ORF_ID e_value Gene_name EC_number CAZy COGs Description
COOAKMDI_00001 1.5e-248 EGP Major facilitator Superfamily
COOAKMDI_00002 1.3e-246 rarA L Recombination factor protein RarA
COOAKMDI_00003 0.0 L DEAD DEAH box helicase
COOAKMDI_00004 1e-177 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
COOAKMDI_00005 2.4e-32 3.1.3.5 F 5'-nucleotidase, C-terminal domain
COOAKMDI_00006 2.6e-283 phoN I PAP2 superfamily
COOAKMDI_00007 2.8e-186 gluD E Binding-protein-dependent transport system inner membrane component
COOAKMDI_00008 3.9e-106 gluC E Binding-protein-dependent transport system inner membrane component
COOAKMDI_00009 1.5e-152 gluB ET Belongs to the bacterial solute-binding protein 3 family
COOAKMDI_00010 1e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
COOAKMDI_00011 7.9e-182 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
COOAKMDI_00012 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
COOAKMDI_00013 2.1e-260 hisS 6.1.1.21 J Histidyl-tRNA synthetase
COOAKMDI_00014 1.6e-185 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
COOAKMDI_00015 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
COOAKMDI_00016 3.3e-310 S Calcineurin-like phosphoesterase
COOAKMDI_00017 1.3e-113
COOAKMDI_00018 3.9e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COOAKMDI_00019 8e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
COOAKMDI_00020 2.5e-130 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
COOAKMDI_00021 1.8e-26 S Psort location Cytoplasmic, score
COOAKMDI_00022 2.2e-202 3.4.22.70 M Sortase family
COOAKMDI_00023 2.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COOAKMDI_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
COOAKMDI_00025 4.1e-99 K Bacterial regulatory proteins, tetR family
COOAKMDI_00026 1e-212 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
COOAKMDI_00027 2.3e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
COOAKMDI_00028 4.6e-40 S Protein of unknown function (DUF4244)
COOAKMDI_00029 8.2e-108 gspF NU Type II secretion system (T2SS), protein F
COOAKMDI_00030 1.7e-106 U Type ii secretion system
COOAKMDI_00031 4.7e-191 cpaF U Type II IV secretion system protein
COOAKMDI_00032 7.3e-127 cpaE D bacterial-type flagellum organization
COOAKMDI_00033 6.1e-134 dedA S SNARE associated Golgi protein
COOAKMDI_00034 2.6e-123 S HAD hydrolase, family IA, variant 3
COOAKMDI_00035 5.6e-141 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
COOAKMDI_00036 3.2e-230 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
COOAKMDI_00037 6.2e-210 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
COOAKMDI_00038 1.7e-214 F Psort location CytoplasmicMembrane, score 10.00
COOAKMDI_00039 2e-98 hspR K transcriptional regulator, MerR family
COOAKMDI_00040 5.7e-170 dnaJ1 O DnaJ molecular chaperone homology domain
COOAKMDI_00041 7e-55 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COOAKMDI_00042 0.0 dnaK O Heat shock 70 kDa protein
COOAKMDI_00043 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
COOAKMDI_00044 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
COOAKMDI_00045 4e-187 K Psort location Cytoplasmic, score
COOAKMDI_00046 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
COOAKMDI_00047 4.5e-191 K Transcriptional regulator
COOAKMDI_00048 5.6e-149 S Psort location Cytoplasmic, score
COOAKMDI_00049 1.1e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
COOAKMDI_00050 3e-59 bioY S BioY family
COOAKMDI_00051 3e-72 cbiO P ATPases associated with a variety of cellular activities
COOAKMDI_00052 1.8e-51 bioN P Cobalt transport protein
COOAKMDI_00053 2.5e-200 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
COOAKMDI_00055 5.2e-28 S Putative amidase domain
COOAKMDI_00057 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COOAKMDI_00058 2.2e-282 E Bacterial extracellular solute-binding proteins, family 5 Middle
COOAKMDI_00059 1.1e-127 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COOAKMDI_00060 8.3e-132 KT Transcriptional regulatory protein, C terminal
COOAKMDI_00061 4.5e-81
COOAKMDI_00062 1.6e-97 mntP P Probably functions as a manganese efflux pump
COOAKMDI_00063 2.8e-90 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
COOAKMDI_00064 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
COOAKMDI_00065 0.0 K RNA polymerase II activating transcription factor binding
COOAKMDI_00068 1.2e-08 K BetR domain
COOAKMDI_00075 2.4e-33 ycf41 L Single-strand binding protein family
COOAKMDI_00079 2.4e-22 V HNH endonuclease
COOAKMDI_00080 2.1e-25 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
COOAKMDI_00081 2.1e-13 S Protein of unknwon function (DUF3310)
COOAKMDI_00082 7.7e-09
COOAKMDI_00087 3e-12
COOAKMDI_00088 9.2e-09
COOAKMDI_00089 8.6e-49
COOAKMDI_00093 1.7e-25 L HNH endonuclease
COOAKMDI_00095 1.4e-219 S Terminase
COOAKMDI_00096 6.3e-181 S Phage portal protein, SPP1 Gp6-like
COOAKMDI_00097 6.1e-148
COOAKMDI_00099 1.2e-13 S Proteins of 100 residues with WXG
COOAKMDI_00100 8.6e-66
COOAKMDI_00101 6.8e-133 KT Response regulator receiver domain protein
COOAKMDI_00102 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
COOAKMDI_00103 6.5e-66 cspB K 'Cold-shock' DNA-binding domain
COOAKMDI_00104 1.3e-162 S Protein of unknown function (DUF3027)
COOAKMDI_00105 2.8e-174 uspA T Belongs to the universal stress protein A family
COOAKMDI_00106 0.0 clpC O ATPase family associated with various cellular activities (AAA)
COOAKMDI_00107 5e-307 3.1.3.5 F 5'-nucleotidase, C-terminal domain
COOAKMDI_00108 7.9e-164 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
COOAKMDI_00109 1.4e-09
COOAKMDI_00111 1.5e-218 L PFAM Integrase catalytic
COOAKMDI_00112 2.6e-201 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COOAKMDI_00113 1.3e-284 S Psort location Cytoplasmic, score
COOAKMDI_00114 2.5e-142
COOAKMDI_00115 9.4e-124 L PFAM Integrase catalytic
COOAKMDI_00116 1.8e-137 L PFAM Integrase catalytic
COOAKMDI_00117 1.2e-172 rfbJ M Glycosyl transferase family 2
COOAKMDI_00118 7e-20 tnp7109-21 L Integrase core domain
COOAKMDI_00119 3.1e-20 tnp7109-21 L Integrase core domain
COOAKMDI_00120 2.2e-207 S Acyltransferase family
COOAKMDI_00121 2e-303
COOAKMDI_00122 0.0 wbbM M Glycosyl transferase family 8
COOAKMDI_00123 3.2e-170 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
COOAKMDI_00124 2.7e-133 rgpC U Transport permease protein
COOAKMDI_00125 0.0 wbbM M Glycosyl transferase family 8
COOAKMDI_00126 1.5e-233 1.1.1.22 M UDP binding domain
COOAKMDI_00127 1.8e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COOAKMDI_00128 4.8e-179 I transferase activity, transferring acyl groups other than amino-acyl groups
COOAKMDI_00129 0.0 pflA S Protein of unknown function (DUF4012)
COOAKMDI_00130 5.3e-217 V ABC transporter permease
COOAKMDI_00131 2.6e-184 V ABC transporter
COOAKMDI_00133 6e-134 T HD domain
COOAKMDI_00134 1.3e-159 S Glutamine amidotransferase domain
COOAKMDI_00135 0.0 kup P Transport of potassium into the cell
COOAKMDI_00136 1e-184 tatD L TatD related DNase
COOAKMDI_00138 3.8e-154 lipA I Hydrolase, alpha beta domain protein
COOAKMDI_00139 1.1e-113 xylE U Sugar (and other) transporter
COOAKMDI_00140 4.2e-64 2.7.1.2 GK ROK family
COOAKMDI_00141 3.4e-89 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
COOAKMDI_00142 5.5e-28 K helix_turn_helix, arabinose operon control protein
COOAKMDI_00143 3.2e-24 XK27_00240 K Fic/DOC family
COOAKMDI_00144 5.5e-16 L HTH-like domain
COOAKMDI_00145 2.6e-197 S Fic/DOC family
COOAKMDI_00146 0.0 yknV V ABC transporter
COOAKMDI_00147 0.0 mdlA2 V ABC transporter
COOAKMDI_00148 3.9e-270 S ATPase domain predominantly from Archaea
COOAKMDI_00149 2.4e-42 S Domain of unknown function (DUF4143)
COOAKMDI_00150 9.3e-186 G Glycosyl hydrolases family 43
COOAKMDI_00151 1.1e-153 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_00152 1.2e-177 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_00153 5.2e-242 G Bacterial extracellular solute-binding protein
COOAKMDI_00154 1.9e-197 K helix_turn _helix lactose operon repressor
COOAKMDI_00155 0.0 lacZ 3.2.1.23 G Beta-galactosidase trimerisation domain
COOAKMDI_00156 1.2e-266 S AAA domain
COOAKMDI_00157 3.5e-250 EGP Major Facilitator Superfamily
COOAKMDI_00159 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
COOAKMDI_00160 0.0 oppD P Belongs to the ABC transporter superfamily
COOAKMDI_00161 9.2e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
COOAKMDI_00162 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
COOAKMDI_00163 1.6e-277 pepC 3.4.22.40 E Peptidase C1-like family
COOAKMDI_00164 2.8e-45
COOAKMDI_00166 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COOAKMDI_00167 4.7e-114
COOAKMDI_00168 1.8e-182 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COOAKMDI_00171 2.2e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
COOAKMDI_00172 1.9e-58 J TM2 domain
COOAKMDI_00173 1.4e-186 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
COOAKMDI_00174 1.3e-07
COOAKMDI_00175 2.4e-27 ganB 3.2.1.89 G Glycosyl hydrolase family 53
COOAKMDI_00176 9.6e-27 ganB 3.2.1.89 G Glycosyl hydrolase family 53
COOAKMDI_00177 1.9e-18 ganB 3.2.1.89 G Glycosyl hydrolase family 53
COOAKMDI_00178 1.2e-163 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
COOAKMDI_00179 3.7e-134 L Protein of unknown function (DUF1524)
COOAKMDI_00180 8.8e-219 mntH P H( )-stimulated, divalent metal cation uptake system
COOAKMDI_00181 3.3e-260 EGP Major facilitator Superfamily
COOAKMDI_00182 2.9e-132 S AAA ATPase domain
COOAKMDI_00183 1.5e-146 S Psort location Cytoplasmic, score 7.50
COOAKMDI_00184 1.5e-20 V efflux transmembrane transporter activity
COOAKMDI_00185 8.7e-161 L Transposase and inactivated derivatives IS30 family
COOAKMDI_00186 1e-82 L Phage integrase family
COOAKMDI_00187 4.3e-19
COOAKMDI_00188 7.3e-22
COOAKMDI_00189 1.6e-07 L Phage integrase family
COOAKMDI_00190 3.7e-15
COOAKMDI_00193 6.1e-252 yhjE EGP Sugar (and other) transporter
COOAKMDI_00194 8.8e-290 scrT G Transporter major facilitator family protein
COOAKMDI_00195 6.7e-300 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
COOAKMDI_00196 3.5e-202 K helix_turn _helix lactose operon repressor
COOAKMDI_00197 8.7e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COOAKMDI_00198 1.1e-123 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COOAKMDI_00199 2.4e-281 clcA P Voltage gated chloride channel
COOAKMDI_00200 5.8e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COOAKMDI_00201 1e-43 D AAA domain, putative AbiEii toxin, Type IV TA system
COOAKMDI_00202 1.8e-206 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
COOAKMDI_00203 4.9e-119 mug 3.2.2.28, 6.3.3.2 L Uracil DNA glycosylase superfamily
COOAKMDI_00204 1.3e-09 L Transposase DDE domain
COOAKMDI_00205 2.9e-83 Q Isochorismatase family
COOAKMDI_00206 1.7e-247 U Permease for cytosine/purines, uracil, thiamine, allantoin
COOAKMDI_00207 8.3e-99 yegV G pfkB family carbohydrate kinase
COOAKMDI_00208 9.6e-141 yegU O ADP-ribosylglycohydrolase
COOAKMDI_00209 3.2e-34 K UTRA
COOAKMDI_00210 3.5e-20 L Transposase and inactivated derivatives IS30 family
COOAKMDI_00211 1e-72 S Domain of unknown function (DUF4411)
COOAKMDI_00212 2.8e-128 E IrrE N-terminal-like domain
COOAKMDI_00213 1.1e-206 EGP Major Facilitator Superfamily
COOAKMDI_00215 5.3e-116 3.2.1.4 GH5,GH9 S acid phosphatase activity
COOAKMDI_00216 8.6e-150 htpX O Belongs to the peptidase M48B family
COOAKMDI_00217 1.2e-269 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
COOAKMDI_00219 8.9e-92 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COOAKMDI_00220 2.4e-99 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
COOAKMDI_00221 7.5e-80 ureF J Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COOAKMDI_00222 1.7e-87 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
COOAKMDI_00223 9.6e-303 ureC 3.5.1.5 E Urease alpha-subunit, N-terminal domain
COOAKMDI_00224 1.4e-95 ureB 3.5.1.5 E Urease, gamma subunit
COOAKMDI_00225 3.9e-110 hoxN S rRNA processing
COOAKMDI_00226 1.3e-99 urtE E ABC transporter
COOAKMDI_00227 2e-113 urtD S Branched-chain amino acid ATP-binding cassette transporter
COOAKMDI_00228 3.4e-160 urtC U Branched-chain amino acid transport system / permease component
COOAKMDI_00229 2.5e-129 urtB U Branched-chain amino acid transport system / permease component
COOAKMDI_00230 4.5e-196 urtA E Receptor family ligand binding region
COOAKMDI_00231 0.0 cadA P E1-E2 ATPase
COOAKMDI_00232 2.4e-247 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
COOAKMDI_00233 7.7e-260 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COOAKMDI_00235 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00236 5e-117 L Transposase, Mutator family
COOAKMDI_00237 3.2e-41 L Helix-turn-helix domain
COOAKMDI_00238 2.1e-101 V ATPases associated with a variety of cellular activities
COOAKMDI_00239 4.8e-173
COOAKMDI_00240 2.8e-26 V ABC-2 family transporter protein
COOAKMDI_00241 3.8e-90 mutF V ABC transporter ATP-binding
COOAKMDI_00242 6.2e-33 S ABC-2 family transporter protein
COOAKMDI_00243 9.6e-58 spaG S Lantibiotic protection ABC transporter permease subunit, MutG family
COOAKMDI_00244 5.1e-89
COOAKMDI_00245 1.2e-87 T Transcriptional regulatory protein, C terminal
COOAKMDI_00246 3.8e-118 T PhoQ Sensor
COOAKMDI_00247 2.5e-88
COOAKMDI_00248 3.2e-159 EG EamA-like transporter family
COOAKMDI_00249 2.7e-70 pdxH S Pfam:Pyridox_oxidase
COOAKMDI_00250 1.5e-236 L ribosomal rna small subunit methyltransferase
COOAKMDI_00251 6.9e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
COOAKMDI_00252 6.3e-171 corA P CorA-like Mg2+ transporter protein
COOAKMDI_00253 3.2e-150 ET Bacterial periplasmic substrate-binding proteins
COOAKMDI_00254 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COOAKMDI_00255 7e-58 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
COOAKMDI_00256 1.3e-251 comE S Competence protein
COOAKMDI_00257 4.6e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
COOAKMDI_00258 1.4e-101 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
COOAKMDI_00259 5.3e-150 yeaZ 2.3.1.234 O Glycoprotease family
COOAKMDI_00260 3.4e-98 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
COOAKMDI_00261 1.8e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COOAKMDI_00264 1.1e-103 M Peptidase family M23
COOAKMDI_00265 6.4e-256 G ABC transporter substrate-binding protein
COOAKMDI_00266 1.5e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
COOAKMDI_00267 5.3e-209 guaB 1.1.1.205 F IMP dehydrogenase family protein
COOAKMDI_00268 1.5e-70
COOAKMDI_00269 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
COOAKMDI_00270 1.3e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COOAKMDI_00271 6e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
COOAKMDI_00272 1.7e-138 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COOAKMDI_00273 4.2e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COOAKMDI_00274 5.4e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COOAKMDI_00275 2.1e-169 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
COOAKMDI_00276 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00277 5.7e-09 S Unextendable partial coding region
COOAKMDI_00278 2.3e-148 K Bacterial transcriptional regulator
COOAKMDI_00279 1e-131 hmgR K Sugar-specific transcriptional regulator TrmB
COOAKMDI_00280 1.6e-141 QT PucR C-terminal helix-turn-helix domain
COOAKMDI_00281 0.0
COOAKMDI_00282 1.8e-143 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
COOAKMDI_00283 4.3e-93 bioY S BioY family
COOAKMDI_00284 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
COOAKMDI_00285 9.4e-292 pccB I Carboxyl transferase domain
COOAKMDI_00286 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
COOAKMDI_00287 3.1e-153 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
COOAKMDI_00288 1.6e-150 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_00289 6.2e-145 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_00290 1.1e-205 msmE G transport
COOAKMDI_00291 1e-97 K helix_turn _helix lactose operon repressor
COOAKMDI_00292 1.3e-88 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COOAKMDI_00293 7.9e-217 L Transposase, Mutator family
COOAKMDI_00294 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00297 2.6e-291 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COOAKMDI_00299 7.3e-60 S Protein of unknown function (DUF805)
COOAKMDI_00300 1.8e-122 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
COOAKMDI_00301 1.9e-119
COOAKMDI_00302 3e-119 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
COOAKMDI_00303 2.3e-257 EGP Major facilitator Superfamily
COOAKMDI_00304 4.9e-204 rnr 3.6.4.12 K Putative DNA-binding domain
COOAKMDI_00305 2.4e-95 S GtrA-like protein
COOAKMDI_00306 5.1e-62 S Macrophage migration inhibitory factor (MIF)
COOAKMDI_00307 2.2e-290 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
COOAKMDI_00308 0.0 pepD E Peptidase family C69
COOAKMDI_00309 5.6e-106 S Phosphatidylethanolamine-binding protein
COOAKMDI_00310 2.8e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COOAKMDI_00312 3.3e-37 ptsH G PTS HPr component phosphorylation site
COOAKMDI_00313 1.7e-100 K helix_turn _helix lactose operon repressor
COOAKMDI_00314 9.9e-203 holB 2.7.7.7 L DNA polymerase III
COOAKMDI_00315 3.4e-121 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COOAKMDI_00316 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COOAKMDI_00317 5.6e-167 3.6.1.27 I PAP2 superfamily
