ORF_ID e_value Gene_name EC_number CAZy COGs Description
APOCAHHA_00001 4.5e-08
APOCAHHA_00008 2.4e-75 ctsR K Belongs to the CtsR family
APOCAHHA_00009 3.8e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
APOCAHHA_00010 1e-201 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
APOCAHHA_00011 0.0 clpC O Belongs to the ClpA ClpB family
APOCAHHA_00012 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APOCAHHA_00013 2.4e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
APOCAHHA_00014 8.5e-137 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
APOCAHHA_00015 2.6e-49 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
APOCAHHA_00016 1.6e-123 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
APOCAHHA_00017 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
APOCAHHA_00018 7.4e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APOCAHHA_00019 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
APOCAHHA_00020 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
APOCAHHA_00021 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APOCAHHA_00022 9.8e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APOCAHHA_00023 4.7e-88 yacP S RNA-binding protein containing a PIN domain
APOCAHHA_00024 4.4e-115 sigH K Belongs to the sigma-70 factor family
APOCAHHA_00025 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APOCAHHA_00026 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
APOCAHHA_00027 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APOCAHHA_00028 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APOCAHHA_00029 1.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APOCAHHA_00030 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APOCAHHA_00031 9.1e-107 rsmC 2.1.1.172 J Methyltransferase
APOCAHHA_00032 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOCAHHA_00033 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOCAHHA_00034 3e-32 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
APOCAHHA_00035 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APOCAHHA_00036 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APOCAHHA_00037 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APOCAHHA_00038 4.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APOCAHHA_00039 2.8e-171 ybaC 3.4.11.5 S Alpha/beta hydrolase family
APOCAHHA_00040 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
APOCAHHA_00041 1.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APOCAHHA_00042 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
APOCAHHA_00043 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APOCAHHA_00044 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APOCAHHA_00045 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APOCAHHA_00046 1.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APOCAHHA_00047 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APOCAHHA_00048 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APOCAHHA_00049 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
APOCAHHA_00050 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APOCAHHA_00051 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APOCAHHA_00052 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APOCAHHA_00053 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APOCAHHA_00054 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APOCAHHA_00055 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APOCAHHA_00056 3.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APOCAHHA_00057 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APOCAHHA_00058 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APOCAHHA_00059 1.9e-23 rpmD J Ribosomal protein L30
APOCAHHA_00060 6.9e-72 rplO J binds to the 23S rRNA
APOCAHHA_00061 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APOCAHHA_00062 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APOCAHHA_00063 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
APOCAHHA_00064 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APOCAHHA_00065 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
APOCAHHA_00066 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APOCAHHA_00067 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APOCAHHA_00068 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOCAHHA_00069 3.6e-58 rplQ J Ribosomal protein L17
APOCAHHA_00070 7.3e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOCAHHA_00071 1.7e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOCAHHA_00072 7.5e-117 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOCAHHA_00073 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APOCAHHA_00074 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APOCAHHA_00075 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
APOCAHHA_00076 7.2e-141 ybaJ Q Methyltransferase domain
APOCAHHA_00077 2.8e-65 ybaK S Protein of unknown function (DUF2521)
APOCAHHA_00078 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOCAHHA_00079 9.7e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
APOCAHHA_00080 3.4e-84 gerD
APOCAHHA_00081 4.3e-101 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
APOCAHHA_00082 6e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
APOCAHHA_00083 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_00086 2e-08
APOCAHHA_00090 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_00091 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_00092 5.4e-175 glcP G Major Facilitator Superfamily
APOCAHHA_00093 6.5e-232 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOCAHHA_00094 2.2e-155 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
APOCAHHA_00095 3.1e-171 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
APOCAHHA_00096 3.3e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
APOCAHHA_00097 5.4e-162 ybaS 1.1.1.58 S Na -dependent transporter
APOCAHHA_00098 4e-128 ybbA S Putative esterase
APOCAHHA_00099 2.8e-177 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_00100 6.9e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_00101 1.4e-162 feuA P Iron-uptake system-binding protein
APOCAHHA_00102 3.7e-293 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
APOCAHHA_00103 2.1e-235 ybbC 3.2.1.52 S protein conserved in bacteria
APOCAHHA_00104 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
APOCAHHA_00105 1e-243 yfeW 3.4.16.4 V Belongs to the UPF0214 family
APOCAHHA_00106 1.1e-227 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOCAHHA_00107 1.2e-144 ybbH K transcriptional
APOCAHHA_00108 1.8e-154 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APOCAHHA_00109 1.3e-84 ybbJ J acetyltransferase
APOCAHHA_00110 2.6e-74 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
APOCAHHA_00116 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_00117 9.1e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
APOCAHHA_00118 1.3e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APOCAHHA_00119 2.2e-220 ybbR S protein conserved in bacteria
APOCAHHA_00120 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APOCAHHA_00121 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APOCAHHA_00122 4.3e-169 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APOCAHHA_00123 4.3e-115 adaA 3.2.2.21 K Transcriptional regulator
APOCAHHA_00124 3.5e-86 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APOCAHHA_00125 8e-261 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APOCAHHA_00126 0.0 ybcC S Belongs to the UPF0753 family
APOCAHHA_00127 3e-82 can 4.2.1.1 P carbonic anhydrase
APOCAHHA_00128 6.4e-42
APOCAHHA_00129 5.2e-57 ybcI S Uncharacterized conserved protein (DUF2294)
APOCAHHA_00130 2.5e-57 ybzH K Helix-turn-helix domain
APOCAHHA_00131 2e-198 ybcL EGP Major facilitator Superfamily
APOCAHHA_00132 7.3e-89 C HEAT repeats
APOCAHHA_00133 1.2e-76 txn CO Thioredoxin-like
APOCAHHA_00134 3.3e-175 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APOCAHHA_00135 5.2e-119 T Transcriptional regulatory protein, C terminal
APOCAHHA_00136 1.2e-153 T His Kinase A (phospho-acceptor) domain
APOCAHHA_00138 2.2e-134 KLT Protein tyrosine kinase
APOCAHHA_00139 1.6e-149 ybdN
APOCAHHA_00140 2.4e-204 ybdO S Domain of unknown function (DUF4885)
APOCAHHA_00141 4.9e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
APOCAHHA_00142 3.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
APOCAHHA_00143 4.9e-30 ybxH S Family of unknown function (DUF5370)
APOCAHHA_00144 2.8e-148 ybxI 3.5.2.6 V beta-lactamase
APOCAHHA_00145 6.4e-240 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
APOCAHHA_00146 4.9e-41 ybyB
APOCAHHA_00147 4.4e-289 ybeC E amino acid
APOCAHHA_00148 4.8e-275 nptA P COG1283 Na phosphate symporter
APOCAHHA_00149 1.8e-156 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APOCAHHA_00150 4e-256 glpT G -transporter
APOCAHHA_00151 4.4e-31 S Protein of unknown function (DUF2651)
APOCAHHA_00152 1.1e-164 ybfA 3.4.15.5 K FR47-like protein
APOCAHHA_00153 2.8e-219 ybfB G COG0477 Permeases of the major facilitator superfamily
APOCAHHA_00155 1e-157 ybfH EG EamA-like transporter family
APOCAHHA_00156 4.4e-144 msmR K AraC-like ligand binding domain
APOCAHHA_00157 8.3e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
APOCAHHA_00158 3.5e-174 mpr 3.4.21.19 M Belongs to the peptidase S1B family
APOCAHHA_00160 4.5e-155 S Alpha/beta hydrolase family
APOCAHHA_00161 3.5e-94 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APOCAHHA_00162 3.5e-85 ybfM S SNARE associated Golgi protein
APOCAHHA_00163 9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
APOCAHHA_00164 2.8e-42 ybfN
APOCAHHA_00165 5.8e-247 S Erythromycin esterase
APOCAHHA_00166 4.8e-134 ybfP K Transcriptional regulator
APOCAHHA_00167 1.4e-189 yceA S Belongs to the UPF0176 family
APOCAHHA_00168 1.1e-210 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOCAHHA_00169 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOCAHHA_00170 1e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APOCAHHA_00171 1.1e-127 K UTRA
APOCAHHA_00173 5.1e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
APOCAHHA_00174 1.7e-257 mmuP E amino acid
APOCAHHA_00175 1.3e-176 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
APOCAHHA_00176 4.5e-253 agcS E Sodium alanine symporter
APOCAHHA_00177 1e-179 glsA 3.5.1.2 E Belongs to the glutaminase family
APOCAHHA_00178 2.3e-222 phoQ 2.7.13.3 T Histidine kinase
APOCAHHA_00179 2.3e-165 glnL T Regulator
APOCAHHA_00180 7.5e-169 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
APOCAHHA_00181 6.7e-268 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APOCAHHA_00182 7.2e-253 gudP G COG0477 Permeases of the major facilitator superfamily
APOCAHHA_00183 2.5e-261 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APOCAHHA_00184 1.8e-122 ycbG K FCD
APOCAHHA_00185 8.3e-290 garD 4.2.1.42, 4.2.1.7 G Altronate
APOCAHHA_00186 1e-161 ycbJ S Macrolide 2'-phosphotransferase
APOCAHHA_00187 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
APOCAHHA_00188 5.7e-148 eamA1 EG spore germination
APOCAHHA_00189 3.3e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_00190 1.3e-157 T PhoQ Sensor
APOCAHHA_00191 2.3e-157 ycbN V ABC transporter, ATP-binding protein
APOCAHHA_00192 3.2e-100 S ABC-2 family transporter protein
APOCAHHA_00193 3.1e-52 ycbP S Protein of unknown function (DUF2512)
APOCAHHA_00195 1.1e-77 sleB 3.5.1.28 M Cell wall
APOCAHHA_00196 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
APOCAHHA_00197 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APOCAHHA_00198 8.3e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APOCAHHA_00199 1.7e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APOCAHHA_00200 7.6e-192 ycbU E Selenocysteine lyase
APOCAHHA_00201 2.9e-228 lmrB EGP the major facilitator superfamily
APOCAHHA_00202 1e-99 yxaF K Transcriptional regulator
APOCAHHA_00203 2.6e-192 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
APOCAHHA_00204 8.4e-111 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
APOCAHHA_00205 8.7e-55 S RDD family
APOCAHHA_00206 1.3e-193 yccF K DNA-templated transcriptional preinitiation complex assembly
APOCAHHA_00207 1.2e-140 2.7.13.3 T GHKL domain
APOCAHHA_00208 1.8e-122 lytR_2 T LytTr DNA-binding domain
APOCAHHA_00209 1.7e-131 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
APOCAHHA_00210 1.7e-194 natB CP ABC-2 family transporter protein
APOCAHHA_00211 2.4e-167 yccK C Aldo keto reductase
APOCAHHA_00212 7.5e-181 ycdA S Domain of unknown function (DUF5105)
APOCAHHA_00213 2.1e-255 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_00214 1.3e-246 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_00215 2.7e-88 cwlK M D-alanyl-D-alanine carboxypeptidase
APOCAHHA_00216 9.1e-169 S response regulator aspartate phosphatase
APOCAHHA_00217 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
APOCAHHA_00218 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
APOCAHHA_00219 2.8e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
APOCAHHA_00220 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APOCAHHA_00221 6.7e-132 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APOCAHHA_00222 2.4e-181 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOCAHHA_00223 1.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
APOCAHHA_00224 8.2e-105 yceD T proteins involved in stress response, homologs of TerZ and
APOCAHHA_00225 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
APOCAHHA_00226 1.4e-136 terC P Protein of unknown function (DUF475)
APOCAHHA_00227 0.0 yceG S Putative component of 'biosynthetic module'
APOCAHHA_00228 1.3e-191 yceH P Belongs to the TelA family
APOCAHHA_00229 9.6e-217 naiP P Uncharacterised MFS-type transporter YbfB
APOCAHHA_00230 8.8e-199 yceJ EGP Uncharacterised MFS-type transporter YbfB
APOCAHHA_00231 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
APOCAHHA_00232 8.2e-227 proV 3.6.3.32 E glycine betaine
APOCAHHA_00233 5.5e-126 opuAB P glycine betaine
APOCAHHA_00234 2.5e-161 opuAC E glycine betaine
APOCAHHA_00235 5e-215 amhX S amidohydrolase
APOCAHHA_00236 1.8e-254 ycgA S Membrane
APOCAHHA_00237 4.4e-75 ycgB
APOCAHHA_00238 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
APOCAHHA_00239 4e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APOCAHHA_00240 4.1e-287 lctP C L-lactate permease
APOCAHHA_00241 2.8e-261 mdr EGP Major facilitator Superfamily
APOCAHHA_00242 1.1e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
APOCAHHA_00243 9.8e-112 ycgF E Lysine exporter protein LysE YggA
APOCAHHA_00244 2.1e-145 yqcI S YqcI/YcgG family
APOCAHHA_00245 8.1e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
APOCAHHA_00246 2.4e-112 ycgI S Domain of unknown function (DUF1989)
APOCAHHA_00247 3.2e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APOCAHHA_00248 1.4e-99 tmrB S AAA domain
APOCAHHA_00250 7.4e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APOCAHHA_00251 1.3e-139 yafE Q ubiE/COQ5 methyltransferase family
APOCAHHA_00252 1.3e-171 oxyR3 K LysR substrate binding domain
APOCAHHA_00253 2.2e-179 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
APOCAHHA_00254 1.6e-143 ycgL S Predicted nucleotidyltransferase
APOCAHHA_00255 3.7e-168 ycgM E Proline dehydrogenase
APOCAHHA_00256 2.8e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
APOCAHHA_00257 4.9e-252 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOCAHHA_00258 1.5e-225 ycgP QT COG2508 Regulator of polyketide synthase expression
APOCAHHA_00259 1.2e-144 ycgQ S membrane
APOCAHHA_00260 7.1e-140 ycgR S permeases
APOCAHHA_00261 1.2e-149 I alpha/beta hydrolase fold
APOCAHHA_00262 2.8e-185 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
APOCAHHA_00263 8.1e-263 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
APOCAHHA_00264 2.3e-56 nirD 1.7.1.15 P Nitrite reductase
APOCAHHA_00265 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APOCAHHA_00266 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOCAHHA_00267 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
APOCAHHA_00268 3.2e-144 nasA P COG2223 Nitrate nitrite transporter
APOCAHHA_00269 2.6e-65 nasA P COG2223 Nitrate nitrite transporter
APOCAHHA_00270 1.1e-164 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
APOCAHHA_00271 8.5e-69 yciB M ErfK YbiS YcfS YnhG
APOCAHHA_00272 2.5e-225 yciC S GTPases (G3E family)
APOCAHHA_00273 6e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
APOCAHHA_00274 1.2e-128 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
APOCAHHA_00276 1e-43 yckD S Protein of unknown function (DUF2680)
APOCAHHA_00277 4.9e-292 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APOCAHHA_00278 6.1e-67 nin S Competence protein J (ComJ)
APOCAHHA_00279 3e-67 nucA M Deoxyribonuclease NucA/NucB
APOCAHHA_00280 4e-139 tlpC 2.7.13.3 NT chemotaxis protein
APOCAHHA_00281 1.1e-90 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
APOCAHHA_00282 4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
APOCAHHA_00283 1.1e-59 hxlR K transcriptional
APOCAHHA_00284 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_00285 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_00286 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
APOCAHHA_00287 5.6e-135 srfAD Q thioesterase
APOCAHHA_00288 1.1e-220 EGP Major Facilitator Superfamily
APOCAHHA_00289 6e-81 S YcxB-like protein
APOCAHHA_00290 2e-153 ycxC EG EamA-like transporter family
APOCAHHA_00291 4.1e-245 ycxD K GntR family transcriptional regulator
APOCAHHA_00292 1.7e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
APOCAHHA_00293 5.3e-113 yczE S membrane
APOCAHHA_00294 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APOCAHHA_00295 8.1e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
APOCAHHA_00296 2.9e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
APOCAHHA_00297 1.9e-158 bsdA K LysR substrate binding domain
APOCAHHA_00298 9.2e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
APOCAHHA_00299 9.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
APOCAHHA_00300 1.5e-38 bsdD 4.1.1.61 S response to toxic substance
APOCAHHA_00301 3.4e-77 yclD
APOCAHHA_00302 3.8e-151 yclE 3.4.11.5 S Alpha beta hydrolase
APOCAHHA_00303 5.6e-267 dtpT E amino acid peptide transporter
APOCAHHA_00304 7.3e-282 yclG M Pectate lyase superfamily protein
APOCAHHA_00306 1.5e-276 gerKA EG Spore germination protein
APOCAHHA_00307 1.6e-219 gerKC S spore germination
APOCAHHA_00308 5.3e-193 gerKB F Spore germination protein
APOCAHHA_00309 1.9e-121 yclH P ABC transporter
APOCAHHA_00310 6.1e-197 yclI V ABC transporter (permease) YclI
APOCAHHA_00311 1.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_00312 6.8e-254 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
APOCAHHA_00313 4e-71 S aspartate phosphatase
APOCAHHA_00316 3.7e-249 lysC 2.7.2.4 E Belongs to the aspartokinase family
APOCAHHA_00317 7.7e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_00318 2.8e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_00319 1.7e-134 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
APOCAHHA_00320 2.1e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
APOCAHHA_00321 5e-249 ycnB EGP Major facilitator Superfamily
APOCAHHA_00322 2.3e-151 ycnC K Transcriptional regulator
APOCAHHA_00323 3.7e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
APOCAHHA_00324 5.8e-43 ycnE S Monooxygenase
APOCAHHA_00325 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
APOCAHHA_00326 3.6e-263 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOCAHHA_00327 7.2e-242 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOCAHHA_00328 1.2e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APOCAHHA_00329 2.3e-148 glcU U Glucose uptake
APOCAHHA_00330 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_00331 5.6e-96 ycnI S protein conserved in bacteria
APOCAHHA_00332 3e-298 ycnJ P protein, homolog of Cu resistance protein CopC
APOCAHHA_00333 1.8e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
APOCAHHA_00334 7.3e-56
APOCAHHA_00335 9.2e-55 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
APOCAHHA_00336 2.1e-159 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
APOCAHHA_00337 7.5e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
APOCAHHA_00338 2.9e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
APOCAHHA_00339 4.4e-197 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
APOCAHHA_00340 2e-92 sipT 3.4.21.89 U Belongs to the peptidase S26 family
APOCAHHA_00341 8.9e-102 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
APOCAHHA_00342 1.9e-65 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
APOCAHHA_00344 1.8e-133 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
APOCAHHA_00345 1.3e-137 ycsF S Belongs to the UPF0271 (lamB) family
APOCAHHA_00346 2e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
APOCAHHA_00347 2.9e-145 ycsI S Belongs to the D-glutamate cyclase family
APOCAHHA_00348 2.8e-131 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
APOCAHHA_00349 1.2e-180 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
APOCAHHA_00350 1.7e-131 kipR K Transcriptional regulator
APOCAHHA_00351 5.8e-112 ycsK E anatomical structure formation involved in morphogenesis
APOCAHHA_00353 2.9e-47 yczJ S biosynthesis
APOCAHHA_00354 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
APOCAHHA_00355 7.8e-171 ydhF S Oxidoreductase
APOCAHHA_00356 0.0 mtlR K transcriptional regulator, MtlR
APOCAHHA_00357 1e-287 ydaB IQ acyl-CoA ligase
APOCAHHA_00358 7.4e-93 ydaC Q Methyltransferase domain
APOCAHHA_00359 8.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_00360 1.5e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
APOCAHHA_00361 1e-96 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APOCAHHA_00362 3.4e-76 ydaG 1.4.3.5 S general stress protein
APOCAHHA_00363 2.1e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
APOCAHHA_00364 4.3e-46 ydzA EGP Major facilitator Superfamily
APOCAHHA_00365 2.5e-74 lrpC K Transcriptional regulator
APOCAHHA_00366 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APOCAHHA_00367 8.7e-201 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
APOCAHHA_00368 5.7e-147 ydaK T Diguanylate cyclase, GGDEF domain
APOCAHHA_00369 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
APOCAHHA_00370 2.2e-232 ydaM M Glycosyl transferase family group 2
APOCAHHA_00371 0.0 ydaN S Bacterial cellulose synthase subunit
APOCAHHA_00372 0.0 ydaO E amino acid
APOCAHHA_00373 3.3e-67 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
APOCAHHA_00374 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
APOCAHHA_00376 3.3e-37
APOCAHHA_00377 3.9e-224 mntH P H( )-stimulated, divalent metal cation uptake system
APOCAHHA_00379 3.4e-58 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
APOCAHHA_00380 6.7e-145 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
APOCAHHA_00382 6.8e-56 ydbB G Cupin domain
APOCAHHA_00383 1.3e-55 ydbC S Domain of unknown function (DUF4937
APOCAHHA_00384 7.9e-154 ydbD P Catalase
APOCAHHA_00385 6.3e-196 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
APOCAHHA_00386 9.3e-292 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APOCAHHA_00387 5.2e-119 dctR T COG4565 Response regulator of citrate malate metabolism
APOCAHHA_00388 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOCAHHA_00389 6.5e-177 ydbI S AI-2E family transporter
APOCAHHA_00390 6.6e-205 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOCAHHA_00391 3.8e-165 ydbJ V ABC transporter, ATP-binding protein
APOCAHHA_00392 3e-123 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APOCAHHA_00393 2.7e-52 ydbL
APOCAHHA_00394 5e-215 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
APOCAHHA_00395 1.1e-18 S Fur-regulated basic protein B
APOCAHHA_00396 2.2e-07 S Fur-regulated basic protein A
APOCAHHA_00397 5.8e-147 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APOCAHHA_00398 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APOCAHHA_00399 2.1e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
APOCAHHA_00400 4.2e-251 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APOCAHHA_00401 1.7e-247 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APOCAHHA_00402 2.8e-82 ydbS S Bacterial PH domain
APOCAHHA_00403 3.4e-256 ydbT S Membrane
APOCAHHA_00404 1.9e-104 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
APOCAHHA_00405 1.2e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APOCAHHA_00406 6.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
APOCAHHA_00407 1.5e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APOCAHHA_00408 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
APOCAHHA_00409 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
APOCAHHA_00410 8.2e-143 rsbR T Positive regulator of sigma-B
APOCAHHA_00411 6.8e-57 rsbS T antagonist
APOCAHHA_00412 6.5e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
APOCAHHA_00413 3e-187 rsbU 3.1.3.3 KT phosphatase
APOCAHHA_00414 6.6e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
APOCAHHA_00415 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
APOCAHHA_00416 5.8e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOCAHHA_00417 7.6e-106 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
APOCAHHA_00418 2.9e-14 J glyoxalase III activity
APOCAHHA_00419 1.6e-81 ydcG S EVE domain
APOCAHHA_00420 2.3e-75 ydcH K helix_turn_helix multiple antibiotic resistance protein
APOCAHHA_00421 0.0 yhgF K COG2183 Transcriptional accessory protein
APOCAHHA_00422 8.9e-83 ydcK S Belongs to the SprT family
APOCAHHA_00430 7.4e-24 rimJ2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APOCAHHA_00431 1.2e-28 rimJ2 J Acetyltransferase (GNAT) domain
APOCAHHA_00432 2.3e-42
APOCAHHA_00434 1.3e-49 S SMI1-KNR4 cell-wall
APOCAHHA_00435 2.8e-204 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APOCAHHA_00436 3.5e-42 S Putative amidase domain
APOCAHHA_00437 9.6e-11
APOCAHHA_00438 6.6e-23 yddI
APOCAHHA_00439 7.6e-94 ywrO S Flavodoxin-like fold
APOCAHHA_00440 8.7e-166 ydjN U Involved in the tonB-independent uptake of proteins
APOCAHHA_00441 1.6e-119 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
APOCAHHA_00442 5.2e-146 yeaN P transporter
APOCAHHA_00443 9.9e-134 cynR K Transcriptional regulator
APOCAHHA_00444 2.7e-85 S protein conserved in bacteria
APOCAHHA_00445 2.2e-39 MA20_06410 E threonine efflux protein
APOCAHHA_00446 0.0 M Domain of unknown function DUF11
APOCAHHA_00447 1e-78 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
APOCAHHA_00448 1.1e-29 cspL K Cold shock
APOCAHHA_00449 6.5e-138 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APOCAHHA_00450 4.5e-155 rhaS5 K AraC-like ligand binding domain
APOCAHHA_00451 2.9e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APOCAHHA_00452 1.9e-150 ydeE K AraC family transcriptional regulator
APOCAHHA_00453 4.9e-257 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOCAHHA_00454 1.3e-206 ydeG EGP Major facilitator superfamily
APOCAHHA_00455 3.8e-39 ydeH
APOCAHHA_00456 1.9e-96 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
APOCAHHA_00457 4.8e-85
APOCAHHA_00458 3.9e-151 ydeK EG -transporter
APOCAHHA_00459 2.1e-263 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOCAHHA_00460 1.8e-72 maoC I N-terminal half of MaoC dehydratase
APOCAHHA_00461 1.8e-104 ydeN S Serine hydrolase
APOCAHHA_00462 2.4e-53 K HxlR-like helix-turn-helix
APOCAHHA_00463 1.9e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
APOCAHHA_00464 3.3e-177 ydeR EGP Major facilitator Superfamily
APOCAHHA_00465 3.5e-100 ydeS K Transcriptional regulator
APOCAHHA_00466 2.8e-222 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APOCAHHA_00467 1.5e-122 ydfB J GNAT acetyltransferase
APOCAHHA_00468 2.8e-147 ydfC EG EamA-like transporter family
APOCAHHA_00469 9.6e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOCAHHA_00470 1.8e-113 ydfE S Flavin reductase like domain
APOCAHHA_00471 4e-119 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
APOCAHHA_00472 1.1e-77 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APOCAHHA_00474 4.4e-174 ydfH 2.7.13.3 T Histidine kinase
APOCAHHA_00475 1.1e-105 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_00476 0.0 ydfJ S drug exporters of the RND superfamily
APOCAHHA_00477 4.3e-169 S Alpha/beta hydrolase family
APOCAHHA_00478 3.1e-203 K Transcriptional regulator
APOCAHHA_00479 3.8e-120 azlC E AzlC protein
APOCAHHA_00480 1.5e-47 azlD E Branched-chain amino acid transport protein (AzlD)
APOCAHHA_00481 2.7e-212 brnQ E Component of the transport system for branched-chain amino acids
APOCAHHA_00482 1.8e-12 rok K Repressor of ComK
APOCAHHA_00483 7.9e-115 S Protein of unknown function (DUF554)
APOCAHHA_00484 1.8e-142 K Bacterial transcription activator, effector binding domain
APOCAHHA_00485 4.5e-11 S response regulator aspartate phosphatase
APOCAHHA_00486 7e-13
APOCAHHA_00488 2.9e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APOCAHHA_00489 1.7e-108 ydfN C nitroreductase
APOCAHHA_00490 3.6e-179 ydfO E COG0346 Lactoylglutathione lyase and related lyases
APOCAHHA_00491 4.4e-62 mhqP S DoxX
APOCAHHA_00492 3.2e-53 traF CO Thioredoxin
APOCAHHA_00493 7.9e-14 ydgA S Spore germination protein gerPA/gerPF
APOCAHHA_00494 1.4e-20
APOCAHHA_00496 1.2e-95 ydfR S Protein of unknown function (DUF421)
APOCAHHA_00497 1.1e-119 ydfS S Protein of unknown function (DUF421)
APOCAHHA_00498 1.8e-69 cotP O Belongs to the small heat shock protein (HSP20) family
APOCAHHA_00499 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
APOCAHHA_00500 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
APOCAHHA_00501 1.5e-93 K Bacterial regulatory proteins, tetR family
APOCAHHA_00502 2.9e-46 S DoxX-like family
APOCAHHA_00503 3.7e-79 yycN 2.3.1.128 K Acetyltransferase
APOCAHHA_00504 2.2e-296 expZ S ABC transporter
APOCAHHA_00505 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
APOCAHHA_00506 1.9e-84 dinB S DinB family
APOCAHHA_00507 2.8e-76 K helix_turn_helix multiple antibiotic resistance protein
APOCAHHA_00508 0.0 ydgH S drug exporters of the RND superfamily
APOCAHHA_00509 1.5e-112 drgA C nitroreductase
APOCAHHA_00510 4.1e-69 ydgJ K Winged helix DNA-binding domain
APOCAHHA_00511 1.5e-206 tcaB EGP Major facilitator Superfamily
APOCAHHA_00512 7.9e-121 ydhB S membrane transporter protein
APOCAHHA_00513 3.7e-101 ydhC K FCD
APOCAHHA_00514 3.8e-232 ydhD M Glycosyl hydrolase
APOCAHHA_00515 4.4e-222 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APOCAHHA_00516 1.4e-117
APOCAHHA_00517 6.4e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
APOCAHHA_00518 1.5e-64 frataxin S Domain of unknown function (DU1801)
APOCAHHA_00520 7.5e-80 K Acetyltransferase (GNAT) domain
APOCAHHA_00521 1.4e-170 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
APOCAHHA_00522 3.4e-92 ydhK M Protein of unknown function (DUF1541)
APOCAHHA_00523 7.9e-200 pbuE EGP Major facilitator Superfamily
APOCAHHA_00524 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
APOCAHHA_00525 2.5e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
APOCAHHA_00526 3.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APOCAHHA_00527 8.7e-278 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APOCAHHA_00528 1.9e-132 ydhQ K UTRA
