ORF_ID e_value Gene_name EC_number CAZy COGs Description
AACDMEEK_00001 7.9e-70 yqeG S HAD phosphatase, family IIIA
AACDMEEK_00002 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AACDMEEK_00003 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AACDMEEK_00004 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AACDMEEK_00005 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AACDMEEK_00006 3.3e-108 dnaI L Primosomal protein DnaI
AACDMEEK_00007 2.8e-79 dnaB L replication initiation and membrane attachment
AACDMEEK_00008 5.9e-09 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AACDMEEK_00009 3.5e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AACDMEEK_00010 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AACDMEEK_00011 5.6e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AACDMEEK_00012 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AACDMEEK_00013 6.7e-69 ybhL S Belongs to the BI1 family
AACDMEEK_00014 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
AACDMEEK_00015 2.9e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AACDMEEK_00016 2.6e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
AACDMEEK_00017 6.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AACDMEEK_00018 6.8e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AACDMEEK_00019 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AACDMEEK_00020 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
AACDMEEK_00021 3.8e-72 ecsB U ABC transporter
AACDMEEK_00022 2.8e-94 ecsA V ABC transporter, ATP-binding protein
AACDMEEK_00023 5.4e-53 hit FG histidine triad
AACDMEEK_00025 4.3e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AACDMEEK_00026 8.6e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
AACDMEEK_00027 3.3e-21 yheA S Belongs to the UPF0342 family
AACDMEEK_00028 2.3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AACDMEEK_00030 9e-87 ykuT M mechanosensitive ion channel
AACDMEEK_00031 1.6e-176 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AACDMEEK_00032 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AACDMEEK_00033 4.5e-45 ykuL S CBS domain
AACDMEEK_00034 5.7e-119 gla U Major intrinsic protein
AACDMEEK_00035 1.4e-303 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AACDMEEK_00036 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
AACDMEEK_00037 8.6e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AACDMEEK_00038 9.3e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AACDMEEK_00039 1e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
AACDMEEK_00040 1e-124 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AACDMEEK_00041 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
AACDMEEK_00042 3e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AACDMEEK_00043 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AACDMEEK_00044 8.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AACDMEEK_00045 5.5e-98 IQ reductase
AACDMEEK_00046 3e-101 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AACDMEEK_00047 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AACDMEEK_00048 2.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AACDMEEK_00049 4.2e-61 marR K Transcriptional regulator, MarR family
AACDMEEK_00050 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AACDMEEK_00051 3e-36
AACDMEEK_00053 1.5e-81 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
AACDMEEK_00054 5.5e-119 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AACDMEEK_00055 1.3e-61 casE S CRISPR_assoc
AACDMEEK_00056 2.8e-59 casD S CRISPR-associated protein (Cas_Cas5)
AACDMEEK_00057 7.4e-112 casC L CT1975-like protein
AACDMEEK_00058 1.4e-21 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
AACDMEEK_00059 1.5e-151 casA L the current gene model (or a revised gene model) may contain a frame shift
AACDMEEK_00060 3.6e-259 cas3 L CRISPR-associated helicase cas3
AACDMEEK_00061 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
AACDMEEK_00062 1.9e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AACDMEEK_00063 5.6e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AACDMEEK_00064 8.3e-187 ytgP S Polysaccharide biosynthesis protein
AACDMEEK_00065 2.4e-192 cycA E Amino acid permease
AACDMEEK_00066 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AACDMEEK_00067 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AACDMEEK_00077 2.1e-07
AACDMEEK_00087 8.8e-50 yugI 5.3.1.9 J general stress protein
AACDMEEK_00088 3.6e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AACDMEEK_00089 3e-92 dedA S SNARE associated Golgi protein
AACDMEEK_00090 6e-32 S Protein of unknown function (DUF1461)
AACDMEEK_00091 7.5e-114 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AACDMEEK_00092 1.9e-53 yutD S Protein of unknown function (DUF1027)
AACDMEEK_00093 1.1e-56 S Calcineurin-like phosphoesterase
AACDMEEK_00094 9.3e-184 cycA E Amino acid permease
AACDMEEK_00095 2e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
AACDMEEK_00097 9.4e-11 S Putative Competence protein ComGF
AACDMEEK_00099 1.9e-13
AACDMEEK_00100 3.6e-27 comGC U competence protein ComGC
AACDMEEK_00101 1.7e-97 comGB NU type II secretion system
AACDMEEK_00102 1.1e-120 comGA NU Type II IV secretion system protein
AACDMEEK_00103 1.8e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AACDMEEK_00104 5.1e-120 yebC K Transcriptional regulatory protein
AACDMEEK_00105 3.7e-42 S VanZ like family
AACDMEEK_00106 5e-158 ccpA K catabolite control protein A
AACDMEEK_00107 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AACDMEEK_00108 3.9e-14
AACDMEEK_00111 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AACDMEEK_00112 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
AACDMEEK_00113 2.3e-65 hly S protein, hemolysin III
AACDMEEK_00114 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
AACDMEEK_00115 9.4e-84 S membrane
AACDMEEK_00116 1.1e-79 S VIT family
AACDMEEK_00117 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
AACDMEEK_00118 2.7e-56 P Plays a role in the regulation of phosphate uptake
AACDMEEK_00119 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AACDMEEK_00120 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AACDMEEK_00121 3.9e-122 pstA P Phosphate transport system permease protein PstA
AACDMEEK_00122 5.4e-119 pstC P probably responsible for the translocation of the substrate across the membrane
AACDMEEK_00123 1.4e-97 pstS P Phosphate
AACDMEEK_00124 3.9e-41 yjbH Q Thioredoxin
AACDMEEK_00125 4e-230 pepF E oligoendopeptidase F
AACDMEEK_00126 1.5e-68 coiA 3.6.4.12 S Competence protein
AACDMEEK_00127 4e-46 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AACDMEEK_00128 9.1e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
AACDMEEK_00134 5.1e-08
AACDMEEK_00143 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AACDMEEK_00144 2e-25 ykuJ S Protein of unknown function (DUF1797)
AACDMEEK_00145 1.7e-126 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AACDMEEK_00146 1.7e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
AACDMEEK_00147 6.7e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
AACDMEEK_00148 4.5e-284 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AACDMEEK_00149 9.7e-37 ptsH G phosphocarrier protein HPR
AACDMEEK_00150 2.6e-15
AACDMEEK_00151 0.0 clpE O Belongs to the ClpA ClpB family
AACDMEEK_00152 3.9e-23 XK27_09445 S Domain of unknown function (DUF1827)
AACDMEEK_00153 4.5e-106 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
AACDMEEK_00154 8.9e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AACDMEEK_00155 2.3e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AACDMEEK_00156 1.9e-157 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AACDMEEK_00157 1.7e-90 yueF S AI-2E family transporter
AACDMEEK_00158 2.6e-97 ygaC J Belongs to the UPF0374 family
AACDMEEK_00159 8.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AACDMEEK_00160 5e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
AACDMEEK_00161 1.8e-19 sigH K DNA-templated transcription, initiation
AACDMEEK_00162 2.7e-22 S Cytochrome B5
AACDMEEK_00163 6.6e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
AACDMEEK_00164 3.8e-59
AACDMEEK_00165 6.9e-42 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AACDMEEK_00166 2.5e-155 nrnB S DHHA1 domain
AACDMEEK_00167 3.3e-91 yunF F Protein of unknown function DUF72
AACDMEEK_00168 4.5e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
AACDMEEK_00169 5.4e-13
AACDMEEK_00170 2.4e-145 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AACDMEEK_00171 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AACDMEEK_00172 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AACDMEEK_00173 7.7e-178 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AACDMEEK_00174 2.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
AACDMEEK_00175 1.6e-180 pbuG S permease
AACDMEEK_00176 3.9e-160 L transposase, IS605 OrfB family
AACDMEEK_00177 2.8e-57 tlpA2 L Transposase IS200 like
AACDMEEK_00186 2.4e-251 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
AACDMEEK_00187 1.6e-61
AACDMEEK_00188 3.6e-41 rpmE2 J Ribosomal protein L31
AACDMEEK_00189 9e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AACDMEEK_00190 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AACDMEEK_00192 2.5e-289 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AACDMEEK_00193 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AACDMEEK_00194 1.8e-32 ywiB S Domain of unknown function (DUF1934)
AACDMEEK_00195 3.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
AACDMEEK_00196 7.3e-205 ywfO S HD domain protein
AACDMEEK_00197 5.2e-89 S hydrolase
AACDMEEK_00198 1e-101 ydcZ S Putative inner membrane exporter, YdcZ
AACDMEEK_00199 1.3e-22
AACDMEEK_00200 4.9e-71
AACDMEEK_00202 3.2e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
AACDMEEK_00203 7.8e-23
AACDMEEK_00204 1.1e-55 spoVK O ATPase family associated with various cellular activities (AAA)
AACDMEEK_00206 9.9e-87 S overlaps another CDS with the same product name
AACDMEEK_00207 2.1e-125 S overlaps another CDS with the same product name
AACDMEEK_00208 5e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AACDMEEK_00209 1.5e-62 bCE_4747 S Beta-lactamase superfamily domain
AACDMEEK_00210 1.4e-290 ybiT S ABC transporter, ATP-binding protein
AACDMEEK_00211 1e-78 2.4.2.3 F Phosphorylase superfamily
AACDMEEK_00212 1.7e-24
AACDMEEK_00213 9e-113 dkg S reductase
AACDMEEK_00214 7e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AACDMEEK_00215 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AACDMEEK_00216 2.3e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AACDMEEK_00217 8.6e-48 EGP Transmembrane secretion effector
AACDMEEK_00218 3.1e-137 purR 2.4.2.7 F pur operon repressor
AACDMEEK_00220 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AACDMEEK_00221 8.9e-102 pfoS S Phosphotransferase system, EIIC
AACDMEEK_00222 2e-127 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AACDMEEK_00223 1.2e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
AACDMEEK_00224 4.2e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AACDMEEK_00225 1.7e-201 argH 4.3.2.1 E argininosuccinate lyase
AACDMEEK_00226 2.1e-156 amtB P ammonium transporter
AACDMEEK_00227 4e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AACDMEEK_00228 6.6e-46 argR K Regulates arginine biosynthesis genes
AACDMEEK_00229 4.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
AACDMEEK_00230 1.9e-91 S Alpha/beta hydrolase of unknown function (DUF915)
AACDMEEK_00231 9.2e-23 veg S Biofilm formation stimulator VEG
AACDMEEK_00232 1.6e-131 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AACDMEEK_00233 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AACDMEEK_00234 5.9e-103 tatD L hydrolase, TatD family
AACDMEEK_00235 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AACDMEEK_00236 3.9e-128
AACDMEEK_00237 7.9e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AACDMEEK_00238 1.6e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
AACDMEEK_00239 2.3e-31 K Transcriptional regulator
AACDMEEK_00240 1.3e-103 ybhR V ABC transporter
AACDMEEK_00241 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
AACDMEEK_00242 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
AACDMEEK_00243 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
AACDMEEK_00244 2.7e-127 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AACDMEEK_00245 1.2e-271 helD 3.6.4.12 L DNA helicase
AACDMEEK_00247 1.3e-114 htpX O Belongs to the peptidase M48B family
AACDMEEK_00248 8.7e-72 lemA S LemA family
AACDMEEK_00249 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
AACDMEEK_00250 8.4e-46 yjcF K protein acetylation
AACDMEEK_00252 1.5e-253 yfiC V ABC transporter
AACDMEEK_00253 4.4e-223 lmrA V ABC transporter, ATP-binding protein
AACDMEEK_00254 4.5e-35 K Bacterial regulatory proteins, tetR family
AACDMEEK_00255 4.4e-243 yhcA V ABC transporter, ATP-binding protein
AACDMEEK_00256 7.7e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AACDMEEK_00257 3.9e-146 G Transporter, major facilitator family protein
AACDMEEK_00258 8.5e-90 lacX 5.1.3.3 G Aldose 1-epimerase
AACDMEEK_00259 7.4e-142 hpk31 2.7.13.3 T Histidine kinase
AACDMEEK_00260 2.5e-113 K response regulator
AACDMEEK_00261 8e-91 patB 4.4.1.8 E Aminotransferase, class I
AACDMEEK_00262 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
