.1.4 C Dehydrogenase
IAFFMICD_00660 3.7e-243 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IAFFMICD_00661 3.1e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IAFFMICD_00662 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IAFFMICD_00663 1.8e-111 S E1-E2 ATPase
IAFFMICD_00664 1.4e-08 S E1-E2 ATPase
IAFFMICD_00665 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IAFFMICD_00666 1.9e-25
IAFFMICD_00667 1.7e-73
IAFFMICD_00669 4.9e-31 ykzG S Belongs to the UPF0356 family
IAFFMICD_00670 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAFFMICD_00671 6.5e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IAFFMICD_00672 2.1e-243 els S Sterol carrier protein domain
IAFFMICD_00673 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IAFFMICD_00674 7e-116 S Repeat protein
IAFFMICD_00675 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IAFFMICD_00676 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IAFFMICD_00677 0.0 uvrA2 L ABC transporter
IAFFMICD_00678 2.6e-58 XK27_04120 S Putative amino acid metabolism
IAFFMICD_00679 2.9e-159 iscS 2.8.1.7 E Aminotransferase class V
IAFFMICD_00680 2e-227 bdhA C Iron-containing alcohol dehydrogenase
IAFFMICD_00681 7.1e-62 P Rhodanese-like domain
IAFFMICD_00682 5.7e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
IAFFMICD_00683 3.5e-80 2.7.7.65 T diguanylate cyclase activity
IAFFMICD_00684 5.3e-202 ydaN S Bacterial cellulose synthase subunit
IAFFMICD_00685 1.6e-182 ydaM M Glycosyl transferase family group 2
IAFFMICD_00686 2e-81 S Protein conserved in bacteria
IAFFMICD_00687 8.6e-74
IAFFMICD_00688 9.3e-74 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
IAFFMICD_00689 5.3e-58 2.7.7.65 T diguanylate cyclase
IAFFMICD_00690 5.7e-162 nox C NADH oxidase
IAFFMICD_00691 3.7e-72 yliE T Putative diguanylate phosphodiesterase
IAFFMICD_00692 4.3e-26
IAFFMICD_00693 3.7e-67 K MarR family
IAFFMICD_00694 4e-11 S response to antibiotic
IAFFMICD_00695 6e-123 S Putative esterase
IAFFMICD_00696 6.4e-183
IAFFMICD_00697 3.5e-103 rmaB K Transcriptional regulator, MarR family
IAFFMICD_00698 1.3e-84 F NUDIX domain
IAFFMICD_00699 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAFFMICD_00700 3.4e-29
IAFFMICD_00701 4.4e-125 S zinc-ribbon domain
IAFFMICD_00702 2e-197 pbpX1 V Beta-lactamase
IAFFMICD_00703 1.5e-181 K AI-2E family transporter
IAFFMICD_00704 1.1e-127 srtA 3.4.22.70 M Sortase family
IAFFMICD_00705 1.5e-65 gtcA S Teichoic acid glycosylation protein
IAFFMICD_00706 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IAFFMICD_00707 7.6e-123 gbuC E glycine betaine
IAFFMICD_00708 8e-30 gbuC E glycine betaine
IAFFMICD_00709 1.8e-124 proW E glycine betaine
IAFFMICD_00710 6.5e-221 gbuA 3.6.3.32 E glycine betaine
IAFFMICD_00711 2.2e-131 sfsA S Belongs to the SfsA family
IAFFMICD_00712 1.6e-66 usp1 T Universal stress protein family
IAFFMICD_00713 1.8e-250 yxbA 6.3.1.12 S ATP-grasp enzyme
IAFFMICD_00714 3.4e-155 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IAFFMICD_00715 1.4e-281 thrC 4.2.3.1 E Threonine synthase
IAFFMICD_00716 1.3e-229 hom 1.1.1.3 E homoserine dehydrogenase
IAFFMICD_00717 6.7e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
IAFFMICD_00718 5.8e-166 yqiK S SPFH domain / Band 7 family
IAFFMICD_00719 5.7e-68
IAFFMICD_00720 1.5e-154 pfoS S Phosphotransferase system, EIIC
IAFFMICD_00721 5.9e-180 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAFFMICD_00722 4.2e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IAFFMICD_00723 6.2e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
IAFFMICD_00724 6e-143 S Alpha/beta hydrolase family
IAFFMICD_00725 2.3e-102 K Bacterial regulatory proteins, tetR family
IAFFMICD_00726 1.2e-171 XK27_06930 V domain protein
IAFFMICD_00727 2.1e-171 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAFFMICD_00728 0.0 asnB 6.3.5.4 E Asparagine synthase
IAFFMICD_00729 2.2e-08
IAFFMICD_00730 5.2e-206 S Calcineurin-like phosphoesterase
IAFFMICD_00731 1.5e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IAFFMICD_00732 7.3e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IAFFMICD_00733 1.2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAFFMICD_00734 8.8e-167 natA S ABC transporter
IAFFMICD_00735 1.6e-209 ysdA CP ABC-2 family transporter protein
IAFFMICD_00736 8.1e-64 K helix_turn_helix gluconate operon transcriptional repressor
IAFFMICD_00737 4.9e-162 CcmA V ABC transporter
IAFFMICD_00738 5.7e-115 VPA0052 I ABC-2 family transporter protein
IAFFMICD_00739 5.8e-146 IQ reductase
IAFFMICD_00740 9.3e-259 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_00741 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IAFFMICD_00742 1.7e-159 licT K CAT RNA binding domain
IAFFMICD_00743 7.2e-284 cydC V ABC transporter transmembrane region
IAFFMICD_00744 6.1e-310 cydD CO ABC transporter transmembrane region
IAFFMICD_00745 1.7e-75 ynhH S NusG domain II
IAFFMICD_00746 2.8e-170 M Peptidoglycan-binding domain 1 protein
IAFFMICD_00748 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IAFFMICD_00749 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IAFFMICD_00750 6.5e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IAFFMICD_00751 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
IAFFMICD_00752 4.1e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IAFFMICD_00753 6.5e-174 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAFFMICD_00754 1.7e-37
IAFFMICD_00755 4.9e-87
IAFFMICD_00756 2.7e-24
IAFFMICD_00757 5.2e-162 yicL EG EamA-like transporter family
IAFFMICD_00758 1.9e-112 tag 3.2.2.20 L glycosylase
IAFFMICD_00759 4.2e-77 usp5 T universal stress protein
IAFFMICD_00760 4.7e-64 K Helix-turn-helix XRE-family like proteins
IAFFMICD_00761 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
IAFFMICD_00762 1.3e-223 queG 1.17.99.6 C Domain of unknown function (DUF1730)
IAFFMICD_00763 4.1e-62
IAFFMICD_00764 1.4e-87 bioY S BioY family
IAFFMICD_00766 4.2e-102 Q methyltransferase
IAFFMICD_00767 2.6e-98 T Sh3 type 3 domain protein
IAFFMICD_00768 3.9e-113 yfeJ 6.3.5.2 F glutamine amidotransferase
IAFFMICD_00769 8e-137 S Uncharacterized protein conserved in bacteria (DUF2263)
IAFFMICD_00770 4.9e-257 yhdP S Transporter associated domain
IAFFMICD_00771 7.2e-144 S Alpha beta hydrolase
IAFFMICD_00772 3e-195 I Acyltransferase
IAFFMICD_00773 2.4e-37 lmrB EGP Major facilitator Superfamily
IAFFMICD_00774 1.7e-213 lmrB EGP Major facilitator Superfamily
IAFFMICD_00775 8.8e-84 S Domain of unknown function (DUF4811)
IAFFMICD_00776 4.2e-95 maf D nucleoside-triphosphate diphosphatase activity
IAFFMICD_00777 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAFFMICD_00778 2.8e-293 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAFFMICD_00779 4.2e-178 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAFFMICD_00780 0.0 ydaO E amino acid
IAFFMICD_00781 1.1e-56 S Domain of unknown function (DUF1827)
IAFFMICD_00782 4.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IAFFMICD_00783 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IAFFMICD_00784 7.2e-110 ydiL S CAAX protease self-immunity
IAFFMICD_00785 5.3e-51 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IAFFMICD_00786 7.5e-135 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IAFFMICD_00787 1.2e-183
IAFFMICD_00788 9.7e-158 ytrB V ABC transporter
IAFFMICD_00789 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
IAFFMICD_00790 4.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IAFFMICD_00791 0.0 uup S ABC transporter, ATP-binding protein
IAFFMICD_00792 1.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_00793 1.8e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAFFMICD_00794 2.3e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IAFFMICD_00795 5.3e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IAFFMICD_00796 7e-119
IAFFMICD_00797 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
IAFFMICD_00798 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
IAFFMICD_00799 1.3e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
IAFFMICD_00800 1.7e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IAFFMICD_00801 1.7e-57 yabA L Involved in initiation control of chromosome replication
IAFFMICD_00802 1.3e-174 holB 2.7.7.7 L DNA polymerase III
IAFFMICD_00803 7.8e-52 yaaQ S Cyclic-di-AMP receptor
IAFFMICD_00804 2.2e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAFFMICD_00805 8.7e-38 S Protein of unknown function (DUF2508)
IAFFMICD_00806 5.6e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAFFMICD_00807 1.5e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IAFFMICD_00808 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAFFMICD_00809 8.9e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IAFFMICD_00810 4.7e-49
IAFFMICD_00811 3.4e-106 rsmC 2.1.1.172 J Methyltransferase
IAFFMICD_00812 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAFFMICD_00813 4.7e-70 tnpB L Putative transposase DNA-binding domain
IAFFMICD_00814 5e-125 spl M NlpC/P60 family
IAFFMICD_00815 2e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAFFMICD_00816 2.6e-161 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAFFMICD_00817 1.4e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
IAFFMICD_00818 1.3e-173 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IAFFMICD_00819 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
IAFFMICD_00820 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IAFFMICD_00821 3.1e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
IAFFMICD_00822 7.9e-200 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
IAFFMICD_00823 1.7e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IAFFMICD_00824 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IAFFMICD_00825 4.7e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IAFFMICD_00826 1.3e-112 ylcC 3.4.22.70 M Sortase family
IAFFMICD_00827 3.4e-144 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAFFMICD_00828 0.0 fbp 3.1.3.11 G phosphatase activity
IAFFMICD_00829 1.3e-64 nrp 1.20.4.1 P ArsC family
IAFFMICD_00830 0.0 clpL O associated with various cellular activities
IAFFMICD_00831 7.6e-143 ywqE 3.1.3.48 GM PHP domain protein
IAFFMICD_00832 2.4e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IAFFMICD_00833 9.2e-76 cpsE M Bacterial sugar transferase
IAFFMICD_00834 1.5e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IAFFMICD_00835 1.3e-201 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IAFFMICD_00836 8.6e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IAFFMICD_00837 2.2e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IAFFMICD_00838 7.7e-63 wcmJ S SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
IAFFMICD_00839 1.8e-57 cps1B GT2,GT4 M Glycosyl transferases group 1
IAFFMICD_00840 6.6e-07 S EpsG family
IAFFMICD_00841 2.5e-72 rgpB GT2 M Glycosyl transferase family 2
IAFFMICD_00842 1.1e-25 rfbF GT2 V Glycosyl transferase, family 2
IAFFMICD_00843 3.3e-43 wbbK M Glycosyl transferases group 1
IAFFMICD_00844 8.9e-38 wbbL S Glycosyl transferase family 2
IAFFMICD_00845 3e-89 cps2J S Polysaccharide biosynthesis protein
IAFFMICD_00846 5.8e-111 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IAFFMICD_00847 1e-109 epsB M biosynthesis protein
IAFFMICD_00848 2.8e-131 E lipolytic protein G-D-S-L family
IAFFMICD_00849 1.1e-81 ccl S QueT transporter
IAFFMICD_00850 1.5e-124 IQ Enoyl-(Acyl carrier protein) reductase
IAFFMICD_00851 1.4e-36 XK27_01315 S Protein of unknown function (DUF2829)
IAFFMICD_00852 4.9e-48 K Cro/C1-type HTH DNA-binding domain
IAFFMICD_00853 3.3e-115 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
IAFFMICD_00854 1.5e-180 oppF P Belongs to the ABC transporter superfamily
IAFFMICD_00855 1.3e-196 oppD P Belongs to the ABC transporter superfamily
IAFFMICD_00856 1.4e-176 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAFFMICD_00857 3e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAFFMICD_00858 7.4e-305 oppA E ABC transporter, substratebinding protein
IAFFMICD_00859 1.6e-253 EGP Major facilitator Superfamily
IAFFMICD_00860 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAFFMICD_00861 6.4e-128 yrjD S LUD domain
IAFFMICD_00862 1e-289 lutB C 4Fe-4S dicluster domain
IAFFMICD_00863 4.7e-148 lutA C Cysteine-rich domain
IAFFMICD_00864 9.1e-101
IAFFMICD_00865 2.8e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IAFFMICD_00866 1.5e-211 S Bacterial protein of unknown function (DUF871)
IAFFMICD_00867 1.8e-69 S Domain of unknown function (DUF3284)
IAFFMICD_00868 4e-270 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAFFMICD_00869 0.0 rafA 3.2.1.22 G alpha-galactosidase
IAFFMICD_00870 1.4e-133 S Belongs to the UPF0246 family
IAFFMICD_00871 2e-132 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
IAFFMICD_00872 1.4e-84 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
IAFFMICD_00873 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
IAFFMICD_00874 1.3e-108
IAFFMICD_00875 2e-101 S WxL domain surface cell wall-binding
IAFFMICD_00876 1e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
IAFFMICD_00877 5.7e-286 G Phosphodiester glycosidase
IAFFMICD_00879 6.2e-274 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
IAFFMICD_00880 6.9e-206 S Protein of unknown function (DUF917)
IAFFMICD_00881 3.5e-222 F Permease for cytosine/purines, uracil, thiamine, allantoin
IAFFMICD_00882 1.3e-116
IAFFMICD_00883 2.3e-53 hsdS-1 3.1.21.3 V Type I restriction modification DNA specificity domain
IAFFMICD_00884 2e-166 L Belongs to the 'phage' integrase family
IAFFMICD_00885 3.3e-68 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IAFFMICD_00886 1.9e-215 hsdM 2.1.1.72 V type I restriction-modification system
IAFFMICD_00887 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IAFFMICD_00888 7e-212 ykiI
IAFFMICD_00889 0.0 pip V domain protein
IAFFMICD_00890 0.0 scrA 2.7.1.211 G phosphotransferase system
IAFFMICD_00891 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IAFFMICD_00892 1.5e-175 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IAFFMICD_00893 9.4e-299 scrB 3.2.1.26 GH32 G invertase
IAFFMICD_00895 7.8e-160 azoB GM NmrA-like family
IAFFMICD_00896 6.5e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IAFFMICD_00897 2e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IAFFMICD_00898 5.3e-150 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAFFMICD_00899 3.6e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IAFFMICD_00900 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IAFFMICD_00901 1.1e-43 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IAFFMICD_00902 2e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IAFFMICD_00903 2.8e-126 IQ reductase
IAFFMICD_00904 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IAFFMICD_00905 2.4e-173 fabK 1.3.1.9 S Nitronate monooxygenase
IAFFMICD_00906 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAFFMICD_00907 1.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAFFMICD_00908 2.1e-76 marR K Winged helix DNA-binding domain
IAFFMICD_00909 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IAFFMICD_00910 2.5e-152 I carboxylic ester hydrolase activity
IAFFMICD_00911 4.7e-91 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IAFFMICD_00912 1.5e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAFFMICD_00913 6.9e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IAFFMICD_00914 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IAFFMICD_00915 8.9e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IAFFMICD_00916 2.3e-182 vraS 2.7.13.3 T Histidine kinase