COOAKMDI_00318 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00319 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COOAKMDI_00320 1.4e-37 K 'Cold-shock' DNA-binding domain
COOAKMDI_00321 7e-71 S LytR cell envelope-related transcriptional attenuator
COOAKMDI_00322 7.9e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COOAKMDI_00323 1.4e-190 moxR S ATPase family associated with various cellular activities (AAA)
COOAKMDI_00324 4.1e-170 S Protein of unknown function DUF58
COOAKMDI_00325 1.4e-85
COOAKMDI_00326 6.1e-183 S von Willebrand factor (vWF) type A domain
COOAKMDI_00327 1.1e-163 S von Willebrand factor (vWF) type A domain
COOAKMDI_00328 1.3e-44
COOAKMDI_00329 4.7e-47
COOAKMDI_00330 1.1e-305 S PGAP1-like protein
COOAKMDI_00331 8e-13
COOAKMDI_00332 5e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
COOAKMDI_00333 0.0 S Lysylphosphatidylglycerol synthase TM region
COOAKMDI_00334 6.2e-42 hup L Belongs to the bacterial histone-like protein family
COOAKMDI_00335 2.7e-25 L HTH-like domain
COOAKMDI_00337 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00338 6.5e-113 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
COOAKMDI_00339 0.0 tetP J Elongation factor G, domain IV
COOAKMDI_00340 2.6e-120 ypfH S Phospholipase/Carboxylesterase
COOAKMDI_00341 6.4e-98 papP E Binding-protein-dependent transport system inner membrane component
COOAKMDI_00342 5.7e-110 glnP E Binding-protein-dependent transport system inner membrane component
COOAKMDI_00343 4.1e-115 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
COOAKMDI_00344 3.6e-128 cjaA ET Bacterial periplasmic substrate-binding proteins
COOAKMDI_00345 8.3e-224 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
COOAKMDI_00346 2.5e-42 XAC3035 O Glutaredoxin
COOAKMDI_00347 3.1e-155 E Glyoxalase-like domain
COOAKMDI_00348 5e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COOAKMDI_00349 3.5e-199 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
COOAKMDI_00350 9.9e-219 E Receptor family ligand binding region
COOAKMDI_00351 0.0 E Branched-chain amino acid transport system / permease component
COOAKMDI_00352 0.0 E ATPases associated with a variety of cellular activities
COOAKMDI_00353 3.8e-229 S Peptidase dimerisation domain
COOAKMDI_00354 1.1e-242 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
COOAKMDI_00355 1.9e-138 3.6.3.21 E ATPases associated with a variety of cellular activities
COOAKMDI_00356 4e-142 tcyA ET Bacterial periplasmic substrate-binding proteins
COOAKMDI_00357 4.3e-110 E Binding-protein-dependent transport system inner membrane component
COOAKMDI_00358 7.3e-108 XK27_08050 O prohibitin homologues
COOAKMDI_00359 3e-203 S Domain of unknown function (DUF4143)
COOAKMDI_00360 1.3e-63 V ABC transporter
COOAKMDI_00361 7.1e-12 puuP_1 E Amino acid permease
COOAKMDI_00362 1.1e-23 puuP_1 E Amino acid permease
COOAKMDI_00363 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00365 1e-70 rplI J Binds to the 23S rRNA
COOAKMDI_00366 2.6e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COOAKMDI_00367 3.8e-74 ssb1 L Single-stranded DNA-binding protein
COOAKMDI_00368 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
COOAKMDI_00369 2.6e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COOAKMDI_00370 8.1e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COOAKMDI_00371 0.0 ubiB S ABC1 family
COOAKMDI_00372 1e-31 S granule-associated protein
COOAKMDI_00373 3.7e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
COOAKMDI_00374 6e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
COOAKMDI_00375 8.5e-257 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COOAKMDI_00376 4.3e-224 dinF V MatE
COOAKMDI_00377 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
COOAKMDI_00378 1e-54 glnB K Nitrogen regulatory protein P-II
COOAKMDI_00379 6.9e-229 amt U Ammonium Transporter Family
COOAKMDI_00380 1.4e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COOAKMDI_00381 1.5e-09
COOAKMDI_00382 1.1e-44 S Protein of unknown function (DUF2089)
COOAKMDI_00383 5.6e-124 icaR K Bacterial regulatory proteins, tetR family
COOAKMDI_00384 1.2e-186 XK27_01805 M Glycosyltransferase like family 2
COOAKMDI_00385 1.7e-264 pepD E Peptidase family C69
COOAKMDI_00386 4e-12
COOAKMDI_00387 1.2e-17 2.7.13.3 T Histidine kinase
COOAKMDI_00388 1.6e-35 K helix_turn_helix, Lux Regulon
COOAKMDI_00389 1.1e-48 EGP Transmembrane secretion effector
COOAKMDI_00391 4.5e-39
COOAKMDI_00392 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00394 1.5e-299 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COOAKMDI_00395 3.1e-192 opcA G Glucose-6-phosphate dehydrogenase subunit
COOAKMDI_00396 7.1e-150 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
COOAKMDI_00397 1.6e-271 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COOAKMDI_00398 5.1e-232 S Putative ABC-transporter type IV
COOAKMDI_00399 0.0 pip S YhgE Pip domain protein
COOAKMDI_00400 3.9e-309 pip S YhgE Pip domain protein
COOAKMDI_00401 5.8e-106 K Psort location Cytoplasmic, score 8.87
COOAKMDI_00402 2.8e-65 S FMN_bind
COOAKMDI_00403 2.2e-145 macB V ABC transporter, ATP-binding protein
COOAKMDI_00404 2.7e-214 Z012_06715 V FtsX-like permease family
COOAKMDI_00405 2.7e-212 macB_2 V ABC transporter permease
COOAKMDI_00406 5.4e-210 S Predicted membrane protein (DUF2318)
COOAKMDI_00407 7.9e-99 tpd P Fe2+ transport protein
COOAKMDI_00408 5.6e-237 efeU_1 P Iron permease FTR1 family
COOAKMDI_00412 1.5e-121 yoaK S Protein of unknown function (DUF1275)
COOAKMDI_00413 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
COOAKMDI_00414 1.4e-25
COOAKMDI_00415 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00416 1.3e-10 V Abi-like protein
COOAKMDI_00417 3.3e-17 L Helix-turn-helix domain
COOAKMDI_00418 5e-17 L Transposase and inactivated derivatives IS30 family
COOAKMDI_00420 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COOAKMDI_00421 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COOAKMDI_00422 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COOAKMDI_00423 2.3e-231 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COOAKMDI_00424 1.8e-125 tmp1 S Domain of unknown function (DUF4391)
COOAKMDI_00425 6.2e-143 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
COOAKMDI_00426 1e-182 MA20_14895 S Conserved hypothetical protein 698
COOAKMDI_00427 4.1e-62 S Psort location CytoplasmicMembrane, score
COOAKMDI_00428 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COOAKMDI_00429 7.1e-87 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COOAKMDI_00430 1.3e-193 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
COOAKMDI_00431 9.7e-258 S Domain of unknown function (DUF4143)
COOAKMDI_00433 2.3e-95 effR K helix_turn_helix multiple antibiotic resistance protein
COOAKMDI_00434 1e-131 C FMN binding
COOAKMDI_00435 1.9e-83 S AAA domain
COOAKMDI_00436 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
COOAKMDI_00437 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
COOAKMDI_00438 3.3e-242 vbsD V MatE
COOAKMDI_00439 2.3e-122 magIII L endonuclease III
COOAKMDI_00440 1.2e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COOAKMDI_00441 8.1e-44 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COOAKMDI_00442 1.4e-179 S Membrane transport protein
COOAKMDI_00443 4.2e-100 uidA 3.2.1.31 G Glycosyl hydrolases family 2, TIM barrel domain
COOAKMDI_00444 1.8e-278 glnA 6.3.1.2 E glutamine synthetase
COOAKMDI_00445 2.6e-138 S Domain of unknown function (DUF4191)
COOAKMDI_00446 4.9e-279 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COOAKMDI_00447 2.4e-110 S Protein of unknown function (DUF3043)
COOAKMDI_00448 1.5e-258 argE E Peptidase dimerisation domain
COOAKMDI_00449 3.1e-107 ykoE S ABC-type cobalt transport system, permease component
COOAKMDI_00450 1.3e-271 ykoD P ATPases associated with a variety of cellular activities
COOAKMDI_00451 6.5e-148 cbiQ P Cobalt transport protein
COOAKMDI_00452 1e-159 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COOAKMDI_00453 1.9e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COOAKMDI_00454 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
COOAKMDI_00455 1.1e-95
COOAKMDI_00456 1.6e-202 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
COOAKMDI_00457 7.4e-214 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
COOAKMDI_00458 4.1e-167 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
COOAKMDI_00459 3e-248 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
COOAKMDI_00460 9.5e-183 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COOAKMDI_00461 3.6e-80 argR K Regulates arginine biosynthesis genes
COOAKMDI_00462 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
COOAKMDI_00463 6.8e-281 argH 4.3.2.1 E argininosuccinate lyase
COOAKMDI_00464 2.1e-28 thiS 2.8.1.10 H ThiS family
COOAKMDI_00465 3.1e-156 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
COOAKMDI_00466 1.3e-145 moeB 2.7.7.80 H ThiF family
COOAKMDI_00467 8.7e-57 M1-798 P Rhodanese Homology Domain
COOAKMDI_00468 2.1e-99 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
COOAKMDI_00469 1.9e-138 S Putative ABC-transporter type IV
COOAKMDI_00470 7.5e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COOAKMDI_00471 7e-131 L Tetratricopeptide repeat
COOAKMDI_00472 1.5e-194 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
COOAKMDI_00474 3e-139 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
COOAKMDI_00475 1e-98
COOAKMDI_00476 1.6e-94 trkA P TrkA-N domain
COOAKMDI_00477 9.3e-108 L Transposase and inactivated derivatives
COOAKMDI_00478 3.8e-29 L transposase activity
COOAKMDI_00479 2.8e-14 trkA P TrkA-N domain
COOAKMDI_00480 8.3e-263 trkB P Cation transport protein
COOAKMDI_00481 5.2e-187 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COOAKMDI_00482 6.6e-310 recN L May be involved in recombinational repair of damaged DNA
COOAKMDI_00483 7.7e-120 S Haloacid dehalogenase-like hydrolase
COOAKMDI_00484 2.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
COOAKMDI_00485 2.5e-172 V ATPases associated with a variety of cellular activities
COOAKMDI_00486 1.6e-118 S ABC-2 family transporter protein
COOAKMDI_00487 4.1e-67 S ABC-2 family transporter protein
COOAKMDI_00488 8.8e-25 pacL2 3.6.3.8 P ATPase, P-type transporting, HAD superfamily, subfamily IC
COOAKMDI_00489 7.8e-71 K helix_turn_helix gluconate operon transcriptional repressor
COOAKMDI_00490 5.2e-196 S Protein of unknown function (DUF1648)
COOAKMDI_00491 7.3e-283 thrC 4.2.3.1 E Threonine synthase N terminus
COOAKMDI_00492 5.5e-250 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COOAKMDI_00493 3.7e-230 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COOAKMDI_00494 1.4e-99
COOAKMDI_00495 2.9e-137 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COOAKMDI_00496 1.6e-208 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
COOAKMDI_00497 0.0 S Uncharacterised protein family (UPF0182)
COOAKMDI_00498 5.9e-88 2.3.1.183 M Acetyltransferase (GNAT) domain
COOAKMDI_00499 2.7e-46 S RelB antitoxin
COOAKMDI_00500 1.6e-73 S PIN domain
COOAKMDI_00501 2e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COOAKMDI_00502 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COOAKMDI_00503 3.9e-181 1.1.1.65 C Aldo/keto reductase family
COOAKMDI_00504 4.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COOAKMDI_00505 3.1e-75 divIC D Septum formation initiator
COOAKMDI_00506 2.4e-101 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
COOAKMDI_00507 5.8e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
COOAKMDI_00509 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00510 5.9e-212 L Integrase core domain
COOAKMDI_00511 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00513 5.9e-103 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
COOAKMDI_00514 6.3e-168 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
COOAKMDI_00515 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
COOAKMDI_00516 1.2e-239 carA 6.3.5.5 F Belongs to the CarA family
COOAKMDI_00517 1.6e-76 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COOAKMDI_00518 1.2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COOAKMDI_00519 1.3e-113 ybbL V ATPases associated with a variety of cellular activities
COOAKMDI_00520 3.5e-74 ybbM V Uncharacterised protein family (UPF0014)
COOAKMDI_00521 0.0 G Glycosyl hydrolase family 20, domain 2
COOAKMDI_00522 1.1e-201 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
COOAKMDI_00523 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COOAKMDI_00524 0.0 S Tetratricopeptide repeat
COOAKMDI_00525 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COOAKMDI_00526 1.4e-139 bioM P ATPases associated with a variety of cellular activities
COOAKMDI_00527 1.9e-232 E Aminotransferase class I and II
COOAKMDI_00528 3.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
COOAKMDI_00529 2.9e-198 S Glycosyltransferase, group 2 family protein
COOAKMDI_00530 3.3e-102 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COOAKMDI_00531 0.0 ecfA GP ABC transporter, ATP-binding protein
COOAKMDI_00532 2.7e-46 yhbY J CRS1_YhbY
COOAKMDI_00533 6.7e-30 KT Replicase family
COOAKMDI_00534 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00535 2.4e-210 K Transposase IS116 IS110 IS902
COOAKMDI_00536 2.5e-57 L IstB-like ATP binding protein
COOAKMDI_00537 4.6e-68 V AAA domain, putative AbiEii toxin, Type IV TA system
COOAKMDI_00538 1.4e-16 S ABC-2 family transporter protein
COOAKMDI_00539 3.7e-180 yocS S SBF-like CPA transporter family (DUF4137)
COOAKMDI_00541 1e-187 ltaE 4.1.2.48 E Beta-eliminating lyase
COOAKMDI_00542 3.2e-209 M Glycosyl transferase 4-like domain
COOAKMDI_00543 1.7e-189 mtnE 2.6.1.83 E Aminotransferase class I and II
COOAKMDI_00544 6.2e-223 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COOAKMDI_00545 3.2e-62 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COOAKMDI_00546 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
COOAKMDI_00547 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
COOAKMDI_00548 2.7e-195 I alpha/beta hydrolase fold
COOAKMDI_00549 1e-254 Q D-alanine [D-alanyl carrier protein] ligase activity
COOAKMDI_00550 6.2e-109 Q D-alanine [D-alanyl carrier protein] ligase activity
COOAKMDI_00551 2.9e-99 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
COOAKMDI_00552 1.1e-169 hipA 2.7.11.1 S HipA N-terminal domain
COOAKMDI_00553 5.4e-10 C Aldo/keto reductase family
COOAKMDI_00554 2e-47 C Aldo/keto reductase family
COOAKMDI_00555 3.5e-32
COOAKMDI_00556 1.1e-274 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
COOAKMDI_00557 7.8e-192 3.3.1.1 H S-adenosyl-L-homocysteine hydrolase, NAD binding domain
COOAKMDI_00558 2.7e-239 ssnA 3.5.4.40 F Amidohydrolase family
COOAKMDI_00559 1.8e-65 MA20_39615 S Cupin superfamily (DUF985)
COOAKMDI_00560 1.7e-127 ET Bacterial periplasmic substrate-binding proteins
COOAKMDI_00561 5.3e-122 E Binding-protein-dependent transport system inner membrane component
COOAKMDI_00562 6.4e-121 glnQ 3.6.3.21 E AAA domain, putative AbiEii toxin, Type IV TA system
COOAKMDI_00563 7.7e-288 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COOAKMDI_00564 1.2e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COOAKMDI_00565 1.9e-231 purD 6.3.4.13 F Belongs to the GARS family
COOAKMDI_00566 9.3e-271 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
COOAKMDI_00567 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
COOAKMDI_00568 1.2e-147 P Zinc-uptake complex component A periplasmic
COOAKMDI_00569 1.4e-99 S cobalamin synthesis protein
COOAKMDI_00570 3.9e-29 rpmB J Ribosomal L28 family
COOAKMDI_00571 1.4e-20 rpmG J Ribosomal protein L33
COOAKMDI_00572 2.5e-44 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COOAKMDI_00573 4.4e-34 rpmE2 J Ribosomal protein L31
COOAKMDI_00574 7e-14 rpmJ J Ribosomal protein L36
COOAKMDI_00575 2.6e-19 J Ribosomal L32p protein family
COOAKMDI_00576 1.3e-33 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
COOAKMDI_00577 6.7e-172 ycgR S Predicted permease
COOAKMDI_00578 4.3e-138 S TIGRFAM TIGR03943 family protein
COOAKMDI_00579 4e-84 zur P Ferric uptake regulator family
COOAKMDI_00580 1.1e-51
COOAKMDI_00581 7.6e-46 tetR K Transcriptional regulator C-terminal region
COOAKMDI_00582 2.1e-68 XK27_06785 V ABC transporter
COOAKMDI_00583 1.4e-26 ylbB V FtsX-like permease family
COOAKMDI_00585 6.4e-50 ylbB V FtsX-like permease family
COOAKMDI_00586 1.2e-68 zur P Belongs to the Fur family
COOAKMDI_00587 4.2e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COOAKMDI_00588 7.3e-86 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COOAKMDI_00589 4.7e-177 adh3 C Zinc-binding dehydrogenase
COOAKMDI_00590 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COOAKMDI_00591 8.3e-253 macB_8 V MacB-like periplasmic core domain
COOAKMDI_00592 3.9e-122 M Conserved repeat domain
COOAKMDI_00593 2.8e-129 V ATPases associated with a variety of cellular activities
COOAKMDI_00595 1.8e-215 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
COOAKMDI_00596 5.8e-155 K Helix-turn-helix domain, rpiR family
COOAKMDI_00597 0.0 G Alpha-L-arabinofuranosidase C-terminal domain
COOAKMDI_00598 2.6e-28
COOAKMDI_00599 1.2e-15 ybiR P Citrate transporter
COOAKMDI_00600 0.0 EK Alanine-glyoxylate amino-transferase