AACDMEEK_00263 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AACDMEEK_00264 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AACDMEEK_00265 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AACDMEEK_00266 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
AACDMEEK_00267 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AACDMEEK_00268 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AACDMEEK_00269 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AACDMEEK_00270 1.6e-55 ctsR K Belongs to the CtsR family
AACDMEEK_00272 6.6e-120 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AACDMEEK_00273 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AACDMEEK_00274 9.8e-160 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AACDMEEK_00275 2.1e-185 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AACDMEEK_00276 7.5e-132 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AACDMEEK_00288 2.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AACDMEEK_00289 2.7e-242 lysP E amino acid
AACDMEEK_00290 5.2e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
AACDMEEK_00291 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AACDMEEK_00292 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AACDMEEK_00293 9.4e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
AACDMEEK_00294 4.5e-83 lysR5 K LysR substrate binding domain
AACDMEEK_00295 2.9e-119 yxaA S membrane transporter protein
AACDMEEK_00296 2.6e-32 ywjH S Protein of unknown function (DUF1634)
AACDMEEK_00297 1.2e-117 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AACDMEEK_00298 3.5e-226 pipD E Dipeptidase
AACDMEEK_00299 6.8e-21 K helix_turn_helix multiple antibiotic resistance protein
AACDMEEK_00300 4.4e-165 EGP Major facilitator Superfamily
AACDMEEK_00301 5.6e-82 S L,D-transpeptidase catalytic domain
AACDMEEK_00302 6e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
AACDMEEK_00303 5.1e-145 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AACDMEEK_00304 7.2e-27 ydiI Q Thioesterase superfamily
AACDMEEK_00305 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
AACDMEEK_00306 9.6e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
AACDMEEK_00307 2.4e-113 degV S EDD domain protein, DegV family
AACDMEEK_00308 4.2e-224 cadA P P-type ATPase
AACDMEEK_00309 6.9e-254 E Amino acid permease
AACDMEEK_00310 6e-83 S Membrane
AACDMEEK_00311 2.9e-48 cps3F
AACDMEEK_00312 1.3e-303 fruA 2.7.1.202 GT Phosphotransferase System
AACDMEEK_00313 4.5e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AACDMEEK_00314 3.8e-86 fruR K DeoR C terminal sensor domain
AACDMEEK_00315 3e-219 XK27_08635 S UPF0210 protein
AACDMEEK_00316 4.1e-27 gcvR T Belongs to the UPF0237 family
AACDMEEK_00317 6.1e-39
AACDMEEK_00318 2.4e-76 E GDSL-like Lipase/Acylhydrolase family
AACDMEEK_00319 7.1e-56 S Protein of unknown function (DUF975)
AACDMEEK_00320 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
AACDMEEK_00321 3e-230 lpdA 1.8.1.4 C Dehydrogenase
AACDMEEK_00322 1.2e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AACDMEEK_00323 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
AACDMEEK_00324 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
AACDMEEK_00325 6.5e-07 M domain protein
AACDMEEK_00327 5.7e-55 S Protein of unknown function (DUF4256)
AACDMEEK_00328 7.4e-128 metQ M Belongs to the nlpA lipoprotein family
AACDMEEK_00329 8.3e-32 metI U ABC transporter permease
AACDMEEK_00330 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AACDMEEK_00332 1.9e-60 L Transposase-like protein
AACDMEEK_00333 1.3e-74 3.1.21.3 V Type I restriction modification DNA specificity domain
AACDMEEK_00334 5.3e-138 L Belongs to the 'phage' integrase family
AACDMEEK_00335 7.4e-66 3.1.21.3 V Type I restriction modification DNA specificity domain
AACDMEEK_00336 3.3e-241 hsdM 2.1.1.72 V PFAM N-6 DNA methylase
AACDMEEK_00337 2.5e-95 3.1.21.3 V PFAM restriction modification system DNA specificity domain
AACDMEEK_00338 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
AACDMEEK_00339 6.9e-48 3.1.21.3 V Type I restriction modification DNA specificity domain
AACDMEEK_00340 3.3e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
AACDMEEK_00341 3.1e-171 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AACDMEEK_00342 1.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
AACDMEEK_00343 5.1e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
AACDMEEK_00344 1.7e-82 drgA C nitroreductase
AACDMEEK_00345 4.4e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
AACDMEEK_00346 1e-69 metI P ABC transporter permease
AACDMEEK_00347 8.9e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AACDMEEK_00348 1.6e-109 metQ1 P Belongs to the nlpA lipoprotein family
AACDMEEK_00349 2.7e-144 E methionine synthase, vitamin-B12 independent
AACDMEEK_00350 7.5e-102 pgm3 G phosphoglycerate mutase
AACDMEEK_00351 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AACDMEEK_00352 1.9e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AACDMEEK_00353 5.9e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AACDMEEK_00354 1.1e-67 M ErfK YbiS YcfS YnhG
AACDMEEK_00355 5.2e-107 XK27_08845 S ABC transporter, ATP-binding protein
AACDMEEK_00356 1.6e-112 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
AACDMEEK_00357 1.6e-132 ABC-SBP S ABC transporter
AACDMEEK_00358 1.3e-159 potD P ABC transporter
AACDMEEK_00359 4.9e-103 potC U Binding-protein-dependent transport system inner membrane component
AACDMEEK_00360 1.1e-120 potB P ABC transporter permease
AACDMEEK_00361 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AACDMEEK_00362 9.6e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AACDMEEK_00363 3.7e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
AACDMEEK_00364 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AACDMEEK_00365 6.7e-13 S Enterocin A Immunity
AACDMEEK_00367 2.2e-16 pspC KT PspC domain
AACDMEEK_00368 3.1e-16 S Putative adhesin
AACDMEEK_00369 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
AACDMEEK_00370 8.1e-38 K transcriptional regulator PadR family
AACDMEEK_00371 1.5e-46 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
AACDMEEK_00372 2e-74 ung2 3.2.2.27 L Uracil-DNA glycosylase
AACDMEEK_00373 8.4e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AACDMEEK_00374 1.8e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AACDMEEK_00375 3.5e-70 mltD CBM50 M NlpC P60 family protein
AACDMEEK_00376 3.2e-52 manO S Domain of unknown function (DUF956)
AACDMEEK_00377 1.6e-147 manN G system, mannose fructose sorbose family IID component
AACDMEEK_00378 6.4e-116 manY G PTS system sorbose-specific iic component
AACDMEEK_00379 5.3e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AACDMEEK_00380 1.8e-80 rbsB G sugar-binding domain protein
AACDMEEK_00381 1.4e-99 baeS T Histidine kinase
AACDMEEK_00382 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
AACDMEEK_00383 2.4e-120 G Bacterial extracellular solute-binding protein
AACDMEEK_00384 1.6e-70 S Protein of unknown function (DUF554)
AACDMEEK_00385 5.1e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AACDMEEK_00386 1.6e-31 merR K MerR HTH family regulatory protein
AACDMEEK_00387 7.9e-197 lmrB EGP Major facilitator Superfamily
AACDMEEK_00388 1.8e-34 S Domain of unknown function (DUF4811)
AACDMEEK_00389 2.8e-84 G Phosphoglycerate mutase family
AACDMEEK_00390 2.9e-60 yceE S haloacid dehalogenase-like hydrolase
AACDMEEK_00391 2.6e-74 glcR K DeoR C terminal sensor domain
AACDMEEK_00392 8.2e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AACDMEEK_00393 1.5e-52 bioY S BioY family
AACDMEEK_00394 1.4e-94 S Predicted membrane protein (DUF2207)
AACDMEEK_00395 1.4e-19
AACDMEEK_00396 2e-37 2.7.8.12 GT2 V Glycosyl transferase, family 2
AACDMEEK_00397 1.3e-53 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
AACDMEEK_00398 9.7e-59 ktrA P TrkA-N domain
AACDMEEK_00399 1.7e-113 ntpJ P Potassium uptake protein
AACDMEEK_00400 5.3e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
AACDMEEK_00401 2.3e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
AACDMEEK_00402 8.2e-218 scrB 3.2.1.26 GH32 G invertase
AACDMEEK_00403 8.6e-147 scrR K helix_turn _helix lactose operon repressor
AACDMEEK_00404 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AACDMEEK_00405 1.8e-209 glnP P ABC transporter
AACDMEEK_00407 1.1e-59 uspA T Universal stress protein family
AACDMEEK_00408 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
AACDMEEK_00409 1.1e-25
AACDMEEK_00410 6.4e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
AACDMEEK_00411 1.8e-109 puuD S peptidase C26
AACDMEEK_00412 1.4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AACDMEEK_00413 7.8e-152 lsa S ABC transporter
AACDMEEK_00414 6.1e-148 mepA V MATE efflux family protein
AACDMEEK_00415 5.3e-45 arbx M family 8
AACDMEEK_00416 1.2e-30 M Glycosyltransferase like family 2
AACDMEEK_00417 2e-38 S glycosyl transferase family 2
AACDMEEK_00418 1.6e-34 cpsJ M Glycosyltransferase group 2 family protein
AACDMEEK_00419 1.5e-36 M family 8
AACDMEEK_00420 1.2e-55 M lipopolysaccharide 3-alpha-galactosyltransferase activity
AACDMEEK_00421 2e-44 arbx M family 8
AACDMEEK_00422 2.8e-68 nss M transferase activity, transferring glycosyl groups
AACDMEEK_00423 2.4e-56 M lipopolysaccharide 3-alpha-galactosyltransferase activity
AACDMEEK_00424 3.9e-110 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AACDMEEK_00425 2.4e-34 yxaB 2.4.1.166 GT2 M Glycosyltransferase like family 2
AACDMEEK_00426 2.6e-36 S glycosyl transferase family 2
AACDMEEK_00427 6.2e-35 M Glycosyltransferase like family 2
AACDMEEK_00428 1.4e-153 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AACDMEEK_00431 1.6e-247 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AACDMEEK_00432 6.6e-32 asp3 S Accessory Sec system protein Asp3
AACDMEEK_00433 3.4e-105 asp2 3.4.11.5 S Accessory Sec system protein Asp2
AACDMEEK_00434 3.1e-90 asp1 S Accessory Sec system protein Asp1
AACDMEEK_00435 1.5e-63 secY2 U SecY translocase
AACDMEEK_00436 7.5e-139 S interspecies interaction between organisms
AACDMEEK_00437 5.5e-208 G glycerol-3-phosphate transporter
AACDMEEK_00438 4e-73 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AACDMEEK_00439 1.1e-144 htrA 3.4.21.107 O serine protease
AACDMEEK_00440 2.4e-115 vicX 3.1.26.11 S domain protein
AACDMEEK_00441 6.6e-73 ebh 2.1.1.80, 3.1.1.61 D interspecies interaction between organisms
AACDMEEK_00442 2.5e-80 yycI S YycH protein
AACDMEEK_00443 3e-102 yycH S YycH protein
AACDMEEK_00444 9.6e-272 vicK 2.7.13.3 T Histidine kinase
AACDMEEK_00445 1.3e-113 K response regulator
AACDMEEK_00446 7.1e-158 lctO C FMN-dependent dehydrogenase
AACDMEEK_00447 1e-170 uhpT EGP Mycoplasma MFS transporter
AACDMEEK_00448 5e-241 V ABC transporter transmembrane region
AACDMEEK_00449 2.8e-217 XK27_09600 V ABC transporter, ATP-binding protein
AACDMEEK_00450 7.1e-32 K Transcriptional regulator, MarR family
AACDMEEK_00451 4e-174 S Putative peptidoglycan binding domain
AACDMEEK_00452 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
AACDMEEK_00453 2.3e-137 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
AACDMEEK_00454 1.9e-23 S dextransucrase activity
AACDMEEK_00455 2.4e-55 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AACDMEEK_00456 9.3e-224 pepF E Oligopeptidase F
AACDMEEK_00457 3.7e-96 yicL EG EamA-like transporter family
AACDMEEK_00458 3.1e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
AACDMEEK_00459 3.5e-167 yjjP S Putative threonine/serine exporter
AACDMEEK_00460 4.8e-109 glcU U sugar transport
AACDMEEK_00461 1.1e-13 yobS K transcriptional regulator
AACDMEEK_00462 4.2e-151 mdtG EGP Major facilitator Superfamily
AACDMEEK_00463 3.4e-105 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AACDMEEK_00464 1.1e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
AACDMEEK_00465 1.3e-231 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AACDMEEK_00466 9.8e-18 yneR
AACDMEEK_00467 8.7e-249 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AACDMEEK_00468 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AACDMEEK_00469 9.6e-12 yiiE S Protein of unknown function (DUF1211)
AACDMEEK_00470 8.1e-35 yiiE S Protein of unknown function (DUF1211)
AACDMEEK_00471 0.0 asnB 6.3.5.4 E Asparagine synthase
AACDMEEK_00472 1.1e-64 D peptidase
AACDMEEK_00473 4.7e-116 S Glycosyl transferase family 2
AACDMEEK_00474 3.3e-159 L transposase, IS605 OrfB family
AACDMEEK_00475 4.3e-58 tlpA2 L Transposase IS200 like
AACDMEEK_00476 5.6e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
AACDMEEK_00477 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AACDMEEK_00478 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AACDMEEK_00479 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
AACDMEEK_00480 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AACDMEEK_00481 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AACDMEEK_00482 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AACDMEEK_00483 9e-20 yaaA S S4 domain protein YaaA
AACDMEEK_00484 1.1e-158 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AACDMEEK_00485 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AACDMEEK_00486 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
AACDMEEK_00487 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AACDMEEK_00488 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AACDMEEK_00489 1.1e-199 nupG F Nucleoside
AACDMEEK_00490 4.4e-122 MA20_14895 S Conserved hypothetical protein 698
