ORF_ID e_value Gene_name EC_number CAZy COGs Description
NHGDMEJD_00001 2.6e-277 typA T GTP-binding protein TypA
NHGDMEJD_00002 2.3e-196 ftsW D Belongs to the SEDS family
NHGDMEJD_00003 5.8e-13 ftsW D Belongs to the SEDS family
NHGDMEJD_00004 1e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NHGDMEJD_00005 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NHGDMEJD_00006 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHGDMEJD_00007 7.1e-200 ylbL T Belongs to the peptidase S16 family
NHGDMEJD_00008 8.1e-82 comEA L Competence protein ComEA
NHGDMEJD_00009 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
NHGDMEJD_00010 0.0 comEC S Competence protein ComEC
NHGDMEJD_00011 2.5e-149 holA 2.7.7.7 L DNA polymerase III delta subunit
NHGDMEJD_00012 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
NHGDMEJD_00013 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHGDMEJD_00014 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHGDMEJD_00015 4.9e-165 S Tetratricopeptide repeat
NHGDMEJD_00016 2.2e-39 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHGDMEJD_00017 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NHGDMEJD_00018 9.6e-134 K LysR substrate binding domain
NHGDMEJD_00019 1.6e-52 azlD S branched-chain amino acid
NHGDMEJD_00020 6.1e-70 azlC E AzlC protein
NHGDMEJD_00021 9.4e-54 azlC E AzlC protein
NHGDMEJD_00022 2e-203 hpk31 2.7.13.3 T Histidine kinase
NHGDMEJD_00023 1.9e-62 K response regulator
NHGDMEJD_00024 4.5e-44 K response regulator
NHGDMEJD_00025 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHGDMEJD_00026 6.9e-50 deoR K sugar-binding domain protein
NHGDMEJD_00027 4.7e-109 deoR K sugar-binding domain protein
NHGDMEJD_00028 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NHGDMEJD_00029 9.6e-239 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NHGDMEJD_00030 1.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHGDMEJD_00031 4.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHGDMEJD_00032 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
NHGDMEJD_00033 3.9e-176 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHGDMEJD_00034 1.3e-13 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHGDMEJD_00035 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
NHGDMEJD_00036 5.9e-155 spo0J K Belongs to the ParB family
NHGDMEJD_00037 3.6e-140 soj D Sporulation initiation inhibitor
NHGDMEJD_00038 1e-69 noc K Belongs to the ParB family
NHGDMEJD_00039 9.2e-110
NHGDMEJD_00040 6.9e-190 EGP Sugar (and other) transporter
NHGDMEJD_00044 1.1e-240 yjcE P Sodium proton antiporter
NHGDMEJD_00045 3.6e-57
NHGDMEJD_00047 1.6e-90
NHGDMEJD_00048 1.3e-35 copA 3.6.3.54 P P-type ATPase
NHGDMEJD_00049 3.8e-291 copA 3.6.3.54 P P-type ATPase
NHGDMEJD_00050 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NHGDMEJD_00051 7.6e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NHGDMEJD_00052 2.9e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NHGDMEJD_00053 5.4e-54 EG EamA-like transporter family
NHGDMEJD_00054 0.0 XK27_08510 L Type III restriction protein res subunit
NHGDMEJD_00055 2.8e-162 XK27_08510 L Type III restriction protein res subunit
NHGDMEJD_00056 5.7e-52
NHGDMEJD_00057 1.1e-158 cylA V ABC transporter
NHGDMEJD_00058 7.4e-12 cylB V ABC-2 type transporter
NHGDMEJD_00059 3.7e-83 cylB V ABC-2 type transporter
NHGDMEJD_00060 4.2e-18 cylB V ABC-2 type transporter
NHGDMEJD_00061 1.4e-75 K LytTr DNA-binding domain
NHGDMEJD_00062 6.3e-61 S Protein of unknown function (DUF3021)
NHGDMEJD_00064 8.6e-184 L Plasmid pRiA4b ORF-3-like protein
NHGDMEJD_00066 7.6e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NHGDMEJD_00067 1.5e-92 dps P Belongs to the Dps family
NHGDMEJD_00068 2.5e-36 copZ P PFAM Heavy metal transport detoxification protein
NHGDMEJD_00069 2.9e-94 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NHGDMEJD_00070 7.2e-183 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NHGDMEJD_00071 1.8e-136 pnuC H nicotinamide mononucleotide transporter
NHGDMEJD_00072 1.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHGDMEJD_00073 4.6e-205
NHGDMEJD_00074 9.1e-53
NHGDMEJD_00075 9.1e-36
NHGDMEJD_00076 4.3e-94 yxkA S Phosphatidylethanolamine-binding protein
NHGDMEJD_00077 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
NHGDMEJD_00078 2.2e-187 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NHGDMEJD_00079 7.9e-195 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHGDMEJD_00080 1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NHGDMEJD_00082 7.7e-58
NHGDMEJD_00083 2.4e-84 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NHGDMEJD_00084 9.5e-110 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NHGDMEJD_00085 1.6e-106 EG GntP family permease
NHGDMEJD_00086 1.7e-92 EG GntP family permease
NHGDMEJD_00087 2.9e-27 KT Putative sugar diacid recognition
NHGDMEJD_00088 3e-11 KT Putative sugar diacid recognition
NHGDMEJD_00089 1.2e-132 O Bacterial dnaA protein
NHGDMEJD_00090 1.6e-238 L Integrase core domain
NHGDMEJD_00091 2.5e-269 S Putative peptidoglycan binding domain
NHGDMEJD_00094 1.3e-28 2.7.13.3 T GHKL domain
NHGDMEJD_00095 5e-75 osmC O OsmC-like protein
NHGDMEJD_00096 6.3e-154 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHGDMEJD_00097 2.5e-200 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHGDMEJD_00098 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHGDMEJD_00099 1.4e-153 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NHGDMEJD_00100 3.9e-42 3.6.1.13, 3.6.1.55 F NUDIX domain
NHGDMEJD_00101 6.4e-75 3.6.1.13, 3.6.1.55 F NUDIX domain
NHGDMEJD_00102 1.5e-211 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHGDMEJD_00103 1.5e-49 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHGDMEJD_00104 1e-104 pncA Q Isochorismatase family
NHGDMEJD_00105 1.1e-208 yegU O ADP-ribosylglycohydrolase
NHGDMEJD_00106 1.8e-256 F Belongs to the purine-cytosine permease (2.A.39) family
NHGDMEJD_00107 1.2e-70 L transposase, IS605 OrfB family
NHGDMEJD_00109 2.6e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHGDMEJD_00110 2.6e-90
NHGDMEJD_00111 1.2e-100 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHGDMEJD_00112 5.6e-52 L hmm pf00665
NHGDMEJD_00113 3.6e-45 L PFAM Integrase catalytic region
NHGDMEJD_00114 6.7e-40 S dextransucrase activity
NHGDMEJD_00115 3.5e-282 ganB 3.2.1.89 G arabinogalactan
NHGDMEJD_00116 1.4e-158 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
NHGDMEJD_00117 1.2e-64 gntR1 K Transcriptional regulator, GntR family
NHGDMEJD_00118 7.3e-83 V ABC transporter, ATP-binding protein
NHGDMEJD_00119 1.2e-42 V ABC transporter, ATP-binding protein
NHGDMEJD_00120 2.4e-90
NHGDMEJD_00121 3.6e-34 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NHGDMEJD_00122 2.9e-87 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NHGDMEJD_00123 1.7e-100 S Pfam:DUF3816
NHGDMEJD_00124 0.0 clpE O Belongs to the ClpA ClpB family
NHGDMEJD_00125 4e-47 clpE O Belongs to the ClpA ClpB family
NHGDMEJD_00126 2.2e-27
NHGDMEJD_00127 2.7e-39 ptsH G phosphocarrier protein HPR
NHGDMEJD_00128 8.8e-83 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHGDMEJD_00129 1.3e-210 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHGDMEJD_00130 1.2e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NHGDMEJD_00131 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
NHGDMEJD_00132 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHGDMEJD_00133 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
NHGDMEJD_00134 5.1e-96 P Cadmium resistance transporter
NHGDMEJD_00135 5.2e-56 K Transcriptional regulator, ArsR family
NHGDMEJD_00136 1e-240 mepA V MATE efflux family protein
NHGDMEJD_00137 1.5e-55 trxA O Belongs to the thioredoxin family
NHGDMEJD_00138 2.3e-131 terC P membrane
NHGDMEJD_00139 7.4e-177 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHGDMEJD_00140 9.7e-169 corA P CorA-like Mg2+ transporter protein
NHGDMEJD_00141 6.3e-207 helD 3.6.4.12 L DNA helicase
NHGDMEJD_00142 3.2e-228 helD 3.6.4.12 L DNA helicase
NHGDMEJD_00143 3.6e-117 dedA S SNARE associated Golgi protein
NHGDMEJD_00144 5e-127 3.1.3.73 G phosphoglycerate mutase
NHGDMEJD_00145 1.3e-235 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHGDMEJD_00146 6.6e-35 S Transglycosylase associated protein
NHGDMEJD_00148 1.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHGDMEJD_00149 3.4e-145 V domain protein
NHGDMEJD_00150 6.5e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHGDMEJD_00151 1.5e-80 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NHGDMEJD_00152 1.2e-32 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NHGDMEJD_00153 4.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NHGDMEJD_00157 2.3e-65 XK27_01125 L PFAM IS66 Orf2 family protein
NHGDMEJD_00158 2e-40 L Transposase IS66 family
NHGDMEJD_00159 2.1e-224 L Transposase IS66 family
NHGDMEJD_00161 2.3e-178 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHGDMEJD_00162 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHGDMEJD_00163 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NHGDMEJD_00164 3.2e-220 S Psort location CytoplasmicMembrane, score
NHGDMEJD_00165 3.2e-40 S Psort location CytoplasmicMembrane, score
NHGDMEJD_00166 6.6e-148 yueF S AI-2E family transporter
NHGDMEJD_00167 4.2e-94 S dextransucrase activity
NHGDMEJD_00168 8.5e-69 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NHGDMEJD_00169 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHGDMEJD_00170 5.7e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NHGDMEJD_00171 1.9e-200 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NHGDMEJD_00172 5.3e-79 KT YcbB domain
NHGDMEJD_00173 2.1e-51 KT YcbB domain
NHGDMEJD_00174 1.9e-46 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NHGDMEJD_00175 5e-48 EG EamA-like transporter family
NHGDMEJD_00176 7.7e-31 L Transposase
NHGDMEJD_00177 1.9e-245 yifK E Amino acid permease
NHGDMEJD_00178 9.9e-291 clcA P chloride
NHGDMEJD_00179 1.8e-34 secG U Preprotein translocase
NHGDMEJD_00180 2.1e-148 est 3.1.1.1 S Serine aminopeptidase, S33
NHGDMEJD_00181 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHGDMEJD_00182 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHGDMEJD_00183 6.3e-105 yxjI
NHGDMEJD_00184 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHGDMEJD_00185 1.7e-136 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NHGDMEJD_00186 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NHGDMEJD_00187 6.1e-88 K Acetyltransferase (GNAT) domain
NHGDMEJD_00188 8.9e-77 S PAS domain
NHGDMEJD_00189 9.3e-103 dnaQ 2.7.7.7 L DNA polymerase III
NHGDMEJD_00190 7.3e-169 murB 1.3.1.98 M Cell wall formation
NHGDMEJD_00191 1.2e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHGDMEJD_00192 6e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NHGDMEJD_00193 3.7e-249 fucP G Major Facilitator Superfamily
NHGDMEJD_00194 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHGDMEJD_00195 1.2e-126 ybbR S YbbR-like protein
NHGDMEJD_00196 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHGDMEJD_00197 1.6e-183 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHGDMEJD_00198 1.9e-130 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHGDMEJD_00199 8.7e-53
NHGDMEJD_00200 0.0 oatA I Acyltransferase
NHGDMEJD_00201 3.3e-77 K Transcriptional regulator
NHGDMEJD_00202 8.9e-150 XK27_02985 S Cof-like hydrolase
NHGDMEJD_00203 1.8e-78 lytE M Lysin motif
NHGDMEJD_00205 3.8e-136 K response regulator
NHGDMEJD_00206 2.9e-140 yclK 2.7.13.3 T Histidine kinase
NHGDMEJD_00207 2.6e-106 yclK 2.7.13.3 T Histidine kinase
NHGDMEJD_00208 7.3e-59 glcU U sugar transport
NHGDMEJD_00209 5.4e-87 glcU U sugar transport
NHGDMEJD_00210 1.4e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
NHGDMEJD_00211 5.3e-264 pgi 5.3.1.9 G Belongs to the GPI family
NHGDMEJD_00212 6.9e-14
NHGDMEJD_00214 5.6e-32 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NHGDMEJD_00215 3.3e-85 L PFAM transposase IS200-family protein
NHGDMEJD_00216 1.3e-276 lysP E amino acid
NHGDMEJD_00219 2.7e-120 lssY 3.6.1.27 I phosphatase
NHGDMEJD_00220 4.7e-79 S Threonine/Serine exporter, ThrE
NHGDMEJD_00221 2.1e-132 thrE S Putative threonine/serine exporter
NHGDMEJD_00222 3.5e-31 cspC K Cold shock protein
NHGDMEJD_00223 4.8e-125 sirR K iron dependent repressor
NHGDMEJD_00224 4.1e-167 czcD P cation diffusion facilitator family transporter
NHGDMEJD_00225 7.7e-118 S membrane
NHGDMEJD_00226 1.3e-109 S VIT family
NHGDMEJD_00227 5.5e-83 usp1 T Belongs to the universal stress protein A family
NHGDMEJD_00228 2e-32 L Helix-turn-helix domain
NHGDMEJD_00229 6.7e-278 pipD E Dipeptidase
NHGDMEJD_00230 0.0 yjbQ P TrkA C-terminal domain protein
NHGDMEJD_00231 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NHGDMEJD_00232 5.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHGDMEJD_00233 4e-92
NHGDMEJD_00234 1.7e-37
NHGDMEJD_00235 1.2e-105 K DNA-templated transcription, initiation
NHGDMEJD_00236 4e-28
NHGDMEJD_00237 6.3e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NHGDMEJD_00238 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NHGDMEJD_00239 5e-44 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHGDMEJD_00240 9.1e-138 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHGDMEJD_00241 2.9e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHGDMEJD_00242 9.5e-172 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHGDMEJD_00243 3.6e-44 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHGDMEJD_00244 1.4e-139 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHGDMEJD_00245 3.6e-148 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NHGDMEJD_00246 4.3e-230 mtnE 2.6.1.83 E Aminotransferase
NHGDMEJD_00247 1.9e-186 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHGDMEJD_00248 1e-47 gcvH E glycine cleavage
NHGDMEJD_00249 1.1e-220 rodA D Belongs to the SEDS family
NHGDMEJD_00250 2.7e-32 S Protein of unknown function (DUF2969)
NHGDMEJD_00251 1.4e-75 mbl D Cell shape determining protein MreB Mrl
NHGDMEJD_00252 1.4e-93 mbl D Cell shape determining protein MreB Mrl
NHGDMEJD_00253 1.2e-180 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHGDMEJD_00254 1.4e-47 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHGDMEJD_00255 1.3e-33 ywzB S Protein of unknown function (DUF1146)
NHGDMEJD_00256 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NHGDMEJD_00257 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHGDMEJD_00258 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHGDMEJD_00259 2.1e-67 ywiB S Domain of unknown function (DUF1934)
NHGDMEJD_00260 2.5e-50 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHGDMEJD_00261 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHGDMEJD_00262 3.5e-42 ybaN S Protein of unknown function (DUF454)
NHGDMEJD_00263 2e-28 S Protein of unknown function (DUF3290)
NHGDMEJD_00264 1.9e-29 S Protein of unknown function (DUF3290)
NHGDMEJD_00265 4.3e-115 yviA S Protein of unknown function (DUF421)
NHGDMEJD_00266 1.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
NHGDMEJD_00267 7.5e-21
NHGDMEJD_00268 1.2e-90 ntd 2.4.2.6 F Nucleoside
NHGDMEJD_00269 3.7e-159 3.1.3.102, 3.1.3.104 S hydrolase
NHGDMEJD_00270 1.2e-32 yrvD S Pfam:DUF1049
NHGDMEJD_00272 1.7e-47 L Belongs to the 'phage' integrase family
NHGDMEJD_00273 5e-22 S Phage derived protein Gp49-like (DUF891)
NHGDMEJD_00276 1e-25
NHGDMEJD_00277 1.1e-197 ampC V Beta-lactamase
NHGDMEJD_00278 2.1e-83 arcA 3.5.3.6 E Arginine
NHGDMEJD_00279 5.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NHGDMEJD_00280 1.8e-86 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NHGDMEJD_00281 2.5e-51 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NHGDMEJD_00282 3.3e-106 rihC 3.2.2.1 F Nucleoside