APOCAHHA_00529 1.4e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
APOCAHHA_00530 4.3e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
APOCAHHA_00531 3.9e-209 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
APOCAHHA_00534 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_00535 7.8e-08
APOCAHHA_00537 1.5e-167 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
APOCAHHA_00538 4.2e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
APOCAHHA_00539 5.7e-121 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
APOCAHHA_00540 8.1e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
APOCAHHA_00541 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APOCAHHA_00542 0.0 ydiF S ABC transporter
APOCAHHA_00543 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
APOCAHHA_00544 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APOCAHHA_00545 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APOCAHHA_00546 9.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APOCAHHA_00547 2.9e-27 ydiK S Domain of unknown function (DUF4305)
APOCAHHA_00548 3.6e-126 ydiL S CAAX protease self-immunity
APOCAHHA_00549 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APOCAHHA_00550 4.1e-279 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APOCAHHA_00551 6e-153 ydjC S Abhydrolase domain containing 18
APOCAHHA_00552 0.0 K NB-ARC domain
APOCAHHA_00553 4.8e-196 gutB 1.1.1.14 E Dehydrogenase
APOCAHHA_00554 5.3e-251 gutA G MFS/sugar transport protein
APOCAHHA_00555 5e-168 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
APOCAHHA_00556 1.6e-112 pspA KT Phage shock protein A
APOCAHHA_00557 1.6e-175 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APOCAHHA_00558 8.6e-112 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
APOCAHHA_00559 1.3e-147 ydjI S virion core protein (lumpy skin disease virus)
APOCAHHA_00560 4.8e-193 S Ion transport 2 domain protein
APOCAHHA_00561 2.1e-255 iolT EGP Major facilitator Superfamily
APOCAHHA_00562 2e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
APOCAHHA_00563 4.5e-64 ydjM M Lytic transglycolase
APOCAHHA_00564 4.1e-147 ydjN U Involved in the tonB-independent uptake of proteins
APOCAHHA_00565 1.4e-34 ydjO S Cold-inducible protein YdjO
APOCAHHA_00566 5.3e-150 ydjP I Alpha/beta hydrolase family
APOCAHHA_00567 8.5e-311 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
APOCAHHA_00568 4.5e-250 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
APOCAHHA_00569 2.1e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APOCAHHA_00570 2.6e-172 yeaC S COG0714 MoxR-like ATPases
APOCAHHA_00571 1.6e-211 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
APOCAHHA_00572 0.0 yebA E COG1305 Transglutaminase-like enzymes
APOCAHHA_00573 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
APOCAHHA_00574 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_00575 1.5e-243 S Domain of unknown function (DUF4179)
APOCAHHA_00576 1.5e-210 pbuG S permease
APOCAHHA_00577 1e-113 yebC M Membrane
APOCAHHA_00579 4e-93 yebE S UPF0316 protein
APOCAHHA_00580 2.3e-27 yebG S NETI protein
APOCAHHA_00581 4.8e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APOCAHHA_00582 8.3e-210 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APOCAHHA_00583 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APOCAHHA_00584 9.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
APOCAHHA_00585 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOCAHHA_00586 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOCAHHA_00587 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOCAHHA_00588 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APOCAHHA_00589 3.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
APOCAHHA_00590 4.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APOCAHHA_00591 8.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
APOCAHHA_00592 4.2e-231 purD 6.3.4.13 F Belongs to the GARS family
APOCAHHA_00593 9.6e-71 K helix_turn_helix ASNC type
APOCAHHA_00594 5.9e-225 yjeH E Amino acid permease
APOCAHHA_00595 3.7e-29 S Protein of unknown function (DUF2892)
APOCAHHA_00596 0.0 yerA 3.5.4.2 F adenine deaminase
APOCAHHA_00597 2.8e-185 yerB S Protein of unknown function (DUF3048) C-terminal domain
APOCAHHA_00598 4.8e-51 yerC S protein conserved in bacteria
APOCAHHA_00599 1.6e-299 yerD 1.4.7.1 E Belongs to the glutamate synthase family
APOCAHHA_00600 8.7e-122 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
APOCAHHA_00601 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
APOCAHHA_00602 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APOCAHHA_00603 4.6e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
APOCAHHA_00604 8.3e-120 yfmI1 G Major Facilitator Superfamily
APOCAHHA_00605 0.0 Q Condensation domain
APOCAHHA_00606 4.5e-115 flp V Beta-lactamase
APOCAHHA_00607 7.4e-74
APOCAHHA_00608 2.4e-87 bacT Q Thioesterase domain
APOCAHHA_00609 5.9e-120 ditN 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
APOCAHHA_00610 9.2e-147 Q Haloacid dehalogenase-like hydrolase
APOCAHHA_00611 1.3e-33 IQ Phosphopantetheine attachment site
APOCAHHA_00612 7.6e-171 C Acyl-CoA dehydrogenase, N-terminal domain
APOCAHHA_00613 0.0 IQ polyketide synthase
APOCAHHA_00614 7.5e-238 6.1.1.13 Q Condensation domain
APOCAHHA_00615 0.0 Q Polyketide synthase of type I
APOCAHHA_00616 3.1e-222 Q Polyketide synthase of type I
APOCAHHA_00617 0.0 Q Polyketide synthase of type I
APOCAHHA_00618 0.0 Q Polyketide synthase of type I
APOCAHHA_00619 1e-171 yerI S homoserine kinase type II (protein kinase fold)
APOCAHHA_00620 3.2e-151 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
APOCAHHA_00622 3.9e-122 sapB S MgtC SapB transporter
APOCAHHA_00623 3.2e-246 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOCAHHA_00624 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APOCAHHA_00625 1e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APOCAHHA_00626 6.8e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APOCAHHA_00627 2.3e-140 yerO K Transcriptional regulator
APOCAHHA_00628 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APOCAHHA_00629 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APOCAHHA_00630 1.4e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APOCAHHA_00632 1.8e-100 S response regulator aspartate phosphatase
APOCAHHA_00634 7.1e-72 S Protein of unknown function, DUF600
APOCAHHA_00635 6.6e-84 S Protein of unknown function, DUF600
APOCAHHA_00636 0.0 L nucleic acid phosphodiester bond hydrolysis
APOCAHHA_00638 4.3e-100 L endonuclease activity
APOCAHHA_00639 2.6e-49
APOCAHHA_00640 4.6e-62 S Protein of unknown function (DUF421)
APOCAHHA_00641 1.4e-204 S Tetratricopeptide repeat
APOCAHHA_00643 2.7e-126 yeeN K transcriptional regulatory protein
APOCAHHA_00645 1.7e-97 dhaR3 K Transcriptional regulator
APOCAHHA_00646 4.8e-81 yesE S SnoaL-like domain
APOCAHHA_00647 1e-140 yesF GM NAD(P)H-binding
APOCAHHA_00648 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
APOCAHHA_00649 4.3e-45 cotJB S CotJB protein
APOCAHHA_00650 3.4e-103 cotJC P Spore Coat
APOCAHHA_00651 1.9e-100 yesJ K Acetyltransferase (GNAT) family
APOCAHHA_00653 6.1e-98 yesL S Protein of unknown function, DUF624
APOCAHHA_00654 0.0 yesM 2.7.13.3 T Histidine kinase
APOCAHHA_00655 4.6e-197 yesN K helix_turn_helix, arabinose operon control protein
APOCAHHA_00656 1.2e-244 yesO G Bacterial extracellular solute-binding protein
APOCAHHA_00657 2.6e-169 yesP G Binding-protein-dependent transport system inner membrane component
APOCAHHA_00658 3.5e-163 yesQ P Binding-protein-dependent transport system inner membrane component
APOCAHHA_00659 7.3e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
APOCAHHA_00660 0.0 yesS K Transcriptional regulator
APOCAHHA_00661 3.7e-128 E GDSL-like Lipase/Acylhydrolase
APOCAHHA_00662 1.4e-124 yesU S Domain of unknown function (DUF1961)
APOCAHHA_00663 2.6e-112 yesV S Protein of unknown function, DUF624
APOCAHHA_00664 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
APOCAHHA_00665 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
APOCAHHA_00666 6.3e-122 yesY E GDSL-like Lipase/Acylhydrolase
APOCAHHA_00667 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
APOCAHHA_00668 0.0 yetA
APOCAHHA_00669 3.3e-283 lplA G Bacterial extracellular solute-binding protein
APOCAHHA_00670 3.1e-69 lplB G COG4209 ABC-type polysaccharide transport system, permease component
APOCAHHA_00671 1.4e-96 lplB G COG4209 ABC-type polysaccharide transport system, permease component
APOCAHHA_00672 1.2e-160 lplC G Binding-protein-dependent transport system inner membrane component
APOCAHHA_00673 5.4e-237 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
APOCAHHA_00674 6.3e-120 yetF S membrane
APOCAHHA_00675 2.8e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
APOCAHHA_00676 1.7e-63 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOCAHHA_00677 5.4e-33
APOCAHHA_00678 4.9e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APOCAHHA_00679 5.8e-19 yezD S Uncharacterized small protein (DUF2292)
APOCAHHA_00680 3.4e-104 yetJ S Belongs to the BI1 family
APOCAHHA_00681 6.8e-13 yetM CH FAD binding domain
APOCAHHA_00682 5.2e-198 yetN S Protein of unknown function (DUF3900)
APOCAHHA_00683 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
APOCAHHA_00684 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APOCAHHA_00685 6.7e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
APOCAHHA_00686 3.2e-172 yfnG 4.2.1.45 M dehydratase
APOCAHHA_00687 7.4e-177 yfnF M Nucleotide-diphospho-sugar transferase
APOCAHHA_00688 3.3e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
APOCAHHA_00689 3.1e-186 yfnD M Nucleotide-diphospho-sugar transferase
APOCAHHA_00690 6.6e-205 fsr P COG0477 Permeases of the major facilitator superfamily
APOCAHHA_00691 7.8e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
APOCAHHA_00692 5.4e-240 yfnA E amino acid
APOCAHHA_00693 2.6e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APOCAHHA_00694 1.6e-112 yfmS NT chemotaxis protein
APOCAHHA_00695 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APOCAHHA_00696 2.7e-71 yfmQ S Uncharacterised protein from bacillus cereus group
APOCAHHA_00697 9.9e-68 yfmP K transcriptional
APOCAHHA_00698 3.6e-208 yfmO EGP Major facilitator Superfamily
APOCAHHA_00699 2.7e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APOCAHHA_00700 1.9e-198 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
APOCAHHA_00701 8e-76 yfmK 2.3.1.128 K acetyltransferase
APOCAHHA_00702 7.4e-186 yfmJ S N-terminal domain of oxidoreductase
APOCAHHA_00703 4.4e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
APOCAHHA_00704 4e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_00705 1.4e-168 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_00706 6.3e-155 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
APOCAHHA_00707 4.5e-24 S Protein of unknown function (DUF3212)
APOCAHHA_00708 1.4e-56 yflT S Heat induced stress protein YflT
APOCAHHA_00709 1.2e-238 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
APOCAHHA_00710 1.6e-234 yflS P Sodium:sulfate symporter transmembrane region
APOCAHHA_00711 1e-274 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APOCAHHA_00712 7.8e-115 citT T response regulator
APOCAHHA_00713 1.4e-173 yflP S Tripartite tricarboxylate transporter family receptor
APOCAHHA_00714 5.5e-226 citM C Citrate transporter
APOCAHHA_00715 3.4e-146 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
APOCAHHA_00716 6.9e-214 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
APOCAHHA_00717 2.1e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
APOCAHHA_00718 3.2e-113 yflK S protein conserved in bacteria
APOCAHHA_00719 8.9e-18 yflJ S Protein of unknown function (DUF2639)
APOCAHHA_00720 3.5e-18 yflI
APOCAHHA_00721 1.1e-47 yflH S Protein of unknown function (DUF3243)
APOCAHHA_00722 4.2e-138 map 3.4.11.18 E Methionine aminopeptidase
APOCAHHA_00723 2.2e-249 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
APOCAHHA_00724 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APOCAHHA_00725 3.3e-65 yhdN S Domain of unknown function (DUF1992)
APOCAHHA_00726 3.6e-255 agcS_1 E Sodium alanine symporter
APOCAHHA_00728 2.6e-253 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOCAHHA_00729 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
APOCAHHA_00730 4.8e-131 treR K transcriptional
APOCAHHA_00731 1.2e-123 yfkO C nitroreductase
APOCAHHA_00732 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
APOCAHHA_00733 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
APOCAHHA_00734 3.9e-157 ydiM EGP Major facilitator Superfamily
APOCAHHA_00735 1.7e-25 ydiM EGP Major facilitator Superfamily
APOCAHHA_00736 1.8e-28 yfkK S Belongs to the UPF0435 family
APOCAHHA_00737 5.1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APOCAHHA_00738 4.1e-50 yfkI S gas vesicle protein
APOCAHHA_00739 5e-120 yihY S Belongs to the UPF0761 family
APOCAHHA_00740 5.6e-12 yihY S Belongs to the UPF0761 family
APOCAHHA_00741 5e-08
APOCAHHA_00742 1.2e-216 ycaD EGP COG0477 Permeases of the major facilitator superfamily
APOCAHHA_00743 7.4e-181 cax P COG0387 Ca2 H antiporter
APOCAHHA_00744 1.9e-144 yfkD S YfkD-like protein
APOCAHHA_00745 1.1e-145 yfkC M Mechanosensitive ion channel
APOCAHHA_00746 3.5e-221 yfkA S YfkB-like domain
APOCAHHA_00747 1.1e-26 yfjT
APOCAHHA_00748 6.4e-153 pdaA G deacetylase
APOCAHHA_00749 3.5e-144 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
APOCAHHA_00750 3e-181 corA P Mediates influx of magnesium ions
APOCAHHA_00751 1.7e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APOCAHHA_00752 5.8e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APOCAHHA_00753 7.4e-43 S YfzA-like protein
APOCAHHA_00754 7.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APOCAHHA_00755 7.1e-80 yfjM S Psort location Cytoplasmic, score
APOCAHHA_00756 1.5e-28 yfjL
APOCAHHA_00757 1.1e-189 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APOCAHHA_00758 1e-187 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APOCAHHA_00759 1.1e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APOCAHHA_00760 2.9e-249 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APOCAHHA_00761 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
APOCAHHA_00762 3.7e-24 sspH S Belongs to the SspH family
APOCAHHA_00763 9.7e-55 yfjF S UPF0060 membrane protein
APOCAHHA_00764 2.5e-87 S Family of unknown function (DUF5381)
APOCAHHA_00765 1.1e-122 yfjC
APOCAHHA_00766 7.3e-172 yfjB
APOCAHHA_00767 5.7e-44 yfjA S Belongs to the WXG100 family
APOCAHHA_00768 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APOCAHHA_00769 1e-139 glvR K Helix-turn-helix domain, rpiR family
APOCAHHA_00770 6.3e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOCAHHA_00771 1.8e-301 yfiB3 V ABC transporter
APOCAHHA_00772 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
APOCAHHA_00773 5.4e-63 mhqP S DoxX
APOCAHHA_00774 3.7e-154 yfiE 1.13.11.2 S glyoxalase
APOCAHHA_00776 2.3e-204 yxjM T Histidine kinase
APOCAHHA_00777 6.7e-111 KT LuxR family transcriptional regulator
APOCAHHA_00778 3.9e-165 V ABC transporter, ATP-binding protein
APOCAHHA_00779 3.2e-196 V ABC-2 family transporter protein
APOCAHHA_00780 1.1e-198 V COG0842 ABC-type multidrug transport system, permease component
APOCAHHA_00781 6.1e-94 padR K transcriptional
APOCAHHA_00782 7.9e-194 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
APOCAHHA_00783 1.1e-107 yfiR K Transcriptional regulator
APOCAHHA_00784 6.5e-200 yfiS EGP Major facilitator Superfamily
APOCAHHA_00785 7.1e-95 yfiT S Belongs to the metal hydrolase YfiT family
APOCAHHA_00786 1.5e-278 yfiU EGP Major facilitator Superfamily
APOCAHHA_00787 1.4e-78 yfiV K transcriptional
APOCAHHA_00788 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APOCAHHA_00789 1.2e-172 yfiY P ABC transporter substrate-binding protein
APOCAHHA_00790 1.3e-171 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_00791 3.4e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_00792 3.2e-161 yfhB 5.3.3.17 S PhzF family
APOCAHHA_00793 3.1e-104 yfhC C nitroreductase
APOCAHHA_00794 3.1e-24 yfhD S YfhD-like protein
APOCAHHA_00796 2e-166 yfhF S nucleoside-diphosphate sugar epimerase
APOCAHHA_00797 7.9e-135 recX 2.4.1.337 GT4 S Modulates RecA activity
APOCAHHA_00798 8.2e-51 yfhH S Protein of unknown function (DUF1811)
APOCAHHA_00799 2.4e-204 yfhI EGP Major facilitator Superfamily
APOCAHHA_00800 6.2e-20 sspK S reproduction
APOCAHHA_00801 8.3e-44 yfhJ S WVELL protein
APOCAHHA_00802 3.1e-87 batE T Bacterial SH3 domain homologues
APOCAHHA_00803 7.4e-42 yfhL S SdpI/YhfL protein family
APOCAHHA_00804 7.5e-163 yfhM S Alpha beta hydrolase
APOCAHHA_00805 4e-184 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APOCAHHA_00806 1.9e-139 yfhO S Bacterial membrane protein YfhO
APOCAHHA_00807 7.1e-306 yfhO S Bacterial membrane protein YfhO
APOCAHHA_00808 3.9e-184 yfhP S membrane-bound metal-dependent
APOCAHHA_00809 8.5e-211 mutY L A G-specific
APOCAHHA_00810 2.6e-35 yfhS
APOCAHHA_00811 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_00812 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
APOCAHHA_00813 1.5e-37 ygaB S YgaB-like protein
APOCAHHA_00814 1.3e-104 ygaC J Belongs to the UPF0374 family
APOCAHHA_00815 2.7e-297 ygaD V ABC transporter
APOCAHHA_00816 4.7e-178 ygaE S Membrane
APOCAHHA_00817 3.9e-240 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
APOCAHHA_00818 9e-86 bcp 1.11.1.15 O Peroxiredoxin
APOCAHHA_00819 4e-80 perR P Belongs to the Fur family
APOCAHHA_00820 1.2e-55 ygzB S UPF0295 protein
APOCAHHA_00821 4.1e-164 ygxA S Nucleotidyltransferase-like
APOCAHHA_00822 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_00827 7.8e-08
APOCAHHA_00835 2e-08
APOCAHHA_00839 1.3e-46 nusG K Participates in transcription elongation, termination and antitermination
APOCAHHA_00840 1.6e-108 2.3.1.252 Q Polyketide synthase modules and related proteins
APOCAHHA_00841 1.9e-128 V Polysaccharide biosynthesis C-terminal domain
APOCAHHA_00842 3.3e-81 Q Methionine biosynthesis protein MetW
APOCAHHA_00843 1.3e-68 sfp3 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
APOCAHHA_00844 0.0 fabD 1.13.12.16, 2.3.1.39 I Acyl transferase domain
APOCAHHA_00845 1.5e-26 acpK IQ Phosphopantetheine attachment site
APOCAHHA_00846 1.2e-86 pksB 3.1.2.6 S Polyketide biosynthesis
APOCAHHA_00847 6.2e-95 I Alpha/beta hydrolase family
APOCAHHA_00848 5.7e-78 pksR Q Beta-ketoacyl synthase
APOCAHHA_00849 0.0 pksR Q Beta-ketoacyl synthase
APOCAHHA_00850 6.5e-256 pksR Q Polyketide synthase modules and related proteins
APOCAHHA_00851 0.0 pfaA Q Polyketide synthase modules and related proteins
APOCAHHA_00852 0.0 pksN Q Non-ribosomal peptide synthetase modules and related proteins
APOCAHHA_00853 1.2e-301 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
APOCAHHA_00854 1.8e-15 pksJ Q SMART Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase, phosphopantetheine-binding protein
APOCAHHA_00855 0.0 pksR Q Beta-ketoacyl synthase
APOCAHHA_00856 1.7e-160 pksF 2.3.1.179, 2.3.1.41 IQ Beta-ketoacyl synthase, C-terminal domain
APOCAHHA_00857 7e-218 pksG 2.3.3.10 I synthase
APOCAHHA_00858 5e-110 pksH 4.2.1.18 I Enoyl-CoA hydratase/isomerase
APOCAHHA_00859 4.3e-122 pksI I Belongs to the enoyl-CoA hydratase isomerase family
APOCAHHA_00860 1.3e-233 pks13 I Belongs to the enoyl-CoA hydratase isomerase family
APOCAHHA_00861 7.4e-99 4.2.1.44, 5.1.3.22 L Xylose isomerase-like TIM barrel
APOCAHHA_00862 1.6e-110 CG TIGRFAM glycosyltransferase, MGT family
APOCAHHA_00864 6.2e-63
APOCAHHA_00865 8e-210
APOCAHHA_00866 3.1e-174 V Multidrug transporter MatE
APOCAHHA_00867 9.7e-120 Q O-methyltransferase
APOCAHHA_00868 9.8e-138 spo0M S COG4326 Sporulation control protein
APOCAHHA_00869 7.5e-26
APOCAHHA_00870 1.9e-21 yraF M sporulation resulting in formation of a cellular spore
APOCAHHA_00871 1.5e-121 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
APOCAHHA_00872 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
APOCAHHA_00873 5e-254 ygaK C Berberine and berberine like
APOCAHHA_00875 1.5e-288 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
APOCAHHA_00876 9.7e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
APOCAHHA_00877 2.6e-167 ssuA M Sulfonate ABC transporter
APOCAHHA_00878 1.8e-142 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APOCAHHA_00879 1.9e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
APOCAHHA_00881 3.3e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APOCAHHA_00882 1.4e-73 ygaO
APOCAHHA_00883 4.4e-29 K Transcriptional regulator
APOCAHHA_00885 1.7e-108 yhzB S B3/4 domain
APOCAHHA_00886 4e-220 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APOCAHHA_00887 9.4e-172 yhbB S Putative amidase domain
APOCAHHA_00888 1.3e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APOCAHHA_00889 5.8e-104 yhbD K Protein of unknown function (DUF4004)
APOCAHHA_00890 2.2e-59 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
APOCAHHA_00891 1.8e-61 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
APOCAHHA_00892 0.0 prkA T Ser protein kinase
APOCAHHA_00893 3.6e-224 yhbH S Belongs to the UPF0229 family
APOCAHHA_00894 2.2e-76 yhbI K DNA-binding transcription factor activity
APOCAHHA_00895 1.2e-96 yhbJ V COG1566 Multidrug resistance efflux pump
APOCAHHA_00896 5.8e-270 yhcA EGP Major facilitator Superfamily
APOCAHHA_00897 8.8e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
APOCAHHA_00898 5.4e-33 yhcC
APOCAHHA_00899 6.6e-54
APOCAHHA_00900 3.6e-58 yhcF K Transcriptional regulator
APOCAHHA_00901 6.6e-117 yhcG V ABC transporter, ATP-binding protein
APOCAHHA_00902 8.8e-162 yhcH V ABC transporter, ATP-binding protein
APOCAHHA_00903 2.9e-160 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APOCAHHA_00904 1e-30 cspB K Cold-shock protein
APOCAHHA_00905 3.2e-147 metQ M Belongs to the nlpA lipoprotein family
APOCAHHA_00906 1.8e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
APOCAHHA_00907 6.1e-215 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOCAHHA_00908 7.8e-76 S Protein of unknown function (DUF2812)
APOCAHHA_00909 3.1e-50 K Transcriptional regulator PadR-like family
APOCAHHA_00910 4.6e-39 yhcM
APOCAHHA_00911 1.1e-64 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APOCAHHA_00912 5.1e-130 yhcP
APOCAHHA_00913 1.2e-96 yhcQ M Spore coat protein
APOCAHHA_00914 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
APOCAHHA_00915 5.3e-99 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
APOCAHHA_00916 3.4e-158 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APOCAHHA_00917 3e-66 yhcU S Family of unknown function (DUF5365)
APOCAHHA_00918 7.7e-11 yhcV S COG0517 FOG CBS domain
APOCAHHA_00919 9.7e-43 yhcV S COG0517 FOG CBS domain
APOCAHHA_00920 3.9e-119 yhcW 5.4.2.6 S hydrolase
APOCAHHA_00921 1.3e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APOCAHHA_00922 1.3e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOCAHHA_00923 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
APOCAHHA_00924 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
APOCAHHA_00925 3.9e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APOCAHHA_00926 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
APOCAHHA_00927 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
APOCAHHA_00928 8.8e-204 yhcY 2.7.13.3 T Histidine kinase
APOCAHHA_00929 5.7e-107 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_00930 2.3e-82 azr 1.7.1.6 S NADPH-dependent FMN reductase
APOCAHHA_00931 2.8e-38 yhdB S YhdB-like protein
APOCAHHA_00932 1.8e-53 yhdC S Protein of unknown function (DUF3889)
APOCAHHA_00933 1.3e-178 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APOCAHHA_00934 1.8e-75 nsrR K Transcriptional regulator
APOCAHHA_00935 1.1e-233 ygxB M Conserved TM helix
APOCAHHA_00936 5.9e-274 ycgB S Stage V sporulation protein R
APOCAHHA_00937 2.6e-250 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
APOCAHHA_00938 1.2e-135 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APOCAHHA_00939 3.9e-128 citR K Transcriptional regulator
APOCAHHA_00940 3.2e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
APOCAHHA_00941 2.1e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_00942 3.4e-250 yhdG E amino acid
APOCAHHA_00943 4e-235 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APOCAHHA_00944 3.3e-253 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOCAHHA_00945 4.1e-69 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOCAHHA_00946 8.1e-45 yhdK S Sigma-M inhibitor protein
APOCAHHA_00947 4.7e-199 yhdL S Sigma factor regulator N-terminal
APOCAHHA_00948 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_00949 5e-187 yhdN C Aldo keto reductase
APOCAHHA_00950 8.7e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APOCAHHA_00951 2.2e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
APOCAHHA_00952 1.3e-72 cueR K transcriptional
APOCAHHA_00953 8.5e-218 yhdR 2.6.1.1 E Aminotransferase
APOCAHHA_00954 3.7e-236 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
APOCAHHA_00955 1.3e-41 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APOCAHHA_00956 9.9e-62 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APOCAHHA_00957 6.6e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APOCAHHA_00959 1.3e-199 yhdY M Mechanosensitive ion channel
APOCAHHA_00960 3.6e-137 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
APOCAHHA_00961 2.1e-149 yheN G deacetylase
APOCAHHA_00962 1.4e-150 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
APOCAHHA_00963 6.2e-220 nhaC C Na H antiporter
APOCAHHA_00964 4.2e-82 nhaX T Belongs to the universal stress protein A family
APOCAHHA_00965 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
APOCAHHA_00966 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
APOCAHHA_00967 3.7e-103 yheG GM NAD(P)H-binding
APOCAHHA_00968 7e-27 sspB S spore protein
APOCAHHA_00969 3.2e-35 yheE S Family of unknown function (DUF5342)
APOCAHHA_00970 5.5e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
APOCAHHA_00971 9e-214 yheC HJ YheC/D like ATP-grasp
APOCAHHA_00972 1.3e-194 yheB S Belongs to the UPF0754 family
APOCAHHA_00973 9.5e-48 yheA S Belongs to the UPF0342 family
APOCAHHA_00974 1.5e-192 yhaZ L DNA alkylation repair enzyme
APOCAHHA_00975 1.8e-140 yhaX S haloacid dehalogenase-like hydrolase
APOCAHHA_00976 2.5e-286 hemZ H coproporphyrinogen III oxidase
APOCAHHA_00977 3.8e-205 yhaU P COG0475 Kef-type K transport systems, membrane components
APOCAHHA_00978 1.9e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
APOCAHHA_00980 2.6e-127 yhaR 5.3.3.18 I enoyl-CoA hydratase
APOCAHHA_00981 4.6e-25 S YhzD-like protein
APOCAHHA_00982 8.9e-167 yhaQ S ABC transporter, ATP-binding protein
APOCAHHA_00983 2.6e-212 yhaP CP COG1668 ABC-type Na efflux pump, permease component
APOCAHHA_00984 1e-218 yhaO L DNA repair exonuclease
APOCAHHA_00985 0.0 yhaN L AAA domain
APOCAHHA_00986 1.3e-176 yhaM L Shows a 3'-5' exoribonuclease activity
APOCAHHA_00987 1.6e-21 yhaL S Sporulation protein YhaL
APOCAHHA_00988 5.9e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APOCAHHA_00989 2.5e-89 yhaK S Putative zincin peptidase
APOCAHHA_00990 3.2e-53 yhaI S Protein of unknown function (DUF1878)
APOCAHHA_00991 2.9e-113 hpr K Negative regulator of protease production and sporulation
APOCAHHA_00992 7.8e-38 yhaH S YtxH-like protein
APOCAHHA_00993 1.2e-20
APOCAHHA_00994 1.1e-79 trpP S Tryptophan transporter TrpP
APOCAHHA_00995 3.2e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APOCAHHA_00996 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
APOCAHHA_00997 1.5e-135 ecsA V transporter (ATP-binding protein)
APOCAHHA_00998 4.9e-192 ecsB U ABC transporter
APOCAHHA_00999 3.5e-110 ecsC S EcsC protein family
APOCAHHA_01000 2.4e-220 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
APOCAHHA_01001 6e-239 yhfA C membrane
APOCAHHA_01002 2e-33 1.15.1.2 C Rubrerythrin
APOCAHHA_01003 2.7e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
APOCAHHA_01004 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APOCAHHA_01005 1.4e-198 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
APOCAHHA_01006 1.2e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
APOCAHHA_01007 3.2e-264 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
APOCAHHA_01008 8.7e-99 yhgD K Transcriptional regulator
APOCAHHA_01009 3e-214 yhgE S YhgE Pip N-terminal domain protein
APOCAHHA_01010 8.7e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APOCAHHA_01011 1.3e-134 yhfC S Putative membrane peptidase family (DUF2324)
APOCAHHA_01012 5.6e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
APOCAHHA_01013 8.6e-69 3.4.13.21 S ASCH
APOCAHHA_01014 5.4e-226 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOCAHHA_01015 5.2e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
APOCAHHA_01016 1.2e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
APOCAHHA_01017 4.6e-109 yhfK GM NmrA-like family
APOCAHHA_01018 3.4e-294 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
APOCAHHA_01019 1.3e-64 yhfM
APOCAHHA_01020 1.2e-233 yhfN 3.4.24.84 O Peptidase M48
APOCAHHA_01021 4.4e-195 aprE 3.4.21.62 O Belongs to the peptidase S8 family
APOCAHHA_01022 1.9e-69 VY92_01935 K acetyltransferase
APOCAHHA_01023 2.5e-178 yhfP 1.1.1.1 C Quinone oxidoreductase
APOCAHHA_01024 8.2e-158 yfmC M Periplasmic binding protein
APOCAHHA_01025 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
APOCAHHA_01026 7.7e-197 vraB 2.3.1.9 I Belongs to the thiolase family
APOCAHHA_01027 3.9e-257 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
APOCAHHA_01028 6.1e-89 bioY S BioY family
APOCAHHA_01029 8.6e-179 hemAT NT chemotaxis protein
APOCAHHA_01030 1.3e-298 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
APOCAHHA_01031 1e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_01032 1.6e-30 yhzC S IDEAL
APOCAHHA_01033 2.1e-108 comK K Competence transcription factor
APOCAHHA_01034 9.2e-164 IQ Enoyl-(Acyl carrier protein) reductase
APOCAHHA_01035 2.1e-39 yhjA S Excalibur calcium-binding domain
APOCAHHA_01036 1.6e-261 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOCAHHA_01037 2.6e-26 yhjC S Protein of unknown function (DUF3311)
APOCAHHA_01038 4.8e-55 yhjD
APOCAHHA_01039 4.5e-109 yhjE S SNARE associated Golgi protein
APOCAHHA_01040 2.5e-89 sipV 3.4.21.89 U Belongs to the peptidase S26 family
APOCAHHA_01041 1.6e-269 yhjG CH FAD binding domain
APOCAHHA_01042 1.3e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
APOCAHHA_01044 5e-191 abrB S membrane
APOCAHHA_01045 7.6e-198 EGP Transmembrane secretion effector
APOCAHHA_01046 4.8e-311 S Sugar transport-related sRNA regulator N-term
APOCAHHA_01047 2.2e-25 yhjQ C COG1145 Ferredoxin
APOCAHHA_01048 1.3e-75 yhjR S Rubrerythrin
APOCAHHA_01049 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
APOCAHHA_01050 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
APOCAHHA_01051 6.5e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APOCAHHA_01052 0.0 sbcC L COG0419 ATPase involved in DNA repair
APOCAHHA_01053 1.6e-48 yisB V COG1403 Restriction endonuclease
APOCAHHA_01054 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