IAFFMICD_00917 5.8e-115 vraR K helix_turn_helix, Lux Regulon
IAFFMICD_00918 2.9e-53 yneR S Belongs to the HesB IscA family
IAFFMICD_00919 0.0 S Bacterial membrane protein YfhO
IAFFMICD_00920 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IAFFMICD_00921 9.6e-121 gluP 3.4.21.105 S Peptidase, S54 family
IAFFMICD_00922 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
IAFFMICD_00923 2e-177 glk 2.7.1.2 G Glucokinase
IAFFMICD_00924 3.7e-72 yqhL P Rhodanese-like protein
IAFFMICD_00925 9.8e-25 WQ51_02665 S Protein of unknown function (DUF3042)
IAFFMICD_00926 5.7e-180 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IAFFMICD_00927 1.6e-129 ynbB 4.4.1.1 P aluminum resistance
IAFFMICD_00928 1.2e-100 ynbB 4.4.1.1 P aluminum resistance
IAFFMICD_00929 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
IAFFMICD_00930 1e-60 glnR K Transcriptional regulator
IAFFMICD_00931 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
IAFFMICD_00932 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IAFFMICD_00933 1.1e-263 V ABC transporter transmembrane region
IAFFMICD_00935 2.5e-233 ywhK S Membrane
IAFFMICD_00936 4.1e-14
IAFFMICD_00937 3.8e-32
IAFFMICD_00938 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IAFFMICD_00939 1.2e-55 ysxB J Cysteine protease Prp
IAFFMICD_00940 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IAFFMICD_00941 7e-203 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IAFFMICD_00942 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAFFMICD_00943 1.5e-72 yqhY S Asp23 family, cell envelope-related function
IAFFMICD_00944 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAFFMICD_00945 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAFFMICD_00946 2.1e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IAFFMICD_00947 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IAFFMICD_00948 1.8e-145 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IAFFMICD_00949 5.2e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IAFFMICD_00950 2e-74 argR K Regulates arginine biosynthesis genes
IAFFMICD_00951 5.7e-308 recN L May be involved in recombinational repair of damaged DNA
IAFFMICD_00952 6e-51
IAFFMICD_00953 4.7e-120 rssA S Patatin-like phospholipase
IAFFMICD_00954 3.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IAFFMICD_00955 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IAFFMICD_00956 5.2e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAFFMICD_00957 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAFFMICD_00958 2.3e-34 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAFFMICD_00959 1.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IAFFMICD_00960 1e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAFFMICD_00961 2e-135 stp 3.1.3.16 T phosphatase
IAFFMICD_00962 0.0 KLT serine threonine protein kinase
IAFFMICD_00963 1.9e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IAFFMICD_00964 9.7e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IAFFMICD_00965 1.3e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
IAFFMICD_00966 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IAFFMICD_00967 2.3e-57 asp S Asp23 family, cell envelope-related function
IAFFMICD_00968 4.7e-286 yloV S DAK2 domain fusion protein YloV
IAFFMICD_00969 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAFFMICD_00970 1.5e-186 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IAFFMICD_00971 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAFFMICD_00972 4.4e-194 oppD P Belongs to the ABC transporter superfamily
IAFFMICD_00973 5.3e-178 oppF P Belongs to the ABC transporter superfamily
IAFFMICD_00974 2.8e-174 oppB P ABC transporter permease
IAFFMICD_00975 8.2e-136 oppC EP Binding-protein-dependent transport system inner membrane component
IAFFMICD_00976 0.0 oppA1 E ABC transporter substrate-binding protein
IAFFMICD_00977 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IAFFMICD_00978 8.3e-165 smc D Required for chromosome condensation and partitioning
IAFFMICD_00979 4.3e-19 smc D Required for chromosome condensation and partitioning
IAFFMICD_00980 1.5e-269 smc D Required for chromosome condensation and partitioning
IAFFMICD_00981 1.3e-182 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IAFFMICD_00982 8.8e-53
IAFFMICD_00983 6.8e-24
IAFFMICD_00984 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IAFFMICD_00985 3.1e-93 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAFFMICD_00986 1.1e-115 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAFFMICD_00987 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IAFFMICD_00988 8.4e-38 ylqC S Belongs to the UPF0109 family
IAFFMICD_00989 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAFFMICD_00990 3.1e-147 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IAFFMICD_00991 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IAFFMICD_00992 1.1e-25
IAFFMICD_00993 1.1e-37 ynzC S UPF0291 protein
IAFFMICD_00994 4.8e-29 yneF S UPF0154 protein
IAFFMICD_00995 0.0 mdlA V ABC transporter
IAFFMICD_00996 0.0 mdlB V ABC transporter
IAFFMICD_00997 2.6e-138 yejC S Protein of unknown function (DUF1003)
IAFFMICD_00998 5e-201 bcaP E Amino Acid
IAFFMICD_00999 2.2e-122 plsC 2.3.1.51 I Acyltransferase
IAFFMICD_01000 4.8e-134 yabB 2.1.1.223 L Methyltransferase small domain
IAFFMICD_01001 6.9e-40 yazA L GIY-YIG catalytic domain protein
IAFFMICD_01002 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
IAFFMICD_01003 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IAFFMICD_01004 8.5e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IAFFMICD_01005 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IAFFMICD_01006 4.8e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAFFMICD_01007 7.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
IAFFMICD_01008 4.1e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IAFFMICD_01009 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IAFFMICD_01010 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAFFMICD_01011 1e-84 rimP J Required for maturation of 30S ribosomal subunits
IAFFMICD_01012 1e-202 nusA K Participates in both transcription termination and antitermination
IAFFMICD_01013 1.5e-46 ylxR K Protein of unknown function (DUF448)
IAFFMICD_01014 5.4e-44 ylxQ J ribosomal protein
IAFFMICD_01015 3.7e-151 S hydrolase
IAFFMICD_01016 7.6e-45 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IAFFMICD_01017 6e-164 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IAFFMICD_01018 3.3e-75 2.7.1.191 G PTS system sorbose subfamily IIB component
IAFFMICD_01019 7.6e-125 G PTS system sorbose-specific iic component
IAFFMICD_01020 2.3e-145 G PTS system mannose/fructose/sorbose family IID component
IAFFMICD_01021 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IAFFMICD_01022 4e-61 2.7.1.191 G PTS system fructose IIA component
IAFFMICD_01023 2.3e-309 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IAFFMICD_01024 1.9e-136 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
IAFFMICD_01026 3.5e-22
IAFFMICD_01029 1.9e-150 metQ_4 P Belongs to the nlpA lipoprotein family
IAFFMICD_01030 3.5e-196 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IAFFMICD_01031 3.1e-173
IAFFMICD_01032 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
IAFFMICD_01033 9.4e-17
IAFFMICD_01034 4e-104 K Bacterial regulatory proteins, tetR family
IAFFMICD_01035 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
IAFFMICD_01036 1e-102 dhaL 2.7.1.121 S Dak2
IAFFMICD_01037 4.6e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IAFFMICD_01038 1.2e-76 ohr O OsmC-like protein
IAFFMICD_01039 5.6e-20
IAFFMICD_01040 5.9e-13
IAFFMICD_01042 5.2e-55
IAFFMICD_01043 8.3e-252 L Exonuclease
IAFFMICD_01044 6.5e-28 relB L RelB antitoxin
IAFFMICD_01045 7e-29
IAFFMICD_01046 1.2e-48 K Helix-turn-helix domain
IAFFMICD_01047 4.8e-205 yceJ EGP Major facilitator Superfamily
IAFFMICD_01048 5.2e-104 tag 3.2.2.20 L glycosylase
IAFFMICD_01049 2.5e-77 L Resolvase, N-terminal
IAFFMICD_01050 2.3e-215 tnpB L Putative transposase DNA-binding domain
IAFFMICD_01052 9.1e-33
IAFFMICD_01053 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IAFFMICD_01054 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IAFFMICD_01055 6.1e-45
IAFFMICD_01056 8.2e-153 V Beta-lactamase
IAFFMICD_01057 7.3e-192 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IAFFMICD_01058 6e-137 H Protein of unknown function (DUF1698)
IAFFMICD_01059 1.7e-140 puuD S peptidase C26
IAFFMICD_01060 3.5e-107 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
IAFFMICD_01061 1.3e-78 K Psort location Cytoplasmic, score
IAFFMICD_01062 8.1e-257 6.3.1.2 E Glutamine synthetase N-terminal domain
IAFFMICD_01063 3.6e-221 S Amidohydrolase
IAFFMICD_01064 8e-227 E Amino acid permease
IAFFMICD_01065 2.5e-74 K helix_turn_helix, mercury resistance
IAFFMICD_01066 6.4e-162 morA2 S reductase
IAFFMICD_01067 2.8e-193 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IAFFMICD_01068 4e-59 hxlR K Transcriptional regulator, HxlR family
IAFFMICD_01069 1.5e-127 S membrane transporter protein
IAFFMICD_01070 3.6e-197
IAFFMICD_01071 4.6e-129 XK27_12140 V ATPases associated with a variety of cellular activities
IAFFMICD_01072 1.7e-293 S Psort location CytoplasmicMembrane, score
IAFFMICD_01073 2e-126 K Transcriptional regulatory protein, C terminal
IAFFMICD_01074 5.1e-196 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IAFFMICD_01075 1.9e-161 V ATPases associated with a variety of cellular activities
IAFFMICD_01076 9.3e-198
IAFFMICD_01077 1.4e-105
IAFFMICD_01078 0.0 pepN 3.4.11.2 E aminopeptidase
IAFFMICD_01079 2.4e-275 ycaM E amino acid
IAFFMICD_01080 6.4e-238 G MFS/sugar transport protein
IAFFMICD_01081 6e-72 S Protein of unknown function (DUF1440)
IAFFMICD_01082 2.3e-161 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IAFFMICD_01083 1e-173 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IAFFMICD_01085 7.9e-37
IAFFMICD_01086 2.4e-89
IAFFMICD_01088 7.4e-211 metC 4.4.1.8 E cystathionine
IAFFMICD_01089 2.8e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IAFFMICD_01090 2.2e-120 tcyB E ABC transporter
IAFFMICD_01091 2.2e-117
IAFFMICD_01092 1.5e-253 brnQ U Component of the transport system for branched-chain amino acids
IAFFMICD_01093 4.1e-76 S WxL domain surface cell wall-binding
IAFFMICD_01094 1e-174 S Cell surface protein
IAFFMICD_01095 1.2e-42
IAFFMICD_01096 3.1e-247 XK27_00720 S Leucine-rich repeat (LRR) protein
IAFFMICD_01098 5e-120 S WxL domain surface cell wall-binding
IAFFMICD_01099 4.5e-56
IAFFMICD_01100 3e-114 N WxL domain surface cell wall-binding
IAFFMICD_01101 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IAFFMICD_01102 1.6e-166 yicL EG EamA-like transporter family
IAFFMICD_01103 4.4e-300
IAFFMICD_01104 8.5e-145 CcmA5 V ABC transporter
IAFFMICD_01105 6.2e-78 S ECF-type riboflavin transporter, S component
IAFFMICD_01106 7.7e-135 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IAFFMICD_01107 1.2e-09
IAFFMICD_01108 1.3e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IAFFMICD_01109 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
IAFFMICD_01110 7.8e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAFFMICD_01111 1.7e-115 ymfM S Helix-turn-helix domain
IAFFMICD_01112 1.1e-127 IQ Enoyl-(Acyl carrier protein) reductase
IAFFMICD_01113 2.2e-243 ymfH S Peptidase M16
IAFFMICD_01114 5.1e-229 ymfF S Peptidase M16 inactive domain protein
IAFFMICD_01115 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IAFFMICD_01116 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
IAFFMICD_01117 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IAFFMICD_01118 2.4e-153 rrmA 2.1.1.187 H Methyltransferase
IAFFMICD_01119 5.7e-172 corA P CorA-like Mg2+ transporter protein
IAFFMICD_01120 7.4e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IAFFMICD_01121 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAFFMICD_01122 1.2e-61 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IAFFMICD_01123 2.3e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IAFFMICD_01124 3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IAFFMICD_01125 1.3e-111 cutC P Participates in the control of copper homeostasis
IAFFMICD_01126 1.2e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IAFFMICD_01127 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IAFFMICD_01128 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAFFMICD_01129 2.7e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
IAFFMICD_01130 1.2e-103 yjbK S CYTH
IAFFMICD_01131 1.5e-115 yjbH Q Thioredoxin
IAFFMICD_01132 1.1e-211 coiA 3.6.4.12 S Competence protein
IAFFMICD_01133 1.3e-243 XK27_08635 S UPF0210 protein
IAFFMICD_01134 1.5e-37 gcvR T Belongs to the UPF0237 family
IAFFMICD_01135 2.9e-222 cpdA S Calcineurin-like phosphoesterase
IAFFMICD_01136 6.7e-226 malY 4.4.1.8 E Aminotransferase, class I
IAFFMICD_01137 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IAFFMICD_01139 2.6e-95 FNV0100 F NUDIX domain
IAFFMICD_01140 8.9e-137 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAFFMICD_01141 3.3e-35 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IAFFMICD_01142 3.4e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IAFFMICD_01143 5.4e-279 ytgP S Polysaccharide biosynthesis protein
IAFFMICD_01144 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAFFMICD_01145 6.7e-119 3.6.1.27 I Acid phosphatase homologues
IAFFMICD_01146 2.1e-113 S Domain of unknown function (DUF4811)
IAFFMICD_01147 8.1e-266 lmrB EGP Major facilitator Superfamily
IAFFMICD_01148 1.3e-81 merR K MerR HTH family regulatory protein
IAFFMICD_01149 2.1e-274 emrY EGP Major facilitator Superfamily
IAFFMICD_01150 1.7e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAFFMICD_01151 2.6e-99
IAFFMICD_01153 5.6e-201 M Glycosyl hydrolases family 25
IAFFMICD_01154 3.7e-43 hol S Bacteriophage holin
IAFFMICD_01155 6.1e-48
IAFFMICD_01156 1.4e-12
IAFFMICD_01157 0.0 S cellulase activity
IAFFMICD_01158 6.8e-241 S Phage tail protein
IAFFMICD_01159 0.0 S peptidoglycan catabolic process
IAFFMICD_01160 1.8e-21
IAFFMICD_01161 1.6e-74 S Pfam:Phage_TTP_1
IAFFMICD_01162 1.5e-30
IAFFMICD_01163 2.9e-66 S exonuclease activity
IAFFMICD_01164 1.2e-39 S Phage head-tail joining protein
IAFFMICD_01165 2.7e-26 S Phage gp6-like head-tail connector protein
IAFFMICD_01166 1e-21 S peptidase activity
IAFFMICD_01167 8.1e-208 S peptidase activity
IAFFMICD_01168 2.3e-105 S peptidase activity
IAFFMICD_01169 8.7e-229 S Phage portal protein
IAFFMICD_01171 0.0 S Phage Terminase
IAFFMICD_01172 5.7e-77 S Phage terminase, small subunit
IAFFMICD_01173 6.6e-73 S HNH endonuclease
IAFFMICD_01176 2e-34 S HNH endonuclease
IAFFMICD_01177 4.1e-231
IAFFMICD_01178 5.4e-12
IAFFMICD_01179 1.7e-19
IAFFMICD_01180 1.6e-73
IAFFMICD_01181 3.7e-32 S YopX protein
IAFFMICD_01183 7.2e-21
IAFFMICD_01185 9.8e-26
IAFFMICD_01188 8.5e-20
IAFFMICD_01189 7.7e-73 S magnesium ion binding
IAFFMICD_01190 3.9e-35
IAFFMICD_01191 1.1e-51
IAFFMICD_01193 7.7e-08 K Cro/C1-type HTH DNA-binding domain
IAFFMICD_01194 8.7e-68 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IAFFMICD_01195 1.9e-138 L Replication initiation and membrane attachment
IAFFMICD_01196 1.4e-77 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IAFFMICD_01197 4e-42 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IAFFMICD_01198 8.7e-151 recT L RecT family