COOAKMDI_00601 1.2e-114 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
COOAKMDI_00602 3.4e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
COOAKMDI_00603 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COOAKMDI_00604 5.1e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
COOAKMDI_00605 5.7e-250 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COOAKMDI_00606 1.6e-266 yhdG E aromatic amino acid transport protein AroP K03293
COOAKMDI_00607 6.7e-101 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COOAKMDI_00608 4.7e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COOAKMDI_00609 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
COOAKMDI_00610 6.5e-296 enhA_2 S L,D-transpeptidase catalytic domain
COOAKMDI_00611 1.2e-222 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
COOAKMDI_00612 7e-91 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
COOAKMDI_00614 2.1e-170 EGP Major Facilitator Superfamily
COOAKMDI_00615 2.1e-150 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
COOAKMDI_00616 9.6e-117 sapF E ATPases associated with a variety of cellular activities
COOAKMDI_00617 1.1e-121 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
COOAKMDI_00618 6.7e-125 EP Binding-protein-dependent transport system inner membrane component
COOAKMDI_00619 4.6e-161 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_00620 2.4e-282 E ABC transporter, substrate-binding protein, family 5
COOAKMDI_00621 1.4e-245 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COOAKMDI_00622 9.3e-141 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
COOAKMDI_00623 4.2e-264 G Bacterial extracellular solute-binding protein
COOAKMDI_00624 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
COOAKMDI_00625 2.1e-113 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
COOAKMDI_00626 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COOAKMDI_00627 1.1e-147 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
COOAKMDI_00628 1.3e-150 yecS E Binding-protein-dependent transport system inner membrane component
COOAKMDI_00629 1.4e-159 pknD ET ABC transporter, substrate-binding protein, family 3
COOAKMDI_00630 6.8e-141 pknD ET ABC transporter, substrate-binding protein, family 3
COOAKMDI_00631 1.8e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COOAKMDI_00632 1.9e-51 usp 3.5.1.28 CBM50 D CHAP domain protein
COOAKMDI_00633 2.4e-210 K Transposase IS116 IS110 IS902
COOAKMDI_00634 9.9e-130 L IstB-like ATP binding protein
COOAKMDI_00635 2.3e-268 L PFAM Integrase catalytic
COOAKMDI_00637 2.1e-117 S EamA-like transporter family
COOAKMDI_00638 2.4e-210 K Transposase IS116 IS110 IS902
COOAKMDI_00639 4.5e-16
COOAKMDI_00640 1.1e-71 yycO S PFAM Orthopoxvirus protein of
COOAKMDI_00641 9.7e-42
COOAKMDI_00642 1.2e-178 tnp7109-2 L Transposase, Mutator family
COOAKMDI_00643 5.2e-34 L Transposase and inactivated derivatives IS30 family
COOAKMDI_00644 3.7e-17
COOAKMDI_00647 1.9e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COOAKMDI_00648 1.3e-196 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COOAKMDI_00649 2.8e-131 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
COOAKMDI_00650 2e-80 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COOAKMDI_00651 4.3e-26 rpmI J Ribosomal protein L35
COOAKMDI_00652 1.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COOAKMDI_00653 2.8e-168 xerD D recombinase XerD
COOAKMDI_00654 0.0 macB_2 V ATPases associated with a variety of cellular activities
COOAKMDI_00655 1.7e-149 soj D CobQ CobB MinD ParA nucleotide binding domain protein
COOAKMDI_00656 2.2e-160 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COOAKMDI_00657 1e-120 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COOAKMDI_00658 1e-153 nrtR 3.6.1.55 F NUDIX hydrolase
COOAKMDI_00659 8.3e-251 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
COOAKMDI_00660 1.1e-300 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
COOAKMDI_00661 2.3e-162 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
COOAKMDI_00662 3.7e-219 iscS1 2.8.1.7 E Aminotransferase class-V
COOAKMDI_00663 1.2e-244 naiP U Sugar (and other) transporter
COOAKMDI_00664 0.0 typA T Elongation factor G C-terminus
COOAKMDI_00665 2e-74
COOAKMDI_00666 1.5e-191 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
COOAKMDI_00667 5e-193 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
COOAKMDI_00668 2e-42
COOAKMDI_00669 6.1e-183 xerC D Belongs to the 'phage' integrase family. XerC subfamily
COOAKMDI_00670 4.5e-311 E ABC transporter, substrate-binding protein, family 5
COOAKMDI_00671 1.7e-152 dppB EP Binding-protein-dependent transport system inner membrane component
COOAKMDI_00672 3.9e-171 dppC EP N-terminal TM domain of oligopeptide transport permease C
COOAKMDI_00673 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
COOAKMDI_00674 1.7e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
COOAKMDI_00675 1.4e-137 S Protein of unknown function (DUF3710)
COOAKMDI_00676 4.6e-135 S Protein of unknown function (DUF3159)
COOAKMDI_00677 1.7e-240 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COOAKMDI_00678 3.4e-105
COOAKMDI_00679 0.0 ctpE P E1-E2 ATPase
COOAKMDI_00680 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
COOAKMDI_00681 1.4e-57 relB L RelB antitoxin
COOAKMDI_00682 7.9e-85 S PIN domain
COOAKMDI_00683 0.0 S Protein of unknown function DUF262
COOAKMDI_00684 1.4e-116 E Psort location Cytoplasmic, score 8.87
COOAKMDI_00685 5.9e-126 ybhL S Belongs to the BI1 family
COOAKMDI_00686 5.4e-173 ydeD EG EamA-like transporter family
COOAKMDI_00687 1.3e-135 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
COOAKMDI_00688 6.4e-173 L Transposase, Mutator family
COOAKMDI_00692 7.3e-13 1.3.99.36, 4.1.1.36, 6.3.2.5 H Flavoprotein
COOAKMDI_00694 1.4e-11 repC K PFAM O-methyltransferase
COOAKMDI_00695 1e-67 ydiF S ATPases associated with a variety of cellular activities
COOAKMDI_00696 2.4e-58 L Transposase and inactivated derivatives IS30 family
COOAKMDI_00697 1.4e-40 ptsH G phosphoenolpyruvate-dependent sugar phosphotransferase system
COOAKMDI_00698 1.7e-291 ptsP 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COOAKMDI_00699 2.1e-126 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
COOAKMDI_00700 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
COOAKMDI_00701 2.1e-42 csoR S Metal-sensitive transcriptional repressor
COOAKMDI_00702 5e-188 rmuC S RmuC family
COOAKMDI_00703 4.7e-98 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COOAKMDI_00704 9.3e-158 spoU 2.1.1.185 J RNA methyltransferase TrmH family
COOAKMDI_00705 3.5e-185 K Psort location Cytoplasmic, score
COOAKMDI_00706 2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COOAKMDI_00707 1.1e-286 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COOAKMDI_00708 7.9e-285 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COOAKMDI_00709 5.2e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
COOAKMDI_00710 3.3e-52 S Protein of unknown function (DUF2469)
COOAKMDI_00711 5.7e-285 S Histidine phosphatase superfamily (branch 2)
COOAKMDI_00712 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
COOAKMDI_00713 2.3e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COOAKMDI_00715 2e-62 tyrA 5.4.99.5 E Chorismate mutase type II
COOAKMDI_00716 1.8e-295 S domain protein
COOAKMDI_00717 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00718 1.8e-63 V Abi-like protein
COOAKMDI_00719 2.4e-210 K Transposase IS116 IS110 IS902
COOAKMDI_00720 3.7e-41 S Prophage endopeptidase tail
COOAKMDI_00723 1.5e-39
COOAKMDI_00724 1.8e-130
COOAKMDI_00725 1.1e-85 L reverse transcriptase
COOAKMDI_00727 4.7e-17
COOAKMDI_00728 8.3e-107 M Glycosyl hydrolases family 25
COOAKMDI_00729 2.2e-28 S Putative phage holin Dp-1
COOAKMDI_00730 7.2e-38
COOAKMDI_00731 2.4e-43 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
COOAKMDI_00732 3.2e-94 L Phage integrase family
COOAKMDI_00735 6.1e-13
COOAKMDI_00736 6.5e-23 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
COOAKMDI_00737 4.2e-205 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
COOAKMDI_00738 5.1e-145 atpB C it plays a direct role in the translocation of protons across the membrane
COOAKMDI_00739 1.5e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COOAKMDI_00740 2.7e-59 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COOAKMDI_00741 1.2e-144 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COOAKMDI_00742 1.7e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COOAKMDI_00743 5.4e-159 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COOAKMDI_00744 4.4e-280 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COOAKMDI_00745 1.6e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COOAKMDI_00746 1.9e-133 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
COOAKMDI_00747 5.4e-157 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
COOAKMDI_00748 3e-185
COOAKMDI_00749 1.9e-181
COOAKMDI_00750 3.1e-165 trxA2 O Tetratricopeptide repeat
COOAKMDI_00751 2.6e-117 cyaA 4.6.1.1 S CYTH
COOAKMDI_00753 1.4e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
COOAKMDI_00754 1.3e-182 plsC2 2.3.1.51 I Phosphate acyltransferases
COOAKMDI_00755 3.2e-181 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
COOAKMDI_00756 7.7e-227 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COOAKMDI_00757 6.2e-213 P Bacterial extracellular solute-binding protein
COOAKMDI_00758 1.5e-156 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_00759 8.3e-130 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_00760 4.3e-223 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COOAKMDI_00761 5.4e-176 S CAAX protease self-immunity
COOAKMDI_00762 3.6e-127 M Mechanosensitive ion channel
COOAKMDI_00763 6.8e-270 aspA 4.3.1.1 E Fumarase C C-terminus
COOAKMDI_00764 7.3e-135 K Bacterial regulatory proteins, tetR family
COOAKMDI_00765 2.5e-240 MA20_36090 S Psort location Cytoplasmic, score 8.87
COOAKMDI_00766 1.7e-87 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COOAKMDI_00767 1.7e-10 XK27_04590 S NADPH-dependent FMN reductase
COOAKMDI_00772 4.4e-21 yxiO G Major facilitator Superfamily
COOAKMDI_00773 1.2e-52 relB L RelB antitoxin
COOAKMDI_00774 6.3e-69 T Toxic component of a toxin-antitoxin (TA) module
COOAKMDI_00775 2.2e-131 K helix_turn_helix, mercury resistance
COOAKMDI_00776 5.9e-233 yxiO S Vacuole effluxer Atg22 like
COOAKMDI_00777 1.2e-196 yegV G pfkB family carbohydrate kinase
COOAKMDI_00778 5.5e-29 rpmB J Ribosomal L28 family
COOAKMDI_00779 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
COOAKMDI_00780 2.5e-90 steT E amino acid
COOAKMDI_00781 8.5e-72 K Bacterial regulatory proteins, lacI family
COOAKMDI_00782 1.4e-159 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_00783 8.2e-174 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_00784 1.8e-67 S phage tail
COOAKMDI_00785 4.2e-83 NT phage tail tape measure protein
COOAKMDI_00786 1.3e-29
COOAKMDI_00787 7.6e-28
COOAKMDI_00788 8.1e-60 eae N domain, Protein
COOAKMDI_00789 1e-20
COOAKMDI_00791 4.5e-31
COOAKMDI_00792 7.9e-47 S Phage protein Gp19/Gp15/Gp42
COOAKMDI_00794 1.5e-145 V Phage capsid family
COOAKMDI_00795 7.4e-28
COOAKMDI_00796 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_00797 1.9e-16 S Protein of unknown function (DUF4230)
COOAKMDI_00798 9e-27 S Protein of unknown function (DUF4230)
COOAKMDI_00801 1.7e-199
COOAKMDI_00802 6e-110 V ABC transporter
COOAKMDI_00803 2.7e-07
COOAKMDI_00804 3.6e-43 2.7.13.3 T Histidine kinase
COOAKMDI_00805 1.3e-50 K helix_turn_helix, Lux Regulon
COOAKMDI_00807 2.8e-33 L Phage integrase family
COOAKMDI_00808 5.5e-63 V Abi-like protein
COOAKMDI_00809 4.2e-72 hsp20 O Hsp20/alpha crystallin family
COOAKMDI_00810 3.8e-127 yplQ S Haemolysin-III related
COOAKMDI_00811 2.7e-83 yjcF Q Acetyltransferase (GNAT) domain
COOAKMDI_00812 3.5e-52 ybjQ S Putative heavy-metal-binding
COOAKMDI_00813 4.4e-166 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
COOAKMDI_00814 3e-125 S Domain of unknown function (DUF4928)
COOAKMDI_00815 2.1e-129 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
COOAKMDI_00816 3.2e-161 M Glycosyltransferase like family 2
COOAKMDI_00817 3e-110 S Pyridoxamine 5'-phosphate oxidase
COOAKMDI_00818 1.3e-184 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COOAKMDI_00819 0.0 lysX S Uncharacterised conserved protein (DUF2156)
COOAKMDI_00820 1.7e-203 S Putative esterase
COOAKMDI_00821 7e-146 yddG EG EamA-like transporter family
COOAKMDI_00822 2.9e-204 pldB 3.1.1.5 I Serine aminopeptidase, S33
COOAKMDI_00823 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
COOAKMDI_00824 2.6e-129 fhaA T Protein of unknown function (DUF2662)
COOAKMDI_00825 8e-59 fhaB T Inner membrane component of T3SS, cytoplasmic domain
COOAKMDI_00826 1.8e-240 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
COOAKMDI_00827 1.6e-251 rodA D Belongs to the SEDS family
COOAKMDI_00828 2.3e-257 pbpA M penicillin-binding protein
COOAKMDI_00829 3.7e-171 T Protein tyrosine kinase
COOAKMDI_00830 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
COOAKMDI_00831 2.2e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
COOAKMDI_00832 2.5e-236 srtA 3.4.22.70 M Sortase family
COOAKMDI_00833 8.9e-110 S Bacterial protein of unknown function (DUF881)
COOAKMDI_00834 9.6e-80 crgA D Involved in cell division
COOAKMDI_00835 2.2e-125 gluP 3.4.21.105 S Rhomboid family
COOAKMDI_00836 1.7e-31
COOAKMDI_00837 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COOAKMDI_00838 1.7e-75 I Sterol carrier protein
COOAKMDI_00839 9.1e-235 EGP Major Facilitator Superfamily
COOAKMDI_00840 4.1e-209 2.7.13.3 T Histidine kinase
COOAKMDI_00841 9.4e-113 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COOAKMDI_00842 7.5e-38 S Protein of unknown function (DUF3073)
COOAKMDI_00843 1.2e-202 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
COOAKMDI_00844 3.1e-108 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
COOAKMDI_00845 1.1e-55 K Psort location Cytoplasmic, score
COOAKMDI_00846 3.5e-286 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COOAKMDI_00847 1.5e-98 EGP Major facilitator Superfamily
COOAKMDI_00848 2.2e-36 K helix_turn_helix, Arsenical Resistance Operon Repressor
COOAKMDI_00849 3.5e-66 C Radical SAM superfamily
COOAKMDI_00850 0.0 yjjP S Threonine/Serine exporter, ThrE
COOAKMDI_00851 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
COOAKMDI_00852 1.8e-38 ybfG M Domain of unknown function (DUF1906)
COOAKMDI_00853 1.4e-153 P Belongs to the ABC transporter superfamily
COOAKMDI_00854 2.5e-89 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COOAKMDI_00855 1.9e-122 appB P PFAM binding-protein-dependent transport systems inner membrane component
COOAKMDI_00856 1.3e-190 oppA5 E family 5
COOAKMDI_00857 9.9e-25 trxB1 1.8.1.9 C Thioredoxin domain
COOAKMDI_00858 2.9e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
COOAKMDI_00859 4.1e-231 S AAA domain
COOAKMDI_00860 5e-23 L PFAM Integrase catalytic
COOAKMDI_00861 5e-148 I alpha/beta hydrolase fold
COOAKMDI_00862 2.3e-231 M Protein of unknown function (DUF2961)
COOAKMDI_00863 2.3e-151 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_00864 1.6e-158 G Binding-protein-dependent transport system inner membrane component
COOAKMDI_00865 3.7e-254 G Bacterial extracellular solute-binding protein
COOAKMDI_00866 2.3e-187 K helix_turn _helix lactose operon repressor
COOAKMDI_00867 1e-298 M probably involved in cell wall
COOAKMDI_00868 0.0 S Glycosyl hydrolases related to GH101 family, GH129
COOAKMDI_00869 3.8e-309 E ABC transporter, substrate-binding protein, family 5
COOAKMDI_00870 2.8e-301 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
COOAKMDI_00871 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
COOAKMDI_00872 2e-178 K helix_turn _helix lactose operon repressor
COOAKMDI_00875 1.5e-134 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COOAKMDI_00876 5.4e-180 hemN H Involved in the biosynthesis of porphyrin-containing compound
COOAKMDI_00877 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COOAKMDI_00878 2.2e-33 rpsT J Binds directly to 16S ribosomal RNA
COOAKMDI_00879 1.7e-126 S UPF0126 domain
COOAKMDI_00880 3.8e-109 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
COOAKMDI_00881 4.3e-227 ilvE 2.6.1.42 E Amino-transferase class IV
COOAKMDI_00882 1.2e-82 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
COOAKMDI_00883 2.3e-198 S alpha beta
COOAKMDI_00884 1.9e-235 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
COOAKMDI_00885 1e-42 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
COOAKMDI_00886 1e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
COOAKMDI_00887 0.0 fadD 6.2.1.3 I AMP-binding enzyme
COOAKMDI_00888 2.3e-182 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COOAKMDI_00889 2.4e-254 corC S CBS domain
COOAKMDI_00890 6.8e-101 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COOAKMDI_00891 1.8e-212 phoH T PhoH-like protein
COOAKMDI_00892 1.5e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
COOAKMDI_00893 2.9e-145 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COOAKMDI_00895 1.2e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
COOAKMDI_00896 2.9e-240 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COOAKMDI_00897 2.7e-111 yitW S Iron-sulfur cluster assembly protein