NHGDMEJD_00283 5.4e-178 M Glycosyltransferase like family 2
NHGDMEJD_00284 3e-27
NHGDMEJD_00285 5.4e-137 M repeat protein
NHGDMEJD_00286 1.4e-115 3.2.1.96, 3.5.1.28 GH73 M repeat protein
NHGDMEJD_00287 2.8e-36 3.2.1.96, 3.5.1.28 GH73 M repeat protein
NHGDMEJD_00288 7.6e-31 L PFAM transposase IS200-family protein
NHGDMEJD_00289 4e-80 arcA 3.5.3.6 E Arginine
NHGDMEJD_00290 1.2e-79 argR K Regulates arginine biosynthesis genes
NHGDMEJD_00291 6.8e-262 E Arginine ornithine antiporter
NHGDMEJD_00292 1.6e-226 arcD U Amino acid permease
NHGDMEJD_00293 1.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NHGDMEJD_00294 8.9e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NHGDMEJD_00295 6e-108 tdk 2.7.1.21 F thymidine kinase
NHGDMEJD_00296 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHGDMEJD_00297 1.4e-169 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHGDMEJD_00298 2.8e-111 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHGDMEJD_00299 5.8e-76 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHGDMEJD_00300 9.8e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHGDMEJD_00301 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHGDMEJD_00302 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHGDMEJD_00303 3.3e-195 yibE S overlaps another CDS with the same product name
NHGDMEJD_00304 6.9e-76 yibF S overlaps another CDS with the same product name
NHGDMEJD_00305 9.2e-40 yibF S overlaps another CDS with the same product name
NHGDMEJD_00306 5.9e-233 pyrP F Permease
NHGDMEJD_00307 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
NHGDMEJD_00308 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHGDMEJD_00309 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHGDMEJD_00310 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHGDMEJD_00311 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHGDMEJD_00312 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHGDMEJD_00313 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NHGDMEJD_00314 7.5e-58 ytzB S Small secreted protein
NHGDMEJD_00315 4.5e-89 glsA 3.5.1.2 E Belongs to the glutaminase family
NHGDMEJD_00316 1.6e-55 glsA 3.5.1.2 E Belongs to the glutaminase family
NHGDMEJD_00317 1.1e-186 iolS C Aldo keto reductase
NHGDMEJD_00318 9.2e-264 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NHGDMEJD_00319 3.5e-08 L DnaD domain protein
NHGDMEJD_00322 3.4e-52 galR K Transcriptional regulator
NHGDMEJD_00323 2.8e-108 tra L Transposase and inactivated derivatives, IS30 family
NHGDMEJD_00324 9.8e-82 L transposase and inactivated derivatives, IS30 family
NHGDMEJD_00325 6.3e-21 dedA 3.1.3.1 S SNARE associated Golgi protein
NHGDMEJD_00326 1.1e-207 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHGDMEJD_00327 1.5e-80 K AsnC family
NHGDMEJD_00328 1.5e-80 uspA T universal stress protein
NHGDMEJD_00329 0.0 lacS G Transporter
NHGDMEJD_00330 1.1e-40
NHGDMEJD_00331 1.2e-111 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHGDMEJD_00332 2.1e-66
NHGDMEJD_00334 4.8e-72
NHGDMEJD_00344 1.3e-07
NHGDMEJD_00347 8.9e-77
NHGDMEJD_00348 2.2e-118 S membrane
NHGDMEJD_00349 1.6e-114 GM NAD(P)H-binding
NHGDMEJD_00350 1.1e-64 yneR
NHGDMEJD_00351 3.7e-27 yfeJ 6.3.5.2 F glutamine amidotransferase
NHGDMEJD_00352 2.3e-83 yfeJ 6.3.5.2 F glutamine amidotransferase
NHGDMEJD_00353 2.3e-66 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHGDMEJD_00354 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHGDMEJD_00355 1.2e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHGDMEJD_00356 8.3e-41 yggT S YGGT family
NHGDMEJD_00357 1.3e-145 ylmH S S4 domain protein
NHGDMEJD_00358 6.4e-38 divIVA D DivIVA domain protein
NHGDMEJD_00359 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHGDMEJD_00360 9e-137 yfnA E amino acid
NHGDMEJD_00361 5.3e-53 yfnA E amino acid
NHGDMEJD_00362 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NHGDMEJD_00363 3.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHGDMEJD_00364 4.1e-40 ylqC S Belongs to the UPF0109 family
NHGDMEJD_00365 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NHGDMEJD_00366 3e-80 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHGDMEJD_00367 2.8e-120 glsA 3.5.1.2 E Belongs to the glutaminase family
NHGDMEJD_00368 2.1e-212 fhaB M Rib/alpha-like repeat
NHGDMEJD_00369 2.5e-129 narI 1.7.5.1 C Nitrate reductase
NHGDMEJD_00370 7.9e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
NHGDMEJD_00371 7.1e-291 narH 1.7.5.1 C 4Fe-4S dicluster domain
NHGDMEJD_00372 2.3e-99 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHGDMEJD_00373 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHGDMEJD_00374 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NHGDMEJD_00375 3.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NHGDMEJD_00376 3.2e-228 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NHGDMEJD_00377 7.9e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NHGDMEJD_00378 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NHGDMEJD_00379 5.1e-44
NHGDMEJD_00380 4.2e-167 comP 2.7.13.3 F Sensor histidine kinase
NHGDMEJD_00381 4.5e-17 nreC K PFAM regulatory protein LuxR
NHGDMEJD_00382 6.6e-55 clpL O associated with various cellular activities
NHGDMEJD_00383 2.7e-32
NHGDMEJD_00384 1.5e-222 patA 2.6.1.1 E Aminotransferase
NHGDMEJD_00387 6.4e-82 entB 3.5.1.19 Q Isochorismatase family
NHGDMEJD_00388 1.1e-71 hsdR 3.1.21.3 V EcoEI R protein C-terminal
NHGDMEJD_00389 1e-54 hsdR 3.1.21.3 V EcoEI R protein C-terminal
NHGDMEJD_00390 1.2e-216 hsdR 3.1.21.3 V EcoEI R protein C-terminal
NHGDMEJD_00391 6.5e-201 hsdR 3.1.21.3 V EcoEI R protein C-terminal
NHGDMEJD_00392 5.5e-101 3.1.21.3 V Type I restriction modification DNA specificity domain
NHGDMEJD_00393 7e-141 aroD S Serine hydrolase (FSH1)
NHGDMEJD_00394 6.1e-62 yagE E amino acid
NHGDMEJD_00395 7.2e-156 yagE E amino acid
NHGDMEJD_00396 6.1e-72 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NHGDMEJD_00397 3.7e-226 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NHGDMEJD_00398 5.1e-80 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NHGDMEJD_00399 8.1e-257 malT G Major Facilitator
NHGDMEJD_00400 5.4e-131 phbA 2.3.1.9 I Belongs to the thiolase family
NHGDMEJD_00401 2.9e-154 EG EamA-like transporter family
NHGDMEJD_00402 2.5e-118 L Integrase
NHGDMEJD_00403 1.7e-159 rssA S Phospholipase, patatin family
NHGDMEJD_00404 2.3e-13
NHGDMEJD_00405 6e-189 lacR K Transcriptional regulator
NHGDMEJD_00409 3.6e-55
NHGDMEJD_00410 3.4e-101 frnE Q DSBA-like thioredoxin domain
NHGDMEJD_00411 5.6e-115 I alpha/beta hydrolase fold
NHGDMEJD_00412 1.6e-169 lmrA V ABC transporter, ATP-binding protein
NHGDMEJD_00413 3.3e-40 ytgP S Polysaccharide biosynthesis protein
NHGDMEJD_00414 4.5e-42
NHGDMEJD_00415 9.3e-138 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHGDMEJD_00416 6.5e-304 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHGDMEJD_00417 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHGDMEJD_00418 2.5e-100 tag 3.2.2.20 L glycosylase
NHGDMEJD_00419 1.5e-29
NHGDMEJD_00420 1.1e-38 argS 6.1.1.19 J Arginyl-tRNA synthetase
NHGDMEJD_00421 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHGDMEJD_00422 2.6e-40 yheA S Belongs to the UPF0342 family
NHGDMEJD_00423 1.3e-229 yhaO L Ser Thr phosphatase family protein
NHGDMEJD_00424 1.5e-156 L AAA domain
NHGDMEJD_00425 2.1e-274 L AAA domain
NHGDMEJD_00426 1.2e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHGDMEJD_00428 8.3e-78 hit FG histidine triad
NHGDMEJD_00429 1.2e-137 ecsA V ABC transporter, ATP-binding protein
NHGDMEJD_00430 1.7e-221 ecsB U ABC transporter
NHGDMEJD_00431 2.8e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHGDMEJD_00432 2.2e-182 S YSIRK type signal peptide
NHGDMEJD_00433 7.3e-73 xth 3.1.11.2 L exodeoxyribonuclease III
NHGDMEJD_00434 3.2e-78 xth 3.1.11.2 L exodeoxyribonuclease III
NHGDMEJD_00435 4.4e-55 S Mazg nucleotide pyrophosphohydrolase
NHGDMEJD_00436 7.7e-35
NHGDMEJD_00437 1.1e-83
NHGDMEJD_00438 6.4e-131 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NHGDMEJD_00439 1.5e-161 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHGDMEJD_00440 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHGDMEJD_00441 2.2e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHGDMEJD_00442 3.1e-36 L Transposase
NHGDMEJD_00444 5.4e-189
NHGDMEJD_00445 5.2e-98 2.3.1.128 K acetyltransferase
NHGDMEJD_00446 5.5e-93 lytE M LysM domain protein
NHGDMEJD_00447 1.9e-183 oppD EP Psort location Cytoplasmic, score
NHGDMEJD_00449 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHGDMEJD_00450 1.4e-178 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NHGDMEJD_00451 6.4e-111 S enterobacterial common antigen metabolic process
NHGDMEJD_00452 2.4e-39 acmD M repeat protein
NHGDMEJD_00453 5.8e-96 acmD M repeat protein
NHGDMEJD_00454 9e-113 holB 2.7.7.7 L DNA polymerase III
NHGDMEJD_00455 1.6e-58 yabA L Involved in initiation control of chromosome replication
NHGDMEJD_00456 1.5e-62 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHGDMEJD_00457 1.4e-220 patA 2.6.1.1 E Aminotransferase
NHGDMEJD_00458 9.8e-43 S Uncharacterised protein family (UPF0236)
NHGDMEJD_00459 1.7e-49 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHGDMEJD_00460 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHGDMEJD_00461 7.4e-08
NHGDMEJD_00462 3.2e-17 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NHGDMEJD_00463 4.9e-251 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
NHGDMEJD_00464 1.2e-152 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NHGDMEJD_00465 6.9e-50 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
NHGDMEJD_00466 1.6e-208 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NHGDMEJD_00467 1e-110 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NHGDMEJD_00468 4.9e-99 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NHGDMEJD_00469 4.8e-137 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NHGDMEJD_00470 8.2e-196 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
NHGDMEJD_00471 5.7e-132 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NHGDMEJD_00472 6.4e-111 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
NHGDMEJD_00473 3e-262 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NHGDMEJD_00474 2.3e-147 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
NHGDMEJD_00475 6e-126 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NHGDMEJD_00476 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NHGDMEJD_00477 8.7e-53 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NHGDMEJD_00478 4.4e-118 cbiQ P Cobalt transport protein
NHGDMEJD_00479 2e-149 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
NHGDMEJD_00480 3.6e-205 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NHGDMEJD_00481 1.7e-69 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NHGDMEJD_00482 3.2e-80 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
NHGDMEJD_00483 2e-222 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NHGDMEJD_00484 2.3e-170 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NHGDMEJD_00485 2.4e-181 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
NHGDMEJD_00486 3.4e-252 hemL 5.4.3.8 H Aminotransferase class-III
NHGDMEJD_00487 1.6e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
NHGDMEJD_00488 4.8e-137 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NHGDMEJD_00489 6.4e-105 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
NHGDMEJD_00490 7.3e-132 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NHGDMEJD_00491 1.5e-175 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NHGDMEJD_00492 2.5e-62 S Domain of unknown function (DUF4430)
NHGDMEJD_00493 1.2e-81 S ECF transporter, substrate-specific component
NHGDMEJD_00494 1.6e-182 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHGDMEJD_00495 1.9e-152 oppD EP Psort location Cytoplasmic, score
NHGDMEJD_00496 1.6e-27 S Phage terminase, large subunit
NHGDMEJD_00497 0.0 S Phage portal protein, SPP1 Gp6-like
NHGDMEJD_00498 3.3e-55 S Sugar efflux transporter for intercellular exchange
NHGDMEJD_00499 9e-159 T EAL domain
NHGDMEJD_00500 6.7e-127 pgaC GT2 M Glycosyl transferase
NHGDMEJD_00501 8.1e-57 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHGDMEJD_00502 1.5e-208 cobD 4.1.1.81 E Aminotransferase class I and II
NHGDMEJD_00506 1.8e-84 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NHGDMEJD_00507 1.2e-11 L Transposase IS66 family
NHGDMEJD_00508 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
NHGDMEJD_00511 5.9e-58 L Helix-turn-helix domain
NHGDMEJD_00512 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
NHGDMEJD_00513 2.7e-134 pduB E BMC
NHGDMEJD_00514 6.2e-42 pduA_4 CQ BMC
NHGDMEJD_00515 3e-201 K helix_turn_helix, arabinose operon control protein
NHGDMEJD_00516 4.1e-150 eutJ E Hsp70 protein
NHGDMEJD_00517 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NHGDMEJD_00518 9e-167
NHGDMEJD_00519 3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NHGDMEJD_00520 2.1e-156 S AI-2E family transporter
NHGDMEJD_00521 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
NHGDMEJD_00522 1.7e-78 yybA 2.3.1.57 K Transcriptional regulator
NHGDMEJD_00523 6.1e-91 M1-874 K Domain of unknown function (DUF1836)
NHGDMEJD_00524 7.2e-92 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
NHGDMEJD_00525 4.7e-157 ypdB V (ABC) transporter
NHGDMEJD_00526 3.1e-125 yhdP S Transporter associated domain
NHGDMEJD_00527 3e-75 yhdP S Transporter associated domain
NHGDMEJD_00528 3.4e-23 nrdI F Belongs to the NrdI family
NHGDMEJD_00529 1.4e-49 nrdI F Belongs to the NrdI family
NHGDMEJD_00530 1.4e-74 S 3-demethylubiquinone-9 3-methyltransferase
NHGDMEJD_00531 2.9e-194 yeaN P Transporter, major facilitator family protein
NHGDMEJD_00532 1.3e-19 S Uncharacterised protein family (UPF0236)
NHGDMEJD_00533 5.7e-183 S Uncharacterised protein family (UPF0236)
NHGDMEJD_00552 5.1e-57 L Helix-turn-helix domain
NHGDMEJD_00553 2.1e-307 lacS G Transporter
NHGDMEJD_00554 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NHGDMEJD_00555 1.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHGDMEJD_00556 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NHGDMEJD_00557 1.3e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
NHGDMEJD_00558 7.7e-224 yxjG_1 E methionine synthase, vitamin-B12 independent
NHGDMEJD_00559 2.8e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHGDMEJD_00560 8.2e-224 mdtG EGP Major facilitator Superfamily
NHGDMEJD_00561 3.5e-151 T Calcineurin-like phosphoesterase superfamily domain
NHGDMEJD_00564 3.4e-102 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NHGDMEJD_00565 3e-143 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NHGDMEJD_00566 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
NHGDMEJD_00567 6.5e-309 trxB2 1.8.1.9 C Thioredoxin domain
NHGDMEJD_00568 3e-165 yfiC V ABC transporter
NHGDMEJD_00569 1.4e-225 pipD E Dipeptidase
NHGDMEJD_00570 2e-45 holB 2.7.7.7 L DNA polymerase III
NHGDMEJD_00571 7.6e-52 yaaQ S Cyclic-di-AMP receptor
NHGDMEJD_00572 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHGDMEJD_00573 9.7e-39 S Protein of unknown function (DUF2508)
NHGDMEJD_00574 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHGDMEJD_00575 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHGDMEJD_00576 7.3e-309 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHGDMEJD_00577 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHGDMEJD_00578 3.4e-35 nrdH O Glutaredoxin