APOCAHHA_01055 8.8e-66 gerPE S Spore germination protein GerPE
APOCAHHA_01056 6.3e-24 gerPD S Spore germination protein
APOCAHHA_01057 3.1e-54 gerPC S Spore germination protein
APOCAHHA_01058 4.4e-33 gerPB S cell differentiation
APOCAHHA_01059 1.9e-33 gerPA S Spore germination protein
APOCAHHA_01060 1.5e-19 yisI S Spo0E like sporulation regulatory protein
APOCAHHA_01061 2.6e-161 cotH M Spore Coat
APOCAHHA_01062 7.8e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
APOCAHHA_01063 6.6e-57 yisL S UPF0344 protein
APOCAHHA_01064 0.0 wprA O Belongs to the peptidase S8 family
APOCAHHA_01065 2.9e-99 yisN S Protein of unknown function (DUF2777)
APOCAHHA_01066 0.0 asnO 6.3.5.4 E Asparagine synthase
APOCAHHA_01067 3.4e-109 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
APOCAHHA_01068 4.9e-241 yisQ V Mate efflux family protein
APOCAHHA_01069 5e-159 yisR K Transcriptional regulator
APOCAHHA_01070 1.9e-178 purR K helix_turn _helix lactose operon repressor
APOCAHHA_01071 2.6e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
APOCAHHA_01072 1.5e-91 yisT S DinB family
APOCAHHA_01073 3.7e-100 argO S Lysine exporter protein LysE YggA
APOCAHHA_01074 9.3e-267 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APOCAHHA_01075 7.3e-30 mcbG S Pentapeptide repeats (9 copies)
APOCAHHA_01076 3.8e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APOCAHHA_01077 2.7e-111 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
APOCAHHA_01078 1.1e-220 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
APOCAHHA_01079 1.2e-137 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
APOCAHHA_01080 2.4e-116 comB 3.1.3.71 H Belongs to the ComB family
APOCAHHA_01081 1.2e-140 yitD 4.4.1.19 S synthase
APOCAHHA_01082 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APOCAHHA_01083 3.5e-213 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APOCAHHA_01084 6.3e-227 yitG EGP Major facilitator Superfamily
APOCAHHA_01085 1.8e-148 yitH K Acetyltransferase (GNAT) domain
APOCAHHA_01086 1.7e-78 yjcF S Acetyltransferase (GNAT) domain
APOCAHHA_01087 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
APOCAHHA_01088 3.3e-54 yajQ S Belongs to the UPF0234 family
APOCAHHA_01089 1.2e-157 cvfB S protein conserved in bacteria
APOCAHHA_01090 8.5e-94
APOCAHHA_01091 2.7e-166
APOCAHHA_01092 1.4e-95 S Sporulation delaying protein SdpA
APOCAHHA_01093 1.5e-58 K Transcriptional regulator PadR-like family
APOCAHHA_01094 4.3e-85
APOCAHHA_01095 1.4e-44 yitR S Domain of unknown function (DUF3784)
APOCAHHA_01096 5.7e-297 nprB 3.4.24.28 E Peptidase M4
APOCAHHA_01097 1.9e-155 yitS S protein conserved in bacteria
APOCAHHA_01098 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
APOCAHHA_01099 3.4e-74 ipi S Intracellular proteinase inhibitor
APOCAHHA_01100 3.4e-26 S Protein of unknown function (DUF3813)
APOCAHHA_01102 5.2e-150 yitU 3.1.3.104 S hydrolases of the HAD superfamily
APOCAHHA_01103 1.5e-138 yjfP S COG1073 Hydrolases of the alpha beta superfamily
APOCAHHA_01104 1.4e-50 yitW S metal-sulfur cluster biosynthetic enzyme
APOCAHHA_01105 1.5e-22 pilT S Proteolipid membrane potential modulator
APOCAHHA_01106 2.4e-259 yitY C D-arabinono-1,4-lactone oxidase
APOCAHHA_01107 5.3e-90 norB G Major Facilitator Superfamily
APOCAHHA_01108 1.6e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
APOCAHHA_01109 9.4e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
APOCAHHA_01110 2e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
APOCAHHA_01111 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
APOCAHHA_01112 1e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APOCAHHA_01113 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
APOCAHHA_01114 1.2e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APOCAHHA_01115 9.5e-28 yjzC S YjzC-like protein
APOCAHHA_01116 2.3e-16 yjzD S Protein of unknown function (DUF2929)
APOCAHHA_01117 2.3e-136 yjaU I carboxylic ester hydrolase activity
APOCAHHA_01118 1.5e-92 yjaV
APOCAHHA_01119 1.9e-183 med S Transcriptional activator protein med
APOCAHHA_01120 7.3e-26 comZ S ComZ
APOCAHHA_01121 5.8e-19 yjzB
APOCAHHA_01122 3.3e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APOCAHHA_01123 8.9e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APOCAHHA_01124 6e-143 yjaZ O Zn-dependent protease
APOCAHHA_01125 8.8e-184 appD P Belongs to the ABC transporter superfamily
APOCAHHA_01126 3e-184 appF E Belongs to the ABC transporter superfamily
APOCAHHA_01127 1.8e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
APOCAHHA_01128 2.2e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOCAHHA_01129 7.2e-156 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOCAHHA_01130 1.9e-146 yjbA S Belongs to the UPF0736 family
APOCAHHA_01131 1.3e-182 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
APOCAHHA_01132 8.8e-306 oppA E ABC transporter substrate-binding protein
APOCAHHA_01133 2.3e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOCAHHA_01134 2.2e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOCAHHA_01135 2.2e-105 oppD P Belongs to the ABC transporter superfamily
APOCAHHA_01136 2.9e-72 oppD P Belongs to the ABC transporter superfamily
APOCAHHA_01137 1.2e-171 oppF E Belongs to the ABC transporter superfamily
APOCAHHA_01138 2.2e-189 yjbB EGP Major Facilitator Superfamily
APOCAHHA_01139 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOCAHHA_01140 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APOCAHHA_01141 1.5e-110 yjbE P Integral membrane protein TerC family
APOCAHHA_01142 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APOCAHHA_01143 1.2e-203 yjbF S Competence protein
APOCAHHA_01144 7.1e-276 pepF E oligoendopeptidase F
APOCAHHA_01145 5.4e-77 pepF E oligoendopeptidase F
APOCAHHA_01146 1.7e-18
APOCAHHA_01147 1.6e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
APOCAHHA_01148 3.7e-72 yjbI S Bacterial-like globin
APOCAHHA_01149 1e-99 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APOCAHHA_01150 3.3e-98 yjbK S protein conserved in bacteria
APOCAHHA_01151 1e-60 yjbL S Belongs to the UPF0738 family
APOCAHHA_01152 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
APOCAHHA_01153 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APOCAHHA_01154 4e-151 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APOCAHHA_01155 1.6e-126 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
APOCAHHA_01156 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APOCAHHA_01157 1.9e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APOCAHHA_01158 1.1e-104 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
APOCAHHA_01159 1.7e-207 thiO 1.4.3.19 E Glycine oxidase
APOCAHHA_01160 2.6e-29 thiS H thiamine diphosphate biosynthetic process
APOCAHHA_01161 2.5e-133 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
APOCAHHA_01162 1.3e-182 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APOCAHHA_01163 3.2e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APOCAHHA_01164 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
APOCAHHA_01165 1.6e-51 yjbX S Spore coat protein
APOCAHHA_01166 3.3e-77 cotZ S Spore coat protein
APOCAHHA_01167 8.4e-95 cotY S Spore coat protein Z
APOCAHHA_01168 5.4e-68 cotX S Spore Coat Protein X and V domain
APOCAHHA_01169 2e-23 cotW
APOCAHHA_01170 3.6e-48 cotV S Spore Coat Protein X and V domain
APOCAHHA_01171 3.3e-56 yjcA S Protein of unknown function (DUF1360)
APOCAHHA_01174 4.9e-38 spoVIF S Stage VI sporulation protein F
APOCAHHA_01175 0.0 yjcD 3.6.4.12 L DNA helicase
APOCAHHA_01176 3.2e-37
APOCAHHA_01177 2.8e-70 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOCAHHA_01178 1.4e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
APOCAHHA_01179 2.2e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
APOCAHHA_01180 1.4e-212 metB 2.5.1.48, 4.4.1.8 E cystathionine
APOCAHHA_01181 7.4e-214 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APOCAHHA_01182 1.8e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
APOCAHHA_01183 1.3e-210 yjcL S Protein of unknown function (DUF819)
APOCAHHA_01185 3.3e-17
APOCAHHA_01186 1.1e-30
APOCAHHA_01187 5.2e-246 M nucleic acid phosphodiester bond hydrolysis
APOCAHHA_01188 4.5e-18
APOCAHHA_01190 4.7e-130 S response regulator aspartate phosphatase
APOCAHHA_01191 3.5e-45 yjcS S Antibiotic biosynthesis monooxygenase
APOCAHHA_01192 1.7e-40 yjcN
APOCAHHA_01193 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
APOCAHHA_01194 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
APOCAHHA_01195 9.6e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
APOCAHHA_01196 1e-45 yjdF S Protein of unknown function (DUF2992)
APOCAHHA_01197 3e-87 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
APOCAHHA_01199 9.2e-78 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APOCAHHA_01200 4.2e-29 S Domain of unknown function (DUF4177)
APOCAHHA_01201 6.8e-48 yjdJ S Domain of unknown function (DUF4306)
APOCAHHA_01202 3.5e-169 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APOCAHHA_01204 1.5e-258 xynD 3.5.1.104 G Polysaccharide deacetylase
APOCAHHA_01205 1.8e-81 S Protein of unknown function (DUF2690)
APOCAHHA_01206 2e-19 yjfB S Putative motility protein
APOCAHHA_01207 1.5e-161 yjfC O Predicted Zn-dependent protease (DUF2268)
APOCAHHA_01208 1.9e-33 T PhoQ Sensor
APOCAHHA_01209 2.2e-102 yjgB S Domain of unknown function (DUF4309)
APOCAHHA_01210 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
APOCAHHA_01211 1.3e-94 yjgD S Protein of unknown function (DUF1641)
APOCAHHA_01213 1.1e-110 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
APOCAHHA_01215 4.1e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
APOCAHHA_01216 2.2e-205 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APOCAHHA_01217 8.2e-30
APOCAHHA_01218 6.6e-137 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APOCAHHA_01219 2.8e-121 ybbM S transport system, permease component
APOCAHHA_01220 8.6e-131 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
APOCAHHA_01221 4e-173 yjlA EG Putative multidrug resistance efflux transporter
APOCAHHA_01222 2.3e-84 yjlB S Cupin domain
APOCAHHA_01223 1.2e-65 yjlC S Protein of unknown function (DUF1641)
APOCAHHA_01224 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
APOCAHHA_01225 6.3e-276 uxaC 5.3.1.12 G glucuronate isomerase
APOCAHHA_01226 2.8e-244 yjmB G symporter YjmB
APOCAHHA_01227 2.8e-177 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
APOCAHHA_01228 6.9e-184 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
APOCAHHA_01229 1.2e-210 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
APOCAHHA_01230 3e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_01231 1.9e-202 exuT G Sugar (and other) transporter
APOCAHHA_01232 1.9e-178 exuR K transcriptional
APOCAHHA_01233 1.1e-267 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
APOCAHHA_01234 9e-281 uxaA 4.2.1.7, 4.4.1.24 G Altronate
APOCAHHA_01235 1.6e-129 MA20_18170 S membrane transporter protein
APOCAHHA_01236 2.6e-77 yjoA S DinB family
APOCAHHA_01237 6.3e-243 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
APOCAHHA_01238 8.7e-212 S response regulator aspartate phosphatase
APOCAHHA_01240 1.5e-39 S YCII-related domain
APOCAHHA_01241 6.3e-163 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
APOCAHHA_01242 6.1e-61 yjqA S Bacterial PH domain
APOCAHHA_01243 3.8e-105 yjqB S Pfam:DUF867
APOCAHHA_01244 9.5e-155 ydbD P Catalase
APOCAHHA_01245 3.6e-108 xkdA E IrrE N-terminal-like domain
APOCAHHA_01246 7e-56 xre K Helix-turn-helix XRE-family like proteins
APOCAHHA_01248 1.1e-137 xkdB K sequence-specific DNA binding
APOCAHHA_01249 1.7e-116 xkdC L Bacterial dnaA protein
APOCAHHA_01252 6e-10 yqaO S Phage-like element PBSX protein XtrA
APOCAHHA_01253 3.2e-81 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
APOCAHHA_01254 3.8e-137 xtmA L phage terminase small subunit
APOCAHHA_01255 2.1e-249 xtmB S phage terminase, large subunit
APOCAHHA_01256 3e-284 yqbA S portal protein
APOCAHHA_01257 2.2e-132 yqbD 2.1.1.72 L Putative phage serine protease XkdF
APOCAHHA_01258 5.8e-169 xkdG S Phage capsid family
APOCAHHA_01259 1.9e-62 yqbG S Protein of unknown function (DUF3199)
APOCAHHA_01260 4.4e-61 yqbH S Domain of unknown function (DUF3599)
APOCAHHA_01261 1.3e-82 xkdI S Bacteriophage HK97-gp10, putative tail-component
APOCAHHA_01262 9.6e-74 xkdJ
APOCAHHA_01263 1.9e-253 xkdK S Phage tail sheath C-terminal domain
APOCAHHA_01264 6.1e-76 xkdM S Phage tail tube protein
APOCAHHA_01265 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
APOCAHHA_01266 1.1e-265 xkdO L Transglycosylase SLT domain
APOCAHHA_01267 1.5e-118 xkdP S Lysin motif
APOCAHHA_01268 2.6e-180 yqbQ 3.2.1.96 G NLP P60 protein
APOCAHHA_01269 1e-38 xkdR S Protein of unknown function (DUF2577)
APOCAHHA_01270 1.5e-68 xkdS S Protein of unknown function (DUF2634)
APOCAHHA_01271 1.3e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
APOCAHHA_01272 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
APOCAHHA_01273 1.6e-39
APOCAHHA_01274 2.8e-141
APOCAHHA_01276 3.5e-11 S Phage uncharacterised protein (Phage_XkdX)
APOCAHHA_01277 8.6e-36 xhlA S Haemolysin XhlA
APOCAHHA_01278 9.3e-40 xhlB S SPP1 phage holin
APOCAHHA_01279 1.5e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOCAHHA_01281 1.9e-22 spoIISB S Stage II sporulation protein SB
APOCAHHA_01282 2.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
APOCAHHA_01283 9.2e-173 pit P phosphate transporter
APOCAHHA_01284 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
APOCAHHA_01285 4.1e-237 steT E amino acid
APOCAHHA_01286 1.3e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
APOCAHHA_01287 2.3e-306 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APOCAHHA_01288 8.7e-176 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APOCAHHA_01290 3e-198 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APOCAHHA_01291 3e-129 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
APOCAHHA_01292 8.8e-153 dppA E D-aminopeptidase
APOCAHHA_01293 9.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOCAHHA_01294 1.1e-173 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APOCAHHA_01295 3.6e-185 dppD P Belongs to the ABC transporter superfamily
APOCAHHA_01296 0.0 dppE E ABC transporter substrate-binding protein
APOCAHHA_01297 1.6e-171 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
APOCAHHA_01298 8.5e-196 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APOCAHHA_01299 5.5e-161 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APOCAHHA_01300 1.8e-184 ykfD E Belongs to the ABC transporter superfamily
APOCAHHA_01301 8.7e-198 pgl 3.1.1.31 G 6-phosphogluconolactonase
APOCAHHA_01302 1.1e-145 ykgA E Amidinotransferase
APOCAHHA_01303 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
APOCAHHA_01304 2.2e-221 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APOCAHHA_01306 2.3e-128 ykjA S Protein of unknown function (DUF421)
APOCAHHA_01307 2.8e-88 ykkA S Protein of unknown function (DUF664)
APOCAHHA_01308 1.1e-92 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APOCAHHA_01309 1.5e-53 ykkC P Multidrug resistance protein
APOCAHHA_01310 9.1e-50 ykkD P Multidrug resistance protein
APOCAHHA_01311 7.3e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
APOCAHHA_01312 5.7e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APOCAHHA_01313 4.2e-223 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APOCAHHA_01314 1.4e-69 ohrA O Organic hydroperoxide resistance protein
APOCAHHA_01315 3.7e-70 ohrR K COG1846 Transcriptional regulators
APOCAHHA_01316 4.2e-71 ohrB O Organic hydroperoxide resistance protein
APOCAHHA_01317 1.3e-84 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
APOCAHHA_01318 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APOCAHHA_01319 3.3e-175 isp O Belongs to the peptidase S8 family
APOCAHHA_01320 7e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APOCAHHA_01321 3.4e-135 ykoC P Cobalt transport protein
APOCAHHA_01322 5.4e-295 P ABC transporter, ATP-binding protein
APOCAHHA_01323 2.4e-91 ykoE S ABC-type cobalt transport system, permease component
APOCAHHA_01324 1.7e-105 ykoF S YKOF-related Family
APOCAHHA_01325 1.9e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_01326 3.3e-229 ykoH 2.7.13.3 T Histidine kinase
APOCAHHA_01327 1.7e-101 ykoI S Peptidase propeptide and YPEB domain
APOCAHHA_01328 6e-75 ykoJ S Peptidase propeptide and YPEB domain
APOCAHHA_01331 1.5e-221 mgtE P Acts as a magnesium transporter
APOCAHHA_01332 1.4e-53 tnrA K transcriptional
APOCAHHA_01333 1.7e-17
APOCAHHA_01334 1.3e-24 ykoL
APOCAHHA_01335 1.3e-81 mhqR K transcriptional
APOCAHHA_01336 1e-193 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
APOCAHHA_01337 8e-94 ykoP G polysaccharide deacetylase
APOCAHHA_01338 1.2e-151 ykoQ S Calcineurin-like phosphoesterase superfamily domain
APOCAHHA_01339 0.0 ykoS
APOCAHHA_01340 2.6e-183 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APOCAHHA_01341 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
APOCAHHA_01342 2.6e-158 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
APOCAHHA_01343 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
APOCAHHA_01344 1.9e-102 ykoX S membrane-associated protein
APOCAHHA_01345 5.5e-136 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
APOCAHHA_01346 2.1e-129 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOCAHHA_01347 3.5e-107 rsgI S Anti-sigma factor N-terminus
APOCAHHA_01348 1.9e-26 sspD S small acid-soluble spore protein
APOCAHHA_01349 1.8e-122 ykrK S Domain of unknown function (DUF1836)
APOCAHHA_01350 2.5e-153 htpX O Belongs to the peptidase M48B family
APOCAHHA_01351 1.6e-236 ktrB P COG0168 Trk-type K transport systems, membrane components
APOCAHHA_01352 1.2e-10 ydfR S Protein of unknown function (DUF421)
APOCAHHA_01353 7.9e-17 ykzE
APOCAHHA_01354 1.7e-185 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
APOCAHHA_01355 0.0 kinE 2.7.13.3 T Histidine kinase
APOCAHHA_01356 7e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APOCAHHA_01358 1.1e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
APOCAHHA_01359 2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
APOCAHHA_01360 2.2e-128 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APOCAHHA_01361 4.7e-224 mtnE 2.6.1.83 E Aminotransferase
APOCAHHA_01362 1.8e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
APOCAHHA_01363 1.6e-131 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
APOCAHHA_01364 7e-110 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
APOCAHHA_01365 1.7e-93 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
APOCAHHA_01366 1.2e-49 XK27_09985 S Protein of unknown function (DUF1232)
APOCAHHA_01367 6.4e-09 S Spo0E like sporulation regulatory protein
APOCAHHA_01368 2.3e-59 eag
APOCAHHA_01369 2.2e-271 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
APOCAHHA_01370 1.3e-75 ykvE K transcriptional
APOCAHHA_01371 3.3e-125 motB N Flagellar motor protein
APOCAHHA_01372 1.4e-137 motA N flagellar motor
APOCAHHA_01373 0.0 clpE O Belongs to the ClpA ClpB family
APOCAHHA_01374 4e-179 ykvI S membrane
APOCAHHA_01375 2.3e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
APOCAHHA_01376 1.1e-80 queD 4.1.2.50, 4.2.3.12 H synthase
APOCAHHA_01377 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
APOCAHHA_01378 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
APOCAHHA_01379 7e-28 K Cro/C1-type HTH DNA-binding domain
APOCAHHA_01380 3.2e-47
APOCAHHA_01381 7.5e-183 I Pfam Lipase (class 3)
APOCAHHA_01382 7.7e-16 S Protein of unknown function (DUF1433)
APOCAHHA_01383 1.7e-42 ykvR S Protein of unknown function (DUF3219)
APOCAHHA_01384 6e-25 ykvS S protein conserved in bacteria
APOCAHHA_01385 7.9e-28
APOCAHHA_01386 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
APOCAHHA_01387 1e-235 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOCAHHA_01388 3.5e-88 stoA CO thiol-disulfide
APOCAHHA_01389 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
APOCAHHA_01390 3.8e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
APOCAHHA_01392 1.2e-172 ykvZ 5.1.1.1 K Transcriptional regulator
APOCAHHA_01393 6.5e-127 glcT K antiterminator
APOCAHHA_01394 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOCAHHA_01395 2.1e-39 ptsH G phosphocarrier protein HPr
APOCAHHA_01396 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APOCAHHA_01397 7.2e-39 splA S Transcriptional regulator
APOCAHHA_01398 2.7e-199 splB 4.1.99.14 L Spore photoproduct lyase
APOCAHHA_01399 1.6e-123 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOCAHHA_01400 1.2e-253 mcpC NT chemotaxis protein
APOCAHHA_01401 1.8e-156 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
APOCAHHA_01402 3e-13 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
APOCAHHA_01403 7.5e-122 ykwD J protein with SCP PR1 domains
APOCAHHA_01404 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
APOCAHHA_01405 0.0 pilS 2.7.13.3 T Histidine kinase
APOCAHHA_01406 3e-223 patA 2.6.1.1 E Aminotransferase
APOCAHHA_01407 2.2e-15
APOCAHHA_01408 1.5e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
APOCAHHA_01409 1.7e-84 ykyB S YkyB-like protein
APOCAHHA_01410 2.1e-233 ykuC EGP Major facilitator Superfamily
APOCAHHA_01411 1.5e-83 ykuD S protein conserved in bacteria
APOCAHHA_01412 1.1e-161 ykuE S Metallophosphoesterase
APOCAHHA_01413 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_01414 9.7e-233 ykuI T Diguanylate phosphodiesterase
APOCAHHA_01415 3.9e-37 ykuJ S protein conserved in bacteria
APOCAHHA_01416 1.9e-92 ykuK S Ribonuclease H-like
APOCAHHA_01417 8e-28 ykzF S Antirepressor AbbA
APOCAHHA_01418 1.6e-76 ykuL S CBS domain
APOCAHHA_01419 7.9e-168 ccpC K Transcriptional regulator
APOCAHHA_01420 4.4e-80 fld C Flavodoxin domain
APOCAHHA_01421 2.6e-166 ykuO
APOCAHHA_01422 1.1e-75 fld C Flavodoxin
APOCAHHA_01423 2.4e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APOCAHHA_01424 1.5e-211 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APOCAHHA_01425 2e-36 ykuS S Belongs to the UPF0180 family
APOCAHHA_01426 7e-139 ykuT M Mechanosensitive ion channel
APOCAHHA_01427 8.7e-101 ykuU O Alkyl hydroperoxide reductase
APOCAHHA_01428 9.4e-80 ykuV CO thiol-disulfide
APOCAHHA_01429 2.5e-93 rok K Repressor of ComK
APOCAHHA_01430 4e-133 yknT
APOCAHHA_01431 3.5e-103 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
APOCAHHA_01432 4.4e-186 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APOCAHHA_01433 3.5e-241 moeA 2.10.1.1 H molybdopterin
APOCAHHA_01434 6e-91 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
APOCAHHA_01435 2.3e-81 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
APOCAHHA_01436 7e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
APOCAHHA_01437 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
APOCAHHA_01438 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
APOCAHHA_01439 5.6e-100 yknW S Yip1 domain
APOCAHHA_01440 5.6e-150 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APOCAHHA_01441 2.6e-121 macB V ABC transporter, ATP-binding protein
APOCAHHA_01442 3.1e-207 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
APOCAHHA_01443 1.2e-135 fruR K Transcriptional regulator
APOCAHHA_01444 2.5e-164 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
APOCAHHA_01445 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
APOCAHHA_01446 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
APOCAHHA_01447 8.1e-39 ykoA
APOCAHHA_01448 7.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APOCAHHA_01449 9e-159 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APOCAHHA_01450 9.8e-233 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
APOCAHHA_01451 1.1e-12 S Uncharacterized protein YkpC
APOCAHHA_01452 7.7e-183 mreB D Rod-share determining protein MreBH
APOCAHHA_01453 1.9e-43 abrB K of stationary sporulation gene expression
APOCAHHA_01454 8.6e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
APOCAHHA_01455 3e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
APOCAHHA_01456 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
APOCAHHA_01457 2.4e-309 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
APOCAHHA_01458 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APOCAHHA_01459 8.2e-31 ykzG S Belongs to the UPF0356 family
APOCAHHA_01460 2.4e-142 ykrA S hydrolases of the HAD superfamily
APOCAHHA_01461 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APOCAHHA_01463 2.4e-97 recN L Putative cell-wall binding lipoprotein
APOCAHHA_01464 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APOCAHHA_01465 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APOCAHHA_01466 8.4e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APOCAHHA_01467 1.2e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APOCAHHA_01468 8.5e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
APOCAHHA_01469 2.7e-10 S SR1 protein
APOCAHHA_01470 1.1e-262 speA 4.1.1.19 E Arginine
APOCAHHA_01471 1e-41 yktA S Belongs to the UPF0223 family
APOCAHHA_01472 3.9e-116 yktB S Belongs to the UPF0637 family
APOCAHHA_01473 7.1e-26 ykzI
APOCAHHA_01474 9.1e-147 suhB 3.1.3.25 G Inositol monophosphatase
APOCAHHA_01475 1.7e-73 ykzC S Acetyltransferase (GNAT) family
APOCAHHA_01476 1.1e-156 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
APOCAHHA_01477 1.4e-287 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
APOCAHHA_01478 0.0 ylaA
APOCAHHA_01479 8.6e-41 ylaB
APOCAHHA_01480 2.1e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_01481 2e-11 sigC S Putative zinc-finger
APOCAHHA_01482 1.8e-33 ylaE
APOCAHHA_01483 1.8e-21 S Family of unknown function (DUF5325)
APOCAHHA_01484 0.0 typA T GTP-binding protein TypA
APOCAHHA_01485 9.5e-47 ylaH S YlaH-like protein
APOCAHHA_01486 2.5e-32 ylaI S protein conserved in bacteria
APOCAHHA_01487 9.8e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APOCAHHA_01488 2.6e-247 phoH T ATPase related to phosphate starvation-inducible protein PhoH
APOCAHHA_01489 8.9e-81 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
APOCAHHA_01490 4.4e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
APOCAHHA_01491 1.9e-43 ylaN S Belongs to the UPF0358 family
APOCAHHA_01492 2.5e-209 ftsW D Belongs to the SEDS family
APOCAHHA_01493 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APOCAHHA_01494 4.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
APOCAHHA_01495 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APOCAHHA_01496 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
APOCAHHA_01497 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APOCAHHA_01498 3.7e-111 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
APOCAHHA_01499 5.1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
APOCAHHA_01500 4.7e-160 ctaG S cytochrome c oxidase
APOCAHHA_01501 3.2e-59 ylbA S YugN-like family
APOCAHHA_01502 2.6e-74 ylbB T COG0517 FOG CBS domain
APOCAHHA_01503 1.7e-198 ylbC S protein with SCP PR1 domains
APOCAHHA_01504 4.2e-60 ylbD S Putative coat protein
APOCAHHA_01505 4.3e-36 ylbE S YlbE-like protein
APOCAHHA_01506 1.8e-75 ylbF S Belongs to the UPF0342 family
APOCAHHA_01507 7.5e-39 ylbG S UPF0298 protein
APOCAHHA_01508 4.6e-97 rsmD 2.1.1.171 L Methyltransferase
APOCAHHA_01509 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APOCAHHA_01510 1.2e-217 ylbJ S Sporulation integral membrane protein YlbJ
APOCAHHA_01511 3.7e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
APOCAHHA_01512 2.9e-182 ylbL T Belongs to the peptidase S16 family
APOCAHHA_01513 1.5e-220 ylbM S Belongs to the UPF0348 family
APOCAHHA_01514 5.1e-90 yceD S metal-binding, possibly nucleic acid-binding protein
APOCAHHA_01515 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
APOCAHHA_01516 2.2e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
APOCAHHA_01517 6.8e-89 ylbP K n-acetyltransferase
APOCAHHA_01518 4.9e-157 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APOCAHHA_01519 4.5e-302 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
APOCAHHA_01520 2.9e-78 mraZ K Belongs to the MraZ family
APOCAHHA_01521 3.1e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APOCAHHA_01522 6.4e-44 ftsL D Essential cell division protein
APOCAHHA_01523 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
APOCAHHA_01524 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
APOCAHHA_01525 1.9e-278 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APOCAHHA_01526 4.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APOCAHHA_01527 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APOCAHHA_01528 7.5e-186 spoVE D Belongs to the SEDS family
APOCAHHA_01529 6.3e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APOCAHHA_01530 1.5e-166 murB 1.3.1.98 M cell wall formation
APOCAHHA_01531 1.7e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APOCAHHA_01532 5.4e-103 ylxW S protein conserved in bacteria
APOCAHHA_01533 1.9e-113 ylxX S protein conserved in bacteria
APOCAHHA_01534 3.3e-56 sbp S small basic protein
APOCAHHA_01535 1.2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APOCAHHA_01536 3.4e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APOCAHHA_01537 0.0 bpr O COG1404 Subtilisin-like serine proteases
APOCAHHA_01538 2.9e-168 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
APOCAHHA_01539 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOCAHHA_01540 6.2e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOCAHHA_01541 5.3e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
APOCAHHA_01542 5.6e-247 argE 3.5.1.16 E Acetylornithine deacetylase
APOCAHHA_01543 2.4e-37 ylmC S sporulation protein
APOCAHHA_01544 6.1e-154 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
APOCAHHA_01545 1.6e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APOCAHHA_01546 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APOCAHHA_01547 1.3e-39 yggT S membrane
APOCAHHA_01548 1.2e-135 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
APOCAHHA_01549 2.6e-67 divIVA D Cell division initiation protein
APOCAHHA_01550 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APOCAHHA_01551 8.5e-63 dksA T COG1734 DnaK suppressor protein
APOCAHHA_01552 6.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APOCAHHA_01553 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APOCAHHA_01554 6.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APOCAHHA_01555 4.4e-231 pyrP F Xanthine uracil
APOCAHHA_01556 9.4e-164 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
APOCAHHA_01557 2.7e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APOCAHHA_01558 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APOCAHHA_01559 0.0 carB 6.3.5.5 F Belongs to the CarB family
APOCAHHA_01560 5e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
APOCAHHA_01561 1.6e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APOCAHHA_01562 2e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APOCAHHA_01563 3.6e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APOCAHHA_01564 1.1e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
APOCAHHA_01565 6.6e-177 cysP P phosphate transporter
APOCAHHA_01566 1.8e-220 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
