ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMCIFNEL_00001 1.8e-40 comP 2.7.13.3 T Histidine kinase
HMCIFNEL_00003 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
HMCIFNEL_00005 3.8e-23 yuzC
HMCIFNEL_00006 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HMCIFNEL_00007 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMCIFNEL_00008 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
HMCIFNEL_00009 3.6e-67 yueI S Protein of unknown function (DUF1694)
HMCIFNEL_00010 6.3e-38 yueH S YueH-like protein
HMCIFNEL_00011 6.6e-31 yueG S Spore germination protein gerPA/gerPF
HMCIFNEL_00012 3.9e-188 yueF S transporter activity
HMCIFNEL_00013 5.2e-71 S Protein of unknown function (DUF2283)
HMCIFNEL_00014 1.1e-23 S Protein of unknown function (DUF2642)
HMCIFNEL_00015 1.1e-95 yueE S phosphohydrolase
HMCIFNEL_00016 9.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_00017 6.6e-65 yueC S Family of unknown function (DUF5383)
HMCIFNEL_00018 0.0 esaA S type VII secretion protein EsaA
HMCIFNEL_00019 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HMCIFNEL_00020 6.4e-209 essB S WXG100 protein secretion system (Wss), protein YukC
HMCIFNEL_00021 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HMCIFNEL_00022 2.8e-45 esxA S Belongs to the WXG100 family
HMCIFNEL_00023 2.8e-227 yukF QT Transcriptional regulator
HMCIFNEL_00024 2.6e-203 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HMCIFNEL_00025 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HMCIFNEL_00026 4.2e-35 mbtH S MbtH-like protein
HMCIFNEL_00027 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCIFNEL_00028 6.8e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HMCIFNEL_00029 2.2e-311 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HMCIFNEL_00030 4.7e-224 entC 5.4.4.2 HQ Isochorismate synthase
HMCIFNEL_00031 5.2e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_00032 3.9e-167 besA S Putative esterase
HMCIFNEL_00033 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HMCIFNEL_00034 9.7e-93 bioY S Biotin biosynthesis protein
HMCIFNEL_00035 3.9e-211 yuiF S antiporter
HMCIFNEL_00036 2.2e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HMCIFNEL_00037 2e-77 yuiD S protein conserved in bacteria
HMCIFNEL_00038 6.8e-116 yuiC S protein conserved in bacteria
HMCIFNEL_00039 1.1e-26 yuiB S Putative membrane protein
HMCIFNEL_00040 1.6e-235 yumB 1.6.99.3 C NADH dehydrogenase
HMCIFNEL_00041 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HMCIFNEL_00043 1.8e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMCIFNEL_00044 6.1e-114 paiB K Putative FMN-binding domain
HMCIFNEL_00045 4.3e-49 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMCIFNEL_00046 3.7e-63 erpA S Belongs to the HesB IscA family
HMCIFNEL_00047 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMCIFNEL_00048 1e-197 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMCIFNEL_00049 3.2e-39 yuzB S Belongs to the UPF0349 family
HMCIFNEL_00050 7.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HMCIFNEL_00051 1.1e-55 yuzD S protein conserved in bacteria
HMCIFNEL_00052 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HMCIFNEL_00053 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HMCIFNEL_00054 4.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMCIFNEL_00055 3.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HMCIFNEL_00056 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HMCIFNEL_00057 8.5e-198 yutH S Spore coat protein
HMCIFNEL_00058 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HMCIFNEL_00059 3.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMCIFNEL_00060 1e-75 yutE S Protein of unknown function DUF86
HMCIFNEL_00061 1.1e-46 yutD S protein conserved in bacteria
HMCIFNEL_00062 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMCIFNEL_00063 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HMCIFNEL_00064 1.3e-195 lytH M Peptidase, M23
HMCIFNEL_00065 6.6e-131 yunB S Sporulation protein YunB (Spo_YunB)
HMCIFNEL_00066 9.2e-44 yunC S Domain of unknown function (DUF1805)
HMCIFNEL_00067 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMCIFNEL_00068 5.9e-141 yunE S membrane transporter protein
HMCIFNEL_00069 1.3e-170 yunF S Protein of unknown function DUF72
HMCIFNEL_00070 6.6e-46 yunG
HMCIFNEL_00071 6.2e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HMCIFNEL_00072 3.2e-300 pucR QT COG2508 Regulator of polyketide synthase expression
HMCIFNEL_00073 3.9e-235 pbuX F Permease family
HMCIFNEL_00074 1.5e-220 pbuX F xanthine
HMCIFNEL_00075 3.5e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HMCIFNEL_00076 1e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HMCIFNEL_00078 9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HMCIFNEL_00079 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HMCIFNEL_00080 4.3e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HMCIFNEL_00081 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HMCIFNEL_00082 1.5e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HMCIFNEL_00083 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HMCIFNEL_00084 2.2e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HMCIFNEL_00085 3.8e-167 bsn L Ribonuclease
HMCIFNEL_00086 1.9e-23 S branched-chain amino acid
HMCIFNEL_00087 9.3e-74 azlC E AzlC protein
HMCIFNEL_00088 1.2e-157 gntR9 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCIFNEL_00089 8.8e-36 L COG3666 Transposase and inactivated derivatives
HMCIFNEL_00090 9.5e-67 L COG3666 Transposase and inactivated derivatives
HMCIFNEL_00091 4.1e-42 S B3/4 domain
HMCIFNEL_00092 1.8e-170 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
HMCIFNEL_00093 1.3e-22 I Fatty acid desaturase
HMCIFNEL_00094 9e-80 I Fatty acid desaturase
HMCIFNEL_00096 1.5e-195 msmX P Belongs to the ABC transporter superfamily
HMCIFNEL_00097 7.3e-135 yurK K UTRA
HMCIFNEL_00098 9e-148 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HMCIFNEL_00099 1.5e-152 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HMCIFNEL_00100 1.1e-62 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HMCIFNEL_00101 5.7e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HMCIFNEL_00102 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HMCIFNEL_00103 1.9e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HMCIFNEL_00105 1e-41
HMCIFNEL_00106 1.1e-72 L Molecular Function DNA binding, Biological Process DNA recombination
HMCIFNEL_00107 2.8e-62 L Molecular Function DNA binding, Biological Process DNA recombination
HMCIFNEL_00108 1.9e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCIFNEL_00109 3.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMCIFNEL_00110 3.5e-271 sufB O FeS cluster assembly
HMCIFNEL_00111 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HMCIFNEL_00112 7.9e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMCIFNEL_00113 9.1e-245 sufD O assembly protein SufD
HMCIFNEL_00114 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HMCIFNEL_00115 5.6e-46 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HMCIFNEL_00116 1.8e-145 metQ P Belongs to the NlpA lipoprotein family
HMCIFNEL_00117 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HMCIFNEL_00118 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMCIFNEL_00119 3.2e-56 yusD S SCP-2 sterol transfer family
HMCIFNEL_00120 1.2e-54 traF CO Thioredoxin
HMCIFNEL_00121 1.4e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HMCIFNEL_00122 2.4e-39 yusG S Protein of unknown function (DUF2553)
HMCIFNEL_00123 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HMCIFNEL_00124 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HMCIFNEL_00125 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HMCIFNEL_00126 3.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HMCIFNEL_00127 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HMCIFNEL_00128 8.1e-09 S YuzL-like protein
HMCIFNEL_00129 1.2e-163 fadM E Proline dehydrogenase
HMCIFNEL_00130 5.1e-40
HMCIFNEL_00131 1.6e-52 yusN M Coat F domain
HMCIFNEL_00132 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HMCIFNEL_00133 4.2e-292 yusP P Major facilitator superfamily
HMCIFNEL_00134 1.8e-63 yusQ S Tautomerase enzyme
HMCIFNEL_00135 2.9e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_00136 8.2e-157 yusT K LysR substrate binding domain
HMCIFNEL_00137 6.6e-47 yusU S Protein of unknown function (DUF2573)
HMCIFNEL_00138 1e-153 yusV 3.6.3.34 HP ABC transporter
HMCIFNEL_00139 3.3e-66 S YusW-like protein
HMCIFNEL_00140 1.6e-300 pepF2 E COG1164 Oligoendopeptidase F
HMCIFNEL_00141 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_00142 2.7e-79 dps P Ferritin-like domain
HMCIFNEL_00143 4.4e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMCIFNEL_00144 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_00145 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
HMCIFNEL_00146 4.8e-157 yuxN K Transcriptional regulator
HMCIFNEL_00147 9.6e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMCIFNEL_00148 3.9e-24 S Protein of unknown function (DUF3970)
HMCIFNEL_00149 2.6e-245 gerAA EG Spore germination protein
HMCIFNEL_00150 3.8e-196 gerAB E Spore germination protein
HMCIFNEL_00151 5e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
HMCIFNEL_00152 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMCIFNEL_00153 1.6e-186 vraS 2.7.13.3 T Histidine kinase
HMCIFNEL_00154 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HMCIFNEL_00155 1.2e-123 liaG S Putative adhesin
HMCIFNEL_00156 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HMCIFNEL_00157 7.3e-62 liaI S membrane
HMCIFNEL_00158 1.4e-226 yvqJ EGP Major facilitator Superfamily
HMCIFNEL_00159 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
HMCIFNEL_00160 2.7e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HMCIFNEL_00161 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_00162 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HMCIFNEL_00163 7.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_00164 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HMCIFNEL_00165 0.0 T PhoQ Sensor
HMCIFNEL_00166 8.1e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_00167 3.6e-22
HMCIFNEL_00168 4e-96 yvrI K RNA polymerase
HMCIFNEL_00169 6.9e-19 S YvrJ protein family
HMCIFNEL_00170 1.4e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
HMCIFNEL_00171 1.3e-64 yvrL S Regulatory protein YrvL
HMCIFNEL_00172 1.2e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HMCIFNEL_00173 2.1e-123 macB V ABC transporter, ATP-binding protein
HMCIFNEL_00174 6.9e-175 M Efflux transporter rnd family, mfp subunit
HMCIFNEL_00175 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HMCIFNEL_00176 3.8e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_00177 1.3e-180 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_00178 2.6e-177 fhuD P ABC transporter
HMCIFNEL_00179 4.9e-236 yvsH E Arginine ornithine antiporter
HMCIFNEL_00180 6.5e-16 S Small spore protein J (Spore_SspJ)
HMCIFNEL_00181 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HMCIFNEL_00182 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMCIFNEL_00183 2e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HMCIFNEL_00184 1.4e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HMCIFNEL_00185 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HMCIFNEL_00186 3.2e-155 yvgN S reductase
HMCIFNEL_00187 5.4e-86 yvgO
HMCIFNEL_00188 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HMCIFNEL_00189 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HMCIFNEL_00190 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HMCIFNEL_00191 0.0 helD 3.6.4.12 L DNA helicase
HMCIFNEL_00192 4.1e-107 yvgT S membrane
HMCIFNEL_00193 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
HMCIFNEL_00194 2.7e-104 bdbD O Thioredoxin
HMCIFNEL_00195 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HMCIFNEL_00196 0.0 copA 3.6.3.54 P P-type ATPase
HMCIFNEL_00197 5.9e-29 copZ P Copper resistance protein CopZ
HMCIFNEL_00198 2.2e-48 csoR S transcriptional
HMCIFNEL_00199 4e-195 yvaA 1.1.1.371 S Oxidoreductase
HMCIFNEL_00200 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMCIFNEL_00201 0.0 yvaC S Fusaric acid resistance protein-like
HMCIFNEL_00202 1.3e-72 yvaD S Family of unknown function (DUF5360)
HMCIFNEL_00203 2.4e-54 yvaE P Small Multidrug Resistance protein
HMCIFNEL_00204 4.3e-98 K Bacterial regulatory proteins, tetR family
HMCIFNEL_00205 8.5e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_00207 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HMCIFNEL_00208 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMCIFNEL_00209 9.6e-143 est 3.1.1.1 S Carboxylesterase
HMCIFNEL_00210 2.4e-23 secG U Preprotein translocase subunit SecG
HMCIFNEL_00211 1.5e-151 yvaM S Serine aminopeptidase, S33
HMCIFNEL_00212 9.8e-36 yvzC K Transcriptional
HMCIFNEL_00213 4e-69 K transcriptional
HMCIFNEL_00214 1.5e-68 yvaO K Cro/C1-type HTH DNA-binding domain
HMCIFNEL_00215 2.2e-54 yodB K transcriptional
HMCIFNEL_00216 1.2e-19 NT chemotaxis protein
HMCIFNEL_00217 2.2e-170 NT chemotaxis protein
HMCIFNEL_00218 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HMCIFNEL_00219 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMCIFNEL_00220 1.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HMCIFNEL_00221 2.7e-208 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HMCIFNEL_00222 7.4e-60 yvbF K Belongs to the GbsR family
HMCIFNEL_00223 7.9e-13 S Sporulation delaying protein SdpA
HMCIFNEL_00224 4.9e-171
HMCIFNEL_00225 4.4e-08
HMCIFNEL_00226 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HMCIFNEL_00227 4.5e-45 sdpR K transcriptional
HMCIFNEL_00228 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HMCIFNEL_00229 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMCIFNEL_00230 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HMCIFNEL_00231 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HMCIFNEL_00232 3.5e-97 yvbF K Belongs to the GbsR family
HMCIFNEL_00233 6e-101 yvbG U UPF0056 membrane protein
HMCIFNEL_00234 1.9e-112 yvbH S YvbH-like oligomerisation region
HMCIFNEL_00235 2.2e-120 exoY M Membrane
HMCIFNEL_00236 6.2e-252 tcaA S response to antibiotic
HMCIFNEL_00237 9.1e-75 yvbK 3.1.3.25 K acetyltransferase
HMCIFNEL_00238 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMCIFNEL_00239 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HMCIFNEL_00240 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMCIFNEL_00241 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMCIFNEL_00242 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMCIFNEL_00243 1.3e-182 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HMCIFNEL_00244 4.8e-252 araE EGP Major facilitator Superfamily
HMCIFNEL_00245 2.1e-202 araR K transcriptional
HMCIFNEL_00246 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMCIFNEL_00247 6.7e-159 yvbU K Transcriptional regulator
HMCIFNEL_00248 2.7e-155 yvbV EG EamA-like transporter family
HMCIFNEL_00249 1.4e-240 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HMCIFNEL_00250 4.7e-188 yvbX S Glycosyl hydrolase
HMCIFNEL_00251 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HMCIFNEL_00252 1e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HMCIFNEL_00253 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HMCIFNEL_00254 1.6e-45 S Protein of unknown function (DUF2812)
HMCIFNEL_00255 2e-31 K Transcriptional regulator PadR-like family
HMCIFNEL_00256 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMCIFNEL_00257 7.1e-198 desK 2.7.13.3 T Histidine kinase
HMCIFNEL_00258 5.3e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HMCIFNEL_00259 8.1e-160 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HMCIFNEL_00260 9.8e-157 rsbQ S Alpha/beta hydrolase family
HMCIFNEL_00261 1.5e-193 rsbU 3.1.3.3 T response regulator
HMCIFNEL_00262 3.2e-250 galA 3.2.1.89 G arabinogalactan
HMCIFNEL_00263 0.0 lacA 3.2.1.23 G beta-galactosidase
HMCIFNEL_00264 7.2e-150 ganQ P transport
HMCIFNEL_00265 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
HMCIFNEL_00266 8.8e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
HMCIFNEL_00267 1.8e-184 lacR K Transcriptional regulator
HMCIFNEL_00268 1e-112 yvfI K COG2186 Transcriptional regulators
HMCIFNEL_00269 5.7e-308 yvfH C L-lactate permease
HMCIFNEL_00270 2.5e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HMCIFNEL_00271 1e-31 yvfG S YvfG protein
HMCIFNEL_00272 5.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
HMCIFNEL_00273 6.2e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HMCIFNEL_00274 2.1e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HMCIFNEL_00275 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HMCIFNEL_00276 3.8e-255 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMCIFNEL_00277 4.6e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HMCIFNEL_00278 1e-201 epsI GM pyruvyl transferase
HMCIFNEL_00279 2.9e-193 epsH GT2 S Glycosyltransferase like family 2
HMCIFNEL_00280 5.4e-206 epsG S EpsG family
HMCIFNEL_00281 2.9e-218 epsF GT4 M Glycosyl transferases group 1
HMCIFNEL_00282 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMCIFNEL_00283 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
HMCIFNEL_00284 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HMCIFNEL_00285 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HMCIFNEL_00286 2.2e-120 ywqC M biosynthesis protein
HMCIFNEL_00287 3.1e-75 slr K transcriptional
HMCIFNEL_00288 5.3e-278 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HMCIFNEL_00290 1.7e-92 padC Q Phenolic acid decarboxylase
HMCIFNEL_00291 4.2e-72 MA20_18690 S Protein of unknown function (DUF3237)
HMCIFNEL_00292 8.4e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMCIFNEL_00293 5.9e-263 pbpE V Beta-lactamase
HMCIFNEL_00294 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HMCIFNEL_00295 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HMCIFNEL_00296 3.3e-294 yveA E amino acid
HMCIFNEL_00297 1.4e-104 yvdT K Transcriptional regulator
HMCIFNEL_00298 1.6e-49 ykkC P Small Multidrug Resistance protein
HMCIFNEL_00299 2.1e-49 sugE P Small Multidrug Resistance protein
HMCIFNEL_00300 1.3e-72 yvdQ S Protein of unknown function (DUF3231)
HMCIFNEL_00302 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMCIFNEL_00303 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HMCIFNEL_00304 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HMCIFNEL_00305 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HMCIFNEL_00306 1.4e-153 malA S Protein of unknown function (DUF1189)
HMCIFNEL_00307 9.5e-147 malD P transport
HMCIFNEL_00308 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
HMCIFNEL_00309 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HMCIFNEL_00310 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HMCIFNEL_00311 3.3e-172 yvdE K Transcriptional regulator
HMCIFNEL_00312 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HMCIFNEL_00313 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HMCIFNEL_00314 3.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HMCIFNEL_00315 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HMCIFNEL_00316 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMCIFNEL_00317 1.6e-302 yxdM V ABC transporter (permease)
HMCIFNEL_00318 4.6e-23 yxdM V ABC transporter (permease)
HMCIFNEL_00319 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HMCIFNEL_00320 7.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HMCIFNEL_00321 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_00322 2.8e-31
HMCIFNEL_00323 2.2e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HMCIFNEL_00324 1.6e-36 crh G Phosphocarrier protein Chr
HMCIFNEL_00325 4.1e-170 whiA K May be required for sporulation
HMCIFNEL_00326 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMCIFNEL_00327 5.7e-166 rapZ S Displays ATPase and GTPase activities
HMCIFNEL_00328 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HMCIFNEL_00329 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMCIFNEL_00330 1.4e-97 usp CBM50 M protein conserved in bacteria
HMCIFNEL_00331 1e-276 S COG0457 FOG TPR repeat
HMCIFNEL_00332 0.0 msbA2 3.6.3.44 V ABC transporter
HMCIFNEL_00334 0.0
HMCIFNEL_00335 4.7e-118
HMCIFNEL_00336 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HMCIFNEL_00337 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMCIFNEL_00338 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMCIFNEL_00339 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMCIFNEL_00340 1.8e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HMCIFNEL_00341 3.8e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMCIFNEL_00342 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMCIFNEL_00343 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMCIFNEL_00344 3.8e-139 yvpB NU protein conserved in bacteria
HMCIFNEL_00345 1.5e-118 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HMCIFNEL_00346 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HMCIFNEL_00347 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HMCIFNEL_00348 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
HMCIFNEL_00349 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMCIFNEL_00350 2.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMCIFNEL_00351 8.3e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMCIFNEL_00352 1.2e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMCIFNEL_00353 3.6e-134 yvoA K transcriptional
HMCIFNEL_00354 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HMCIFNEL_00355 4.2e-83 adcR K helix_turn_helix multiple antibiotic resistance protein
HMCIFNEL_00356 3.8e-229 cypX 1.14.15.13 C Cytochrome P450
HMCIFNEL_00357 1.8e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HMCIFNEL_00358 7.4e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
HMCIFNEL_00359 2.7e-203 yvmA EGP Major facilitator Superfamily
HMCIFNEL_00360 1.2e-50 yvlD S Membrane
HMCIFNEL_00361 2.6e-26 pspB KT PspC domain
HMCIFNEL_00362 2.4e-166 yvlB S Putative adhesin
HMCIFNEL_00363 8e-49 yvlA
HMCIFNEL_00364 5.7e-33 yvkN
HMCIFNEL_00365 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HMCIFNEL_00366 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMCIFNEL_00367 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMCIFNEL_00368 1.2e-30 csbA S protein conserved in bacteria
HMCIFNEL_00369 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HMCIFNEL_00370 1e-99 yvkB K Transcriptional regulator
HMCIFNEL_00371 3.3e-226 yvkA EGP Major facilitator Superfamily
HMCIFNEL_00372 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMCIFNEL_00373 5.3e-56 swrA S Swarming motility protein
HMCIFNEL_00374 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HMCIFNEL_00375 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HMCIFNEL_00376 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HMCIFNEL_00377 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HMCIFNEL_00378 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HMCIFNEL_00379 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMCIFNEL_00380 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMCIFNEL_00381 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMCIFNEL_00382 4.6e-51
HMCIFNEL_00383 1.9e-08 fliT S bacterial-type flagellum organization
HMCIFNEL_00384 1.9e-68 fliS N flagellar protein FliS
HMCIFNEL_00385 7.7e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HMCIFNEL_00386 1.2e-52 flaG N flagellar protein FlaG
HMCIFNEL_00387 9.4e-115 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HMCIFNEL_00388 1.7e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HMCIFNEL_00389 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HMCIFNEL_00390 5.7e-50 yviE
HMCIFNEL_00391 7.8e-155 flgL N Belongs to the bacterial flagellin family
HMCIFNEL_00392 4.6e-264 flgK N flagellar hook-associated protein
HMCIFNEL_00393 2.4e-78 flgN NOU FlgN protein
HMCIFNEL_00394 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HMCIFNEL_00395 7e-74 yvyF S flagellar protein
HMCIFNEL_00396 2.7e-129 comFC S Phosphoribosyl transferase domain
HMCIFNEL_00397 5.7e-46 comFB S Late competence development protein ComFB
HMCIFNEL_00398 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HMCIFNEL_00399 2.1e-154 degV S protein conserved in bacteria
HMCIFNEL_00400 1e-125 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMCIFNEL_00401 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HMCIFNEL_00402 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HMCIFNEL_00403 6e-163 yvhJ K Transcriptional regulator
HMCIFNEL_00404 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HMCIFNEL_00405 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HMCIFNEL_00406 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HMCIFNEL_00407 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
HMCIFNEL_00408 5.4e-262 tuaE M Teichuronic acid biosynthesis protein
HMCIFNEL_00409 7.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMCIFNEL_00410 1.7e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HMCIFNEL_00411 5.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMCIFNEL_00412 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HMCIFNEL_00413 5.6e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMCIFNEL_00414 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HMCIFNEL_00415 6e-38
HMCIFNEL_00416 4e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HMCIFNEL_00417 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMCIFNEL_00418 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMCIFNEL_00419 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMCIFNEL_00420 1.4e-256 ggaA M Glycosyltransferase like family 2
HMCIFNEL_00422 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMCIFNEL_00423 2.2e-277 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMCIFNEL_00424 1.1e-150 tagG GM Transport permease protein
HMCIFNEL_00425 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HMCIFNEL_00426 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HMCIFNEL_00427 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HMCIFNEL_00428 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMCIFNEL_00429 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HMCIFNEL_00430 3.5e-260
HMCIFNEL_00431 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMCIFNEL_00432 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HMCIFNEL_00433 5.3e-262 gerBA EG Spore germination protein
HMCIFNEL_00434 1.3e-191 gerBB E Spore germination protein
HMCIFNEL_00435 1.4e-206 gerAC S Spore germination protein
HMCIFNEL_00436 1.7e-246 ywtG EGP Major facilitator Superfamily
HMCIFNEL_00437 2.4e-170 ywtF K Transcriptional regulator
HMCIFNEL_00438 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HMCIFNEL_00439 1.3e-72 L Integrase core domain
HMCIFNEL_00440 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_00441 7.1e-101 yxaF K Transcriptional regulator
HMCIFNEL_00442 9.6e-194 yxaG 1.13.11.24 S AraC-like ligand binding domain
HMCIFNEL_00443 7.4e-225 P Protein of unknown function (DUF418)
HMCIFNEL_00444 2.4e-75 yxaI S membrane protein domain
HMCIFNEL_00445 7.2e-60 S Family of unknown function (DUF5391)
HMCIFNEL_00446 9.9e-92 S PQQ-like domain
HMCIFNEL_00447 4e-12 yxaI S membrane protein domain
HMCIFNEL_00448 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HMCIFNEL_00449 2.7e-208 yxbF K Bacterial regulatory proteins, tetR family
HMCIFNEL_00450 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
HMCIFNEL_00452 0.0 htpG O Molecular chaperone. Has ATPase activity
HMCIFNEL_00453 2.8e-244 csbC EGP Major facilitator Superfamily
HMCIFNEL_00454 2.4e-47 yxcD S Protein of unknown function (DUF2653)
HMCIFNEL_00456 1.9e-175 iolS C Aldo keto reductase
HMCIFNEL_00457 9.5e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HMCIFNEL_00458 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMCIFNEL_00459 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HMCIFNEL_00460 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HMCIFNEL_00461 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HMCIFNEL_00462 8.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HMCIFNEL_00463 6.2e-233 iolF EGP Major facilitator Superfamily
HMCIFNEL_00464 1.8e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HMCIFNEL_00465 3.3e-166 iolH G Xylose isomerase-like TIM barrel
HMCIFNEL_00466 2.1e-146 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HMCIFNEL_00467 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HMCIFNEL_00468 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_00469 1.5e-180 T PhoQ Sensor
HMCIFNEL_00470 9.7e-138 yxdL V ABC transporter, ATP-binding protein
HMCIFNEL_00471 0.0 yxdM V ABC transporter (permease)
HMCIFNEL_00472 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HMCIFNEL_00473 2.3e-176 fhuD P ABC transporter
HMCIFNEL_00474 8.5e-69
HMCIFNEL_00475 5.6e-16 yxeD
HMCIFNEL_00476 1.3e-20 yxeE
HMCIFNEL_00479 1.4e-150 yidA S hydrolases of the HAD superfamily
HMCIFNEL_00480 1e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HMCIFNEL_00481 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMCIFNEL_00482 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMCIFNEL_00483 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HMCIFNEL_00484 2.9e-106 yxeN P COG0765 ABC-type amino acid transport system, permease component
HMCIFNEL_00485 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HMCIFNEL_00486 2.7e-213 yxeP 3.5.1.47 E hydrolase activity
HMCIFNEL_00487 3.4e-247 yxeQ S MmgE/PrpD family
HMCIFNEL_00488 7.1e-198 eutH E Ethanolamine utilisation protein, EutH
HMCIFNEL_00489 2e-152 yxxB S Domain of Unknown Function (DUF1206)
HMCIFNEL_00490 1.8e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HMCIFNEL_00491 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMCIFNEL_00492 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMCIFNEL_00493 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HMCIFNEL_00494 6.3e-249 lysP E amino acid
HMCIFNEL_00495 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HMCIFNEL_00496 3.3e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HMCIFNEL_00497 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HMCIFNEL_00498 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
HMCIFNEL_00499 2.8e-76 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HMCIFNEL_00500 1.4e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HMCIFNEL_00501 6.4e-77 L NgoFVII restriction endonuclease
HMCIFNEL_00502 1.7e-96 S GTP binding
HMCIFNEL_00503 4.9e-183 2.1.1.37 H C-5 cytosine-specific DNA methylase
HMCIFNEL_00504 2.8e-49 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HMCIFNEL_00505 1e-20 S Domain of unknown function (DUF5082)
HMCIFNEL_00506 4.7e-39 yxiC S Family of unknown function (DUF5344)
HMCIFNEL_00507 1.1e-303 S nuclease activity
HMCIFNEL_00508 1.1e-77 S SMI1 / KNR4 family
HMCIFNEL_00509 2.9e-40
HMCIFNEL_00510 5.9e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMCIFNEL_00511 2.9e-173 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMCIFNEL_00512 1.1e-72 yxiE T Belongs to the universal stress protein A family