NHGDMEJD_00579 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHGDMEJD_00580 1.2e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHGDMEJD_00581 1.8e-52 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NHGDMEJD_00582 1.8e-14
NHGDMEJD_00583 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHGDMEJD_00584 8.8e-25 ykuT M mechanosensitive ion channel
NHGDMEJD_00585 6.4e-79 ykuT M mechanosensitive ion channel
NHGDMEJD_00586 1.2e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NHGDMEJD_00587 2.7e-76 ykuL S (CBS) domain
NHGDMEJD_00588 1.6e-41 S Phosphoesterase
NHGDMEJD_00589 2.9e-44 S Phosphoesterase
NHGDMEJD_00590 1.8e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHGDMEJD_00591 1.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NHGDMEJD_00592 4.1e-98 yslB S Protein of unknown function (DUF2507)
NHGDMEJD_00593 6.1e-54 trxA O Belongs to the thioredoxin family
NHGDMEJD_00594 4.7e-194 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHGDMEJD_00595 1.2e-172 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHGDMEJD_00596 1.3e-54 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHGDMEJD_00597 1.6e-86 cvpA S Colicin V production protein
NHGDMEJD_00598 6.1e-48 yrzB S Belongs to the UPF0473 family
NHGDMEJD_00599 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHGDMEJD_00600 4.1e-43 yrzL S Belongs to the UPF0297 family
NHGDMEJD_00601 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHGDMEJD_00602 3.7e-211 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHGDMEJD_00603 1.1e-141 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NHGDMEJD_00604 1.5e-29 yajC U Preprotein translocase
NHGDMEJD_00605 2.2e-204 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHGDMEJD_00606 1.2e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHGDMEJD_00607 1.8e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHGDMEJD_00608 4.9e-40 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHGDMEJD_00609 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHGDMEJD_00610 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHGDMEJD_00611 4.2e-198 rny S Endoribonuclease that initiates mRNA decay
NHGDMEJD_00612 1.6e-12 rny S Endoribonuclease that initiates mRNA decay
NHGDMEJD_00613 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHGDMEJD_00614 3.4e-233 cinA 3.5.1.42 S Belongs to the CinA family
NHGDMEJD_00615 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHGDMEJD_00616 1.9e-141 ymfM S Helix-turn-helix domain
NHGDMEJD_00617 2.4e-250 ymfH S Peptidase M16
NHGDMEJD_00618 4.2e-231 ymfF S Peptidase M16 inactive domain protein
NHGDMEJD_00619 1.5e-138 aatB ET ABC transporter substrate-binding protein
NHGDMEJD_00620 4.7e-70 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHGDMEJD_00621 1.2e-30 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHGDMEJD_00622 3.2e-102 glnP P ABC transporter permease
NHGDMEJD_00623 8.7e-93 mreD M rod shape-determining protein MreD
NHGDMEJD_00624 5.9e-152 mreC M Involved in formation and maintenance of cell shape
NHGDMEJD_00625 2.6e-43 mreB D cell shape determining protein MreB
NHGDMEJD_00626 1.7e-162 rapZ S Displays ATPase and GTPase activities
NHGDMEJD_00627 9.1e-40 steT E amino acid
NHGDMEJD_00628 1.4e-111 steT E amino acid
NHGDMEJD_00629 3.1e-63 steT E amino acid
NHGDMEJD_00630 6.2e-131 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHGDMEJD_00631 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHGDMEJD_00632 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHGDMEJD_00633 1.5e-13
NHGDMEJD_00634 2.3e-116 yfbR S HD containing hydrolase-like enzyme
NHGDMEJD_00635 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NHGDMEJD_00636 9.1e-84 ykhA 3.1.2.20 I Thioesterase superfamily
NHGDMEJD_00637 4.2e-55 aatB ET PFAM extracellular solute-binding protein, family 3
NHGDMEJD_00638 1.3e-67 aatB ET PFAM extracellular solute-binding protein, family 3
NHGDMEJD_00639 1.3e-221 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NHGDMEJD_00640 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHGDMEJD_00641 2.9e-69 lutA C Cysteine-rich domain
NHGDMEJD_00642 1.2e-67 lutA C Cysteine-rich domain
NHGDMEJD_00643 4.4e-296 lutB C 4Fe-4S dicluster domain
NHGDMEJD_00644 2.4e-138 yrjD S LUD domain
NHGDMEJD_00645 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHGDMEJD_00646 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NHGDMEJD_00647 1.3e-159 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHGDMEJD_00648 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHGDMEJD_00649 7.5e-24 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NHGDMEJD_00650 2.4e-32 KT PspC domain protein
NHGDMEJD_00651 3.8e-154 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHGDMEJD_00652 4.9e-125 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHGDMEJD_00653 3.2e-206 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHGDMEJD_00654 7.5e-85 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHGDMEJD_00655 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHGDMEJD_00656 9e-124 comFC S Competence protein
NHGDMEJD_00657 2.3e-259 comFA L Helicase C-terminal domain protein
NHGDMEJD_00658 2e-112 yvyE 3.4.13.9 S YigZ family
NHGDMEJD_00659 1.3e-249 EGP Major facilitator Superfamily
NHGDMEJD_00660 3.3e-68 rmaI K Transcriptional regulator
NHGDMEJD_00661 9.2e-40
NHGDMEJD_00662 0.0 ydaO E amino acid
NHGDMEJD_00663 3.2e-278 ybeC E amino acid
NHGDMEJD_00664 4.2e-86 S Aminoacyl-tRNA editing domain
NHGDMEJD_00665 1.6e-169 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHGDMEJD_00666 1.3e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NHGDMEJD_00667 1.9e-89 ygfC K transcriptional regulator (TetR family)
NHGDMEJD_00668 4e-174 hrtB V ABC transporter permease
NHGDMEJD_00669 9.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NHGDMEJD_00670 0.0 yhcA V ABC transporter, ATP-binding protein
NHGDMEJD_00671 2.1e-38
NHGDMEJD_00672 2.4e-50 czrA K Transcriptional regulator, ArsR family
NHGDMEJD_00673 2.5e-11 GT2,GT4 LM gp58-like protein
NHGDMEJD_00677 8.2e-32 S GDSL-like Lipase/Acylhydrolase
NHGDMEJD_00678 2.5e-11
NHGDMEJD_00679 6.9e-178
NHGDMEJD_00682 2e-76
NHGDMEJD_00685 2.9e-81 S Bacteriophage holin family
NHGDMEJD_00686 8.8e-178 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NHGDMEJD_00687 1e-15 gntT EG Gluconate
NHGDMEJD_00688 5.3e-297 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NHGDMEJD_00689 1.7e-96 K Acetyltransferase (GNAT) domain
NHGDMEJD_00690 6.5e-41
NHGDMEJD_00691 2.4e-22
NHGDMEJD_00692 0.0 nylA 3.5.1.4 J Belongs to the amidase family
NHGDMEJD_00693 2.2e-44
NHGDMEJD_00694 2.8e-58 yhaI S Protein of unknown function (DUF805)
NHGDMEJD_00695 2.1e-301 2.1.1.72 V type I restriction-modification system
NHGDMEJD_00696 1.5e-89 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
NHGDMEJD_00697 1.8e-96 3.1.21.3 V Type I restriction modification DNA specificity domain
NHGDMEJD_00698 1.5e-180 xerC L Belongs to the 'phage' integrase family
NHGDMEJD_00699 1.4e-34 3.1.21.3 V Type I restriction modification DNA specificity domain
NHGDMEJD_00700 6e-111 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NHGDMEJD_00701 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NHGDMEJD_00702 4.3e-36 higA K addiction module antidote protein HigA
NHGDMEJD_00703 4.7e-232 L PLD-like domain
NHGDMEJD_00704 1.9e-203 L PLD-like domain
NHGDMEJD_00706 5.1e-181 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NHGDMEJD_00707 1.8e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHGDMEJD_00708 4.5e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NHGDMEJD_00709 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NHGDMEJD_00710 4.7e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHGDMEJD_00711 3.9e-104 T Ion transport 2 domain protein
NHGDMEJD_00712 0.0 S Bacterial membrane protein YfhO
NHGDMEJD_00713 5e-202 G Transporter, major facilitator family protein
NHGDMEJD_00714 2.4e-109 yvrI K sigma factor activity
NHGDMEJD_00715 1.7e-156 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NHGDMEJD_00716 8.1e-244 ywfO S HD domain protein
NHGDMEJD_00717 4.1e-150 yxeH S hydrolase
NHGDMEJD_00718 3.5e-26
NHGDMEJD_00719 5e-80 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHGDMEJD_00720 2.7e-163 K LysR substrate binding domain
NHGDMEJD_00721 5.2e-209 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NHGDMEJD_00722 1.2e-54 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHGDMEJD_00723 1.6e-183
NHGDMEJD_00724 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHGDMEJD_00725 2e-184 S Phosphotransferase system, EIIC
NHGDMEJD_00726 5.9e-21 L PFAM Integrase catalytic region
NHGDMEJD_00727 9e-77 L PFAM Integrase catalytic region
NHGDMEJD_00729 7.7e-160 metQ_4 P Belongs to the nlpA lipoprotein family
NHGDMEJD_00730 1.5e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHGDMEJD_00731 6.9e-127 O Zinc-dependent metalloprotease
NHGDMEJD_00732 1.9e-115 S Membrane
NHGDMEJD_00733 8.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NHGDMEJD_00734 1.5e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHGDMEJD_00735 9.3e-71 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHGDMEJD_00736 7.8e-236 V MatE
NHGDMEJD_00737 1.3e-266 yjeM E Amino Acid
NHGDMEJD_00738 7e-279 arlS 2.7.13.3 T Histidine kinase
NHGDMEJD_00739 1.5e-121 K response regulator
NHGDMEJD_00740 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NHGDMEJD_00741 2.9e-99 yceD S Uncharacterized ACR, COG1399
NHGDMEJD_00742 1.7e-199 ylbM S Belongs to the UPF0348 family
NHGDMEJD_00743 1.4e-141 yqeM Q Methyltransferase
NHGDMEJD_00744 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHGDMEJD_00745 1.1e-86 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NHGDMEJD_00746 6.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHGDMEJD_00747 2.6e-222 patA 2.6.1.1 E Aminotransferase
NHGDMEJD_00748 2.3e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHGDMEJD_00749 6e-85 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHGDMEJD_00750 1.3e-54 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHGDMEJD_00751 7e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHGDMEJD_00752 2.1e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHGDMEJD_00753 1e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHGDMEJD_00754 7.6e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHGDMEJD_00755 6.2e-11 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHGDMEJD_00756 2.7e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHGDMEJD_00757 1e-38 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHGDMEJD_00758 9.1e-90 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHGDMEJD_00759 1.3e-215 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHGDMEJD_00760 1e-240 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHGDMEJD_00761 3.4e-118 S Repeat protein
NHGDMEJD_00762 3.4e-123 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NHGDMEJD_00763 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHGDMEJD_00764 7.5e-58 XK27_04120 S Putative amino acid metabolism
NHGDMEJD_00765 3e-44 iscS 2.8.1.7 E Aminotransferase class V
NHGDMEJD_00766 1.1e-130 iscS 2.8.1.7 E Aminotransferase class V
NHGDMEJD_00767 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHGDMEJD_00769 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NHGDMEJD_00770 4.2e-32 cspA K Cold shock protein
NHGDMEJD_00771 1.8e-264 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHGDMEJD_00772 2.4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NHGDMEJD_00773 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHGDMEJD_00774 4e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
NHGDMEJD_00775 5.1e-116 yjbH Q Thioredoxin
NHGDMEJD_00776 1.5e-269 pipD E Dipeptidase
NHGDMEJD_00777 2.7e-111 coiA 3.6.4.12 S Competence protein
NHGDMEJD_00778 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHGDMEJD_00779 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHGDMEJD_00780 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NHGDMEJD_00781 6.7e-164 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NHGDMEJD_00782 1.1e-286 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NHGDMEJD_00783 4.8e-38 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NHGDMEJD_00784 1.4e-62 S Belongs to the UPF0246 family
NHGDMEJD_00785 2.5e-68 S Belongs to the UPF0246 family
NHGDMEJD_00786 2.5e-138 S Membrane
NHGDMEJD_00787 1.6e-75 4.4.1.5 E Glyoxalase
NHGDMEJD_00788 1e-20
NHGDMEJD_00789 1.7e-87 yueI S Protein of unknown function (DUF1694)
NHGDMEJD_00790 3.4e-244 rarA L recombination factor protein RarA
NHGDMEJD_00791 4.4e-46
NHGDMEJD_00792 4.3e-83 usp6 T universal stress protein
NHGDMEJD_00793 1.5e-208 araR K Transcriptional regulator
NHGDMEJD_00794 2.2e-159 ytbE 1.1.1.346 S Aldo keto reductase
NHGDMEJD_00795 2e-100 maa 2.3.1.79 S Maltose O-acetyltransferase
NHGDMEJD_00796 8.8e-286 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NHGDMEJD_00797 1.2e-76 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NHGDMEJD_00798 1.1e-52 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NHGDMEJD_00799 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
NHGDMEJD_00800 1.4e-22 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHGDMEJD_00801 2.4e-229 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHGDMEJD_00802 1.6e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NHGDMEJD_00803 6.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NHGDMEJD_00804 4.2e-121 S Uncharacterised protein family (UPF0236)
NHGDMEJD_00805 2.6e-21 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
NHGDMEJD_00806 3e-24
NHGDMEJD_00807 1.1e-19 relB L Addiction module antitoxin, RelB DinJ family
NHGDMEJD_00808 7.5e-91 XK27_08850 J Aminoacyl-tRNA editing domain
NHGDMEJD_00809 1e-56 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NHGDMEJD_00810 7.7e-199 V Beta-lactamase
NHGDMEJD_00811 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NHGDMEJD_00812 5.3e-91 yhiD S MgtC family
NHGDMEJD_00813 4e-121 S GyrI-like small molecule binding domain
NHGDMEJD_00815 2.1e-41 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NHGDMEJD_00816 3.4e-51 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NHGDMEJD_00817 3.2e-50 azlD E Branched-chain amino acid transport
NHGDMEJD_00818 1.1e-116 azlC E azaleucine resistance protein AzlC
NHGDMEJD_00819 2.6e-266 K Aminotransferase class I and II
NHGDMEJD_00820 1.9e-305 S amidohydrolase
NHGDMEJD_00821 1.6e-165 S reductase
NHGDMEJD_00822 1.6e-93 2.3.1.183 M Acetyltransferase GNAT family
NHGDMEJD_00823 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NHGDMEJD_00824 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
NHGDMEJD_00825 4.8e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHGDMEJD_00826 0.0 asnB 6.3.5.4 E Asparagine synthase
NHGDMEJD_00827 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHGDMEJD_00828 1.7e-11 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHGDMEJD_00829 7.1e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHGDMEJD_00830 1.9e-107 jag S R3H domain protein
NHGDMEJD_00831 3.5e-13 jag S R3H domain protein
NHGDMEJD_00832 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHGDMEJD_00833 1.2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHGDMEJD_00834 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NHGDMEJD_00835 5.1e-45 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHGDMEJD_00836 1e-156 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHGDMEJD_00837 2e-32 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHGDMEJD_00838 4.2e-127 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHGDMEJD_00839 1.7e-34 yaaA S S4 domain protein YaaA