APOCAHHA_01567 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
APOCAHHA_01568 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
APOCAHHA_01569 9.6e-141 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
APOCAHHA_01570 1e-79 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
APOCAHHA_01571 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
APOCAHHA_01572 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
APOCAHHA_01573 1.4e-153 yloC S stress-induced protein
APOCAHHA_01574 1.5e-40 ylzA S Belongs to the UPF0296 family
APOCAHHA_01575 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
APOCAHHA_01576 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APOCAHHA_01577 2.7e-219 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APOCAHHA_01578 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APOCAHHA_01579 4e-81 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APOCAHHA_01580 2e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APOCAHHA_01581 1e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APOCAHHA_01582 1.5e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APOCAHHA_01583 4.3e-138 stp 3.1.3.16 T phosphatase
APOCAHHA_01584 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
APOCAHHA_01585 9.5e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APOCAHHA_01586 9.7e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
APOCAHHA_01587 2.7e-117 thiN 2.7.6.2 H thiamine pyrophosphokinase
APOCAHHA_01588 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
APOCAHHA_01589 2.7e-58 asp S protein conserved in bacteria
APOCAHHA_01590 3.6e-291 yloV S kinase related to dihydroxyacetone kinase
APOCAHHA_01591 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
APOCAHHA_01592 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
APOCAHHA_01593 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APOCAHHA_01594 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
APOCAHHA_01595 9.3e-165 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APOCAHHA_01596 8e-166 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APOCAHHA_01597 1.4e-128 IQ reductase
APOCAHHA_01598 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APOCAHHA_01599 1.2e-109 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APOCAHHA_01600 0.0 smc D Required for chromosome condensation and partitioning
APOCAHHA_01601 7.5e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APOCAHHA_01602 3e-123 S Phosphotransferase enzyme family
APOCAHHA_01603 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APOCAHHA_01604 1.8e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APOCAHHA_01605 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
APOCAHHA_01606 6.4e-35 ylqC S Belongs to the UPF0109 family
APOCAHHA_01607 3.1e-60 ylqD S YlqD protein
APOCAHHA_01608 2.5e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APOCAHHA_01609 4.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
APOCAHHA_01610 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APOCAHHA_01611 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APOCAHHA_01612 3.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APOCAHHA_01613 3.7e-270 ylqG
APOCAHHA_01614 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
APOCAHHA_01615 4.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
APOCAHHA_01616 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APOCAHHA_01617 4.7e-160 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
APOCAHHA_01618 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APOCAHHA_01619 4.8e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APOCAHHA_01620 9.7e-169 xerC L tyrosine recombinase XerC
APOCAHHA_01621 7.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
APOCAHHA_01622 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
APOCAHHA_01623 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
APOCAHHA_01624 5.2e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
APOCAHHA_01625 8.4e-73 flgC N Belongs to the flagella basal body rod proteins family
APOCAHHA_01626 1.9e-31 fliE N Flagellar hook-basal body
APOCAHHA_01627 8.6e-27 fliF N The M ring may be actively involved in energy transduction
APOCAHHA_01628 7.8e-207 fliF N The M ring may be actively involved in energy transduction
APOCAHHA_01629 9.7e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APOCAHHA_01630 5.3e-104 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
APOCAHHA_01631 2e-239 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
APOCAHHA_01632 9.4e-69 fliJ N Flagellar biosynthesis chaperone
APOCAHHA_01633 3.2e-35 ylxF S MgtE intracellular N domain
APOCAHHA_01634 1.8e-185 fliK N Flagellar hook-length control protein
APOCAHHA_01635 9.6e-71 flgD N Flagellar basal body rod modification protein
APOCAHHA_01636 2.1e-135 flgG N Flagellar basal body rod
APOCAHHA_01637 8.4e-51 fliL N Controls the rotational direction of flagella during chemotaxis
APOCAHHA_01638 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APOCAHHA_01639 4.3e-174 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
APOCAHHA_01640 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
APOCAHHA_01641 1.1e-92 fliZ N Flagellar biosynthesis protein, FliO
APOCAHHA_01642 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
APOCAHHA_01643 2.2e-36 fliQ N Role in flagellar biosynthesis
APOCAHHA_01644 3.1e-131 fliR N Flagellar biosynthetic protein FliR
APOCAHHA_01645 9.9e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APOCAHHA_01646 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APOCAHHA_01647 4.5e-189 flhF N Flagellar biosynthesis regulator FlhF
APOCAHHA_01648 2e-155 flhG D Belongs to the ParA family
APOCAHHA_01649 1.8e-190 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
APOCAHHA_01650 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
APOCAHHA_01651 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
APOCAHHA_01652 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
APOCAHHA_01653 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
APOCAHHA_01654 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOCAHHA_01655 4.5e-67 ylxL
APOCAHHA_01656 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
APOCAHHA_01657 2.2e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APOCAHHA_01658 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
APOCAHHA_01659 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APOCAHHA_01660 4.1e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APOCAHHA_01661 1.5e-136 cdsA 2.7.7.41 S Belongs to the CDS family
APOCAHHA_01662 3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
APOCAHHA_01663 2.2e-232 rasP M zinc metalloprotease
APOCAHHA_01664 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APOCAHHA_01665 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APOCAHHA_01666 1.6e-79 rimP S Required for maturation of 30S ribosomal subunits
APOCAHHA_01667 2.5e-203 nusA K Participates in both transcription termination and antitermination
APOCAHHA_01668 5.7e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
APOCAHHA_01669 3.1e-47 ylxQ J ribosomal protein
APOCAHHA_01670 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APOCAHHA_01671 3e-44 ylxP S protein conserved in bacteria
APOCAHHA_01672 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APOCAHHA_01673 7.5e-169 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APOCAHHA_01674 6.9e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
APOCAHHA_01675 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APOCAHHA_01676 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
APOCAHHA_01677 5.7e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
APOCAHHA_01678 4.8e-232 pepR S Belongs to the peptidase M16 family
APOCAHHA_01679 2.2e-41 ymxH S YlmC YmxH family
APOCAHHA_01680 3e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
APOCAHHA_01681 2.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
APOCAHHA_01682 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APOCAHHA_01683 6.1e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
APOCAHHA_01684 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APOCAHHA_01685 9.6e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APOCAHHA_01686 4.3e-127 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
APOCAHHA_01687 4.4e-32 S YlzJ-like protein
APOCAHHA_01688 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
APOCAHHA_01689 1.4e-133 ymfC K Transcriptional regulator
APOCAHHA_01690 5.5e-204 ymfD EGP Major facilitator Superfamily
APOCAHHA_01691 1.9e-226 ymfF S Peptidase M16
APOCAHHA_01692 1.6e-238 ymfH S zinc protease
APOCAHHA_01693 2.3e-125 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
APOCAHHA_01694 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
APOCAHHA_01695 3e-142 ymfK S Protein of unknown function (DUF3388)
APOCAHHA_01696 6.1e-123 ymfM S protein conserved in bacteria
APOCAHHA_01697 3.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APOCAHHA_01698 9.3e-231 cinA 3.5.1.42 S Belongs to the CinA family
APOCAHHA_01699 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APOCAHHA_01700 2.2e-210 pbpX V Beta-lactamase
APOCAHHA_01701 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
APOCAHHA_01702 1.9e-152 ymdB S protein conserved in bacteria
APOCAHHA_01703 1.2e-36 spoVS S Stage V sporulation protein S
APOCAHHA_01704 8.1e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
APOCAHHA_01705 4.7e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APOCAHHA_01706 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
APOCAHHA_01707 7.7e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
APOCAHHA_01708 9.4e-87 cotE S Spore coat protein
APOCAHHA_01709 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APOCAHHA_01710 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APOCAHHA_01714 1e-65 S Regulatory protein YrvL
APOCAHHA_01715 4.8e-94 ymcC S Membrane
APOCAHHA_01716 3.4e-101 pksA K Transcriptional regulator
APOCAHHA_01717 1.7e-60 ymzB
APOCAHHA_01718 7.8e-157 ymaE S Metallo-beta-lactamase superfamily
APOCAHHA_01719 1.1e-245 aprX O Belongs to the peptidase S8 family
APOCAHHA_01720 1.9e-07 K Transcriptional regulator
APOCAHHA_01721 1e-125 ymaC S Replication protein
APOCAHHA_01722 1.9e-77 ymaD O redox protein, regulator of disulfide bond formation
APOCAHHA_01723 1.5e-53 ebrB P COG2076 Membrane transporters of cations and cationic drugs
APOCAHHA_01724 4.5e-49 ebrA P Small Multidrug Resistance protein
APOCAHHA_01726 4.7e-43 ymaF S YmaF family
APOCAHHA_01727 1.6e-171 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APOCAHHA_01728 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
APOCAHHA_01729 3.1e-22
APOCAHHA_01730 4.5e-22 ymzA
APOCAHHA_01731 1.5e-65 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
APOCAHHA_01732 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APOCAHHA_01733 1.3e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APOCAHHA_01734 7.6e-109 ymaB
APOCAHHA_01735 2e-111 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOCAHHA_01736 1.1e-69 spoVK O stage V sporulation protein K
APOCAHHA_01737 1.6e-85 spoVK O stage V sporulation protein K
APOCAHHA_01738 2.1e-109 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APOCAHHA_01739 2.6e-92 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APOCAHHA_01740 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
APOCAHHA_01741 3.3e-68 glnR K transcriptional
APOCAHHA_01742 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
APOCAHHA_01743 1.1e-23
APOCAHHA_01744 6.7e-31
APOCAHHA_01745 7.1e-243 M nucleic acid phosphodiester bond hydrolysis
APOCAHHA_01747 3.9e-69
APOCAHHA_01748 3.2e-20
APOCAHHA_01749 5.3e-84 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APOCAHHA_01750 7.7e-46
APOCAHHA_01752 1.3e-101 S aspartate phosphatase
APOCAHHA_01753 9.8e-94 ynaD J Acetyltransferase (GNAT) domain
APOCAHHA_01754 1.3e-114 ynaE S Domain of unknown function (DUF3885)
APOCAHHA_01756 1.6e-79 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
APOCAHHA_01757 9e-240 xynT G MFS/sugar transport protein
APOCAHHA_01758 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
APOCAHHA_01759 3e-207 xylR GK ROK family
APOCAHHA_01760 1.2e-255 xylA 5.3.1.5 G Belongs to the xylose isomerase family
APOCAHHA_01761 4.8e-274 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
APOCAHHA_01763 3.4e-121 3.2.1.8 G Glycosyl hydrolases family 11
APOCAHHA_01764 3.9e-97 yokF 3.1.31.1 L RNA catabolic process
APOCAHHA_01765 1.6e-239 iolT EGP Major facilitator Superfamily
APOCAHHA_01766 1.2e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APOCAHHA_01767 5.3e-60 yncE S Protein of unknown function (DUF2691)
APOCAHHA_01768 2e-76 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
APOCAHHA_01769 1.7e-159 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APOCAHHA_01770 4e-32
APOCAHHA_01772 5.5e-119 S Domain of unknown function, YrpD
APOCAHHA_01775 1.6e-22 tatA U protein secretion
APOCAHHA_01776 7.2e-68
APOCAHHA_01777 8.6e-75 yndB S Activator of Hsp90 ATPase homolog 1-like protein
APOCAHHA_01779 8.3e-140 yndG S DoxX-like family
APOCAHHA_01780 2.7e-294 yndJ S YndJ-like protein
APOCAHHA_01782 2.8e-129 yndL S Replication protein
APOCAHHA_01783 8.3e-73 yndM S Protein of unknown function (DUF2512)
APOCAHHA_01784 1.6e-76 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
APOCAHHA_01785 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APOCAHHA_01786 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
APOCAHHA_01787 2.1e-109 yneB L resolvase
APOCAHHA_01788 1.3e-32 ynzC S UPF0291 protein
APOCAHHA_01789 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APOCAHHA_01790 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
APOCAHHA_01791 1.8e-28 yneF S UPF0154 protein
APOCAHHA_01792 1.2e-14 ynzD S Spo0E like sporulation regulatory protein
APOCAHHA_01793 6.9e-122 ccdA O cytochrome c biogenesis protein
APOCAHHA_01794 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
APOCAHHA_01795 2.5e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
APOCAHHA_01796 2.1e-73 yneK S Protein of unknown function (DUF2621)
APOCAHHA_01797 6.5e-63 hspX O Spore coat protein
APOCAHHA_01798 3.9e-19 sspP S Belongs to the SspP family
APOCAHHA_01799 2.5e-14 sspO S Belongs to the SspO family
APOCAHHA_01800 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
APOCAHHA_01801 6.1e-88 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APOCAHHA_01803 4e-08 sspN S Small acid-soluble spore protein N family
APOCAHHA_01804 6.6e-35 tlp S Belongs to the Tlp family
APOCAHHA_01805 2.4e-74 yneP S Thioesterase-like superfamily
APOCAHHA_01806 1.1e-52 yneQ
APOCAHHA_01807 1.2e-48 yneR S Belongs to the HesB IscA family
APOCAHHA_01808 1.1e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APOCAHHA_01810 3.3e-68 yccU S CoA-binding protein
APOCAHHA_01811 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APOCAHHA_01812 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APOCAHHA_01813 2.3e-12
APOCAHHA_01814 1.6e-55 ynfC
APOCAHHA_01815 2.7e-247 agcS E Sodium alanine symporter
APOCAHHA_01816 2.6e-261 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
APOCAHHA_01818 8.5e-248 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
APOCAHHA_01819 6.6e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
APOCAHHA_01820 1.1e-68 yngA S membrane
APOCAHHA_01821 2e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APOCAHHA_01822 5.5e-104 yngC S membrane-associated protein
APOCAHHA_01823 3.4e-230 nrnB S phosphohydrolase (DHH superfamily)
APOCAHHA_01824 4.6e-280 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APOCAHHA_01825 5.8e-130 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
APOCAHHA_01826 6.2e-160 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
APOCAHHA_01827 3.3e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
APOCAHHA_01828 9.6e-242 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
APOCAHHA_01829 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APOCAHHA_01830 6.3e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
APOCAHHA_01831 5.1e-19 2.3.1.128 J Acetyltransferase (GNAT) domain
APOCAHHA_01832 3.7e-298 yngK T Glycosyl hydrolase-like 10
APOCAHHA_01833 1.1e-63 yngL S Protein of unknown function (DUF1360)
APOCAHHA_01834 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
APOCAHHA_01835 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_01836 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_01837 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_01838 1.8e-293 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_01839 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_01840 1e-265 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
APOCAHHA_01841 4.2e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
APOCAHHA_01842 6.9e-243 yoeA V MATE efflux family protein
APOCAHHA_01843 2.4e-98 yoeB S IseA DL-endopeptidase inhibitor
APOCAHHA_01845 4.7e-94 L Integrase
APOCAHHA_01846 3e-34 yoeD G Helix-turn-helix domain
APOCAHHA_01847 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
APOCAHHA_01848 3.3e-147 gltR1 K Transcriptional regulator
APOCAHHA_01849 2.4e-173 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
APOCAHHA_01850 5.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
APOCAHHA_01851 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
APOCAHHA_01852 5.6e-153 gltC K Transcriptional regulator
APOCAHHA_01853 4.2e-198 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APOCAHHA_01854 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APOCAHHA_01855 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
APOCAHHA_01856 3.4e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_01857 9.1e-39 yoxC S Bacterial protein of unknown function (DUF948)
APOCAHHA_01858 4.8e-129 yoxB
APOCAHHA_01859 3.5e-86 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APOCAHHA_01860 2.9e-232 yoaB EGP Major facilitator Superfamily
APOCAHHA_01861 5.2e-265 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
APOCAHHA_01862 7.4e-178 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOCAHHA_01863 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOCAHHA_01864 2.5e-33 yoaF
APOCAHHA_01866 3.2e-07 ywlA S Uncharacterised protein family (UPF0715)
APOCAHHA_01867 2.5e-11
APOCAHHA_01868 1.9e-38 S Protein of unknown function (DUF4025)
APOCAHHA_01869 2.4e-173 mcpU NT methyl-accepting chemotaxis protein
APOCAHHA_01870 3.7e-271 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
APOCAHHA_01871 5.2e-130 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
APOCAHHA_01872 1.9e-108 yoaK S Membrane
APOCAHHA_01873 9.6e-68 pelB 4.2.2.10, 4.2.2.2 G Amb_all
APOCAHHA_01874 7.6e-110 yoqW S Belongs to the SOS response-associated peptidase family
APOCAHHA_01876 5.1e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
APOCAHHA_01878 3.8e-134 yoaP 3.1.3.18 K YoaP-like
APOCAHHA_01879 3.7e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
APOCAHHA_01880 8.9e-76
APOCAHHA_01881 3.4e-166 yoaR V vancomycin resistance protein
APOCAHHA_01882 3.8e-71 yoaS S Protein of unknown function (DUF2975)
APOCAHHA_01883 2.8e-29 yozG K Transcriptional regulator
APOCAHHA_01884 1.6e-140 yoaT S Protein of unknown function (DUF817)
APOCAHHA_01885 1.9e-153 yoaU K LysR substrate binding domain
APOCAHHA_01886 4.6e-152 yijE EG EamA-like transporter family
APOCAHHA_01887 3.6e-73 yoaW
APOCAHHA_01891 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
APOCAHHA_01892 1.9e-90 yokH G SMI1 / KNR4 family
APOCAHHA_01893 1.8e-262 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
APOCAHHA_01894 0.0 yobO M Pectate lyase superfamily protein
APOCAHHA_01895 1.7e-119 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
APOCAHHA_01896 5.4e-09 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
APOCAHHA_01897 3.8e-219 mleN_2 C antiporter
APOCAHHA_01903 4e-12 yoqW S Belongs to the SOS response-associated peptidase family
APOCAHHA_01904 5.7e-20 yokH G SMI1 / KNR4 family
APOCAHHA_01905 1.2e-18 yokH G SMI1 / KNR4 family
APOCAHHA_01906 1.3e-33
APOCAHHA_01907 5.4e-33
APOCAHHA_01909 1.2e-64 V ABC transporter
APOCAHHA_01910 3.9e-83
APOCAHHA_01914 4.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
APOCAHHA_01915 1.8e-59 ykvN K HxlR-like helix-turn-helix
APOCAHHA_01917 1.7e-51 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
APOCAHHA_01918 2.5e-135 yobQ K helix_turn_helix, arabinose operon control protein
APOCAHHA_01919 3.9e-136 yobR 2.3.1.1 J FR47-like protein
APOCAHHA_01920 5.8e-69 yobS K Transcriptional regulator
APOCAHHA_01921 1.7e-128 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
APOCAHHA_01922 3.6e-82 yobU K Bacterial transcription activator, effector binding domain
APOCAHHA_01923 2.2e-168 yobV K WYL domain
APOCAHHA_01924 2.5e-87 yobW
APOCAHHA_01925 1e-51 czrA K transcriptional
APOCAHHA_01926 2.4e-116 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APOCAHHA_01927 1.5e-92 yozB S membrane
APOCAHHA_01928 2.1e-135
APOCAHHA_01929 6.4e-90 yocC
APOCAHHA_01930 7.5e-43 yocD 3.4.17.13 V peptidase S66
APOCAHHA_01931 4.3e-132 yocD 3.4.17.13 V peptidase S66
APOCAHHA_01932 2.6e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
APOCAHHA_01933 1.5e-195 desK 2.7.13.3 T Histidine kinase
APOCAHHA_01934 1.6e-103 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_01935 3.2e-110 yocH CBM50 M COG1388 FOG LysM repeat
APOCAHHA_01936 0.0 recQ 3.6.4.12 L DNA helicase
APOCAHHA_01937 3.3e-112 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APOCAHHA_01938 5.9e-80 dksA T general stress protein
APOCAHHA_01939 1.1e-45 yocL
APOCAHHA_01940 5.8e-30
APOCAHHA_01941 4.1e-86 yocM O Belongs to the small heat shock protein (HSP20) family
APOCAHHA_01942 1.1e-40 yozN
APOCAHHA_01943 2.5e-36 yocN
APOCAHHA_01944 4.2e-56 yozO S Bacterial PH domain
APOCAHHA_01945 2.7e-31 yozC
APOCAHHA_01946 8.3e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
APOCAHHA_01947 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
APOCAHHA_01948 8.7e-164 sodA 1.15.1.1 P Superoxide dismutase
APOCAHHA_01949 3.1e-224 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APOCAHHA_01950 1.1e-162 yocS S -transporter
APOCAHHA_01951 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
APOCAHHA_01952 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
APOCAHHA_01953 0.0 yojO P Von Willebrand factor
APOCAHHA_01954 5.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
APOCAHHA_01955 1.2e-108 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
APOCAHHA_01956 2.4e-186 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
APOCAHHA_01957 8.5e-108 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
APOCAHHA_01958 5.4e-98 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
APOCAHHA_01959 2.1e-106 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APOCAHHA_01961 1.7e-241 norM V Multidrug efflux pump
APOCAHHA_01962 1.1e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APOCAHHA_01963 2.8e-125 yojG S deacetylase
APOCAHHA_01964 2.2e-60 yojF S Protein of unknown function (DUF1806)
APOCAHHA_01965 4.3e-43
APOCAHHA_01966 3e-162 rarD S -transporter
APOCAHHA_01967 3.3e-64 yozR S COG0071 Molecular chaperone (small heat shock protein)
APOCAHHA_01968 2.2e-08
APOCAHHA_01969 1.3e-61 yodA S tautomerase
APOCAHHA_01970 9.7e-55 yodB K transcriptional
APOCAHHA_01971 3.5e-106 yodC C nitroreductase
APOCAHHA_01972 8.7e-110 mhqD S Carboxylesterase
APOCAHHA_01973 6.2e-168 yodE E COG0346 Lactoylglutathione lyase and related lyases
APOCAHHA_01974 8.1e-28 S Protein of unknown function (DUF3311)
APOCAHHA_01975 3.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOCAHHA_01976 3.6e-247 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
APOCAHHA_01977 2e-126 yodH Q Methyltransferase
APOCAHHA_01978 4.4e-23 yodI
APOCAHHA_01979 1.2e-133 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
APOCAHHA_01980 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
APOCAHHA_01981 5.3e-09
APOCAHHA_01982 1e-53 yodL S YodL-like
APOCAHHA_01983 8.9e-102 yodM 3.6.1.27 I Acid phosphatase homologues
APOCAHHA_01984 2.8e-24 yozD S YozD-like protein
APOCAHHA_01986 3e-122 yodN
APOCAHHA_01987 3.1e-36 yozE S Belongs to the UPF0346 family
APOCAHHA_01988 3.2e-46 yokU S YokU-like protein, putative antitoxin
APOCAHHA_01989 1.1e-272 kamA 5.4.3.2 E lysine 2,3-aminomutase
APOCAHHA_01990 1.6e-146 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
APOCAHHA_01991 4.8e-254 yodQ 3.5.1.16 E Acetylornithine deacetylase
APOCAHHA_01992 3.2e-113 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APOCAHHA_01993 8.7e-122 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APOCAHHA_01994 6.2e-241 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOCAHHA_01995 1.2e-138 yiiD K acetyltransferase
APOCAHHA_01996 7e-242 cgeD M maturation of the outermost layer of the spore
APOCAHHA_01997 1.7e-37 cgeC
APOCAHHA_01998 3.7e-64 cgeA
APOCAHHA_01999 7e-178 cgeB S Spore maturation protein
APOCAHHA_02000 1.4e-204 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
APOCAHHA_02001 1.6e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
APOCAHHA_02002 4.1e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
APOCAHHA_02003 7.8e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APOCAHHA_02004 1.6e-70 ypoP K transcriptional
APOCAHHA_02005 2.3e-211 mepA V MATE efflux family protein
APOCAHHA_02006 2.1e-28 ypmT S Uncharacterized ympT
APOCAHHA_02007 9.4e-98 ypmS S protein conserved in bacteria
APOCAHHA_02008 6.5e-134 ypmR E GDSL-like Lipase/Acylhydrolase
APOCAHHA_02009 2.2e-102 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
APOCAHHA_02010 8.9e-40 ypmP S Protein of unknown function (DUF2535)
APOCAHHA_02011 7e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
APOCAHHA_02012 5.4e-173 pspF K Transcriptional regulator
APOCAHHA_02013 7.9e-109 hlyIII S protein, Hemolysin III
APOCAHHA_02014 3.7e-103 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APOCAHHA_02015 8.5e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APOCAHHA_02016 1.6e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
APOCAHHA_02017 7.8e-114 ypjP S YpjP-like protein
APOCAHHA_02018 2.1e-135 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
APOCAHHA_02019 1.7e-75 yphP S Belongs to the UPF0403 family
APOCAHHA_02020 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
APOCAHHA_02021 1.9e-153 ypgR C COG0694 Thioredoxin-like proteins and domains
APOCAHHA_02022 1.7e-105 ypgQ S phosphohydrolase
APOCAHHA_02023 1.4e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
APOCAHHA_02024 4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
APOCAHHA_02025 4.7e-213 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
APOCAHHA_02026 1e-30 cspD K Cold-shock protein
APOCAHHA_02027 1.7e-16 degR
APOCAHHA_02028 6.8e-30 S Protein of unknown function (DUF2564)
APOCAHHA_02029 1.7e-26 ypeQ S Zinc-finger
APOCAHHA_02030 4.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
APOCAHHA_02031 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
APOCAHHA_02032 1.3e-66 rnhA 3.1.26.4 L Ribonuclease
APOCAHHA_02034 3.7e-165 polA 2.7.7.7 L 5'3' exonuclease
APOCAHHA_02036 1.7e-07
APOCAHHA_02037 2.1e-36 ypbS S Protein of unknown function (DUF2533)
APOCAHHA_02038 0.0 ypbR S Dynamin family
APOCAHHA_02040 1.6e-85 ypbQ S protein conserved in bacteria
APOCAHHA_02041 1.4e-198 bcsA Q Naringenin-chalcone synthase
APOCAHHA_02042 2e-223 pbuX F xanthine
APOCAHHA_02043 2.6e-95 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APOCAHHA_02044 5.3e-289 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
APOCAHHA_02045 7.5e-133 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
APOCAHHA_02046 5.6e-101 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
APOCAHHA_02047 1.2e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
APOCAHHA_02048 7.9e-180 ptxS K transcriptional
APOCAHHA_02049 4.8e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
APOCAHHA_02050 1.5e-127 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_02051 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
APOCAHHA_02053 9.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
APOCAHHA_02054 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APOCAHHA_02055 7.2e-95 ypsA S Belongs to the UPF0398 family
APOCAHHA_02056 7.7e-35 cotD S Inner spore coat protein D
APOCAHHA_02057 2.1e-230 yprB L RNase_H superfamily
APOCAHHA_02058 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
APOCAHHA_02059 1e-83 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
APOCAHHA_02060 6.2e-70 hspX O Belongs to the small heat shock protein (HSP20) family
APOCAHHA_02061 1.3e-47 yppG S YppG-like protein
APOCAHHA_02063 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
APOCAHHA_02065 3.3e-183 yppC S Protein of unknown function (DUF2515)
APOCAHHA_02066 1.8e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APOCAHHA_02067 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
APOCAHHA_02068 1.2e-77 ypoC
APOCAHHA_02069 8.3e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APOCAHHA_02070 4.8e-128 dnaD L DNA replication protein DnaD
APOCAHHA_02071 2.2e-251 asnS 6.1.1.22 J asparaginyl-tRNA
APOCAHHA_02072 2.2e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
APOCAHHA_02073 4.2e-78 ypmB S protein conserved in bacteria
APOCAHHA_02074 6.7e-23 ypmA S Protein of unknown function (DUF4264)
APOCAHHA_02075 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
APOCAHHA_02076 1.8e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
APOCAHHA_02077 4.5e-152 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
APOCAHHA_02078 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
APOCAHHA_02079 4.2e-178 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APOCAHHA_02080 2.1e-211 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APOCAHHA_02081 3.8e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
APOCAHHA_02082 3.5e-126 bshB1 S proteins, LmbE homologs
APOCAHHA_02083 2.7e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
APOCAHHA_02084 2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APOCAHHA_02085 2e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
APOCAHHA_02086 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
APOCAHHA_02087 1.4e-136 ypjB S sporulation protein
APOCAHHA_02088 4.8e-94 ypjA S membrane
APOCAHHA_02089 8.2e-145 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
APOCAHHA_02090 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
APOCAHHA_02091 2.1e-96 qcrA C Menaquinol-cytochrome c reductase
APOCAHHA_02092 5.7e-74 ypiF S Protein of unknown function (DUF2487)
APOCAHHA_02093 6.2e-99 ypiB S Belongs to the UPF0302 family
APOCAHHA_02094 2.3e-229 S COG0457 FOG TPR repeat
APOCAHHA_02095 1.1e-229 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APOCAHHA_02096 7.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
APOCAHHA_02097 6.4e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APOCAHHA_02098 2.7e-138 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
APOCAHHA_02099 2.1e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APOCAHHA_02100 2.2e-106 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