AACDMEEK_00491 1.7e-53 K LysR substrate binding domain
AACDMEEK_00492 7.6e-09
AACDMEEK_00493 6e-66 yxkH G Polysaccharide deacetylase
AACDMEEK_00494 4.5e-29 yqkB S Belongs to the HesB IscA family
AACDMEEK_00503 5.1e-08
AACDMEEK_00509 1.4e-06
AACDMEEK_00510 6.7e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AACDMEEK_00511 1.7e-54 rplI J Binds to the 23S rRNA
AACDMEEK_00512 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AACDMEEK_00513 6.9e-64 C FMN binding
AACDMEEK_00514 6.2e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AACDMEEK_00516 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AACDMEEK_00517 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
AACDMEEK_00518 3.9e-11 S CAAX protease self-immunity
AACDMEEK_00519 5.6e-82 S Belongs to the UPF0246 family
AACDMEEK_00520 4.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AACDMEEK_00521 1.7e-130 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
AACDMEEK_00522 2.4e-73 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
AACDMEEK_00523 4.1e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
AACDMEEK_00524 1.3e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
AACDMEEK_00525 2e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
AACDMEEK_00526 3.3e-140 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AACDMEEK_00527 1.3e-79 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
AACDMEEK_00528 5.6e-136 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
AACDMEEK_00529 1.1e-148 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AACDMEEK_00530 2.2e-42 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AACDMEEK_00531 7.4e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AACDMEEK_00532 1.1e-251 ctpA 3.6.3.54 P P-type ATPase
AACDMEEK_00533 6.5e-66 pgm3 G phosphoglycerate mutase family
AACDMEEK_00534 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
AACDMEEK_00535 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AACDMEEK_00536 3.5e-218 yifK E Amino acid permease
AACDMEEK_00537 6.2e-203 oppA E ABC transporter, substratebinding protein
AACDMEEK_00538 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AACDMEEK_00539 1.7e-169 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AACDMEEK_00540 1.3e-180 oppD P Belongs to the ABC transporter superfamily
AACDMEEK_00541 1.3e-155 oppF P Belongs to the ABC transporter superfamily
AACDMEEK_00542 7e-16 psiE S Phosphate-starvation-inducible E
AACDMEEK_00543 3.8e-209 mmuP E amino acid
AACDMEEK_00544 3.4e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
AACDMEEK_00545 4.2e-151 yfeX P Peroxidase
AACDMEEK_00546 7.5e-29 tetR K Transcriptional regulator C-terminal region
AACDMEEK_00547 1.6e-180 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
AACDMEEK_00548 5.8e-21 L An automated process has identified a potential problem with this gene model
AACDMEEK_00549 1.8e-52 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AACDMEEK_00550 6.2e-163 oxlT P Major Facilitator Superfamily
AACDMEEK_00551 3.4e-67 ybbL S ABC transporter
AACDMEEK_00552 2.2e-102 ybbM S Uncharacterised protein family (UPF0014)
AACDMEEK_00554 3.6e-18
AACDMEEK_00555 1.9e-26 aguA_2 3.5.3.12 E Belongs to the agmatine deiminase family
AACDMEEK_00557 9.7e-41 wecD K Acetyltransferase GNAT Family
AACDMEEK_00558 1.1e-46 hmpT S ECF-type riboflavin transporter, S component
AACDMEEK_00559 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
AACDMEEK_00561 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
AACDMEEK_00562 1.8e-286 pepO 3.4.24.71 O Peptidase family M13
AACDMEEK_00563 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
AACDMEEK_00564 9.1e-54 K Transcriptional regulator C-terminal region
AACDMEEK_00565 1.4e-56 jag S R3H domain protein
AACDMEEK_00566 9e-57 ohrR K helix_turn_helix multiple antibiotic resistance protein
AACDMEEK_00567 1.6e-33 azlD S Branched-chain amino acid transport protein (AzlD)
AACDMEEK_00568 2.6e-76 azlC E branched-chain amino acid
AACDMEEK_00569 2.7e-58 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
AACDMEEK_00570 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AACDMEEK_00571 1e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
AACDMEEK_00572 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
AACDMEEK_00573 1.2e-192 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
AACDMEEK_00574 4.1e-75 XK27_02070 S Nitroreductase family
AACDMEEK_00575 1.5e-112 endA F DNA RNA non-specific endonuclease
AACDMEEK_00577 6.5e-209 brnQ U Component of the transport system for branched-chain amino acids
AACDMEEK_00578 6.5e-61 K Bacterial regulatory proteins, tetR family
AACDMEEK_00579 4.6e-113 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
AACDMEEK_00580 2.8e-153 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
AACDMEEK_00581 9.5e-69 dhaL 2.7.1.121 S Dak2
AACDMEEK_00582 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
AACDMEEK_00583 2.9e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AACDMEEK_00584 4.9e-176 yjcE P Sodium proton antiporter
AACDMEEK_00585 6.8e-210 mtlR K Mga helix-turn-helix domain
AACDMEEK_00586 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AACDMEEK_00587 2.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AACDMEEK_00588 3.5e-28 M Glycosyl hydrolases family 25
AACDMEEK_00589 5.9e-30 L Helix-turn-helix domain
AACDMEEK_00590 5.1e-65 L PFAM Integrase catalytic region
AACDMEEK_00591 1.4e-52 M Glycosyl hydrolases family 25
AACDMEEK_00593 4.5e-102 tcyB E ABC transporter
AACDMEEK_00594 2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AACDMEEK_00595 4.8e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
AACDMEEK_00596 1.6e-38 K Transcriptional regulator
AACDMEEK_00597 2.2e-107 terC P Integral membrane protein TerC family
AACDMEEK_00598 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
AACDMEEK_00599 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AACDMEEK_00600 1.9e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
AACDMEEK_00601 1.8e-41 gntR1 K Transcriptional regulator, GntR family
AACDMEEK_00602 2.6e-94 V ABC transporter, ATP-binding protein
AACDMEEK_00603 6.7e-09
AACDMEEK_00604 1.1e-39 ybjQ S Belongs to the UPF0145 family
AACDMEEK_00605 8.1e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
AACDMEEK_00606 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AACDMEEK_00607 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AACDMEEK_00608 4.8e-142 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AACDMEEK_00609 1.4e-33
AACDMEEK_00610 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
AACDMEEK_00611 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AACDMEEK_00612 1.5e-62 srtA 3.4.22.70 M sortase family
AACDMEEK_00614 2.6e-71 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
AACDMEEK_00615 2.3e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
AACDMEEK_00616 0.0 pacL 3.6.3.8 P P-type ATPase
AACDMEEK_00617 2.2e-107 3.1.4.46 C phosphodiesterase
AACDMEEK_00618 4.5e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AACDMEEK_00619 1.8e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
AACDMEEK_00620 4.8e-82 noc K Belongs to the ParB family
AACDMEEK_00621 6.5e-118 soj D Sporulation initiation inhibitor
AACDMEEK_00622 4.1e-108 spo0J K Belongs to the ParB family
AACDMEEK_00623 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
AACDMEEK_00624 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AACDMEEK_00625 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
AACDMEEK_00626 1.7e-92 S Bacterial membrane protein, YfhO
AACDMEEK_00627 1.3e-59 I Alpha/beta hydrolase family
AACDMEEK_00629 1.4e-46 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
AACDMEEK_00630 3.4e-38
AACDMEEK_00631 1.3e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
AACDMEEK_00632 9.1e-100 fhuC P ABC transporter
AACDMEEK_00633 2.8e-95 znuB U ABC 3 transport family
AACDMEEK_00634 1.5e-55 S ECF transporter, substrate-specific component
AACDMEEK_00635 7.5e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AACDMEEK_00636 1.9e-91 S NADPH-dependent FMN reductase
AACDMEEK_00637 2.4e-28 yraB K transcriptional regulator
AACDMEEK_00638 1.2e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
AACDMEEK_00640 5.8e-154 EGP Major facilitator Superfamily
AACDMEEK_00641 6.6e-58 S Haloacid dehalogenase-like hydrolase
AACDMEEK_00642 1.2e-88 yvyE 3.4.13.9 S YigZ family
AACDMEEK_00643 1.9e-38 S CAAX protease self-immunity
AACDMEEK_00644 8.4e-116 cps1D M Domain of unknown function (DUF4422)
AACDMEEK_00645 5.1e-62 S Glycosyltransferase like family 2
AACDMEEK_00646 5.9e-15 waaB GT4 M Glycosyl transferases group 1
AACDMEEK_00647 2.2e-161 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AACDMEEK_00648 8.9e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AACDMEEK_00650 2.6e-142 L AAA ATPase domain
AACDMEEK_00651 4.4e-117 3.6.4.12 L UvrD/REP helicase N-terminal domain
AACDMEEK_00652 3.1e-96 M Glycosyl transferase family 8
AACDMEEK_00653 3.5e-97 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
AACDMEEK_00654 1.4e-102 4.2.1.46 GM Male sterility protein
AACDMEEK_00655 3e-32 ftsK I transferase activity, transferring acyl groups other than amino-acyl groups
AACDMEEK_00656 9.9e-07 I CDP-alcohol phosphatidyltransferase
AACDMEEK_00657 1.5e-108 M Glycosyl transferases group 1
AACDMEEK_00658 1.2e-107 M transferase activity, transferring glycosyl groups
AACDMEEK_00659 2.6e-22 S EpsG family
AACDMEEK_00660 3.6e-71 epsB M biosynthesis protein
AACDMEEK_00661 1.9e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
AACDMEEK_00662 7.1e-112 ywqE 3.1.3.48 GM PHP domain protein
AACDMEEK_00663 6.3e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AACDMEEK_00664 2.9e-90 rfbP M Bacterial sugar transferase
AACDMEEK_00665 1.1e-113 M Core-2/I-Branching enzyme
AACDMEEK_00666 5.1e-196 glf 5.4.99.9 M UDP-galactopyranose mutase
AACDMEEK_00667 5.9e-189 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
AACDMEEK_00668 2.6e-69 rny D Peptidase family M23
AACDMEEK_00670 3.3e-137 tetA EGP Major facilitator Superfamily
AACDMEEK_00671 1e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
AACDMEEK_00672 9.4e-214 yjeM E Amino Acid
AACDMEEK_00673 5.6e-190 glnPH2 P ABC transporter permease
AACDMEEK_00674 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AACDMEEK_00675 3.1e-43 E lipolytic protein G-D-S-L family
AACDMEEK_00676 3.5e-134 coaA 2.7.1.33 F Pantothenic acid kinase
AACDMEEK_00677 3.4e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AACDMEEK_00678 1.4e-47 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AACDMEEK_00679 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AACDMEEK_00680 2.1e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AACDMEEK_00681 1.5e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AACDMEEK_00682 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
AACDMEEK_00683 5.4e-157 XK27_09615 S reductase
AACDMEEK_00684 4.4e-39 2.7.7.65 T phosphorelay sensor kinase activity
AACDMEEK_00685 1.5e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
AACDMEEK_00686 2e-53 cps3I G Acyltransferase family
AACDMEEK_00687 3.6e-14
AACDMEEK_00688 2.4e-124 S Bacterial membrane protein YfhO
AACDMEEK_00689 1.8e-160 XK27_08315 M Sulfatase
AACDMEEK_00690 8.1e-71 M Domain of unknown function (DUF4422)
AACDMEEK_00691 4.7e-59 cps3F
AACDMEEK_00692 3.3e-88 waaB GT4 M Glycosyl transferases group 1
AACDMEEK_00693 5.7e-63 S Psort location CytoplasmicMembrane, score
AACDMEEK_00694 5.3e-73 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AACDMEEK_00695 2.2e-178 thrC 4.2.3.1 E Threonine synthase
AACDMEEK_00696 2.4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AACDMEEK_00697 7.5e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AACDMEEK_00698 7.3e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AACDMEEK_00699 7.9e-58 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AACDMEEK_00700 9.7e-194 XK27_08315 M Sulfatase
AACDMEEK_00702 2.9e-168 mdtG EGP Major facilitator Superfamily
AACDMEEK_00703 1e-248 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
AACDMEEK_00704 2.8e-83 treR K UTRA
AACDMEEK_00705 7.3e-259 treB G phosphotransferase system
AACDMEEK_00706 4.6e-63 3.1.3.73 G phosphoglycerate mutase
AACDMEEK_00707 1.8e-82 pncA Q isochorismatase
AACDMEEK_00708 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AACDMEEK_00709 5.4e-101 ydhQ K UbiC transcription regulator-associated domain protein
AACDMEEK_00710 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AACDMEEK_00711 1.3e-41 K Transcriptional regulator, HxlR family
AACDMEEK_00712 2.9e-164 C Luciferase-like monooxygenase
AACDMEEK_00713 1.7e-67 1.5.1.38 S NADPH-dependent FMN reductase
AACDMEEK_00714 3.4e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AACDMEEK_00715 3e-76 L haloacid dehalogenase-like hydrolase
AACDMEEK_00716 6.7e-61 EG EamA-like transporter family
AACDMEEK_00717 5.3e-118 K AI-2E family transporter
AACDMEEK_00718 2.2e-173 malY 4.4.1.8 E Aminotransferase, class I
AACDMEEK_00719 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AACDMEEK_00720 3.1e-31 yfjR K WYL domain
AACDMEEK_00721 3.1e-12 yfjR K WYL domain
AACDMEEK_00722 4e-11 S Mor transcription activator family
AACDMEEK_00724 1.4e-08 S zinc-ribbon domain
AACDMEEK_00729 2.8e-95 V domain protein
AACDMEEK_00730 2.9e-119 xth 3.1.11.2 L exodeoxyribonuclease III
AACDMEEK_00731 2e-17