NHGDMEJD_00840 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHGDMEJD_00841 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHGDMEJD_00842 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHGDMEJD_00843 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NHGDMEJD_00844 2.5e-71 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHGDMEJD_00845 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHGDMEJD_00846 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NHGDMEJD_00847 5.9e-17 rplI J Binds to the 23S rRNA
NHGDMEJD_00848 1.1e-37 rplI J Binds to the 23S rRNA
NHGDMEJD_00849 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NHGDMEJD_00850 2.3e-117 yttB EGP Major facilitator Superfamily
NHGDMEJD_00851 1.7e-79 yttB EGP Major facilitator Superfamily
NHGDMEJD_00852 1.5e-60
NHGDMEJD_00853 2.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NHGDMEJD_00854 3.1e-101 K DNA-binding helix-turn-helix protein
NHGDMEJD_00856 4.3e-22 K helix_turn_helix multiple antibiotic resistance protein
NHGDMEJD_00857 1.6e-32 K helix_turn_helix multiple antibiotic resistance protein
NHGDMEJD_00858 1.9e-23
NHGDMEJD_00859 2.8e-185
NHGDMEJD_00860 8.4e-31
NHGDMEJD_00861 1.5e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NHGDMEJD_00862 2.2e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHGDMEJD_00863 7.5e-103 fic D Fic/DOC family
NHGDMEJD_00864 5.1e-69
NHGDMEJD_00865 4e-62 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NHGDMEJD_00866 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NHGDMEJD_00867 6.6e-93 L nuclease
NHGDMEJD_00868 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NHGDMEJD_00869 3e-212 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHGDMEJD_00870 7.2e-20 M Glycosyl hydrolases family 25
NHGDMEJD_00871 1.7e-145 ywqE 3.1.3.48 GM PHP domain protein
NHGDMEJD_00872 6.6e-159 snf 2.7.11.1 KL domain protein
NHGDMEJD_00873 0.0 snf 2.7.11.1 KL domain protein
NHGDMEJD_00875 1.5e-42 S Protein of unknown function (DUF3800)
NHGDMEJD_00876 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHGDMEJD_00877 1.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHGDMEJD_00878 1.1e-65 purR 2.4.2.7 F pur operon repressor
NHGDMEJD_00879 3.1e-69 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NHGDMEJD_00880 3.2e-128 znuB U ABC 3 transport family
NHGDMEJD_00881 7.7e-123 fhuC P ABC transporter
NHGDMEJD_00882 1.3e-170 znuA P Belongs to the bacterial solute-binding protein 9 family
NHGDMEJD_00883 1.8e-59 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHGDMEJD_00884 2.1e-77 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHGDMEJD_00885 8e-128 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHGDMEJD_00886 1.1e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHGDMEJD_00887 4.6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHGDMEJD_00888 7.9e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHGDMEJD_00889 1.6e-117 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NHGDMEJD_00890 2.9e-237 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NHGDMEJD_00891 1.1e-173 K AI-2E family transporter
NHGDMEJD_00892 3.6e-24 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NHGDMEJD_00893 7.3e-269 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NHGDMEJD_00894 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NHGDMEJD_00895 3.5e-134 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NHGDMEJD_00896 2.8e-38 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHGDMEJD_00897 2.4e-27 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHGDMEJD_00898 4.5e-60 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHGDMEJD_00899 1.5e-123 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHGDMEJD_00900 1.1e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHGDMEJD_00901 6.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NHGDMEJD_00902 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHGDMEJD_00903 4.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHGDMEJD_00904 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHGDMEJD_00905 2.8e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHGDMEJD_00906 6.6e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NHGDMEJD_00907 1.6e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHGDMEJD_00908 2.2e-298 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NHGDMEJD_00909 1.2e-246 purD 6.3.4.13 F Belongs to the GARS family
NHGDMEJD_00910 9.7e-103 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHGDMEJD_00911 3.2e-176
NHGDMEJD_00912 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHGDMEJD_00913 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHGDMEJD_00914 1.6e-105 ypsA S Belongs to the UPF0398 family
NHGDMEJD_00915 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHGDMEJD_00916 7.7e-85 F Belongs to the NrdI family
NHGDMEJD_00917 1.2e-232 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NHGDMEJD_00918 6.9e-71 rnhA 3.1.26.4 L Ribonuclease HI
NHGDMEJD_00919 1.5e-65 esbA S Family of unknown function (DUF5322)
NHGDMEJD_00920 1.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHGDMEJD_00921 4.8e-176 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHGDMEJD_00922 1.9e-206 carA 6.3.5.5 F Belongs to the CarA family
NHGDMEJD_00923 1.7e-243 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NHGDMEJD_00924 1.3e-215 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NHGDMEJD_00925 0.0 FbpA K Fibronectin-binding protein
NHGDMEJD_00926 1.7e-162 degV S EDD domain protein, DegV family
NHGDMEJD_00927 3e-29
NHGDMEJD_00928 6e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHGDMEJD_00929 3.1e-161 gspA M family 8
NHGDMEJD_00930 1.2e-160 S Alpha beta hydrolase
NHGDMEJD_00931 4.8e-96 K Acetyltransferase (GNAT) domain
NHGDMEJD_00932 7.9e-39 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NHGDMEJD_00933 7.9e-125 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHGDMEJD_00934 1.9e-47 yhbY J RNA-binding protein
NHGDMEJD_00935 4.9e-201 yqeH S Ribosome biogenesis GTPase YqeH
NHGDMEJD_00936 2.8e-96 yqeG S HAD phosphatase, family IIIA
NHGDMEJD_00937 4.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHGDMEJD_00938 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NHGDMEJD_00939 6.3e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHGDMEJD_00940 8.1e-134 dnaI L Primosomal protein DnaI
NHGDMEJD_00941 8.3e-25 dnaI L Primosomal protein DnaI
NHGDMEJD_00942 3.2e-208 dnaB L replication initiation and membrane attachment
NHGDMEJD_00943 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHGDMEJD_00944 9.3e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHGDMEJD_00945 7.4e-73 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHGDMEJD_00946 2.4e-72 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHGDMEJD_00947 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHGDMEJD_00948 1.8e-119 yoaK S Protein of unknown function (DUF1275)
NHGDMEJD_00949 1.4e-119 ybhL S Belongs to the BI1 family
NHGDMEJD_00950 2.1e-133 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NHGDMEJD_00951 1.6e-94 K Transcriptional regulator (TetR family)
NHGDMEJD_00952 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
NHGDMEJD_00953 2e-152
NHGDMEJD_00954 3.1e-17 3.2.1.14 GH18
NHGDMEJD_00955 1.5e-82 zur P Belongs to the Fur family
NHGDMEJD_00956 5.2e-104 gmk2 2.7.4.8 F Guanylate kinase
NHGDMEJD_00957 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NHGDMEJD_00958 2.1e-85 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NHGDMEJD_00959 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NHGDMEJD_00960 1.6e-260 G Major Facilitator Superfamily
NHGDMEJD_00961 4.2e-49 V DNA modification
NHGDMEJD_00963 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NHGDMEJD_00965 1.7e-226 S cog cog1373
NHGDMEJD_00966 3.3e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NHGDMEJD_00967 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHGDMEJD_00968 7e-161 EG EamA-like transporter family
NHGDMEJD_00969 5e-27 Q pyridine nucleotide-disulphide oxidoreductase
NHGDMEJD_00970 1.6e-118 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHGDMEJD_00971 5e-19 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHGDMEJD_00972 1.4e-95 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHGDMEJD_00973 3e-37 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHGDMEJD_00974 2e-157 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHGDMEJD_00975 2.9e-69 pipD E Dipeptidase
NHGDMEJD_00976 9.2e-36 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHGDMEJD_00977 4.3e-43 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHGDMEJD_00978 4.3e-135 gntR K UbiC transcription regulator-associated domain protein
NHGDMEJD_00979 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
NHGDMEJD_00980 8.9e-86 F NUDIX domain
NHGDMEJD_00981 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHGDMEJD_00982 4.1e-148 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHGDMEJD_00983 2.3e-212 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHGDMEJD_00984 4.1e-100 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHGDMEJD_00985 1.2e-171 lacX 5.1.3.3 G Aldose 1-epimerase
NHGDMEJD_00986 2.9e-243 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHGDMEJD_00987 1e-140 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHGDMEJD_00988 6.4e-41 dprA LU DNA protecting protein DprA
NHGDMEJD_00989 1.5e-110 dprA LU DNA protecting protein DprA
NHGDMEJD_00990 1.2e-143 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHGDMEJD_00991 6.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHGDMEJD_00992 1.2e-35 yozE S Belongs to the UPF0346 family
NHGDMEJD_00993 7.4e-109 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NHGDMEJD_00994 9e-21 ypmR E lipolytic protein G-D-S-L family
NHGDMEJD_00995 1.7e-137 ypmR E lipolytic protein G-D-S-L family
NHGDMEJD_00996 8.1e-154 DegV S EDD domain protein, DegV family
NHGDMEJD_00997 1.2e-78 hlyIII S protein, hemolysin III
NHGDMEJD_00998 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHGDMEJD_00999 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHGDMEJD_01000 1.3e-191 yfmR S ABC transporter, ATP-binding protein
NHGDMEJD_01001 1.4e-133 yfmR S ABC transporter, ATP-binding protein
NHGDMEJD_01002 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHGDMEJD_01003 3.9e-237 S Tetratricopeptide repeat protein
NHGDMEJD_01004 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHGDMEJD_01005 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NHGDMEJD_01006 5.6e-35 rpsA 1.17.7.4 J Ribosomal protein S1
NHGDMEJD_01007 9.9e-139 rpsA 1.17.7.4 J Ribosomal protein S1
NHGDMEJD_01008 6.9e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NHGDMEJD_01010 1.4e-48 S membrane
NHGDMEJD_01011 1.8e-104 K Transcriptional regulator C-terminal region
NHGDMEJD_01012 2.4e-164 akr5f 1.1.1.346 S reductase
NHGDMEJD_01013 1.2e-10 K Transcriptional regulator
NHGDMEJD_01014 2.1e-137 K Transcriptional regulator
NHGDMEJD_01015 2e-166 ansA 3.5.1.1 EJ L-asparaginase, type I
NHGDMEJD_01016 1e-155 ypuA S Protein of unknown function (DUF1002)
NHGDMEJD_01017 1.7e-221 aadAT EK Aminotransferase, class I
NHGDMEJD_01018 1.7e-128 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NHGDMEJD_01019 1.6e-35 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NHGDMEJD_01020 9.2e-155 tesE Q hydratase
NHGDMEJD_01021 2.8e-108 S Alpha beta hydrolase
NHGDMEJD_01023 2.6e-89 lacA S transferase hexapeptide repeat
NHGDMEJD_01024 2.1e-160 K Transcriptional regulator
NHGDMEJD_01025 1.2e-88 C Flavodoxin
NHGDMEJD_01026 8.6e-56 yphJ 4.1.1.44 S decarboxylase
NHGDMEJD_01027 5.5e-102 M Protein of unknown function (DUF3737)
NHGDMEJD_01028 2.3e-228 4.4.1.8 E Aminotransferase, class I
NHGDMEJD_01029 4.7e-163 mleP3 S Membrane transport protein
NHGDMEJD_01030 4.4e-126 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
NHGDMEJD_01032 2.3e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NHGDMEJD_01033 8.5e-50 HA62_12640 S GCN5-related N-acetyl-transferase
NHGDMEJD_01034 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHGDMEJD_01035 1e-66 pepC 3.4.22.40 E Peptidase C1-like family
NHGDMEJD_01036 4.2e-175 pepC 3.4.22.40 E Peptidase C1-like family
NHGDMEJD_01037 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NHGDMEJD_01038 2.6e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHGDMEJD_01039 1.1e-119 tcyB E ABC transporter
NHGDMEJD_01040 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NHGDMEJD_01041 6.3e-170 I alpha/beta hydrolase fold
NHGDMEJD_01042 2.2e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHGDMEJD_01043 4.3e-262 S Bacterial membrane protein, YfhO
NHGDMEJD_01044 1.1e-43 S Bacterial membrane protein, YfhO
NHGDMEJD_01045 7e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NHGDMEJD_01046 2.4e-178 L Belongs to the 'phage' integrase family
NHGDMEJD_01047 7.4e-194 3.1.21.3 V Type I restriction modification DNA specificity domain
NHGDMEJD_01048 8.7e-268 hsdM 2.1.1.72 V type I restriction-modification system
NHGDMEJD_01049 1.9e-121
NHGDMEJD_01050 6.1e-268 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHGDMEJD_01052 3.5e-188 yegS 2.7.1.107 G Lipid kinase
NHGDMEJD_01053 2.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHGDMEJD_01054 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHGDMEJD_01055 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHGDMEJD_01056 3.3e-203 camS S sex pheromone
NHGDMEJD_01057 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHGDMEJD_01058 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NHGDMEJD_01059 9.4e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NHGDMEJD_01060 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHGDMEJD_01061 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
NHGDMEJD_01062 5.5e-141 IQ reductase
NHGDMEJD_01063 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NHGDMEJD_01064 9.1e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHGDMEJD_01065 1.2e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHGDMEJD_01066 1.2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHGDMEJD_01067 1.5e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHGDMEJD_01068 1.9e-147 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHGDMEJD_01069 1.1e-62 rplQ J Ribosomal protein L17
NHGDMEJD_01070 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHGDMEJD_01071 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHGDMEJD_01072 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHGDMEJD_01073 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NHGDMEJD_01074 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHGDMEJD_01075 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHGDMEJD_01076 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHGDMEJD_01077 6.8e-64 rplO J Binds to the 23S rRNA
NHGDMEJD_01078 2.9e-24 rpmD J Ribosomal protein L30
NHGDMEJD_01079 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHGDMEJD_01080 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHGDMEJD_01081 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHGDMEJD_01082 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHGDMEJD_01083 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHGDMEJD_01084 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHGDMEJD_01085 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHGDMEJD_01086 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHGDMEJD_01087 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHGDMEJD_01088 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