APOCAHHA_02101 1.5e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
APOCAHHA_02102 1.1e-176 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APOCAHHA_02103 1.4e-284 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APOCAHHA_02104 3.3e-62 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
APOCAHHA_02105 7.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
APOCAHHA_02106 2.1e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APOCAHHA_02107 1.7e-137 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
APOCAHHA_02108 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
APOCAHHA_02109 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APOCAHHA_02110 8e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APOCAHHA_02111 4.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
APOCAHHA_02112 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
APOCAHHA_02113 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
APOCAHHA_02114 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APOCAHHA_02115 1.4e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
APOCAHHA_02116 2.6e-132 yphF
APOCAHHA_02117 1.6e-18 yphE S Protein of unknown function (DUF2768)
APOCAHHA_02118 2.5e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
APOCAHHA_02119 8.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
APOCAHHA_02120 4.6e-28 ypzH
APOCAHHA_02121 1.2e-160 seaA S YIEGIA protein
APOCAHHA_02122 5e-97 yphA
APOCAHHA_02123 1e-07 S YpzI-like protein
APOCAHHA_02124 2.1e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APOCAHHA_02125 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
APOCAHHA_02126 1.2e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
APOCAHHA_02127 6.9e-23 S Family of unknown function (DUF5359)
APOCAHHA_02128 3.5e-104 ypfA M Flagellar protein YcgR
APOCAHHA_02129 7.9e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
APOCAHHA_02130 9.7e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
APOCAHHA_02131 2.5e-118 prsW S Involved in the degradation of specific anti-sigma factors
APOCAHHA_02132 4.3e-175 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
APOCAHHA_02133 2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
APOCAHHA_02134 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APOCAHHA_02135 1.2e-140 ypbG S Calcineurin-like phosphoesterase superfamily domain
APOCAHHA_02136 9.4e-77 ypbF S Protein of unknown function (DUF2663)
APOCAHHA_02137 2.1e-68 ypbE M Lysin motif
APOCAHHA_02138 1.1e-96 ypbD S metal-dependent membrane protease
APOCAHHA_02139 4e-273 recQ 3.6.4.12 L DNA helicase
APOCAHHA_02140 6.1e-191 ypbB 5.1.3.1 S protein conserved in bacteria
APOCAHHA_02141 4.7e-41 fer C Ferredoxin
APOCAHHA_02142 2.7e-84 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APOCAHHA_02143 9.2e-10
APOCAHHA_02144 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOCAHHA_02145 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
APOCAHHA_02146 3.9e-188 rsiX
APOCAHHA_02147 2.9e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_02148 0.0 resE 2.7.13.3 T Histidine kinase
APOCAHHA_02149 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_02150 9.1e-212 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
APOCAHHA_02151 1.7e-309 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
APOCAHHA_02152 5.3e-98 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
APOCAHHA_02153 2.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APOCAHHA_02154 7.1e-87 spmB S Spore maturation protein
APOCAHHA_02155 1e-102 spmA S Spore maturation protein
APOCAHHA_02156 1.6e-208 dacB 3.4.16.4 M Belongs to the peptidase S11 family
APOCAHHA_02157 1.7e-96 ypuI S Protein of unknown function (DUF3907)
APOCAHHA_02158 7.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APOCAHHA_02159 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APOCAHHA_02160 6.1e-83 ypuF S Domain of unknown function (DUF309)
APOCAHHA_02161 6.5e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOCAHHA_02162 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APOCAHHA_02163 4.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APOCAHHA_02164 6.3e-114 ribE 2.5.1.9 H Riboflavin synthase
APOCAHHA_02165 2.5e-200 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APOCAHHA_02166 3.9e-54 ypuD
APOCAHHA_02167 2.6e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
APOCAHHA_02168 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
APOCAHHA_02169 3.6e-116 S SNARE associated Golgi protein
APOCAHHA_02171 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APOCAHHA_02172 1.3e-149 ypuA S Secreted protein
APOCAHHA_02173 2.8e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APOCAHHA_02174 2.9e-271 spoVAF EG Stage V sporulation protein AF
APOCAHHA_02175 5.2e-110 spoVAEA S stage V sporulation protein
APOCAHHA_02176 5e-57 spoVAEB S stage V sporulation protein
APOCAHHA_02177 5e-190 spoVAD I Stage V sporulation protein AD
APOCAHHA_02178 2.3e-78 spoVAC S stage V sporulation protein AC
APOCAHHA_02179 1e-67 spoVAB S Stage V sporulation protein AB
APOCAHHA_02180 5.3e-110 spoVAA S Stage V sporulation protein AA
APOCAHHA_02181 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOCAHHA_02182 1.5e-74 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
APOCAHHA_02183 3.3e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
APOCAHHA_02184 4.5e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
APOCAHHA_02185 8.4e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
APOCAHHA_02186 7.5e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
APOCAHHA_02187 7.5e-166 xerD L recombinase XerD
APOCAHHA_02188 1.1e-36 S Protein of unknown function (DUF4227)
APOCAHHA_02189 2.4e-80 fur P Belongs to the Fur family
APOCAHHA_02190 1.1e-105 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
APOCAHHA_02191 5.3e-25 yqkK
APOCAHHA_02192 2e-239 mleA 1.1.1.38 C malic enzyme
APOCAHHA_02193 4.3e-224 mleN C Na H antiporter
APOCAHHA_02194 5.4e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
APOCAHHA_02195 4.4e-183 ansA 3.5.1.1 EJ L-asparaginase
APOCAHHA_02196 6.5e-57 ansR K Transcriptional regulator
APOCAHHA_02197 5.1e-215 yqxK 3.6.4.12 L DNA helicase
APOCAHHA_02198 3.8e-91 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
APOCAHHA_02200 1.5e-164 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
APOCAHHA_02201 7e-12 yqkE S Protein of unknown function (DUF3886)
APOCAHHA_02202 5.7e-161 yqkD S COG1073 Hydrolases of the alpha beta superfamily
APOCAHHA_02203 3.9e-37 yqkC S Protein of unknown function (DUF2552)
APOCAHHA_02204 6.9e-53 yqkB S Belongs to the HesB IscA family
APOCAHHA_02205 1.1e-181 yqkA K GrpB protein
APOCAHHA_02206 3e-54 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
APOCAHHA_02207 5.3e-86 yqjY K acetyltransferase
APOCAHHA_02208 1.5e-50 S YolD-like protein
APOCAHHA_02209 4.6e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APOCAHHA_02211 4.3e-212 yqjV G Major Facilitator Superfamily
APOCAHHA_02213 1.2e-08 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOCAHHA_02214 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
APOCAHHA_02215 1.2e-197 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
APOCAHHA_02216 3.9e-22 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
APOCAHHA_02217 1.2e-140 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_02218 8e-174 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
APOCAHHA_02219 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APOCAHHA_02220 2.3e-298 rocB E arginine degradation protein
APOCAHHA_02221 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
APOCAHHA_02222 2.4e-141 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APOCAHHA_02223 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APOCAHHA_02224 6.3e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APOCAHHA_02225 6.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APOCAHHA_02226 2e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APOCAHHA_02227 3.2e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APOCAHHA_02228 1.6e-24 yqzJ
APOCAHHA_02229 2.7e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APOCAHHA_02230 2.2e-131 yqjF S Uncharacterized conserved protein (COG2071)
APOCAHHA_02231 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
APOCAHHA_02232 5.7e-283 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APOCAHHA_02233 3.1e-69 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
APOCAHHA_02235 1.8e-98 yqjB S protein conserved in bacteria
APOCAHHA_02236 2.8e-174 yqjA S Putative aromatic acid exporter C-terminal domain
APOCAHHA_02237 2.9e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APOCAHHA_02238 4e-108 artQ E COG0765 ABC-type amino acid transport system, permease component
APOCAHHA_02239 7.9e-132 artP ET Belongs to the bacterial solute-binding protein 3 family
APOCAHHA_02240 6e-76 yqiW S Belongs to the UPF0403 family
APOCAHHA_02241 5.4e-164 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APOCAHHA_02242 1.3e-205 norA EGP Major facilitator Superfamily
APOCAHHA_02243 2.4e-150 bmrR K helix_turn_helix, mercury resistance
APOCAHHA_02244 1.6e-217 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APOCAHHA_02245 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APOCAHHA_02246 2.3e-184 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APOCAHHA_02247 1.3e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APOCAHHA_02248 8.7e-201 buk 2.7.2.7 C Belongs to the acetokinase family
APOCAHHA_02249 4.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
APOCAHHA_02250 6.6e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
APOCAHHA_02251 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
APOCAHHA_02252 2e-33 yqzF S Protein of unknown function (DUF2627)
APOCAHHA_02253 2.7e-155 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
APOCAHHA_02254 5.3e-267 prpD 4.2.1.79 S 2-methylcitrate dehydratase
APOCAHHA_02255 1.3e-202 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
APOCAHHA_02256 1e-204 mmgC I acyl-CoA dehydrogenase
APOCAHHA_02257 2.1e-149 hbdA 1.1.1.157 I Dehydrogenase
APOCAHHA_02258 4.4e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
APOCAHHA_02259 1.4e-122 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APOCAHHA_02260 3.3e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
APOCAHHA_02261 3.5e-27
APOCAHHA_02262 1.2e-211 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
APOCAHHA_02265 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
APOCAHHA_02266 3.4e-236 rseP 3.4.21.116 M Stage IV sporulation protein B
APOCAHHA_02267 1.1e-287 recN L May be involved in recombinational repair of damaged DNA
APOCAHHA_02268 1.7e-78 argR K Regulates arginine biosynthesis genes
APOCAHHA_02269 1.4e-153 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
APOCAHHA_02270 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APOCAHHA_02271 4.7e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APOCAHHA_02272 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APOCAHHA_02273 1.6e-241 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APOCAHHA_02274 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APOCAHHA_02275 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APOCAHHA_02276 2.4e-66 yqhY S protein conserved in bacteria
APOCAHHA_02277 1.3e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
APOCAHHA_02278 1.4e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APOCAHHA_02279 9.9e-91 spoIIIAH S SpoIIIAH-like protein
APOCAHHA_02280 1.7e-109 spoIIIAG S stage III sporulation protein AG
APOCAHHA_02281 3.2e-99 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
APOCAHHA_02282 2.4e-196 spoIIIAE S stage III sporulation protein AE
APOCAHHA_02283 2.3e-58 spoIIIAD S Stage III sporulation protein AD
APOCAHHA_02284 7.6e-29 spoIIIAC S stage III sporulation protein AC
APOCAHHA_02285 3.6e-80 spoIIIAB S Stage III sporulation protein
APOCAHHA_02286 4.1e-167 spoIIIAA S stage III sporulation protein AA
APOCAHHA_02287 4.6e-37 yqhV S Protein of unknown function (DUF2619)
APOCAHHA_02288 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APOCAHHA_02289 1.6e-170 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
APOCAHHA_02290 4.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
APOCAHHA_02291 1.5e-92 yqhR S Conserved membrane protein YqhR
APOCAHHA_02292 1.2e-169 yqhQ S Protein of unknown function (DUF1385)
APOCAHHA_02293 2.9e-61 yqhP
APOCAHHA_02294 9e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
APOCAHHA_02295 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
APOCAHHA_02296 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
APOCAHHA_02297 1.1e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
APOCAHHA_02298 8e-282 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APOCAHHA_02299 9e-248 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APOCAHHA_02300 7.9e-202 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
APOCAHHA_02301 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
APOCAHHA_02302 6e-151 yqhG S Bacterial protein YqhG of unknown function
APOCAHHA_02303 1.2e-24 sinI S Anti-repressor SinI
APOCAHHA_02304 1e-54 sinR K transcriptional
APOCAHHA_02305 2.5e-141 tasA S Cell division protein FtsN
APOCAHHA_02306 1.1e-56 sipW 3.4.21.89 U Signal peptidase
APOCAHHA_02307 1.6e-97 yqxM
APOCAHHA_02308 1.3e-51 yqzG S Protein of unknown function (DUF3889)
APOCAHHA_02309 5.2e-26 yqzE S YqzE-like protein
APOCAHHA_02310 3.2e-46 S ComG operon protein 7
APOCAHHA_02311 2.1e-42 comGF U Putative Competence protein ComGF
APOCAHHA_02312 3.3e-53 comGE
APOCAHHA_02313 2.9e-62 gspH NU protein transport across the cell outer membrane
APOCAHHA_02314 2e-46 comGC U Required for transformation and DNA binding
APOCAHHA_02315 9.6e-165 comGB NU COG1459 Type II secretory pathway, component PulF
APOCAHHA_02316 9.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APOCAHHA_02317 2.6e-49 ylbB S Cbs domain
APOCAHHA_02318 1.8e-170 corA P Mg2 transporter protein
APOCAHHA_02319 2.2e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
APOCAHHA_02320 1.9e-142 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APOCAHHA_02322 3e-63 yqgZ 1.20.4.1 P Belongs to the ArsC family
APOCAHHA_02323 5.3e-37 yqgY S Protein of unknown function (DUF2626)
APOCAHHA_02324 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
APOCAHHA_02325 8.9e-23 yqgW S Protein of unknown function (DUF2759)
APOCAHHA_02326 2e-49 yqgV S Thiamine-binding protein
APOCAHHA_02327 6.7e-190 yqgU
APOCAHHA_02328 2.7e-213 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
APOCAHHA_02329 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APOCAHHA_02330 2e-180 glcK 2.7.1.2 G Glucokinase
APOCAHHA_02331 1.3e-28 yqgQ S Protein conserved in bacteria
APOCAHHA_02332 6.6e-223 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
APOCAHHA_02333 2.5e-09 yqgO
APOCAHHA_02334 5.5e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APOCAHHA_02335 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APOCAHHA_02336 1.3e-185 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
APOCAHHA_02338 3.5e-50 yqzD
APOCAHHA_02339 1.5e-72 yqzC S YceG-like family
APOCAHHA_02340 1e-142 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APOCAHHA_02341 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APOCAHHA_02342 6.3e-157 pstA P Phosphate transport system permease
APOCAHHA_02343 2.7e-158 pstC P probably responsible for the translocation of the substrate across the membrane
APOCAHHA_02344 5.4e-148 pstS P Phosphate
APOCAHHA_02345 0.0 pbpA 3.4.16.4 M penicillin-binding protein
APOCAHHA_02346 3.3e-231 yqgE EGP Major facilitator superfamily
APOCAHHA_02347 9.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
APOCAHHA_02348 5.2e-73 yqgC S protein conserved in bacteria
APOCAHHA_02349 5.6e-130 yqgB S Protein of unknown function (DUF1189)
APOCAHHA_02350 5.8e-46 yqfZ M LysM domain
APOCAHHA_02351 2.4e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
APOCAHHA_02352 3e-55 yqfX S membrane
APOCAHHA_02353 4.6e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
APOCAHHA_02354 1.9e-77 zur P Belongs to the Fur family
APOCAHHA_02355 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
APOCAHHA_02356 8.7e-35 yqfT S Protein of unknown function (DUF2624)
APOCAHHA_02357 4.8e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
APOCAHHA_02358 9.4e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APOCAHHA_02359 9e-08 yqfQ S YqfQ-like protein
APOCAHHA_02360 1.6e-174 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
APOCAHHA_02361 9e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APOCAHHA_02362 1.2e-112 trmK 2.1.1.217 S SAM-dependent methyltransferase
APOCAHHA_02363 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
APOCAHHA_02364 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APOCAHHA_02365 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APOCAHHA_02366 2.5e-86 yaiI S Belongs to the UPF0178 family
APOCAHHA_02367 7.6e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
APOCAHHA_02368 4.5e-112 ccpN K CBS domain
APOCAHHA_02369 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
APOCAHHA_02370 7.4e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
APOCAHHA_02371 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
APOCAHHA_02372 8.4e-19 S YqzL-like protein
APOCAHHA_02373 1.2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APOCAHHA_02374 9.3e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
APOCAHHA_02375 3.1e-57 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
APOCAHHA_02376 1.3e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APOCAHHA_02377 2.7e-304 yqfF S membrane-associated HD superfamily hydrolase
APOCAHHA_02379 1.2e-174 phoH T Phosphate starvation-inducible protein PhoH
APOCAHHA_02380 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
APOCAHHA_02381 4.6e-45 yqfC S sporulation protein YqfC
APOCAHHA_02382 8.1e-30 yqfB
APOCAHHA_02383 1.1e-120 yqfA S UPF0365 protein
APOCAHHA_02384 2.8e-209 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
APOCAHHA_02385 2.3e-62 yqeY S Yqey-like protein
APOCAHHA_02386 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
APOCAHHA_02387 3.9e-157 yqeW P COG1283 Na phosphate symporter
APOCAHHA_02388 3e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
APOCAHHA_02389 3.3e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APOCAHHA_02390 4.6e-174 prmA J Methylates ribosomal protein L11
APOCAHHA_02391 1.5e-179 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APOCAHHA_02392 0.0 dnaK O Heat shock 70 kDa protein
APOCAHHA_02393 1.5e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APOCAHHA_02394 1e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APOCAHHA_02395 1.6e-213 hemN H Involved in the biosynthesis of porphyrin-containing compound
APOCAHHA_02396 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APOCAHHA_02397 1e-51 yqxA S Protein of unknown function (DUF3679)
APOCAHHA_02398 6e-219 spoIIP M stage II sporulation protein P
APOCAHHA_02399 2.8e-202 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
APOCAHHA_02400 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
APOCAHHA_02401 2.1e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
APOCAHHA_02402 4.1e-15 S YqzM-like protein
APOCAHHA_02403 0.0 comEC S Competence protein ComEC
APOCAHHA_02404 1e-104 comEB 3.5.4.12 F ComE operon protein 2
APOCAHHA_02405 1.6e-95 wza L COG1555 DNA uptake protein and related DNA-binding proteins
APOCAHHA_02406 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APOCAHHA_02407 2.2e-134 yqeM Q Methyltransferase
APOCAHHA_02408 2.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APOCAHHA_02409 1.4e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
APOCAHHA_02410 1e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APOCAHHA_02411 3.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
APOCAHHA_02412 4.7e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APOCAHHA_02413 1.7e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
APOCAHHA_02414 5.3e-95 yqeG S hydrolase of the HAD superfamily
APOCAHHA_02416 1.9e-138 yqeF E GDSL-like Lipase/Acylhydrolase
APOCAHHA_02417 6e-08 yqeD S SNARE associated Golgi protein
APOCAHHA_02418 1e-82 yqeD S SNARE associated Golgi protein
APOCAHHA_02420 5.6e-122 yqeB
APOCAHHA_02421 1.1e-71 nucB M Deoxyribonuclease NucA/NucB
APOCAHHA_02422 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APOCAHHA_02423 5.8e-258 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APOCAHHA_02424 1.5e-153 K Transcriptional regulator
APOCAHHA_02425 1.6e-160 ydhE CG UDP-glucoronosyl and UDP-glucosyl transferase
APOCAHHA_02426 5.5e-72 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
APOCAHHA_02427 1.6e-205 EGP Major Facilitator Superfamily
APOCAHHA_02428 2.1e-78 P Major Facilitator Superfamily
APOCAHHA_02429 4.5e-170 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOCAHHA_02430 7.2e-58 mdaB S Flavodoxin-like fold
APOCAHHA_02431 2.3e-79 yvbU K Transcriptional regulator
APOCAHHA_02432 4e-177 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
APOCAHHA_02435 5.4e-129 S Aspartate phosphatase response regulator
APOCAHHA_02436 1.2e-225 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APOCAHHA_02437 7.4e-25 yokK S SMI1 / KNR4 family
APOCAHHA_02438 2.2e-30 S SMI1 / KNR4 family
APOCAHHA_02439 2.2e-47
APOCAHHA_02440 1.4e-40
APOCAHHA_02442 1e-101 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
APOCAHHA_02444 7.7e-77 yqaS L DNA packaging
APOCAHHA_02445 6e-47
APOCAHHA_02447 4.6e-42 L Transposase
APOCAHHA_02449 3.6e-31 yqaO S Phage-like element PBSX protein XtrA
APOCAHHA_02450 1.4e-25 rusA L Endodeoxyribonuclease RusA
APOCAHHA_02453 2.9e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
APOCAHHA_02454 6.1e-91 K Transcriptional regulator PadR-like family
APOCAHHA_02455 1.9e-100 adk 2.7.4.3 F adenylate kinase activity
APOCAHHA_02456 7.3e-15 yqaB E IrrE N-terminal-like domain
APOCAHHA_02457 3.5e-77 S Protein of unknown function with HXXEE motif
APOCAHHA_02458 9.2e-112 yrkJ S membrane transporter protein
APOCAHHA_02459 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
APOCAHHA_02460 9.3e-198 yrkH P Rhodanese Homology Domain
APOCAHHA_02461 9.7e-80 yrkF OP Belongs to the sulfur carrier protein TusA family
APOCAHHA_02462 1.1e-49 P Rhodanese Homology Domain
APOCAHHA_02463 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
APOCAHHA_02464 7.8e-39 yrkD S protein conserved in bacteria
APOCAHHA_02465 1.8e-104 yrkC G Cupin domain
APOCAHHA_02466 1.9e-144 bltR K helix_turn_helix, mercury resistance
APOCAHHA_02467 2.5e-204 blt EGP Major facilitator Superfamily
APOCAHHA_02468 7.9e-79 bltD 2.3.1.57 K FR47-like protein
APOCAHHA_02469 1.4e-78 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
APOCAHHA_02470 7.1e-142 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
APOCAHHA_02471 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
APOCAHHA_02472 3.2e-83 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
APOCAHHA_02473 1.9e-168 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
APOCAHHA_02474 8.8e-139 S Fusaric acid resistance protein-like
APOCAHHA_02475 1e-151 eaeH M Domain of Unknown Function (DUF1259)
APOCAHHA_02477 1.7e-182 trkA P Oxidoreductase
APOCAHHA_02478 4.3e-148 czcD P COG1230 Co Zn Cd efflux system component
APOCAHHA_02479 2.6e-164 scrR K transcriptional
APOCAHHA_02480 5.1e-224 msmE G Bacterial extracellular solute-binding protein
APOCAHHA_02481 4.8e-147 msmF P Binding-protein-dependent transport system inner membrane component
APOCAHHA_02482 3.5e-141 msmG P PFAM binding-protein-dependent transport systems inner membrane component
APOCAHHA_02483 2.7e-198 rafB P LacY proton/sugar symporter
APOCAHHA_02484 1.7e-247 cscA 3.2.1.26 GH32 G invertase
APOCAHHA_02485 1.1e-93 yrdC 3.5.1.19 Q Isochorismatase family
APOCAHHA_02486 3.7e-53 S Protein of unknown function (DUF2568)
APOCAHHA_02488 9.3e-89 yrdA S DinB family
APOCAHHA_02489 2.2e-159 aadK G Streptomycin adenylyltransferase
APOCAHHA_02490 3.4e-147 gltR K LysR substrate binding domain
APOCAHHA_02491 4.6e-183 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
APOCAHHA_02492 5.8e-127 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APOCAHHA_02493 1.5e-121 yrpD S Domain of unknown function, YrpD
APOCAHHA_02494 1.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
APOCAHHA_02496 3e-211 rbtT P Major Facilitator Superfamily
APOCAHHA_02497 2.4e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_02498 5.9e-153 2.2.1.1 G Transketolase, pyrimidine binding domain
APOCAHHA_02499 1.8e-137 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
APOCAHHA_02501 1.2e-213 yfjF U Belongs to the major facilitator superfamily
APOCAHHA_02502 1.8e-65 napB K MarR family transcriptional regulator
APOCAHHA_02503 7.1e-109 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
APOCAHHA_02504 3.3e-147 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
APOCAHHA_02505 1.2e-39 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_02506 9.3e-139 S Alpha beta hydrolase
APOCAHHA_02507 2.2e-60 T sh3 domain protein
APOCAHHA_02508 1.4e-59 T sh3 domain protein
APOCAHHA_02509 2.3e-63 E Glyoxalase-like domain
APOCAHHA_02510 1.3e-35 yraG
APOCAHHA_02511 4.2e-62 yraF M Spore coat protein
APOCAHHA_02512 3.3e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APOCAHHA_02513 4.1e-25 yraE
APOCAHHA_02514 4.7e-48 yraD M Spore coat protein
APOCAHHA_02515 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
APOCAHHA_02516 1.7e-151 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
APOCAHHA_02517 1.2e-114 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
APOCAHHA_02518 9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
APOCAHHA_02519 2.8e-73 levD 2.7.1.202 G PTS system fructose IIA component
APOCAHHA_02520 0.0 levR K PTS system fructose IIA component
APOCAHHA_02521 9.6e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
APOCAHHA_02522 1.5e-104 yrhP E LysE type translocator
APOCAHHA_02523 2e-149 yrhO K Archaeal transcriptional regulator TrmB
APOCAHHA_02524 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_02525 1.2e-147 rsiV S Protein of unknown function (DUF3298)
APOCAHHA_02526 0.0 yrhL I Acyltransferase family
APOCAHHA_02527 2.4e-44 yrhK S YrhK-like protein
APOCAHHA_02528 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
APOCAHHA_02529 8.5e-102 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
APOCAHHA_02530 3.2e-87 yrhH Q methyltransferase
APOCAHHA_02533 5.7e-141 focA P Formate nitrite
APOCAHHA_02534 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
APOCAHHA_02535 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
APOCAHHA_02536 2.1e-77 yrhD S Protein of unknown function (DUF1641)
APOCAHHA_02537 4.6e-35 yrhC S YrhC-like protein
APOCAHHA_02538 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APOCAHHA_02539 5.4e-167 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
APOCAHHA_02540 1.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APOCAHHA_02541 3.9e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
APOCAHHA_02542 1e-25 yrzA S Protein of unknown function (DUF2536)
APOCAHHA_02543 5.6e-60 yrrS S Protein of unknown function (DUF1510)
APOCAHHA_02544 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
APOCAHHA_02545 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APOCAHHA_02546 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
APOCAHHA_02547 3.6e-246 yegQ O COG0826 Collagenase and related proteases
APOCAHHA_02548 4.3e-172 yegQ O Peptidase U32
APOCAHHA_02549 2.5e-118 yrrM 2.1.1.104 S O-methyltransferase
APOCAHHA_02550 4e-182 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APOCAHHA_02551 4.6e-45 yrzB S Belongs to the UPF0473 family
APOCAHHA_02552 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APOCAHHA_02553 1.7e-41 yrzL S Belongs to the UPF0297 family
APOCAHHA_02554 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APOCAHHA_02555 2.1e-167 yrrI S AI-2E family transporter
APOCAHHA_02556 1e-07 S Protein of unknown function (DUF3918)
APOCAHHA_02557 9.8e-31 yrzR
APOCAHHA_02558 3.9e-81 yrrD S protein conserved in bacteria
APOCAHHA_02559 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APOCAHHA_02560 1.4e-15 S COG0457 FOG TPR repeat
APOCAHHA_02561 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APOCAHHA_02562 1.1e-201 iscS 2.8.1.7 E Cysteine desulfurase
APOCAHHA_02563 1.2e-70 cymR K Transcriptional regulator
APOCAHHA_02564 3.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
APOCAHHA_02565 1.7e-134 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
APOCAHHA_02566 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
APOCAHHA_02567 6.3e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
APOCAHHA_02569 8.8e-255 lytH 3.5.1.28 M COG3103 SH3 domain protein
APOCAHHA_02570 4.5e-71 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APOCAHHA_02571 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APOCAHHA_02572 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APOCAHHA_02573 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
APOCAHHA_02574 1.9e-47 yrvD S Lipopolysaccharide assembly protein A domain
APOCAHHA_02575 1.2e-80 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
APOCAHHA_02576 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APOCAHHA_02577 1.4e-47 yrzD S Post-transcriptional regulator
APOCAHHA_02578 7.2e-265 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOCAHHA_02579 2.7e-88 yrbG S membrane
APOCAHHA_02580 1.3e-73 yrzE S Protein of unknown function (DUF3792)
APOCAHHA_02581 3e-38 yajC U Preprotein translocase subunit YajC
APOCAHHA_02582 9.7e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APOCAHHA_02583 1.3e-193 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APOCAHHA_02584 1.3e-17 yrzS S Protein of unknown function (DUF2905)
APOCAHHA_02585 3.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APOCAHHA_02586 4.5e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APOCAHHA_02587 1.1e-89 bofC S BofC C-terminal domain
APOCAHHA_02588 7.4e-247 csbX EGP Major facilitator Superfamily
APOCAHHA_02589 1.2e-188 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
APOCAHHA_02590 1.4e-116 yrzF T serine threonine protein kinase
APOCAHHA_02592 4.9e-51 S Family of unknown function (DUF5412)
APOCAHHA_02593 4.8e-255 alsT E Sodium alanine symporter
APOCAHHA_02594 5.9e-86 yebC K transcriptional regulatory protein
APOCAHHA_02595 2e-53 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APOCAHHA_02596 2.2e-146 safA M spore coat assembly protein SafA
APOCAHHA_02597 2.3e-209 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
APOCAHHA_02598 4.7e-149 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
APOCAHHA_02599 4.3e-289 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
APOCAHHA_02600 1e-215 nifS 2.8.1.7 E Cysteine desulfurase
APOCAHHA_02601 8.2e-91 niaR S small molecule binding protein (contains 3H domain)
APOCAHHA_02602 4.9e-162 pheA 4.2.1.51 E Prephenate dehydratase
APOCAHHA_02603 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
APOCAHHA_02604 3.3e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APOCAHHA_02605 9e-104 spo0B T Sporulation initiation phospho-transferase B, C-terminal