HMCIFNEL_00513 1.4e-162 yxxF EG EamA-like transporter family
HMCIFNEL_00514 0.0 wapA M COG3209 Rhs family protein
HMCIFNEL_00515 4.1e-14 yxiJ S YxiJ-like protein
HMCIFNEL_00516 6.1e-80 wapA M COG3209 Rhs family protein
HMCIFNEL_00517 3.5e-54
HMCIFNEL_00519 7.2e-139
HMCIFNEL_00520 4e-93 S Protein of unknown function (DUF4240)
HMCIFNEL_00521 4.9e-76
HMCIFNEL_00522 8.4e-45
HMCIFNEL_00523 4.3e-68 yxiG
HMCIFNEL_00524 3.4e-52 yxxG
HMCIFNEL_00525 1.9e-38 S Protein of unknown function (DUF2750)
HMCIFNEL_00526 5.3e-16 yxiG
HMCIFNEL_00527 8.3e-13 yxiG
HMCIFNEL_00528 6.5e-135
HMCIFNEL_00529 3.9e-84 yxiI S Protein of unknown function (DUF2716)
HMCIFNEL_00530 7.7e-43 yxiJ S YxiJ-like protein
HMCIFNEL_00533 6.6e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HMCIFNEL_00534 8.1e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HMCIFNEL_00535 2.3e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
HMCIFNEL_00536 1.2e-110
HMCIFNEL_00537 8.8e-139 licT K transcriptional antiterminator
HMCIFNEL_00538 3.3e-143 exoK GH16 M licheninase activity
HMCIFNEL_00539 6.6e-224 citH C Citrate transporter
HMCIFNEL_00540 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HMCIFNEL_00541 3e-47 yxiS
HMCIFNEL_00542 1.2e-102 T Domain of unknown function (DUF4163)
HMCIFNEL_00543 2.1e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMCIFNEL_00546 1.8e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMCIFNEL_00547 8.7e-90 yhaK S Putative zincin peptidase
HMCIFNEL_00548 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HMCIFNEL_00549 1e-113 hpr K Negative regulator of protease production and sporulation
HMCIFNEL_00550 7e-39 yhaH S YtxH-like protein
HMCIFNEL_00551 3.6e-80 trpP S Tryptophan transporter TrpP
HMCIFNEL_00552 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMCIFNEL_00553 1.1e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HMCIFNEL_00554 4.6e-137 ecsA V transporter (ATP-binding protein)
HMCIFNEL_00555 1.6e-214 ecsB U ABC transporter
HMCIFNEL_00556 1.4e-114 ecsC S EcsC protein family
HMCIFNEL_00557 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HMCIFNEL_00558 1.9e-245 yhfA C membrane
HMCIFNEL_00559 1.9e-34 1.15.1.2 C Rubrerythrin
HMCIFNEL_00560 8.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HMCIFNEL_00561 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMCIFNEL_00562 6.3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HMCIFNEL_00563 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HMCIFNEL_00564 1.2e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HMCIFNEL_00565 4.6e-100 yhgD K Transcriptional regulator
HMCIFNEL_00566 1.7e-214 yhgE S YhgE Pip N-terminal domain protein
HMCIFNEL_00567 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMCIFNEL_00568 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
HMCIFNEL_00569 6.6e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HMCIFNEL_00570 3.7e-72 3.4.13.21 S ASCH
HMCIFNEL_00571 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMCIFNEL_00572 3.4e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HMCIFNEL_00573 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HMCIFNEL_00574 2.9e-111 yhfK GM NmrA-like family
HMCIFNEL_00575 3.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HMCIFNEL_00576 1.4e-63 yhfM
HMCIFNEL_00577 2.5e-239 yhfN 3.4.24.84 O Peptidase M48
HMCIFNEL_00578 2e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HMCIFNEL_00579 6.2e-76 VY92_01935 K acetyltransferase
HMCIFNEL_00580 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HMCIFNEL_00581 2.5e-154 yfmC M Periplasmic binding protein
HMCIFNEL_00582 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HMCIFNEL_00583 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
HMCIFNEL_00584 9e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HMCIFNEL_00585 5e-91 bioY S BioY family
HMCIFNEL_00586 5.4e-181 hemAT NT chemotaxis protein
HMCIFNEL_00587 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HMCIFNEL_00588 1.6e-188 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HMCIFNEL_00589 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_00590 1.3e-32 yhzC S IDEAL
HMCIFNEL_00591 4.2e-109 comK K Competence transcription factor
HMCIFNEL_00592 2.9e-165 IQ Enoyl-(Acyl carrier protein) reductase
HMCIFNEL_00593 1.1e-40 yhjA S Excalibur calcium-binding domain
HMCIFNEL_00594 7.5e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMCIFNEL_00595 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HMCIFNEL_00596 6.7e-60 yhjD
HMCIFNEL_00597 9.1e-110 yhjE S SNARE associated Golgi protein
HMCIFNEL_00598 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HMCIFNEL_00599 7.3e-283 yhjG CH FAD binding domain
HMCIFNEL_00600 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HMCIFNEL_00601 7.6e-214 glcP G Major Facilitator Superfamily
HMCIFNEL_00602 1.3e-198 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HMCIFNEL_00603 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HMCIFNEL_00604 1.9e-112 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HMCIFNEL_00605 3.8e-128 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HMCIFNEL_00606 5.9e-188 yhjM 5.1.1.1 K Transcriptional regulator
HMCIFNEL_00607 1.9e-201 abrB S membrane
HMCIFNEL_00608 2.2e-213 EGP Transmembrane secretion effector
HMCIFNEL_00609 0.0 S Sugar transport-related sRNA regulator N-term
HMCIFNEL_00610 2.2e-78 yhjR S Rubrerythrin
HMCIFNEL_00611 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HMCIFNEL_00612 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMCIFNEL_00613 9.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMCIFNEL_00614 0.0 sbcC L COG0419 ATPase involved in DNA repair
HMCIFNEL_00615 3.1e-47 yisB V COG1403 Restriction endonuclease
HMCIFNEL_00616 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HMCIFNEL_00617 3e-66 gerPE S Spore germination protein GerPE
HMCIFNEL_00618 6.3e-24 gerPD S Spore germination protein
HMCIFNEL_00619 5.3e-54 gerPC S Spore germination protein
HMCIFNEL_00620 4e-34 gerPB S cell differentiation
HMCIFNEL_00621 1.9e-33 gerPA S Spore germination protein
HMCIFNEL_00622 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HMCIFNEL_00623 2.7e-174 cotH M Spore Coat
HMCIFNEL_00624 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HMCIFNEL_00625 3e-57 yisL S UPF0344 protein
HMCIFNEL_00626 0.0 wprA O Belongs to the peptidase S8 family
HMCIFNEL_00627 4e-101 yisN S Protein of unknown function (DUF2777)
HMCIFNEL_00628 0.0 asnO 6.3.5.4 E Asparagine synthase
HMCIFNEL_00629 1.1e-118 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HMCIFNEL_00630 1.5e-242 yisQ V Mate efflux family protein
HMCIFNEL_00631 3.5e-160 yisR K Transcriptional regulator
HMCIFNEL_00632 5.5e-181 purR K helix_turn _helix lactose operon repressor
HMCIFNEL_00633 4.4e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HMCIFNEL_00634 7e-92 yisT S DinB family
HMCIFNEL_00635 1.2e-106 argO S Lysine exporter protein LysE YggA
HMCIFNEL_00636 7.6e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCIFNEL_00637 2e-35 mcbG S Pentapeptide repeats (9 copies)
HMCIFNEL_00638 1.3e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMCIFNEL_00639 6e-111 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HMCIFNEL_00640 4.3e-163 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HMCIFNEL_00641 5.4e-52 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HMCIFNEL_00642 1.5e-57 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HMCIFNEL_00643 2.7e-62 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HMCIFNEL_00644 2.5e-121 comB 3.1.3.71 H Belongs to the ComB family
HMCIFNEL_00645 3.5e-140 yitD 4.4.1.19 S synthase
HMCIFNEL_00646 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMCIFNEL_00647 1e-144 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HMCIFNEL_00648 1.5e-48 urtA E Receptor family ligand binding region
HMCIFNEL_00649 5.5e-23 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCIFNEL_00650 5.8e-53 yebE S Protein of unknown function (DUF533)
HMCIFNEL_00651 9.3e-26 S Bacterial PH domain
HMCIFNEL_00652 3.7e-65 tcaB EGP Major facilitator Superfamily
HMCIFNEL_00653 5.1e-78 ybiO M mechanosensitive ion channel
HMCIFNEL_00654 1.3e-44 yfhJ S WVELL protein
HMCIFNEL_00655 6.2e-20 sspK S reproduction
HMCIFNEL_00656 1.6e-208 yfhI EGP Major facilitator Superfamily
HMCIFNEL_00658 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HMCIFNEL_00659 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HMCIFNEL_00660 7.9e-171 yfhF S nucleoside-diphosphate sugar epimerase
HMCIFNEL_00662 2.1e-25 yfhD S YfhD-like protein
HMCIFNEL_00663 3.9e-107 yfhC C nitroreductase
HMCIFNEL_00664 5.3e-164 yfhB 5.3.3.17 S PhzF family
HMCIFNEL_00665 4.4e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_00666 9.9e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_00667 6.3e-174 yfiY P ABC transporter substrate-binding protein
HMCIFNEL_00668 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMCIFNEL_00669 4.9e-79 yfiV K transcriptional
HMCIFNEL_00670 2.6e-283 yfiU EGP Major facilitator Superfamily
HMCIFNEL_00671 1.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
HMCIFNEL_00672 9.3e-195 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HMCIFNEL_00673 1.3e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HMCIFNEL_00674 8.3e-99 padR K transcriptional
HMCIFNEL_00675 8.9e-52 J Acetyltransferase (GNAT) domain
HMCIFNEL_00676 1.8e-204 V COG0842 ABC-type multidrug transport system, permease component
HMCIFNEL_00677 3.3e-209 V ABC-2 family transporter protein
HMCIFNEL_00678 1.5e-169 V ABC transporter, ATP-binding protein
HMCIFNEL_00679 5.4e-113 KT LuxR family transcriptional regulator
HMCIFNEL_00680 1.8e-212 yxjM T Histidine kinase
HMCIFNEL_00682 1.1e-230 S Oxidoreductase
HMCIFNEL_00683 3.2e-183 G Xylose isomerase
HMCIFNEL_00684 3.2e-259 iolT EGP Major facilitator Superfamily
HMCIFNEL_00685 3e-173 K AraC-like ligand binding domain
HMCIFNEL_00686 2.8e-162 yfiE 1.13.11.2 S glyoxalase
HMCIFNEL_00687 6.4e-64 mhqP S DoxX
HMCIFNEL_00688 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMCIFNEL_00689 1.1e-306 yfiB3 V ABC transporter
HMCIFNEL_00690 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMCIFNEL_00691 7.9e-140 glvR K Helix-turn-helix domain, rpiR family
HMCIFNEL_00692 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HMCIFNEL_00693 1.1e-44 yfjA S Belongs to the WXG100 family
HMCIFNEL_00694 6.8e-186 yfjB
HMCIFNEL_00695 1.5e-143 yfjC
HMCIFNEL_00696 6.9e-101 yfjD S Family of unknown function (DUF5381)
HMCIFNEL_00697 5.2e-56 yfjF S UPF0060 membrane protein
HMCIFNEL_00698 1.2e-25 sspH S Belongs to the SspH family
HMCIFNEL_00699 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HMCIFNEL_00700 1.2e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMCIFNEL_00701 4.3e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMCIFNEL_00702 8.5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMCIFNEL_00703 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMCIFNEL_00704 6.6e-29 yfjL
HMCIFNEL_00705 1.9e-85 yfjM S Psort location Cytoplasmic, score
HMCIFNEL_00706 9.3e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMCIFNEL_00707 5.1e-44 S YfzA-like protein
HMCIFNEL_00708 5.6e-138 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCIFNEL_00709 1.7e-119 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCIFNEL_00710 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HMCIFNEL_00711 8e-182 corA P Mediates influx of magnesium ions
HMCIFNEL_00712 1.4e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HMCIFNEL_00713 3.8e-153 pdaA G deacetylase
HMCIFNEL_00714 1.1e-26 yfjT
HMCIFNEL_00715 5.4e-222 yfkA S YfkB-like domain
HMCIFNEL_00716 2.3e-148 yfkC M Mechanosensitive ion channel
HMCIFNEL_00717 2e-146 yfkD S YfkD-like protein
HMCIFNEL_00718 6.1e-183 cax P COG0387 Ca2 H antiporter
HMCIFNEL_00719 1.7e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HMCIFNEL_00721 1.3e-143 yihY S Belongs to the UPF0761 family
HMCIFNEL_00722 2.4e-50 yfkI S gas vesicle protein
HMCIFNEL_00723 6.3e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMCIFNEL_00724 1.3e-28 yfkK S Belongs to the UPF0435 family
HMCIFNEL_00725 4.4e-206 ydiM EGP Major facilitator Superfamily
HMCIFNEL_00726 2.6e-86 yfkM 1.11.1.6, 3.5.1.124 S protease
HMCIFNEL_00727 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMCIFNEL_00728 1.5e-123 yfkO C nitroreductase
HMCIFNEL_00729 1.8e-133 treR K transcriptional
HMCIFNEL_00730 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HMCIFNEL_00731 5.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMCIFNEL_00732 5.9e-113 yfkQ EG Spore germination protein
HMCIFNEL_00733 6e-67 yhdN S Domain of unknown function (DUF1992)
HMCIFNEL_00734 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMCIFNEL_00735 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HMCIFNEL_00736 1.2e-137 map 3.4.11.18 E Methionine aminopeptidase
HMCIFNEL_00737 1.2e-49 yflH S Protein of unknown function (DUF3243)
HMCIFNEL_00738 4.1e-19 yflI
HMCIFNEL_00739 8.9e-18 yflJ S Protein of unknown function (DUF2639)
HMCIFNEL_00740 1.1e-121 yflK S protein conserved in bacteria
HMCIFNEL_00741 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMCIFNEL_00742 3.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HMCIFNEL_00743 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HMCIFNEL_00744 8.5e-227 citM C Citrate transporter
HMCIFNEL_00745 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
HMCIFNEL_00746 1.3e-117 citT T response regulator
HMCIFNEL_00747 2e-286 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HMCIFNEL_00748 1.5e-199 yflS P Sodium:sulfate symporter transmembrane region
HMCIFNEL_00749 1.5e-21 yflS P Sodium:sulfate symporter transmembrane region
HMCIFNEL_00750 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HMCIFNEL_00751 7.6e-58 yflT S Heat induced stress protein YflT
HMCIFNEL_00752 2.9e-24 S Protein of unknown function (DUF3212)
HMCIFNEL_00753 3.3e-164 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HMCIFNEL_00754 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_00755 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_00756 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HMCIFNEL_00757 7.2e-189 yfmJ S N-terminal domain of oxidoreductase
HMCIFNEL_00758 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
HMCIFNEL_00759 2.2e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HMCIFNEL_00760 2.7e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMCIFNEL_00761 1.3e-72 L Integrase core domain
HMCIFNEL_00762 1.3e-19 iolT EGP Major facilitator Superfamily
HMCIFNEL_00763 1.3e-19 iolT EGP Major facilitator Superfamily
HMCIFNEL_00764 8.8e-81 S Protein of unknown function (DUF2690)
HMCIFNEL_00765 2.3e-20 yjfB S Putative motility protein
HMCIFNEL_00766 1.4e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
HMCIFNEL_00767 3.9e-44 T PhoQ Sensor
HMCIFNEL_00768 4.9e-102 yjgB S Domain of unknown function (DUF4309)
HMCIFNEL_00769 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HMCIFNEL_00770 8.3e-72 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HMCIFNEL_00771 1.6e-94 yjgD S Protein of unknown function (DUF1641)
HMCIFNEL_00774 3.9e-68 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HMCIFNEL_00776 8.9e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HMCIFNEL_00777 4.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HMCIFNEL_00778 8.2e-30
HMCIFNEL_00779 1.9e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HMCIFNEL_00780 2.8e-121 ybbM S transport system, permease component
HMCIFNEL_00781 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HMCIFNEL_00782 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
HMCIFNEL_00783 1.3e-90 yjlB S Cupin domain
HMCIFNEL_00784 1.2e-65 yjlC S Protein of unknown function (DUF1641)
HMCIFNEL_00785 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HMCIFNEL_00786 5.1e-278 uxaC 5.3.1.12 G glucuronate isomerase
HMCIFNEL_00787 3.7e-249 yjmB G symporter YjmB
HMCIFNEL_00788 2.5e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HMCIFNEL_00789 3.6e-188 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HMCIFNEL_00790 6.4e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HMCIFNEL_00791 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_00792 3.7e-227 exuT G Sugar (and other) transporter
HMCIFNEL_00793 6.4e-182 exuR K transcriptional
HMCIFNEL_00794 3.8e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HMCIFNEL_00795 3.8e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HMCIFNEL_00796 1.3e-129 MA20_18170 S membrane transporter protein
HMCIFNEL_00797 2.3e-78 yjoA S DinB family
HMCIFNEL_00798 3e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HMCIFNEL_00799 2.1e-213 S response regulator aspartate phosphatase
HMCIFNEL_00801 1.2e-39 S YCII-related domain
HMCIFNEL_00802 1.6e-158 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HMCIFNEL_00803 1.8e-60 yjqA S Bacterial PH domain
HMCIFNEL_00804 3.7e-108 yjqB S Pfam:DUF867
HMCIFNEL_00805 9.8e-160 ydbD P Catalase
HMCIFNEL_00806 1.6e-111 xkdA E IrrE N-terminal-like domain
HMCIFNEL_00807 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HMCIFNEL_00809 7.8e-157 xkdB K sequence-specific DNA binding
HMCIFNEL_00810 8.5e-109 xkdC L Bacterial dnaA protein
HMCIFNEL_00813 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HMCIFNEL_00814 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HMCIFNEL_00815 1.4e-139 xtmA L phage terminase small subunit
HMCIFNEL_00816 9.6e-255 xtmB S phage terminase, large subunit
HMCIFNEL_00817 5.4e-286 yqbA S portal protein
HMCIFNEL_00818 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HMCIFNEL_00819 5.8e-169 xkdG S Phage capsid family
HMCIFNEL_00820 5.6e-62 yqbG S Protein of unknown function (DUF3199)
HMCIFNEL_00821 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HMCIFNEL_00822 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HMCIFNEL_00823 9.3e-77 xkdJ
HMCIFNEL_00824 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HMCIFNEL_00825 6.1e-76 xkdM S Phage tail tube protein
HMCIFNEL_00826 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HMCIFNEL_00827 0.0 xkdO L Transglycosylase SLT domain
HMCIFNEL_00828 3.4e-115 xkdP S Lysin motif
HMCIFNEL_00829 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HMCIFNEL_00830 4.7e-39 xkdR S Protein of unknown function (DUF2577)
HMCIFNEL_00831 4.1e-69 xkdS S Protein of unknown function (DUF2634)
HMCIFNEL_00832 1.5e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HMCIFNEL_00833 2.4e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HMCIFNEL_00834 4.3e-40
HMCIFNEL_00835 5e-138
HMCIFNEL_00837 6e-11 S Phage uncharacterised protein (Phage_XkdX)
HMCIFNEL_00838 4.3e-35 xhlA S Haemolysin XhlA
HMCIFNEL_00839 9.3e-40 xhlB S SPP1 phage holin
HMCIFNEL_00840 5e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMCIFNEL_00841 6.7e-23 spoIISB S Stage II sporulation protein SB
HMCIFNEL_00842 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HMCIFNEL_00843 7.6e-175 pit P phosphate transporter
HMCIFNEL_00844 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HMCIFNEL_00845 1.2e-236 steT E amino acid
HMCIFNEL_00846 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HMCIFNEL_00847 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMCIFNEL_00848 3.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMCIFNEL_00850 3.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMCIFNEL_00851 2.6e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HMCIFNEL_00852 5.1e-153 dppA E D-aminopeptidase
HMCIFNEL_00853 4.5e-155 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCIFNEL_00854 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCIFNEL_00855 3.9e-187 dppD P Belongs to the ABC transporter superfamily
HMCIFNEL_00856 0.0 dppE E ABC transporter substrate-binding protein
HMCIFNEL_00858 5.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HMCIFNEL_00859 1.4e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HMCIFNEL_00860 2.7e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HMCIFNEL_00861 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
HMCIFNEL_00862 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HMCIFNEL_00863 1.7e-159 ykgA E Amidinotransferase
HMCIFNEL_00864 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HMCIFNEL_00865 2.4e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HMCIFNEL_00866 2.6e-08
HMCIFNEL_00867 2.3e-128 ykjA S Protein of unknown function (DUF421)
HMCIFNEL_00868 5.1e-98 ykkA S Protein of unknown function (DUF664)
HMCIFNEL_00869 2.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMCIFNEL_00870 1.3e-54 ykkC P Multidrug resistance protein
HMCIFNEL_00871 9.1e-50 ykkD P Multidrug resistance protein
HMCIFNEL_00872 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HMCIFNEL_00873 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMCIFNEL_00874 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMCIFNEL_00876 4.8e-70 ohrA O Organic hydroperoxide resistance protein
HMCIFNEL_00877 3.9e-75 ohrR K COG1846 Transcriptional regulators
HMCIFNEL_00878 2.4e-71 ohrB O Organic hydroperoxide resistance protein
HMCIFNEL_00879 6.2e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HMCIFNEL_00880 3e-95 L Transposase
HMCIFNEL_00881 3.3e-41 araB 2.7.1.16 C Belongs to the ribulokinase family
HMCIFNEL_00882 5.1e-08 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HMCIFNEL_00883 1.7e-31 yeaC S COG0714 MoxR-like ATPases
HMCIFNEL_00884 1.7e-12 tlpC 2.7.13.3 NT chemotaxis protein
HMCIFNEL_00886 5e-238 M nucleic acid phosphodiester bond hydrolysis
HMCIFNEL_00887 1e-29
HMCIFNEL_00888 3.5e-28
HMCIFNEL_00889 2.3e-18
HMCIFNEL_00891 3.9e-210 yjcL S Protein of unknown function (DUF819)
HMCIFNEL_00892 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
HMCIFNEL_00893 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMCIFNEL_00894 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMCIFNEL_00895 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
HMCIFNEL_00896 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HMCIFNEL_00897 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMCIFNEL_00898 1.7e-38
HMCIFNEL_00899 0.0 yjcD 3.6.4.12 L DNA helicase
HMCIFNEL_00900 2.9e-38 spoVIF S Stage VI sporulation protein F
HMCIFNEL_00903 4.3e-56 yjcA S Protein of unknown function (DUF1360)
HMCIFNEL_00904 2.3e-55 cotV S Spore Coat Protein X and V domain
HMCIFNEL_00905 2.1e-30 cotW
HMCIFNEL_00906 6.4e-77 cotX S Spore Coat Protein X and V domain
HMCIFNEL_00907 3.4e-96 cotY S Spore coat protein Z
HMCIFNEL_00908 5.2e-83 cotZ S Spore coat protein
HMCIFNEL_00909 5.9e-54 yjbX S Spore coat protein
HMCIFNEL_00910 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HMCIFNEL_00911 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMCIFNEL_00912 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HMCIFNEL_00913 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HMCIFNEL_00914 6.7e-30 thiS H thiamine diphosphate biosynthetic process
HMCIFNEL_00915 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
HMCIFNEL_00916 4.9e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HMCIFNEL_00917 6.4e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HMCIFNEL_00918 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMCIFNEL_00919 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HMCIFNEL_00920 2.6e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMCIFNEL_00921 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMCIFNEL_00922 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HMCIFNEL_00923 7.1e-62 yjbL S Belongs to the UPF0738 family
HMCIFNEL_00924 4.1e-101 yjbK S protein conserved in bacteria
HMCIFNEL_00925 8.2e-86 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HMCIFNEL_00926 3.7e-72 yjbI S Bacterial-like globin
HMCIFNEL_00927 4.7e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HMCIFNEL_00928 1.8e-20
HMCIFNEL_00929 0.0 pepF E oligoendopeptidase F
HMCIFNEL_00930 2e-219 yjbF S Competence protein
HMCIFNEL_00931 1.2e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HMCIFNEL_00932 6e-112 yjbE P Integral membrane protein TerC family
HMCIFNEL_00933 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMCIFNEL_00934 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMCIFNEL_00935 1.2e-203 yjbB EGP Major Facilitator Superfamily
HMCIFNEL_00936 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HMCIFNEL_00937 3.4e-197 oppD P Belongs to the ABC transporter superfamily
HMCIFNEL_00938 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCIFNEL_00939 3e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCIFNEL_00940 6.8e-311 oppA E ABC transporter substrate-binding protein
HMCIFNEL_00941 6.8e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HMCIFNEL_00942 5e-147 yjbA S Belongs to the UPF0736 family
HMCIFNEL_00943 1.8e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCIFNEL_00944 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCIFNEL_00945 1.4e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HMCIFNEL_00946 2.7e-185 appF E Belongs to the ABC transporter superfamily
HMCIFNEL_00947 1.8e-184 appD P Belongs to the ABC transporter superfamily
HMCIFNEL_00948 2.8e-148 yjaZ O Zn-dependent protease
HMCIFNEL_00949 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMCIFNEL_00950 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMCIFNEL_00951 2.7e-22 yjzB
HMCIFNEL_00952 7.3e-26 comZ S ComZ
HMCIFNEL_00953 2.5e-183 med S Transcriptional activator protein med
HMCIFNEL_00954 2.2e-99 yjaV
HMCIFNEL_00955 1.1e-141 yjaU I carboxylic ester hydrolase activity
HMCIFNEL_00956 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HMCIFNEL_00957 9.5e-28 yjzC S YjzC-like protein
HMCIFNEL_00958 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMCIFNEL_00959 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HMCIFNEL_00960 1.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMCIFNEL_00961 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HMCIFNEL_00962 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HMCIFNEL_00963 1e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMCIFNEL_00964 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMCIFNEL_00965 1.7e-88 norB G Major Facilitator Superfamily
HMCIFNEL_00966 2.9e-268 yitY C D-arabinono-1,4-lactone oxidase
HMCIFNEL_00967 1.5e-22 pilT S Proteolipid membrane potential modulator
HMCIFNEL_00968 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HMCIFNEL_00969 2.9e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HMCIFNEL_00970 4.6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HMCIFNEL_00972 1.2e-17 S Protein of unknown function (DUF3813)
HMCIFNEL_00973 5e-73 ipi S Intracellular proteinase inhibitor
HMCIFNEL_00974 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HMCIFNEL_00975 7.9e-157 yitS S protein conserved in bacteria
HMCIFNEL_00976 1.1e-308 nprB 3.4.24.28 E Peptidase M4
HMCIFNEL_00977 1.4e-44 yitR S Domain of unknown function (DUF3784)
HMCIFNEL_00978 2.9e-94
HMCIFNEL_00979 1.5e-58 K Transcriptional regulator PadR-like family
HMCIFNEL_00980 3.4e-97 S Sporulation delaying protein SdpA
HMCIFNEL_00981 3.4e-169
HMCIFNEL_00982 8.5e-94
HMCIFNEL_00983 4.5e-160 cvfB S protein conserved in bacteria
HMCIFNEL_00984 3.3e-54 yajQ S Belongs to the UPF0234 family
HMCIFNEL_00985 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HMCIFNEL_00986 1e-70 yjcF S Acetyltransferase (GNAT) domain
HMCIFNEL_00987 1.8e-156 yitH K Acetyltransferase (GNAT) domain
HMCIFNEL_00988 6.1e-143 yitG EGP Major facilitator Superfamily
HMCIFNEL_00989 3.8e-76 yitG EGP Major facilitator Superfamily
HMCIFNEL_00990 1.7e-37 gcd 1.1.5.2 G Glucose dehydrogenase
HMCIFNEL_00991 1.3e-32 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HMCIFNEL_00992 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMCIFNEL_00993 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMCIFNEL_00994 1.8e-37 yaaB S Domain of unknown function (DUF370)
HMCIFNEL_00995 9.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMCIFNEL_00996 2.4e-33 yaaA S S4 domain
HMCIFNEL_00997 1.1e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMCIFNEL_00998 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMCIFNEL_00999 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMCIFNEL_01000 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMCIFNEL_01001 3.2e-107 jag S single-stranded nucleic acid binding R3H
HMCIFNEL_01002 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMCIFNEL_01003 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMCIFNEL_01004 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HMCIFNEL_01005 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HMCIFNEL_01006 4.1e-72 S Bacterial PH domain
HMCIFNEL_01007 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HMCIFNEL_01008 2.1e-149 spo0J K Belongs to the ParB family
HMCIFNEL_01009 1.6e-111 yyaC S Sporulation protein YyaC
HMCIFNEL_01010 8.1e-177 yyaD S Membrane
HMCIFNEL_01011 2.3e-33 yyzM S protein conserved in bacteria
HMCIFNEL_01012 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMCIFNEL_01013 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMCIFNEL_01014 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HMCIFNEL_01015 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMCIFNEL_01016 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMCIFNEL_01017 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HMCIFNEL_01018 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HMCIFNEL_01019 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCIFNEL_01020 9.3e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HMCIFNEL_01021 1.1e-242 EGP Major facilitator superfamily
HMCIFNEL_01022 8e-168 yyaK S CAAX protease self-immunity
HMCIFNEL_01023 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HMCIFNEL_01024 1.1e-243 tetL EGP Major facilitator Superfamily
HMCIFNEL_01025 6.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
HMCIFNEL_01026 1e-65 yyaQ S YjbR
HMCIFNEL_01027 2.1e-91 yyaR K Acetyltransferase (GNAT) domain
HMCIFNEL_01028 2.7e-95 yyaS S Membrane
HMCIFNEL_01029 4.2e-69 yjcF S Acetyltransferase (GNAT) domain
HMCIFNEL_01030 2.8e-76 yybA 2.3.1.57 K transcriptional
HMCIFNEL_01031 5.7e-78 S Metallo-beta-lactamase superfamily
HMCIFNEL_01032 1.1e-101 ynfM EGP Major facilitator Superfamily
HMCIFNEL_01033 6.9e-121 yybG S Pentapeptide repeat-containing protein
HMCIFNEL_01034 8.6e-66 yybH S SnoaL-like domain
HMCIFNEL_01035 2.2e-121
HMCIFNEL_01036 3.7e-110 K TipAS antibiotic-recognition domain
HMCIFNEL_01037 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HMCIFNEL_01039 3.2e-27
HMCIFNEL_01040 2.3e-33
HMCIFNEL_01041 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HMCIFNEL_01042 1.7e-66 ydeP3 K Transcriptional regulator
HMCIFNEL_01043 4e-14 cotF M Spore coat protein
HMCIFNEL_01045 8.3e-160 yybS S membrane
HMCIFNEL_01046 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMCIFNEL_01047 1.9e-72 rplI J binds to the 23S rRNA