AACDMEEK_00732 1.3e-102 azlC E AzlC protein
AACDMEEK_00733 1.3e-38 azlD S branched-chain amino acid
AACDMEEK_00734 7.3e-67 I alpha/beta hydrolase fold
AACDMEEK_00735 4e-25
AACDMEEK_00736 4e-57 3.6.1.27 I phosphatase
AACDMEEK_00737 4.1e-23
AACDMEEK_00738 2.1e-91 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AACDMEEK_00739 6.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
AACDMEEK_00740 3.1e-27 cspC K Cold shock protein
AACDMEEK_00741 1.6e-81 thrE S Putative threonine/serine exporter
AACDMEEK_00742 3.1e-48 S Threonine/Serine exporter, ThrE
AACDMEEK_00743 6e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AACDMEEK_00744 1.4e-86 S Sucrose-6F-phosphate phosphohydrolase
AACDMEEK_00745 1.9e-34 trxA O Belongs to the thioredoxin family
AACDMEEK_00746 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AACDMEEK_00747 3.3e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AACDMEEK_00748 4.3e-65 degV S Uncharacterised protein, DegV family COG1307
AACDMEEK_00750 4.3e-54 queT S QueT transporter
AACDMEEK_00751 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
AACDMEEK_00752 6.5e-102 IQ Enoyl-(Acyl carrier protein) reductase
AACDMEEK_00753 4.3e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AACDMEEK_00754 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AACDMEEK_00755 4.5e-88 S Alpha beta hydrolase
AACDMEEK_00756 2.4e-44 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AACDMEEK_00757 3.6e-140 V MatE
AACDMEEK_00758 1.2e-155 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
AACDMEEK_00759 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AACDMEEK_00760 1.9e-97 V ABC transporter
AACDMEEK_00761 5.7e-132 bacI V MacB-like periplasmic core domain
AACDMEEK_00762 9e-82 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AACDMEEK_00763 4.8e-26
AACDMEEK_00764 2.7e-180 yhdP S Transporter associated domain
AACDMEEK_00765 9.2e-80 ptp2 3.1.3.48 T Tyrosine phosphatase family
AACDMEEK_00766 0.0 L Helicase C-terminal domain protein
AACDMEEK_00767 4.8e-250 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AACDMEEK_00768 1.8e-211 yfnA E Amino Acid
AACDMEEK_00769 9.1e-53 zur P Belongs to the Fur family
AACDMEEK_00771 8.9e-106
AACDMEEK_00772 3.9e-08
AACDMEEK_00773 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AACDMEEK_00774 3.5e-101 glnH ET ABC transporter
AACDMEEK_00775 5.5e-86 gluC P ABC transporter permease
AACDMEEK_00776 4.9e-82 glnP P ABC transporter permease
AACDMEEK_00777 3.2e-181 steT E amino acid
AACDMEEK_00778 6.5e-21 K Acetyltransferase (GNAT) domain
AACDMEEK_00779 1.5e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
AACDMEEK_00780 7.7e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
AACDMEEK_00781 1.7e-79 K rpiR family
AACDMEEK_00782 5.6e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AACDMEEK_00783 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
AACDMEEK_00784 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AACDMEEK_00785 1e-100 rplD J Forms part of the polypeptide exit tunnel
AACDMEEK_00786 3.8e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AACDMEEK_00787 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AACDMEEK_00788 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AACDMEEK_00789 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AACDMEEK_00790 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AACDMEEK_00791 8.1e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AACDMEEK_00792 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
AACDMEEK_00793 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AACDMEEK_00794 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AACDMEEK_00795 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AACDMEEK_00796 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AACDMEEK_00797 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AACDMEEK_00798 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AACDMEEK_00799 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AACDMEEK_00800 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AACDMEEK_00801 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AACDMEEK_00802 2.1e-22 rpmD J Ribosomal protein L30
AACDMEEK_00803 1e-67 rplO J Binds to the 23S rRNA
AACDMEEK_00804 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AACDMEEK_00805 1.7e-106 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AACDMEEK_00806 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AACDMEEK_00807 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AACDMEEK_00808 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AACDMEEK_00809 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AACDMEEK_00810 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AACDMEEK_00811 4.8e-53 rplQ J Ribosomal protein L17
AACDMEEK_00812 1e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AACDMEEK_00813 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AACDMEEK_00814 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AACDMEEK_00815 9.4e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AACDMEEK_00816 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AACDMEEK_00817 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
AACDMEEK_00818 1.2e-29
AACDMEEK_00819 8.9e-246 yjbQ P TrkA C-terminal domain protein
AACDMEEK_00820 0.0 helD 3.6.4.12 L DNA helicase
AACDMEEK_00821 8e-68 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AACDMEEK_00822 1.2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
AACDMEEK_00823 7.7e-101 hrtB V ABC transporter permease
AACDMEEK_00824 2.3e-34 ygfC K Bacterial regulatory proteins, tetR family
AACDMEEK_00825 7e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AACDMEEK_00826 9.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AACDMEEK_00827 2.5e-48 M LysM domain protein
AACDMEEK_00828 1.5e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AACDMEEK_00829 8e-98 sbcC L Putative exonuclease SbcCD, C subunit
AACDMEEK_00830 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
AACDMEEK_00831 7.2e-53 perR P Belongs to the Fur family
AACDMEEK_00832 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AACDMEEK_00833 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AACDMEEK_00834 2.5e-86 S (CBS) domain
AACDMEEK_00835 3.6e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AACDMEEK_00836 1.4e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AACDMEEK_00837 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AACDMEEK_00838 3.4e-137 yabM S Polysaccharide biosynthesis protein
AACDMEEK_00839 3.6e-31 yabO J S4 domain protein
AACDMEEK_00840 1e-21 divIC D Septum formation initiator
AACDMEEK_00841 1.1e-40 yabR J RNA binding
AACDMEEK_00842 2.8e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AACDMEEK_00843 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AACDMEEK_00844 8.6e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACDMEEK_00845 2.4e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AACDMEEK_00846 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AACDMEEK_00847 2.5e-259 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AACDMEEK_00851 2.9e-146 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AACDMEEK_00852 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AACDMEEK_00853 5.1e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AACDMEEK_00854 4.6e-160 camS S sex pheromone
AACDMEEK_00855 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AACDMEEK_00856 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AACDMEEK_00857 7.3e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AACDMEEK_00858 9.8e-146 yegS 2.7.1.107 G Lipid kinase
AACDMEEK_00859 6.9e-211 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AACDMEEK_00860 2e-235 S Protein of unknown function DUF262
AACDMEEK_00861 1.7e-231 mod 2.1.1.72, 3.1.21.5 L DNA methylase
AACDMEEK_00862 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
AACDMEEK_00863 1.5e-186 K DNA binding
AACDMEEK_00864 0.0 L helicase activity
AACDMEEK_00865 1e-17 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
AACDMEEK_00866 4.9e-55 S Domain of unknown function (DUF3841)
AACDMEEK_00867 5.1e-230 yfjM S Protein of unknown function DUF262
AACDMEEK_00869 1e-167 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
AACDMEEK_00870 1.9e-158 C Oxidoreductase
AACDMEEK_00871 1.1e-71 ywlG S Belongs to the UPF0340 family
AACDMEEK_00872 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AACDMEEK_00873 1.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AACDMEEK_00874 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AACDMEEK_00875 9.7e-178 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AACDMEEK_00876 5.7e-14 ybaN S Protein of unknown function (DUF454)
AACDMEEK_00877 2.5e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AACDMEEK_00878 2.5e-200 frdC 1.3.5.4 C FAD binding domain
AACDMEEK_00879 1.1e-206 yflS P Sodium:sulfate symporter transmembrane region
AACDMEEK_00880 2e-18 yncA 2.3.1.79 S Maltose acetyltransferase
AACDMEEK_00881 8.2e-160 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AACDMEEK_00882 2.2e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
AACDMEEK_00883 2.9e-96 ypuA S Protein of unknown function (DUF1002)
AACDMEEK_00884 2e-279 3.2.1.18 GH33 M Rib/alpha-like repeat
AACDMEEK_00885 1.2e-44 K Copper transport repressor CopY TcrY
AACDMEEK_00886 6.1e-60 T Belongs to the universal stress protein A family
AACDMEEK_00887 7.6e-41 K Bacterial regulatory proteins, tetR family
AACDMEEK_00888 1.2e-57 K transcriptional
AACDMEEK_00889 8.1e-72 mleR K LysR family
AACDMEEK_00890 4.9e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
AACDMEEK_00891 3.3e-127 mleP S Sodium Bile acid symporter family
AACDMEEK_00892 4.2e-64 S ECF transporter, substrate-specific component
AACDMEEK_00893 1.8e-60 acmC 3.2.1.96 NU mannosyl-glycoprotein
AACDMEEK_00894 2.8e-73 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AACDMEEK_00895 1.8e-192 pbuX F xanthine permease
AACDMEEK_00896 3e-37 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
AACDMEEK_00897 6.9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
AACDMEEK_00898 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
AACDMEEK_00899 9.9e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AACDMEEK_00900 9.4e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
AACDMEEK_00901 5.5e-160 mgtE P Acts as a magnesium transporter
AACDMEEK_00903 1.7e-40
AACDMEEK_00904 9.7e-35 K GNAT family
AACDMEEK_00905 1.7e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
AACDMEEK_00906 2.7e-220 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
AACDMEEK_00907 9.9e-43 O ADP-ribosylglycohydrolase
AACDMEEK_00908 1.1e-218 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
AACDMEEK_00909 1.3e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AACDMEEK_00910 1.1e-156 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AACDMEEK_00911 6.2e-120 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
AACDMEEK_00912 1e-193 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
AACDMEEK_00913 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AACDMEEK_00914 4.3e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
AACDMEEK_00915 4.4e-24 S Domain of unknown function (DUF4828)
AACDMEEK_00916 5.4e-128 mocA S Oxidoreductase
AACDMEEK_00917 6.7e-160 yfmL L DEAD DEAH box helicase
AACDMEEK_00918 2e-20 S Domain of unknown function (DUF3284)
AACDMEEK_00920 4.3e-278 kup P Transport of potassium into the cell
AACDMEEK_00921 2.1e-100 malR K Transcriptional regulator, LacI family
AACDMEEK_00922 1.2e-212 malT G Major Facilitator
AACDMEEK_00923 1.7e-78 galM 5.1.3.3 G Aldose 1-epimerase
AACDMEEK_00924 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
AACDMEEK_00925 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
AACDMEEK_00926 4.8e-264 E Amino acid permease
AACDMEEK_00927 1.5e-180 pepS E Thermophilic metalloprotease (M29)
AACDMEEK_00928 3.2e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AACDMEEK_00929 1.8e-70 K Sugar-specific transcriptional regulator TrmB
AACDMEEK_00930 9.9e-123 S Sulfite exporter TauE/SafE
AACDMEEK_00931 1.2e-119 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
AACDMEEK_00932 0.0 S Bacterial membrane protein YfhO
AACDMEEK_00933 8.7e-53 gtcA S Teichoic acid glycosylation protein
AACDMEEK_00934 5.1e-54 fld C Flavodoxin
AACDMEEK_00935 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
AACDMEEK_00936 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AACDMEEK_00937 6.9e-11 mltD CBM50 M Lysin motif
AACDMEEK_00938 4.9e-93 yihY S Belongs to the UPF0761 family
AACDMEEK_00940 1.6e-197 dtpT U amino acid peptide transporter
AACDMEEK_00941 1.1e-07
AACDMEEK_00943 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AACDMEEK_00944 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
AACDMEEK_00945 2.8e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AACDMEEK_00946 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AACDMEEK_00947 2.3e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AACDMEEK_00948 1.7e-251 yhgF K Tex-like protein N-terminal domain protein
AACDMEEK_00949 4.3e-42 ydcK S Belongs to the SprT family
AACDMEEK_00951 6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AACDMEEK_00952 4.5e-129 mleP2 S Sodium Bile acid symporter family
AACDMEEK_00953 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AACDMEEK_00954 4.6e-34 S Enterocin A Immunity