NHGDMEJD_01089 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHGDMEJD_01090 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHGDMEJD_01091 9.5e-33 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHGDMEJD_01092 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHGDMEJD_01093 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHGDMEJD_01094 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHGDMEJD_01095 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NHGDMEJD_01096 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHGDMEJD_01097 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NHGDMEJD_01098 5.4e-200 L Transposase
NHGDMEJD_01099 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHGDMEJD_01100 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHGDMEJD_01101 5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHGDMEJD_01102 2.7e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NHGDMEJD_01103 1.5e-201 ykiI
NHGDMEJD_01104 5.7e-77 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHGDMEJD_01105 2.9e-212 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NHGDMEJD_01106 1.1e-38 yfeO P Voltage gated chloride channel
NHGDMEJD_01107 1e-159 yfeO P Voltage gated chloride channel
NHGDMEJD_01108 2.4e-226 sptS 2.7.13.3 T Histidine kinase
NHGDMEJD_01109 1.9e-118 K response regulator
NHGDMEJD_01110 8.2e-87 2.7.6.5 T Region found in RelA / SpoT proteins
NHGDMEJD_01111 1.8e-16
NHGDMEJD_01112 2.9e-31
NHGDMEJD_01113 1.9e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NHGDMEJD_01114 1.8e-161 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NHGDMEJD_01115 3.3e-209 bacI V MacB-like periplasmic core domain
NHGDMEJD_01116 1.1e-13 V ABC transporter
NHGDMEJD_01117 1.1e-81 V ABC transporter
NHGDMEJD_01118 1.4e-145 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHGDMEJD_01119 2.1e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NHGDMEJD_01120 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHGDMEJD_01121 6.5e-150 E Glyoxalase-like domain
NHGDMEJD_01122 7.5e-155 glcU U sugar transport
NHGDMEJD_01123 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NHGDMEJD_01124 2.9e-96 S reductase
NHGDMEJD_01126 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHGDMEJD_01127 8.2e-182 ABC-SBP S ABC transporter
NHGDMEJD_01128 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NHGDMEJD_01129 6.4e-219 htrA 3.4.21.107 O serine protease
NHGDMEJD_01130 1.2e-154 vicX 3.1.26.11 S domain protein
NHGDMEJD_01131 2.6e-152 yycI S YycH protein
NHGDMEJD_01132 4.9e-251 yycH S YycH protein
NHGDMEJD_01133 0.0 vicK 2.7.13.3 T Histidine kinase
NHGDMEJD_01134 3.1e-130 K response regulator
NHGDMEJD_01136 3.6e-174 lmrA 3.6.3.44 V ABC transporter
NHGDMEJD_01137 3.8e-139 4.1.1.22 H Histidine carboxylase PI chain
NHGDMEJD_01138 1.4e-29 4.1.1.22 H Histidine carboxylase PI chain
NHGDMEJD_01139 2.5e-97 S Family of unknown function (DUF5449)
NHGDMEJD_01140 7.1e-250 hisS 6.1.1.21 J histidyl-tRNA synthetase
NHGDMEJD_01141 2e-60 nhaC C Na H antiporter NhaC
NHGDMEJD_01142 1.5e-130 nhaC C Na H antiporter NhaC
NHGDMEJD_01143 7e-173 pbuX F xanthine permease
NHGDMEJD_01144 6.2e-140 pipD E Dipeptidase
NHGDMEJD_01145 5.3e-43 pipD E Dipeptidase
NHGDMEJD_01146 4.2e-29 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NHGDMEJD_01147 1.6e-143 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NHGDMEJD_01148 1.6e-233 mntH P H( )-stimulated, divalent metal cation uptake system
NHGDMEJD_01149 2.1e-12 Q Methyltransferase
NHGDMEJD_01150 2.9e-59 Q Methyltransferase
NHGDMEJD_01151 1.4e-116 ktrA P domain protein
NHGDMEJD_01152 8.1e-241 ktrB P Potassium uptake protein
NHGDMEJD_01153 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NHGDMEJD_01154 3.5e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NHGDMEJD_01155 6.9e-225 G Glycosyl hydrolases family 8
NHGDMEJD_01156 4.8e-246 ydaM M Glycosyl transferase
NHGDMEJD_01157 1e-137
NHGDMEJD_01158 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
NHGDMEJD_01159 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHGDMEJD_01160 2.6e-155 pstA P Phosphate transport system permease protein PstA
NHGDMEJD_01161 1.1e-153 pstC P probably responsible for the translocation of the substrate across the membrane
NHGDMEJD_01162 7.8e-104 pstS P Phosphate
NHGDMEJD_01163 1e-130 K Transcriptional regulatory protein, C-terminal domain protein
NHGDMEJD_01164 1.8e-45 L Transposase
NHGDMEJD_01165 0.0 cadA P P-type ATPase
NHGDMEJD_01166 3.1e-228 5.4.2.7 G Metalloenzyme superfamily
NHGDMEJD_01168 3.8e-159 1.6.5.2 GM NAD(P)H-binding
NHGDMEJD_01169 5.8e-52 K Transcriptional regulator
NHGDMEJD_01170 5e-151 proX M ABC transporter, substrate-binding protein, QAT family
NHGDMEJD_01171 1.1e-66 proWZ P ABC transporter permease
NHGDMEJD_01172 1.3e-142 proV E ABC transporter, ATP-binding protein
NHGDMEJD_01173 5.8e-104 proW P ABC transporter, permease protein
NHGDMEJD_01174 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NHGDMEJD_01175 3.1e-159 clcA P chloride
NHGDMEJD_01176 7.8e-85 clcA P chloride
NHGDMEJD_01177 4.4e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NHGDMEJD_01178 2.9e-51 metI P ABC transporter permease
NHGDMEJD_01179 6.7e-41 metI P ABC transporter permease
NHGDMEJD_01180 1.5e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHGDMEJD_01181 3.9e-156 metQ1 P Belongs to the nlpA lipoprotein family
NHGDMEJD_01182 4.9e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NHGDMEJD_01183 1.7e-221 norA EGP Major facilitator Superfamily
NHGDMEJD_01184 8.6e-44 1.3.5.4 S FMN binding
NHGDMEJD_01185 4.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHGDMEJD_01186 2.8e-85 yfnA E amino acid
NHGDMEJD_01187 3.9e-165 yfnA E amino acid
NHGDMEJD_01188 6.3e-257 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHGDMEJD_01190 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHGDMEJD_01191 0.0 helD 3.6.4.12 L DNA helicase
NHGDMEJD_01192 3.5e-10 ndk 2.7.4.6 F Belongs to the NDK family
NHGDMEJD_01193 8.5e-59 ndk 2.7.4.6 F Belongs to the NDK family
NHGDMEJD_01194 1.3e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NHGDMEJD_01195 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHGDMEJD_01196 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NHGDMEJD_01197 2.8e-202 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NHGDMEJD_01198 2.7e-18 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NHGDMEJD_01199 1.1e-178
NHGDMEJD_01200 4.2e-132 cobB K SIR2 family
NHGDMEJD_01202 3.1e-107 yunF F Protein of unknown function DUF72
NHGDMEJD_01203 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHGDMEJD_01204 1.4e-47 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHGDMEJD_01205 1.5e-157 tatD L hydrolase, TatD family
NHGDMEJD_01206 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHGDMEJD_01207 3.8e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHGDMEJD_01208 6.8e-37 veg S Biofilm formation stimulator VEG
NHGDMEJD_01209 2e-48 L PFAM transposase IS200-family protein
NHGDMEJD_01210 4.7e-126 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHGDMEJD_01211 2.8e-266 glnPH2 P ABC transporter permease
NHGDMEJD_01212 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NHGDMEJD_01213 2.9e-70 yqeY S YqeY-like protein
NHGDMEJD_01214 1.2e-140 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NHGDMEJD_01215 3e-167 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHGDMEJD_01216 3e-53 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHGDMEJD_01217 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
NHGDMEJD_01218 3.1e-32 bioY S BioY family
NHGDMEJD_01219 1.5e-47 bioY S BioY family
NHGDMEJD_01220 2.4e-181 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHGDMEJD_01221 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
NHGDMEJD_01222 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHGDMEJD_01223 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NHGDMEJD_01224 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHGDMEJD_01225 1.4e-94 recO L Involved in DNA repair and RecF pathway recombination
NHGDMEJD_01226 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NHGDMEJD_01227 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NHGDMEJD_01228 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHGDMEJD_01229 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
NHGDMEJD_01230 5.5e-36
NHGDMEJD_01231 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHGDMEJD_01233 2.7e-92 yxiO S Vacuole effluxer Atg22 like
NHGDMEJD_01234 4.9e-111 yxiO S Vacuole effluxer Atg22 like
NHGDMEJD_01235 1.4e-219 npp S type I phosphodiesterase nucleotide pyrophosphatase
NHGDMEJD_01236 3.7e-225 E amino acid
NHGDMEJD_01237 3.2e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHGDMEJD_01239 3.5e-28 WQ51_00220 K Helix-turn-helix XRE-family like proteins
NHGDMEJD_01240 4.2e-15 S Protein of unknown function (DUF3278)
NHGDMEJD_01241 1.6e-94 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHGDMEJD_01242 5.6e-269 frdC 1.3.5.4 C FAD binding domain
NHGDMEJD_01243 1.2e-253 yflS P Sodium:sulfate symporter transmembrane region
NHGDMEJD_01244 1.7e-132 mleR K LysR family
NHGDMEJD_01245 9.4e-253 yjjP S Putative threonine/serine exporter
NHGDMEJD_01246 4.5e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
NHGDMEJD_01247 1.9e-281 emrY EGP Major facilitator Superfamily
NHGDMEJD_01248 5.3e-133 I Alpha beta
NHGDMEJD_01249 9.6e-45 I Alpha beta
NHGDMEJD_01250 1.6e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NHGDMEJD_01251 4.3e-205 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHGDMEJD_01252 2.2e-168 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NHGDMEJD_01254 0.0 L Helicase C-terminal domain protein
NHGDMEJD_01255 1.1e-107 L Helicase C-terminal domain protein
NHGDMEJD_01256 1.5e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
NHGDMEJD_01257 2.1e-182 S Aldo keto reductase
NHGDMEJD_01259 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHGDMEJD_01260 2e-62 psiE S Phosphate-starvation-inducible E
NHGDMEJD_01261 5.5e-103 ydeN S Serine hydrolase
NHGDMEJD_01263 1.9e-50 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHGDMEJD_01264 1.8e-78 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHGDMEJD_01265 2.3e-257 nhaC C Na H antiporter NhaC
NHGDMEJD_01266 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
NHGDMEJD_01267 5.7e-115 ywnB S NAD(P)H-binding
NHGDMEJD_01268 4.4e-38
NHGDMEJD_01269 2.6e-132 IQ Dehydrogenase reductase
NHGDMEJD_01270 3.3e-242 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NHGDMEJD_01271 5.6e-39 hxlR K regulation of RNA biosynthetic process
NHGDMEJD_01272 7.9e-168 G Belongs to the carbohydrate kinase PfkB family
NHGDMEJD_01273 5e-113 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHGDMEJD_01274 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHGDMEJD_01275 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHGDMEJD_01276 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
NHGDMEJD_01277 5.1e-81 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHGDMEJD_01278 2.8e-27 stp 3.1.3.16 T phosphatase
NHGDMEJD_01279 6e-94 stp 3.1.3.16 T phosphatase
NHGDMEJD_01280 0.0 KLT serine threonine protein kinase
NHGDMEJD_01281 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHGDMEJD_01282 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NHGDMEJD_01283 7.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
NHGDMEJD_01284 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NHGDMEJD_01285 4.7e-58 asp S Asp23 family, cell envelope-related function
NHGDMEJD_01286 0.0 yloV S DAK2 domain fusion protein YloV
NHGDMEJD_01287 1.9e-47 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHGDMEJD_01288 2.2e-162 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHGDMEJD_01289 1.4e-150 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHGDMEJD_01290 2e-152 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHGDMEJD_01291 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHGDMEJD_01292 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHGDMEJD_01293 0.0 smc D Required for chromosome condensation and partitioning
NHGDMEJD_01294 2e-150 smc D Required for chromosome condensation and partitioning
NHGDMEJD_01295 1.4e-65 S enterobacterial common antigen metabolic process
NHGDMEJD_01296 2.6e-120 M transferase activity, transferring glycosyl groups
NHGDMEJD_01297 6.5e-58 M transferase activity, transferring glycosyl groups
NHGDMEJD_01298 3.2e-155 waaB GT4 M Glycosyl transferases group 1
NHGDMEJD_01299 2.5e-65 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NHGDMEJD_01300 5.1e-165 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NHGDMEJD_01301 1.4e-105 M biosynthesis protein
NHGDMEJD_01302 4.3e-217 cps3F
NHGDMEJD_01303 1.6e-185 glf 5.4.99.9 M UDP-galactopyranose mutase
NHGDMEJD_01304 1.7e-122 rfbP 2.7.8.6 M Bacterial sugar transferase
NHGDMEJD_01305 5.3e-291 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NHGDMEJD_01306 4.5e-62 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NHGDMEJD_01308 8.6e-86 ydcK S Belongs to the SprT family
NHGDMEJD_01309 0.0 yhgF K Tex-like protein N-terminal domain protein
NHGDMEJD_01310 3.9e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHGDMEJD_01311 1.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHGDMEJD_01312 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
NHGDMEJD_01313 2.5e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NHGDMEJD_01314 2.9e-304 aspT P Predicted Permease Membrane Region
NHGDMEJD_01315 9.7e-253 EGP Major facilitator Superfamily
NHGDMEJD_01316 1.5e-115
NHGDMEJD_01319 5.2e-161 yjjH S Calcineurin-like phosphoesterase
NHGDMEJD_01320 1.4e-154 dtpT U amino acid peptide transporter
NHGDMEJD_01321 1.5e-84 dtpT U amino acid peptide transporter
NHGDMEJD_01322 2.8e-19
NHGDMEJD_01324 1.3e-81 tlpA2 L Transposase IS200 like
NHGDMEJD_01325 7.2e-245 brnQ U Component of the transport system for branched-chain amino acids
NHGDMEJD_01326 2.1e-168 GK ROK family
NHGDMEJD_01327 5e-259 tetP J elongation factor G
NHGDMEJD_01328 4.3e-112 tetP J elongation factor G
NHGDMEJD_01329 5.1e-81 uspA T universal stress protein
NHGDMEJD_01330 2.1e-90 lplA 6.3.1.20 H Lipoate-protein ligase
NHGDMEJD_01331 2.8e-81 lplA 6.3.1.20 H Lipoate-protein ligase
NHGDMEJD_01332 1.9e-63
NHGDMEJD_01333 5.2e-14
NHGDMEJD_01334 4.5e-121
NHGDMEJD_01335 1.5e-137 V ABC transporter
NHGDMEJD_01336 8.2e-213 EGP Major facilitator Superfamily
NHGDMEJD_01337 3.5e-258 G PTS system Galactitol-specific IIC component
NHGDMEJD_01338 8.8e-184 1.6.5.5 C Zinc-binding dehydrogenase
NHGDMEJD_01339 2.6e-163
NHGDMEJD_01340 1e-72 K Transcriptional regulator
NHGDMEJD_01341 5.8e-168 D Alpha beta
NHGDMEJD_01342 2.2e-52 ypaA S Protein of unknown function (DUF1304)
NHGDMEJD_01343 0.0 yjcE P Sodium proton antiporter
NHGDMEJD_01344 8.6e-48 yvlA
NHGDMEJD_01345 3.6e-41 P Cobalt transport protein
NHGDMEJD_01346 2.5e-54 P Cobalt transport protein
NHGDMEJD_01347 1.1e-62 cbiO1 S ABC transporter, ATP-binding protein
NHGDMEJD_01348 8.5e-151 cbiO1 S ABC transporter, ATP-binding protein
NHGDMEJD_01349 1.9e-98 S ABC-type cobalt transport system, permease component
NHGDMEJD_01350 6.6e-134 S membrane transporter protein
NHGDMEJD_01351 2.5e-138 IQ KR domain
NHGDMEJD_01352 1.5e-272 argS 6.1.1.19 J Arginyl-tRNA synthetase
NHGDMEJD_01353 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NHGDMEJD_01354 8.4e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHGDMEJD_01356 3.3e-40
NHGDMEJD_01357 1e-43
NHGDMEJD_01358 4.2e-217 folP 2.5.1.15 H dihydropteroate synthase