HMCIFNEL_01048 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMCIFNEL_01049 2.7e-219 yeaN P COG2807 Cyanate permease
HMCIFNEL_01050 1.9e-15 yycC K YycC-like protein
HMCIFNEL_01052 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HMCIFNEL_01053 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMCIFNEL_01054 1.6e-54 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCIFNEL_01055 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMCIFNEL_01060 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_01061 0.0 vicK 2.7.13.3 T Histidine kinase
HMCIFNEL_01062 2.6e-258 yycH S protein conserved in bacteria
HMCIFNEL_01063 6.2e-154 yycI S protein conserved in bacteria
HMCIFNEL_01064 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HMCIFNEL_01065 1.4e-215 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMCIFNEL_01066 3.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HMCIFNEL_01067 7.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HMCIFNEL_01068 2.8e-260 rocE E amino acid
HMCIFNEL_01069 2e-166 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HMCIFNEL_01071 1.5e-187 S aspartate phosphatase
HMCIFNEL_01072 1.2e-82 yycN 2.3.1.128 K Acetyltransferase
HMCIFNEL_01073 9.3e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HMCIFNEL_01074 9.6e-206 yycP
HMCIFNEL_01075 3.3e-20 yycQ S Protein of unknown function (DUF2651)
HMCIFNEL_01077 3.7e-232 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HMCIFNEL_01078 3.5e-27
HMCIFNEL_01079 1.1e-09 S YyzF-like protein
HMCIFNEL_01080 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMCIFNEL_01081 4.1e-167
HMCIFNEL_01082 8.1e-235 T Putative serine esterase (DUF676)
HMCIFNEL_01083 3.6e-08
HMCIFNEL_01084 7.4e-283 L ATPase involved in DNA repair
HMCIFNEL_01085 9.9e-57 basS 2.7.13.3 T Sensor protein basS
HMCIFNEL_01086 4.1e-40 S RelE family toxin-antitoxin system
HMCIFNEL_01087 2.1e-75 L Belongs to the 'phage' integrase family
HMCIFNEL_01088 9.6e-11
HMCIFNEL_01089 3.4e-33 K Helix-turn-helix XRE-family like proteins
HMCIFNEL_01090 4.3e-40
HMCIFNEL_01091 5.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HMCIFNEL_01093 8.7e-30 cspL K Cold shock
HMCIFNEL_01094 3e-78 carD K Transcription factor
HMCIFNEL_01095 4.6e-35 ydzE EG spore germination
HMCIFNEL_01096 3.2e-161 rhaS5 K AraC-like ligand binding domain
HMCIFNEL_01097 6.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMCIFNEL_01098 8.4e-162 ydeE K AraC family transcriptional regulator
HMCIFNEL_01099 1.5e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCIFNEL_01100 2.3e-154 ydeG EGP Major facilitator superfamily
HMCIFNEL_01101 6.6e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HMCIFNEL_01102 4e-108
HMCIFNEL_01103 3.2e-09 S SNARE associated Golgi protein
HMCIFNEL_01104 1.8e-14 ptsH G PTS HPr component phosphorylation site
HMCIFNEL_01105 8.8e-85 K Transcriptional regulator C-terminal region
HMCIFNEL_01106 1.6e-152 ydeK EG -transporter
HMCIFNEL_01107 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCIFNEL_01108 2.3e-72 maoC I N-terminal half of MaoC dehydratase
HMCIFNEL_01109 1.6e-105 ydeN S Serine hydrolase
HMCIFNEL_01110 3e-56 K HxlR-like helix-turn-helix
HMCIFNEL_01111 1.2e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HMCIFNEL_01112 8.2e-57 arsR K transcriptional
HMCIFNEL_01113 1.4e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HMCIFNEL_01114 3.5e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HMCIFNEL_01115 1.8e-144 ydfB J GNAT acetyltransferase
HMCIFNEL_01116 2e-158 ydfC EG EamA-like transporter family
HMCIFNEL_01117 6.2e-271 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCIFNEL_01118 7.2e-115 ydfE S Flavin reductase like domain
HMCIFNEL_01119 1.7e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HMCIFNEL_01120 2.9e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HMCIFNEL_01122 3.2e-177 ydfH 2.7.13.3 T Histidine kinase
HMCIFNEL_01123 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMCIFNEL_01124 0.0 ydfJ S drug exporters of the RND superfamily
HMCIFNEL_01125 5.5e-116 S Protein of unknown function (DUF554)
HMCIFNEL_01126 6.6e-145 K Bacterial transcription activator, effector binding domain
HMCIFNEL_01128 5.6e-11 S response regulator aspartate phosphatase
HMCIFNEL_01129 5.4e-13
HMCIFNEL_01132 1.5e-57 L COG3666 Transposase and inactivated derivatives
HMCIFNEL_01133 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMCIFNEL_01134 8.4e-108 ydfN C nitroreductase
HMCIFNEL_01135 1.7e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HMCIFNEL_01136 8.8e-63 mhqP S DoxX
HMCIFNEL_01137 1.6e-55 traF CO Thioredoxin
HMCIFNEL_01138 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HMCIFNEL_01139 6.3e-29
HMCIFNEL_01141 1.3e-25 ydfR S Protein of unknown function (DUF421)
HMCIFNEL_01142 5.1e-28 ydfR S Protein of unknown function (DUF421)
HMCIFNEL_01143 1.5e-121 ydfS S Protein of unknown function (DUF421)
HMCIFNEL_01144 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
HMCIFNEL_01145 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
HMCIFNEL_01146 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HMCIFNEL_01147 2e-98 K Bacterial regulatory proteins, tetR family
HMCIFNEL_01148 3.4e-50 S DoxX-like family
HMCIFNEL_01149 1.7e-84 yycN 2.3.1.128 K Acetyltransferase
HMCIFNEL_01150 1.8e-190 expZ S ABC transporter
HMCIFNEL_01151 1.1e-98 expZ S ABC transporter
HMCIFNEL_01152 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HMCIFNEL_01153 2.5e-89 dinB S DinB family
HMCIFNEL_01154 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HMCIFNEL_01155 0.0 ydgH S drug exporters of the RND superfamily
HMCIFNEL_01156 2.3e-113 drgA C nitroreductase
HMCIFNEL_01157 7.1e-69 ydgJ K Winged helix DNA-binding domain
HMCIFNEL_01158 1.6e-208 tcaB EGP Major facilitator Superfamily
HMCIFNEL_01159 1.6e-121 ydhB S membrane transporter protein
HMCIFNEL_01160 6.5e-122 ydhC K FCD
HMCIFNEL_01161 2e-241 ydhD M Glycosyl hydrolase
HMCIFNEL_01162 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HMCIFNEL_01163 1.3e-125
HMCIFNEL_01164 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HMCIFNEL_01165 4.3e-67 frataxin S Domain of unknown function (DU1801)
HMCIFNEL_01167 8.6e-84 K Acetyltransferase (GNAT) domain
HMCIFNEL_01168 7.6e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMCIFNEL_01169 9.4e-98 ydhK M Protein of unknown function (DUF1541)
HMCIFNEL_01170 4.6e-200 pbuE EGP Major facilitator Superfamily
HMCIFNEL_01171 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HMCIFNEL_01172 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HMCIFNEL_01173 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCIFNEL_01174 8.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMCIFNEL_01175 1.1e-132 ydhQ K UTRA
HMCIFNEL_01176 7.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HMCIFNEL_01177 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMCIFNEL_01178 2.2e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HMCIFNEL_01179 4.6e-157 ydhU P Catalase
HMCIFNEL_01182 2.8e-33 tatB U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation
HMCIFNEL_01185 2.1e-36 mreB D Rod shape-determining protein MreB
HMCIFNEL_01186 4.4e-18 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HMCIFNEL_01187 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HMCIFNEL_01188 1e-210 yttB EGP Major facilitator Superfamily
HMCIFNEL_01189 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HMCIFNEL_01190 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HMCIFNEL_01191 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMCIFNEL_01192 2.1e-51 ytwF P Sulfurtransferase
HMCIFNEL_01193 3.4e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HMCIFNEL_01194 4.4e-144 amyC P ABC transporter (permease)
HMCIFNEL_01195 6.2e-168 amyD P ABC transporter
HMCIFNEL_01196 7.3e-247 msmE G Bacterial extracellular solute-binding protein
HMCIFNEL_01197 1.8e-187 msmR K Transcriptional regulator
HMCIFNEL_01198 1.9e-172 ytaP S Acetyl xylan esterase (AXE1)
HMCIFNEL_01199 2.9e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HMCIFNEL_01200 5.1e-251 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HMCIFNEL_01201 4.3e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HMCIFNEL_01202 3.8e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HMCIFNEL_01203 6.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HMCIFNEL_01204 2.4e-220 bioI 1.14.14.46 C Cytochrome P450
HMCIFNEL_01205 6.2e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HMCIFNEL_01206 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HMCIFNEL_01207 9.3e-286 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HMCIFNEL_01208 3.3e-135 ytdP K Transcriptional regulator
HMCIFNEL_01209 9.5e-278 ytdP K Transcriptional regulator
HMCIFNEL_01210 5e-65 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HMCIFNEL_01211 4.2e-95 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HMCIFNEL_01212 2.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HMCIFNEL_01213 5.6e-71 yteS G transport
HMCIFNEL_01214 2.4e-189 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HMCIFNEL_01215 7e-76 yteU S Integral membrane protein
HMCIFNEL_01216 3.1e-26 yteV S Sporulation protein Cse60
HMCIFNEL_01217 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HMCIFNEL_01218 9e-231 ytfP S HI0933-like protein
HMCIFNEL_01219 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMCIFNEL_01220 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMCIFNEL_01221 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HMCIFNEL_01222 4.8e-131 ythP V ABC transporter
HMCIFNEL_01223 4.9e-202 ythQ U Bacterial ABC transporter protein EcsB
HMCIFNEL_01224 2.1e-225 pbuO S permease
HMCIFNEL_01225 3.9e-270 pepV 3.5.1.18 E Dipeptidase
HMCIFNEL_01226 1.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMCIFNEL_01227 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HMCIFNEL_01228 2.2e-165 ytlQ
HMCIFNEL_01229 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMCIFNEL_01230 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HMCIFNEL_01231 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HMCIFNEL_01232 2e-45 ytzH S YtzH-like protein
HMCIFNEL_01233 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMCIFNEL_01234 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HMCIFNEL_01235 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HMCIFNEL_01236 2.2e-51 ytzB S small secreted protein
HMCIFNEL_01237 1.9e-116 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HMCIFNEL_01238 2.3e-78 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HMCIFNEL_01239 3.5e-21 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HMCIFNEL_01240 6.7e-48 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HMCIFNEL_01241 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMCIFNEL_01242 4.8e-148 ytpQ S Belongs to the UPF0354 family
HMCIFNEL_01243 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMCIFNEL_01244 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HMCIFNEL_01245 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMCIFNEL_01246 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMCIFNEL_01247 6.6e-17 ytxH S COG4980 Gas vesicle protein
HMCIFNEL_01248 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
HMCIFNEL_01249 1.1e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HMCIFNEL_01250 3.8e-182 ccpA K catabolite control protein A
HMCIFNEL_01251 2.1e-146 motA N flagellar motor
HMCIFNEL_01252 5.2e-125 motS N Flagellar motor protein
HMCIFNEL_01253 5.4e-225 acuC BQ histone deacetylase
HMCIFNEL_01254 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HMCIFNEL_01255 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HMCIFNEL_01256 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HMCIFNEL_01257 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMCIFNEL_01259 1.3e-72 L Integrase core domain
HMCIFNEL_01260 5.7e-15 pre D plasmid recombination enzyme
HMCIFNEL_01261 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HMCIFNEL_01262 1.6e-236 ktrB P Potassium
HMCIFNEL_01263 1e-38 yiaA S yiaA/B two helix domain
HMCIFNEL_01264 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMCIFNEL_01265 2.7e-272 yubD P Major Facilitator Superfamily
HMCIFNEL_01266 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HMCIFNEL_01268 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMCIFNEL_01269 1.3e-194 yubA S transporter activity
HMCIFNEL_01270 9.7e-183 ygjR S Oxidoreductase
HMCIFNEL_01271 2.6e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HMCIFNEL_01272 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HMCIFNEL_01273 2.5e-272 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HMCIFNEL_01274 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HMCIFNEL_01275 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HMCIFNEL_01276 7.3e-238 mcpA NT chemotaxis protein
HMCIFNEL_01277 1e-292 mcpA NT chemotaxis protein
HMCIFNEL_01278 1.6e-211 mcpA NT chemotaxis protein
HMCIFNEL_01279 1.5e-222 mcpA NT chemotaxis protein
HMCIFNEL_01280 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HMCIFNEL_01281 1e-35
HMCIFNEL_01282 2.1e-72 yugU S Uncharacterised protein family UPF0047
HMCIFNEL_01283 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HMCIFNEL_01284 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HMCIFNEL_01285 1.4e-116 yugP S Zn-dependent protease
HMCIFNEL_01286 3.7e-36
HMCIFNEL_01287 1.2e-52 mstX S Membrane-integrating protein Mistic
HMCIFNEL_01288 8.2e-182 yugO P COG1226 Kef-type K transport systems
HMCIFNEL_01289 1.4e-71 yugN S YugN-like family
HMCIFNEL_01291 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HMCIFNEL_01292 1.4e-228 yugK C Dehydrogenase
HMCIFNEL_01293 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HMCIFNEL_01294 1.1e-34 yuzA S Domain of unknown function (DUF378)
HMCIFNEL_01295 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HMCIFNEL_01296 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HMCIFNEL_01297 1.6e-85 alaR K Transcriptional regulator
HMCIFNEL_01298 4.9e-156 yugF I Hydrolase
HMCIFNEL_01299 4.6e-39 yugE S Domain of unknown function (DUF1871)
HMCIFNEL_01300 1.7e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HMCIFNEL_01301 1.7e-232 T PhoQ Sensor
HMCIFNEL_01302 4.1e-68 kapB G Kinase associated protein B
HMCIFNEL_01303 2.7e-114 kapD L the KinA pathway to sporulation
HMCIFNEL_01305 1.1e-184 yuxJ EGP Major facilitator Superfamily
HMCIFNEL_01306 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HMCIFNEL_01307 1.8e-74 yuxK S protein conserved in bacteria
HMCIFNEL_01308 1.8e-77 yufK S Family of unknown function (DUF5366)
HMCIFNEL_01309 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HMCIFNEL_01310 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HMCIFNEL_01311 1.7e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HMCIFNEL_01312 2.7e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HMCIFNEL_01313 4.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HMCIFNEL_01314 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMCIFNEL_01315 1.3e-233 maeN C COG3493 Na citrate symporter
HMCIFNEL_01316 5e-15
HMCIFNEL_01317 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HMCIFNEL_01318 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMCIFNEL_01319 3.4e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMCIFNEL_01320 3.9e-260 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMCIFNEL_01321 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMCIFNEL_01322 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMCIFNEL_01323 3.3e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HMCIFNEL_01324 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HMCIFNEL_01325 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMCIFNEL_01326 5.4e-311 comP 2.7.13.3 T Histidine kinase
HMCIFNEL_01327 3.8e-53 bamA M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HMCIFNEL_01328 3.2e-13 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HMCIFNEL_01333 2e-08
HMCIFNEL_01340 1.3e-09
HMCIFNEL_01341 7.8e-08
HMCIFNEL_01350 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMCIFNEL_01351 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMCIFNEL_01352 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HMCIFNEL_01353 2.9e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMCIFNEL_01354 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMCIFNEL_01355 9.9e-77 tspO T membrane
HMCIFNEL_01356 8.2e-204 cotI S Spore coat protein
HMCIFNEL_01357 3.4e-216 cotSA M Glycosyl transferases group 1
HMCIFNEL_01358 1.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
HMCIFNEL_01360 1.8e-226 ytcC M Glycosyltransferase Family 4
HMCIFNEL_01361 2.2e-176 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HMCIFNEL_01362 5.8e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMCIFNEL_01363 7.4e-152 galU 2.7.7.9 M Nucleotidyl transferase
HMCIFNEL_01364 9.7e-132 dksA T COG1734 DnaK suppressor protein
HMCIFNEL_01365 1.1e-269 menF 5.4.4.2 HQ Isochorismate synthase
HMCIFNEL_01366 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HMCIFNEL_01367 1.7e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HMCIFNEL_01368 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HMCIFNEL_01369 2.4e-270 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HMCIFNEL_01370 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HMCIFNEL_01371 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
HMCIFNEL_01372 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HMCIFNEL_01373 1.8e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HMCIFNEL_01374 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HMCIFNEL_01375 4.3e-24 S Domain of Unknown Function (DUF1540)
HMCIFNEL_01376 5.2e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HMCIFNEL_01377 6.8e-248 cydA 1.10.3.14 C oxidase, subunit
HMCIFNEL_01378 6.1e-41 rpmE2 J Ribosomal protein L31
HMCIFNEL_01379 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HMCIFNEL_01380 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMCIFNEL_01381 1.1e-72 ytkA S YtkA-like
HMCIFNEL_01383 2.1e-76 dps P Belongs to the Dps family
HMCIFNEL_01384 1.7e-61 ytkC S Bacteriophage holin family
HMCIFNEL_01385 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HMCIFNEL_01386 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HMCIFNEL_01387 1.4e-144 ytlC P ABC transporter
HMCIFNEL_01388 2.8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HMCIFNEL_01389 1.1e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HMCIFNEL_01390 4.7e-38 ytmB S Protein of unknown function (DUF2584)
HMCIFNEL_01391 2.8e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HMCIFNEL_01392 1.4e-223 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMCIFNEL_01393 0.0 asnB 6.3.5.4 E Asparagine synthase
HMCIFNEL_01394 1.7e-254 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HMCIFNEL_01395 2.7e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HMCIFNEL_01396 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HMCIFNEL_01397 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HMCIFNEL_01398 7.4e-106 ytqB J Putative rRNA methylase
HMCIFNEL_01399 8.1e-190 yhcC S Fe-S oxidoreductase
HMCIFNEL_01400 1.5e-40 ytzC S Protein of unknown function (DUF2524)
HMCIFNEL_01402 5.1e-66 ytrA K GntR family transcriptional regulator
HMCIFNEL_01403 4.2e-161 ytrB P abc transporter atp-binding protein
HMCIFNEL_01404 2.1e-07 P ABC-2 family transporter protein
HMCIFNEL_01405 1.2e-116 P ABC-2 family transporter protein
HMCIFNEL_01406 1.7e-147
HMCIFNEL_01407 9.1e-127 ytrE V ABC transporter, ATP-binding protein
HMCIFNEL_01408 1.9e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HMCIFNEL_01409 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_01410 4.9e-182 T PhoQ Sensor
HMCIFNEL_01411 5.6e-138 bceA V ABC transporter, ATP-binding protein
HMCIFNEL_01412 2.5e-311 bceB V ABC transporter (permease)
HMCIFNEL_01413 2.1e-38 repA S RePlication protein
HMCIFNEL_01414 7.9e-108 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HMCIFNEL_01415 9.4e-113 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HMCIFNEL_01416 3.6e-21 ywtC
HMCIFNEL_01417 9.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HMCIFNEL_01418 8.6e-70 pgsC S biosynthesis protein
HMCIFNEL_01419 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HMCIFNEL_01420 5.5e-178 rbsR K transcriptional
HMCIFNEL_01421 2.5e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMCIFNEL_01422 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMCIFNEL_01423 4e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HMCIFNEL_01424 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HMCIFNEL_01425 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HMCIFNEL_01426 1.2e-91 batE T Sh3 type 3 domain protein
HMCIFNEL_01427 8e-48 ywsA S Protein of unknown function (DUF3892)
HMCIFNEL_01428 6.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HMCIFNEL_01429 1.4e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HMCIFNEL_01430 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMCIFNEL_01431 1.1e-169 alsR K LysR substrate binding domain
HMCIFNEL_01432 2.4e-179 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HMCIFNEL_01433 1.4e-124 ywrJ
HMCIFNEL_01434 8.8e-77 cotB
HMCIFNEL_01435 1.4e-23 cotB
HMCIFNEL_01436 2.4e-206 cotH M Spore Coat
HMCIFNEL_01437 1.1e-12
HMCIFNEL_01438 9.9e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HMCIFNEL_01439 2.7e-52 S Domain of unknown function (DUF4181)
HMCIFNEL_01440 1.1e-300 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HMCIFNEL_01441 8e-82 ywrC K Transcriptional regulator
HMCIFNEL_01442 1.2e-103 ywrB P Chromate transporter
HMCIFNEL_01443 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
HMCIFNEL_01445 1.1e-100 ywqN S NAD(P)H-dependent
HMCIFNEL_01446 1.4e-161 K Transcriptional regulator
HMCIFNEL_01447 3e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HMCIFNEL_01448 3.9e-25
HMCIFNEL_01449 1.6e-81 ywqJ S Pre-toxin TG
HMCIFNEL_01450 5.2e-17
HMCIFNEL_01451 7.9e-43
HMCIFNEL_01452 3.3e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
HMCIFNEL_01453 1.2e-37 ywqI S Family of unknown function (DUF5344)
HMCIFNEL_01454 1.3e-19 S Domain of unknown function (DUF5082)
HMCIFNEL_01455 5.4e-152 ywqG S Domain of unknown function (DUF1963)
HMCIFNEL_01456 1.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMCIFNEL_01457 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HMCIFNEL_01458 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HMCIFNEL_01459 5.9e-116 ywqC M biosynthesis protein
HMCIFNEL_01460 1.2e-17
HMCIFNEL_01461 7.8e-307 ywqB S SWIM zinc finger
HMCIFNEL_01462 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HMCIFNEL_01463 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HMCIFNEL_01464 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HMCIFNEL_01465 9.8e-58 ssbB L Single-stranded DNA-binding protein
HMCIFNEL_01466 1.2e-29 ywpG
HMCIFNEL_01467 6.9e-66 ywpF S YwpF-like protein
HMCIFNEL_01468 2.6e-49 srtA 3.4.22.70 M Sortase family
HMCIFNEL_01469 1.2e-152 ywpD T Histidine kinase
HMCIFNEL_01470 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMCIFNEL_01471 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMCIFNEL_01472 2.3e-198 S aspartate phosphatase
HMCIFNEL_01473 2.6e-141 flhP N flagellar basal body
HMCIFNEL_01474 6.9e-126 flhO N flagellar basal body
HMCIFNEL_01475 3.5e-180 mbl D Rod shape-determining protein
HMCIFNEL_01476 3e-44 spoIIID K Stage III sporulation protein D
HMCIFNEL_01477 4.7e-70 ywoH K COG1846 Transcriptional regulators
HMCIFNEL_01478 4.6e-211 ywoG EGP Major facilitator Superfamily
HMCIFNEL_01479 1.5e-224 ywoF P Right handed beta helix region
HMCIFNEL_01480 9.8e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HMCIFNEL_01481 1.6e-239 ywoD EGP Major facilitator superfamily
HMCIFNEL_01482 1.2e-103 phzA Q Isochorismatase family
HMCIFNEL_01483 2.2e-76
HMCIFNEL_01484 2.5e-225 amt P Ammonium transporter
HMCIFNEL_01485 1.6e-58 nrgB K Belongs to the P(II) protein family
HMCIFNEL_01486 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HMCIFNEL_01487 2.3e-72 ywnJ S VanZ like family
HMCIFNEL_01488 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HMCIFNEL_01489 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HMCIFNEL_01490 1.4e-07 ywnC S Family of unknown function (DUF5362)
HMCIFNEL_01491 3.2e-69 ywnF S Family of unknown function (DUF5392)
HMCIFNEL_01492 2.7e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMCIFNEL_01493 5.9e-143 mta K transcriptional
HMCIFNEL_01494 1.7e-58 ywnC S Family of unknown function (DUF5362)
HMCIFNEL_01495 4.2e-110 ywnB S NAD(P)H-binding
HMCIFNEL_01496 1.7e-64 ywnA K Transcriptional regulator
HMCIFNEL_01497 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HMCIFNEL_01498 1.6e-61 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HMCIFNEL_01499 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HMCIFNEL_01500 4.4e-113 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HMCIFNEL_01501 1.4e-120 urtD S ATPases associated with a variety of cellular activities
HMCIFNEL_01502 3.6e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
HMCIFNEL_01503 4.6e-147 urtB E Belongs to the binding-protein-dependent transport system permease family
HMCIFNEL_01504 8.8e-221 urtA E Receptor family ligand binding region
HMCIFNEL_01505 3.6e-09 csbD K CsbD-like
HMCIFNEL_01506 5.1e-84 ywmF S Peptidase M50
HMCIFNEL_01507 7.9e-104 S response regulator aspartate phosphatase
HMCIFNEL_01508 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMCIFNEL_01509 2.9e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HMCIFNEL_01511 2.7e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HMCIFNEL_01512 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HMCIFNEL_01513 9.8e-178 spoIID D Stage II sporulation protein D
HMCIFNEL_01514 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMCIFNEL_01515 3.4e-132 ywmB S TATA-box binding
HMCIFNEL_01516 1.3e-32 ywzB S membrane
HMCIFNEL_01517 4.8e-87 ywmA
HMCIFNEL_01518 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMCIFNEL_01519 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMCIFNEL_01520 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMCIFNEL_01521 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMCIFNEL_01522 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMCIFNEL_01523 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMCIFNEL_01524 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMCIFNEL_01525 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HMCIFNEL_01526 2.5e-62 atpI S ATP synthase
HMCIFNEL_01527 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMCIFNEL_01528 6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMCIFNEL_01529 1.6e-94 ywlG S Belongs to the UPF0340 family
HMCIFNEL_01530 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HMCIFNEL_01531 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMCIFNEL_01532 1.1e-90 mntP P Probably functions as a manganese efflux pump
HMCIFNEL_01533 2.2e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMCIFNEL_01534 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HMCIFNEL_01535 6.1e-112 spoIIR S stage II sporulation protein R
HMCIFNEL_01536 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
HMCIFNEL_01538 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMCIFNEL_01539 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMCIFNEL_01540 2.1e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCIFNEL_01541 5.1e-88 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HMCIFNEL_01542 8.6e-160 ywkB S Membrane transport protein
HMCIFNEL_01543 0.0 sfcA 1.1.1.38 C malic enzyme
HMCIFNEL_01544 1.6e-103 tdk 2.7.1.21 F thymidine kinase
HMCIFNEL_01545 1.1e-32 rpmE J Binds the 23S rRNA
HMCIFNEL_01546 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMCIFNEL_01547 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HMCIFNEL_01548 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMCIFNEL_01549 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMCIFNEL_01550 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HMCIFNEL_01551 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HMCIFNEL_01552 1.3e-90 ywjG S Domain of unknown function (DUF2529)
HMCIFNEL_01553 2.5e-11 tnpIS3 L Transposase
HMCIFNEL_01554 1.3e-42 L Integrase core domain
HMCIFNEL_01555 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMCIFNEL_01556 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMCIFNEL_01557 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HMCIFNEL_01558 0.0 fadF C COG0247 Fe-S oxidoreductase
HMCIFNEL_01559 3.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HMCIFNEL_01560 2.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HMCIFNEL_01561 2.7e-42 ywjC
HMCIFNEL_01562 5.9e-94 ywjB H RibD C-terminal domain
HMCIFNEL_01563 0.0 ywjA V ABC transporter
HMCIFNEL_01564 7.9e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMCIFNEL_01565 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
HMCIFNEL_01566 1.1e-93 narJ 1.7.5.1 C nitrate reductase
HMCIFNEL_01567 4.3e-296 narH 1.7.5.1 C Nitrate reductase, beta
HMCIFNEL_01568 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMCIFNEL_01569 7e-86 arfM T cyclic nucleotide binding
HMCIFNEL_01570 1.1e-138 ywiC S YwiC-like protein
HMCIFNEL_01571 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HMCIFNEL_01572 1e-213 narK P COG2223 Nitrate nitrite transporter
HMCIFNEL_01573 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMCIFNEL_01574 4.7e-73 ywiB S protein conserved in bacteria
HMCIFNEL_01575 1e-07 S Bacteriocin subtilosin A
HMCIFNEL_01576 4.9e-270 C Fe-S oxidoreductases
HMCIFNEL_01578 3.3e-132 cbiO V ABC transporter
HMCIFNEL_01579 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HMCIFNEL_01580 1.4e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
HMCIFNEL_01581 6.6e-248 L Peptidase, M16
HMCIFNEL_01583 6.3e-166 ywhL CO amine dehydrogenase activity
HMCIFNEL_01584 2.6e-55 ywhL CO amine dehydrogenase activity
HMCIFNEL_01585 4.5e-107 ywhK CO amine dehydrogenase activity
HMCIFNEL_01586 3.5e-79 ywhK CO amine dehydrogenase activity
HMCIFNEL_01587 1.2e-78 S aspartate phosphatase
HMCIFNEL_01589 7e-27 ywhH S Aminoacyl-tRNA editing domain
HMCIFNEL_01590 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HMCIFNEL_01591 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HMCIFNEL_01592 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMCIFNEL_01593 2e-94 ywhD S YwhD family
HMCIFNEL_01594 5.1e-119 ywhC S Peptidase family M50
HMCIFNEL_01595 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HMCIFNEL_01596 3.3e-71 ywhA K Transcriptional regulator
HMCIFNEL_01597 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMCIFNEL_01599 1.6e-234 mmr U Major Facilitator Superfamily
HMCIFNEL_01600 6.2e-79 yffB K Transcriptional regulator
HMCIFNEL_01601 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
HMCIFNEL_01602 2.5e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HMCIFNEL_01603 3.1e-36 ywzC S Belongs to the UPF0741 family