AACDMEEK_00955 1.3e-222 pepC 3.4.22.40 E Peptidase C1-like family
AACDMEEK_00956 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
AACDMEEK_00957 5.3e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
AACDMEEK_00958 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AACDMEEK_00959 1.4e-153 yacL S domain protein
AACDMEEK_00960 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AACDMEEK_00961 8.1e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AACDMEEK_00962 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AACDMEEK_00963 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AACDMEEK_00964 7e-71 yacP S YacP-like NYN domain
AACDMEEK_00965 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AACDMEEK_00966 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AACDMEEK_00967 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
AACDMEEK_00968 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AACDMEEK_00969 2.1e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AACDMEEK_00970 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AACDMEEK_00971 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AACDMEEK_00972 1.6e-55
AACDMEEK_00973 1.8e-300 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AACDMEEK_00974 1.4e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AACDMEEK_00975 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AACDMEEK_00976 4.8e-45 nrdI F NrdI Flavodoxin like
AACDMEEK_00977 1.2e-27 nrdH O Glutaredoxin
AACDMEEK_00978 8.4e-76 rsmC 2.1.1.172 J Methyltransferase
AACDMEEK_00979 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AACDMEEK_00980 7.4e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AACDMEEK_00981 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AACDMEEK_00982 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AACDMEEK_00983 1.3e-28 yaaL S Protein of unknown function (DUF2508)
AACDMEEK_00984 4e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AACDMEEK_00985 3.4e-82 holB 2.7.7.7 L DNA polymerase III
AACDMEEK_00986 1.4e-40 yabA L Involved in initiation control of chromosome replication
AACDMEEK_00987 1.5e-105 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AACDMEEK_00988 1.2e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
AACDMEEK_00989 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
AACDMEEK_00990 3.1e-69 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
AACDMEEK_00991 1.2e-27 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
AACDMEEK_00992 4.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AACDMEEK_00993 3.4e-256 uup S ABC transporter, ATP-binding protein
AACDMEEK_00994 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AACDMEEK_00995 1.2e-32 S CAAX protease self-immunity
AACDMEEK_00996 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AACDMEEK_00997 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AACDMEEK_00998 1.8e-267 aha1 P COG COG0474 Cation transport ATPase
AACDMEEK_00999 6.4e-297 ydaO E amino acid
AACDMEEK_01000 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
AACDMEEK_01001 5.4e-128 comFA L Helicase C-terminal domain protein
AACDMEEK_01002 6.1e-51 comFC S Competence protein
AACDMEEK_01003 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AACDMEEK_01004 4.8e-96 yeaN P Major Facilitator Superfamily
AACDMEEK_01005 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AACDMEEK_01006 2.2e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AACDMEEK_01007 5.3e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
AACDMEEK_01008 4.6e-86 K response regulator
AACDMEEK_01009 3.5e-85 phoR 2.7.13.3 T Histidine kinase
AACDMEEK_01010 3.2e-08 KT PspC domain protein
AACDMEEK_01011 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
AACDMEEK_01012 5.6e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AACDMEEK_01013 2.1e-111 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AACDMEEK_01014 1.8e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
AACDMEEK_01015 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AACDMEEK_01016 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AACDMEEK_01017 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AACDMEEK_01018 1.3e-79 ylbE GM NAD dependent epimerase dehydratase family protein
AACDMEEK_01019 7.5e-126 rapZ S Displays ATPase and GTPase activities
AACDMEEK_01020 3.1e-152 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AACDMEEK_01021 1.8e-149 whiA K May be required for sporulation
AACDMEEK_01022 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AACDMEEK_01024 7.1e-136 cggR K Putative sugar-binding domain
AACDMEEK_01025 2.9e-174 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AACDMEEK_01026 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AACDMEEK_01027 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AACDMEEK_01028 2.1e-233 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AACDMEEK_01029 7.2e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AACDMEEK_01030 1.9e-103 K response regulator
AACDMEEK_01031 4.1e-169 T PhoQ Sensor
AACDMEEK_01032 1.2e-147 lmrP E Major Facilitator Superfamily
AACDMEEK_01033 9.2e-180 clcA P chloride
AACDMEEK_01034 2.8e-19 secG U Preprotein translocase
AACDMEEK_01035 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AACDMEEK_01036 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AACDMEEK_01037 4.1e-42 yxjI
AACDMEEK_01038 6.3e-117 ycsE S Sucrose-6F-phosphate phosphohydrolase
AACDMEEK_01039 4e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AACDMEEK_01040 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AACDMEEK_01041 1.9e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
AACDMEEK_01042 3.9e-69 dnaQ 2.7.7.7 L DNA polymerase III
AACDMEEK_01043 2.7e-115 murB 1.3.1.98 M Cell wall formation
AACDMEEK_01044 1.8e-71 S Protein of unknown function (DUF1361)
AACDMEEK_01045 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AACDMEEK_01046 5.3e-68 ybbR S YbbR-like protein
AACDMEEK_01047 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AACDMEEK_01048 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AACDMEEK_01049 1.5e-130 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
AACDMEEK_01050 1.4e-21 cutC P Participates in the control of copper homeostasis
AACDMEEK_01051 6.2e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AACDMEEK_01052 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AACDMEEK_01053 6.4e-61 ybaK J Aminoacyl-tRNA editing domain
AACDMEEK_01054 4.4e-99 rrmA 2.1.1.187 H Methyltransferase
AACDMEEK_01055 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AACDMEEK_01056 3.5e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
AACDMEEK_01057 1.2e-108 ymfF S Peptidase M16 inactive domain protein
AACDMEEK_01058 1.6e-148 ymfH S Peptidase M16
AACDMEEK_01059 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
AACDMEEK_01060 2.9e-64 ymfM S Helix-turn-helix domain
AACDMEEK_01061 4.7e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AACDMEEK_01062 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AACDMEEK_01063 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
AACDMEEK_01064 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AACDMEEK_01065 8.4e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AACDMEEK_01066 5.6e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AACDMEEK_01067 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AACDMEEK_01068 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AACDMEEK_01069 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AACDMEEK_01070 1.4e-12 yajC U Preprotein translocase
AACDMEEK_01072 4.3e-61 uspA T universal stress protein
AACDMEEK_01074 2e-208 yfnA E Amino Acid
AACDMEEK_01075 3.4e-116 lutA C Cysteine-rich domain
AACDMEEK_01076 3.1e-244 lutB C 4Fe-4S dicluster domain
AACDMEEK_01077 3.2e-66 yrjD S LUD domain
AACDMEEK_01078 2.1e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AACDMEEK_01079 7.5e-13
AACDMEEK_01080 4.2e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
AACDMEEK_01081 8.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AACDMEEK_01082 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AACDMEEK_01083 2.1e-36 yrzL S Belongs to the UPF0297 family
AACDMEEK_01084 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AACDMEEK_01085 1.9e-33 yrzB S Belongs to the UPF0473 family
AACDMEEK_01086 5.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AACDMEEK_01087 2.1e-17 cvpA S Colicin V production protein
AACDMEEK_01088 4.7e-308 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AACDMEEK_01089 7.6e-41 trxA O Belongs to the thioredoxin family
AACDMEEK_01090 4e-93 RB5993 3.1.1.3 I Pfam Lipase (class 3)
AACDMEEK_01091 1.8e-09 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AACDMEEK_01092 1.1e-14 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AACDMEEK_01093 1.4e-60 yslB S Protein of unknown function (DUF2507)
AACDMEEK_01094 1.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AACDMEEK_01095 1.5e-41 S Phosphoesterase
AACDMEEK_01098 2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AACDMEEK_01099 1.6e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AACDMEEK_01100 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AACDMEEK_01101 1.9e-200 oatA I Acyltransferase
AACDMEEK_01102 1.8e-16
AACDMEEK_01104 1.5e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AACDMEEK_01105 1.7e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
AACDMEEK_01106 2.6e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
AACDMEEK_01107 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AACDMEEK_01108 2.9e-298 S membrane
AACDMEEK_01109 4e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
AACDMEEK_01110 1.8e-27 S Protein of unknown function (DUF3290)
AACDMEEK_01111 2e-75 yviA S Protein of unknown function (DUF421)
AACDMEEK_01113 1.9e-123 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AACDMEEK_01114 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AACDMEEK_01115 8.1e-54 tag 3.2.2.20 L glycosylase
AACDMEEK_01116 3.2e-73 usp6 T universal stress protein
AACDMEEK_01118 3.4e-188 rarA L recombination factor protein RarA
AACDMEEK_01119 1e-23 yueI S Protein of unknown function (DUF1694)
AACDMEEK_01120 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AACDMEEK_01121 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
AACDMEEK_01122 1.2e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AACDMEEK_01123 3.8e-162 iscS2 2.8.1.7 E Aminotransferase class V
AACDMEEK_01124 5.5e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AACDMEEK_01125 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AACDMEEK_01126 1.1e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AACDMEEK_01127 2.4e-79 radC L DNA repair protein
AACDMEEK_01128 4.5e-21 K Cold shock
AACDMEEK_01129 1.8e-155 mreB D cell shape determining protein MreB
AACDMEEK_01130 2.1e-88 mreC M Involved in formation and maintenance of cell shape
AACDMEEK_01131 1.2e-54 mreD M rod shape-determining protein MreD
AACDMEEK_01132 1.9e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AACDMEEK_01133 1.8e-126 minD D Belongs to the ParA family
AACDMEEK_01134 1.9e-94 glnP P ABC transporter permease
AACDMEEK_01135 4e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AACDMEEK_01136 1.8e-108 aatB ET ABC transporter substrate-binding protein
AACDMEEK_01137 6.3e-99 D Alpha beta
AACDMEEK_01138 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
AACDMEEK_01140 5.2e-64 mraZ K Belongs to the MraZ family
AACDMEEK_01141 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AACDMEEK_01142 2.5e-11 ftsL D cell division protein FtsL
AACDMEEK_01143 1.4e-279 ftsI 3.4.16.4 M Penicillin-binding Protein
AACDMEEK_01144 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AACDMEEK_01145 2.6e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AACDMEEK_01146 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AACDMEEK_01147 1.6e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AACDMEEK_01148 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AACDMEEK_01149 5.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AACDMEEK_01150 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AACDMEEK_01151 3e-19 yggT S YGGT family
AACDMEEK_01152 5.9e-82 ylmH S S4 domain protein
AACDMEEK_01153 5.1e-62 divIVA D DivIVA domain protein
AACDMEEK_01154 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AACDMEEK_01155 4.2e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AACDMEEK_01156 9.7e-74 draG O ADP-ribosylglycohydrolase
AACDMEEK_01158 3.9e-86 2.7.7.12 C Domain of unknown function (DUF4931)
AACDMEEK_01159 1.1e-92 T Calcineurin-like phosphoesterase superfamily domain
AACDMEEK_01160 8.4e-48 lytE M LysM domain protein
AACDMEEK_01161 2.3e-19 glpE P Rhodanese Homology Domain
AACDMEEK_01162 2.2e-28 xlyB 3.5.1.28 CBM50 M LysM domain
AACDMEEK_01163 1.7e-158 asnA 6.3.1.1 F aspartate--ammonia ligase
AACDMEEK_01164 3.5e-194 cydA 1.10.3.14 C ubiquinol oxidase
AACDMEEK_01165 2.1e-140 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
AACDMEEK_01166 1e-203 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
AACDMEEK_01167 3e-219 cydD CO ABC transporter transmembrane region
AACDMEEK_01168 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AACDMEEK_01169 1.2e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
AACDMEEK_01170 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
AACDMEEK_01171 1.6e-145 pbuO_1 S Permease family