APOCAHHA_02606 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
APOCAHHA_02607 7e-56 ysxB J ribosomal protein
APOCAHHA_02608 2.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
APOCAHHA_02609 5e-159 spoIVFB S Stage IV sporulation protein
APOCAHHA_02610 1.1e-141 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
APOCAHHA_02611 4.7e-143 minD D Belongs to the ParA family
APOCAHHA_02612 8.1e-112 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
APOCAHHA_02613 7.1e-84 mreD M shape-determining protein
APOCAHHA_02614 8.9e-156 mreC M Involved in formation and maintenance of cell shape
APOCAHHA_02615 1.8e-184 mreB D Rod shape-determining protein MreB
APOCAHHA_02616 1.5e-124 radC E Belongs to the UPF0758 family
APOCAHHA_02617 7.8e-100 maf D septum formation protein Maf
APOCAHHA_02618 4.9e-158 spoIIB S Sporulation related domain
APOCAHHA_02619 4.9e-80 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
APOCAHHA_02620 1.5e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APOCAHHA_02621 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APOCAHHA_02622 1.6e-25
APOCAHHA_02623 1.1e-192 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
APOCAHHA_02624 1.6e-188 spoVID M stage VI sporulation protein D
APOCAHHA_02625 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
APOCAHHA_02626 9e-181 hemB 4.2.1.24 H Belongs to the ALAD family
APOCAHHA_02627 1.7e-137 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APOCAHHA_02628 3.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
APOCAHHA_02629 1.4e-145 hemX O cytochrome C
APOCAHHA_02630 2.9e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
APOCAHHA_02631 3.5e-88 ysxD
APOCAHHA_02632 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
APOCAHHA_02633 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
APOCAHHA_02634 6.6e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
APOCAHHA_02635 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APOCAHHA_02636 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APOCAHHA_02637 2.8e-185 ysoA H Tetratricopeptide repeat
APOCAHHA_02638 9.9e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APOCAHHA_02639 5.3e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APOCAHHA_02640 2.6e-197 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
APOCAHHA_02641 3.5e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
APOCAHHA_02642 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
APOCAHHA_02643 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
APOCAHHA_02644 0.0 ilvB 2.2.1.6 E Acetolactate synthase
APOCAHHA_02646 6.8e-78 ysnE K acetyltransferase
APOCAHHA_02647 1.2e-125 ysnF S protein conserved in bacteria
APOCAHHA_02649 1.2e-91 ysnB S Phosphoesterase
APOCAHHA_02650 3.8e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APOCAHHA_02651 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
APOCAHHA_02652 3.1e-190 gerM S COG5401 Spore germination protein
APOCAHHA_02653 1.7e-153 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APOCAHHA_02654 8.7e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
APOCAHHA_02655 3.3e-30 gerE K Transcriptional regulator
APOCAHHA_02656 3.3e-74 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
APOCAHHA_02657 3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
APOCAHHA_02658 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
APOCAHHA_02659 2.4e-107 sdhC C succinate dehydrogenase
APOCAHHA_02660 1.2e-79 yslB S Protein of unknown function (DUF2507)
APOCAHHA_02661 3.5e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
APOCAHHA_02662 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APOCAHHA_02663 2.5e-52 trxA O Belongs to the thioredoxin family
APOCAHHA_02664 8.9e-297 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
APOCAHHA_02666 1.1e-173 etfA C Electron transfer flavoprotein
APOCAHHA_02667 1.9e-133 etfB C Electron transfer flavoprotein
APOCAHHA_02668 3.8e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
APOCAHHA_02669 6.7e-99 fadR K Transcriptional regulator
APOCAHHA_02670 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APOCAHHA_02671 4.7e-67 yshE S membrane
APOCAHHA_02672 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APOCAHHA_02673 0.0 polX L COG1796 DNA polymerase IV (family X)
APOCAHHA_02674 1.6e-83 cvpA S membrane protein, required for colicin V production
APOCAHHA_02675 5.3e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APOCAHHA_02676 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APOCAHHA_02677 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APOCAHHA_02678 3.1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APOCAHHA_02679 6.8e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APOCAHHA_02680 4.5e-32 sspI S Belongs to the SspI family
APOCAHHA_02681 1.7e-191 ysfB KT regulator
APOCAHHA_02682 5.2e-254 glcD 1.1.3.15 C Glycolate oxidase subunit
APOCAHHA_02683 4.3e-250 glcF C Glycolate oxidase
APOCAHHA_02684 1.4e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
APOCAHHA_02685 0.0 cstA T Carbon starvation protein
APOCAHHA_02686 7.6e-78 S Putative adhesin
APOCAHHA_02687 2.4e-82 S Protein of unknown function (DUF1700)
APOCAHHA_02688 1.7e-54 K PadR family transcriptional regulator
APOCAHHA_02689 1.9e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
APOCAHHA_02690 2.3e-140 araQ G transport system permease
APOCAHHA_02691 2.7e-166 araP G carbohydrate transport
APOCAHHA_02692 9e-253 araN G carbohydrate transport
APOCAHHA_02693 5.2e-215 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
APOCAHHA_02694 2.2e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
APOCAHHA_02695 6e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
APOCAHHA_02696 4.7e-311 araB 2.7.1.16 C Belongs to the ribulokinase family
APOCAHHA_02697 1.9e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
APOCAHHA_02698 1.9e-183 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
APOCAHHA_02699 8.4e-204 ysdC G COG1363 Cellulase M and related proteins
APOCAHHA_02700 9.2e-68 ysdB S Sigma-w pathway protein YsdB
APOCAHHA_02701 5.4e-43 ysdA S Membrane
APOCAHHA_02702 1.3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APOCAHHA_02703 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
APOCAHHA_02704 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APOCAHHA_02705 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
APOCAHHA_02706 9.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
APOCAHHA_02707 7.8e-129 lytT T COG3279 Response regulator of the LytR AlgR family
APOCAHHA_02708 0.0 lytS 2.7.13.3 T Histidine kinase
APOCAHHA_02709 1.8e-147 ysaA S HAD-hyrolase-like
APOCAHHA_02710 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APOCAHHA_02711 1.4e-150 ytxC S YtxC-like family
APOCAHHA_02712 6.9e-105 ytxB S SNARE associated Golgi protein
APOCAHHA_02713 6.6e-173 dnaI L Primosomal protein DnaI
APOCAHHA_02714 2.7e-263 dnaB L Membrane attachment protein
APOCAHHA_02715 3.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APOCAHHA_02716 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
APOCAHHA_02717 1.4e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APOCAHHA_02718 9.9e-67 ytcD K Transcriptional regulator
APOCAHHA_02719 5.6e-201 ytbD EGP Major facilitator Superfamily
APOCAHHA_02720 8.6e-156 ytbE S reductase
APOCAHHA_02721 2.1e-95 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APOCAHHA_02722 1.1e-107 ytaF P Probably functions as a manganese efflux pump
APOCAHHA_02723 2.3e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APOCAHHA_02724 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APOCAHHA_02725 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
APOCAHHA_02726 1.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_02727 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
APOCAHHA_02728 1.8e-242 icd 1.1.1.42 C isocitrate
APOCAHHA_02729 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
APOCAHHA_02730 4.7e-71 yeaL S membrane
APOCAHHA_02731 1.1e-190 ytvI S sporulation integral membrane protein YtvI
APOCAHHA_02732 6.2e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
APOCAHHA_02733 2e-308 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
APOCAHHA_02734 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APOCAHHA_02735 4.8e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
APOCAHHA_02736 1.9e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APOCAHHA_02737 9.8e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
APOCAHHA_02738 0.0 dnaE 2.7.7.7 L DNA polymerase
APOCAHHA_02739 3.2e-56 ytrH S Sporulation protein YtrH
APOCAHHA_02740 8.2e-69 ytrI
APOCAHHA_02741 9.2e-29
APOCAHHA_02742 5.1e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
APOCAHHA_02743 2.2e-45 ytpI S YtpI-like protein
APOCAHHA_02744 2.6e-239 ytoI K transcriptional regulator containing CBS domains
APOCAHHA_02745 4.2e-156 ytnM S membrane transporter protein
APOCAHHA_02746 1.3e-232 ytnL 3.5.1.47 E hydrolase activity
APOCAHHA_02747 3.8e-125 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
APOCAHHA_02748 5.9e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOCAHHA_02749 5.9e-42 ytnI O COG0695 Glutaredoxin and related proteins
APOCAHHA_02750 8.4e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOCAHHA_02751 2.5e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APOCAHHA_02752 2.3e-117 tcyM U Binding-protein-dependent transport system inner membrane component
APOCAHHA_02753 4.1e-122 tcyL P Binding-protein-dependent transport system inner membrane component
APOCAHHA_02754 4.6e-146 tcyK M Bacterial periplasmic substrate-binding proteins
APOCAHHA_02755 8.3e-148 tcyK ET Bacterial periplasmic substrate-binding proteins
APOCAHHA_02756 4.7e-99 ytmI K Acetyltransferase (GNAT) domain
APOCAHHA_02757 9.5e-172 ytlI K LysR substrate binding domain
APOCAHHA_02758 2.5e-129 ytkL S Belongs to the UPF0173 family
APOCAHHA_02759 9.3e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_02761 2.4e-264 argH 4.3.2.1 E argininosuccinate lyase
APOCAHHA_02762 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
APOCAHHA_02763 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
APOCAHHA_02764 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APOCAHHA_02765 1.6e-161 ytxK 2.1.1.72 L DNA methylase
APOCAHHA_02766 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APOCAHHA_02767 2.3e-70 ytfJ S Sporulation protein YtfJ
APOCAHHA_02768 3.1e-114 ytfI S Protein of unknown function (DUF2953)
APOCAHHA_02769 1.2e-85 yteJ S RDD family
APOCAHHA_02770 7.4e-178 sppA OU signal peptide peptidase SppA
APOCAHHA_02771 2.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APOCAHHA_02772 4.4e-302 ytcJ S amidohydrolase
APOCAHHA_02773 2.8e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APOCAHHA_02774 2e-29 sspB S spore protein
APOCAHHA_02775 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APOCAHHA_02776 6.8e-204 iscS2 2.8.1.7 E Cysteine desulfurase
APOCAHHA_02777 1e-174 braB E Component of the transport system for branched-chain amino acids
APOCAHHA_02778 2.7e-265 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APOCAHHA_02779 1.3e-111 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
APOCAHHA_02780 1.2e-106 yttP K Transcriptional regulator
APOCAHHA_02781 8.5e-87 ytsP 1.8.4.14 T GAF domain-containing protein
APOCAHHA_02782 1.9e-306 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
APOCAHHA_02783 1.6e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APOCAHHA_02785 5.7e-236 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APOCAHHA_02786 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APOCAHHA_02787 6.1e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
APOCAHHA_02788 1.6e-114 acuB S Domain in cystathionine beta-synthase and other proteins.
APOCAHHA_02789 3e-223 acuC BQ histone deacetylase
APOCAHHA_02790 4.1e-122 motS N Flagellar motor protein
APOCAHHA_02791 3e-145 motA N flagellar motor
APOCAHHA_02792 5.4e-181 ccpA K catabolite control protein A
APOCAHHA_02793 1.1e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
APOCAHHA_02794 1.1e-53 ytxJ O Protein of unknown function (DUF2847)
APOCAHHA_02795 6.5e-17 ytxH S COG4980 Gas vesicle protein
APOCAHHA_02796 4.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APOCAHHA_02797 4e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
APOCAHHA_02798 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
APOCAHHA_02799 7e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APOCAHHA_02800 8.3e-148 ytpQ S Belongs to the UPF0354 family
APOCAHHA_02801 2.3e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APOCAHHA_02802 1.3e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
APOCAHHA_02803 7e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
APOCAHHA_02804 2.2e-51 ytzB S small secreted protein
APOCAHHA_02805 4.3e-33 sfcA 1.1.1.38 C Malate dehydrogenase
APOCAHHA_02806 7.2e-275 sfcA 1.1.1.38 C Malate dehydrogenase
APOCAHHA_02807 7.9e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
APOCAHHA_02808 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APOCAHHA_02809 2e-45 ytzH S YtzH-like protein
APOCAHHA_02810 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
APOCAHHA_02811 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
APOCAHHA_02812 6.8e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
APOCAHHA_02813 3.3e-161 ytlQ
APOCAHHA_02814 1.1e-98 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
APOCAHHA_02815 1.2e-171 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APOCAHHA_02816 8.4e-265 pepV 3.5.1.18 E Dipeptidase
APOCAHHA_02817 2.7e-225 pbuO S permease
APOCAHHA_02818 3.3e-190 ythQ U Bacterial ABC transporter protein EcsB
APOCAHHA_02819 1.2e-42 ythP V ABC transporter
APOCAHHA_02820 3e-50 ythP V ABC transporter
APOCAHHA_02821 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
APOCAHHA_02822 2.6e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APOCAHHA_02823 1.1e-284 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOCAHHA_02824 2.3e-237 ytfP S HI0933-like protein
APOCAHHA_02825 6.2e-269 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
APOCAHHA_02826 3.1e-26 yteV S Sporulation protein Cse60
APOCAHHA_02827 4.2e-105 yteU S Integral membrane protein
APOCAHHA_02828 8.6e-248 yteT S Oxidoreductase family, C-terminal alpha/beta domain
APOCAHHA_02829 2.5e-81 yteS G transport
APOCAHHA_02830 2.7e-221 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APOCAHHA_02831 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
APOCAHHA_02832 0.0 ytdP K Transcriptional regulator
APOCAHHA_02833 1.7e-284 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
APOCAHHA_02834 8.4e-143 ytcP G COG0395 ABC-type sugar transport system, permease component
APOCAHHA_02835 2.9e-134 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
APOCAHHA_02836 3.1e-207 bioI 1.14.14.46 C Cytochrome P450
APOCAHHA_02837 7.8e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
APOCAHHA_02838 1.1e-121 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
APOCAHHA_02839 4.6e-216 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APOCAHHA_02840 1.2e-252 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
APOCAHHA_02841 3.2e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
APOCAHHA_02842 1.8e-57 S Psort location CytoplasmicMembrane, score
APOCAHHA_02843 4.6e-163 ytaP S Acetyl xylan esterase (AXE1)
APOCAHHA_02844 4.9e-185 msmR K Transcriptional regulator
APOCAHHA_02845 7e-242 msmE G Bacterial extracellular solute-binding protein
APOCAHHA_02846 2e-166 amyD P ABC transporter
APOCAHHA_02847 7e-142 amyC P ABC transporter (permease)
APOCAHHA_02848 1.4e-250 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
APOCAHHA_02849 4.8e-51 ytwF P Sulfurtransferase
APOCAHHA_02850 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
APOCAHHA_02851 4.5e-55 ytvB S Protein of unknown function (DUF4257)
APOCAHHA_02852 1.5e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
APOCAHHA_02853 9.5e-209 yttB EGP Major facilitator Superfamily
APOCAHHA_02854 2.9e-38 yttA 2.7.13.3 S Pfam Transposase IS66
APOCAHHA_02855 0.0 bceB V ABC transporter (permease)
APOCAHHA_02856 1.6e-137 bceA V ABC transporter, ATP-binding protein
APOCAHHA_02857 6.2e-177 T PhoQ Sensor
APOCAHHA_02858 3.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_02859 4e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
APOCAHHA_02860 1.2e-126 ytrE V ABC transporter, ATP-binding protein
APOCAHHA_02861 4.4e-151
APOCAHHA_02862 2.4e-133 P ABC-2 family transporter protein
APOCAHHA_02863 9.3e-161 ytrB P abc transporter atp-binding protein
APOCAHHA_02864 4e-63 ytrA K GntR family transcriptional regulator
APOCAHHA_02866 1.5e-40 ytzC S Protein of unknown function (DUF2524)
APOCAHHA_02867 6.8e-189 yhcC S Fe-S oxidoreductase
APOCAHHA_02868 1.5e-103 ytqB J Putative rRNA methylase
APOCAHHA_02869 1.4e-214 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
APOCAHHA_02870 2.8e-148 ytpA 3.1.1.5 I Alpha beta hydrolase
APOCAHHA_02871 1.9e-57 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
APOCAHHA_02872 1.9e-245 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
APOCAHHA_02873 0.0 asnB 6.3.5.4 E Asparagine synthase
APOCAHHA_02874 3.6e-224 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APOCAHHA_02875 5.9e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
APOCAHHA_02876 1.8e-37 ytmB S Protein of unknown function (DUF2584)
APOCAHHA_02877 6.7e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
APOCAHHA_02878 1.7e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
APOCAHHA_02879 2.7e-143 ytlC P ABC transporter
APOCAHHA_02880 4.4e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APOCAHHA_02881 3.1e-86 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
APOCAHHA_02882 1e-61 ytkC S Bacteriophage holin family
APOCAHHA_02883 2.1e-76 dps P Belongs to the Dps family
APOCAHHA_02885 3.5e-68 ytkA S YtkA-like
APOCAHHA_02886 1.3e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APOCAHHA_02887 9.4e-98 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
APOCAHHA_02888 6.1e-41 rpmE2 J Ribosomal protein L31
APOCAHHA_02889 2.6e-247 cydA 1.10.3.14 C oxidase, subunit
APOCAHHA_02890 2e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
APOCAHHA_02891 1.1e-24 S Domain of Unknown Function (DUF1540)
APOCAHHA_02892 3.8e-146 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
APOCAHHA_02893 9.4e-218 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APOCAHHA_02894 6.8e-136 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APOCAHHA_02895 7.2e-164 troA P Belongs to the bacterial solute-binding protein 9 family
APOCAHHA_02896 1.2e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
APOCAHHA_02897 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
APOCAHHA_02898 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APOCAHHA_02899 1.5e-149 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
APOCAHHA_02900 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
APOCAHHA_02901 6.1e-255 menF 5.4.4.2 HQ Isochorismate synthase
APOCAHHA_02902 3.5e-129 dksA T COG1734 DnaK suppressor protein
APOCAHHA_02903 1.5e-144 galU 2.7.7.9 M Nucleotidyl transferase
APOCAHHA_02904 2.9e-227 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APOCAHHA_02905 6.7e-173 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
APOCAHHA_02906 7.2e-228 ytcC M Glycosyltransferase Family 4
APOCAHHA_02908 6.3e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
APOCAHHA_02909 2.1e-213 cotSA M Glycosyl transferases group 1
APOCAHHA_02910 4.2e-200 cotI S Spore coat protein
APOCAHHA_02911 1.7e-73 tspO T membrane
APOCAHHA_02912 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
APOCAHHA_02913 1.2e-277 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
APOCAHHA_02914 1.1e-176 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
APOCAHHA_02915 1.1e-193 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APOCAHHA_02916 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
APOCAHHA_02925 7.8e-08
APOCAHHA_02926 1.3e-09
APOCAHHA_02933 2e-08
APOCAHHA_02938 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_02939 5.3e-88 thiT S Thiamine transporter protein (Thia_YuaJ)
APOCAHHA_02940 1.5e-89 M1-753 M FR47-like protein
APOCAHHA_02941 5.9e-187 yuaG 3.4.21.72 S protein conserved in bacteria
APOCAHHA_02942 7.4e-73 yuaF OU Membrane protein implicated in regulation of membrane protease activity
APOCAHHA_02943 5.7e-83 yuaE S DinB superfamily
APOCAHHA_02944 8.1e-105 yuaD
APOCAHHA_02945 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
APOCAHHA_02946 5.4e-278 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
APOCAHHA_02947 1.9e-92 yuaC K Belongs to the GbsR family
APOCAHHA_02948 1.4e-90 yuaB
APOCAHHA_02949 2.3e-119 ktrA P COG0569 K transport systems, NAD-binding component
APOCAHHA_02950 4.5e-231 ktrB P Potassium
APOCAHHA_02951 1e-38 yiaA S yiaA/B two helix domain
APOCAHHA_02952 4.6e-149 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APOCAHHA_02953 1.1e-260 yubD P Major Facilitator Superfamily
APOCAHHA_02954 1.6e-85 cdoA 1.13.11.20 S Cysteine dioxygenase type I
APOCAHHA_02955 1.4e-13
APOCAHHA_02956 8.2e-18
APOCAHHA_02959 3.2e-28 K Helix-turn-helix domain
APOCAHHA_02962 8.5e-40 S Bacterial toxin 44
APOCAHHA_02963 7.8e-25 S Family of unknown function (DUF5412)
APOCAHHA_02964 2e-101 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
APOCAHHA_02965 4.6e-31 xhlB S SPP1 phage holin
APOCAHHA_02966 8.6e-28 xhlA S Haemolysin XhlA
APOCAHHA_02971 9.6e-230 S peptidoglycan catabolic process
APOCAHHA_02972 2.6e-50
APOCAHHA_02973 2.3e-144
APOCAHHA_02974 8.4e-29 S Phage tail assembly chaperone protein, TAC
APOCAHHA_02975 6e-35 S Phage tail tube protein
APOCAHHA_02976 8.6e-29 S Protein of unknown function (DUF3168)
APOCAHHA_02977 1.2e-36 S Bacteriophage HK97-gp10, putative tail-component
APOCAHHA_02978 4.8e-28 S Phage head-tail joining protein
APOCAHHA_02979 1.9e-28 S Phage gp6-like head-tail connector protein
APOCAHHA_02982 3.7e-144 S Phage capsid family
APOCAHHA_02983 4.4e-58 S Domain of unknown function (DUF4355)
APOCAHHA_02985 1.3e-80 S Phage Mu protein F like protein
APOCAHHA_02986 1.6e-207 S Phage portal protein, SPP1 Gp6-like
APOCAHHA_02987 1e-216 S phage terminase, large subunit
APOCAHHA_02988 2.1e-86 yqaS L DNA packaging
APOCAHHA_02990 2.3e-78 L Transposase
APOCAHHA_03002 9.1e-126 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
APOCAHHA_03004 9e-26
APOCAHHA_03006 1.7e-25 yqaO S Phage-like element PBSX protein XtrA
APOCAHHA_03008 4e-54 S Protein of unknown function (DUF1064)
APOCAHHA_03009 1.4e-22 S YopX protein
APOCAHHA_03011 2e-80 xkdC L IstB-like ATP binding protein
APOCAHHA_03012 9.9e-25 L DnaD domain protein
APOCAHHA_03013 4.9e-135 recT L RecT family
APOCAHHA_03014 5.9e-153 yqaJ L YqaJ-like viral recombinase domain
APOCAHHA_03019 1.7e-86
APOCAHHA_03020 3.1e-67 S DNA binding
APOCAHHA_03021 5.8e-15 S Helix-turn-helix domain
APOCAHHA_03022 5.5e-17 K Helix-turn-helix domain
APOCAHHA_03023 3.3e-17 xre K Helix-turn-helix XRE-family like proteins
APOCAHHA_03024 1.5e-49
APOCAHHA_03025 2.4e-27 S Protein of unknown function (DUF4064)
APOCAHHA_03026 5.5e-49 xkdA E IrrE N-terminal-like domain
APOCAHHA_03027 7.1e-167 L Belongs to the 'phage' integrase family
APOCAHHA_03029 3.9e-132 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APOCAHHA_03030 7.4e-190 yubA S transporter activity
APOCAHHA_03031 5.5e-178 ygjR S Oxidoreductase
APOCAHHA_03032 3e-245 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
APOCAHHA_03033 1.8e-53 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
APOCAHHA_03034 2.2e-268 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
APOCAHHA_03035 2.3e-131 fucR K COG1349 Transcriptional regulators of sugar metabolism
APOCAHHA_03036 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
APOCAHHA_03037 4.7e-16 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
APOCAHHA_03039 6.6e-231 mcpA NT chemotaxis protein
APOCAHHA_03040 5.9e-288 mcpA NT chemotaxis protein
APOCAHHA_03041 3.7e-213 mcpA NT chemotaxis protein
APOCAHHA_03042 9.6e-222 mcpA NT chemotaxis protein
APOCAHHA_03043 4.6e-137 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
APOCAHHA_03044 3.5e-36
APOCAHHA_03045 3.1e-71 yugU S Uncharacterised protein family UPF0047
APOCAHHA_03046 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
APOCAHHA_03047 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
APOCAHHA_03048 3.2e-116 yugP S Zn-dependent protease
APOCAHHA_03049 8.7e-38
APOCAHHA_03050 3.2e-53 mstX S Membrane-integrating protein Mistic
APOCAHHA_03051 4.7e-177 yugO P COG1226 Kef-type K transport systems
APOCAHHA_03052 4.1e-71 yugN S YugN-like family
APOCAHHA_03054 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
APOCAHHA_03055 5.8e-227 yugK C Dehydrogenase
APOCAHHA_03056 8.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
APOCAHHA_03057 1.1e-34 yuzA S Domain of unknown function (DUF378)
APOCAHHA_03058 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
APOCAHHA_03059 3.1e-198 yugH 2.6.1.1 E Aminotransferase
APOCAHHA_03060 1.6e-85 alaR K Transcriptional regulator
APOCAHHA_03061 7.1e-155 yugF I Hydrolase
APOCAHHA_03062 3.7e-32 yugE S Domain of unknown function (DUF1871)
APOCAHHA_03063 4.8e-221 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
APOCAHHA_03064 1.4e-229 T PhoQ Sensor
APOCAHHA_03065 4.8e-69 kapB G Kinase associated protein B
APOCAHHA_03066 5.1e-113 kapD L the KinA pathway to sporulation
APOCAHHA_03068 2.3e-182 yuxJ EGP Major facilitator Superfamily
APOCAHHA_03069 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
APOCAHHA_03070 6.3e-75 yuxK S protein conserved in bacteria
APOCAHHA_03071 5.3e-77 yufK S Family of unknown function (DUF5366)
APOCAHHA_03072 4.9e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APOCAHHA_03073 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
APOCAHHA_03074 1.6e-188 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
APOCAHHA_03075 2.9e-266 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
APOCAHHA_03076 4.3e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
APOCAHHA_03077 3.3e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
APOCAHHA_03078 1.2e-231 maeN C COG3493 Na citrate symporter
APOCAHHA_03079 6.5e-15
APOCAHHA_03080 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APOCAHHA_03081 2e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOCAHHA_03082 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOCAHHA_03083 1.6e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOCAHHA_03084 1.2e-77 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOCAHHA_03085 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APOCAHHA_03086 7.5e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
APOCAHHA_03087 1.2e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
APOCAHHA_03088 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_03089 0.0 comP 2.7.13.3 T Histidine kinase
APOCAHHA_03091 5e-144 comQ H Belongs to the FPP GGPP synthase family
APOCAHHA_03093 3.8e-23 yuzC
APOCAHHA_03094 5e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
APOCAHHA_03095 3e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APOCAHHA_03096 4.7e-102 pncA Q COG1335 Amidases related to nicotinamidase
APOCAHHA_03097 9.7e-65 yueI S Protein of unknown function (DUF1694)
APOCAHHA_03098 4.1e-37 yueH S YueH-like protein
APOCAHHA_03099 7.3e-30 yueG S Spore germination protein gerPA/gerPF
APOCAHHA_03100 7.1e-190 yueF S transporter activity
APOCAHHA_03101 1.2e-62 S Protein of unknown function (DUF2283)
APOCAHHA_03102 2.9e-24 S Protein of unknown function (DUF2642)
APOCAHHA_03103 4.8e-96 yueE S phosphohydrolase
APOCAHHA_03104 3.9e-128 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_03105 1.8e-62 yueC S Family of unknown function (DUF5383)
APOCAHHA_03106 0.0 esaA S type VII secretion protein EsaA
APOCAHHA_03107 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
APOCAHHA_03108 1.6e-207 essB S WXG100 protein secretion system (Wss), protein YukC
APOCAHHA_03109 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
APOCAHHA_03110 2.8e-45 esxA S Belongs to the WXG100 family
APOCAHHA_03111 5e-221 yukF QT Transcriptional regulator
APOCAHHA_03112 2.3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
APOCAHHA_03113 6.6e-130 yukJ S Uncharacterized conserved protein (DUF2278)
APOCAHHA_03114 1.9e-35 mbtH S MbtH-like protein
APOCAHHA_03115 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_03116 6.6e-173 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
APOCAHHA_03117 1.5e-305 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
APOCAHHA_03118 3.5e-211 entC 5.4.4.2 HQ Isochorismate synthase
APOCAHHA_03119 4.2e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_03120 3.5e-160 besA S Putative esterase
APOCAHHA_03121 1.1e-117 yuiH S Oxidoreductase molybdopterin binding domain
APOCAHHA_03122 7.7e-90 bioY S Biotin biosynthesis protein
APOCAHHA_03123 4.8e-201 yuiF S antiporter
APOCAHHA_03124 6.5e-271 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
APOCAHHA_03125 1.5e-75 yuiD S protein conserved in bacteria
APOCAHHA_03126 6.8e-116 yuiC S protein conserved in bacteria
APOCAHHA_03127 1.2e-25 yuiB S Putative membrane protein
APOCAHHA_03128 5.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
APOCAHHA_03129 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
APOCAHHA_03131 4.3e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APOCAHHA_03132 1.8e-110 paiB K Putative FMN-binding domain
APOCAHHA_03133 1.4e-69 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOCAHHA_03134 4.1e-62 erpA S Belongs to the HesB IscA family
APOCAHHA_03135 2.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APOCAHHA_03136 1.6e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APOCAHHA_03137 3.2e-39 yuzB S Belongs to the UPF0349 family
APOCAHHA_03138 4.5e-199 yutJ 1.6.99.3 C NADH dehydrogenase
APOCAHHA_03139 1.3e-54 yuzD S protein conserved in bacteria
APOCAHHA_03140 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
APOCAHHA_03141 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
APOCAHHA_03142 1.4e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APOCAHHA_03143 3.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
APOCAHHA_03144 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
APOCAHHA_03145 9.1e-192 yutH S Spore coat protein
APOCAHHA_03146 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
APOCAHHA_03147 3.9e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APOCAHHA_03148 1.8e-72 yutE S Protein of unknown function DUF86
APOCAHHA_03149 9.7e-48 yutD S protein conserved in bacteria
APOCAHHA_03150 1e-108 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APOCAHHA_03151 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
APOCAHHA_03152 9.3e-194 lytH M Peptidase, M23
APOCAHHA_03153 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
APOCAHHA_03154 2e-46 yunC S Domain of unknown function (DUF1805)
APOCAHHA_03155 1.1e-261 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
APOCAHHA_03156 2.1e-138 yunE S membrane transporter protein