HMCIFNEL_01604 2.4e-107 rsfA_1
HMCIFNEL_01605 1.7e-154 ywfM EG EamA-like transporter family
HMCIFNEL_01606 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HMCIFNEL_01607 7.1e-156 cysL K Transcriptional regulator
HMCIFNEL_01608 6.2e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HMCIFNEL_01609 3.3e-146 ywfI C May function as heme-dependent peroxidase
HMCIFNEL_01610 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
HMCIFNEL_01611 2.3e-82 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HMCIFNEL_01612 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_01613 1.2e-120 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HMCIFNEL_01614 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HMCIFNEL_01615 4.3e-204 ywfA EGP Major facilitator Superfamily
HMCIFNEL_01616 5.7e-261 lysP E amino acid
HMCIFNEL_01617 0.0 rocB E arginine degradation protein
HMCIFNEL_01618 1.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HMCIFNEL_01619 6.9e-206 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMCIFNEL_01620 1.2e-77
HMCIFNEL_01621 1.3e-86 spsL 5.1.3.13 M Spore Coat
HMCIFNEL_01622 2.9e-69 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMCIFNEL_01623 6.6e-69 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMCIFNEL_01624 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMCIFNEL_01625 3e-136 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMCIFNEL_01626 2.3e-187 spsG M Spore Coat
HMCIFNEL_01627 1.3e-128 spsF M Spore Coat
HMCIFNEL_01628 2.1e-213 spsE 2.5.1.56 M acid synthase
HMCIFNEL_01629 3.7e-162 spsD 2.3.1.210 K Spore Coat
HMCIFNEL_01630 1.6e-221 spsC E Belongs to the DegT DnrJ EryC1 family
HMCIFNEL_01631 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
HMCIFNEL_01632 1.8e-144 spsA M Spore Coat
HMCIFNEL_01633 8.3e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HMCIFNEL_01634 1.6e-58 ywdK S small membrane protein
HMCIFNEL_01635 3.7e-238 ywdJ F Xanthine uracil
HMCIFNEL_01636 7.7e-49 ywdI S Family of unknown function (DUF5327)
HMCIFNEL_01637 5e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HMCIFNEL_01638 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMCIFNEL_01639 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HMCIFNEL_01641 7.5e-112 ywdD
HMCIFNEL_01642 6.3e-57 pex K Transcriptional regulator PadR-like family
HMCIFNEL_01643 3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMCIFNEL_01644 2e-28 ywdA
HMCIFNEL_01645 2.1e-287 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HMCIFNEL_01646 1.9e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMCIFNEL_01647 3.3e-138 focA P Formate/nitrite transporter
HMCIFNEL_01648 1e-148 sacT K transcriptional antiterminator
HMCIFNEL_01651 0.0 vpr O Belongs to the peptidase S8 family
HMCIFNEL_01652 1.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMCIFNEL_01653 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HMCIFNEL_01654 8.6e-202 rodA D Belongs to the SEDS family
HMCIFNEL_01655 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HMCIFNEL_01656 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HMCIFNEL_01657 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HMCIFNEL_01658 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMCIFNEL_01659 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HMCIFNEL_01660 1e-35 ywzA S membrane
HMCIFNEL_01661 3.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMCIFNEL_01662 4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMCIFNEL_01663 9.5e-60 gtcA S GtrA-like protein
HMCIFNEL_01664 3.9e-119 ywcC K transcriptional regulator
HMCIFNEL_01666 9.8e-49 ywcB S Protein of unknown function, DUF485
HMCIFNEL_01667 1.5e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMCIFNEL_01668 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HMCIFNEL_01669 1.6e-222 ywbN P Dyp-type peroxidase family protein
HMCIFNEL_01670 7.9e-184 ycdO P periplasmic lipoprotein involved in iron transport
HMCIFNEL_01671 1e-249 P COG0672 High-affinity Fe2 Pb2 permease
HMCIFNEL_01672 3.6e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMCIFNEL_01673 3.4e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMCIFNEL_01674 4.3e-153 ywbI K Transcriptional regulator
HMCIFNEL_01675 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HMCIFNEL_01676 2.3e-111 ywbG M effector of murein hydrolase
HMCIFNEL_01677 2.2e-205 ywbF EGP Major facilitator Superfamily
HMCIFNEL_01678 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
HMCIFNEL_01679 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
HMCIFNEL_01680 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HMCIFNEL_01681 2.3e-122 ywbB S Protein of unknown function (DUF2711)
HMCIFNEL_01682 1.8e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCIFNEL_01683 2e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
HMCIFNEL_01684 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMCIFNEL_01685 4e-153 sacY K transcriptional antiterminator
HMCIFNEL_01686 7e-169 gspA M General stress
HMCIFNEL_01687 1.2e-39 ywaF S Integral membrane protein
HMCIFNEL_01688 1.9e-64 ywaF S Integral membrane protein
HMCIFNEL_01689 8.1e-88 ywaE K Transcriptional regulator
HMCIFNEL_01690 2.2e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMCIFNEL_01691 8.3e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HMCIFNEL_01692 5.3e-92 K Helix-turn-helix XRE-family like proteins
HMCIFNEL_01693 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMCIFNEL_01694 1e-130 ynfM EGP Major facilitator Superfamily
HMCIFNEL_01695 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HMCIFNEL_01696 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HMCIFNEL_01697 5e-14 S D-Ala-teichoic acid biosynthesis protein
HMCIFNEL_01698 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCIFNEL_01699 2.7e-232 dltB M membrane protein involved in D-alanine export
HMCIFNEL_01700 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCIFNEL_01701 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMCIFNEL_01702 6.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_01703 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMCIFNEL_01704 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HMCIFNEL_01705 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HMCIFNEL_01706 1.2e-123 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCIFNEL_01707 9.9e-107 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMCIFNEL_01708 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HMCIFNEL_01709 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HMCIFNEL_01710 1.1e-19 yxzF
HMCIFNEL_01711 1.5e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMCIFNEL_01712 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HMCIFNEL_01713 2.5e-195 yxlH EGP Major facilitator Superfamily
HMCIFNEL_01714 1.5e-98 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMCIFNEL_01715 2.4e-147 yxlF V ABC transporter, ATP-binding protein
HMCIFNEL_01716 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HMCIFNEL_01717 4.9e-28
HMCIFNEL_01718 2.5e-39 yxlC S Family of unknown function (DUF5345)
HMCIFNEL_01719 1.4e-18 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_01720 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HMCIFNEL_01721 2.5e-96 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMCIFNEL_01722 0.0 cydD V ATP-binding protein
HMCIFNEL_01723 1.7e-310 cydD V ATP-binding
HMCIFNEL_01724 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HMCIFNEL_01725 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
HMCIFNEL_01726 6.1e-228 cimH C COG3493 Na citrate symporter
HMCIFNEL_01727 3.3e-308 3.4.24.84 O Peptidase family M48
HMCIFNEL_01729 1.6e-154 yxkH G Polysaccharide deacetylase
HMCIFNEL_01730 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HMCIFNEL_01731 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HMCIFNEL_01732 6.3e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMCIFNEL_01733 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMCIFNEL_01734 2.4e-73 yxkC S Domain of unknown function (DUF4352)
HMCIFNEL_01735 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMCIFNEL_01736 1e-76 S Protein of unknown function (DUF1453)
HMCIFNEL_01737 8.3e-192 yxjM T Signal transduction histidine kinase
HMCIFNEL_01738 7.1e-113 K helix_turn_helix, Lux Regulon
HMCIFNEL_01739 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMCIFNEL_01742 1.6e-85 yxjI S LURP-one-related
HMCIFNEL_01743 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
HMCIFNEL_01744 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
HMCIFNEL_01745 1.8e-90 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HMCIFNEL_01746 4.8e-26 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HMCIFNEL_01747 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HMCIFNEL_01748 9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HMCIFNEL_01749 9.8e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HMCIFNEL_01750 3.8e-159 rlmA 2.1.1.187 Q Methyltransferase domain
HMCIFNEL_01751 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMCIFNEL_01752 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HMCIFNEL_01753 3.3e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMCIFNEL_01754 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMCIFNEL_01755 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HMCIFNEL_01756 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_01757 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HMCIFNEL_01758 4.1e-242 icd 1.1.1.42 C isocitrate
HMCIFNEL_01759 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HMCIFNEL_01760 4.7e-71 yeaL S membrane
HMCIFNEL_01761 5.8e-192 ytvI S sporulation integral membrane protein YtvI
HMCIFNEL_01762 3.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HMCIFNEL_01763 4.9e-311 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMCIFNEL_01764 2.8e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMCIFNEL_01765 7.4e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HMCIFNEL_01766 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMCIFNEL_01767 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HMCIFNEL_01768 0.0 dnaE 2.7.7.7 L DNA polymerase
HMCIFNEL_01769 3.2e-56 ytrH S Sporulation protein YtrH
HMCIFNEL_01770 8.2e-69 ytrI
HMCIFNEL_01771 9.2e-29
HMCIFNEL_01772 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HMCIFNEL_01773 2.4e-47 ytpI S YtpI-like protein
HMCIFNEL_01774 2.3e-240 ytoI K transcriptional regulator containing CBS domains
HMCIFNEL_01775 2.3e-154 ytnM S membrane transporter protein
HMCIFNEL_01776 6.8e-186 ytnL 3.5.1.47 E hydrolase activity
HMCIFNEL_01777 1.4e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HMCIFNEL_01778 2e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMCIFNEL_01779 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HMCIFNEL_01780 1.2e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMCIFNEL_01781 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HMCIFNEL_01782 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
HMCIFNEL_01783 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HMCIFNEL_01784 5.8e-149 tcyK M Bacterial periplasmic substrate-binding proteins
HMCIFNEL_01785 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
HMCIFNEL_01786 4.7e-99 ytmI K Acetyltransferase (GNAT) domain
HMCIFNEL_01787 2.9e-173 ytlI K LysR substrate binding domain
HMCIFNEL_01788 3.9e-130 ytkL S Belongs to the UPF0173 family
HMCIFNEL_01789 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_01791 5.8e-266 argH 4.3.2.1 E argininosuccinate lyase
HMCIFNEL_01792 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMCIFNEL_01793 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HMCIFNEL_01794 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMCIFNEL_01795 3.3e-162 ytxK 2.1.1.72 L DNA methylase
HMCIFNEL_01796 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMCIFNEL_01797 1.5e-66 ytfJ S Sporulation protein YtfJ
HMCIFNEL_01798 9.6e-108 ytfI S Protein of unknown function (DUF2953)
HMCIFNEL_01799 1.5e-86 yteJ S RDD family
HMCIFNEL_01800 1.1e-178 sppA OU signal peptide peptidase SppA
HMCIFNEL_01801 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMCIFNEL_01802 0.0 ytcJ S amidohydrolase
HMCIFNEL_01803 1.2e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HMCIFNEL_01804 2.2e-28 sspB S spore protein
HMCIFNEL_01805 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMCIFNEL_01806 9.2e-209 iscS2 2.8.1.7 E Cysteine desulfurase
HMCIFNEL_01807 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
HMCIFNEL_01808 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMCIFNEL_01809 6.6e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HMCIFNEL_01810 6.5e-108 yttP K Transcriptional regulator
HMCIFNEL_01811 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HMCIFNEL_01812 3.2e-36 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMCIFNEL_01813 2.4e-40 yfnD M Nucleotide-diphospho-sugar transferase
HMCIFNEL_01815 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HMCIFNEL_01816 3.6e-140 ycsF S Belongs to the UPF0271 (lamB) family
HMCIFNEL_01817 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HMCIFNEL_01818 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HMCIFNEL_01819 1.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HMCIFNEL_01820 1.4e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HMCIFNEL_01821 1.3e-131 kipR K Transcriptional regulator
HMCIFNEL_01822 8.4e-119 ycsK E anatomical structure formation involved in morphogenesis
HMCIFNEL_01824 6.9e-32 yczJ S biosynthesis
HMCIFNEL_01826 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HMCIFNEL_01827 9.2e-172 ydhF S Oxidoreductase
HMCIFNEL_01828 0.0 mtlR K transcriptional regulator, MtlR
HMCIFNEL_01829 1.8e-292 ydaB IQ acyl-CoA ligase
HMCIFNEL_01830 2.2e-97 ydaC Q Methyltransferase domain
HMCIFNEL_01831 7e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_01832 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HMCIFNEL_01833 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMCIFNEL_01834 6.8e-77 ydaG 1.4.3.5 S general stress protein
HMCIFNEL_01835 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HMCIFNEL_01836 3.6e-45 ydzA EGP Major facilitator Superfamily
HMCIFNEL_01837 2.5e-74 lrpC K Transcriptional regulator
HMCIFNEL_01838 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMCIFNEL_01839 1.4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HMCIFNEL_01840 1.2e-89 ydaK T Diguanylate cyclase, GGDEF domain
HMCIFNEL_01841 3.9e-30 ydaK T Diguanylate cyclase, GGDEF domain
HMCIFNEL_01842 5e-132 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HMCIFNEL_01843 1e-176 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HMCIFNEL_01844 5.9e-233 ydaM M Glycosyl transferase family group 2
HMCIFNEL_01845 1e-185 ydaN S Bacterial cellulose synthase subunit
HMCIFNEL_01846 3.5e-186 ydaN S Bacterial cellulose synthase subunit
HMCIFNEL_01847 0.0 ydaO E amino acid
HMCIFNEL_01848 5.2e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HMCIFNEL_01849 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMCIFNEL_01850 3.6e-39
HMCIFNEL_01851 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HMCIFNEL_01853 3.7e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HMCIFNEL_01854 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HMCIFNEL_01856 2.6e-58 ydbB G Cupin domain
HMCIFNEL_01857 2.6e-61 ydbC S Domain of unknown function (DUF4937
HMCIFNEL_01858 1.2e-138 ydbD P Catalase
HMCIFNEL_01859 1.1e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HMCIFNEL_01860 1.5e-294 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HMCIFNEL_01861 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HMCIFNEL_01862 3.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMCIFNEL_01863 2.8e-180 ydbI S AI-2E family transporter
HMCIFNEL_01864 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
HMCIFNEL_01865 2.1e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMCIFNEL_01866 2.7e-52 ydbL
HMCIFNEL_01867 4.8e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HMCIFNEL_01868 1.1e-18 S Fur-regulated basic protein B
HMCIFNEL_01869 2.2e-07 S Fur-regulated basic protein A
HMCIFNEL_01870 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMCIFNEL_01871 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMCIFNEL_01872 5.6e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMCIFNEL_01873 5.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMCIFNEL_01874 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMCIFNEL_01875 2.1e-82 ydbS S Bacterial PH domain
HMCIFNEL_01876 8.6e-260 ydbT S Membrane
HMCIFNEL_01877 9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HMCIFNEL_01878 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMCIFNEL_01879 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HMCIFNEL_01880 3.7e-48 tldD S 'responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase
HMCIFNEL_01881 2.9e-76 ctsR K Belongs to the CtsR family
HMCIFNEL_01882 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HMCIFNEL_01883 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HMCIFNEL_01884 0.0 clpC O Belongs to the ClpA ClpB family
HMCIFNEL_01885 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMCIFNEL_01886 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HMCIFNEL_01887 1.7e-196 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HMCIFNEL_01888 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HMCIFNEL_01889 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HMCIFNEL_01890 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMCIFNEL_01891 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HMCIFNEL_01892 2.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMCIFNEL_01893 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMCIFNEL_01894 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMCIFNEL_01895 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HMCIFNEL_01896 4.4e-115 sigH K Belongs to the sigma-70 factor family
HMCIFNEL_01897 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMCIFNEL_01898 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HMCIFNEL_01899 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMCIFNEL_01900 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMCIFNEL_01901 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMCIFNEL_01902 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMCIFNEL_01903 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HMCIFNEL_01904 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCIFNEL_01905 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCIFNEL_01906 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HMCIFNEL_01907 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMCIFNEL_01908 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMCIFNEL_01909 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMCIFNEL_01910 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMCIFNEL_01911 1.7e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HMCIFNEL_01912 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMCIFNEL_01913 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMCIFNEL_01914 3e-105 rplD J Forms part of the polypeptide exit tunnel
HMCIFNEL_01915 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMCIFNEL_01916 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMCIFNEL_01917 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMCIFNEL_01918 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMCIFNEL_01919 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMCIFNEL_01920 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMCIFNEL_01921 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HMCIFNEL_01922 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMCIFNEL_01923 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMCIFNEL_01924 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMCIFNEL_01925 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMCIFNEL_01926 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMCIFNEL_01927 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMCIFNEL_01928 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMCIFNEL_01929 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMCIFNEL_01930 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMCIFNEL_01931 1.9e-23 rpmD J Ribosomal protein L30
HMCIFNEL_01932 1.8e-72 rplO J binds to the 23S rRNA
HMCIFNEL_01933 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMCIFNEL_01934 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMCIFNEL_01935 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HMCIFNEL_01936 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMCIFNEL_01937 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMCIFNEL_01938 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMCIFNEL_01939 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMCIFNEL_01940 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCIFNEL_01941 3.6e-58 rplQ J Ribosomal protein L17
HMCIFNEL_01942 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCIFNEL_01943 8.8e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCIFNEL_01944 2.6e-117 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCIFNEL_01945 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMCIFNEL_01946 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMCIFNEL_01947 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HMCIFNEL_01948 1.2e-143 ybaJ Q Methyltransferase domain
HMCIFNEL_01949 3.5e-71 ybaK S Protein of unknown function (DUF2521)
HMCIFNEL_01950 2.8e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMCIFNEL_01951 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HMCIFNEL_01952 1.2e-84 gerD
HMCIFNEL_01953 1.5e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HMCIFNEL_01954 3.5e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HMCIFNEL_01955 1.7e-42 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMCIFNEL_01956 4.5e-19 L nucleic acid phosphodiester bond hydrolysis
HMCIFNEL_01957 3.4e-33 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HMCIFNEL_01958 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCIFNEL_01959 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HMCIFNEL_01960 4.9e-139 srfAD Q thioesterase
HMCIFNEL_01961 4.4e-225 EGP Major Facilitator Superfamily
HMCIFNEL_01962 4.8e-86 S YcxB-like protein
HMCIFNEL_01963 5.8e-161 ycxC EG EamA-like transporter family
HMCIFNEL_01964 8.9e-237 ycxD K GntR family transcriptional regulator
HMCIFNEL_01965 9.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HMCIFNEL_01966 9.7e-115 yczE S membrane
HMCIFNEL_01967 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HMCIFNEL_01968 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HMCIFNEL_01969 8.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HMCIFNEL_01970 1.1e-158 bsdA K LysR substrate binding domain
HMCIFNEL_01971 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HMCIFNEL_01972 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HMCIFNEL_01973 4e-39 bsdD 4.1.1.61 S response to toxic substance
HMCIFNEL_01974 2.7e-82 yclD
HMCIFNEL_01975 6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
HMCIFNEL_01976 7.3e-267 dtpT E amino acid peptide transporter
HMCIFNEL_01977 1.9e-298 yclG M Pectate lyase superfamily protein
HMCIFNEL_01979 1.9e-276 gerKA EG Spore germination protein
HMCIFNEL_01980 8e-227 gerKC S spore germination
HMCIFNEL_01981 1e-196 gerKB F Spore germination protein
HMCIFNEL_01982 1.5e-121 yclH P ABC transporter
HMCIFNEL_01983 4e-201 yclI V ABC transporter (permease) YclI
HMCIFNEL_01984 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_01985 1.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMCIFNEL_01986 1.4e-71 S aspartate phosphatase
HMCIFNEL_01990 2.8e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMCIFNEL_01991 3e-35 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_01992 5.8e-98 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_01993 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_01994 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HMCIFNEL_01995 1.5e-172 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HMCIFNEL_01996 1.4e-251 ycnB EGP Major facilitator Superfamily
HMCIFNEL_01997 7.9e-152 ycnC K Transcriptional regulator
HMCIFNEL_01998 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HMCIFNEL_01999 1.6e-45 ycnE S Monooxygenase
HMCIFNEL_02000 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HMCIFNEL_02001 3.6e-271 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCIFNEL_02002 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMCIFNEL_02003 1.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMCIFNEL_02004 6.1e-149 glcU U Glucose uptake
HMCIFNEL_02005 1.4e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_02006 6.6e-97 ycnI S protein conserved in bacteria
HMCIFNEL_02007 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
HMCIFNEL_02008 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HMCIFNEL_02009 2.6e-53
HMCIFNEL_02010 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HMCIFNEL_02011 2.4e-69 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HMCIFNEL_02012 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HMCIFNEL_02013 1.1e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HMCIFNEL_02014 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HMCIFNEL_02015 6e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HMCIFNEL_02016 8.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HMCIFNEL_02017 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HMCIFNEL_02018 2.6e-53 L COG3328 Transposase and inactivated derivatives
HMCIFNEL_02019 2.7e-53 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_02020 4.7e-37 yvkA EGP Major facilitator Superfamily
HMCIFNEL_02022 5.6e-134 M Membrane
HMCIFNEL_02023 2.4e-30 yetM CH FAD binding domain
HMCIFNEL_02024 9.1e-105 yetJ S Belongs to the BI1 family
HMCIFNEL_02025 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HMCIFNEL_02026 2.7e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMCIFNEL_02027 1.1e-33
HMCIFNEL_02028 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCIFNEL_02029 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HMCIFNEL_02030 1.7e-120 yetF S membrane
HMCIFNEL_02031 4.6e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HMCIFNEL_02032 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
HMCIFNEL_02033 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HMCIFNEL_02034 9e-289 lplA G Bacterial extracellular solute-binding protein
HMCIFNEL_02035 0.0 yetA
HMCIFNEL_02036 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HMCIFNEL_02037 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HMCIFNEL_02038 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HMCIFNEL_02039 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HMCIFNEL_02040 2.4e-110 yesV S Protein of unknown function, DUF624
HMCIFNEL_02041 2.8e-125 yesU S Domain of unknown function (DUF1961)
HMCIFNEL_02042 9.7e-129 E GDSL-like Lipase/Acylhydrolase
HMCIFNEL_02043 0.0 yesS K Transcriptional regulator
HMCIFNEL_02044 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HMCIFNEL_02045 2.4e-89 yesQ P Binding-protein-dependent transport system inner membrane component
HMCIFNEL_02046 1.9e-60 yesQ P Binding-protein-dependent transport system inner membrane component
HMCIFNEL_02047 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
HMCIFNEL_02048 3.6e-246 yesO G Bacterial extracellular solute-binding protein
HMCIFNEL_02049 3.6e-73 yesN K helix_turn_helix, arabinose operon control protein
HMCIFNEL_02050 8.2e-114 yesN K helix_turn_helix, arabinose operon control protein
HMCIFNEL_02051 0.0 yesM 2.7.13.3 T Histidine kinase
HMCIFNEL_02052 5e-100 yesL S Protein of unknown function, DUF624
HMCIFNEL_02054 6e-102 yesJ K Acetyltransferase (GNAT) family
HMCIFNEL_02055 2e-103 cotJC P Spore Coat
HMCIFNEL_02056 5.6e-45 cotJB S CotJB protein
HMCIFNEL_02057 6.9e-45 cotJA S Spore coat associated protein JA (CotJA)
HMCIFNEL_02058 6.7e-99 dhaR3 K Transcriptional regulator
HMCIFNEL_02060 2.7e-126 yeeN K transcriptional regulatory protein
HMCIFNEL_02062 7.4e-211 S Tetratricopeptide repeat
HMCIFNEL_02063 3.6e-58 3.4.24.40 CO amine dehydrogenase activity
HMCIFNEL_02064 5.9e-96 3.4.24.40 CO amine dehydrogenase activity
HMCIFNEL_02065 0.0 L nucleic acid phosphodiester bond hydrolysis
HMCIFNEL_02066 2.7e-82 S Protein of unknown function, DUF600
HMCIFNEL_02068 2.6e-29 S Colicin immunity protein / pyocin immunity protein
HMCIFNEL_02070 3.7e-101 S response regulator aspartate phosphatase
HMCIFNEL_02072 1.9e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCIFNEL_02073 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMCIFNEL_02074 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMCIFNEL_02075 7.4e-147 yerO K Transcriptional regulator
HMCIFNEL_02076 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMCIFNEL_02077 1e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMCIFNEL_02078 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMCIFNEL_02079 2.1e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMCIFNEL_02080 1.6e-123 sapB S MgtC SapB transporter
HMCIFNEL_02081 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
HMCIFNEL_02082 2.2e-09 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HMCIFNEL_02083 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HMCIFNEL_02084 2.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HMCIFNEL_02085 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HMCIFNEL_02086 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HMCIFNEL_02087 1.2e-178 ykvI S membrane
HMCIFNEL_02088 0.0 clpE O Belongs to the ClpA ClpB family
HMCIFNEL_02089 5.1e-137 motA N flagellar motor
HMCIFNEL_02090 1.5e-122 motB N Flagellar motor protein
HMCIFNEL_02091 1.3e-75 ykvE K transcriptional
HMCIFNEL_02092 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HMCIFNEL_02093 1.1e-61 eag
HMCIFNEL_02094 6.4e-09 S Spo0E like sporulation regulatory protein
HMCIFNEL_02095 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HMCIFNEL_02096 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HMCIFNEL_02097 2.6e-112 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HMCIFNEL_02098 3.5e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HMCIFNEL_02099 2.2e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HMCIFNEL_02100 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
HMCIFNEL_02101 1.3e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMCIFNEL_02102 8.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HMCIFNEL_02103 4.8e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HMCIFNEL_02105 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMCIFNEL_02106 0.0 kinE 2.7.13.3 T Histidine kinase
HMCIFNEL_02107 1.6e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HMCIFNEL_02108 4.1e-18 ykzE
HMCIFNEL_02109 1.2e-10 ydfR S Protein of unknown function (DUF421)
HMCIFNEL_02110 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HMCIFNEL_02111 3.5e-155 htpX O Belongs to the peptidase M48B family