AACDMEEK_01172 6.8e-42 2.7.7.65 T GGDEF domain
AACDMEEK_01173 8.1e-127 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
AACDMEEK_01174 6.9e-185
AACDMEEK_01175 1.5e-206 S Protein conserved in bacteria
AACDMEEK_01176 1.5e-201 ydaM M Glycosyl transferase family group 2
AACDMEEK_01177 0.0 ydaN S Bacterial cellulose synthase subunit
AACDMEEK_01178 5.1e-119 2.7.7.65 T diguanylate cyclase activity
AACDMEEK_01179 3.2e-37 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
AACDMEEK_01180 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
AACDMEEK_01181 1e-307 L Helicase C-terminal domain protein
AACDMEEK_01182 0.0 rafA 3.2.1.22 G alpha-galactosidase
AACDMEEK_01183 1.2e-53 S Membrane
AACDMEEK_01184 2.2e-63 K helix_turn_helix, arabinose operon control protein
AACDMEEK_01185 5e-45
AACDMEEK_01186 4.5e-205 pipD E Dipeptidase
AACDMEEK_01187 2.5e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AACDMEEK_01188 2.6e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AACDMEEK_01189 4.5e-60 speG J Acetyltransferase (GNAT) domain
AACDMEEK_01190 1.8e-113 yitU 3.1.3.104 S hydrolase
AACDMEEK_01191 1.4e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
AACDMEEK_01192 7.3e-82
AACDMEEK_01193 1.5e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
AACDMEEK_01194 2.1e-43 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
AACDMEEK_01195 5.7e-83 qorB 1.6.5.2 GM NmrA-like family
AACDMEEK_01196 1.2e-39 K Transcriptional regulator
AACDMEEK_01197 2.2e-32 S CHY zinc finger
AACDMEEK_01199 3.2e-54 1.1.1.1 C Zinc-binding dehydrogenase
AACDMEEK_01201 0.0 L helicase
AACDMEEK_01203 5.7e-41 S Protein of unknown function (DUF1211)
AACDMEEK_01204 1.9e-27 ybl78 L Conserved phage C-terminus (Phg_2220_C)
AACDMEEK_01206 1.1e-39 wecD M Acetyltransferase (GNAT) family
AACDMEEK_01207 4.5e-76 cps2D 5.1.3.2 M RmlD substrate binding domain
AACDMEEK_01208 8.6e-67 H Methyltransferase domain
AACDMEEK_01210 3.7e-16 K DNA-templated transcription, initiation
AACDMEEK_01212 7.5e-09 S Protein of unknown function (DUF2922)
AACDMEEK_01215 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
AACDMEEK_01216 3.5e-28 ysxB J Cysteine protease Prp
AACDMEEK_01217 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AACDMEEK_01218 1.6e-12
AACDMEEK_01222 5.4e-71
AACDMEEK_01223 1.1e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AACDMEEK_01224 2.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AACDMEEK_01225 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
AACDMEEK_01226 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AACDMEEK_01227 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AACDMEEK_01228 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AACDMEEK_01229 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AACDMEEK_01230 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AACDMEEK_01231 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AACDMEEK_01232 3.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AACDMEEK_01233 4.1e-51 yeaL S Protein of unknown function (DUF441)
AACDMEEK_01234 2.1e-125 cvfB S S1 domain
AACDMEEK_01235 6.1e-112 xerD D recombinase XerD
AACDMEEK_01236 2.9e-294 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
AACDMEEK_01237 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AACDMEEK_01238 3.7e-188 nhaC C Na H antiporter NhaC
AACDMEEK_01239 7.8e-65 ypsA S Belongs to the UPF0398 family
AACDMEEK_01240 9.3e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
AACDMEEK_01242 2.2e-73 2.3.1.178 M GNAT acetyltransferase
AACDMEEK_01243 1.5e-67 maa 2.3.1.79 S Maltose acetyltransferase
AACDMEEK_01244 5.7e-57 3.6.1.27 I Acid phosphatase homologues
AACDMEEK_01245 5.1e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
AACDMEEK_01247 7.4e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AACDMEEK_01248 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
AACDMEEK_01249 3e-71 K Transcriptional regulator
AACDMEEK_01250 1.2e-125 akr5f 1.1.1.346 S reductase
AACDMEEK_01251 3.2e-103 EGP Major Facilitator Superfamily
AACDMEEK_01252 7.7e-80 GM NmrA-like family
AACDMEEK_01253 6.5e-33 P esterase
AACDMEEK_01254 1.9e-37 fldA C Flavodoxin
AACDMEEK_01255 3.6e-93 S Aldo/keto reductase family
AACDMEEK_01256 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AACDMEEK_01257 3.3e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AACDMEEK_01258 6.9e-214 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AACDMEEK_01259 2.1e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AACDMEEK_01260 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
AACDMEEK_01261 9.9e-61 ypbB 5.1.3.1 S Helix-turn-helix domain
AACDMEEK_01262 8.5e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
AACDMEEK_01263 7.7e-12 M Lysin motif
AACDMEEK_01264 5.8e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AACDMEEK_01265 5.8e-83 lytH 3.5.1.28 M Ami_3
AACDMEEK_01266 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
AACDMEEK_01267 2.3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AACDMEEK_01268 4.7e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AACDMEEK_01269 3.5e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AACDMEEK_01270 6.9e-91 recO L Involved in DNA repair and RecF pathway recombination
AACDMEEK_01271 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
AACDMEEK_01272 2e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AACDMEEK_01273 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
AACDMEEK_01274 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AACDMEEK_01275 5.7e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AACDMEEK_01276 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
AACDMEEK_01277 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
AACDMEEK_01278 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AACDMEEK_01279 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AACDMEEK_01281 2e-21 K Psort location Cytoplasmic, score
AACDMEEK_01282 1.8e-111 natA S Domain of unknown function (DUF4162)
AACDMEEK_01283 9.6e-84 natB CP ABC-type Na efflux pump, permease component
AACDMEEK_01284 1.8e-95 EG EamA-like transporter family
AACDMEEK_01285 2.9e-79 yjjH S Calcineurin-like phosphoesterase
AACDMEEK_01286 5.7e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AACDMEEK_01287 2.4e-40 6.3.3.2 S ASCH
AACDMEEK_01288 8.6e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
AACDMEEK_01289 1.1e-116 degV S EDD domain protein, DegV family
AACDMEEK_01290 3.1e-40 K Transcriptional regulator
AACDMEEK_01291 1.4e-202 FbpA K Fibronectin-binding protein
AACDMEEK_01292 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AACDMEEK_01293 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AACDMEEK_01294 4.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AACDMEEK_01295 1e-39 ypaA S Protein of unknown function (DUF1304)
AACDMEEK_01297 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AACDMEEK_01298 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AACDMEEK_01299 0.0 dnaE 2.7.7.7 L DNA polymerase
AACDMEEK_01300 9.5e-15 S Protein of unknown function (DUF2929)
AACDMEEK_01301 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AACDMEEK_01302 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AACDMEEK_01303 3.7e-41 XK27_04120 S Putative amino acid metabolism
AACDMEEK_01304 5.1e-159 iscS 2.8.1.7 E Aminotransferase class V
AACDMEEK_01305 5.5e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AACDMEEK_01307 7.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
AACDMEEK_01308 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AACDMEEK_01309 3.2e-160 nhaC C Na H antiporter NhaC
AACDMEEK_01310 2.7e-126 corA P CorA-like Mg2+ transporter protein
AACDMEEK_01311 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AACDMEEK_01312 4.1e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
AACDMEEK_01313 1.4e-149 S Tetratricopeptide repeat protein
AACDMEEK_01314 3.8e-136 EG EamA-like transporter family
AACDMEEK_01315 3.3e-69 alkD L DNA alkylation repair enzyme
AACDMEEK_01316 1.9e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AACDMEEK_01317 4.3e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AACDMEEK_01318 1e-77 trmK 2.1.1.217 S SAM-dependent methyltransferase
AACDMEEK_01319 1.1e-149 EGP Sugar (and other) transporter
AACDMEEK_01320 7e-15 V KxYKxGKxW signal domain protein
AACDMEEK_01322 6.1e-39
AACDMEEK_01323 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AACDMEEK_01324 1.5e-22 S Family of unknown function (DUF5322)
AACDMEEK_01325 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
AACDMEEK_01326 4.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AACDMEEK_01327 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AACDMEEK_01329 9.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AACDMEEK_01330 1.8e-172 patA 2.6.1.1 E Aminotransferase
AACDMEEK_01331 8.6e-115 glcR K DeoR C terminal sensor domain
AACDMEEK_01332 2.4e-143 ppaC 3.6.1.1 C inorganic pyrophosphatase
AACDMEEK_01333 1.3e-134 K Transcriptional regulator
AACDMEEK_01334 3.3e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AACDMEEK_01335 6.8e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AACDMEEK_01336 5.3e-193 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AACDMEEK_01337 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AACDMEEK_01338 3.5e-204 pyrP F Permease
AACDMEEK_01339 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AACDMEEK_01340 9.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AACDMEEK_01341 1.8e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AACDMEEK_01342 8.8e-57 3.1.3.18 J HAD-hyrolase-like
AACDMEEK_01343 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AACDMEEK_01344 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AACDMEEK_01345 6.3e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AACDMEEK_01346 2.6e-118 prmA J Ribosomal protein L11 methyltransferase
AACDMEEK_01347 2.9e-42 XK27_03960 S Protein of unknown function (DUF3013)
AACDMEEK_01348 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
AACDMEEK_01349 6.4e-12
AACDMEEK_01350 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AACDMEEK_01351 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
AACDMEEK_01352 4.3e-126 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AACDMEEK_01353 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AACDMEEK_01354 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AACDMEEK_01355 9.1e-43 yodB K Transcriptional regulator, HxlR family
AACDMEEK_01356 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
AACDMEEK_01357 1e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AACDMEEK_01361 5.9e-10 XK27_07105 K Helix-turn-helix XRE-family like proteins
AACDMEEK_01362 2.4e-37 K Helix-turn-helix XRE-family like proteins
AACDMEEK_01363 2.9e-35 E Zn peptidase
AACDMEEK_01365 5.6e-28 S Short C-terminal domain
AACDMEEK_01366 1.7e-17 L nuclease
AACDMEEK_01367 1.9e-13
AACDMEEK_01368 8.3e-26 polC_1 2.7.7.7 L 3' exoribonuclease, RNase T-like
AACDMEEK_01370 4.3e-14 L Belongs to the 'phage' integrase family
AACDMEEK_01371 3.4e-91 L Belongs to the 'phage' integrase family
AACDMEEK_01372 7.2e-130 lys 3.5.1.104 M Glycosyl hydrolases family 25
AACDMEEK_01373 9.5e-10 hol S Bacteriophage holin
AACDMEEK_01375 9.3e-16 G cellulose 1,4-beta-cellobiosidase activity
AACDMEEK_01379 2.2e-281 rny D peptidase
AACDMEEK_01380 1.8e-89 S Phage tail protein
AACDMEEK_01381 4.5e-101 M Phage tail tape measure protein TP901
AACDMEEK_01383 2e-24 S Phage tail tube protein
AACDMEEK_01385 3.9e-11 S Bacteriophage HK97-gp10, putative tail-component
AACDMEEK_01387 5.3e-13 L Phage gp6-like head-tail connector protein
AACDMEEK_01388 1.1e-94 S Phage capsid family
AACDMEEK_01389 2.9e-72 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
AACDMEEK_01390 5.7e-103 S Phage portal protein, HK97 family
AACDMEEK_01391 1.1e-216 S Terminase
AACDMEEK_01392 3.8e-33 L Phage terminase, small subunit
AACDMEEK_01393 1.4e-21 L HNH nucleases
AACDMEEK_01395 2.9e-16
AACDMEEK_01398 1.1e-57 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AACDMEEK_01401 9.5e-10
AACDMEEK_01408 9.3e-73 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AACDMEEK_01409 4.3e-116 L Phage integrase family
AACDMEEK_01411 2.9e-59 L Belongs to the 'phage' integrase family
AACDMEEK_01412 6.7e-25 S HNH endonuclease
AACDMEEK_01413 4.1e-08
AACDMEEK_01418 1.3e-156 S Phage plasmid primase, P4 family
AACDMEEK_01419 3.3e-178 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
AACDMEEK_01420 1.1e-35 S Protein of unknown function (DUF669)
AACDMEEK_01421 3.6e-126 L AAA domain
AACDMEEK_01422 2e-25 L VRR_NUC
AACDMEEK_01423 3.5e-17
AACDMEEK_01425 3.4e-119 L snf2 family
AACDMEEK_01430 2.8e-19 S Domain of unknown function (DUF771)
AACDMEEK_01432 3.4e-31 S ORF6C domain
AACDMEEK_01433 5.1e-14 K Helix-turn-helix XRE-family like proteins
AACDMEEK_01434 8.6e-14
AACDMEEK_01435 5.5e-58 XK27_10050 K Peptidase S24-like
AACDMEEK_01436 6e-11 M Host cell surface-exposed lipoprotein
AACDMEEK_01440 4.7e-14
AACDMEEK_01441 8.9e-116 L Belongs to the 'phage' integrase family
AACDMEEK_01443 1.3e-276 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AACDMEEK_01444 3.5e-35 S Repeat protein
AACDMEEK_01445 1.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
AACDMEEK_01446 8.7e-115 M Exporter of polyketide antibiotics
AACDMEEK_01447 3.6e-20 M Exporter of polyketide antibiotics
AACDMEEK_01448 9.8e-205 G PTS system Galactitol-specific IIC component