IAFFMICD_01201 2.7e-08
IAFFMICD_01205 1.6e-102 S Phage regulatory protein Rha (Phage_pRha)
IAFFMICD_01206 2.1e-09 cro K Helix-turn-helix XRE-family like proteins
IAFFMICD_01207 1.6e-96 3.4.21.88 K Helix-turn-helix
IAFFMICD_01208 5.8e-19 3.4.21.88 K Peptidase S24-like
IAFFMICD_01209 8e-91 3.1.21.3 V Type I restriction modification DNA specificity domain
IAFFMICD_01211 1.7e-09
IAFFMICD_01212 3.7e-210 L Belongs to the 'phage' integrase family
IAFFMICD_01214 4.6e-139 cad S FMN_bind
IAFFMICD_01215 0.0 ndh 1.6.99.3 C NADH dehydrogenase
IAFFMICD_01216 1.7e-81 ynhH S NusG domain II
IAFFMICD_01217 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
IAFFMICD_01218 4.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IAFFMICD_01219 2.7e-80
IAFFMICD_01220 6.9e-147 T Calcineurin-like phosphoesterase superfamily domain
IAFFMICD_01221 4.6e-97
IAFFMICD_01222 2.6e-158
IAFFMICD_01223 2.7e-152 V ATPases associated with a variety of cellular activities
IAFFMICD_01224 7.1e-215
IAFFMICD_01225 2.4e-193
IAFFMICD_01226 2.5e-121 1.5.1.40 S Rossmann-like domain
IAFFMICD_01227 4.8e-102 XK27_00915 C Luciferase-like monooxygenase
IAFFMICD_01228 5.4e-75 XK27_00915 C Luciferase-like monooxygenase
IAFFMICD_01229 1.2e-97 yacP S YacP-like NYN domain
IAFFMICD_01230 7e-144 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAFFMICD_01231 2.1e-73 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IAFFMICD_01232 2.5e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAFFMICD_01233 3.3e-245 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
IAFFMICD_01234 7.3e-21
IAFFMICD_01236 3.3e-259 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAFFMICD_01237 1e-140 yhfC S Putative membrane peptidase family (DUF2324)
IAFFMICD_01238 1.8e-155 S Membrane
IAFFMICD_01239 2.8e-61 K helix_turn_helix gluconate operon transcriptional repressor
IAFFMICD_01240 2.9e-293 V ABC transporter transmembrane region
IAFFMICD_01241 4.4e-223 inlJ M MucBP domain
IAFFMICD_01242 1.9e-69 S ABC-2 family transporter protein
IAFFMICD_01243 3.1e-95 V ABC transporter, ATP-binding protein
IAFFMICD_01244 1.4e-108 K sequence-specific DNA binding
IAFFMICD_01245 6.8e-201 yacL S domain protein
IAFFMICD_01246 6.4e-197 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IAFFMICD_01247 1.9e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
IAFFMICD_01248 4.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
IAFFMICD_01249 2.7e-257 pepC 3.4.22.40 E aminopeptidase
IAFFMICD_01250 3.8e-262 pepC 3.4.22.40 E Peptidase C1-like family
IAFFMICD_01251 3.6e-194
IAFFMICD_01252 1.9e-209 S ABC-2 family transporter protein
IAFFMICD_01253 4.3e-166 V ATPases associated with a variety of cellular activities
IAFFMICD_01254 0.0 kup P Transport of potassium into the cell
IAFFMICD_01255 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
IAFFMICD_01256 1.5e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
IAFFMICD_01257 2.9e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAFFMICD_01258 4e-201 ltrA S Bacterial low temperature requirement A protein (LtrA)
IAFFMICD_01259 7.2e-46
IAFFMICD_01260 2.8e-194 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IAFFMICD_01261 8.8e-09 yhjA S CsbD-like
IAFFMICD_01262 3.1e-151 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAFFMICD_01263 9.2e-191 EGP Major facilitator Superfamily
IAFFMICD_01264 8.5e-115 udp 2.4.2.3, 3.2.2.4 F Phosphorylase superfamily
IAFFMICD_01265 7.3e-172 EGP Major facilitator Superfamily
IAFFMICD_01266 5.3e-95 KT Purine catabolism regulatory protein-like family
IAFFMICD_01267 5.4e-08
IAFFMICD_01268 2.5e-32
IAFFMICD_01269 7.4e-34
IAFFMICD_01270 4.9e-224 pimH EGP Major facilitator Superfamily
IAFFMICD_01271 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IAFFMICD_01272 3e-148 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAFFMICD_01274 8.7e-93
IAFFMICD_01275 9.8e-33 bacI V MacB-like periplasmic core domain
IAFFMICD_01276 3.1e-55 macB V ABC transporter, ATP-binding protein
IAFFMICD_01278 5.3e-134 3.4.22.70 M Sortase family
IAFFMICD_01279 3.2e-289 M Cna protein B-type domain
IAFFMICD_01280 5.1e-259 M domain protein
IAFFMICD_01281 4.1e-56 M domain protein
IAFFMICD_01282 0.0 M domain protein
IAFFMICD_01283 3.3e-103
IAFFMICD_01284 4.3e-225 N Uncharacterized conserved protein (DUF2075)
IAFFMICD_01285 1.8e-206 MA20_36090 S Protein of unknown function (DUF2974)
IAFFMICD_01286 4.1e-97 K Helix-turn-helix XRE-family like proteins
IAFFMICD_01287 1.4e-56 K Transcriptional regulator PadR-like family
IAFFMICD_01288 7.1e-136
IAFFMICD_01289 6.6e-134
IAFFMICD_01290 9e-44 S Enterocin A Immunity
IAFFMICD_01291 2.7e-186 tas C Aldo/keto reductase family
IAFFMICD_01292 7.2e-83 yqeH S Ribosome biogenesis GTPase YqeH
IAFFMICD_01293 2.4e-95 yqeG S HAD phosphatase, family IIIA
IAFFMICD_01294 2e-166 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAFFMICD_01295 1.2e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAFFMICD_01296 1.8e-121 mhqD S Dienelactone hydrolase family
IAFFMICD_01297 3.7e-179 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
IAFFMICD_01298 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
IAFFMICD_01299 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAFFMICD_01300 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IAFFMICD_01301 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAFFMICD_01302 8.8e-236 spoVK O ATPase family associated with various cellular activities (AAA)
IAFFMICD_01303 3.5e-12
IAFFMICD_01304 4.2e-37 yfjR K WYL domain
IAFFMICD_01305 6.5e-125 S SseB protein N-terminal domain
IAFFMICD_01306 5.5e-65
IAFFMICD_01307 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAFFMICD_01308 5.8e-169 dnaI L Primosomal protein DnaI
IAFFMICD_01309 2.1e-249 dnaB L replication initiation and membrane attachment
IAFFMICD_01310 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAFFMICD_01311 2.3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAFFMICD_01312 4.6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IAFFMICD_01313 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAFFMICD_01314 1.3e-117 ybhL S Inhibitor of apoptosis-promoting Bax1
IAFFMICD_01315 1.8e-187 S Cell surface protein
IAFFMICD_01317 2.1e-135 S WxL domain surface cell wall-binding
IAFFMICD_01318 0.0 N domain, Protein
IAFFMICD_01319 5.3e-265 K Mga helix-turn-helix domain
IAFFMICD_01320 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IAFFMICD_01321 2.8e-28 sftA D Belongs to the FtsK SpoIIIE SftA family
IAFFMICD_01322 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IAFFMICD_01324 1.2e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IAFFMICD_01325 7.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IAFFMICD_01327 4.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IAFFMICD_01328 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
IAFFMICD_01330 9e-223 ecsB U ABC transporter
IAFFMICD_01331 4.9e-131 ecsA V ABC transporter, ATP-binding protein
IAFFMICD_01332 5.5e-74 hit FG histidine triad
IAFFMICD_01333 7.4e-48 yhaH S YtxH-like protein
IAFFMICD_01334 2.6e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IAFFMICD_01335 2.1e-182 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
IAFFMICD_01336 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
IAFFMICD_01337 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IAFFMICD_01338 3.6e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IAFFMICD_01339 2e-74 argR K Regulates arginine biosynthesis genes
IAFFMICD_01340 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IAFFMICD_01342 5.9e-67
IAFFMICD_01343 6.1e-22
IAFFMICD_01344 1.2e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IAFFMICD_01345 4.5e-303 glpQ 3.1.4.46 C phosphodiesterase
IAFFMICD_01346 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IAFFMICD_01347 1.5e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IAFFMICD_01348 7.9e-137 yhfI S Metallo-beta-lactamase superfamily
IAFFMICD_01349 7.6e-91 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
IAFFMICD_01350 0.0 V ABC transporter (permease)
IAFFMICD_01351 2.6e-138 bceA V ABC transporter
IAFFMICD_01352 3.8e-122 K response regulator
IAFFMICD_01353 1.3e-207 T PhoQ Sensor
IAFFMICD_01354 3.2e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAFFMICD_01355 0.0 copB 3.6.3.4 P P-type ATPase
IAFFMICD_01356 1.6e-76 copR K Copper transport repressor CopY TcrY
IAFFMICD_01357 3.6e-219 purD 6.3.4.13 F Belongs to the GARS family
IAFFMICD_01358 2.9e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IAFFMICD_01359 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAFFMICD_01360 2.1e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IAFFMICD_01361 5.7e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IAFFMICD_01362 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAFFMICD_01363 3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAFFMICD_01364 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAFFMICD_01365 2.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IAFFMICD_01366 5.1e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAFFMICD_01367 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAFFMICD_01368 1.6e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
IAFFMICD_01370 1.2e-253 iolT EGP Major facilitator Superfamily
IAFFMICD_01371 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
IAFFMICD_01372 4.9e-171 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
IAFFMICD_01373 5.2e-142 cmpC S ABC transporter, ATP-binding protein
IAFFMICD_01374 7.6e-156 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
IAFFMICD_01375 1.2e-164 XK27_00670 S ABC transporter
IAFFMICD_01376 8e-166 XK27_00670 S ABC transporter substrate binding protein
IAFFMICD_01378 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
IAFFMICD_01379 5.2e-116 ywnB S NmrA-like family
IAFFMICD_01380 1.5e-06
IAFFMICD_01381 2.7e-199
IAFFMICD_01382 1.9e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IAFFMICD_01383 1.7e-88 S Short repeat of unknown function (DUF308)
IAFFMICD_01385 5.9e-121 yrkL S Flavodoxin-like fold
IAFFMICD_01386 7.4e-149 cytC6 I alpha/beta hydrolase fold
IAFFMICD_01387 7.5e-209 mutY L A G-specific adenine glycosylase
IAFFMICD_01388 3.1e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
IAFFMICD_01389 1.3e-14
IAFFMICD_01390 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IAFFMICD_01391 4.3e-211 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IAFFMICD_01392 1.9e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IAFFMICD_01393 1.9e-141 lacR K DeoR C terminal sensor domain
IAFFMICD_01394 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
IAFFMICD_01395 9.9e-94 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
IAFFMICD_01396 5.6e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
IAFFMICD_01397 3.2e-175 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
IAFFMICD_01398 1.3e-125 S Domain of unknown function (DUF4867)
IAFFMICD_01399 8e-188 V Beta-lactamase
IAFFMICD_01400 1.7e-28
IAFFMICD_01402 2.3e-249 gatC G PTS system sugar-specific permease component
IAFFMICD_01403 1.7e-48 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_01404 3.3e-70 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01406 1.4e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IAFFMICD_01407 1.5e-162 K Transcriptional regulator
IAFFMICD_01408 6.5e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IAFFMICD_01409 9.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IAFFMICD_01410 6.2e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAFFMICD_01412 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
IAFFMICD_01413 6.2e-247 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_01414 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
IAFFMICD_01415 6.5e-138 lacT K PRD domain
IAFFMICD_01416 3.3e-135 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
IAFFMICD_01417 1.1e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAFFMICD_01418 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
IAFFMICD_01419 3.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IAFFMICD_01420 2e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
IAFFMICD_01421 9.1e-274 mutS L ATPase domain of DNA mismatch repair MUTS family
IAFFMICD_01422 2.3e-311 ybiT S ABC transporter, ATP-binding protein
IAFFMICD_01423 1.2e-10
IAFFMICD_01425 9.3e-147 F DNA RNA non-specific endonuclease
IAFFMICD_01426 1.5e-118 yhiD S MgtC family
IAFFMICD_01427 4e-178 yfeX P Peroxidase
IAFFMICD_01428 2.2e-243 amt P ammonium transporter
IAFFMICD_01429 2e-158 3.5.1.10 C nadph quinone reductase
IAFFMICD_01430 1.1e-92 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
IAFFMICD_01431 1.2e-52 ybjQ S Belongs to the UPF0145 family
IAFFMICD_01432 6.9e-113 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
IAFFMICD_01433 2.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
IAFFMICD_01434 1.7e-157 cylA V ABC transporter
IAFFMICD_01435 6.4e-146 cylB V ABC-2 type transporter
IAFFMICD_01436 2.8e-68 K LytTr DNA-binding domain
IAFFMICD_01437 3.2e-55 S Protein of unknown function (DUF3021)
IAFFMICD_01438 0.0 yjcE P Sodium proton antiporter
IAFFMICD_01439 2.8e-283 S Protein of unknown function (DUF3800)
IAFFMICD_01440 7.1e-256 yifK E Amino acid permease
IAFFMICD_01441 3.7e-160 yeaE S Aldo/keto reductase family
IAFFMICD_01442 3.9e-113 ylbE GM NAD(P)H-binding
IAFFMICD_01443 8.1e-96 lsa S ABC transporter
IAFFMICD_01444 1.8e-173 lsa S ABC transporter
IAFFMICD_01445 3.5e-76 O OsmC-like protein
IAFFMICD_01446 1.3e-70
IAFFMICD_01447 1.1e-158 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
IAFFMICD_01448 4.9e-109 K Transcriptional regulator, LysR family
IAFFMICD_01449 1.2e-172 C FAD dependent oxidoreductase
IAFFMICD_01450 1.4e-238 P transporter
IAFFMICD_01451 4.9e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IAFFMICD_01452 1.2e-149 sorM G system, mannose fructose sorbose family IID component
IAFFMICD_01453 3.6e-130 sorA U PTS system sorbose-specific iic component
IAFFMICD_01454 1.9e-78 sorB 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
IAFFMICD_01455 3.6e-62 sorF 2.7.1.191, 2.7.1.206 G PTS system fructose IIA component
IAFFMICD_01456 4.1e-131 IQ NAD dependent epimerase/dehydratase family
IAFFMICD_01457 2.2e-163 sorC K sugar-binding domain protein
IAFFMICD_01458 5.4e-239 sorE E Alcohol dehydrogenase GroES-like domain
IAFFMICD_01459 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphotransferase system
IAFFMICD_01460 6.4e-154 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IAFFMICD_01461 3e-286 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01462 2e-156 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
IAFFMICD_01463 2.5e-125 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IAFFMICD_01464 1.4e-91 IQ KR domain
IAFFMICD_01465 1.1e-180 2.7.1.53 G Belongs to the FGGY kinase family
IAFFMICD_01466 9.9e-39 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IAFFMICD_01467 1.1e-88 4.1.2.13 G DeoC/LacD family aldolase
IAFFMICD_01468 6.3e-118 K helix_turn_helix gluconate operon transcriptional repressor
IAFFMICD_01469 1.4e-44 K Acetyltransferase (GNAT) family
IAFFMICD_01470 1.3e-212 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
IAFFMICD_01471 2.1e-155 rihB 3.2.2.1 F Nucleoside
IAFFMICD_01472 3.8e-87 6.3.4.4 S Zeta toxin
IAFFMICD_01473 3.2e-150 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IAFFMICD_01474 1.2e-41