HMCIFNEL_02112 1.9e-124 ykrK S Domain of unknown function (DUF1836)
HMCIFNEL_02113 1.9e-26 sspD S small acid-soluble spore protein
HMCIFNEL_02114 7.2e-113 rsgI S Anti-sigma factor N-terminus
HMCIFNEL_02115 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCIFNEL_02116 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HMCIFNEL_02117 2.7e-109 ykoX S membrane-associated protein
HMCIFNEL_02118 1.9e-64 ydcR 2.7.7.65 T Diguanylate cyclase
HMCIFNEL_02119 5.8e-62 ydcR 2.7.7.65 T Diguanylate cyclase
HMCIFNEL_02120 2.9e-108 ydcR 2.7.7.65 T Diguanylate cyclase
HMCIFNEL_02121 8.6e-27 ydcR 2.7.7.65 T Diguanylate cyclase
HMCIFNEL_02122 3.4e-58 ydcR 2.7.7.65 T Diguanylate cyclase
HMCIFNEL_02123 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HMCIFNEL_02124 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HMCIFNEL_02125 3.1e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMCIFNEL_02126 0.0 ykoS
HMCIFNEL_02127 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HMCIFNEL_02128 6.3e-97 ykoP G polysaccharide deacetylase
HMCIFNEL_02129 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HMCIFNEL_02130 1.3e-81 mhqR K transcriptional
HMCIFNEL_02131 6.9e-26 ykoL
HMCIFNEL_02132 5.9e-18
HMCIFNEL_02133 1.4e-53 tnrA K transcriptional
HMCIFNEL_02134 2.2e-222 mgtE P Acts as a magnesium transporter
HMCIFNEL_02137 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
HMCIFNEL_02138 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
HMCIFNEL_02139 5.4e-240 ykoH 2.7.13.3 T Histidine kinase
HMCIFNEL_02140 6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_02141 7.4e-109 ykoF S YKOF-related Family
HMCIFNEL_02142 1.2e-98 ykoE S ABC-type cobalt transport system, permease component
HMCIFNEL_02143 5.7e-305 P ABC transporter, ATP-binding protein
HMCIFNEL_02144 7.6e-135 ykoC P Cobalt transport protein
HMCIFNEL_02145 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMCIFNEL_02146 1.5e-175 isp O Belongs to the peptidase S8 family
HMCIFNEL_02147 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMCIFNEL_02149 1.8e-45 braB E Component of the transport system for branched-chain amino acids
HMCIFNEL_02150 3.8e-40 ccpA K catabolite control protein A
HMCIFNEL_02151 1.5e-23 pbpX V Beta-lactamase
HMCIFNEL_02152 1.3e-72 L Integrase core domain
HMCIFNEL_02153 2.6e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMCIFNEL_02154 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMCIFNEL_02155 2.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HMCIFNEL_02156 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMCIFNEL_02157 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMCIFNEL_02158 4.5e-88 yaiI S Belongs to the UPF0178 family
HMCIFNEL_02159 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMCIFNEL_02160 4.5e-112 ccpN K CBS domain
HMCIFNEL_02161 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMCIFNEL_02162 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMCIFNEL_02163 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
HMCIFNEL_02164 8.4e-19 S YqzL-like protein
HMCIFNEL_02165 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMCIFNEL_02166 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMCIFNEL_02167 2.5e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMCIFNEL_02168 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMCIFNEL_02169 0.0 yqfF S membrane-associated HD superfamily hydrolase
HMCIFNEL_02171 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HMCIFNEL_02172 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HMCIFNEL_02173 2.7e-45 yqfC S sporulation protein YqfC
HMCIFNEL_02174 6e-25 yqfB
HMCIFNEL_02175 4.3e-122 yqfA S UPF0365 protein
HMCIFNEL_02176 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HMCIFNEL_02177 2.5e-61 yqeY S Yqey-like protein
HMCIFNEL_02178 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMCIFNEL_02179 8.1e-155 yqeW P COG1283 Na phosphate symporter
HMCIFNEL_02180 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HMCIFNEL_02181 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMCIFNEL_02182 5.4e-175 prmA J Methylates ribosomal protein L11
HMCIFNEL_02183 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMCIFNEL_02184 0.0 dnaK O Heat shock 70 kDa protein
HMCIFNEL_02185 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMCIFNEL_02186 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMCIFNEL_02187 1.7e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HMCIFNEL_02188 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMCIFNEL_02189 7.2e-53 yqxA S Protein of unknown function (DUF3679)
HMCIFNEL_02190 1.5e-222 spoIIP M stage II sporulation protein P
HMCIFNEL_02191 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HMCIFNEL_02192 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HMCIFNEL_02193 6.2e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
HMCIFNEL_02194 4.1e-15 S YqzM-like protein
HMCIFNEL_02195 0.0 comEC S Competence protein ComEC
HMCIFNEL_02196 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HMCIFNEL_02197 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HMCIFNEL_02198 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMCIFNEL_02199 1.4e-138 yqeM Q Methyltransferase
HMCIFNEL_02200 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMCIFNEL_02201 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HMCIFNEL_02202 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMCIFNEL_02203 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HMCIFNEL_02204 3.3e-155 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMCIFNEL_02205 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HMCIFNEL_02206 5.3e-95 yqeG S hydrolase of the HAD superfamily
HMCIFNEL_02208 1.4e-141 yqeF E GDSL-like Lipase/Acylhydrolase
HMCIFNEL_02209 7e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMCIFNEL_02210 8.8e-105 yqeD S SNARE associated Golgi protein
HMCIFNEL_02211 5e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HMCIFNEL_02212 6.3e-131 yqeB
HMCIFNEL_02213 1.6e-35 nucB M Deoxyribonuclease NucA/NucB
HMCIFNEL_02214 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCIFNEL_02215 1e-52 yceG S Putative component of 'biosynthetic module'
HMCIFNEL_02216 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMCIFNEL_02217 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMCIFNEL_02218 4.1e-30 yazB K transcriptional
HMCIFNEL_02219 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMCIFNEL_02220 2.2e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMCIFNEL_02221 1.9e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMCIFNEL_02222 1.9e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HMCIFNEL_02223 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HMCIFNEL_02224 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMCIFNEL_02225 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMCIFNEL_02226 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HMCIFNEL_02227 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMCIFNEL_02228 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HMCIFNEL_02229 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMCIFNEL_02230 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMCIFNEL_02231 3.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMCIFNEL_02232 3.7e-185 KLT serine threonine protein kinase
HMCIFNEL_02233 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HMCIFNEL_02234 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HMCIFNEL_02237 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HMCIFNEL_02238 1.1e-44 divIC D Septum formation initiator
HMCIFNEL_02239 4.3e-107 yabQ S spore cortex biosynthesis protein
HMCIFNEL_02240 1.5e-49 yabP S Sporulation protein YabP
HMCIFNEL_02241 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HMCIFNEL_02242 8.6e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HMCIFNEL_02243 7.8e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMCIFNEL_02244 1.5e-92 spoVT K stage V sporulation protein
HMCIFNEL_02245 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMCIFNEL_02246 2.4e-39 yabK S Peptide ABC transporter permease
HMCIFNEL_02247 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMCIFNEL_02248 4.3e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HMCIFNEL_02249 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMCIFNEL_02250 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMCIFNEL_02251 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HMCIFNEL_02252 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HMCIFNEL_02253 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HMCIFNEL_02254 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMCIFNEL_02255 2e-26 sspF S DNA topological change
HMCIFNEL_02256 7.8e-39 veg S protein conserved in bacteria
HMCIFNEL_02257 1.6e-136 yabG S peptidase
HMCIFNEL_02258 4.2e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMCIFNEL_02259 7.9e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMCIFNEL_02260 3.2e-165 rpfB GH23 T protein conserved in bacteria
HMCIFNEL_02261 1.7e-142 tatD L hydrolase, TatD
HMCIFNEL_02262 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMCIFNEL_02263 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HMCIFNEL_02264 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMCIFNEL_02265 1.5e-49 yazA L endonuclease containing a URI domain
HMCIFNEL_02266 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HMCIFNEL_02267 4.8e-31 yabA L Involved in initiation control of chromosome replication
HMCIFNEL_02268 6.1e-146 yaaT S stage 0 sporulation protein
HMCIFNEL_02269 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HMCIFNEL_02270 1e-70 yaaR S protein conserved in bacteria
HMCIFNEL_02271 2.2e-54 yaaQ S protein conserved in bacteria
HMCIFNEL_02272 2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMCIFNEL_02273 4.8e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HMCIFNEL_02274 2.2e-202 yaaN P Belongs to the TelA family
HMCIFNEL_02275 2.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HMCIFNEL_02276 3.4e-31 csfB S Inhibitor of sigma-G Gin
HMCIFNEL_02277 3.3e-73 ytfM M COG0729 Outer membrane protein
HMCIFNEL_02279 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMCIFNEL_02280 4.4e-289 lctP C L-lactate permease
HMCIFNEL_02281 3.9e-263 mdr EGP Major facilitator Superfamily
HMCIFNEL_02282 2.2e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HMCIFNEL_02283 4.5e-109 ycgF E Lysine exporter protein LysE YggA
HMCIFNEL_02284 1.4e-149 yqcI S YqcI/YcgG family
HMCIFNEL_02285 2.4e-153 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HMCIFNEL_02286 4.3e-94 ycgI S Domain of unknown function (DUF1989)
HMCIFNEL_02287 1.7e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMCIFNEL_02288 2.6e-86 tmrB S AAA domain
HMCIFNEL_02289 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMCIFNEL_02290 2.2e-142 yafE Q ubiE/COQ5 methyltransferase family
HMCIFNEL_02291 2.2e-179 oxyR3 K LysR substrate binding domain
HMCIFNEL_02292 5.5e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HMCIFNEL_02293 2.9e-145 ycgL S Predicted nucleotidyltransferase
HMCIFNEL_02294 5.1e-170 ycgM E Proline dehydrogenase
HMCIFNEL_02295 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HMCIFNEL_02296 7.5e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMCIFNEL_02297 3.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HMCIFNEL_02298 2.6e-147 ycgQ S membrane
HMCIFNEL_02299 6.5e-138 ycgR S permeases
HMCIFNEL_02300 8.5e-159 I alpha/beta hydrolase fold
HMCIFNEL_02301 1.9e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HMCIFNEL_02302 5.4e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HMCIFNEL_02303 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HMCIFNEL_02304 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HMCIFNEL_02305 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMCIFNEL_02306 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HMCIFNEL_02307 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
HMCIFNEL_02308 1.2e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HMCIFNEL_02309 4.2e-101 yciB M ErfK YbiS YcfS YnhG
HMCIFNEL_02310 3.6e-112 yciC S GTPases (G3E family)
HMCIFNEL_02311 1.8e-98 yciC S GTPases (G3E family)
HMCIFNEL_02312 1e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
HMCIFNEL_02313 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMCIFNEL_02315 3.7e-42 yckC S membrane
HMCIFNEL_02316 7.8e-52 yckD S Protein of unknown function (DUF2680)
HMCIFNEL_02317 2e-21 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMCIFNEL_02318 4.8e-248 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMCIFNEL_02319 8.5e-69 nin S Competence protein J (ComJ)
HMCIFNEL_02320 5.6e-69 nucA M Deoxyribonuclease NucA/NucB
HMCIFNEL_02321 2.7e-56 tlpC 2.7.13.3 NT chemotaxis protein
HMCIFNEL_02322 7.8e-115 tlpC 2.7.13.3 NT chemotaxis protein
HMCIFNEL_02323 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HMCIFNEL_02324 4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HMCIFNEL_02325 6.3e-63 hxlR K transcriptional
HMCIFNEL_02326 1.2e-49 plsC 2.3.1.51, 3.1.3.3 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HMCIFNEL_02327 7.5e-31 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMCIFNEL_02328 2e-18 mleA 1.1.1.38 C malic enzyme
HMCIFNEL_02329 1.8e-44 scrK 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
HMCIFNEL_02330 1.9e-25 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMCIFNEL_02331 1.8e-09
HMCIFNEL_02332 2.5e-145 dnaG 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMCIFNEL_02333 9.5e-59 L DNA primase activity
HMCIFNEL_02334 9.6e-122 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMCIFNEL_02335 6.4e-20 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMCIFNEL_02336 6.1e-110 DR0488 S protein conserved in bacteria
HMCIFNEL_02341 4.1e-81 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HMCIFNEL_02343 2.6e-163 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HMCIFNEL_02354 7.5e-77 yhdJ 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HMCIFNEL_02358 2.8e-64 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HMCIFNEL_02359 3.5e-113 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCIFNEL_02360 1.7e-48 S HNH endonuclease
HMCIFNEL_02361 2.3e-226 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCIFNEL_02362 2.2e-54 S Protein of unknown function (DUF1140)
HMCIFNEL_02363 1.7e-100 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCIFNEL_02366 3.6e-30 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCIFNEL_02367 1.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HMCIFNEL_02372 6.8e-161 S Thymidylate synthase
HMCIFNEL_02373 5.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMCIFNEL_02375 1.2e-35
HMCIFNEL_02377 1.6e-29 sspB S spore protein
HMCIFNEL_02381 8.4e-11 K Cro/C1-type HTH DNA-binding domain
HMCIFNEL_02382 2.3e-102 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMCIFNEL_02384 1.1e-62 4.2.1.115 GM Polysaccharide biosynthesis protein
HMCIFNEL_02385 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HMCIFNEL_02386 1.4e-186 cgeB S Spore maturation protein
HMCIFNEL_02387 4.8e-64 cgeA
HMCIFNEL_02388 5.9e-38 cgeC
HMCIFNEL_02389 8e-254 cgeD M maturation of the outermost layer of the spore
HMCIFNEL_02390 9.2e-144 yiiD K acetyltransferase
HMCIFNEL_02392 2.1e-238 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMCIFNEL_02393 2.4e-09 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HMCIFNEL_02394 5.2e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HMCIFNEL_02395 1.2e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
HMCIFNEL_02396 8.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HMCIFNEL_02397 1.4e-275 kamA 5.4.3.2 E lysine 2,3-aminomutase
HMCIFNEL_02398 2.9e-47 yokU S YokU-like protein, putative antitoxin
HMCIFNEL_02399 3.1e-36 yozE S Belongs to the UPF0346 family
HMCIFNEL_02400 6e-123 yodN
HMCIFNEL_02402 2.8e-24 yozD S YozD-like protein
HMCIFNEL_02403 6.6e-105 yodM 3.6.1.27 I Acid phosphatase homologues
HMCIFNEL_02404 7.9e-54 yodL S YodL-like
HMCIFNEL_02405 5.3e-09
HMCIFNEL_02406 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HMCIFNEL_02407 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HMCIFNEL_02408 2e-23 yodI
HMCIFNEL_02409 2.4e-127 yodH Q Methyltransferase
HMCIFNEL_02410 9.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HMCIFNEL_02411 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMCIFNEL_02412 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HMCIFNEL_02413 2.7e-111 mhqD S Carboxylesterase
HMCIFNEL_02414 1.7e-69 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMCIFNEL_02415 8.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HMCIFNEL_02416 0.0 ylaA
HMCIFNEL_02417 3e-41 ylaB
HMCIFNEL_02418 1.3e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_02419 7e-12 sigC S Putative zinc-finger
HMCIFNEL_02420 4.1e-38 ylaE
HMCIFNEL_02421 8.2e-22 S Family of unknown function (DUF5325)
HMCIFNEL_02422 0.0 typA T GTP-binding protein TypA
HMCIFNEL_02423 4.2e-47 ylaH S YlaH-like protein
HMCIFNEL_02424 2.5e-32 ylaI S protein conserved in bacteria
HMCIFNEL_02425 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMCIFNEL_02426 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HMCIFNEL_02427 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HMCIFNEL_02428 1.4e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
HMCIFNEL_02429 8.7e-44 ylaN S Belongs to the UPF0358 family
HMCIFNEL_02430 1.5e-209 ftsW D Belongs to the SEDS family
HMCIFNEL_02431 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMCIFNEL_02432 2.2e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HMCIFNEL_02433 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HMCIFNEL_02434 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HMCIFNEL_02435 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMCIFNEL_02436 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HMCIFNEL_02437 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HMCIFNEL_02438 7e-164 ctaG S cytochrome c oxidase
HMCIFNEL_02439 7.7e-61 ylbA S YugN-like family
HMCIFNEL_02440 5.7e-74 ylbB T COG0517 FOG CBS domain
HMCIFNEL_02441 7.4e-200 ylbC S protein with SCP PR1 domains
HMCIFNEL_02442 4.1e-63 ylbD S Putative coat protein
HMCIFNEL_02443 6.7e-37 ylbE S YlbE-like protein
HMCIFNEL_02444 1.8e-75 ylbF S Belongs to the UPF0342 family
HMCIFNEL_02445 3.7e-38 ylbG S UPF0298 protein
HMCIFNEL_02446 2.5e-95 rsmD 2.1.1.171 L Methyltransferase
HMCIFNEL_02447 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMCIFNEL_02448 3.2e-220 ylbJ S Sporulation integral membrane protein YlbJ
HMCIFNEL_02449 6.4e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
HMCIFNEL_02450 2.6e-186 ylbL T Belongs to the peptidase S16 family
HMCIFNEL_02451 2.8e-235 ylbM S Belongs to the UPF0348 family
HMCIFNEL_02453 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HMCIFNEL_02454 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMCIFNEL_02455 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HMCIFNEL_02456 1.5e-88 ylbP K n-acetyltransferase
HMCIFNEL_02457 2.9e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMCIFNEL_02458 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HMCIFNEL_02459 2.9e-78 mraZ K Belongs to the MraZ family
HMCIFNEL_02460 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMCIFNEL_02461 3.7e-44 ftsL D Essential cell division protein
HMCIFNEL_02462 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMCIFNEL_02463 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HMCIFNEL_02464 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMCIFNEL_02465 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMCIFNEL_02466 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMCIFNEL_02467 5.7e-186 spoVE D Belongs to the SEDS family
HMCIFNEL_02468 9.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMCIFNEL_02469 5.3e-167 murB 1.3.1.98 M cell wall formation
HMCIFNEL_02470 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMCIFNEL_02471 5.4e-103 ylxW S protein conserved in bacteria
HMCIFNEL_02472 3.1e-116 ylxX S protein conserved in bacteria
HMCIFNEL_02473 1.4e-57 sbp S small basic protein
HMCIFNEL_02474 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMCIFNEL_02475 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMCIFNEL_02476 0.0 bpr O COG1404 Subtilisin-like serine proteases
HMCIFNEL_02477 1.6e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HMCIFNEL_02478 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCIFNEL_02479 6.8e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCIFNEL_02480 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HMCIFNEL_02481 2.2e-251 argE 3.5.1.16 E Acetylornithine deacetylase
HMCIFNEL_02482 2.4e-37 ylmC S sporulation protein
HMCIFNEL_02483 1.7e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HMCIFNEL_02484 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMCIFNEL_02485 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMCIFNEL_02486 1.3e-39 yggT S membrane
HMCIFNEL_02487 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HMCIFNEL_02488 2.6e-67 divIVA D Cell division initiation protein
HMCIFNEL_02489 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMCIFNEL_02490 1.3e-63 dksA T COG1734 DnaK suppressor protein
HMCIFNEL_02491 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMCIFNEL_02492 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMCIFNEL_02493 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMCIFNEL_02494 2.6e-231 pyrP F Xanthine uracil
HMCIFNEL_02495 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMCIFNEL_02496 3.5e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMCIFNEL_02497 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMCIFNEL_02498 0.0 carB 6.3.5.5 F Belongs to the CarB family
HMCIFNEL_02499 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HMCIFNEL_02500 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMCIFNEL_02501 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMCIFNEL_02502 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMCIFNEL_02503 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HMCIFNEL_02504 1.4e-179 cysP P phosphate transporter
HMCIFNEL_02505 4.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HMCIFNEL_02506 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HMCIFNEL_02507 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HMCIFNEL_02508 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HMCIFNEL_02509 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HMCIFNEL_02510 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HMCIFNEL_02511 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HMCIFNEL_02512 2.4e-156 yloC S stress-induced protein
HMCIFNEL_02513 6e-17 ylzA S Belongs to the UPF0296 family
HMCIFNEL_02514 3.8e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMCIFNEL_02515 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMCIFNEL_02516 1.6e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMCIFNEL_02517 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMCIFNEL_02518 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMCIFNEL_02519 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMCIFNEL_02520 9.3e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMCIFNEL_02521 4.1e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMCIFNEL_02522 1.6e-140 stp 3.1.3.16 T phosphatase
HMCIFNEL_02523 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HMCIFNEL_02524 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMCIFNEL_02525 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMCIFNEL_02526 2e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMCIFNEL_02527 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMCIFNEL_02528 5.5e-59 asp S protein conserved in bacteria
HMCIFNEL_02529 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
HMCIFNEL_02530 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HMCIFNEL_02531 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HMCIFNEL_02532 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMCIFNEL_02533 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HMCIFNEL_02534 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMCIFNEL_02535 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HMCIFNEL_02536 6.1e-129 IQ reductase
HMCIFNEL_02537 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMCIFNEL_02538 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMCIFNEL_02539 0.0 smc D Required for chromosome condensation and partitioning
HMCIFNEL_02540 1.3e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMCIFNEL_02541 3.2e-125 S Phosphotransferase enzyme family
HMCIFNEL_02542 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMCIFNEL_02543 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMCIFNEL_02544 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMCIFNEL_02545 4.5e-36 ylqC S Belongs to the UPF0109 family
HMCIFNEL_02546 1.4e-60 ylqD S YlqD protein
HMCIFNEL_02547 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMCIFNEL_02548 1.3e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMCIFNEL_02549 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMCIFNEL_02550 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMCIFNEL_02551 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMCIFNEL_02552 2.7e-289 ylqG
HMCIFNEL_02553 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HMCIFNEL_02554 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HMCIFNEL_02555 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HMCIFNEL_02556 8e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HMCIFNEL_02557 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMCIFNEL_02558 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMCIFNEL_02559 2.5e-169 xerC L tyrosine recombinase XerC
HMCIFNEL_02560 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMCIFNEL_02561 2.2e-249 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMCIFNEL_02562 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HMCIFNEL_02563 3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HMCIFNEL_02564 7.6e-74 flgC N Belongs to the flagella basal body rod proteins family
HMCIFNEL_02565 1.9e-31 fliE N Flagellar hook-basal body
HMCIFNEL_02566 9.1e-255 fliF N The M ring may be actively involved in energy transduction
HMCIFNEL_02567 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HMCIFNEL_02568 9.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HMCIFNEL_02569 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HMCIFNEL_02570 4.2e-69 fliJ N Flagellar biosynthesis chaperone
HMCIFNEL_02571 3.8e-36 ylxF S MgtE intracellular N domain
HMCIFNEL_02572 2.3e-220 fliK N Flagellar hook-length control protein
HMCIFNEL_02573 8.7e-72 flgD N Flagellar basal body rod modification protein
HMCIFNEL_02574 1.3e-137 flgG N Flagellar basal body rod
HMCIFNEL_02575 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HMCIFNEL_02576 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HMCIFNEL_02577 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HMCIFNEL_02578 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HMCIFNEL_02579 6e-96 fliZ N Flagellar biosynthesis protein, FliO
HMCIFNEL_02580 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HMCIFNEL_02581 6.4e-36 fliQ N Role in flagellar biosynthesis
HMCIFNEL_02582 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HMCIFNEL_02583 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HMCIFNEL_02584 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HMCIFNEL_02585 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
HMCIFNEL_02586 4.1e-156 flhG D Belongs to the ParA family
HMCIFNEL_02587 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HMCIFNEL_02588 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HMCIFNEL_02589 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HMCIFNEL_02590 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HMCIFNEL_02591 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HMCIFNEL_02592 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCIFNEL_02593 3.1e-76 ylxL
HMCIFNEL_02594 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HMCIFNEL_02595 8.2e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMCIFNEL_02596 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMCIFNEL_02597 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMCIFNEL_02598 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMCIFNEL_02599 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HMCIFNEL_02600 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HMCIFNEL_02601 7.7e-233 rasP M zinc metalloprotease
HMCIFNEL_02602 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMCIFNEL_02603 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMCIFNEL_02604 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HMCIFNEL_02605 1.1e-203 nusA K Participates in both transcription termination and antitermination
HMCIFNEL_02606 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HMCIFNEL_02607 3.1e-47 ylxQ J ribosomal protein
HMCIFNEL_02608 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMCIFNEL_02609 5e-44 ylxP S protein conserved in bacteria
HMCIFNEL_02610 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMCIFNEL_02611 7.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMCIFNEL_02612 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMCIFNEL_02613 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMCIFNEL_02614 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMCIFNEL_02615 2.2e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HMCIFNEL_02616 4.4e-233 pepR S Belongs to the peptidase M16 family
HMCIFNEL_02617 2.6e-42 ymxH S YlmC YmxH family
HMCIFNEL_02618 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HMCIFNEL_02619 1.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HMCIFNEL_02620 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMCIFNEL_02621 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HMCIFNEL_02622 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMCIFNEL_02623 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMCIFNEL_02624 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HMCIFNEL_02625 4.4e-32 S YlzJ-like protein
HMCIFNEL_02626 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMCIFNEL_02627 1.4e-133 ymfC K Transcriptional regulator
HMCIFNEL_02628 3.8e-205 ymfD EGP Major facilitator Superfamily
HMCIFNEL_02629 3.9e-232 ymfF S Peptidase M16
HMCIFNEL_02630 1.4e-242 ymfH S zinc protease
HMCIFNEL_02631 5e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HMCIFNEL_02632 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HMCIFNEL_02633 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HMCIFNEL_02634 2.1e-115 ymfM S protein conserved in bacteria
HMCIFNEL_02635 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMCIFNEL_02636 8.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
HMCIFNEL_02637 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMCIFNEL_02638 1.7e-213 pbpX V Beta-lactamase