NHGDMEJD_01359 1.1e-86 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NHGDMEJD_01360 1.1e-12 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NHGDMEJD_01361 2.7e-42 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHGDMEJD_01362 6.5e-171 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHGDMEJD_01363 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NHGDMEJD_01364 1.2e-94 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NHGDMEJD_01365 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHGDMEJD_01366 8.7e-74
NHGDMEJD_01368 1.9e-43
NHGDMEJD_01369 9.5e-14 S CAAX protease self-immunity
NHGDMEJD_01370 1.3e-96 S CAAX protease self-immunity
NHGDMEJD_01371 2.1e-32
NHGDMEJD_01372 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHGDMEJD_01373 4.6e-188 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NHGDMEJD_01374 5.9e-114
NHGDMEJD_01375 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
NHGDMEJD_01376 3.2e-189 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHGDMEJD_01377 1.9e-86 uspA T Belongs to the universal stress protein A family
NHGDMEJD_01378 5.8e-202 pepV 3.5.1.18 E dipeptidase PepV
NHGDMEJD_01379 4.9e-51 pepV 3.5.1.18 E dipeptidase PepV
NHGDMEJD_01380 4.5e-117 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHGDMEJD_01381 1.2e-100 ytgP S Polysaccharide biosynthesis protein
NHGDMEJD_01382 4e-71 yneR S Belongs to the HesB IscA family
NHGDMEJD_01383 0.0 S membrane
NHGDMEJD_01384 1.3e-31 S membrane
NHGDMEJD_01385 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NHGDMEJD_01386 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHGDMEJD_01387 1.4e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHGDMEJD_01388 3.2e-23 gluP 3.4.21.105 S Peptidase, S54 family
NHGDMEJD_01389 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NHGDMEJD_01390 1.5e-183 glk 2.7.1.2 G Glucokinase
NHGDMEJD_01391 9.1e-68 yqhL P Rhodanese-like protein
NHGDMEJD_01392 5.9e-22 S Protein of unknown function (DUF3042)
NHGDMEJD_01393 2.5e-33 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHGDMEJD_01394 5.9e-137 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHGDMEJD_01395 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
NHGDMEJD_01396 3.7e-84 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHGDMEJD_01397 3.4e-202 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHGDMEJD_01398 1.1e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NHGDMEJD_01399 3.9e-12
NHGDMEJD_01400 1.3e-156 P Belongs to the nlpA lipoprotein family
NHGDMEJD_01401 3.8e-84 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHGDMEJD_01402 1.3e-51 S Iron-sulfur cluster assembly protein
NHGDMEJD_01403 2.7e-152
NHGDMEJD_01404 6.4e-165
NHGDMEJD_01405 1.8e-12
NHGDMEJD_01406 6.5e-90 dut S Protein conserved in bacteria
NHGDMEJD_01409 2.6e-112 K Transcriptional regulator
NHGDMEJD_01410 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NHGDMEJD_01411 7.4e-55 ysxB J Cysteine protease Prp
NHGDMEJD_01412 1.3e-37 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NHGDMEJD_01413 8.6e-133 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHGDMEJD_01414 1.7e-204 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NHGDMEJD_01415 4.5e-123 J 2'-5' RNA ligase superfamily
NHGDMEJD_01416 2.2e-70 yqhY S Asp23 family, cell envelope-related function
NHGDMEJD_01417 3.6e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHGDMEJD_01418 3.4e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHGDMEJD_01419 6.7e-203 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHGDMEJD_01420 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHGDMEJD_01421 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHGDMEJD_01422 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NHGDMEJD_01423 1e-78 argR K Regulates arginine biosynthesis genes
NHGDMEJD_01424 6.3e-174 recN L May be involved in recombinational repair of damaged DNA
NHGDMEJD_01426 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NHGDMEJD_01427 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHGDMEJD_01428 9.9e-97 S NADPH-dependent FMN reductase
NHGDMEJD_01429 1.1e-122 MA20_14895 S Conserved hypothetical protein 698
NHGDMEJD_01430 4.5e-137 I alpha/beta hydrolase fold
NHGDMEJD_01431 3.2e-164 lsa S ABC transporter
NHGDMEJD_01432 9.2e-71 lsa S ABC transporter
NHGDMEJD_01433 1.9e-89 S Protein of unknown function (DUF1440)
NHGDMEJD_01434 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHGDMEJD_01435 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NHGDMEJD_01436 1.8e-71 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NHGDMEJD_01437 5.6e-62 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NHGDMEJD_01438 2.1e-174 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NHGDMEJD_01439 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NHGDMEJD_01440 1.8e-87 ypmB S Protein conserved in bacteria
NHGDMEJD_01441 5.1e-125 dnaD L DnaD domain protein
NHGDMEJD_01442 1.4e-162 EG EamA-like transporter family
NHGDMEJD_01443 1.2e-09 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NHGDMEJD_01444 4.1e-116 S Domain of unknown function (DUF4811)
NHGDMEJD_01445 9.5e-220 lmrB EGP Major facilitator Superfamily
NHGDMEJD_01446 1.7e-31 lmrB EGP Major facilitator Superfamily
NHGDMEJD_01447 2.6e-74 merR K MerR HTH family regulatory protein
NHGDMEJD_01448 2.9e-57
NHGDMEJD_01449 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHGDMEJD_01450 8.3e-221 S CAAX protease self-immunity
NHGDMEJD_01451 3.6e-109 glnP P ABC transporter permease
NHGDMEJD_01452 2.4e-110 gluC P ABC transporter permease
NHGDMEJD_01453 1.5e-152 glnH ET ABC transporter
NHGDMEJD_01454 3.2e-33 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHGDMEJD_01455 3.6e-80 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHGDMEJD_01456 6.4e-42 clpL O associated with various cellular activities
NHGDMEJD_01458 2.3e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
NHGDMEJD_01459 2.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHGDMEJD_01460 2.8e-73 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NHGDMEJD_01461 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NHGDMEJD_01462 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NHGDMEJD_01463 3.6e-140 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NHGDMEJD_01464 1.5e-42 malR K Transcriptional regulator, LacI family
NHGDMEJD_01465 8.5e-119 malR K Transcriptional regulator, LacI family
NHGDMEJD_01466 5e-46 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHGDMEJD_01467 5e-50 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHGDMEJD_01468 6.9e-108 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHGDMEJD_01469 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHGDMEJD_01470 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NHGDMEJD_01471 4.3e-269 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHGDMEJD_01472 9.8e-67 yabR J RNA binding
NHGDMEJD_01473 2.3e-57 divIC D Septum formation initiator
NHGDMEJD_01474 1.6e-39 yabO J S4 domain protein
NHGDMEJD_01475 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHGDMEJD_01476 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHGDMEJD_01477 3.6e-114 S (CBS) domain
NHGDMEJD_01478 3.1e-147 tesE Q hydratase
NHGDMEJD_01479 2.1e-243 codA 3.5.4.1 F cytosine deaminase
NHGDMEJD_01480 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
NHGDMEJD_01481 4.5e-183 ccpA K catabolite control protein A
NHGDMEJD_01482 1.8e-137
NHGDMEJD_01483 3.5e-132 yebC K Transcriptional regulatory protein
NHGDMEJD_01484 2.3e-111 comGA NU Type II IV secretion system protein
NHGDMEJD_01485 4.9e-54 comGA NU Type II IV secretion system protein
NHGDMEJD_01486 2.6e-169 comGB NU type II secretion system
NHGDMEJD_01487 7.1e-47 comGC U competence protein ComGC
NHGDMEJD_01488 1.5e-79 NU general secretion pathway protein
NHGDMEJD_01489 4.8e-45
NHGDMEJD_01490 3.6e-73
NHGDMEJD_01492 2.5e-89 ytxK 2.1.1.72 L N-6 DNA Methylase
NHGDMEJD_01493 5.5e-43 ytxK 2.1.1.72 L N-6 DNA Methylase
NHGDMEJD_01494 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHGDMEJD_01495 8.8e-118 S Calcineurin-like phosphoesterase
NHGDMEJD_01496 4.4e-100 yutD S Protein of unknown function (DUF1027)
NHGDMEJD_01497 2.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHGDMEJD_01498 2.3e-82 S Protein of unknown function (DUF1461)
NHGDMEJD_01499 2.8e-88 dedA S SNARE-like domain protein
NHGDMEJD_01500 1e-151 htpX O Belongs to the peptidase M48B family
NHGDMEJD_01501 7e-93 lemA S LemA family
NHGDMEJD_01502 5.2e-22 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHGDMEJD_01503 4.8e-53 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHGDMEJD_01504 9.8e-28 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NHGDMEJD_01505 9.9e-40 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NHGDMEJD_01506 3.5e-143 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NHGDMEJD_01507 2.2e-11 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NHGDMEJD_01508 1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHGDMEJD_01509 5.1e-125 srtA 3.4.22.70 M sortase family
NHGDMEJD_01510 2.7e-168 S Alpha/beta hydrolase of unknown function (DUF915)
NHGDMEJD_01511 6.1e-241 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHGDMEJD_01512 4.6e-41 rpmE2 J Ribosomal protein L31
NHGDMEJD_01513 8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHGDMEJD_01514 2.8e-154 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NHGDMEJD_01515 6.4e-111 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NHGDMEJD_01516 8e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
NHGDMEJD_01517 5.3e-104 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHGDMEJD_01518 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHGDMEJD_01519 1.2e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHGDMEJD_01520 1.9e-141 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHGDMEJD_01521 1.3e-46 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHGDMEJD_01522 5.7e-166 xerD D recombinase XerD
NHGDMEJD_01523 1.6e-168 cvfB S S1 domain
NHGDMEJD_01524 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NHGDMEJD_01525 0.0 dnaE 2.7.7.7 L DNA polymerase
NHGDMEJD_01526 2.8e-38 S Protein of unknown function (DUF2929)
NHGDMEJD_01527 6.4e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHGDMEJD_01528 2.8e-159 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHGDMEJD_01529 2e-112 trmK 2.1.1.217 S SAM-dependent methyltransferase
NHGDMEJD_01530 7.4e-26 S PFAM Archaeal ATPase
NHGDMEJD_01531 4.7e-76 S PFAM Archaeal ATPase
NHGDMEJD_01532 7.8e-10 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHGDMEJD_01533 6e-119 amtB P ammonium transporter
NHGDMEJD_01534 2.2e-73 amtB P ammonium transporter
NHGDMEJD_01535 3e-256 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NHGDMEJD_01536 1e-84 yvbK 3.1.3.25 K GNAT family
NHGDMEJD_01537 2.5e-92
NHGDMEJD_01538 1.4e-124 pnb C nitroreductase
NHGDMEJD_01539 2.2e-84 ogt 2.1.1.63 L Methyltransferase
NHGDMEJD_01540 1.1e-235 pbuG S permease
NHGDMEJD_01541 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHGDMEJD_01542 1.5e-12 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHGDMEJD_01543 2.2e-226 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHGDMEJD_01544 7e-217 iscS2 2.8.1.7 E Aminotransferase class V
NHGDMEJD_01545 4.8e-151 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHGDMEJD_01546 7e-68 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHGDMEJD_01547 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHGDMEJD_01548 1.9e-167 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHGDMEJD_01549 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
NHGDMEJD_01550 3.3e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NHGDMEJD_01551 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NHGDMEJD_01552 1.7e-79 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NHGDMEJD_01553 8.9e-195 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NHGDMEJD_01554 3.1e-26 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NHGDMEJD_01555 4.8e-232 ndh 1.6.99.3 C NADH dehydrogenase
NHGDMEJD_01556 9.4e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHGDMEJD_01557 1.2e-122 radC L DNA repair protein
NHGDMEJD_01558 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
NHGDMEJD_01559 8.6e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NHGDMEJD_01560 4.3e-89 ABC-SBP S ABC transporter
NHGDMEJD_01561 5.2e-41 ABC-SBP S ABC transporter
NHGDMEJD_01562 1e-78 M PFAM NLP P60 protein
NHGDMEJD_01564 7.8e-14 relB L RelB antitoxin
NHGDMEJD_01565 1e-108 S Protein of unknown function (DUF3278)
NHGDMEJD_01567 2.9e-11
NHGDMEJD_01568 6.4e-252 S ABC transporter, ATP-binding protein
NHGDMEJD_01569 1.8e-147 S Putative ABC-transporter type IV
NHGDMEJD_01570 1.5e-106 NU mannosyl-glycoprotein
NHGDMEJD_01571 9.9e-250 brnQ U Component of the transport system for branched-chain amino acids
NHGDMEJD_01572 1.3e-232 S Uncharacterized protein conserved in bacteria (DUF2325)
NHGDMEJD_01573 9.1e-155 nrnB S DHHA1 domain
NHGDMEJD_01574 1.5e-33 nrnB S DHHA1 domain
NHGDMEJD_01575 1.1e-49
NHGDMEJD_01576 9e-127 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHGDMEJD_01577 1.1e-11 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHGDMEJD_01578 3.3e-18 S Domain of unknown function (DUF4767)
NHGDMEJD_01579 1.6e-54
NHGDMEJD_01580 6e-123 yrkL S Flavodoxin-like fold
NHGDMEJD_01582 1.4e-65 yeaO S Protein of unknown function, DUF488
NHGDMEJD_01583 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NHGDMEJD_01584 1.4e-209 3.1.3.1 S associated with various cellular activities
NHGDMEJD_01585 5.6e-247 S Putative metallopeptidase domain
NHGDMEJD_01586 3.6e-48
NHGDMEJD_01587 1.6e-96 pepO 3.4.24.71 O Peptidase family M13
NHGDMEJD_01588 6.8e-267 pepO 3.4.24.71 O Peptidase family M13
NHGDMEJD_01589 3.9e-113 K Helix-turn-helix XRE-family like proteins
NHGDMEJD_01590 1.5e-91 ymdB S Macro domain protein
NHGDMEJD_01591 2.7e-36 EGP Major facilitator Superfamily
NHGDMEJD_01592 9.8e-150 EGP Major facilitator Superfamily
NHGDMEJD_01593 2.2e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHGDMEJD_01594 1.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHGDMEJD_01595 7.4e-160 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NHGDMEJD_01596 0.0 ysaB V FtsX-like permease family
NHGDMEJD_01597 6.8e-136 macB2 V ABC transporter, ATP-binding protein
NHGDMEJD_01598 8.7e-184 T Histidine kinase-like ATPases
NHGDMEJD_01599 1.5e-132 K response regulator
NHGDMEJD_01600 9.9e-160 ytbE 1.1.1.346 S Aldo keto reductase
NHGDMEJD_01601 8e-219 XK27_08635 S UPF0210 protein
NHGDMEJD_01602 2.1e-39 gcvR T Belongs to the UPF0237 family
NHGDMEJD_01603 6.2e-176 1.1.1.346 C Aldo keto reductase
NHGDMEJD_01604 2.9e-162 K LysR substrate binding domain protein
NHGDMEJD_01605 2.8e-87 C Flavodoxin
NHGDMEJD_01606 1.7e-62 yphH S Cupin domain
NHGDMEJD_01607 4.5e-74 yeaL S UPF0756 membrane protein
NHGDMEJD_01608 2.3e-246 EGP Major facilitator Superfamily
NHGDMEJD_01609 5e-75 copY K Copper transport repressor CopY TcrY
NHGDMEJD_01610 2.2e-246 yhdP S Transporter associated domain
NHGDMEJD_01611 0.0 ubiB S ABC1 family
NHGDMEJD_01612 7.6e-149 S DUF218 domain
NHGDMEJD_01613 5.3e-53 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHGDMEJD_01614 7e-23 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHGDMEJD_01615 4.1e-27 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHGDMEJD_01616 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHGDMEJD_01617 0.0 uvrA3 L excinuclease ABC, A subunit
NHGDMEJD_01618 1e-122 S SNARE associated Golgi protein
NHGDMEJD_01619 9.8e-197 N Uncharacterized conserved protein (DUF2075)
NHGDMEJD_01620 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHGDMEJD_01622 3.5e-255 yifK E Amino acid permease
NHGDMEJD_01623 7.7e-160 endA V DNA/RNA non-specific endonuclease