IAFFMICD_01475 1.4e-205 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IAFFMICD_01476 6e-46 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_01477 6.7e-165 GKT transcriptional antiterminator
IAFFMICD_01478 1e-28
IAFFMICD_01479 3.9e-104
IAFFMICD_01480 2.3e-67 K helix_turn_helix multiple antibiotic resistance protein
IAFFMICD_01481 3.6e-141 ydiC1 EGP Major facilitator Superfamily
IAFFMICD_01482 1.3e-77 ydiC1 EGP Major facilitator Superfamily
IAFFMICD_01483 2.3e-94
IAFFMICD_01484 4.5e-62
IAFFMICD_01485 1.3e-80
IAFFMICD_01486 7.1e-86 V AAA domain, putative AbiEii toxin, Type IV TA system
IAFFMICD_01487 5.5e-52
IAFFMICD_01488 8.5e-280 pbpC M NTF2-like N-terminal transpeptidase domain
IAFFMICD_01489 3.6e-58 pbpC M NTF2-like N-terminal transpeptidase domain
IAFFMICD_01490 3.1e-142 S Protein of unknown function (DUF2785)
IAFFMICD_01495 2.5e-36
IAFFMICD_01496 1.8e-42 K DNA-binding helix-turn-helix protein
IAFFMICD_01497 6.2e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAFFMICD_01498 4.3e-159 rbsB G Periplasmic binding protein domain
IAFFMICD_01499 1e-152 rbsC U Belongs to the binding-protein-dependent transport system permease family
IAFFMICD_01500 1.3e-269 rbsA 3.6.3.17 G ABC transporter
IAFFMICD_01501 8.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IAFFMICD_01502 9.7e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
IAFFMICD_01503 3.3e-272 E Amino acid permease
IAFFMICD_01504 3.2e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IAFFMICD_01505 1.6e-101 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IAFFMICD_01506 6e-58 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IAFFMICD_01507 9.3e-78 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IAFFMICD_01508 1.1e-81 thiW S Thiamine-precursor transporter protein (ThiW)
IAFFMICD_01509 1.7e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAFFMICD_01510 1.6e-109 P cobalt transport
IAFFMICD_01511 1.3e-243 P ABC transporter
IAFFMICD_01512 5.7e-95 S ABC-type cobalt transport system, permease component
IAFFMICD_01513 1.3e-27
IAFFMICD_01514 5.8e-33
IAFFMICD_01515 3.8e-277 nisT V ABC transporter
IAFFMICD_01516 1.3e-119 S Acetyltransferase (GNAT) family
IAFFMICD_01517 3.2e-292 E ABC transporter, substratebinding protein
IAFFMICD_01518 3.6e-235 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IAFFMICD_01519 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01520 5.8e-194 ypdE E M42 glutamyl aminopeptidase
IAFFMICD_01521 1.9e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IAFFMICD_01522 1.8e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_01523 2.7e-252 2.7.1.207 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAFFMICD_01524 5.1e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IAFFMICD_01525 1.6e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IAFFMICD_01526 1.2e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAFFMICD_01528 1.2e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IAFFMICD_01529 3e-273 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IAFFMICD_01531 1.1e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAFFMICD_01532 4.7e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IAFFMICD_01533 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAFFMICD_01534 3.9e-125 atpB C it plays a direct role in the translocation of protons across the membrane
IAFFMICD_01535 1.3e-111 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAFFMICD_01536 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAFFMICD_01537 4.4e-61 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IAFFMICD_01538 1.4e-116 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IAFFMICD_01539 2.6e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IAFFMICD_01540 4.8e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAFFMICD_01541 6e-111 tdk 2.7.1.21 F thymidine kinase
IAFFMICD_01542 1.9e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IAFFMICD_01543 2.2e-190 ampC V Beta-lactamase
IAFFMICD_01544 2.3e-164 1.13.11.2 S glyoxalase
IAFFMICD_01545 7.8e-140 S NADPH-dependent FMN reductase
IAFFMICD_01546 0.0 yfiC V ABC transporter
IAFFMICD_01547 0.0 ycfI V ABC transporter, ATP-binding protein
IAFFMICD_01548 5.4e-121 K Bacterial regulatory proteins, tetR family
IAFFMICD_01549 1e-131 G Phosphoglycerate mutase family
IAFFMICD_01550 8.7e-09
IAFFMICD_01554 2.2e-284 pipD E Dipeptidase
IAFFMICD_01555 2.5e-193 yttB EGP Major facilitator Superfamily
IAFFMICD_01556 1.2e-17
IAFFMICD_01564 5.8e-85 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
IAFFMICD_01565 1.4e-172 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IAFFMICD_01566 3.3e-230 wbbX GT2,GT4 M Glycosyl transferases group 1
IAFFMICD_01567 5.6e-74 yttA 2.7.13.3 S Pfam Transposase IS66
IAFFMICD_01568 2e-115 F DNA/RNA non-specific endonuclease
IAFFMICD_01569 5.6e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
IAFFMICD_01571 7.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
IAFFMICD_01572 2.9e-151 glcU U sugar transport
IAFFMICD_01573 1.5e-109 vanZ V VanZ like family
IAFFMICD_01574 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IAFFMICD_01575 4.7e-129
IAFFMICD_01576 1.2e-103
IAFFMICD_01578 1.4e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAFFMICD_01579 3e-204 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAFFMICD_01580 7.3e-242 pbuX F xanthine permease
IAFFMICD_01581 7.9e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IAFFMICD_01582 1.3e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
IAFFMICD_01583 1.4e-81 yvbK 3.1.3.25 K GNAT family
IAFFMICD_01584 2.4e-26 chpR T PFAM SpoVT AbrB
IAFFMICD_01585 2.1e-31 cspC K Cold shock protein
IAFFMICD_01586 3.3e-167 yqjA S Putative aromatic acid exporter C-terminal domain
IAFFMICD_01587 2.1e-109
IAFFMICD_01588 2.1e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IAFFMICD_01589 1.6e-83 S Fic/DOC family
IAFFMICD_01590 3e-304 S Psort location CytoplasmicMembrane, score
IAFFMICD_01591 0.0 S Bacterial membrane protein YfhO
IAFFMICD_01592 1.8e-307 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IAFFMICD_01593 4.5e-233 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_01594 9.1e-36 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_01595 6.2e-220 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IAFFMICD_01596 2.1e-39 M transferase activity, transferring glycosyl groups
IAFFMICD_01597 4.7e-56 M Glycosyl transferase family 8
IAFFMICD_01598 4.1e-119 M lipopolysaccharide 3-alpha-galactosyltransferase activity
IAFFMICD_01599 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IAFFMICD_01600 2.6e-197 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IAFFMICD_01601 4.5e-29
IAFFMICD_01603 1.3e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IAFFMICD_01604 1.1e-184 hrtB V ABC transporter permease
IAFFMICD_01605 9.6e-86 ygfC K Bacterial regulatory proteins, tetR family
IAFFMICD_01606 4.8e-145 yqfZ 3.2.1.17 M hydrolase, family 25
IAFFMICD_01607 1.3e-17 S YvrJ protein family
IAFFMICD_01608 8.7e-08 K DNA-templated transcription, initiation
IAFFMICD_01609 2.5e-119
IAFFMICD_01610 6.7e-58 pnb C nitroreductase
IAFFMICD_01611 2.4e-18 hxlR K Transcriptional regulator, HxlR family
IAFFMICD_01612 9.6e-199 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01613 5.8e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
IAFFMICD_01614 7e-87 4.3.3.7 E Dihydrodipicolinate synthetase family
IAFFMICD_01615 4.3e-183 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IAFFMICD_01616 3e-31 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_01617 7.5e-45 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01618 2.4e-62 kdsD 5.3.1.13 M SIS domain
IAFFMICD_01619 1.1e-218 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01620 2.2e-189 malY 4.4.1.8 E Aminotransferase class I and II
IAFFMICD_01621 9e-268 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_01622 7.2e-61 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01623 1.2e-28 glvR K DNA-binding transcription factor activity
IAFFMICD_01624 7.8e-175 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IAFFMICD_01625 2.5e-85 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
IAFFMICD_01626 9.6e-188 2.7.1.199, 2.7.1.208 G pts system
IAFFMICD_01627 6.4e-199 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IAFFMICD_01628 3.8e-109 5.3.1.15 S Pfam:DUF1498
IAFFMICD_01629 6.3e-126 G Domain of unknown function (DUF4432)
IAFFMICD_01630 1.2e-162 G Phosphotransferase System
IAFFMICD_01631 5.7e-44 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_01632 8e-66 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01633 1.9e-167 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IAFFMICD_01634 3.1e-30 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IAFFMICD_01635 1.1e-230 manR K PRD domain
IAFFMICD_01636 2e-232 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_01637 1.2e-234 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IAFFMICD_01638 7.5e-91 K antiterminator
IAFFMICD_01639 9.4e-52 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IAFFMICD_01640 3e-44 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IAFFMICD_01641 2.8e-20 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
IAFFMICD_01643 3.2e-38 glvR K Helix-turn-helix domain, rpiR family
IAFFMICD_01644 1.6e-210 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
IAFFMICD_01645 6.6e-219 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
IAFFMICD_01646 9.3e-67 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
IAFFMICD_01647 2.2e-132 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
IAFFMICD_01648 1.9e-25 2.7.1.194 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAFFMICD_01649 3.1e-168 S PTS system sugar-specific permease component
IAFFMICD_01650 3.3e-37 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01651 1.1e-57 gntR K rpiR family
IAFFMICD_01652 1.3e-54 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IAFFMICD_01653 5.9e-63 K DeoR C terminal sensor domain
IAFFMICD_01654 4.1e-30 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01655 8.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_01656 4.8e-188 pts36C G iic component
IAFFMICD_01657 3.9e-97 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
IAFFMICD_01658 2.2e-250 frdC 1.3.5.4 C HI0933-like protein
IAFFMICD_01659 3e-235 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IAFFMICD_01660 2.7e-47 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IAFFMICD_01661 4.7e-244 G Major Facilitator
IAFFMICD_01662 1e-150 K Transcriptional regulator, LacI family
IAFFMICD_01663 1.8e-145 cbiQ P cobalt transport
IAFFMICD_01664 0.0 3.6.3.24 P ATP-binding cassette cobalt transporter
IAFFMICD_01665 2.7e-97 S UPF0397 protein
IAFFMICD_01666 8.5e-60
IAFFMICD_01667 6.7e-287
IAFFMICD_01669 1.6e-34 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
IAFFMICD_01670 1.7e-254 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
IAFFMICD_01672 9.9e-299 2.4.1.52 GT4 M Glycosyl transferases group 1
IAFFMICD_01673 7.7e-278 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IAFFMICD_01674 1.9e-186 mocA S Oxidoreductase
IAFFMICD_01675 3.8e-91 K Bacterial regulatory proteins, tetR family
IAFFMICD_01676 9.2e-112 1.6.5.2 S Flavodoxin-like fold
IAFFMICD_01678 3.2e-61
IAFFMICD_01679 2.3e-26
IAFFMICD_01680 3.1e-60 S Protein of unknown function (DUF1093)
IAFFMICD_01681 3.1e-37
IAFFMICD_01682 3.2e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IAFFMICD_01683 2e-83 XK27_03960 S Protein of unknown function (DUF3013)
IAFFMICD_01684 3e-173 prmA J Ribosomal protein L11 methyltransferase
IAFFMICD_01685 5.7e-101 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IAFFMICD_01686 4e-53
IAFFMICD_01687 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAFFMICD_01688 5.2e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IAFFMICD_01689 7.2e-115 3.1.3.18 J HAD-hyrolase-like
IAFFMICD_01690 5.2e-248 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
IAFFMICD_01691 1e-78 FG adenosine 5'-monophosphoramidase activity
IAFFMICD_01692 5.6e-158 V ABC transporter
IAFFMICD_01693 1.3e-266
IAFFMICD_01694 1.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
IAFFMICD_01695 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IAFFMICD_01696 1.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IAFFMICD_01697 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAFFMICD_01698 4.7e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IAFFMICD_01699 7.2e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IAFFMICD_01700 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IAFFMICD_01701 1.6e-68 yqeY S YqeY-like protein
IAFFMICD_01702 2.9e-179 phoH T phosphate starvation-inducible protein PhoH
IAFFMICD_01703 1.4e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IAFFMICD_01704 1.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IAFFMICD_01705 1.4e-10 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IAFFMICD_01706 1.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAFFMICD_01707 5.8e-15 recO L Involved in DNA repair and RecF pathway recombination
IAFFMICD_01708 4.6e-111 recO L Involved in DNA repair and RecF pathway recombination
IAFFMICD_01709 3.9e-53
IAFFMICD_01710 1e-120 V ATPases associated with a variety of cellular activities
IAFFMICD_01712 2e-94 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
IAFFMICD_01713 1.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IAFFMICD_01714 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IAFFMICD_01715 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IAFFMICD_01716 4.1e-31 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IAFFMICD_01717 3.2e-150 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IAFFMICD_01718 1.7e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
IAFFMICD_01719 1.8e-147 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAFFMICD_01720 2.8e-310 V ABC transporter transmembrane region
IAFFMICD_01721 2.2e-271 V (ABC) transporter
IAFFMICD_01722 3.6e-188 cggR K Putative sugar-binding domain
IAFFMICD_01724 2.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IAFFMICD_01725 2.4e-69 ohrR K helix_turn_helix multiple antibiotic resistance protein
IAFFMICD_01726 1.6e-171 whiA K May be required for sporulation
IAFFMICD_01727 1.7e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IAFFMICD_01728 1.3e-165 rapZ S Displays ATPase and GTPase activities
IAFFMICD_01729 6.7e-85 S Short repeat of unknown function (DUF308)
IAFFMICD_01730 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IAFFMICD_01731 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IAFFMICD_01732 5.5e-118 yfbR S HD containing hydrolase-like enzyme
IAFFMICD_01733 6.1e-149 V FtsX-like permease family
IAFFMICD_01734 1.1e-52 V FtsX-like permease family
IAFFMICD_01735 1.2e-91 V ABC transporter
IAFFMICD_01736 8.9e-115 T His Kinase A (phosphoacceptor) domain
IAFFMICD_01737 6.8e-84 T Transcriptional regulatory protein, C terminal
IAFFMICD_01738 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IAFFMICD_01739 3.2e-83 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IAFFMICD_01740 1.7e-59 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IAFFMICD_01741 3.4e-194 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IAFFMICD_01742 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IAFFMICD_01743 2.8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IAFFMICD_01744 1.3e-46 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IAFFMICD_01745 7.1e-32