HMCIFNEL_02639 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HMCIFNEL_02640 1.9e-152 ymdB S protein conserved in bacteria
HMCIFNEL_02641 1.2e-36 spoVS S Stage V sporulation protein S
HMCIFNEL_02642 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HMCIFNEL_02643 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HMCIFNEL_02644 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMCIFNEL_02645 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HMCIFNEL_02646 2.2e-88 cotE S Spore coat protein
HMCIFNEL_02647 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMCIFNEL_02648 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMCIFNEL_02649 2.2e-68 S Regulatory protein YrvL
HMCIFNEL_02650 1.1e-95 ymcC S Membrane
HMCIFNEL_02651 1.2e-103 pksA K Transcriptional regulator
HMCIFNEL_02652 4.4e-61 ymzB
HMCIFNEL_02653 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
HMCIFNEL_02654 1.2e-249 aprX O Belongs to the peptidase S8 family
HMCIFNEL_02655 1.9e-07 K Transcriptional regulator
HMCIFNEL_02656 2.1e-126 ymaC S Replication protein
HMCIFNEL_02657 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
HMCIFNEL_02658 6.2e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HMCIFNEL_02659 4.9e-51 ebrA P Small Multidrug Resistance protein
HMCIFNEL_02661 2.1e-46 ymaF S YmaF family
HMCIFNEL_02662 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMCIFNEL_02663 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HMCIFNEL_02664 8.2e-23
HMCIFNEL_02665 4.5e-22 ymzA
HMCIFNEL_02666 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HMCIFNEL_02667 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCIFNEL_02668 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMCIFNEL_02669 2e-109 ymaB
HMCIFNEL_02670 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMCIFNEL_02671 1.7e-176 spoVK O stage V sporulation protein K
HMCIFNEL_02672 4.7e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMCIFNEL_02673 9.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HMCIFNEL_02674 1.1e-68 glnR K transcriptional
HMCIFNEL_02675 1e-259 glnA 6.3.1.2 E glutamine synthetase
HMCIFNEL_02676 3.3e-113 tetR3 K Transcriptional regulator
HMCIFNEL_02677 1.9e-118 mepA V Multidrug transporter MatE
HMCIFNEL_02678 5.3e-70 mepA V Multidrug transporter MatE
HMCIFNEL_02679 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HMCIFNEL_02680 2.1e-111 yrkJ S membrane transporter protein
HMCIFNEL_02681 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HMCIFNEL_02682 9.3e-206 yrkH P Rhodanese Homology Domain
HMCIFNEL_02683 4.7e-16 perX S Sulfur reduction protein DsrE
HMCIFNEL_02684 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
HMCIFNEL_02685 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
HMCIFNEL_02686 7.8e-39 yrkD S protein conserved in bacteria
HMCIFNEL_02687 8.6e-21
HMCIFNEL_02688 1.8e-104 yrkC G Cupin domain
HMCIFNEL_02689 3.1e-150 bltR K helix_turn_helix, mercury resistance
HMCIFNEL_02690 3.5e-211 blt EGP Major facilitator Superfamily
HMCIFNEL_02691 1.5e-82 bltD 2.3.1.57 K FR47-like protein
HMCIFNEL_02692 1.1e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HMCIFNEL_02693 3.9e-16 S YrzO-like protein
HMCIFNEL_02694 1.9e-170 yrdR EG EamA-like transporter family
HMCIFNEL_02695 6.6e-159 yrdQ K Transcriptional regulator
HMCIFNEL_02696 3.6e-196 trkA P Oxidoreductase
HMCIFNEL_02697 2.6e-153 czcD P COG1230 Co Zn Cd efflux system component
HMCIFNEL_02698 4.2e-65 yodA S tautomerase
HMCIFNEL_02699 5e-162 gltR K LysR substrate binding domain
HMCIFNEL_02700 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
HMCIFNEL_02701 5.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HMCIFNEL_02702 2.2e-91 azlC E AzlC protein
HMCIFNEL_02703 1.1e-78 bkdR K helix_turn_helix ASNC type
HMCIFNEL_02704 9.7e-40 yrdF K ribonuclease inhibitor
HMCIFNEL_02705 2.1e-227 cypA C Cytochrome P450
HMCIFNEL_02706 4.2e-23 K Acetyltransferase (GNAT) family
HMCIFNEL_02707 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
HMCIFNEL_02708 1.9e-57 S Protein of unknown function (DUF2568)
HMCIFNEL_02710 6.4e-90 yrdA S DinB family
HMCIFNEL_02711 5.1e-164 aadK G Streptomycin adenylyltransferase
HMCIFNEL_02712 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HMCIFNEL_02713 3.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMCIFNEL_02714 4.8e-123 yrpD S Domain of unknown function, YrpD
HMCIFNEL_02716 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HMCIFNEL_02717 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_02718 1.7e-187 yrpG C Aldo/keto reductase family
HMCIFNEL_02719 9.5e-226 yraO C Citrate transporter
HMCIFNEL_02720 3.4e-163 yraN K Transcriptional regulator
HMCIFNEL_02721 5.9e-205 yraM S PrpF protein
HMCIFNEL_02722 1.1e-14 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HMCIFNEL_02723 3.2e-37 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMCIFNEL_02724 4.7e-151 S Alpha beta hydrolase
HMCIFNEL_02725 1.7e-60 T sh3 domain protein
HMCIFNEL_02726 3.4e-61 T sh3 domain protein
HMCIFNEL_02727 1.4e-65 E Glyoxalase-like domain
HMCIFNEL_02728 1.5e-36 yraG
HMCIFNEL_02729 1.9e-62 yraF M Spore coat protein
HMCIFNEL_02730 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HMCIFNEL_02731 7.5e-26 yraE
HMCIFNEL_02732 1.2e-12 yraD M Spore coat protein
HMCIFNEL_02734 1.4e-34 ydjO S Cold-inducible protein YdjO
HMCIFNEL_02735 8.4e-156 ydjP I Alpha/beta hydrolase family
HMCIFNEL_02736 6.7e-176 yeaA S Protein of unknown function (DUF4003)
HMCIFNEL_02737 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HMCIFNEL_02738 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HMCIFNEL_02739 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMCIFNEL_02740 9.5e-175 yeaC S COG0714 MoxR-like ATPases
HMCIFNEL_02741 2.9e-221 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HMCIFNEL_02742 0.0 yebA E COG1305 Transglutaminase-like enzymes
HMCIFNEL_02743 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMCIFNEL_02744 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_02745 9.8e-256 S Domain of unknown function (DUF4179)
HMCIFNEL_02746 1.5e-210 pbuG S permease
HMCIFNEL_02747 1.9e-115 yebC M Membrane
HMCIFNEL_02749 4e-93 yebE S UPF0316 protein
HMCIFNEL_02750 8e-28 yebG S NETI protein
HMCIFNEL_02751 7.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMCIFNEL_02752 1.6e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMCIFNEL_02753 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMCIFNEL_02754 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMCIFNEL_02755 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMCIFNEL_02756 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMCIFNEL_02757 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMCIFNEL_02758 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMCIFNEL_02759 7.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMCIFNEL_02760 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMCIFNEL_02761 1.7e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMCIFNEL_02762 4.5e-233 purD 6.3.4.13 F Belongs to the GARS family
HMCIFNEL_02763 8.2e-70 K helix_turn_helix ASNC type
HMCIFNEL_02764 3.5e-225 yjeH E Amino acid permease
HMCIFNEL_02765 2.7e-27 S Protein of unknown function (DUF2892)
HMCIFNEL_02766 0.0 yerA 3.5.4.2 F adenine deaminase
HMCIFNEL_02767 2e-188 yerB S Protein of unknown function (DUF3048) C-terminal domain
HMCIFNEL_02768 4.8e-51 yerC S protein conserved in bacteria
HMCIFNEL_02769 5.7e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HMCIFNEL_02770 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HMCIFNEL_02771 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMCIFNEL_02772 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMCIFNEL_02773 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HMCIFNEL_02774 1.3e-72 L Integrase core domain
HMCIFNEL_02775 2.4e-60 ykzC S Acetyltransferase (GNAT) family
HMCIFNEL_02776 8.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
HMCIFNEL_02777 7.2e-26 ykzI
HMCIFNEL_02778 2.1e-117 yktB S Belongs to the UPF0637 family
HMCIFNEL_02779 1.6e-42 yktA S Belongs to the UPF0223 family
HMCIFNEL_02780 1e-276 speA 4.1.1.19 E Arginine
HMCIFNEL_02781 2.7e-10 S SR1 protein
HMCIFNEL_02782 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HMCIFNEL_02783 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMCIFNEL_02784 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMCIFNEL_02785 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMCIFNEL_02786 2.2e-191 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMCIFNEL_02787 2e-115 recN L Putative cell-wall binding lipoprotein
HMCIFNEL_02789 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMCIFNEL_02790 1e-145 ykrA S hydrolases of the HAD superfamily
HMCIFNEL_02791 8.2e-31 ykzG S Belongs to the UPF0356 family
HMCIFNEL_02792 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMCIFNEL_02793 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HMCIFNEL_02794 1.5e-115 ktrA P COG0569 K transport systems, NAD-binding component
HMCIFNEL_02795 1.2e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HMCIFNEL_02796 1.3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HMCIFNEL_02797 1.5e-43 abrB K of stationary sporulation gene expression
HMCIFNEL_02798 7.7e-183 mreB D Rod-share determining protein MreBH
HMCIFNEL_02799 1.1e-12 S Uncharacterized protein YkpC
HMCIFNEL_02800 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HMCIFNEL_02801 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMCIFNEL_02802 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMCIFNEL_02803 1.1e-38 ykoA
HMCIFNEL_02804 2.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HMCIFNEL_02805 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HMCIFNEL_02806 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HMCIFNEL_02807 3.1e-136 fruR K Transcriptional regulator
HMCIFNEL_02808 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HMCIFNEL_02809 7.2e-124 macB V ABC transporter, ATP-binding protein
HMCIFNEL_02810 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMCIFNEL_02811 1e-117 yknW S Yip1 domain
HMCIFNEL_02812 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMCIFNEL_02813 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMCIFNEL_02814 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HMCIFNEL_02815 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HMCIFNEL_02816 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HMCIFNEL_02817 5.2e-245 moeA 2.10.1.1 H molybdopterin
HMCIFNEL_02818 2.2e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HMCIFNEL_02819 2.5e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HMCIFNEL_02820 1.2e-145 yknT
HMCIFNEL_02821 1.3e-72 L Integrase core domain
HMCIFNEL_02822 4.8e-108 yodC C nitroreductase
HMCIFNEL_02823 4.4e-55 yodB K transcriptional
HMCIFNEL_02824 1.4e-63 yodA S tautomerase
HMCIFNEL_02825 1.2e-204 gntP EG COG2610 H gluconate symporter and related permeases
HMCIFNEL_02826 2e-09
HMCIFNEL_02827 1.5e-64 yozR S COG0071 Molecular chaperone (small heat shock protein)
HMCIFNEL_02828 1.2e-160 rarD S -transporter
HMCIFNEL_02829 1.5e-43
HMCIFNEL_02830 2.2e-60 yojF S Protein of unknown function (DUF1806)
HMCIFNEL_02831 2.1e-125 yojG S deacetylase
HMCIFNEL_02832 1.6e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMCIFNEL_02833 2.2e-241 norM V Multidrug efflux pump
HMCIFNEL_02835 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMCIFNEL_02836 1e-229 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HMCIFNEL_02837 6.2e-195 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HMCIFNEL_02838 5.6e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HMCIFNEL_02839 2.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
HMCIFNEL_02840 0.0 yojO P Von Willebrand factor
HMCIFNEL_02841 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HMCIFNEL_02842 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HMCIFNEL_02843 8.6e-168 yocS S -transporter
HMCIFNEL_02844 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMCIFNEL_02845 2.3e-164 sodA 1.15.1.1 P Superoxide dismutase
HMCIFNEL_02846 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HMCIFNEL_02847 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HMCIFNEL_02848 2.7e-31 yozC
HMCIFNEL_02849 4.2e-56 yozO S Bacterial PH domain
HMCIFNEL_02850 1.9e-36 yocN
HMCIFNEL_02851 1.1e-40 yozN
HMCIFNEL_02852 5.9e-85 yocM O Belongs to the small heat shock protein (HSP20) family
HMCIFNEL_02853 1.7e-29
HMCIFNEL_02854 8.4e-54 yocL
HMCIFNEL_02855 3.3e-83 dksA T general stress protein
HMCIFNEL_02856 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMCIFNEL_02857 0.0 recQ 3.6.4.12 L DNA helicase
HMCIFNEL_02858 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HMCIFNEL_02859 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMCIFNEL_02860 1.7e-196 desK 2.7.13.3 T Histidine kinase
HMCIFNEL_02861 5.3e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HMCIFNEL_02862 1.8e-184 yocD 3.4.17.13 V peptidase S66
HMCIFNEL_02863 1.5e-91 yocC
HMCIFNEL_02864 5.1e-142
HMCIFNEL_02865 1.5e-92 yozB S membrane
HMCIFNEL_02867 3.5e-96 L Transposase
HMCIFNEL_02868 1.3e-72 L Integrase core domain
HMCIFNEL_02869 7.2e-152 ydjN U Involved in the tonB-independent uptake of proteins
HMCIFNEL_02870 4.5e-64 ydjM M Lytic transglycolase
HMCIFNEL_02871 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HMCIFNEL_02872 5e-257 iolT EGP Major facilitator Superfamily
HMCIFNEL_02873 5.3e-27 S Ion transport 2 domain protein
HMCIFNEL_02874 4.9e-145 S Ion transport 2 domain protein
HMCIFNEL_02875 8.5e-147 ydjI S virion core protein (lumpy skin disease virus)
HMCIFNEL_02876 2.5e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HMCIFNEL_02877 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMCIFNEL_02878 1.9e-113 pspA KT Phage shock protein A
HMCIFNEL_02879 1.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HMCIFNEL_02880 2.1e-252 gutA G MFS/sugar transport protein
HMCIFNEL_02881 1.5e-200 gutB 1.1.1.14 E Dehydrogenase
HMCIFNEL_02882 1.5e-97 K NB-ARC domain
HMCIFNEL_02883 0.0 K NB-ARC domain
HMCIFNEL_02884 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HMCIFNEL_02885 3.2e-100 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HMCIFNEL_02886 5.2e-287 hsdM 2.1.1.72 V Type I restriction-modification system
HMCIFNEL_02887 3.1e-80 3.1.21.3 V Type I restriction modification DNA specificity domain
HMCIFNEL_02888 5.1e-64 yozB S Membrane
HMCIFNEL_02891 6.1e-98 M nucleic acid phosphodiester bond hydrolysis
HMCIFNEL_02892 1e-151 yobL S Bacterial EndoU nuclease
HMCIFNEL_02893 4.1e-40
HMCIFNEL_02895 8.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMCIFNEL_02896 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMCIFNEL_02897 7.9e-129 ydiL S CAAX protease self-immunity
HMCIFNEL_02898 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HMCIFNEL_02899 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMCIFNEL_02900 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HMCIFNEL_02901 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMCIFNEL_02902 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HMCIFNEL_02903 0.0 ydiF S ABC transporter
HMCIFNEL_02904 3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMCIFNEL_02905 2.8e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMCIFNEL_02906 1.6e-123 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HMCIFNEL_02907 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HMCIFNEL_02908 1.2e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HMCIFNEL_02910 7.8e-08
HMCIFNEL_02911 5.8e-95 rok K Repressor of ComK
HMCIFNEL_02912 1.4e-80 ykuV CO thiol-disulfide
HMCIFNEL_02913 1.1e-100 ykuU O Alkyl hydroperoxide reductase
HMCIFNEL_02914 8.8e-142 ykuT M Mechanosensitive ion channel
HMCIFNEL_02915 9e-37 ykuS S Belongs to the UPF0180 family
HMCIFNEL_02916 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMCIFNEL_02917 2.4e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMCIFNEL_02918 5.1e-78 fld C Flavodoxin
HMCIFNEL_02919 9.7e-174 ykuO
HMCIFNEL_02920 1e-84 fld C Flavodoxin domain
HMCIFNEL_02921 3.5e-168 ccpC K Transcriptional regulator
HMCIFNEL_02922 1.6e-76 ykuL S CBS domain
HMCIFNEL_02923 3.9e-27 ykzF S Antirepressor AbbA
HMCIFNEL_02924 1.3e-93 ykuK S Ribonuclease H-like
HMCIFNEL_02925 3.9e-37 ykuJ S protein conserved in bacteria
HMCIFNEL_02927 3.3e-233 ykuI T Diguanylate phosphodiesterase
HMCIFNEL_02929 0.0 3.2.1.132 M Putative peptidoglycan binding domain
HMCIFNEL_02930 6.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_02931 1.6e-165 ykuE S Metallophosphoesterase
HMCIFNEL_02932 1.5e-86 ykuD S protein conserved in bacteria
HMCIFNEL_02933 4.8e-238 ykuC EGP Major facilitator Superfamily
HMCIFNEL_02934 1.7e-84 ykyB S YkyB-like protein
HMCIFNEL_02935 2.4e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
HMCIFNEL_02936 2.2e-15
HMCIFNEL_02937 3.7e-221 patA 2.6.1.1 E Aminotransferase
HMCIFNEL_02938 0.0 pilS 2.7.13.3 T Histidine kinase
HMCIFNEL_02939 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HMCIFNEL_02940 7.5e-108 ykwD J protein with SCP PR1 domains
HMCIFNEL_02941 5.8e-87
HMCIFNEL_02942 7.8e-94
HMCIFNEL_02943 3.1e-254
HMCIFNEL_02944 2.7e-280
HMCIFNEL_02945 0.0 gp17a S Terminase-like family
HMCIFNEL_02946 2.2e-173
HMCIFNEL_02950 2.1e-203 S Calcineurin-like phosphoesterase superfamily domain
HMCIFNEL_02952 1.1e-33 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMCIFNEL_02953 2.6e-94
HMCIFNEL_02954 1.6e-14 L GIY-YIG type nucleases (URI domain)
HMCIFNEL_02955 0.0 S RNA-directed RNA polymerase activity
HMCIFNEL_02958 1.6e-235
HMCIFNEL_02960 2e-198 3.1.21.3 L Domain of unknown function (DUF4942)
HMCIFNEL_02967 1.7e-08
HMCIFNEL_02970 9.5e-17
HMCIFNEL_02971 4.8e-12 S AAA domain
HMCIFNEL_02978 2.2e-154
HMCIFNEL_02980 3.2e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HMCIFNEL_02987 5.4e-92 S Protein of unknown function (DUF1273)
HMCIFNEL_02991 2.9e-16 3.1.3.16, 3.1.4.37 T AAA domain
HMCIFNEL_02992 1.9e-53 S dUTPase
HMCIFNEL_02993 3.4e-22
HMCIFNEL_02997 1.1e-33 K Transcriptional regulator
HMCIFNEL_02998 2.1e-177
HMCIFNEL_02999 1.6e-260 S DNA-sulfur modification-associated
HMCIFNEL_03000 2.6e-197 L Belongs to the 'phage' integrase family
HMCIFNEL_03005 8.6e-106
HMCIFNEL_03007 5.8e-32 yoaF
HMCIFNEL_03008 7.7e-10
HMCIFNEL_03009 3.8e-36
HMCIFNEL_03010 2.1e-49 FG Scavenger mRNA decapping enzyme C-term binding
HMCIFNEL_03015 1e-74
HMCIFNEL_03016 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HMCIFNEL_03017 4.4e-259 mcpC NT chemotaxis protein
HMCIFNEL_03018 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMCIFNEL_03019 1.4e-200 splB 4.1.99.14 L Spore photoproduct lyase
HMCIFNEL_03020 7.2e-39 splA S Transcriptional regulator
HMCIFNEL_03021 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMCIFNEL_03022 2.1e-39 ptsH G phosphocarrier protein HPr
HMCIFNEL_03023 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMCIFNEL_03024 7.6e-128 glcT K antiterminator
HMCIFNEL_03026 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
HMCIFNEL_03027 1.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HMCIFNEL_03028 2.3e-09
HMCIFNEL_03029 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HMCIFNEL_03030 1.6e-88 stoA CO thiol-disulfide
HMCIFNEL_03031 2.2e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMCIFNEL_03032 4.8e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HMCIFNEL_03033 2.8e-28
HMCIFNEL_03034 6e-25 ykvS S protein conserved in bacteria
HMCIFNEL_03035 2.8e-45 ykvR S Protein of unknown function (DUF3219)
HMCIFNEL_03036 8.3e-34 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HMCIFNEL_03037 1.5e-89 L Belongs to the 'phage' integrase family
HMCIFNEL_03038 2.4e-41
HMCIFNEL_03039 1.2e-247 I Pfam Lipase (class 3)
HMCIFNEL_03040 3e-28 S Protein of unknown function (DUF1433)
HMCIFNEL_03041 7.1e-46 S Protein of unknown function (DUF1433)
HMCIFNEL_03042 2.8e-20 M Pectate lyase superfamily protein
HMCIFNEL_03043 3.7e-119
HMCIFNEL_03044 1.6e-293 S Pfam Transposase IS66
HMCIFNEL_03045 8.5e-86 S Phage tail protein
HMCIFNEL_03046 0.0 S peptidoglycan catabolic process
HMCIFNEL_03047 5.4e-46
HMCIFNEL_03049 8.3e-190 xerH A Belongs to the 'phage' integrase family
HMCIFNEL_03050 1.2e-52
HMCIFNEL_03051 5.9e-56
HMCIFNEL_03052 3.3e-99 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HMCIFNEL_03053 5.4e-08 S Phage uncharacterised protein (Phage_XkdX)
HMCIFNEL_03054 5.9e-11
HMCIFNEL_03055 9.5e-18
HMCIFNEL_03056 1.2e-45
HMCIFNEL_03059 3.2e-59
HMCIFNEL_03060 2.3e-72
HMCIFNEL_03061 1.7e-77
HMCIFNEL_03062 1.4e-121
HMCIFNEL_03064 3.2e-68
HMCIFNEL_03065 1.1e-80
HMCIFNEL_03066 6.9e-90
HMCIFNEL_03067 3.5e-96 L Transposase
HMCIFNEL_03068 1.7e-159 ytbE S reductase
HMCIFNEL_03069 3.3e-201 ytbD EGP Major facilitator Superfamily
HMCIFNEL_03070 6.5e-15 ytcD K Transcriptional regulator
HMCIFNEL_03071 2.8e-41 ytcD K Transcriptional regulator
HMCIFNEL_03072 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMCIFNEL_03073 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HMCIFNEL_03074 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMCIFNEL_03075 7.7e-266 dnaB L Membrane attachment protein
HMCIFNEL_03076 3e-173 dnaI L Primosomal protein DnaI
HMCIFNEL_03077 1.6e-109 ytxB S SNARE associated Golgi protein
HMCIFNEL_03078 1.6e-157 ytxC S YtxC-like family
HMCIFNEL_03080 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMCIFNEL_03081 5.2e-147 ysaA S HAD-hyrolase-like
HMCIFNEL_03082 0.0 lytS 2.7.13.3 T Histidine kinase
HMCIFNEL_03083 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HMCIFNEL_03084 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HMCIFNEL_03085 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HMCIFNEL_03087 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMCIFNEL_03088 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMCIFNEL_03089 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMCIFNEL_03090 7.5e-45 ysdA S Membrane
HMCIFNEL_03091 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HMCIFNEL_03092 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HMCIFNEL_03093 4e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HMCIFNEL_03094 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HMCIFNEL_03095 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HMCIFNEL_03096 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HMCIFNEL_03097 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HMCIFNEL_03098 3.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HMCIFNEL_03099 5.8e-252 araN G carbohydrate transport
HMCIFNEL_03100 4.2e-167 araP G carbohydrate transport
HMCIFNEL_03101 9.9e-144 araQ G transport system permease
HMCIFNEL_03102 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HMCIFNEL_03103 0.0 cstA T Carbon starvation protein
HMCIFNEL_03105 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HMCIFNEL_03106 8.3e-254 glcF C Glycolate oxidase
HMCIFNEL_03107 3.1e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
HMCIFNEL_03108 5.9e-205 ysfB KT regulator
HMCIFNEL_03109 2.6e-32 sspI S Belongs to the SspI family
HMCIFNEL_03110 1.1e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMCIFNEL_03111 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMCIFNEL_03112 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMCIFNEL_03113 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMCIFNEL_03114 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMCIFNEL_03115 1.7e-85 cvpA S membrane protein, required for colicin V production
HMCIFNEL_03116 0.0 polX L COG1796 DNA polymerase IV (family X)
HMCIFNEL_03117 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMCIFNEL_03118 7.3e-68 yshE S membrane
HMCIFNEL_03119 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HMCIFNEL_03120 4e-99 fadR K Transcriptional regulator
HMCIFNEL_03121 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HMCIFNEL_03122 3.8e-134 etfB C Electron transfer flavoprotein
HMCIFNEL_03123 5.1e-176 etfA C Electron transfer flavoprotein
HMCIFNEL_03125 4.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HMCIFNEL_03126 2e-52 trxA O Belongs to the thioredoxin family
HMCIFNEL_03127 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMCIFNEL_03128 2.7e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HMCIFNEL_03129 1.2e-79 yslB S Protein of unknown function (DUF2507)
HMCIFNEL_03130 2.4e-107 sdhC C succinate dehydrogenase
HMCIFNEL_03131 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HMCIFNEL_03132 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HMCIFNEL_03133 2.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HMCIFNEL_03134 3.3e-30 gerE K Transcriptional regulator
HMCIFNEL_03135 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HMCIFNEL_03136 3.9e-153 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMCIFNEL_03137 2.9e-196 gerM S COG5401 Spore germination protein
HMCIFNEL_03138 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HMCIFNEL_03139 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMCIFNEL_03140 4.1e-92 ysnB S Phosphoesterase
HMCIFNEL_03142 3.8e-132 ysnF S protein conserved in bacteria
HMCIFNEL_03143 1.8e-78 ysnE K acetyltransferase
HMCIFNEL_03145 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HMCIFNEL_03146 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HMCIFNEL_03147 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMCIFNEL_03148 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMCIFNEL_03149 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMCIFNEL_03150 1.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMCIFNEL_03151 2.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMCIFNEL_03152 5.1e-187 ysoA H Tetratricopeptide repeat
HMCIFNEL_03153 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMCIFNEL_03154 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMCIFNEL_03155 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HMCIFNEL_03156 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HMCIFNEL_03157 5.7e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HMCIFNEL_03158 1.4e-89 ysxD
HMCIFNEL_03159 4.6e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HMCIFNEL_03160 3.6e-146 hemX O cytochrome C
HMCIFNEL_03161 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HMCIFNEL_03162 1.3e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HMCIFNEL_03163 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HMCIFNEL_03164 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HMCIFNEL_03165 1.1e-211 spoVID M stage VI sporulation protein D
HMCIFNEL_03166 5e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HMCIFNEL_03167 1.6e-25
HMCIFNEL_03168 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMCIFNEL_03169 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMCIFNEL_03170 2.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HMCIFNEL_03171 2.3e-163 spoIIB S Sporulation related domain
HMCIFNEL_03172 2.8e-102 maf D septum formation protein Maf
HMCIFNEL_03173 5.9e-126 radC E Belongs to the UPF0758 family
HMCIFNEL_03174 1.8e-184 mreB D Rod shape-determining protein MreB
HMCIFNEL_03175 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HMCIFNEL_03176 1.4e-84 mreD M shape-determining protein
HMCIFNEL_03177 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMCIFNEL_03178 4.7e-143 minD D Belongs to the ParA family
HMCIFNEL_03179 1.1e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HMCIFNEL_03180 2e-160 spoIVFB S Stage IV sporulation protein
HMCIFNEL_03181 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMCIFNEL_03182 4.1e-56 ysxB J ribosomal protein
HMCIFNEL_03183 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMCIFNEL_03184 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HMCIFNEL_03185 4.3e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMCIFNEL_03186 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HMCIFNEL_03187 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HMCIFNEL_03188 2.3e-93 niaR S small molecule binding protein (contains 3H domain)
HMCIFNEL_03189 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
HMCIFNEL_03190 3.2e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HMCIFNEL_03191 3.4e-155 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HMCIFNEL_03192 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HMCIFNEL_03193 2.6e-134 safA M spore coat assembly protein SafA
HMCIFNEL_03194 6e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMCIFNEL_03195 6.1e-126 yebC K transcriptional regulatory protein
HMCIFNEL_03196 4.5e-261 alsT E Sodium alanine symporter
HMCIFNEL_03197 4e-51 S Family of unknown function (DUF5412)
HMCIFNEL_03199 6.5e-119 yrzF T serine threonine protein kinase
HMCIFNEL_03200 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HMCIFNEL_03201 5.3e-253 csbX EGP Major facilitator Superfamily
HMCIFNEL_03202 4.8e-93 bofC S BofC C-terminal domain
HMCIFNEL_03203 4.5e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMCIFNEL_03204 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMCIFNEL_03205 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HMCIFNEL_03206 5.7e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMCIFNEL_03207 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMCIFNEL_03208 8e-39 yajC U Preprotein translocase subunit YajC
HMCIFNEL_03209 3.8e-73 yrzE S Protein of unknown function (DUF3792)
HMCIFNEL_03210 6.6e-111 yrbG S membrane
HMCIFNEL_03211 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMCIFNEL_03212 9.4e-49 yrzD S Post-transcriptional regulator
HMCIFNEL_03213 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HMCIFNEL_03214 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HMCIFNEL_03215 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HMCIFNEL_03216 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMCIFNEL_03217 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMCIFNEL_03218 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMCIFNEL_03219 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMCIFNEL_03220 1.1e-260 lytH 3.5.1.28 M COG3103 SH3 domain protein
HMCIFNEL_03222 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMCIFNEL_03223 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HMCIFNEL_03224 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HMCIFNEL_03225 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HMCIFNEL_03226 1.2e-70 cymR K Transcriptional regulator
HMCIFNEL_03227 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
HMCIFNEL_03228 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMCIFNEL_03229 1.4e-15 S COG0457 FOG TPR repeat
HMCIFNEL_03230 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMCIFNEL_03231 6.6e-81 yrrD S protein conserved in bacteria
HMCIFNEL_03232 9.8e-31 yrzR
HMCIFNEL_03233 8e-08 S Protein of unknown function (DUF3918)
HMCIFNEL_03234 7.6e-107 glnP P ABC transporter
HMCIFNEL_03235 2.3e-108 gluC P ABC transporter
HMCIFNEL_03236 2.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
HMCIFNEL_03237 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HMCIFNEL_03238 2.5e-168 yrrI S AI-2E family transporter