AACDMEEK_01449 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AACDMEEK_01450 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AACDMEEK_01451 0.0 L Domain of unknown function (DUF1998)
AACDMEEK_01453 1.4e-09
AACDMEEK_01455 8.2e-85 dprA LU DNA protecting protein DprA
AACDMEEK_01456 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AACDMEEK_01457 6.1e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AACDMEEK_01458 6.2e-24 yozE S Belongs to the UPF0346 family
AACDMEEK_01459 4.4e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
AACDMEEK_01460 2.9e-80 ypmR E GDSL-like Lipase/Acylhydrolase
AACDMEEK_01462 2.1e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AACDMEEK_01463 9.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AACDMEEK_01464 1.4e-273 yfmR S ABC transporter, ATP-binding protein
AACDMEEK_01465 3e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AACDMEEK_01466 9.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AACDMEEK_01467 3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AACDMEEK_01468 1.3e-68 xerD L Phage integrase, N-terminal SAM-like domain
AACDMEEK_01470 1.8e-56 yqeY S YqeY-like protein
AACDMEEK_01471 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AACDMEEK_01472 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AACDMEEK_01475 5.2e-101 epsJ1 M Glycosyltransferase like family 2
AACDMEEK_01476 3.7e-84 M Glycosyltransferase sugar-binding region containing DXD motif
AACDMEEK_01477 9.5e-93 M transferase activity, transferring glycosyl groups
AACDMEEK_01478 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AACDMEEK_01479 9.9e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AACDMEEK_01480 2.8e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AACDMEEK_01481 1.9e-55 dnaD L DnaD domain protein
AACDMEEK_01482 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AACDMEEK_01483 1.3e-141 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AACDMEEK_01484 1.9e-33 ypmB S Protein conserved in bacteria
AACDMEEK_01485 1.6e-227 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AACDMEEK_01486 2.3e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AACDMEEK_01487 4.1e-117 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AACDMEEK_01488 1.9e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AACDMEEK_01489 1.1e-112 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AACDMEEK_01490 2.1e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
AACDMEEK_01491 4.7e-156 comEC S Competence protein ComEC
AACDMEEK_01492 2e-69 comEB 3.5.4.12 F ComE operon protein 2
AACDMEEK_01493 5.2e-50 comEA L Competence protein ComEA
AACDMEEK_01494 1.3e-267 argS 6.1.1.19 J Arginyl-tRNA synthetase
AACDMEEK_01495 3.6e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AACDMEEK_01496 2.2e-20
AACDMEEK_01498 8.6e-122 K LysR substrate binding domain
AACDMEEK_01499 2.6e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AACDMEEK_01500 1.8e-99 S Acyltransferase family
AACDMEEK_01501 4.1e-162 purD 6.3.4.13 F Belongs to the GARS family
AACDMEEK_01502 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AACDMEEK_01503 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AACDMEEK_01504 6.9e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AACDMEEK_01505 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AACDMEEK_01506 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AACDMEEK_01507 1.5e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AACDMEEK_01508 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AACDMEEK_01509 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AACDMEEK_01510 2.4e-131 ylbL T Belongs to the peptidase S16 family
AACDMEEK_01511 6.9e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AACDMEEK_01512 1.2e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
AACDMEEK_01513 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
AACDMEEK_01514 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AACDMEEK_01515 5.1e-101 ftsW D Belongs to the SEDS family
AACDMEEK_01516 3.3e-148 manN G system, mannose fructose sorbose family IID component
AACDMEEK_01517 1.6e-114 manY G PTS system
AACDMEEK_01518 4.6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AACDMEEK_01519 0.0 typA T GTP-binding protein TypA
AACDMEEK_01520 2.4e-75 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AACDMEEK_01521 7.5e-24 yktA S Belongs to the UPF0223 family
AACDMEEK_01522 2.4e-31 1.1.1.27 C L-malate dehydrogenase activity
AACDMEEK_01523 2.4e-85 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AACDMEEK_01524 3.3e-25
AACDMEEK_01525 5e-23 ykzG S Belongs to the UPF0356 family
AACDMEEK_01526 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AACDMEEK_01527 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AACDMEEK_01528 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AACDMEEK_01529 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AACDMEEK_01530 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AACDMEEK_01531 8e-19 S Tetratricopeptide repeat
AACDMEEK_01532 3.2e-266 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AACDMEEK_01533 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AACDMEEK_01534 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AACDMEEK_01535 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
AACDMEEK_01536 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AACDMEEK_01537 8.2e-199 yfnA E amino acid
AACDMEEK_01538 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
AACDMEEK_01539 2.5e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AACDMEEK_01540 1.1e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AACDMEEK_01541 1.1e-26 ylqC S Belongs to the UPF0109 family
AACDMEEK_01542 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AACDMEEK_01543 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AACDMEEK_01544 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AACDMEEK_01545 1e-147 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AACDMEEK_01546 1.7e-213 smc D Required for chromosome condensation and partitioning
AACDMEEK_01547 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AACDMEEK_01548 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AACDMEEK_01549 7.1e-141 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AACDMEEK_01550 1.1e-244 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AACDMEEK_01551 3.3e-239 yloV S DAK2 domain fusion protein YloV
AACDMEEK_01552 5.9e-53 asp S Asp23 family, cell envelope-related function
AACDMEEK_01553 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AACDMEEK_01554 1.3e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
AACDMEEK_01555 1.1e-108 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AACDMEEK_01556 6.8e-184 KLT serine threonine protein kinase
AACDMEEK_01557 1.9e-90 stp 3.1.3.16 T phosphatase
AACDMEEK_01558 3.4e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AACDMEEK_01559 2e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AACDMEEK_01560 4.1e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AACDMEEK_01561 2.2e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AACDMEEK_01562 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AACDMEEK_01563 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AACDMEEK_01564 9.5e-94 2.7.1.89 M Phosphotransferase enzyme family
AACDMEEK_01565 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
AACDMEEK_01566 6.1e-187 rodA D Belongs to the SEDS family
AACDMEEK_01567 1.3e-13 S Protein of unknown function (DUF2969)
AACDMEEK_01568 1.7e-25 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AACDMEEK_01569 3.4e-167 mbl D Cell shape determining protein MreB Mrl
AACDMEEK_01570 1.2e-196 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AACDMEEK_01571 4.1e-15 ywzB S Protein of unknown function (DUF1146)
AACDMEEK_01572 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AACDMEEK_01573 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AACDMEEK_01574 3.9e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AACDMEEK_01575 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AACDMEEK_01576 5.4e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AACDMEEK_01577 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AACDMEEK_01578 1.3e-18 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AACDMEEK_01579 1.3e-96 atpB C it plays a direct role in the translocation of protons across the membrane
AACDMEEK_01580 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AACDMEEK_01581 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AACDMEEK_01582 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AACDMEEK_01583 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AACDMEEK_01584 6.8e-86 tdk 2.7.1.21 F thymidine kinase
AACDMEEK_01585 1.8e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
AACDMEEK_01586 3.5e-110 cobQ S glutamine amidotransferase
AACDMEEK_01587 7e-112 ampC V Beta-lactamase
AACDMEEK_01588 1.5e-31
AACDMEEK_01589 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AACDMEEK_01590 4.6e-205 glnP P ABC transporter
AACDMEEK_01592 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AACDMEEK_01593 5.6e-158 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AACDMEEK_01594 1.5e-274 dnaK O Heat shock 70 kDa protein
AACDMEEK_01595 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AACDMEEK_01596 4.1e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AACDMEEK_01597 6.7e-96 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AACDMEEK_01598 2.8e-120 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AACDMEEK_01599 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AACDMEEK_01600 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AACDMEEK_01601 9.8e-25 ylxQ J ribosomal protein
AACDMEEK_01602 1.4e-39 ylxR K Protein of unknown function (DUF448)
AACDMEEK_01603 3.7e-170 nusA K Participates in both transcription termination and antitermination
AACDMEEK_01604 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
AACDMEEK_01605 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AACDMEEK_01606 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AACDMEEK_01607 6.9e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AACDMEEK_01608 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
AACDMEEK_01609 2.9e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AACDMEEK_01610 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AACDMEEK_01611 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AACDMEEK_01612 2.7e-48 S Domain of unknown function (DUF956)
AACDMEEK_01613 3.2e-35 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AACDMEEK_01615 1.3e-246 glnA 6.3.1.2 E glutamine synthetase
AACDMEEK_01616 1.3e-45 glnR K Transcriptional regulator
AACDMEEK_01617 1.4e-205 ynbB 4.4.1.1 P aluminum resistance
AACDMEEK_01618 4.2e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AACDMEEK_01619 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
AACDMEEK_01620 2.7e-46 yqhL P Rhodanese-like protein
AACDMEEK_01621 1.5e-156 glk 2.7.1.2 G Glucokinase
AACDMEEK_01622 2.6e-25 yqgQ S Bacterial protein of unknown function (DUF910)
AACDMEEK_01623 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
AACDMEEK_01624 4.3e-39 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AACDMEEK_01625 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AACDMEEK_01626 4.6e-20 D nuclear chromosome segregation
AACDMEEK_01627 9.4e-75 yciQ P membrane protein (DUF2207)
AACDMEEK_01628 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
AACDMEEK_01629 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
AACDMEEK_01630 2.9e-26 yneF S UPF0154 protein
AACDMEEK_01631 2.2e-30 ynzC S UPF0291 protein
AACDMEEK_01632 2.5e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AACDMEEK_01633 1.6e-174 recN L May be involved in recombinational repair of damaged DNA
AACDMEEK_01634 6.6e-49 argR K Regulates arginine biosynthesis genes
AACDMEEK_01635 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AACDMEEK_01636 2.8e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AACDMEEK_01637 4.3e-17 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AACDMEEK_01638 4.4e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AACDMEEK_01639 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AACDMEEK_01640 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AACDMEEK_01641 3.7e-46 yqhY S Asp23 family, cell envelope-related function
AACDMEEK_01642 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AACDMEEK_01643 1.3e-41 dut S dUTPase
AACDMEEK_01644 5.5e-117
AACDMEEK_01645 7.3e-105
AACDMEEK_01646 1.2e-134 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
AACDMEEK_01647 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AACDMEEK_01648 1.7e-120 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AACDMEEK_01649 5.1e-167 arlS 2.7.13.3 T Histidine kinase
AACDMEEK_01650 3.1e-111 K response regulator
AACDMEEK_01652 6e-108 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AACDMEEK_01653 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AACDMEEK_01654 5.4e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AACDMEEK_01655 1.4e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AACDMEEK_01656 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AACDMEEK_01657 6.9e-37
AACDMEEK_01658 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AACDMEEK_01659 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