COOAKMDI_00898 3.1e-101 iscU C SUF system FeS assembly protein, NifU family
COOAKMDI_00899 2.1e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COOAKMDI_00900 9.2e-144 sufC O FeS assembly ATPase SufC
COOAKMDI_00901 2.8e-235 sufD O FeS assembly protein SufD
COOAKMDI_00902 3.3e-291 sufB O FeS assembly protein SufB
COOAKMDI_00903 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COOAKMDI_00904 7e-80 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
COOAKMDI_00905 4.5e-311 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
COOAKMDI_00906 5.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
COOAKMDI_00907 4.5e-77 3.4.23.43 S Type IV leader peptidase family
COOAKMDI_00908 4.2e-201 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COOAKMDI_00909 8.7e-78 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COOAKMDI_00910 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COOAKMDI_00911 1.6e-35
COOAKMDI_00912 5.3e-63 WQ51_05790 S Bacterial protein of unknown function (DUF948)
COOAKMDI_00913 3.4e-126 pgm3 G Phosphoglycerate mutase family
COOAKMDI_00914 4.9e-30 L Transposase and inactivated derivatives IS30 family
COOAKMDI_00915 4.6e-48 relB L RelB antitoxin
COOAKMDI_00916 4.3e-64 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COOAKMDI_00917 6.1e-111 E Transglutaminase-like superfamily
COOAKMDI_00918 5.3e-46 sdpI S SdpI/YhfL protein family
COOAKMDI_00919 1.8e-89 3.5.4.5 F cytidine deaminase activity
COOAKMDI_00920 1.9e-149 S Peptidase C26
COOAKMDI_00921 2.2e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COOAKMDI_00922 1.2e-129 lolD V ABC transporter
COOAKMDI_00923 5.9e-212 L Integrase core domain
COOAKMDI_00924 1.1e-225 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
COOAKMDI_00925 1.2e-121 glpR K DeoR C terminal sensor domain
COOAKMDI_00926 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
COOAKMDI_00927 1.4e-231 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
COOAKMDI_00928 1.9e-43 gcvR T Belongs to the UPF0237 family
COOAKMDI_00929 1.2e-252 S UPF0210 protein
COOAKMDI_00930 2.9e-114 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COOAKMDI_00931 5.5e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
COOAKMDI_00932 1.3e-107
COOAKMDI_00933 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOAKMDI_00934 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOAKMDI_00935 8.7e-84 T Forkhead associated domain
COOAKMDI_00936 1.1e-70 B Belongs to the OprB family
COOAKMDI_00937 2.1e-25 3.1.3.16 T Sigma factor PP2C-like phosphatases
COOAKMDI_00938 0.0 E Transglutaminase-like superfamily
COOAKMDI_00939 6.3e-224 S Protein of unknown function DUF58
COOAKMDI_00940 6.2e-177 S ATPase family associated with various cellular activities (AAA)
COOAKMDI_00941 0.0 S Fibronectin type 3 domain
COOAKMDI_00942 9.2e-259 KLT Protein tyrosine kinase
COOAKMDI_00943 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
COOAKMDI_00944 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
COOAKMDI_00945 2.5e-226 G Major Facilitator Superfamily
COOAKMDI_00946 3e-131 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COOAKMDI_00947 1e-165 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COOAKMDI_00948 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COOAKMDI_00949 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
COOAKMDI_00950 1.2e-99 ugpQ 3.1.4.46 C Domain of unknown function
COOAKMDI_00951 1.2e-159 ugpB G Bacterial extracellular solute-binding protein
COOAKMDI_00952 1e-97 ugpE G Binding-protein-dependent transport system inner membrane component
COOAKMDI_00953 2.6e-97 ugpA P Binding-protein-dependent transport system inner membrane component
COOAKMDI_00954 1.7e-257 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COOAKMDI_00955 5.2e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COOAKMDI_00956 1e-273 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
COOAKMDI_00957 5e-254 S Domain of unknown function (DUF4143)
COOAKMDI_00958 9.3e-206 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COOAKMDI_00959 1.8e-175 ftsE D Cell division ATP-binding protein FtsE
COOAKMDI_00960 6.3e-160 ftsX D Part of the ABC transporter FtsEX involved in cellular division
COOAKMDI_00961 1.9e-29 usp 3.5.1.28 CBM50 D CHAP domain protein
COOAKMDI_00962 6.9e-11 KT Replicase family
COOAKMDI_00964 6.9e-11 KT Replicase family
COOAKMDI_00966 1.5e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
COOAKMDI_00967 4.7e-76 3.5.1.124 S DJ-1/PfpI family
COOAKMDI_00968 6.1e-140 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
COOAKMDI_00969 4.9e-69 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
COOAKMDI_00970 7.4e-294 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COOAKMDI_00971 6.3e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COOAKMDI_00972 3.4e-164 S Protein of unknown function (DUF979)
COOAKMDI_00973 1.2e-118 S Protein of unknown function (DUF969)
COOAKMDI_00974 1.2e-299 ybiT S ABC transporter
COOAKMDI_00975 1.4e-127 yueD S Enoyl-(Acyl carrier protein) reductase
COOAKMDI_00976 8.2e-162 2.1.1.72 S Protein conserved in bacteria
COOAKMDI_00977 9.6e-34 S Zincin-like metallopeptidase
COOAKMDI_00978 4.5e-51 G ATPases associated with a variety of cellular activities
COOAKMDI_00979 7.3e-13 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
COOAKMDI_00980 2e-123 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
COOAKMDI_00981 3.1e-116 K Transcriptional regulatory protein, C terminal
COOAKMDI_00982 3.5e-146
COOAKMDI_00983 1.8e-148 M Putative peptidoglycan binding domain
COOAKMDI_00984 1.4e-136 macB V ATPases associated with a variety of cellular activities
COOAKMDI_00985 1.3e-165 V MacB-like periplasmic core domain
COOAKMDI_00986 5.3e-295 S Psort location Cytoplasmic, score 8.87
COOAKMDI_00987 2.7e-112 S Domain of unknown function (DUF4194)
COOAKMDI_00988 0.0 S Psort location Cytoplasmic, score 8.87
COOAKMDI_00989 2.3e-24 S Psort location Cytoplasmic, score 8.87
COOAKMDI_00990 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COOAKMDI_00991 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COOAKMDI_00992 2.5e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
COOAKMDI_00993 6.7e-184 rapZ S Displays ATPase and GTPase activities
COOAKMDI_00994 1.2e-169 whiA K May be required for sporulation
COOAKMDI_00995 3.5e-219 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
COOAKMDI_00996 4.2e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COOAKMDI_00997 1.6e-33 secG U Preprotein translocase SecG subunit
COOAKMDI_00998 1.1e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COOAKMDI_00999 8.2e-162 S Sucrose-6F-phosphate phosphohydrolase
COOAKMDI_01000 6.3e-253 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
COOAKMDI_01001 1.4e-216 mepA_6 V MatE
COOAKMDI_01002 2.4e-216 brnQ U Component of the transport system for branched-chain amino acids
COOAKMDI_01003 5.7e-200 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COOAKMDI_01004 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
COOAKMDI_01005 6.7e-180 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COOAKMDI_01006 9.8e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COOAKMDI_01007 3.6e-156 G Fructosamine kinase
COOAKMDI_01008 9.4e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
COOAKMDI_01009 8.6e-127 S PAC2 family
COOAKMDI_01015 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COOAKMDI_01016 7.7e-111 hit 2.7.7.53 FG HIT domain
COOAKMDI_01017 2e-111 yebC K transcriptional regulatory protein
COOAKMDI_01018 3.1e-96 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
COOAKMDI_01019 2.3e-89 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COOAKMDI_01020 6.8e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COOAKMDI_01021 3.3e-37 yajC U Preprotein translocase subunit
COOAKMDI_01022 6.3e-89 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COOAKMDI_01023 1.9e-212 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
COOAKMDI_01024 1.5e-158 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
COOAKMDI_01025 1.3e-236
COOAKMDI_01026 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COOAKMDI_01027 2e-30
COOAKMDI_01028 1.6e-161 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COOAKMDI_01029 4.5e-143 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COOAKMDI_01030 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
COOAKMDI_01032 1.7e-295 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
COOAKMDI_01033 0.0 pafB K WYL domain
COOAKMDI_01034 5e-48
COOAKMDI_01035 0.0 helY L DEAD DEAH box helicase
COOAKMDI_01036 5.1e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
COOAKMDI_01037 2.7e-134 pgp 3.1.3.18 S HAD-hyrolase-like
COOAKMDI_01039 4.9e-45 ytrE_1 3.6.3.21 V ABC transporter
COOAKMDI_01040 1.2e-22 V efflux transmembrane transporter activity
COOAKMDI_01041 1.4e-71 T response regulator
COOAKMDI_01042 1.3e-66 2.7.13.3 T Histidine kinase
COOAKMDI_01044 9.2e-59
COOAKMDI_01045 4.9e-111 K helix_turn_helix, mercury resistance
COOAKMDI_01046 1.1e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
COOAKMDI_01047 1.4e-139 S Bacterial protein of unknown function (DUF881)
COOAKMDI_01048 1.2e-28 sbp S Protein of unknown function (DUF1290)
COOAKMDI_01049 1.6e-124 S Bacterial protein of unknown function (DUF881)
COOAKMDI_01050 6e-106 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COOAKMDI_01051 2.1e-157 hisG 2.4.2.17 F ATP phosphoribosyltransferase
COOAKMDI_01052 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
COOAKMDI_01053 3.6e-104 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
COOAKMDI_01054 1.2e-185 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COOAKMDI_01055 1.5e-158 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
COOAKMDI_01056 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
COOAKMDI_01057 3.2e-132 S SOS response associated peptidase (SRAP)
COOAKMDI_01058 4.1e-153 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
COOAKMDI_01059 2e-258 mmuP E amino acid
COOAKMDI_01060 2.4e-67 EGP Major facilitator Superfamily
COOAKMDI_01061 6e-188 V VanZ like family
COOAKMDI_01062 4e-14 cefD 5.1.1.17 E Aminotransferase, class V
COOAKMDI_01063 1.2e-17 cefD 5.1.1.17 E Aminotransferase, class V
COOAKMDI_01064 1.1e-34 S Uncharacterized protein conserved in bacteria (DUF2316)
COOAKMDI_01065 8e-99 S Acetyltransferase (GNAT) domain
COOAKMDI_01066 7e-26 L Transposase
COOAKMDI_01067 0.0 E Sodium:solute symporter family
COOAKMDI_01068 6.8e-43
COOAKMDI_01069 1.1e-27 L Transposase
COOAKMDI_01070 5.2e-121
COOAKMDI_01071 5.7e-51 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_01072 3.3e-126 L PFAM Integrase catalytic
COOAKMDI_01073 1.2e-178 tnp7109-2 L Transposase, Mutator family
COOAKMDI_01075 1.9e-15 V Abi-like protein
COOAKMDI_01076 5.9e-185 V Abi-like protein
COOAKMDI_01077 1.4e-150 L Phage integrase family
COOAKMDI_01078 4.5e-52 L Phage integrase family
COOAKMDI_01079 1.8e-144 fic D Fic/DOC family
COOAKMDI_01080 3.3e-26
COOAKMDI_01081 5.9e-212 L Integrase core domain
COOAKMDI_01082 8.9e-241 mloB K Putative DNA-binding domain
COOAKMDI_01083 1.8e-18 L Transposase
COOAKMDI_01084 6e-158 S AAA ATPase domain
COOAKMDI_01085 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
COOAKMDI_01086 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
COOAKMDI_01087 5.9e-269 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
COOAKMDI_01089 9.5e-169 hisN 3.1.3.25 G Inositol monophosphatase family
COOAKMDI_01090 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
COOAKMDI_01091 2.5e-286 arc O AAA ATPase forming ring-shaped complexes
COOAKMDI_01092 5e-125 apl 3.1.3.1 S SNARE associated Golgi protein
COOAKMDI_01093 1.6e-126 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
COOAKMDI_01094 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COOAKMDI_01095 1.3e-133 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COOAKMDI_01096 2.6e-180 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COOAKMDI_01097 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
COOAKMDI_01098 1.1e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COOAKMDI_01099 5.5e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COOAKMDI_01100 3.4e-218 vex3 V ABC transporter permease
COOAKMDI_01101 4.4e-209 vex1 V Efflux ABC transporter, permease protein
COOAKMDI_01102 7.1e-110 vex2 V ABC transporter, ATP-binding protein
COOAKMDI_01103 1.1e-97 ptpA 3.1.3.48 T low molecular weight
COOAKMDI_01104 2.8e-125 folA 1.5.1.3 H dihydrofolate reductase
COOAKMDI_01106 1.1e-172 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COOAKMDI_01107 6.9e-74 attW O OsmC-like protein
COOAKMDI_01108 2.3e-187 T Universal stress protein family
COOAKMDI_01109 1.9e-101 M NlpC/P60 family
COOAKMDI_01110 6.5e-79 M NlpC/P60 family
COOAKMDI_01111 1.8e-165 usp 3.5.1.28 CBM50 S CHAP domain
COOAKMDI_01112 3.4e-211 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COOAKMDI_01113 9.5e-37
COOAKMDI_01114 4.3e-193 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
COOAKMDI_01115 4.5e-115 phoU P Plays a role in the regulation of phosphate uptake
COOAKMDI_01116 1.4e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COOAKMDI_01117 1.5e-25 T Histidine kinase
COOAKMDI_01118 2.6e-41 K helix_turn_helix, Lux Regulon
COOAKMDI_01119 8.1e-16
COOAKMDI_01120 8.7e-140 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
COOAKMDI_01121 8.4e-25 2.7.13.3 T Histidine kinase
COOAKMDI_01122 5.4e-39 K helix_turn_helix, Lux Regulon
COOAKMDI_01126 2.8e-310 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COOAKMDI_01128 3.4e-206 araJ EGP Major facilitator Superfamily
COOAKMDI_01129 0.0 S Domain of unknown function (DUF4037)
COOAKMDI_01130 2.6e-112 S Protein of unknown function (DUF4125)
COOAKMDI_01131 1.5e-281 S alpha beta
COOAKMDI_01132 2.9e-56
COOAKMDI_01133 2e-165 pspC KT PspC domain
COOAKMDI_01134 1.2e-225 tcsS3 KT PspC domain
COOAKMDI_01135 5.9e-110 degU K helix_turn_helix, Lux Regulon
COOAKMDI_01136 1.3e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COOAKMDI_01137 2e-304 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COOAKMDI_01138 8.7e-193 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
COOAKMDI_01139 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
COOAKMDI_01141 3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COOAKMDI_01142 1.7e-202 I Diacylglycerol kinase catalytic domain
COOAKMDI_01143 8.9e-159 arbG K CAT RNA binding domain
COOAKMDI_01144 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
COOAKMDI_01145 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
COOAKMDI_01146 3.2e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
COOAKMDI_01147 5e-67 K Transcriptional regulator
COOAKMDI_01148 1.7e-277 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COOAKMDI_01150 8.7e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COOAKMDI_01151 1.5e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COOAKMDI_01153 3.9e-92
COOAKMDI_01154 2.8e-277 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COOAKMDI_01155 1.5e-216 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
COOAKMDI_01156 1.7e-210 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COOAKMDI_01157 7.1e-73 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COOAKMDI_01158 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COOAKMDI_01159 4.3e-184 nusA K Participates in both transcription termination and antitermination
COOAKMDI_01160 6.8e-125
COOAKMDI_01161 6.2e-244 G Bacterial extracellular solute-binding protein
COOAKMDI_01162 8.2e-174 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_01163 1.4e-159 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_01164 6.7e-83 L Transposase and inactivated derivatives IS30 family
COOAKMDI_01166 5.9e-23 D COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
COOAKMDI_01167 3.9e-33 S Bacterial protein of unknown function (DUF961)
COOAKMDI_01168 1.5e-42 yxaM EGP Major Facilitator Superfamily
COOAKMDI_01170 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_01171 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COOAKMDI_01172 4.2e-83 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
COOAKMDI_01173 1.9e-46 S Domain of unknown function (DUF4193)
COOAKMDI_01174 2e-168 S Protein of unknown function (DUF3071)
COOAKMDI_01175 2e-233 S Type I phosphodiesterase / nucleotide pyrophosphatase
COOAKMDI_01176 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
COOAKMDI_01177 3.1e-123 KT RESPONSE REGULATOR receiver
COOAKMDI_01178 0.0 lhr L DEAD DEAH box helicase
COOAKMDI_01179 2.9e-78 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COOAKMDI_01180 1.4e-199 G Major Facilitator Superfamily
COOAKMDI_01181 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
COOAKMDI_01182 5.8e-189 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COOAKMDI_01183 7.6e-123
COOAKMDI_01184 5.3e-190 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
COOAKMDI_01185 0.0 pknL 2.7.11.1 KLT PASTA
COOAKMDI_01186 1.1e-127 plsC2 2.3.1.51 I Phosphate acyltransferases
COOAKMDI_01187 2.6e-75
COOAKMDI_01188 7.4e-173 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COOAKMDI_01189 3.1e-65 E GDSL-like Lipase/Acylhydrolase family
COOAKMDI_01190 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COOAKMDI_01191 2.4e-116 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COOAKMDI_01192 8.9e-99 recX S Modulates RecA activity