APOCAHHA_03157 5.6e-171 yunF S Protein of unknown function DUF72
APOCAHHA_03158 1.2e-55 yunG
APOCAHHA_03159 1.4e-248 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
APOCAHHA_03160 1e-298 pucR QT COG2508 Regulator of polyketide synthase expression
APOCAHHA_03161 1.5e-226 pbuX F Permease family
APOCAHHA_03162 6e-217 pbuX F xanthine
APOCAHHA_03163 1.9e-195 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
APOCAHHA_03164 2.1e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
APOCAHHA_03165 3.5e-81 K RNA polymerase
APOCAHHA_03168 3.5e-115 S Lantibiotic biosynthesis dehydratase C-term
APOCAHHA_03169 0.0
APOCAHHA_03170 3.9e-172 S Coenzyme PQQ synthesis protein D (PqqD)
APOCAHHA_03176 6.5e-99 C Nitroreductase family
APOCAHHA_03177 1.4e-272 C Nitroreductase family
APOCAHHA_03178 8.8e-103
APOCAHHA_03179 4.5e-236 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
APOCAHHA_03180 1e-157 V COG1131 ABC-type multidrug transport system, ATPase component
APOCAHHA_03181 8.3e-80 V ABC-2 type transporter
APOCAHHA_03182 2.4e-27 V ABC-2 type transporter
APOCAHHA_03184 3.8e-85 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
APOCAHHA_03185 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
APOCAHHA_03186 4.1e-134 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
APOCAHHA_03187 6.9e-102 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
APOCAHHA_03188 3.7e-174 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
APOCAHHA_03190 1.7e-232 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
APOCAHHA_03191 2.1e-227 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
APOCAHHA_03193 6.8e-164 bsn L Ribonuclease
APOCAHHA_03194 1.6e-197 msmX P Belongs to the ABC transporter superfamily
APOCAHHA_03195 3.1e-133 yurK K UTRA
APOCAHHA_03196 1.8e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
APOCAHHA_03197 2.3e-167 yurM P COG0395 ABC-type sugar transport system, permease component
APOCAHHA_03198 6.9e-156 yurN G Binding-protein-dependent transport system inner membrane component
APOCAHHA_03199 1.2e-233 yurO G COG1653 ABC-type sugar transport system, periplasmic component
APOCAHHA_03200 6.3e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
APOCAHHA_03201 1.5e-62 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
APOCAHHA_03202 6.9e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
APOCAHHA_03204 1.3e-39
APOCAHHA_03205 1.1e-62
APOCAHHA_03206 2.3e-236 L AAA ATPase domain
APOCAHHA_03207 9.9e-09 clpP 3.4.21.92 OU ATP-dependent Clp protease proteolytic subunit
APOCAHHA_03208 2.6e-16 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
APOCAHHA_03209 1e-101
APOCAHHA_03210 1.6e-40 L Phage integrase family
APOCAHHA_03211 6e-271 sufB O FeS cluster assembly
APOCAHHA_03212 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
APOCAHHA_03213 1.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APOCAHHA_03214 6.5e-243 sufD O assembly protein SufD
APOCAHHA_03215 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
APOCAHHA_03216 2.6e-61 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APOCAHHA_03217 3.2e-147 metQ P Belongs to the NlpA lipoprotein family
APOCAHHA_03218 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
APOCAHHA_03219 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APOCAHHA_03220 9.3e-56 yusD S SCP-2 sterol transfer family
APOCAHHA_03221 1.1e-53 traF CO Thioredoxin
APOCAHHA_03222 1.6e-58 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
APOCAHHA_03223 1.1e-39 yusG S Protein of unknown function (DUF2553)
APOCAHHA_03224 3.5e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
APOCAHHA_03225 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
APOCAHHA_03226 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
APOCAHHA_03227 1.8e-215 fadA 2.3.1.16 I Belongs to the thiolase family
APOCAHHA_03228 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
APOCAHHA_03229 8.1e-09 S YuzL-like protein
APOCAHHA_03230 3e-162 fadM E Proline dehydrogenase
APOCAHHA_03231 5.1e-40
APOCAHHA_03232 5.4e-53 yusN M Coat F domain
APOCAHHA_03233 1.5e-72 yusO K Iron dependent repressor, N-terminal DNA binding domain
APOCAHHA_03234 5.7e-289 yusP P Major facilitator superfamily
APOCAHHA_03235 1.6e-64 yusQ S Tautomerase enzyme
APOCAHHA_03236 8.5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_03237 5.5e-153 yusT K LysR substrate binding domain
APOCAHHA_03238 6.6e-47 yusU S Protein of unknown function (DUF2573)
APOCAHHA_03239 1.1e-152 yusV 3.6.3.34 HP ABC transporter
APOCAHHA_03240 1.1e-66 S YusW-like protein
APOCAHHA_03241 6.1e-300 pepF2 E COG1164 Oligoendopeptidase F
APOCAHHA_03242 1.7e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_03243 1e-78 dps P Ferritin-like domain
APOCAHHA_03244 1.1e-229 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APOCAHHA_03245 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_03246 3.7e-249 cssS 2.7.13.3 T PhoQ Sensor
APOCAHHA_03247 7.6e-155 yuxN K Transcriptional regulator
APOCAHHA_03248 9e-259 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APOCAHHA_03249 2.3e-24 S Protein of unknown function (DUF3970)
APOCAHHA_03250 7.7e-245 gerAA EG Spore germination protein
APOCAHHA_03251 2.8e-191 gerAB E Spore germination protein
APOCAHHA_03252 3e-180 gerAC S Spore germination B3/ GerAC like, C-terminal
APOCAHHA_03253 6.2e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_03254 7.4e-184 vraS 2.7.13.3 T Histidine kinase
APOCAHHA_03255 8.9e-125 yvqF S Cell wall-active antibiotics response 4TMS YvqF
APOCAHHA_03256 3e-111 liaG S Putative adhesin
APOCAHHA_03257 7.5e-102 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
APOCAHHA_03258 8.1e-61 liaI S membrane
APOCAHHA_03259 9.1e-226 yvqJ EGP Major facilitator Superfamily
APOCAHHA_03260 1.2e-98 yvqK 2.5.1.17 S Adenosyltransferase
APOCAHHA_03261 2.8e-225 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
APOCAHHA_03262 5e-177 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_03263 7.9e-166 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
APOCAHHA_03264 2.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_03265 7.6e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
APOCAHHA_03266 0.0 T PhoQ Sensor
APOCAHHA_03267 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_03268 1.9e-23
APOCAHHA_03269 1.9e-98 yvrI K RNA polymerase
APOCAHHA_03270 2.4e-19 S YvrJ protein family
APOCAHHA_03271 6.8e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
APOCAHHA_03272 2e-57 yvrL S Regulatory protein YrvL
APOCAHHA_03273 4.7e-195 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
APOCAHHA_03274 1.6e-123 macB V ABC transporter, ATP-binding protein
APOCAHHA_03275 1.8e-170 M Efflux transporter rnd family, mfp subunit
APOCAHHA_03276 5.4e-147 fhuC 3.6.3.34 HP ABC transporter
APOCAHHA_03277 1.5e-167 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_03278 7.4e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOCAHHA_03279 1.2e-174 fhuD P ABC transporter
APOCAHHA_03281 1e-230 yvsH E Arginine ornithine antiporter
APOCAHHA_03282 2.5e-15 S Small spore protein J (Spore_SspJ)
APOCAHHA_03283 3.9e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
APOCAHHA_03284 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APOCAHHA_03285 8.3e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
APOCAHHA_03286 9.5e-133 modA P COG0725 ABC-type molybdate transport system, periplasmic component
APOCAHHA_03287 3.2e-116 modB P COG4149 ABC-type molybdate transport system, permease component
APOCAHHA_03288 2.1e-154 yvgN S reductase
APOCAHHA_03289 8.7e-84 yvgO
APOCAHHA_03290 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
APOCAHHA_03291 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
APOCAHHA_03292 7.4e-208 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APOCAHHA_03293 1.9e-103 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APOCAHHA_03294 0.0 helD 3.6.4.12 L DNA helicase
APOCAHHA_03295 2.7e-106 yvgT S membrane
APOCAHHA_03296 1.1e-71 bdbC O Required for disulfide bond formation in some proteins
APOCAHHA_03297 1.4e-100 bdbD O Thioredoxin
APOCAHHA_03298 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
APOCAHHA_03299 0.0 copA 3.6.3.54 P P-type ATPase
APOCAHHA_03300 5.9e-29 copZ P Copper resistance protein CopZ
APOCAHHA_03301 2.2e-48 csoR S transcriptional
APOCAHHA_03302 6.5e-185 yvaA 1.1.1.371 S Oxidoreductase
APOCAHHA_03303 4.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APOCAHHA_03304 0.0 yvaC S Fusaric acid resistance protein-like
APOCAHHA_03305 9.1e-71 yvaD S Family of unknown function (DUF5360)
APOCAHHA_03306 7.7e-53 yvaE P Small Multidrug Resistance protein
APOCAHHA_03307 2.1e-97 K Bacterial regulatory proteins, tetR family
APOCAHHA_03308 3.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_03311 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
APOCAHHA_03312 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APOCAHHA_03313 5.6e-143 est 3.1.1.1 S Carboxylesterase
APOCAHHA_03314 2.4e-23 secG U Preprotein translocase subunit SecG
APOCAHHA_03315 1.6e-140 yvaM S Serine aminopeptidase, S33
APOCAHHA_03316 7.5e-36 yvzC K Transcriptional
APOCAHHA_03317 1.5e-68 K transcriptional
APOCAHHA_03318 3.7e-67 yvaO K Cro/C1-type HTH DNA-binding domain
APOCAHHA_03319 2.2e-54 yodB K transcriptional
APOCAHHA_03320 5.3e-205 NT chemotaxis protein
APOCAHHA_03321 2.4e-108 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
APOCAHHA_03322 4.1e-167 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APOCAHHA_03323 1.4e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
APOCAHHA_03324 5e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APOCAHHA_03325 6.6e-61 yvbF K Belongs to the GbsR family
APOCAHHA_03326 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
APOCAHHA_03327 2e-166 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APOCAHHA_03328 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
APOCAHHA_03329 7.5e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APOCAHHA_03330 3.9e-96 yvbF K Belongs to the GbsR family
APOCAHHA_03331 1.2e-101 yvbG U UPF0056 membrane protein
APOCAHHA_03332 1.4e-119 exoY M Membrane
APOCAHHA_03333 0.0 tcaA S response to antibiotic
APOCAHHA_03334 1.2e-77 yvbK 3.1.3.25 K acetyltransferase
APOCAHHA_03336 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APOCAHHA_03337 6.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
APOCAHHA_03338 1.3e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APOCAHHA_03339 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
APOCAHHA_03340 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APOCAHHA_03341 7.7e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APOCAHHA_03342 2.1e-252 araE EGP Major facilitator Superfamily
APOCAHHA_03343 3.9e-201 araR K transcriptional
APOCAHHA_03344 2.1e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOCAHHA_03345 1.5e-150 yvbU K Transcriptional regulator
APOCAHHA_03346 8.8e-154 yvbV EG EamA-like transporter family
APOCAHHA_03347 1.9e-234 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
APOCAHHA_03348 3.1e-187 yvbX S Glycosyl hydrolase
APOCAHHA_03349 4.8e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APOCAHHA_03350 2.3e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
APOCAHHA_03351 2.5e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APOCAHHA_03352 1.1e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_03353 6.6e-188 desK 2.7.13.3 T Histidine kinase
APOCAHHA_03354 2.7e-129 yvfS V COG0842 ABC-type multidrug transport system, permease component
APOCAHHA_03355 8.7e-146 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
APOCAHHA_03356 1.5e-152 rsbQ S Alpha/beta hydrolase family
APOCAHHA_03357 1.8e-191 rsbU 3.1.3.3 T response regulator
APOCAHHA_03358 2.7e-241 galA 3.2.1.89 G arabinogalactan
APOCAHHA_03359 0.0 lacA 3.2.1.23 G beta-galactosidase
APOCAHHA_03360 3.9e-148 ganQ P transport
APOCAHHA_03361 4.2e-231 malC P COG1175 ABC-type sugar transport systems, permease components
APOCAHHA_03362 1.2e-222 cycB G COG2182 Maltose-binding periplasmic proteins domains
APOCAHHA_03363 1.2e-180 lacR K Transcriptional regulator
APOCAHHA_03364 5.9e-113 yvfI K COG2186 Transcriptional regulators
APOCAHHA_03365 8.2e-307 yvfH C L-lactate permease
APOCAHHA_03366 1.9e-234 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
APOCAHHA_03367 1e-31 yvfG S YvfG protein
APOCAHHA_03368 1.4e-181 yvfF GM Exopolysaccharide biosynthesis protein
APOCAHHA_03369 1.3e-215 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
APOCAHHA_03370 4.3e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
APOCAHHA_03371 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APOCAHHA_03372 1.1e-249 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOCAHHA_03373 1.1e-187 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
APOCAHHA_03374 2.5e-200 epsI GM pyruvyl transferase
APOCAHHA_03375 1.3e-193 epsH GT2 S Glycosyltransferase like family 2
APOCAHHA_03376 1.7e-204 epsG S EpsG family
APOCAHHA_03377 1.2e-211 epsF GT4 M Glycosyl transferases group 1
APOCAHHA_03378 1.7e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APOCAHHA_03379 1.2e-208 epsD GT4 M Glycosyl transferase 4-like
APOCAHHA_03380 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
APOCAHHA_03381 8.7e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
APOCAHHA_03382 9.2e-119 ywqC M biosynthesis protein
APOCAHHA_03383 1.1e-75 slr K transcriptional
APOCAHHA_03384 3.5e-269 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
APOCAHHA_03386 1e-92 padC Q Phenolic acid decarboxylase
APOCAHHA_03387 8.4e-73 MA20_18690 S Protein of unknown function (DUF3237)
APOCAHHA_03388 7.9e-78 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
APOCAHHA_03389 1.9e-253 pbpE V Beta-lactamase
APOCAHHA_03390 5.7e-269 sacB 2.4.1.10 GH68 M levansucrase activity
APOCAHHA_03391 1.4e-308 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
APOCAHHA_03392 2.5e-294 yveA E amino acid
APOCAHHA_03393 7.4e-106 yvdT K Transcriptional regulator
APOCAHHA_03394 2.4e-48 ykkC P Small Multidrug Resistance protein
APOCAHHA_03395 9.2e-50 sugE P Small Multidrug Resistance protein
APOCAHHA_03396 4.5e-91 yvdQ S Protein of unknown function (DUF3231)
APOCAHHA_03398 3.5e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APOCAHHA_03399 4.1e-108 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
APOCAHHA_03400 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
APOCAHHA_03401 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
APOCAHHA_03402 1.2e-139 malA S Protein of unknown function (DUF1189)
APOCAHHA_03403 2.2e-143 malD P transport
APOCAHHA_03404 7.4e-239 malC P COG1175 ABC-type sugar transport systems, permease components
APOCAHHA_03405 1.5e-228 mdxE G COG2182 Maltose-binding periplasmic proteins domains
APOCAHHA_03406 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
APOCAHHA_03407 4.1e-170 yvdE K Transcriptional regulator
APOCAHHA_03408 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
APOCAHHA_03409 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
APOCAHHA_03410 3.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
APOCAHHA_03411 1.2e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
APOCAHHA_03412 2.5e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOCAHHA_03413 0.0 yxdM V ABC transporter (permease)
APOCAHHA_03414 5.8e-138 yvcR V ABC transporter, ATP-binding protein
APOCAHHA_03415 2.5e-192 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
APOCAHHA_03416 3.7e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_03417 3.9e-33
APOCAHHA_03418 1.4e-136 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
APOCAHHA_03419 1.6e-36 crh G Phosphocarrier protein Chr
APOCAHHA_03420 1.4e-170 whiA K May be required for sporulation
APOCAHHA_03421 8.9e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
APOCAHHA_03422 3.7e-165 rapZ S Displays ATPase and GTPase activities
APOCAHHA_03423 1.5e-88 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
APOCAHHA_03424 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APOCAHHA_03425 2.8e-98 usp CBM50 M protein conserved in bacteria
APOCAHHA_03426 4.6e-274 S COG0457 FOG TPR repeat
APOCAHHA_03427 0.0 msbA2 3.6.3.44 V ABC transporter
APOCAHHA_03429 7.2e-251
APOCAHHA_03430 1.2e-67
APOCAHHA_03431 1.9e-60
APOCAHHA_03432 2.2e-107
APOCAHHA_03434 1.6e-68
APOCAHHA_03435 4e-96 Otg1 S Predicted membrane protein (DUF2339)
APOCAHHA_03436 2.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
APOCAHHA_03437 9.9e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APOCAHHA_03438 6.3e-91 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APOCAHHA_03439 5e-19 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APOCAHHA_03440 8.4e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APOCAHHA_03441 1.3e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
APOCAHHA_03442 2e-184 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APOCAHHA_03443 4.9e-24 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APOCAHHA_03444 2e-74 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APOCAHHA_03445 4.7e-216 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APOCAHHA_03446 2e-135 yvpB NU protein conserved in bacteria
APOCAHHA_03447 7.4e-118 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
APOCAHHA_03448 3.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
APOCAHHA_03449 2.7e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
APOCAHHA_03450 5.8e-161 yvoD P COG0370 Fe2 transport system protein B
APOCAHHA_03451 4.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APOCAHHA_03452 1.1e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APOCAHHA_03453 5e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
APOCAHHA_03454 5.2e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APOCAHHA_03455 1.5e-127 yvoA K transcriptional
APOCAHHA_03456 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
APOCAHHA_03457 1.2e-50 yvlD S Membrane
APOCAHHA_03458 4.4e-26 pspB KT PspC domain
APOCAHHA_03459 3.5e-165 yvlB S Putative adhesin
APOCAHHA_03460 1e-48 yvlA
APOCAHHA_03461 6.2e-32 yvkN
APOCAHHA_03462 2.7e-112 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APOCAHHA_03463 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APOCAHHA_03464 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APOCAHHA_03465 1.2e-30 csbA S protein conserved in bacteria
APOCAHHA_03466 0.0 yvkC 2.7.9.2 GT Phosphotransferase
APOCAHHA_03467 1.1e-98 yvkB K Transcriptional regulator
APOCAHHA_03468 2e-223 yvkA EGP Major facilitator Superfamily
APOCAHHA_03469 3.9e-218 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APOCAHHA_03470 5.3e-56 swrA S Swarming motility protein
APOCAHHA_03471 2.2e-268 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
APOCAHHA_03472 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
APOCAHHA_03473 3.9e-122 ftsE D cell division ATP-binding protein FtsE
APOCAHHA_03474 5.9e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
APOCAHHA_03475 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
APOCAHHA_03476 2.3e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APOCAHHA_03477 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APOCAHHA_03478 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APOCAHHA_03479 1e-50
APOCAHHA_03480 1.9e-08 fliT S bacterial-type flagellum organization
APOCAHHA_03481 4.2e-68 fliS N flagellar protein FliS
APOCAHHA_03482 1.9e-251 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
APOCAHHA_03483 3.7e-54 flaG N flagellar protein FlaG
APOCAHHA_03484 2.1e-123 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APOCAHHA_03485 8.2e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
APOCAHHA_03486 2.4e-69 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
APOCAHHA_03487 5.3e-48 yviE
APOCAHHA_03488 3e-154 flgL N Belongs to the bacterial flagellin family
APOCAHHA_03489 9.5e-262 flgK N flagellar hook-associated protein
APOCAHHA_03490 2.3e-76 flgN NOU FlgN protein
APOCAHHA_03491 2.6e-37 flgM KNU Negative regulator of flagellin synthesis
APOCAHHA_03492 3e-72 yvyF S flagellar protein
APOCAHHA_03493 2.4e-78 comFC S Phosphoribosyl transferase domain
APOCAHHA_03494 4.1e-44 comFB S Late competence development protein ComFB
APOCAHHA_03495 7.8e-247 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
APOCAHHA_03496 1.8e-153 degV S protein conserved in bacteria
APOCAHHA_03497 8.4e-63 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_03498 2.5e-31 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APOCAHHA_03499 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
APOCAHHA_03500 1.7e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
APOCAHHA_03501 1.2e-160 yvhJ K Transcriptional regulator
APOCAHHA_03502 1.3e-180 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
APOCAHHA_03503 8.1e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
APOCAHHA_03504 2.6e-143 tuaG GT2 M Glycosyltransferase like family 2
APOCAHHA_03505 1.9e-113 tuaF M protein involved in exopolysaccharide biosynthesis
APOCAHHA_03506 4.9e-255 tuaE M Teichuronic acid biosynthesis protein
APOCAHHA_03507 1.2e-255 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APOCAHHA_03508 1.1e-212 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
APOCAHHA_03509 3.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOCAHHA_03510 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APOCAHHA_03511 4.5e-264 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APOCAHHA_03512 0.0 lytB 3.5.1.28 D Stage II sporulation protein
APOCAHHA_03513 5.1e-37
APOCAHHA_03514 7.5e-161 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
APOCAHHA_03515 4.8e-210 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APOCAHHA_03516 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APOCAHHA_03517 6e-15 tagG GM Transport permease protein
APOCAHHA_03518 1.6e-202 M Glycosyl transferase, family 2
APOCAHHA_03519 6.1e-128 vioA 2.6.1.33 E DegT/DnrJ/EryC1/StrS aminotransferase family
APOCAHHA_03520 4.4e-167 6.3.5.5 S ATP-grasp domain
APOCAHHA_03521 3.3e-184 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APOCAHHA_03522 3e-13 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APOCAHHA_03523 7.1e-144 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APOCAHHA_03524 3.3e-134 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APOCAHHA_03525 2e-09 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APOCAHHA_03526 2.3e-24 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
APOCAHHA_03527 1.3e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APOCAHHA_03528 1.7e-261 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
APOCAHHA_03529 1.7e-148 tagG GM Transport permease protein
APOCAHHA_03530 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APOCAHHA_03531 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
APOCAHHA_03532 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
APOCAHHA_03533 1.9e-141 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
APOCAHHA_03534 8.9e-196 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APOCAHHA_03535 3.8e-259
APOCAHHA_03536 4.3e-209 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APOCAHHA_03537 1.7e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
APOCAHHA_03538 2.3e-257 gerBA EG Spore germination protein
APOCAHHA_03539 4.7e-194 gerBB E Spore germination protein
APOCAHHA_03540 3.1e-201 gerAC S Spore germination protein
APOCAHHA_03541 1.2e-244 ywtG EGP Major facilitator Superfamily
APOCAHHA_03542 2.7e-169 ywtF K Transcriptional regulator
APOCAHHA_03543 5e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
APOCAHHA_03544 3.7e-233 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APOCAHHA_03545 1.3e-18 ywtC
APOCAHHA_03546 9.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
APOCAHHA_03547 8.6e-70 pgsC S biosynthesis protein
APOCAHHA_03548 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
APOCAHHA_03549 3.8e-171 rbsR K transcriptional
APOCAHHA_03550 1.3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APOCAHHA_03551 1.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APOCAHHA_03552 1.5e-272 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
APOCAHHA_03553 2.3e-152 rbsC G Belongs to the binding-protein-dependent transport system permease family
APOCAHHA_03554 3.8e-157 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
APOCAHHA_03555 2.6e-89 batE T Sh3 type 3 domain protein
APOCAHHA_03556 3e-47 ywsA S Protein of unknown function (DUF3892)
APOCAHHA_03557 3.1e-95 ywrO S NADPH-quinone reductase (modulator of drug activity B)
APOCAHHA_03558 3.4e-143 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
APOCAHHA_03559 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
APOCAHHA_03560 4.5e-166 alsR K LysR substrate binding domain
APOCAHHA_03561 5.6e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APOCAHHA_03562 1.7e-117 ywrJ
APOCAHHA_03563 4.5e-123 cotB
APOCAHHA_03564 1.5e-205 cotH M Spore Coat
APOCAHHA_03566 6e-106 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APOCAHHA_03567 2.9e-25 S Domain of unknown function (DUF4181)
APOCAHHA_03568 1.9e-292 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
APOCAHHA_03569 8e-82 ywrC K Transcriptional regulator
APOCAHHA_03570 2.7e-100 ywrB P Chromate transporter
APOCAHHA_03571 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
APOCAHHA_03573 7.2e-95 ywqN S NAD(P)H-dependent
APOCAHHA_03574 1.6e-160 K Transcriptional regulator
APOCAHHA_03575 6.9e-122 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
APOCAHHA_03576 4.1e-97
APOCAHHA_03577 7.9e-61
APOCAHHA_03578 3.7e-82 ywqJ S Pre-toxin TG
APOCAHHA_03579 5.2e-17
APOCAHHA_03580 7.9e-43
APOCAHHA_03581 5.1e-214 ywqJ L nucleic acid phosphodiester bond hydrolysis
APOCAHHA_03582 3.9e-38 ywqI S Family of unknown function (DUF5344)
APOCAHHA_03583 3.7e-22 S Domain of unknown function (DUF5082)
APOCAHHA_03584 1.3e-150 ywqG S Domain of unknown function (DUF1963)
APOCAHHA_03585 1.1e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APOCAHHA_03586 3.4e-135 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
APOCAHHA_03587 1.9e-113 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
APOCAHHA_03588 1.1e-114 ywqC M biosynthesis protein
APOCAHHA_03589 1.2e-17
APOCAHHA_03590 1.5e-302 ywqB S SWIM zinc finger
APOCAHHA_03591 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
APOCAHHA_03592 2.2e-151 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
APOCAHHA_03593 3.5e-135 glcR K COG1349 Transcriptional regulators of sugar metabolism
APOCAHHA_03594 1.4e-56 ssbB L Single-stranded DNA-binding protein
APOCAHHA_03595 8.4e-66 ywpG
APOCAHHA_03596 1.8e-66 ywpF S YwpF-like protein
APOCAHHA_03597 5.1e-84 srtA 3.4.22.70 M Sortase family
APOCAHHA_03598 0.0 M1-568 M cell wall anchor domain
APOCAHHA_03599 3.9e-169 M1-574 T Transcriptional regulatory protein, C terminal
APOCAHHA_03600 0.0 ywpD T PhoQ Sensor
APOCAHHA_03601 6.3e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APOCAHHA_03602 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APOCAHHA_03603 3.5e-194 S aspartate phosphatase
APOCAHHA_03604 4.1e-139 flhP N flagellar basal body
APOCAHHA_03605 3.9e-121 flhO N flagellar basal body
APOCAHHA_03606 6e-180 mbl D Rod shape-determining protein
APOCAHHA_03607 3e-44 spoIIID K Stage III sporulation protein D
APOCAHHA_03608 4.7e-70 ywoH K COG1846 Transcriptional regulators
APOCAHHA_03609 3.5e-211 ywoG EGP Major facilitator Superfamily
APOCAHHA_03610 6.3e-215 ywoF P Right handed beta helix region
APOCAHHA_03611 1.3e-276 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
APOCAHHA_03612 1.1e-237 ywoD EGP Major facilitator superfamily
APOCAHHA_03613 1.8e-101 phzA Q Isochorismatase family
APOCAHHA_03614 5.3e-75
APOCAHHA_03615 1.1e-223 amt P Ammonium transporter
APOCAHHA_03616 7.7e-58 nrgB K Belongs to the P(II) protein family
APOCAHHA_03617 1.9e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
APOCAHHA_03618 5.1e-72 ywnJ S VanZ like family
APOCAHHA_03619 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
APOCAHHA_03620 5e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
APOCAHHA_03621 6.1e-11 ywnC S Family of unknown function (DUF5362)
APOCAHHA_03622 4.6e-68 ywnF S Family of unknown function (DUF5392)
APOCAHHA_03623 2.7e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APOCAHHA_03624 1.3e-137 mta K transcriptional
APOCAHHA_03625 1.7e-58 ywnC S Family of unknown function (DUF5362)
APOCAHHA_03626 2e-112 ywnB S NAD(P)H-binding
APOCAHHA_03627 2.8e-64 ywnA K Transcriptional regulator
APOCAHHA_03628 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
APOCAHHA_03629 9.6e-29 ureB 3.5.1.5 E Belongs to the urease beta subunit family
APOCAHHA_03630 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
APOCAHHA_03631 1.3e-112 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
APOCAHHA_03632 8e-121 urtD S ATPases associated with a variety of cellular activities
APOCAHHA_03633 4.3e-184 urtC E Belongs to the binding-protein-dependent transport system permease family
APOCAHHA_03634 1e-146 urtB E Belongs to the binding-protein-dependent transport system permease family
APOCAHHA_03635 1.1e-218 urtA E Receptor family ligand binding region
APOCAHHA_03636 3.6e-09 csbD K CsbD-like
APOCAHHA_03637 1.1e-83 ywmF S Peptidase M50
APOCAHHA_03638 3e-103 S response regulator aspartate phosphatase
APOCAHHA_03639 2.9e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APOCAHHA_03640 1.3e-140 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
APOCAHHA_03642 4.9e-117 ywmD S protein containing a von Willebrand factor type A (vWA) domain
APOCAHHA_03643 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
APOCAHHA_03644 4.1e-176 spoIID D Stage II sporulation protein D
APOCAHHA_03645 7.9e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APOCAHHA_03646 2.5e-130 ywmB S TATA-box binding
APOCAHHA_03647 1.3e-32 ywzB S membrane
APOCAHHA_03648 1.7e-84 ywmA
APOCAHHA_03649 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
APOCAHHA_03650 5.5e-264 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APOCAHHA_03651 1e-148 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APOCAHHA_03652 2.2e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APOCAHHA_03653 3.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APOCAHHA_03654 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APOCAHHA_03655 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APOCAHHA_03656 7.9e-129 atpB C it plays a direct role in the translocation of protons across the membrane
APOCAHHA_03657 2.5e-62 atpI S ATP synthase
APOCAHHA_03658 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APOCAHHA_03659 7.8e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APOCAHHA_03660 2.2e-91 ywlG S Belongs to the UPF0340 family
APOCAHHA_03661 4.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
APOCAHHA_03662 2e-74 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APOCAHHA_03663 4.2e-90 mntP P Probably functions as a manganese efflux pump
APOCAHHA_03664 4.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APOCAHHA_03665 2.2e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
APOCAHHA_03666 9.8e-110 spoIIR S stage II sporulation protein R