AACDMEEK_01660 1.5e-27 yazA L GIY-YIG catalytic domain protein
AACDMEEK_01661 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
AACDMEEK_01662 4e-89 plsC 2.3.1.51 I Acyltransferase
AACDMEEK_01663 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AACDMEEK_01664 2.7e-57 yceD S Uncharacterized ACR, COG1399
AACDMEEK_01665 1.1e-121 ylbM S Belongs to the UPF0348 family
AACDMEEK_01666 5.5e-82 H Nodulation protein S (NodS)
AACDMEEK_01667 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AACDMEEK_01668 2e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
AACDMEEK_01669 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AACDMEEK_01670 6e-30 yhbY J RNA-binding protein
AACDMEEK_01671 1.4e-14 yqeH S Ribosome biogenesis GTPase YqeH
AACDMEEK_01672 8.8e-42 L Protein of unknown function (DUF3991)
AACDMEEK_01673 7.7e-69
AACDMEEK_01675 8.8e-89 pac DM Glucan-binding protein C
AACDMEEK_01676 5.9e-21 sdrF M domain protein
AACDMEEK_01677 5e-33 L Belongs to the 'phage' integrase family
AACDMEEK_01678 2.9e-33 L Belongs to the 'phage' integrase family
AACDMEEK_01679 6.4e-07
AACDMEEK_01680 3.1e-67 D nuclear chromosome segregation
AACDMEEK_01682 1.3e-74 S Fic/DOC family
AACDMEEK_01684 4.6e-62 ruvB 3.6.4.12 L four-way junction helicase activity
AACDMEEK_01688 1.4e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
AACDMEEK_01689 5.7e-20
AACDMEEK_01697 1.6e-07
AACDMEEK_01702 2.9e-20 S Replication initiator protein A (RepA) N-terminus
AACDMEEK_01704 5.3e-09 S Arc-like DNA binding domain
AACDMEEK_01706 4.5e-10
AACDMEEK_01707 1.8e-12 K Helix-turn-helix XRE-family like proteins
AACDMEEK_01708 5.4e-88 S Fic/DOC family
AACDMEEK_01711 6.9e-37
AACDMEEK_01713 8.2e-16
AACDMEEK_01714 3.6e-112 rssA S Phospholipase, patatin family
AACDMEEK_01715 7.6e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AACDMEEK_01716 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
AACDMEEK_01717 3.3e-45 S VIT family
AACDMEEK_01718 1.2e-239 sufB O assembly protein SufB
AACDMEEK_01719 1.9e-40 nifU C SUF system FeS assembly protein, NifU family
AACDMEEK_01720 2.2e-147 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AACDMEEK_01721 7.8e-145 sufD O FeS assembly protein SufD
AACDMEEK_01722 8.1e-116 sufC O FeS assembly ATPase SufC
AACDMEEK_01723 1.3e-224 E ABC transporter, substratebinding protein
AACDMEEK_01724 2e-142 yfeO P Voltage gated chloride channel
AACDMEEK_01725 2.5e-27 K Helix-turn-helix XRE-family like proteins
AACDMEEK_01726 3.3e-136 pfoS S Phosphotransferase system, EIIC
AACDMEEK_01727 4.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
AACDMEEK_01728 2.5e-65 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
AACDMEEK_01729 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AACDMEEK_01730 1.2e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
AACDMEEK_01731 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
AACDMEEK_01732 5.8e-43 gutM K Glucitol operon activator protein (GutM)
AACDMEEK_01733 2.2e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
AACDMEEK_01734 3.1e-110 IQ NAD dependent epimerase/dehydratase family
AACDMEEK_01735 1.2e-21 M by MetaGeneAnnotator
AACDMEEK_01740 2.1e-29 S Phage minor capsid protein 2
AACDMEEK_01741 2.1e-99 fabK 1.3.1.9 S Nitronate monooxygenase
AACDMEEK_01742 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AACDMEEK_01744 1.4e-265 fbp 3.1.3.11 G phosphatase activity
AACDMEEK_01745 1.1e-70 xerD L Phage integrase, N-terminal SAM-like domain
AACDMEEK_01746 1.2e-24
AACDMEEK_01747 1.8e-12
AACDMEEK_01748 7.9e-22 S PIN domain
AACDMEEK_01749 5.3e-12 D Antitoxin component of a toxin-antitoxin (TA) module
AACDMEEK_01750 1.2e-88 mesE M Transport protein ComB
AACDMEEK_01751 5.3e-282 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AACDMEEK_01754 1.9e-56 K LytTr DNA-binding domain
AACDMEEK_01755 2e-58 2.7.13.3 T GHKL domain
AACDMEEK_01759 3.1e-16
AACDMEEK_01761 9.4e-08
AACDMEEK_01763 5.9e-39 blpT
AACDMEEK_01764 9.8e-55 S Haloacid dehalogenase-like hydrolase
AACDMEEK_01765 1.1e-19 S Haloacid dehalogenase-like hydrolase
AACDMEEK_01766 4.6e-15
AACDMEEK_01768 2.6e-159 L transposase, IS605 OrfB family
AACDMEEK_01769 9.5e-58 tlpA2 L Transposase IS200 like
AACDMEEK_01770 7.2e-188 mtnE 2.6.1.83 E Aminotransferase
AACDMEEK_01771 1e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
AACDMEEK_01772 3.4e-67 S Protein of unknown function (DUF1440)
AACDMEEK_01773 7.7e-41 S Iron-sulfur cluster assembly protein
AACDMEEK_01774 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
AACDMEEK_01775 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
AACDMEEK_01776 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AACDMEEK_01777 7.9e-155 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AACDMEEK_01778 2.7e-65 G Xylose isomerase domain protein TIM barrel
AACDMEEK_01779 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
AACDMEEK_01780 6.5e-90 nanK GK ROK family
AACDMEEK_01781 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
AACDMEEK_01782 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AACDMEEK_01783 4.3e-75 K Helix-turn-helix domain, rpiR family
AACDMEEK_01784 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
AACDMEEK_01785 6.9e-217 yjeM E Amino Acid
AACDMEEK_01787 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AACDMEEK_01788 3.1e-233 tetP J elongation factor G
AACDMEEK_01789 3.6e-277 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AACDMEEK_01790 5.1e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AACDMEEK_01791 2.8e-167 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
AACDMEEK_01792 5.6e-120 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
AACDMEEK_01793 1.4e-181 gatC G PTS system sugar-specific permease component
AACDMEEK_01794 9.2e-36 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
AACDMEEK_01795 2.7e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AACDMEEK_01796 1.7e-60 K DeoR C terminal sensor domain
AACDMEEK_01797 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AACDMEEK_01798 8e-41 L PFAM Integrase catalytic region
AACDMEEK_01799 3.9e-43 L HTH-like domain
AACDMEEK_01800 1.6e-27 L Helix-turn-helix domain
AACDMEEK_01802 9.4e-109 L Initiator Replication protein
AACDMEEK_01803 2.3e-38 S Replication initiator protein A (RepA) N-terminus
AACDMEEK_01804 5.7e-101 L Probable transposase
AACDMEEK_01805 1.2e-61 L Resolvase, N-terminal domain
AACDMEEK_01806 1.6e-16 licT K CAT RNA binding domain
AACDMEEK_01807 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
AACDMEEK_01809 9.3e-34
AACDMEEK_01810 0.0 pepN 3.4.11.2 E aminopeptidase
AACDMEEK_01811 1.8e-124 yvgN C Aldo keto reductase
AACDMEEK_01812 4.6e-55 yvbG U MarC family integral membrane protein
AACDMEEK_01813 1.9e-91 L Transposase, IS605 OrfB family
AACDMEEK_01814 1e-54 tlpA2 L Transposase IS200 like
AACDMEEK_01815 1e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
AACDMEEK_01816 2.2e-44 S Membrane
AACDMEEK_01817 5.3e-75 rhaR K helix_turn_helix, arabinose operon control protein
AACDMEEK_01818 1.7e-47 iolF EGP Major facilitator Superfamily
AACDMEEK_01819 2.3e-121 iolF EGP Major facilitator Superfamily
AACDMEEK_01820 1.2e-213 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
AACDMEEK_01821 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
AACDMEEK_01822 1.6e-217 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
AACDMEEK_01823 2.2e-108 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
AACDMEEK_01824 1.5e-191 XK27_11280 S Psort location CytoplasmicMembrane, score
AACDMEEK_01826 1.4e-103 L Belongs to the 'phage' integrase family
AACDMEEK_01827 2.6e-23 3.1.21.3 V Type I restriction modification DNA specificity domain
AACDMEEK_01828 7e-62 hsdM 2.1.1.72 V type I restriction-modification system
AACDMEEK_01830 2.5e-26 K Cro/C1-type HTH DNA-binding domain
AACDMEEK_01831 3.4e-80 S Putative inner membrane protein (DUF1819)
AACDMEEK_01832 7.7e-68 S Domain of unknown function (DUF1788)
AACDMEEK_01833 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
AACDMEEK_01834 0.0 V restriction
AACDMEEK_01835 8.2e-306 S TIGR02687 family
AACDMEEK_01836 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
AACDMEEK_01837 8.4e-50
AACDMEEK_01838 9.9e-38
AACDMEEK_01839 1.5e-08
AACDMEEK_01840 3.8e-18
AACDMEEK_01841 4.4e-24
AACDMEEK_01844 5.6e-168 potE2 E amino acid
AACDMEEK_01845 9.6e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
AACDMEEK_01846 5.2e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AACDMEEK_01847 5.6e-57 racA K Domain of unknown function (DUF1836)
AACDMEEK_01848 2.2e-82 yitS S EDD domain protein, DegV family
AACDMEEK_01849 1.8e-35 S Enterocin A Immunity
AACDMEEK_01850 4.2e-07 G Transmembrane secretion effector
AACDMEEK_01851 3e-17 G Transmembrane secretion effector
AACDMEEK_01852 8.9e-42 XK27_13030
AACDMEEK_01853 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AACDMEEK_01854 0.0 O Belongs to the peptidase S8 family
AACDMEEK_01855 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
AACDMEEK_01856 9e-102 qmcA O prohibitin homologues
AACDMEEK_01857 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
AACDMEEK_01858 9.2e-14 tnp L Transposase IS66 family
AACDMEEK_01859 5.4e-85 dps P Ferritin-like domain
AACDMEEK_01860 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
AACDMEEK_01861 4.3e-58 tlpA2 L Transposase IS200 like
AACDMEEK_01862 1.5e-159 L transposase, IS605 OrfB family
AACDMEEK_01863 1.6e-30 P Heavy-metal-associated domain
AACDMEEK_01864 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
AACDMEEK_01866 3.1e-67 L Integrase core domain
AACDMEEK_01867 2e-129 EGP Major Facilitator Superfamily
AACDMEEK_01868 1.1e-98 EGP Major Facilitator Superfamily
AACDMEEK_01869 6.3e-72 K Transcriptional regulator, LysR family
AACDMEEK_01870 1.2e-138 G Xylose isomerase-like TIM barrel
AACDMEEK_01871 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
AACDMEEK_01872 4.7e-217 1.3.5.4 C FAD binding domain
AACDMEEK_01873 8.4e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AACDMEEK_01874 2.9e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AACDMEEK_01875 1.1e-142 xerS L Phage integrase family
AACDMEEK_01879 1.8e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
AACDMEEK_01880 1.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
AACDMEEK_01881 1.3e-76 desR K helix_turn_helix, Lux Regulon
AACDMEEK_01882 2.4e-57 salK 2.7.13.3 T Histidine kinase
AACDMEEK_01883 4.2e-53 yvfS V ABC-2 type transporter
AACDMEEK_01884 8.9e-79 yvfR V ABC transporter
AACDMEEK_01886 8.2e-09 S Protein of unknown function (DUF805)
AACDMEEK_01888 2.9e-07 K Helix-turn-helix XRE-family like proteins
AACDMEEK_01890 3.5e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AACDMEEK_01891 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AACDMEEK_01892 4.8e-61 sip L Belongs to the 'phage' integrase family
AACDMEEK_01893 6.5e-07
AACDMEEK_01896 5e-30 M CHAP domain
AACDMEEK_01898 1.5e-192 U type IV secretory pathway VirB4
AACDMEEK_01899 3.5e-27
AACDMEEK_01901 3.1e-77
AACDMEEK_01902 2e-220 U TraM recognition site of TraD and TraG
AACDMEEK_01907 5.8e-149 clpB O Belongs to the ClpA ClpB family
AACDMEEK_01910 1.9e-165 topA2 5.99.1.2 G Topoisomerase IA
AACDMEEK_01911 8.8e-42 L Protein of unknown function (DUF3991)
AACDMEEK_01912 7.7e-69
AACDMEEK_01914 8.9e-89 pac DM Glucan-binding protein C
AACDMEEK_01916 5.3e-106 L Belongs to the 'phage' integrase family
AACDMEEK_01917 6.4e-07
AACDMEEK_01918 3e-67 D nuclear chromosome segregation
AACDMEEK_01920 1.3e-74 S Fic/DOC family
AACDMEEK_01922 1.5e-59 ruvB 3.6.4.12 L four-way junction helicase activity
AACDMEEK_01926 1.4e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
AACDMEEK_01927 5.7e-20
AACDMEEK_01937 2e-220 U TraM recognition site of TraD and TraG
AACDMEEK_01938 3.1e-77
AACDMEEK_01940 3.5e-27
AACDMEEK_01941 1.5e-192 U type IV secretory pathway VirB4
AACDMEEK_01943 5e-30 M CHAP domain
AACDMEEK_01946 6.5e-07
AACDMEEK_01947 4.8e-61 sip L Belongs to the 'phage' integrase family
AACDMEEK_01949 6.9e-37
AACDMEEK_01952 5.4e-88 S Fic/DOC family
AACDMEEK_01953 1.8e-12 K Helix-turn-helix XRE-family like proteins
AACDMEEK_01954 4.5e-10
AACDMEEK_01956 5.3e-09 S Arc-like DNA binding domain
AACDMEEK_01958 2.9e-20 S Replication initiator protein A (RepA) N-terminus
AACDMEEK_01963 1.6e-07
AACDMEEK_01971 5.7e-20
AACDMEEK_01972 1.4e-11 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
AACDMEEK_01974 7.2e-09 yokH G regulation of fungal-type cell wall biogenesis
AACDMEEK_01975 3.6e-91 V HNH endonuclease
AACDMEEK_01976 1.3e-25 yqfZ 3.2.1.17 M hydrolase, family 25
AACDMEEK_01977 6.3e-87 L Replication initiation factor
AACDMEEK_01980 0.0 tetP J elongation factor G
AACDMEEK_01981 4.1e-240 tetL EGP Major Facilitator Superfamily
AACDMEEK_01982 4.1e-41 L Replication initiation factor
AACDMEEK_01983 1.6e-72 catB 2.3.1.28 V This enzyme is an effector of chloramphenicol resistance in bacteria
AACDMEEK_01984 3.6e-72 pre D plasmid recombination enzyme
AACDMEEK_01985 6e-93 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
AACDMEEK_01987 8.8e-53 L Protein involved in initiation of plasmid replication
AACDMEEK_01989 6.6e-92 L Transposase, IS605 OrfB family
AACDMEEK_01990 1e-54 tlpA2 L Transposase IS200 like
AACDMEEK_01994 4e-48 L Resolvase, N terminal domain
AACDMEEK_01996 4.3e-27 HJ ligase activity
AACDMEEK_01997 1.4e-33 C Nitroreductase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)