COOAKMDI_01193 6.4e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COOAKMDI_01194 5.3e-39 S Protein of unknown function (DUF3046)
COOAKMDI_01195 1.1e-81 K Helix-turn-helix XRE-family like proteins
COOAKMDI_01196 1.8e-90 cinA 3.5.1.42 S Belongs to the CinA family
COOAKMDI_01197 1.7e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COOAKMDI_01198 0.0 ftsK D FtsK SpoIIIE family protein
COOAKMDI_01199 5.9e-137 fic D Fic/DOC family
COOAKMDI_01200 1.5e-183 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COOAKMDI_01201 4.5e-277 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
COOAKMDI_01202 7.2e-91 tnp3512a L Transposase
COOAKMDI_01203 6.4e-77 tnp3512a L Transposase
COOAKMDI_01204 4.9e-114 L Transposase and inactivated derivatives IS30 family
COOAKMDI_01205 2e-115 L Transposase and inactivated derivatives IS30 family
COOAKMDI_01206 6.4e-175 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_01207 1.2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
COOAKMDI_01208 2.5e-191 galM 5.1.3.3 G Aldose 1-epimerase
COOAKMDI_01209 1.1e-186 galM 5.1.3.3 G Aldose 1-epimerase
COOAKMDI_01210 1.6e-54
COOAKMDI_01211 1.4e-127 sigH K Belongs to the sigma-70 factor family. ECF subfamily
COOAKMDI_01212 2.9e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COOAKMDI_01213 4.1e-189 V Acetyltransferase (GNAT) domain
COOAKMDI_01214 0.0 smc D Required for chromosome condensation and partitioning
COOAKMDI_01215 1.2e-281 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
COOAKMDI_01216 1.5e-159 K Psort location Cytoplasmic, score
COOAKMDI_01217 2.8e-304 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
COOAKMDI_01218 7.9e-75 3.6.1.55 F NUDIX domain
COOAKMDI_01219 3.7e-188 3.2.1.51 GH29 G Alpha-L-fucosidase
COOAKMDI_01222 2.1e-126 G Binding-protein-dependent transport systems inner membrane component
COOAKMDI_01223 4.4e-105 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_01224 2.4e-192 G Bacterial extracellular solute-binding protein
COOAKMDI_01225 2.2e-235 nagA 3.5.1.25 G Amidohydrolase family
COOAKMDI_01226 3.1e-150 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COOAKMDI_01227 1.6e-202 GK ROK family
COOAKMDI_01228 1.4e-162 2.7.1.2 GK ROK family
COOAKMDI_01229 3.6e-219 GK ROK family
COOAKMDI_01230 4.7e-168 2.7.1.4 G pfkB family carbohydrate kinase
COOAKMDI_01231 3.4e-70 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COOAKMDI_01232 1.1e-10 fucP G Major Facilitator Superfamily
COOAKMDI_01233 3.3e-17 fucP G Major Facilitator Superfamily
COOAKMDI_01234 8.7e-256 S Metal-independent alpha-mannosidase (GH125)
COOAKMDI_01235 3.1e-247 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
COOAKMDI_01236 6.4e-183 K helix_turn _helix lactose operon repressor
COOAKMDI_01237 0.0 G Glycosyl hydrolase family 85
COOAKMDI_01238 0.0 bglX-2 3.2.1.21 GH3 G Glycosyl hydrolase family 3 C-terminal domain
COOAKMDI_01239 5.2e-253 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
COOAKMDI_01240 1.9e-155 lacG G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01241 3.1e-165 G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01242 5.1e-248 srrA1 G Bacterial extracellular solute-binding protein
COOAKMDI_01243 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
COOAKMDI_01244 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
COOAKMDI_01245 5.8e-88 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COOAKMDI_01246 4.1e-15
COOAKMDI_01247 2.8e-183 ftsQ 6.3.2.4 D Cell division protein FtsQ
COOAKMDI_01248 3.6e-285 murC 6.3.2.8 M Belongs to the MurCDEF family
COOAKMDI_01249 5.7e-222 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COOAKMDI_01250 8.5e-221 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
COOAKMDI_01251 1.4e-270 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COOAKMDI_01252 2.5e-203 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COOAKMDI_01253 7e-246 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COOAKMDI_01254 7.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COOAKMDI_01255 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
COOAKMDI_01256 3.2e-72 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
COOAKMDI_01257 1.2e-194 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COOAKMDI_01258 1.9e-92 mraZ K Belongs to the MraZ family
COOAKMDI_01259 0.0 L DNA helicase
COOAKMDI_01260 2.7e-227 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
COOAKMDI_01261 5.3e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COOAKMDI_01262 5.9e-36 M Lysin motif
COOAKMDI_01263 1e-128 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COOAKMDI_01264 6.7e-157 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COOAKMDI_01265 1.5e-175 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
COOAKMDI_01266 4.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COOAKMDI_01267 4.4e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
COOAKMDI_01268 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
COOAKMDI_01269 9.2e-173 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
COOAKMDI_01270 1.5e-308 P Belongs to the ABC transporter superfamily
COOAKMDI_01271 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
COOAKMDI_01272 5.8e-175 EP Binding-protein-dependent transport system inner membrane component
COOAKMDI_01273 1.6e-142 appC EP Binding-protein-dependent transport system inner membrane component
COOAKMDI_01274 1.1e-188 EGP Major facilitator Superfamily
COOAKMDI_01275 5.2e-264 glnA2 6.3.1.2 E glutamine synthetase
COOAKMDI_01276 7.7e-20 S Uncharacterized protein conserved in bacteria (DUF2252)
COOAKMDI_01277 6.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
COOAKMDI_01278 1e-119 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COOAKMDI_01279 2.3e-97
COOAKMDI_01280 2.3e-110 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
COOAKMDI_01281 1.2e-219 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COOAKMDI_01282 1.6e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
COOAKMDI_01283 4.1e-278 2.7.1.17 GH19 G FGGY family of carbohydrate kinases, N-terminal domain
COOAKMDI_01284 2.9e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
COOAKMDI_01285 2.4e-127 L Transposase and inactivated derivatives IS30 family
COOAKMDI_01286 1.2e-178 tnp7109-2 L Transposase, Mutator family
COOAKMDI_01287 5.9e-212 L Integrase core domain
COOAKMDI_01290 8.6e-11 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
COOAKMDI_01291 2.5e-201 L Transposase, Mutator family
COOAKMDI_01292 1.1e-33 D Filamentation induced by cAMP protein fic
COOAKMDI_01293 5.1e-240 EGP Major facilitator Superfamily
COOAKMDI_01294 2.5e-47 thiF 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
COOAKMDI_01295 5.4e-33 L PFAM Integrase catalytic
COOAKMDI_01296 7.7e-202 L Phage integrase, N-terminal SAM-like domain
COOAKMDI_01297 2e-193 L Phage integrase family
COOAKMDI_01298 2.1e-227 xerC_1 L Belongs to the 'phage' integrase family
COOAKMDI_01299 2.6e-19 L PFAM Integrase catalytic
COOAKMDI_01300 2.7e-264 EGP Major Facilitator Superfamily
COOAKMDI_01301 0.0 1.3.3.6, 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
COOAKMDI_01302 0.0 H Beta-ketoacyl synthase, C-terminal domain
COOAKMDI_01303 2.5e-115 K WHG domain
COOAKMDI_01304 2.9e-111 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
COOAKMDI_01305 2.8e-60 L PFAM Integrase catalytic
COOAKMDI_01306 3e-14 L PFAM Integrase catalytic
COOAKMDI_01307 3.7e-66 L PFAM Integrase catalytic
COOAKMDI_01309 3.2e-158 S Fic/DOC family
COOAKMDI_01310 1.1e-245 S HipA-like C-terminal domain
COOAKMDI_01312 9.8e-73
COOAKMDI_01313 4.6e-94 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COOAKMDI_01314 5.9e-212 L Integrase core domain
COOAKMDI_01315 2.6e-211 G Periplasmic binding protein domain
COOAKMDI_01316 3e-295 araG 3.6.3.17 G ATPases associated with a variety of cellular activities
COOAKMDI_01317 2.2e-197 gguB U Branched-chain amino acid transport system / permease component
COOAKMDI_01318 8.1e-41
COOAKMDI_01319 2.9e-90 K Winged helix DNA-binding domain
COOAKMDI_01320 6.8e-67 EGP Major facilitator superfamily
COOAKMDI_01321 2.8e-70 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
COOAKMDI_01322 1.3e-153
COOAKMDI_01323 5.9e-22 EGP Major facilitator Superfamily
COOAKMDI_01324 5.5e-68 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
COOAKMDI_01325 3e-226 xylR GK ROK family
COOAKMDI_01327 1.3e-36 rpmE J Binds the 23S rRNA
COOAKMDI_01328 4.5e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COOAKMDI_01329 1e-143 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COOAKMDI_01330 3.6e-200 livK E Receptor family ligand binding region
COOAKMDI_01331 1.2e-105 U Belongs to the binding-protein-dependent transport system permease family
COOAKMDI_01332 1.4e-171 livM U Belongs to the binding-protein-dependent transport system permease family
COOAKMDI_01333 3.1e-153 E Branched-chain amino acid ATP-binding cassette transporter
COOAKMDI_01334 1.5e-121 livF E ATPases associated with a variety of cellular activities
COOAKMDI_01335 1.8e-119 ywlC 2.7.7.87 J Belongs to the SUA5 family
COOAKMDI_01336 3.8e-203 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
COOAKMDI_01337 4.9e-290 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
COOAKMDI_01338 2.7e-117 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
COOAKMDI_01339 2.6e-269 recD2 3.6.4.12 L PIF1-like helicase
COOAKMDI_01340 2.7e-35 S AMMECR1
COOAKMDI_01341 4.9e-27 GT87 NU Tfp pilus assembly protein FimV
COOAKMDI_01342 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COOAKMDI_01343 7.9e-52 L Single-strand binding protein family
COOAKMDI_01344 0.0 pepO 3.4.24.71 O Peptidase family M13
COOAKMDI_01345 3.3e-98 S Short repeat of unknown function (DUF308)
COOAKMDI_01346 9.2e-152 map 3.4.11.18 E Methionine aminopeptidase
COOAKMDI_01347 5.1e-248 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
COOAKMDI_01348 1.4e-144 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
COOAKMDI_01349 2.2e-212 K WYL domain
COOAKMDI_01350 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
COOAKMDI_01351 2.8e-79 S PFAM Uncharacterised protein family UPF0150
COOAKMDI_01352 1.3e-35 XK27_03610 K Acetyltransferase (GNAT) domain
COOAKMDI_01353 5.4e-84 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
COOAKMDI_01354 9.4e-200 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
COOAKMDI_01355 2.7e-224 aspB E Aminotransferase class-V
COOAKMDI_01356 6.4e-08 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
COOAKMDI_01357 2.7e-10 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
COOAKMDI_01358 1.4e-193 S Endonuclease/Exonuclease/phosphatase family
COOAKMDI_01360 5.9e-76 F Nucleoside 2-deoxyribosyltransferase
COOAKMDI_01361 0.0 fadD 6.2.1.3 I AMP-binding enzyme
COOAKMDI_01362 5.5e-92 ywrO 1.6.5.2 S Flavodoxin-like fold
COOAKMDI_01363 3.8e-234 S peptidyl-serine autophosphorylation
COOAKMDI_01364 1.2e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COOAKMDI_01365 8.5e-254 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COOAKMDI_01366 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
COOAKMDI_01367 8e-142 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COOAKMDI_01368 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
COOAKMDI_01369 6.5e-256 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
COOAKMDI_01370 1.1e-63 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
COOAKMDI_01371 7.7e-70 S Nucleotidyltransferase substrate binding protein like
COOAKMDI_01372 1.3e-229 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
COOAKMDI_01373 4.7e-84 K Bacterial regulatory proteins, tetR family
COOAKMDI_01374 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
COOAKMDI_01375 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
COOAKMDI_01376 1.1e-161
COOAKMDI_01377 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
COOAKMDI_01378 4.7e-279 pelF GT4 M Domain of unknown function (DUF3492)
COOAKMDI_01379 1.8e-284 pelG S Putative exopolysaccharide Exporter (EPS-E)
COOAKMDI_01380 5e-311 cotH M CotH kinase protein
COOAKMDI_01381 3.8e-156 P VTC domain
COOAKMDI_01382 1.1e-110 S Domain of unknown function (DUF4956)
COOAKMDI_01383 0.0 yliE T Putative diguanylate phosphodiesterase
COOAKMDI_01384 0.0 V ABC transporter, ATP-binding protein
COOAKMDI_01385 0.0 V ABC transporter transmembrane region
COOAKMDI_01386 8.3e-47 rbsR K helix_turn _helix lactose operon repressor
COOAKMDI_01387 2.5e-164 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
COOAKMDI_01388 3.2e-187 EGP Major facilitator Superfamily
COOAKMDI_01389 4.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COOAKMDI_01390 1.3e-174 lacR K Transcriptional regulator, LacI family
COOAKMDI_01391 4.5e-108 K FCD
COOAKMDI_01392 3.1e-143 L Domain of unknown function (DUF4862)
COOAKMDI_01393 1.3e-120 2.7.1.2 GK ROK family
COOAKMDI_01394 7.8e-115 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
COOAKMDI_01395 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
COOAKMDI_01396 8e-272 E Bacterial extracellular solute-binding proteins, family 5 Middle
COOAKMDI_01397 7.2e-167 oppB6 EP Binding-protein-dependent transport system inner membrane component
COOAKMDI_01398 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
COOAKMDI_01399 8.5e-143 oppF E ATPases associated with a variety of cellular activities
COOAKMDI_01400 3.9e-160 nanL 4.3.3.7 EM Dihydrodipicolinate synthetase family
COOAKMDI_01401 1e-242 malY 4.4.1.8 E Aminotransferase, class I II
COOAKMDI_01402 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COOAKMDI_01403 0.0 L DEAD-like helicases superfamily
COOAKMDI_01404 3.9e-103 cas5d S CRISPR-associated protein (Cas_Cas5)
COOAKMDI_01405 4.6e-244 csd1 S CRISPR-associated protein (Cas_Csd1)
COOAKMDI_01406 2e-145 cas7c L CRISPR-associated protein Cas7
COOAKMDI_01407 2.2e-112 cas4 3.1.12.1 L Domain of unknown function DUF83
COOAKMDI_01408 8.9e-179 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COOAKMDI_01409 9.2e-41 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COOAKMDI_01410 7.4e-109 S Psort location Cytoplasmic, score 8.87
COOAKMDI_01412 3.3e-13
COOAKMDI_01413 9e-11
COOAKMDI_01414 2.7e-54
COOAKMDI_01416 1.1e-34
COOAKMDI_01417 5.9e-212 L Integrase core domain
COOAKMDI_01418 3e-81
COOAKMDI_01419 2e-241 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
COOAKMDI_01420 4.2e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
COOAKMDI_01421 1.1e-158 S Sucrose-6F-phosphate phosphohydrolase
COOAKMDI_01423 2e-81 G transmembrane transporter activity
COOAKMDI_01425 2.2e-205 EGP Major facilitator Superfamily
COOAKMDI_01426 2.9e-73 L Transposase, Mutator family
COOAKMDI_01427 3.6e-94 bcp 1.11.1.15 O Redoxin
COOAKMDI_01428 2.5e-139
COOAKMDI_01429 2.6e-64 CP_1020 S zinc finger
COOAKMDI_01430 4.2e-12 2.5.1.19 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COOAKMDI_01431 1.8e-31 mazG S MazG-like family
COOAKMDI_01432 1.2e-206 L Uncharacterized conserved protein (DUF2075)
COOAKMDI_01433 1.3e-30 S zinc finger
COOAKMDI_01434 2.4e-31 rarD S EamA-like transporter family
COOAKMDI_01435 2.3e-124 S Plasmid pRiA4b ORF-3-like protein
COOAKMDI_01436 4.8e-178 CP_1020 S zinc ion binding
COOAKMDI_01438 6.8e-170 I alpha/beta hydrolase fold
COOAKMDI_01439 7.6e-12 ydhF S Aldo/keto reductase family
COOAKMDI_01440 2.5e-23 ydhF S Aldo/keto reductase family
COOAKMDI_01441 9.1e-73 S phosphoesterase or phosphohydrolase
COOAKMDI_01443 4.2e-94 S Phospholipase/Carboxylesterase
COOAKMDI_01444 1.3e-193 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
COOAKMDI_01445 1.2e-97 sixA 3.6.1.55 T Phosphoglycerate mutase family
COOAKMDI_01446 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COOAKMDI_01447 1.1e-155 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
COOAKMDI_01448 1.8e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COOAKMDI_01449 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
COOAKMDI_01450 9.2e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COOAKMDI_01451 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
COOAKMDI_01452 1e-284 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COOAKMDI_01453 9.4e-175 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
COOAKMDI_01454 2e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
COOAKMDI_01455 1.8e-181 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COOAKMDI_01456 1.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COOAKMDI_01457 9e-29
COOAKMDI_01458 3.5e-213 MA20_36090 S Psort location Cytoplasmic, score 8.87
COOAKMDI_01459 8e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
COOAKMDI_01460 6.6e-11 V ABC transporter transmembrane region
COOAKMDI_01461 4.8e-119 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COOAKMDI_01462 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COOAKMDI_01463 1.5e-230 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
COOAKMDI_01464 1.4e-136 KL DEAD-like helicases superfamily
COOAKMDI_01465 6.1e-45 yeaO K Protein of unknown function, DUF488
COOAKMDI_01466 1.2e-50 S Virulence protein RhuM family
COOAKMDI_01467 1.1e-07 V ATPases associated with a variety of cellular activities
COOAKMDI_01468 2.3e-16 yijF S Domain of unknown function (DUF1287)
COOAKMDI_01469 1e-156 3.6.4.12
COOAKMDI_01470 3.8e-75
COOAKMDI_01471 4.8e-63 yeaO K Protein of unknown function, DUF488