IAFFMICD_01746 4.8e-210 yvlB S Putative adhesin
IAFFMICD_01747 1e-119 phoU P Plays a role in the regulation of phosphate uptake
IAFFMICD_01748 7.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IAFFMICD_01749 1.2e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IAFFMICD_01750 1.1e-156 pstA P Phosphate transport system permease protein PstA
IAFFMICD_01751 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
IAFFMICD_01752 2e-135 pstS P Phosphate
IAFFMICD_01753 1.1e-306 phoR 2.7.13.3 T Histidine kinase
IAFFMICD_01754 5.2e-130 K response regulator
IAFFMICD_01755 3.2e-195 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
IAFFMICD_01756 1.8e-159 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IAFFMICD_01757 1.9e-124 ftsE D ABC transporter
IAFFMICD_01758 8.9e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IAFFMICD_01759 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IAFFMICD_01760 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAFFMICD_01761 1.3e-90 comFC S Competence protein
IAFFMICD_01762 8.2e-235 comFA L Helicase C-terminal domain protein
IAFFMICD_01763 9.5e-118 yvyE 3.4.13.9 S YigZ family
IAFFMICD_01764 1.7e-242 rny S Endoribonuclease that initiates mRNA decay
IAFFMICD_01765 1.6e-10
IAFFMICD_01766 2.8e-67 K Acetyltransferase (GNAT) domain
IAFFMICD_01767 9.3e-112 gmk2 2.7.4.8 F Guanylate kinase
IAFFMICD_01768 1.8e-08
IAFFMICD_01769 5.6e-85 zur P Belongs to the Fur family
IAFFMICD_01771 1.3e-171
IAFFMICD_01772 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAFFMICD_01774 6.5e-148 glnH ET ABC transporter substrate-binding protein
IAFFMICD_01775 7.9e-109 gluC P ABC transporter permease
IAFFMICD_01776 1.1e-110 glnP P ABC transporter permease
IAFFMICD_01777 9.2e-175 cps2D 5.1.3.2 M RmlD substrate binding domain
IAFFMICD_01778 2.1e-113 tuaG GT2 M Glycosyltransferase like family 2
IAFFMICD_01779 1.4e-133 M Glycosyltransferase sugar-binding region containing DXD motif
IAFFMICD_01780 1.5e-253 wcaJ M Bacterial sugar transferase
IAFFMICD_01781 1.6e-85
IAFFMICD_01782 1.9e-198 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IAFFMICD_01783 5.8e-159 ykoT GT2 M Glycosyl transferase family 2
IAFFMICD_01784 1.9e-112 icaC M Acyltransferase family
IAFFMICD_01785 5.8e-179 M Dolichyl-phosphate-mannose-protein mannosyltransferase
IAFFMICD_01786 2.4e-300 M Glycosyl hydrolases family 25
IAFFMICD_01787 1.3e-222 S Bacterial membrane protein, YfhO
IAFFMICD_01788 1.8e-120 tagF 2.7.8.12 M Glycosyltransferase like family 2
IAFFMICD_01789 3.8e-199 M Glycosyl transferases group 1
IAFFMICD_01790 1.6e-247 S polysaccharide biosynthetic process
IAFFMICD_01791 1.6e-99 ywqC M capsule polysaccharide biosynthetic process
IAFFMICD_01792 7.4e-83 epsG 2.7.10.1 D Capsular exopolysaccharide family
IAFFMICD_01793 4.7e-156 S EpsG family
IAFFMICD_01794 0.0 M Sulfatase
IAFFMICD_01795 5.7e-111 nodB3 G Polysaccharide deacetylase
IAFFMICD_01796 6.9e-237 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAFFMICD_01797 4.1e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
IAFFMICD_01798 0.0 E amino acid
IAFFMICD_01799 1.2e-135 cysA V ABC transporter, ATP-binding protein
IAFFMICD_01800 0.0 V FtsX-like permease family
IAFFMICD_01801 5e-170 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IAFFMICD_01802 1.2e-128 pgm3 G Phosphoglycerate mutase family
IAFFMICD_01803 5.6e-183 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IAFFMICD_01804 2.4e-216 mntH P H( )-stimulated, divalent metal cation uptake system
IAFFMICD_01805 2.9e-81 yjhE S Phage tail protein
IAFFMICD_01806 9.2e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IAFFMICD_01807 0.0 yjbQ P TrkA C-terminal domain protein
IAFFMICD_01808 2.3e-27
IAFFMICD_01809 2.9e-43 trxC O Belongs to the thioredoxin family
IAFFMICD_01810 2.8e-132 thrE S Putative threonine/serine exporter
IAFFMICD_01811 3.5e-74 S Threonine/Serine exporter, ThrE
IAFFMICD_01812 1.3e-213 livJ E Receptor family ligand binding region
IAFFMICD_01813 6.7e-151 livH U Branched-chain amino acid transport system / permease component
IAFFMICD_01814 1.7e-120 livM E Branched-chain amino acid transport system / permease component
IAFFMICD_01815 4.7e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
IAFFMICD_01816 1.8e-122 livF E ABC transporter
IAFFMICD_01817 1.2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
IAFFMICD_01818 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
IAFFMICD_01819 2.3e-232 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAFFMICD_01820 1.9e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IAFFMICD_01821 4.4e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAFFMICD_01822 2.2e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IAFFMICD_01823 2.1e-144 p75 M NlpC P60 family protein
IAFFMICD_01824 3.3e-225 nox 1.6.3.4 C NADH oxidase
IAFFMICD_01825 2e-258 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
IAFFMICD_01826 7.8e-144 K CAT RNA binding domain
IAFFMICD_01827 5.2e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
IAFFMICD_01828 1.2e-234 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_01829 4.8e-154 sepS16B
IAFFMICD_01830 1.1e-116
IAFFMICD_01831 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
IAFFMICD_01832 6.2e-238 malE G Bacterial extracellular solute-binding protein
IAFFMICD_01833 1.7e-82
IAFFMICD_01834 2.2e-295 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01835 3.1e-67 frvA 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_01836 5.7e-240 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
IAFFMICD_01837 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
IAFFMICD_01838 3.4e-129 XK27_08435 K UTRA
IAFFMICD_01839 5.9e-219 agaS G SIS domain
IAFFMICD_01840 4.1e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAFFMICD_01841 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
IAFFMICD_01842 8.1e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
IAFFMICD_01843 2.2e-141 XK27_08455 G PTS system sorbose-specific iic component
IAFFMICD_01844 1e-145 manZ_1 G PTS system mannose/fructose/sorbose family IID component
IAFFMICD_01845 3.5e-64 XK27_08465 2.7.1.191 G PTS system fructose IIA component
IAFFMICD_01846 1.5e-294 2.4.1.52 GT4 M Glycosyl transferases group 1
IAFFMICD_01847 2.2e-311 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IAFFMICD_01848 4.9e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
IAFFMICD_01849 2.3e-170 4.4.1.8 E Aminotransferase, class I
IAFFMICD_01850 6.4e-32 ywzB S Protein of unknown function (DUF1146)
IAFFMICD_01851 4.5e-180 mbl D Cell shape determining protein MreB Mrl
IAFFMICD_01852 1.9e-25 epuA S DNA-directed RNA polymerase subunit beta
IAFFMICD_01853 1.6e-54 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IAFFMICD_01854 1.3e-31 S Protein of unknown function (DUF2969)
IAFFMICD_01855 7.6e-222 rodA D Belongs to the SEDS family
IAFFMICD_01856 1.1e-47 gcvH E glycine cleavage
IAFFMICD_01857 3.2e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IAFFMICD_01858 1.9e-147 P Belongs to the nlpA lipoprotein family
IAFFMICD_01859 3.8e-148 P Belongs to the nlpA lipoprotein family
IAFFMICD_01860 2.9e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAFFMICD_01861 8.8e-106 metI P ABC transporter permease
IAFFMICD_01862 1.9e-141 sufC O FeS assembly ATPase SufC
IAFFMICD_01863 5.9e-191 sufD O FeS assembly protein SufD
IAFFMICD_01864 5.8e-222 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAFFMICD_01865 2.9e-78 nifU C SUF system FeS assembly protein, NifU family
IAFFMICD_01866 1.2e-279 sufB O assembly protein SufB
IAFFMICD_01868 1.8e-26
IAFFMICD_01869 1.1e-65 yueI S Protein of unknown function (DUF1694)
IAFFMICD_01870 2e-180 S Protein of unknown function (DUF2785)
IAFFMICD_01871 4.4e-158 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IAFFMICD_01872 1.5e-83 usp6 T universal stress protein
IAFFMICD_01873 1.7e-39
IAFFMICD_01874 3.3e-237 rarA L recombination factor protein RarA
IAFFMICD_01875 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
IAFFMICD_01876 1e-72 yueI S Protein of unknown function (DUF1694)
IAFFMICD_01877 4.1e-107 yktB S Belongs to the UPF0637 family
IAFFMICD_01878 2.2e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IAFFMICD_01879 7.3e-150 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IAFFMICD_01880 3e-122 G Phosphoglycerate mutase family
IAFFMICD_01881 7.3e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAFFMICD_01882 1.7e-165 IQ NAD dependent epimerase/dehydratase family
IAFFMICD_01883 2.7e-137 pnuC H nicotinamide mononucleotide transporter
IAFFMICD_01884 2.6e-132 dck 2.7.1.74 F deoxynucleoside kinase
IAFFMICD_01885 1.7e-156 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IAFFMICD_01886 0.0 oppA E ABC transporter, substratebinding protein
IAFFMICD_01887 1.8e-151 T GHKL domain
IAFFMICD_01888 4e-119 T Transcriptional regulatory protein, C terminal
IAFFMICD_01889 1.9e-167 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
IAFFMICD_01890 8.2e-129 S ABC-2 family transporter protein
IAFFMICD_01891 9.4e-161 K Transcriptional regulator
IAFFMICD_01892 7.2e-79 yphH S Cupin domain
IAFFMICD_01893 4.2e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
IAFFMICD_01895 2.2e-11 K Psort location Cytoplasmic, score
IAFFMICD_01896 2e-83 K Psort location Cytoplasmic, score
IAFFMICD_01897 1.5e-163 2.3.1.128 K Acetyltransferase (GNAT) domain
IAFFMICD_01898 1.7e-84 K Acetyltransferase (GNAT) domain
IAFFMICD_01899 1.4e-153 S Uncharacterised protein, DegV family COG1307
IAFFMICD_01900 3.7e-106
IAFFMICD_01901 4.2e-37 desR K helix_turn_helix, Lux Regulon
IAFFMICD_01902 0.0 helD 3.6.4.12 L DNA helicase
IAFFMICD_01903 1.2e-82 ykhA 3.1.2.20 I Thioesterase superfamily
IAFFMICD_01904 1.2e-274 pipD E Dipeptidase
IAFFMICD_01905 2.4e-41
IAFFMICD_01906 4.4e-53
IAFFMICD_01907 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IAFFMICD_01908 2.1e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IAFFMICD_01909 1.5e-44 S Abortive infection C-terminus
IAFFMICD_01911 7.4e-79 K Putative DNA-binding domain
IAFFMICD_01912 4.6e-56
IAFFMICD_01913 1.8e-13 M LysM domain
IAFFMICD_01918 1.3e-24 K Cro/C1-type HTH DNA-binding domain
IAFFMICD_01920 5.8e-37 L Plasmid pRiA4b ORF-3-like protein
IAFFMICD_01921 5.9e-94 L restriction endonuclease
IAFFMICD_01922 2.3e-48 lciIC K Helix-turn-helix XRE-family like proteins
IAFFMICD_01924 4.6e-163 lytN 3.5.1.104 M LysM domain
IAFFMICD_01925 8e-258 lytN 3.5.1.104 M LysM domain
IAFFMICD_01927 2.7e-23 WQ51_00220 K Helix-turn-helix XRE-family like proteins
IAFFMICD_01928 1.5e-114 zmp3 O Zinc-dependent metalloprotease
IAFFMICD_01929 9e-137 2.7.1.39 S Phosphotransferase enzyme family
IAFFMICD_01930 9.3e-68 S Iron-sulphur cluster biosynthesis
IAFFMICD_01931 5.6e-281 V ABC transporter transmembrane region
IAFFMICD_01932 6.4e-288 V ABC transporter transmembrane region
IAFFMICD_01933 2.4e-35
IAFFMICD_01934 2.1e-299 E Bacterial extracellular solute-binding proteins, family 5 Middle
IAFFMICD_01935 1e-168 oppB P Binding-protein-dependent transport system inner membrane component
IAFFMICD_01936 3e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
IAFFMICD_01937 1.7e-48
IAFFMICD_01938 2.2e-196 oppD P Oligopeptide/dipeptide transporter, C-terminal region
IAFFMICD_01939 1.3e-162 oppF P Oligopeptide/dipeptide transporter, C-terminal region
IAFFMICD_01940 4.9e-88 V ATPases associated with a variety of cellular activities
IAFFMICD_01941 2.4e-155
IAFFMICD_01942 1.8e-16
IAFFMICD_01943 7.9e-70 skfE V ATPases associated with a variety of cellular activities
IAFFMICD_01944 1.8e-198 desK 2.7.13.3 T Histidine kinase
IAFFMICD_01945 1.6e-129 yvfS V ABC-2 type transporter
IAFFMICD_01946 4.4e-158 yvfR V ABC transporter
IAFFMICD_01947 2.5e-275
IAFFMICD_01948 9.9e-150
IAFFMICD_01949 2.2e-82 K Acetyltransferase (GNAT) domain
IAFFMICD_01950 0.0 yhgF K Tex-like protein N-terminal domain protein
IAFFMICD_01951 3.8e-139 puuD S peptidase C26
IAFFMICD_01952 5e-227 steT E Amino acid permease
IAFFMICD_01953 1.1e-133 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
IAFFMICD_01954 4.9e-100 S Domain of unknown function (DUF1998)
IAFFMICD_01955 7e-34 S Domain of unknown function (DUF1998)
IAFFMICD_01956 1e-274 KL Helicase conserved C-terminal domain
IAFFMICD_01958 2.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAFFMICD_01959 1.5e-83 ytsP 1.8.4.14 T GAF domain-containing protein
IAFFMICD_01960 1.2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IAFFMICD_01961 2.7e-216 iscS2 2.8.1.7 E Aminotransferase class V
IAFFMICD_01962 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAFFMICD_01963 1.5e-115 rex K CoA binding domain
IAFFMICD_01964 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IAFFMICD_01965 9.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IAFFMICD_01966 1.3e-114 S Haloacid dehalogenase-like hydrolase
IAFFMICD_01967 2.7e-118 radC L DNA repair protein
IAFFMICD_01968 7.8e-180 mreB D cell shape determining protein MreB
IAFFMICD_01969 8.5e-151 mreC M Involved in formation and maintenance of cell shape
IAFFMICD_01970 4.7e-83 mreD M rod shape-determining protein MreD
IAFFMICD_01971 2e-112 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IAFFMICD_01972 1.1e-141 minD D Belongs to the ParA family
IAFFMICD_01973 4.7e-109 artQ P ABC transporter permease
IAFFMICD_01974 1.7e-111 glnQ 3.6.3.21 E ABC transporter
IAFFMICD_01975 4.3e-152 aatB ET ABC transporter substrate-binding protein
IAFFMICD_01977 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IAFFMICD_01978 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IAFFMICD_01979 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
IAFFMICD_01980 8.7e-50
IAFFMICD_01981 9.7e-17
IAFFMICD_01982 6.6e-237 YSH1 S Metallo-beta-lactamase superfamily
IAFFMICD_01983 4.4e-239 malE G Bacterial extracellular solute-binding protein
IAFFMICD_01984 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
IAFFMICD_01985 2.6e-166 malG P ABC-type sugar transport systems, permease components
IAFFMICD_01986 1.6e-194 malK P ATPases associated with a variety of cellular activities
IAFFMICD_01987 4.4e-103 3.2.2.20 K Acetyltransferase (GNAT) domain
IAFFMICD_01988 9e-92 yxjI
IAFFMICD_01989 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
IAFFMICD_01990 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAFFMICD_01991 8.4e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IAFFMICD_01992 4.6e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IAFFMICD_01993 5.4e-164 natA S ABC transporter, ATP-binding protein
IAFFMICD_01994 4.8e-219 ysdA CP ABC-2 family transporter protein
IAFFMICD_01995 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
IAFFMICD_01996 1.9e-149 xth 3.1.11.2 L exodeoxyribonuclease III
IAFFMICD_01997 2.6e-166 murB 1.3.1.98 M Cell wall formation
IAFFMICD_01998 0.0 yjcE P Sodium proton antiporter
IAFFMICD_01999 2.9e-96 puuR K Cupin domain
IAFFMICD_02000 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IAFFMICD_02001 1.7e-148 potB P ABC transporter permease
IAFFMICD_02002 8.9e-145 potC P ABC transporter permease
IAFFMICD_02003 1.6e-207 potD P ABC transporter
IAFFMICD_02004 1.1e-80 S Domain of unknown function (DUF5067)
IAFFMICD_02005 1.1e-59
IAFFMICD_02007 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
IAFFMICD_02008 2.2e-117 K Transcriptional regulator
IAFFMICD_02009 1.2e-176 V ABC transporter
IAFFMICD_02010 8.1e-126 V AAA domain, putative AbiEii toxin, Type IV TA system