HMCIFNEL_03239 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMCIFNEL_03240 1.7e-41 yrzL S Belongs to the UPF0297 family
HMCIFNEL_03241 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMCIFNEL_03242 1.2e-45 yrzB S Belongs to the UPF0473 family
HMCIFNEL_03243 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMCIFNEL_03244 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
HMCIFNEL_03245 7.8e-174 yegQ O Peptidase U32
HMCIFNEL_03246 1.4e-245 yegQ O COG0826 Collagenase and related proteases
HMCIFNEL_03247 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HMCIFNEL_03248 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMCIFNEL_03249 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HMCIFNEL_03250 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HMCIFNEL_03251 3.5e-26 yrzA S Protein of unknown function (DUF2536)
HMCIFNEL_03252 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HMCIFNEL_03253 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMCIFNEL_03254 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HMCIFNEL_03255 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMCIFNEL_03256 4.6e-35 yrhC S YrhC-like protein
HMCIFNEL_03257 7.1e-78 yrhD S Protein of unknown function (DUF1641)
HMCIFNEL_03258 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HMCIFNEL_03259 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HMCIFNEL_03261 3e-142 focA P Formate nitrite
HMCIFNEL_03264 1e-93 yrhH Q methyltransferase
HMCIFNEL_03265 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HMCIFNEL_03266 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HMCIFNEL_03267 9e-44 yrhK S YrhK-like protein
HMCIFNEL_03268 0.0 yrhL I Acyltransferase family
HMCIFNEL_03269 7.2e-150 rsiV S Protein of unknown function (DUF3298)
HMCIFNEL_03270 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_03271 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HMCIFNEL_03272 3.1e-105 yrhP E LysE type translocator
HMCIFNEL_03273 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HMCIFNEL_03274 0.0 levR K PTS system fructose IIA component
HMCIFNEL_03275 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HMCIFNEL_03276 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HMCIFNEL_03277 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HMCIFNEL_03278 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HMCIFNEL_03279 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HMCIFNEL_03280 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HMCIFNEL_03281 2.4e-195 adhA 1.1.1.1 C alcohol dehydrogenase
HMCIFNEL_03282 4.4e-47 yraB K helix_turn_helix, mercury resistance
HMCIFNEL_03283 1.1e-22 yraD M Spore coat protein
HMCIFNEL_03284 2.4e-195 yetN S Protein of unknown function (DUF3900)
HMCIFNEL_03285 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HMCIFNEL_03286 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMCIFNEL_03287 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HMCIFNEL_03288 1.9e-172 yfnG 4.2.1.45 M dehydratase
HMCIFNEL_03289 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
HMCIFNEL_03290 2.6e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HMCIFNEL_03291 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
HMCIFNEL_03292 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HMCIFNEL_03293 6.2e-90 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMCIFNEL_03294 2.4e-240 yfnA E amino acid
HMCIFNEL_03295 2.6e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMCIFNEL_03296 4.6e-112 yfmS NT chemotaxis protein
HMCIFNEL_03297 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMCIFNEL_03298 2e-74 yfmQ S Uncharacterised protein from bacillus cereus group
HMCIFNEL_03299 1.4e-69 yfmP K transcriptional
HMCIFNEL_03300 1.5e-209 yfmO EGP Major facilitator Superfamily
HMCIFNEL_03301 1.3e-72 L Integrase core domain
HMCIFNEL_03302 9.2e-92 batE T Bacterial SH3 domain homologues
HMCIFNEL_03303 3.9e-50 yfhL S SdpI/YhfL protein family
HMCIFNEL_03304 1.3e-170 yfhM S Alpha beta hydrolase
HMCIFNEL_03305 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMCIFNEL_03306 0.0 yfhO S Bacterial membrane protein YfhO
HMCIFNEL_03307 2.1e-185 yfhP S membrane-bound metal-dependent
HMCIFNEL_03308 2.5e-210 mutY L A G-specific
HMCIFNEL_03309 6.9e-36 yfhS
HMCIFNEL_03310 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_03311 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
HMCIFNEL_03312 1.5e-37 ygaB S YgaB-like protein
HMCIFNEL_03313 1.3e-104 ygaC J Belongs to the UPF0374 family
HMCIFNEL_03314 1.8e-301 ygaD V ABC transporter
HMCIFNEL_03315 3.6e-178 ygaE S Membrane
HMCIFNEL_03316 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HMCIFNEL_03317 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HMCIFNEL_03318 4e-80 perR P Belongs to the Fur family
HMCIFNEL_03319 9.5e-56 ygzB S UPF0295 protein
HMCIFNEL_03320 2.5e-166 ygxA S Nucleotidyltransferase-like
HMCIFNEL_03321 1.4e-107 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HMCIFNEL_03322 2.2e-80 yokK S SMI1 / KNR4 family
HMCIFNEL_03323 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
HMCIFNEL_03324 3.8e-291 UW nuclease activity
HMCIFNEL_03325 1.1e-101 yokH G SMI1 / KNR4 family
HMCIFNEL_03326 1.1e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HMCIFNEL_03327 1e-198 yobO M Pectate lyase superfamily protein
HMCIFNEL_03328 2.4e-221 yobO M Pectate lyase superfamily protein
HMCIFNEL_03329 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HMCIFNEL_03330 1.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
HMCIFNEL_03331 8.5e-139 yobR 2.3.1.1 J FR47-like protein
HMCIFNEL_03332 2.8e-97 yobS K Transcriptional regulator
HMCIFNEL_03333 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HMCIFNEL_03334 3.1e-86 yobU K Bacterial transcription activator, effector binding domain
HMCIFNEL_03335 2.7e-174 yobV K WYL domain
HMCIFNEL_03336 2.6e-92 yobW
HMCIFNEL_03337 1e-51 czrA K transcriptional
HMCIFNEL_03338 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HMCIFNEL_03341 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HMCIFNEL_03342 4.9e-12
HMCIFNEL_03343 1.1e-127 yydK K Transcriptional regulator
HMCIFNEL_03344 3.7e-32 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HMCIFNEL_03345 3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMCIFNEL_03346 2.5e-286 ahpF O Alkyl hydroperoxide reductase
HMCIFNEL_03347 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HMCIFNEL_03348 2.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMCIFNEL_03349 5.9e-231 gntP EG COG2610 H gluconate symporter and related permeases
HMCIFNEL_03350 1.2e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HMCIFNEL_03351 7.3e-127 gntR K transcriptional
HMCIFNEL_03352 1.2e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMCIFNEL_03353 7.4e-186 yxaB GM Polysaccharide pyruvyl transferase
HMCIFNEL_03354 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HMCIFNEL_03355 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HMCIFNEL_03356 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMCIFNEL_03357 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMCIFNEL_03358 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMCIFNEL_03359 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMCIFNEL_03360 1.4e-95 yaaI Q COG1335 Amidases related to nicotinamidase
HMCIFNEL_03361 5.1e-208 yaaH M Glycoside Hydrolase Family
HMCIFNEL_03362 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HMCIFNEL_03363 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HMCIFNEL_03364 1.3e-09
HMCIFNEL_03365 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMCIFNEL_03366 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HMCIFNEL_03367 2.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HMCIFNEL_03368 7.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMCIFNEL_03369 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HMCIFNEL_03370 4.8e-179 yaaC S YaaC-like Protein
HMCIFNEL_03371 3.5e-96 L Transposase
HMCIFNEL_03373 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMCIFNEL_03374 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HMCIFNEL_03375 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HMCIFNEL_03376 3e-137 rsbR T Positive regulator of sigma-B
HMCIFNEL_03377 5.2e-57 rsbS T antagonist
HMCIFNEL_03378 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HMCIFNEL_03379 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HMCIFNEL_03380 3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
HMCIFNEL_03381 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HMCIFNEL_03382 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCIFNEL_03383 1.4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HMCIFNEL_03384 0.0 yhgF K COG2183 Transcriptional accessory protein
HMCIFNEL_03392 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
HMCIFNEL_03393 1.3e-72 L Integrase core domain
HMCIFNEL_03394 2.4e-29 KLT Protein tyrosine kinase
HMCIFNEL_03395 4.3e-11 S YolD-like protein
HMCIFNEL_03396 1.9e-36
HMCIFNEL_03397 9e-19
HMCIFNEL_03398 5.1e-18
HMCIFNEL_03399 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
HMCIFNEL_03400 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
HMCIFNEL_03402 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HMCIFNEL_03403 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HMCIFNEL_03404 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMCIFNEL_03405 4.8e-51 yjdF S Protein of unknown function (DUF2992)
HMCIFNEL_03406 1.1e-89 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCIFNEL_03407 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCIFNEL_03408 2.2e-91 yuaB
HMCIFNEL_03409 5.5e-95 yuaC K Belongs to the GbsR family
HMCIFNEL_03410 1.2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HMCIFNEL_03411 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HMCIFNEL_03412 4.8e-105 yuaD
HMCIFNEL_03413 3.3e-83 yuaE S DinB superfamily
HMCIFNEL_03414 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HMCIFNEL_03415 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
HMCIFNEL_03416 3.4e-94 M1-753 M FR47-like protein
HMCIFNEL_03417 5.7e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HMCIFNEL_03419 3.6e-66 K Transcriptional regulator
HMCIFNEL_03420 8e-218 pre D plasmid recombination enzyme
HMCIFNEL_03421 1.3e-21
HMCIFNEL_03423 3.8e-42
HMCIFNEL_03424 1.4e-195 L Replication protein
HMCIFNEL_03425 5.5e-97 S Tetratricopeptide repeat
HMCIFNEL_03426 2.4e-87
HMCIFNEL_03427 1.6e-186 3.5.1.28 M Ami_2
HMCIFNEL_03428 4.4e-32 bhlA S BhlA holin family
HMCIFNEL_03429 5.5e-40 S SPP1 phage holin
HMCIFNEL_03430 3.4e-74 O protein disulfide oxidoreductase activity
HMCIFNEL_03431 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMCIFNEL_03432 1.2e-70 CO cell redox homeostasis
HMCIFNEL_03433 4.2e-292 V Peptidase C39 family
HMCIFNEL_03434 6.5e-78 V Peptidase C39 family
HMCIFNEL_03437 1.9e-236 S impB/mucB/samB family C-terminal domain
HMCIFNEL_03438 4.6e-52 S YolD-like protein
HMCIFNEL_03439 1.3e-40
HMCIFNEL_03441 4e-09 S Domain of unknown function (DUF4879)
HMCIFNEL_03443 1.3e-96 J Acetyltransferase (GNAT) domain
HMCIFNEL_03444 1.2e-94 yokK S SMI1 / KNR4 family
HMCIFNEL_03445 2.3e-78 S SMI1-KNR4 cell-wall
HMCIFNEL_03446 6.7e-86 S SMI1-KNR4 cell-wall
HMCIFNEL_03447 8.8e-307 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HMCIFNEL_03448 1.5e-65 G SMI1-KNR4 cell-wall
HMCIFNEL_03449 4.6e-36
HMCIFNEL_03450 1.5e-105 yokF 3.1.31.1 L RNA catabolic process
HMCIFNEL_03451 2.6e-54 S DNase/tRNase domain of colicin-like bacteriocin
HMCIFNEL_03452 7.1e-65 S SMI1 / KNR4 family
HMCIFNEL_03454 4.9e-240 yokA L Recombinase
HMCIFNEL_03455 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
HMCIFNEL_03456 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMCIFNEL_03457 3.9e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMCIFNEL_03458 1.6e-70 ypoP K transcriptional
HMCIFNEL_03459 1.9e-221 mepA V MATE efflux family protein
HMCIFNEL_03460 1.2e-28 ypmT S Uncharacterized ympT
HMCIFNEL_03461 1.1e-98 ypmS S protein conserved in bacteria
HMCIFNEL_03462 1.1e-136 ypmR E GDSL-like Lipase/Acylhydrolase
HMCIFNEL_03463 1.3e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HMCIFNEL_03464 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HMCIFNEL_03465 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMCIFNEL_03466 6.8e-184 pspF K Transcriptional regulator
HMCIFNEL_03467 4.2e-110 hlyIII S protein, Hemolysin III
HMCIFNEL_03468 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HMCIFNEL_03469 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMCIFNEL_03470 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMCIFNEL_03471 3.6e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HMCIFNEL_03472 5.5e-104 ypjP S YpjP-like protein
HMCIFNEL_03473 6.5e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HMCIFNEL_03474 1.7e-75 yphP S Belongs to the UPF0403 family
HMCIFNEL_03475 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMCIFNEL_03476 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HMCIFNEL_03477 6.7e-58 ypgQ S phosphohydrolase
HMCIFNEL_03478 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HMCIFNEL_03479 1.2e-174 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMCIFNEL_03480 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HMCIFNEL_03481 1e-30 cspD K Cold-shock protein
HMCIFNEL_03482 3.8e-16 degR
HMCIFNEL_03483 8.1e-31 S Protein of unknown function (DUF2564)
HMCIFNEL_03484 3e-29 ypeQ S Zinc-finger
HMCIFNEL_03485 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HMCIFNEL_03486 2.8e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HMCIFNEL_03487 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HMCIFNEL_03489 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HMCIFNEL_03490 2e-07
HMCIFNEL_03491 2.9e-38 ypbS S Protein of unknown function (DUF2533)
HMCIFNEL_03492 0.0 ypbR S Dynamin family
HMCIFNEL_03494 6.7e-87 ypbQ S protein conserved in bacteria
HMCIFNEL_03495 6.3e-207 bcsA Q Naringenin-chalcone synthase
HMCIFNEL_03496 2.9e-227 pbuX F xanthine
HMCIFNEL_03497 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMCIFNEL_03498 2.7e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HMCIFNEL_03499 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HMCIFNEL_03500 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HMCIFNEL_03501 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HMCIFNEL_03502 3.3e-186 ptxS K transcriptional
HMCIFNEL_03503 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HMCIFNEL_03504 5e-120 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_03505 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HMCIFNEL_03507 9.2e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMCIFNEL_03508 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMCIFNEL_03509 5.3e-90 ypsA S Belongs to the UPF0398 family
HMCIFNEL_03510 1.9e-236 yprB L RNase_H superfamily
HMCIFNEL_03511 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HMCIFNEL_03512 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HMCIFNEL_03513 2.5e-71 hspX O Belongs to the small heat shock protein (HSP20) family
HMCIFNEL_03514 1.2e-48 yppG S YppG-like protein
HMCIFNEL_03516 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
HMCIFNEL_03519 2.6e-188 yppC S Protein of unknown function (DUF2515)
HMCIFNEL_03520 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMCIFNEL_03521 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HMCIFNEL_03522 4.7e-93 ypoC
HMCIFNEL_03523 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMCIFNEL_03524 5.7e-129 dnaD L DNA replication protein DnaD
HMCIFNEL_03525 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HMCIFNEL_03526 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HMCIFNEL_03527 3.4e-80 ypmB S protein conserved in bacteria
HMCIFNEL_03528 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HMCIFNEL_03529 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMCIFNEL_03530 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HMCIFNEL_03531 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HMCIFNEL_03532 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HMCIFNEL_03533 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMCIFNEL_03534 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMCIFNEL_03535 2e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HMCIFNEL_03536 7.6e-129 bshB1 S proteins, LmbE homologs
HMCIFNEL_03537 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HMCIFNEL_03538 7e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMCIFNEL_03539 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HMCIFNEL_03540 1.8e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HMCIFNEL_03541 6.1e-143 ypjB S sporulation protein
HMCIFNEL_03542 1.1e-99 ypjA S membrane
HMCIFNEL_03543 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HMCIFNEL_03544 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HMCIFNEL_03545 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HMCIFNEL_03546 1e-75 ypiF S Protein of unknown function (DUF2487)
HMCIFNEL_03547 2.8e-99 ypiB S Belongs to the UPF0302 family
HMCIFNEL_03548 4.1e-234 S COG0457 FOG TPR repeat
HMCIFNEL_03549 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMCIFNEL_03550 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HMCIFNEL_03551 4.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMCIFNEL_03552 9.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMCIFNEL_03553 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMCIFNEL_03554 1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HMCIFNEL_03555 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HMCIFNEL_03556 2.3e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMCIFNEL_03557 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMCIFNEL_03558 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HMCIFNEL_03559 6.5e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMCIFNEL_03560 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMCIFNEL_03561 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HMCIFNEL_03562 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HMCIFNEL_03563 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMCIFNEL_03564 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMCIFNEL_03565 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HMCIFNEL_03566 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HMCIFNEL_03567 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HMCIFNEL_03568 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMCIFNEL_03569 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HMCIFNEL_03570 6e-137 yphF
HMCIFNEL_03571 1.6e-18 yphE S Protein of unknown function (DUF2768)
HMCIFNEL_03572 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMCIFNEL_03573 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMCIFNEL_03574 6e-28 ypzH
HMCIFNEL_03575 7.2e-161 seaA S YIEGIA protein
HMCIFNEL_03576 1.9e-101 yphA
HMCIFNEL_03577 1e-07 S YpzI-like protein
HMCIFNEL_03578 4.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMCIFNEL_03579 3.1e-204 rpsA 1.17.7.4 J Ribosomal protein S1
HMCIFNEL_03580 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMCIFNEL_03581 1.8e-23 S Family of unknown function (DUF5359)
HMCIFNEL_03582 5.2e-108 ypfA M Flagellar protein YcgR
HMCIFNEL_03583 9.3e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HMCIFNEL_03584 5.7e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HMCIFNEL_03585 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
HMCIFNEL_03586 2.1e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HMCIFNEL_03587 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMCIFNEL_03588 9.1e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HMCIFNEL_03589 3.4e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HMCIFNEL_03590 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HMCIFNEL_03591 5.5e-74 ypbE M Lysin motif
HMCIFNEL_03592 6.9e-99 ypbD S metal-dependent membrane protease
HMCIFNEL_03593 6e-285 recQ 3.6.4.12 L DNA helicase
HMCIFNEL_03594 1.9e-200 ypbB 5.1.3.1 S protein conserved in bacteria
HMCIFNEL_03595 4.7e-41 fer C Ferredoxin
HMCIFNEL_03596 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMCIFNEL_03597 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMCIFNEL_03598 6.5e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMCIFNEL_03599 3.1e-198 rsiX
HMCIFNEL_03600 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_03601 0.0 resE 2.7.13.3 T Histidine kinase
HMCIFNEL_03602 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_03603 4.4e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HMCIFNEL_03604 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HMCIFNEL_03605 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HMCIFNEL_03606 2e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMCIFNEL_03607 1.9e-87 spmB S Spore maturation protein
HMCIFNEL_03608 5.9e-103 spmA S Spore maturation protein
HMCIFNEL_03609 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HMCIFNEL_03610 4e-98 ypuI S Protein of unknown function (DUF3907)
HMCIFNEL_03611 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMCIFNEL_03612 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMCIFNEL_03613 3.9e-90 ypuF S Domain of unknown function (DUF309)
HMCIFNEL_03614 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMCIFNEL_03615 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMCIFNEL_03616 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HMCIFNEL_03617 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HMCIFNEL_03618 9.3e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMCIFNEL_03619 7.8e-55 ypuD
HMCIFNEL_03620 8e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HMCIFNEL_03622 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HMCIFNEL_03623 1.4e-08 S SNARE associated Golgi protein
HMCIFNEL_03625 4.7e-09 eaeH M Domain of Unknown Function (DUF1259)
HMCIFNEL_03627 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMCIFNEL_03628 1.3e-149 ypuA S Secreted protein
HMCIFNEL_03629 8.8e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMCIFNEL_03630 1.7e-271 spoVAF EG Stage V sporulation protein AF
HMCIFNEL_03631 1.4e-110 spoVAEA S stage V sporulation protein
HMCIFNEL_03632 2.2e-57 spoVAEB S stage V sporulation protein
HMCIFNEL_03633 2.9e-190 spoVAD I Stage V sporulation protein AD
HMCIFNEL_03634 2.3e-78 spoVAC S stage V sporulation protein AC
HMCIFNEL_03635 9.1e-50 spoVAB S Stage V sporulation protein AB
HMCIFNEL_03636 9.6e-112 spoVAA S Stage V sporulation protein AA
HMCIFNEL_03637 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCIFNEL_03638 5.1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HMCIFNEL_03639 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HMCIFNEL_03640 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HMCIFNEL_03641 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HMCIFNEL_03642 6.7e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMCIFNEL_03643 2.6e-166 xerD L recombinase XerD
HMCIFNEL_03644 1.4e-36 S Protein of unknown function (DUF4227)
HMCIFNEL_03645 2.4e-80 fur P Belongs to the Fur family
HMCIFNEL_03646 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HMCIFNEL_03647 6.5e-31 yqkK
HMCIFNEL_03648 5.5e-242 mleA 1.1.1.38 C malic enzyme
HMCIFNEL_03649 9.1e-235 mleN C Na H antiporter
HMCIFNEL_03650 1.9e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HMCIFNEL_03651 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase
HMCIFNEL_03652 1.3e-57 ansR K Transcriptional regulator
HMCIFNEL_03653 3.1e-220 yqxK 3.6.4.12 L DNA helicase
HMCIFNEL_03654 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HMCIFNEL_03656 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HMCIFNEL_03657 9.1e-12 yqkE S Protein of unknown function (DUF3886)
HMCIFNEL_03658 1.2e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HMCIFNEL_03659 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HMCIFNEL_03660 2.8e-54 yqkB S Belongs to the HesB IscA family
HMCIFNEL_03661 2.2e-193 yqkA K GrpB protein
HMCIFNEL_03662 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HMCIFNEL_03663 8.1e-87 yqjY K acetyltransferase
HMCIFNEL_03664 1.7e-49 S YolD-like protein
HMCIFNEL_03665 2e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMCIFNEL_03667 5.8e-225 yqjV G Major Facilitator Superfamily
HMCIFNEL_03669 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCIFNEL_03670 3.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HMCIFNEL_03671 2.1e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HMCIFNEL_03672 1.7e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_03673 1.6e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HMCIFNEL_03674 6.4e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMCIFNEL_03675 2.3e-254 xynT G MFS/sugar transport protein
HMCIFNEL_03676 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HMCIFNEL_03677 2.3e-212 xylR GK ROK family
HMCIFNEL_03678 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HMCIFNEL_03679 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HMCIFNEL_03680 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMCIFNEL_03681 2.5e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMCIFNEL_03682 2.8e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMCIFNEL_03683 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMCIFNEL_03684 3.4e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMCIFNEL_03685 4.5e-24 yqzJ
HMCIFNEL_03686 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMCIFNEL_03687 4.7e-132 yqjF S Uncharacterized conserved protein (COG2071)
HMCIFNEL_03688 5.9e-97 S Protein of unknown function (DUF421)
HMCIFNEL_03689 2.1e-282 clsA_1 I PLD-like domain
HMCIFNEL_03690 1.2e-70 S Protein of unknown function (DUF421)
HMCIFNEL_03691 2.8e-07 S Protein of unknown function (DUF421)
HMCIFNEL_03692 1.2e-149 yetF1 S membrane
HMCIFNEL_03693 5.8e-29 S Protein of unknown function (DUF1657)
HMCIFNEL_03694 2.5e-56 spoVAE S stage V sporulation protein
HMCIFNEL_03695 1e-195 spoVAD I Stage V sporulation protein AD
HMCIFNEL_03696 2.6e-80 spoVAC S stage V sporulation protein AC
HMCIFNEL_03697 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMCIFNEL_03698 6e-26 S Protein of unknown function (DUF1657)
HMCIFNEL_03699 1.1e-23 cat P Catalase
HMCIFNEL_03700 2.1e-91 cat P Catalase
HMCIFNEL_03701 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HMCIFNEL_03703 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HMCIFNEL_03704 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HMCIFNEL_03705 4.2e-29 S Domain of unknown function (DUF4177)
HMCIFNEL_03706 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMCIFNEL_03707 3.6e-82 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HMCIFNEL_03708 3.5e-96 L Transposase
HMCIFNEL_03710 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HMCIFNEL_03711 0.0 rocB E arginine degradation protein
HMCIFNEL_03712 1.3e-72 L Integrase core domain
HMCIFNEL_03713 9.3e-48 S SMI1-KNR4 cell-wall
HMCIFNEL_03714 1.8e-206 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HMCIFNEL_03715 3.5e-42 S Putative amidase domain
HMCIFNEL_03716 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMCIFNEL_03717 1.1e-306 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HMCIFNEL_03718 7.3e-68
HMCIFNEL_03719 6.1e-153 M Pectate lyase superfamily protein
HMCIFNEL_03720 2.2e-12 K Helix-turn-helix XRE-family like proteins
HMCIFNEL_03721 1.9e-44 M D-alanyl-D-alanine carboxypeptidase
HMCIFNEL_03725 3.5e-96 L Transposase
HMCIFNEL_03727 1.8e-98 amyE 3.2.1.1 GH13 G alpha-amylase
HMCIFNEL_03728 2.6e-269 amyE 3.2.1.1 GH13 G alpha-amylase
HMCIFNEL_03729 2.8e-46 ycgB
HMCIFNEL_03730 1.6e-255 ycgA S Membrane
HMCIFNEL_03731 5.6e-214 amhX S amidohydrolase
HMCIFNEL_03732 3.4e-163 opuAC E glycine betaine
HMCIFNEL_03733 1.3e-127 opuAB P glycine betaine
HMCIFNEL_03734 5.7e-228 proV 3.6.3.32 E glycine betaine
HMCIFNEL_03735 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMCIFNEL_03736 3.2e-185 yceJ EGP Uncharacterised MFS-type transporter YbfB
HMCIFNEL_03737 3.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
HMCIFNEL_03738 2e-192 yceH P Belongs to the TelA family
HMCIFNEL_03739 0.0 yceG S Putative component of 'biosynthetic module'
HMCIFNEL_03740 6.3e-137 terC P Protein of unknown function (DUF475)
HMCIFNEL_03741 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HMCIFNEL_03742 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HMCIFNEL_03743 1.6e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HMCIFNEL_03744 2.8e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMCIFNEL_03745 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HMCIFNEL_03746 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HMCIFNEL_03747 1.6e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
HMCIFNEL_03748 9.8e-293 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HMCIFNEL_03749 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
HMCIFNEL_03750 6.7e-172 S response regulator aspartate phosphatase
HMCIFNEL_03751 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
HMCIFNEL_03752 2.6e-256 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_03753 9.4e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_03754 1.1e-179 ycdA S Domain of unknown function (DUF5105)
HMCIFNEL_03755 8.5e-90 yccK C Aldo keto reductase
HMCIFNEL_03756 6.5e-61 yccK C Aldo keto reductase
HMCIFNEL_03757 4.2e-201 natB CP ABC-2 family transporter protein
HMCIFNEL_03758 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HMCIFNEL_03759 2.5e-124 lytR_2 T LytTr DNA-binding domain
HMCIFNEL_03760 3.3e-159 2.7.13.3 T GHKL domain
HMCIFNEL_03761 2.3e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
HMCIFNEL_03762 4.6e-56 S RDD family
HMCIFNEL_03763 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HMCIFNEL_03764 2.5e-150 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HMCIFNEL_03765 3.1e-101 yxaF K Transcriptional regulator
HMCIFNEL_03766 1.8e-230 lmrB EGP the major facilitator superfamily
HMCIFNEL_03767 1.6e-202 ycbU E Selenocysteine lyase
HMCIFNEL_03768 9.1e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMCIFNEL_03769 1.3e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMCIFNEL_03770 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HMCIFNEL_03771 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HMCIFNEL_03772 1.1e-43 ycbR T vWA found in TerF C terminus
HMCIFNEL_03773 2.8e-64 ycbR T vWA found in TerF C terminus
HMCIFNEL_03774 2.5e-195 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCIFNEL_03775 1.8e-70 argO S Lysine exporter protein LysE YggA
HMCIFNEL_03776 8.7e-122 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HMCIFNEL_03777 2.8e-30 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMCIFNEL_03778 1e-14 E argininosuccinate synthase activity
HMCIFNEL_03779 1.3e-82 S Protein of unknown function (DUF444)
HMCIFNEL_03780 2e-82 I Fatty acid desaturase
HMCIFNEL_03781 2.3e-123 yjeH E Amino acid permease
HMCIFNEL_03782 9.5e-99 asd 1.2.1.11, 1.2.1.12 E Belongs to the aspartate-semialdehyde dehydrogenase family