COOAKMDI_01473 2.1e-264 mmuP E amino acid
COOAKMDI_01474 9e-46 2.6.1.76 EGP Major Facilitator Superfamily
COOAKMDI_01476 7.6e-91 yidC U Membrane protein insertase, YidC Oxa1 family
COOAKMDI_01477 2.9e-116 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
COOAKMDI_01478 4.6e-32 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
COOAKMDI_01479 8.4e-66 hipA 2.7.11.1 S kinase activity
COOAKMDI_01480 1.9e-37 K sequence-specific DNA binding
COOAKMDI_01481 1.5e-220 merA 1.16.1.1 C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
COOAKMDI_01482 4e-256 tnpA1 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COOAKMDI_01483 1.2e-104
COOAKMDI_01484 4.1e-32 K Transcriptional regulator
COOAKMDI_01485 8.9e-61 2.7.13.3 T Histidine kinase
COOAKMDI_01486 4.6e-48 S Bacterial toxin of type II toxin-antitoxin system, YafQ
COOAKMDI_01487 3.2e-40 relB L RelB antitoxin
COOAKMDI_01488 1e-175 V MacB-like periplasmic core domain
COOAKMDI_01489 1.4e-124 lolD Q ATPases associated with a variety of cellular activities
COOAKMDI_01490 3.6e-144 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COOAKMDI_01491 3e-95
COOAKMDI_01492 2e-126 K helix_turn_helix, Lux Regulon
COOAKMDI_01493 4.2e-193 2.7.13.3 T Histidine kinase
COOAKMDI_01494 2e-35 2.7.13.3 T Histidine kinase
COOAKMDI_01497 6.7e-102 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_01498 5.4e-153 L PFAM Integrase catalytic
COOAKMDI_01499 1.2e-178 tnp7109-2 L Transposase, Mutator family
COOAKMDI_01500 5.9e-212 L Integrase core domain
COOAKMDI_01501 3.3e-214 GK ROK family
COOAKMDI_01502 5.8e-155 xylG 3.6.3.17 G ATPases associated with a variety of cellular activities
COOAKMDI_01503 3.4e-177 glkA 2.7.1.2 G ROK family
COOAKMDI_01504 3e-228 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_01505 1.2e-10 6.3.1.2 E glutamine synthetase
COOAKMDI_01506 2.6e-16 S Amidohydrolase
COOAKMDI_01507 2.1e-154 S Patatin-like phospholipase
COOAKMDI_01508 2.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COOAKMDI_01509 3.6e-168 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
COOAKMDI_01510 2.1e-126 S Vitamin K epoxide reductase
COOAKMDI_01511 2.5e-169 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
COOAKMDI_01512 1.2e-32 S Protein of unknown function (DUF3107)
COOAKMDI_01513 7.8e-286 mphA S Aminoglycoside phosphotransferase
COOAKMDI_01514 2.6e-286 uvrD2 3.6.4.12 L DNA helicase
COOAKMDI_01515 0.0 S Zincin-like metallopeptidase
COOAKMDI_01516 2.3e-159 lon T Belongs to the peptidase S16 family
COOAKMDI_01517 2e-44 S Protein of unknown function (DUF3052)
COOAKMDI_01519 5e-227 2.7.11.1 NU Tfp pilus assembly protein FimV
COOAKMDI_01520 5.2e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COOAKMDI_01521 2.8e-232 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
COOAKMDI_01522 1.9e-282 I acetylesterase activity
COOAKMDI_01523 2.7e-113 recO L Involved in DNA repair and RecF pathway recombination
COOAKMDI_01524 1.3e-153 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COOAKMDI_01525 6.5e-197 iunH1 3.2.2.1 F nucleoside hydrolase
COOAKMDI_01526 4.1e-203 P NMT1/THI5 like
COOAKMDI_01527 5.8e-138 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_01528 7.3e-302 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
COOAKMDI_01529 6.2e-241 lacY P LacY proton/sugar symporter
COOAKMDI_01530 2.3e-195 K helix_turn _helix lactose operon repressor
COOAKMDI_01531 2.2e-244 O SERine Proteinase INhibitors
COOAKMDI_01532 2.1e-18
COOAKMDI_01533 1.2e-61 S Thiamine-binding protein
COOAKMDI_01534 8.7e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COOAKMDI_01535 1e-198 O AAA domain (Cdc48 subfamily)
COOAKMDI_01536 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
COOAKMDI_01537 1.6e-163 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COOAKMDI_01538 2.6e-296 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
COOAKMDI_01539 3.2e-239 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COOAKMDI_01540 3e-194 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COOAKMDI_01541 7.5e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COOAKMDI_01542 3.9e-42 yggT S YGGT family
COOAKMDI_01543 4.1e-38 tccB2 V DivIVA protein
COOAKMDI_01544 3.1e-90 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COOAKMDI_01545 1.3e-179 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
COOAKMDI_01546 4.3e-54 V ATPases associated with a variety of cellular activities
COOAKMDI_01547 1.7e-102
COOAKMDI_01548 6e-128 S Virulence factor BrkB
COOAKMDI_01549 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
COOAKMDI_01550 6.8e-75 yneG S Domain of unknown function (DUF4186)
COOAKMDI_01551 0.0 4.2.1.53 S MCRA family
COOAKMDI_01552 1.4e-159 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_01553 8.2e-174 P Binding-protein-dependent transport system inner membrane component
COOAKMDI_01554 4.4e-165 G Bacterial extracellular solute-binding protein
COOAKMDI_01555 3.6e-63 4.2.1.68 M Enolase C-terminal domain-like
COOAKMDI_01556 4.3e-22 4.2.1.68 M Enolase C-terminal domain-like
COOAKMDI_01557 4.7e-102 uhpT EGP Major facilitator Superfamily
COOAKMDI_01558 8.3e-205 G Hypothetical glycosyl hydrolase 6
COOAKMDI_01559 1.1e-08 S Domain of unknown function (DUF3841)
COOAKMDI_01560 5.7e-29 V Type II restriction enzyme, methylase subunits
COOAKMDI_01561 1.1e-58 L Transposase DDE domain
COOAKMDI_01562 7.3e-104 rsmD 2.1.1.171 L Conserved hypothetical protein 95
COOAKMDI_01563 2.1e-154 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COOAKMDI_01564 1.3e-309 yegQ O Peptidase family U32 C-terminal domain
COOAKMDI_01565 3.7e-182 yfiH Q Multi-copper polyphenol oxidoreductase laccase
COOAKMDI_01566 3e-159 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
COOAKMDI_01567 3.8e-122 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COOAKMDI_01568 4.5e-57 D nuclear chromosome segregation
COOAKMDI_01569 1.7e-262 pepC 3.4.22.40 E Peptidase C1-like family
COOAKMDI_01570 5e-215 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
COOAKMDI_01571 1.8e-234 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
COOAKMDI_01572 1.1e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COOAKMDI_01573 1.9e-20 EGP Sugar (and other) transporter
COOAKMDI_01574 3.8e-199 EGP Sugar (and other) transporter
COOAKMDI_01575 6.3e-204 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
COOAKMDI_01576 6.7e-139 KT Transcriptional regulatory protein, C terminal
COOAKMDI_01577 4e-180 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
COOAKMDI_01578 3.5e-153 pstC P probably responsible for the translocation of the substrate across the membrane
COOAKMDI_01579 1.1e-168 pstA P Phosphate transport system permease
COOAKMDI_01580 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COOAKMDI_01581 2.5e-90 lemA S LemA family
COOAKMDI_01582 0.0 S Predicted membrane protein (DUF2207)
COOAKMDI_01583 8.8e-41 S Predicted membrane protein (DUF2207)
COOAKMDI_01584 2e-173 S Predicted membrane protein (DUF2207)
COOAKMDI_01585 1.1e-17
COOAKMDI_01586 1.9e-166 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
COOAKMDI_01587 5.7e-197 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
COOAKMDI_01588 3.3e-122 K helix_turn _helix lactose operon repressor
COOAKMDI_01589 1.8e-141 G Bacterial extracellular solute-binding protein
COOAKMDI_01590 1.6e-118 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_01591 7.6e-112 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_01592 3.1e-226
COOAKMDI_01593 2.7e-120 2.7.11.1 S Pfam:HipA_N
COOAKMDI_01594 2.8e-45 K Helix-turn-helix XRE-family like proteins
COOAKMDI_01595 1.1e-110 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COOAKMDI_01596 6.1e-35 CP_0960 S Belongs to the UPF0109 family
COOAKMDI_01597 1.1e-59 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COOAKMDI_01598 5.5e-144 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
COOAKMDI_01599 2.9e-273 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
COOAKMDI_01600 5e-212 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COOAKMDI_01601 2.2e-111 ribE 2.5.1.9 H Lumazine binding domain
COOAKMDI_01602 6e-235 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COOAKMDI_01603 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COOAKMDI_01604 6e-165 S Endonuclease/Exonuclease/phosphatase family
COOAKMDI_01605 4.4e-263 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COOAKMDI_01606 6.7e-162 P Cation efflux family
COOAKMDI_01607 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
COOAKMDI_01608 5.3e-137 guaA1 6.3.5.2 F Peptidase C26
COOAKMDI_01609 0.0 yjjK S ABC transporter
COOAKMDI_01610 8.6e-44 stbC S Plasmid stability protein
COOAKMDI_01611 1.7e-91 ilvN 2.2.1.6 E ACT domain
COOAKMDI_01612 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
COOAKMDI_01613 1.2e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COOAKMDI_01614 7.6e-31 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COOAKMDI_01615 1.4e-118 yceD S Uncharacterized ACR, COG1399
COOAKMDI_01616 2e-118
COOAKMDI_01617 4.6e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COOAKMDI_01618 2e-51 S Protein of unknown function (DUF3039)
COOAKMDI_01619 1.7e-190 yghZ C Aldo/keto reductase family
COOAKMDI_01620 5.3e-69 soxR K MerR, DNA binding
COOAKMDI_01621 1.6e-114
COOAKMDI_01622 1.4e-248 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COOAKMDI_01623 1.2e-160
COOAKMDI_01624 4.1e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
COOAKMDI_01625 1e-131 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COOAKMDI_01627 1.2e-214 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
COOAKMDI_01628 5.7e-255 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
COOAKMDI_01629 5.2e-229 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
COOAKMDI_01630 6.2e-169 S Auxin Efflux Carrier
COOAKMDI_01633 0.0 pgi 5.3.1.9 G Belongs to the GPI family
COOAKMDI_01634 9.5e-256 abcT3 P ATPases associated with a variety of cellular activities
COOAKMDI_01635 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
COOAKMDI_01636 1.1e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COOAKMDI_01637 1.5e-136 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COOAKMDI_01638 1.7e-148 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COOAKMDI_01639 8.9e-209 K helix_turn _helix lactose operon repressor
COOAKMDI_01640 4.7e-94 uhpT EGP Major facilitator Superfamily
COOAKMDI_01641 1.5e-138 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
COOAKMDI_01642 0.0 fadD 6.2.1.3 I AMP-binding enzyme
COOAKMDI_01643 9.2e-22 araE EGP Major facilitator Superfamily
COOAKMDI_01644 1.8e-95 cydD V ABC transporter transmembrane region
COOAKMDI_01645 1.7e-75 cydD V ABC transporter transmembrane region
COOAKMDI_01646 1.1e-247 araE EGP Major facilitator Superfamily
COOAKMDI_01647 5.3e-101 2.7.13.3 T Histidine kinase
COOAKMDI_01648 4.3e-41 K helix_turn_helix, Lux Regulon
COOAKMDI_01649 2.2e-19 S Bacteriocin (Lactococcin_972)
COOAKMDI_01650 1.1e-241 XK27_10205
COOAKMDI_01651 4.7e-101 V ABC transporter
COOAKMDI_01652 1.1e-26
COOAKMDI_01653 2e-24 L Transposase
COOAKMDI_01654 2.1e-19 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
COOAKMDI_01655 6.9e-169 K helix_turn _helix lactose operon repressor
COOAKMDI_01656 4.1e-15 tnp3512a L Transposase
COOAKMDI_01658 1.2e-51 tnp7109-2 L Transposase, Mutator family
COOAKMDI_01659 7.9e-147 V ABC transporter, ATP-binding protein
COOAKMDI_01660 1.9e-137 lanM V Lanthionine synthetase C family protein
COOAKMDI_01661 2.4e-115 L Transposase and inactivated derivatives IS30 family
COOAKMDI_01662 7.9e-217 L Transposase, Mutator family
COOAKMDI_01663 6.2e-165 dprA LU DNA recombination-mediator protein A
COOAKMDI_01664 2.5e-146 S competence protein
COOAKMDI_01665 2.3e-101 S PIN domain
COOAKMDI_01666 1.5e-141
COOAKMDI_01667 2.8e-08
COOAKMDI_01668 3.3e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COOAKMDI_01669 6.5e-268 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COOAKMDI_01670 6.9e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COOAKMDI_01671 3.9e-167 M Domain of unknown function (DUF1972)
COOAKMDI_01672 4.9e-201 M Glycosyl transferase 4-like domain
COOAKMDI_01673 3.9e-161 lspL 5.1.3.6 GM Polysaccharide biosynthesis protein
COOAKMDI_01674 8.4e-216 1.1.1.22 M UDP binding domain
COOAKMDI_01675 8.9e-65 M Glycosyl transferases group 1
COOAKMDI_01676 4.3e-107 1.1.1.339 GM GDP-mannose 4,6 dehydratase
COOAKMDI_01677 5.2e-59 2.3.1.30 E Hexapeptide repeat of succinyl-transferase
COOAKMDI_01678 1.6e-159 MA20_43635 M Capsular polysaccharide synthesis protein
COOAKMDI_01679 3.1e-06 S Psort location CytoplasmicMembrane, score 10.00
COOAKMDI_01680 4e-29 GT8 S Protein conserved in bacteria
COOAKMDI_01681 1e-113 cps4J S Polysaccharide biosynthesis protein
COOAKMDI_01682 6.1e-18 capG S Bacterial transferase hexapeptide (six repeats)
COOAKMDI_01683 3.3e-113 wbiB 5.1.3.25 GM 3-beta hydroxysteroid dehydrogenase/isomerase family
COOAKMDI_01684 1.2e-32 GM Bacterial transferase hexapeptide (six repeats)
COOAKMDI_01685 1.6e-78 L Transposase
COOAKMDI_01686 5.4e-115 S Psort location CytoplasmicMembrane, score 9.99
COOAKMDI_01687 1.4e-107 3.1.3.48 T Low molecular weight phosphatase family
COOAKMDI_01688 4.8e-235 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
COOAKMDI_01689 7.9e-217 L Transposase, Mutator family
COOAKMDI_01690 3.4e-27 L Transposase
COOAKMDI_01692 1.5e-237 wcoI DM Psort location CytoplasmicMembrane, score
COOAKMDI_01693 5e-124
COOAKMDI_01694 2.6e-133 2.7.11.1 S HipA-like C-terminal domain
COOAKMDI_01695 6.6e-19 hipB K Helix-turn-helix XRE-family like proteins
COOAKMDI_01696 1.6e-169 S G5
COOAKMDI_01697 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
COOAKMDI_01698 7.3e-126 F Domain of unknown function (DUF4916)
COOAKMDI_01699 1.5e-160 mhpC I Alpha/beta hydrolase family
COOAKMDI_01700 1.4e-226 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
COOAKMDI_01701 1.2e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
COOAKMDI_01702 4.3e-250 S Uncharacterized conserved protein (DUF2183)
COOAKMDI_01703 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
COOAKMDI_01704 4.1e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
COOAKMDI_01705 4e-198 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
COOAKMDI_01706 4.4e-133 glxR K helix_turn_helix, cAMP Regulatory protein
COOAKMDI_01707 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
COOAKMDI_01708 7.6e-234 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
COOAKMDI_01709 1.1e-225 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
COOAKMDI_01710 1.2e-121 glpR K DeoR C terminal sensor domain
COOAKMDI_01711 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
COOAKMDI_01712 1.4e-231 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
COOAKMDI_01713 1.9e-43 gcvR T Belongs to the UPF0237 family
COOAKMDI_01714 1.2e-252 S UPF0210 protein
COOAKMDI_01715 2.9e-114 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COOAKMDI_01716 5.5e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
COOAKMDI_01717 1.3e-107
COOAKMDI_01718 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOAKMDI_01719 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOAKMDI_01720 8.7e-84 T Forkhead associated domain
COOAKMDI_01721 1.1e-70 B Belongs to the OprB family
COOAKMDI_01722 2.1e-25 3.1.3.16 T Sigma factor PP2C-like phosphatases
COOAKMDI_01723 0.0 E Transglutaminase-like superfamily
COOAKMDI_01724 6.3e-224 S Protein of unknown function DUF58
COOAKMDI_01725 6.2e-177 S ATPase family associated with various cellular activities (AAA)
COOAKMDI_01726 0.0 S Fibronectin type 3 domain
COOAKMDI_01727 9.2e-259 KLT Protein tyrosine kinase
COOAKMDI_01728 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
COOAKMDI_01729 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
COOAKMDI_01730 2.5e-226 G Major Facilitator Superfamily
COOAKMDI_01731 3e-131 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COOAKMDI_01732 1e-165 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COOAKMDI_01733 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COOAKMDI_01734 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
COOAKMDI_01735 1.2e-99 ugpQ 3.1.4.46 C Domain of unknown function
COOAKMDI_01736 1.2e-159 ugpB G Bacterial extracellular solute-binding protein
COOAKMDI_01737 1e-97 ugpE G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01738 2.6e-97 ugpA P Binding-protein-dependent transport system inner membrane component
COOAKMDI_01739 1.7e-257 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COOAKMDI_01740 5.2e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COOAKMDI_01741 1e-273 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
COOAKMDI_01742 5e-254 S Domain of unknown function (DUF4143)
COOAKMDI_01743 9.3e-206 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COOAKMDI_01744 1.8e-175 ftsE D Cell division ATP-binding protein FtsE
COOAKMDI_01745 6.3e-160 ftsX D Part of the ABC transporter FtsEX involved in cellular division
COOAKMDI_01746 1.9e-29 usp 3.5.1.28 CBM50 D CHAP domain protein
COOAKMDI_01747 5.6e-90 L Transposase, Mutator family
COOAKMDI_01748 9.1e-173 srrA1 G Bacterial extracellular solute-binding protein
COOAKMDI_01749 3.3e-122 G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01750 1.2e-125 lacG G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01751 3.9e-184 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