IAFFMICD_02011 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAFFMICD_02012 1.5e-168 ybbR S YbbR-like protein
IAFFMICD_02013 9.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAFFMICD_02014 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IAFFMICD_02016 3.3e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IAFFMICD_02017 8.6e-15
IAFFMICD_02018 0.0 V ABC transporter
IAFFMICD_02019 0.0 V ATPases associated with a variety of cellular activities
IAFFMICD_02020 8e-208 EGP Transmembrane secretion effector
IAFFMICD_02021 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IAFFMICD_02022 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAFFMICD_02023 4.8e-103 K Bacterial regulatory proteins, tetR family
IAFFMICD_02024 9.4e-184 yxeA V FtsX-like permease family
IAFFMICD_02025 1.3e-125 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
IAFFMICD_02026 6.4e-34
IAFFMICD_02027 2e-135 tipA K TipAS antibiotic-recognition domain
IAFFMICD_02028 4.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IAFFMICD_02029 1.6e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAFFMICD_02030 3.5e-157 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAFFMICD_02031 1.8e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAFFMICD_02032 9e-116
IAFFMICD_02033 3.1e-60 rplQ J Ribosomal protein L17
IAFFMICD_02034 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAFFMICD_02035 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IAFFMICD_02036 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAFFMICD_02037 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IAFFMICD_02038 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAFFMICD_02039 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IAFFMICD_02040 9.8e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IAFFMICD_02041 2.2e-62 rplO J Binds to the 23S rRNA
IAFFMICD_02042 1.7e-24 rpmD J Ribosomal protein L30
IAFFMICD_02043 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAFFMICD_02044 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IAFFMICD_02045 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAFFMICD_02046 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAFFMICD_02047 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IAFFMICD_02048 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IAFFMICD_02049 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IAFFMICD_02050 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IAFFMICD_02051 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
IAFFMICD_02052 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IAFFMICD_02053 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IAFFMICD_02054 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IAFFMICD_02055 3.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IAFFMICD_02056 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IAFFMICD_02057 5.9e-109 rplD J Forms part of the polypeptide exit tunnel
IAFFMICD_02058 3e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAFFMICD_02059 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IAFFMICD_02060 1.2e-68 psiE S Phosphate-starvation-inducible E
IAFFMICD_02061 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
IAFFMICD_02062 5.5e-197 yfjR K WYL domain
IAFFMICD_02063 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAFFMICD_02064 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IAFFMICD_02065 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAFFMICD_02066 8.6e-204 M domain protein
IAFFMICD_02067 2.9e-16
IAFFMICD_02068 2.2e-14 ytgB S Transglycosylase associated protein
IAFFMICD_02069 5.8e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IAFFMICD_02071 1.7e-69 S SdpI/YhfL protein family
IAFFMICD_02072 3.1e-133 K response regulator
IAFFMICD_02073 3.1e-268 yclK 2.7.13.3 T Histidine kinase
IAFFMICD_02074 1.3e-93 yhbS S acetyltransferase
IAFFMICD_02075 7.6e-31
IAFFMICD_02076 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
IAFFMICD_02077 3.8e-82
IAFFMICD_02078 5.3e-59
IAFFMICD_02079 3.8e-251 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
IAFFMICD_02081 6.6e-186 S response to antibiotic
IAFFMICD_02082 6.2e-108 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
IAFFMICD_02083 3.6e-46 yjgN S Bacterial protein of unknown function (DUF898)
IAFFMICD_02084 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IAFFMICD_02085 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAFFMICD_02086 6.8e-204 camS S sex pheromone
IAFFMICD_02087 4.9e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAFFMICD_02088 8.8e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IAFFMICD_02089 4e-278 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAFFMICD_02090 2.9e-193 yegS 2.7.1.107 G Lipid kinase
IAFFMICD_02091 5.7e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAFFMICD_02092 4.7e-216 yttB EGP Major facilitator Superfamily
IAFFMICD_02093 3.5e-146 cof S Sucrose-6F-phosphate phosphohydrolase
IAFFMICD_02094 1.2e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
IAFFMICD_02095 0.0 pepO 3.4.24.71 O Peptidase family M13
IAFFMICD_02096 6e-79 K Acetyltransferase (GNAT) domain
IAFFMICD_02097 4e-164 degV S Uncharacterised protein, DegV family COG1307
IAFFMICD_02098 5e-120 qmcA O prohibitin homologues
IAFFMICD_02099 3.2e-29
IAFFMICD_02100 4e-133 lys M Glycosyl hydrolases family 25
IAFFMICD_02101 1.1e-59 S Protein of unknown function (DUF1093)
IAFFMICD_02102 2e-61 S Domain of unknown function (DUF4828)
IAFFMICD_02103 2.6e-177 mocA S Oxidoreductase
IAFFMICD_02104 1.7e-235 yfmL 3.6.4.13 L DEAD DEAH box helicase
IAFFMICD_02105 6.8e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IAFFMICD_02106 7.1e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IAFFMICD_02107 4.5e-216 yqiG C Oxidoreductase
IAFFMICD_02108 1.3e-16 S Short C-terminal domain
IAFFMICD_02109 9.5e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IAFFMICD_02110 2.1e-133
IAFFMICD_02111 2e-17
IAFFMICD_02112 5.3e-279 mntH P H( )-stimulated, divalent metal cation uptake system
IAFFMICD_02113 0.0 pacL P P-type ATPase
IAFFMICD_02114 9.8e-64
IAFFMICD_02115 1.6e-239 EGP Major Facilitator Superfamily
IAFFMICD_02116 2.1e-311 mco Q Multicopper oxidase
IAFFMICD_02117 1e-24
IAFFMICD_02118 1.7e-111 2.5.1.105 P Cation efflux family
IAFFMICD_02119 8.7e-51 czrA K Transcriptional regulator, ArsR family
IAFFMICD_02120 5.4e-175 sitA P Belongs to the bacterial solute-binding protein 9 family
IAFFMICD_02121 9.5e-145 mtsB U ABC 3 transport family
IAFFMICD_02122 1.9e-130 mntB 3.6.3.35 P ABC transporter
IAFFMICD_02123 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAFFMICD_02124 7.7e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
IAFFMICD_02125 1.4e-118 GM NmrA-like family
IAFFMICD_02126 4.9e-85
IAFFMICD_02127 1.3e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
IAFFMICD_02128 1.8e-19
IAFFMICD_02130 3.4e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAFFMICD_02131 1.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAFFMICD_02132 1.4e-286 G MFS/sugar transport protein
IAFFMICD_02133 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
IAFFMICD_02134 1.6e-169 ssuA P NMT1-like family
IAFFMICD_02135 1.4e-292 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
IAFFMICD_02136 3.4e-233 yfiQ I Acyltransferase family
IAFFMICD_02137 1.3e-120 ssuB P ATPases associated with a variety of cellular activities
IAFFMICD_02138 6e-146 ssuC U Binding-protein-dependent transport system inner membrane component
IAFFMICD_02139 3.8e-122 S B3/4 domain
IAFFMICD_02140 3.6e-131 S Aldo keto reductase
IAFFMICD_02141 9.3e-155 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IAFFMICD_02142 1.7e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IAFFMICD_02143 1e-238 dinF V MatE
IAFFMICD_02144 1.2e-109 S TPM domain
IAFFMICD_02145 3.1e-102 lemA S LemA family
IAFFMICD_02146 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAFFMICD_02147 1.2e-73 EGP Major Facilitator Superfamily
IAFFMICD_02148 2.3e-251 gshR 1.8.1.7 C Glutathione reductase
IAFFMICD_02149 1.7e-176 proV E ABC transporter, ATP-binding protein
IAFFMICD_02150 8.9e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IAFFMICD_02151 0.0 helD 3.6.4.12 L DNA helicase
IAFFMICD_02152 8.8e-139 rlrG K Transcriptional regulator
IAFFMICD_02153 1.1e-175 shetA P Voltage-dependent anion channel
IAFFMICD_02154 1.5e-135 nodJ V ABC-2 type transporter
IAFFMICD_02155 3.2e-133 nodI V ABC transporter
IAFFMICD_02156 4.4e-129 ydfF K Transcriptional
IAFFMICD_02157 1.2e-109 S CAAX protease self-immunity
IAFFMICD_02159 1.7e-277 V ABC transporter transmembrane region
IAFFMICD_02160 6.7e-108 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IAFFMICD_02161 7.2e-71 K MarR family
IAFFMICD_02162 0.0 uvrA3 L excinuclease ABC
IAFFMICD_02163 1.4e-192 yghZ C Aldo keto reductase family protein
IAFFMICD_02164 8.9e-142 S hydrolase
IAFFMICD_02165 1.2e-58
IAFFMICD_02166 4.8e-12
IAFFMICD_02167 3.6e-115 yoaK S Protein of unknown function (DUF1275)
IAFFMICD_02168 2.4e-127 yjhF G Phosphoglycerate mutase family
IAFFMICD_02169 8.1e-151 yitU 3.1.3.104 S hydrolase
IAFFMICD_02170 3.6e-90 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAFFMICD_02171 5.8e-166 K LysR substrate binding domain
IAFFMICD_02172 1.3e-226 EK Aminotransferase, class I
IAFFMICD_02173 2.1e-45 ligA 6.5.1.2 L BRCA1 C Terminus (BRCT) domain
IAFFMICD_02174 2.6e-115 L Resolvase, N terminal domain
IAFFMICD_02176 5.6e-177 L Transposase and inactivated derivatives, IS30 family
IAFFMICD_02177 8.8e-305 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
IAFFMICD_02178 9.8e-09
IAFFMICD_02179 5.6e-34 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IAFFMICD_02181 6.5e-84 D CobQ CobB MinD ParA nucleotide binding domain protein
IAFFMICD_02182 2.6e-85 repA S Replication initiator protein A
IAFFMICD_02184 4.9e-21 M Cna B domain protein
IAFFMICD_02189 2.5e-220 3.1.1.32, 3.1.1.4 S COG0790 FOG TPR repeat, SEL1 subfamily
IAFFMICD_02191 0.0 L Protein of unknown function (DUF3991)
IAFFMICD_02192 4.1e-33
IAFFMICD_02193 1.1e-15
IAFFMICD_02194 8.1e-68
IAFFMICD_02196 8.8e-75
IAFFMICD_02197 6e-78 L COG3547 Transposase and inactivated derivatives
IAFFMICD_02199 6.3e-117 srtA 3.4.22.70 M Sortase family
IAFFMICD_02202 1.5e-269 L Transposase DDE domain
IAFFMICD_02203 7.2e-105 2.7.1.197, 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
IAFFMICD_02204 9.4e-29 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IAFFMICD_02205 3e-32 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IAFFMICD_02206 7e-137 2.7.1.195 G PTS mannose transporter subunit IIAB
IAFFMICD_02207 8.7e-207 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolase
IAFFMICD_02208 1.1e-68 glcU G Sugar transport protein
IAFFMICD_02210 1.5e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IAFFMICD_02211 6.9e-210 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
IAFFMICD_02212 2.2e-210 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
IAFFMICD_02213 2e-46
IAFFMICD_02214 6.3e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IAFFMICD_02215 1.8e-101 V Restriction endonuclease
IAFFMICD_02216 1.8e-158 5.1.3.3 G Aldose 1-epimerase
IAFFMICD_02217 4.4e-211 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IAFFMICD_02218 4.4e-101 S ECF transporter, substrate-specific component
IAFFMICD_02220 6.6e-81 yodP 2.3.1.264 K FR47-like protein
IAFFMICD_02221 1.3e-81 ydcK S Belongs to the SprT family
IAFFMICD_02222 2.8e-129 XK27_08845 S ABC transporter, ATP-binding protein
IAFFMICD_02223 5.6e-129 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IAFFMICD_02224 4e-176 XK27_08835 S ABC transporter
IAFFMICD_02225 6.2e-73
IAFFMICD_02226 0.0 pacL 3.6.3.8 P P-type ATPase
IAFFMICD_02227 4.6e-216 V Beta-lactamase
IAFFMICD_02228 3.7e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IAFFMICD_02229 1.3e-221 V Beta-lactamase
IAFFMICD_02230 6.1e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAFFMICD_02231 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
IAFFMICD_02232 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAFFMICD_02233 1.3e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAFFMICD_02234 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
IAFFMICD_02235 3.7e-90 sprD D Domain of Unknown Function (DUF1542)
IAFFMICD_02236 1.2e-86 S QueT transporter
IAFFMICD_02237 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
IAFFMICD_02238 1.1e-278 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IAFFMICD_02239 1.8e-130 yciB M ErfK YbiS YcfS YnhG
IAFFMICD_02240 5.1e-119 S (CBS) domain
IAFFMICD_02241 3.4e-114 1.6.5.2 S Flavodoxin-like fold
IAFFMICD_02242 1.1e-238 XK27_06930 S ABC-2 family transporter protein
IAFFMICD_02243 2.9e-96 padR K Transcriptional regulator PadR-like family
IAFFMICD_02244 5.9e-263 S Putative peptidoglycan binding domain
IAFFMICD_02245 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IAFFMICD_02246 3.1e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IAFFMICD_02247 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAFFMICD_02248 1.6e-280 yabM S Polysaccharide biosynthesis protein
IAFFMICD_02249 1.8e-38 yabO J S4 domain protein
IAFFMICD_02250 4.4e-65 divIC D cell cycle
IAFFMICD_02251 5.2e-81 yabR J RNA binding
IAFFMICD_02252 2.1e-241 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IAFFMICD_02253 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IAFFMICD_02254 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAFFMICD_02255 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IAFFMICD_02256 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAFFMICD_02257 5.6e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IAFFMICD_02258 2.9e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAFFMICD_02259 2.4e-300 frvR K Mga helix-turn-helix domain
IAFFMICD_02260 2.4e-297 frvR K Mga helix-turn-helix domain
IAFFMICD_02261 1.6e-266 lysP E amino acid
IAFFMICD_02263 5.3e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
IAFFMICD_02264 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IAFFMICD_02265 1.6e-97
IAFFMICD_02266 1.6e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
IAFFMICD_02267 1.2e-07
IAFFMICD_02268 9.5e-189 S Bacterial protein of unknown function (DUF916)
IAFFMICD_02269 8.4e-102
IAFFMICD_02270 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IAFFMICD_02271 2.3e-159 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IAFFMICD_02272 1.7e-156 I alpha/beta hydrolase fold
IAFFMICD_02273 1.3e-47
IAFFMICD_02274 6.5e-69
IAFFMICD_02275 7.9e-46
IAFFMICD_02276 1e-156 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IAFFMICD_02277 7.2e-124 citR K FCD
IAFFMICD_02278 7.2e-220 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
IAFFMICD_02279 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IAFFMICD_02280 9.8e-283 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IAFFMICD_02281 2.6e-155 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IAFFMICD_02282 2.2e-48 citD C Covalent carrier of the coenzyme of citrate lyase
IAFFMICD_02283 2.6e-103 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IAFFMICD_02285 5.3e-23 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
IAFFMICD_02286 1.5e-110 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
IAFFMICD_02287 8.7e-29 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
IAFFMICD_02288 8.7e-37 gcdC 2.3.1.12 I Biotin-requiring enzyme
IAFFMICD_02289 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAFFMICD_02290 5.2e-240 ytoI K DRTGG domain