APOCAHHA_03667 4.8e-55 ywlA S Uncharacterised protein family (UPF0715)
APOCAHHA_03669 1.3e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APOCAHHA_03670 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APOCAHHA_03671 2.7e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOCAHHA_03672 1.7e-88 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
APOCAHHA_03673 4.7e-158 ywkB S Membrane transport protein
APOCAHHA_03674 0.0 sfcA 1.1.1.38 C malic enzyme
APOCAHHA_03675 7e-104 tdk 2.7.1.21 F thymidine kinase
APOCAHHA_03676 1.1e-32 rpmE J Binds the 23S rRNA
APOCAHHA_03677 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
APOCAHHA_03678 1.6e-174 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
APOCAHHA_03679 2.5e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APOCAHHA_03680 3.4e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
APOCAHHA_03681 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
APOCAHHA_03682 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
APOCAHHA_03683 3e-90 ywjG S Domain of unknown function (DUF2529)
APOCAHHA_03684 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APOCAHHA_03685 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APOCAHHA_03686 3.5e-208 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
APOCAHHA_03687 0.0 fadF C COG0247 Fe-S oxidoreductase
APOCAHHA_03688 4.3e-217 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
APOCAHHA_03689 3.4e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
APOCAHHA_03690 7.9e-42 ywjC
APOCAHHA_03691 2.6e-86 ywjB H RibD C-terminal domain
APOCAHHA_03692 0.0 ywjA V ABC transporter
APOCAHHA_03693 1.9e-283 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APOCAHHA_03694 1.3e-87 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APOCAHHA_03695 6.5e-122 narI 1.7.5.1 C nitrate reductase, gamma
APOCAHHA_03696 6.6e-96 narJ 1.7.5.1 C nitrate reductase
APOCAHHA_03697 1.9e-208 narH 1.7.5.1 C Nitrate reductase, beta
APOCAHHA_03698 3.5e-79 narH 1.7.5.1 C Nitrate reductase, beta
APOCAHHA_03699 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOCAHHA_03700 2.6e-55 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOCAHHA_03701 1.5e-83 arfM T cyclic nucleotide binding
APOCAHHA_03702 9.4e-135 ywiC S YwiC-like protein
APOCAHHA_03703 3.8e-128 fnr K helix_turn_helix, cAMP Regulatory protein
APOCAHHA_03704 1.1e-210 narK P COG2223 Nitrate nitrite transporter
APOCAHHA_03705 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
APOCAHHA_03706 8.8e-72 ywiB S protein conserved in bacteria
APOCAHHA_03707 1e-07 S Bacteriocin subtilosin A
APOCAHHA_03708 2.1e-268 C Fe-S oxidoreductases
APOCAHHA_03710 9.1e-130 cbiO V ABC transporter
APOCAHHA_03711 9.4e-226 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
APOCAHHA_03712 1.1e-212 2.7.1.26, 2.7.7.2 L Peptidase, M16
APOCAHHA_03713 1.3e-232 L Peptidase, M16
APOCAHHA_03715 7.6e-234 ywhL CO amine dehydrogenase activity
APOCAHHA_03716 4.9e-201 ywhK CO amine dehydrogenase activity
APOCAHHA_03717 9.5e-73 S aspartate phosphatase
APOCAHHA_03719 1e-07
APOCAHHA_03720 1.9e-16
APOCAHHA_03724 1.5e-28 V ABC transporter, ATP-binding protein
APOCAHHA_03725 2e-08 V ATPases associated with a variety of cellular activities
APOCAHHA_03727 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
APOCAHHA_03728 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
APOCAHHA_03729 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APOCAHHA_03730 0.0 V Beta-lactamase
APOCAHHA_03731 0.0 yvfT T helix_turn_helix, Lux Regulon
APOCAHHA_03732 1.2e-82 S Putative sensor
APOCAHHA_03733 1.1e-144 bla 3.5.2.6 V beta-lactamase
APOCAHHA_03734 5.8e-94 ywhD S YwhD family
APOCAHHA_03735 2.5e-118 ywhC S Peptidase family M50
APOCAHHA_03736 7.9e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
APOCAHHA_03737 3.3e-71 ywhA K Transcriptional regulator
APOCAHHA_03738 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APOCAHHA_03740 2.6e-234 mmr U Major Facilitator Superfamily
APOCAHHA_03741 1.3e-73 yffB K Transcriptional regulator
APOCAHHA_03742 2.1e-88 ywgA 2.1.1.72, 3.1.21.3
APOCAHHA_03743 4.3e-255 ywfO S COG1078 HD superfamily phosphohydrolases
APOCAHHA_03744 3.1e-36 ywzC S Belongs to the UPF0741 family
APOCAHHA_03745 6.2e-108 rsfA_1
APOCAHHA_03746 1.7e-154 ywfM EG EamA-like transporter family
APOCAHHA_03747 6.9e-153 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
APOCAHHA_03748 1.2e-150 cysL K Transcriptional regulator
APOCAHHA_03749 1.3e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
APOCAHHA_03750 7.4e-146 ywfI C May function as heme-dependent peroxidase
APOCAHHA_03751 1.9e-136 IQ Enoyl-(Acyl carrier protein) reductase
APOCAHHA_03752 5.2e-231 ywfG 2.6.1.83 E Aminotransferase class I and II
APOCAHHA_03753 6.8e-207 bacE EGP Major facilitator Superfamily
APOCAHHA_03754 6.3e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
APOCAHHA_03755 1.1e-136 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_03756 4.9e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
APOCAHHA_03757 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
APOCAHHA_03758 4.5e-201 ywfA EGP Major facilitator Superfamily
APOCAHHA_03759 1.2e-258 lysP E amino acid
APOCAHHA_03760 0.0 rocB E arginine degradation protein
APOCAHHA_03761 1.5e-294 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
APOCAHHA_03762 8.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
APOCAHHA_03763 6.4e-76
APOCAHHA_03764 2.3e-86 spsL 5.1.3.13 M Spore Coat
APOCAHHA_03765 2.9e-151 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APOCAHHA_03766 2.4e-178 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APOCAHHA_03767 2.2e-134 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APOCAHHA_03768 3.7e-177 spsG M Spore Coat
APOCAHHA_03769 4.1e-122 spsF M Spore Coat
APOCAHHA_03770 5.8e-208 spsE 2.5.1.56 M acid synthase
APOCAHHA_03771 4.6e-160 spsD 2.3.1.210 K Spore Coat
APOCAHHA_03772 3.7e-221 spsC E Belongs to the DegT DnrJ EryC1 family
APOCAHHA_03773 6.6e-273 spsB M Capsule polysaccharide biosynthesis protein
APOCAHHA_03774 1e-142 spsA M Spore Coat
APOCAHHA_03775 3.8e-72 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
APOCAHHA_03776 7.4e-59 ywdK S small membrane protein
APOCAHHA_03777 5e-235 ywdJ F Xanthine uracil
APOCAHHA_03778 2.4e-42 ywdI S Family of unknown function (DUF5327)
APOCAHHA_03779 1e-254 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
APOCAHHA_03780 2.1e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APOCAHHA_03781 4.7e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
APOCAHHA_03783 1.2e-77 ywdD
APOCAHHA_03784 6.8e-13 ywdD
APOCAHHA_03785 1.6e-55 pex K Transcriptional regulator PadR-like family
APOCAHHA_03786 1e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APOCAHHA_03787 5.3e-29 ywdA
APOCAHHA_03788 1.2e-279 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
APOCAHHA_03789 1.7e-249 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOCAHHA_03790 8.5e-134 focA P Formate/nitrite transporter
APOCAHHA_03791 3.8e-148 sacT K transcriptional antiterminator
APOCAHHA_03794 0.0 vpr O Belongs to the peptidase S8 family
APOCAHHA_03795 8.3e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOCAHHA_03796 1.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
APOCAHHA_03797 1.1e-188 rodA D Belongs to the SEDS family
APOCAHHA_03798 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
APOCAHHA_03799 2.2e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
APOCAHHA_03800 6.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
APOCAHHA_03801 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APOCAHHA_03802 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
APOCAHHA_03803 1e-35 ywzA S membrane
APOCAHHA_03804 2.3e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
APOCAHHA_03805 4.3e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APOCAHHA_03806 6.2e-59 gtcA S GtrA-like protein
APOCAHHA_03807 1.1e-118 ywcC K transcriptional regulator
APOCAHHA_03809 1.7e-48 ywcB S Protein of unknown function, DUF485
APOCAHHA_03810 5.3e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APOCAHHA_03811 5.7e-109 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
APOCAHHA_03812 3.5e-222 ywbN P Dyp-type peroxidase family protein
APOCAHHA_03813 7.9e-184 ycdO P periplasmic lipoprotein involved in iron transport
APOCAHHA_03814 6.7e-249 P COG0672 High-affinity Fe2 Pb2 permease
APOCAHHA_03815 7.9e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APOCAHHA_03816 1.6e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APOCAHHA_03817 2.8e-152 ywbI K Transcriptional regulator
APOCAHHA_03818 1.7e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
APOCAHHA_03819 1.3e-109 ywbG M effector of murein hydrolase
APOCAHHA_03820 1.3e-208 ywbF EGP Major facilitator Superfamily
APOCAHHA_03821 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
APOCAHHA_03822 1.4e-81 ywbD 2.1.1.191 J Methyltransferase
APOCAHHA_03823 4.2e-121 ywbD 2.1.1.191 J Methyltransferase
APOCAHHA_03824 4.9e-66 ywbC 4.4.1.5 E glyoxalase
APOCAHHA_03825 5.3e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
APOCAHHA_03826 4e-111 ywbB S Protein of unknown function (DUF2711)
APOCAHHA_03827 1.1e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APOCAHHA_03828 2.5e-267 epr 3.4.21.62 O Belongs to the peptidase S8 family
APOCAHHA_03829 1.7e-238 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOCAHHA_03830 4.9e-151 sacY K transcriptional antiterminator
APOCAHHA_03831 1.9e-166 gspA M General stress
APOCAHHA_03832 5.9e-121 ywaF S Integral membrane protein
APOCAHHA_03833 2.9e-85 ywaE K Transcriptional regulator
APOCAHHA_03834 3.5e-230 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APOCAHHA_03835 1.9e-245 ywaD 3.4.11.10, 3.4.11.6 S PA domain
APOCAHHA_03836 4e-92 K Helix-turn-helix XRE-family like proteins
APOCAHHA_03837 5.5e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
APOCAHHA_03838 8e-131 ynfM EGP Major facilitator Superfamily
APOCAHHA_03839 1.1e-115 ywaC 2.7.6.5 S protein conserved in bacteria
APOCAHHA_03840 3.5e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
APOCAHHA_03842 5e-14 S D-Ala-teichoic acid biosynthesis protein
APOCAHHA_03843 3.6e-285 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_03844 2.6e-230 dltB M membrane protein involved in D-alanine export
APOCAHHA_03845 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOCAHHA_03846 5.9e-227 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APOCAHHA_03847 2.7e-132 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_03848 1.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
APOCAHHA_03849 3.2e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APOCAHHA_03850 1.1e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
APOCAHHA_03851 1.6e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APOCAHHA_03852 1.5e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
APOCAHHA_03853 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
APOCAHHA_03854 6.8e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
APOCAHHA_03855 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
APOCAHHA_03856 8.4e-205 yxlH EGP Major facilitator Superfamily
APOCAHHA_03857 1.7e-134 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APOCAHHA_03858 9.4e-161 yxlF V ABC transporter, ATP-binding protein
APOCAHHA_03859 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
APOCAHHA_03860 1.3e-28
APOCAHHA_03861 2.1e-38 yxlC S Family of unknown function (DUF5345)
APOCAHHA_03862 7.1e-87 sigY K Belongs to the sigma-70 factor family. ECF subfamily
APOCAHHA_03863 1.4e-251 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
APOCAHHA_03864 3.7e-151 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APOCAHHA_03865 9.6e-303 cydD V ATP-binding protein
APOCAHHA_03866 7.5e-308 cydD V ATP-binding
APOCAHHA_03867 1.8e-187 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
APOCAHHA_03868 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
APOCAHHA_03869 1.6e-228 cimH C COG3493 Na citrate symporter
APOCAHHA_03870 1.4e-301 3.4.24.84 O Peptidase family M48
APOCAHHA_03872 3.9e-148 yxkH G Polysaccharide deacetylase
APOCAHHA_03873 5.9e-205 msmK P Belongs to the ABC transporter superfamily
APOCAHHA_03874 3e-159 lrp QT PucR C-terminal helix-turn-helix domain
APOCAHHA_03875 1e-268 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APOCAHHA_03876 4.3e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APOCAHHA_03877 3.1e-138
APOCAHHA_03878 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
APOCAHHA_03879 5.9e-77 S Protein of unknown function (DUF1453)
APOCAHHA_03880 1.2e-166 yxjM T Signal transduction histidine kinase
APOCAHHA_03881 8.3e-114 K helix_turn_helix, Lux Regulon
APOCAHHA_03882 9.2e-231 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
APOCAHHA_03884 1.6e-85 yxjI S LURP-one-related
APOCAHHA_03885 2.5e-214 yxjG 2.1.1.14 E Methionine synthase
APOCAHHA_03886 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
APOCAHHA_03887 2.6e-130 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
APOCAHHA_03888 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APOCAHHA_03889 8.5e-128 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APOCAHHA_03890 1.8e-246 yxjC EG COG2610 H gluconate symporter and related permeases
APOCAHHA_03891 4.2e-150 rlmA 2.1.1.187 Q Methyltransferase domain
APOCAHHA_03892 5.1e-75 IQ Enoyl-(Acyl carrier protein) reductase
APOCAHHA_03893 7.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APOCAHHA_03894 2.5e-105 T Domain of unknown function (DUF4163)
APOCAHHA_03895 1.2e-45 yxiS
APOCAHHA_03896 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
APOCAHHA_03897 1.6e-222 citH C Citrate transporter
APOCAHHA_03898 7.3e-143 exoK GH16 M licheninase activity
APOCAHHA_03899 4.5e-149 licT K transcriptional antiterminator
APOCAHHA_03900 4.2e-100
APOCAHHA_03901 1.4e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
APOCAHHA_03902 1.1e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
APOCAHHA_03903 1e-207 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
APOCAHHA_03909 8.9e-35
APOCAHHA_03910 1.5e-88 yxiI S Protein of unknown function (DUF2716)
APOCAHHA_03911 1.5e-136
APOCAHHA_03912 1.8e-69 yxiG
APOCAHHA_03913 1.1e-75
APOCAHHA_03914 4.7e-94 S Protein of unknown function (DUF4240)
APOCAHHA_03915 1.9e-118
APOCAHHA_03916 0.0 wapA M COG3209 Rhs family protein
APOCAHHA_03917 2.4e-159 yxxF EG EamA-like transporter family
APOCAHHA_03918 1.1e-125 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APOCAHHA_03919 2.1e-121 1.14.11.45 E 2OG-Fe dioxygenase
APOCAHHA_03920 2.3e-70 yxiE T Belongs to the universal stress protein A family
APOCAHHA_03921 4.1e-275 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APOCAHHA_03922 1.4e-307 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APOCAHHA_03923 1.7e-31
APOCAHHA_03924 2.4e-133 S nuclease activity
APOCAHHA_03925 4.7e-39 yxiC S Family of unknown function (DUF5344)
APOCAHHA_03926 2.1e-21 S Domain of unknown function (DUF5082)
APOCAHHA_03927 1.1e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
APOCAHHA_03929 8.5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
APOCAHHA_03930 1.1e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
APOCAHHA_03931 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
APOCAHHA_03932 3.5e-233 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
APOCAHHA_03933 3.8e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
APOCAHHA_03934 4.9e-260 lysP E amino acid
APOCAHHA_03935 6.1e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
APOCAHHA_03936 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APOCAHHA_03937 2.5e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APOCAHHA_03938 6.7e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APOCAHHA_03939 2.9e-102 yxxB S Domain of Unknown Function (DUF1206)
APOCAHHA_03940 3.3e-30 yxxB S Domain of Unknown Function (DUF1206)
APOCAHHA_03941 2.9e-183 eutH E Ethanolamine utilisation protein, EutH
APOCAHHA_03942 1.3e-241 yxeQ S MmgE/PrpD family
APOCAHHA_03943 4.4e-211 yxeP 3.5.1.47 E hydrolase activity
APOCAHHA_03944 2.5e-130 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
APOCAHHA_03945 3.3e-113 yxeN P COG0765 ABC-type amino acid transport system, permease component
APOCAHHA_03946 5.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
APOCAHHA_03947 1.2e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOCAHHA_03948 8.6e-251 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APOCAHHA_03949 2e-172 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
APOCAHHA_03950 5.8e-149 yidA S hydrolases of the HAD superfamily
APOCAHHA_03953 3.1e-17 yxeE
APOCAHHA_03954 2.8e-15 yxeD
APOCAHHA_03955 1.9e-68
APOCAHHA_03956 6.2e-174 fhuD P ABC transporter
APOCAHHA_03957 1.7e-57 yxeA S Protein of unknown function (DUF1093)
APOCAHHA_03958 0.0 yxdM V ABC transporter (permease)
APOCAHHA_03959 2.3e-139 yxdL V ABC transporter, ATP-binding protein
APOCAHHA_03960 4.6e-177 T PhoQ Sensor
APOCAHHA_03961 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_03962 4.3e-158 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
APOCAHHA_03963 4.4e-136 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
APOCAHHA_03964 7.3e-166 iolH G Xylose isomerase-like TIM barrel
APOCAHHA_03965 1.8e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
APOCAHHA_03966 2.7e-228 iolF EGP Major facilitator Superfamily
APOCAHHA_03967 1.1e-172 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
APOCAHHA_03968 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
APOCAHHA_03969 1e-176 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
APOCAHHA_03970 1.2e-149 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
APOCAHHA_03971 1.7e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APOCAHHA_03972 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
APOCAHHA_03973 1.2e-174 iolS C Aldo keto reductase
APOCAHHA_03975 1.6e-46 yxcD S Protein of unknown function (DUF2653)
APOCAHHA_03976 2.1e-10 yxcD S Protein of unknown function (DUF2653)
APOCAHHA_03978 4.7e-89 S CGNR zinc finger
APOCAHHA_03979 2.3e-79 T HPP family
APOCAHHA_03980 1.1e-243 csbC EGP Major facilitator Superfamily
APOCAHHA_03981 0.0 htpG O Molecular chaperone. Has ATPase activity
APOCAHHA_03983 1.3e-148 IQ Enoyl-(Acyl carrier protein) reductase
APOCAHHA_03984 1e-199 yxbF K Bacterial regulatory proteins, tetR family
APOCAHHA_03985 1.9e-242 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
APOCAHHA_03986 6.7e-33 yxaI S membrane protein domain
APOCAHHA_03987 2.8e-78 S PQQ-like domain
APOCAHHA_03988 3.1e-61 S Family of unknown function (DUF5391)
APOCAHHA_03989 1.2e-71 yxaI S membrane protein domain
APOCAHHA_03990 1.7e-213 P Protein of unknown function (DUF418)
APOCAHHA_03991 4.6e-188 yxaG 1.13.11.24 S AraC-like ligand binding domain
APOCAHHA_03992 3.1e-96 yxaF K Transcriptional regulator
APOCAHHA_03993 1.9e-195 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APOCAHHA_03994 2.9e-67 yxaD K helix_turn_helix multiple antibiotic resistance protein
APOCAHHA_03995 2.5e-46 S LrgA family
APOCAHHA_03996 5.5e-116 yxaC M effector of murein hydrolase
APOCAHHA_03997 3e-41 S Protein of unknown function (DUF1433)
APOCAHHA_03998 9.3e-28 S Protein of unknown function (DUF1433)
APOCAHHA_03999 4.3e-251 I Pfam Lipase (class 3)
APOCAHHA_04000 1.6e-54
APOCAHHA_04001 7.4e-209 nhaS2 P Sodium/hydrogen exchanger family
APOCAHHA_04002 9.2e-192 yxaB GM Polysaccharide pyruvyl transferase
APOCAHHA_04003 9.2e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
APOCAHHA_04004 3.1e-125 gntR K transcriptional
APOCAHHA_04005 8.3e-298 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
APOCAHHA_04006 2.9e-230 gntP EG COG2610 H gluconate symporter and related permeases
APOCAHHA_04007 5e-265 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APOCAHHA_04008 5.1e-104 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
APOCAHHA_04009 6.1e-285 ahpF O Alkyl hydroperoxide reductase
APOCAHHA_04013 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
APOCAHHA_04014 1.2e-36 KT phosphorelay signal transduction system
APOCAHHA_04015 3.1e-195 mutL 2.1.1.37 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
APOCAHHA_04016 1e-69 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
APOCAHHA_04017 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APOCAHHA_04018 1.1e-09 S YyzF-like protein
APOCAHHA_04019 2.7e-20
APOCAHHA_04020 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APOCAHHA_04022 1.7e-30 yycQ S Protein of unknown function (DUF2651)
APOCAHHA_04023 2.7e-200 yycP
APOCAHHA_04024 5.6e-127 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
APOCAHHA_04025 9.5e-46 yycN 2.3.1.128 K Acetyltransferase
APOCAHHA_04026 1.2e-23 yycN 2.3.1.128 K Acetyltransferase
APOCAHHA_04027 3.6e-186 S aspartate phosphatase
APOCAHHA_04029 2.6e-166 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
APOCAHHA_04030 4.1e-259 rocE E amino acid
APOCAHHA_04031 4.7e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
APOCAHHA_04032 6.6e-254 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
APOCAHHA_04033 4.8e-170 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
APOCAHHA_04034 3.1e-95 K PFAM response regulator receiver
APOCAHHA_04035 8.8e-74 S Peptidase propeptide and YPEB domain
APOCAHHA_04036 2.7e-32 S Peptidase propeptide and YPEB domain
APOCAHHA_04037 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APOCAHHA_04038 7.4e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
APOCAHHA_04039 2.4e-153 yycI S protein conserved in bacteria
APOCAHHA_04040 7.8e-255 yycH S protein conserved in bacteria
APOCAHHA_04041 0.0 vicK 2.7.13.3 T Histidine kinase
APOCAHHA_04042 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APOCAHHA_04047 1.6e-246 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APOCAHHA_04048 1.1e-69 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOCAHHA_04049 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
APOCAHHA_04050 6.2e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
APOCAHHA_04052 1.9e-15 yycC K YycC-like protein
APOCAHHA_04053 3.1e-190 yeaN P COG2807 Cyanate permease
APOCAHHA_04054 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APOCAHHA_04055 2.2e-73 rplI J binds to the 23S rRNA
APOCAHHA_04056 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
APOCAHHA_04057 2.5e-156 yybS S membrane
APOCAHHA_04059 4.7e-82 cotF M Spore coat protein
APOCAHHA_04060 4.9e-66 ydeP3 K Transcriptional regulator
APOCAHHA_04061 7.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
APOCAHHA_04062 1.3e-57
APOCAHHA_04064 6.3e-238 yybO G COG0477 Permeases of the major facilitator superfamily
APOCAHHA_04065 1.1e-109 K TipAS antibiotic-recognition domain
APOCAHHA_04066 5.8e-122
APOCAHHA_04067 3.8e-66 yybH S SnoaL-like domain
APOCAHHA_04068 6e-117 yybG S Pentapeptide repeat-containing protein
APOCAHHA_04069 4.4e-212 ynfM EGP Major facilitator Superfamily
APOCAHHA_04070 1.8e-159 yybE K Transcriptional regulator
APOCAHHA_04071 2.2e-73 yjcF S Acetyltransferase (GNAT) domain
APOCAHHA_04072 8.9e-73 yybC
APOCAHHA_04073 4.4e-123 S Metallo-beta-lactamase superfamily
APOCAHHA_04074 3.6e-76 yybA 2.3.1.57 K transcriptional
APOCAHHA_04075 2.9e-78 yjcF S Acetyltransferase (GNAT) domain
APOCAHHA_04076 1.1e-99 yyaS S Membrane
APOCAHHA_04077 1.1e-99 yyaR K Acetyltransferase (GNAT) domain
APOCAHHA_04078 2e-61 yyaQ S YjbR
APOCAHHA_04079 1.6e-105 yyaP 1.5.1.3 H RibD C-terminal domain
APOCAHHA_04080 6.3e-59 yyaN K MerR HTH family regulatory protein
APOCAHHA_04081 7.7e-158 yyaM EG EamA-like transporter family
APOCAHHA_04082 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
APOCAHHA_04083 3e-162 yyaK S CAAX protease self-immunity
APOCAHHA_04084 5.5e-237 EGP Major facilitator superfamily
APOCAHHA_04085 1.5e-92 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
APOCAHHA_04086 2.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOCAHHA_04087 8.9e-170 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
APOCAHHA_04088 3.9e-139 xth 3.1.11.2 L exodeoxyribonuclease III
APOCAHHA_04089 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APOCAHHA_04090 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APOCAHHA_04091 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
APOCAHHA_04092 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APOCAHHA_04093 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOCAHHA_04094 6.6e-33 yyzM S protein conserved in bacteria
APOCAHHA_04095 1.7e-177 yyaD S Membrane
APOCAHHA_04096 3.1e-110 yyaC S Sporulation protein YyaC
APOCAHHA_04097 1e-148 spo0J K Belongs to the ParB family
APOCAHHA_04098 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
APOCAHHA_04099 2.6e-71 S Bacterial PH domain
APOCAHHA_04100 2.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
APOCAHHA_04101 1.8e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
APOCAHHA_04102 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APOCAHHA_04103 3.5e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APOCAHHA_04104 1.1e-102 jag S single-stranded nucleic acid binding R3H
APOCAHHA_04105 5.1e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APOCAHHA_04106 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APOCAHHA_04107 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APOCAHHA_04108 1.4e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APOCAHHA_04109 2.4e-33 yaaA S S4 domain
APOCAHHA_04110 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APOCAHHA_04111 1.8e-37 yaaB S Domain of unknown function (DUF370)
APOCAHHA_04112 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APOCAHHA_04113 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APOCAHHA_04114 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_04117 3.4e-177 yaaC S YaaC-like Protein
APOCAHHA_04118 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
APOCAHHA_04119 2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
APOCAHHA_04120 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
APOCAHHA_04121 3.4e-106 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
APOCAHHA_04122 5.6e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APOCAHHA_04123 1.3e-09
APOCAHHA_04124 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
APOCAHHA_04125 2.5e-112 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
APOCAHHA_04126 9.4e-190 yaaH M Glycoside Hydrolase Family
APOCAHHA_04127 3.6e-94 yaaI Q COG1335 Amidases related to nicotinamidase
APOCAHHA_04128 4.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APOCAHHA_04129 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APOCAHHA_04130 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APOCAHHA_04131 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APOCAHHA_04132 2.3e-31 yaaL S Protein of unknown function (DUF2508)
APOCAHHA_04133 1.1e-35 bofA S Sigma-K factor-processing regulatory protein BofA
APOCAHHA_04134 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_04137 8.4e-30 csfB S Inhibitor of sigma-G Gin
APOCAHHA_04138 2.1e-98 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
APOCAHHA_04139 2.3e-199 yaaN P Belongs to the TelA family
APOCAHHA_04140 4.3e-264 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
APOCAHHA_04141 8.4e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APOCAHHA_04142 2.2e-54 yaaQ S protein conserved in bacteria
APOCAHHA_04143 1.7e-70 yaaR S protein conserved in bacteria
APOCAHHA_04144 2.7e-177 holB 2.7.7.7 L DNA polymerase III
APOCAHHA_04145 6.1e-146 yaaT S stage 0 sporulation protein
APOCAHHA_04146 4.8e-31 yabA L Involved in initiation control of chromosome replication
APOCAHHA_04147 5.1e-136 yabB 2.1.1.223 S Conserved hypothetical protein 95
APOCAHHA_04148 1.6e-48 yazA L endonuclease containing a URI domain
APOCAHHA_04149 3.8e-146 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APOCAHHA_04150 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
APOCAHHA_04151 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APOCAHHA_04152 1.2e-143 tatD L hydrolase, TatD
APOCAHHA_04153 4.3e-178 rpfB GH23 T protein conserved in bacteria
APOCAHHA_04154 1.5e-95 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APOCAHHA_04155 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APOCAHHA_04156 4e-135 yabG S peptidase
APOCAHHA_04157 7.8e-39 veg S protein conserved in bacteria
APOCAHHA_04158 6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APOCAHHA_04159 4.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
APOCAHHA_04160 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
APOCAHHA_04161 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
APOCAHHA_04162 2.8e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APOCAHHA_04163 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APOCAHHA_04164 3.7e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
APOCAHHA_04165 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APOCAHHA_04166 2.4e-39 yabK S Peptide ABC transporter permease
APOCAHHA_04167 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APOCAHHA_04168 1.6e-91 spoVT K stage V sporulation protein
APOCAHHA_04169 4e-279 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APOCAHHA_04170 4e-241 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
APOCAHHA_04171 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
APOCAHHA_04172 1.5e-49 yabP S Sporulation protein YabP
APOCAHHA_04173 1.1e-102 yabQ S spore cortex biosynthesis protein
APOCAHHA_04174 5.6e-46 divIC D Septum formation initiator
APOCAHHA_04175 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
APOCAHHA_04178 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
APOCAHHA_04179 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
APOCAHHA_04180 4.3e-84 KLT serine threonine protein kinase
APOCAHHA_04181 5.1e-82 KLT serine threonine protein kinase
APOCAHHA_04182 1.1e-267 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APOCAHHA_04183 6.7e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APOCAHHA_04184 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APOCAHHA_04185 4.4e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
APOCAHHA_04186 4.2e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APOCAHHA_04187 1.3e-157 yacD 5.2.1.8 O peptidyl-prolyl isomerase
APOCAHHA_04188 9.8e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APOCAHHA_04189 1.5e-264 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APOCAHHA_04190 8.1e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
APOCAHHA_04191 2.9e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
APOCAHHA_04192 7.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
APOCAHHA_04193 2.9e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APOCAHHA_04194 2.8e-85 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APOCAHHA_04195 1.2e-29 yazB K transcriptional
APOCAHHA_04196 2.7e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APOCAHHA_04197 1.2e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
APOCAHHA_04198 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_04199 3.4e-39 S COG NOG14552 non supervised orthologous group
APOCAHHA_04204 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)