COOAKMDI_01752 2.6e-222 glf 5.4.99.9 M UDP-galactopyranose mutase
COOAKMDI_01753 3.8e-21 glf 5.4.99.9 M UDP-galactopyranose mutase
COOAKMDI_01754 3.7e-22 S Domain of unknown function (DUF4190)
COOAKMDI_01755 1.4e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
COOAKMDI_01756 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COOAKMDI_01757 2.1e-156 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
COOAKMDI_01758 4e-158 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COOAKMDI_01759 3.4e-132 ugpA P Binding-protein-dependent transport system inner membrane component
COOAKMDI_01760 4.7e-128 ugpE G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01761 6.9e-203 G Bacterial extracellular solute-binding protein
COOAKMDI_01762 1.3e-90 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COOAKMDI_01763 3.5e-77 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COOAKMDI_01764 2.4e-74 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COOAKMDI_01765 2.4e-122 L Transposase, Mutator family
COOAKMDI_01767 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COOAKMDI_01768 6.8e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COOAKMDI_01769 1.4e-111 nusG K Participates in transcription elongation, termination and antitermination
COOAKMDI_01770 5.2e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COOAKMDI_01772 2.2e-229 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
COOAKMDI_01773 3.9e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COOAKMDI_01774 3.2e-303 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COOAKMDI_01775 8.8e-40 rpmA J Ribosomal L27 protein
COOAKMDI_01776 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
COOAKMDI_01777 0.0 rne 3.1.26.12 J Ribonuclease E/G family
COOAKMDI_01778 8e-230 dapE 3.5.1.18 E Peptidase dimerisation domain
COOAKMDI_01779 3.5e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
COOAKMDI_01780 3.9e-07 mdcF S Transporter, auxin efflux carrier (AEC) family protein
COOAKMDI_01781 7.2e-77 fucU 5.1.3.29 G RbsD / FucU transport protein family
COOAKMDI_01782 4.6e-148 S Amidohydrolase
COOAKMDI_01783 1.4e-202 fucP G Major Facilitator Superfamily
COOAKMDI_01784 4.3e-141 IQ KR domain
COOAKMDI_01785 1.4e-245 4.2.1.68 M Enolase C-terminal domain-like
COOAKMDI_01786 5e-182 K Bacterial regulatory proteins, lacI family
COOAKMDI_01787 7.7e-253 V Efflux ABC transporter, permease protein
COOAKMDI_01788 4.5e-137 V ATPases associated with a variety of cellular activities
COOAKMDI_01789 3e-08 K Acetyltransferase (GNAT) family
COOAKMDI_01790 3.4e-31 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
COOAKMDI_01791 5.7e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
COOAKMDI_01792 1.1e-206 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COOAKMDI_01793 1.4e-232 hom 1.1.1.3 E Homoserine dehydrogenase
COOAKMDI_01794 1.9e-292 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COOAKMDI_01795 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COOAKMDI_01796 4.3e-172 K LysR substrate binding domain protein
COOAKMDI_01797 2.3e-245 patB 4.4.1.8 E Aminotransferase, class I II
COOAKMDI_01798 4.1e-253 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COOAKMDI_01799 8.4e-254 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
COOAKMDI_01800 2.2e-273 pip S YhgE Pip domain protein
COOAKMDI_01801 0.0 pip S YhgE Pip domain protein
COOAKMDI_01802 8.4e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
COOAKMDI_01803 7.5e-59 S Protein of unknown function (DUF4235)
COOAKMDI_01804 4.2e-135 G Phosphoglycerate mutase family
COOAKMDI_01805 2.5e-250 amyE G Bacterial extracellular solute-binding protein
COOAKMDI_01806 1.4e-181 K Psort location Cytoplasmic, score
COOAKMDI_01807 7.4e-147 msmF G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01808 4.4e-152 rafG G ABC transporter permease
COOAKMDI_01809 1e-100 S Protein of unknown function, DUF624
COOAKMDI_01810 1.6e-256 aroP E aromatic amino acid transport protein AroP K03293
COOAKMDI_01811 2.3e-122 V ABC transporter
COOAKMDI_01812 0.0 V FtsX-like permease family
COOAKMDI_01813 8.9e-268 cycA E Amino acid permease
COOAKMDI_01814 7.8e-78 ydgJ K helix_turn_helix multiple antibiotic resistance protein
COOAKMDI_01815 0.0 lmrA1 V ABC transporter, ATP-binding protein
COOAKMDI_01816 0.0 lmrA2 V ABC transporter transmembrane region
COOAKMDI_01817 1e-198 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COOAKMDI_01818 5.6e-232 G MFS/sugar transport protein
COOAKMDI_01820 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_01821 4.3e-146 cobB2 K Sir2 family
COOAKMDI_01822 4.8e-235 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
COOAKMDI_01823 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
COOAKMDI_01824 0.0 rafA 3.2.1.22 G Raffinose synthase or seed imbibition protein Sip1
COOAKMDI_01825 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
COOAKMDI_01826 2.9e-148 G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01827 3.5e-191 malC G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01828 1.6e-249 msmE G Bacterial extracellular solute-binding protein
COOAKMDI_01830 6.8e-233 G Protein of unknown function (DUF2961)
COOAKMDI_01831 1.5e-231 msmE G Bacterial extracellular solute-binding protein
COOAKMDI_01832 2.1e-188 K helix_turn _helix lactose operon repressor
COOAKMDI_01833 3.9e-187 K Periplasmic binding protein-like domain
COOAKMDI_01834 3.2e-153 G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01835 1.3e-139 G Binding-protein-dependent transport system inner membrane component
COOAKMDI_01836 6.8e-245 msmE7 G Bacterial extracellular solute-binding protein
COOAKMDI_01837 6.7e-226 nagC GK ROK family
COOAKMDI_01838 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
COOAKMDI_01839 3.8e-81 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COOAKMDI_01840 0.0 yjcE P Sodium/hydrogen exchanger family
COOAKMDI_01841 5.1e-147 ypfH S Phospholipase/Carboxylesterase
COOAKMDI_01842 8.2e-130
COOAKMDI_01843 3.4e-111 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
COOAKMDI_01844 1e-65
COOAKMDI_01845 3.8e-175 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COOAKMDI_01846 1.1e-167 endOF2 3.2.1.14, 3.2.1.35, 3.2.1.52, 3.2.1.96 GH18,GH20 G Glycosyl hydrolase, family 20, catalytic domain
COOAKMDI_01847 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
COOAKMDI_01848 5.3e-17 K helix_turn _helix lactose operon repressor
COOAKMDI_01849 5.4e-84 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
COOAKMDI_01850 3.5e-288 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
COOAKMDI_01851 7e-227 guxA1 3.2.1.91 GH6 G Domain of unknown function (DUF4091)
COOAKMDI_01852 4e-46 L Transposase
COOAKMDI_01853 5.7e-10 L Transposase DDE domain
COOAKMDI_01854 7e-74 G Binding-protein-dependent transport systems inner membrane component
COOAKMDI_01855 8e-78 G PFAM binding-protein-dependent transport systems inner membrane component
COOAKMDI_01856 1.3e-86 G Extracellular solute-binding protein
COOAKMDI_01857 1.9e-59 K Periplasmic binding protein domain
COOAKMDI_01858 1.5e-255 S Domain of unknown function (DUF4143)
COOAKMDI_01859 1.4e-196 EGP Major facilitator Superfamily
COOAKMDI_01860 4.1e-173 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COOAKMDI_01861 5.3e-267 KLT Domain of unknown function (DUF4032)
COOAKMDI_01862 1.8e-209 ugpC E Belongs to the ABC transporter superfamily
COOAKMDI_01863 2.4e-207 2.4.1.166 GT2 M Glycosyltransferase like family 2
COOAKMDI_01864 3.7e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COOAKMDI_01866 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COOAKMDI_01867 3.8e-81 nrdI F Probably involved in ribonucleotide reductase function
COOAKMDI_01868 4.1e-43 nrdH O Glutaredoxin
COOAKMDI_01869 7e-234 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
COOAKMDI_01870 1.4e-113 K Helix-turn-helix XRE-family like proteins
COOAKMDI_01871 1.3e-125 S Protein of unknown function (DUF3990)
COOAKMDI_01872 6.4e-108 kcsA U Ion channel
COOAKMDI_01873 1.9e-203 S AAA ATPase domain
COOAKMDI_01874 0.0 KLT Protein tyrosine kinase
COOAKMDI_01875 2.7e-132 O Thioredoxin
COOAKMDI_01877 2.6e-208 S G5
COOAKMDI_01878 1e-165 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COOAKMDI_01879 6.5e-176 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COOAKMDI_01880 3.1e-110 S LytR cell envelope-related transcriptional attenuator
COOAKMDI_01881 9.7e-277 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
COOAKMDI_01882 9.3e-117 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
COOAKMDI_01883 0.0
COOAKMDI_01884 2.4e-208 murJ KLT MviN-like protein
COOAKMDI_01885 0.0 murJ KLT MviN-like protein
COOAKMDI_01886 1.3e-185 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COOAKMDI_01887 3.7e-217 parB K Belongs to the ParB family
COOAKMDI_01888 7.8e-177 parA D CobQ CobB MinD ParA nucleotide binding domain protein
COOAKMDI_01889 1.4e-121 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COOAKMDI_01890 1.7e-93 jag S Putative single-stranded nucleic acids-binding domain
COOAKMDI_01891 1.5e-175 yidC U Membrane protein insertase, YidC Oxa1 family
COOAKMDI_01892 4e-33 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COOAKMDI_01893 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
COOAKMDI_01894 4.3e-283 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COOAKMDI_01896 7.6e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COOAKMDI_01897 3.2e-223 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COOAKMDI_01898 6.7e-81 S Protein of unknown function (DUF721)
COOAKMDI_01899 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COOAKMDI_01900 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COOAKMDI_01901 2.1e-81 S Transmembrane domain of unknown function (DUF3566)
COOAKMDI_01902 1.9e-272 S ATPase domain predominantly from Archaea
COOAKMDI_01904 7.4e-250 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
COOAKMDI_01905 9e-119 cpdA 2.1.2.2, 3.1.3.48, 3.1.4.17, 3.1.4.53 T protein tyrosine phosphatase activity
COOAKMDI_01906 5.1e-103 3.6.3.29, 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COOAKMDI_01907 1.8e-189 afuB2 P Binding-protein-dependent transport systems inner membrane component
COOAKMDI_01908 1.9e-131 afuA P Bacterial extracellular solute-binding protein
COOAKMDI_01909 1.8e-68 K Transcriptional regulator, rpir family
COOAKMDI_01910 5.3e-28 S addiction module toxin, RelE StbE family
COOAKMDI_01911 1.3e-28 relB L RelB antitoxin
COOAKMDI_01912 3.7e-34 tnpA L Transposase
COOAKMDI_01913 1.5e-38
COOAKMDI_01915 6.6e-11 L Phage integrase family
COOAKMDI_01918 6.4e-70 cpdB 3.1.3.6, 3.1.4.16 F Calcineurin-like phosphoesterase
COOAKMDI_01919 1.7e-81 3.6.1.63 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_01920 6.9e-78 phnE 3.6.1.63 U Binding-protein-dependent transport system inner membrane component
COOAKMDI_01921 2e-82 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
COOAKMDI_01922 1.8e-114 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
COOAKMDI_01923 2.4e-36 K Helix-turn-helix domain, rpiR family
COOAKMDI_01924 9.7e-31 S phosphoglycolate phosphatase activity
COOAKMDI_01925 1.1e-202 S Domain of unknown function (DUF4143)
COOAKMDI_01926 8.8e-146 S Protein of unknown function DUF45
COOAKMDI_01927 5.9e-93 K FCD
COOAKMDI_01928 1.8e-214 EG GntP family permease
COOAKMDI_01929 6.6e-88 gntK 1.1.1.343, 1.1.1.44, 2.7.1.12, 2.7.1.71 F Shikimate kinase
COOAKMDI_01930 4e-151 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
COOAKMDI_01931 1.6e-82 dps P Belongs to the Dps family
COOAKMDI_01932 1e-235 ytfL P Transporter associated domain
COOAKMDI_01933 9.1e-201 S AAA ATPase domain
COOAKMDI_01934 9.6e-70 V Forkhead associated domain
COOAKMDI_01935 1.6e-120 cah 4.2.1.1 P Reversible hydration of carbon dioxide
COOAKMDI_01936 3.8e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
COOAKMDI_01937 0.0 trxB1 1.8.1.9 C Thioredoxin domain
COOAKMDI_01938 9.5e-239 yhjX EGP Major facilitator Superfamily
COOAKMDI_01939 7.3e-68 S Psort location Cytoplasmic, score
COOAKMDI_01940 2.1e-15 tetP J elongation factor G
COOAKMDI_01941 2.7e-195 V FtsX-like permease family
COOAKMDI_01942 1.1e-63 S Domain of unknown function (DUF4418)
COOAKMDI_01943 0.0 pcrA 3.6.4.12 L DNA helicase
COOAKMDI_01944 1e-102 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COOAKMDI_01945 1e-238 pbuX F Permease family
COOAKMDI_01946 2.8e-31 yozG K Cro/C1-type HTH DNA-binding domain
COOAKMDI_01947 4.6e-39 S Protein of unknown function (DUF2975)
COOAKMDI_01948 6.2e-159 I Serine aminopeptidase, S33
COOAKMDI_01949 1e-115 M pfam nlp p60
COOAKMDI_01950 5.1e-30 M pfam nlp p60
COOAKMDI_01951 1e-66 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COOAKMDI_01952 2.4e-107 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
COOAKMDI_01953 4.1e-110 3.4.13.21 E Peptidase family S51
COOAKMDI_01954 9.2e-191
COOAKMDI_01955 9.5e-107
COOAKMDI_01956 2.3e-23 E GDSL-like Lipase/Acylhydrolase family
COOAKMDI_01957 3.1e-24 E GDSL-like Lipase/Acylhydrolase family
COOAKMDI_01958 2.2e-32 E GDSL-like Lipase/Acylhydrolase family
COOAKMDI_01959 2e-89 K Helix-turn-helix domain
COOAKMDI_01960 3.2e-101 S PIN domain
COOAKMDI_01961 1e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
COOAKMDI_01962 2.9e-249 V ABC-2 family transporter protein
COOAKMDI_01963 1.7e-224 V ABC-2 family transporter protein
COOAKMDI_01964 2.5e-186 V ATPases associated with a variety of cellular activities
COOAKMDI_01965 1.8e-10 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
COOAKMDI_01966 4.4e-226 T Histidine kinase
COOAKMDI_01967 8.6e-103 K helix_turn_helix, Lux Regulon
COOAKMDI_01968 3e-113 MA20_27875 P Protein of unknown function DUF47
COOAKMDI_01969 4.1e-187 pit P Phosphate transporter family
COOAKMDI_01970 6.8e-27 ybdD S Selenoprotein, putative
COOAKMDI_01971 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
COOAKMDI_01972 3e-256 nplT G Alpha amylase, catalytic domain
COOAKMDI_01973 4.3e-53 K WHG domain
COOAKMDI_01974 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
COOAKMDI_01975 7.1e-234 rutG F Permease family
COOAKMDI_01976 2.7e-162 3.1.3.73 G Phosphoglycerate mutase family
COOAKMDI_01977 6.3e-105 3.1.3.27 E haloacid dehalogenase-like hydrolase
COOAKMDI_01978 3.4e-76 S Helix-turn-helix
COOAKMDI_01979 1.3e-197 S Short C-terminal domain
COOAKMDI_01980 2.4e-39
COOAKMDI_01981 2.7e-224
COOAKMDI_01982 4.2e-77 K Psort location Cytoplasmic, score
COOAKMDI_01983 2.5e-276 KLT Protein tyrosine kinase
COOAKMDI_01984 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
COOAKMDI_01985 5e-11
COOAKMDI_01986 4.4e-121 K Bacterial regulatory proteins, tetR family
COOAKMDI_01987 3.2e-218 G Transmembrane secretion effector
COOAKMDI_01988 1.1e-242 S HipA-like C-terminal domain
COOAKMDI_01989 1.1e-37 L RelB antitoxin
COOAKMDI_01990 1.7e-12 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COOAKMDI_01991 2.5e-67 S Cupin 2, conserved barrel domain protein
COOAKMDI_01992 2.9e-56 ksgA 2.1.1.182 J Methyltransferase domain
COOAKMDI_01993 3.1e-60 yccF S Inner membrane component domain
COOAKMDI_01994 6.5e-232 XK27_00240 K Fic/DOC family
COOAKMDI_01995 6.8e-26 2.7.7.7 L Transposase, Mutator family
COOAKMDI_01996 0.0 drrC L ABC transporter
COOAKMDI_01997 3.6e-244 V MatE
COOAKMDI_01999 2.1e-32 S rRNA binding
COOAKMDI_02000 1.7e-162 K Arac family
COOAKMDI_02001 4.7e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COOAKMDI_02002 5.9e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COOAKMDI_02003 3.7e-279 pip 3.4.11.5 S alpha/beta hydrolase fold
COOAKMDI_02004 0.0 tcsS2 T Histidine kinase
COOAKMDI_02005 6.4e-133 K helix_turn_helix, Lux Regulon
COOAKMDI_02006 0.0 MV MacB-like periplasmic core domain
COOAKMDI_02007 2.3e-146 V ABC transporter, ATP-binding protein
COOAKMDI_02008 2.1e-249 metY 2.5.1.49 E Aminotransferase class-V
COOAKMDI_02009 6.8e-164 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
COOAKMDI_02010 9.6e-94 yraN L Belongs to the UPF0102 family
COOAKMDI_02011 3e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
COOAKMDI_02012 2e-305 dprA 5.99.1.2 LU DNA recombination-mediator protein A
COOAKMDI_02013 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
COOAKMDI_02014 3.4e-180 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
COOAKMDI_02015 1.1e-110 safC S O-methyltransferase
COOAKMDI_02016 2.6e-153 fmt2 3.2.2.10 S Belongs to the LOG family
COOAKMDI_02017 3.2e-227 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
COOAKMDI_02020 1.2e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COOAKMDI_02021 6.1e-123 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COOAKMDI_02022 3.8e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COOAKMDI_02023 2.1e-53
COOAKMDI_02024 1.5e-232 clcA_2 P Voltage gated chloride channel
COOAKMDI_02025 4.4e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COOAKMDI_02026 1.8e-248 rnd 3.1.13.5 J 3'-5' exonuclease
COOAKMDI_02027 3.4e-120 S Protein of unknown function (DUF3000)
COOAKMDI_02028 1.9e-174 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COOAKMDI_02029 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
COOAKMDI_02030 8.5e-34
COOAKMDI_02031 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
COOAKMDI_02032 2.7e-224 S Peptidase dimerisation domain