NHGDMEJD_01624 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHGDMEJD_01625 2.2e-117 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHGDMEJD_01626 1.7e-201 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NHGDMEJD_01627 1.9e-36 pipD E Dipeptidase
NHGDMEJD_01628 6.7e-220 pipD E Dipeptidase
NHGDMEJD_01629 9.2e-24 3.4.21.88 K Peptidase S24-like
NHGDMEJD_01630 1.4e-10 3.4.21.88 K Peptidase S24-like
NHGDMEJD_01631 1e-81
NHGDMEJD_01632 4.7e-76
NHGDMEJD_01633 6.4e-13
NHGDMEJD_01634 8.1e-142
NHGDMEJD_01635 5.4e-225 3.6.4.12 L Belongs to the 'phage' integrase family
NHGDMEJD_01636 1.1e-59 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHGDMEJD_01637 9.3e-267 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHGDMEJD_01638 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHGDMEJD_01639 0.0 dnaK O Heat shock 70 kDa protein
NHGDMEJD_01640 1.2e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHGDMEJD_01641 1.5e-39 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHGDMEJD_01642 5.7e-103 iunH2 3.2.2.1 F nucleoside hydrolase
NHGDMEJD_01643 1.5e-66 iunH2 3.2.2.1 F nucleoside hydrolase
NHGDMEJD_01644 4.7e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NHGDMEJD_01645 1e-127 L hmm pf00665
NHGDMEJD_01646 5.1e-87 L Helix-turn-helix domain
NHGDMEJD_01647 2e-25 L Helix-turn-helix domain
NHGDMEJD_01648 5.7e-30 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NHGDMEJD_01649 2.5e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NHGDMEJD_01650 3e-254 yagE E amino acid
NHGDMEJD_01651 2.6e-85 dps P Belongs to the Dps family
NHGDMEJD_01652 1.1e-234 pacL 3.6.3.8 P P-type ATPase
NHGDMEJD_01653 9.6e-226 pacL 3.6.3.8 P P-type ATPase
NHGDMEJD_01654 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NHGDMEJD_01655 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHGDMEJD_01656 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHGDMEJD_01657 4.7e-135 potB P ABC transporter permease
NHGDMEJD_01658 4.9e-140 potC P ABC transporter permease
NHGDMEJD_01659 1.4e-104 potD P ABC transporter
NHGDMEJD_01660 3.1e-86 potD P ABC transporter
NHGDMEJD_01661 5.8e-71
NHGDMEJD_01662 7.4e-95 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHGDMEJD_01663 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NHGDMEJD_01664 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHGDMEJD_01665 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
NHGDMEJD_01666 5.2e-184 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHGDMEJD_01667 5.4e-49 yazA L GIY-YIG catalytic domain protein
NHGDMEJD_01668 3.7e-142 yabB 2.1.1.223 L Methyltransferase small domain
NHGDMEJD_01669 2.7e-76 plsC 2.3.1.51 I Acyltransferase
NHGDMEJD_01670 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
NHGDMEJD_01671 1.4e-10 ynzC S UPF0291 protein
NHGDMEJD_01672 1.1e-09 ynzC S UPF0291 protein
NHGDMEJD_01673 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHGDMEJD_01674 1.5e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NHGDMEJD_01675 8.4e-130 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHGDMEJD_01677 1.6e-45 S Phage gp6-like head-tail connector protein
NHGDMEJD_01678 1.5e-76 S Transcriptional regulator, RinA family
NHGDMEJD_01679 2.3e-284 S Caudovirus prohead serine protease
NHGDMEJD_01680 4.2e-172 S Phage portal protein
NHGDMEJD_01681 3.3e-24 S Phage portal protein
NHGDMEJD_01683 0.0 terL S overlaps another CDS with the same product name
NHGDMEJD_01684 2.1e-79 terS L Phage terminase, small subunit
NHGDMEJD_01686 2.4e-78 L HNH nucleases
NHGDMEJD_01688 5e-12 S head-tail joining protein
NHGDMEJD_01689 1.2e-274 S Phage plasmid primase, P4
NHGDMEJD_01693 1.3e-81 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHGDMEJD_01694 3e-181 yfeX P Peroxidase
NHGDMEJD_01695 2.1e-233 arcD S C4-dicarboxylate anaerobic carrier
NHGDMEJD_01696 6.4e-262 ytjP 3.5.1.18 E Dipeptidase
NHGDMEJD_01697 4.4e-217 uhpT EGP Major facilitator Superfamily
NHGDMEJD_01698 1.9e-281 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NHGDMEJD_01699 1.1e-83 ponA V Beta-lactamase enzyme family
NHGDMEJD_01700 1.5e-104 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHGDMEJD_01701 8.2e-24 XK27_00915 C Luciferase-like monooxygenase
NHGDMEJD_01702 1.1e-156 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NHGDMEJD_01703 8.8e-47 S Protein of unknown function (DUF3021)
NHGDMEJD_01704 2.9e-78 K LytTr DNA-binding domain
NHGDMEJD_01705 2.5e-97 K Acetyltransferase (GNAT) family
NHGDMEJD_01706 3.7e-22
NHGDMEJD_01707 7.6e-121 ybhL S Belongs to the BI1 family
NHGDMEJD_01708 5.8e-82 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NHGDMEJD_01709 8.2e-115 S Protein of unknown function (DUF3114)
NHGDMEJD_01710 1.3e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NHGDMEJD_01711 2.7e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NHGDMEJD_01712 1.3e-110 yvdD 3.2.2.10 S Belongs to the LOG family
NHGDMEJD_01713 7e-62 S Domain of unknown function (DUF4828)
NHGDMEJD_01714 1.1e-116 mocA S Oxidoreductase
NHGDMEJD_01715 2e-45 mocA S Oxidoreductase
NHGDMEJD_01716 3.6e-233 yfmL 3.6.4.13 L DEAD DEAH box helicase
NHGDMEJD_01718 3.3e-211 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHGDMEJD_01719 1.5e-74 gtcA S Teichoic acid glycosylation protein
NHGDMEJD_01720 2.1e-79 fld C Flavodoxin
NHGDMEJD_01721 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
NHGDMEJD_01724 4.8e-252 mmuP E amino acid
NHGDMEJD_01725 5.7e-126 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NHGDMEJD_01726 4.5e-14 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NHGDMEJD_01727 1.3e-70 O Preprotein translocase subunit SecB
NHGDMEJD_01728 3.5e-157 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NHGDMEJD_01729 2.4e-170 whiA K May be required for sporulation
NHGDMEJD_01731 1.6e-14
NHGDMEJD_01732 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHGDMEJD_01733 1.7e-102 L Transposase
NHGDMEJD_01734 1.7e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
NHGDMEJD_01735 7.1e-158 XK27_04590 S NADPH-dependent FMN reductase
NHGDMEJD_01736 1e-78 fld C Flavodoxin
NHGDMEJD_01737 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
NHGDMEJD_01738 3.1e-93 P Cadmium resistance transporter
NHGDMEJD_01739 5.9e-117 pgm1 3.1.3.73 G phosphoglycerate mutase
NHGDMEJD_01740 1.9e-149 3.1.3.48 T Pfam:Y_phosphatase3C
NHGDMEJD_01741 5.5e-56 pduU E BMC
NHGDMEJD_01742 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHGDMEJD_01743 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
NHGDMEJD_01744 3.1e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
NHGDMEJD_01745 7.4e-80 pduO S Haem-degrading
NHGDMEJD_01746 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
NHGDMEJD_01747 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
NHGDMEJD_01748 6.4e-90 S Putative propanediol utilisation
NHGDMEJD_01749 1.1e-53 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NHGDMEJD_01750 7.3e-40 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NHGDMEJD_01751 7.6e-43 pduA_4 CQ BMC
NHGDMEJD_01752 5.1e-75 pduK CQ BMC
NHGDMEJD_01753 1.7e-60 pduH S Dehydratase medium subunit
NHGDMEJD_01754 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
NHGDMEJD_01755 2.1e-80 pduE 4.2.1.28 Q Dehydratase small subunit
NHGDMEJD_01756 9e-22 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
NHGDMEJD_01757 1.9e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHGDMEJD_01758 7.4e-204 XK27_09615 S reductase
NHGDMEJD_01759 2.9e-102 nqr 1.5.1.36 S reductase
NHGDMEJD_01761 1.3e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHGDMEJD_01762 1.5e-183 K Transcriptional regulator, LacI family
NHGDMEJD_01763 5.5e-261 G Major Facilitator
NHGDMEJD_01764 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHGDMEJD_01765 6.2e-102 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NHGDMEJD_01766 7.8e-138 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NHGDMEJD_01767 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
NHGDMEJD_01768 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHGDMEJD_01769 1.2e-25 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NHGDMEJD_01770 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NHGDMEJD_01771 1.2e-10 S Protein of unknown function (DUF4044)
NHGDMEJD_01772 7.8e-58
NHGDMEJD_01773 3.1e-77 mraZ K Belongs to the MraZ family
NHGDMEJD_01774 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHGDMEJD_01775 1.5e-56 ftsL D Cell division protein FtsL
NHGDMEJD_01776 2.2e-31 ftsI 3.4.16.4 M Penicillin-binding Protein
NHGDMEJD_01777 2.1e-38 ftsI 3.4.16.4 M Penicillin-binding Protein
NHGDMEJD_01778 1.7e-301 ftsI 3.4.16.4 M Penicillin-binding Protein
NHGDMEJD_01779 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHGDMEJD_01780 3e-196 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHGDMEJD_01781 5.6e-39 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHGDMEJD_01782 9.2e-206 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHGDMEJD_01783 3.2e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHGDMEJD_01784 1.7e-191 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHGDMEJD_01785 1.5e-73 rafA 3.2.1.22 G alpha-galactosidase
NHGDMEJD_01786 0.0 rafA 3.2.1.22 G alpha-galactosidase
NHGDMEJD_01787 6.3e-193 galR K Periplasmic binding protein-like domain
NHGDMEJD_01788 1.4e-80 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NHGDMEJD_01789 2.5e-80 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NHGDMEJD_01790 5.8e-106 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHGDMEJD_01791 6.2e-61 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHGDMEJD_01792 2.6e-124 lrgB M LrgB-like family
NHGDMEJD_01793 1.9e-66 lrgA S LrgA family
NHGDMEJD_01794 7.7e-103 lytT K response regulator receiver
NHGDMEJD_01795 4.1e-15 lytT K response regulator receiver
NHGDMEJD_01796 9.6e-261 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NHGDMEJD_01797 2.4e-52 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NHGDMEJD_01798 1.8e-28 f42a O Band 7 protein
NHGDMEJD_01799 2.8e-86 f42a O Band 7 protein
NHGDMEJD_01800 2.2e-102 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NHGDMEJD_01801 2.7e-154 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NHGDMEJD_01802 3.7e-139 yitU 3.1.3.104 S hydrolase
NHGDMEJD_01803 3.2e-39 S Cytochrome B5
NHGDMEJD_01804 1.2e-117 nreC K PFAM regulatory protein LuxR
NHGDMEJD_01805 1.5e-161 hipB K Helix-turn-helix
NHGDMEJD_01806 2.8e-57 yitW S Iron-sulfur cluster assembly protein
NHGDMEJD_01807 1e-27 sufB O assembly protein SufB
NHGDMEJD_01808 1.2e-156 sufB O assembly protein SufB
NHGDMEJD_01809 1e-26 sufB O assembly protein SufB
NHGDMEJD_01810 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
NHGDMEJD_01811 1.6e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHGDMEJD_01812 2.1e-171 sufD O FeS assembly protein SufD
NHGDMEJD_01813 2.6e-48 sufD O FeS assembly protein SufD
NHGDMEJD_01814 6.5e-145 sufC O FeS assembly ATPase SufC
NHGDMEJD_01815 1.2e-31 feoA P FeoA domain
NHGDMEJD_01816 4.6e-252 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NHGDMEJD_01817 4.1e-107 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NHGDMEJD_01818 5.5e-19
NHGDMEJD_01819 1.9e-239 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NHGDMEJD_01820 1.4e-10 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NHGDMEJD_01821 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NHGDMEJD_01822 5.6e-255 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHGDMEJD_01823 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHGDMEJD_01824 2.7e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
NHGDMEJD_01825 6e-280 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHGDMEJD_01827 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHGDMEJD_01828 8.1e-199 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHGDMEJD_01829 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
NHGDMEJD_01831 7.5e-58
NHGDMEJD_01832 1.6e-182 prmA J Ribosomal protein L11 methyltransferase
NHGDMEJD_01833 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHGDMEJD_01834 9.3e-53
NHGDMEJD_01835 1.5e-10 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHGDMEJD_01836 1.5e-161 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHGDMEJD_01837 4.9e-204 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHGDMEJD_01838 1.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHGDMEJD_01839 2.8e-170 yniA G Phosphotransferase enzyme family
NHGDMEJD_01840 3e-09 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHGDMEJD_01841 1.6e-301 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHGDMEJD_01842 1.2e-111 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NHGDMEJD_01843 1.1e-136 S Putative adhesin
NHGDMEJD_01844 6.2e-79 XK27_06920 S Protein of unknown function (DUF1700)
NHGDMEJD_01845 1.1e-56 K transcriptional regulator PadR family
NHGDMEJD_01847 2.4e-27 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHGDMEJD_01849 3.4e-48
NHGDMEJD_01850 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHGDMEJD_01851 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHGDMEJD_01852 4.6e-134 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHGDMEJD_01853 9.9e-49 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHGDMEJD_01854 2.1e-249 M Glycosyl transferase family group 2
NHGDMEJD_01856 7e-228 aadAT EK Aminotransferase, class I
NHGDMEJD_01857 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHGDMEJD_01858 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHGDMEJD_01859 2.3e-34 nusG K Participates in transcription elongation, termination and antitermination
NHGDMEJD_01860 6.2e-36 nusG K Participates in transcription elongation, termination and antitermination
NHGDMEJD_01861 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHGDMEJD_01862 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHGDMEJD_01863 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHGDMEJD_01864 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHGDMEJD_01865 2.6e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHGDMEJD_01866 1e-207 yacL S domain protein
NHGDMEJD_01867 2e-138 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHGDMEJD_01868 4.5e-121 ftsK D Belongs to the FtsK SpoIIIE SftA family
NHGDMEJD_01869 4.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHGDMEJD_01870 4.4e-163 rrmA 2.1.1.187 H Methyltransferase
NHGDMEJD_01871 7e-184 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NHGDMEJD_01873 1.4e-242 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NHGDMEJD_01874 2.3e-267 G Major Facilitator
NHGDMEJD_01875 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NHGDMEJD_01876 0.0 M domain protein
NHGDMEJD_01877 2.7e-277 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NHGDMEJD_01878 2e-275 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHGDMEJD_01879 1.4e-30
NHGDMEJD_01880 1.7e-73 K Transcriptional regulator, TetR family
NHGDMEJD_01882 5.5e-248 steT_1 E amino acid
NHGDMEJD_01883 6.4e-139 puuD S peptidase C26
NHGDMEJD_01884 1e-81 tlpA2 L Transposase IS200 like
NHGDMEJD_01885 2e-310 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NHGDMEJD_01886 1.2e-94 mleR K LysR family
NHGDMEJD_01887 7.8e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHGDMEJD_01888 9.4e-49 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NHGDMEJD_01889 2.4e-136 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NHGDMEJD_01890 2.3e-300 L PFAM plasmid pRiA4b ORF-3 family protein
NHGDMEJD_01891 8.1e-47 S Uncharacterized protein conserved in bacteria (DUF2252)
NHGDMEJD_01892 1.3e-182 S Uncharacterized protein conserved in bacteria (DUF2252)