HMCIFNEL_03783 1.2e-34 S CGNR zinc finger
HMCIFNEL_03784 4.5e-40 MA20_18655 S flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase
HMCIFNEL_03785 1.5e-26 4.4.1.5 E lactoylglutathione lyase activity
HMCIFNEL_03786 9.7e-17 S NIPSNAP family containing protein
HMCIFNEL_03787 8.5e-51 S B3/4 domain
HMCIFNEL_03789 3.4e-76 sleB 3.5.1.28 M Cell wall
HMCIFNEL_03790 1.3e-50 ycbP S Protein of unknown function (DUF2512)
HMCIFNEL_03791 5.6e-113 S ABC-2 family transporter protein
HMCIFNEL_03792 3.1e-167 ycbN V ABC transporter, ATP-binding protein
HMCIFNEL_03793 1.5e-77 T PhoQ Sensor
HMCIFNEL_03794 2.7e-77 T PhoQ Sensor
HMCIFNEL_03795 6.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCIFNEL_03796 4.9e-168 eamA1 EG spore germination
HMCIFNEL_03797 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HMCIFNEL_03798 2.4e-53 ycbJ S Macrolide 2'-phosphotransferase
HMCIFNEL_03799 5.1e-96 ycbJ S Macrolide 2'-phosphotransferase
HMCIFNEL_03800 2.9e-78 garD 4.2.1.42, 4.2.1.7 G Altronate
HMCIFNEL_03801 1e-68 garD 4.2.1.42, 4.2.1.7 G Altronate
HMCIFNEL_03802 2.1e-123 ycbG K FCD
HMCIFNEL_03803 1.4e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HMCIFNEL_03804 4.7e-157 gudP G COG0477 Permeases of the major facilitator superfamily
HMCIFNEL_03805 6.1e-48 gudP G COG0477 Permeases of the major facilitator superfamily
HMCIFNEL_03806 9e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMCIFNEL_03807 1.9e-172 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HMCIFNEL_03808 6.5e-168 glnL T Regulator
HMCIFNEL_03809 4.7e-228 phoQ 2.7.13.3 T Histidine kinase
HMCIFNEL_03810 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HMCIFNEL_03811 8.1e-255 agcS E Sodium alanine symporter
HMCIFNEL_03813 1.1e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HMCIFNEL_03814 3.3e-261 mmuP E amino acid
HMCIFNEL_03815 1.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMCIFNEL_03817 3.1e-128 K UTRA
HMCIFNEL_03818 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMCIFNEL_03819 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMCIFNEL_03820 1.4e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMCIFNEL_03821 1.5e-191 yceA S Belongs to the UPF0176 family
HMCIFNEL_03822 9e-248 S Erythromycin esterase
HMCIFNEL_03823 2e-45 ybfN
HMCIFNEL_03824 1.6e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HMCIFNEL_03825 2.7e-85 ybfM S SNARE associated Golgi protein
HMCIFNEL_03826 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMCIFNEL_03827 1.6e-163 S Alpha/beta hydrolase family
HMCIFNEL_03829 1.1e-175 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HMCIFNEL_03830 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMCIFNEL_03831 3.3e-144 msmR K AraC-like ligand binding domain
HMCIFNEL_03832 1.3e-48 ybfH EG EamA-like transporter family
HMCIFNEL_03833 5.8e-67 ybfH EG EamA-like transporter family
HMCIFNEL_03834 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HMCIFNEL_03836 1e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
HMCIFNEL_03837 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
HMCIFNEL_03838 1.6e-33 S Protein of unknown function (DUF2651)
HMCIFNEL_03839 7.3e-258 glpT G -transporter
HMCIFNEL_03840 2.4e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMCIFNEL_03841 1.5e-289 ybeC E amino acid
HMCIFNEL_03842 4.9e-41 ybyB
HMCIFNEL_03843 1.1e-32 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HMCIFNEL_03844 2.2e-169 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HMCIFNEL_03845 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
HMCIFNEL_03846 4.9e-30 ybxH S Family of unknown function (DUF5370)
HMCIFNEL_03847 1.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HMCIFNEL_03848 1.3e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HMCIFNEL_03849 9.2e-212 ybdO S Domain of unknown function (DUF4885)
HMCIFNEL_03850 7.7e-152 ybdN
HMCIFNEL_03851 3.9e-139 KLT Protein tyrosine kinase
HMCIFNEL_03853 1.8e-168 T His Kinase A (phospho-acceptor) domain
HMCIFNEL_03854 1.3e-122 T Transcriptional regulatory protein, C terminal
HMCIFNEL_03855 5.5e-178 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMCIFNEL_03856 9.6e-79 txn CO Thioredoxin-like
HMCIFNEL_03857 7.8e-91 C HEAT repeats
HMCIFNEL_03858 8e-247 skfF S ABC transporter
HMCIFNEL_03859 7.5e-132 skfE V ABC transporter
HMCIFNEL_03860 2.5e-275 V CAAX protease self-immunity
HMCIFNEL_03861 9.1e-239 J 4Fe-4S single cluster domain
HMCIFNEL_03863 4.5e-203 ybcL EGP Major facilitator Superfamily
HMCIFNEL_03864 5.1e-50 ybzH K Helix-turn-helix domain
HMCIFNEL_03865 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HMCIFNEL_03866 8.7e-47
HMCIFNEL_03868 1.3e-93 can 4.2.1.1 P carbonic anhydrase
HMCIFNEL_03869 0.0 ybcC S Belongs to the UPF0753 family
HMCIFNEL_03870 7e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HMCIFNEL_03871 1.4e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMCIFNEL_03872 3.2e-118 adaA 3.2.2.21 K Transcriptional regulator
HMCIFNEL_03873 9.6e-169 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HMCIFNEL_03874 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMCIFNEL_03875 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMCIFNEL_03876 5.7e-224 ybbR S protein conserved in bacteria
HMCIFNEL_03877 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMCIFNEL_03878 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HMCIFNEL_03879 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_03885 5.7e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HMCIFNEL_03886 1.9e-86 ybbJ J acetyltransferase
HMCIFNEL_03887 3.9e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMCIFNEL_03888 1.2e-149 ybbH K transcriptional
HMCIFNEL_03889 8.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMCIFNEL_03890 1.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HMCIFNEL_03891 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HMCIFNEL_03892 1.6e-235 ybbC 3.2.1.52 S protein conserved in bacteria
HMCIFNEL_03893 1.4e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HMCIFNEL_03894 2.4e-162 feuA P Iron-uptake system-binding protein
HMCIFNEL_03895 4e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_03896 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCIFNEL_03897 8.6e-139 ybbA S Putative esterase
HMCIFNEL_03898 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
HMCIFNEL_03899 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HMCIFNEL_03905 7.8e-08
HMCIFNEL_03913 2e-08
HMCIFNEL_03917 2.8e-54 ynaE S Domain of unknown function (DUF3885)
HMCIFNEL_03919 4.2e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HMCIFNEL_03920 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HMCIFNEL_03921 1.1e-44 S LrgA family
HMCIFNEL_03922 6.1e-115 yxaC M effector of murein hydrolase
HMCIFNEL_03923 5.3e-67 S TIGRFAM germination protein, Ger(x)C family
HMCIFNEL_03924 3.6e-99 EG Spore germination protein
HMCIFNEL_03925 3e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HMCIFNEL_03926 3.4e-39 S COG NOG14552 non supervised orthologous group
HMCIFNEL_03927 7.9e-88 L Tn3 transposase DDE domain
HMCIFNEL_03928 1.5e-75
HMCIFNEL_03929 1.2e-238 L COG3328 Transposase and inactivated derivatives
HMCIFNEL_03930 9.1e-50 L Transposase
HMCIFNEL_03931 8.6e-119 L COG2801 Transposase and inactivated derivatives
HMCIFNEL_03932 1.3e-72 L Integrase core domain
HMCIFNEL_03933 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
HMCIFNEL_03934 7.5e-253 iolT EGP Major facilitator Superfamily
HMCIFNEL_03935 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMCIFNEL_03936 5.3e-83 yncE S Protein of unknown function (DUF2691)
HMCIFNEL_03937 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HMCIFNEL_03938 5.2e-15
HMCIFNEL_03941 1.9e-163 S Thymidylate synthase
HMCIFNEL_03942 5.4e-32
HMCIFNEL_03944 1.2e-126 S Domain of unknown function, YrpD
HMCIFNEL_03947 7.9e-25 tatA U protein secretion
HMCIFNEL_03948 1.3e-51
HMCIFNEL_03949 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HMCIFNEL_03952 9e-284 gerAA EG Spore germination protein
HMCIFNEL_03953 7.9e-178 gerAB U Spore germination
HMCIFNEL_03954 1.9e-182 gerLC S Spore germination protein
HMCIFNEL_03955 2.9e-153 yndG S DoxX-like family
HMCIFNEL_03956 5.5e-113 yndH S Domain of unknown function (DUF4166)
HMCIFNEL_03957 2.3e-306 yndJ S YndJ-like protein
HMCIFNEL_03959 1.5e-135 yndL S Replication protein
HMCIFNEL_03960 5.6e-92 yndM S Protein of unknown function (DUF2512)
HMCIFNEL_03961 1.1e-77 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HMCIFNEL_03962 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMCIFNEL_03963 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HMCIFNEL_03964 2.9e-111 yneB L resolvase
HMCIFNEL_03965 1.3e-32 ynzC S UPF0291 protein
HMCIFNEL_03966 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMCIFNEL_03967 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HMCIFNEL_03968 1.8e-28 yneF S UPF0154 protein
HMCIFNEL_03969 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HMCIFNEL_03970 7.1e-127 ccdA O cytochrome c biogenesis protein
HMCIFNEL_03971 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HMCIFNEL_03972 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HMCIFNEL_03973 1.2e-73 yneK S Protein of unknown function (DUF2621)
HMCIFNEL_03974 5.9e-64 hspX O Spore coat protein
HMCIFNEL_03975 3.9e-19 sspP S Belongs to the SspP family
HMCIFNEL_03976 2.2e-14 sspO S Belongs to the SspO family
HMCIFNEL_03977 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HMCIFNEL_03978 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HMCIFNEL_03980 3.1e-08 sspN S Small acid-soluble spore protein N family
HMCIFNEL_03981 3.9e-35 tlp S Belongs to the Tlp family
HMCIFNEL_03982 1.2e-73 yneP S Thioesterase-like superfamily
HMCIFNEL_03983 1.9e-52 yneQ
HMCIFNEL_03984 4.1e-49 yneR S Belongs to the HesB IscA family
HMCIFNEL_03985 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMCIFNEL_03986 6.6e-69 yccU S CoA-binding protein
HMCIFNEL_03987 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMCIFNEL_03988 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMCIFNEL_03989 2.3e-12
HMCIFNEL_03990 8.6e-57 ynfC
HMCIFNEL_03991 9e-251 agcS E Sodium alanine symporter
HMCIFNEL_03992 4.2e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HMCIFNEL_03994 2e-91 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HMCIFNEL_03995 1.8e-136 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HMCIFNEL_03996 1.4e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HMCIFNEL_03997 1.4e-75 yngA S membrane
HMCIFNEL_03998 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMCIFNEL_03999 5.5e-104 yngC S membrane-associated protein
HMCIFNEL_04000 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
HMCIFNEL_04001 4.5e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HMCIFNEL_04002 1.7e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HMCIFNEL_04003 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HMCIFNEL_04004 7.3e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HMCIFNEL_04005 5.6e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HMCIFNEL_04006 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HMCIFNEL_04007 7e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HMCIFNEL_04008 8.5e-303 yngK T Glycosyl hydrolase-like 10
HMCIFNEL_04009 2.8e-64 yngL S Protein of unknown function (DUF1360)
HMCIFNEL_04010 2.6e-36 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HMCIFNEL_04011 2e-161 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HMCIFNEL_04012 1e-154 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HMCIFNEL_04013 1e-260 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HMCIFNEL_04014 1.7e-290 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCIFNEL_04015 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMCIFNEL_04016 1.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HMCIFNEL_04017 6.9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
HMCIFNEL_04018 2.3e-246 yoeA V MATE efflux family protein
HMCIFNEL_04019 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HMCIFNEL_04021 2.2e-96 L Integrase
HMCIFNEL_04022 3e-34 yoeD G Helix-turn-helix domain
HMCIFNEL_04023 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HMCIFNEL_04024 8.8e-156 gltR1 K Transcriptional regulator
HMCIFNEL_04025 1.8e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HMCIFNEL_04026 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HMCIFNEL_04027 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HMCIFNEL_04028 7.8e-155 gltC K Transcriptional regulator
HMCIFNEL_04029 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMCIFNEL_04030 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMCIFNEL_04031 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HMCIFNEL_04032 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCIFNEL_04033 6e-38 yoxC S Bacterial protein of unknown function (DUF948)
HMCIFNEL_04034 1.5e-69 yoxB
HMCIFNEL_04035 6e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMCIFNEL_04036 4.5e-127 V ABC-2 family transporter protein
HMCIFNEL_04037 3.7e-94 V ABC-2 family transporter protein
HMCIFNEL_04038 9.7e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
HMCIFNEL_04039 2.5e-79 hpr K helix_turn_helix multiple antibiotic resistance protein
HMCIFNEL_04040 1.2e-233 yoaB EGP Major facilitator Superfamily
HMCIFNEL_04041 5.7e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HMCIFNEL_04042 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMCIFNEL_04043 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMCIFNEL_04044 6.5e-34 yoaF
HMCIFNEL_04045 5e-08 ywlA S Uncharacterised protein family (UPF0715)
HMCIFNEL_04046 2.6e-13
HMCIFNEL_04047 1.3e-37 S Protein of unknown function (DUF4025)
HMCIFNEL_04048 1.6e-130 mcpU NT methyl-accepting chemotaxis protein
HMCIFNEL_04049 6.2e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HMCIFNEL_04050 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HMCIFNEL_04051 5.2e-111 yoaK S Membrane
HMCIFNEL_04052 5.2e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HMCIFNEL_04053 6.6e-130 yoqW S Belongs to the SOS response-associated peptidase family
HMCIFNEL_04055 5e-164 oxdC 4.1.1.2 G Oxalate decarboxylase
HMCIFNEL_04056 1.2e-52 oxdC 4.1.1.2 G Oxalate decarboxylase
HMCIFNEL_04059 4.9e-36
HMCIFNEL_04060 1.1e-169 yoaR V vancomycin resistance protein
HMCIFNEL_04061 7.3e-75 yoaS S Protein of unknown function (DUF2975)
HMCIFNEL_04062 4.4e-30 yozG K Transcriptional regulator
HMCIFNEL_04063 2.4e-147 yoaT S Protein of unknown function (DUF817)
HMCIFNEL_04064 8.2e-158 yoaU K LysR substrate binding domain
HMCIFNEL_04065 5.3e-156 yijE EG EamA-like transporter family
HMCIFNEL_04066 1.6e-76 yoaW
HMCIFNEL_04071 2e-08
HMCIFNEL_04076 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMCIFNEL_04077 1.5e-134 L Integrase core domain
HMCIFNEL_04078 6e-44 tnpIS3 L Transposase
HMCIFNEL_04081 2e-08
HMCIFNEL_04085 1.1e-94 L COG3666 Transposase and inactivated derivatives
HMCIFNEL_04086 1.2e-13 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMCIFNEL_04087 1.5e-38 EG Spore germination protein
HMCIFNEL_04088 3e-36 L transposase activity
HMCIFNEL_04089 4.2e-57 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HMCIFNEL_04090 1.6e-21 yhaL S Sporulation protein YhaL
HMCIFNEL_04091 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HMCIFNEL_04092 0.0 yhaN L AAA domain
HMCIFNEL_04093 2.2e-221 yhaO L DNA repair exonuclease
HMCIFNEL_04094 1e-213 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HMCIFNEL_04095 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HMCIFNEL_04096 2.4e-26 S YhzD-like protein
HMCIFNEL_04097 2.3e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
HMCIFNEL_04099 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HMCIFNEL_04100 1.8e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
HMCIFNEL_04101 1e-292 hemZ H coproporphyrinogen III oxidase
HMCIFNEL_04102 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HMCIFNEL_04103 3.1e-53 yhaZ L DNA alkylation repair enzyme
HMCIFNEL_04104 1.2e-131 yhaZ L DNA alkylation repair enzyme
HMCIFNEL_04105 9.5e-48 yheA S Belongs to the UPF0342 family
HMCIFNEL_04106 6.3e-202 yheB S Belongs to the UPF0754 family
HMCIFNEL_04107 4.3e-216 yheC HJ YheC/D like ATP-grasp
HMCIFNEL_04108 1.1e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HMCIFNEL_04109 1.3e-36 yheE S Family of unknown function (DUF5342)
HMCIFNEL_04110 6.3e-28 sspB S spore protein
HMCIFNEL_04111 2.9e-108 yheG GM NAD(P)H-binding
HMCIFNEL_04112 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMCIFNEL_04113 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMCIFNEL_04114 3.1e-84 nhaX T Belongs to the universal stress protein A family
HMCIFNEL_04115 1.2e-231 nhaC C Na H antiporter
HMCIFNEL_04116 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HMCIFNEL_04117 3.9e-148 yheN G deacetylase
HMCIFNEL_04118 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HMCIFNEL_04119 5.6e-203 yhdY M Mechanosensitive ion channel
HMCIFNEL_04121 6.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMCIFNEL_04122 6.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMCIFNEL_04123 1.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMCIFNEL_04124 1.8e-238 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HMCIFNEL_04125 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
HMCIFNEL_04126 8e-74 cueR K transcriptional
HMCIFNEL_04127 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HMCIFNEL_04128 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HMCIFNEL_04129 5.7e-191 yhdN C Aldo keto reductase
HMCIFNEL_04130 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HMCIFNEL_04131 6.6e-201 yhdL S Sigma factor regulator N-terminal
HMCIFNEL_04132 8.1e-45 yhdK S Sigma-M inhibitor protein
HMCIFNEL_04133 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMCIFNEL_04134 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCIFNEL_04135 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMCIFNEL_04136 3.4e-250 yhdG E amino acid
HMCIFNEL_04137 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMCIFNEL_04138 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
HMCIFNEL_04139 3.8e-162 citR K Transcriptional regulator
HMCIFNEL_04140 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HMCIFNEL_04141 3.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HMCIFNEL_04142 2e-261 ycgB S Stage V sporulation protein R
HMCIFNEL_04143 9.6e-238 ygxB M Conserved TM helix
HMCIFNEL_04144 1e-75 nsrR K Transcriptional regulator
HMCIFNEL_04145 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HMCIFNEL_04146 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HMCIFNEL_04147 1.2e-38 yhdB S YhdB-like protein
HMCIFNEL_04148 1.2e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
HMCIFNEL_04149 2e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMCIFNEL_04150 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
HMCIFNEL_04151 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HMCIFNEL_04152 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HMCIFNEL_04153 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMCIFNEL_04154 1.4e-150 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HMCIFNEL_04155 3.4e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HMCIFNEL_04156 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMCIFNEL_04157 2.3e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMCIFNEL_04158 1e-119 yhcW 5.4.2.6 S hydrolase
HMCIFNEL_04159 3.8e-67 yhcV S COG0517 FOG CBS domain
HMCIFNEL_04160 9.3e-68 yhcU S Family of unknown function (DUF5365)
HMCIFNEL_04161 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMCIFNEL_04162 1.1e-101 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HMCIFNEL_04163 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HMCIFNEL_04164 1.6e-96 yhcQ M Spore coat protein
HMCIFNEL_04165 1e-158 yhcP
HMCIFNEL_04166 2.1e-61 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMCIFNEL_04167 4.9e-41 yhcM
HMCIFNEL_04168 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMCIFNEL_04169 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HMCIFNEL_04170 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
HMCIFNEL_04171 1e-30 cspB K Cold-shock protein
HMCIFNEL_04172 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMCIFNEL_04173 7.2e-164 yhcH V ABC transporter, ATP-binding protein
HMCIFNEL_04174 8.8e-122 yhcG V ABC transporter, ATP-binding protein
HMCIFNEL_04175 1.6e-58 yhcF K Transcriptional regulator
HMCIFNEL_04176 3.6e-52
HMCIFNEL_04177 2.8e-37 yhcC
HMCIFNEL_04178 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HMCIFNEL_04179 6.9e-271 yhcA EGP Major facilitator Superfamily
HMCIFNEL_04180 3.8e-87 yhbJ V COG1566 Multidrug resistance efflux pump
HMCIFNEL_04181 2.2e-76 yhbI K DNA-binding transcription factor activity
HMCIFNEL_04182 2.5e-225 yhbH S Belongs to the UPF0229 family
HMCIFNEL_04183 0.0 prkA T Ser protein kinase
HMCIFNEL_04184 2.7e-57 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HMCIFNEL_04185 1.4e-102 yhbD K Protein of unknown function (DUF4004)
HMCIFNEL_04186 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMCIFNEL_04187 3.5e-174 yhbB S Putative amidase domain
HMCIFNEL_04188 5.1e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMCIFNEL_04189 7.9e-114 yhzB S B3/4 domain
HMCIFNEL_04191 4.4e-29 K Transcriptional regulator
HMCIFNEL_04192 1.3e-76 ygaO
HMCIFNEL_04193 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMCIFNEL_04195 2.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HMCIFNEL_04196 1.3e-96 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HMCIFNEL_04197 1.1e-37 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HMCIFNEL_04198 7.3e-170 ssuA M Sulfonate ABC transporter
HMCIFNEL_04199 8.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HMCIFNEL_04200 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HMCIFNEL_04202 7.6e-263 ygaK C Berberine and berberine like
HMCIFNEL_04203 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HMCIFNEL_04204 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HMCIFNEL_04205 1.2e-26
HMCIFNEL_04206 5e-142 spo0M S COG4326 Sporulation control protein
HMCIFNEL_04207 1.3e-72 L Integrase core domain
HMCIFNEL_04208 7.2e-49 cyoB 1.10.3.10, 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMCIFNEL_04209 5.4e-69 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMCIFNEL_04210 3.2e-30 sirB2 S Invasion gene expression up-regulator SirB
HMCIFNEL_04211 1.1e-43 rimP S Required for maturation of 30S ribosomal subunits
HMCIFNEL_04212 1.9e-33
HMCIFNEL_04213 9.6e-26 S Phage regulatory protein
HMCIFNEL_04214 4.1e-17
HMCIFNEL_04215 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HMCIFNEL_04216 3.9e-11 yqfQ S YqfQ-like protein
HMCIFNEL_04217 8.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMCIFNEL_04218 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMCIFNEL_04219 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HMCIFNEL_04220 8.2e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HMCIFNEL_04221 1.9e-77 zur P Belongs to the Fur family
HMCIFNEL_04222 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HMCIFNEL_04223 3.7e-61 yqfX S membrane
HMCIFNEL_04224 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HMCIFNEL_04225 4.4e-46 yqfZ M LysM domain
HMCIFNEL_04226 3.9e-131 yqgB S Protein of unknown function (DUF1189)
HMCIFNEL_04227 4e-73 yqgC S protein conserved in bacteria
HMCIFNEL_04228 3.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HMCIFNEL_04229 1.8e-229 yqgE EGP Major facilitator superfamily
HMCIFNEL_04230 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HMCIFNEL_04231 2.4e-150 pstS P Phosphate
HMCIFNEL_04232 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HMCIFNEL_04233 1.3e-157 pstA P Phosphate transport system permease
HMCIFNEL_04234 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMCIFNEL_04235 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMCIFNEL_04236 7.3e-72 yqzC S YceG-like family
HMCIFNEL_04237 3.5e-50 yqzD
HMCIFNEL_04239 8.1e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HMCIFNEL_04240 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMCIFNEL_04241 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMCIFNEL_04242 2.5e-09 yqgO
HMCIFNEL_04243 3.1e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HMCIFNEL_04244 4.7e-32 yqgQ S Protein conserved in bacteria
HMCIFNEL_04245 3.4e-180 glcK 2.7.1.2 G Glucokinase
HMCIFNEL_04246 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMCIFNEL_04247 1.6e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HMCIFNEL_04248 8.8e-198 yqgU
HMCIFNEL_04249 6.9e-50 yqgV S Thiamine-binding protein
HMCIFNEL_04250 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HMCIFNEL_04251 2.3e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HMCIFNEL_04252 2e-36 yqgY S Protein of unknown function (DUF2626)
HMCIFNEL_04253 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HMCIFNEL_04255 1.5e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMCIFNEL_04256 2.2e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HMCIFNEL_04257 6.7e-173 corA P Mg2 transporter protein
HMCIFNEL_04258 5e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HMCIFNEL_04259 2.4e-57 comGB NU COG1459 Type II secretory pathway, component PulF
HMCIFNEL_04260 1.2e-95 comGB NU COG1459 Type II secretory pathway, component PulF
HMCIFNEL_04261 1.2e-46 comGC U Required for transformation and DNA binding
HMCIFNEL_04262 4.1e-69 gspH NU protein transport across the cell outer membrane
HMCIFNEL_04263 1.3e-57 comGE
HMCIFNEL_04264 6e-45 comGF U Putative Competence protein ComGF
HMCIFNEL_04265 1.2e-43 S ComG operon protein 7
HMCIFNEL_04266 5.2e-26 yqzE S YqzE-like protein
HMCIFNEL_04267 2.8e-53 yqzG S Protein of unknown function (DUF3889)
HMCIFNEL_04268 4.8e-97 yqxM
HMCIFNEL_04269 5.7e-58 sipW 3.4.21.89 U Signal peptidase
HMCIFNEL_04270 4.3e-141 tasA S Cell division protein FtsN
HMCIFNEL_04271 1e-54 sinR K transcriptional
HMCIFNEL_04272 1.2e-24 sinI S Anti-repressor SinI
HMCIFNEL_04273 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HMCIFNEL_04274 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HMCIFNEL_04275 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HMCIFNEL_04276 1.9e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HMCIFNEL_04277 4.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HMCIFNEL_04278 3.3e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
HMCIFNEL_04279 5.7e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HMCIFNEL_04280 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HMCIFNEL_04281 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
HMCIFNEL_04282 2.2e-61 yqhP
HMCIFNEL_04283 1.5e-172 yqhQ S Protein of unknown function (DUF1385)
HMCIFNEL_04284 6.6e-93 yqhR S Conserved membrane protein YqhR
HMCIFNEL_04285 1.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HMCIFNEL_04286 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HMCIFNEL_04287 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMCIFNEL_04288 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HMCIFNEL_04289 4e-170 spoIIIAA S stage III sporulation protein AA
HMCIFNEL_04290 1.1e-84 spoIIIAB S Stage III sporulation protein
HMCIFNEL_04291 7.6e-29 spoIIIAC S stage III sporulation protein AC
HMCIFNEL_04292 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HMCIFNEL_04293 1.3e-197 spoIIIAE S stage III sporulation protein AE
HMCIFNEL_04294 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HMCIFNEL_04295 2.2e-109 spoIIIAG S stage III sporulation protein AG
HMCIFNEL_04296 2.9e-90 spoIIIAH S SpoIIIAH-like protein
HMCIFNEL_04297 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMCIFNEL_04298 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HMCIFNEL_04299 8.1e-67 yqhY S protein conserved in bacteria
HMCIFNEL_04300 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMCIFNEL_04301 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMCIFNEL_04302 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMCIFNEL_04303 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMCIFNEL_04304 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMCIFNEL_04305 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMCIFNEL_04306 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HMCIFNEL_04307 6.6e-78 argR K Regulates arginine biosynthesis genes
HMCIFNEL_04308 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
HMCIFNEL_04309 2.3e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
HMCIFNEL_04310 3.6e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HMCIFNEL_04312 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HMCIFNEL_04314 6e-27
HMCIFNEL_04315 7.8e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HMCIFNEL_04316 2.3e-128 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMCIFNEL_04317 2.9e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
HMCIFNEL_04318 2.6e-155 hbdA 1.1.1.157 I Dehydrogenase
HMCIFNEL_04319 6.7e-212 mmgC I acyl-CoA dehydrogenase
HMCIFNEL_04320 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HMCIFNEL_04321 8.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HMCIFNEL_04322 8.7e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HMCIFNEL_04323 4e-34 yqzF S Protein of unknown function (DUF2627)
HMCIFNEL_04324 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HMCIFNEL_04325 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HMCIFNEL_04326 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMCIFNEL_04327 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HMCIFNEL_04328 8.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMCIFNEL_04329 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMCIFNEL_04330 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMCIFNEL_04331 1.8e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMCIFNEL_04332 4.4e-152 bmrR K helix_turn_helix, mercury resistance
HMCIFNEL_04333 3.9e-207 norA EGP Major facilitator Superfamily
HMCIFNEL_04334 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMCIFNEL_04335 6e-76 yqiW S Belongs to the UPF0403 family
HMCIFNEL_04336 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HMCIFNEL_04337 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HMCIFNEL_04338 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HMCIFNEL_04339 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
HMCIFNEL_04340 8.8e-98 yqjB S protein conserved in bacteria
HMCIFNEL_04342 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HMCIFNEL_04343 5.5e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HMCIFNEL_04344 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HMCIFNEL_04345 1.3e-72 L Integrase core domain
HMCIFNEL_04346 3.2e-31 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCIFNEL_04347 6.3e-13 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMCIFNEL_04348 1.9e-20 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMCIFNEL_04349 2.1e-25 tcyB P COG0765 ABC-type amino acid transport system, permease component

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)