COOAKMDI_02033 1.3e-112 metI P Binding-protein-dependent transport system inner membrane component
COOAKMDI_02034 1.1e-217 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COOAKMDI_02035 2.1e-169 metQ P NLPA lipoprotein
COOAKMDI_02036 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
COOAKMDI_02037 7.4e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COOAKMDI_02038 6.5e-34 XK27_07020 S Domain of unknown function (DUF1846)
COOAKMDI_02039 4.4e-277 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
COOAKMDI_02040 2.4e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COOAKMDI_02042 3e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COOAKMDI_02043 2.3e-63 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COOAKMDI_02044 1.5e-121 3.1.3.85 G Phosphoglycerate mutase family
COOAKMDI_02047 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COOAKMDI_02048 7.2e-228 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COOAKMDI_02049 1.1e-248 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
COOAKMDI_02050 1.3e-197 ykiI
COOAKMDI_02052 1.2e-13 K Putative zinc ribbon domain
COOAKMDI_02053 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
COOAKMDI_02054 7.5e-126 3.6.1.13 L NUDIX domain
COOAKMDI_02055 3.9e-178 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
COOAKMDI_02056 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COOAKMDI_02057 2.9e-121 pdtaR T Response regulator receiver domain protein
COOAKMDI_02058 6.7e-150 L Phage integrase family
COOAKMDI_02061 2.8e-18
COOAKMDI_02062 8.3e-11
COOAKMDI_02063 9.3e-10 S Protein of unknown function (DUF1778)
COOAKMDI_02064 9.8e-38
COOAKMDI_02065 5.4e-11
COOAKMDI_02068 3.8e-127 mltE2 M Bacteriophage peptidoglycan hydrolase
COOAKMDI_02071 4e-68
COOAKMDI_02072 3.1e-140
COOAKMDI_02078 5.5e-68 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
COOAKMDI_02079 4.4e-56
COOAKMDI_02080 6.3e-07 S CAAX protease self-immunity
COOAKMDI_02081 1e-30
COOAKMDI_02082 0.0 XK27_00515 D Cell surface antigen C-terminus
COOAKMDI_02083 1.7e-92 M domain protein
COOAKMDI_02084 1.9e-88 M Listeria-Bacteroides repeat domain (List_Bact_rpt)
COOAKMDI_02085 4.7e-49 3.4.22.70 M Sortase family
COOAKMDI_02086 3.7e-52 D nuclear chromosome segregation
COOAKMDI_02087 1.6e-14 higA K Helix-turn-helix XRE-family like proteins
COOAKMDI_02090 4.9e-18
COOAKMDI_02091 1.1e-27
COOAKMDI_02093 7.6e-51
COOAKMDI_02095 4.4e-29 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COOAKMDI_02096 3.1e-40 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
COOAKMDI_02101 8.7e-192 U Type IV secretory pathway, VirB4
COOAKMDI_02102 2.8e-218 U TraM recognition site of TraD and TraG
COOAKMDI_02107 2.5e-67
COOAKMDI_02109 5.6e-10 S Helix-turn-helix domain
COOAKMDI_02110 1.1e-215 S Helix-turn-helix domain
COOAKMDI_02111 4.7e-84 S Transcription factor WhiB
COOAKMDI_02112 1.4e-104 parA D AAA domain
COOAKMDI_02113 8.9e-40
COOAKMDI_02115 7e-121 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COOAKMDI_02116 7.8e-129 V ATPases associated with a variety of cellular activities
COOAKMDI_02117 2.7e-168 V MacB-like periplasmic core domain
COOAKMDI_02118 6e-88
COOAKMDI_02119 0.0 XK27_00515 D Cell surface antigen C-terminus
COOAKMDI_02120 5.5e-32
COOAKMDI_02121 3.1e-160 S HipA-like C-terminal domain
COOAKMDI_02122 4.5e-10
COOAKMDI_02123 0.0 traA 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COOAKMDI_02125 1.1e-17
COOAKMDI_02131 1.8e-21 relB L RelB antitoxin
COOAKMDI_02133 3.2e-21 L single-stranded DNA binding
COOAKMDI_02135 5.6e-12 L Domain of unknown function (DUF3846)
COOAKMDI_02139 1.1e-13
COOAKMDI_02140 5.4e-65 S Glutamine amidotransferases class-II
COOAKMDI_02141 8.4e-76
COOAKMDI_02142 3.2e-48 K sequence-specific DNA binding
COOAKMDI_02143 7.7e-68 L Helix-turn-helix domain
COOAKMDI_02144 1.8e-111 insK L Integrase core domain
COOAKMDI_02145 4.7e-15
COOAKMDI_02146 1.3e-25 S Protein of unknown function (DUF1778)
COOAKMDI_02147 7.3e-59 K Acetyltransferase (GNAT) family
COOAKMDI_02148 1.5e-07 K transcriptional regulator, XRE family
COOAKMDI_02149 4.8e-155 recQ 3.6.4.12, 5.99.1.2 F RecQ zinc-binding
COOAKMDI_02150 4.8e-73 L helicase
COOAKMDI_02152 3.3e-76 K Psort location Cytoplasmic, score
COOAKMDI_02153 2.1e-100 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
COOAKMDI_02157 1.2e-17
COOAKMDI_02158 4.5e-40
COOAKMDI_02161 2.3e-35
COOAKMDI_02162 1.5e-56 K Helix-turn-helix domain
COOAKMDI_02167 5.8e-49 ydhQ 2.7.11.1 MU cell adhesion
COOAKMDI_02168 2.3e-08 ycf55 KT response regulator
COOAKMDI_02172 1.3e-26 aspA 3.6.1.13 L NUDIX domain
COOAKMDI_02173 1.6e-274 pyk 2.7.1.40 G Pyruvate kinase
COOAKMDI_02174 1.4e-165 terC P Integral membrane protein, TerC family
COOAKMDI_02175 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COOAKMDI_02176 3.3e-55 2.1.1.80, 3.1.1.61 T Histidine kinase
COOAKMDI_02177 4e-63 K helix_turn_helix, Lux Regulon
COOAKMDI_02179 6.1e-144 XK27_10205
COOAKMDI_02180 1.5e-72 V ABC transporter
COOAKMDI_02181 1.5e-72 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COOAKMDI_02182 8.6e-252 rpsA J Ribosomal protein S1
COOAKMDI_02183 4e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COOAKMDI_02184 4.4e-174 P Zinc-uptake complex component A periplasmic
COOAKMDI_02185 7e-164 znuC P ATPases associated with a variety of cellular activities
COOAKMDI_02186 1.2e-136 znuB U ABC 3 transport family
COOAKMDI_02187 5.1e-90 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
COOAKMDI_02188 1.6e-100 carD K CarD-like/TRCF domain
COOAKMDI_02189 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COOAKMDI_02190 5e-128 T Response regulator receiver domain protein
COOAKMDI_02191 3.1e-190 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
COOAKMDI_02192 7.4e-62 KT Peptidase S24-like
COOAKMDI_02193 1.3e-56 ctsW S Phosphoribosyl transferase domain
COOAKMDI_02194 7.5e-149 cof 5.2.1.8 T Eukaryotic phosphomannomutase
COOAKMDI_02195 3.3e-64 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
COOAKMDI_02196 5.8e-267
COOAKMDI_02197 0.0 S Glycosyl transferase, family 2
COOAKMDI_02198 4.7e-56 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
COOAKMDI_02199 5e-164 K Cell envelope-related transcriptional attenuator domain
COOAKMDI_02200 0.0 D FtsK/SpoIIIE family
COOAKMDI_02201 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
COOAKMDI_02202 5.6e-278 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
COOAKMDI_02203 3.4e-132 yplQ S Haemolysin-III related
COOAKMDI_02204 5.7e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COOAKMDI_02205 1.5e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
COOAKMDI_02206 1.2e-277 sdaA 4.3.1.17 E Serine dehydratase alpha chain
COOAKMDI_02207 1.2e-92
COOAKMDI_02208 9.6e-178 L Transposase
COOAKMDI_02209 5.1e-59 L Phage integrase family
COOAKMDI_02210 1.6e-205 L Transposase and inactivated derivatives IS30 family
COOAKMDI_02212 4.6e-22 K helix_turn_helix, Lux Regulon
COOAKMDI_02214 4.8e-11
COOAKMDI_02215 3.2e-93 V AAA domain, putative AbiEii toxin, Type IV TA system
COOAKMDI_02216 2e-56 V Transport permease protein
COOAKMDI_02217 2.7e-26 U Transport permease protein
COOAKMDI_02218 3e-228 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_02219 2e-155 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
COOAKMDI_02220 4.4e-111
COOAKMDI_02221 3e-228 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_02222 3e-228 2.7.7.7 L Transposase and inactivated derivatives
COOAKMDI_02224 0.0 yjjK S ATP-binding cassette protein, ChvD family
COOAKMDI_02225 1.4e-167 tesB I Thioesterase-like superfamily
COOAKMDI_02226 2.1e-91 S Protein of unknown function (DUF3180)
COOAKMDI_02227 2.4e-267 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COOAKMDI_02228 5.1e-159 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
COOAKMDI_02229 5.8e-106 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
COOAKMDI_02231 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COOAKMDI_02232 1.8e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COOAKMDI_02233 7.4e-214 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COOAKMDI_02234 2.9e-255 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
COOAKMDI_02235 7.2e-295
COOAKMDI_02236 1e-141 natA V ATPases associated with a variety of cellular activities
COOAKMDI_02237 2.6e-233 epsG M Glycosyl transferase family 21
COOAKMDI_02238 1.2e-253 S AI-2E family transporter
COOAKMDI_02239 3.1e-175 3.4.14.13 M Glycosyltransferase like family 2
COOAKMDI_02240 1.2e-203 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
COOAKMDI_02241 3.2e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
COOAKMDI_02244 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COOAKMDI_02245 3.2e-158 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COOAKMDI_02247 4.6e-189 3.6.4.12 K Divergent AAA domain protein
COOAKMDI_02250 4.2e-07 S Protein of unknown function (DUF1648)
COOAKMDI_02252 8.7e-128 L Transposase
COOAKMDI_02253 8.4e-168 L Transposase
COOAKMDI_02254 5.4e-153 L Transposase
COOAKMDI_02256 1.2e-154 cbiO V ATPases associated with a variety of cellular activities
COOAKMDI_02257 1.6e-188 lanT 3.6.3.27 V ABC transporter
COOAKMDI_02258 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COOAKMDI_02259 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
COOAKMDI_02260 2.3e-246 pbuO S Permease family
COOAKMDI_02261 5.5e-139 3.2.1.8 S alpha beta
COOAKMDI_02262 3.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COOAKMDI_02263 1.1e-33 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COOAKMDI_02264 1e-185 T Forkhead associated domain
COOAKMDI_02265 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
COOAKMDI_02266 3e-30
COOAKMDI_02267 2.6e-88 flgA NO SAF
COOAKMDI_02268 9.5e-31 fmdB S Putative regulatory protein
COOAKMDI_02269 2.7e-107 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
COOAKMDI_02270 3.7e-125 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
COOAKMDI_02271 2.3e-172
COOAKMDI_02272 6.7e-47 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COOAKMDI_02273 4.2e-66 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
COOAKMDI_02277 4.1e-25 rpmG J Ribosomal protein L33
COOAKMDI_02278 5.7e-217 murB 1.3.1.98 M Cell wall formation
COOAKMDI_02279 4.4e-267 E aromatic amino acid transport protein AroP K03293
COOAKMDI_02280 1.7e-59 fdxA C 4Fe-4S binding domain
COOAKMDI_02281 1.1e-212 dapC E Aminotransferase class I and II
COOAKMDI_02282 1e-232 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COOAKMDI_02284 1.1e-192 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COOAKMDI_02285 3.8e-111 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
COOAKMDI_02286 7.6e-109
COOAKMDI_02287 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
COOAKMDI_02288 1.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COOAKMDI_02289 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
COOAKMDI_02290 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
COOAKMDI_02291 4e-176 tdh 1.1.1.14 C Zinc-binding dehydrogenase
COOAKMDI_02292 4.5e-223 EGP Major facilitator Superfamily
COOAKMDI_02293 2.1e-67 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COOAKMDI_02294 1e-216 EGP Major facilitator Superfamily
COOAKMDI_02295 7.1e-192 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
COOAKMDI_02296 2.1e-136 rhaR_1 K helix_turn_helix, arabinose operon control protein
COOAKMDI_02298 5.7e-219 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
COOAKMDI_02299 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COOAKMDI_02300 3.9e-70 ywiC S YwiC-like protein
COOAKMDI_02301 1.5e-143 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
COOAKMDI_02302 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
COOAKMDI_02303 1.1e-115 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COOAKMDI_02304 1.2e-115 rplD J Forms part of the polypeptide exit tunnel
COOAKMDI_02305 3.4e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COOAKMDI_02306 8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COOAKMDI_02307 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COOAKMDI_02308 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COOAKMDI_02309 1.6e-98 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COOAKMDI_02310 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COOAKMDI_02311 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
COOAKMDI_02312 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COOAKMDI_02313 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COOAKMDI_02314 5.1e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COOAKMDI_02315 4.4e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COOAKMDI_02316 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COOAKMDI_02317 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COOAKMDI_02318 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COOAKMDI_02319 2.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COOAKMDI_02320 1.5e-95 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COOAKMDI_02321 9.2e-26 rpmD J Ribosomal protein L30p/L7e
COOAKMDI_02322 2.4e-75 rplO J binds to the 23S rRNA
COOAKMDI_02323 5.2e-248 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COOAKMDI_02324 6.5e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COOAKMDI_02325 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COOAKMDI_02326 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COOAKMDI_02327 3.6e-61 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COOAKMDI_02328 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COOAKMDI_02329 2e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COOAKMDI_02330 7.7e-62 rplQ J Ribosomal protein L17
COOAKMDI_02331 1.4e-167 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COOAKMDI_02332 0.0 gcs2 S A circularly permuted ATPgrasp
COOAKMDI_02333 5.2e-150 E Transglutaminase/protease-like homologues
COOAKMDI_02334 1e-219 S Psort location Cytoplasmic, score
COOAKMDI_02336 2.6e-12 L Integrase core domain
COOAKMDI_02337 8.7e-128 L Transposase
COOAKMDI_02338 5.6e-127
COOAKMDI_02339 1.1e-51
COOAKMDI_02340 2.3e-14
COOAKMDI_02341 8.7e-128 L Transposase
COOAKMDI_02342 2.1e-115
COOAKMDI_02343 4e-101
COOAKMDI_02346 7.9e-217 L Transposase, Mutator family
COOAKMDI_02347 2.8e-87 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COOAKMDI_02348 3.5e-77 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COOAKMDI_02349 2.8e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COOAKMDI_02350 2.4e-92 M1-431 S Protein of unknown function (DUF1706)
COOAKMDI_02351 5.9e-128 malK P Belongs to the ABC transporter superfamily
COOAKMDI_02352 9.5e-103 gtsB G PFAM Binding-protein-dependent transport system inner membrane component
COOAKMDI_02353 3.8e-100 gtsC P Binding-protein-dependent transport system inner membrane component
COOAKMDI_02354 6.6e-118 YSH1 S Metallo-beta-lactamase superfamily
COOAKMDI_02355 2.7e-140 G Extracellular solute-binding protein
COOAKMDI_02356 5.2e-32 3.1.3.18 S phosphoglycolate phosphatase activity
COOAKMDI_02357 1.3e-202 G Glycosyl hydrolase family 20, domain 2
COOAKMDI_02358 1.8e-223 G Bacterial extracellular solute-binding protein
COOAKMDI_02359 5.8e-167 L Helix-turn-helix domain
COOAKMDI_02360 9e-17 L Resolvase, N terminal domain
COOAKMDI_02361 1.3e-211 phoN I PAP2 superfamily
COOAKMDI_02362 5.3e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COOAKMDI_02363 3.5e-77 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COOAKMDI_02364 6.4e-91 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COOAKMDI_02365 1.4e-226 G Bacterial extracellular solute-binding protein
COOAKMDI_02366 8.9e-247 G Bacterial extracellular solute-binding protein
COOAKMDI_02367 6e-137 nanL 4.3.3.7 EM Dihydrodipicolinate synthetase family
COOAKMDI_02368 4.2e-124 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
COOAKMDI_02369 3.3e-233 G Bacterial extracellular solute-binding protein
COOAKMDI_02370 1.6e-150 G Binding-protein-dependent transport system inner membrane component
COOAKMDI_02371 5.1e-152 G Binding-protein-dependent transport system inner membrane component
COOAKMDI_02372 2.3e-95 S Protein of unknown function, DUF624
COOAKMDI_02373 1.8e-242 4.2.1.68 M Enolase C-terminal domain-like
COOAKMDI_02374 3.9e-142 IQ KR domain
COOAKMDI_02375 4.7e-152 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
COOAKMDI_02376 2.4e-69 fucU 5.1.3.29 G RbsD / FucU transport protein family
COOAKMDI_02377 2.8e-255 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
COOAKMDI_02378 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
COOAKMDI_02379 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
COOAKMDI_02380 2.3e-271 lacS G Psort location CytoplasmicMembrane, score 10.00
COOAKMDI_02381 3.4e-259 lacS G Psort location CytoplasmicMembrane, score 10.00
COOAKMDI_02382 1.4e-116
COOAKMDI_02383 2.7e-211 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
COOAKMDI_02384 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COOAKMDI_02385 1.7e-243 S Calcineurin-like phosphoesterase
COOAKMDI_02386 4.5e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
COOAKMDI_02387 1.1e-269 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COOAKMDI_02388 1.6e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COOAKMDI_02389 4.1e-206 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
COOAKMDI_02390 3.7e-146 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)