IAFFMICD_02291 4.8e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IAFFMICD_02292 5.6e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IAFFMICD_02293 1.4e-170
IAFFMICD_02295 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAFFMICD_02296 2.3e-201
IAFFMICD_02297 4e-43 yrzL S Belongs to the UPF0297 family
IAFFMICD_02298 2.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAFFMICD_02299 2.3e-53 yrzB S Belongs to the UPF0473 family
IAFFMICD_02300 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IAFFMICD_02301 1e-67 cvpA S Colicin V production protein
IAFFMICD_02302 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IAFFMICD_02303 6.6e-53 trxA O Belongs to the thioredoxin family
IAFFMICD_02304 9.4e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAFFMICD_02305 1.8e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
IAFFMICD_02306 4e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAFFMICD_02307 1.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IAFFMICD_02308 1.1e-83 yslB S Protein of unknown function (DUF2507)
IAFFMICD_02309 2.6e-277 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IAFFMICD_02310 2.4e-95 S Phosphoesterase
IAFFMICD_02311 8.9e-133 gla U Major intrinsic protein
IAFFMICD_02312 3.3e-83 ykuL S CBS domain
IAFFMICD_02313 4.2e-156 XK27_00890 S Domain of unknown function (DUF368)
IAFFMICD_02314 1.2e-155 ykuT M mechanosensitive ion channel
IAFFMICD_02315 8.9e-289 2.4.1.52 GT4 M Glycosyl transferases group 1
IAFFMICD_02316 3.3e-302 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IAFFMICD_02317 1.7e-142 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IAFFMICD_02318 5.6e-88 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IAFFMICD_02319 2.7e-94 yqaB S Acetyltransferase (GNAT) domain
IAFFMICD_02320 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IAFFMICD_02321 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IAFFMICD_02322 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IAFFMICD_02323 2.1e-266 nylA 3.5.1.4 J Belongs to the amidase family
IAFFMICD_02324 2.4e-90 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
IAFFMICD_02325 6.1e-86 S ECF transporter, substrate-specific component
IAFFMICD_02326 3.1e-63 S Domain of unknown function (DUF4430)
IAFFMICD_02327 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
IAFFMICD_02328 5.9e-79 F nucleoside 2-deoxyribosyltransferase
IAFFMICD_02329 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
IAFFMICD_02330 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
IAFFMICD_02331 1.5e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IAFFMICD_02332 8.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IAFFMICD_02333 3.2e-170 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IAFFMICD_02334 1.1e-164 menA 2.5.1.74 M UbiA prenyltransferase family
IAFFMICD_02336 5.4e-195 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IAFFMICD_02337 3.9e-276 mga K Mga helix-turn-helix domain
IAFFMICD_02339 1.6e-157 yjjH S Calcineurin-like phosphoesterase
IAFFMICD_02340 2.6e-256 dtpT U amino acid peptide transporter
IAFFMICD_02341 0.0 macB_3 V ABC transporter, ATP-binding protein
IAFFMICD_02342 1.4e-65
IAFFMICD_02343 2.1e-73 S function, without similarity to other proteins
IAFFMICD_02344 9.9e-261 G MFS/sugar transport protein
IAFFMICD_02345 1e-231 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
IAFFMICD_02346 1e-56
IAFFMICD_02347 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
IAFFMICD_02348 2.7e-24 S Virus attachment protein p12 family
IAFFMICD_02349 2.3e-248 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IAFFMICD_02350 4.3e-141 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IAFFMICD_02351 5.2e-99 feoA P FeoA
IAFFMICD_02352 1.4e-117 E lipolytic protein G-D-S-L family
IAFFMICD_02353 3.5e-88 E AAA domain
IAFFMICD_02356 2.9e-119 ywnB S NAD(P)H-binding
IAFFMICD_02357 1.1e-91 S MucBP domain
IAFFMICD_02358 1.3e-85
IAFFMICD_02360 4.9e-74 ytxH S YtxH-like protein
IAFFMICD_02361 1.9e-92 niaR S 3H domain
IAFFMICD_02362 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IAFFMICD_02363 2.3e-179 ccpA K catabolite control protein A
IAFFMICD_02364 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
IAFFMICD_02365 1.9e-07
IAFFMICD_02366 1.3e-125 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
IAFFMICD_02367 2.6e-135 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IAFFMICD_02368 4.2e-272 pepV 3.5.1.18 E dipeptidase PepV
IAFFMICD_02369 6.8e-256 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IAFFMICD_02370 2.1e-54
IAFFMICD_02371 6.4e-188 yibE S overlaps another CDS with the same product name
IAFFMICD_02372 5.9e-116 yibF S overlaps another CDS with the same product name
IAFFMICD_02373 1.8e-115 S Calcineurin-like phosphoesterase
IAFFMICD_02374 2.2e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IAFFMICD_02375 8.8e-110 yutD S Protein of unknown function (DUF1027)
IAFFMICD_02376 1.7e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IAFFMICD_02377 5.6e-115 S Protein of unknown function (DUF1461)
IAFFMICD_02378 2.3e-116 dedA S SNARE-like domain protein
IAFFMICD_02379 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IAFFMICD_02380 7.9e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IAFFMICD_02381 3.8e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAFFMICD_02382 4.3e-64 yugI 5.3.1.9 J general stress protein
IAFFMICD_02383 1.1e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAFFMICD_02384 3.9e-116 sirR K Helix-turn-helix diphteria tox regulatory element
IAFFMICD_02385 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IAFFMICD_02386 3.9e-48 yajC U Preprotein translocase
IAFFMICD_02387 3.9e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IAFFMICD_02388 9.5e-208 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IAFFMICD_02389 6.2e-196 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IAFFMICD_02390 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IAFFMICD_02391 4.6e-103 yjbF S SNARE associated Golgi protein
IAFFMICD_02392 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IAFFMICD_02393 6.7e-220 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IAFFMICD_02394 2.9e-73 S Protein of unknown function (DUF3290)
IAFFMICD_02395 2.3e-116 yviA S Protein of unknown function (DUF421)
IAFFMICD_02396 3.4e-160 S Alpha beta hydrolase
IAFFMICD_02397 1.1e-120
IAFFMICD_02398 1.5e-157 dkgB S reductase
IAFFMICD_02399 1.3e-84 nrdI F Belongs to the NrdI family
IAFFMICD_02400 3.6e-179 D Alpha beta
IAFFMICD_02401 1.5e-77 K Transcriptional regulator
IAFFMICD_02402 1.6e-120 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
IAFFMICD_02403 3.6e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IAFFMICD_02404 4.5e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAFFMICD_02405 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IAFFMICD_02406 8.6e-218 ndh 1.6.99.3 C NADH dehydrogenase
IAFFMICD_02409 7.9e-152 S Protein of unknown function (DUF1211)
IAFFMICD_02410 5.9e-62 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IAFFMICD_02411 3.5e-79 ywiB S Domain of unknown function (DUF1934)
IAFFMICD_02412 4.6e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IAFFMICD_02413 7.4e-266 ywfO S HD domain protein
IAFFMICD_02414 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
IAFFMICD_02415 5.9e-178 S DUF218 domain
IAFFMICD_02416 1.8e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IAFFMICD_02417 1.6e-73
IAFFMICD_02418 8.6e-51 nudA S ASCH
IAFFMICD_02419 3.9e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAFFMICD_02420 2.8e-212 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IAFFMICD_02421 3.5e-219 ysaA V RDD family
IAFFMICD_02422 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IAFFMICD_02423 6.5e-119 ybbL S ABC transporter, ATP-binding protein
IAFFMICD_02424 3.3e-122 ybbM S Uncharacterised protein family (UPF0014)
IAFFMICD_02425 2.5e-158 czcD P cation diffusion facilitator family transporter
IAFFMICD_02426 5.8e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IAFFMICD_02427 1.1e-37 veg S Biofilm formation stimulator VEG
IAFFMICD_02428 0.0 pepF2 E Oligopeptidase F
IAFFMICD_02429 3.3e-91 S VanZ like family
IAFFMICD_02430 3.4e-132 yebC K Transcriptional regulatory protein
IAFFMICD_02431 7.5e-164 comGB NU type II secretion system
IAFFMICD_02432 5.1e-48
IAFFMICD_02434 1.1e-47
IAFFMICD_02435 1.1e-80
IAFFMICD_02436 4.6e-49
IAFFMICD_02437 1.7e-182 ytxK 2.1.1.72 L N-6 DNA Methylase
IAFFMICD_02438 1.3e-73
IAFFMICD_02439 1.2e-247 cycA E Amino acid permease
IAFFMICD_02440 5.8e-143 arbV 2.3.1.51 I Phosphate acyltransferases
IAFFMICD_02441 2.1e-162 arbx M Glycosyl transferase family 8
IAFFMICD_02442 2.2e-179 arbY M family 8
IAFFMICD_02443 2.9e-162 arbZ I Phosphate acyltransferases
IAFFMICD_02444 0.0 rafA 3.2.1.22 G alpha-galactosidase
IAFFMICD_02445 3.3e-214 sip L Belongs to the 'phage' integrase family
IAFFMICD_02446 2.3e-07 K Cro/C1-type HTH DNA-binding domain
IAFFMICD_02447 1.1e-43
IAFFMICD_02448 3.2e-60
IAFFMICD_02449 4.6e-14
IAFFMICD_02451 2.2e-156 L Bifunctional DNA primase/polymerase, N-terminal
IAFFMICD_02452 1.5e-145 pstS P Phosphate
IAFFMICD_02453 8.2e-37 cspA K Cold shock protein
IAFFMICD_02454 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAFFMICD_02455 1.1e-80 divIVA D DivIVA protein
IAFFMICD_02456 8.4e-145 ylmH S S4 domain protein
IAFFMICD_02457 5.2e-44 yggT D integral membrane protein
IAFFMICD_02458 6.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IAFFMICD_02459 5.4e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAFFMICD_02460 6.9e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IAFFMICD_02461 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IAFFMICD_02462 9.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAFFMICD_02463 1.3e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAFFMICD_02464 9.2e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAFFMICD_02465 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IAFFMICD_02466 6.2e-58 ftsL D cell division protein FtsL
IAFFMICD_02467 1.8e-145 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IAFFMICD_02468 4.8e-78 mraZ K Belongs to the MraZ family
IAFFMICD_02469 8.6e-09 S Protein of unknown function (DUF4044)
IAFFMICD_02470 3.1e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAFFMICD_02471 5.2e-164 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
IAFFMICD_02472 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAFFMICD_02473 3.1e-75 XK27_09600 V ABC transporter, ATP-binding protein
IAFFMICD_02474 1.1e-226 XK27_09600 V ABC transporter, ATP-binding protein
IAFFMICD_02475 0.0 V ABC transporter
IAFFMICD_02476 4.7e-219 oxlT P Major Facilitator Superfamily
IAFFMICD_02477 3.2e-127 treR K UTRA
IAFFMICD_02478 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IAFFMICD_02479 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IAFFMICD_02480 6.9e-213 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IAFFMICD_02481 1.2e-269 yfnA E Amino Acid
IAFFMICD_02482 4.3e-172 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
IAFFMICD_02483 3.3e-250 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IAFFMICD_02484 4.6e-31 K 'Cold-shock' DNA-binding domain
IAFFMICD_02485 8.5e-139 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
IAFFMICD_02486 4.7e-293 S ABC transporter
IAFFMICD_02487 1.6e-174 draG O ADP-ribosylglycohydrolase
IAFFMICD_02488 2e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IAFFMICD_02489 6.4e-52
IAFFMICD_02490 1.8e-133 XK27_06755 S Protein of unknown function (DUF975)
IAFFMICD_02491 7.5e-146 M Glycosyltransferase like family 2
IAFFMICD_02492 2.2e-134 glcR K DeoR C terminal sensor domain
IAFFMICD_02493 4.5e-70 T Sh3 type 3 domain protein
IAFFMICD_02494 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
IAFFMICD_02495 2e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IAFFMICD_02496 0.0 pepF E oligoendopeptidase F
IAFFMICD_02497 1e-159 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IAFFMICD_02498 6.4e-167 T Calcineurin-like phosphoesterase superfamily domain
IAFFMICD_02499 3e-134 znuB U ABC 3 transport family
IAFFMICD_02500 4.1e-130 fhuC 3.6.3.35 P ABC transporter
IAFFMICD_02501 4.9e-57
IAFFMICD_02502 5e-206 gntP EG Gluconate
IAFFMICD_02503 6.1e-38 M domain protein
IAFFMICD_02504 2.6e-83 3.4.23.43
IAFFMICD_02505 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAFFMICD_02506 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAFFMICD_02507 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IAFFMICD_02508 3.6e-79 ctsR K Belongs to the CtsR family
IAFFMICD_02515 5.1e-289 pepO 3.4.24.71 O Peptidase family M13
IAFFMICD_02516 1e-63 pepO 3.4.24.71 O Peptidase family M13
IAFFMICD_02517 1.6e-193 lplA 6.3.1.20 H Lipoate-protein ligase
IAFFMICD_02518 1.9e-33
IAFFMICD_02519 7.8e-174 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IAFFMICD_02520 3.7e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IAFFMICD_02522 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IAFFMICD_02523 1.9e-106 ypsA S Belongs to the UPF0398 family
IAFFMICD_02524 1.5e-120 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IAFFMICD_02525 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IAFFMICD_02526 1.2e-85 comEB 3.5.4.12 F ComE operon protein 2
IAFFMICD_02527 2.4e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAFFMICD_02528 2.4e-110 dnaD L DnaD domain protein
IAFFMICD_02529 1.2e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IAFFMICD_02530 2.4e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IAFFMICD_02531 2.1e-85 ypmB S Protein conserved in bacteria
IAFFMICD_02532 1.4e-303 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IAFFMICD_02533 2.5e-253 yjjP S Putative threonine/serine exporter
IAFFMICD_02534 7e-59
IAFFMICD_02535 1.3e-124 mesE M Transport protein ComB
IAFFMICD_02536 4.7e-83 mesE M Transport protein ComB
IAFFMICD_02537 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IAFFMICD_02539 1.2e-67 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IAFFMICD_02540 1.2e-124 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IAFFMICD_02541 7.3e-133 plnD K LytTr DNA-binding domain
IAFFMICD_02542 1.9e-44 spiA S Enterocin A Immunity
IAFFMICD_02543 5.8e-21
IAFFMICD_02547 4.4e-133 S CAAX protease self-immunity
IAFFMICD_02548 9.3e-69 K Transcriptional regulator
IAFFMICD_02549 6.4e-252 EGP Major Facilitator Superfamily
IAFFMICD_02550 2.4e-53
IAFFMICD_02551 1.9e-53 S Enterocin A Immunity
IAFFMICD_02552 1.7e-179 S Aldo keto reductase
IAFFMICD_02554 4.2e-06 mutR K Helix-turn-helix
IAFFMICD_02556 1.4e-181 K sequence-specific DNA binding
IAFFMICD_02557 3.1e-56 K Transcriptional regulator PadR-like family
IAFFMICD_02558 4e-42 ygbF S Sugar efflux transporter for intercellular exchange
IAFFMICD_02559 2.5e-49
IAFFMICD_02560 1.1e-184 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IAFFMICD_02561 3.4e-56
IAFFMICD_02562 3.4e-80
IAFFMICD_02563 2.3e-207 yubA S AI-2E family transporter
IAFFMICD_02564 7.4e-26
IAFFMICD_02565 3e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAFFMICD_02566 1.4e-75
IAFFMICD_02567 2.9e-168 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IAFFMICD_02568 1.5e-104 ywrF S Flavin reductase like domain
IAFFMICD_02569 6.7e-96
IAFFMICD_02570 1.4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAFFMICD_02571 3.3e-61 yeaO S Protein of unknown function, DUF488
IAFFMICD_02572 6.6e-173 corA P CorA-like Mg2+ transporter protein