NHGDMEJD_01893 3.1e-203 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NHGDMEJD_01894 3e-75
NHGDMEJD_01895 9.6e-286 S C4-dicarboxylate anaerobic carrier
NHGDMEJD_01896 6.5e-127 pgm3 3.1.3.73 G phosphoglycerate mutase family
NHGDMEJD_01897 1.3e-41
NHGDMEJD_01898 2e-30 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHGDMEJD_01899 1.9e-256 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHGDMEJD_01900 1.4e-90 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NHGDMEJD_01901 1.1e-211 gldA 1.1.1.6 C dehydrogenase
NHGDMEJD_01902 1.5e-126 S Alpha beta hydrolase
NHGDMEJD_01903 7.1e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHGDMEJD_01904 1.5e-103
NHGDMEJD_01906 1e-71 yciB M ErfK YbiS YcfS YnhG
NHGDMEJD_01907 8.8e-96 S Putative peptidoglycan binding domain
NHGDMEJD_01908 7.7e-44 S Putative peptidoglycan binding domain
NHGDMEJD_01909 9.9e-112 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NHGDMEJD_01910 2.4e-89
NHGDMEJD_01911 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NHGDMEJD_01912 5.1e-218 yttB EGP Major facilitator Superfamily
NHGDMEJD_01913 9.3e-101
NHGDMEJD_01914 1e-24
NHGDMEJD_01915 5.5e-175 scrR K Transcriptional regulator, LacI family
NHGDMEJD_01916 6.1e-246 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHGDMEJD_01917 1.6e-41 S Cytochrome B5
NHGDMEJD_01918 1.5e-07 S Cytochrome B5
NHGDMEJD_01919 1.8e-39 S Cytochrome B5
NHGDMEJD_01920 2.4e-77 elaA S Gnat family
NHGDMEJD_01921 1e-72 GM NmrA-like family
NHGDMEJD_01922 2.5e-52 hxlR K Transcriptional regulator, HxlR family
NHGDMEJD_01923 2.5e-08 XK27_02070 S Nitroreductase family
NHGDMEJD_01924 2e-91 XK27_02070 S Nitroreductase family
NHGDMEJD_01925 6.2e-84 K Transcriptional regulator, HxlR family
NHGDMEJD_01926 8.5e-243
NHGDMEJD_01927 2e-211 EGP Major facilitator Superfamily
NHGDMEJD_01928 1.2e-210 pepC 3.4.22.40 E aminopeptidase
NHGDMEJD_01929 3e-18 pepC 3.4.22.40 E aminopeptidase
NHGDMEJD_01930 9.6e-115 ylbE GM NAD dependent epimerase dehydratase family protein
NHGDMEJD_01931 0.0 pepN 3.4.11.2 E aminopeptidase
NHGDMEJD_01932 6.7e-73 folT S ECF transporter, substrate-specific component
NHGDMEJD_01933 1.7e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
NHGDMEJD_01934 6e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NHGDMEJD_01935 9.8e-126 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NHGDMEJD_01936 1.1e-206 2.7.7.65 T GGDEF domain
NHGDMEJD_01937 7.5e-91
NHGDMEJD_01938 7.4e-149
NHGDMEJD_01939 0.0
NHGDMEJD_01941 1.1e-33 S Domain of unknown function (DUF3173)
NHGDMEJD_01942 2e-188 L Belongs to the 'phage' integrase family
NHGDMEJD_01943 1.3e-224 oxlT P Major Facilitator Superfamily
NHGDMEJD_01944 3.2e-161 spoU 2.1.1.185 J Methyltransferase
NHGDMEJD_01945 1.2e-85 ywlG S Belongs to the UPF0340 family
NHGDMEJD_01946 7.1e-201 EGP Major facilitator Superfamily
NHGDMEJD_01947 4.2e-123 M Lysin motif
NHGDMEJD_01948 7.3e-80
NHGDMEJD_01949 3.9e-89 wecD3 K PFAM GCN5-related N-acetyltransferase
NHGDMEJD_01950 2.6e-141 cytX U Belongs to the purine-cytosine permease (2.A.39) family
NHGDMEJD_01951 3.2e-62 cytX U Belongs to the purine-cytosine permease (2.A.39) family
NHGDMEJD_01952 3.3e-13
NHGDMEJD_01953 3.4e-82 S Domain of unknown function (DUF4767)
NHGDMEJD_01954 2e-27
NHGDMEJD_01955 2.5e-39 S Cytochrome B5
NHGDMEJD_01956 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHGDMEJD_01957 1.4e-44 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NHGDMEJD_01958 3.1e-122 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NHGDMEJD_01959 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NHGDMEJD_01960 2.7e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NHGDMEJD_01961 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
NHGDMEJD_01962 1.3e-84 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHGDMEJD_01963 1.8e-167 S KAP family P-loop domain
NHGDMEJD_01964 1.9e-53 S KAP family P-loop domain
NHGDMEJD_01965 1.8e-49 S KAP family P-loop domain
NHGDMEJD_01966 6.6e-46 S KAP family P-loop domain
NHGDMEJD_01967 2.8e-264 S Protein of unknown function (DUF2971)
NHGDMEJD_01968 1.8e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHGDMEJD_01969 7.9e-168 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHGDMEJD_01970 6e-22 epsB M biosynthesis protein
NHGDMEJD_01971 2.3e-171 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NHGDMEJD_01972 2.2e-69 K Transcriptional regulator, HxlR family
NHGDMEJD_01973 2e-94
NHGDMEJD_01974 1e-110 K Bacterial regulatory proteins, tetR family
NHGDMEJD_01975 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NHGDMEJD_01976 3.4e-77 ctsR K Belongs to the CtsR family
NHGDMEJD_01977 1.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
NHGDMEJD_01978 1e-148 S Hydrolases of the alpha beta superfamily
NHGDMEJD_01981 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHGDMEJD_01982 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
NHGDMEJD_01983 7.4e-79 rlpA M PFAM NLP P60 protein
NHGDMEJD_01984 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHGDMEJD_01985 5.4e-80 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHGDMEJD_01986 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHGDMEJD_01987 2.6e-58 yodB K Transcriptional regulator, HxlR family
NHGDMEJD_01988 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHGDMEJD_01989 1.1e-14 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHGDMEJD_01990 4.4e-82 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHGDMEJD_01991 1.7e-308 uup S ABC transporter, ATP-binding protein
NHGDMEJD_01992 6.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHGDMEJD_01994 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHGDMEJD_01995 7.5e-70 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
NHGDMEJD_01996 5.7e-71
NHGDMEJD_01997 8e-140 K Belongs to the N(4) N(6)-methyltransferase family
NHGDMEJD_01999 1e-218 nupG F Nucleoside transporter
NHGDMEJD_02000 2.4e-44 cycA E Amino acid permease
NHGDMEJD_02001 1.3e-116 cycA E Amino acid permease
NHGDMEJD_02002 1.9e-27 cycA E Amino acid permease
NHGDMEJD_02003 8.5e-139 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NHGDMEJD_02004 1e-265 glnP P ABC transporter
NHGDMEJD_02005 2.2e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHGDMEJD_02006 6.8e-297 fhaB M Rib/alpha-like repeat
NHGDMEJD_02019 1.1e-101 2.3.1.128 K Acetyltransferase (GNAT) domain
NHGDMEJD_02020 4.2e-240 lmrB EGP Major facilitator Superfamily
NHGDMEJD_02021 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NHGDMEJD_02022 1.9e-09 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHGDMEJD_02023 3.1e-92 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHGDMEJD_02024 4.6e-161 sufD O Uncharacterized protein family (UPF0051)
NHGDMEJD_02025 2.4e-40 lytE M LysM domain protein
NHGDMEJD_02026 5.8e-151 xth 3.1.11.2 L exodeoxyribonuclease III
NHGDMEJD_02027 7.3e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NHGDMEJD_02028 4e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
NHGDMEJD_02029 3.5e-76 yeaE S Aldo keto
NHGDMEJD_02030 2.1e-71 yeaE S Aldo keto
NHGDMEJD_02031 7e-53 hsp O Belongs to the small heat shock protein (HSP20) family
NHGDMEJD_02032 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NHGDMEJD_02033 1.5e-58 S Psort location Cytoplasmic, score
NHGDMEJD_02034 2.2e-85 S Short repeat of unknown function (DUF308)
NHGDMEJD_02035 1e-23
NHGDMEJD_02036 5.3e-97 cycA E Amino acid permease
NHGDMEJD_02037 4.2e-122 cycA E Amino acid permease
NHGDMEJD_02038 4.3e-85 perR P Belongs to the Fur family
NHGDMEJD_02039 3.7e-123 EGP Major facilitator Superfamily
NHGDMEJD_02040 2.2e-94 EGP Major facilitator Superfamily
NHGDMEJD_02041 8.9e-09 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHGDMEJD_02042 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHGDMEJD_02043 5.3e-264 nox C NADH oxidase
NHGDMEJD_02044 2.1e-70 hmpT S ECF-type riboflavin transporter, S component
NHGDMEJD_02045 1.8e-284 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NHGDMEJD_02046 1.5e-32 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NHGDMEJD_02047 9.2e-169 yvgN C Aldo keto reductase
NHGDMEJD_02048 1.2e-39 puuD S peptidase C26
NHGDMEJD_02049 4.3e-89 puuD S peptidase C26
NHGDMEJD_02050 2.1e-29 L Transposase
NHGDMEJD_02051 1.7e-57 L PFAM Integrase catalytic region
NHGDMEJD_02052 1.1e-96 L Helix-turn-helix domain
NHGDMEJD_02053 1.1e-115 L PFAM Integrase, catalytic core
NHGDMEJD_02054 7.8e-38 L Helix-turn-helix domain
NHGDMEJD_02055 1.4e-101 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NHGDMEJD_02056 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NHGDMEJD_02057 3.1e-103 M NlpC P60 family protein
NHGDMEJD_02058 4e-49 mltD CBM50 M NlpC P60 family protein
NHGDMEJD_02059 5.7e-29
NHGDMEJD_02060 3.3e-64 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NHGDMEJD_02061 5.5e-109 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NHGDMEJD_02062 9.8e-32 ykzG S Belongs to the UPF0356 family
NHGDMEJD_02063 3.6e-82
NHGDMEJD_02064 5.6e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHGDMEJD_02065 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NHGDMEJD_02066 5.6e-67 arcT 2.6.1.1 E Aminotransferase
NHGDMEJD_02067 2.8e-113 arcT 2.6.1.1 E Aminotransferase
NHGDMEJD_02068 1.7e-257 E Arginine ornithine antiporter
NHGDMEJD_02069 8.4e-189 yjeM E Amino Acid
NHGDMEJD_02070 4.9e-60 yjeM E Amino Acid
NHGDMEJD_02071 3.2e-35 yihY S Belongs to the UPF0761 family
NHGDMEJD_02072 7.4e-101 yihY S Belongs to the UPF0761 family
NHGDMEJD_02073 5e-34 S Protein of unknown function (DUF2922)
NHGDMEJD_02074 2.2e-31
NHGDMEJD_02075 9.3e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
NHGDMEJD_02076 1.1e-149 cps1D M Domain of unknown function (DUF4422)
NHGDMEJD_02077 7e-159
NHGDMEJD_02078 1.3e-139 L Bacterial dnaA protein
NHGDMEJD_02079 1.6e-42 L Integrase core domain
NHGDMEJD_02080 2e-157 L Integrase core domain
NHGDMEJD_02081 7.5e-166 3.6.4.12 L DNA helicase
NHGDMEJD_02082 2.3e-306 S AAA domain, putative AbiEii toxin, Type IV TA system
NHGDMEJD_02083 6.9e-167 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHGDMEJD_02084 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHGDMEJD_02085 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHGDMEJD_02086 5.1e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHGDMEJD_02087 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHGDMEJD_02088 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NHGDMEJD_02089 1.7e-54
NHGDMEJD_02090 1.8e-41 recN L May be involved in recombinational repair of damaged DNA
NHGDMEJD_02091 9.3e-39 recN L May be involved in recombinational repair of damaged DNA
NHGDMEJD_02092 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHGDMEJD_02093 2e-48 L PFAM transposase IS200-family protein
NHGDMEJD_02094 4.5e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHGDMEJD_02095 3.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
NHGDMEJD_02096 9.8e-236 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NHGDMEJD_02097 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHGDMEJD_02098 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHGDMEJD_02099 1.4e-83 rimP J Required for maturation of 30S ribosomal subunits
NHGDMEJD_02100 1.2e-216 nusA K Participates in both transcription termination and antitermination
NHGDMEJD_02101 1e-44 ylxR K Protein of unknown function (DUF448)
NHGDMEJD_02102 4.5e-49 ylxQ J ribosomal protein
NHGDMEJD_02103 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHGDMEJD_02104 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHGDMEJD_02105 1.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHGDMEJD_02106 1.9e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NHGDMEJD_02107 2e-64
NHGDMEJD_02108 3.8e-59
NHGDMEJD_02109 7e-153 L Psort location Cytoplasmic, score
NHGDMEJD_02110 4.9e-164 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NHGDMEJD_02111 1.3e-165 recT L RecT family
NHGDMEJD_02116 6.5e-33
NHGDMEJD_02119 4.9e-103 K BRO family, N-terminal domain
NHGDMEJD_02120 4.3e-27 K Helix-turn-helix XRE-family like proteins
NHGDMEJD_02121 3e-47 3.4.21.88 K Helix-turn-helix domain
NHGDMEJD_02122 1.6e-70 S Pfam:DUF955
NHGDMEJD_02123 8e-75
NHGDMEJD_02125 2.6e-139
NHGDMEJD_02126 2.7e-238 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
NHGDMEJD_02127 7.3e-195 gntT EG Gluconate
NHGDMEJD_02128 1.4e-184 K Transcriptional regulator, LacI family
NHGDMEJD_02129 5.1e-46 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NHGDMEJD_02130 2.2e-229 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NHGDMEJD_02131 2.9e-96
NHGDMEJD_02132 2.1e-25
NHGDMEJD_02133 1.1e-62 asp S Asp23 family, cell envelope-related function
NHGDMEJD_02134 4.4e-91 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NHGDMEJD_02135 3.8e-32
NHGDMEJD_02136 2.3e-29 yqkB S Belongs to the HesB IscA family
NHGDMEJD_02137 2.6e-160 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHGDMEJD_02138 4.2e-294 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NHGDMEJD_02139 1.7e-88
NHGDMEJD_02140 1.5e-59 xerS L Belongs to the 'phage' integrase family
NHGDMEJD_02141 6.8e-99 xerS L Belongs to the 'phage' integrase family
NHGDMEJD_02143 1.4e-41 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHGDMEJD_02144 4.2e-77 marR K Transcriptional regulator, MarR family
NHGDMEJD_02145 3.8e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHGDMEJD_02146 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHGDMEJD_02147 3.3e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NHGDMEJD_02148 1.3e-131 IQ reductase
NHGDMEJD_02149 5.6e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHGDMEJD_02150 2.1e-76 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHGDMEJD_02151 1e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHGDMEJD_02152 1.7e-128 S Phage Mu protein F like protein
NHGDMEJD_02154 6.8e-108 S Domain of unknown function (DUF4355)
NHGDMEJD_02155 8.9e-206 gpG
NHGDMEJD_02156 2.2e-63 S Phage gp6-like head-tail connector protein
NHGDMEJD_02157 3e-53
NHGDMEJD_02158 8.2e-86
NHGDMEJD_02159 1.1e-71
NHGDMEJD_02160 5.1e-124
NHGDMEJD_02161 9.4e-95 S Phage tail assembly chaperone protein, TAC
NHGDMEJD_02162 0.0 D NLP P60 protein
NHGDMEJD_02163 3.9e-175 S Phage tail protein
NHGDMEJD_02164 0.0 S Peptidase family M23
NHGDMEJD_02165 3.3e-85 L PFAM transposase IS200-family protein
NHGDMEJD_02166 7.8e-97 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHGDMEJD_02171 1.1e-229 L Transposase
NHGDMEJD_02172 7.7e-31 L Transposase
NHGDMEJD_02173 1.7e-237 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NHGDMEJD_02174 1.2e-120 L PFAM Integrase catalytic region
NHGDMEJD_02175 1.9e-61 L PFAM transposase IS200-family protein
NHGDMEJD_02176 8.7e-231 L transposase, IS605 OrfB family
NHGDMEJD_02177 9.6e-255 L Transposase IS66 family
NHGDMEJD_02178 6.1e-125 L PFAM Integrase catalytic region
NHGDMEJD_02179 1.7e-113 L PFAM Integrase catalytic region
NHGDMEJD_02180 2.9e-131 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHGDMEJD_02181 5.2e-60 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHGDMEJD_02182 1.2e-35 L PFAM Integrase catalytic region
NHGDMEJD_02183 2e-10 S Uncharacterised protein family (UPF0236)
NHGDMEJD_02184 1.5e-71 L PFAM Integrase catalytic region
NHGDMEJD_02185 3.3e-135 L transposase, IS605 OrfB family
NHGDMEJD_02186 1.8e-36 L PFAM transposase IS200-family protein
NHGDMEJD_02187 3.6e-213 S Uncharacterised protein family (UPF0236)
NHGDMEJD_02188 5.4e-264 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NHGDMEJD_02189 3.8e-84 L transposase, IS605 OrfB family
NHGDMEJD_02190 1.8e-44 L transposase, IS605 OrfB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)