IAFFMICD_02573 2.1e-160 mleR K LysR family
IAFFMICD_02574 1.1e-78 F Nucleoside 2-deoxyribosyltransferase
IAFFMICD_02575 4e-251 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAFFMICD_02576 6e-64
IAFFMICD_02577 2.6e-291 frvR K Mga helix-turn-helix domain
IAFFMICD_02578 4e-128 recX 2.4.1.337 GT4 S Regulatory protein RecX
IAFFMICD_02579 4e-104 ygaC J Belongs to the UPF0374 family
IAFFMICD_02580 2.8e-96
IAFFMICD_02581 8.6e-75 S Acetyltransferase (GNAT) domain
IAFFMICD_02582 6.8e-207 yueF S AI-2E family transporter
IAFFMICD_02583 4e-243 hlyX S Transporter associated domain
IAFFMICD_02584 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAFFMICD_02585 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
IAFFMICD_02586 0.0 clpE O Belongs to the ClpA ClpB family
IAFFMICD_02587 2e-28
IAFFMICD_02588 2.7e-39 ptsH G phosphocarrier protein HPR
IAFFMICD_02589 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAFFMICD_02590 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAFFMICD_02591 6.9e-68 yodB K Transcriptional regulator, HxlR family
IAFFMICD_02592 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IAFFMICD_02593 1.1e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAFFMICD_02594 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IAFFMICD_02595 4.5e-180 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IAFFMICD_02596 5.2e-287 arlS 2.7.13.3 T Histidine kinase
IAFFMICD_02597 7.9e-123 K response regulator
IAFFMICD_02598 7.2e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAFFMICD_02599 1.6e-94 yceD S Uncharacterized ACR, COG1399
IAFFMICD_02600 5.5e-206 ylbM S Belongs to the UPF0348 family
IAFFMICD_02601 1.7e-139 yqeM Q Methyltransferase
IAFFMICD_02602 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IAFFMICD_02603 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IAFFMICD_02604 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IAFFMICD_02605 1.2e-46 yhbY J RNA-binding protein
IAFFMICD_02606 8.4e-75 yqeH S Ribosome biogenesis GTPase YqeH
IAFFMICD_02607 7.3e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IAFFMICD_02608 2.8e-60 yitW S Iron-sulfur cluster assembly protein
IAFFMICD_02609 2e-140
IAFFMICD_02610 4.7e-174
IAFFMICD_02611 1.3e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IAFFMICD_02612 1.4e-195 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IAFFMICD_02613 9.6e-159 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IAFFMICD_02614 4.6e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IAFFMICD_02615 1.3e-266 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IAFFMICD_02616 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IAFFMICD_02617 2e-42 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IAFFMICD_02618 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IAFFMICD_02619 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
IAFFMICD_02620 1.7e-159 S Alpha beta hydrolase
IAFFMICD_02621 8.3e-185 K Helix-turn-helix domain
IAFFMICD_02622 4.1e-15 S membrane transporter protein
IAFFMICD_02623 2.6e-98 S membrane transporter protein
IAFFMICD_02624 6.5e-257 ypiB EGP Major facilitator Superfamily
IAFFMICD_02625 8.9e-113 K Transcriptional regulator
IAFFMICD_02626 6.1e-283 M Exporter of polyketide antibiotics
IAFFMICD_02627 3.7e-70 yjjC V ABC transporter
IAFFMICD_02628 3.8e-73 yjjC V ABC transporter
IAFFMICD_02629 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IAFFMICD_02630 4.6e-64 ORF00048
IAFFMICD_02631 1.8e-56 K Transcriptional regulator PadR-like family
IAFFMICD_02632 3.9e-105 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IAFFMICD_02633 2.5e-86 K Acetyltransferase (GNAT) domain
IAFFMICD_02634 2.4e-95 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IAFFMICD_02635 1.3e-41
IAFFMICD_02636 2.2e-241 citM C Citrate transporter
IAFFMICD_02637 7.2e-155 L Bifunctional DNA primase/polymerase, N-terminal
IAFFMICD_02638 3.3e-23
IAFFMICD_02639 2.5e-27
IAFFMICD_02640 1e-24
IAFFMICD_02641 3.8e-16
IAFFMICD_02642 2.9e-61
IAFFMICD_02646 8.3e-109 sip L Belongs to the 'phage' integrase family
IAFFMICD_02647 6.4e-07 Z012_04635 K Helix-turn-helix domain
IAFFMICD_02650 2.9e-204 lctO C IMP dehydrogenase / GMP reductase domain
IAFFMICD_02651 1.9e-121 drgA C Nitroreductase family
IAFFMICD_02652 1.2e-67 yqkB S Belongs to the HesB IscA family
IAFFMICD_02653 3.9e-240 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
IAFFMICD_02654 2.2e-128 K cheY-homologous receiver domain
IAFFMICD_02655 8.2e-67
IAFFMICD_02656 3.3e-172 ccpB 5.1.1.1 K lacI family
IAFFMICD_02657 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
IAFFMICD_02658 1.7e-154 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IAFFMICD_02659 3.8e-55 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IAFFMICD_02660 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAFFMICD_02661 9.8e-225 mdtG EGP Major facilitator Superfamily
IAFFMICD_02662 6.9e-150 K acetyltransferase
IAFFMICD_02663 6.8e-90
IAFFMICD_02664 5e-221 yceI G Sugar (and other) transporter
IAFFMICD_02666 5.9e-242 recJ L Single-stranded-DNA-specific exonuclease RecJ
IAFFMICD_02667 5.3e-81 recJ L Single-stranded-DNA-specific exonuclease RecJ
IAFFMICD_02668 2e-94 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAFFMICD_02669 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAFFMICD_02670 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
IAFFMICD_02671 5.3e-147 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
IAFFMICD_02672 3.3e-186
IAFFMICD_02675 1.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IAFFMICD_02676 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAFFMICD_02677 1.3e-145 tatD L hydrolase, TatD family
IAFFMICD_02678 7.7e-80 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IAFFMICD_02679 9.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
IAFFMICD_02680 6.9e-172 yqhA G Aldose 1-epimerase
IAFFMICD_02681 3e-125 T LytTr DNA-binding domain
IAFFMICD_02682 4.5e-166 2.7.13.3 T GHKL domain
IAFFMICD_02683 0.0 V ABC transporter
IAFFMICD_02684 0.0 V ABC transporter
IAFFMICD_02685 4.1e-30 K Transcriptional
IAFFMICD_02686 2.2e-65
IAFFMICD_02687 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAFFMICD_02688 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IAFFMICD_02689 9.2e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IAFFMICD_02690 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IAFFMICD_02691 8.5e-46 S Family of unknown function (DUF5322)
IAFFMICD_02692 1.1e-68 rnhA 3.1.26.4 L Ribonuclease HI
IAFFMICD_02693 1.5e-109 XK27_02070 S Nitroreductase family
IAFFMICD_02694 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAFFMICD_02695 9.7e-55
IAFFMICD_02697 1.6e-271 K Mga helix-turn-helix domain
IAFFMICD_02698 4.5e-38 nrdH O Glutaredoxin
IAFFMICD_02699 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAFFMICD_02700 1.2e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAFFMICD_02702 7.2e-115 K Transcriptional regulator
IAFFMICD_02703 7.1e-62
IAFFMICD_02704 1.6e-73 6.3.3.2 S ASCH
IAFFMICD_02705 5.9e-32
IAFFMICD_02706 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IAFFMICD_02707 4.1e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IAFFMICD_02708 1e-286 dnaK O Heat shock 70 kDa protein
IAFFMICD_02709 5.2e-99 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IAFFMICD_02710 8.4e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IAFFMICD_02711 1.6e-224 hemN H Involved in the biosynthesis of porphyrin-containing compound
IAFFMICD_02712 3.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IAFFMICD_02713 1.3e-160 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAFFMICD_02714 1.5e-141 terC P membrane
IAFFMICD_02715 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAFFMICD_02717 1e-171 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IAFFMICD_02718 1.2e-146 yunF F Protein of unknown function DUF72
IAFFMICD_02719 1.1e-91 3.6.1.55 F NUDIX domain
IAFFMICD_02720 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IAFFMICD_02721 5.3e-107 yiiE S Protein of unknown function (DUF1211)
IAFFMICD_02722 2.2e-128 cobB K Sir2 family
IAFFMICD_02723 1.2e-07
IAFFMICD_02724 5.7e-169
IAFFMICD_02725 1.9e-97 yxkA S Phosphatidylethanolamine-binding protein
IAFFMICD_02727 4.2e-162 ypuA S Protein of unknown function (DUF1002)
IAFFMICD_02728 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IAFFMICD_02729 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IAFFMICD_02730 2.8e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IAFFMICD_02738 1.3e-93 sigH K Sigma-70 region 2
IAFFMICD_02739 1.1e-297 ybeC E amino acid
IAFFMICD_02740 4.5e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IAFFMICD_02741 2.6e-194 cpoA GT4 M Glycosyltransferase, group 1 family protein
IAFFMICD_02742 2.9e-166 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAFFMICD_02743 1.2e-219 patA 2.6.1.1 E Aminotransferase
IAFFMICD_02744 5.1e-44 ykuJ S Protein of unknown function (DUF1797)
IAFFMICD_02745 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IAFFMICD_02746 2e-79 perR P Belongs to the Fur family
IAFFMICD_02747 3.1e-95
IAFFMICD_02748 5.6e-167 K sequence-specific DNA binding
IAFFMICD_02749 1.7e-282 V ABC transporter transmembrane region
IAFFMICD_02750 0.0 pepF E Oligopeptidase F
IAFFMICD_02751 5e-78 ndk 2.7.4.6 F Belongs to the NDK family
IAFFMICD_02752 1.3e-54
IAFFMICD_02753 0.0 yfgQ P E1-E2 ATPase
IAFFMICD_02754 8.8e-178 3.4.11.5 I Releases the N-terminal proline from various substrates
IAFFMICD_02755 1.8e-59
IAFFMICD_02756 1.5e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IAFFMICD_02757 1.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IAFFMICD_02758 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IAFFMICD_02759 1.2e-64
IAFFMICD_02760 3.7e-293 clcA P chloride
IAFFMICD_02761 1.7e-60
IAFFMICD_02762 9.3e-31 secG U Preprotein translocase
IAFFMICD_02763 5.4e-138 est 3.1.1.1 S Serine aminopeptidase, S33
IAFFMICD_02764 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IAFFMICD_02765 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IAFFMICD_02766 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
IAFFMICD_02767 2.4e-37
IAFFMICD_02768 1.6e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAFFMICD_02769 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IAFFMICD_02770 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IAFFMICD_02771 5.6e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IAFFMICD_02772 3.3e-146
IAFFMICD_02773 1.9e-123 S Tetratricopeptide repeat
IAFFMICD_02774 1.7e-122
IAFFMICD_02775 9.7e-71
IAFFMICD_02776 3.3e-42 rpmE2 J Ribosomal protein L31
IAFFMICD_02777 7.4e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAFFMICD_02779 1.3e-37 L Psort location Cytoplasmic, score
IAFFMICD_02780 6.8e-96 3.1.21.3 V Type I restriction modification DNA specificity domain
IAFFMICD_02781 2.6e-302 hsdM 2.1.1.72 V type I restriction-modification system
IAFFMICD_02782 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IAFFMICD_02783 4.7e-137 L Transposase and inactivated derivatives, IS30 family
IAFFMICD_02784 1.1e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IAFFMICD_02785 1.6e-219 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IAFFMICD_02786 9.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IAFFMICD_02787 3.4e-194 M Glycosyltransferase like family 2
IAFFMICD_02788 2.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
IAFFMICD_02789 1.9e-80 fld C Flavodoxin
IAFFMICD_02790 1.7e-179 yihY S Belongs to the UPF0761 family
IAFFMICD_02791 1.2e-260 S Uncharacterized protein conserved in bacteria (DUF2252)
IAFFMICD_02794 6.8e-110 K Bacterial regulatory proteins, tetR family
IAFFMICD_02795 6.2e-190 rafA 3.2.1.22 G alpha-galactosidase
IAFFMICD_02796 1.4e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IAFFMICD_02797 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IAFFMICD_02798 1.3e-48 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAFFMICD_02799 7.3e-35 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IAFFMICD_02800 8.2e-16 J Putative rRNA methylase
IAFFMICD_02801 1.6e-155 glcU U sugar transport
IAFFMICD_02802 2.3e-51 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
IAFFMICD_02803 2.7e-287 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IAFFMICD_02804 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
IAFFMICD_02805 4.5e-155 lacT K PRD domain
IAFFMICD_02806 1.4e-50 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
IAFFMICD_02807 6.6e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IAFFMICD_02808 2.5e-239 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IAFFMICD_02809 2.8e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IAFFMICD_02810 2.6e-236 pyrP F Permease
IAFFMICD_02811 1.7e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IAFFMICD_02812 2.9e-45
IAFFMICD_02813 9.4e-58
IAFFMICD_02814 5.6e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IAFFMICD_02815 7.3e-116 ydfK S Protein of unknown function (DUF554)
IAFFMICD_02816 2.2e-87
IAFFMICD_02818 2.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAFFMICD_02819 5.8e-34
IAFFMICD_02820 7e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IAFFMICD_02821 7.6e-115 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IAFFMICD_02822 1.8e-207 yaaN P Toxic anion resistance protein (TelA)
IAFFMICD_02823 2.2e-54 ydiC1 EGP Major facilitator Superfamily
IAFFMICD_02824 9.6e-183 ykcC GT2 M Glycosyl transferase family 2
IAFFMICD_02825 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
IAFFMICD_02826 6.4e-72 S GtrA-like protein
IAFFMICD_02827 4.4e-29 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IAFFMICD_02828 2.1e-152 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IAFFMICD_02829 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IAFFMICD_02830 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IAFFMICD_02831 2.6e-07
IAFFMICD_02833 3.3e-71 S Domain of unknown function (DUF3284)
IAFFMICD_02834 1.1e-256 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IAFFMICD_02835 1.1e-170 mleP S Sodium Bile acid symporter family
IAFFMICD_02836 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IAFFMICD_02837 6.8e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
IAFFMICD_02838 2.4e-71 S COG NOG38524 non supervised orthologous group
IAFFMICD_02839 2.8e-79 terS L Phage terminase, small subunit
IAFFMICD_02842 2.2e-70 S Virulence-associated protein E
IAFFMICD_02843 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IAFFMICD_02844 1.7e-47 S Phage gp6-like head-tail connector protein
IAFFMICD_02845 2.7e-280 S Phage capsid family
IAFFMICD_02846 1.4e-75 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAFFMICD_02847 9.9e-10 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAFFMICD_02848 1.3e-45 S Phage gp6-like head-tail connector protein
IAFFMICD_02849 1.6e-269 S Phage capsid family
IAFFMICD_02850 2.8e-79 terS L Phage terminase, small subunit
IAFFMICD_02851 9.8e-76 L Phage-associated protein
IAFFMICD_02852 1.9e-43
IAFFMICD_02853 6.1e-35
IAFFMICD_02854 2.5e-171 L Transposase
IAFFMICD_02855 5.4e-62 terL S overlaps another CDS with the same product name
IAFFMICD_02856 8.6e-21
IAFFMICD_02857 1e-72 terL S overlaps another CDS with the same product name
IAFFMICD_02858 1.9e-20
IAFFMICD_02859 6e-76 S Virulence-associated protein E
IAFFMICD_02860 6.4e-69 tnpB L Putative transposase DNA-binding domain
IAFFMICD_02868 1.8e-34 tnp2PF3 L Transposase DDE domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)